Search of human proteins with 9966805

Search of human proteins with 9966805

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9966805 DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 [Homo
sapiens]
         (859 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9966805 DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 [Homo sapiens]  1700   0.0  
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   183   5e-46
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi...   164   2e-40
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   150   6e-36
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi...   149   8e-36
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                  140   4e-33
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ...   138   2e-32
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          136   9e-32
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         135   2e-31
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi...   133   8e-31
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   132   2e-30
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   132   2e-30
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]    130   5e-30
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]            130   5e-30
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]            130   5e-30
gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo sapi...   129   2e-29
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   123   8e-28
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   122   1e-27
gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens]   122   1e-27
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   121   2e-27
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...   119   9e-27
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...   118   3e-26
gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1 ...   118   3e-26
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...   115   1e-25
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...   115   1e-25
gi|8922976 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 [Homo sapiens]   115   2e-25
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...   115   2e-25
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...   115   2e-25
gi|13129006 nucleolar protein GU2 [Homo sapiens]                      113   9e-25
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi...   112   1e-24

>gi|9966805 DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 [Homo sapiens]
          Length = 859

 Score = 1700 bits (4402), Expect = 0.0
 Identities = 859/859 (100%), Positives = 859/859 (100%)

Query: 1   MKLKDTKSRPKQSSCGKFQTKGIKVVGKWKEVKIDPNMFADGQMDDLVCFEELTDYQLVS 60
           MKLKDTKSRPKQSSCGKFQTKGIKVVGKWKEVKIDPNMFADGQMDDLVCFEELTDYQLVS
Sbjct: 1   MKLKDTKSRPKQSSCGKFQTKGIKVVGKWKEVKIDPNMFADGQMDDLVCFEELTDYQLVS 60

Query: 61  PAKNPSSLFSKEAPKRKAQAVSEEEEEEEGKSSSPKKKIKLKKSKNVATEGTSTQKEFEV 120
           PAKNPSSLFSKEAPKRKAQAVSEEEEEEEGKSSSPKKKIKLKKSKNVATEGTSTQKEFEV
Sbjct: 61  PAKNPSSLFSKEAPKRKAQAVSEEEEEEEGKSSSPKKKIKLKKSKNVATEGTSTQKEFEV 120

Query: 121 KDPELEAQGDDMVCDDPEAGEMTSENLVQTAPKKKKNKGKKGLEPSQSTAAKVPKKAKTW 180
           KDPELEAQGDDMVCDDPEAGEMTSENLVQTAPKKKKNKGKKGLEPSQSTAAKVPKKAKTW
Sbjct: 121 KDPELEAQGDDMVCDDPEAGEMTSENLVQTAPKKKKNKGKKGLEPSQSTAAKVPKKAKTW 180

Query: 181 IPEVHDQKADVSAWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETG 240
           IPEVHDQKADVSAWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETG
Sbjct: 181 IPEVHDQKADVSAWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETG 240

Query: 241 SGKTLAFAIPMIHAVLQWQKRNAAPPPSNTEAPPGETRTEAGAETRSPGKAEAESDALPD 300
           SGKTLAFAIPMIHAVLQWQKRNAAPPPSNTEAPPGETRTEAGAETRSPGKAEAESDALPD
Sbjct: 241 SGKTLAFAIPMIHAVLQWQKRNAAPPPSNTEAPPGETRTEAGAETRSPGKAEAESDALPD 300

Query: 301 DTVIESEALPSDIAAEARAKTGGTVSDQALLFGDDDAGEGPSSLIREKPVPKQNENEEEN 360
           DTVIESEALPSDIAAEARAKTGGTVSDQALLFGDDDAGEGPSSLIREKPVPKQNENEEEN
Sbjct: 301 DTVIESEALPSDIAAEARAKTGGTVSDQALLFGDDDAGEGPSSLIREKPVPKQNENEEEN 360

Query: 361 LDKEQTGNLKQELDDKSATCKAYPKRPLLGLVLTPTRELAVQVKQHIDAVARFTGIKTAI 420
           LDKEQTGNLKQELDDKSATCKAYPKRPLLGLVLTPTRELAVQVKQHIDAVARFTGIKTAI
Sbjct: 361 LDKEQTGNLKQELDDKSATCKAYPKRPLLGLVLTPTRELAVQVKQHIDAVARFTGIKTAI 420

Query: 421 LVGGMSTQKQQRMLNRRPEIVVATPGRLWELIKEKHYHLRNLRQLRCLVVDEADRMVEKG 480
           LVGGMSTQKQQRMLNRRPEIVVATPGRLWELIKEKHYHLRNLRQLRCLVVDEADRMVEKG
Sbjct: 421 LVGGMSTQKQQRMLNRRPEIVVATPGRLWELIKEKHYHLRNLRQLRCLVVDEADRMVEKG 480

Query: 481 HFAELSQLLEMLNDSQYNPKRQTLVFSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQ 540
           HFAELSQLLEMLNDSQYNPKRQTLVFSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQ
Sbjct: 481 HFAELSQLLEMLNDSQYNPKRQTLVFSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQ 540

Query: 541 KIGMRGKPKVIDLTRNEATVETLTETKIHCETDEKDFYLYYFLMQYPGRSLVFANSISCI 600
           KIGMRGKPKVIDLTRNEATVETLTETKIHCETDEKDFYLYYFLMQYPGRSLVFANSISCI
Sbjct: 541 KIGMRGKPKVIDLTRNEATVETLTETKIHCETDEKDFYLYYFLMQYPGRSLVFANSISCI 600

Query: 601 KRLSGLLKVLDIMPLTLHACMHQKQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVI 660
           KRLSGLLKVLDIMPLTLHACMHQKQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVI
Sbjct: 601 KRLSGLLKVLDIMPLTLHACMHQKQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVI 660

Query: 661 HYQVPRTSEIYVHRSGRTARATNEGLSLMLIGPEDVINFKKIYKTLKKDEDIPLFPVQTK 720
           HYQVPRTSEIYVHRSGRTARATNEGLSLMLIGPEDVINFKKIYKTLKKDEDIPLFPVQTK
Sbjct: 661 HYQVPRTSEIYVHRSGRTARATNEGLSLMLIGPEDVINFKKIYKTLKKDEDIPLFPVQTK 720

Query: 721 YMDVVKERIRLARQIEKSEYRNFQACLHNSWIEQAAAALEIELEEDMYKGGKADQQEERR 780
           YMDVVKERIRLARQIEKSEYRNFQACLHNSWIEQAAAALEIELEEDMYKGGKADQQEERR
Sbjct: 721 YMDVVKERIRLARQIEKSEYRNFQACLHNSWIEQAAAALEIELEEDMYKGGKADQQEERR 780

Query: 781 RQKQMKVLKKELRHLLSQPLFTESQKTKYPTQSGKPPLLVSAPSKSESALSCLSKQKKKK 840
           RQKQMKVLKKELRHLLSQPLFTESQKTKYPTQSGKPPLLVSAPSKSESALSCLSKQKKKK
Sbjct: 781 RQKQMKVLKKELRHLLSQPLFTESQKTKYPTQSGKPPLLVSAPSKSESALSCLSKQKKKK 840

Query: 841 TKKPKEPQPEQPQPSTSAN 859
           TKKPKEPQPEQPQPSTSAN
Sbjct: 841 TKKPKEPQPEQPQPSTSAN 859


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  183 bits (465), Expect = 5e-46
 Identities = 122/359 (33%), Positives = 199/359 (55%), Gaps = 34/359 (9%)

Query: 384 PKRPLLGLVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVA 443
           P+R L  LVLTPTRELA Q+ +  +A+    G+++A++VGG+ +  Q   L ++P I++A
Sbjct: 90  PQR-LFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIA 148

Query: 444 TPGRLWELIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQT 503
           TPGRL + ++       NLR L+ LV+DEADR++      E+ ++L+++        R+T
Sbjct: 149 TPGRLIDHLENTKGF--NLRALKYLVMDEADRILNMDFETEVDKILKVIPRD-----RKT 201

Query: 504 LVFSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETL 563
            +FSAT+T               KK+ K       +Q+  ++   K    ++ + TVE L
Sbjct: 202 FLFSATMT---------------KKVQK-------LQRAALKNPVKCAVSSKYQ-TVEKL 238

Query: 564 TETKIHCETDEKDFYLYYFLMQYPGRS-LVFANSISCIKRLSGLLKVLDIMPLTLHACMH 622
            +  I   +  KD YL Y L +  G S ++F ++ +  +R + LL+ L    + LH  M 
Sbjct: 239 QQYYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMS 298

Query: 623 QKQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARAT 682
           Q +RL +L +F      +LLATDVA+RGLDIP V  V+++ +P  S+ Y+HR GRTARA 
Sbjct: 299 QSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAG 358

Query: 683 NEGLSLMLIGPEDVINFKKIYKTLKKDEDIPLFPVQTKYMDVVKERIRLARQIEKSEYR 741
             G ++  +   DV  F++I   + K   +P FP Q   + ++ ER+  A++  + E R
Sbjct: 359 RSGKAITFVTQYDVELFQRIEHLIGK--KLPGFPTQDDEVMMLTERVAEAQRFARMELR 415



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 35/90 (38%), Positives = 52/90 (57%), Gaps = 11/90 (12%)

Query: 182 PEVHDQKADVS----------AWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKL 231
           PE HD   + S           +KDL V   +  A   LG++ PT IQ   +  A++ + 
Sbjct: 4   PEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGR- 62

Query: 232 DILGAAETGSGKTLAFAIPMIHAVLQWQKR 261
           DI+G AETGSGKT AFA+P+++A+L+  +R
Sbjct: 63  DIIGLAETGSGKTGAFALPILNALLETPQR 92


>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
           sapiens]
          Length = 483

 Score =  164 bits (416), Expect = 2e-40
 Identities = 131/444 (29%), Positives = 213/444 (47%), Gaps = 49/444 (11%)

Query: 391 LVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRLWE 450
           LVLTPTRELA Q+ +    + +  G+K  I+VGGM    Q   L+R+P +V+ATPGRL +
Sbjct: 74  LVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVVIATPGRLAD 133

Query: 451 LIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQTLVFSATL 510
            ++  +    +++++R LV+DEADR++E+G       L  +L  +    +RQTL+FSATL
Sbjct: 134 HLRSSNTF--SIKKIRFLVMDEADRLLEQGCTDFTVDLEAIL--AAVPARRQTLLFSATL 189

Query: 511 TLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMR-GKPKVIDLTRNEATVETLTETKIH 569
           T                        D L +  G+   +P   +     +TVE L +  + 
Sbjct: 190 T------------------------DTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLL 225

Query: 570 CETDEKDFYLYYFLMQYPGRS-----LVFANSISCIKRLSGLLKVLDIMPLTLHACMHQK 624
                KD YL + + ++         ++F N+    + L  +L+      + LH+ M QK
Sbjct: 226 VPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQK 285

Query: 625 QRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNE 684
           +R   L +F      +L+ATDVA+RGLDIP VQ VI++  P   +IY+HR GRTARA  +
Sbjct: 286 ERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQ 345

Query: 685 GLSLMLIGPEDVINFKKIYKTLKKDEDIPLFPVQTKYMDVVKERIRLARQIEKSEYRNFQ 744
           G ++ L+   D+     I + +KK   +  F V+   +  +  ++ + R       R  +
Sbjct: 346 GQAITLVTQYDIHLVHAIEEQIKK--KLEEFSVEEAEVLQILTQVNVVR-------RECE 396

Query: 745 ACLHNSWIEQAAAALEIELEEDMYKGGKADQQEERRRQKQMKVLKKELRHLLSQPLFTES 804
             L  +  ++     EI   + +   GK    E +R+ +  K+ +K  R         + 
Sbjct: 397 IKLEAAHFDEKK---EINKRKQLILEGKDPDLEAKRKAELAKIKQKNRRFKEKVEETLKR 453

Query: 805 QKTKYPTQSGKPPLLVSAPSKSES 828
           QK       G+PP     PS S S
Sbjct: 454 QKAGRAGHKGRPP---RTPSGSHS 474



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 23/43 (53%), Positives = 29/43 (67%), Gaps = 1/43 (2%)

Query: 210 LGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPMI 252
           LG   PTP+Q L   PAI +  D LG A+TGSGKT AF +P++
Sbjct: 20  LGLKQPTPVQ-LGCIPAILEGRDCLGCAKTGSGKTAAFVLPIL 61


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  150 bits (378), Expect = 6e-36
 Identities = 131/465 (28%), Positives = 215/465 (46%), Gaps = 69/465 (14%)

Query: 391 LVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRLWE 450
           LVL PTREL +QV      +A+F  I T + VGG+  + Q+  L   P+I++ATPGRL +
Sbjct: 293 LVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAPDILIATPGRLID 352

Query: 451 LIKEKHYHLRN-----LRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQTLV 505
                  HL N     L  +  L++DEADRM+++    ++ +++ M +       RQT++
Sbjct: 353 -------HLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHH-----RQTML 400

Query: 506 FSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTE 565
           FSAT+T   +  A +  K   +              I +     V    R E        
Sbjct: 401 FSATMTDEVKDLASVSLKNPVR--------------IFVNSNTDVAPFLRQE-----FIR 441

Query: 566 TKIHCETDEKDFYLYYFLMQYPGRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQ 625
            + + E D +          +    ++F  +     R+  LL ++ +    LH  + Q Q
Sbjct: 442 IRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQ 501

Query: 626 RLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEG 685
           RL  L +F   +  +L+ATDVAARGLDI  V+ VI++ +P T + YVHR GRTARA   G
Sbjct: 502 RLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAG 561

Query: 686 LSLMLIGPEDVINFKKIYKTLKKDEDIPLFPVQTKYMDVVKERIRLARQIEKSEYRNFQA 745
            S+ L+G ++    K+I K  K      + P      DV+   ++   +IEK E      
Sbjct: 562 RSVSLVGEDERKMLKEIVKAAKAPVKARILP-----QDVI---LKFRDKIEKME------ 607

Query: 746 CLHNSWIEQAAAALEIELEEDMYKGGKADQQEERRRQKQMKVLKKELRHLLSQPLFTESQ 805
                  +   A L++E EE      K  QQ E +     ++L+K    ++ +P     +
Sbjct: 608 -------KDVYAVLQLEAEE------KEMQQSEAQINTAKRLLEKGKEAVVQEP-----E 649

Query: 806 KTKYPTQSGKPPLLVSAPSKSESALSCLSKQKKKKTKKPKEPQPE 850
           ++ + T+  +    + A +  E  L+   K+K+KK  K  + + E
Sbjct: 650 RSWFQTKEERKKEKI-AKALQEFDLALRGKKKRKKFMKDAKKKGE 693



 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 55/198 (27%), Positives = 100/198 (50%), Gaps = 25/198 (12%)

Query: 66  SSLFSKEAPKRKAQAVSEEEEEEEGKSSSPKKKIK---LKKSKNVATEGTSTQKEFEVKD 122
           + + S+   KR A  + E+ E+   K  +  K+ K   L+K K  A EG+  +++ ++++
Sbjct: 102 ADVMSQLKKKRAATTLDEKIEKVRKKRKTEDKEAKSGKLEKEKE-AKEGSEPKEQEDLQE 160

Query: 123 PELEAQGDDMVCDDPEAGEMTSENLVQTAP----KKKKNKGKKGLEPSQSTAAKVPKKAK 178
            + E   D+    D  + +   EN++  A     K +K K KKG E            A 
Sbjct: 161 NDEEGSEDEASETDYSSAD---ENILTKADTLKVKDRKKKKKKGQE------------AG 205

Query: 179 TWIPEVHDQKADVSAWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAE 238
            +  +      ++S ++D+ + RP+L+A++ +GF  PTPIQ   +   +  K DI   A 
Sbjct: 206 GFFEDASQYDENLS-FQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGK-DICACAA 263

Query: 239 TGSGKTLAFAIPMIHAVL 256
           TG+GKT AFA+P++  ++
Sbjct: 264 TGTGKTAAFALPVLERLI 281


>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
           sapiens]
          Length = 670

 Score =  149 bits (377), Expect = 8e-36
 Identities = 108/357 (30%), Positives = 183/357 (51%), Gaps = 44/357 (12%)

Query: 391 LVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRLWE 450
           L+L+PTRELA+Q    +  +         +++GG +   + + L     I+VATPGRL +
Sbjct: 255 LILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVATPGRLLD 314

Query: 451 LIKEKHYHLRNL-----RQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQTLV 505
                  H++N      + L+CLV+DEADR+++ G   EL Q++++L       +RQT++
Sbjct: 315 -------HMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPT-----RRQTML 362

Query: 506 FSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTE 565
           FSAT                T+K++  A++ L  + + +      +D  +  ATV+ L +
Sbjct: 363 FSAT---------------QTRKVEDLARISLKKEPLYVG-----VDDDKANATVDGLEQ 402

Query: 566 TKIHCETDEKDFYLYYFLMQYPGRSL-VFANSISCIKRLSGLLKVLDIMPLTLHACMHQK 624
             + C ++++   L+ FL +   + L VF +S   +K    LL  +D+  L +H    Q 
Sbjct: 403 GYVVCPSEKRFLLLFTFLKKNRKKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQN 462

Query: 625 QRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATN- 683
           +R     QF   +   LL TDVAARGLDIP+V  ++ Y  P   + Y+HR GRTAR  N 
Sbjct: 463 KRTTTFFQFCNADSGTLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNG 522

Query: 684 EGLSLMLIGPEDVINFKKIYKTLKKDEDIPLFPVQTKYMDVVKERIRLARQIEKSEY 740
            G +L+++ PE+ + F +  K  K    +PL      +  +   + +L + IEK+ +
Sbjct: 523 RGHALLILRPEE-LGFLRYLKQSK----VPLSEFDFSWSKISDIQSQLEKLIEKNYF 574



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 54/205 (26%), Positives = 93/205 (45%), Gaps = 28/205 (13%)

Query: 75  KRKAQAVSEEEEEEEGKSSSPKKKIKLKKSKNVATEGTSTQKEFEVKDPELEAQGDDMVC 134
           K+K   V   E +  G S      IK+ KS   +T  T+ +   +  + E + +      
Sbjct: 57  KQKPMNVGLSETQNGGMSQEAVGNIKVTKSPQKSTVLTNGEAAMQSSNSESKKK------ 110

Query: 135 DDPEAGEMTSENLVQTAPKKKKNKGKKGLEPSQSTAAKVPKKAKTWIPEVHDQKADV--- 191
              +  +M ++    T   K +NKGK   E +++T        K   P+  + +++V   
Sbjct: 111 -KKKKRKMVNDAEPDTKKAKTENKGKSEEESAETTKETENNVEK---PDNDEDESEVPSL 166

Query: 192 -----SAWKDL-------FVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAET 239
                 A++D         V    L+A+  +GF+  T IQ  ++ P +  + D+L AA+T
Sbjct: 167 PLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEGR-DLLAAAKT 225

Query: 240 GSGKTLAFAIPMIHAV--LQWQKRN 262
           GSGKTLAF IP +  +  L++  RN
Sbjct: 226 GSGKTLAFLIPAVELIVKLRFMPRN 250



 Score = 30.0 bits (66), Expect = 9.6
 Identities = 30/123 (24%), Positives = 57/123 (46%), Gaps = 5/123 (4%)

Query: 736 EKSEYRNFQACLHNSWIEQAAAALEIELEE-DMYKGGKADQQEERRRQKQMKVLKKELRH 794
           +K E RN +    N   + A+     E +  D+ +     ++ ++ +QK M V   E ++
Sbjct: 11  KKIEKRNLKLRQRNLKFQGASNLTLSETQNGDVSEETMGSRKVKKSKQKPMNVGLSETQN 70

Query: 795 L-LSQPLFTESQKTKYPTQSGKPPLLVSAPSKSESALSCLSKQKKKKTKKPKEPQPEQPQ 853
             +SQ      + TK P +S    +L +  +  +S+ S   K+KKKK K   + +P+  +
Sbjct: 71  GGMSQEAVGNIKVTKSPQKS---TVLTNGEAAMQSSNSESKKKKKKKRKMVNDAEPDTKK 127

Query: 854 PST 856
             T
Sbjct: 128 AKT 130


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score =  140 bits (354), Expect = 4e-33
 Identities = 96/308 (31%), Positives = 158/308 (51%), Gaps = 37/308 (12%)

Query: 390 GLVLTPTRELAVQVKQHIDAVARFTG------IKTAILVGGMSTQKQQRMLNRRPEIVVA 443
           GL++ P+RELA Q    ++   R         ++ A+ +GGMS ++Q   +     ++VA
Sbjct: 260 GLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVA 319

Query: 444 TPGRLWELIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQT 503
           TPGRL +L+++K   + +L   R L +DEADRM++ G   ++  +      S +  +RQT
Sbjct: 320 TPGRLMDLLQKK---MVSLDICRYLALDEADRMIDMGFEGDIRTIF-----SYFKGQRQT 371

Query: 504 LVFSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETL 563
           L+FSAT+                KK+   AK  L+        KP  I++ R  A    +
Sbjct: 372 LLFSATMP---------------KKIQNFAKSALV--------KPVTINVGRAGAASLDV 408

Query: 564 TETKIHCETDEKDFYLYYFLMQYPGRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQ 623
            +   + + + K  YL   L + P   L+FA   + +  +   L +  +  + +H    Q
Sbjct: 409 IQEVEYVKEEAKMVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQ 468

Query: 624 KQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATN 683
           ++R + +E F   +  VL+ATDVA++GLD P +QHVI+Y +P   E YVHR GRT R+ N
Sbjct: 469 EERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGN 528

Query: 684 EGLSLMLI 691
            G++   I
Sbjct: 529 TGIATTFI 536



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 63/242 (26%), Positives = 110/242 (45%), Gaps = 26/242 (10%)

Query: 51  EELTDYQLVSPAKNPSSLFSKEAPKRKAQAVSEEEEEEEGKSS---------SPKKKIKL 101
           E+  DY    P +    L  ++  +R+ +  +EEE+++ G             P+  + L
Sbjct: 28  EDDEDYVPYVPLRQRRQLLLQKLLQRRRKGAAEEEQQDSGSEPRGDEDDIPLGPQSNVSL 87

Query: 102 K------KSKNVATEGTSTQKEFEVKDPELE--AQGDDMVCDDPEAGEMTSENLVQTAPK 153
                  K K  A + ++ +K+ + ++  LE  A+G  ++     A  +T ++ ++T+  
Sbjct: 88  LDQHQHLKEKAEARKESAKEKQLKEEEKILESVAEGRALMSVKEMAKGITYDDPIKTSWT 147

Query: 154 KKKNKGKKGLEPSQSTAAKVPKKAKTWIPEVHDQKADVSAWKDLFVPRPVLRALSFLGFS 213
             +      L  S+    +V KK    + E       + ++K++  P  +LR L   G  
Sbjct: 148 PPRYV----LSMSEERHERVRKKYHILV-EGDGIPPPIKSFKEMKFPAAILRGLKKKGIH 202

Query: 214 APTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPMIHAVLQWQKRNAAPPPSNTEAP 273
            PTPIQ   + P I    D++G A TGSGKTL F +P+I   L+ +KR    P S  E P
Sbjct: 203 HPTPIQIQGI-PTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKR---LPFSKREGP 258

Query: 274 PG 275
            G
Sbjct: 259 YG 260


>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
           [Homo sapiens]
          Length = 406

 Score =  138 bits (347), Expect = 2e-32
 Identities = 111/358 (31%), Positives = 176/358 (49%), Gaps = 81/358 (22%)

Query: 384 PKRPLLGLVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVA 443
           P+R L  LVLTPTRELA Q+ +  +A+    G+++A++VGG+ +  Q   L ++P I++A
Sbjct: 90  PQR-LFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIA 148

Query: 444 TPGRLWELIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQT 503
           TPGRL + ++       NLR L+ LV+DEADR++      E+ ++L+++        R+T
Sbjct: 149 TPGRLIDHLENTKGF--NLRALKYLVMDEADRILNMDFETEVDKILKVIPRD-----RKT 201

Query: 504 LVFSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETL 563
            +FSAT+               TKK+ K       +Q+  ++  P    ++    TVE L
Sbjct: 202 FLFSATM---------------TKKVQK-------LQRAALK-NPVKCAVSSKYQTVEKL 238

Query: 564 TETKIHCETDEKDFYLYYFLMQYPGRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQ 623
            +              YY          +F  S    KRL  L K               
Sbjct: 239 QQ--------------YY----------IFIPSKFKSKRLGSLNKF-------------- 260

Query: 624 KQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATN 683
           K + R+          +LLATDVA+RGLDIP V  V+++ +P  S+ Y+HR GRTARA  
Sbjct: 261 KAKARS----------ILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGR 310

Query: 684 EGLSLMLIGPEDVINFKKIYKTLKKDEDIPLFPVQTKYMDVVKERIRLARQIEKSEYR 741
            G ++  +   DV  F++I   + K   +P FP Q   + ++ ER+  A++  + E R
Sbjct: 311 SGKAITFVTQYDVELFQRIEHLIGK--KLPGFPTQDDEVMMLTERVAEAQRFARMELR 366



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 35/90 (38%), Positives = 52/90 (57%), Gaps = 11/90 (12%)

Query: 182 PEVHDQKADVS----------AWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKL 231
           PE HD   + S           +KDL V   +  A   LG++ PT IQ   +  A++ + 
Sbjct: 4   PEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGR- 62

Query: 232 DILGAAETGSGKTLAFAIPMIHAVLQWQKR 261
           DI+G AETGSGKT AFA+P+++A+L+  +R
Sbjct: 63  DIIGLAETGSGKTGAFALPILNALLETPQR 92


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  136 bits (342), Expect = 9e-32
 Identities = 112/394 (28%), Positives = 190/394 (48%), Gaps = 35/394 (8%)

Query: 391 LVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRLWE 450
           LVL PTRELA QV+Q  D   + + +K+  + GG     Q R L R  EI +ATPGRL +
Sbjct: 248 LVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLID 307

Query: 451 LIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQTLVFSATL 510
            ++       NLR+   LV+DEADRM++ G   ++ ++++     Q  P RQTL++SAT 
Sbjct: 308 FLESGK---TNLRRCTYLVLDEADRMLDMGFEPQIRKIVD-----QIRPDRQTLMWSATW 359

Query: 511 TLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTETKIHC 570
                        K  +++ +    D     +G       ++L+ N   ++ + +  +  
Sbjct: 360 P------------KEVRQLAEDFLRDYTQINVGN------LELSANHNILQ-IVDVCMES 400

Query: 571 ETDEKDFYLYYFLM-QYPGRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQRLRN 629
           E D K   L   +M +   ++++F  +      L+  ++      + +H    Q +R   
Sbjct: 401 EKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWV 460

Query: 630 LEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEGLSLM 689
           L +F   +  +L+ATDVA+RGLD+  V+ VI+Y  P +SE YVHR GRTAR+TN+G +  
Sbjct: 461 LNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYT 520

Query: 690 LIGPEDVINFKKIYKTLKKDEDIPLFPVQTKYMDVVKERIRLARQIEKSEYRNFQACLHN 749
              P ++   +++ K L++        +  K M +V  R        +S YR   +  + 
Sbjct: 521 FFTPGNLKQARELIKVLEEANQ----AINPKLMQLVDHRGGGGGGGGRSRYRTTSSANNP 576

Query: 750 SWIEQAAAALEIELEEDMYKGGKADQQEERRRQK 783
           + + Q      +   +D   GG+ D    R R +
Sbjct: 577 NLMYQDECDRRLRGVKD---GGRRDSASYRDRSE 607



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 23/53 (43%), Positives = 33/53 (62%), Gaps = 1/53 (1%)

Query: 200 PRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPMI 252
           P+ V+  L    F+ PTPIQ      A+  + D++G A+TGSGKTLA+ +P I
Sbjct: 179 PQYVMDVLMDQHFTEPTPIQCQGFPLALSGR-DMVGIAQTGSGKTLAYLLPAI 230


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  135 bits (339), Expect = 2e-31
 Identities = 102/339 (30%), Positives = 171/339 (50%), Gaps = 32/339 (9%)

Query: 391 LVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRLWE 450
           LVL PTRELA QV+Q  D   + + +K+  + GG     Q R L R  EI +ATPGRL +
Sbjct: 248 LVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLID 307

Query: 451 LIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQTLVFSATL 510
            ++       NLR+   LV+DEADRM++ G   ++ ++++     Q  P RQTL++SAT 
Sbjct: 308 FLESGK---TNLRRCTYLVLDEADRMLDMGFEPQIRKIVD-----QIRPDRQTLMWSATW 359

Query: 511 TLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTETKIHC 570
                        K  +++ +    D     +G       ++L+ N   ++ + +  +  
Sbjct: 360 P------------KEVRQLAEDFLRDYTQINVGN------LELSANHNILQ-IVDVCMES 400

Query: 571 ETDEKDFYLYYFLM-QYPGRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQRLRN 629
           E D K   L   +M +   ++++F  +      L+  ++      + +H    Q +R   
Sbjct: 401 EKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWV 460

Query: 630 LEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEGLSLM 689
           L +F   +  +L+ATDVA+RGLD+  V+ VI+Y  P +SE YVHR GRTAR+TN+G +  
Sbjct: 461 LNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYT 520

Query: 690 LIGPEDVINFKKIYKTLKKDEDIPLFPVQTKYMDVVKER 728
              P ++   +++ K L++        +  K M +V  R
Sbjct: 521 FFTPGNLKQARELIKVLEEANQ----AINPKLMQLVDHR 555



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 23/53 (43%), Positives = 33/53 (62%), Gaps = 1/53 (1%)

Query: 200 PRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPMI 252
           P+ V+  L    F+ PTPIQ      A+  + D++G A+TGSGKTLA+ +P I
Sbjct: 179 PQYVMDVLMDQHFTEPTPIQCQGFPLALSGR-DMVGIAQTGSGKTLAYLLPAI 230


>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
           sapiens]
          Length = 875

 Score =  133 bits (334), Expect = 8e-31
 Identities = 117/413 (28%), Positives = 197/413 (47%), Gaps = 44/413 (10%)

Query: 391 LVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRLWE 450
           L+++PTRELA Q  + +  V +       +++GG   + +   +N    I+V TPGRL +
Sbjct: 145 LIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERINNI-NILVCTPGRLLQ 203

Query: 451 LIKEK-HYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQTLVFSAT 509
            + E   +H  +L+ L   V+DEADR+++ G    ++ ++E L       KRQTL+FSAT
Sbjct: 204 HMDETVSFHATDLQML---VLDEADRILDMGFADTMNAVIENLPK-----KRQTLLFSAT 255

Query: 510 LTLVHQAPARILHKKHTKKMDKTAKLDLLMQK-IGMRGKPKVIDLTRNEATVETLTETKI 568
                           TK +   A+L L   + + +  K K        +T  TL +  I
Sbjct: 256 ---------------QTKSVKDLARLSLKNPEYVWVHEKAKY-------STPATLEQNYI 293

Query: 569 HCETDEKDFYLYYFLMQY-PGRSLVFANSISCIKRLSGLLKVL--DIMPLTLHACMHQKQ 625
            CE  +K   LY FL  +   +S+VF +S   ++ L  +   L   +  L LH    Q +
Sbjct: 294 VCELQQKISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMR 353

Query: 626 RLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEG 685
           R+    +F R    VL ATD+AARGLD P V  V+ +  P  +  Y+HR+GRTAR   +G
Sbjct: 354 RMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDG 413

Query: 686 LSLMLIGPEDVINFKKIYKTLKKDEDIPLFPVQTKYMDVVKERIRLARQ---IEKSEYRN 742
            +L+++ P +    +++ +     ++I + P   K +DV K+   +  Q   +++   R 
Sbjct: 414 EALLILLPSEKAMVQQLLQKKVPVKEIKINP--EKLIDVQKKLESILAQDQDLKERAQRC 471

Query: 743 FQACLHNSWIEQAAAALEIE---LEEDMYKGGKADQQEERRRQKQMKVLKKEL 792
           F + + + ++ +     ++    + E     G A     R  QK  K   KEL
Sbjct: 472 FVSYVRSVYLMKDKEVFDVSKLPIPEYALSLGLAVAPRVRFLQKMQKQPTKEL 524



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 28/71 (39%), Positives = 45/71 (63%), Gaps = 3/71 (4%)

Query: 190 DVSAWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAI 249
           +++ + D  + +  L+ L    +   T IQ  T+  A++ K D+LGAA+TGSGKTLAF +
Sbjct: 67  EITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGK-DVLGAAKTGSGKTLAFLV 125

Query: 250 PMIHAV--LQW 258
           P++ A+  LQW
Sbjct: 126 PVLEALYRLQW 136


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  132 bits (331), Expect = 2e-30
 Identities = 141/576 (24%), Positives = 245/576 (42%), Gaps = 74/576 (12%)

Query: 254 AVLQWQK-------RNAAPPPSNTEAPPGETRTEAGAETRS----PGK-------AEAES 295
           A+ QW+K       R AA     +++  GE   +A  + R+    PG+       +E  S
Sbjct: 16  AMAQWRKKKGLRKRRGAASQARGSDSEDGEFEIQAEDDARARKLGPGRPLPTFPTSECTS 75

Query: 296 DALPDDTVIESEALPSDIAAEARAKTGGTVSDQALLFGDDDAGEGPSSLIREKPVPKQNE 355
           D  PD   +         A   + K  G      L +      +G      + P P Q +
Sbjct: 76  DVEPDTREMVR-------AQNKKKKKSGGFQSMGLSY---PVFKGIMKKGYKVPTPIQRK 125

Query: 356 NEEENLDKEQTGNLKQELDDKSATCKAYPKRPLL----------GLVLTPTRELAVQVKQ 405
                LD +    + +    K+A C   P    L           L+L+PTRELA+Q  +
Sbjct: 126 TIPVILDGKDVVAMARTGSGKTA-CFLLPMFERLKTHSAQTGARALILSPTRELALQTLK 184

Query: 406 HIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRLWELIKEKHYHLRNLRQL 465
               + +FTG+KTA+++GG   + Q   L+  P+I++ATPGRL  +  E    L+++  +
Sbjct: 185 FTKELGKFTGLKTALILGGDRMEDQFAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYV 244

Query: 466 RCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQTLVFSATLTLVHQAPARILHKKH 525
              V DEADR+ E G   +L +++  L         QT++FSATL               
Sbjct: 245 ---VFDEADRLFEMGFAEQLQEIIARLPGGH-----QTVLFSATLP-------------- 282

Query: 526 TKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTETKIHCETDEKDFYLYYFL-- 583
                   KL +   + G+  +P +I L  +    E L  +      D K   L + L  
Sbjct: 283 --------KLLVEFARAGLT-EPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLHLLHN 333

Query: 584 -MQYPGRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQRLRNLEQFARLEDCVLL 642
            ++   +++VF  +    + L+ LL    +    +++ +    R  NL +F   +   L+
Sbjct: 334 VVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLI 393

Query: 643 ATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEGLSLMLIGPEDVINFKKI 702
            TD+AARGLDIP + +VI+Y  P   ++++HR GR ARA   G +  L+ P+++     +
Sbjct: 394 VTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDL 453

Query: 703 YKTLKKDEDIPLFPVQTKYMDVVKERI-RLARQIEKSEYRNFQACLHNSWIEQAAAALEI 761
           +  L +   +     +   +  V   + R+ + +   E    Q+ L  S   +  A +  
Sbjct: 454 HLFLGRSLTLARPLKEPSGVAGVDGMLGRVPQSVVDEEDSGLQSTLEASLELRGLARVAD 513

Query: 762 ELEEDMYKGGKADQQEERRRQKQMKVLKKELRHLLS 797
             ++   +   A   E  +R K+M ++   L  L S
Sbjct: 514 NAQQQYVRSRPAPSPESIKRAKEMDLVGLGLHPLFS 549



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 42/156 (26%), Positives = 67/156 (42%), Gaps = 22/156 (14%)

Query: 96  KKKIKLKKSKNVATEGTSTQKEFEVKDPELEAQGDDMVCDDPEAGEMTSENLVQTAPKKK 155
           +KK  L+K +  A++   +  E    D E E Q +D    D  A ++     + T P  +
Sbjct: 21  RKKKGLRKRRGAASQARGSDSE----DGEFEIQAED----DARARKLGPGRPLPTFPTSE 72

Query: 156 KNKGKKGLEPSQSTAAKVPKKAKTWIPEVHDQKADVSAWKDLFVPRPVLRALSFLGFSAP 215
                  +EP      +   K          +K     ++ + +  PV + +   G+  P
Sbjct: 73  CTSD---VEPDTREMVRAQNK----------KKKKSGGFQSMGLSYPVFKGIMKKGYKVP 119

Query: 216 TPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPM 251
           TPIQ  T+ P I D  D++  A TGSGKT  F +PM
Sbjct: 120 TPIQRKTI-PVILDGKDVVAMARTGSGKTACFLLPM 154


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  132 bits (331), Expect = 2e-30
 Identities = 141/576 (24%), Positives = 245/576 (42%), Gaps = 74/576 (12%)

Query: 254 AVLQWQK-------RNAAPPPSNTEAPPGETRTEAGAETRS----PGK-------AEAES 295
           A+ QW+K       R AA     +++  GE   +A  + R+    PG+       +E  S
Sbjct: 16  AMAQWRKKKGLRKRRGAASQARGSDSEDGEFEIQAEDDARARKLGPGRPLPTFPTSECTS 75

Query: 296 DALPDDTVIESEALPSDIAAEARAKTGGTVSDQALLFGDDDAGEGPSSLIREKPVPKQNE 355
           D  PD   +         A   + K  G      L +      +G      + P P Q +
Sbjct: 76  DVEPDTREMVR-------AQNKKKKKSGGFQSMGLSY---PVFKGIMKKGYKVPTPIQRK 125

Query: 356 NEEENLDKEQTGNLKQELDDKSATCKAYPKRPLL----------GLVLTPTRELAVQVKQ 405
                LD +    + +    K+A C   P    L           L+L+PTRELA+Q  +
Sbjct: 126 TIPVILDGKDVVAMARTGSGKTA-CFLLPMFERLKTHSAQTGARALILSPTRELALQTLK 184

Query: 406 HIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRLWELIKEKHYHLRNLRQL 465
               + +FTG+KTA+++GG   + Q   L+  P+I++ATPGRL  +  E    L+++  +
Sbjct: 185 FTKELGKFTGLKTALILGGDRMEDQFAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYV 244

Query: 466 RCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQTLVFSATLTLVHQAPARILHKKH 525
              V DEADR+ E G   +L +++  L         QT++FSATL               
Sbjct: 245 ---VFDEADRLFEMGFAEQLQEIIARLPGGH-----QTVLFSATLP-------------- 282

Query: 526 TKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTETKIHCETDEKDFYLYYFL-- 583
                   KL +   + G+  +P +I L  +    E L  +      D K   L + L  
Sbjct: 283 --------KLLVEFARAGLT-EPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLHLLHN 333

Query: 584 -MQYPGRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQRLRNLEQFARLEDCVLL 642
            ++   +++VF  +    + L+ LL    +    +++ +    R  NL +F   +   L+
Sbjct: 334 VVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLI 393

Query: 643 ATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEGLSLMLIGPEDVINFKKI 702
            TD+AARGLDIP + +VI+Y  P   ++++HR GR ARA   G +  L+ P+++     +
Sbjct: 394 VTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDL 453

Query: 703 YKTLKKDEDIPLFPVQTKYMDVVKERI-RLARQIEKSEYRNFQACLHNSWIEQAAAALEI 761
           +  L +   +     +   +  V   + R+ + +   E    Q+ L  S   +  A +  
Sbjct: 454 HLFLGRSLTLARPLKEPSGVAGVDGMLGRVPQSVVDEEDSGLQSTLEASLELRGLARVAD 513

Query: 762 ELEEDMYKGGKADQQEERRRQKQMKVLKKELRHLLS 797
             ++   +   A   E  +R K+M ++   L  L S
Sbjct: 514 NAQQQYVRSRPAPSPESIKRAKEMDLVGLGLHPLFS 549



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 42/156 (26%), Positives = 67/156 (42%), Gaps = 22/156 (14%)

Query: 96  KKKIKLKKSKNVATEGTSTQKEFEVKDPELEAQGDDMVCDDPEAGEMTSENLVQTAPKKK 155
           +KK  L+K +  A++   +  E    D E E Q +D    D  A ++     + T P  +
Sbjct: 21  RKKKGLRKRRGAASQARGSDSE----DGEFEIQAED----DARARKLGPGRPLPTFPTSE 72

Query: 156 KNKGKKGLEPSQSTAAKVPKKAKTWIPEVHDQKADVSAWKDLFVPRPVLRALSFLGFSAP 215
                  +EP      +   K          +K     ++ + +  PV + +   G+  P
Sbjct: 73  CTSD---VEPDTREMVRAQNK----------KKKKSGGFQSMGLSYPVFKGIMKKGYKVP 119

Query: 216 TPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPM 251
           TPIQ  T+ P I D  D++  A TGSGKT  F +PM
Sbjct: 120 TPIQRKTI-PVILDGKDVVAMARTGSGKTACFLLPM 154


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score =  130 bits (327), Expect = 5e-30
 Identities = 101/339 (29%), Positives = 168/339 (49%), Gaps = 32/339 (9%)

Query: 391 LVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRLWE 450
           LVL PTRELA QV+Q      R   +K+  + GG     Q R L R  EI +ATPGRL +
Sbjct: 171 LVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLID 230

Query: 451 LIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQTLVFSATL 510
            ++       NLR+   LV+DEADRM++ G   ++ ++++     Q  P RQTL++SAT 
Sbjct: 231 FLE---CGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVD-----QIRPDRQTLMWSATW 282

Query: 511 TLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTETKIHC 570
                        K  +++ +    D +   IG       ++L+ N   ++ + +     
Sbjct: 283 P------------KEVRQLAEDFLKDYIHINIG------ALELSANHNILQ-IVDVCHDV 323

Query: 571 ETDEKDFYLYYFLM-QYPGRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQRLRN 629
           E DEK   L   +M +   +++VF  +      L+  ++      + +H    Q++R   
Sbjct: 324 EKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWV 383

Query: 630 LEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEGLSLM 689
           L +F   +  +L+ATDVA+RGLD+  V+ VI+Y  P +SE Y+HR GRTAR+T  G +  
Sbjct: 384 LNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYT 443

Query: 690 LIGPEDVINFKKIYKTLKKDEDIPLFPVQTKYMDVVKER 728
              P ++     +   L++        +  K + +V++R
Sbjct: 444 FFTPNNIKQVSDLISVLREANQ----AINPKLLQLVEDR 478



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 32/103 (31%), Positives = 55/103 (53%), Gaps = 3/103 (2%)

Query: 152 PKKKKNKGKKGLEPSQSTAAKVP--KKAKTWIPEVHDQKADVSAWKDLFVPRPVLRALSF 209
           PK +KN  ++  + ++ TA +V   +++K      H+    V  + +   P  V+  ++ 
Sbjct: 52  PKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIAR 111

Query: 210 LGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPMI 252
             F+ PT IQA    P     LD++G A+TGSGKTL++ +P I
Sbjct: 112 QNFTEPTAIQAQGW-PVALSGLDMVGVAQTGSGKTLSYLLPAI 153


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  130 bits (327), Expect = 5e-30
 Identities = 99/309 (32%), Positives = 155/309 (50%), Gaps = 32/309 (10%)

Query: 389 LGLVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRL 448
           + +++ PTREL  Q+        +   +++  + GG S  +Q + L    EIVV TPGRL
Sbjct: 328 IAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRL 387

Query: 449 WELIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQTLVFSA 508
            + +K+K     NL+++  LV DEADRM + G   ++  +      S   P RQTL+FSA
Sbjct: 388 IDHVKKK---ATNLQRVSYLVFDEADRMFDMGFEYQVRSIA-----SHVRPDRQTLLFSA 439

Query: 509 TLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTETKI 568
           T                 KK++K A+ D+L+  I      +V+     EA  +     +I
Sbjct: 440 TFR---------------KKIEKLAR-DILIDPI------RVVQGDIGEANEDVTQIVEI 477

Query: 569 HCETDEKDFYLYYFLMQYP--GRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQR 626
                 K  +L   L+++   G  L+F    +  + L+  LK        LH  M Q +R
Sbjct: 478 LHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSER 537

Query: 627 LRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEGL 686
            + +  F + +  VL+ATDVAARGLDIP ++ VI+Y V R  + + HR GRT RA  +G+
Sbjct: 538 NKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGV 597

Query: 687 SLMLIGPED 695
           +  L+ P+D
Sbjct: 598 AYTLLTPKD 606



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 30/81 (37%), Positives = 43/81 (53%), Gaps = 2/81 (2%)

Query: 212 FSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPM-IHAVLQWQKRNAAPPPSNT 270
           ++ PTPIQ   +  A+  + D++G A+TGSGKT AF  PM IH + Q +      P +  
Sbjct: 273 YTQPTPIQCQGVPVALSGR-DMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVI 331

Query: 271 EAPPGETRTEAGAETRSPGKA 291
             P  E   +  AE +  GKA
Sbjct: 332 VCPTRELCQQIHAECKRFGKA 352


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  130 bits (327), Expect = 5e-30
 Identities = 99/309 (32%), Positives = 155/309 (50%), Gaps = 32/309 (10%)

Query: 389 LGLVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRL 448
           + +++ PTREL  Q+        +   +++  + GG S  +Q + L    EIVV TPGRL
Sbjct: 328 IAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRL 387

Query: 449 WELIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQTLVFSA 508
            + +K+K     NL+++  LV DEADRM + G   ++  +      S   P RQTL+FSA
Sbjct: 388 IDHVKKK---ATNLQRVSYLVFDEADRMFDMGFEYQVRSIA-----SHVRPDRQTLLFSA 439

Query: 509 TLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTETKI 568
           T                 KK++K A+ D+L+  I      +V+     EA  +     +I
Sbjct: 440 TFR---------------KKIEKLAR-DILIDPI------RVVQGDIGEANEDVTQIVEI 477

Query: 569 HCETDEKDFYLYYFLMQYP--GRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQR 626
                 K  +L   L+++   G  L+F    +  + L+  LK        LH  M Q +R
Sbjct: 478 LHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSER 537

Query: 627 LRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEGL 686
            + +  F + +  VL+ATDVAARGLDIP ++ VI+Y V R  + + HR GRT RA  +G+
Sbjct: 538 NKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGV 597

Query: 687 SLMLIGPED 695
           +  L+ P+D
Sbjct: 598 AYTLLTPKD 606



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 30/81 (37%), Positives = 43/81 (53%), Gaps = 2/81 (2%)

Query: 212 FSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPM-IHAVLQWQKRNAAPPPSNT 270
           ++ PTPIQ   +  A+  + D++G A+TGSGKT AF  PM IH + Q +      P +  
Sbjct: 273 YTQPTPIQCQGVPVALSGR-DMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVI 331

Query: 271 EAPPGETRTEAGAETRSPGKA 291
             P  E   +  AE +  GKA
Sbjct: 332 VCPTRELCQQIHAECKRFGKA 352


>gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo
           sapiens]
          Length = 600

 Score =  129 bits (323), Expect = 2e-29
 Identities = 102/328 (31%), Positives = 169/328 (51%), Gaps = 44/328 (13%)

Query: 391 LVLTPTRELAVQVKQHIDAVAR-FTGIKTAILVGGMSTQKQ-QRMLNRRPEIVVATPGRL 448
           +++TPTRELA+Q+ + +    + F      + +GG +  +  +R   +   I+VATPGRL
Sbjct: 86  IIITPTRELAIQIDEVLSHFTKHFPEFSQILWIGGRNPGEDVERFKQQGGNIIVATPGRL 145

Query: 449 WELIKEKHYHL---RNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPK-RQTL 504
            ++ + K   L     +R L  LV+DEADR+++ G  A ++ +LE L      PK R+T 
Sbjct: 146 EDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEASINTILEFL------PKQRRTG 199

Query: 505 VFSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLT 564
           +FSAT                T++++   +  L    + +  K K +  +  + T   L 
Sbjct: 200 LFSAT---------------QTQEVENLVRAGL-RNPVRVSVKEKGVAASSAQKTPSRLE 243

Query: 565 ETKIHCETDEKDFYLYYFLMQYPG-RSLVFANSISCI----KRLSGLLKVLDIMPLTLHA 619
              + C+ DEK   L +FL  +   + LVF ++ +C+    K L  L+K + IM      
Sbjct: 244 NYYMVCKADEKFNQLVHFLRNHKQEKHLVFFSTCACVEYYGKALEVLVKGVKIM------ 297

Query: 620 CMHQKQRLRNLE---QFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSG 676
           C+H K + +  +   +F +L+  +L+ TDV ARG+DIP+V  V+ Y  P  +  +VHR G
Sbjct: 298 CIHGKMKYKRNKIFMEFRKLQSGILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCG 357

Query: 677 RTARATNEGLSLMLIGP--EDVINFKKI 702
           RTAR  + G +L+ + P  E  INF  I
Sbjct: 358 RTARIGHGGSALVFLLPMEESYINFLAI 385



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 31/71 (43%), Positives = 46/71 (64%), Gaps = 3/71 (4%)

Query: 193 AWKDLFVPR--PVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIP 250
           +W+ L VP    VL AL  LGF   TP+Q+ T+   +R+K D+   A TGSGKTLAF IP
Sbjct: 8   SWESLPVPLHPQVLGALRELGFPYMTPVQSATIPLFMRNK-DVAAEAVTGSGKTLAFVIP 66

Query: 251 MIHAVLQWQKR 261
           ++  +L+ +++
Sbjct: 67  ILEILLRREEK 77


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  123 bits (308), Expect = 8e-28
 Identities = 87/319 (27%), Positives = 157/319 (49%), Gaps = 33/319 (10%)

Query: 380 CKAYPKRPLLGLVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPE 439
           C     R    L+L PTRELAVQ+++ + A+  +  ++    +GG +  +  R L+    
Sbjct: 99  CLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQH 158

Query: 440 IVVATPGRLWELIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNP 499
           +V  TPGR++++I+ +    R ++ L   V+DEAD M+ KG   ++  +   L      P
Sbjct: 159 VVAGTPGRVFDMIRRRSLRTRAIKML---VLDEADEMLNKGFKEQIYDVYRYLP-----P 210

Query: 500 KRQTLVFSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEAT 559
             Q ++ SATL      P  IL   +    D                 P  I + R+E T
Sbjct: 211 ATQVVLISATL------PHEILEMTNKFMTD-----------------PIRILVKRDELT 247

Query: 560 VETLTETKIHCETDEKDFYLYYFLMQYPG--RSLVFANSISCIKRLSGLLKVLDIMPLTL 617
           +E + +  +  E +E  F     L       ++++F N+   +  L+  ++  +    ++
Sbjct: 248 LEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSM 307

Query: 618 HACMHQKQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGR 677
           H  M QK+R   +++F      VL++TDV ARGLD+P+V  +I+Y +P   E+Y+HR GR
Sbjct: 308 HGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGR 367

Query: 678 TARATNEGLSLMLIGPEDV 696
           + R   +G+++  +  +D+
Sbjct: 368 SGRYGRKGVAINFVKNDDI 386



 Score = 33.5 bits (75), Expect = 0.87
 Identities = 15/53 (28%), Positives = 31/53 (58%), Gaps = 1/53 (1%)

Query: 203 VLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPMIHAV 255
           +LR +   GF  P+ IQ   +   I+ + D++  +++G+GKT  F+I ++  +
Sbjct: 49  LLRGIYAYGFEKPSAIQQRAIKQIIKGR-DVIAQSQSGTGKTATFSISVLQCL 100


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  122 bits (307), Expect = 1e-27
 Identities = 93/326 (28%), Positives = 153/326 (46%), Gaps = 40/326 (12%)

Query: 389 LGLVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRL 448
           + +++TPTRELA+Q+ +     ++  G++   + GG    +Q   L R  EI+V TPGR+
Sbjct: 447 IAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRM 506

Query: 449 WELIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQTLVFSA 508
            +++      + NLR++  +V+DEADRM + G   ++ ++++        P RQT++FSA
Sbjct: 507 IDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVD-----NVRPDRQTVMFSA 561

Query: 509 TLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTETKI 568
           T     +A AR                        +  KP  + +         + +  I
Sbjct: 562 TFPRAMEALAR-----------------------RILSKPIEVQVGGRSVVCSDVEQQVI 598

Query: 569 HCETDEKDFYLYYFLMQY--PGRSLVFANSISCIKRLSGLLKVLDIMP-----LTLHACM 621
             E ++K   L   L  Y   G  ++F +     +   GLLK  D+M      ++LH  +
Sbjct: 599 VIEEEKKFLKLLELLGHYQESGSVIIFVDK---QEHADGLLK--DLMRASYPCMSLHGGI 653

Query: 622 HQKQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARA 681
            Q  R   +  F      +L+AT VAARGLD+  +  V++Y  P   E YVHR+GRT RA
Sbjct: 654 DQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRA 713

Query: 682 TNEGLSLMLIGPEDVINFKKIYKTLK 707
            N+G +   I  +       I K L+
Sbjct: 714 GNKGYAYTFITEDQARYAGDIIKALE 739



 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 70/304 (23%), Positives = 124/304 (40%), Gaps = 52/304 (17%)

Query: 2   KLKDTKSRPKQSSCGKFQTKGIKV--------VGKWKEVKIDPNMFADGQMDDLVCFEEL 53
           K KD K   K+   G F    ++         V KW+E +    M   G++   +  EE+
Sbjct: 135 KDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEI--EEM 192

Query: 54  TDYQLVSPAKNPSSLFSK-EAPKRKAQAVSEEEEEEEGKSSSPKKKIKLKKSKNVATEGT 112
              +  S   +        EA K   +   EE +  +      K+++K    ++V   G 
Sbjct: 193 KQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGG 252

Query: 113 STQKEFEVKDP------------ELEAQGDDMVCDDPEAGEMTSENL---VQTAPKKKKN 157
           + +K                   + + +  +++ +D +A E +SE     +QTA    + 
Sbjct: 253 NEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQT 312

Query: 158 KGKKGLEP-----------SQSTAAKVPKKAKTWIPEVHDQKAD--------------VS 192
           K +K LEP            ++   +VP+ AK    EV+  + +              + 
Sbjct: 313 KQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIK 372

Query: 193 AWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPMI 252
           +W    +   +L +L   G+  PTPIQ   + PAI    D++G A+TGSGKT+AF +PM 
Sbjct: 373 SWVQCGISMKILNSLKKHGYEKPTPIQTQAI-PAIMSGRDLIGIAKTGSGKTIAFLLPMF 431

Query: 253 HAVL 256
             ++
Sbjct: 432 RHIM 435


>gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens]
          Length = 547

 Score =  122 bits (306), Expect = 1e-27
 Identities = 157/568 (27%), Positives = 239/568 (42%), Gaps = 103/568 (18%)

Query: 327 DQALLFGDDDAGEGPSSLIREKPVPKQNENEEENLDKEQTGNLK---------QELDDKS 377
           D  LL    D G    +LI+EK +P   E ++  L + +TG+ K         Q L  + 
Sbjct: 15  DPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDL-LARARTGSGKTAAYAIPMLQLLLHRK 73

Query: 378 ATCKAYPKRPLLGLVLTPTRELAVQVKQHIDAVARFTG--IKTAILVGGMSTQKQQRMLN 435
           AT     ++ + GLVL PT+ELA Q +  I  +A +    ++ A +     +  Q+ +L 
Sbjct: 74  ATGPVV-EQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVSQRAVLM 132

Query: 436 RRPEIVVATPGRLWELIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDS 495
            +P++VV TP R+   +++    LR+   L  LVVDEAD +   G   EL  LL  L   
Sbjct: 133 EKPDVVVGTPSRILSHLQQDSLKLRD--SLELLVVDEADLLFSFGFEEELKSLLCHL--- 187

Query: 496 QYNPK-RQTLVFSATLTLVHQAPAR-ILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDL 553
              P+  Q  + SAT     QA    ILH   T K+          Q+  + G       
Sbjct: 188 ---PRIYQAFLMSATFNEDVQALKELILHNPVTLKL----------QESQLPGP------ 228

Query: 554 TRNEATVETLTETKIHCETDEKDFYLYYFLMQYP---GRSLVFANSISCIKRLSGLLKVL 610
                  + L + ++ CET+E  F L Y L++     G+SL+F N++    RL   L+  
Sbjct: 229 -------DQLQQFQVVCETEEDKFLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQF 281

Query: 611 DIMPLTLHACMHQKQRLRNLEQFAR-LEDCVLLATDV----------------------- 646
            I    L+  +  + R   + QF +   DCV+ ATD                        
Sbjct: 282 SIPTCVLNGELPLRSRCHIISQFNQGFYDCVI-ATDAEVLGAPVKGKRRGRGPKGDKASD 340

Query: 647 ----AARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEGLSLMLIGPEDVINFKKI 702
                ARG+D   V  V+++ +P T E Y+HR+GRTARA N G+ L  + P +  +  KI
Sbjct: 341 PEAGVARGIDFHHVSAVLNFDLPPTPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKI 400

Query: 703 YKTLKKDEDIP-LFPVQTKYMDVVKERIRLARQIEKSEYRNFQACLHNSWIEQAAAALEI 761
            + L  +   P L P Q +             +IE   YR   A    S  +QA     +
Sbjct: 401 EELLSGENRGPILLPYQFR-----------MEEIEGFRYRCRDAM--RSVTKQAIREARL 447

Query: 762 -ELEEDMYKGGKADQQ-EERRRQKQMKVLKKELRH-LLSQPLFTESQKTKYPTQSGKPPL 818
            E++E++    K     E+  R  Q+      LRH L   P   +      P     P L
Sbjct: 448 KEIKEELLHSEKLKTYFEDNPRDLQL------LRHDLPLHPAVVKPHLGHVPDYLVPPAL 501

Query: 819 --LVSAPSKSESALSCLSKQKKKKTKKP 844
             LV    K +   S   K K+ K++ P
Sbjct: 502 RGLVRPHKKRKKLSSSCRKAKRAKSQNP 529



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 26/54 (48%), Positives = 37/54 (68%), Gaps = 1/54 (1%)

Query: 203 VLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPMIHAVL 256
           +L+A++ LG+S PT IQ   +  A+  K D+L  A TGSGKT A+AIPM+  +L
Sbjct: 18  LLQAVTDLGWSRPTLIQEKAIPLALEGK-DLLARARTGSGKTAAYAIPMLQLLL 70


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  121 bits (304), Expect = 2e-27
 Identities = 94/307 (30%), Positives = 157/307 (51%), Gaps = 33/307 (10%)

Query: 391 LVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRLWE 450
           LVLTPTRELA+QV+      + + G+++  + GG +  +Q   L +  +I++ATPGRL +
Sbjct: 320 LVLTPTRELALQVEGECCKYS-YKGLRSVCVYGGGNRDEQIEELKKGVDIIIATPGRLND 378

Query: 451 LIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQTLVFSATL 510
           L      +L+N+     LV+DEAD+M++ G   ++ ++L         P RQT++ SAT 
Sbjct: 379 LQMSNFVNLKNITY---LVLDEADKMLDMGFEPQIMKIL-----LDVRPDRQTVMTSATW 430

Query: 511 TLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTETKIHC 570
                      H  H  ++ ++   + ++  +G          T +   V ++ +  I  
Sbjct: 431 P----------HSVH--RLAQSYLKEPMIVYVG----------TLDLVAVSSVKQNIIVT 468

Query: 571 ETDEKDFYLYYFL--MQYPGRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQRLR 628
             +EK  ++  FL  M    + +VF +  +    LS  L + +I   +LH    Q+ R +
Sbjct: 469 TEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREK 528

Query: 629 NLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEGLSL 688
            LE F   +  +L+ATD+A+RGLD+  V HV ++  PR  E YVHR GRT RA   G+S+
Sbjct: 529 ALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSI 588

Query: 689 MLIGPED 695
             +   D
Sbjct: 589 TTLTRND 595



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 64/275 (23%), Positives = 108/275 (39%), Gaps = 60/275 (21%)

Query: 27  GKWKEVKIDPNMFADGQMDDLVCF---------------------EELTDYQLVSPAKNP 65
           G+W+     P   A G  +  +CF                     +  T+  +    + P
Sbjct: 49  GRWRGTSRPPEAVAAGHEELPLCFALKSHFVGAVIGRGGSKIKNIQSTTNTTIQIIQEQP 108

Query: 66  SSL---FSKEAPKRKAQAVSEEEEEEEGKSSSPKKKIKLKKSKNVATEGTSTQKEFEVKD 122
            SL   F  +A + KA+AV +   ++  ++ + +  I      +V  +G++         
Sbjct: 109 ESLVKIFGSKAMQTKAKAVIDNFVKKLEENYNSECGIDTAFQPSVGKDGSTDNNVVAGDR 168

Query: 123 PELEAQGDDMVCDDPEAGEMTSENLVQTAPKKKKNKGKKGLEPSQSTAAKVPKKAKTWIP 182
           P ++    D +    E G    +      P  KKN  K+    S +T+A    +A +W  
Sbjct: 169 PLIDW---DQI---REEGLKWQKTKWADLPPIKKNFYKE----STATSAMSKVEADSWRK 218

Query: 183 EVHDQKADVSAWKDLF------VPRP-------------VLRALSFLGFSAPTPIQALTL 223
           E  +       W DL       +P P             V+  +   GF  PTPIQ+   
Sbjct: 219 ENFN-----ITWDDLKDGEKRPIPNPTCTFDDAFQCYPEVMENIKKAGFQKPTPIQSQAW 273

Query: 224 APAIRDKLDILGAAETGSGKTLAFAIP-MIHAVLQ 257
            P +   +D++G A+TG+GKTL + +P  IH VLQ
Sbjct: 274 -PIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQ 307


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score =  119 bits (299), Expect = 9e-27
 Identities = 99/340 (29%), Positives = 160/340 (47%), Gaps = 52/340 (15%)

Query: 391 LVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRLWE 450
           ++L PTRELA Q+++      +  GI+T  ++GG+S + Q   L    EIV+ATPGRL +
Sbjct: 472 IILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLID 531

Query: 451 LIKEKHYHLRNLRQLRC--LVVDEADRMVEKGHFAELSQLLEMLNDSQYNPK-------- 500
           +++ ++  L      RC  +V+DEADRM++ G   ++ ++LE +  S   P         
Sbjct: 532 VLENRYLVLS-----RCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPE 586

Query: 501 -------------RQTLVFSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGK 547
                        RQT++F+AT+    +  AR   ++              +  IG  GK
Sbjct: 587 KMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPA------------VVYIGSAGK 634

Query: 548 PKVIDLTRNEATVETLTETKIHCETDEKDFYLYYFLMQ-YPGRSLVFANSISCIKRLSGL 606
           P      R E  V  ++E+       EK   L   L Q +    ++F N       L+  
Sbjct: 635 PH----ERVEQKVFLMSES-------EKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKS 683

Query: 607 LKVLDIMPLTLHACMHQKQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPR 666
           L+ +     TLH    Q+QR   L         +L+ATDVA RG+DI  V  V++Y + +
Sbjct: 684 LEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAK 743

Query: 667 TSEIYVHRSGRTARATNEGLSLMLIGPEDVINFKKIYKTL 706
             E Y+HR GRT RA   G+++  +  ED   F ++ + +
Sbjct: 744 NIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAI 783



 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 26/62 (41%), Positives = 40/62 (64%), Gaps = 1/62 (1%)

Query: 191 VSAWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIP 250
           + +WKD  +P  +L  +   G+  PTPIQ   +   ++++ DI+G AETGSGKT AF IP
Sbjct: 390 IRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNR-DIIGVAETGSGKTAAFLIP 448

Query: 251 MI 252
           ++
Sbjct: 449 LL 450


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score =  118 bits (295), Expect = 3e-26
 Identities = 100/321 (31%), Positives = 153/321 (47%), Gaps = 39/321 (12%)

Query: 381 KAYPKRPLLGLVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEI 440
           K YP    + LVL PTRELAVQ+ +     +  + ++  ++ GG    +Q R L R   +
Sbjct: 264 KQYP----ISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHL 319

Query: 441 VVATPGRLWELIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPK 500
           +VATPGRL ++++        L   + LV+DEADRM++ G   ++ +++E        PK
Sbjct: 320 LVATPGRLVDMMERGKI---GLDFCKYLVLDEADRMLDMGFEPQIRRIVEQ---DTMPPK 373

Query: 501 --RQTLVFSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEA 558
             R T++FSAT     Q  AR                D L + I        + + R  +
Sbjct: 374 GVRHTMMFSATFPKEIQMLAR----------------DFLDEYI-------FLAVGRVGS 410

Query: 559 TVETLTETKIHCETDEKDFYLYYFLMQYPGR---SLVFANSISCIKRLSGLLKVLDIMPL 615
           T E +T+  +  E  +K  +L   L+   G+   +LVF  +      L   L        
Sbjct: 411 TSENITQKVVWVEESDKRSFLLD-LLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACT 469

Query: 616 TLHACMHQKQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRS 675
           ++H    Q+ R   L QF   +  +L+AT VAARGLDI  V+HVI++ +P   E YVHR 
Sbjct: 470 SIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRI 529

Query: 676 GRTARATNEGLSLMLIGPEDV 696
           GRT R  N GL+       ++
Sbjct: 530 GRTGRVGNLGLATSFFNERNI 550



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 19/65 (29%), Positives = 40/65 (61%), Gaps = 1/65 (1%)

Query: 191 VSAWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIP 250
           + ++ D+ +   ++  +    ++ PTP+Q   + P I++K D++  A+TGSGKT AF +P
Sbjct: 179 IESFSDVEMGEIIMGNIELTRYTRPTPVQKHAI-PIIKEKRDLMACAQTGSGKTAAFLLP 237

Query: 251 MIHAV 255
           ++  +
Sbjct: 238 ILSQI 242


>gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1
           [Homo sapiens]
          Length = 851

 Score =  118 bits (295), Expect = 3e-26
 Identities = 101/340 (29%), Positives = 157/340 (46%), Gaps = 47/340 (13%)

Query: 391 LVLTPTRELAVQVKQHIDAVAR-FTGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRLW 449
           LVL PTRELA+Q    +  + + FT I   +L+GG   + ++  L +   I+++TPGRL 
Sbjct: 309 LVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLV 368

Query: 450 ELIKE-KHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQTLVFSA 508
           + IK  K+ H     +LR LV DEADR+++ G   +++ +L  +N      KRQ ++ SA
Sbjct: 369 DHIKSTKNIHFS---RLRWLVFDEADRILDLGFEKDITVILNAVNAECQ--KRQNVLLSA 423

Query: 509 TLT----------LVHQAPARILHKKHTKKMDKTA------------KLDLLMQKIGMRG 546
           TLT          L       +L K H +   K              KLD       ++ 
Sbjct: 424 TLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQ 483

Query: 547 KPKVIDLTRNEATVETLTETKIHCETDEK-----------DFYLYYFLMQYPGRSLVFAN 595
              V+        +      K   E D+K           +F+   FL     ++L+ ++
Sbjct: 484 HVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFL-----QTLLSSS 538

Query: 596 SISCIKRLSGLLKVLDIMPLTLHACMHQKQRLRNLEQFARLEDCVLLATDVAARGLDIPK 655
                 +L      L    L LH  M Q++R    ++F+     VLL TDVAARGLD+P+
Sbjct: 539 GAPASGQLPSASMRLKF--LRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQ 596

Query: 656 VQHVIHYQVPRTSEIYVHRSGRTARATNEGLSLMLIGPED 695
           V  ++ Y  P +   Y+HR GRTAR    G SL+++ P +
Sbjct: 597 VTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSE 636



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 43/187 (22%), Positives = 82/187 (43%), Gaps = 29/187 (15%)

Query: 72  EAPKRKAQAVSEEEEEEEGKSSS--PKKKIKLKKSKNVATEGTSTQKEFEVKDPELEAQG 129
           +A KRK QA SE    +    +S  P KK  +K+++   T   + QK F  K   +    
Sbjct: 133 KATKRKYQASSEAPPAKRRNETSFLPAKKTSVKETQR--TFKGNAQKMFSPKKHSVSTSD 190

Query: 130 DDMVCDDPEAGEMTSENLVQTAPKKKKNKGKKGLEPSQSTAAKVPKKAKTWIPEVHDQKA 189
            +                ++T+   K N               +P+  +  + +V ++  
Sbjct: 191 RNQ----------EERQCIKTSSLFKNNPD-------------IPELHRPVVKQVQEKVF 227

Query: 190 DVSAWKDLFV-PRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFA 248
             +A+ +L + P  +    + L  S+ T +Q  ++ P + +  D L  ++TGSGKTLA+ 
Sbjct: 228 TSAAFHELGLHPHLISTINTVLKMSSMTSVQKQSI-PVLLEGRDALVRSQTGSGKTLAYC 286

Query: 249 IPMIHAV 255
           IP++ ++
Sbjct: 287 IPVVQSL 293


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  115 bits (289), Expect = 1e-25
 Identities = 100/311 (32%), Positives = 148/311 (47%), Gaps = 37/311 (11%)

Query: 381 KAYPKRPLLGLVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEI 440
           K YP    + LVL PTRELAVQ+ +     +  + ++  ++ GG    +Q R L R   +
Sbjct: 262 KQYP----ISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHL 317

Query: 441 VVATPGRLWELIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPK 500
           +VATPGRL ++++        L   + LV+DEADRM++ G   ++ +++E        PK
Sbjct: 318 LVATPGRLVDMMERGKI---GLDFCKYLVLDEADRMLDMGFEPQIRRIVEQ---DTMPPK 371

Query: 501 --RQTLVFSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEA 558
             R T++FSAT     Q  AR                D L + I        + + R  +
Sbjct: 372 GVRHTMMFSATFPKEIQMLAR----------------DFLDEYI-------FLAVGRVGS 408

Query: 559 TVETLTETKIHCETDEKDFYLYYFLMQYPGRSL--VFANSISCIKRLSGLLKVLDIMPLT 616
           T E +T+  +  E  +K  +L   L      SL  VF  +      L   L        +
Sbjct: 409 TSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTS 468

Query: 617 LHACMHQKQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSG 676
           +H    Q+ R   L QF   +  +L+AT VAARGLDI  V+HVI++ +P   E YVHR G
Sbjct: 469 IHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIG 528

Query: 677 RTARATNEGLS 687
           RT R  N GL+
Sbjct: 529 RTGRVGNLGLA 539



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 19/65 (29%), Positives = 38/65 (58%), Gaps = 1/65 (1%)

Query: 191 VSAWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIP 250
           +  + D+ +   ++  +    ++ PTP+Q   + P I+ K D++  A+TGSGKT AF +P
Sbjct: 177 IENFSDIDMGEIIMGNIELTRYTRPTPVQKHAI-PIIKGKRDLMACAQTGSGKTAAFLLP 235

Query: 251 MIHAV 255
           ++  +
Sbjct: 236 ILSQI 240


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  115 bits (289), Expect = 1e-25
 Identities = 100/311 (32%), Positives = 148/311 (47%), Gaps = 37/311 (11%)

Query: 381 KAYPKRPLLGLVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEI 440
           K YP    + LVL PTRELAVQ+ +     +  + ++  ++ GG    +Q R L R   +
Sbjct: 262 KQYP----ISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHL 317

Query: 441 VVATPGRLWELIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPK 500
           +VATPGRL ++++        L   + LV+DEADRM++ G   ++ +++E        PK
Sbjct: 318 LVATPGRLVDMMERGKI---GLDFCKYLVLDEADRMLDMGFEPQIRRIVEQ---DTMPPK 371

Query: 501 --RQTLVFSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEA 558
             R T++FSAT     Q  AR                D L + I        + + R  +
Sbjct: 372 GVRHTMMFSATFPKEIQMLAR----------------DFLDEYI-------FLAVGRVGS 408

Query: 559 TVETLTETKIHCETDEKDFYLYYFLMQYPGRSL--VFANSISCIKRLSGLLKVLDIMPLT 616
           T E +T+  +  E  +K  +L   L      SL  VF  +      L   L        +
Sbjct: 409 TSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTS 468

Query: 617 LHACMHQKQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSG 676
           +H    Q+ R   L QF   +  +L+AT VAARGLDI  V+HVI++ +P   E YVHR G
Sbjct: 469 IHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIG 528

Query: 677 RTARATNEGLS 687
           RT R  N GL+
Sbjct: 529 RTGRVGNLGLA 539



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 19/65 (29%), Positives = 38/65 (58%), Gaps = 1/65 (1%)

Query: 191 VSAWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIP 250
           +  + D+ +   ++  +    ++ PTP+Q   + P I+ K D++  A+TGSGKT AF +P
Sbjct: 177 IENFSDIDMGEIIMGNIELTRYTRPTPVQKHAI-PIIKGKRDLMACAQTGSGKTAAFLLP 235

Query: 251 MIHAV 255
           ++  +
Sbjct: 236 ILSQI 240


>gi|8922976 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 [Homo sapiens]
          Length = 540

 Score =  115 bits (288), Expect = 2e-25
 Identities = 100/340 (29%), Positives = 162/340 (47%), Gaps = 35/340 (10%)

Query: 390 GLVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRP--EIVVATPGR 447
           GLVL P+RELA QV+     + R  G+    L GG   ++ +  L+R+P  +++VATPG 
Sbjct: 206 GLVLVPSRELAQQVRAVAQPLGRSLGLLVRDLEGGHGMRRIRLQLSRQPSADVLVATPGA 265

Query: 448 LWELIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLN--------DSQYNP 499
           LW+ +K +   L +L QL  LV+DEAD ++++     +  +LE  +        +  +NP
Sbjct: 266 LWKALKSR---LISLEQLSFLVLDEADTLLDESFLELVDYILEKSHIAEGPADLEDPFNP 322

Query: 500 KRQTLVFSATLTLVHQAPARILHKKHTKKMDKT---AKLDLLMQKIGMRGKPKVIDLTRN 556
           K Q ++  AT     +   ++L+K  +     T   +KL  +M  +    K   + L   
Sbjct: 323 KAQLVLVGATFP---EGVGQLLNKVASPDAVTTITSSKLHCIMPHV----KQTFLRLKGA 375

Query: 557 EATVETLTETKIHCETDEKDFYLYYFLMQYPGRSLVFANSISCIKRLSGLLKVLDIMPLT 616
           +   E +   K H +  E+            G  LVF NS S +  L  +L    I  L 
Sbjct: 376 DKVAELVHILK-HRDRAER--------TGPSGTVLVFCNSSSTVNWLGYILDDHKIQHLR 426

Query: 617 LHACMHQKQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSG 676
           L   M    R+   + F +    +LL TD+A+RGLD   V+ V++Y  P T + Y+HR+G
Sbjct: 427 LQGQMPALMRVGIFQSFQKSSRDILLCTDIASRGLDSTGVELVVNYDFPPTLQDYIHRAG 486

Query: 677 RTARATNE--GLSLMLI-GPEDVINFKKIYKTLKKDEDIP 713
           R  R  +E  G  +  +  P DV   +KI    ++   +P
Sbjct: 487 RVGRVGSEVPGTVISFVTHPWDVSLVQKIELAARRRRSLP 526



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 19/54 (35%), Positives = 35/54 (64%), Gaps = 1/54 (1%)

Query: 215 PTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPMIHAVLQWQKRNAAPPPS 268
           PT +Q+ T+   +R +  ++ AAETGSGKTL++ +P++  +L     ++ P P+
Sbjct: 151 PTTVQSSTIPSLLRGR-HVVCAAETGSGKTLSYLLPLLQRLLGQPSLDSLPIPA 203


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score =  115 bits (288), Expect = 2e-25
 Identities = 88/308 (28%), Positives = 157/308 (50%), Gaps = 34/308 (11%)

Query: 391 LVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQ-QRMLNRRPEIVVATPGRLW 449
           LVL PTRELA Q+++ I A+  + G      +GG + + + Q++    P IVV TPGR++
Sbjct: 105 LVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVF 164

Query: 450 ELIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQTLVFSAT 509
           +++  ++    + + ++  V+DEAD M+ +G   ++ ++ + LN S      Q ++ SAT
Sbjct: 165 DMLNRRYL---SPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSI-----QVVLLSAT 216

Query: 510 LTLVHQAPARILHKKHTKK-MDKTAKLDLLMQKIGMRG-KPKVIDLTRNEATVETLTETK 567
           +      P  +L    TKK M    ++ +  +++ + G K   I++ R E  ++TL    
Sbjct: 217 M------PTDVLEV--TKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLC--- 265

Query: 568 IHCETDEKDFYLYYFLMQYPGRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQRL 627
                   D Y    + Q    +++F N+   +  L+  +   D     LH  M QK+R 
Sbjct: 266 --------DLYETLTITQ----AVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERD 313

Query: 628 RNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEGLS 687
             + +F      VL+ TD+ ARG+D+ +V  VI+Y +P   E Y+HR GR  R   +G++
Sbjct: 314 VIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVA 373

Query: 688 LMLIGPED 695
           +  +  ED
Sbjct: 374 INFVTEED 381



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 20/62 (32%), Positives = 35/62 (56%), Gaps = 1/62 (1%)

Query: 191 VSAWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIP 250
           V  + D+ +   +LR +   GF  P+ IQ   + P I+   D++  A++G+GKT  FAI 
Sbjct: 32  VDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKG-YDVIAQAQSGTGKTATFAIS 90

Query: 251 MI 252
           ++
Sbjct: 91  IL 92


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score =  115 bits (287), Expect = 2e-25
 Identities = 90/334 (26%), Positives = 166/334 (49%), Gaps = 47/334 (14%)

Query: 391 LVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQ-QRMLNRRPEIVVATPGRLW 449
           LVL PTRELA Q+++ + A+  + G      +GG + + + Q++    P I+V TPGR++
Sbjct: 104 LVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVF 163

Query: 450 ELIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKRQTLVFSAT 509
           +++  ++    + + ++  V+DEAD M+ +G   ++  + + LN +      Q ++ SAT
Sbjct: 164 DMLNRRYL---SPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNT-----QVVLLSAT 215

Query: 510 LTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTETKIH 569
           +      P+ +L    TKK               MR   +++ + + E T+E + +  I+
Sbjct: 216 M------PSDVLEV--TKKF--------------MRDPIRIL-VKKEELTLEGIRQFYIN 252

Query: 570 CETDEK------DFYLYYFLMQYPGRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQ 623
            E +E       D Y    + Q    +++F N+   +  L+  +   D     +H  M Q
Sbjct: 253 VEREEWKLDTLCDLYETLTITQ----AVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQ 308

Query: 624 KQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATN 683
           K+R   + +F      VL+ TD+ ARG+D+ +V  VI+Y +P   E Y+HR GR  R   
Sbjct: 309 KERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGR 368

Query: 684 EGLSLMLIGPEDVINFKKI---YKTLKKDEDIPL 714
           +G+++ ++  ED    + I   Y T    E++PL
Sbjct: 369 KGVAINMVTEEDKRTLRDIETFYNT--SIEEMPL 400



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 1/65 (1%)

Query: 191 VSAWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIP 250
           V ++ D+ +   +LR +   GF  P+ IQ   + P I+   D++  A++G+GKT  FAI 
Sbjct: 31  VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKG-YDVIAQAQSGTGKTATFAIS 89

Query: 251 MIHAV 255
           ++  +
Sbjct: 90  ILQQI 94


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score =  113 bits (282), Expect = 9e-25
 Identities = 95/310 (30%), Positives = 145/310 (46%), Gaps = 33/310 (10%)

Query: 391 LVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRLWE 450
           LVL PTRELA QV +    + R   +  A   GG S Q Q   +    +I+V TPGR+ +
Sbjct: 215 LVLAPTRELANQVAKDFKDITR--KLSVACFYGGTSYQSQINHIRNGIDILVGTPGRIKD 272

Query: 451 LIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLE--MLNDSQYNPKRQTLVFSA 508
            ++     L  LR +   V+DE D+M++ G   ++  ++      DS+ NP  QTL+FSA
Sbjct: 273 HLQSGRLDLSKLRHV---VLDEVDQMLDLGFAEQVEDIIHESYKTDSEDNP--QTLLFSA 327

Query: 509 TLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTETKI 568
           T        A+   K   +++D   K+                  T+  AT  T+    I
Sbjct: 328 TCPQWVYKVAKKYMKSRYEQVDLVGKM------------------TQKAAT--TVEHLAI 367

Query: 569 HCETDEKDFYLYYFLMQYPG---RSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQ 625
            C   ++   +   L  Y G   R+++F  +   +  ++ +   +      LH  + Q Q
Sbjct: 368 QCHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMA-MNPHIKQNAQCLHGDIAQSQ 426

Query: 626 RLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEG 685
           R   L+ F      VL+AT+VAARGLDIP+V  VI    P+  E Y+HRSGRT RA   G
Sbjct: 427 REITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTG 486

Query: 686 LSLMLIGPED 695
           + +    P +
Sbjct: 487 ICICFYQPRE 496



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 36/186 (19%), Positives = 75/186 (40%), Gaps = 8/186 (4%)

Query: 82  SEEEEEEEGKSSSPKKKIKLKKSKNVATEGTSTQKEFEVKDPELEAQGDDMVCDDPEAGE 141
           SE +++E  KS   K +      +   T       + +    +     + +  D  E   
Sbjct: 20  SESQKKERQKSDRRKSRHHYDSDEKSETRENGVTDDLDAPKAKKSKMKEKLNGDTEEGFN 79

Query: 142 MTSENLVQTAPKKKKNKGKKGLEPSQSTAAKVP-------KKAKTWIPEVHDQKADVSAW 194
             S+   ++   ++K+     ++  +  + +V        K +   + E   ++    A+
Sbjct: 80  RLSDEFSKSHKSRRKDLPNGDIDEYEKKSKRVSSLDTSTHKSSDNKLEETLTREQKEGAF 139

Query: 195 KDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPMIHA 254
            +  +    ++ L   G +   PIQ  T  P    K D++  A TG+GKT +FAIP+I  
Sbjct: 140 SNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGK-DLIAQARTGTGKTFSFAIPLIER 198

Query: 255 VLQWQK 260
           + + Q+
Sbjct: 199 LQRNQE 204


>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
           sapiens]
          Length = 427

 Score =  112 bits (280), Expect = 1e-24
 Identities = 82/314 (26%), Positives = 156/314 (49%), Gaps = 44/314 (14%)

Query: 391 LVLTPTRELAVQVKQHIDAVARFT-GIKTAILVGGMSTQKQQRMLNRR-PEIVVATPGRL 448
           LV+  TRELA Q+ +  +  +++   +K ++  GG+S +K + +L +  P +VV TPGR+
Sbjct: 116 LVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCPHVVVGTPGRI 175

Query: 449 WELIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQ----YNP-KRQT 503
             L++ + + L+N++     V+DE D+M+E+         L+M  D Q      P ++Q 
Sbjct: 176 LALVRNRSFSLKNVKHF---VLDECDKMLEQ---------LDMRRDVQEIFRLTPHEKQC 223

Query: 504 LVFSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETL 563
           ++FSATL+   +   R                        M+   +V      + T+  L
Sbjct: 224 MMFSATLSKDIRPVCRKF----------------------MQDPMEVFVDDETKLTLHGL 261

Query: 564 TETKIHCETDEKDFYLYYFL--MQYPGRSLVFANSISCIKRLSGLLKVLDIMPLTLHACM 621
            +  +  +  EK+  L+  L  +++  + ++F  S+     L+ LL   +   + +H  M
Sbjct: 262 QQYYVKLKDSEKNRKLFDLLDVLEF-NQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGM 320

Query: 622 HQKQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARA 681
            Q++RL   +QF   +  +L+AT++  RG+DI +V  V +Y +P  S+ Y+HR  R  R 
Sbjct: 321 AQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRF 380

Query: 682 TNEGLSLMLIGPED 695
             +GL++  +  E+
Sbjct: 381 GTKGLAITFVSDEN 394



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 6/91 (6%)

Query: 165 PSQSTAAKVPKKAKTWIPEVHDQKADVSAWKDLFVPRPVLRALSFLGFSAPTPIQALTLA 224
           P +ST A   K  K     +H      S ++D  +   +LRA+   GF  P+ +Q   + 
Sbjct: 22  PQESTPAPPKKDIKGSYVSIHS-----SGFRDFLLKPELLRAIVDCGFEHPSEVQHECIP 76

Query: 225 PAIRDKLDILGAAETGSGKTLAFAIPMIHAV 255
            AI   +D+L  A++G GKT  F +  +  +
Sbjct: 77  QAILG-MDVLCQAKSGMGKTAVFVLATLQQI 106


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,496,377
Number of Sequences: 37866
Number of extensions: 1684042
Number of successful extensions: 11921
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 119
Number of HSP's successfully gapped in prelim test: 315
Number of HSP's that attempted gapping in prelim test: 10185
Number of HSP's gapped (non-prelim): 1693
length of query: 859
length of database: 18,247,518
effective HSP length: 111
effective length of query: 748
effective length of database: 14,044,392
effective search space: 10505205216
effective search space used: 10505205216
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.