Search of human proteins with 9966761

Search of human proteins with 9966761

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9966761 choroideremia isoform a [Homo sapiens]
         (653 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9966761 choroideremia isoform a [Homo sapiens]                    1315   0.0  
gi|53832014 choroideremia-like Rab escort protein 2 [Homo sapiens]    943   0.0  
gi|224028271 choroideremia isoform b [Homo sapiens]                   213   4e-55
gi|4503971 GDP dissociation inhibitor 1 [Homo sapiens]                110   4e-24
gi|6598323 GDP dissociation inhibitor 2 isoform 1 [Homo sapiens]      110   4e-24
gi|169646441 GDP dissociation inhibitor 2 isoform 2 [Homo sapiens]     69   1e-11
gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens]    38   0.026
gi|13654239 WW domain containing E3 ubiquitin protein ligase 1 [...    33   0.63 
gi|163310725 ER degradation enhancer, mannosidase alpha-like 3 [...    32   1.4  
gi|194097489 RAN binding protein 3 isoform RANBP3-b [Homo sapiens]     32   2.4  
gi|194097487 RAN binding protein 3 isoform RANBP3-a [Homo sapiens]     32   2.4  
gi|6466466 RAN binding protein 3 isoform RANBP3-d [Homo sapiens]       32   2.4  
gi|238550202 tubby like protein 3 isoform 2 [Homo sapiens]             31   3.1  
gi|21536436 tubby like protein 3 isoform 1 [Homo sapiens]              31   3.1  
gi|52630429 nuclear factor, interleukin 3 regulated [Homo sapiens]     31   4.1  
gi|7662088 Rho guanine nucleotide exchange factor (GEF) 12 [Homo...    31   4.1  
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    30   5.4  
gi|160420295 hypothetical protein LOC85459 [Homo sapiens]              30   5.4  
gi|41393608 reticulon 3 isoform b [Homo sapiens]                       30   7.0  
gi|239757925 PREDICTED: similar to melanoma antigen family C, 2 ...    30   7.0  
gi|239754799 PREDICTED: similar to hCG1797215 [Homo sapiens]           30   7.0  
gi|239752435 PREDICTED: similar to melanoma antigen family C, 2 ...    30   7.0  
gi|239749323 PREDICTED: similar to hCG1797215 [Homo sapiens]           30   7.0  
gi|239746952 PREDICTED: similar to melanoma antigen family C, 2 ...    30   7.0  
gi|239743413 PREDICTED: hypothetical protein XP_002342849 [Homo ...    30   7.0  
gi|239509120 PREDICTED: similar to hCG1797215 [Homo sapiens]           30   7.0  
gi|217330641 IWS1 homolog [Homo sapiens]                               30   7.0  
gi|11545835 TSPY-like 2 [Homo sapiens]                                 30   7.0  
gi|4758274 erythrocyte membrane protein band 4.1 (elliptocytosis...    30   9.1  
gi|187936949 solute carrier family 39 (zinc transporter), member...    30   9.1  

>gi|9966761 choroideremia isoform a [Homo sapiens]
          Length = 653

 Score = 1315 bits (3404), Expect = 0.0
 Identities = 653/653 (100%), Positives = 653/653 (100%)

Query: 1   MADTLPSEFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFSFSGLLSWLK 60
           MADTLPSEFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFSFSGLLSWLK
Sbjct: 1   MADTLPSEFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFSFSGLLSWLK 60

Query: 61  EYQENSDIVSDSPVWQDQILENEEAIALSRKDKTIQHVEVFCYASQDLHEDVEEAGALQK 120
           EYQENSDIVSDSPVWQDQILENEEAIALSRKDKTIQHVEVFCYASQDLHEDVEEAGALQK
Sbjct: 61  EYQENSDIVSDSPVWQDQILENEEAIALSRKDKTIQHVEVFCYASQDLHEDVEEAGALQK 120

Query: 121 NHALVTSANSTEAADSAFLPTEDESLSTMSCEMLTEQTPSSDPENALEVNGAEVTGEKEN 180
           NHALVTSANSTEAADSAFLPTEDESLSTMSCEMLTEQTPSSDPENALEVNGAEVTGEKEN
Sbjct: 121 NHALVTSANSTEAADSAFLPTEDESLSTMSCEMLTEQTPSSDPENALEVNGAEVTGEKEN 180

Query: 181 HCDDKTCVPSTSAEDMSENVPIAEDTTEQPKKNRITYSQIIKEGRRFNIDLVSKLLYSRG 240
           HCDDKTCVPSTSAEDMSENVPIAEDTTEQPKKNRITYSQIIKEGRRFNIDLVSKLLYSRG
Sbjct: 181 HCDDKTCVPSTSAEDMSENVPIAEDTTEQPKKNRITYSQIIKEGRRFNIDLVSKLLYSRG 240

Query: 241 LLIDLLIKSNVSRYAEFKNITRILAFREGRVEQVPCSRADVFNSKQLTMVEKRMLMKFLT 300
           LLIDLLIKSNVSRYAEFKNITRILAFREGRVEQVPCSRADVFNSKQLTMVEKRMLMKFLT
Sbjct: 241 LLIDLLIKSNVSRYAEFKNITRILAFREGRVEQVPCSRADVFNSKQLTMVEKRMLMKFLT 300

Query: 301 FCMEYEKYPDEYKGYEEITFYEYLKTQKLTPNLQYIVMHSIAMTSETASSTIDGLKATKN 360
           FCMEYEKYPDEYKGYEEITFYEYLKTQKLTPNLQYIVMHSIAMTSETASSTIDGLKATKN
Sbjct: 301 FCMEYEKYPDEYKGYEEITFYEYLKTQKLTPNLQYIVMHSIAMTSETASSTIDGLKATKN 360

Query: 361 FLHCLGRYGNTPFLFPLYGQGELPQCFCRMCAVFGGIYCLRHSVQCLVVDKESRKCKAII 420
           FLHCLGRYGNTPFLFPLYGQGELPQCFCRMCAVFGGIYCLRHSVQCLVVDKESRKCKAII
Sbjct: 361 FLHCLGRYGNTPFLFPLYGQGELPQCFCRMCAVFGGIYCLRHSVQCLVVDKESRKCKAII 420

Query: 421 DQFGQRIISEHFLVEDSYFPENMCSRVQYRQISRAVLITDRSVLKTDSDQQISILTVPAE 480
           DQFGQRIISEHFLVEDSYFPENMCSRVQYRQISRAVLITDRSVLKTDSDQQISILTVPAE
Sbjct: 421 DQFGQRIISEHFLVEDSYFPENMCSRVQYRQISRAVLITDRSVLKTDSDQQISILTVPAE 480

Query: 481 EPGTFAVRVIELCSSTMTCMKGTYLVHLTCTSSKTAREDLESVVQKLFVPYTEMEIENEQ 540
           EPGTFAVRVIELCSSTMTCMKGTYLVHLTCTSSKTAREDLESVVQKLFVPYTEMEIENEQ
Sbjct: 481 EPGTFAVRVIELCSSTMTCMKGTYLVHLTCTSSKTAREDLESVVQKLFVPYTEMEIENEQ 540

Query: 541 VEKPRILWALYFNMRDSSDISRSCYNDLPSNVYVCSGPDCGLGNDNAVKQAETLFQEICP 600
           VEKPRILWALYFNMRDSSDISRSCYNDLPSNVYVCSGPDCGLGNDNAVKQAETLFQEICP
Sbjct: 541 VEKPRILWALYFNMRDSSDISRSCYNDLPSNVYVCSGPDCGLGNDNAVKQAETLFQEICP 600

Query: 601 NEDFCPPPPNPEDIILDGDSLQPEASESSAIPEANSETFKESTNLGNLEESSE 653
           NEDFCPPPPNPEDIILDGDSLQPEASESSAIPEANSETFKESTNLGNLEESSE
Sbjct: 601 NEDFCPPPPNPEDIILDGDSLQPEASESSAIPEANSETFKESTNLGNLEESSE 653


>gi|53832014 choroideremia-like Rab escort protein 2 [Homo sapiens]
          Length = 656

 Score =  943 bits (2438), Expect = 0.0
 Identities = 470/653 (71%), Positives = 541/653 (82%), Gaps = 4/653 (0%)

Query: 1   MADTLPSEFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFSFSGLLSWLK 60
           MAD LP+EFDV++IGTGLPESI+AAACSRSG+RVLH+DSRSYYGGNWASFSFSGLLSWLK
Sbjct: 1   MADNLPTEFDVVIIGTGLPESILAAACSRSGQRVLHIDSRSYYGGNWASFSFSGLLSWLK 60

Query: 61  EYQENSDIVSDSPV-WQDQILENEEAIALSRKDKTIQHVEVFCYASQDLHEDVEEAGALQ 119
           EYQ+N+DI  +S V WQD I E EEAI L +KD+TIQH E FCYASQD+ ++VEE GALQ
Sbjct: 61  EYQQNNDIGEESTVVWQDLIHETEEAITLRKKDETIQHTEAFCYASQDMEDNVEEIGALQ 120

Query: 120 KNHALVTSANSTEAADSAFLPTEDESLSTMSCEMLTEQTPSSDPENALEVNGAEVTGEKE 179
           KN +L  S   TE  DSA LP E +     S EM  + T  SD E +LEV   E + EKE
Sbjct: 121 KNPSLGVSNTFTEVLDSA-LPEESQLSYFNSDEMPAKHTQKSDTEISLEVTDVEESVEKE 179

Query: 180 NHCDDKTCVPSTSAED--MSENVPIAEDTTEQPKKNRITYSQIIKEGRRFNIDLVSKLLY 237
            +C DKTC+ + S +D    E+    ED  ++P +NRITYSQI+KEGRRFNIDLVSKLLY
Sbjct: 180 KYCGDKTCMHTVSDKDGDKDESKSTVEDKADEPIRNRITYSQIVKEGRRFNIDLVSKLLY 239

Query: 238 SRGLLIDLLIKSNVSRYAEFKNITRILAFREGRVEQVPCSRADVFNSKQLTMVEKRMLMK 297
           S+GLLIDLLIKS+VSRY EFKN+TRILAFREG+VEQVPCSRADVFNSK+LTMVEKRMLMK
Sbjct: 240 SQGLLIDLLIKSDVSRYVEFKNVTRILAFREGKVEQVPCSRADVFNSKELTMVEKRMLMK 299

Query: 298 FLTFCMEYEKYPDEYKGYEEITFYEYLKTQKLTPNLQYIVMHSIAMTSETASSTIDGLKA 357
           FLTFC+EYE++PDEY+ + + +F EYLKT+KLTPNLQ+ V+HSIAMTSE++ +TIDGL A
Sbjct: 300 FLTFCLEYEQHPDEYQAFRQCSFSEYLKTKKLTPNLQHFVLHSIAMTSESSCTTIDGLNA 359

Query: 358 TKNFLHCLGRYGNTPFLFPLYGQGELPQCFCRMCAVFGGIYCLRHSVQCLVVDKESRKCK 417
           TKNFL CLGR+GNTPFLFPLYGQGE+PQ FCRMCAVFGGIYCLRH VQC VVDKES +CK
Sbjct: 360 TKNFLQCLGRFGNTPFLFPLYGQGEIPQGFCRMCAVFGGIYCLRHKVQCFVVDKESGRCK 419

Query: 418 AIIDQFGQRIISEHFLVEDSYFPENMCSRVQYRQISRAVLITDRSVLKTDSDQQISILTV 477
           AIID FGQRI +++F+VEDSY  E  CS VQY+QISRAVLITD+S+LKTD DQQ SIL V
Sbjct: 420 AIIDHFGQRINAKYFIVEDSYLSEETCSNVQYKQISRAVLITDQSILKTDLDQQTSILIV 479

Query: 478 PAEEPGTFAVRVIELCSSTMTCMKGTYLVHLTCTSSKTAREDLESVVQKLFVPYTEMEIE 537
           P  EPG  AVRV ELCSSTMTCMK TYLVHLTC+SSKTAREDLESVV+KLF PYTE EI 
Sbjct: 480 PPAEPGACAVRVTELCSSTMTCMKDTYLVHLTCSSSKTAREDLESVVKKLFTPYTETEIN 539

Query: 538 NEQVEKPRILWALYFNMRDSSDISRSCYNDLPSNVYVCSGPDCGLGNDNAVKQAETLFQE 597
            E++ KPR+LWALYFNMRDSS ISRS YN LPSNVYVCSGPDCGLGN++AVKQAETLFQE
Sbjct: 540 EEELTKPRLLWALYFNMRDSSGISRSSYNGLPSNVYVCSGPDCGLGNEHAVKQAETLFQE 599

Query: 598 ICPNEDFCPPPPNPEDIILDGDSLQPEASESSAIPEANSETFKESTNLGNLEE 650
           I P E+FCPPPPNPEDII DGD  QPEA  ++ +  A  E+ +ES NL + E+
Sbjct: 600 IFPTEEFCPPPPNPEDIIFDGDDKQPEAPGTNNVVMAKLESSEESKNLESPEK 652


>gi|224028271 choroideremia isoform b [Homo sapiens]
          Length = 110

 Score =  213 bits (542), Expect = 4e-55
 Identities = 105/108 (97%), Positives = 105/108 (97%)

Query: 1   MADTLPSEFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFSFSGLLSWLK 60
           MADTLPSEFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFSFSGLLSWLK
Sbjct: 1   MADTLPSEFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFSFSGLLSWLK 60

Query: 61  EYQENSDIVSDSPVWQDQILENEEAIALSRKDKTIQHVEVFCYASQDL 108
           EYQENSDIVSDSPVWQDQILENEEAIALSRKDKTIQHVEVFCYA   L
Sbjct: 61  EYQENSDIVSDSPVWQDQILENEEAIALSRKDKTIQHVEVFCYARSTL 108


>gi|4503971 GDP dissociation inhibitor 1 [Homo sapiens]
          Length = 447

 Score =  110 bits (275), Expect = 4e-24
 Identities = 82/325 (25%), Positives = 151/325 (46%), Gaps = 21/325 (6%)

Query: 224 GRRFNIDLVSKLLYSRGLLIDLLIKSNVSRYAEFKNITRILAFREGRVEQVPCSRADVFN 283
           GR +N+DL+ K L + G L+ +L+ + V+RY +FK +     ++ G++ +VP +  +   
Sbjct: 69  GRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALA 128

Query: 284 SKQLTMVEKRMLMKFLTFCMEY-EKYPDEYKGYEEIT--FYEYLKTQKLTPNLQYIVMHS 340
           S  + M EKR   KFL F   + E  P  ++G +  T    +  +   L  ++     H+
Sbjct: 129 SNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQDVIDFTGHA 188

Query: 341 IAM---TSETASSTIDGLKATKNFLHCLGRYGNTPFLFPLYGQGELPQCFCRMCAVFGGI 397
           +A+           ++ +   K +   L RYG +P+L+PLYG GELPQ F R+ A++GG 
Sbjct: 189 LALYRTDDYLDQPCLETVNRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGT 248

Query: 398 YCLRHSVQCLVVDKESRKCKAIIDQFGQRIISEHFLVEDSYFPENMCSRVQYRQISRAVL 457
           Y L   V  +++  E+ K   +  + G+    +  + + SY P+ +    +  Q+ R + 
Sbjct: 249 YMLNKPVDDIIM--ENGKVVGVKSE-GEVARCKQLICDPSYIPDRV---RKAGQVIRIIC 302

Query: 458 ITDRSVLKTDSDQQISILTVPAEEPGTFAVRVIELCSSTMTCMKGTYLVHLTCTSSKT-- 515
           I    +  T+      I+    +      + V  +  +     +G Y+   + T   T  
Sbjct: 303 ILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETTDP 362

Query: 516 ------AREDLESVVQKLFVPYTEM 534
                 A E LE + QK FV  +++
Sbjct: 363 EKEVEPALELLEPIDQK-FVAISDL 386



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 22/47 (46%), Positives = 33/47 (70%)

Query: 5  LPSEFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFS 51
          +  E+DVIV+GTGL E I++   S +G++VLH+D   YYGG  +S +
Sbjct: 1  MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSIT 47


>gi|6598323 GDP dissociation inhibitor 2 isoform 1 [Homo sapiens]
          Length = 445

 Score =  110 bits (275), Expect = 4e-24
 Identities = 93/391 (23%), Positives = 172/391 (43%), Gaps = 40/391 (10%)

Query: 167 LEVNGAEVTGEKENHCDDKTCVPSTSAEDMSENVPIAEDTTEQPKKNRITYSQIIKEGRR 226
           + VNG +V     N          T  ED+ +   I     E            +  GR 
Sbjct: 23  MSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPES-----------MGRGRD 71

Query: 227 FNIDLVSKLLYSRGLLIDLLIKSNVSRYAEFKNITRILAFREGRVEQVPCSRADVFNSKQ 286
           +N+DL+ K L + G L+ +L+ + V+RY +FK       ++ G++ +VP + A+   S  
Sbjct: 72  WNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVTEGSFVYKGGKIYKVPSTEAEALASSL 131

Query: 287 LTMVEKRMLMKFLTFCMEY-EKYPDEYKGYE--EITFYEYLKTQKLTPNLQYIVMHSIAM 343
           + + EKR   KFL +   + EK P  ++G +  + T  +  K   L  ++     H++A+
Sbjct: 132 MGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALAL 191

Query: 344 ------TSETASSTIDGLKATKNFLHCLGRYGNTPFLFPLYGQGELPQCFCRMCAVFGGI 397
                   +    TI+ +K    +   L RYG +P+L+PLYG GELPQ F R+ A++GG 
Sbjct: 192 YRTDDYLDQPCYETINRIKL---YSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGT 248

Query: 398 YCLRHSVQCLVVDKESRKCKAI-IDQFGQRIISEHFLVEDSYFPENMCSRVQYRQISRAV 456
           Y L   ++ ++V    +  K I +   G+    +  + + SY  + +    +  Q+ R +
Sbjct: 249 YMLNKPIEEIIV----QNGKVIGVKSEGEIARCKQLICDPSYVKDRV---EKVGQVIRVI 301

Query: 457 LITDRSVLKTDSDQQISILTVPAEEPGTFAVRVIELCSSTMTCMKGTYLVHLTCT----- 511
            I    +  T+      I+    +      + V  +  +     +G Y+  ++ T     
Sbjct: 302 CILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKE 361

Query: 512 ---SSKTAREDLESVVQKLFVPYTEMEIENE 539
                + A E LE + QK FV  +++ +  +
Sbjct: 362 PEKEIRPALELLEPIEQK-FVSISDLLVPKD 391



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 23/44 (52%), Positives = 32/44 (72%)

Query: 8  EFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFS 51
          E+DVIV+GTGL E I++   S +G++VLH+D   YYGG  AS +
Sbjct: 4  EYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASIT 47


>gi|169646441 GDP dissociation inhibitor 2 isoform 2 [Homo sapiens]
          Length = 400

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 63/269 (23%), Positives = 119/269 (44%), Gaps = 29/269 (10%)

Query: 289 MVEKRMLMKFLTFCMEY-EKYPDEYKGYE--EITFYEYLKTQKLTPNLQYIVMHSIAM-- 343
           + EKR   KFL +   + EK P  ++G +  + T  +  K   L  ++     H++A+  
Sbjct: 89  LFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALALYR 148

Query: 344 ----TSETASSTIDGLKATKNFLHCLGRYGNTPFLFPLYGQGELPQCFCRMCAVFGGIYC 399
                 +    TI+ +K    +   L RYG +P+L+PLYG GELPQ F R+ A++GG Y 
Sbjct: 149 TDDYLDQPCYETINRIKL---YSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYM 205

Query: 400 LRHSVQCLVVDKESRKCKAI-IDQFGQRIISEHFLVEDSYFPENMCSRVQYRQISRAVLI 458
           L   ++ ++V    +  K I +   G+    +  + + SY  + +    +  Q+ R + I
Sbjct: 206 LNKPIEEIIV----QNGKVIGVKSEGEIARCKQLICDPSYVKDRV---EKVGQVIRVICI 258

Query: 459 TDRSVLKTDSDQQISILTVPAEEPGTFAVRVIELCSSTMTCMKGTYLVHLTCT------- 511
               +  T+      I+    +      + V  +  +     +G Y+  ++ T       
Sbjct: 259 LSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPE 318

Query: 512 -SSKTAREDLESVVQKLFVPYTEMEIENE 539
              + A E LE + QK FV  +++ +  +
Sbjct: 319 KEIRPALELLEPIEQK-FVSISDLLVPKD 346



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 23/44 (52%), Positives = 32/44 (72%)

Query: 8  EFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFS 51
          E+DVIV+GTGL E I++   S +G++VLH+D   YYGG  AS +
Sbjct: 4  EYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASIT 47


>gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens]
          Length = 610

 Score = 38.1 bits (87), Expect = 0.026
 Identities = 19/54 (35%), Positives = 33/54 (61%)

Query: 2   ADTLPSEFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFSFSGL 55
           A+ +P + DV+VIG+G      AA  +++G+RVL ++  +  GG   +F  +GL
Sbjct: 61  ANQVPEKLDVVVIGSGFGGLAAAAILAKAGKRVLVLEQHTKAGGCCHTFGKNGL 114


>gi|13654239 WW domain containing E3 ubiquitin protein ligase 1
           [Homo sapiens]
          Length = 922

 Score = 33.5 bits (75), Expect = 0.63
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 15/91 (16%)

Query: 129 NSTEAADSAFLPTEDESLSTMSCEMLTEQTPSSDPENALEVNGAEVTGEKE------NHC 182
           ++     S+F PT++ S++          TP    ENAL  N    T E           
Sbjct: 240 DTVNGESSSFAPTDNASVTG---------TPVVSEENALSPNCTSTTVEDPPVQEILTSS 290

Query: 183 DDKTCVPSTSAEDMSENVPIAEDTTEQPKKN 213
           ++  C+PSTSAE  SE   I E  T   + +
Sbjct: 291 ENNECIPSTSAELESEARSILEPDTSNSRSS 321


>gi|163310725 ER degradation enhancer, mannosidase alpha-like 3
           [Homo sapiens]
          Length = 932

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 30/117 (25%), Positives = 55/117 (47%), Gaps = 6/117 (5%)

Query: 55  LLSWLKEYQENSDIVSDSPVWQDQILENEEAIALSRKDKTIQHVEVFCYASQD---LHED 111
           +L  ++EY+E   ++SD    +D  +ENEE  + S  D   Q  E    +SQ+   + ++
Sbjct: 775 ILDAIREYEEVEVLLSDKAKDRDPEMENEEQPS-SENDSQNQSGEQISSSSQEVDLVDQE 833

Query: 112 VEEAGALQKNHALVTSANSTEAADSAFLPTEDESLSTMSCEMLTEQTPSSDPENALE 168
             E  +L  +   ++ A+   AA  +  P+E  S  T + E        +D +N L+
Sbjct: 834 SSEENSLNSHPESLSLADMDNAA--SISPSEQTSNPTENHETTNLNGECTDLDNQLQ 888


>gi|194097489 RAN binding protein 3 isoform RANBP3-b [Homo sapiens]
          Length = 499

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 38/158 (24%), Positives = 65/158 (41%), Gaps = 30/158 (18%)

Query: 84  EAIALSRKDKTIQHVEVFCYASQD----LHEDVEEAGALQKNH----------------- 122
           E  A  +KD   Q   VF    +D    ++E V+EA      H                 
Sbjct: 177 EEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFLQYIS 236

Query: 123 -ALVTSANSTEAADSAFLPTEDESLSTMSCEMLTEQTPSSDPENALEVNGA-----EVTG 176
            +L  S NS +A+ + F+  ++ S   +S   L E +  ++ ENA   +G+     E T 
Sbjct: 237 SSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATP 296

Query: 177 EKENHCDDKTC-VPSTSAEDMSENVPIAEDTTEQPKKN 213
           EKE+  +       +T+ + + E V +   T E+ + N
Sbjct: 297 EKESLAESAAAYTKATARKCLLEKVEVI--TGEEAESN 332


>gi|194097487 RAN binding protein 3 isoform RANBP3-a [Homo sapiens]
          Length = 562

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 38/158 (24%), Positives = 65/158 (41%), Gaps = 30/158 (18%)

Query: 84  EAIALSRKDKTIQHVEVFCYASQD----LHEDVEEAGALQKNH----------------- 122
           E  A  +KD   Q   VF    +D    ++E V+EA      H                 
Sbjct: 240 EEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFLQYIS 299

Query: 123 -ALVTSANSTEAADSAFLPTEDESLSTMSCEMLTEQTPSSDPENALEVNGA-----EVTG 176
            +L  S NS +A+ + F+  ++ S   +S   L E +  ++ ENA   +G+     E T 
Sbjct: 300 SSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATP 359

Query: 177 EKENHCDDKTC-VPSTSAEDMSENVPIAEDTTEQPKKN 213
           EKE+  +       +T+ + + E V +   T E+ + N
Sbjct: 360 EKESLAESAAAYTKATARKCLLEKVEVI--TGEEAESN 395


>gi|6466466 RAN binding protein 3 isoform RANBP3-d [Homo sapiens]
          Length = 567

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 38/158 (24%), Positives = 65/158 (41%), Gaps = 30/158 (18%)

Query: 84  EAIALSRKDKTIQHVEVFCYASQD----LHEDVEEAGALQKNH----------------- 122
           E  A  +KD   Q   VF    +D    ++E V+EA      H                 
Sbjct: 245 EEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFLQYIS 304

Query: 123 -ALVTSANSTEAADSAFLPTEDESLSTMSCEMLTEQTPSSDPENALEVNGA-----EVTG 176
            +L  S NS +A+ + F+  ++ S   +S   L E +  ++ ENA   +G+     E T 
Sbjct: 305 SSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATP 364

Query: 177 EKENHCDDKTC-VPSTSAEDMSENVPIAEDTTEQPKKN 213
           EKE+  +       +T+ + + E V +   T E+ + N
Sbjct: 365 EKESLAESAAAYTKATARKCLLEKVEVI--TGEEAESN 400


>gi|238550202 tubby like protein 3 isoform 2 [Homo sapiens]
          Length = 501

 Score = 31.2 bits (69), Expect = 3.1
 Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 7/104 (6%)

Query: 506 VHLTCTSSKTAREDLESVVQKLFVPYTEMEIENEQVEKPRILWALYFNMRDSSDISRSCY 565
           VH    SS    ED E+ V     P  +     E+++K  I  ++ F+  ++  IS+S  
Sbjct: 98  VHAPSVSSSVVEEDAENTVDTASKPGLQ-----ERLQKHDISESVNFD-EETDGISQSAC 151

Query: 566 NDLPSNVYVCSGPDCGL-GNDNAVKQAETLFQEICPNEDFCPPP 608
            + P++    +  D G  G+  A + A+ L  +I   EDF   P
Sbjct: 152 LERPNSASSQNSTDTGTSGSATAAQPADNLLGDIDDLEDFVYSP 195


>gi|21536436 tubby like protein 3 isoform 1 [Homo sapiens]
          Length = 442

 Score = 31.2 bits (69), Expect = 3.1
 Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 7/104 (6%)

Query: 506 VHLTCTSSKTAREDLESVVQKLFVPYTEMEIENEQVEKPRILWALYFNMRDSSDISRSCY 565
           VH    SS    ED E+ V     P  +     E+++K  I  ++ F+  ++  IS+S  
Sbjct: 98  VHAPSVSSSVVEEDAENTVDTASKPGLQ-----ERLQKHDISESVNFD-EETDGISQSAC 151

Query: 566 NDLPSNVYVCSGPDCGL-GNDNAVKQAETLFQEICPNEDFCPPP 608
            + P++    +  D G  G+  A + A+ L  +I   EDF   P
Sbjct: 152 LERPNSASSQNSTDTGTSGSATAAQPADNLLGDIDDLEDFVYSP 195


>gi|52630429 nuclear factor, interleukin 3 regulated [Homo sapiens]
          Length = 462

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 33/149 (22%), Positives = 65/149 (43%), Gaps = 7/149 (4%)

Query: 77  DQILENEEAIALSRKDKTIQHVEVFCYASQDLHEDVEEAGALQK--NHALV--TSANSTE 132
           D +LEN+  IAL  ++ T++   +       L      A  +QK  N   V      +++
Sbjct: 98  DLVLENK-LIALGEENATLKAELLSLKLKFGLISSTAYAQEIQKLSNSTAVYFQDYQTSK 156

Query: 133 AADSAFLPTEDESLSTMSCEMLTEQTPSSDPENALEVNGAEVTGEKENHCDDKTCVPSTS 192
           +  S+F+   + S+ + SC  + + +P S   +  EV+  E T  +E+        P   
Sbjct: 157 SNVSSFVDEHEPSMVSSSCISVIKHSPQSSLSDVSEVSSVEHT--QESSVQGSCRSPENK 214

Query: 193 AEDMSENVPIAEDTTEQPKKNRITYSQII 221
            + + +     E  T +P+ +R +Y+  I
Sbjct: 215 FQIIKQEPMELESYTREPRDDRGSYTASI 243


>gi|7662088 Rho guanine nucleotide exchange factor (GEF) 12 [Homo
            sapiens]
          Length = 1544

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 5/98 (5%)

Query: 92   DKTIQHVE-VFCYASQDLHEDVEEA-GALQKNHALVTSANSTEAADSAFLPTEDESLST- 148
            D  IQ+ E +  Y S + H       G +   ++  TS  S    DS  L  +D   S  
Sbjct: 1294 DSVIQNSENIKAYHSGEGHMPFRTGTGDIATCYSPRTSTESFAPRDSVGLAPQDSQASNI 1353

Query: 149  --MSCEMLTEQTPSSDPENALEVNGAEVTGEKENHCDD 184
              M   ++T + P+ +PE  L+ +G      +E H D+
Sbjct: 1354 LVMDHMIMTPEMPTMEPEGGLDDSGEHFFDAREAHSDE 1391


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 30.4 bits (67), Expect = 5.4
 Identities = 15/87 (17%), Positives = 42/87 (48%)

Query: 127  SANSTEAADSAFLPTEDESLSTMSCEMLTEQTPSSDPENALEVNGAEVTGEKENHCDDKT 186
            S++S++++DS+      +S  +      ++ + SSD  ++ + N +  + +  +  D   
Sbjct: 1189 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSN 1248

Query: 187  CVPSTSAEDMSENVPIAEDTTEQPKKN 213
               S+ + D S++   + D ++   K+
Sbjct: 1249 SSDSSDSSDSSDSTSDSNDESDSQSKS 1275


>gi|160420295 hypothetical protein LOC85459 [Homo sapiens]
          Length = 2601

 Score = 30.4 bits (67), Expect = 5.4
 Identities = 28/115 (24%), Positives = 50/115 (43%), Gaps = 6/115 (5%)

Query: 107  DLHEDVEEAGALQKNHALVTSANSTEAADSAFLPTEDESLSTMSCEMLTEQTPSSDPENA 166
            D  E V+   ++ +NHA+++ A   E A        D+   T+S E L+  T S+    +
Sbjct: 1912 DYDEAVKLKESVVENHAVLSYAVEEEHAYLGPTVKPDDKAKTLSYEPLSSATVSTGSLLS 1971

Query: 167  LEVNGAEVTGEK--ENHCDDKTCVPSTSAED----MSENVPIAEDTTEQPKKNRI 215
             E     +T  +    H DD     +TS E+    +S  VP  +D  ++   + +
Sbjct: 1972 YENTDLSLTDPESFSEHMDDSKQESTTSKEEETNIISSIVPSTQDIYQRQNSSDV 2026


>gi|41393608 reticulon 3 isoform b [Homo sapiens]
          Length = 1013

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 38/160 (23%), Positives = 59/160 (36%), Gaps = 22/160 (13%)

Query: 140 PTEDESLSTMSCEMLTEQTPSSDPENALEVNGAEVTGEKENHCD-----------DKTC- 187
           P    S    + E   ++ PS + E     N  E+  + E H D           +  C 
Sbjct: 505 PVSIPSAVVKTGEREIKEIPSCEREEKTSKNFEELVSDSELHQDQPDILGRSPASEAACS 564

Query: 188 -VPST--SAEDMSENVPIAEDTTEQPKKNRITYSQIIKEGRRFNIDLVSKLLYSRGLLID 244
            VP T  S ED+SE  P    TTE PK        +  E   F++++ +         ++
Sbjct: 565 KVPDTNVSLEDVSEVAPEKPITTENPKLPSTVSPNVFNE-TEFSLNVTT------SAYLE 617

Query: 245 LLIKSNVSRYAEFKNITRILAFREGRVEQVPCSRADVFNS 284
            L   NV    +      I AF E R + +  S  + F +
Sbjct: 618 SLHGKNVKHIDDSSPEDLIAAFTETRDKGIVDSERNAFKA 657


>gi|239757925 PREDICTED: similar to melanoma antigen family C, 2
           [Homo sapiens]
          Length = 347

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 1/68 (1%)

Query: 98  VEVFCYASQDLHEDVEEAGALQKNHALVTSANSTEAADSAFLP-TEDESLSTMSCEMLTE 156
           +E +  A     E+ EEA        LV S++S+ ++ S  L   E+E + +     L +
Sbjct: 22  IEDWIDAQDPTDEEEEEASISSSTFYLVFSSSSSSSSSSLILGGPEEEEVHSAGMSSLLQ 81

Query: 157 QTPSSDPE 164
            TP S P+
Sbjct: 82  STPKSPPQ 89


>gi|239754799 PREDICTED: similar to hCG1797215 [Homo sapiens]
          Length = 93

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 4/39 (10%)

Query: 45 GNWASFSFSGLLSWLKEYQENSDIVSD----SPVWQDQI 79
          G+W    F G  + L   QE  DI+SD     P+W+++I
Sbjct: 53 GSWGKGLFDGQQNELLRKQEREDIISDLRQRRPIWKEEI 91


>gi|239752435 PREDICTED: similar to melanoma antigen family C, 2
           [Homo sapiens]
          Length = 424

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 1/68 (1%)

Query: 98  VEVFCYASQDLHEDVEEAGALQKNHALVTSANSTEAADSAFLP-TEDESLSTMSCEMLTE 156
           +E +  A     E+ EEA        LV S++S+ ++ S  L   E+E + +     L +
Sbjct: 99  IEDWIDAQDPTDEEEEEASISSSTFYLVFSSSSSSSSSSLILGGPEEEEVHSAGMSSLLQ 158

Query: 157 QTPSSDPE 164
            TP S P+
Sbjct: 159 STPKSPPQ 166


>gi|239749323 PREDICTED: similar to hCG1797215 [Homo sapiens]
          Length = 93

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 4/39 (10%)

Query: 45 GNWASFSFSGLLSWLKEYQENSDIVSD----SPVWQDQI 79
          G+W    F G  + L   QE  DI+SD     P+W+++I
Sbjct: 53 GSWGKGLFDGQQNELLRKQEREDIISDLRQRRPIWKEEI 91


>gi|239746952 PREDICTED: similar to melanoma antigen family C, 2
           [Homo sapiens]
          Length = 424

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 1/68 (1%)

Query: 98  VEVFCYASQDLHEDVEEAGALQKNHALVTSANSTEAADSAFLP-TEDESLSTMSCEMLTE 156
           +E +  A     E+ EEA        LV S++S+ ++ S  L   E+E + +     L +
Sbjct: 99  IEDWIDAQDPTDEEEEEASISSSTFYLVFSSSSSSSSSSLILGGPEEEEVHSAGMSSLLQ 158

Query: 157 QTPSSDPE 164
            TP S P+
Sbjct: 159 STPKSPPQ 166


>gi|239743413 PREDICTED: hypothetical protein XP_002342849 [Homo
          sapiens]
          Length = 93

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 4/39 (10%)

Query: 45 GNWASFSFSGLLSWLKEYQENSDIVSD----SPVWQDQI 79
          G+W    F G  + L   QE  DI+SD     P+W+++I
Sbjct: 53 GSWGKGLFDGQQNELLRKQEREDIISDLRQRRPIWKEEI 91


>gi|239509120 PREDICTED: similar to hCG1797215 [Homo sapiens]
          Length = 93

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 4/39 (10%)

Query: 45 GNWASFSFSGLLSWLKEYQENSDIVSD----SPVWQDQI 79
          G+W    F G  + L   QE  DI+SD     P+W+++I
Sbjct: 53 GSWGKGLFDGQQNELLRKQEREDIISDLRQRRPIWKEEI 91


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 32/142 (22%), Positives = 60/142 (42%), Gaps = 28/142 (19%)

Query: 81  ENEEAIALSRKDKTIQHVEVFCYASQDLHEDVEEAGALQKNHALVTSANSTEAADSAFLP 140
           EN+E + L+  D            S++LH   +            + + S E A+     
Sbjct: 70  ENDEPLNLNASDSE----------SEELHRQKD------------SDSESEERAEPPASD 107

Query: 141 TEDESLSTMSCEMLTEQT---PSSDPENALEVNGAEVTGEKENHCDDKTCVPSTSAEDMS 197
           +E+E ++    +  +E+T   P SD EN   +NG     + EN    K     +  E++ 
Sbjct: 108 SENEDVNQHGSDSESEETRKLPGSDSENEELLNGH--ASDSENEDVGKHPASDSEIEELQ 165

Query: 198 ENVPIAEDTTEQPKKNRITYSQ 219
           ++ P ++  TE   K +I+ S+
Sbjct: 166 KS-PASDSETEDALKPQISDSE 186


>gi|11545835 TSPY-like 2 [Homo sapiens]
          Length = 693

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 26/126 (20%), Positives = 50/126 (39%), Gaps = 14/126 (11%)

Query: 103 YASQDLHEDVEEAGALQKNHALVTSANSTEAADSAFLPTEDESLSTMSCEMLTEQTPSSD 162
           YA +D+  ++ +      +  +     +T+     +  T D  ++ ++  +   + P  +
Sbjct: 431 YAVEDIFSEISDIDETIHDIKISDFMETTD-----YFETTDNEITDINENICDSENPDHN 485

Query: 163 PENALEVNGAEVTGEKENHCDDKTCVPSTSAEDMSENV----PIAEDTTEQPKKNRITYS 218
                EV   E T   E+  D +T   + SA+D +EN        +D  E P  N  TY 
Sbjct: 486 -----EVPNNETTDNNESADDHETTDNNESADDNNENPEDNNKNTDDNEENPNNNENTYG 540

Query: 219 QIIKEG 224
               +G
Sbjct: 541 NNFFKG 546


>gi|4758274 erythrocyte membrane protein band 4.1 (elliptocytosis 1,
           RH-linked) isoform 3 [Homo sapiens]
          Length = 588

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 34/149 (22%), Positives = 60/149 (40%), Gaps = 17/149 (11%)

Query: 81  ENEEAIALSRKDKTIQHVEVFCYASQDLHEDVEEAGA-LQKNHALVTSA--NSTEAADSA 137
           E E   A  +K + +    ++   S  + ED++++   ++K+HA ++    N  E+    
Sbjct: 398 EPEPTEAWKKKRERLDGENIYIRHSNLMLEDLDKSQEEIKKHHASISELKKNFMESVPEP 457

Query: 138 FLPTEDESLSTMSCEMLTEQTPSSDPENALEVNGAEVTGEKENHCDDKTCVPSTSAEDMS 197
                D+ LST S            P   L +NG   TGE       +T   S +A  + 
Sbjct: 458 RPSEWDKRLSTHS------------PFRTLNINGQIPTGEGPPLVKTQTVTISDNANAVK 505

Query: 198 ENVPIAEDTTEQPKKNRITY--SQIIKEG 224
             +P  +      +   ITY  +Q +K G
Sbjct: 506 SEIPTKDVPIVHTETKTITYEAAQTVKGG 534


>gi|187936949 solute carrier family 39 (zinc transporter), member 10
           [Homo sapiens]
          Length = 831

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 13/101 (12%)

Query: 416 CKAIIDQFGQRIISEHF---LVED-----SYFPENMCSRVQYRQISRAVLITDRSVLKTD 467
           C A++ Q   R+  EHF   LVED     +  PE+  +      I   + IT  S+L   
Sbjct: 364 CPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLLSL- 422

Query: 468 SDQQISILTVPAEEPGTFAVRVIELCSSTMTCMKGTYLVHL 508
               + ++ VP    G F   +  L +  +  M G  L+HL
Sbjct: 423 ----LGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHL 459


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,830,678
Number of Sequences: 37866
Number of extensions: 1143183
Number of successful extensions: 3673
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 3557
Number of HSP's gapped (non-prelim): 128
length of query: 653
length of database: 18,247,518
effective HSP length: 109
effective length of query: 544
effective length of database: 14,120,124
effective search space: 7681347456
effective search space used: 7681347456
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.