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Search of human proteins with 95113651
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|95113651 glutaredoxin 3 [Homo sapiens]
(335 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|95113651 glutaredoxin 3 [Homo sapiens] 667 0.0
gi|42516576 glutaredoxin 5 [Homo sapiens] 100 1e-21
gi|4759274 thioredoxin-like 1 [Homo sapiens] 59 6e-09
gi|50592994 thioredoxin [Homo sapiens] 59 8e-09
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap... 52 7e-07
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap... 52 7e-07
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi... 52 7e-07
gi|51510891 thioredoxin domain containing 8 [Homo sapiens] 46 4e-05
gi|94966757 protein disulfide isomerase A2 [Homo sapiens] 44 2e-04
gi|4758304 protein disulfide isomerase A4 [Homo sapiens] 44 2e-04
gi|148839372 thioredoxin domain containing 3 [Homo sapiens] 44 2e-04
gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens] 42 6e-04
gi|42794771 thioredoxin domain containing 5 isoform 1 precursor ... 42 8e-04
gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo sap... 42 8e-04
gi|21361403 thioredoxin 2 precursor [Homo sapiens] 41 0.002
gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s... 40 0.002
gi|40254947 thioredoxin-related transmembrane protein 4 [Homo sa... 40 0.003
gi|5803121 protein disulfide isomerase A5 [Homo sapiens] 39 0.005
gi|32967591 phosducin isoform a [Homo sapiens] 39 0.005
gi|12408668 phosducin isoform b [Homo sapiens] 39 0.005
gi|5729802 thioredoxin-like 4A [Homo sapiens] 39 0.005
gi|215272376 thioredoxin-like 4B [Homo sapiens] 39 0.007
gi|214832254 thioredoxin-like 4B [Homo sapiens] 39 0.007
gi|8923475 thioredoxin-like 4B [Homo sapiens] 39 0.007
gi|88758594 phosducin-like [Homo sapiens] 38 0.011
gi|54633317 thioredoxin domain containing 11 [Homo sapiens] 38 0.015
gi|18104959 thioredoxin domain containing 9 [Homo sapiens] 37 0.019
gi|151101292 thioredoxin domain containing 1 [Homo sapiens] 37 0.025
gi|51944950 phosducin-like 2 [Homo sapiens] 37 0.025
gi|52487191 thioredoxin domain containing 4 (endoplasmic reticul... 36 0.042
>gi|95113651 glutaredoxin 3 [Homo sapiens]
Length = 335
Score = 667 bits (1720), Expect = 0.0
Identities = 335/335 (100%), Positives = 335/335 (100%)
Query: 1 MAAGAAEAAVAAVEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKEL 60
MAAGAAEAAVAAVEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKEL
Sbjct: 1 MAAGAAEAAVAAVEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKEL 60
Query: 61 PQVSFVKLEAEGVPEVSEKYEISSVPTFLFFKNSQKIDRLDGAHAPELTKKVQRHASSGS 120
PQVSFVKLEAEGVPEVSEKYEISSVPTFLFFKNSQKIDRLDGAHAPELTKKVQRHASSGS
Sbjct: 61 PQVSFVKLEAEGVPEVSEKYEISSVPTFLFFKNSQKIDRLDGAHAPELTKKVQRHASSGS 120
Query: 121 FLPSANEHLKEDLNLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFD 180
FLPSANEHLKEDLNLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFD
Sbjct: 121 FLPSANEHLKEDLNLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFD 180
Query: 181 IFSDEEVRQGLKAYSSWPTYPQLYVSGELIGGLDIIKELEASEELDTICPKAPKLEERLK 240
IFSDEEVRQGLKAYSSWPTYPQLYVSGELIGGLDIIKELEASEELDTICPKAPKLEERLK
Sbjct: 181 IFSDEEVRQGLKAYSSWPTYPQLYVSGELIGGLDIIKELEASEELDTICPKAPKLEERLK 240
Query: 241 VLTNKASVMLFMKGNKQEAKCGFSKQILEILNSTGVEYETFDILEDEEVRQGLKAYSNWP 300
VLTNKASVMLFMKGNKQEAKCGFSKQILEILNSTGVEYETFDILEDEEVRQGLKAYSNWP
Sbjct: 241 VLTNKASVMLFMKGNKQEAKCGFSKQILEILNSTGVEYETFDILEDEEVRQGLKAYSNWP 300
Query: 301 TYPQLYVKGELVGGLDIVKELKENGELLPILRGEN 335
TYPQLYVKGELVGGLDIVKELKENGELLPILRGEN
Sbjct: 301 TYPQLYVKGELVGGLDIVKELKENGELLPILRGEN 335
>gi|42516576 glutaredoxin 5 [Homo sapiens]
Length = 157
Score = 100 bits (250), Expect = 1e-21
Identities = 44/97 (45%), Positives = 70/97 (72%), Gaps = 1/97 (1%)
Query: 237 ERLKVLTNKASVMLFMKGNKQEAKCGFSKQILEILNSTGV-EYETFDILEDEEVRQGLKA 295
E+L L K V++F+KG ++ +CGFS +++IL GV +Y +++L+D E+RQG+K
Sbjct: 43 EQLDALVKKDKVVVFLKGTPEQPQCGFSNAVVQILRLHGVRDYAAYNVLDDPELRQGIKD 102
Query: 296 YSNWPTYPQLYVKGELVGGLDIVKELKENGELLPILR 332
YSNWPT PQ+Y+ GE VGG DI+ ++ +NG+L+ L+
Sbjct: 103 YSNWPTIPQVYLNGEFVGGCDILLQMHQNGDLVEELK 139
Score = 91.7 bits (226), Expect = 8e-19
Identities = 37/91 (40%), Positives = 66/91 (72%), Gaps = 1/91 (1%)
Query: 136 RLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQ-FSSFDIFSDEEVRQGLKAY 194
+L L ++F+KGTP++P+CGFS +V+IL H ++ ++++++ D E+RQG+K Y
Sbjct: 44 QLDALVKKDKVVVFLKGTPEQPQCGFSNAVVQILRLHGVRDYAAYNVLDDPELRQGIKDY 103
Query: 195 SSWPTYPQLYVSGELIGGLDIIKELEASEEL 225
S+WPT PQ+Y++GE +GG DI+ ++ + +L
Sbjct: 104 SNWPTIPQVYLNGEFVGGCDILLQMHQNGDL 134
>gi|4759274 thioredoxin-like 1 [Homo sapiens]
Length = 289
Score = 58.9 bits (141), Expect = 6e-09
Identities = 34/118 (28%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
Query: 10 VAAVEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLE 69
+ V+ VGS F+ L L VV F C ++ + ++ + PQ F++++
Sbjct: 1 MVGVKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVD 60
Query: 70 AEGVPEVSEKYEISSVPTFLFFKNSQKIDRLDGAHAPELTKKVQRHASSGSFLPSANE 127
+ IS+ PTFLFF+N +ID+ GA A L +K+++H + P +NE
Sbjct: 61 VHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLEND---PGSNE 115
>gi|50592994 thioredoxin [Homo sapiens]
Length = 105
Score = 58.5 bits (140), Expect = 8e-09
Identities = 28/96 (29%), Positives = 50/96 (52%)
Query: 13 VEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAEG 72
V+++ S F+E L L+VV F A W C + L+++ V F++++ +
Sbjct: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
Query: 73 VPEVSEKYEISSVPTFLFFKNSQKIDRLDGAHAPEL 108
+V+ + E+ +PTF FFK QK+ GA+ +L
Sbjct: 62 CQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKL 97
>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 52.0 bits (123), Expect = 7e-07
Identities = 29/91 (31%), Positives = 46/91 (50%)
Query: 13 VEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAEG 72
V+ + S FE L+ + L+ V F A W C + L+ + V F++++A+
Sbjct: 383 VKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADN 442
Query: 73 VPEVSEKYEISSVPTFLFFKNSQKIDRLDGA 103
EV + I VPTF F+K +K+D L GA
Sbjct: 443 CEEVVRECAIMCVPTFQFYKKEEKVDELCGA 473
>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
sapiens]
Length = 553
Score = 52.0 bits (123), Expect = 7e-07
Identities = 29/91 (31%), Positives = 46/91 (50%)
Query: 13 VEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAEG 72
V+ + S FE L+ + L+ V F A W C + L+ + V F++++A+
Sbjct: 450 VKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADN 509
Query: 73 VPEVSEKYEISSVPTFLFFKNSQKIDRLDGA 103
EV + I VPTF F+K +K+D L GA
Sbjct: 510 CEEVVRECAIMCVPTFQFYKKEEKVDELCGA 540
>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 52.0 bits (123), Expect = 7e-07
Identities = 29/91 (31%), Positives = 46/91 (50%)
Query: 13 VEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAEG 72
V+ + S FE L+ + L+ V F A W C + L+ + V F++++A+
Sbjct: 383 VKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADN 442
Query: 73 VPEVSEKYEISSVPTFLFFKNSQKIDRLDGA 103
EV + I VPTF F+K +K+D L GA
Sbjct: 443 CEEVVRECAIMCVPTFQFYKKEEKVDELCGA 473
>gi|51510891 thioredoxin domain containing 8 [Homo sapiens]
Length = 115
Score = 46.2 bits (108), Expect = 4e-05
Identities = 24/85 (28%), Positives = 40/85 (47%)
Query: 13 VEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAEG 72
V+ + +F+ L L VV F + C +M V ++ + V F ++
Sbjct: 2 VQIIKDTNEFKTFLTAAGHKLAVVQFSSKRCGPCKRMFPVFHAMSVKYQNVFFANVDVNN 61
Query: 73 VPEVSEKYEISSVPTFLFFKNSQKI 97
PE++E I ++PTF FK SQK+
Sbjct: 62 SPELAETCHIKTIPTFQMFKKSQKV 86
>gi|94966757 protein disulfide isomerase A2 [Homo sapiens]
Length = 525
Score = 43.9 bits (102), Expect = 2e-04
Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 4/75 (5%)
Query: 26 LRLKAKSLLVVHFWAPWAPQCAQM----NEVMAELAKELPQVSFVKLEAEGVPEVSEKYE 81
L L+ L+V F+APW C + ++ A LA E V+ K++ E++E++
Sbjct: 54 LALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFG 113
Query: 82 ISSVPTFLFFKNSQK 96
++ PT FF+N +
Sbjct: 114 VTEYPTLKFFRNGNR 128
>gi|4758304 protein disulfide isomerase A4 [Homo sapiens]
Length = 645
Score = 43.9 bits (102), Expect = 2e-04
Identities = 17/70 (24%), Positives = 38/70 (54%), Gaps = 4/70 (5%)
Query: 33 LLVVHFWAPWAPQCAQM----NEVMAELAKELPQVSFVKLEAEGVPEVSEKYEISSVPTF 88
+++V F+APW C ++ + EL+K P + K++A ++++++++S PT
Sbjct: 196 IILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTL 255
Query: 89 LFFKNSQKID 98
F+ + D
Sbjct: 256 KIFRKGRPYD 265
Score = 42.7 bits (99), Expect = 5e-04
Identities = 24/97 (24%), Positives = 42/97 (43%), Gaps = 5/97 (5%)
Query: 31 KSLLVVHFWAPWAPQCAQMNEVMAELAKEL----PQVSFVKLEAEGVPEVSEKYEISSVP 86
K +++ F+APW C Q ++A L P + K++A ++ ++++S P
Sbjct: 79 KDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYP 138
Query: 87 TFLFFKNSQKIDRLDGAHAPELTKKVQRHASSGSFLP 123
T K Q +D E+ KV R S + P
Sbjct: 139 TIKILKKGQAVDYEGSRTQEEIVAKV-REVSQPDWTP 174
Score = 39.7 bits (91), Expect = 0.004
Identities = 25/105 (23%), Positives = 50/105 (47%), Gaps = 7/105 (6%)
Query: 20 GQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKEL---PQVSFVKLEAEGVPEV 76
G+ + + + K +++ F+APW C Q+ V LAK+ + K++A
Sbjct: 532 GKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVP 591
Query: 77 SEKYEISSVPTFLFFKNSQKID--RLDGA--HAPELTKKVQRHAS 117
S++Y++ PT F + K + + +G L+K ++ HA+
Sbjct: 592 SDRYKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHAT 636
>gi|148839372 thioredoxin domain containing 3 [Homo sapiens]
Length = 588
Score = 43.9 bits (102), Expect = 2e-04
Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 4/88 (4%)
Query: 28 LKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQ---VSFVKLEAEGVPEVSEKYEISS 84
L+ K L V+ + W C M + +L EL + + F EA+ + + + +
Sbjct: 24 LQNKGLTVIDVYQAWCGPCRAMQPLFRKLKNELNEDEILHFAVAEADNIVTL-QPFRDKC 82
Query: 85 VPTFLFFKNSQKIDRLDGAHAPELTKKV 112
P FLF N + I+++ GA+AP + KKV
Sbjct: 83 EPVFLFSVNGKIIEKIQGANAPLVNKKV 110
>gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]
Length = 505
Score = 42.4 bits (98), Expect = 6e-04
Identities = 31/125 (24%), Positives = 57/125 (45%), Gaps = 12/125 (9%)
Query: 19 AGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKEL---PQVSFVKLEAEGVPE 75
A F+E++ + K +L+ F+APW C + EL ++L P + K++A +
Sbjct: 383 AENFDEIVNNENKDVLI-EFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDAT-AND 440
Query: 76 VSEKYEISSVPTFLFFKNSQKIDRL---DGAHAPELTKKVQRHASSGSFL----PSANEH 128
V YE+ PT F ++K++ G + +QR A++ + P +
Sbjct: 441 VPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKK 500
Query: 129 LKEDL 133
+EDL
Sbjct: 501 AQEDL 505
Score = 39.3 bits (90), Expect = 0.005
Identities = 30/133 (22%), Positives = 52/133 (39%), Gaps = 2/133 (1%)
Query: 1 MAAGAAEAAVAAVEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKEL 60
+ A A AA + V E+ + + L++V F+APW C ++ A L
Sbjct: 15 LLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL 74
Query: 61 PQ-VSFVKLEAEGVPEVSEKYEISSVPTFLFFKNSQKIDRLDGAH-APELTKKVQRHASS 118
V K++ KY +S PT F++ ++ DG A + +++ A
Sbjct: 75 KGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGP 134
Query: 119 GSFLPSANEHLKE 131
S E K+
Sbjct: 135 ASVPLRTEEEFKK 147
>gi|42794771 thioredoxin domain containing 5 isoform 1 precursor
[Homo sapiens]
Length = 432
Score = 42.0 bits (97), Expect = 8e-04
Identities = 28/106 (26%), Positives = 44/106 (41%), Gaps = 9/106 (8%)
Query: 6 AEAAVAAVEEVGSAGQFEELLRLK-----AKSLLVVHFWAPWAPQCAQMNEVMAELA-KE 59
+EA V A E G L A+ + + F+APW C + EL+ KE
Sbjct: 308 SEAPVLAAEPEADKGTVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKE 367
Query: 60 LPQVSFVKL---EAEGVPEVSEKYEISSVPTFLFFKNSQKIDRLDG 102
P ++ VK+ + + KY + PT L F+ +K+ G
Sbjct: 368 FPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSG 413
Score = 37.4 bits (85), Expect = 0.019
Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 9/73 (12%)
Query: 36 VHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAEGVPEVSEKYEISS------VPTFL 89
+ F+APW C + +LA L VK+ G + ++ YE+ S PT L
Sbjct: 210 IKFFAPWCGHCKALAPTWEQLALGLEHSETVKI---GKVDCTQHYELCSGNQVRGYPTLL 266
Query: 90 FFKNSQKIDRLDG 102
+F++ +K+D+ G
Sbjct: 267 WFRDGKKVDQYKG 279
>gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo
sapiens]
Length = 324
Score = 42.0 bits (97), Expect = 8e-04
Identities = 28/106 (26%), Positives = 44/106 (41%), Gaps = 9/106 (8%)
Query: 6 AEAAVAAVEEVGSAGQFEELLRLK-----AKSLLVVHFWAPWAPQCAQMNEVMAELA-KE 59
+EA V A E G L A+ + + F+APW C + EL+ KE
Sbjct: 200 SEAPVLAAEPEADKGTVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKE 259
Query: 60 LPQVSFVKL---EAEGVPEVSEKYEISSVPTFLFFKNSQKIDRLDG 102
P ++ VK+ + + KY + PT L F+ +K+ G
Sbjct: 260 FPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSG 305
Score = 37.4 bits (85), Expect = 0.019
Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 9/73 (12%)
Query: 36 VHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAEGVPEVSEKYEISS------VPTFL 89
+ F+APW C + +LA L VK+ G + ++ YE+ S PT L
Sbjct: 102 IKFFAPWCGHCKALAPTWEQLALGLEHSETVKI---GKVDCTQHYELCSGNQVRGYPTLL 158
Query: 90 FFKNSQKIDRLDG 102
+F++ +K+D+ G
Sbjct: 159 WFRDGKKVDQYKG 171
>gi|21361403 thioredoxin 2 precursor [Homo sapiens]
Length = 166
Score = 40.8 bits (94), Expect = 0.002
Identities = 21/76 (27%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Query: 28 LKAKSLLVVHFWAPWAPQCAQMNEVMAEL-AKELPQVSFVKLEAEGVPEVSEKYEISSVP 86
+ +++ +VV F A W C + + ++ AK+ +V K++ + +++ +YE+S+VP
Sbjct: 75 VNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVP 134
Query: 87 TFLFFKNSQKIDRLDG 102
T L KN +D+ G
Sbjct: 135 TVLAMKNGDVVDKFVG 150
>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
sapiens]
Length = 508
Score = 40.4 bits (93), Expect = 0.002
Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 4/70 (5%)
Query: 28 LKAKSLLVVHFWAPWAPQCAQMNEVMAELAKEL----PQVSFVKLEAEGVPEVSEKYEIS 83
L A L+V F+APW C + A+ A +L ++ K++A +++++Y +
Sbjct: 38 LAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVR 97
Query: 84 SVPTFLFFKN 93
PT FF+N
Sbjct: 98 GYPTIKFFRN 107
Score = 30.4 bits (67), Expect = 2.3
Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Query: 31 KSLLVVHFWAPWAPQCAQMNEV---MAELAKELPQVSFVKLEAEGVPEVSEKYEISSVPT 87
K + V F+APW C Q+ + + E K+ + K+++ E ++ S PT
Sbjct: 385 KKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDS--TANEVEAVKVHSFPT 442
Query: 88 FLFFKNS 94
FF S
Sbjct: 443 LKFFPAS 449
>gi|40254947 thioredoxin-related transmembrane protein 4 [Homo
sapiens]
Length = 349
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 9/98 (9%)
Query: 5 AAEAAVAAVEEVGSAGQFEELLRLKAKSLLVV-------HFWAPWAPQCAQMNEVMAELA 57
AA AA A EE + + + A + +V F+APW P C Q + A
Sbjct: 19 AAVAATAGPEEAALPPEQSRVQPMTASNWTLVMEGEWMLKFYAPWCPSCQQTDSEWEAFA 78
Query: 58 K--ELPQVSFVKLEAEGVPEVSEKYEISSVPTFLFFKN 93
K E+ Q+S K++ P +S ++ ++++P F K+
Sbjct: 79 KNGEILQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKD 116
>gi|5803121 protein disulfide isomerase A5 [Homo sapiens]
Length = 519
Score = 39.3 bits (90), Expect = 0.005
Identities = 41/167 (24%), Positives = 75/167 (44%), Gaps = 22/167 (13%)
Query: 13 VEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKEL---PQVSFVKLE 69
V + S F LL+ + K LL++ F+APW C +M + A +L ++ + +
Sbjct: 153 VVHLDSEKDFRRLLKKEEKPLLIM-FYAPWCSMCKRMMPHFQKAATQLRGHAVLAGMNVY 211
Query: 70 AEGVPEVSEKYEISSVPTFLFFKNSQKIDRLD--GAHAPELT---KKVQRHASSGSFLPS 124
+ + E+Y + PT +F+ + + + D G+ A ++ K Q P
Sbjct: 212 SSEFENIKEEYSVRGFPTICYFEKGRFLFQYDNYGSTAEDIVEWLKNPQPPQPQVPETPW 271
Query: 125 ANE-----HL-KEDLNLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQM 165
A+E HL ED + +K+ H++ ++F P CG K+M
Sbjct: 272 ADEGGSVYHLTDEDFDQFVKE--HSSVLVMF-----HAPWCGHCKKM 311
Score = 37.0 bits (84), Expect = 0.025
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
Query: 28 LKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVS-----FVKLEAEGVPEVSEKYEI 82
+K S ++V F APW C +M + A+ L + ++A ++E++ I
Sbjct: 290 VKEHSSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSGVLAAVDATVNKALAERFHI 349
Query: 83 SSVPTFLFFKNSQK 96
S PT +FKN +K
Sbjct: 350 SEFPTLKYFKNGEK 363
>gi|32967591 phosducin isoform a [Homo sapiens]
Length = 246
Score = 39.3 bits (90), Expect = 0.005
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Query: 13 VEEVGSAGQFEELLRLKAK-SLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAE 71
V E+ + QF E + + K + +VVH + C +N + LA E P V F K++A
Sbjct: 114 VYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKAS 173
Query: 72 GVPEVSEKYEISSVPTFLFFKNSQKI 97
+++ + +PT L +K + I
Sbjct: 174 NT-GAGDRFSLDVLPTLLIYKGGELI 198
>gi|12408668 phosducin isoform b [Homo sapiens]
Length = 194
Score = 39.3 bits (90), Expect = 0.005
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Query: 13 VEEVGSAGQFEELLRLKAK-SLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAE 71
V E+ + QF E + + K + +VVH + C +N + LA E P V F K++A
Sbjct: 62 VYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKAS 121
Query: 72 GVPEVSEKYEISSVPTFLFFKNSQKI 97
+++ + +PT L +K + I
Sbjct: 122 NT-GAGDRFSLDVLPTLLIYKGGELI 146
>gi|5729802 thioredoxin-like 4A [Homo sapiens]
Length = 142
Score = 39.3 bits (90), Expect = 0.005
Identities = 19/78 (24%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
Query: 21 QFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKL-EAEGVPEVSEK 79
Q ++ + + ++V+ F W P C +M+EV+ +A+++ + + L + VP+ ++
Sbjct: 13 QVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKVKNFAVIYLVDITEVPDFNKM 72
Query: 80 YEISSVPTFLFFKNSQKI 97
YE+ T +FF ++ I
Sbjct: 73 YELYDPCTVMFFFRNKHI 90
>gi|215272376 thioredoxin-like 4B [Homo sapiens]
Length = 149
Score = 38.9 bits (89), Expect = 0.007
Identities = 24/108 (22%), Positives = 59/108 (54%), Gaps = 7/108 (6%)
Query: 18 SAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKL-EAEGVPEV 76
S + ++ ++ A+ +LV+ F P C Q+++++++ + +L +++ + L + +
Sbjct: 10 SKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYLVDVDQTAVY 69
Query: 77 SEKYEISSVPTFLFFKNSQ--KIDRLDGAHAPELTKKVQRHASSGSFL 122
++ ++IS +P+ +FF N Q K+D +P+ TK V + F+
Sbjct: 70 TQYFDISYIPSTVFFFNGQHMKVD----YGSPDHTKFVGSFKTKQDFI 113
>gi|214832254 thioredoxin-like 4B [Homo sapiens]
Length = 149
Score = 38.9 bits (89), Expect = 0.007
Identities = 24/108 (22%), Positives = 59/108 (54%), Gaps = 7/108 (6%)
Query: 18 SAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKL-EAEGVPEV 76
S + ++ ++ A+ +LV+ F P C Q+++++++ + +L +++ + L + +
Sbjct: 10 SKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYLVDVDQTAVY 69
Query: 77 SEKYEISSVPTFLFFKNSQ--KIDRLDGAHAPELTKKVQRHASSGSFL 122
++ ++IS +P+ +FF N Q K+D +P+ TK V + F+
Sbjct: 70 TQYFDISYIPSTVFFFNGQHMKVD----YGSPDHTKFVGSFKTKQDFI 113
>gi|8923475 thioredoxin-like 4B [Homo sapiens]
Length = 149
Score = 38.9 bits (89), Expect = 0.007
Identities = 24/108 (22%), Positives = 59/108 (54%), Gaps = 7/108 (6%)
Query: 18 SAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKL-EAEGVPEV 76
S + ++ ++ A+ +LV+ F P C Q+++++++ + +L +++ + L + +
Sbjct: 10 SKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYLVDVDQTAVY 69
Query: 77 SEKYEISSVPTFLFFKNSQ--KIDRLDGAHAPELTKKVQRHASSGSFL 122
++ ++IS +P+ +FF N Q K+D +P+ TK V + F+
Sbjct: 70 TQYFDISYIPSTVFFFNGQHMKVD----YGSPDHTKFVGSFKTKQDFI 113
>gi|88758594 phosducin-like [Homo sapiens]
Length = 301
Score = 38.1 bits (87), Expect = 0.011
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 13 VEEVGSAGQFEELLRLKAKSLLV-VHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAE 71
V E+ S F +++ + KS+++ VH + P MN M LA E P V F K+++
Sbjct: 161 VFEISSGEGFLDMIDKEQKSIVIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFCKVKS- 219
Query: 72 GVPEVSEKYEISSVPTFLFFKNSQKI 97
V S ++ +++P L +K + I
Sbjct: 220 SVIGASSQFTRNALPALLIYKGGELI 245
>gi|54633317 thioredoxin domain containing 11 [Homo sapiens]
Length = 958
Score = 37.7 bits (86), Expect = 0.015
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
Query: 22 FEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAE-GVPEVSEKY 80
F E++ K LL+ ++APW C +N + +LA+ LP +F + ++ ++
Sbjct: 673 FWEVVLQKQDVLLL--YYAPWCGFCPSLNHIFIQLARNLPMDTFTVARIDVSQNDLPWEF 730
Query: 81 EISSVPTFLFFKNSQK 96
+ +PT LFF ++K
Sbjct: 731 MVDRLPTVLFFPCNRK 746
>gi|18104959 thioredoxin domain containing 9 [Homo sapiens]
Length = 226
Score = 37.4 bits (85), Expect = 0.019
Identities = 20/75 (26%), Positives = 37/75 (49%)
Query: 28 LKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAEGVPEVSEKYEISSVPT 87
+K +V HF+ +C ++ +A L+K+ + F+KL E P + E+ I +PT
Sbjct: 86 VKESENVVCHFYRDSTFRCKILDRHLAILSKKHLETKFLKLNVEKAPFLCERLHIKVIPT 145
Query: 88 FLFFKNSQKIDRLDG 102
K+ + D + G
Sbjct: 146 LALLKDGKTQDYVVG 160
>gi|151101292 thioredoxin domain containing 1 [Homo sapiens]
Length = 280
Score = 37.0 bits (84), Expect = 0.025
Identities = 18/64 (28%), Positives = 36/64 (56%), Gaps = 4/64 (6%)
Query: 35 VVHFWAPWAPQCAQMN---EVMAELAKELPQVSFVKLEAEGVPEVSEKYEISSVPTFLFF 91
++ F+APW P C + E AE ++L +V+ K++ P +S ++ I+++PT
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAEWGEDL-EVNIAKVDVTEQPGLSGRFIITALPTIYHC 106
Query: 92 KNSQ 95
K+ +
Sbjct: 107 KDGE 110
>gi|51944950 phosducin-like 2 [Homo sapiens]
Length = 241
Score = 37.0 bits (84), Expect = 0.025
Identities = 19/83 (22%), Positives = 38/83 (45%), Gaps = 3/83 (3%)
Query: 13 VEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAEG 72
+ E+ E+ + +++H + P C +N+ ++ LA++ P+ FVK
Sbjct: 92 LREISGNQYVNEVTNAEEDVWVIIHLYRSSIPMCLLVNQHLSLLARKFPETKFVKAI--- 148
Query: 73 VPEVSEKYEISSVPTFLFFKNSQ 95
V + Y + +PT +KN Q
Sbjct: 149 VNSCIQHYHDNCLPTIFVYKNGQ 171
>gi|52487191 thioredoxin domain containing 4 (endoplasmic reticulum)
[Homo sapiens]
Length = 406
Score = 36.2 bits (82), Expect = 0.042
Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 7/79 (8%)
Query: 28 LKAKSLLVVHFWAPWAPQCAQMNEVMAE----LAKELP---QVSFVKLEAEGVPEVSEKY 80
L + +V+F+A W ++ + E + +E P QV F +++ + +++++Y
Sbjct: 43 LNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRY 102
Query: 81 EISSVPTFLFFKNSQKIDR 99
IS PT F+N + R
Sbjct: 103 RISKYPTLKLFRNGMMMKR 121
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,139,477
Number of Sequences: 37866
Number of extensions: 534342
Number of successful extensions: 1314
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 1254
Number of HSP's gapped (non-prelim): 78
length of query: 335
length of database: 18,247,518
effective HSP length: 103
effective length of query: 232
effective length of database: 14,347,320
effective search space: 3328578240
effective search space used: 3328578240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.