Guide to the Human Genome
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Search of human proteins with 95091988

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
sapiens]
         (765 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi...  1509   0.0  
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi...  1425   0.0  
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]  1014   0.0  
gi|40255080 hypothetical protein LOC158763 [Homo sapiens]             284   2e-76
gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]              98   3e-20
gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b ...    97   6e-20
gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a ...    97   6e-20
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]             96   1e-19
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]           96   1e-19
gi|56119110 family with sequence similarity 13, member A1 isofor...    95   2e-19
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa...    94   5e-19
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa...    94   5e-19
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa...    94   5e-19
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]           93   1e-18
gi|156119615 myosin IXA [Homo sapiens]                                 92   1e-18
gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]         92   2e-18
gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]         92   2e-18
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                91   3e-18
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]             91   5e-18
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]            90   7e-18
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]           90   9e-18
gi|215820652 StAR-related lipid transfer (START) domain containi...    90   9e-18
gi|215820650 StAR-related lipid transfer (START) domain containi...    90   9e-18
gi|31543659 StAR-related lipid transfer (START) domain containin...    90   9e-18
gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Hom...    87   8e-17
gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Hom...    87   8e-17
gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [H...    87   8e-17
gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]            87   8e-17
gi|41281907 StAR-related lipid transfer (START) domain containin...    84   4e-16
gi|16445031 StAR-related lipid transfer (START) domain containin...    84   4e-16

>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
           sapiens]
          Length = 765

 Score = 1509 bits (3907), Expect = 0.0
 Identities = 765/765 (100%), Positives = 765/765 (100%)

Query: 1   MSAQSLLHSVFSCSSPASSSAASAKGFSKRKLRQTRSLDPALIGGCGSDEAGAEGSARGA 60
           MSAQSLLHSVFSCSSPASSSAASAKGFSKRKLRQTRSLDPALIGGCGSDEAGAEGSARGA
Sbjct: 1   MSAQSLLHSVFSCSSPASSSAASAKGFSKRKLRQTRSLDPALIGGCGSDEAGAEGSARGA 60

Query: 61  TAGRLYSPSLPAESLGPRLASSSRGPPPRATRLPPPGPLCSSFSTPSTPQEKSPSGSFHF 120
           TAGRLYSPSLPAESLGPRLASSSRGPPPRATRLPPPGPLCSSFSTPSTPQEKSPSGSFHF
Sbjct: 61  TAGRLYSPSLPAESLGPRLASSSRGPPPRATRLPPPGPLCSSFSTPSTPQEKSPSGSFHF 120

Query: 121 DYEVPLGRGGLKKSMAWDLPSVLAGPASSRSASSILCSSGGGPNGIFASPRRWLQQRKFQ 180
           DYEVPLGRGGLKKSMAWDLPSVLAGPASSRSASSILCSSGGGPNGIFASPRRWLQQRKFQ
Sbjct: 121 DYEVPLGRGGLKKSMAWDLPSVLAGPASSRSASSILCSSGGGPNGIFASPRRWLQQRKFQ 180

Query: 181 SPPDSRGHPYVVWKSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCD 240
           SPPDSRGHPYVVWKSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCD
Sbjct: 181 SPPDSRGHPYVVWKSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCD 240

Query: 241 LSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDL 300
           LSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDL
Sbjct: 241 LSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDL 300

Query: 301 QRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRG 360
           QRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRG
Sbjct: 301 QRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRG 360

Query: 361 AMSVDSITDLDDNQSRLLEALQLSLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQH 420
           AMSVDSITDLDDNQSRLLEALQLSLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQH
Sbjct: 361 AMSVDSITDLDDNQSRLLEALQLSLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQH 420

Query: 421 LEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPL 480
           LEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPL
Sbjct: 421 LEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPL 480

Query: 481 LTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKD 540
           LTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKD
Sbjct: 481 LTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKD 540

Query: 541 GQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEA 600
           GQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEA
Sbjct: 541 GQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEA 600

Query: 601 LFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNK 660
           LFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNK
Sbjct: 601 LFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNK 660

Query: 661 ASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPG 720
           ASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPG
Sbjct: 661 ASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPG 720

Query: 721 PRLGKGNWSLASRRWPKQATLLLLHVAWCGALRTFSSSLPYLMFL 765
           PRLGKGNWSLASRRWPKQATLLLLHVAWCGALRTFSSSLPYLMFL
Sbjct: 721 PRLGKGNWSLASRRWPKQATLLLLHVAWCGALRTFSSSLPYLMFL 765


>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
           sapiens]
          Length = 974

 Score = 1425 bits (3690), Expect = 0.0
 Identities = 725/725 (100%), Positives = 725/725 (100%)

Query: 1   MSAQSLLHSVFSCSSPASSSAASAKGFSKRKLRQTRSLDPALIGGCGSDEAGAEGSARGA 60
           MSAQSLLHSVFSCSSPASSSAASAKGFSKRKLRQTRSLDPALIGGCGSDEAGAEGSARGA
Sbjct: 1   MSAQSLLHSVFSCSSPASSSAASAKGFSKRKLRQTRSLDPALIGGCGSDEAGAEGSARGA 60

Query: 61  TAGRLYSPSLPAESLGPRLASSSRGPPPRATRLPPPGPLCSSFSTPSTPQEKSPSGSFHF 120
           TAGRLYSPSLPAESLGPRLASSSRGPPPRATRLPPPGPLCSSFSTPSTPQEKSPSGSFHF
Sbjct: 61  TAGRLYSPSLPAESLGPRLASSSRGPPPRATRLPPPGPLCSSFSTPSTPQEKSPSGSFHF 120

Query: 121 DYEVPLGRGGLKKSMAWDLPSVLAGPASSRSASSILCSSGGGPNGIFASPRRWLQQRKFQ 180
           DYEVPLGRGGLKKSMAWDLPSVLAGPASSRSASSILCSSGGGPNGIFASPRRWLQQRKFQ
Sbjct: 121 DYEVPLGRGGLKKSMAWDLPSVLAGPASSRSASSILCSSGGGPNGIFASPRRWLQQRKFQ 180

Query: 181 SPPDSRGHPYVVWKSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCD 240
           SPPDSRGHPYVVWKSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCD
Sbjct: 181 SPPDSRGHPYVVWKSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCD 240

Query: 241 LSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDL 300
           LSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDL
Sbjct: 241 LSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDL 300

Query: 301 QRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRG 360
           QRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRG
Sbjct: 301 QRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRG 360

Query: 361 AMSVDSITDLDDNQSRLLEALQLSLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQH 420
           AMSVDSITDLDDNQSRLLEALQLSLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQH
Sbjct: 361 AMSVDSITDLDDNQSRLLEALQLSLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQH 420

Query: 421 LEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPL 480
           LEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPL
Sbjct: 421 LEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPL 480

Query: 481 LTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKD 540
           LTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKD
Sbjct: 481 LTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKD 540

Query: 541 GQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEA 600
           GQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEA
Sbjct: 541 GQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEA 600

Query: 601 LFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNK 660
           LFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNK
Sbjct: 601 LFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNK 660

Query: 661 ASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPG 720
           ASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPG
Sbjct: 661 ASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPG 720

Query: 721 PRLGK 725
           PRLGK
Sbjct: 721 PRLGK 725


>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
          Length = 771

 Score = 1014 bits (2621), Expect = 0.0
 Identities = 522/522 (100%), Positives = 522/522 (100%)

Query: 204 MSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLSCQITIPKDGQKRKKSLRKKLD 263
           MSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLSCQITIPKDGQKRKKSLRKKLD
Sbjct: 1   MSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLSCQITIPKDGQKRKKSLRKKLD 60

Query: 264 SLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDLQRDEQKDASDFVASLLPFGNKRQ 323
           SLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDLQRDEQKDASDFVASLLPFGNKRQ
Sbjct: 61  SLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDLQRDEQKDASDFVASLLPFGNKRQ 120

Query: 324 NKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQL 383
           NKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQL
Sbjct: 121 NKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQL 180

Query: 384 SLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQ 443
           SLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQ
Sbjct: 181 SLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQ 240

Query: 444 LREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGT 503
           LREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGT
Sbjct: 241 LREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGT 300

Query: 504 LQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL 563
           LQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL
Sbjct: 301 LQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL 360

Query: 564 HKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDV 623
           HKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDV
Sbjct: 361 HKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDV 420

Query: 624 VDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNKASSGDISPYDNNSPVLSERSLLA 683
           VDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNKASSGDISPYDNNSPVLSERSLLA
Sbjct: 421 VDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNKASSGDISPYDNNSPVLSERSLLA 480

Query: 684 MQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPGPRLGK 725
           MQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPGPRLGK
Sbjct: 481 MQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPGPRLGK 522


>gi|40255080 hypothetical protein LOC158763 [Homo sapiens]
          Length = 547

 Score =  284 bits (726), Expect = 2e-76
 Identities = 183/489 (37%), Positives = 272/489 (55%), Gaps = 28/489 (5%)

Query: 210 RLRSVPIQSLSELERARLQEVAFYQLQQDCDLS---CQITIPKDGQKRKKSLRKKLDSLG 266
           R + V I SLSELER +LQE A+++L     LS       +P D   R  +L K    L 
Sbjct: 46  RTKMVSIHSLSELERLKLQETAYHELVARHFLSEFKPDRALPID---RPNTLDKWFLIL- 101

Query: 267 KEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDLQRDEQKDASDFVASLLPFGNKRQNKE 326
             + + +    + FG+ L +V+ N+   +   +L    Q + +   A+    G +R N  
Sbjct: 102 --RGQQRAVSHKTFGISLEEVLVNEFTRRKHLELTATMQVEEATGQAA----GRRRGNVV 155

Query: 327 LSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQLSLP 386
                      S   NE   P  P    R  RRGA+SVDS+ +L+D  + LL+ LQLS  
Sbjct: 156 RRVFGRIRRFFSRRRNE---PTLPREFTRRGRRGAVSVDSLAELEDG-ALLLQTLQLSKI 211

Query: 387 AEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLRE 446
           +    ++     +K+SLNPI +Q+P++V++CCQ +EKHGL  VGIF +  S +RVRQLRE
Sbjct: 212 SFPIGQRLLGSKRKMSLNPIAKQIPQVVEACCQFIEKHGLSAVGIFTLEYSVQRVRQLRE 271

Query: 447 EFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQL 506
           EFD+G+DV L++  +VHDVAALLKEF RDM D LL  +LY +F+ T  L+P++QL  LQL
Sbjct: 272 EFDQGLDVVLDDNQNVHDVAALLKEFFRDMKDSLLPDDLYMSFLLTATLKPQDQLSALQL 331

Query: 507 LIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQ 566
           L+YL+PPC+ DTL RLL+ L  +  + +D+I  DGQ V GN+MTS NLA +FG  LL K 
Sbjct: 332 LVYLMPPCHSDTLERLLKALHKITENCEDSIGIDGQLVPGNRMTSTNLALVFGSALLKKG 391

Query: 567 KSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDY 626
           K   +E S ++    +   A + VV+ MI+N++ LF VPP +Q +V   + ++ P+ +D+
Sbjct: 392 KFGKRE-SRKTKLGIDHYVASVNVVRAMIDNWDVLFQVPPHIQRQVAKRVWKSSPEALDF 450

Query: 627 LLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNKASSGDISPYDNNSPVLSERSLLAMQE 686
           + RR   +  S  +   E +       +S ++  A      P D  S           +E
Sbjct: 451 IRRRNLRKIQSARIKMEEDALLSDPVETSAEARAAVLAQSKPSDEGS----------SEE 500

Query: 687 DAAPGGSEK 695
            A P G+ +
Sbjct: 501 PAVPSGTAR 509


>gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]
          Length = 439

 Score = 97.8 bits (242), Expect = 3e-20
 Identities = 52/160 (32%), Positives = 90/160 (56%), Gaps = 11/160 (6%)

Query: 404 NPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVH 463
           NP    +P ++     +L+ H L T GIFR  ++ + VR+++++++ G+ V  ++ + +H
Sbjct: 253 NPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELH 312

Query: 464 DVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLL 523
             A +LK FLR++P+PLLT +LY   +  L ++  +++     ++  LP  N   L  L 
Sbjct: 313 LPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLT 372

Query: 524 QFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL 563
            FL  ++ H+D            NKMT+ NLA +FGPNLL
Sbjct: 373 AFLVQISAHSDQ-----------NKMTNTNLAVVFGPNLL 401


>gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b
           [Homo sapiens]
          Length = 1075

 Score = 97.1 bits (240), Expect = 6e-20
 Identities = 63/206 (30%), Positives = 108/206 (52%), Gaps = 23/206 (11%)

Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGID--VSLEEEHSVHDVAA 467
           +P +V+SC +++  +GLQ  GIFRV  S+  V  ++  F+RG D  V  + E  ++ VA 
Sbjct: 495 IPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAG 554

Query: 468 LLKEFLRDMPDPLLTRELYTAFINTLLLE-PEEQLGTLQLLIYLLPPCNCDTLHRLLQFL 526
           +LK + R + +PL  +E +   I+T+ LE P E++  +Q ++  LP      +  L  FL
Sbjct: 555 VLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFL 614

Query: 527 SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTA 586
           + +++++D+N+           M   NLA  FGP L+H     D    V   A   E   
Sbjct: 615 NHLSQYSDENM-----------MDPYNLAICFGPTLMHIPDGQD---PVSCQAHINE--- 657

Query: 587 IIAVVQKMIENYEALFMVPPDLQNEV 612
              V++ +I ++EA+F  P +L+  V
Sbjct: 658 ---VIKTIIIHHEAIFPSPRELEGPV 680


>gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a
           [Homo sapiens]
          Length = 1099

 Score = 97.1 bits (240), Expect = 6e-20
 Identities = 63/206 (30%), Positives = 108/206 (52%), Gaps = 23/206 (11%)

Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGID--VSLEEEHSVHDVAA 467
           +P +V+SC +++  +GLQ  GIFRV  S+  V  ++  F+RG D  V  + E  ++ VA 
Sbjct: 519 IPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAG 578

Query: 468 LLKEFLRDMPDPLLTRELYTAFINTLLLE-PEEQLGTLQLLIYLLPPCNCDTLHRLLQFL 526
           +LK + R + +PL  +E +   I+T+ LE P E++  +Q ++  LP      +  L  FL
Sbjct: 579 VLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFL 638

Query: 527 SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTA 586
           + +++++D+N+           M   NLA  FGP L+H     D    V   A   E   
Sbjct: 639 NHLSQYSDENM-----------MDPYNLAICFGPTLMHIPDGQD---PVSCQAHINE--- 681

Query: 587 IIAVVQKMIENYEALFMVPPDLQNEV 612
              V++ +I ++EA+F  P +L+  V
Sbjct: 682 ---VIKTIIIHHEAIFPSPRELEGPV 704


>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
          Length = 459

 Score = 96.3 bits (238), Expect = 1e-19
 Identities = 58/196 (29%), Positives = 98/196 (50%), Gaps = 22/196 (11%)

Query: 411 PRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRG---IDVSLEEEHSVHDVAA 467
           P +VD C + +E  GL + G++RV      +  ++  FDR     D+S+     ++ +  
Sbjct: 282 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 341

Query: 468 LLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFL 526
            LK + RD+P PL+T + Y  FI +  +++P+EQL TL   + LLPP +C+TL  L+  L
Sbjct: 342 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 401

Query: 527 SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTA 586
             V  H  +N+           M + NL  +FGP L+   +       + + A   +   
Sbjct: 402 KRVTLHEKENL-----------MNAENLGIVFGPTLMRSPE-------LDAMAALNDIRY 443

Query: 587 IIAVVQKMIENYEALF 602
              VV+ +I+N + LF
Sbjct: 444 QRLVVELLIKNEDILF 459


>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
          Length = 433

 Score = 96.3 bits (238), Expect = 1e-19
 Identities = 58/196 (29%), Positives = 98/196 (50%), Gaps = 22/196 (11%)

Query: 411 PRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRG---IDVSLEEEHSVHDVAA 467
           P +VD C + +E  GL + G++RV      +  ++  FDR     D+S+     ++ +  
Sbjct: 256 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 315

Query: 468 LLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFL 526
            LK + RD+P PL+T + Y  FI +  +++P+EQL TL   + LLPP +C+TL  L+  L
Sbjct: 316 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 375

Query: 527 SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTA 586
             V  H  +N+           M + NL  +FGP L+   +       + + A   +   
Sbjct: 376 KRVTLHEKENL-----------MNAENLGIVFGPTLMRSPE-------LDAMAALNDIRY 417

Query: 587 IIAVVQKMIENYEALF 602
              VV+ +I+N + LF
Sbjct: 418 QRLVVELLIKNEDILF 433


>gi|56119110 family with sequence similarity 13, member A1 isoform a
           [Homo sapiens]
          Length = 1023

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 71/211 (33%), Positives = 104/211 (49%), Gaps = 27/211 (12%)

Query: 401 LSLNPIYRQ------VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDV 454
           +SL  + RQ      +P +V +  ++L +HGL   G+FRV  + K V QLR +F+ G+ V
Sbjct: 43  VSLQELERQGLTENGIPAVVWNIVEYLTQHGLTQEGLFRVNGNVKVVEQLRLKFESGVPV 102

Query: 455 SLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTLL-LEPEEQLGTLQLLIYLLPP 513
            L ++  V   A+LLK FLR++PD L+T  L   FI        + Q  +L+ LI  LP 
Sbjct: 103 ELGKDGDVCSAASLLKLFLRELPDSLITSALQPRFIQLFQDGRNDVQESSLRDLIKELPD 162

Query: 514 CNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEF 573
            +   L  L QFL+ VA+H              N+M   NLAT+FGPN  H     +   
Sbjct: 163 THYCLLKYLCQFLTKVAKHH-----------VQNRMNVHNLATVFGPNCFHVPPGLE--- 208

Query: 574 SVQSSARAEESTAIIAVVQKMIENYEALFMV 604
                   +E      ++ K++ENY  LF V
Sbjct: 209 ------GMKEQDLCNKIMAKILENYNTLFEV 233


>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
           sapiens]
          Length = 653

 Score = 94.0 bits (232), Expect = 5e-19
 Identities = 65/209 (31%), Positives = 106/209 (50%), Gaps = 25/209 (11%)

Query: 408 RQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAA 467
           R  P LV+ C   + + GL+  G+FR+      V++L++ FD G   S +    VH VA+
Sbjct: 55  RLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVAS 114

Query: 468 LLKEFLRDMPDPLLTRELYTAFIN-TLLLEPEEQLGTLQLL--IYLLPPCNCDTLHRLLQ 524
           LLK +LR++P+P++    Y  F++   LL  EE+ G  +L   +  LP  N + L  + +
Sbjct: 115 LLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICR 174

Query: 525 FLSIVARHADDNISKDGQEVTG-NKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEE 583
           FL  V            Q  +G NKM+  NLAT+FGPN+L  +        V+      E
Sbjct: 175 FLDEV------------QSYSGVNKMSVQNLATVFGPNILRPK--------VEDPLTIME 214

Query: 584 STAII-AVVQKMIENYEALFMVPPDLQNE 611
            T ++  ++  MI  ++ LF    +LQ++
Sbjct: 215 GTVVVQQLMSVMISKHDCLFPKDAELQSK 243


>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
           sapiens]
          Length = 655

 Score = 94.0 bits (232), Expect = 5e-19
 Identities = 65/209 (31%), Positives = 106/209 (50%), Gaps = 25/209 (11%)

Query: 408 RQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAA 467
           R  P LV+ C   + + GL+  G+FR+      V++L++ FD G   S +    VH VA+
Sbjct: 57  RLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVAS 116

Query: 468 LLKEFLRDMPDPLLTRELYTAFIN-TLLLEPEEQLGTLQLL--IYLLPPCNCDTLHRLLQ 524
           LLK +LR++P+P++    Y  F++   LL  EE+ G  +L   +  LP  N + L  + +
Sbjct: 117 LLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICR 176

Query: 525 FLSIVARHADDNISKDGQEVTG-NKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEE 583
           FL  V            Q  +G NKM+  NLAT+FGPN+L  +        V+      E
Sbjct: 177 FLDEV------------QSYSGVNKMSVQNLATVFGPNILRPK--------VEDPLTIME 216

Query: 584 STAII-AVVQKMIENYEALFMVPPDLQNE 611
            T ++  ++  MI  ++ LF    +LQ++
Sbjct: 217 GTVVVQQLMSVMISKHDCLFPKDAELQSK 245


>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
           sapiens]
          Length = 748

 Score = 94.0 bits (232), Expect = 5e-19
 Identities = 65/209 (31%), Positives = 106/209 (50%), Gaps = 25/209 (11%)

Query: 408 RQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAA 467
           R  P LV+ C   + + GL+  G+FR+      V++L++ FD G   S +    VH VA+
Sbjct: 150 RLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVAS 209

Query: 468 LLKEFLRDMPDPLLTRELYTAFIN-TLLLEPEEQLGTLQLL--IYLLPPCNCDTLHRLLQ 524
           LLK +LR++P+P++    Y  F++   LL  EE+ G  +L   +  LP  N + L  + +
Sbjct: 210 LLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICR 269

Query: 525 FLSIVARHADDNISKDGQEVTG-NKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEE 583
           FL  V            Q  +G NKM+  NLAT+FGPN+L  +        V+      E
Sbjct: 270 FLDEV------------QSYSGVNKMSVQNLATVFGPNILRPK--------VEDPLTIME 309

Query: 584 STAII-AVVQKMIENYEALFMVPPDLQNE 611
            T ++  ++  MI  ++ LF    +LQ++
Sbjct: 310 GTVVVQQLMSVMISKHDCLFPKDAELQSK 338


>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
          Length = 1958

 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 55/166 (33%), Positives = 92/166 (55%), Gaps = 15/166 (9%)

Query: 408  RQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRG---IDVSLEEEHSVHD 464
            R +P +VD CC+ +E+ GL+  GI+RV  +   +  ++EE ++G   ID+  ++   ++ 
Sbjct: 1159 RYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLNV 1218

Query: 465  VAALLKEFLRDMPDPLLTRELYTAFINTLLLE-PEEQLGTLQLLIYLLPPCNCDTLHRLL 523
            +++LLK F R +P+PL T + Y  FI     E P ++L TL+ LI+ LP  + +TL  L 
Sbjct: 1219 ISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETLKFLS 1278

Query: 524  QFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSS 569
              L  VA +++            NKM   NLA +FGP L+   + +
Sbjct: 1279 AHLKTVAENSEK-----------NKMEPRNLAIVFGPTLVRTSEDN 1313


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score = 92.4 bits (228), Expect = 1e-18
 Identities = 57/194 (29%), Positives = 106/194 (54%), Gaps = 14/194 (7%)

Query: 408  RQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAA 467
            R VP +V+    ++E HGL T GI+R   S  ++++LR+  D   +    +++++H +A+
Sbjct: 2073 RTVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAESVNLDDYNIHVIAS 2132

Query: 468  LLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFL 526
            + K++LRD+P+PL+T ELY  F+  + L E +E +  +  +I  L   + +TL RL+  L
Sbjct: 2133 VFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQLSRTHLNTLERLIFHL 2192

Query: 527  SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTA 586
              +A   D            N+M++  LA +F P +L    ++D   SVQ  ++   +T 
Sbjct: 2193 VRIALQEDT-----------NRMSANALAIVFAPCILRCPDTTDPLQSVQDISKT--TTC 2239

Query: 587  IIAVVQKMIENYEA 600
            +  +V + +  Y+A
Sbjct: 2240 VELIVVEQMNKYKA 2253


>gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]
          Length = 1528

 Score = 91.7 bits (226), Expect = 2e-18
 Identities = 65/211 (30%), Positives = 100/211 (47%), Gaps = 23/211 (10%)

Query: 410  VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469
            +P+ +    ++L  H L  VG+FR    K R++ LR+  +  ID    E  S +DVA +L
Sbjct: 1091 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 1150

Query: 470  KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528
            K++ RD+P+PL+T +L   F+      P++Q L  ++  I LLP  N + L  LL FLS 
Sbjct: 1151 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 1210

Query: 529  VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH-----KQKSSDKEFSVQSS----- 578
            V              V  N+MT  NLA    P+L H     ++ SS +    + S     
Sbjct: 1211 VT-----------AAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPD 1259

Query: 579  -ARAEESTAIIAVVQKMIENYEALFMVPPDL 608
                 E+ A    +  MI   + LF VP ++
Sbjct: 1260 QKDLNENLAATQGLAHMIAECKKLFQVPEEM 1290


>gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]
          Length = 1091

 Score = 91.7 bits (226), Expect = 2e-18
 Identities = 65/211 (30%), Positives = 100/211 (47%), Gaps = 23/211 (10%)

Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469
           +P+ +    ++L  H L  VG+FR    K R++ LR+  +  ID    E  S +DVA +L
Sbjct: 654 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 713

Query: 470 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528
           K++ RD+P+PL+T +L   F+      P++Q L  ++  I LLP  N + L  LL FLS 
Sbjct: 714 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 773

Query: 529 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH-----KQKSSDKEFSVQSS----- 578
           V              V  N+MT  NLA    P+L H     ++ SS +    + S     
Sbjct: 774 VT-----------AAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPD 822

Query: 579 -ARAEESTAIIAVVQKMIENYEALFMVPPDL 608
                E+ A    +  MI   + LF VP ++
Sbjct: 823 QKDLNENLAATQGLAHMIAECKKLFQVPEEM 853


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 91.3 bits (225), Expect = 3e-18
 Identities = 75/241 (31%), Positives = 123/241 (51%), Gaps = 22/241 (9%)

Query: 403 LNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHS- 461
           L  + R++   +++C   L   G++  G+FR+ +    +++L++        SLEE  S 
Sbjct: 282 LQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPH-SLEEFCSD 340

Query: 462 VHDVAALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLH 520
            H VA  LK +LR++P+PL+T +LY  ++    L EP  +L  LQ +   LPP N   L 
Sbjct: 341 PHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLR 400

Query: 521 RLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL-HKQKSSDKEFSVQSSA 579
            L++FL+ +A         + QEV  NKMT  N+A + GPNLL   +K  D+    Q  A
Sbjct: 401 YLMKFLARLA---------EEQEV--NKMTPSNIAIVLGPNLLWPPEKEGDQ---AQLDA 446

Query: 580 RAEESTAIIAVVQKMIENYEALFMVPPDLQNEV--LISLLETDPDVVDYLLRRKASQSSS 637
            +  S  ++ VV+ +I++ + LF  P D+   V  L S +     V D L   +   ++ 
Sbjct: 447 ASVSSIQVVGVVEALIQSADTLF--PGDINFNVSGLFSAVTLQDTVSDRLASEELPSTAV 504

Query: 638 P 638
           P
Sbjct: 505 P 505


>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
          Length = 698

 Score = 90.5 bits (223), Expect = 5e-18
 Identities = 63/202 (31%), Positives = 100/202 (49%), Gaps = 23/202 (11%)

Query: 408 RQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAA 467
           R  P LV+ C   + + GL   G+FR+      VR L++ FD G     +    VH VA+
Sbjct: 170 RLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVAS 229

Query: 468 LLKEFLRDMPDPLLTRELYTAFIN-TLLLEPEEQLGTLQLL--IYLLPPCNCDTLHRLLQ 524
           LLK +LR++P+P++    Y  F++   LL  +E  GTL+L   +  LP  N + L  + +
Sbjct: 230 LLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICK 289

Query: 525 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 584
           FL  V  +++            NKM+  NLAT+FGPN+L  Q        V+      E 
Sbjct: 290 FLDEVQAYSN-----------VNKMSVQNLATVFGPNILRPQ--------VEDPVTIMEG 330

Query: 585 TAIIA-VVQKMIENYEALFMVP 605
           T+++  ++  +I  +  LF  P
Sbjct: 331 TSLVQHLMTVLIRKHSQLFTAP 352


>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
          Length = 846

 Score = 90.1 bits (222), Expect = 7e-18
 Identities = 50/162 (30%), Positives = 86/162 (53%), Gaps = 13/162 (8%)

Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLR--EEFDRGIDVSLEEEHSVHDVAA 467
           VP+ V  C +H+E+HGL   GI+RV  +   +++LR     D  +D++  +   +H +  
Sbjct: 669 VPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITG 728

Query: 468 LLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLS 527
            LK F R++P+PL T   +  F+N +  EP +++  ++ LI  LP  N DT+  L + L 
Sbjct: 729 ALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLR 788

Query: 528 IVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSS 569
            V  + +            N+MT  ++A +FGP LL  +K +
Sbjct: 789 RVIENGEK-----------NRMTYQSIAIVFGPTLLKPEKET 819


>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
          Length = 1397

 Score = 89.7 bits (221), Expect = 9e-18
 Identities = 56/166 (33%), Positives = 94/166 (56%), Gaps = 15/166 (9%)

Query: 408 RQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGI-DVSLEEE--HSVHD 464
           ++VP +V +CC+ +E  GL++ GI+RV  +   V  L+E+ +RG  D++L++E    ++ 
Sbjct: 823 QRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLNV 882

Query: 465 VAALLKEFLRDMPDPLLTRELYTAFINTLLLE-PEEQLGTLQLLIYLLPPCNCDTLHRLL 523
           +++LLK F R +P+PL T + Y  FI    +E   E++ TL+ LI  LP    +TL  L+
Sbjct: 883 ISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHYYETLKFLV 942

Query: 524 QFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSS 569
             L  +A H++            NKM   NLA +FGP L+   + +
Sbjct: 943 GHLKTIADHSEK-----------NKMEPRNLALVFGPTLVRTSEDN 977


>gi|215820652 StAR-related lipid transfer (START) domain containing
           8 isoform b [Homo sapiens]
          Length = 1023

 Score = 89.7 bits (221), Expect = 9e-18
 Identities = 63/211 (29%), Positives = 98/211 (46%), Gaps = 24/211 (11%)

Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469
           +P+ +    ++L    L  VGIFR    K R++ LR+  +   D    E  S +DVA LL
Sbjct: 585 LPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLL 644

Query: 470 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528
           K++ RD+P+P+ T +L T F+    L P++Q L   Q    LLP  N + L  LL FLS 
Sbjct: 645 KQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSD 704

Query: 529 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSAR-------- 580
           +A   +            N+MT+ NLA    P++ H   S     S +  ++        
Sbjct: 705 IASAEE------------NQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPG 752

Query: 581 ---AEESTAIIAVVQKMIENYEALFMVPPDL 608
                ++ A    +  MI + + LF VP D+
Sbjct: 753 PRDLSDNMAATQGLSHMISDCKKLFQVPQDM 783


>gi|215820650 StAR-related lipid transfer (START) domain containing
           8 isoform a [Homo sapiens]
          Length = 1103

 Score = 89.7 bits (221), Expect = 9e-18
 Identities = 63/211 (29%), Positives = 98/211 (46%), Gaps = 24/211 (11%)

Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469
           +P+ +    ++L    L  VGIFR    K R++ LR+  +   D    E  S +DVA LL
Sbjct: 665 LPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLL 724

Query: 470 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528
           K++ RD+P+P+ T +L T F+    L P++Q L   Q    LLP  N + L  LL FLS 
Sbjct: 725 KQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSD 784

Query: 529 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSAR-------- 580
           +A   +            N+MT+ NLA    P++ H   S     S +  ++        
Sbjct: 785 IASAEE------------NQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPG 832

Query: 581 ---AEESTAIIAVVQKMIENYEALFMVPPDL 608
                ++ A    +  MI + + LF VP D+
Sbjct: 833 PRDLSDNMAATQGLSHMISDCKKLFQVPQDM 863


>gi|31543659 StAR-related lipid transfer (START) domain containing 8
           isoform b [Homo sapiens]
          Length = 1023

 Score = 89.7 bits (221), Expect = 9e-18
 Identities = 63/211 (29%), Positives = 98/211 (46%), Gaps = 24/211 (11%)

Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469
           +P+ +    ++L    L  VGIFR    K R++ LR+  +   D    E  S +DVA LL
Sbjct: 585 LPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLL 644

Query: 470 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528
           K++ RD+P+P+ T +L T F+    L P++Q L   Q    LLP  N + L  LL FLS 
Sbjct: 645 KQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSD 704

Query: 529 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSAR-------- 580
           +A   +            N+MT+ NLA    P++ H   S     S +  ++        
Sbjct: 705 IASAEE------------NQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPG 752

Query: 581 ---AEESTAIIAVVQKMIENYEALFMVPPDL 608
                ++ A    +  MI + + LF VP D+
Sbjct: 753 PRDLSDNMAATQGLSHMISDCKKLFQVPQDM 783


>gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Homo
           sapiens]
          Length = 622

 Score = 86.7 bits (213), Expect = 8e-17
 Identities = 81/260 (31%), Positives = 113/260 (43%), Gaps = 36/260 (13%)

Query: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVH--DVA 466
           QVP ++ +    LEK GL   GI RV  S+ RV+ L ++ +R     L     VH  D +
Sbjct: 287 QVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDAS 346

Query: 467 ALLKEFLRDMPDPLLTRELYTAF-INTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525
            LLK F+R +P PLLT E   AF +   +   +++L  L LLI +LP  N + L  LL+F
Sbjct: 347 DLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEF 406

Query: 526 L-SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 584
           L  +VAR               NKMT  N++T+  PNL   Q    K    +    AE +
Sbjct: 407 LRKVVAREQH------------NKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGA 454

Query: 585 TAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSE 644
                VVQ M+   + L+ V   L  +V                 RK + SSS      +
Sbjct: 455 A---EVVQIMVHYQDLLWTVASFLVAQV-----------------RKLNDSSSRRPQLCD 494

Query: 645 VSFSVGGRHSSTDSNKASSG 664
                  R    D +KA  G
Sbjct: 495 AGLKTWLRRMHADRDKAGDG 514


>gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo
           sapiens]
          Length = 622

 Score = 86.7 bits (213), Expect = 8e-17
 Identities = 81/260 (31%), Positives = 113/260 (43%), Gaps = 36/260 (13%)

Query: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVH--DVA 466
           QVP ++ +    LEK GL   GI RV  S+ RV+ L ++ +R     L     VH  D +
Sbjct: 287 QVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDAS 346

Query: 467 ALLKEFLRDMPDPLLTRELYTAF-INTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525
            LLK F+R +P PLLT E   AF +   +   +++L  L LLI +LP  N + L  LL+F
Sbjct: 347 DLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEF 406

Query: 526 L-SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 584
           L  +VAR               NKMT  N++T+  PNL   Q    K    +    AE +
Sbjct: 407 LRKVVAREQH------------NKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGA 454

Query: 585 TAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSE 644
                VVQ M+   + L+ V   L  +V                 RK + SSS      +
Sbjct: 455 A---EVVQIMVHYQDLLWTVASFLVAQV-----------------RKLNDSSSRRPQLCD 494

Query: 645 VSFSVGGRHSSTDSNKASSG 664
                  R    D +KA  G
Sbjct: 495 AGLKTWLRRMHADRDKAGDG 514


>gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [Homo
           sapiens]
          Length = 622

 Score = 86.7 bits (213), Expect = 8e-17
 Identities = 81/260 (31%), Positives = 113/260 (43%), Gaps = 36/260 (13%)

Query: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVH--DVA 466
           QVP ++ +    LEK GL   GI RV  S+ RV+ L ++ +R     L     VH  D +
Sbjct: 287 QVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDAS 346

Query: 467 ALLKEFLRDMPDPLLTRELYTAF-INTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525
            LLK F+R +P PLLT E   AF +   +   +++L  L LLI +LP  N + L  LL+F
Sbjct: 347 DLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEF 406

Query: 526 L-SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 584
           L  +VAR               NKMT  N++T+  PNL   Q    K    +    AE +
Sbjct: 407 LRKVVAREQH------------NKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGA 454

Query: 585 TAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSE 644
                VVQ M+   + L+ V   L  +V                 RK + SSS      +
Sbjct: 455 A---EVVQIMVHYQDLLWTVASFLVAQV-----------------RKLNDSSSRRPQLCD 494

Query: 645 VSFSVGGRHSSTDSNKASSG 664
                  R    D +KA  G
Sbjct: 495 AGLKTWLRRMHADRDKAGDG 514


>gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]
          Length = 663

 Score = 86.7 bits (213), Expect = 8e-17
 Identities = 67/211 (31%), Positives = 104/211 (49%), Gaps = 25/211 (11%)

Query: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSV--HDVA 466
           ++P +       +E+ GL+T G+ R+  +  R++ L +E +           SV  HD A
Sbjct: 341 RIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAA 400

Query: 467 ALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525
           +LLK F+R++P PLL+ E   AF     L   ++QL  L LL+ LLP  N DTL  LL+F
Sbjct: 401 SLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEF 460

Query: 526 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQ----KSSDKEFSVQSSARA 581
           L  V     DN  K       NKMT +N+A +  PNL        KSS++   V ++  A
Sbjct: 461 LQRVI----DNKEK-------NKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTA 509

Query: 582 EESTAIIAVVQKMIENYEALFMVPPDLQNEV 612
                    +  +I+  + L+ +P  + N+V
Sbjct: 510 N-------TMHLLIKYQKLLWTIPKFIVNQV 533


>gi|41281907 StAR-related lipid transfer (START) domain containing
           13 isoform beta [Homo sapiens]
          Length = 1105

 Score = 84.3 bits (207), Expect = 4e-16
 Identities = 65/225 (28%), Positives = 111/225 (49%), Gaps = 28/225 (12%)

Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRV---RQLREEFDRGIDVSLEEEHSVHDVA 466
           +P+ +    ++L  + L  VG+FR    K R+   RQ+ E F   ++    E+ S +DVA
Sbjct: 668 LPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPENVNY---EDQSAYDVA 724

Query: 467 ALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525
            ++K+F RD+P+PL T +L   F++    +  E++L  +Q  I LL   N + L  LL F
Sbjct: 725 DMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCF 784

Query: 526 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH----KQKSS----DKEFSVQS 577
           L+ V    ++           N+MT +NLA    P+L H    K++SS     K+++   
Sbjct: 785 LNDVVNLVEE-----------NQMTPMNLAVCLAPSLFHLNLLKKESSPRVIQKKYATGK 833

Query: 578 SARAE--ESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETD 620
             + +  E+ A    +  MI   + LF VP +L  +   S +E +
Sbjct: 834 PDQKDLNENLAAAQGLAHMIMECDRLFEVPHELVAQSRNSYVEAE 878


>gi|16445031 StAR-related lipid transfer (START) domain containing
           13 isoform gamma [Homo sapiens]
          Length = 995

 Score = 84.3 bits (207), Expect = 4e-16
 Identities = 65/225 (28%), Positives = 111/225 (49%), Gaps = 28/225 (12%)

Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRV---RQLREEFDRGIDVSLEEEHSVHDVA 466
           +P+ +    ++L  + L  VG+FR    K R+   RQ+ E F   ++    E+ S +DVA
Sbjct: 558 LPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPENVNY---EDQSAYDVA 614

Query: 467 ALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525
            ++K+F RD+P+PL T +L   F++    +  E++L  +Q  I LL   N + L  LL F
Sbjct: 615 DMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCF 674

Query: 526 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH----KQKSS----DKEFSVQS 577
           L+ V    ++           N+MT +NLA    P+L H    K++SS     K+++   
Sbjct: 675 LNDVVNLVEE-----------NQMTPMNLAVCLAPSLFHLNLLKKESSPRVIQKKYATGK 723

Query: 578 SARAE--ESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETD 620
             + +  E+ A    +  MI   + LF VP +L  +   S +E +
Sbjct: 724 PDQKDLNENLAAAQGLAHMIMECDRLFEVPHELVAQSRNSYVEAE 768


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,958,253
Number of Sequences: 37866
Number of extensions: 1675335
Number of successful extensions: 9768
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 126
Number of HSP's successfully gapped in prelim test: 254
Number of HSP's that attempted gapping in prelim test: 8921
Number of HSP's gapped (non-prelim): 894
length of query: 765
length of database: 18,247,518
effective HSP length: 110
effective length of query: 655
effective length of database: 14,082,258
effective search space: 9223878990
effective search space used: 9223878990
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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