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Search of human proteins with 95091988
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
sapiens]
(765 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi... 1509 0.0
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi... 1425 0.0
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens] 1014 0.0
gi|40255080 hypothetical protein LOC158763 [Homo sapiens] 284 2e-76
gi|4757766 Rho GTPase activating protein 1 [Homo sapiens] 98 3e-20
gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b ... 97 6e-20
gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a ... 97 6e-20
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 96 1e-19
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 96 1e-19
gi|56119110 family with sequence similarity 13, member A1 isofor... 95 2e-19
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 94 5e-19
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa... 94 5e-19
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 94 5e-19
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 93 1e-18
gi|156119615 myosin IXA [Homo sapiens] 92 1e-18
gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens] 92 2e-18
gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens] 92 2e-18
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 91 3e-18
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 91 5e-18
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 90 7e-18
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 90 9e-18
gi|215820652 StAR-related lipid transfer (START) domain containi... 90 9e-18
gi|215820650 StAR-related lipid transfer (START) domain containi... 90 9e-18
gi|31543659 StAR-related lipid transfer (START) domain containin... 90 9e-18
gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Hom... 87 8e-17
gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Hom... 87 8e-17
gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [H... 87 8e-17
gi|39932589 Rho GTPase activating protein 18 [Homo sapiens] 87 8e-17
gi|41281907 StAR-related lipid transfer (START) domain containin... 84 4e-16
gi|16445031 StAR-related lipid transfer (START) domain containin... 84 4e-16
>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
sapiens]
Length = 765
Score = 1509 bits (3907), Expect = 0.0
Identities = 765/765 (100%), Positives = 765/765 (100%)
Query: 1 MSAQSLLHSVFSCSSPASSSAASAKGFSKRKLRQTRSLDPALIGGCGSDEAGAEGSARGA 60
MSAQSLLHSVFSCSSPASSSAASAKGFSKRKLRQTRSLDPALIGGCGSDEAGAEGSARGA
Sbjct: 1 MSAQSLLHSVFSCSSPASSSAASAKGFSKRKLRQTRSLDPALIGGCGSDEAGAEGSARGA 60
Query: 61 TAGRLYSPSLPAESLGPRLASSSRGPPPRATRLPPPGPLCSSFSTPSTPQEKSPSGSFHF 120
TAGRLYSPSLPAESLGPRLASSSRGPPPRATRLPPPGPLCSSFSTPSTPQEKSPSGSFHF
Sbjct: 61 TAGRLYSPSLPAESLGPRLASSSRGPPPRATRLPPPGPLCSSFSTPSTPQEKSPSGSFHF 120
Query: 121 DYEVPLGRGGLKKSMAWDLPSVLAGPASSRSASSILCSSGGGPNGIFASPRRWLQQRKFQ 180
DYEVPLGRGGLKKSMAWDLPSVLAGPASSRSASSILCSSGGGPNGIFASPRRWLQQRKFQ
Sbjct: 121 DYEVPLGRGGLKKSMAWDLPSVLAGPASSRSASSILCSSGGGPNGIFASPRRWLQQRKFQ 180
Query: 181 SPPDSRGHPYVVWKSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCD 240
SPPDSRGHPYVVWKSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCD
Sbjct: 181 SPPDSRGHPYVVWKSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCD 240
Query: 241 LSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDL 300
LSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDL
Sbjct: 241 LSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDL 300
Query: 301 QRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRG 360
QRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRG
Sbjct: 301 QRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRG 360
Query: 361 AMSVDSITDLDDNQSRLLEALQLSLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQH 420
AMSVDSITDLDDNQSRLLEALQLSLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQH
Sbjct: 361 AMSVDSITDLDDNQSRLLEALQLSLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQH 420
Query: 421 LEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPL 480
LEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPL
Sbjct: 421 LEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPL 480
Query: 481 LTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKD 540
LTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKD
Sbjct: 481 LTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKD 540
Query: 541 GQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEA 600
GQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEA
Sbjct: 541 GQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEA 600
Query: 601 LFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNK 660
LFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNK
Sbjct: 601 LFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNK 660
Query: 661 ASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPG 720
ASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPG
Sbjct: 661 ASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPG 720
Query: 721 PRLGKGNWSLASRRWPKQATLLLLHVAWCGALRTFSSSLPYLMFL 765
PRLGKGNWSLASRRWPKQATLLLLHVAWCGALRTFSSSLPYLMFL
Sbjct: 721 PRLGKGNWSLASRRWPKQATLLLLHVAWCGALRTFSSSLPYLMFL 765
>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
sapiens]
Length = 974
Score = 1425 bits (3690), Expect = 0.0
Identities = 725/725 (100%), Positives = 725/725 (100%)
Query: 1 MSAQSLLHSVFSCSSPASSSAASAKGFSKRKLRQTRSLDPALIGGCGSDEAGAEGSARGA 60
MSAQSLLHSVFSCSSPASSSAASAKGFSKRKLRQTRSLDPALIGGCGSDEAGAEGSARGA
Sbjct: 1 MSAQSLLHSVFSCSSPASSSAASAKGFSKRKLRQTRSLDPALIGGCGSDEAGAEGSARGA 60
Query: 61 TAGRLYSPSLPAESLGPRLASSSRGPPPRATRLPPPGPLCSSFSTPSTPQEKSPSGSFHF 120
TAGRLYSPSLPAESLGPRLASSSRGPPPRATRLPPPGPLCSSFSTPSTPQEKSPSGSFHF
Sbjct: 61 TAGRLYSPSLPAESLGPRLASSSRGPPPRATRLPPPGPLCSSFSTPSTPQEKSPSGSFHF 120
Query: 121 DYEVPLGRGGLKKSMAWDLPSVLAGPASSRSASSILCSSGGGPNGIFASPRRWLQQRKFQ 180
DYEVPLGRGGLKKSMAWDLPSVLAGPASSRSASSILCSSGGGPNGIFASPRRWLQQRKFQ
Sbjct: 121 DYEVPLGRGGLKKSMAWDLPSVLAGPASSRSASSILCSSGGGPNGIFASPRRWLQQRKFQ 180
Query: 181 SPPDSRGHPYVVWKSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCD 240
SPPDSRGHPYVVWKSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCD
Sbjct: 181 SPPDSRGHPYVVWKSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCD 240
Query: 241 LSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDL 300
LSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDL
Sbjct: 241 LSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDL 300
Query: 301 QRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRG 360
QRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRG
Sbjct: 301 QRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRG 360
Query: 361 AMSVDSITDLDDNQSRLLEALQLSLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQH 420
AMSVDSITDLDDNQSRLLEALQLSLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQH
Sbjct: 361 AMSVDSITDLDDNQSRLLEALQLSLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQH 420
Query: 421 LEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPL 480
LEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPL
Sbjct: 421 LEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPL 480
Query: 481 LTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKD 540
LTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKD
Sbjct: 481 LTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKD 540
Query: 541 GQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEA 600
GQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEA
Sbjct: 541 GQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEA 600
Query: 601 LFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNK 660
LFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNK
Sbjct: 601 LFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNK 660
Query: 661 ASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPG 720
ASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPG
Sbjct: 661 ASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPG 720
Query: 721 PRLGK 725
PRLGK
Sbjct: 721 PRLGK 725
>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
Length = 771
Score = 1014 bits (2621), Expect = 0.0
Identities = 522/522 (100%), Positives = 522/522 (100%)
Query: 204 MSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLSCQITIPKDGQKRKKSLRKKLD 263
MSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLSCQITIPKDGQKRKKSLRKKLD
Sbjct: 1 MSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLSCQITIPKDGQKRKKSLRKKLD 60
Query: 264 SLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDLQRDEQKDASDFVASLLPFGNKRQ 323
SLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDLQRDEQKDASDFVASLLPFGNKRQ
Sbjct: 61 SLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDLQRDEQKDASDFVASLLPFGNKRQ 120
Query: 324 NKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQL 383
NKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQL
Sbjct: 121 NKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQL 180
Query: 384 SLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQ 443
SLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQ
Sbjct: 181 SLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQ 240
Query: 444 LREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGT 503
LREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGT
Sbjct: 241 LREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGT 300
Query: 504 LQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL 563
LQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL
Sbjct: 301 LQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL 360
Query: 564 HKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDV 623
HKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDV
Sbjct: 361 HKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDV 420
Query: 624 VDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNKASSGDISPYDNNSPVLSERSLLA 683
VDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNKASSGDISPYDNNSPVLSERSLLA
Sbjct: 421 VDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNKASSGDISPYDNNSPVLSERSLLA 480
Query: 684 MQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPGPRLGK 725
MQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPGPRLGK
Sbjct: 481 MQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPGPRLGK 522
>gi|40255080 hypothetical protein LOC158763 [Homo sapiens]
Length = 547
Score = 284 bits (726), Expect = 2e-76
Identities = 183/489 (37%), Positives = 272/489 (55%), Gaps = 28/489 (5%)
Query: 210 RLRSVPIQSLSELERARLQEVAFYQLQQDCDLS---CQITIPKDGQKRKKSLRKKLDSLG 266
R + V I SLSELER +LQE A+++L LS +P D R +L K L
Sbjct: 46 RTKMVSIHSLSELERLKLQETAYHELVARHFLSEFKPDRALPID---RPNTLDKWFLIL- 101
Query: 267 KEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDLQRDEQKDASDFVASLLPFGNKRQNKE 326
+ + + + FG+ L +V+ N+ + +L Q + + A+ G +R N
Sbjct: 102 --RGQQRAVSHKTFGISLEEVLVNEFTRRKHLELTATMQVEEATGQAA----GRRRGNVV 155
Query: 327 LSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQLSLP 386
S NE P P R RRGA+SVDS+ +L+D + LL+ LQLS
Sbjct: 156 RRVFGRIRRFFSRRRNE---PTLPREFTRRGRRGAVSVDSLAELEDG-ALLLQTLQLSKI 211
Query: 387 AEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLRE 446
+ ++ +K+SLNPI +Q+P++V++CCQ +EKHGL VGIF + S +RVRQLRE
Sbjct: 212 SFPIGQRLLGSKRKMSLNPIAKQIPQVVEACCQFIEKHGLSAVGIFTLEYSVQRVRQLRE 271
Query: 447 EFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQL 506
EFD+G+DV L++ +VHDVAALLKEF RDM D LL +LY +F+ T L+P++QL LQL
Sbjct: 272 EFDQGLDVVLDDNQNVHDVAALLKEFFRDMKDSLLPDDLYMSFLLTATLKPQDQLSALQL 331
Query: 507 LIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQ 566
L+YL+PPC+ DTL RLL+ L + + +D+I DGQ V GN+MTS NLA +FG LL K
Sbjct: 332 LVYLMPPCHSDTLERLLKALHKITENCEDSIGIDGQLVPGNRMTSTNLALVFGSALLKKG 391
Query: 567 KSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDY 626
K +E S ++ + A + VV+ MI+N++ LF VPP +Q +V + ++ P+ +D+
Sbjct: 392 KFGKRE-SRKTKLGIDHYVASVNVVRAMIDNWDVLFQVPPHIQRQVAKRVWKSSPEALDF 450
Query: 627 LLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNKASSGDISPYDNNSPVLSERSLLAMQE 686
+ RR + S + E + +S ++ A P D S +E
Sbjct: 451 IRRRNLRKIQSARIKMEEDALLSDPVETSAEARAAVLAQSKPSDEGS----------SEE 500
Query: 687 DAAPGGSEK 695
A P G+ +
Sbjct: 501 PAVPSGTAR 509
>gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]
Length = 439
Score = 97.8 bits (242), Expect = 3e-20
Identities = 52/160 (32%), Positives = 90/160 (56%), Gaps = 11/160 (6%)
Query: 404 NPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVH 463
NP +P ++ +L+ H L T GIFR ++ + VR+++++++ G+ V ++ + +H
Sbjct: 253 NPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELH 312
Query: 464 DVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLL 523
A +LK FLR++P+PLLT +LY + L ++ +++ ++ LP N L L
Sbjct: 313 LPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLT 372
Query: 524 QFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL 563
FL ++ H+D NKMT+ NLA +FGPNLL
Sbjct: 373 AFLVQISAHSDQ-----------NKMTNTNLAVVFGPNLL 401
>gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b
[Homo sapiens]
Length = 1075
Score = 97.1 bits (240), Expect = 6e-20
Identities = 63/206 (30%), Positives = 108/206 (52%), Gaps = 23/206 (11%)
Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGID--VSLEEEHSVHDVAA 467
+P +V+SC +++ +GLQ GIFRV S+ V ++ F+RG D V + E ++ VA
Sbjct: 495 IPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAG 554
Query: 468 LLKEFLRDMPDPLLTRELYTAFINTLLLE-PEEQLGTLQLLIYLLPPCNCDTLHRLLQFL 526
+LK + R + +PL +E + I+T+ LE P E++ +Q ++ LP + L FL
Sbjct: 555 VLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFL 614
Query: 527 SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTA 586
+ +++++D+N+ M NLA FGP L+H D V A E
Sbjct: 615 NHLSQYSDENM-----------MDPYNLAICFGPTLMHIPDGQD---PVSCQAHINE--- 657
Query: 587 IIAVVQKMIENYEALFMVPPDLQNEV 612
V++ +I ++EA+F P +L+ V
Sbjct: 658 ---VIKTIIIHHEAIFPSPRELEGPV 680
>gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a
[Homo sapiens]
Length = 1099
Score = 97.1 bits (240), Expect = 6e-20
Identities = 63/206 (30%), Positives = 108/206 (52%), Gaps = 23/206 (11%)
Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGID--VSLEEEHSVHDVAA 467
+P +V+SC +++ +GLQ GIFRV S+ V ++ F+RG D V + E ++ VA
Sbjct: 519 IPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAG 578
Query: 468 LLKEFLRDMPDPLLTRELYTAFINTLLLE-PEEQLGTLQLLIYLLPPCNCDTLHRLLQFL 526
+LK + R + +PL +E + I+T+ LE P E++ +Q ++ LP + L FL
Sbjct: 579 VLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFL 638
Query: 527 SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTA 586
+ +++++D+N+ M NLA FGP L+H D V A E
Sbjct: 639 NHLSQYSDENM-----------MDPYNLAICFGPTLMHIPDGQD---PVSCQAHINE--- 681
Query: 587 IIAVVQKMIENYEALFMVPPDLQNEV 612
V++ +I ++EA+F P +L+ V
Sbjct: 682 ---VIKTIIIHHEAIFPSPRELEGPV 704
>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
Length = 459
Score = 96.3 bits (238), Expect = 1e-19
Identities = 58/196 (29%), Positives = 98/196 (50%), Gaps = 22/196 (11%)
Query: 411 PRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRG---IDVSLEEEHSVHDVAA 467
P +VD C + +E GL + G++RV + ++ FDR D+S+ ++ +
Sbjct: 282 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 341
Query: 468 LLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFL 526
LK + RD+P PL+T + Y FI + +++P+EQL TL + LLPP +C+TL L+ L
Sbjct: 342 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 401
Query: 527 SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTA 586
V H +N+ M + NL +FGP L+ + + + A +
Sbjct: 402 KRVTLHEKENL-----------MNAENLGIVFGPTLMRSPE-------LDAMAALNDIRY 443
Query: 587 IIAVVQKMIENYEALF 602
VV+ +I+N + LF
Sbjct: 444 QRLVVELLIKNEDILF 459
>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
Length = 433
Score = 96.3 bits (238), Expect = 1e-19
Identities = 58/196 (29%), Positives = 98/196 (50%), Gaps = 22/196 (11%)
Query: 411 PRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRG---IDVSLEEEHSVHDVAA 467
P +VD C + +E GL + G++RV + ++ FDR D+S+ ++ +
Sbjct: 256 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 315
Query: 468 LLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFL 526
LK + RD+P PL+T + Y FI + +++P+EQL TL + LLPP +C+TL L+ L
Sbjct: 316 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 375
Query: 527 SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTA 586
V H +N+ M + NL +FGP L+ + + + A +
Sbjct: 376 KRVTLHEKENL-----------MNAENLGIVFGPTLMRSPE-------LDAMAALNDIRY 417
Query: 587 IIAVVQKMIENYEALF 602
VV+ +I+N + LF
Sbjct: 418 QRLVVELLIKNEDILF 433
>gi|56119110 family with sequence similarity 13, member A1 isoform a
[Homo sapiens]
Length = 1023
Score = 95.1 bits (235), Expect = 2e-19
Identities = 71/211 (33%), Positives = 104/211 (49%), Gaps = 27/211 (12%)
Query: 401 LSLNPIYRQ------VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDV 454
+SL + RQ +P +V + ++L +HGL G+FRV + K V QLR +F+ G+ V
Sbjct: 43 VSLQELERQGLTENGIPAVVWNIVEYLTQHGLTQEGLFRVNGNVKVVEQLRLKFESGVPV 102
Query: 455 SLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTLL-LEPEEQLGTLQLLIYLLPP 513
L ++ V A+LLK FLR++PD L+T L FI + Q +L+ LI LP
Sbjct: 103 ELGKDGDVCSAASLLKLFLRELPDSLITSALQPRFIQLFQDGRNDVQESSLRDLIKELPD 162
Query: 514 CNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEF 573
+ L L QFL+ VA+H N+M NLAT+FGPN H +
Sbjct: 163 THYCLLKYLCQFLTKVAKHH-----------VQNRMNVHNLATVFGPNCFHVPPGLE--- 208
Query: 574 SVQSSARAEESTAIIAVVQKMIENYEALFMV 604
+E ++ K++ENY LF V
Sbjct: 209 ------GMKEQDLCNKIMAKILENYNTLFEV 233
>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
sapiens]
Length = 653
Score = 94.0 bits (232), Expect = 5e-19
Identities = 65/209 (31%), Positives = 106/209 (50%), Gaps = 25/209 (11%)
Query: 408 RQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAA 467
R P LV+ C + + GL+ G+FR+ V++L++ FD G S + VH VA+
Sbjct: 55 RLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVAS 114
Query: 468 LLKEFLRDMPDPLLTRELYTAFIN-TLLLEPEEQLGTLQLL--IYLLPPCNCDTLHRLLQ 524
LLK +LR++P+P++ Y F++ LL EE+ G +L + LP N + L + +
Sbjct: 115 LLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICR 174
Query: 525 FLSIVARHADDNISKDGQEVTG-NKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEE 583
FL V Q +G NKM+ NLAT+FGPN+L + V+ E
Sbjct: 175 FLDEV------------QSYSGVNKMSVQNLATVFGPNILRPK--------VEDPLTIME 214
Query: 584 STAII-AVVQKMIENYEALFMVPPDLQNE 611
T ++ ++ MI ++ LF +LQ++
Sbjct: 215 GTVVVQQLMSVMISKHDCLFPKDAELQSK 243
>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
sapiens]
Length = 655
Score = 94.0 bits (232), Expect = 5e-19
Identities = 65/209 (31%), Positives = 106/209 (50%), Gaps = 25/209 (11%)
Query: 408 RQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAA 467
R P LV+ C + + GL+ G+FR+ V++L++ FD G S + VH VA+
Sbjct: 57 RLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVAS 116
Query: 468 LLKEFLRDMPDPLLTRELYTAFIN-TLLLEPEEQLGTLQLL--IYLLPPCNCDTLHRLLQ 524
LLK +LR++P+P++ Y F++ LL EE+ G +L + LP N + L + +
Sbjct: 117 LLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICR 176
Query: 525 FLSIVARHADDNISKDGQEVTG-NKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEE 583
FL V Q +G NKM+ NLAT+FGPN+L + V+ E
Sbjct: 177 FLDEV------------QSYSGVNKMSVQNLATVFGPNILRPK--------VEDPLTIME 216
Query: 584 STAII-AVVQKMIENYEALFMVPPDLQNE 611
T ++ ++ MI ++ LF +LQ++
Sbjct: 217 GTVVVQQLMSVMISKHDCLFPKDAELQSK 245
>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
Length = 748
Score = 94.0 bits (232), Expect = 5e-19
Identities = 65/209 (31%), Positives = 106/209 (50%), Gaps = 25/209 (11%)
Query: 408 RQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAA 467
R P LV+ C + + GL+ G+FR+ V++L++ FD G S + VH VA+
Sbjct: 150 RLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVAS 209
Query: 468 LLKEFLRDMPDPLLTRELYTAFIN-TLLLEPEEQLGTLQLL--IYLLPPCNCDTLHRLLQ 524
LLK +LR++P+P++ Y F++ LL EE+ G +L + LP N + L + +
Sbjct: 210 LLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICR 269
Query: 525 FLSIVARHADDNISKDGQEVTG-NKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEE 583
FL V Q +G NKM+ NLAT+FGPN+L + V+ E
Sbjct: 270 FLDEV------------QSYSGVNKMSVQNLATVFGPNILRPK--------VEDPLTIME 309
Query: 584 STAII-AVVQKMIENYEALFMVPPDLQNE 611
T ++ ++ MI ++ LF +LQ++
Sbjct: 310 GTVVVQQLMSVMISKHDCLFPKDAELQSK 338
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 92.8 bits (229), Expect = 1e-18
Identities = 55/166 (33%), Positives = 92/166 (55%), Gaps = 15/166 (9%)
Query: 408 RQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRG---IDVSLEEEHSVHD 464
R +P +VD CC+ +E+ GL+ GI+RV + + ++EE ++G ID+ ++ ++
Sbjct: 1159 RYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLNV 1218
Query: 465 VAALLKEFLRDMPDPLLTRELYTAFINTLLLE-PEEQLGTLQLLIYLLPPCNCDTLHRLL 523
+++LLK F R +P+PL T + Y FI E P ++L TL+ LI+ LP + +TL L
Sbjct: 1219 ISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETLKFLS 1278
Query: 524 QFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSS 569
L VA +++ NKM NLA +FGP L+ + +
Sbjct: 1279 AHLKTVAENSEK-----------NKMEPRNLAIVFGPTLVRTSEDN 1313
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 92.4 bits (228), Expect = 1e-18
Identities = 57/194 (29%), Positives = 106/194 (54%), Gaps = 14/194 (7%)
Query: 408 RQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAA 467
R VP +V+ ++E HGL T GI+R S ++++LR+ D + +++++H +A+
Sbjct: 2073 RTVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAESVNLDDYNIHVIAS 2132
Query: 468 LLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFL 526
+ K++LRD+P+PL+T ELY F+ + L E +E + + +I L + +TL RL+ L
Sbjct: 2133 VFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQLSRTHLNTLERLIFHL 2192
Query: 527 SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTA 586
+A D N+M++ LA +F P +L ++D SVQ ++ +T
Sbjct: 2193 VRIALQEDT-----------NRMSANALAIVFAPCILRCPDTTDPLQSVQDISKT--TTC 2239
Query: 587 IIAVVQKMIENYEA 600
+ +V + + Y+A
Sbjct: 2240 VELIVVEQMNKYKA 2253
>gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]
Length = 1528
Score = 91.7 bits (226), Expect = 2e-18
Identities = 65/211 (30%), Positives = 100/211 (47%), Gaps = 23/211 (10%)
Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469
+P+ + ++L H L VG+FR K R++ LR+ + ID E S +DVA +L
Sbjct: 1091 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 1150
Query: 470 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528
K++ RD+P+PL+T +L F+ P++Q L ++ I LLP N + L LL FLS
Sbjct: 1151 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 1210
Query: 529 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH-----KQKSSDKEFSVQSS----- 578
V V N+MT NLA P+L H ++ SS + + S
Sbjct: 1211 VT-----------AAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPD 1259
Query: 579 -ARAEESTAIIAVVQKMIENYEALFMVPPDL 608
E+ A + MI + LF VP ++
Sbjct: 1260 QKDLNENLAATQGLAHMIAECKKLFQVPEEM 1290
>gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]
Length = 1091
Score = 91.7 bits (226), Expect = 2e-18
Identities = 65/211 (30%), Positives = 100/211 (47%), Gaps = 23/211 (10%)
Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469
+P+ + ++L H L VG+FR K R++ LR+ + ID E S +DVA +L
Sbjct: 654 LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADML 713
Query: 470 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528
K++ RD+P+PL+T +L F+ P++Q L ++ I LLP N + L LL FLS
Sbjct: 714 KQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSD 773
Query: 529 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH-----KQKSSDKEFSVQSS----- 578
V V N+MT NLA P+L H ++ SS + + S
Sbjct: 774 VT-----------AAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPD 822
Query: 579 -ARAEESTAIIAVVQKMIENYEALFMVPPDL 608
E+ A + MI + LF VP ++
Sbjct: 823 QKDLNENLAATQGLAHMIAECKKLFQVPEEM 853
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 91.3 bits (225), Expect = 3e-18
Identities = 75/241 (31%), Positives = 123/241 (51%), Gaps = 22/241 (9%)
Query: 403 LNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHS- 461
L + R++ +++C L G++ G+FR+ + +++L++ SLEE S
Sbjct: 282 LQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPH-SLEEFCSD 340
Query: 462 VHDVAALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLH 520
H VA LK +LR++P+PL+T +LY ++ L EP +L LQ + LPP N L
Sbjct: 341 PHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLR 400
Query: 521 RLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL-HKQKSSDKEFSVQSSA 579
L++FL+ +A + QEV NKMT N+A + GPNLL +K D+ Q A
Sbjct: 401 YLMKFLARLA---------EEQEV--NKMTPSNIAIVLGPNLLWPPEKEGDQ---AQLDA 446
Query: 580 RAEESTAIIAVVQKMIENYEALFMVPPDLQNEV--LISLLETDPDVVDYLLRRKASQSSS 637
+ S ++ VV+ +I++ + LF P D+ V L S + V D L + ++
Sbjct: 447 ASVSSIQVVGVVEALIQSADTLF--PGDINFNVSGLFSAVTLQDTVSDRLASEELPSTAV 504
Query: 638 P 638
P
Sbjct: 505 P 505
>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
Length = 698
Score = 90.5 bits (223), Expect = 5e-18
Identities = 63/202 (31%), Positives = 100/202 (49%), Gaps = 23/202 (11%)
Query: 408 RQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAA 467
R P LV+ C + + GL G+FR+ VR L++ FD G + VH VA+
Sbjct: 170 RLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVAS 229
Query: 468 LLKEFLRDMPDPLLTRELYTAFIN-TLLLEPEEQLGTLQLL--IYLLPPCNCDTLHRLLQ 524
LLK +LR++P+P++ Y F++ LL +E GTL+L + LP N + L + +
Sbjct: 230 LLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICK 289
Query: 525 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 584
FL V +++ NKM+ NLAT+FGPN+L Q V+ E
Sbjct: 290 FLDEVQAYSN-----------VNKMSVQNLATVFGPNILRPQ--------VEDPVTIMEG 330
Query: 585 TAIIA-VVQKMIENYEALFMVP 605
T+++ ++ +I + LF P
Sbjct: 331 TSLVQHLMTVLIRKHSQLFTAP 352
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 90.1 bits (222), Expect = 7e-18
Identities = 50/162 (30%), Positives = 86/162 (53%), Gaps = 13/162 (8%)
Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLR--EEFDRGIDVSLEEEHSVHDVAA 467
VP+ V C +H+E+HGL GI+RV + +++LR D +D++ + +H +
Sbjct: 669 VPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITG 728
Query: 468 LLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLS 527
LK F R++P+PL T + F+N + EP +++ ++ LI LP N DT+ L + L
Sbjct: 729 ALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLR 788
Query: 528 IVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSS 569
V + + N+MT ++A +FGP LL +K +
Sbjct: 789 RVIENGEK-----------NRMTYQSIAIVFGPTLLKPEKET 819
>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
Length = 1397
Score = 89.7 bits (221), Expect = 9e-18
Identities = 56/166 (33%), Positives = 94/166 (56%), Gaps = 15/166 (9%)
Query: 408 RQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGI-DVSLEEE--HSVHD 464
++VP +V +CC+ +E GL++ GI+RV + V L+E+ +RG D++L++E ++
Sbjct: 823 QRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLNV 882
Query: 465 VAALLKEFLRDMPDPLLTRELYTAFINTLLLE-PEEQLGTLQLLIYLLPPCNCDTLHRLL 523
+++LLK F R +P+PL T + Y FI +E E++ TL+ LI LP +TL L+
Sbjct: 883 ISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHYYETLKFLV 942
Query: 524 QFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSS 569
L +A H++ NKM NLA +FGP L+ + +
Sbjct: 943 GHLKTIADHSEK-----------NKMEPRNLALVFGPTLVRTSEDN 977
>gi|215820652 StAR-related lipid transfer (START) domain containing
8 isoform b [Homo sapiens]
Length = 1023
Score = 89.7 bits (221), Expect = 9e-18
Identities = 63/211 (29%), Positives = 98/211 (46%), Gaps = 24/211 (11%)
Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469
+P+ + ++L L VGIFR K R++ LR+ + D E S +DVA LL
Sbjct: 585 LPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLL 644
Query: 470 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528
K++ RD+P+P+ T +L T F+ L P++Q L Q LLP N + L LL FLS
Sbjct: 645 KQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSD 704
Query: 529 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSAR-------- 580
+A + N+MT+ NLA P++ H S S + ++
Sbjct: 705 IASAEE------------NQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPG 752
Query: 581 ---AEESTAIIAVVQKMIENYEALFMVPPDL 608
++ A + MI + + LF VP D+
Sbjct: 753 PRDLSDNMAATQGLSHMISDCKKLFQVPQDM 783
>gi|215820650 StAR-related lipid transfer (START) domain containing
8 isoform a [Homo sapiens]
Length = 1103
Score = 89.7 bits (221), Expect = 9e-18
Identities = 63/211 (29%), Positives = 98/211 (46%), Gaps = 24/211 (11%)
Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469
+P+ + ++L L VGIFR K R++ LR+ + D E S +DVA LL
Sbjct: 665 LPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLL 724
Query: 470 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528
K++ RD+P+P+ T +L T F+ L P++Q L Q LLP N + L LL FLS
Sbjct: 725 KQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSD 784
Query: 529 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSAR-------- 580
+A + N+MT+ NLA P++ H S S + ++
Sbjct: 785 IASAEE------------NQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPG 832
Query: 581 ---AEESTAIIAVVQKMIENYEALFMVPPDL 608
++ A + MI + + LF VP D+
Sbjct: 833 PRDLSDNMAATQGLSHMISDCKKLFQVPQDM 863
>gi|31543659 StAR-related lipid transfer (START) domain containing 8
isoform b [Homo sapiens]
Length = 1023
Score = 89.7 bits (221), Expect = 9e-18
Identities = 63/211 (29%), Positives = 98/211 (46%), Gaps = 24/211 (11%)
Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469
+P+ + ++L L VGIFR K R++ LR+ + D E S +DVA LL
Sbjct: 585 LPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLL 644
Query: 470 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528
K++ RD+P+P+ T +L T F+ L P++Q L Q LLP N + L LL FLS
Sbjct: 645 KQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSD 704
Query: 529 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSAR-------- 580
+A + N+MT+ NLA P++ H S S + ++
Sbjct: 705 IASAEE------------NQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPG 752
Query: 581 ---AEESTAIIAVVQKMIENYEALFMVPPDL 608
++ A + MI + + LF VP D+
Sbjct: 753 PRDLSDNMAATQGLSHMISDCKKLFQVPQDM 783
>gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Homo
sapiens]
Length = 622
Score = 86.7 bits (213), Expect = 8e-17
Identities = 81/260 (31%), Positives = 113/260 (43%), Gaps = 36/260 (13%)
Query: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVH--DVA 466
QVP ++ + LEK GL GI RV S+ RV+ L ++ +R L VH D +
Sbjct: 287 QVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDAS 346
Query: 467 ALLKEFLRDMPDPLLTRELYTAF-INTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525
LLK F+R +P PLLT E AF + + +++L L LLI +LP N + L LL+F
Sbjct: 347 DLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEF 406
Query: 526 L-SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 584
L +VAR NKMT N++T+ PNL Q K + AE +
Sbjct: 407 LRKVVAREQH------------NKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGA 454
Query: 585 TAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSE 644
VVQ M+ + L+ V L +V RK + SSS +
Sbjct: 455 A---EVVQIMVHYQDLLWTVASFLVAQV-----------------RKLNDSSSRRPQLCD 494
Query: 645 VSFSVGGRHSSTDSNKASSG 664
R D +KA G
Sbjct: 495 AGLKTWLRRMHADRDKAGDG 514
>gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo
sapiens]
Length = 622
Score = 86.7 bits (213), Expect = 8e-17
Identities = 81/260 (31%), Positives = 113/260 (43%), Gaps = 36/260 (13%)
Query: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVH--DVA 466
QVP ++ + LEK GL GI RV S+ RV+ L ++ +R L VH D +
Sbjct: 287 QVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDAS 346
Query: 467 ALLKEFLRDMPDPLLTRELYTAF-INTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525
LLK F+R +P PLLT E AF + + +++L L LLI +LP N + L LL+F
Sbjct: 347 DLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEF 406
Query: 526 L-SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 584
L +VAR NKMT N++T+ PNL Q K + AE +
Sbjct: 407 LRKVVAREQH------------NKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGA 454
Query: 585 TAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSE 644
VVQ M+ + L+ V L +V RK + SSS +
Sbjct: 455 A---EVVQIMVHYQDLLWTVASFLVAQV-----------------RKLNDSSSRRPQLCD 494
Query: 645 VSFSVGGRHSSTDSNKASSG 664
R D +KA G
Sbjct: 495 AGLKTWLRRMHADRDKAGDG 514
>gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [Homo
sapiens]
Length = 622
Score = 86.7 bits (213), Expect = 8e-17
Identities = 81/260 (31%), Positives = 113/260 (43%), Gaps = 36/260 (13%)
Query: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVH--DVA 466
QVP ++ + LEK GL GI RV S+ RV+ L ++ +R L VH D +
Sbjct: 287 QVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDAS 346
Query: 467 ALLKEFLRDMPDPLLTRELYTAF-INTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525
LLK F+R +P PLLT E AF + + +++L L LLI +LP N + L LL+F
Sbjct: 347 DLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEF 406
Query: 526 L-SIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 584
L +VAR NKMT N++T+ PNL Q K + AE +
Sbjct: 407 LRKVVAREQH------------NKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGA 454
Query: 585 TAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSE 644
VVQ M+ + L+ V L +V RK + SSS +
Sbjct: 455 A---EVVQIMVHYQDLLWTVASFLVAQV-----------------RKLNDSSSRRPQLCD 494
Query: 645 VSFSVGGRHSSTDSNKASSG 664
R D +KA G
Sbjct: 495 AGLKTWLRRMHADRDKAGDG 514
>gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]
Length = 663
Score = 86.7 bits (213), Expect = 8e-17
Identities = 67/211 (31%), Positives = 104/211 (49%), Gaps = 25/211 (11%)
Query: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSV--HDVA 466
++P + +E+ GL+T G+ R+ + R++ L +E + SV HD A
Sbjct: 341 RIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAA 400
Query: 467 ALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525
+LLK F+R++P PLL+ E AF L ++QL L LL+ LLP N DTL LL+F
Sbjct: 401 SLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEF 460
Query: 526 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQ----KSSDKEFSVQSSARA 581
L V DN K NKMT +N+A + PNL KSS++ V ++ A
Sbjct: 461 LQRVI----DNKEK-------NKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTA 509
Query: 582 EESTAIIAVVQKMIENYEALFMVPPDLQNEV 612
+ +I+ + L+ +P + N+V
Sbjct: 510 N-------TMHLLIKYQKLLWTIPKFIVNQV 533
>gi|41281907 StAR-related lipid transfer (START) domain containing
13 isoform beta [Homo sapiens]
Length = 1105
Score = 84.3 bits (207), Expect = 4e-16
Identities = 65/225 (28%), Positives = 111/225 (49%), Gaps = 28/225 (12%)
Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRV---RQLREEFDRGIDVSLEEEHSVHDVA 466
+P+ + ++L + L VG+FR K R+ RQ+ E F ++ E+ S +DVA
Sbjct: 668 LPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPENVNY---EDQSAYDVA 724
Query: 467 ALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525
++K+F RD+P+PL T +L F++ + E++L +Q I LL N + L LL F
Sbjct: 725 DMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCF 784
Query: 526 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH----KQKSS----DKEFSVQS 577
L+ V ++ N+MT +NLA P+L H K++SS K+++
Sbjct: 785 LNDVVNLVEE-----------NQMTPMNLAVCLAPSLFHLNLLKKESSPRVIQKKYATGK 833
Query: 578 SARAE--ESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETD 620
+ + E+ A + MI + LF VP +L + S +E +
Sbjct: 834 PDQKDLNENLAAAQGLAHMIMECDRLFEVPHELVAQSRNSYVEAE 878
>gi|16445031 StAR-related lipid transfer (START) domain containing
13 isoform gamma [Homo sapiens]
Length = 995
Score = 84.3 bits (207), Expect = 4e-16
Identities = 65/225 (28%), Positives = 111/225 (49%), Gaps = 28/225 (12%)
Query: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRV---RQLREEFDRGIDVSLEEEHSVHDVA 466
+P+ + ++L + L VG+FR K R+ RQ+ E F ++ E+ S +DVA
Sbjct: 558 LPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPENVNY---EDQSAYDVA 614
Query: 467 ALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525
++K+F RD+P+PL T +L F++ + E++L +Q I LL N + L LL F
Sbjct: 615 DMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCF 674
Query: 526 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH----KQKSS----DKEFSVQS 577
L+ V ++ N+MT +NLA P+L H K++SS K+++
Sbjct: 675 LNDVVNLVEE-----------NQMTPMNLAVCLAPSLFHLNLLKKESSPRVIQKKYATGK 723
Query: 578 SARAE--ESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETD 620
+ + E+ A + MI + LF VP +L + S +E +
Sbjct: 724 PDQKDLNENLAAAQGLAHMIMECDRLFEVPHELVAQSRNSYVEAE 768
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,958,253
Number of Sequences: 37866
Number of extensions: 1675335
Number of successful extensions: 9768
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 126
Number of HSP's successfully gapped in prelim test: 254
Number of HSP's that attempted gapping in prelim test: 8921
Number of HSP's gapped (non-prelim): 894
length of query: 765
length of database: 18,247,518
effective HSP length: 110
effective length of query: 655
effective length of database: 14,082,258
effective search space: 9223878990
effective search space used: 9223878990
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.