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Search of human proteins with 94538350
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|94538350 protocadherin 17 precursor [Homo sapiens]
(1159 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|94538350 protocadherin 17 precursor [Homo sapiens] 2331 0.0
gi|157426847 protocadherin 19 isoform a [Homo sapiens] 983 0.0
gi|157426845 protocadherin 19 isoform b [Homo sapiens] 977 0.0
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 780 0.0
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens] 681 0.0
gi|14589929 protocadherin 18 precursor [Homo sapiens] 659 0.0
gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso... 546 e-155
gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precurs... 544 e-154
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs... 514 e-145
gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur... 514 e-145
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur... 510 e-144
gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precur... 510 e-144
gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precurs... 509 e-144
gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precurs... 509 e-144
gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precurs... 508 e-143
gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precurs... 508 e-143
gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precur... 506 e-143
gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precur... 506 e-143
gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precurs... 504 e-142
gi|14196477 protocadherin gamma subfamily A, 7 isoform 2 precurs... 504 e-142
gi|14270508 protocadherin gamma subfamily B, 7 isoform 2 precurs... 499 e-141
gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precurs... 499 e-141
gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precurs... 495 e-139
gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precurs... 495 e-139
gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precurs... 490 e-138
gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precurs... 490 e-138
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 489 e-138
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 489 e-138
gi|11128029 protocadherin gamma subfamily B, 6 isoform 1 precurs... 487 e-137
gi|14270502 protocadherin gamma subfamily B, 6 isoform 2 precurs... 487 e-137
>gi|94538350 protocadherin 17 precursor [Homo sapiens]
Length = 1159
Score = 2331 bits (6042), Expect = 0.0
Identities = 1159/1159 (100%), Positives = 1159/1159 (100%)
Query: 1 MYLSICCCFLLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSK 60
MYLSICCCFLLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSK
Sbjct: 1 MYLSICCCFLLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSK 60
Query: 61 SGSYRVLENSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKV 120
SGSYRVLENSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKV
Sbjct: 61 SGSYRVLENSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKV 120
Query: 121 EIQDINDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFG 180
EIQDINDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFG
Sbjct: 121 EIQDINDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFG 180
Query: 181 LDVKSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNS 240
LDVKSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNS
Sbjct: 181 LDVKSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNS 240
Query: 241 PVFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKT 300
PVFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKT
Sbjct: 241 PVFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKT 300
Query: 301 GLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGA 360
GLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGA
Sbjct: 301 GLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGA 360
Query: 361 LSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDN 420
LSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDN
Sbjct: 361 LSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDN 420
Query: 421 FYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQ 480
FYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQ
Sbjct: 421 FYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQ 480
Query: 481 VHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSF 540
VHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSF
Sbjct: 481 VHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSF 540
Query: 541 NFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRN 600
NFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRN
Sbjct: 541 NFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRN 600
Query: 601 AGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVE 660
AGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVE
Sbjct: 601 AGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVE 660
Query: 661 LVVKVTDHGKPTLSAVAKLIIRSVSGSLPEGVPRVNGEQHHWDMSLPLIVTLSTISIILL 720
LVVKVTDHGKPTLSAVAKLIIRSVSGSLPEGVPRVNGEQHHWDMSLPLIVTLSTISIILL
Sbjct: 661 LVVKVTDHGKPTLSAVAKLIIRSVSGSLPEGVPRVNGEQHHWDMSLPLIVTLSTISIILL 720
Query: 721 AAMITIAVKCKRENKEIRTYNCRIAEYSHPQLGGGKGKKKKINKNDIMLVQSEVEERNAM 780
AAMITIAVKCKRENKEIRTYNCRIAEYSHPQLGGGKGKKKKINKNDIMLVQSEVEERNAM
Sbjct: 721 AAMITIAVKCKRENKEIRTYNCRIAEYSHPQLGGGKGKKKKINKNDIMLVQSEVEERNAM 780
Query: 781 NVMNVVSSPSLATSPMYFDYQTRLPLSSPRSEVMYLKPASNNLTVPQGHAGCHTSFTGQG 840
NVMNVVSSPSLATSPMYFDYQTRLPLSSPRSEVMYLKPASNNLTVPQGHAGCHTSFTGQG
Sbjct: 781 NVMNVVSSPSLATSPMYFDYQTRLPLSSPRSEVMYLKPASNNLTVPQGHAGCHTSFTGQG 840
Query: 841 TNASETPATRMSIIQTDNFPAEPNYMGSRQQFVQSSSTFKDPERASLRDSGHGDSDQADS 900
TNASETPATRMSIIQTDNFPAEPNYMGSRQQFVQSSSTFKDPERASLRDSGHGDSDQADS
Sbjct: 841 TNASETPATRMSIIQTDNFPAEPNYMGSRQQFVQSSSTFKDPERASLRDSGHGDSDQADS 900
Query: 901 DQDTNKGSCCDMSVREALKMKTTSTKSQPLEQEPEECVNCTDECRVLGHSDRCWMPQFPA 960
DQDTNKGSCCDMSVREALKMKTTSTKSQPLEQEPEECVNCTDECRVLGHSDRCWMPQFPA
Sbjct: 901 DQDTNKGSCCDMSVREALKMKTTSTKSQPLEQEPEECVNCTDECRVLGHSDRCWMPQFPA 960
Query: 961 ANQAENADYRTNLFVPTVEANVETETYETVNPTGKKTFCTFGKDKREHTILIANVKPYLK 1020
ANQAENADYRTNLFVPTVEANVETETYETVNPTGKKTFCTFGKDKREHTILIANVKPYLK
Sbjct: 961 ANQAENADYRTNLFVPTVEANVETETYETVNPTGKKTFCTFGKDKREHTILIANVKPYLK 1020
Query: 1021 AKRALSPLLQEVPSASSSPTKACIEPCTSTKGSLDGCEAKPGALAEASSQYLPTDSQYLS 1080
AKRALSPLLQEVPSASSSPTKACIEPCTSTKGSLDGCEAKPGALAEASSQYLPTDSQYLS
Sbjct: 1021 AKRALSPLLQEVPSASSSPTKACIEPCTSTKGSLDGCEAKPGALAEASSQYLPTDSQYLS 1080
Query: 1081 PSKQPRDPPFMASDQMARVFADVHSRASRDSSEMGAVLEQLDHPNRDLGRESVDAEEVVR 1140
PSKQPRDPPFMASDQMARVFADVHSRASRDSSEMGAVLEQLDHPNRDLGRESVDAEEVVR
Sbjct: 1081 PSKQPRDPPFMASDQMARVFADVHSRASRDSSEMGAVLEQLDHPNRDLGRESVDAEEVVR 1140
Query: 1141 EIDKLLQDCRGNDPVAVRK 1159
EIDKLLQDCRGNDPVAVRK
Sbjct: 1141 EIDKLLQDCRGNDPVAVRK 1159
>gi|157426847 protocadherin 19 isoform a [Homo sapiens]
Length = 1101
Score = 983 bits (2542), Expect = 0.0
Identities = 542/1062 (51%), Positives = 707/1062 (66%), Gaps = 53/1062 (4%)
Query: 10 LLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLEN 69
+LW A L NL YSV EEQ AGTVI N+ +DAR + G R ++ ++RV+ N
Sbjct: 14 ILWTQAAALINLKYSVEEEQRAGTVIANVAKDAR-EAGFALDPR------QASAFRVVSN 66
Query: 70 SAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKVEIQDINDNA 129
SAPHL+D++ SGLL TKQ+IDR+ LCR + KC +SLEV ++ EIC+IKVEI+D+NDNA
Sbjct: 67 SAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNA 126
Query: 130 PSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDG 189
PSF + QIE++ISE A+PGTR PL SA+DPD+G G++TY LT ++ LFGL++K+RGDG
Sbjct: 127 PSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNE--LFGLEIKTRGDG 184
Query: 190 TKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYL 249
++F ELV++K+LDRE Q+H++ +TALDGG+PPR TV +++KV DSNDN+PVF +Y
Sbjct: 185 SRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYA 244
Query: 250 VELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNL 309
V +PEN+P T VI LNA+D DEG NG+V+YSF YV DR RELF IDP +GL+ V G L
Sbjct: 245 VSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGAL 304
Query: 310 DYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQG--ALSEAAPP 367
DYEE + E+DVQA+DLGPN IPAHCKVTV ++D NDN P I +SV +SE+APP
Sbjct: 305 DYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPP 364
Query: 368 GTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTD 427
G VIALVRV+DRDSG NG++QCR+L G+VPF+L+E Y++F T++ D
Sbjct: 365 GYVIALVRVSDRDSGLNGRVQCRLL---------------GNVPFRLQE-YESFSTILVD 408
Query: 428 RPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIP 487
LDRE D+YN+TI ARDGG P L S KSF + I DENDN P F+K Y + V ENN P
Sbjct: 409 GRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTP 468
Query: 488 GEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKA 547
G YL SV A+DPDLG NG+VSY I+PS + D+ ++TYVS+NP +G IYALRSFN EQTKA
Sbjct: 469 GAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKA 528
Query: 548 FEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRNAGLGYLV 607
FEFKVLAKD G P+ L+SNATVRV +LDVNDN PVI P L N TAE+ +PRN+G+GYLV
Sbjct: 529 FEFKVLAKDGGLPS-LQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLV 587
Query: 608 STVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTD 667
+ V+A D D GE+GR+TY++ +G D FEID +GE+RT F E EL+V D
Sbjct: 588 TVVKAEDYDEGENGRVTYDMTEG-DRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHD 646
Query: 668 HGKPTLSAVA-KLIIRSVSGSLPEGVPRVNGEQHHWDMSLPLIVTLSTISIILLAAMITI 726
HGK +LSA A LI S + E + VN +SL I+ L +I+ IL MI +
Sbjct: 647 HGKTSLSASALVLIYLSPALDAQESMGSVN-------LSLIFIIALGSIAGILFVTMIFV 699
Query: 727 AVKCKRENKEIRTYNCRIAEYSHPQLGGGKGKKKKINKNDIMLVQSEVEERNAMNVMNVV 786
A+KCKR+NKEIRTYNCRIAEYS+ KKKKI+KNDI LV +VEE + MNVV
Sbjct: 700 AIKCKRDNKEIRTYNCRIAEYSYGH-QKKSSKKKKISKNDIRLVPRDVEETDK---MNVV 755
Query: 787 SSPSLATSPMYFDY-QTRLPLSSPRSEVMYLKPASNNLTVPQGHAGCHTSFTGQGTNASE 845
S SL +S YFDY Q LPL RSE +L + N + H SF QG +
Sbjct: 756 SCSSLTSSLNYFDYHQQTLPLGCRRSESTFLNVENQNTRNTSANHIYHHSFNSQGPQQPD 815
Query: 846 TPATRMSIIQTDNFPAEPNYMGSRQQFVQSSSTFKDPERASLRDSGHGDSDQADSDQDTN 905
+ + +T+N+ + NY+ SR ++SSSTFKD E SL+DSGH +SDQ DS+ D
Sbjct: 816 LIINGVPLPETENYSFDSNYVNSRAHLIKSSSTFKDLEGNSLKDSGHEESDQTDSEHDVQ 875
Query: 906 KGSCCDMSVREALKMKTTSTKSQPLEQEPEECVNCTDECRVLGHSDRCWMPQFPAANQAE 965
+ CD +V + L TS SQ + + E +C +ECR+LGHSDRCWMP+ P +++
Sbjct: 876 RSLYCDTAVNDVLNTSVTSMGSQMPDHDQNEGFHCREECRILGHSDRCWMPRNPMPIRSK 935
Query: 966 NADYRTNLFVPTVEAN-VETETYETVNPTGKKTFCTFGKDKREHTILIANVKPYLKAKRA 1024
+ ++ N+ ++EA + E Y+ PT K+TF TFGKD +H A +P LK KR
Sbjct: 936 SPEHVRNIIALSIEATAADVEAYDDCGPT-KRTFATFGKDVSDHP---AEERPTLKGKRT 991
Query: 1025 L-----SPLLQEVPSASSSPTKACIEPCTSTKGSLDGCEAKP 1061
+ SP + V + + +A I P TS KP
Sbjct: 992 VDVTICSPKVNSVIREAGNGCEA-ISPVTSPLHLKSSLPTKP 1032
>gi|157426845 protocadherin 19 isoform b [Homo sapiens]
Length = 1100
Score = 977 bits (2526), Expect = 0.0
Identities = 541/1062 (50%), Positives = 706/1062 (66%), Gaps = 54/1062 (5%)
Query: 10 LLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLEN 69
+LW A L NL YSV EEQ AGTVI N+ +DAR + G R ++ ++RV+ N
Sbjct: 14 ILWTQAAALINLKYSVEEEQRAGTVIANVAKDAR-EAGFALDPR------QASAFRVVSN 66
Query: 70 SAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKVEIQDINDNA 129
SAPHL+D++ SGLL TKQ+IDR+ LCR + KC +SLEV ++ EIC+IKVEI+D+NDNA
Sbjct: 67 SAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNA 126
Query: 130 PSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDG 189
PSF + QIE++ISE A+PGTR PL SA+DPD+G G++TY LT ++ LFGL++K+RGDG
Sbjct: 127 PSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNE--LFGLEIKTRGDG 184
Query: 190 TKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYL 249
++F ELV++K+LDRE Q+H++ +TALDGG+PPR TV +++KV DSNDN+PVF +Y
Sbjct: 185 SRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYA 244
Query: 250 VELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNL 309
V +PEN+P T VI LNA+D DEG NG+V+YSF YV DR RELF IDP +GL+ V G L
Sbjct: 245 VSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGAL 304
Query: 310 DYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQG--ALSEAAPP 367
DYEE + E+DVQA+DLGPN IPAHCKVTV ++D NDN P I +SV +SE+APP
Sbjct: 305 DYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPP 364
Query: 368 GTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTD 427
G VIALVRV+DRDSG NG++QCR+L G+VPF+L+E Y++F T++ D
Sbjct: 365 GYVIALVRVSDRDSGLNGRVQCRLL---------------GNVPFRLQE-YESFSTILVD 408
Query: 428 RPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIP 487
LDRE D+YN+TI ARDGG P L S KSF + I DENDN P F+K Y + V ENN P
Sbjct: 409 GRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTP 468
Query: 488 GEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKA 547
G YL SV A+DPDLG NG+VSY I+PS + D+ ++TYVS+NP +G IYALRSFN EQTKA
Sbjct: 469 GAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKA 528
Query: 548 FEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRNAGLGYLV 607
FEFKVLAKD G P+ L+SNATVRV +LDVNDN PVI P L N TAE+ +PRN+G+GYLV
Sbjct: 529 FEFKVLAKDGGLPS-LQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLV 587
Query: 608 STVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTD 667
+ V+A D D GE+GR+TY++ +G D FEID +GE+RT F E EL+V D
Sbjct: 588 TVVKAEDYDEGENGRVTYDMTEG-DRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHD 646
Query: 668 HGKPTLSAVA-KLIIRSVSGSLPEGVPRVNGEQHHWDMSLPLIVTLSTISIILLAAMITI 726
HGK +LSA A LI S + E + VN +SL I+ L +I+ IL MI +
Sbjct: 647 HGKTSLSASALVLIYLSPALDAQESMGSVN-------LSLIFIIALGSIAGILFVTMIFV 699
Query: 727 AVKCKRENKEIRTYNCRIAEYSHPQLGGGKGKKKKINKNDIMLVQSEVEERNAMNVMNVV 786
A+KCKR+NKEIRTYNCRIAEYS+ KKKKI+KNDI LV +VEE + MNVV
Sbjct: 700 AIKCKRDNKEIRTYNCRIAEYSYGH-QKKSSKKKKISKNDIRLVPRDVEETDK---MNVV 755
Query: 787 SSPSLATSPMYFDY-QTRLPLSSPRSEVMYLKPASNNLTVPQGHAGCHTSFTGQGTNASE 845
S SL +S YFDY Q LPL RSE +L + N + H SF QG +
Sbjct: 756 SCSSLTSSLNYFDYHQQTLPLGCRRSESTFLNVENQNTRNTSANHIYHHSFNSQGPQQPD 815
Query: 846 TPATRMSIIQTDNFPAEPNYMGSRQQFVQSSSTFKDPERASLRDSGHGDSDQADSDQDTN 905
+ + +T+N+ + NY+ SR ++ SSTFKD E SL+DSGH +SDQ DS+ D
Sbjct: 816 LIINGVPLPETENYSFDSNYVNSRAHLIK-SSTFKDLEGNSLKDSGHEESDQTDSEHDVQ 874
Query: 906 KGSCCDMSVREALKMKTTSTKSQPLEQEPEECVNCTDECRVLGHSDRCWMPQFPAANQAE 965
+ CD +V + L TS SQ + + E +C +ECR+LGHSDRCWMP+ P +++
Sbjct: 875 RSLYCDTAVNDVLNTSVTSMGSQMPDHDQNEGFHCREECRILGHSDRCWMPRNPMPIRSK 934
Query: 966 NADYRTNLFVPTVEAN-VETETYETVNPTGKKTFCTFGKDKREHTILIANVKPYLKAKRA 1024
+ ++ N+ ++EA + E Y+ PT K+TF TFGKD +H A +P LK KR
Sbjct: 935 SPEHVRNIIALSIEATAADVEAYDDCGPT-KRTFATFGKDVSDHP---AEERPTLKGKRT 990
Query: 1025 L-----SPLLQEVPSASSSPTKACIEPCTSTKGSLDGCEAKP 1061
+ SP + V + + +A I P TS KP
Sbjct: 991 VDVTICSPKVNSVIREAGNGCEA-ISPVTSPLHLKSSLPTKP 1031
>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
Length = 1040
Score = 780 bits (2015), Expect = 0.0
Identities = 456/1084 (42%), Positives = 646/1084 (59%), Gaps = 124/1084 (11%)
Query: 10 LLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLEN 69
LLW L+Y+V EEQ GT +GNI D GL + G ++ + N
Sbjct: 9 LLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDL----GLDITKLSARG------FQTVPN 58
Query: 70 SAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFA-NDKEICMIKVEIQDINDN 128
S LD++ ++G+LY ++IDRE +C+ + C L LEVF N E+ +++E+ DINDN
Sbjct: 59 SRTPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDN 118
Query: 129 APSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGD 188
PSF + ++ISE+A PGTRFPL SA DPD G N LR Y +T + + F LDV+++GD
Sbjct: 119 PPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSY--FSLDVQTQGD 176
Query: 189 GTKFPELVIQKALDREQQNHHTLVLTALDGGE----------------PP---RSATVQI 229
G +F ELV++K LDREQQ H VLTA+DGG PP R+ T +
Sbjct: 177 GNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALL 236
Query: 230 NVKVIDSNDNSPVFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDR 289
++V+DSNDN P F+ P Y V LPEN+P GT+VI LNATD DEG NGEV+YSFSS++ R
Sbjct: 237 TIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPR 296
Query: 290 VRELFSIDPKTGLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAP 349
RELF + P+TG + V G LDYEE+ + ++ VQA+DLGPN +PAHCKV V+++D NDNAP
Sbjct: 297 ARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAP 356
Query: 350 SIGFVSVRQGALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGS 409
I F +V++ A+SE A PGTV+AL VTDRDS +NGQ+QC +LG
Sbjct: 357 EISFSTVKE-AVSEGAAPGTVVALFSVTDRDSEENGQVQCELLG---------------D 400
Query: 410 VPFKLEENYDNFYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNP 469
VPF+L+ ++ N+YT+VT+ PLDRE D Y +T+VARD G P L+++KS +++ D NDN
Sbjct: 401 VPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNA 460
Query: 470 PRFTKGLYVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNP 529
PRF++ +Y + V ENN+PG Y+ +V A D D G N ++YSIL I +S++TYVS+N
Sbjct: 461 PRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINS 520
Query: 530 TNGAIYALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIV--LPT 587
NG +YALRSF++EQ K F F+V A+D+G+P L NATV + ++D NDNAP IV LP
Sbjct: 521 ENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPG 580
Query: 588 LQNDTAELQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRT 647
A +PR+A GYL++ V A+D+D GE+ RLTY IV GN+ +LF +D +GE+RT
Sbjct: 581 RNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRT 640
Query: 648 LH--PFWEDVTPVVELVVKVTDHGKPTLSAVAKLIIRSVSGSL-PEG------------- 691
P D ELV++V DHG+P LS+ A L+++ V G++ P+G
Sbjct: 641 ARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQ 700
Query: 692 -VPRVNGEQHHWDMSLPLIVTLSTISIILLAAMITIAVKCKRENKEIRTYNCRIAE--YS 748
R G + D++L LI+ L ++S I L AMI +AV+C++E K++ Y C ++
Sbjct: 701 RPSRSGGGETSLDLTLILIIALGSVSFIFLLAMIVLAVRCQKE-KKLNIYTCLASDCCLC 759
Query: 749 HPQLGGG---------KGKKKKINKNDIMLVQSEVEERNAMNVMNVVSSPSLAT--SPMY 797
GGG + +KKK++K+DIMLVQS N V + S +
Sbjct: 760 CCCCGGGGSTCCGRQARARKKKLSKSDIMLVQSSNVPSNPAQV-PIEESGGFGSHHHNQN 818
Query: 798 FDYQTRLPLSSPRSEVMYLKPASNNLTVPQGHAGCHTSFTGQGTNASETPATRMSII--Q 855
+ YQ L S ++++M+LKP S + + H C TG T+ + SI+ +
Sbjct: 819 YCYQVCLTPESAKTDLMFLKPCSPSRSTDTEHNPCGAIVTGY-TDQQPDIISNGSILSNE 877
Query: 856 TDNFPAEPNYMGSRQQFVQSSSTFKDPERASLRDSGHGDSDQADSDQD-TNKGSCCDMSV 914
T + AE +Y+ R + V +SS F++ + S +DSGHGDS+Q DSD D TN+ M +
Sbjct: 878 TKHQRAELSYLVDRPRRV-NSSAFQEADIVSSKDSGHGDSEQGDSDHDATNRAQSAGMDL 936
Query: 915 REALKMKTTSTKSQPLEQEPEECVNCTDECRVLGHSDRCWMPQFPAANQAENADYRTNLF 974
NCT+EC+ LGHSDRCWMP F ++ + ADYR+NL
Sbjct: 937 FS----------------------NCTEECKALGHSDRCWMPSFVPSDGRQAADYRSNLH 974
Query: 975 VPTVEANVETETYET--VNPTGKKTFCTFGKDKREHTI--------LIANVK-----PYL 1019
VP +++ +TE +ET P +++F TFGK+K H+ L+ N + PYL
Sbjct: 975 VPGMDSVPDTEVFETPEAQPGAERSFSTFGKEKALHSTLERKELDGLLTNTRAPYKPPYL 1034
Query: 1020 KAKR 1023
KR
Sbjct: 1035 TRKR 1038
>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
Length = 896
Score = 681 bits (1758), Expect = 0.0
Identities = 385/881 (43%), Positives = 541/881 (61%), Gaps = 82/881 (9%)
Query: 10 LLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLEN 69
LLW L+Y+V EEQ GT +GNI D GL + G ++ + N
Sbjct: 9 LLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDL----GLDITKLSARG------FQTVPN 58
Query: 70 SAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFA-NDKEICMIKVEIQDINDN 128
S LD++ ++G+LY ++IDRE +C+ + C L LEVF N E+ +++E+ DINDN
Sbjct: 59 SRTPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDN 118
Query: 129 APSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGD 188
PSF + ++ISE+A PGTRFPL SA DPD G N LR Y +T + + F LDV+++GD
Sbjct: 119 PPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSY--FSLDVQTQGD 176
Query: 189 GTKFPELVIQKALDREQQNHHTLVLTALDGGE----------------PP---RSATVQI 229
G +F ELV++K LDREQQ H VLTA+DGG PP R+ T +
Sbjct: 177 GNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALL 236
Query: 230 NVKVIDSNDNSPVFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDR 289
++V+DSNDN P F+ P Y V LPEN+P GT+VI LNATD DEG NGEV+YSFSS++ R
Sbjct: 237 TIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPR 296
Query: 290 VRELFSIDPKTGLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAP 349
RELF + P+TG + V G LDYEE+ + ++ VQA+DLGPN +PAHCKV V+++D NDNAP
Sbjct: 297 ARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAP 356
Query: 350 SIGFVSVRQGALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGS 409
I F +V++ A+SE A PGTV+AL VTDRDS +NGQ+QC +LG
Sbjct: 357 EISFSTVKE-AVSEGAAPGTVVALFSVTDRDSEENGQVQCELLG---------------D 400
Query: 410 VPFKLEENYDNFYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNP 469
VPF+L+ ++ N+YT+VT+ PLDRE D Y +T+VARD G P L+++KS +++ D NDN
Sbjct: 401 VPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNA 460
Query: 470 PRFTKGLYVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNP 529
PRF++ +Y + V ENN+PG Y+ +V A D D G N ++YSIL I +S++TYVS+N
Sbjct: 461 PRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINS 520
Query: 530 TNGAIYALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIV--LPT 587
NG +YALRSF++EQ K F F+V A+D+G+P L NATV + ++D NDNAP IV LP
Sbjct: 521 ENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPG 580
Query: 588 LQNDTAELQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRT 647
A +PR+A GYL++ V A+D+D GE+ RLTY IV GN+ +LF +D +GE+RT
Sbjct: 581 RNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRT 640
Query: 648 LH--PFWEDVTPVVELVVKVTDHGKPTLSAVAKLIIRSVSGSL-PEG------------- 691
P D ELV++V DHG+P LS+ A L+++ V G++ P+G
Sbjct: 641 ARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQ 700
Query: 692 -VPRVNGEQHHWDMSLPLIVTLSTISIILLAAMITIAVKCKRENKEIRTYNCRIAE--YS 748
R G + D++L LI+ L ++S I L AMI +AV+C++E K++ Y C ++
Sbjct: 701 RPSRSGGGETSLDLTLILIIALGSVSFIFLLAMIVLAVRCQKE-KKLNIYTCLASDCCLC 759
Query: 749 HPQLGGG---------KGKKKKINKNDIMLVQSEVEERNAMNVMNVVSSPSLAT--SPMY 797
GGG + +KKK++K+DIMLVQS N V + S +
Sbjct: 760 CCCCGGGGSTCCGRQARARKKKLSKSDIMLVQSSNVPSNPAQV-PIEESGGFGSHHHNQN 818
Query: 798 FDYQTRLPLSSPRSEVMYLKPASNNLTVPQGHAGCHTSFTG 838
+ YQ L S ++++M+LKP S + + H C TG
Sbjct: 819 YCYQVCLTPESAKTDLMFLKPCSPSRSTDTEHNPCGAIVTG 859
>gi|14589929 protocadherin 18 precursor [Homo sapiens]
Length = 1135
Score = 659 bits (1701), Expect = 0.0
Identities = 428/1178 (36%), Positives = 633/1178 (53%), Gaps = 118/1178 (10%)
Query: 19 KNLNYSVPEEQGAGTVIGNIGRD-ARLQPGLPPAERGGGGRSKSGSYRVLENSAPHLLDV 77
KNL Y + EEQ G+VI + D A + LP + +R ++ LL V
Sbjct: 28 KNLKYRIYEEQRVGSVIARLSEDVADVLLKLP--------NPSTVRFRAMQRGNSPLLVV 79
Query: 78 DADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDKE---ICMIKVEIQDINDNAPSFSS 134
+ D+G + IDRE LC+ N C + +V E + I+VE+ DINDN+P FS
Sbjct: 80 NEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSR 139
Query: 135 DQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFPE 194
I ++ISE+AA GTR PL SA DPD GEN L TY L+ +D F ++V++R DG K+ E
Sbjct: 140 SLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSAND--FFNIEVRTRTDGAKYAE 197
Query: 195 LVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELPE 254
L++ + LDRE ++ + L LTA D G P RS + + + + DSNDNSP FE SY+++L E
Sbjct: 198 LIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLE 257
Query: 255 NAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEEN 314
N+P+GT+++DLNATD DEG NG+++YSFSS+V ++ E F ID + G + + +DYE
Sbjct: 258 NSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEIT 317
Query: 315 GMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGA-----LSEAAPPGT 369
EIDVQA+DLGPN IPAHCK+ +K++D NDN P I + G + E P T
Sbjct: 318 KSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDT 377
Query: 370 VIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRP 429
+ALVRV D+DSG NG++ C++ G G FKL++ Y+N Y ++T+
Sbjct: 378 FVALVRVQDKDSGLNGEIVCKLHGHGH---------------FKLQKTYENNYLILTNAT 422
Query: 430 LDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGE 489
LDRE + EY++T++A D G+P L++ K F ++I D NDNPP F + Y + ENN PG
Sbjct: 423 LDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGA 482
Query: 490 YLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFE 549
Y+ +V A DPDLG+NG V+Y+IL S I SI TYV+++P+NGAIYALR F+ E+
Sbjct: 483 YITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQIT 542
Query: 550 FKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRNAGLGYLVST 609
F V A+D G+P L SN TV +T++D NDN PV++ P L+N+TAE+ +P+ A G+ V+
Sbjct: 543 FVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHVTR 602
Query: 610 VRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVV--ELVVKVTD 667
+RA+D D G + L+ IV GN++++F IDP S +I T D P EL V + D
Sbjct: 603 IRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSM--DSVPYTEWELSVIIQD 660
Query: 668 HGKPTLSAVAKLIIRSVSGSLPEGV---PRVNGEQHHWDMSLPLIVTLSTISIILLAAMI 724
G P L K++++ + E V + Q D+S+ +I++L I +LL M+
Sbjct: 661 KGNPQLH--TKVLLKCMIFEYAESVTSTAMTSVSQASLDVSMIIIISLGAICAVLLVIMV 718
Query: 725 TIAVKCKRENKEIRTYNCRIAEYS---HPQLGGGKGKKKKINKNDIMLVQ--SEVEERNA 779
A +C RE K+ R+YNCR+AE + HP K ++I+K DI LV + +
Sbjct: 719 LFATRCNREKKDTRSYNCRVAESTYQHHP-----KRPSRQIHKGDITLVPTINGTLPIRS 773
Query: 780 MNVMNVVSSPSLATSPMYFDYQTRLPLSSPRSEVMYLKPASNNLTVPQGHAGCHTSFTGQ 839
+ + SSP+L M +R +S +S + +SN+ VP+ + T
Sbjct: 774 HHRSSPSSSPTLERGQM----GSRQSHNSHQSLNSLVTISSNH--VPENFSLELT----H 823
Query: 840 GTNASETPATRMSIIQTDNFPAEPNYMGSRQQFVQSSSTFKDPERASLRDSGHGDSDQAD 899
T A E + +S++ + P++ G++ +D ++ SL+DSG GDS+ D
Sbjct: 824 ATPAVEQVSQLLSMLHQGQYQPRPSFRGNKYS-RSYRYALQDMDKFSLKDSGRGDSEAGD 882
Query: 900 SDQDTNKGSCCDMSVREALKMKTTSTKSQPLEQEPEECVNCTDECRVLGHSDRCWMPQFP 959
SD D + S D + E + P CT+ECRVLGHSD+CWMP P
Sbjct: 883 SDYDLGRDSPIDRLLGEGFSDLFLTDGRIPAAMR-----LCTEECRVLGHSDQCWMPPLP 937
Query: 960 AANQAENADYRTNLFVPTVE-----------ANVETETYETVNPTGKKTFCTFGKDK--- 1005
+ ++DYR+N+F+P E ++E + + KK+F TFGKD
Sbjct: 938 ----SPSSDYRSNMFIPGEEFPTQPQQQHPHQSLEDDAQPADSGEKKKSFSTFGKDSPND 993
Query: 1006 -----REHTILIANVKPYLKAKRALSPLLQEVPSASSSPTKACIEPCTSTKGSLDGCEA- 1059
+ L++ + +R L P L S +E KG L
Sbjct: 994 EDTGDTSTSSLLSEMSSVF--QRLLPPSLDTYSECSEVDRSNSLE---RRKGPLPAKTVG 1048
Query: 1060 -KPGALAEASSQYLPTDSQYLSP------SKQPRDPPFMASDQMARVFADVHSRASRDSS 1112
G A A+S + + P S QP A +++ + +
Sbjct: 1049 YPQGVAAWAASTHFQNPTTNCGPPLGTHSSVQPSSKWLPAMEEIPENY---------EED 1099
Query: 1113 EMGAVLEQLDHPNRDLGRESVDAEEVVREIDKLLQDCR 1150
+ VL L+ D E +DA E+V EI+KLLQD R
Sbjct: 1100 DFDNVLNHLN----DGKHELMDASELVAEINKLLQDVR 1133
>gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor
[Homo sapiens]
Length = 1007
Score = 546 bits (1406), Expect = e-155
Identities = 346/916 (37%), Positives = 502/916 (54%), Gaps = 64/916 (6%)
Query: 1 MYLSICCCFLLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSK 60
+ L + LL P L YSVPEEQ G ++GN+ R L+ R G G +
Sbjct: 24 LLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLE-----LRRLGPGCLR 78
Query: 61 SGSYRVLENSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFA-NDKEICMIK 119
L +P L++D SG L+ +RIDRE+LC +C LSLEV A N + ++
Sbjct: 79 INH---LGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVE 135
Query: 120 VEIQDINDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLF 179
VEI DINDN+P F ++ +SE+ APG RF + SA DPD G N ++TY L+ +H F
Sbjct: 136 VEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEH--F 193
Query: 180 GLDVKSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDN 239
LD+K + +K ELV++K LDREQ H LVLTA+DGG P RS T QI+V+V+D+NDN
Sbjct: 194 ELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDN 253
Query: 240 SPVFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPK 299
SP F+ +Y V+L E++P GT+V+ LNA+D DEG NGE+ YS SSY DR R+LFSID
Sbjct: 254 SPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDAS 313
Query: 300 TGLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQG 359
TG +RV G LDYEE +I VQA D GP P+ HCKV V ++D NDNAP + +
Sbjct: 314 TGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDL-YS 372
Query: 360 ALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYD 419
+ E A P T++A++ V D+DSG N ++ G ++PF+L +
Sbjct: 373 PVPENATPNTIVAVLSVNDQDSGPNRKVSL---------------GLEATLPFRL-NGFG 416
Query: 420 NFYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVL 479
N YT+V PLDRE YN+T+ A DGG P L S ++ ++I D NDNPP F + Y +
Sbjct: 417 NSYTLVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSI 476
Query: 480 QVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRS 539
+ ENN+PG L +V A DPD +N V+YS+L I + + +YVS+N +G++YA+ S
Sbjct: 477 YIQENNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNS 536
Query: 540 FNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQ-VP 598
F++E+ + F V A+D G+P L S T V V+D+ND+AP I+ PT N +A + VP
Sbjct: 537 FDYEKFREFFVTVEAQDKGSPP-LSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVP 595
Query: 599 RNAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPV 658
R A GYLV+ V A+DSD G++ L Y + +D LF+++ +GEIRT ++
Sbjct: 596 RTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGST 655
Query: 659 VELVVKVTDHGKPTLS---AVAKLIIRSVSGSLPEGVPRVNGEQHHWDMSLPLIVTLSTI 715
L V V D+G+P+LS A+ ++ VS LP+ V + + +++L LI+ LST+
Sbjct: 656 FNLTVVVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTV 715
Query: 716 SIILLAAMITIAVKCKRENKEIRTYNCRIAEYSHPQLGGGKGKKKKINKNDIMLVQSEVE 775
S I L +I +++ I+ Y R Y GG G +++ + ++
Sbjct: 716 SFIFLLTIIILSI--------IKCY--RYTAYGTACCGGFCGVRERSPAELYKQANNNID 765
Query: 776 ER--NAMNV----MNVVSSPSLATSPMYFDYQTRLPLSSPRSEVMYLKPASNNLTVPQGH 829
R + + V + V + SL + + Y+ L S M+ + P G
Sbjct: 766 ARIPHGLKVQPHFIEVRGNGSLTKT---YCYKACLTAGSGSDTFMFYNTGAQTGPGPSGA 822
Query: 830 AGCHT---SFTGQ-GTNASETPATRMSIIQTDNFPAEPN----YMGSRQQFVQSSSTFKD 881
T + TGQ G NA + + + N P +PN Y S + + SS
Sbjct: 823 QAAVTDSRNLTGQSGQNAGNLIILKNEAV-SQNEPRQPNPDWRYSASLRAGMHSSVHL-- 879
Query: 882 PERASLRDSGHGDSDQ 897
E A + +G G DQ
Sbjct: 880 -EEAGILRAGPGGPDQ 894
>gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precursor
[Homo sapiens]
Length = 884
Score = 544 bits (1402), Expect = e-154
Identities = 310/738 (42%), Positives = 441/738 (59%), Gaps = 34/738 (4%)
Query: 1 MYLSICCCFLLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSK 60
+ L + LL P L YSVPEEQ G ++GN+ R L+ R G G +
Sbjct: 24 LLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLE-----LRRLGPGCLR 78
Query: 61 SGSYRVLENSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFA-NDKEICMIK 119
L +P L++D SG L+ +RIDRE+LC +C LSLEV A N + ++
Sbjct: 79 INH---LGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVE 135
Query: 120 VEIQDINDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLF 179
VEI DINDN+P F ++ +SE+ APG RF + SA DPD G N ++TY L+ +H F
Sbjct: 136 VEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEH--F 193
Query: 180 GLDVKSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDN 239
LD+K + +K ELV++K LDREQ H LVLTA+DGG P RS T QI+V+V+D+NDN
Sbjct: 194 ELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDN 253
Query: 240 SPVFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPK 299
SP F+ +Y V+L E++P GT+V+ LNA+D DEG NGE+ YS SSY DR R+LFSID
Sbjct: 254 SPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDAS 313
Query: 300 TGLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQG 359
TG +RV G LDYEE +I VQA D GP P+ HCKV V ++D NDNAP + +
Sbjct: 314 TGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDL-YS 372
Query: 360 ALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYD 419
+ E A P T++A++ V D+DSG N ++ G ++PF+L +
Sbjct: 373 PVPENATPNTIVAVLSVNDQDSGPNRKVSL---------------GLEATLPFRL-NGFG 416
Query: 420 NFYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVL 479
N YT+V PLDRE YN+T+ A DGG P L S ++ ++I D NDNPP F + Y +
Sbjct: 417 NSYTLVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSI 476
Query: 480 QVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRS 539
+ ENN+PG L +V A DPD +N V+YS+L I + + +YVS+N +G++YA+ S
Sbjct: 477 YIQENNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNS 536
Query: 540 FNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQ-VP 598
F++E+ + F V A+D G+P L S T V V+D+ND+AP I+ PT N +A + VP
Sbjct: 537 FDYEKFREFFVTVEAQDKGSPP-LSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVP 595
Query: 599 RNAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPV 658
R A GYLV+ V A+DSD G++ L Y + +D LF+++ +GEIRT ++
Sbjct: 596 RTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGST 655
Query: 659 VELVVKVTDHGKPTLS---AVAKLIIRSVSGSLPEGVPRVNGEQHHWDMSLPLIVTLSTI 715
L V V D+G+P+LS A+ ++ VS LP+ V + + +++L LI+ LST+
Sbjct: 656 FNLTVVVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTV 715
Query: 716 SIILLAAMITIA-VKCKR 732
S I L +I ++ +KC R
Sbjct: 716 SFIFLLTIIILSIIKCYR 733
>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 514 bits (1324), Expect = e-145
Identities = 300/734 (40%), Positives = 439/734 (59%), Gaps = 44/734 (5%)
Query: 11 LWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENS 70
LW T + YSVPEE G+ +G+I RD L+P AERG R++
Sbjct: 23 LWETGCT--QIRYSVPEELEKGSRVGDISRDLGLEPR-ELAERG---------VRIIPRG 70
Query: 71 APHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDK-EICMIKVEIQDINDNA 129
L ++ SG L T RIDRE LC KCQL+L++ DK +I ++VE++DINDNA
Sbjct: 71 RTQLFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNA 130
Query: 130 PSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDG 189
P F ++E+ ISENAA RFPL A DPD G+N L++Y L+ + H F L V++ DG
Sbjct: 131 PYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTH--FSLIVQNGADG 188
Query: 190 TKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYL 249
+K+PELV+++ALDRE++ H LVLTA DGG+P R+ T +I V V+D+NDN+P F P Y
Sbjct: 189 SKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYR 248
Query: 250 VELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNL 309
+PEN LGT ++ +NATD DEG N EV YSF YV D+ ++F +D +G I G L
Sbjct: 249 ASVPENLALGTQLLVVNATDPDEGVNAEVRYSFR-YVDDKAAQVFKLDCNSGTISTIGEL 307
Query: 310 DYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPGT 369
D+EE+G +++VQA D A KV + ++D NDNAP + S+ ++ E +P GT
Sbjct: 308 DHEESGFYQMEVQAMDNAG--YSARAKVLITVLDVNDNAPEVVLTSLAS-SVPENSPRGT 364
Query: 370 VIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRP 429
+IAL+ V D+DS +NGQ+ C + G ++PFKLE++Y N+Y++VTD
Sbjct: 365 LIALLNVNDQDSEENGQVICFIQG---------------NLPFKLEKSYGNYYSLVTDIV 409
Query: 430 LDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGE 489
LDRE YN+T+ A D G+PPL++ ++ + D NDNPP F + Y + ENN G
Sbjct: 410 LDREQVPSYNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGV 469
Query: 490 YLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFE 549
L SV A DPD +N ++YS+ + I S+ +YVS+N G +YAL SF++EQ + +
Sbjct: 470 SLVSVTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQ 529
Query: 550 FKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQND--TAELQVPRNAGLGYLV 607
KV+A+D+G P L SN ++ + VLD NDNAP I+ P L D T PR+A GYLV
Sbjct: 530 VKVMARDNGHPP-LSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLV 588
Query: 608 STVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTD 667
+ V A+D D G++ L+Y ++ ++ LF + +GE+RT + LVV V D
Sbjct: 589 TKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQD 648
Query: 668 HGKPTLSAVAKLIIRSVSGSLPE-----GVPRVNGEQHHWDMSLPLIVTLSTISIILLA- 721
HG+P LSA L + +V+ S+P+ G D++L L+V ++ +S + LA
Sbjct: 649 HGQPPLSATVTLTV-AVADSIPQVLADLGSLESPANSETSDLTLYLVVAVAAVSCVFLAF 707
Query: 722 AMITIAVKCKRENK 735
++ +A++ +R +K
Sbjct: 708 VILLLALRLRRWHK 721
>gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 514 bits (1324), Expect = e-145
Identities = 300/734 (40%), Positives = 439/734 (59%), Gaps = 44/734 (5%)
Query: 11 LWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENS 70
LW T + YSVPEE G+ +G+I RD L+P AERG R++
Sbjct: 23 LWETGCT--QIRYSVPEELEKGSRVGDISRDLGLEPR-ELAERG---------VRIIPRG 70
Query: 71 APHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDK-EICMIKVEIQDINDNA 129
L ++ SG L T RIDRE LC KCQL+L++ DK +I ++VE++DINDNA
Sbjct: 71 RTQLFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNA 130
Query: 130 PSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDG 189
P F ++E+ ISENAA RFPL A DPD G+N L++Y L+ + H F L V++ DG
Sbjct: 131 PYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTH--FSLIVQNGADG 188
Query: 190 TKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYL 249
+K+PELV+++ALDRE++ H LVLTA DGG+P R+ T +I V V+D+NDN+P F P Y
Sbjct: 189 SKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYR 248
Query: 250 VELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNL 309
+PEN LGT ++ +NATD DEG N EV YSF YV D+ ++F +D +G I G L
Sbjct: 249 ASVPENLALGTQLLVVNATDPDEGVNAEVRYSFR-YVDDKAAQVFKLDCNSGTISTIGEL 307
Query: 310 DYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPGT 369
D+EE+G +++VQA D A KV + ++D NDNAP + S+ ++ E +P GT
Sbjct: 308 DHEESGFYQMEVQAMDNAG--YSARAKVLITVLDVNDNAPEVVLTSLAS-SVPENSPRGT 364
Query: 370 VIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRP 429
+IAL+ V D+DS +NGQ+ C + G ++PFKLE++Y N+Y++VTD
Sbjct: 365 LIALLNVNDQDSEENGQVICFIQG---------------NLPFKLEKSYGNYYSLVTDIV 409
Query: 430 LDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGE 489
LDRE YN+T+ A D G+PPL++ ++ + D NDNPP F + Y + ENN G
Sbjct: 410 LDREQVPSYNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGV 469
Query: 490 YLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFE 549
L SV A DPD +N ++YS+ + I S+ +YVS+N G +YAL SF++EQ + +
Sbjct: 470 SLVSVTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQ 529
Query: 550 FKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQND--TAELQVPRNAGLGYLV 607
KV+A+D+G P L SN ++ + VLD NDNAP I+ P L D T PR+A GYLV
Sbjct: 530 VKVMARDNGHPP-LSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLV 588
Query: 608 STVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTD 667
+ V A+D D G++ L+Y ++ ++ LF + +GE+RT + LVV V D
Sbjct: 589 TKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQD 648
Query: 668 HGKPTLSAVAKLIIRSVSGSLPE-----GVPRVNGEQHHWDMSLPLIVTLSTISIILLA- 721
HG+P LSA L + +V+ S+P+ G D++L L+V ++ +S + LA
Sbjct: 649 HGQPPLSATVTLTV-AVADSIPQVLADLGSLESPANSETSDLTLYLVVAVAAVSCVFLAF 707
Query: 722 AMITIAVKCKRENK 735
++ +A++ +R +K
Sbjct: 708 VILLLALRLRRWHK 721
>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
[Homo sapiens]
Length = 936
Score = 510 bits (1313), Expect = e-144
Identities = 299/747 (40%), Positives = 433/747 (57%), Gaps = 46/747 (6%)
Query: 19 KNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAPHLLDVD 78
+ ++YS+PEE G+ +GNI +D L P AERG R++ L ++
Sbjct: 33 RQISYSIPEELEKGSFVGNISKDLGLAPR-ELAERG---------VRIVSRGRTQLFSLN 82
Query: 79 ADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDK-EICMIKVEIQDINDNAPSFSSDQI 137
SG L T RIDRE LC +A+C +S + D+ ++ I++E+ DINDNAP F ++ +
Sbjct: 83 PRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAPKFQAENL 142
Query: 138 EMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFPELVI 197
++ I+EN A G RFPL A DPD G N L++Y L+ + H F L V+SR +G K+PELV+
Sbjct: 143 DVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKH--FSLRVQSRANGVKYPELVL 200
Query: 198 QKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELPENAP 257
+ +LDRE++ H LVLTA DGG+P RS TV ++V V D+NDN+PVF P Y V +PEN P
Sbjct: 201 EHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLP 260
Query: 258 LGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEENGML 317
+GT ++ + ATD DEG NGEV YSF +PD F ++ TG I++ NLDYEE G
Sbjct: 261 VGTQLLTVTATDRDEGANGEVTYSFRK-LPDTQLLKFQLNKYTGEIKISENLDYEETGFY 319
Query: 318 EIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPGTVIALVRVT 377
EI++QA D G A +TV+ D NDN+P + S+ ++E +P GTV+AL+ V
Sbjct: 320 EIEIQAEDGGAYLATAKVLITVE--DVNDNSPELTITSLFS-PVTEDSPLGTVVALLNVH 376
Query: 378 DRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRPLDRETQDE 437
D DS +NGQ+ C +L +PFKLE++ D++Y +V R LDRE
Sbjct: 377 DLDSEQNGQVTCSILA---------------YLPFKLEKSIDSYYRLVIHRALDREQVSS 421
Query: 438 YNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGEYLGSVLAQ 497
YN+T+ A DGGSPPL++ F +++ D NDNPP F++ Y + ENN G + SV A
Sbjct: 422 YNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTAL 481
Query: 498 DPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKVLAKDS 557
DPD +N + YS+ I V + +Y+S+N G +YALRSF++EQ + +V A DS
Sbjct: 482 DPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDS 541
Query: 558 GAPAHLESNATVRVTVLDVNDNAPVIVLPTLQND--TAELQVPRNAGLGYLVSTVRALDS 615
G P L SN ++ + VLD NDNAP I+ P L D T PR+A GYLV+ V A+D
Sbjct: 542 GDPP-LSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDR 600
Query: 616 DFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTDHGKPTLSA 675
D G++ L+Y ++ ++ LF + +GE+RT + LVV V DHG+P LSA
Sbjct: 601 DSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSA 660
Query: 676 VAKLIIRSVSGSLPE-----GVPRVNGEQHHWDMSLPLIVTLSTISIILLAAMITIAVKC 730
L + +V+ S+P+ G D++L L+V ++ +S + LA +I +
Sbjct: 661 TVTLTV-AVADSIPQVLADLGSFESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHR 719
Query: 731 KRENKEIRTYNCRIAEYSHPQLGGGKG 757
R R + R+ + S L G G
Sbjct: 720 LR-----RWHKSRLLQASGGGLTGVSG 741
Score = 161 bits (408), Expect = 3e-39
Identities = 124/464 (26%), Positives = 209/464 (45%), Gaps = 48/464 (10%)
Query: 13 APALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAP 72
AP TL SVPE GT + + R + G G + S+R L ++
Sbjct: 243 APVFTLPEYRVSVPENLPVGTQLLTVTATDR--------DEGANG-EVTYSFRKLPDTQL 293
Query: 73 HLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFAND----KEICMIKVEIQDINDN 128
++ +G + + +D E + +E+ A D + + ++D+NDN
Sbjct: 294 LKFQLNKYTGEIKISENLDYEETGFY------EIEIQAEDGGAYLATAKVLITVEDVNDN 347
Query: 129 APSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGD 188
+P + + ++E++ GT L + HD D+ +NG T + L L K
Sbjct: 348 SPELTITSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSI------LAYLPFKLEKS 401
Query: 189 GTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSY 248
+ LVI +ALDREQ + + + +TA DGG PP S ++V D NDN P F SY
Sbjct: 402 IDSYYRLVIHRALDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSY 461
Query: 249 LVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRV--RELFSIDPKTGLIRVK 306
+PEN G + + A D D N +++YS + V SI+ TG++
Sbjct: 462 FTYIPENNARGASIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYAL 521
Query: 307 GNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALS---- 362
+ DYE+ L++ V A D G P+ ++ +++ ++D+NDNAP I + ++ +
Sbjct: 522 RSFDYEQFHELQMQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVEL 581
Query: 363 --EAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDN 420
+A PG ++ V DRDSG+N L R+L G F + E+
Sbjct: 582 APRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPG------------LFAVGEHTGE 629
Query: 421 FYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILD 464
T LDR+ + ++ + +D G PPL++T + + + D
Sbjct: 630 VRT--ARALLDRDALKQ-SLVVAVQDHGQPPLSATVTLTVAVAD 670
>gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precursor
[Homo sapiens]
Length = 850
Score = 510 bits (1313), Expect = e-144
Identities = 299/747 (40%), Positives = 433/747 (57%), Gaps = 46/747 (6%)
Query: 19 KNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAPHLLDVD 78
+ ++YS+PEE G+ +GNI +D L P AERG R++ L ++
Sbjct: 33 RQISYSIPEELEKGSFVGNISKDLGLAPR-ELAERG---------VRIVSRGRTQLFSLN 82
Query: 79 ADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDK-EICMIKVEIQDINDNAPSFSSDQI 137
SG L T RIDRE LC +A+C +S + D+ ++ I++E+ DINDNAP F ++ +
Sbjct: 83 PRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAPKFQAENL 142
Query: 138 EMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFPELVI 197
++ I+EN A G RFPL A DPD G N L++Y L+ + H F L V+SR +G K+PELV+
Sbjct: 143 DVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKH--FSLRVQSRANGVKYPELVL 200
Query: 198 QKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELPENAP 257
+ +LDRE++ H LVLTA DGG+P RS TV ++V V D+NDN+PVF P Y V +PEN P
Sbjct: 201 EHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLP 260
Query: 258 LGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEENGML 317
+GT ++ + ATD DEG NGEV YSF +PD F ++ TG I++ NLDYEE G
Sbjct: 261 VGTQLLTVTATDRDEGANGEVTYSFRK-LPDTQLLKFQLNKYTGEIKISENLDYEETGFY 319
Query: 318 EIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPGTVIALVRVT 377
EI++QA D G A +TV+ D NDN+P + S+ ++E +P GTV+AL+ V
Sbjct: 320 EIEIQAEDGGAYLATAKVLITVE--DVNDNSPELTITSLFS-PVTEDSPLGTVVALLNVH 376
Query: 378 DRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRPLDRETQDE 437
D DS +NGQ+ C +L +PFKLE++ D++Y +V R LDRE
Sbjct: 377 DLDSEQNGQVTCSILA---------------YLPFKLEKSIDSYYRLVIHRALDREQVSS 421
Query: 438 YNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGEYLGSVLAQ 497
YN+T+ A DGGSPPL++ F +++ D NDNPP F++ Y + ENN G + SV A
Sbjct: 422 YNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTAL 481
Query: 498 DPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKVLAKDS 557
DPD +N + YS+ I V + +Y+S+N G +YALRSF++EQ + +V A DS
Sbjct: 482 DPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDS 541
Query: 558 GAPAHLESNATVRVTVLDVNDNAPVIVLPTLQND--TAELQVPRNAGLGYLVSTVRALDS 615
G P L SN ++ + VLD NDNAP I+ P L D T PR+A GYLV+ V A+D
Sbjct: 542 GDPP-LSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDR 600
Query: 616 DFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTDHGKPTLSA 675
D G++ L+Y ++ ++ LF + +GE+RT + LVV V DHG+P LSA
Sbjct: 601 DSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSA 660
Query: 676 VAKLIIRSVSGSLPE-----GVPRVNGEQHHWDMSLPLIVTLSTISIILLAAMITIAVKC 730
L + +V+ S+P+ G D++L L+V ++ +S + LA +I +
Sbjct: 661 TVTLTV-AVADSIPQVLADLGSFESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHR 719
Query: 731 KRENKEIRTYNCRIAEYSHPQLGGGKG 757
R R + R+ + S L G G
Sbjct: 720 LR-----RWHKSRLLQASGGGLTGVSG 741
Score = 161 bits (408), Expect = 3e-39
Identities = 124/464 (26%), Positives = 209/464 (45%), Gaps = 48/464 (10%)
Query: 13 APALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAP 72
AP TL SVPE GT + + R + G G + S+R L ++
Sbjct: 243 APVFTLPEYRVSVPENLPVGTQLLTVTATDR--------DEGANG-EVTYSFRKLPDTQL 293
Query: 73 HLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFAND----KEICMIKVEIQDINDN 128
++ +G + + +D E + +E+ A D + + ++D+NDN
Sbjct: 294 LKFQLNKYTGEIKISENLDYEETGFY------EIEIQAEDGGAYLATAKVLITVEDVNDN 347
Query: 129 APSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGD 188
+P + + ++E++ GT L + HD D+ +NG T + L L K
Sbjct: 348 SPELTITSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSI------LAYLPFKLEKS 401
Query: 189 GTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSY 248
+ LVI +ALDREQ + + + +TA DGG PP S ++V D NDN P F SY
Sbjct: 402 IDSYYRLVIHRALDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSY 461
Query: 249 LVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRV--RELFSIDPKTGLIRVK 306
+PEN G + + A D D N +++YS + V SI+ TG++
Sbjct: 462 FTYIPENNARGASIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYAL 521
Query: 307 GNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALS---- 362
+ DYE+ L++ V A D G P+ ++ +++ ++D+NDNAP I + ++ +
Sbjct: 522 RSFDYEQFHELQMQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVEL 581
Query: 363 --EAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDN 420
+A PG ++ V DRDSG+N L R+L G F + E+
Sbjct: 582 APRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPG------------LFAVGEHTGE 629
Query: 421 FYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILD 464
T LDR+ + ++ + +D G PPL++T + + + D
Sbjct: 630 VRT--ARALLDRDALKQ-SLVVAVQDHGQPPLSATVTLTVAVAD 670
>gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precursor
[Homo sapiens]
Length = 871
Score = 509 bits (1311), Expect = e-144
Identities = 292/732 (39%), Positives = 417/732 (56%), Gaps = 41/732 (5%)
Query: 9 FLLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLE 68
FL + + Y VPEE GT +GN+ +D L A R +V
Sbjct: 19 FLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARR----------LQVAG 68
Query: 69 NSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLE-VFANDKEICMIKVEIQDIND 127
VD DSG L K IDRE+LC +A C + LE V E+ +VEI D+ND
Sbjct: 69 EVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVND 128
Query: 128 NAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRG 187
+AP F Q++++I E A PG RFPL A D D G N + +Y L+ ++H F LDVK R
Sbjct: 129 HAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEH--FALDVKKRS 186
Query: 188 DGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPS 247
DG+ PEL+++K LDRE+Q+ + LVLTA+DGG PPRS T ++ V V+D NDN+P F+ S
Sbjct: 187 DGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSS 246
Query: 248 YLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKG 307
Y + + E+AP G V+I LNA+D D GP+G V + FS + PDRVR LFS+ P TG + + G
Sbjct: 247 YRISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLG 306
Query: 308 NLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPP 367
LD+E E DV+ARD G + HC + V L+D NDNAP I V+ G L E+A P
Sbjct: 307 PLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYI-TVTSELGTLPESAEP 365
Query: 368 GTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTD 427
GTV+AL+ V D DSG NG + R+ +PF L+ + N +++VT
Sbjct: 366 GTVVALISVQDPDSGSNGDVSLRI---------------PDHLPFALKSAFRNQFSLVTA 410
Query: 428 RPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIP 487
PLDRE + Y++ + A D G+PPL++ ++ + I D NDNPP F + + + V ENN P
Sbjct: 411 GPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRP 470
Query: 488 GEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKA 547
G+ L S+ A DPD G N +SYS+L DVS +++S+NP GA++A RSF++EQT+
Sbjct: 471 GDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQT 530
Query: 548 FEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQ-NDTAELQVPRNAGLGYL 606
+F+V A+D G P L S TVR+ VLD+NDNAP ++ P + +P + G G+L
Sbjct: 531 LQFEVQARDRGNPP-LSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHL 589
Query: 607 VSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVT 666
++ V A+D D G + ++Y++++ D LF + +GE+RT P D+ P +LV+ V
Sbjct: 590 ITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPP-QKLVIVVK 648
Query: 667 DHGKPTLSAVAKLII------RSVSGSLPEGVPRVNGEQHHWDMSLPLIVTLSTISIILL 720
D G P LS L++ V L E GE ++L L V+L I +
Sbjct: 649 DSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAPREGESR---LTLYLAVSLVAICFVSF 705
Query: 721 AAMITIAVKCKR 732
+ + + KC R
Sbjct: 706 GSFVALLSKCLR 717
>gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precursor
[Homo sapiens]
Length = 938
Score = 509 bits (1311), Expect = e-144
Identities = 292/732 (39%), Positives = 417/732 (56%), Gaps = 41/732 (5%)
Query: 9 FLLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLE 68
FL + + Y VPEE GT +GN+ +D L A R +V
Sbjct: 19 FLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARR----------LQVAG 68
Query: 69 NSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLE-VFANDKEICMIKVEIQDIND 127
VD DSG L K IDRE+LC +A C + LE V E+ +VEI D+ND
Sbjct: 69 EVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVND 128
Query: 128 NAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRG 187
+AP F Q++++I E A PG RFPL A D D G N + +Y L+ ++H F LDVK R
Sbjct: 129 HAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEH--FALDVKKRS 186
Query: 188 DGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPS 247
DG+ PEL+++K LDRE+Q+ + LVLTA+DGG PPRS T ++ V V+D NDN+P F+ S
Sbjct: 187 DGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSS 246
Query: 248 YLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKG 307
Y + + E+AP G V+I LNA+D D GP+G V + FS + PDRVR LFS+ P TG + + G
Sbjct: 247 YRISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLG 306
Query: 308 NLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPP 367
LD+E E DV+ARD G + HC + V L+D NDNAP I V+ G L E+A P
Sbjct: 307 PLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYI-TVTSELGTLPESAEP 365
Query: 368 GTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTD 427
GTV+AL+ V D DSG NG + R+ +PF L+ + N +++VT
Sbjct: 366 GTVVALISVQDPDSGSNGDVSLRI---------------PDHLPFALKSAFRNQFSLVTA 410
Query: 428 RPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIP 487
PLDRE + Y++ + A D G+PPL++ ++ + I D NDNPP F + + + V ENN P
Sbjct: 411 GPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRP 470
Query: 488 GEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKA 547
G+ L S+ A DPD G N +SYS+L DVS +++S+NP GA++A RSF++EQT+
Sbjct: 471 GDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQT 530
Query: 548 FEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQ-NDTAELQVPRNAGLGYL 606
+F+V A+D G P L S TVR+ VLD+NDNAP ++ P + +P + G G+L
Sbjct: 531 LQFEVQARDRGNPP-LSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHL 589
Query: 607 VSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVT 666
++ V A+D D G + ++Y++++ D LF + +GE+RT P D+ P +LV+ V
Sbjct: 590 ITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPP-QKLVIVVK 648
Query: 667 DHGKPTLSAVAKLII------RSVSGSLPEGVPRVNGEQHHWDMSLPLIVTLSTISIILL 720
D G P LS L++ V L E GE ++L L V+L I +
Sbjct: 649 DSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAPREGESR---LTLYLAVSLVAICFVSF 705
Query: 721 AAMITIAVKCKR 732
+ + + KC R
Sbjct: 706 GSFVALLSKCLR 717
>gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 508 bits (1308), Expect = e-143
Identities = 295/738 (39%), Positives = 432/738 (58%), Gaps = 42/738 (5%)
Query: 7 CCFLLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRV 66
C L + + + YSV EEQ G+V+GNI +D L P AERG R+
Sbjct: 17 CLLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPR-ELAERG---------VRI 66
Query: 67 LENSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDK-EICMIKVEIQDI 125
+ L ++ SG L T RIDRE LC + C +LE+ D +I ++VEI D+
Sbjct: 67 VSRGRTQLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDV 126
Query: 126 NDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKS 185
NDN PSF ++Q E+ ++EN PG RFPL A DPD G N L+ Y L + +G F LDV+S
Sbjct: 127 NDNPPSFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQL--NSNGYFSLDVQS 184
Query: 186 RGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEA 245
DG K+PELV+++ALDRE++ H LVLTA DGG+P RS T +I + ++D+NDN+PVF
Sbjct: 185 GADGIKYPELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQ 244
Query: 246 PSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRV 305
P Y V + EN P+GT ++ + ATD DEG NG+V YSF V D++ +LF ++ +G I +
Sbjct: 245 PEYHVSVRENVPVGTRLLTVKATDPDEGANGDVTYSFRK-VRDKISQLFQLNSLSGDITI 303
Query: 306 KGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAA 365
G LDYE++G +IDV+A D GP + A KV V ++D NDNAP + S+ ++ E++
Sbjct: 304 LGGLDYEDSGFYDIDVEAHD-GPG-LRARSKVLVTVLDENDNAPEVTVTSLTS-SVQESS 360
Query: 366 PPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVV 425
PGTVIAL V D DSG NG + C + ++PF LE+ Y N+Y ++
Sbjct: 361 SPGTVIALFNVHDSDSGGNGLVTCSI---------------PDNLPFTLEKTYGNYYRLL 405
Query: 426 TDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENN 485
T R LDRE EYN+T+ A D G+PPL++ +++++D NDNPP F Y + ENN
Sbjct: 406 THRTLDREEVSEYNITVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENN 465
Query: 486 IPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQT 545
G + S+ AQDPD G N ++YS+ + +YVS+N G +YAL SF++EQ
Sbjct: 466 PRGASILSMTAQDPDSGDNARITYSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQF 525
Query: 546 KAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQND--TAELQVPRNAGL 603
+ + + A DSG P L SN ++ + VLD NDN P I+ PT D T PR+A
Sbjct: 526 RDLQLLMTASDSGDPP-LSSNVSLSLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADS 584
Query: 604 GYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVV 663
GYLV+ V A+D D G++ L+Y ++ ++ LF + +GE+RT + LVV
Sbjct: 585 GYLVTKVVAVDRDSGQNAWLSYSLLKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVV 644
Query: 664 KVTDHGKPTLSAVAKLIIRSVSGSLPE-----GVPRVNGEQHHWDMSLPLIVTLSTISII 718
V DHG+P LSA L + +V+ S+P+ G + + + ++L L+V ++ +S +
Sbjct: 645 VVQDHGQPPLSATVTLTV-AVADSIPDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCV 703
Query: 719 LLA-AMITIAVKCKRENK 735
LA + +A+K +R +K
Sbjct: 704 FLAFVTVLLALKLRRWHK 721
>gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 508 bits (1308), Expect = e-143
Identities = 295/738 (39%), Positives = 432/738 (58%), Gaps = 42/738 (5%)
Query: 7 CCFLLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRV 66
C L + + + YSV EEQ G+V+GNI +D L P AERG R+
Sbjct: 17 CLLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPR-ELAERG---------VRI 66
Query: 67 LENSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDK-EICMIKVEIQDI 125
+ L ++ SG L T RIDRE LC + C +LE+ D +I ++VEI D+
Sbjct: 67 VSRGRTQLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDV 126
Query: 126 NDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKS 185
NDN PSF ++Q E+ ++EN PG RFPL A DPD G N L+ Y L + +G F LDV+S
Sbjct: 127 NDNPPSFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQL--NSNGYFSLDVQS 184
Query: 186 RGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEA 245
DG K+PELV+++ALDRE++ H LVLTA DGG+P RS T +I + ++D+NDN+PVF
Sbjct: 185 GADGIKYPELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQ 244
Query: 246 PSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRV 305
P Y V + EN P+GT ++ + ATD DEG NG+V YSF V D++ +LF ++ +G I +
Sbjct: 245 PEYHVSVRENVPVGTRLLTVKATDPDEGANGDVTYSFRK-VRDKISQLFQLNSLSGDITI 303
Query: 306 KGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAA 365
G LDYE++G +IDV+A D GP + A KV V ++D NDNAP + S+ ++ E++
Sbjct: 304 LGGLDYEDSGFYDIDVEAHD-GPG-LRARSKVLVTVLDENDNAPEVTVTSLTS-SVQESS 360
Query: 366 PPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVV 425
PGTVIAL V D DSG NG + C + ++PF LE+ Y N+Y ++
Sbjct: 361 SPGTVIALFNVHDSDSGGNGLVTCSI---------------PDNLPFTLEKTYGNYYRLL 405
Query: 426 TDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENN 485
T R LDRE EYN+T+ A D G+PPL++ +++++D NDNPP F Y + ENN
Sbjct: 406 THRTLDREEVSEYNITVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENN 465
Query: 486 IPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQT 545
G + S+ AQDPD G N ++YS+ + +YVS+N G +YAL SF++EQ
Sbjct: 466 PRGASILSMTAQDPDSGDNARITYSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQF 525
Query: 546 KAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQND--TAELQVPRNAGL 603
+ + + A DSG P L SN ++ + VLD NDN P I+ PT D T PR+A
Sbjct: 526 RDLQLLMTASDSGDPP-LSSNVSLSLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADS 584
Query: 604 GYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVV 663
GYLV+ V A+D D G++ L+Y ++ ++ LF + +GE+RT + LVV
Sbjct: 585 GYLVTKVVAVDRDSGQNAWLSYSLLKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVV 644
Query: 664 KVTDHGKPTLSAVAKLIIRSVSGSLPE-----GVPRVNGEQHHWDMSLPLIVTLSTISII 718
V DHG+P LSA L + +V+ S+P+ G + + + ++L L+V ++ +S +
Sbjct: 645 VVQDHGQPPLSATVTLTV-AVADSIPDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCV 703
Query: 719 LLA-AMITIAVKCKRENK 735
LA + +A+K +R +K
Sbjct: 704 FLAFVTVLLALKLRRWHK 721
>gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precursor
[Homo sapiens]
Length = 837
Score = 506 bits (1303), Expect = e-143
Identities = 298/732 (40%), Positives = 426/732 (58%), Gaps = 41/732 (5%)
Query: 3 LSICCCFLLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSG 62
L + C FL + + YSVPEE G+ +GNI +D L+P A+RG
Sbjct: 14 LLLLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPR-ELAKRG-------- 64
Query: 63 SYRVLENSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDK-EICMIKVE 121
R++ L V+ SG L T RIDRE LC + C L++E+ D +I ++VE
Sbjct: 65 -VRIVSRGKTQLFAVNPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVE 123
Query: 122 IQDINDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGL 181
I DINDNAPSF D++E+ +SE+A PG RF L +A DPD G N L++Y L+ +++ F L
Sbjct: 124 IIDINDNAPSFQEDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNY--FSL 181
Query: 182 DVKSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSP 241
++ R DG K PELV++ +LDRE++ H L+LTALDGG+P R V I V V+D ND+ P
Sbjct: 182 QLRGRTDGAKNPELVLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIP 241
Query: 242 VFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTG 301
+F Y V +PEN GT V+ +NATD DEG NGEV+YSF + + + E+F +D +TG
Sbjct: 242 MFTQSVYRVSVPENISSGTRVLMVNATDPDEGINGEVMYSFRN-MESKASEIFQLDSQTG 300
Query: 302 LIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGAL 361
++V+G+LD+E+ E+++Q +D G +TV +D NDNAP I S L
Sbjct: 301 EVQVRGSLDFEKYRFYEMEIQGQDGGGLFTTTTMLITV--VDVNDNAPEITITSSINSIL 358
Query: 362 SEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNF 421
E +PPGTVIAL+ V D+DSG+NGQ+ C + +PFKLE+ Y N+
Sbjct: 359 -ENSPPGTVIALLNVQDQDSGENGQVSCFI---------------PNHLPFKLEKTYGNY 402
Query: 422 YTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQV 481
Y ++T R LDRE YN+T+ A D GSPPL++ + + D+NDNPP F Y +
Sbjct: 403 YKLITSRVLDRELVQSYNITLTATDQGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYI 462
Query: 482 HENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFN 541
ENN G + SV A DPD QN V+YS+ + V + +YVS+N G +YAL+SF+
Sbjct: 463 PENNPRGASIFSVTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSINSNTGVLYALQSFD 522
Query: 542 FEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQND--TAELQVPR 599
+EQ + E +V+A+DSG P L SN ++ + VLD NDNAP I+ P L D T PR
Sbjct: 523 YEQFRDLELRVIARDSGDPP-LSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPR 581
Query: 600 NAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVV 659
+A GYLV+ V A+D D G++ L+Y ++ ++ LF + +GE+RT +
Sbjct: 582 SAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQ 641
Query: 660 ELVVKVTDHGKPTLSAVAKLIIRSVSGSLPE-----GVPRVNGEQHHWDMSLPLIVTLST 714
LVV V DHG+P LSA L + +V+ S+PE G D+SL L+V ++
Sbjct: 642 SLVVAVQDHGQPPLSATVTLTV-AVADSIPEVLADLGSLESLANSETSDLSLYLVVAVAA 700
Query: 715 ISIILLAAMITI 726
+S I L +I +
Sbjct: 701 VSCIFLVFVIVL 712
>gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precursor
[Homo sapiens]
Length = 935
Score = 506 bits (1303), Expect = e-143
Identities = 298/732 (40%), Positives = 426/732 (58%), Gaps = 41/732 (5%)
Query: 3 LSICCCFLLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSG 62
L + C FL + + YSVPEE G+ +GNI +D L+P A+RG
Sbjct: 14 LLLLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPR-ELAKRG-------- 64
Query: 63 SYRVLENSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDK-EICMIKVE 121
R++ L V+ SG L T RIDRE LC + C L++E+ D +I ++VE
Sbjct: 65 -VRIVSRGKTQLFAVNPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVE 123
Query: 122 IQDINDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGL 181
I DINDNAPSF D++E+ +SE+A PG RF L +A DPD G N L++Y L+ +++ F L
Sbjct: 124 IIDINDNAPSFQEDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNY--FSL 181
Query: 182 DVKSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSP 241
++ R DG K PELV++ +LDRE++ H L+LTALDGG+P R V I V V+D ND+ P
Sbjct: 182 QLRGRTDGAKNPELVLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIP 241
Query: 242 VFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTG 301
+F Y V +PEN GT V+ +NATD DEG NGEV+YSF + + + E+F +D +TG
Sbjct: 242 MFTQSVYRVSVPENISSGTRVLMVNATDPDEGINGEVMYSFRN-MESKASEIFQLDSQTG 300
Query: 302 LIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGAL 361
++V+G+LD+E+ E+++Q +D G +TV +D NDNAP I S L
Sbjct: 301 EVQVRGSLDFEKYRFYEMEIQGQDGGGLFTTTTMLITV--VDVNDNAPEITITSSINSIL 358
Query: 362 SEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNF 421
E +PPGTVIAL+ V D+DSG+NGQ+ C + +PFKLE+ Y N+
Sbjct: 359 -ENSPPGTVIALLNVQDQDSGENGQVSCFI---------------PNHLPFKLEKTYGNY 402
Query: 422 YTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQV 481
Y ++T R LDRE YN+T+ A D GSPPL++ + + D+NDNPP F Y +
Sbjct: 403 YKLITSRVLDRELVQSYNITLTATDQGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYI 462
Query: 482 HENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFN 541
ENN G + SV A DPD QN V+YS+ + V + +YVS+N G +YAL+SF+
Sbjct: 463 PENNPRGASIFSVTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSINSNTGVLYALQSFD 522
Query: 542 FEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQND--TAELQVPR 599
+EQ + E +V+A+DSG P L SN ++ + VLD NDNAP I+ P L D T PR
Sbjct: 523 YEQFRDLELRVIARDSGDPP-LSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPR 581
Query: 600 NAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVV 659
+A GYLV+ V A+D D G++ L+Y ++ ++ LF + +GE+RT +
Sbjct: 582 SAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQ 641
Query: 660 ELVVKVTDHGKPTLSAVAKLIIRSVSGSLPE-----GVPRVNGEQHHWDMSLPLIVTLST 714
LVV V DHG+P LSA L + +V+ S+PE G D+SL L+V ++
Sbjct: 642 SLVVAVQDHGQPPLSATVTLTV-AVADSIPEVLADLGSLESLANSETSDLSLYLVVAVAA 700
Query: 715 ISIILLAAMITI 726
+S I L +I +
Sbjct: 701 VSCIFLVFVIVL 712
>gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 504 bits (1297), Expect = e-142
Identities = 292/722 (40%), Positives = 427/722 (59%), Gaps = 42/722 (5%)
Query: 23 YSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAPHLLDVDADSG 82
YSV EE G+ +G+I +D L+P AERG R++ L ++ SG
Sbjct: 33 YSVSEETDKGSFVGDIAKDLGLEPR-ELAERG---------VRIISRGRTQLFALNQRSG 82
Query: 83 LLYTKQRIDRESLCRHNAKCQLSLEVFANDK-EICMIKVEIQDINDNAPSFSSDQIEMDI 141
L T RIDRE +C +A+C ++ + DK + I VEI DINDN P F +++I + I
Sbjct: 83 SLVTAGRIDREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPRFLTEEINVKI 142
Query: 142 SENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFPELVIQKAL 201
EN APG RFPL+ A DPD G N L++Y L+ + H F L V+S D TK+PELV+++ L
Sbjct: 143 MENTAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRH--FSLAVQSGDDETKYPELVLERVL 200
Query: 202 DREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELPENAPLGTV 261
DRE++ H LVLTA DGG+PPRS+T I V V+D ND++PVF P Y V +PEN P+GT
Sbjct: 201 DREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTR 260
Query: 262 VIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEENGMLEIDV 321
++ ++A D DEG NGEV YSF P ++ ++F ++ TG I LDYEE E++V
Sbjct: 261 LLTVHAIDLDEGVNGEVTYSFRKITP-KLPKMFHLNSLTGEISTLEGLDYEETAFYEMEV 319
Query: 322 QARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPGTVIALVRVTDRDS 381
QA+D GP + KV + ++D NDNAP + S+ ++ E P GTVIAL + DRDS
Sbjct: 320 QAQD-GPGSL-TKAKVLITVLDVNDNAPEVTMTSL-SSSIPEDTPLGTVIALFYLQDRDS 376
Query: 382 GKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRPLDRETQDEYNVT 441
GKNG++ C + ++PFKLE++ DN+Y +VT + LDRET YN+T
Sbjct: 377 GKNGEVTCTI---------------PENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNIT 421
Query: 442 IVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGEYLGSVLAQDPDL 501
+ A DGG+PPL+ +++ D NDNPP F Y + + ENN G + V AQD D
Sbjct: 422 LKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDS 481
Query: 502 GQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKVLAKDSGAPA 561
N ++YS+ I + +YVS+N G +YAL+SF++EQ + + +V A DSG P
Sbjct: 482 EDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPP 541
Query: 562 HLESNATVRVTVLDVNDNAPVIVLPTLQND--TAELQVPRNAGLGYLVSTVRALDSDFGE 619
L SN ++ + VLD NDN P I+ P L D T PR+A GYLV+ V A+D D G+
Sbjct: 542 -LSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQ 600
Query: 620 SGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTDHGKPTLSAVAKL 679
+ L+Y ++ ++ LF + +GE+RT + LVV V DHG+P LSA L
Sbjct: 601 NAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTL 660
Query: 680 IIRSVSGSLPE-----GVPRVNGEQHHWDMSLPLIVTLSTISIILLA-AMITIAVKCKRE 733
+ +V+ S+PE G + +++D++L L+V ++T+S + LA ++ +A++ +R
Sbjct: 661 TV-AVADSIPEVLADLGSLEPSDGPYNYDLTLYLVVAVATVSCVFLAFVLVLLALRLRRW 719
Query: 734 NK 735
+K
Sbjct: 720 HK 721
Score = 93.2 bits (230), Expect = 1e-18
Identities = 93/342 (27%), Positives = 150/342 (43%), Gaps = 30/342 (8%)
Query: 13 APALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAP 72
AP +T+ +L+ S+PE+ GTVI R G++ + + EN P
Sbjct: 344 APEVTMTSLSSSIPEDTPLGTVIALFYLQDR-----------DSGKNGEVTCTIPEN-LP 391
Query: 73 HLLDVDADSGL-LYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKVEIQDINDNAPS 131
L+ D+ L T + +DRE+L +N + + I +++ D NDN P+
Sbjct: 392 FKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPT 451
Query: 132 FSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSR-GDGT 190
F + I+EN G L +A D D+ +N TY L D + G V S +
Sbjct: 452 FPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAEDT--IQGAPVSSYVSINS 509
Query: 191 KFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLV 250
L ++ D EQ L +TA D G+PP S+ + +++ V+D NDN P P+
Sbjct: 510 DTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPT 569
Query: 251 E-------LPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRE--LFSIDPKTG 301
+ P +A G +V + A D D G N ++ SY+ + E LF++ TG
Sbjct: 570 DGSTGMELAPRSAEPGYLVTKVVAVDKDSGQN-----AWLSYLLLKASEPGLFAVGLYTG 624
Query: 302 LIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLID 343
+R L + + V +D G P+ A +TV + D
Sbjct: 625 EVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 666
>gi|14196477 protocadherin gamma subfamily A, 7 isoform 2 precursor
[Homo sapiens]
Length = 817
Score = 504 bits (1297), Expect = e-142
Identities = 292/722 (40%), Positives = 427/722 (59%), Gaps = 42/722 (5%)
Query: 23 YSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAPHLLDVDADSG 82
YSV EE G+ +G+I +D L+P AERG R++ L ++ SG
Sbjct: 33 YSVSEETDKGSFVGDIAKDLGLEPR-ELAERG---------VRIISRGRTQLFALNQRSG 82
Query: 83 LLYTKQRIDRESLCRHNAKCQLSLEVFANDK-EICMIKVEIQDINDNAPSFSSDQIEMDI 141
L T RIDRE +C +A+C ++ + DK + I VEI DINDN P F +++I + I
Sbjct: 83 SLVTAGRIDREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPRFLTEEINVKI 142
Query: 142 SENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFPELVIQKAL 201
EN APG RFPL+ A DPD G N L++Y L+ + H F L V+S D TK+PELV+++ L
Sbjct: 143 MENTAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRH--FSLAVQSGDDETKYPELVLERVL 200
Query: 202 DREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELPENAPLGTV 261
DRE++ H LVLTA DGG+PPRS+T I V V+D ND++PVF P Y V +PEN P+GT
Sbjct: 201 DREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTR 260
Query: 262 VIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEENGMLEIDV 321
++ ++A D DEG NGEV YSF P ++ ++F ++ TG I LDYEE E++V
Sbjct: 261 LLTVHAIDLDEGVNGEVTYSFRKITP-KLPKMFHLNSLTGEISTLEGLDYEETAFYEMEV 319
Query: 322 QARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPGTVIALVRVTDRDS 381
QA+D GP + KV + ++D NDNAP + S+ ++ E P GTVIAL + DRDS
Sbjct: 320 QAQD-GPGSL-TKAKVLITVLDVNDNAPEVTMTSL-SSSIPEDTPLGTVIALFYLQDRDS 376
Query: 382 GKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRPLDRETQDEYNVT 441
GKNG++ C + ++PFKLE++ DN+Y +VT + LDRET YN+T
Sbjct: 377 GKNGEVTCTI---------------PENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNIT 421
Query: 442 IVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGEYLGSVLAQDPDL 501
+ A DGG+PPL+ +++ D NDNPP F Y + + ENN G + V AQD D
Sbjct: 422 LKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDS 481
Query: 502 GQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKVLAKDSGAPA 561
N ++YS+ I + +YVS+N G +YAL+SF++EQ + + +V A DSG P
Sbjct: 482 EDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPP 541
Query: 562 HLESNATVRVTVLDVNDNAPVIVLPTLQND--TAELQVPRNAGLGYLVSTVRALDSDFGE 619
L SN ++ + VLD NDN P I+ P L D T PR+A GYLV+ V A+D D G+
Sbjct: 542 -LSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQ 600
Query: 620 SGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTDHGKPTLSAVAKL 679
+ L+Y ++ ++ LF + +GE+RT + LVV V DHG+P LSA L
Sbjct: 601 NAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTL 660
Query: 680 IIRSVSGSLPE-----GVPRVNGEQHHWDMSLPLIVTLSTISIILLA-AMITIAVKCKRE 733
+ +V+ S+PE G + +++D++L L+V ++T+S + LA ++ +A++ +R
Sbjct: 661 TV-AVADSIPEVLADLGSLEPSDGPYNYDLTLYLVVAVATVSCVFLAFVLVLLALRLRRW 719
Query: 734 NK 735
+K
Sbjct: 720 HK 721
Score = 93.2 bits (230), Expect = 1e-18
Identities = 93/342 (27%), Positives = 150/342 (43%), Gaps = 30/342 (8%)
Query: 13 APALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAP 72
AP +T+ +L+ S+PE+ GTVI R G++ + + EN P
Sbjct: 344 APEVTMTSLSSSIPEDTPLGTVIALFYLQDR-----------DSGKNGEVTCTIPEN-LP 391
Query: 73 HLLDVDADSGL-LYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKVEIQDINDNAPS 131
L+ D+ L T + +DRE+L +N + + I +++ D NDN P+
Sbjct: 392 FKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPT 451
Query: 132 FSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSR-GDGT 190
F + I+EN G L +A D D+ +N TY L D + G V S +
Sbjct: 452 FPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAEDT--IQGAPVSSYVSINS 509
Query: 191 KFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLV 250
L ++ D EQ L +TA D G+PP S+ + +++ V+D NDN P P+
Sbjct: 510 DTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPT 569
Query: 251 E-------LPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRE--LFSIDPKTG 301
+ P +A G +V + A D D G N ++ SY+ + E LF++ TG
Sbjct: 570 DGSTGMELAPRSAEPGYLVTKVVAVDKDSGQN-----AWLSYLLLKASEPGLFAVGLYTG 624
Query: 302 LIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLID 343
+R L + + V +D G P+ A +TV + D
Sbjct: 625 EVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 666
>gi|14270508 protocadherin gamma subfamily B, 7 isoform 2 precursor
[Homo sapiens]
Length = 808
Score = 499 bits (1284), Expect = e-141
Identities = 296/720 (41%), Positives = 420/720 (58%), Gaps = 43/720 (5%)
Query: 21 LNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAPHL-LDVDA 79
+ YS+PEE G+V+GN+ +D L S R L SA L VDA
Sbjct: 33 IRYSIPEELAKGSVVGNLAKDLGLSV-------------LDVSARELRVSAEKLHFSVDA 79
Query: 80 DSGLLYTKQRIDRESLCRHNAKCQLSLE-VFANDKEICMIKVEIQDINDNAPSFSSDQIE 138
SG L K RIDRE +C+ +C+L LE V N I + V I+D+ND+AP F D+I
Sbjct: 80 QSGDLLVKDRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKDEIN 139
Query: 139 MDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFPELVIQ 198
++ISE+ + G L SA DPD N L Y L+ +++ F L K DG K+PELV+Q
Sbjct: 140 LEISESVSLGMGTILESAEDPDISMNSLSKYQLSPNEY--FSLVEKDNPDGGKYPELVLQ 197
Query: 199 KALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELPENAPL 258
K LDRE Q+ H LVLTALDGG+PPRS T QI + VID+NDN PVF Y V L E+ P
Sbjct: 198 KTLDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVSLREDVPP 257
Query: 259 GTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEENGMLE 318
GT ++ + ATD DEG N E+ YSF V D+ + +FS+D TG I + LD+EE
Sbjct: 258 GTSILRVKATDQDEGINSEITYSFFG-VADKAQHVFSLDYTTGNILTQQPLDFEEVERYT 316
Query: 319 IDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPGTVIALVRVTD 378
I+++A+D G + CKV V+++D NDN+P I S+ + E +PPG V+AL + D
Sbjct: 317 INIEAKDRGS--LSTRCKVIVEVVDENDNSPEIIITSLSD-QIMEDSPPGVVVALFKTRD 373
Query: 379 RDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRPLDRETQDEY 438
+DSG+NG+++C + G VPFK+ + +N+Y +VTD LDRE EY
Sbjct: 374 QDSGENGEVRCSLSRG---------------VPFKIHSSSNNYYKLVTDEALDREQTPEY 418
Query: 439 NVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGEYLGSVLAQD 498
NVTI A D G PPL+S+K+ + I D NDN P F + Y++ V ENN PG + V A D
Sbjct: 419 NVTIAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASIAQVSASD 478
Query: 499 PDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKVLAKDSG 558
PD G NG VSYS++ S + ++ +YVSV+ +G ++A R+F+ EQ + FE + A+D G
Sbjct: 479 PDFGLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQG 538
Query: 559 APAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAEL--QVPRNAGLGYLVSTVRALDSD 616
+PA L +N ++RV V D NDNAP ++ P L D + L VPR A GYLV+ V A+D+D
Sbjct: 539 SPA-LSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDTVPRAAQPGYLVTKVVAVDAD 597
Query: 617 FGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTDHGKPTLSAV 676
G + L+Y +V ++ LF + +GE+R + + + L+V V D G+P LSA
Sbjct: 598 SGHNAWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDSVRQRLLVAVRDGGQPPLSAT 657
Query: 677 AKL---IIRSVSGSLPEGVPRVNGEQHHWDMSLPLIVTLSTISII-LLAAMITIAVKCKR 732
A L S+ LP+ +M L+V L+ IS++ LLA ++ IA++ ++
Sbjct: 658 ATLHLVFADSLQEVLPDFSDHPTPSDSQAEMQFYLVVALALISVLFLLAVILAIALRLRQ 717
>gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precursor
[Homo sapiens]
Length = 929
Score = 499 bits (1284), Expect = e-141
Identities = 296/720 (41%), Positives = 420/720 (58%), Gaps = 43/720 (5%)
Query: 21 LNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAPHL-LDVDA 79
+ YS+PEE G+V+GN+ +D L S R L SA L VDA
Sbjct: 33 IRYSIPEELAKGSVVGNLAKDLGLSV-------------LDVSARELRVSAEKLHFSVDA 79
Query: 80 DSGLLYTKQRIDRESLCRHNAKCQLSLE-VFANDKEICMIKVEIQDINDNAPSFSSDQIE 138
SG L K RIDRE +C+ +C+L LE V N I + V I+D+ND+AP F D+I
Sbjct: 80 QSGDLLVKDRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKDEIN 139
Query: 139 MDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFPELVIQ 198
++ISE+ + G L SA DPD N L Y L+ +++ F L K DG K+PELV+Q
Sbjct: 140 LEISESVSLGMGTILESAEDPDISMNSLSKYQLSPNEY--FSLVEKDNPDGGKYPELVLQ 197
Query: 199 KALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELPENAPL 258
K LDRE Q+ H LVLTALDGG+PPRS T QI + VID+NDN PVF Y V L E+ P
Sbjct: 198 KTLDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVSLREDVPP 257
Query: 259 GTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEENGMLE 318
GT ++ + ATD DEG N E+ YSF V D+ + +FS+D TG I + LD+EE
Sbjct: 258 GTSILRVKATDQDEGINSEITYSFFG-VADKAQHVFSLDYTTGNILTQQPLDFEEVERYT 316
Query: 319 IDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPGTVIALVRVTD 378
I+++A+D G + CKV V+++D NDN+P I S+ + E +PPG V+AL + D
Sbjct: 317 INIEAKDRGS--LSTRCKVIVEVVDENDNSPEIIITSLSD-QIMEDSPPGVVVALFKTRD 373
Query: 379 RDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRPLDRETQDEY 438
+DSG+NG+++C + G VPFK+ + +N+Y +VTD LDRE EY
Sbjct: 374 QDSGENGEVRCSLSRG---------------VPFKIHSSSNNYYKLVTDEALDREQTPEY 418
Query: 439 NVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGEYLGSVLAQD 498
NVTI A D G PPL+S+K+ + I D NDN P F + Y++ V ENN PG + V A D
Sbjct: 419 NVTIAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASIAQVSASD 478
Query: 499 PDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKVLAKDSG 558
PD G NG VSYS++ S + ++ +YVSV+ +G ++A R+F+ EQ + FE + A+D G
Sbjct: 479 PDFGLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQG 538
Query: 559 APAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAEL--QVPRNAGLGYLVSTVRALDSD 616
+PA L +N ++RV V D NDNAP ++ P L D + L VPR A GYLV+ V A+D+D
Sbjct: 539 SPA-LSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDTVPRAAQPGYLVTKVVAVDAD 597
Query: 617 FGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTDHGKPTLSAV 676
G + L+Y +V ++ LF + +GE+R + + + L+V V D G+P LSA
Sbjct: 598 SGHNAWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDSVRQRLLVAVRDGGQPPLSAT 657
Query: 677 AKL---IIRSVSGSLPEGVPRVNGEQHHWDMSLPLIVTLSTISII-LLAAMITIAVKCKR 732
A L S+ LP+ +M L+V L+ IS++ LLA ++ IA++ ++
Sbjct: 658 ATLHLVFADSLQEVLPDFSDHPTPSDSQAEMQFYLVVALALISVLFLLAVILAIALRLRQ 717
>gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 495 bits (1274), Expect = e-139
Identities = 290/734 (39%), Positives = 429/734 (58%), Gaps = 44/734 (5%)
Query: 11 LWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENS 70
LW A + YS+PEE G+ +GNI +D L+P AE G R++
Sbjct: 23 LWGAAAA--QIRYSIPEELEKGSFVGNIVKDLGLEPQ-ELAEHG---------VRIVSRG 70
Query: 71 APHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDK-EICMIKVEIQDINDNA 129
L ++ +G L T RIDRE LC + +C +S + DK + ++VEI DINDN
Sbjct: 71 RMQLFSLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNT 130
Query: 130 PSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDG 189
P F +++E+ I ENAAP +RFPL +DPD G N L+ + L+ + H F +DV+S G
Sbjct: 131 PRFLKEELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSH--FSVDVQSEAHG 188
Query: 190 TKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYL 249
K+PELV++ LDRE + + LVLTA+DGG+P RS+ QI V V+D NDN+P+F P Y
Sbjct: 189 PKYPELVLEGTLDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYR 248
Query: 250 VELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNL 309
V +PEN P+GT V+ + ATD DEG +GEV YSF + +++ ++F ++ TG I NL
Sbjct: 249 VSVPENLPVGTPVLAVTATDQDEGVHGEVTYSFVK-ITEKISQIFCLNVLTGEISTSANL 307
Query: 310 DYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPGT 369
DYE++ E+ V+ARD GP + KV + ++D NDN P + V+ ++E+APPGT
Sbjct: 308 DYEDSSFYELGVEARD-GPG-LRDRAKVLITILDVNDNVPEV-VVTSGSRTIAESAPPGT 364
Query: 370 VIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRP 429
VIAL +V DRDSG NG + C + S+PF+LE++ N+Y +VT+
Sbjct: 365 VIALFQVFDRDSGLNGLVTCSI---------------PRSLPFELEKSVGNYYRLVTNAA 409
Query: 430 LDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGE 489
LDRE YN+T+ A D G+PPL++ ++ + D NDNPP F Y + V ENN G
Sbjct: 410 LDREEVFLYNITVTATDKGTPPLSTETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGA 469
Query: 490 YLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFE 549
+ SV A DPD+ QN VSYS+ + + +YVS+N G +YALRSF++EQ + +
Sbjct: 470 SIFSVNALDPDVDQNAQVSYSLAEDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQ 529
Query: 550 FKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQND--TAELQVPRNAGLGYLV 607
V A DSG P L SN ++ + VLD NDNAP I+ P L D T PR+A GYLV
Sbjct: 530 LWVTASDSGDPP-LSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLV 588
Query: 608 STVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTD 667
+ V A+D D G++ L+Y ++ ++ LF + +GE+RT + LVV V D
Sbjct: 589 TKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQD 648
Query: 668 HGKPTLSAVAKLIIRSVSGSLPE-----GVPRVNGEQHHWDMSLPLIVTLSTISIILLA- 721
HG+P LSA L + +V+ +P+ G + + + D++L L+V ++ +S + LA
Sbjct: 649 HGQPPLSATVTLTV-AVADRIPDILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAF 707
Query: 722 AMITIAVKCKRENK 735
++ +A++ +R +K
Sbjct: 708 VIVLLALRLQRWHK 721
>gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precursor
[Homo sapiens]
Length = 818
Score = 495 bits (1274), Expect = e-139
Identities = 290/734 (39%), Positives = 429/734 (58%), Gaps = 44/734 (5%)
Query: 11 LWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENS 70
LW A + YS+PEE G+ +GNI +D L+P AE G R++
Sbjct: 23 LWGAAAA--QIRYSIPEELEKGSFVGNIVKDLGLEPQ-ELAEHG---------VRIVSRG 70
Query: 71 APHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDK-EICMIKVEIQDINDNA 129
L ++ +G L T RIDRE LC + +C +S + DK + ++VEI DINDN
Sbjct: 71 RMQLFSLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNT 130
Query: 130 PSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDG 189
P F +++E+ I ENAAP +RFPL +DPD G N L+ + L+ + H F +DV+S G
Sbjct: 131 PRFLKEELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSH--FSVDVQSEAHG 188
Query: 190 TKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYL 249
K+PELV++ LDRE + + LVLTA+DGG+P RS+ QI V V+D NDN+P+F P Y
Sbjct: 189 PKYPELVLEGTLDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYR 248
Query: 250 VELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNL 309
V +PEN P+GT V+ + ATD DEG +GEV YSF + +++ ++F ++ TG I NL
Sbjct: 249 VSVPENLPVGTPVLAVTATDQDEGVHGEVTYSFVK-ITEKISQIFCLNVLTGEISTSANL 307
Query: 310 DYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPGT 369
DYE++ E+ V+ARD GP + KV + ++D NDN P + V+ ++E+APPGT
Sbjct: 308 DYEDSSFYELGVEARD-GPG-LRDRAKVLITILDVNDNVPEV-VVTSGSRTIAESAPPGT 364
Query: 370 VIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRP 429
VIAL +V DRDSG NG + C + S+PF+LE++ N+Y +VT+
Sbjct: 365 VIALFQVFDRDSGLNGLVTCSI---------------PRSLPFELEKSVGNYYRLVTNAA 409
Query: 430 LDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGE 489
LDRE YN+T+ A D G+PPL++ ++ + D NDNPP F Y + V ENN G
Sbjct: 410 LDREEVFLYNITVTATDKGTPPLSTETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGA 469
Query: 490 YLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFE 549
+ SV A DPD+ QN VSYS+ + + +YVS+N G +YALRSF++EQ + +
Sbjct: 470 SIFSVNALDPDVDQNAQVSYSLAEDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQ 529
Query: 550 FKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQND--TAELQVPRNAGLGYLV 607
V A DSG P L SN ++ + VLD NDNAP I+ P L D T PR+A GYLV
Sbjct: 530 LWVTASDSGDPP-LSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLV 588
Query: 608 STVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTD 667
+ V A+D D G++ L+Y ++ ++ LF + +GE+RT + LVV V D
Sbjct: 589 TKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQD 648
Query: 668 HGKPTLSAVAKLIIRSVSGSLPE-----GVPRVNGEQHHWDMSLPLIVTLSTISIILLA- 721
HG+P LSA L + +V+ +P+ G + + + D++L L+V ++ +S + LA
Sbjct: 649 HGQPPLSATVTLTV-AVADRIPDILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAF 707
Query: 722 AMITIAVKCKRENK 735
++ +A++ +R +K
Sbjct: 708 VIVLLALRLQRWHK 721
>gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precursor
[Homo sapiens]
Length = 878
Score = 490 bits (1261), Expect = e-138
Identities = 304/829 (36%), Positives = 457/829 (55%), Gaps = 64/829 (7%)
Query: 3 LSICCCFLLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSG 62
LS+CC W L YSV EE GT++GN+ +D L+ + R G ++G
Sbjct: 19 LSLCCWG--WVSG----QLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENG 72
Query: 63 SYRVLENSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDK-EICMIKVE 121
Y + SG L Q+IDRESLC + C L ++V E+ ++VE
Sbjct: 73 RY----------FSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVE 122
Query: 122 IQDINDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGL 181
I D+NDN+PSF++ + EM ISE+AA G RFPL SA DPD G N + Y L+ + H F L
Sbjct: 123 ILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSH--FSL 180
Query: 182 DVKSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSP 241
+VK+ DG FPELV+++ LDRE Q H LVLTA+DGG P RS T I+V V+D NDN+P
Sbjct: 181 NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP 240
Query: 242 VFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTG 301
F++ V +PENAP+GT+++ LNATD DEG NG++ YSF + + VR LF +DP +G
Sbjct: 241 TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG 300
Query: 302 LIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGAL 361
I V G +D+EE+ EI +ARD G + HC + V + D NDNAP + S+ L
Sbjct: 301 AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL 360
Query: 362 SEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNF 421
E+ P GTV+ L V DRDSG+NG++ + +PF+++ + +N
Sbjct: 361 -ESTPVGTVVGLFNVRDRDSGRNGEVSLDI---------------SPDLPFQIKPS-ENH 403
Query: 422 YTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQV 481
Y+++T +PLDRE Y + ++A D GSP L+ + + I D NDN PRF + LY +
Sbjct: 404 YSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYI 463
Query: 482 HENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFN 541
EN PG L +V A DPD G N ++YSI+ + + ++V VNP +G I+A R+F+
Sbjct: 464 LENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFD 523
Query: 542 FEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQ-NDTAELQVPRN 600
+E + + V +DSG+P L +N ++ V VLD NDNAP ++ P +A ++PR+
Sbjct: 524 YELLQMLQIVVGVRDSGSPP-LHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRS 582
Query: 601 AGLGYLVSTVRALDSDFGESGRLTYEIV-DGNDDHLFEIDPSSGEIRTLHPFWEDVTPVV 659
A G LV+ V A+D+D G + L+Y ++ LF + +GE+RT ED +
Sbjct: 583 APPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQ 642
Query: 660 ELVVKVTDHGKPTLSAVAKLIIRSVSGSLPEGVPRVNGEQHH----WDMSLPLIVTLSTI 715
++VV V D+G P+LS+ A +++ + PE +P+ + H D++L LIV L+T+
Sbjct: 643 QVVVLVRDNGDPSLSSTATVLL-VLEDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATV 701
Query: 716 SIILLAAMITIAVKCKRENKEIRTYNCRIAEYSHPQLGGGKGKKKKINKNDIMLVQS--- 772
S++ L ++ KC + N + GGG+ +++ + + QS
Sbjct: 702 SLLSLVTFTFLSAKCLQGNAD-------------GDGGGGQCCRRQDSPSPDFYKQSSPN 748
Query: 773 -EVEERNAMNVMNVVSSPSLATSPMYFDYQTRLPLSSPRSEVMYLKPAS 820
+V + M V P T Y+T +S S+ +L+P S
Sbjct: 749 LQVSSDGTLKYMEVTLRP---TDSQSHCYRTCFSPASDGSDFTFLRPLS 794
>gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precursor
[Homo sapiens]
Length = 944
Score = 490 bits (1261), Expect = e-138
Identities = 304/829 (36%), Positives = 457/829 (55%), Gaps = 64/829 (7%)
Query: 3 LSICCCFLLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSG 62
LS+CC W L YSV EE GT++GN+ +D L+ + R G ++G
Sbjct: 19 LSLCCWG--WVSG----QLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENG 72
Query: 63 SYRVLENSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDK-EICMIKVE 121
Y + SG L Q+IDRESLC + C L ++V E+ ++VE
Sbjct: 73 RY----------FSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVE 122
Query: 122 IQDINDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGL 181
I D+NDN+PSF++ + EM ISE+AA G RFPL SA DPD G N + Y L+ + H F L
Sbjct: 123 ILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSH--FSL 180
Query: 182 DVKSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSP 241
+VK+ DG FPELV+++ LDRE Q H LVLTA+DGG P RS T I+V V+D NDN+P
Sbjct: 181 NVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP 240
Query: 242 VFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTG 301
F++ V +PENAP+GT+++ LNATD DEG NG++ YSF + + VR LF +DP +G
Sbjct: 241 TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG 300
Query: 302 LIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGAL 361
I V G +D+EE+ EI +ARD G + HC + V + D NDNAP + S+ L
Sbjct: 301 AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL 360
Query: 362 SEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNF 421
E+ P GTV+ L V DRDSG+NG++ + +PF+++ + +N
Sbjct: 361 -ESTPVGTVVGLFNVRDRDSGRNGEVSLDI---------------SPDLPFQIKPS-ENH 403
Query: 422 YTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQV 481
Y+++T +PLDRE Y + ++A D GSP L+ + + I D NDN PRF + LY +
Sbjct: 404 YSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYI 463
Query: 482 HENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFN 541
EN PG L +V A DPD G N ++YSI+ + + ++V VNP +G I+A R+F+
Sbjct: 464 LENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFD 523
Query: 542 FEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQ-NDTAELQVPRN 600
+E + + V +DSG+P L +N ++ V VLD NDNAP ++ P +A ++PR+
Sbjct: 524 YELLQMLQIVVGVRDSGSPP-LHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRS 582
Query: 601 AGLGYLVSTVRALDSDFGESGRLTYEIV-DGNDDHLFEIDPSSGEIRTLHPFWEDVTPVV 659
A G LV+ V A+D+D G + L+Y ++ LF + +GE+RT ED +
Sbjct: 583 APPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQ 642
Query: 660 ELVVKVTDHGKPTLSAVAKLIIRSVSGSLPEGVPRVNGEQHH----WDMSLPLIVTLSTI 715
++VV V D+G P+LS+ A +++ + PE +P+ + H D++L LIV L+T+
Sbjct: 643 QVVVLVRDNGDPSLSSTATVLL-VLEDEDPEEMPKSSDFLIHPPERSDLTLYLIVALATV 701
Query: 716 SIILLAAMITIAVKCKRENKEIRTYNCRIAEYSHPQLGGGKGKKKKINKNDIMLVQS--- 772
S++ L ++ KC + N + GGG+ +++ + + QS
Sbjct: 702 SLLSLVTFTFLSAKCLQGNAD-------------GDGGGGQCCRRQDSPSPDFYKQSSPN 748
Query: 773 -EVEERNAMNVMNVVSSPSLATSPMYFDYQTRLPLSSPRSEVMYLKPAS 820
+V + M V P T Y+T +S S+ +L+P S
Sbjct: 749 LQVSSDGTLKYMEVTLRP---TDSQSHCYRTCFSPASDGSDFTFLRPLS 794
>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
Length = 936
Score = 489 bits (1259), Expect = e-138
Identities = 287/728 (39%), Positives = 426/728 (58%), Gaps = 41/728 (5%)
Query: 21 LNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAPHLLDVDAD 80
L+YS+PEE GT +G I +D GL AE +RV LL+V+
Sbjct: 30 LHYSIPEEAKHGTFVGRIAQDL----GLELAEL------VPRLFRVASKGRGDLLEVNLQ 79
Query: 81 SGLLYTKQRIDRESLCRHNAKCQLSLEVFANDK-EICMIKVEIQDINDNAPSFSSDQIEM 139
+G+L+ RIDRE LCR A+C + LEV + ++ ++V ++DINDN P FS + +
Sbjct: 80 NGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNPPRFSRQEQRL 139
Query: 140 DISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFPELVIQK 199
I E+ P +RFPL A D D G N Y L +++ F LDVK+ + T F ELV++K
Sbjct: 140 FILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEY--FDLDVKTNEEETNFLELVLRK 197
Query: 200 ALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELPENAPLG 259
+LDRE+ H L++ A DGG+P + TVQ+ + V+D+NDN+P F+ Y V L ENAP G
Sbjct: 198 SLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRLLENAPSG 257
Query: 260 TVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEENGMLEI 319
T+VI LNA+DADEG N E++Y FS+ V D V+ F I+ TG I+V G LDYE+ EI
Sbjct: 258 TLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYEDYNSYEI 317
Query: 320 DVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPGTVIALVRVTDR 379
++ A D P+ HCKV VKL+D NDN P + ++ + E AP TVIAL+ V+DR
Sbjct: 318 NIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFL-PVKEDAPLSTVIALISVSDR 376
Query: 380 DSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRPLDRETQDEYN 439
DSG NGQ+ C ++ VPFKL + N+Y++V D LDRE+ Y
Sbjct: 377 DSGANGQVTCSLM---------------PHVPFKLVSTFKNYYSLVLDSALDRESVSVYE 421
Query: 440 VTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGEYLGSVLAQDP 499
+ + ARDGGSP L +T S ++++ D NDN P F + Y + V ENN PG ++ +V A+D
Sbjct: 422 LVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDA 481
Query: 500 DLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKVLAKDSGA 559
D +N VSYS++ +G+ + +YVSV+ +G +YAL+ + E+ + +F+V A+D+G
Sbjct: 482 DAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGV 541
Query: 560 PAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQ--VPRNAGLGYLVSTVRALDSDF 617
P L SN T++V VLD NDNAP +++P + + VPR+ G G++V+ VRA+D D
Sbjct: 542 PP-LGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600
Query: 618 GESGRLTYEI--VDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTDHGKPTLSA 675
G + L+YE+ G+ F + +GEI T E P L+V V DHG+P L+A
Sbjct: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660
Query: 676 VAKLIIRSV-SGSLPEGVPR-----VNGEQHHWDMSLPLIVTLSTI-SIILLAAMITIAV 728
A +++ V SG P+ R V E D+++ LI+ + + S+++L ++ A+
Sbjct: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720
Query: 729 KCKRENKE 736
+C + E
Sbjct: 721 RCSAQPTE 728
>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 816
Score = 489 bits (1259), Expect = e-138
Identities = 287/728 (39%), Positives = 426/728 (58%), Gaps = 41/728 (5%)
Query: 21 LNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAPHLLDVDAD 80
L+YS+PEE GT +G I +D GL AE +RV LL+V+
Sbjct: 30 LHYSIPEEAKHGTFVGRIAQDL----GLELAEL------VPRLFRVASKGRGDLLEVNLQ 79
Query: 81 SGLLYTKQRIDRESLCRHNAKCQLSLEVFANDK-EICMIKVEIQDINDNAPSFSSDQIEM 139
+G+L+ RIDRE LCR A+C + LEV + ++ ++V ++DINDN P FS + +
Sbjct: 80 NGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNPPRFSRQEQRL 139
Query: 140 DISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFPELVIQK 199
I E+ P +RFPL A D D G N Y L +++ F LDVK+ + T F ELV++K
Sbjct: 140 FILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEY--FDLDVKTNEEETNFLELVLRK 197
Query: 200 ALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELPENAPLG 259
+LDRE+ H L++ A DGG+P + TVQ+ + V+D+NDN+P F+ Y V L ENAP G
Sbjct: 198 SLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRLLENAPSG 257
Query: 260 TVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEENGMLEI 319
T+VI LNA+DADEG N E++Y FS+ V D V+ F I+ TG I+V G LDYE+ EI
Sbjct: 258 TLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYEDYNSYEI 317
Query: 320 DVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPGTVIALVRVTDR 379
++ A D P+ HCKV VKL+D NDN P + ++ + E AP TVIAL+ V+DR
Sbjct: 318 NIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFL-PVKEDAPLSTVIALISVSDR 376
Query: 380 DSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRPLDRETQDEYN 439
DSG NGQ+ C ++ VPFKL + N+Y++V D LDRE+ Y
Sbjct: 377 DSGANGQVTCSLM---------------PHVPFKLVSTFKNYYSLVLDSALDRESVSVYE 421
Query: 440 VTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGEYLGSVLAQDP 499
+ + ARDGGSP L +T S ++++ D NDN P F + Y + V ENN PG ++ +V A+D
Sbjct: 422 LVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDA 481
Query: 500 DLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKVLAKDSGA 559
D +N VSYS++ +G+ + +YVSV+ +G +YAL+ + E+ + +F+V A+D+G
Sbjct: 482 DAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGV 541
Query: 560 PAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQ--VPRNAGLGYLVSTVRALDSDF 617
P L SN T++V VLD NDNAP +++P + + VPR+ G G++V+ VRA+D D
Sbjct: 542 PP-LGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600
Query: 618 GESGRLTYEI--VDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTDHGKPTLSA 675
G + L+YE+ G+ F + +GEI T E P L+V V DHG+P L+A
Sbjct: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660
Query: 676 VAKLIIRSV-SGSLPEGVPR-----VNGEQHHWDMSLPLIVTLSTI-SIILLAAMITIAV 728
A +++ V SG P+ R V E D+++ LI+ + + S+++L ++ A+
Sbjct: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720
Query: 729 KCKRENKE 736
+C + E
Sbjct: 721 RCSAQPTE 728
>gi|11128029 protocadherin gamma subfamily B, 6 isoform 1 precursor
[Homo sapiens]
Length = 930
Score = 487 bits (1253), Expect = e-137
Identities = 287/730 (39%), Positives = 424/730 (58%), Gaps = 44/730 (6%)
Query: 11 LWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENS 70
L+ P L+ + + YS+PEE G+V+GN+ +D L S R L S
Sbjct: 24 LFYPTLS-EPIRYSIPEELAKGSVVGNLAKDLGLSV-------------LDVSARKLRVS 69
Query: 71 APHL-LDVDADSGLLYTKQRIDRESLCRHNAKCQLSLE-VFANDKEICMIKVEIQDINDN 128
A L VDA+SG L K RIDRE +C+ +C+L LE V N I + V I+D+ND+
Sbjct: 70 AEKLHFSVDAESGDLLVKNRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDH 129
Query: 129 APSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGD 188
AP F +I ++I E+A+ GTR L A DPD N ++ Y + + + F L V+ D
Sbjct: 130 APQFDKKEIHLEIFESASAGTRLSLDPATDPDININSIKDYKINSNPY--FSLMVRVNSD 187
Query: 189 GTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSY 248
G K+PEL ++K LDRE+Q H+L+LTALDGG+PPRSAT I + V D+NDN PVF Y
Sbjct: 188 GGKYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEY 247
Query: 249 LVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGN 308
+ L EN P G+ V+ + ATD DEG N E+ Y F S + +FS+D KTG+I+ +
Sbjct: 248 RISLSENLPPGSPVLQVTATDQDEGVNAEINYYFRS-TAQSTKHMFSLDEKTGMIKNNQS 306
Query: 309 LDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPG 368
D+E+ ++V+A+D G + CKV ++++D NDN+P I S+ L E +PPG
Sbjct: 307 FDFEDVERYTMEVEAKDGGG--LSTQCKVIIEILDENDNSPEIIITSLSDQIL-ENSPPG 363
Query: 369 TVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDR 428
V+AL + D D G NG+++C + +PFK+ + +N+Y +VTD
Sbjct: 364 MVVALFKTRDLDFGGNGEVRCNI---------------ETDIPFKIYSSSNNYYKLVTDG 408
Query: 429 PLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPG 488
LDRE EYNVTIVA D G PPL+S++S + + D NDN P F + YV+ V ENN PG
Sbjct: 409 ALDREQTPEYNVTIVATDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPG 468
Query: 489 EYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAF 548
+ V A DPDLG NG +SYSI+ S + +++ +YVSV+ +G ++A R+F+ EQ +AF
Sbjct: 469 ASIAQVSASDPDLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAF 528
Query: 549 EFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAEL--QVPRNAGLGYL 606
+ A+D G+P L +N ++RV V D NDNAP ++ P L D + VPR+A GYL
Sbjct: 529 ALTLQARDHGSPT-LSANVSLRVLVGDRNDNAPRVLYPALGPDGSAFFDMVPRSAEPGYL 587
Query: 607 VSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVT 666
V+ V A+D+D G + L+Y ++ ++ LF + +GE+RT + L+V V
Sbjct: 588 VTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVR 647
Query: 667 DHGKPTLSAVAKLII---RSVSGSLPEGVPRVNGEQHHWDMSLPLIVTLSTISII-LLAA 722
D G+P LSA A L + ++ LP+ R ++ L+V L+ IS++ LLA
Sbjct: 648 DGGQPPLSATATLHLVFADNLQEILPDLSDRPVLSDPQAELQFYLVVALALISVLFLLAV 707
Query: 723 MITIAVKCKR 732
++ IA++ +R
Sbjct: 708 ILAIALRLRR 717
>gi|14270502 protocadherin gamma subfamily B, 6 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 487 bits (1253), Expect = e-137
Identities = 287/730 (39%), Positives = 424/730 (58%), Gaps = 44/730 (6%)
Query: 11 LWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENS 70
L+ P L+ + + YS+PEE G+V+GN+ +D L S R L S
Sbjct: 24 LFYPTLS-EPIRYSIPEELAKGSVVGNLAKDLGLSV-------------LDVSARKLRVS 69
Query: 71 APHL-LDVDADSGLLYTKQRIDRESLCRHNAKCQLSLE-VFANDKEICMIKVEIQDINDN 128
A L VDA+SG L K RIDRE +C+ +C+L LE V N I + V I+D+ND+
Sbjct: 70 AEKLHFSVDAESGDLLVKNRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDH 129
Query: 129 APSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGD 188
AP F +I ++I E+A+ GTR L A DPD N ++ Y + + + F L V+ D
Sbjct: 130 APQFDKKEIHLEIFESASAGTRLSLDPATDPDININSIKDYKINSNPY--FSLMVRVNSD 187
Query: 189 GTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSY 248
G K+PEL ++K LDRE+Q H+L+LTALDGG+PPRSAT I + V D+NDN PVF Y
Sbjct: 188 GGKYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEY 247
Query: 249 LVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGN 308
+ L EN P G+ V+ + ATD DEG N E+ Y F S + +FS+D KTG+I+ +
Sbjct: 248 RISLSENLPPGSPVLQVTATDQDEGVNAEINYYFRS-TAQSTKHMFSLDEKTGMIKNNQS 306
Query: 309 LDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPG 368
D+E+ ++V+A+D G + CKV ++++D NDN+P I S+ L E +PPG
Sbjct: 307 FDFEDVERYTMEVEAKDGGG--LSTQCKVIIEILDENDNSPEIIITSLSDQIL-ENSPPG 363
Query: 369 TVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDR 428
V+AL + D D G NG+++C + +PFK+ + +N+Y +VTD
Sbjct: 364 MVVALFKTRDLDFGGNGEVRCNI---------------ETDIPFKIYSSSNNYYKLVTDG 408
Query: 429 PLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPG 488
LDRE EYNVTIVA D G PPL+S++S + + D NDN P F + YV+ V ENN PG
Sbjct: 409 ALDREQTPEYNVTIVATDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPG 468
Query: 489 EYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAF 548
+ V A DPDLG NG +SYSI+ S + +++ +YVSV+ +G ++A R+F+ EQ +AF
Sbjct: 469 ASIAQVSASDPDLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAF 528
Query: 549 EFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAEL--QVPRNAGLGYL 606
+ A+D G+P L +N ++RV V D NDNAP ++ P L D + VPR+A GYL
Sbjct: 529 ALTLQARDHGSPT-LSANVSLRVLVGDRNDNAPRVLYPALGPDGSAFFDMVPRSAEPGYL 587
Query: 607 VSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVT 666
V+ V A+D+D G + L+Y ++ ++ LF + +GE+RT + L+V V
Sbjct: 588 VTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVR 647
Query: 667 DHGKPTLSAVAKLII---RSVSGSLPEGVPRVNGEQHHWDMSLPLIVTLSTISII-LLAA 722
D G+P LSA A L + ++ LP+ R ++ L+V L+ IS++ LLA
Sbjct: 648 DGGQPPLSATATLHLVFADNLQEILPDLSDRPVLSDPQAELQFYLVVALALISVLFLLAV 707
Query: 723 MITIAVKCKR 732
++ IA++ +R
Sbjct: 708 ILAIALRLRR 717
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,340,915
Number of Sequences: 37866
Number of extensions: 2352756
Number of successful extensions: 17893
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 251
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 8543
Number of HSP's gapped (non-prelim): 1799
length of query: 1159
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1046
effective length of database: 13,968,660
effective search space: 14611218360
effective search space used: 14611218360
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.