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Search of human proteins with 94421469
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|94421469 disulfide isomerase [Homo sapiens]
(360 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|94421469 disulfide isomerase [Homo sapiens] 729 0.0
gi|52487191 thioredoxin domain containing 4 (endoplasmic reticul... 51 2e-06
gi|42794771 thioredoxin domain containing 5 isoform 1 precursor ... 45 8e-05
gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo sap... 45 8e-05
gi|4758304 protein disulfide isomerase A4 [Homo sapiens] 45 1e-04
gi|38505222 thioredoxin domain containing 10 [Homo sapiens] 40 0.002
gi|5031973 protein disulfide isomerase A6 [Homo sapiens] 39 0.007
gi|5803121 protein disulfide isomerase A5 [Homo sapiens] 37 0.027
gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s... 37 0.027
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap... 34 0.18
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap... 34 0.18
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi... 34 0.18
gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo sa... 34 0.18
gi|7705726 thioredoxin domain containing 14 isoform 1 [Homo sapi... 34 0.18
gi|54633317 thioredoxin domain containing 11 [Homo sapiens] 34 0.18
gi|4759274 thioredoxin-like 1 [Homo sapiens] 33 0.30
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 33 0.30
gi|94966757 protein disulfide isomerase A2 [Homo sapiens] 33 0.40
gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens] 33 0.40
gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo s... 32 0.68
gi|50592994 thioredoxin [Homo sapiens] 32 1.2
gi|151101292 thioredoxin domain containing 1 [Homo sapiens] 31 1.5
gi|123701922 hypothetical protein LOC285596 [Homo sapiens] 29 7.5
gi|218749848 family with sequence similarity 38, member A [Homo ... 29 7.5
gi|34365783 visual system homeobox 2 [Homo sapiens] 28 9.8
gi|42415492 chromosome 14 open reading frame 106 [Homo sapiens] 28 9.8
>gi|94421469 disulfide isomerase [Homo sapiens]
Length = 360
Score = 729 bits (1882), Expect = 0.0
Identities = 360/360 (100%), Positives = 360/360 (100%)
Query: 1 MVPAAGRRPPRVMRLLGWWQVLLWVLGLPVRGVEVAEESGRLWSEEQPAHPLQVGAVYLG 60
MVPAAGRRPPRVMRLLGWWQVLLWVLGLPVRGVEVAEESGRLWSEEQPAHPLQVGAVYLG
Sbjct: 1 MVPAAGRRPPRVMRLLGWWQVLLWVLGLPVRGVEVAEESGRLWSEEQPAHPLQVGAVYLG 60
Query: 61 EEELLHDPMGQDRAAEEANAVLGLDTQGDHMVMLSVIPGEAEDKVSSEPSGVTCGAGGAE 120
EEELLHDPMGQDRAAEEANAVLGLDTQGDHMVMLSVIPGEAEDKVSSEPSGVTCGAGGAE
Sbjct: 61 EEELLHDPMGQDRAAEEANAVLGLDTQGDHMVMLSVIPGEAEDKVSSEPSGVTCGAGGAE 120
Query: 121 DSRCNVRESLFSLDGAGAHFPDREEEYYTEPEVAESDAAPTEDSNNTESLKSPKVNCEER 180
DSRCNVRESLFSLDGAGAHFPDREEEYYTEPEVAESDAAPTEDSNNTESLKSPKVNCEER
Sbjct: 121 DSRCNVRESLFSLDGAGAHFPDREEEYYTEPEVAESDAAPTEDSNNTESLKSPKVNCEER 180
Query: 181 NITGLENFTLKILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPAL 240
NITGLENFTLKILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPAL
Sbjct: 181 NITGLENFTLKILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPAL 240
Query: 241 HFLALDASQHSSLSTRFGTVAVPNILLFQGAKPMARFNHTDRTLETLKIFIFNQTGIEAK 300
HFLALDASQHSSLSTRFGTVAVPNILLFQGAKPMARFNHTDRTLETLKIFIFNQTGIEAK
Sbjct: 241 HFLALDASQHSSLSTRFGTVAVPNILLFQGAKPMARFNHTDRTLETLKIFIFNQTGIEAK 300
Query: 301 KNVVVTQADQIGPLPSTLIKSVDWLLVFSLFFLISFIMYATIRTESIRWLIPGQEQEHVE 360
KNVVVTQADQIGPLPSTLIKSVDWLLVFSLFFLISFIMYATIRTESIRWLIPGQEQEHVE
Sbjct: 301 KNVVVTQADQIGPLPSTLIKSVDWLLVFSLFFLISFIMYATIRTESIRWLIPGQEQEHVE 360
>gi|52487191 thioredoxin domain containing 4 (endoplasmic reticulum)
[Homo sapiens]
Length = 406
Score = 50.8 bits (120), Expect = 2e-06
Identities = 31/96 (32%), Positives = 44/96 (45%), Gaps = 7/96 (7%)
Query: 206 NGSDCTLVLFYTPWCRFSASLAPHFNS----LPRAFP---ALHFLALDASQHSSLSTRFG 258
N +D LV FY WCRFS L P F + FP + F +D QHS ++ R+
Sbjct: 44 NNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYR 103
Query: 259 TVAVPNILLFQGAKPMARFNHTDRTLETLKIFIFNQ 294
P + LF+ M R R+++ L +I Q
Sbjct: 104 ISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQ 139
>gi|42794771 thioredoxin domain containing 5 isoform 1 precursor
[Homo sapiens]
Length = 432
Score = 45.4 bits (106), Expect = 8e-05
Identities = 36/151 (23%), Positives = 68/151 (45%), Gaps = 16/151 (10%)
Query: 148 YTEPEVAESDAAPTEDSNNTESLKSPKVNCEERNITGLENFTLKILNMSQDLMDFLNPNG 207
Y E ++ ++ TE +E+ P + E G +L ++++ D G
Sbjct: 289 YVESQLQRTETGATETVTPSEA---PVLAAEPEADKGT------VLALTENNFDDTIAEG 339
Query: 208 SDCTLVLFYTPWCRFSASLAPHFNSL-PRAFPAL---HFLALDASQHSSLSTRFGTVAVP 263
T + FY PWC +LAP + L + FP L +D + ++ +++ P
Sbjct: 340 --ITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYP 397
Query: 264 NILLFQGAKPMARFNHTDRTLETLKIFIFNQ 294
+LLF+G K ++ + R L++L F+ +Q
Sbjct: 398 TLLLFRGGKKVSE-HSGGRDLDSLHRFVLSQ 427
Score = 35.4 bits (80), Expect = 0.080
Identities = 22/106 (20%), Positives = 45/106 (42%), Gaps = 7/106 (6%)
Query: 213 VLFYTPWCRFSASLAPHFNSLPRAFPAL-----HFLALDASQHSSLSTRFGTVAVPNILL 267
V+F+ PWC L P +N L + ++ + +D + HS + + G P + L
Sbjct: 82 VMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKL 141
Query: 268 FQGAKPMARFN--HTDRTLETLKIFIFNQTGIEAKKNVVVTQADQI 311
F+ + ++ +TLE + N+ + + V A ++
Sbjct: 142 FKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPEL 187
Score = 33.9 bits (76), Expect = 0.23
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 7/109 (6%)
Query: 213 VLFYTPWCRFSASLAPHFNSLPRAF---PALHFLALDASQHSSLSTRFGTVAVPNILLFQ 269
+ F+ PWC +LAP + L + +D +QH L + P +L F+
Sbjct: 210 IKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFR 269
Query: 270 GAKPMARFNHTDRTLETLKIFIFNQ---TGIEAKKNVVVTQADQIGPLP 315
K + ++ R LE+L+ ++ +Q T A + V ++A + P
Sbjct: 270 DGKKVDQYK-GKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEP 317
>gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo
sapiens]
Length = 324
Score = 45.4 bits (106), Expect = 8e-05
Identities = 36/151 (23%), Positives = 68/151 (45%), Gaps = 16/151 (10%)
Query: 148 YTEPEVAESDAAPTEDSNNTESLKSPKVNCEERNITGLENFTLKILNMSQDLMDFLNPNG 207
Y E ++ ++ TE +E+ P + E G +L ++++ D G
Sbjct: 181 YVESQLQRTETGATETVTPSEA---PVLAAEPEADKGT------VLALTENNFDDTIAEG 231
Query: 208 SDCTLVLFYTPWCRFSASLAPHFNSL-PRAFPAL---HFLALDASQHSSLSTRFGTVAVP 263
T + FY PWC +LAP + L + FP L +D + ++ +++ P
Sbjct: 232 --ITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYP 289
Query: 264 NILLFQGAKPMARFNHTDRTLETLKIFIFNQ 294
+LLF+G K ++ + R L++L F+ +Q
Sbjct: 290 TLLLFRGGKKVSE-HSGGRDLDSLHRFVLSQ 319
Score = 33.9 bits (76), Expect = 0.23
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 7/109 (6%)
Query: 213 VLFYTPWCRFSASLAPHFNSLPRAF---PALHFLALDASQHSSLSTRFGTVAVPNILLFQ 269
+ F+ PWC +LAP + L + +D +QH L + P +L F+
Sbjct: 102 IKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFR 161
Query: 270 GAKPMARFNHTDRTLETLKIFIFNQ---TGIEAKKNVVVTQADQIGPLP 315
K + ++ R LE+L+ ++ +Q T A + V ++A + P
Sbjct: 162 DGKKVDQYK-GKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEP 209
>gi|4758304 protein disulfide isomerase A4 [Homo sapiens]
Length = 645
Score = 45.1 bits (105), Expect = 1e-04
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
Query: 206 NGSDCTLVLFYTPWCRFSASLAPHF----NSLPRAFPALHFLALDASQHSSLSTRFGTVA 261
N +D LV FY PWC LAP + L + P + +DA+ + L+ RF
Sbjct: 192 NDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSG 251
Query: 262 VPNILLFQGAKP 273
P + +F+ +P
Sbjct: 252 YPTLKIFRKGRP 263
Score = 39.7 bits (91), Expect = 0.004
Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 5/85 (5%)
Query: 212 LVLFYTPWCRFSASLAPHFNSLPRAF---PALHFLALDASQHSSLSTRFGTVAVPNILLF 268
L+ FY PWC L P +NSL + + L +DA+ + S R+ P I
Sbjct: 547 LIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTIYFA 606
Query: 269 QGA--KPMARFNHTDRTLETLKIFI 291
K +F DR LE L FI
Sbjct: 607 PSGDKKNPVKFEGGDRDLEHLSKFI 631
Score = 38.9 bits (89), Expect = 0.007
Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 8/118 (6%)
Query: 160 PTEDSNNTES-LKSPKVNCEERNITGLENFTLKILNMSQDLMDFLNPN---GSDCTLVLF 215
P EDS+N E+ ++ + EE + ++ +K N L D N D L+ F
Sbjct: 27 PDEDSSNRENAIEDEEEEEEEDDDEEEDDLEVKEENGVLVLNDANFDNFVADKDTVLLEF 86
Query: 216 YTPWCRFSASLAPHF----NSLPRAFPALHFLALDASQHSSLSTRFGTVAVPNILLFQ 269
Y PWC AP + N L P + +DA+ S L++RF P I + +
Sbjct: 87 YAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILK 144
>gi|38505222 thioredoxin domain containing 10 [Homo sapiens]
Length = 454
Score = 40.4 bits (93), Expect = 0.002
Identities = 36/152 (23%), Positives = 58/152 (38%), Gaps = 20/152 (13%)
Query: 202 FLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPAL----HFLALDASQHSSLSTRF 257
F D LV FY PWC L P +N + ++ +DA+ +SS+++ F
Sbjct: 35 FKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEF 94
Query: 258 GTVAVPNILLFQGAKPMARFNHTDRTLETLKIFIFNQTG--------------IEAKKNV 303
G P I L +G +A RT + + F +G ++ + V
Sbjct: 95 GVRGYPTIKLLKG--DLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRV 152
Query: 304 VVTQADQIGPLPSTLIKSVDWLLVFSLFFLIS 335
PL I + L+V++ FF S
Sbjct: 153 FFVYVGGESPLKEKYIDAASELIVYTYFFSAS 184
>gi|5031973 protein disulfide isomerase A6 [Homo sapiens]
Length = 440
Score = 38.9 bits (89), Expect = 0.007
Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 1/77 (1%)
Query: 212 LVLFYTPWCRFSASLAPHFNSLPRAFP-ALHFLALDASQHSSLSTRFGTVAVPNILLFQG 270
LV FY PWC L P + A + A+DA +H SL ++G P I +F
Sbjct: 47 LVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGS 106
Query: 271 AKPMARFNHTDRTLETL 287
K RT E +
Sbjct: 107 NKNRPEDYQGGRTGEAI 123
Score = 37.7 bits (86), Expect = 0.016
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 6/89 (6%)
Query: 192 ILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSL-----PRAFPALHFLALD 246
++ ++ D D + D +V FY PWC +L P + + + + A+D
Sbjct: 162 VIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVD 221
Query: 247 ASQHSSLSTRFGTVAVPNILLFQ-GAKPM 274
A+ + L++R+G P I +FQ G P+
Sbjct: 222 ATVNQVLASRYGIRGFPTIKIFQKGESPV 250
>gi|5803121 protein disulfide isomerase A5 [Homo sapiens]
Length = 519
Score = 37.0 bits (84), Expect = 0.027
Identities = 18/85 (21%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Query: 212 LVLFYTPWCRFSASLAPHFNSLP---RAFPALHFLALDASQHSSLSTRFGTVAVPNILLF 268
L++FY PWC + PHF R L + + +S+ ++ + P I F
Sbjct: 174 LIMFYAPWCSMCKRMMPHFQKAATQLRGHAVLAGMNVYSSEFENIKEEYSVRGFPTICYF 233
Query: 269 QGAKPMARFNHTDRTLETLKIFIFN 293
+ + + ++++ T E + ++ N
Sbjct: 234 EKGRFLFQYDNYGSTAEDIVEWLKN 258
Score = 36.2 bits (82), Expect = 0.047
Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 13/87 (14%)
Query: 197 QDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALH--------FLALDAS 248
+D F+ + S LV+F+ PWC + P F +A ALH A+DA+
Sbjct: 284 EDFDQFVKEHSS--VLVMFHAPWCGHCKKMKPEFE---KAAEALHGEADSSGVLAAVDAT 338
Query: 249 QHSSLSTRFGTVAVPNILLFQGAKPMA 275
+ +L+ RF P + F+ + A
Sbjct: 339 VNKALAERFHISEFPTLKYFKNGEKYA 365
Score = 34.7 bits (78), Expect = 0.14
Identities = 13/27 (48%), Positives = 16/27 (59%)
Query: 211 TLVLFYTPWCRFSASLAPHFNSLPRAF 237
TLV+FY PWC + PHF + AF
Sbjct: 417 TLVMFYAPWCPHCKKVIPHFTATADAF 443
>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
sapiens]
Length = 508
Score = 37.0 bits (84), Expect = 0.027
Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 4/62 (6%)
Query: 212 LVLFYTPWCRFSASLAPHF----NSLPRAFPALHFLALDASQHSSLSTRFGTVAVPNILL 267
LV FY PWC +LAP + L + +DA++ S L+ ++G P I
Sbjct: 45 LVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKF 104
Query: 268 FQ 269
F+
Sbjct: 105 FR 106
>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 34.3 bits (77), Expect = 0.18
Identities = 28/132 (21%), Positives = 49/132 (37%), Gaps = 3/132 (2%)
Query: 141 PDREEEYYTEPEVA---ESDAAPTEDSNNTESLKSPKVNCEERNITGLENFTLKILNMSQ 197
P +E + PE + D +P T S + + EE + E +K++ +
Sbjct: 331 PPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFPEGDKVKVILSKE 390
Query: 198 DLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALHFLALDASQHSSLSTRF 257
D L G V F WC ++ P F++L + FL +DA +
Sbjct: 391 DFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADNCEEVVREC 450
Query: 258 GTVAVPNILLFQ 269
+ VP ++
Sbjct: 451 AIMCVPTFQFYK 462
>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
sapiens]
Length = 553
Score = 34.3 bits (77), Expect = 0.18
Identities = 28/132 (21%), Positives = 49/132 (37%), Gaps = 3/132 (2%)
Query: 141 PDREEEYYTEPEVA---ESDAAPTEDSNNTESLKSPKVNCEERNITGLENFTLKILNMSQ 197
P +E + PE + D +P T S + + EE + E +K++ +
Sbjct: 398 PPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFPEGDKVKVILSKE 457
Query: 198 DLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALHFLALDASQHSSLSTRF 257
D L G V F WC ++ P F++L + FL +DA +
Sbjct: 458 DFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADNCEEVVREC 517
Query: 258 GTVAVPNILLFQ 269
+ VP ++
Sbjct: 518 AIMCVPTFQFYK 529
>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 34.3 bits (77), Expect = 0.18
Identities = 28/132 (21%), Positives = 49/132 (37%), Gaps = 3/132 (2%)
Query: 141 PDREEEYYTEPEVA---ESDAAPTEDSNNTESLKSPKVNCEERNITGLENFTLKILNMSQ 197
P +E + PE + D +P T S + + EE + E +K++ +
Sbjct: 331 PPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFPEGDKVKVILSKE 390
Query: 198 DLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALHFLALDASQHSSLSTRF 257
D L G V F WC ++ P F++L + FL +DA +
Sbjct: 391 DFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADNCEEVVREC 450
Query: 258 GTVAVPNILLFQ 269
+ VP ++
Sbjct: 451 AIMCVPTFQFYK 462
>gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo
sapiens]
Length = 258
Score = 34.3 bits (77), Expect = 0.18
Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 8/79 (10%)
Query: 212 LVLFYTPWCRFSASLAPHFNSLPRAF--PALHFLALDASQHSSLSTRFG------TVAVP 263
+V F+ W S AP + L + L+F +D +++ +STR+ T +P
Sbjct: 121 IVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLP 180
Query: 264 NILLFQGAKPMARFNHTDR 282
++LFQG K R D+
Sbjct: 181 TLILFQGGKEAMRRPQIDK 199
>gi|7705726 thioredoxin domain containing 14 isoform 1 [Homo
sapiens]
Length = 296
Score = 34.3 bits (77), Expect = 0.18
Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 8/79 (10%)
Query: 212 LVLFYTPWCRFSASLAPHFNSLPRAF--PALHFLALDASQHSSLSTRFG------TVAVP 263
+V F+ W S AP + L + L+F +D +++ +STR+ T +P
Sbjct: 159 IVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLP 218
Query: 264 NILLFQGAKPMARFNHTDR 282
++LFQG K R D+
Sbjct: 219 TLILFQGGKEAMRRPQIDK 237
>gi|54633317 thioredoxin domain containing 11 [Homo sapiens]
Length = 958
Score = 34.3 bits (77), Expect = 0.18
Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 3/59 (5%)
Query: 212 LVLFYTPWCRFSASLAPHFNSLPRAFPALHFLA--LDASQHSSLSTRFGTVAVPNILLF 268
L+L+Y PWC F SL F L R P F +D SQ + L F +P +L F
Sbjct: 684 LLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVARIDVSQ-NDLPWEFMVDRLPTVLFF 741
>gi|4759274 thioredoxin-like 1 [Homo sapiens]
Length = 289
Score = 33.5 bits (75), Expect = 0.30
Identities = 22/92 (23%), Positives = 36/92 (39%)
Query: 190 LKILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALHFLALDASQ 249
+K + D L+ GS +V F C +AP F+S+ +P FL +D Q
Sbjct: 4 VKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQ 63
Query: 250 HSSLSTRFGTVAVPNILLFQGAKPMARFNHTD 281
+ A P L F+ + ++ D
Sbjct: 64 CQGTAATNNISATPTFLFFRNKVRIDQYQGAD 95
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 33.5 bits (75), Expect = 0.30
Identities = 45/160 (28%), Positives = 61/160 (38%), Gaps = 18/160 (11%)
Query: 32 GVEVAEESGRLWSEEQPAHPLQVGAVYLGEEELLHDPMGQDRAAEEANAVLGLDTQGDHM 91
GVE E G E P G E E + P + A E+ V D +G+
Sbjct: 2100 GVEAPEAEGEAQKAEGIEAPETEGEAQ-PESEGIEAPEAEGEAQPESEGVEAQDAEGEAQ 2158
Query: 92 VMLSVIPG-EAEDKVSSEPSGVTC--GAGGAEDSRCNVR------ESLFSLDGAGAHFPD 142
I EAE++ E GV G A+ + E+ L+G A P+
Sbjct: 2159 PESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEA--PE 2216
Query: 143 REEEYYTEPE-----VAESDAAP-TEDSNNTESLKSPKVN 176
EEE EPE AE +A P +E E SP+V+
Sbjct: 2217 AEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVS 2256
Score = 30.4 bits (67), Expect = 2.6
Identities = 29/117 (24%), Positives = 44/117 (37%), Gaps = 4/117 (3%)
Query: 63 ELLHDPMGQDRAAEEANAVLGLDTQGDHMVMLSVIPGEAEDKVSSEPSGVTCGAGGAEDS 122
E + P + A E+ V + +GD E+ED + E G +ED
Sbjct: 1833 EGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEA--QPESEDV 1890
Query: 123 RCNVRESLFSLDGAGAHFPDREEEYYTEPEVAESDAAPTEDSNNTESLKSPKVNCEE 179
E + GA P+ E+E +PE +A TE + ES + EE
Sbjct: 1891 ETPEAEWEVQPESEGAEAPEAEKE--AQPETESVEALETEGEDEPESEGAEAQEAEE 1945
>gi|94966757 protein disulfide isomerase A2 [Homo sapiens]
Length = 525
Score = 33.1 bits (74), Expect = 0.40
Identities = 17/62 (27%), Positives = 25/62 (40%), Gaps = 4/62 (6%)
Query: 212 LVLFYTPWCRFSASLAPHFNSLPRAFPA----LHFLALDASQHSSLSTRFGTVAVPNILL 267
LV FY PWC +LAP ++ A + +D L+ FG P +
Sbjct: 63 LVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKF 122
Query: 268 FQ 269
F+
Sbjct: 123 FR 124
>gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]
Length = 505
Score = 33.1 bits (74), Expect = 0.40
Identities = 19/86 (22%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 212 LVLFYTPWCRFSASLAPHFNSLPRAFPALHFLA-LDASQHSSLSTRFGTVAVPNILLFQG 270
LV F+ PWC LAP + + + LA +D + +++ ++G P + +F+
Sbjct: 49 LVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRD 108
Query: 271 AKPMARFNHTDRTLETLKIFIFNQTG 296
+ ++ RT + + + Q G
Sbjct: 109 GEEAGAYD-GPRTADGIVSHLKKQAG 133
Score = 30.8 bits (68), Expect = 2.0
Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 15/93 (16%)
Query: 144 EEEYYTEPEVAESDAAPTEDSNNTESLKS---PKVNCEERNITGLENFTLKILNMSQDLM 200
+EE+ + + E D N LKS P+ N + ENF + N ++D+
Sbjct: 339 QEEFSRDGKALERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDV- 397
Query: 201 DFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSL 233
L+ FY PWC +L P + L
Sbjct: 398 -----------LIEFYAPWCGHCKNLEPKYKEL 419
>gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo
sapiens]
Length = 793
Score = 32.3 bits (72), Expect = 0.68
Identities = 24/124 (19%), Positives = 47/124 (37%), Gaps = 5/124 (4%)
Query: 206 NGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPA-LHFLALDASQHSSLSTRFGTVAVPN 264
N + V FY+P C LAP + + L A++ L G + P+
Sbjct: 144 NSGELWFVNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCGDDRMLCRMKGVNSYPS 203
Query: 265 ILLFQGAKPMARFNHTDRTLETLKIFIFNQTGIEAKKNVVVTQADQIGPLPSTLIKSVDW 324
+ +F+ ++ H DR+ E+L F + + + + + + + W
Sbjct: 204 LFIFRSGMAPVKY-HGDRSKESLVSFAMQHVRSTVTE---LWTGNFVNSIQTAFAAGIGW 259
Query: 325 LLVF 328
L+ F
Sbjct: 260 LITF 263
Score = 30.0 bits (66), Expect = 3.4
Identities = 18/70 (25%), Positives = 28/70 (40%), Gaps = 1/70 (1%)
Query: 212 LVLFYTPWCRFSASLAPHFNSLPRAFPAL-HFLALDASQHSSLSTRFGTVAVPNILLFQG 270
+V FY+PWC L P + + R L + ++D Q+ S + P I F
Sbjct: 580 MVDFYSPWCHPCQVLMPEWKRMARTLTGLINVGSIDCQQYHSFCAQENVQRYPEIRFFPP 639
Query: 271 AKPMARFNHT 280
A H+
Sbjct: 640 KSNKAYHYHS 649
>gi|50592994 thioredoxin [Homo sapiens]
Length = 105
Score = 31.6 bits (70), Expect = 1.2
Identities = 17/93 (18%), Positives = 37/93 (39%)
Query: 190 LKILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALHFLALDASQ 249
+K + + L+ G +V F WC + P F+SL + + FL +D
Sbjct: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
Query: 250 HSSLSTRFGTVAVPNILLFQGAKPMARFNHTDR 282
+++ +P F+ + + F+ ++
Sbjct: 62 CQDVASECEVKCMPTFQFFKKGQKVGEFSGANK 94
>gi|151101292 thioredoxin domain containing 1 [Homo sapiens]
Length = 280
Score = 31.2 bits (69), Expect = 1.5
Identities = 17/56 (30%), Positives = 26/56 (46%), Gaps = 2/56 (3%)
Query: 212 LVLFYTPWCRFSASLAPHFNSLPRAFPAL--HFLALDASQHSSLSTRFGTVAVPNI 265
++ FY PWC +L P + S L + +D ++ LS RF A+P I
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVTEQPGLSGRFIITALPTI 103
>gi|123701922 hypothetical protein LOC285596 [Homo sapiens]
Length = 310
Score = 28.9 bits (63), Expect = 7.5
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 21/96 (21%)
Query: 52 LQVGAVYLGEEELLHDPMGQDRAAEEANAVLGLDTQGDHMVMLSVIPGEAEDKVSSEPSG 111
LQ + Y GEEE DP EE LG+ +GD + +PG+ VS E +G
Sbjct: 151 LQELSSYNGEEE---DP-------EEVKTSLGVPQRGDLEDLEEHVPGQT---VSEEATG 197
Query: 112 V--------TCGAGGAEDSRCNVRESLFSLDGAGAH 139
V T ED +V E S + G H
Sbjct: 198 VHMMQVDPATLAKSDLEDLEEHVPEQTVSEEATGVH 233
>gi|218749848 family with sequence similarity 38, member A [Homo
sapiens]
Length = 2090
Score = 28.9 bits (63), Expect = 7.5
Identities = 41/156 (26%), Positives = 62/156 (39%), Gaps = 15/156 (9%)
Query: 4 AAGRRPPRVMRLLGWWQVLLWVLGLPVRGVEVAEESGRLWSEEQPAHPLQVGAVYLGEEE 63
AA R V R+L Q LW+LG + +E R W +E H + V E
Sbjct: 1065 AAAGRSHVVQRVLSTAQ-FLWMLGQAL-----VDELTR-WLQEFTRHHGTMSDVLRAERY 1117
Query: 64 LLHDPMGQDRAAEEANAVLGLDTQGDHMVMLSVIPGEAEDKVSSEPSGVTCGAGGAEDSR 123
LL + Q +Q + + +PG E + PS V+ G G AE+
Sbjct: 1118 LLTQELLQGGEVHRGVLDQLYTSQAE-----ATLPGPTE--APNAPSTVSSGLG-AEEPL 1169
Query: 124 CNVRESLFSLDGAGAHFPDREEEYYTEPEVAESDAA 159
++ + + S G H EE T+P E+ A+
Sbjct: 1170 SSMTDDMGSPLSTGYHTRSGSEEAVTDPGEREAGAS 1205
>gi|34365783 visual system homeobox 2 [Homo sapiens]
Length = 361
Score = 28.5 bits (62), Expect = 9.8
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 12/99 (12%)
Query: 24 WVLGLPVRGVEVAEESGRLWSEEQPAHPL----------QVGAVYLGEEELLHDPMG--Q 71
W+LG+ + +E A ESGR E+ A P + +EEL + + +
Sbjct: 251 WLLGMHKKSLEAAAESGRKPEGERQALPKLDKMEQDERGPDAQAAISQEELRENSIAVLR 310
Query: 72 DRAAEEANAVLGLDTQGDHMVMLSVIPGEAEDKVSSEPS 110
+A E + VLG + D + + P E E P+
Sbjct: 311 AKAQEHSTKVLGTVSGPDSLARSTEKPEEEEAMDEDRPA 349
>gi|42415492 chromosome 14 open reading frame 106 [Homo sapiens]
Length = 1132
Score = 28.5 bits (62), Expect = 9.8
Identities = 17/60 (28%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
Query: 154 AESDAAPTEDSNNTESLK-SPKVNCEERNITGLENFTLKILNMSQDLMDFLNPNGSDCTL 212
A P E SNN L K+ C++ L N T ++ ++Q+ +FL + TL
Sbjct: 182 ASVQGVPLESSNNDIFLPVKQKIQCQQEKKAPLHNLTYELPTLNQEQENFLAVEARNKTL 241
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,384,821
Number of Sequences: 37866
Number of extensions: 655784
Number of successful extensions: 1784
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1750
Number of HSP's gapped (non-prelim): 43
length of query: 360
length of database: 18,247,518
effective HSP length: 103
effective length of query: 257
effective length of database: 14,347,320
effective search space: 3687261240
effective search space used: 3687261240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.