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Search of human proteins with 93277124
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo
sapiens]
(320 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo ... 665 0.0
gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens] 367 e-101
gi|223468663 aldo-keto reductase family 1, member B10 [Homo sapi... 338 3e-93
gi|122937516 aldo-keto reductase family 1, member B10-like [Homo... 334 5e-92
gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens] 278 4e-75
gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens] 273 1e-73
gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens] 272 3e-73
gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens] 270 2e-72
gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens] 270 2e-72
gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens] 264 9e-71
gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens] 249 2e-66
gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens] 249 2e-66
gi|207028673 hypothetical protein LOC100134257 [Homo sapiens] 105 5e-23
gi|4504825 potassium voltage-gated channel, shaker-related subfa... 35 0.089
gi|27436969 potassium voltage-gated channel, shaker-related subf... 35 0.089
gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 30 2.9
gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 30 2.9
gi|4504011 glutamate-cysteine ligase regulatory protein [Homo sa... 29 4.9
gi|169163710 PREDICTED: 5'-nucleotidase domain containing 4 [Hom... 29 6.4
gi|169163021 PREDICTED: 5'-nucleotidase domain containing 4 [Hom... 29 6.4
>gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo
sapiens]
Length = 320
Score = 665 bits (1717), Expect = 0.0
Identities = 320/320 (100%), Positives = 320/320 (100%)
Query: 1 MGDIPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60
MGDIPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR
Sbjct: 1 MGDIPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60
Query: 61 REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE 120
REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE
Sbjct: 61 REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE 120
Query: 121 LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL 180
LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL
Sbjct: 121 LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL 180
Query: 181 LNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCEGVDLIDNPVIKR 240
LNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCEGVDLIDNPVIKR
Sbjct: 181 LNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCEGVDLIDNPVIKR 240
Query: 241 IAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNL 300
IAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNL
Sbjct: 241 IAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNL 300
Query: 301 RLAMFPITKNHKDYPFHIEY 320
RLAMFPITKNHKDYPFHIEY
Sbjct: 301 RLAMFPITKNHKDYPFHIEY 320
>gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens]
Length = 316
Score = 367 bits (941), Expect = e-101
Identities = 180/323 (55%), Positives = 226/323 (69%), Gaps = 25/323 (7%)
Query: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
+P +GL +WK+ PG+VTEAVK AID GYRH DCA+ Y NE EVG I+ K++E V+RE+
Sbjct: 13 MPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREE 72
Query: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
LFI +KLWCT H+K LV+ AC+K+L LKL+YLDLYLIHWP GFKP
Sbjct: 73 LFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK------------ 120
Query: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
+ PLDES V+PSDT+ LDTW AME+LV GLVK IG+SNFNH Q+E +LNK
Sbjct: 121 -------EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNK 173
Query: 184 PGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG------GSCEGVDLIDNPV 237
PGL++KP NQIECHPYLTQ+ LI +CQS+ + VTAY PLG E L+++P
Sbjct: 174 PGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPR 233
Query: 238 IKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLN 297
IK IA +H K+ AQ+LIRF +QRN++VIP S+TP I EN +VFDFEL+ DM +LS N
Sbjct: 234 IKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYN 293
Query: 298 RNLRLAMFPITKNHKDYPFHIEY 320
RN R+ +HKDYPFH E+
Sbjct: 294 RNWRVCALLSCTSHKDYPFHEEF 316
>gi|223468663 aldo-keto reductase family 1, member B10 [Homo
sapiens]
Length = 316
Score = 338 bits (868), Expect = 3e-93
Identities = 177/323 (54%), Positives = 220/323 (68%), Gaps = 25/323 (7%)
Query: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
+P VGL +WK+ GKV EAVK AIDAGYRH DCAY Y NE EVG I+ KI+E AV+RED
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
LFI +KLW T ++ LV A K+LK LKL+YLD+YLIHWP GFK S +L
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK--------SGDDL-- 122
Query: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
P D+ I FLD WEAME+LV GLVK +GVSNF+H Q+E+LLNK
Sbjct: 123 ---------FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNK 173
Query: 184 PGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG------GSCEGVDLIDNPV 237
PGL++KP+TNQ+ECHPYLTQ+ LI +C S+ ++VTAY PLG E L+++P
Sbjct: 174 PGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPK 233
Query: 238 IKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLN 297
IK IA +H K+ AQ+LIRF IQRNVIVIP S+TP+ I ENIQVFDF+L+ +M ILS N
Sbjct: 234 IKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFN 293
Query: 298 RNLRLAMFPITKNHKDYPFHIEY 320
RN R + + +DYPF+ EY
Sbjct: 294 RNWRACNVLQSSHLEDYPFNAEY 316
>gi|122937516 aldo-keto reductase family 1, member B10-like [Homo
sapiens]
Length = 316
Score = 334 bits (857), Expect = 5e-92
Identities = 174/323 (53%), Positives = 216/323 (66%), Gaps = 25/323 (7%)
Query: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
+P VGL +W++ GKV EAVK AIDA YRH DCAYFY N+ EVG I+ KI+E AV RED
Sbjct: 13 MPIVGLGTWRSLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQEKAVMRED 72
Query: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
LFI +K+W T ++ LV A K+LK LKL+YLD+YLIHWP GFK
Sbjct: 73 LFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGD------------ 120
Query: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
P D+ +I FLD WEAME+LV GLVK +GVSNFNH Q+ERLLNK
Sbjct: 121 -------DFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNK 173
Query: 184 PGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG------GSCEGVDLIDNPV 237
PGL++KP+TNQ+ECHPYLTQ+ LI +C S+ ++VTAY PLG E L+++P
Sbjct: 174 PGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPK 233
Query: 238 IKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLN 297
IK IA +H K+ AQ+LIRF IQRNV VIP S+TP+HI ENIQVFDF+L+ +M ILS N
Sbjct: 234 IKEIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFN 293
Query: 298 RNLRLAMFPITKNHKDYPFHIEY 320
RN R F + +D+PF EY
Sbjct: 294 RNWRAFDFKEFSHLEDFPFDAEY 316
>gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]
Length = 326
Score = 278 bits (712), Expect = 4e-75
Identities = 146/328 (44%), Positives = 198/328 (60%), Gaps = 30/328 (9%)
Query: 4 IPAVGLSSW---KASP-GKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAV 59
IP +GL ++ K++P G +VK AID GYRH D AY Y NE EVG IR KI EG V
Sbjct: 18 IPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKV 77
Query: 60 RREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCS 119
RRED+F KLW T H +V ++L+ L+L+Y+DLY+I PM FKP +
Sbjct: 78 RREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIY----- 132
Query: 120 ELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLER 179
P DE+ + ++ TWEAME GLVK++GVSNFN QLE
Sbjct: 133 --------------PRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLEL 178
Query: 180 LLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCEGV-------DL 232
+LNKPGL+ KP++NQ+ECHPY TQ L+ FCQ D+ +TAY PLG S + L
Sbjct: 179 ILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPL 238
Query: 233 IDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDN 292
+ + ++ + K + K+ AQI++RF IQR V+VIP S IKEN Q+FDF LT+ +M +
Sbjct: 239 LKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKD 298
Query: 293 ILSLNRNLRLAMFPITKNHKDYPFHIEY 320
I +LN+N+R + ++H +YPFH EY
Sbjct: 299 IEALNKNVRFVELLMWRDHPEYPFHDEY 326
>gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]
Length = 323
Score = 273 bits (699), Expect = 1e-73
Identities = 142/327 (43%), Positives = 197/327 (60%), Gaps = 29/327 (8%)
Query: 4 IPAVGLSSW---KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60
+P +G ++ + + E K AI+AG+RH D AY Y+NE +VG IR KI +G+V+
Sbjct: 16 MPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVK 75
Query: 61 REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE 120
RED+F +KLWCT + +V+ A SLK L+L+Y+DLYL+H+PM KP
Sbjct: 76 REDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE--------- 126
Query: 121 LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL 180
LP DE+ VI D TWE ME GL K+IGVSNFN QLE +
Sbjct: 127 ----------TPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMI 176
Query: 181 LNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCE--GVD-----LI 233
LNKPGL++KP+ NQ+ECHPYL Q L+ FC+S+D+ + A+ LG VD L+
Sbjct: 177 LNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLL 236
Query: 234 DNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNI 293
++PV+ +AK+H ++PA I +R+Q+QR V+V+ S I+ENIQVF+F+LT DM +
Sbjct: 237 EDPVLCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVL 296
Query: 294 LSLNRNLRLAMFPITKNHKDYPFHIEY 320
LNRN R + +H DYPF EY
Sbjct: 297 DGLNRNYRYVVMDFLMDHPDYPFSDEY 323
>gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]
Length = 323
Score = 272 bits (696), Expect = 3e-73
Identities = 139/327 (42%), Positives = 200/327 (61%), Gaps = 29/327 (8%)
Query: 4 IPAVGLSSW---KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60
+P +G ++ + K EA K AI+AG+RH D A+ Y+NE +VG IR KI +G+V+
Sbjct: 16 MPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVK 75
Query: 61 REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE 120
RED+F +KLWC H+ LV A +SLK L+L+Y+DLYLIH+P+ KP
Sbjct: 76 REDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGE--------- 126
Query: 121 LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL 180
+ +P DE+ ++ D TWEA+E GL K+IGVSNFN QLE +
Sbjct: 127 ----------EVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMI 176
Query: 181 LNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCE--GVD-----LI 233
LNKPGL++KP+ NQ+ECHPY Q+ L+ FC+S+D+ + AY LG E VD L+
Sbjct: 177 LNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLL 236
Query: 234 DNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNI 293
++PV+ +AK+H ++PA I +R+Q+QR V+V+ S I++N+QVF+F+LT +M I
Sbjct: 237 EDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAI 296
Query: 294 LSLNRNLRLAMFPITKNHKDYPFHIEY 320
LNRN+R I +YPF EY
Sbjct: 297 DGLNRNVRYLTLDIFAGPPNYPFSDEY 323
>gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]
Length = 323
Score = 270 bits (689), Expect = 2e-72
Identities = 139/327 (42%), Positives = 199/327 (60%), Gaps = 29/327 (8%)
Query: 4 IPAVGLSSW---KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60
+P +G ++ + K EAVK AI+AG+ H D A+ Y+NE +VG IR KI +G+V+
Sbjct: 16 MPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVK 75
Query: 61 REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE 120
RED+F +KLW H+ LV A +SLK L+L+Y+DLYLIH+P+ KP
Sbjct: 76 REDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGE--------- 126
Query: 121 LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL 180
+ +P DE+ ++ D TWEAME GL K+IGVSNFNH LE +
Sbjct: 127 ----------EVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMI 176
Query: 181 LNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCE--GVD-----LI 233
LNKPGL++KP+ NQ+ECHPY Q+ L+ FC+S+D+ + AY LG E VD L+
Sbjct: 177 LNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLL 236
Query: 234 DNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNI 293
++PV+ +AK+H ++PA I +R+Q+QR V+V+ S I++N+QVF+F+LT +M I
Sbjct: 237 EDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAI 296
Query: 294 LSLNRNLRLAMFPITKNHKDYPFHIEY 320
LNRN+R I +YPF EY
Sbjct: 297 DGLNRNVRYLTLDIFAGPPNYPFSDEY 323
>gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]
Length = 323
Score = 270 bits (689), Expect = 2e-72
Identities = 139/327 (42%), Positives = 199/327 (60%), Gaps = 29/327 (8%)
Query: 4 IPAVGLSSW---KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60
+P +G ++ + K EAVK AI+AG+ H D A+ Y+NE +VG IR KI +G+V+
Sbjct: 16 MPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVK 75
Query: 61 REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE 120
RED+F +KLW H+ LV A +SLK L+L+Y+DLYLIH+P+ KP
Sbjct: 76 REDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGE--------- 126
Query: 121 LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL 180
+ +P DE+ ++ D TWEAME GL K+IGVSNFNH LE +
Sbjct: 127 ----------EVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMI 176
Query: 181 LNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCE--GVD-----LI 233
LNKPGL++KP+ NQ+ECHPY Q+ L+ FC+S+D+ + AY LG E VD L+
Sbjct: 177 LNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLL 236
Query: 234 DNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNI 293
++PV+ +AK+H ++PA I +R+Q+QR V+V+ S I++N+QVF+F+LT +M I
Sbjct: 237 EDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAI 296
Query: 294 LSLNRNLRLAMFPITKNHKDYPFHIEY 320
LNRN+R I +YPF EY
Sbjct: 297 DGLNRNVRYLTLDIFAGPPNYPFSDEY 323
>gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]
Length = 323
Score = 264 bits (674), Expect = 9e-71
Identities = 141/327 (43%), Positives = 196/327 (59%), Gaps = 29/327 (8%)
Query: 4 IPAVGLSSW---KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60
+P +G ++ + K E K AI+AG+RH D A+ Y+NE +VG IR KI +G+V+
Sbjct: 16 MPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVK 75
Query: 61 REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE 120
RED+F +KLW T H+ LV A SLK +L+Y+DLYLIH PM KP E
Sbjct: 76 REDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGE--------E 127
Query: 121 LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL 180
LS P DE+ VI D TWEAME GL K+IGVSNFN QLE +
Sbjct: 128 LS-----------PTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMI 176
Query: 181 LNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCE--GVD-----LI 233
LNKPGL++KP+ NQ+ECHPY + L+ FC+S+D+ + AY LG + VD L+
Sbjct: 177 LNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLL 236
Query: 234 DNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNI 293
++PV+ +AK+H ++PA I +R+Q+QR V+V+ S I++N+QVF+F+LT DM I
Sbjct: 237 EDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAI 296
Query: 294 LSLNRNLRLAMFPITKNHKDYPFHIEY 320
L+RNL +H +YP+ EY
Sbjct: 297 DGLDRNLHYFNSDSFASHPNYPYSDEY 323
>gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]
Length = 325
Score = 249 bits (637), Expect = 2e-66
Identities = 137/333 (41%), Positives = 192/333 (57%), Gaps = 37/333 (11%)
Query: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEG-AVRRE 62
+P +GL +WK+ PG+V AVK A+ GYRH DCA Y NE E+G ++ + G AV RE
Sbjct: 14 MPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPRE 73
Query: 63 DLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELS 122
+LF+ +KLW T H VE A RK+L L+L YLDLYL+HWP F+
Sbjct: 74 ELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD----------- 122
Query: 123 FCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLN 182
P + + T + +TW+A+E LV GLV+ +G+SNFN Q++ +L+
Sbjct: 123 --------NPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILS 174
Query: 183 KPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCEGVD------LIDNP 236
+R P Q+ECHPYL Q LI+ CQ+R + VTAY PLG S L++ P
Sbjct: 175 VASVR--PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEP 232
Query: 237 VIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSL 296
V+ +A+++G+SPAQIL+R+Q+QR VI IP SITPS I +NI+VFDF + +M + +L
Sbjct: 233 VVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNAL 292
Query: 297 NRNLRLAM---------FPITKNHKDYPFHIEY 320
N+N R + P H YPF+ Y
Sbjct: 293 NKNWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY 325
>gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]
Length = 325
Score = 249 bits (637), Expect = 2e-66
Identities = 137/333 (41%), Positives = 192/333 (57%), Gaps = 37/333 (11%)
Query: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEG-AVRRE 62
+P +GL +WK+ PG+V AVK A+ GYRH DCA Y NE E+G ++ + G AV RE
Sbjct: 14 MPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPRE 73
Query: 63 DLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELS 122
+LF+ +KLW T H VE A RK+L L+L YLDLYL+HWP F+
Sbjct: 74 ELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD----------- 122
Query: 123 FCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLN 182
P + + T + +TW+A+E LV GLV+ +G+SNFN Q++ +L+
Sbjct: 123 --------NPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILS 174
Query: 183 KPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCEGVD------LIDNP 236
+R P Q+ECHPYL Q LI+ CQ+R + VTAY PLG S L++ P
Sbjct: 175 VASVR--PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEP 232
Query: 237 VIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSL 296
V+ +A+++G+SPAQIL+R+Q+QR VI IP SITPS I +NI+VFDF + +M + +L
Sbjct: 233 VVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNAL 292
Query: 297 NRNLRLAM---------FPITKNHKDYPFHIEY 320
N+N R + P H YPF+ Y
Sbjct: 293 NKNWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY 325
>gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]
Length = 139
Score = 105 bits (262), Expect = 5e-23
Identities = 50/108 (46%), Positives = 72/108 (66%), Gaps = 3/108 (2%)
Query: 4 IPAVGLSSW---KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60
+P +G ++ + K EAVK AI+AG+ H D A+ Y+NE +VG IR KI +G+V+
Sbjct: 16 MPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVK 75
Query: 61 REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
RED+F +KLW H+ LV A +SLK L+L+Y+DLYLIH+P+ K
Sbjct: 76 REDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
>gi|4504825 potassium voltage-gated channel, shaker-related
subfamily, beta member 2 isoform 1 [Homo sapiens]
Length = 367
Score = 35.0 bits (79), Expect = 0.089
Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 17/115 (14%)
Query: 4 IPAVGLSSWKASPGKVTEAVKE-----AIDAGYRHFDCAYFY-HNEREVGAGIRCKIKEG 57
+ +GL +W G++T+ + E A D G FD A Y + EV G IK+
Sbjct: 49 VSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLG--NIIKKK 106
Query: 58 AVRREDLFIATKLWC--------TCHKKSLVETACRKSLKALKLNYLDLYLIHWP 104
RR L I TK++ +K ++E + SL+ L+L Y+D+ + P
Sbjct: 107 GWRRSSLVITTKIFWGGKAETERGLSRKHIIE-GLKASLERLQLEYVDVVFANRP 160
>gi|27436969 potassium voltage-gated channel, shaker-related
subfamily, beta member 2 isoform 2 [Homo sapiens]
Length = 353
Score = 35.0 bits (79), Expect = 0.089
Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 17/115 (14%)
Query: 4 IPAVGLSSWKASPGKVTEAVKE-----AIDAGYRHFDCAYFY-HNEREVGAGIRCKIKEG 57
+ +GL +W G++T+ + E A D G FD A Y + EV G IK+
Sbjct: 35 VSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLG--NIIKKK 92
Query: 58 AVRREDLFIATKLWC--------TCHKKSLVETACRKSLKALKLNYLDLYLIHWP 104
RR L I TK++ +K ++E + SL+ L+L Y+D+ + P
Sbjct: 93 GWRRSSLVITTKIFWGGKAETERGLSRKHIIE-GLKASLERLQLEYVDVVFANRP 146
>gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
Length = 292
Score = 30.0 bits (66), Expect = 2.9
Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 4/38 (10%)
Query: 54 IKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKAL 91
IK GA+R+E+++ + LW T L+ CRK L+ L
Sbjct: 246 IKGGALRQEEVYYDSSLWTTL----LIRNPCRKILEFL 279
>gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
Length = 292
Score = 30.0 bits (66), Expect = 2.9
Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 4/38 (10%)
Query: 54 IKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKAL 91
IK GA+R+E+++ + LW T L+ CRK L+ L
Sbjct: 246 IKGGALRQEEVYYDSSLWTTL----LIRNPCRKILEFL 279
>gi|4504011 glutamate-cysteine ligase regulatory protein [Homo
sapiens]
Length = 274
Score = 29.3 bits (64), Expect = 4.9
Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 2/44 (4%)
Query: 152 WEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195
WE +E+LV + + IG S+ + QLE+L + KP +NQ+
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQ--WAQVKPNSNQV 188
>gi|169163710 PREDICTED: 5'-nucleotidase domain containing 4 [Homo
sapiens]
Length = 718
Score = 28.9 bits (63), Expect = 6.4
Identities = 13/38 (34%), Positives = 18/38 (47%), Gaps = 9/38 (23%)
Query: 107 FKPPHPE---------WIMSCSELSFCLSHPRVQDLPL 135
+K PHP+ W M C +L FCL V+ P+
Sbjct: 195 WKLPHPQATGSALLKLWWMHCGDLEFCLLQKEVKPFPI 232
>gi|169163021 PREDICTED: 5'-nucleotidase domain containing 4 [Homo
sapiens]
Length = 718
Score = 28.9 bits (63), Expect = 6.4
Identities = 13/38 (34%), Positives = 18/38 (47%), Gaps = 9/38 (23%)
Query: 107 FKPPHPE---------WIMSCSELSFCLSHPRVQDLPL 135
+K PHP+ W M C +L FCL V+ P+
Sbjct: 195 WKLPHPQATGSALLKLWWMHCGDLEFCLLQKEVKPFPI 232
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,789,386
Number of Sequences: 37866
Number of extensions: 550044
Number of successful extensions: 1195
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1156
Number of HSP's gapped (non-prelim): 20
length of query: 320
length of database: 18,247,518
effective HSP length: 102
effective length of query: 218
effective length of database: 14,385,186
effective search space: 3135970548
effective search space used: 3135970548
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.