Guide to the Human Genome
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Name: GCLM Sequence: fasta or formatted (274aa) NCBI GI: 4504011
Description:

glutamate-cysteine ligase regulatory protein

Referenced in:

Glutathione Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.3         20           2
 C cysteine            2.2          6           2
 D aspartate           5.1         14           1
 E glutamate           7.7         21           2
 F phenylalanine       1.8          5           1
 G glycine             3.3          9           1
 H histidine           2.6          7           1
 I isoleucine          5.8         16           2
 K lysine              6.2         17           2
 L leucine            12.0         33           2
 M methionine          1.5          4           1
 N asparagine          4.4         12           1
 P proline             4.7         13           2
 Q glutamine           6.2         17           1
 R arginine            4.4         12           2
 S serine             10.2         28           4
 T threonine           4.0         11           1
 V valine              6.9         19           1
 W tryptophan          2.2          6           1
 Y tyrosine            1.5          4           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   glutamate-cysteine ligase regulatory protein 
SYNE1                 0.015   spectrin repeat containing, nuclear envelope 1 isofo...
SYNE1                 0.015   spectrin repeat containing, nuclear envelope 1 isof...
AKR1A1                0.011   aldo-keto reductase family 1, member A1 
AKR1A1                0.011   aldo-keto reductase family 1, member A1 
PPM1H                 0.011   protein phosphatase 1H (PP2C domain containing) [Ho...
AKR1B10L              0.010   aldo-keto reductase family 1, member B10-like [Homo...
AKR1B10               0.010   aldo-keto reductase family 1, member B10 
MACF1                 0.010   microfilament and actin filament cross-linker protei...
MACF1                 0.010   microfilament and actin filament cross-linker protei...
AKR1B1                0.010   aldo-keto reductase family 1, member B1 
RNASEL                0.010   ribonuclease L 
AKR1D1                0.010   aldo-keto reductase family 1, member D1 
CLIC2                 0.010   chloride intracellular channel 2 
AKR1CL2               0.008   aldo-keto reductase family 1, member C-like 2 
SPAG5                 0.008   sperm associated antigen 5 
RC3H2                 0.008   ring finger and CCCH-type zinc finger domains 2 iso...
RC3H2                 0.008   ring finger and CCCH-type zinc finger domains 2 iso...
GTF2IRD2              0.006   GTF2I repeat domain containing 2 
GTF2IRD2B             0.006   GTF2I repeat domain containing 2B 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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