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Search of human proteins with 93102371
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|93102371 polybromo 1 isoform 2 [Homo sapiens]
(1582 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|93102371 polybromo 1 isoform 2 [Homo sapiens] 3205 0.0
gi|30794372 polybromo 1 isoform 1 [Homo sapiens] 3093 0.0
gi|41281917 polybromo 1 isoform 4 [Homo sapiens] 2945 0.0
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r... 103 1e-21
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r... 103 1e-21
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 100 1e-20
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r... 99 3e-20
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r... 99 3e-20
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r... 99 3e-20
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r... 99 3e-20
gi|21071056 SWI/SNF-related matrix-associated actin-dependent re... 99 3e-20
gi|46399200 testis-specific bromodomain protein [Homo sapiens] 94 1e-18
gi|46399198 testis-specific bromodomain protein [Homo sapiens] 94 1e-18
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 90 2e-17
gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens] 84 1e-15
gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens] 84 1e-15
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] 82 4e-15
gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo sa... 81 7e-15
gi|16445438 bromodomain and WD repeat domain containing 1 isofor... 75 7e-13
gi|16445436 bromodomain and WD repeat domain containing 1 isofor... 75 7e-13
gi|34996489 pleckstrin homology domain interacting protein [Homo... 74 1e-12
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 67 2e-10
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 67 2e-10
gi|7706501 WW domain binding protein 11 [Homo sapiens] 62 4e-09
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 62 6e-09
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 61 7e-09
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 61 7e-09
gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens] 60 1e-08
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 60 2e-08
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 59 3e-08
>gi|93102371 polybromo 1 isoform 2 [Homo sapiens]
Length = 1582
Score = 3205 bits (8310), Expect = 0.0
Identities = 1582/1582 (100%), Positives = 1582/1582 (100%)
Query: 1 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 60
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY
Sbjct: 1 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 60
Query: 61 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 120
KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF
Sbjct: 61 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 120
Query: 121 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 180
NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
Sbjct: 121 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 180
Query: 181 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 240
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG
Sbjct: 181 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 240
Query: 241 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR 300
SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR
Sbjct: 241 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR 300
Query: 301 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA 360
TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
Sbjct: 301 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA 360
Query: 361 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY 420
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY
Sbjct: 361 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY 420
Query: 421 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM 480
YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM
Sbjct: 421 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM 480
Query: 481 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR 540
QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
Sbjct: 481 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR 540
Query: 541 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY 600
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY
Sbjct: 541 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY 600
Query: 601 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ 660
NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ
Sbjct: 601 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ 660
Query: 661 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD 720
KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
Sbjct: 661 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD 720
Query: 721 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE 780
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE
Sbjct: 721 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE 780
Query: 781 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF 840
LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF
Sbjct: 781 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF 840
Query: 841 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN 900
QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
Sbjct: 841 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN 900
Query: 901 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV 960
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV
Sbjct: 901 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV 960
Query: 961 GDYVYVEPAEANLQPHIVCIERLWEDSAEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFK 1020
GDYVYVEPAEANLQPHIVCIERLWEDSAEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFK
Sbjct: 961 GDYVYVEPAEANLQPHIVCIERLWEDSAEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFK 1020
Query: 1021 LCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANAD 1080
LCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANAD
Sbjct: 1021 LCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANAD 1080
Query: 1081 KGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVF 1140
KGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVF
Sbjct: 1081 KGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVF 1140
Query: 1141 IKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCP 1200
IKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCP
Sbjct: 1141 IKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCP 1200
Query: 1201 MTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVD 1260
MTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVD
Sbjct: 1201 MTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVD 1260
Query: 1261 DEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSESTPKSAKGSA 1320
DEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSESTPKSAKGSA
Sbjct: 1261 DEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSESTPKSAKGSA 1320
Query: 1321 KKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMM 1380
KKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMM
Sbjct: 1321 KKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMM 1380
Query: 1381 GGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMV 1440
GGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMV
Sbjct: 1381 GGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMV 1440
Query: 1441 GTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHS 1500
GTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHS
Sbjct: 1441 GTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHS 1500
Query: 1501 EAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALW 1560
EAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALW
Sbjct: 1501 EAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALW 1560
Query: 1561 RLRDLMLRDTLNIRQAYNLENV 1582
RLRDLMLRDTLNIRQAYNLENV
Sbjct: 1561 RLRDLMLRDTLNIRQAYNLENV 1582
>gi|30794372 polybromo 1 isoform 1 [Homo sapiens]
Length = 1602
Score = 3093 bits (8020), Expect = 0.0
Identities = 1549/1634 (94%), Positives = 1549/1634 (94%), Gaps = 84/1634 (5%)
Query: 1 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 60
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY
Sbjct: 1 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 60
Query: 61 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 120
KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF
Sbjct: 61 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 120
Query: 121 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 180
NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
Sbjct: 121 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 180
Query: 181 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 240
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG
Sbjct: 181 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 240
Query: 241 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR 300
SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRM
Sbjct: 241 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMS 300
Query: 301 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA 360
NKRAVQGGRLSAITMALQYGSESEEDAA
Sbjct: 301 --------------------------------NKRAVQGGRLSAITMALQYGSESEEDAA 328
Query: 361 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY 420
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY
Sbjct: 329 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY 388
Query: 421 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM 480
YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM
Sbjct: 389 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM 448
Query: 481 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR 540
QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
Sbjct: 449 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR 508
Query: 541 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY 600
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY
Sbjct: 509 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY 568
Query: 601 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ 660
NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ
Sbjct: 569 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ 628
Query: 661 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD 720
KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
Sbjct: 629 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD 688
Query: 721 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE 780
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE
Sbjct: 689 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE 748
Query: 781 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF 840
LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF
Sbjct: 749 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF 808
Query: 841 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN 900
QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
Sbjct: 809 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN 868
Query: 901 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV 960
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV
Sbjct: 869 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV 928
Query: 961 GDYVYVEPAEANLQPHIVCIERLWEDSA-------------------------EKEVFKS 995
GDYVYVEPAEANLQPHIVCIERLWEDSA EKEVFKS
Sbjct: 929 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS 988
Query: 996 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1055
DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
Sbjct: 989 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1048
Query: 1056 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN 1115
SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN
Sbjct: 1049 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN 1108
Query: 1116 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE 1175
GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE
Sbjct: 1109 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE 1168
Query: 1176 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR 1235
ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
Sbjct: 1169 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR 1228
Query: 1236 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE 1295
YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE
Sbjct: 1229 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE 1288
Query: 1296 GGDDDIEEMGEEDSE---------------------------STPKSAKGSAKKEGSKRK 1328
GGDDDIEEMGEEDSE STPKSAKGSAKKEGSKRK
Sbjct: 1289 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK 1348
Query: 1329 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLP 1388
INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLP
Sbjct: 1349 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLP 1408
Query: 1389 PLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGS 1448
PLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGS
Sbjct: 1409 PLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGS 1468
Query: 1449 PYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIE 1508
PYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIE
Sbjct: 1469 PYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIE 1528
Query: 1509 GLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLR 1568
GLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLR
Sbjct: 1529 GLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLR 1588
Query: 1569 DTLNIRQAYNLENV 1582
DTLNIRQAYNLENV
Sbjct: 1589 DTLNIRQAYNLENV 1602
>gi|41281917 polybromo 1 isoform 4 [Homo sapiens]
Length = 1582
Score = 2945 bits (7634), Expect = 0.0
Identities = 1500/1635 (91%), Positives = 1504/1635 (91%), Gaps = 106/1635 (6%)
Query: 1 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 60
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY
Sbjct: 1 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 60
Query: 61 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 120
KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF
Sbjct: 61 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 120
Query: 121 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 180
NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
Sbjct: 121 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 180
Query: 181 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 240
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG
Sbjct: 181 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 240
Query: 241 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR 300
SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR
Sbjct: 241 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR 300
Query: 301 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA 360
TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
Sbjct: 301 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA 360
Query: 361 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY 420
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY
Sbjct: 361 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY 420
Query: 421 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM 480
YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM
Sbjct: 421 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM 480
Query: 481 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR 540
QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
Sbjct: 481 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR 540
Query: 541 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY 600
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY
Sbjct: 541 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY 600
Query: 601 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ 660
NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ
Sbjct: 601 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ 660
Query: 661 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD 720
KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
Sbjct: 661 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD 720
Query: 721 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE 780
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE
Sbjct: 721 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE 780
Query: 781 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF 840
LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF
Sbjct: 781 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF 840
Query: 841 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN 900
QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
Sbjct: 841 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN 900
Query: 901 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV 960
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV
Sbjct: 901 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV 960
Query: 961 GDYVYVEPAEANLQPHIVCIERLWEDSA-------------------------EKEVFKS 995
GDYVYVEPAEANLQPHIVCIERLWEDSA EKEVFKS
Sbjct: 961 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS 1020
Query: 996 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1055
DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
Sbjct: 1021 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1080
Query: 1056 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN 1115
SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN
Sbjct: 1081 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN 1140
Query: 1116 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE 1175
GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE
Sbjct: 1141 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE 1200
Query: 1176 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR 1235
ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
Sbjct: 1201 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR 1260
Query: 1236 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE 1295
YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE
Sbjct: 1261 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE 1320
Query: 1296 GGDDDIEEMGEEDSE---------------------------STPKSAKGSAKKEGSKRK 1328
GGDDDIEEMGEEDSE STPKSAKGSAKKEGSKRK
Sbjct: 1321 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK 1380
Query: 1329 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLP 1388
INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEG+M G+
Sbjct: 1381 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGVMN---QGVA 1437
Query: 1389 PLQG-PVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGG 1447
P+ G P G G Q + GPP PP PG P P G
Sbjct: 1438 PMVGTPAPGGSPYG--QQVGVLGPPGQQAPPPYPG--------------------PHPAG 1475
Query: 1448 SPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYI 1507
P QQ PTTPMFVAPPPKTQRLLHSEAYLKYI
Sbjct: 1476 PPVIQQ----------------------------PTTPMFVAPPPKTQRLLHSEAYLKYI 1507
Query: 1508 EGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLML 1567
EGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLML
Sbjct: 1508 EGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLML 1567
Query: 1568 RDTLNIRQAYNLENV 1582
RDTLNIRQAYNLENV
Sbjct: 1568 RDTLNIRQAYNLENV 1582
>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform F [Homo sapiens]
Length = 1613
Score = 103 bits (257), Expect = 1e-21
Identities = 57/177 (32%), Positives = 97/177 (54%), Gaps = 9/177 (5%)
Query: 602 EEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL-------KLSRKSGISPKKSKY 654
EEG+ + + +K KRK S + K +K G P +
Sbjct: 1360 EEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLS 1419
Query: 655 MTP--MQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSH 712
P + +K+ ++ +AV Y D GR+LS +F++LPSR ELP+YY I+KP+D +KI+
Sbjct: 1420 PNPPNLTKKMKKIVDAVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKER 1479
Query: 713 MMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 769
+ +KY+ ++ + +D +++ NA T+N SLIY+D++VL V R+ +E ++DS
Sbjct: 1480 IRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDS 1536
Score = 95.9 bits (237), Expect = 3e-19
Identities = 58/219 (26%), Positives = 112/219 (51%), Gaps = 20/219 (9%)
Query: 159 DEDDDEDGQDNQGTVTE---GSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKV 215
D+DD+ Q +G +P L + ++++++A++ + SGR +SE+F +LPS+
Sbjct: 1399 DKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSGRQLSEVFIQLPSRK 1458
Query: 216 QYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANS 275
+ P+YY +I++P+D K I +RI+N Y+S++ + KD+ LL +NA+T+N GS +++D+
Sbjct: 1459 ELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIV 1518
Query: 276 IKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKR 335
++ +F + +IE + ++ G + GEE S+ K
Sbjct: 1519 LQSVFTSVRQKIEKEDDSE-----------------GEESEEEEEGEEEGSESESRSVKV 1561
Query: 336 AVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAE 374
++ GR L+ G + A + +SE E
Sbjct: 1562 KIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEE 1600
Score = 87.0 bits (214), Expect = 1e-16
Identities = 51/187 (27%), Positives = 102/187 (54%), Gaps = 16/187 (8%)
Query: 475 KLQQVMQAKKKELARRDDIEDGDSMISSATS--DTGSAKRKSKKNIRK------------ 520
++++ ++ KK R+ D + G S +++T D +K KK R
Sbjct: 1366 EIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNL 1425
Query: 521 -QRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK 579
++MK + + V++ ++ SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN K
Sbjct: 1426 TKKMKKIVDAVIKYKD-SSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHK 1484
Query: 580 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL 639
Y + +D+ L+ +NA+ +N EGS +Y D+ +L+ + R+++ D + S +
Sbjct: 1485 YRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEE 1544
Query: 640 KLSRKSG 646
+ + G
Sbjct: 1545 EEGEEEG 1551
Score = 85.1 bits (209), Expect = 5e-16
Identities = 47/167 (28%), Positives = 92/167 (55%), Gaps = 3/167 (1%)
Query: 388 QLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDH 447
++ D V +++ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ +++N +Y +L+
Sbjct: 1431 KIVDAVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLND 1490
Query: 448 LECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDT 507
LE D+ L+ +NA+ +N+ S IY+ + LQ V + ++++ + DD E +S +
Sbjct: 1491 LEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEE 1550
Query: 508 GSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKD 554
GS +S+ K ++K+ + R G RR KP D
Sbjct: 1551 GS---ESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSD 1594
Score = 80.1 bits (196), Expect = 2e-14
Identities = 48/170 (28%), Positives = 86/170 (50%), Gaps = 6/170 (3%)
Query: 8 ATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRL 67
+T +S+ S D DD G + N P + ++ + + YKD GR
Sbjct: 1389 STPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK--KMKKIVDAVIKYKDSSGRQ 1446
Query: 68 LCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYY 127
L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y +N L D LL NA+++
Sbjct: 1447 LSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFN 1506
Query: 128 KPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGS 177
S Y+ + L ++ R QK E +D+ + E+ ++ + EGS
Sbjct: 1507 LEGSLIYEDSIVLQSVFTSVR----QKIEKEDDSEGEESEEEEEGEEEGS 1552
Score = 52.8 bits (125), Expect = 3e-06
Identities = 38/166 (22%), Positives = 80/166 (48%), Gaps = 19/166 (11%)
Query: 772 PNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVD--PNFPN--KPPLTFDIIRK 827
PN+T +++++ +V+ ++D GR S+ ++P+ P + + P+ F I++
Sbjct: 1423 PNLTKKMKKIVD----AVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1478
Query: 828 NVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILL 887
+ N++YR L+ ++ + + + A+ N S IYED++ LQ F +R ++ K +
Sbjct: 1479 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD--- 1535
Query: 888 SPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSED 933
E+E E+ E E +K + + EK++D
Sbjct: 1536 --------SEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQD 1573
Score = 50.1 bits (118), Expect = 2e-05
Identities = 40/117 (34%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 1382 GYPPGLPPLQGPVDGLVSMGSMQPLHPGGPP-----PHHLPPGVPGLPGIPPPGVMNQGV 1436
G PG P GP G +P GGP P +PPG+PG P PP +G
Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEG- 287
Query: 1437 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY---PGPHPAGPPVIQQPTTPMFVAP 1490
PM AP +P Q++ P G+ +P P P P PP Q P P AP
Sbjct: 288 -PMANAAAPTSTP--QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP 341
Score = 46.6 bits (109), Expect = 2e-04
Identities = 38/118 (32%), Positives = 48/118 (40%), Gaps = 23/118 (19%)
Query: 1385 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1444
PG P GP G PG PP++ P G P +PPPG GV P +
Sbjct: 230 PGPGPGPGPGPG-----------PGPAPPNYSRPHGMGGPNMPPPG--PSGVPPGMPGQP 276
Query: 1445 PGGS----PYGQQVGVLGPPG--QQAPPPYPGPHPA-GPPVIQQPTTPMFVAPPPKTQ 1495
PGG P G P Q+ PP P P+ PP + +P+ PP+TQ
Sbjct: 277 PGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM---PPQTQ 331
Score = 32.3 bits (72), Expect = 3.7
Identities = 27/74 (36%), Positives = 29/74 (39%), Gaps = 14/74 (18%)
Query: 1409 GGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY 1468
G P P HL V G P PG+ Q M P P V GP P P
Sbjct: 193 GQPLPDHLQMAVQGKR--PMPGMQQQ----MPTLPPPS-------VSATGPGPGPGPGPG 239
Query: 1469 PGPHPAGPPVIQQP 1482
PGP PA PP +P
Sbjct: 240 PGPGPA-PPNYSRP 252
>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform D [Homo sapiens]
Length = 1616
Score = 103 bits (257), Expect = 1e-21
Identities = 57/177 (32%), Positives = 97/177 (54%), Gaps = 9/177 (5%)
Query: 602 EEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL-------KLSRKSGISPKKSKY 654
EEG+ + + +K KRK S + K +K G P +
Sbjct: 1363 EEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLS 1422
Query: 655 MTP--MQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSH 712
P + +K+ ++ +AV Y D GR+LS +F++LPSR ELP+YY I+KP+D +KI+
Sbjct: 1423 PNPPNLTKKMKKIVDAVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKER 1482
Query: 713 MMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 769
+ +KY+ ++ + +D +++ NA T+N SLIY+D++VL V R+ +E ++DS
Sbjct: 1483 IRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDS 1539
Score = 95.9 bits (237), Expect = 3e-19
Identities = 58/219 (26%), Positives = 112/219 (51%), Gaps = 20/219 (9%)
Query: 159 DEDDDEDGQDNQGTVTE---GSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKV 215
D+DD+ Q +G +P L + ++++++A++ + SGR +SE+F +LPS+
Sbjct: 1402 DKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSGRQLSEVFIQLPSRK 1461
Query: 216 QYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANS 275
+ P+YY +I++P+D K I +RI+N Y+S++ + KD+ LL +NA+T+N GS +++D+
Sbjct: 1462 ELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIV 1521
Query: 276 IKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKR 335
++ +F + +IE + ++ G + GEE S+ K
Sbjct: 1522 LQSVFTSVRQKIEKEDDSE-----------------GEESEEEEEGEEEGSESESRSVKV 1564
Query: 336 AVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAE 374
++ GR L+ G + A + +SE E
Sbjct: 1565 KIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEE 1603
Score = 87.0 bits (214), Expect = 1e-16
Identities = 51/187 (27%), Positives = 102/187 (54%), Gaps = 16/187 (8%)
Query: 475 KLQQVMQAKKKELARRDDIEDGDSMISSATS--DTGSAKRKSKKNIRK------------ 520
++++ ++ KK R+ D + G S +++T D +K KK R
Sbjct: 1369 EIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNL 1428
Query: 521 -QRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK 579
++MK + + V++ ++ SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN K
Sbjct: 1429 TKKMKKIVDAVIKYKD-SSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHK 1487
Query: 580 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL 639
Y + +D+ L+ +NA+ +N EGS +Y D+ +L+ + R+++ D + S +
Sbjct: 1488 YRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEE 1547
Query: 640 KLSRKSG 646
+ + G
Sbjct: 1548 EEGEEEG 1554
Score = 85.1 bits (209), Expect = 5e-16
Identities = 47/167 (28%), Positives = 92/167 (55%), Gaps = 3/167 (1%)
Query: 388 QLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDH 447
++ D V +++ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ +++N +Y +L+
Sbjct: 1434 KIVDAVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLND 1493
Query: 448 LECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDT 507
LE D+ L+ +NA+ +N+ S IY+ + LQ V + ++++ + DD E +S +
Sbjct: 1494 LEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEE 1553
Query: 508 GSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKD 554
GS +S+ K ++K+ + R G RR KP D
Sbjct: 1554 GS---ESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSD 1597
Score = 80.1 bits (196), Expect = 2e-14
Identities = 48/170 (28%), Positives = 86/170 (50%), Gaps = 6/170 (3%)
Query: 8 ATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRL 67
+T +S+ S D DD G + N P + ++ + + YKD GR
Sbjct: 1392 STPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK--KMKKIVDAVIKYKDSSGRQ 1449
Query: 68 LCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYY 127
L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y +N L D LL NA+++
Sbjct: 1450 LSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFN 1509
Query: 128 KPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGS 177
S Y+ + L ++ R QK E +D+ + E+ ++ + EGS
Sbjct: 1510 LEGSLIYEDSIVLQSVFTSVR----QKIEKEDDSEGEESEEEEEGEEEGS 1555
Score = 52.8 bits (125), Expect = 3e-06
Identities = 38/166 (22%), Positives = 80/166 (48%), Gaps = 19/166 (11%)
Query: 772 PNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVD--PNFPN--KPPLTFDIIRK 827
PN+T +++++ +V+ ++D GR S+ ++P+ P + + P+ F I++
Sbjct: 1426 PNLTKKMKKIVD----AVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1481
Query: 828 NVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILL 887
+ N++YR L+ ++ + + + A+ N S IYED++ LQ F +R ++ K +
Sbjct: 1482 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD--- 1538
Query: 888 SPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSED 933
E+E E+ E E +K + + EK++D
Sbjct: 1539 --------SEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQD 1576
Score = 50.1 bits (118), Expect = 2e-05
Identities = 40/117 (34%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 1382 GYPPGLPPLQGPVDGLVSMGSMQPLHPGGPP-----PHHLPPGVPGLPGIPPPGVMNQGV 1436
G PG P GP G +P GGP P +PPG+PG P PP +G
Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEG- 287
Query: 1437 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY---PGPHPAGPPVIQQPTTPMFVAP 1490
PM AP +P Q++ P G+ +P P P P PP Q P P AP
Sbjct: 288 -PMANAAAPTSTP--QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP 341
Score = 46.6 bits (109), Expect = 2e-04
Identities = 38/118 (32%), Positives = 48/118 (40%), Gaps = 23/118 (19%)
Query: 1385 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1444
PG P GP G PG PP++ P G P +PPPG GV P +
Sbjct: 230 PGPGPGPGPGPG-----------PGPAPPNYSRPHGMGGPNMPPPG--PSGVPPGMPGQP 276
Query: 1445 PGGS----PYGQQVGVLGPPG--QQAPPPYPGPHPA-GPPVIQQPTTPMFVAPPPKTQ 1495
PGG P G P Q+ PP P P+ PP + +P+ PP+TQ
Sbjct: 277 PGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM---PPQTQ 331
Score = 32.3 bits (72), Expect = 3.7
Identities = 27/74 (36%), Positives = 29/74 (39%), Gaps = 14/74 (18%)
Query: 1409 GGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY 1468
G P P HL V G P PG+ Q M P P V GP P P
Sbjct: 193 GQPLPDHLQMAVQGKR--PMPGMQQQ----MPTLPPPS-------VSATGPGPGPGPGPG 239
Query: 1469 PGPHPAGPPVIQQP 1482
PGP PA PP +P
Sbjct: 240 PGPGPA-PPNYSRP 252
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 100 bits (248), Expect = 1e-20
Identities = 50/153 (32%), Positives = 92/153 (60%), Gaps = 6/153 (3%)
Query: 619 KEKRKELGPLPDDDDMASPKLKLSRKSG--ISPKKSKYMTPMQQKLNEVYEAVKNYTDKR 676
+++R+ + P +D+ K + R +SP K + +++N + + V NY D
Sbjct: 1346 RKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNPPK----LTKQMNAIIDTVINYKDSS 1401
Query: 677 GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNAC 736
GR+LS +F++LPSR ELP+YY I+KP+D +KI+ + +KY+ + + +D +++ +NA
Sbjct: 1402 GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQ 1461
Query: 737 TYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 769
T+N S IY+D++VL V R+ + +E+S
Sbjct: 1462 TFNLEGSQIYEDSIVLQSVFKSARQKIAKEEES 1494
Score = 89.7 bits (221), Expect = 2e-17
Identities = 47/149 (31%), Positives = 87/149 (58%), Gaps = 5/149 (3%)
Query: 146 RTRNEFVQKGEADDEDDDEDGQDNQGTVTE---GSSPAYLKEILEQLLEAIVVATNPSGR 202
R R V K A ++D E + +G +P L + + +++ ++ + SGR
Sbjct: 1346 RKRRRNVDKDPA--KEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDSSGR 1403
Query: 203 LISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTY 262
+SE+F +LPS+ + P+YY +I++P+D K I +RI+N Y+S+ + KD+ LL NA+T+
Sbjct: 1404 QLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTF 1463
Query: 263 NEPGSQVFKDANSIKKIFYMKKAEIEHHE 291
N GSQ+++D+ ++ +F + +I E
Sbjct: 1464 NLEGSQIYEDSIVLQSVFKSARQKIAKEE 1492
Score = 89.7 bits (221), Expect = 2e-17
Identities = 46/168 (27%), Positives = 97/168 (57%), Gaps = 6/168 (3%)
Query: 389 LYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHL 448
+ DTV + +++ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ +++N +Y +L L
Sbjct: 1390 IIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDL 1449
Query: 449 ECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTG 508
E D+ L+ NA+ +N+ S IY+ + LQ V ++ ++++A+ ++ ED S +
Sbjct: 1450 EKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESED-----ESNEEEEE 1504
Query: 509 SAKRKSKKNIRKQRMKILFNVVLE-AREPGSGRRLCDLFMVKPSKKDY 555
+ +S+ + ++KI N + R+ G G++ + KP D+
Sbjct: 1505 EDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNRGKAKPVVSDF 1552
Score = 86.3 bits (212), Expect = 2e-16
Identities = 47/162 (29%), Positives = 92/162 (56%), Gaps = 4/162 (2%)
Query: 475 KLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAK-RKSKKNIRK--QRMKILFNVVL 531
++++ ++ KK++ R D + + A G K N K ++M + + V+
Sbjct: 1336 EMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVI 1395
Query: 532 EAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMK 591
++ SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN KY + +D+
Sbjct: 1396 NYKD-SSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVM 1454
Query: 592 LMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDD 633
L+ NA+ +N EGSQ+Y D+ +L+ + K R+++ + +D
Sbjct: 1455 LLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESED 1496
Score = 82.4 bits (202), Expect = 3e-15
Identities = 35/118 (29%), Positives = 74/118 (62%)
Query: 53 LYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLL 112
+ +T+ +YKD GR L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y + L
Sbjct: 1390 IIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDL 1449
Query: 113 TADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQ 170
D LL +NA+++ S Y+ + L ++ R + ++ E++DE ++E+ ++++
Sbjct: 1450 EKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEEDE 1507
Score = 54.3 bits (129), Expect = 9e-07
Identities = 38/169 (22%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 772 PNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVD--PNFPN--KPPLTFDIIRK 827
PN L +++ + + +V++++D GR S+ ++P+ P + + P+ F I++
Sbjct: 1378 PNPPKLTKQM-NAIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1436
Query: 828 NVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILL 887
+ N++YR L ++ + + A+ N S+IYED++ LQ F R ++ K E
Sbjct: 1437 RIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEE--- 1493
Query: 888 SPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSG 936
+ + + E+E +E+ E + K+K + K++ + + G
Sbjct: 1494 ------SEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKG 1536
Score = 40.4 bits (93), Expect = 0.014
Identities = 34/118 (28%), Positives = 49/118 (41%), Gaps = 10/118 (8%)
Query: 1386 GLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQ-GVAPMVGTPA 1444
G+ + P+DG+ G ++ +H G + P PG+ PP M+Q M P+
Sbjct: 69 GMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMG--PPQSPMDQHSQGYMSPHPS 126
Query: 1445 PGGSP--YGQQVGVLGPPGQQAPPPYPGP-HPAGPPVIQQPTTPMFVAPPPKTQRLLH 1499
P G+P + GP Q PP PG P P + QP P P + LH
Sbjct: 127 PLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNR----GPSPFSPVQLH 180
Score = 35.8 bits (81), Expect = 0.34
Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 2/76 (2%)
Query: 1424 PGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAP-PPYPGPHPAGP-PVIQQ 1481
P P P + + PAPGG P PP P P P P P P PV+Q
Sbjct: 262 PSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAAAVPGPSVPQPAPGQPSPVLQL 321
Query: 1482 PTTPMFVAPPPKTQRL 1497
++P K Q L
Sbjct: 322 QQKQSRISPIQKPQGL 337
Score = 32.7 bits (73), Expect = 2.9
Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 20/72 (27%)
Query: 1385 PGLPPLQGPVDGLVSMGSMQPLHP---------------GGPPPHHLPPGVPG--LPGIP 1427
PG+ P Q P+D S G M P HP GGP P +PP PG +PG P
Sbjct: 104 PGMGPPQSPMDQH-SQGYMSP-HPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDP 161
Query: 1428 PP-GVMNQGVAP 1438
N+G +P
Sbjct: 162 QAMSQPNRGPSP 173
>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform A [Homo sapiens]
Length = 1679
Score = 99.0 bits (245), Expect = 3e-20
Identities = 57/178 (32%), Positives = 97/178 (54%), Gaps = 10/178 (5%)
Query: 602 EEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL-------KLSRKSGISPKKSKY 654
EEG+ + + +K KRK S + K +K G P +
Sbjct: 1425 EEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLS 1484
Query: 655 MTP--MQQKLNEVYEAVKNYTDKR-GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRS 711
P + +K+ ++ +AV Y D GR+LS +F++LPSR ELP+YY I+KP+D +KI+
Sbjct: 1485 PNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1544
Query: 712 HMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 769
+ +KY+ ++ + +D +++ NA T+N SLIY+D++VL V R+ +E ++DS
Sbjct: 1545 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDS 1602
Score = 92.0 bits (227), Expect = 4e-18
Identities = 58/220 (26%), Positives = 112/220 (50%), Gaps = 21/220 (9%)
Query: 159 DEDDDEDGQDNQGTVTE---GSSPAYLKEILEQLLEAIV-VATNPSGRLISELFQKLPSK 214
D+DD+ Q +G +P L + ++++++A++ + SGR +SE+F +LPS+
Sbjct: 1464 DKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSR 1523
Query: 215 VQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDAN 274
+ P+YY +I++P+D K I +RI+N Y+S++ + KD+ LL +NA+T+N GS +++D+
Sbjct: 1524 KELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSI 1583
Query: 275 SIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNK 334
++ +F + +IE + ++ G + GEE S+ K
Sbjct: 1584 VLQSVFTSVRQKIEKEDDSE-----------------GEESEEEEEGEEEGSESESRSVK 1626
Query: 335 RAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAE 374
++ GR L+ G + A + +SE E
Sbjct: 1627 VKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEE 1666
Score = 91.3 bits (225), Expect = 7e-18
Identities = 51/187 (27%), Positives = 102/187 (54%), Gaps = 15/187 (8%)
Query: 475 KLQQVMQAKKKELARRDDIEDGDSMISSATS--DTGSAKRKSKKNIRK------------ 520
++++ ++ KK R+ D + G S +++T D +K KK R
Sbjct: 1431 EIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNL 1490
Query: 521 -QRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK 579
++MK + + V++ ++ SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN K
Sbjct: 1491 TKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHK 1550
Query: 580 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL 639
Y + +D+ L+ +NA+ +N EGS +Y D+ +L+ + R+++ D + S +
Sbjct: 1551 YRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEE 1610
Query: 640 KLSRKSG 646
+ + G
Sbjct: 1611 EEGEEEG 1617
Score = 81.6 bits (200), Expect = 5e-15
Identities = 45/157 (28%), Positives = 87/157 (55%), Gaps = 3/157 (1%)
Query: 398 NNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFE 457
++ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ +++N +Y +L+ LE D+ L+ +
Sbjct: 1507 SSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQ 1566
Query: 458 NAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKN 517
NA+ +N+ S IY+ + LQ V + ++++ + DD E +S + GS +S+
Sbjct: 1567 NAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGS---ESESR 1623
Query: 518 IRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKD 554
K ++K+ + R G RR KP D
Sbjct: 1624 SVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSD 1660
Score = 75.5 bits (184), Expect = 4e-13
Identities = 48/171 (28%), Positives = 86/171 (50%), Gaps = 7/171 (4%)
Query: 8 ATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQ-GR 66
+T +S+ S D DD G + N P + ++ + + YKD GR
Sbjct: 1454 STPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK--KMKKIVDAVIKYKDSSSGR 1511
Query: 67 LLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSY 126
L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y +N L D LL NA+++
Sbjct: 1512 QLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTF 1571
Query: 127 YKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGS 177
S Y+ + L ++ R QK E +D+ + E+ ++ + EGS
Sbjct: 1572 NLEGSLIYEDSIVLQSVFTSVR----QKIEKEDDSEGEESEEEEEGEEEGS 1618
Score = 50.1 bits (118), Expect = 2e-05
Identities = 40/117 (34%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 1382 GYPPGLPPLQGPVDGLVSMGSMQPLHPGGPP-----PHHLPPGVPGLPGIPPPGVMNQGV 1436
G PG P GP G +P GGP P +PPG+PG P PP +G
Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEG- 287
Query: 1437 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY---PGPHPAGPPVIQQPTTPMFVAP 1490
PM AP +P Q++ P G+ +P P P P PP Q P P AP
Sbjct: 288 -PMANAAAPTSTP--QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP 341
Score = 48.1 bits (113), Expect = 7e-05
Identities = 38/167 (22%), Positives = 80/167 (47%), Gaps = 20/167 (11%)
Query: 772 PNVTLLIQELIHNLFVSVMSHQDDE-GRCYSDSLAEIPAVD--PNFPN--KPPLTFDIIR 826
PN+T +++++ +V+ ++D GR S+ ++P+ P + + P+ F I+
Sbjct: 1488 PNLTKKMKKIVD----AVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIK 1543
Query: 827 KNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEIL 886
+ + N++YR L+ ++ + + + A+ N S IYED++ LQ F +R ++ K +
Sbjct: 1544 ERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD-- 1601
Query: 887 LSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSED 933
E+E E+ E E +K + + EK++D
Sbjct: 1602 ---------SEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQD 1639
Score = 46.6 bits (109), Expect = 2e-04
Identities = 38/118 (32%), Positives = 48/118 (40%), Gaps = 23/118 (19%)
Query: 1385 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1444
PG P GP G PG PP++ P G P +PPPG GV P +
Sbjct: 230 PGPGPGPGPGPG-----------PGPAPPNYSRPHGMGGPNMPPPG--PSGVPPGMPGQP 276
Query: 1445 PGGS----PYGQQVGVLGPPG--QQAPPPYPGPHPA-GPPVIQQPTTPMFVAPPPKTQ 1495
PGG P G P Q+ PP P P+ PP + +P+ PP+TQ
Sbjct: 277 PGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM---PPQTQ 331
Score = 32.3 bits (72), Expect = 3.7
Identities = 27/74 (36%), Positives = 29/74 (39%), Gaps = 14/74 (18%)
Query: 1409 GGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY 1468
G P P HL V G P PG+ Q M P P V GP P P
Sbjct: 193 GQPLPDHLQMAVQGKR--PMPGMQQQ----MPTLPPPS-------VSATGPGPGPGPGPG 239
Query: 1469 PGPHPAGPPVIQQP 1482
PGP PA PP +P
Sbjct: 240 PGPGPA-PPNYSRP 252
>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform E [Homo sapiens]
Length = 1614
Score = 99.0 bits (245), Expect = 3e-20
Identities = 57/178 (32%), Positives = 97/178 (54%), Gaps = 10/178 (5%)
Query: 602 EEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL-------KLSRKSGISPKKSKY 654
EEG+ + + +K KRK S + K +K G P +
Sbjct: 1360 EEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLS 1419
Query: 655 MTP--MQQKLNEVYEAVKNYTDKR-GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRS 711
P + +K+ ++ +AV Y D GR+LS +F++LPSR ELP+YY I+KP+D +KI+
Sbjct: 1420 PNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1479
Query: 712 HMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 769
+ +KY+ ++ + +D +++ NA T+N SLIY+D++VL V R+ +E ++DS
Sbjct: 1480 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDS 1537
Score = 92.0 bits (227), Expect = 4e-18
Identities = 58/220 (26%), Positives = 112/220 (50%), Gaps = 21/220 (9%)
Query: 159 DEDDDEDGQDNQGTVTE---GSSPAYLKEILEQLLEAIV-VATNPSGRLISELFQKLPSK 214
D+DD+ Q +G +P L + ++++++A++ + SGR +SE+F +LPS+
Sbjct: 1399 DKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSR 1458
Query: 215 VQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDAN 274
+ P+YY +I++P+D K I +RI+N Y+S++ + KD+ LL +NA+T+N GS +++D+
Sbjct: 1459 KELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSI 1518
Query: 275 SIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNK 334
++ +F + +IE + ++ G + GEE S+ K
Sbjct: 1519 VLQSVFTSVRQKIEKEDDSE-----------------GEESEEEEEGEEEGSESESRSVK 1561
Query: 335 RAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAE 374
++ GR L+ G + A + +SE E
Sbjct: 1562 VKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEE 1601
Score = 91.3 bits (225), Expect = 7e-18
Identities = 51/187 (27%), Positives = 102/187 (54%), Gaps = 15/187 (8%)
Query: 475 KLQQVMQAKKKELARRDDIEDGDSMISSATS--DTGSAKRKSKKNIRK------------ 520
++++ ++ KK R+ D + G S +++T D +K KK R
Sbjct: 1366 EIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNL 1425
Query: 521 -QRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK 579
++MK + + V++ ++ SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN K
Sbjct: 1426 TKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHK 1485
Query: 580 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL 639
Y + +D+ L+ +NA+ +N EGS +Y D+ +L+ + R+++ D + S +
Sbjct: 1486 YRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEE 1545
Query: 640 KLSRKSG 646
+ + G
Sbjct: 1546 EEGEEEG 1552
Score = 81.6 bits (200), Expect = 5e-15
Identities = 45/157 (28%), Positives = 87/157 (55%), Gaps = 3/157 (1%)
Query: 398 NNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFE 457
++ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ +++N +Y +L+ LE D+ L+ +
Sbjct: 1442 SSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQ 1501
Query: 458 NAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKN 517
NA+ +N+ S IY+ + LQ V + ++++ + DD E +S + GS +S+
Sbjct: 1502 NAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGS---ESESR 1558
Query: 518 IRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKD 554
K ++K+ + R G RR KP D
Sbjct: 1559 SVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSD 1595
Score = 75.5 bits (184), Expect = 4e-13
Identities = 48/171 (28%), Positives = 86/171 (50%), Gaps = 7/171 (4%)
Query: 8 ATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQ-GR 66
+T +S+ S D DD G + N P + ++ + + YKD GR
Sbjct: 1389 STPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK--KMKKIVDAVIKYKDSSSGR 1446
Query: 67 LLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSY 126
L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y +N L D LL NA+++
Sbjct: 1447 QLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTF 1506
Query: 127 YKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGS 177
S Y+ + L ++ R QK E +D+ + E+ ++ + EGS
Sbjct: 1507 NLEGSLIYEDSIVLQSVFTSVR----QKIEKEDDSEGEESEEEEEGEEEGS 1553
Score = 50.1 bits (118), Expect = 2e-05
Identities = 40/117 (34%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 1382 GYPPGLPPLQGPVDGLVSMGSMQPLHPGGPP-----PHHLPPGVPGLPGIPPPGVMNQGV 1436
G PG P GP G +P GGP P +PPG+PG P PP +G
Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEG- 287
Query: 1437 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY---PGPHPAGPPVIQQPTTPMFVAP 1490
PM AP +P Q++ P G+ +P P P P PP Q P P AP
Sbjct: 288 -PMANAAAPTSTP--QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP 341
Score = 48.1 bits (113), Expect = 7e-05
Identities = 38/167 (22%), Positives = 80/167 (47%), Gaps = 20/167 (11%)
Query: 772 PNVTLLIQELIHNLFVSVMSHQDDE-GRCYSDSLAEIPAVD--PNFPN--KPPLTFDIIR 826
PN+T +++++ +V+ ++D GR S+ ++P+ P + + P+ F I+
Sbjct: 1423 PNLTKKMKKIVD----AVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIK 1478
Query: 827 KNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEIL 886
+ + N++YR L+ ++ + + + A+ N S IYED++ LQ F +R ++ K +
Sbjct: 1479 ERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD-- 1536
Query: 887 LSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSED 933
E+E E+ E E +K + + EK++D
Sbjct: 1537 ---------SEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQD 1574
Score = 46.6 bits (109), Expect = 2e-04
Identities = 38/118 (32%), Positives = 48/118 (40%), Gaps = 23/118 (19%)
Query: 1385 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1444
PG P GP G PG PP++ P G P +PPPG GV P +
Sbjct: 230 PGPGPGPGPGPG-----------PGPAPPNYSRPHGMGGPNMPPPG--PSGVPPGMPGQP 276
Query: 1445 PGGS----PYGQQVGVLGPPG--QQAPPPYPGPHPA-GPPVIQQPTTPMFVAPPPKTQ 1495
PGG P G P Q+ PP P P+ PP + +P+ PP+TQ
Sbjct: 277 PGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM---PPQTQ 331
Score = 32.3 bits (72), Expect = 3.7
Identities = 27/74 (36%), Positives = 29/74 (39%), Gaps = 14/74 (18%)
Query: 1409 GGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY 1468
G P P HL V G P PG+ Q M P P V GP P P
Sbjct: 193 GQPLPDHLQMAVQGKR--PMPGMQQQ----MPTLPPPS-------VSATGPGPGPGPGPG 239
Query: 1469 PGPHPAGPPVIQQP 1482
PGP PA PP +P
Sbjct: 240 PGPGPA-PPNYSRP 252
>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform C [Homo sapiens]
Length = 1617
Score = 99.0 bits (245), Expect = 3e-20
Identities = 57/178 (32%), Positives = 97/178 (54%), Gaps = 10/178 (5%)
Query: 602 EEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL-------KLSRKSGISPKKSKY 654
EEG+ + + +K KRK S + K +K G P +
Sbjct: 1363 EEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLS 1422
Query: 655 MTP--MQQKLNEVYEAVKNYTDKR-GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRS 711
P + +K+ ++ +AV Y D GR+LS +F++LPSR ELP+YY I+KP+D +KI+
Sbjct: 1423 PNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1482
Query: 712 HMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 769
+ +KY+ ++ + +D +++ NA T+N SLIY+D++VL V R+ +E ++DS
Sbjct: 1483 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDS 1540
Score = 92.0 bits (227), Expect = 4e-18
Identities = 58/220 (26%), Positives = 112/220 (50%), Gaps = 21/220 (9%)
Query: 159 DEDDDEDGQDNQGTVTE---GSSPAYLKEILEQLLEAIV-VATNPSGRLISELFQKLPSK 214
D+DD+ Q +G +P L + ++++++A++ + SGR +SE+F +LPS+
Sbjct: 1402 DKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSR 1461
Query: 215 VQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDAN 274
+ P+YY +I++P+D K I +RI+N Y+S++ + KD+ LL +NA+T+N GS +++D+
Sbjct: 1462 KELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSI 1521
Query: 275 SIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNK 334
++ +F + +IE + ++ G + GEE S+ K
Sbjct: 1522 VLQSVFTSVRQKIEKEDDSE-----------------GEESEEEEEGEEEGSESESRSVK 1564
Query: 335 RAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAE 374
++ GR L+ G + A + +SE E
Sbjct: 1565 VKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEE 1604
Score = 91.3 bits (225), Expect = 7e-18
Identities = 51/187 (27%), Positives = 102/187 (54%), Gaps = 15/187 (8%)
Query: 475 KLQQVMQAKKKELARRDDIEDGDSMISSATS--DTGSAKRKSKKNIRK------------ 520
++++ ++ KK R+ D + G S +++T D +K KK R
Sbjct: 1369 EIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNL 1428
Query: 521 -QRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK 579
++MK + + V++ ++ SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN K
Sbjct: 1429 TKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHK 1488
Query: 580 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL 639
Y + +D+ L+ +NA+ +N EGS +Y D+ +L+ + R+++ D + S +
Sbjct: 1489 YRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEE 1548
Query: 640 KLSRKSG 646
+ + G
Sbjct: 1549 EEGEEEG 1555
Score = 81.6 bits (200), Expect = 5e-15
Identities = 45/157 (28%), Positives = 87/157 (55%), Gaps = 3/157 (1%)
Query: 398 NNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFE 457
++ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ +++N +Y +L+ LE D+ L+ +
Sbjct: 1445 SSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQ 1504
Query: 458 NAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKN 517
NA+ +N+ S IY+ + LQ V + ++++ + DD E +S + GS +S+
Sbjct: 1505 NAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGS---ESESR 1561
Query: 518 IRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKD 554
K ++K+ + R G RR KP D
Sbjct: 1562 SVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSD 1598
Score = 75.5 bits (184), Expect = 4e-13
Identities = 48/171 (28%), Positives = 86/171 (50%), Gaps = 7/171 (4%)
Query: 8 ATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQ-GR 66
+T +S+ S D DD G + N P + ++ + + YKD GR
Sbjct: 1392 STPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK--KMKKIVDAVIKYKDSSSGR 1449
Query: 67 LLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSY 126
L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y +N L D LL NA+++
Sbjct: 1450 QLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTF 1509
Query: 127 YKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGS 177
S Y+ + L ++ R QK E +D+ + E+ ++ + EGS
Sbjct: 1510 NLEGSLIYEDSIVLQSVFTSVR----QKIEKEDDSEGEESEEEEEGEEEGS 1556
Score = 50.1 bits (118), Expect = 2e-05
Identities = 40/117 (34%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 1382 GYPPGLPPLQGPVDGLVSMGSMQPLHPGGPP-----PHHLPPGVPGLPGIPPPGVMNQGV 1436
G PG P GP G +P GGP P +PPG+PG P PP +G
Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEG- 287
Query: 1437 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY---PGPHPAGPPVIQQPTTPMFVAP 1490
PM AP +P Q++ P G+ +P P P P PP Q P P AP
Sbjct: 288 -PMANAAAPTSTP--QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP 341
Score = 48.1 bits (113), Expect = 7e-05
Identities = 38/167 (22%), Positives = 80/167 (47%), Gaps = 20/167 (11%)
Query: 772 PNVTLLIQELIHNLFVSVMSHQDDE-GRCYSDSLAEIPAVD--PNFPN--KPPLTFDIIR 826
PN+T +++++ +V+ ++D GR S+ ++P+ P + + P+ F I+
Sbjct: 1426 PNLTKKMKKIVD----AVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIK 1481
Query: 827 KNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEIL 886
+ + N++YR L+ ++ + + + A+ N S IYED++ LQ F +R ++ K +
Sbjct: 1482 ERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD-- 1539
Query: 887 LSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSED 933
E+E E+ E E +K + + EK++D
Sbjct: 1540 ---------SEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQD 1577
Score = 46.6 bits (109), Expect = 2e-04
Identities = 38/118 (32%), Positives = 48/118 (40%), Gaps = 23/118 (19%)
Query: 1385 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1444
PG P GP G PG PP++ P G P +PPPG GV P +
Sbjct: 230 PGPGPGPGPGPG-----------PGPAPPNYSRPHGMGGPNMPPPG--PSGVPPGMPGQP 276
Query: 1445 PGGS----PYGQQVGVLGPPG--QQAPPPYPGPHPA-GPPVIQQPTTPMFVAPPPKTQ 1495
PGG P G P Q+ PP P P+ PP + +P+ PP+TQ
Sbjct: 277 PGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM---PPQTQ 331
Score = 32.3 bits (72), Expect = 3.7
Identities = 27/74 (36%), Positives = 29/74 (39%), Gaps = 14/74 (18%)
Query: 1409 GGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY 1468
G P P HL V G P PG+ Q M P P V GP P P
Sbjct: 193 GQPLPDHLQMAVQGKR--PMPGMQQQ----MPTLPPPS-------VSATGPGPGPGPGPG 239
Query: 1469 PGPHPAGPPVIQQP 1482
PGP PA PP +P
Sbjct: 240 PGPGPA-PPNYSRP 252
>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform B [Homo sapiens]
Length = 1647
Score = 99.0 bits (245), Expect = 3e-20
Identities = 57/178 (32%), Positives = 97/178 (54%), Gaps = 10/178 (5%)
Query: 602 EEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL-------KLSRKSGISPKKSKY 654
EEG+ + + +K KRK S + K +K G P +
Sbjct: 1393 EEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLS 1452
Query: 655 MTP--MQQKLNEVYEAVKNYTDKR-GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRS 711
P + +K+ ++ +AV Y D GR+LS +F++LPSR ELP+YY I+KP+D +KI+
Sbjct: 1453 PNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1512
Query: 712 HMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 769
+ +KY+ ++ + +D +++ NA T+N SLIY+D++VL V R+ +E ++DS
Sbjct: 1513 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDS 1570
Score = 92.0 bits (227), Expect = 4e-18
Identities = 58/220 (26%), Positives = 112/220 (50%), Gaps = 21/220 (9%)
Query: 159 DEDDDEDGQDNQGTVTE---GSSPAYLKEILEQLLEAIV-VATNPSGRLISELFQKLPSK 214
D+DD+ Q +G +P L + ++++++A++ + SGR +SE+F +LPS+
Sbjct: 1432 DKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSR 1491
Query: 215 VQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDAN 274
+ P+YY +I++P+D K I +RI+N Y+S++ + KD+ LL +NA+T+N GS +++D+
Sbjct: 1492 KELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSI 1551
Query: 275 SIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNK 334
++ +F + +IE + ++ G + GEE S+ K
Sbjct: 1552 VLQSVFTSVRQKIEKEDDSE-----------------GEESEEEEEGEEEGSESESRSVK 1594
Query: 335 RAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAE 374
++ GR L+ G + A + +SE E
Sbjct: 1595 VKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEE 1634
Score = 91.3 bits (225), Expect = 7e-18
Identities = 51/187 (27%), Positives = 102/187 (54%), Gaps = 15/187 (8%)
Query: 475 KLQQVMQAKKKELARRDDIEDGDSMISSATS--DTGSAKRKSKKNIRK------------ 520
++++ ++ KK R+ D + G S +++T D +K KK R
Sbjct: 1399 EIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNL 1458
Query: 521 -QRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK 579
++MK + + V++ ++ SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN K
Sbjct: 1459 TKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHK 1518
Query: 580 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL 639
Y + +D+ L+ +NA+ +N EGS +Y D+ +L+ + R+++ D + S +
Sbjct: 1519 YRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEE 1578
Query: 640 KLSRKSG 646
+ + G
Sbjct: 1579 EEGEEEG 1585
Score = 81.6 bits (200), Expect = 5e-15
Identities = 45/157 (28%), Positives = 87/157 (55%), Gaps = 3/157 (1%)
Query: 398 NNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFE 457
++ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ +++N +Y +L+ LE D+ L+ +
Sbjct: 1475 SSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQ 1534
Query: 458 NAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKN 517
NA+ +N+ S IY+ + LQ V + ++++ + DD E +S + GS +S+
Sbjct: 1535 NAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGS---ESESR 1591
Query: 518 IRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKD 554
K ++K+ + R G RR KP D
Sbjct: 1592 SVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSD 1628
Score = 75.5 bits (184), Expect = 4e-13
Identities = 48/171 (28%), Positives = 86/171 (50%), Gaps = 7/171 (4%)
Query: 8 ATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQ-GR 66
+T +S+ S D DD G + N P + ++ + + YKD GR
Sbjct: 1422 STPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK--KMKKIVDAVIKYKDSSSGR 1479
Query: 67 LLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSY 126
L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y +N L D LL NA+++
Sbjct: 1480 QLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTF 1539
Query: 127 YKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGS 177
S Y+ + L ++ R QK E +D+ + E+ ++ + EGS
Sbjct: 1540 NLEGSLIYEDSIVLQSVFTSVR----QKIEKEDDSEGEESEEEEEGEEEGS 1586
Score = 50.1 bits (118), Expect = 2e-05
Identities = 40/117 (34%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 1382 GYPPGLPPLQGPVDGLVSMGSMQPLHPGGPP-----PHHLPPGVPGLPGIPPPGVMNQGV 1436
G PG P GP G +P GGP P +PPG+PG P PP +G
Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEG- 287
Query: 1437 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY---PGPHPAGPPVIQQPTTPMFVAP 1490
PM AP +P Q++ P G+ +P P P P PP Q P P AP
Sbjct: 288 -PMANAAAPTSTP--QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP 341
Score = 48.1 bits (113), Expect = 7e-05
Identities = 38/167 (22%), Positives = 80/167 (47%), Gaps = 20/167 (11%)
Query: 772 PNVTLLIQELIHNLFVSVMSHQDDE-GRCYSDSLAEIPAVD--PNFPN--KPPLTFDIIR 826
PN+T +++++ +V+ ++D GR S+ ++P+ P + + P+ F I+
Sbjct: 1456 PNLTKKMKKIVD----AVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIK 1511
Query: 827 KNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEIL 886
+ + N++YR L+ ++ + + + A+ N S IYED++ LQ F +R ++ K +
Sbjct: 1512 ERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD-- 1569
Query: 887 LSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSED 933
E+E E+ E E +K + + EK++D
Sbjct: 1570 ---------SEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQD 1607
Score = 46.6 bits (109), Expect = 2e-04
Identities = 38/118 (32%), Positives = 48/118 (40%), Gaps = 23/118 (19%)
Query: 1385 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1444
PG P GP G PG PP++ P G P +PPPG GV P +
Sbjct: 230 PGPGPGPGPGPG-----------PGPAPPNYSRPHGMGGPNMPPPG--PSGVPPGMPGQP 276
Query: 1445 PGGS----PYGQQVGVLGPPG--QQAPPPYPGPHPA-GPPVIQQPTTPMFVAPPPKTQ 1495
PGG P G P Q+ PP P P+ PP + +P+ PP+TQ
Sbjct: 277 PGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM---PPQTQ 331
Score = 32.3 bits (72), Expect = 3.7
Identities = 27/74 (36%), Positives = 29/74 (39%), Gaps = 14/74 (18%)
Query: 1409 GGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY 1468
G P P HL V G P PG+ Q M P P V GP P P
Sbjct: 193 GQPLPDHLQMAVQGKR--PMPGMQQQ----MPTLPPPS-------VSATGPGPGPGPGPG 239
Query: 1469 PGPHPAGPPVIQQP 1482
PGP PA PP +P
Sbjct: 240 PGPGPA-PPNYSRP 252
>gi|21071056 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform B [Homo sapiens]
Length = 1647
Score = 99.0 bits (245), Expect = 3e-20
Identities = 57/178 (32%), Positives = 97/178 (54%), Gaps = 10/178 (5%)
Query: 602 EEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL-------KLSRKSGISPKKSKY 654
EEG+ + + +K KRK S + K +K G P +
Sbjct: 1393 EEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLS 1452
Query: 655 MTP--MQQKLNEVYEAVKNYTDKR-GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRS 711
P + +K+ ++ +AV Y D GR+LS +F++LPSR ELP+YY I+KP+D +KI+
Sbjct: 1453 PNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1512
Query: 712 HMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 769
+ +KY+ ++ + +D +++ NA T+N SLIY+D++VL V R+ +E ++DS
Sbjct: 1513 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDS 1570
Score = 92.0 bits (227), Expect = 4e-18
Identities = 58/220 (26%), Positives = 112/220 (50%), Gaps = 21/220 (9%)
Query: 159 DEDDDEDGQDNQGTVTE---GSSPAYLKEILEQLLEAIV-VATNPSGRLISELFQKLPSK 214
D+DD+ Q +G +P L + ++++++A++ + SGR +SE+F +LPS+
Sbjct: 1432 DKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSR 1491
Query: 215 VQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDAN 274
+ P+YY +I++P+D K I +RI+N Y+S++ + KD+ LL +NA+T+N GS +++D+
Sbjct: 1492 KELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSI 1551
Query: 275 SIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNK 334
++ +F + +IE + ++ G + GEE S+ K
Sbjct: 1552 VLQSVFTSVRQKIEKEDDSE-----------------GEESEEEEEGEEEGSESESRSVK 1594
Query: 335 RAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAE 374
++ GR L+ G + A + +SE E
Sbjct: 1595 VKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEE 1634
Score = 91.3 bits (225), Expect = 7e-18
Identities = 51/187 (27%), Positives = 102/187 (54%), Gaps = 15/187 (8%)
Query: 475 KLQQVMQAKKKELARRDDIEDGDSMISSATS--DTGSAKRKSKKNIRK------------ 520
++++ ++ KK R+ D + G S +++T D +K KK R
Sbjct: 1399 EIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNL 1458
Query: 521 -QRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK 579
++MK + + V++ ++ SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN K
Sbjct: 1459 TKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHK 1518
Query: 580 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL 639
Y + +D+ L+ +NA+ +N EGS +Y D+ +L+ + R+++ D + S +
Sbjct: 1519 YRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEE 1578
Query: 640 KLSRKSG 646
+ + G
Sbjct: 1579 EEGEEEG 1585
Score = 81.6 bits (200), Expect = 5e-15
Identities = 45/157 (28%), Positives = 87/157 (55%), Gaps = 3/157 (1%)
Query: 398 NNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFE 457
++ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ +++N +Y +L+ LE D+ L+ +
Sbjct: 1475 SSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQ 1534
Query: 458 NAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKN 517
NA+ +N+ S IY+ + LQ V + ++++ + DD E +S + GS +S+
Sbjct: 1535 NAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGS---ESESR 1591
Query: 518 IRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKD 554
K ++K+ + R G RR KP D
Sbjct: 1592 SVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSD 1628
Score = 75.5 bits (184), Expect = 4e-13
Identities = 48/171 (28%), Positives = 86/171 (50%), Gaps = 7/171 (4%)
Query: 8 ATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQ-GR 66
+T +S+ S D DD G + N P + ++ + + YKD GR
Sbjct: 1422 STPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK--KMKKIVDAVIKYKDSSSGR 1479
Query: 67 LLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSY 126
L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y +N L D LL NA+++
Sbjct: 1480 QLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTF 1539
Query: 127 YKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGS 177
S Y+ + L ++ R QK E +D+ + E+ ++ + EGS
Sbjct: 1540 NLEGSLIYEDSIVLQSVFTSVR----QKIEKEDDSEGEESEEEEEGEEEGS 1586
Score = 50.1 bits (118), Expect = 2e-05
Identities = 40/117 (34%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 1382 GYPPGLPPLQGPVDGLVSMGSMQPLHPGGPP-----PHHLPPGVPGLPGIPPPGVMNQGV 1436
G PG P GP G +P GGP P +PPG+PG P PP +G
Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEG- 287
Query: 1437 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY---PGPHPAGPPVIQQPTTPMFVAP 1490
PM AP +P Q++ P G+ +P P P P PP Q P P AP
Sbjct: 288 -PMANAAAPTSTP--QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP 341
Score = 48.1 bits (113), Expect = 7e-05
Identities = 38/167 (22%), Positives = 80/167 (47%), Gaps = 20/167 (11%)
Query: 772 PNVTLLIQELIHNLFVSVMSHQDDE-GRCYSDSLAEIPAVD--PNFPN--KPPLTFDIIR 826
PN+T +++++ +V+ ++D GR S+ ++P+ P + + P+ F I+
Sbjct: 1456 PNLTKKMKKIVD----AVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIK 1511
Query: 827 KNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEIL 886
+ + N++YR L+ ++ + + + A+ N S IYED++ LQ F +R ++ K +
Sbjct: 1512 ERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD-- 1569
Query: 887 LSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSED 933
E+E E+ E E +K + + EK++D
Sbjct: 1570 ---------SEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQD 1607
Score = 46.6 bits (109), Expect = 2e-04
Identities = 38/118 (32%), Positives = 48/118 (40%), Gaps = 23/118 (19%)
Query: 1385 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1444
PG P GP G PG PP++ P G P +PPPG GV P +
Sbjct: 230 PGPGPGPGPGPG-----------PGPAPPNYSRPHGMGGPNMPPPG--PSGVPPGMPGQP 276
Query: 1445 PGGS----PYGQQVGVLGPPG--QQAPPPYPGPHPA-GPPVIQQPTTPMFVAPPPKTQ 1495
PGG P G P Q+ PP P P+ PP + +P+ PP+TQ
Sbjct: 277 PGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM---PPQTQ 331
Score = 32.3 bits (72), Expect = 3.7
Identities = 27/74 (36%), Positives = 29/74 (39%), Gaps = 14/74 (18%)
Query: 1409 GGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY 1468
G P P HL V G P PG+ Q M P P V GP P P
Sbjct: 193 GQPLPDHLQMAVQGKR--PMPGMQQQ----MPTLPPPS-------VSATGPGPGPGPGPG 239
Query: 1469 PGPHPAGPPVIQQP 1482
PGP PA PP +P
Sbjct: 240 PGPGPA-PPNYSRP 252
>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 93.6 bits (231), Expect = 1e-18
Identities = 77/311 (24%), Positives = 130/311 (41%), Gaps = 43/311 (13%)
Query: 214 KVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDA 273
K+Q PDYY IIK P+DL TI +R++N Y +D + + N YN+PG + A
Sbjct: 60 KLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMA 119
Query: 274 NSIKKIFYMKKAEIEHHEM---AKSSLRMRTPSNLA---AARLTGPSHSKGSLGEERNPT 327
+++K+F K +++ E K ++ T N+A A + PS ++ ++ P+
Sbjct: 120 QALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQQEIPS 179
Query: 328 ---SKYYRNKRAVQGGRLSAITMA---LQYGSESEEDAALAAARYEEGESEAESITSFMD 381
VQG +++ + + G + + D A + SE +
Sbjct: 180 VFPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKS 239
Query: 382 VSNP-------------FYQLYDTV---------RSCRNNQGQLIAE-------PFYHLP 412
V+ P Q Y+ V R C +++A+ PFY+
Sbjct: 240 VALPPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPV 299
Query: 413 SKKK--YPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIY 470
+YY +K P+ L I+ K+ NQEY+ D+ LMF N +YN P+ +
Sbjct: 300 DVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVV 359
Query: 471 KRVLKLQQVMQ 481
LQ V +
Sbjct: 360 TMARMLQDVFE 370
Score = 62.0 bits (149), Expect = 4e-09
Identities = 75/349 (21%), Positives = 129/349 (36%), Gaps = 47/349 (13%)
Query: 414 KKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRV 473
K + PDYY IK P+ L I+ +L+N+ Y D N MF N YN P I
Sbjct: 60 KLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMA 119
Query: 474 LKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEA 533
L+++ K ++ + + + I K+ +++NI V A
Sbjct: 120 QALEKLFMQKLSQMPQEEQVVGVKERI----------KKGTQQNI----------AVSSA 159
Query: 534 REPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLM 593
+E S +F + +P K + P L +++ N + + +K
Sbjct: 160 KEKSSPSATEKVFKQQEIPSVFP---KTSISP--LNVVQGASVNSSSQTAAQVTKGVK-- 212
Query: 594 FRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSK 653
R A S V + E P + +A P +K + + P +
Sbjct: 213 -RKADTTTPATSAV------------KASSEFSPTFTEKSVALPPIKENMPKNVLPDSQQ 259
Query: 654 YMTPMQ-----QKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELP--DYYLTIKKPMDM 706
++ ++L E +K K+ + F + L +YY +K PMD+
Sbjct: 260 QYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDL 319
Query: 707 EKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKV 755
I+ M +Y+D D +MF N YN P+ + A +L V
Sbjct: 320 GTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368
Score = 53.1 bits (126), Expect = 2e-06
Identities = 26/76 (34%), Positives = 38/76 (50%)
Query: 692 ELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALV 751
+LPDYY IK PMD+ I+ + Y +EDF MF+N YN+P I A
Sbjct: 62 QLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQA 121
Query: 752 LHKVLLETRRDLEGDE 767
L K+ ++ + +E
Sbjct: 122 LEKLFMQKLSQMPQEE 137
Score = 51.2 bits (121), Expect = 8e-06
Identities = 67/330 (20%), Positives = 133/330 (40%), Gaps = 36/330 (10%)
Query: 219 DYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKK 278
+YY ++K P+DL TI +++ N YK + A D+ L+ N YN P +V A ++
Sbjct: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367
Query: 279 IF--YMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKR- 335
+F + K IE E + T + S+G+ ++ S+ R KR
Sbjct: 368 VFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDD----SEDERVKRL 423
Query: 336 AVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRS 395
A +L A+ LQ S+ + E + E + + + +
Sbjct: 424 AKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRLKEK 483
Query: 396 CRNNQGQLIAEPFYHLPSK----KKYPDYYQQIKMPISLQQ------------IRTKLKN 439
+ NQ + + F L S+ K +Y ++ ++ +++ + I+++ +
Sbjct: 484 SKRNQPKKRKQQFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPS 543
Query: 440 QEYETLDHLECDLNLMFENAKR--YNVPNSAIYKRVLK---------LQQVMQAKKKELA 488
D +E D + + R ++ + KR LK +++ KK+EL
Sbjct: 544 LSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQELE 603
Query: 489 RRDDIEDGDSMISSATSDTGSAKRKSKKNI 518
+R + D ++ ++S T S K + K +
Sbjct: 604 KR--LLDVNNQLNSRKRQTKSDKTQPSKAV 631
Score = 47.4 bits (111), Expect = 1e-04
Identities = 23/62 (37%), Positives = 34/62 (54%)
Query: 83 DYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWD 142
+YY+VV P+DL I++K+ +EY D AD +L+F N Y PD A L D
Sbjct: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367
Query: 143 LY 144
++
Sbjct: 368 VF 369
Score = 44.3 bits (103), Expect = 0.001
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 4/111 (3%)
Query: 82 PDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLW 141
PDYY ++ P+DL I+++L+ + Y + DF +F+N Y KP A L
Sbjct: 64 PDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALE 123
Query: 142 DLYLRTRNEFVQKGE--ADDEDDDEDGQDN--QGTVTEGSSPAYLKEILEQ 188
L+++ ++ Q+ + E + Q N + E SSP+ +++ +Q
Sbjct: 124 KLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQ 174
Score = 43.5 bits (101), Expect = 0.002
Identities = 37/186 (19%), Positives = 74/186 (39%), Gaps = 3/186 (1%)
Query: 557 DYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEK 616
+YY ++ PMDL I+ + N +Y D++LMF N YN +V A +L+
Sbjct: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367
Query: 617 LLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKR 676
+ + ++ P+ + M +K + + + ++ + K
Sbjct: 368 VFETHFSKI-PIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERVKRLAKL 426
Query: 677 GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNAC 736
+L A+ +L S++P L KK ++ + + N ++ M E M
Sbjct: 427 QEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQ--MRLKEKS 484
Query: 737 TYNEPE 742
N+P+
Sbjct: 485 KRNQPK 490
>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 93.6 bits (231), Expect = 1e-18
Identities = 77/311 (24%), Positives = 130/311 (41%), Gaps = 43/311 (13%)
Query: 214 KVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDA 273
K+Q PDYY IIK P+DL TI +R++N Y +D + + N YN+PG + A
Sbjct: 60 KLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMA 119
Query: 274 NSIKKIFYMKKAEIEHHEM---AKSSLRMRTPSNLA---AARLTGPSHSKGSLGEERNPT 327
+++K+F K +++ E K ++ T N+A A + PS ++ ++ P+
Sbjct: 120 QALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQQEIPS 179
Query: 328 ---SKYYRNKRAVQGGRLSAITMA---LQYGSESEEDAALAAARYEEGESEAESITSFMD 381
VQG +++ + + G + + D A + SE +
Sbjct: 180 VFPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKS 239
Query: 382 VSNP-------------FYQLYDTV---------RSCRNNQGQLIAE-------PFYHLP 412
V+ P Q Y+ V R C +++A+ PFY+
Sbjct: 240 VALPPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPV 299
Query: 413 SKKK--YPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIY 470
+YY +K P+ L I+ K+ NQEY+ D+ LMF N +YN P+ +
Sbjct: 300 DVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVV 359
Query: 471 KRVLKLQQVMQ 481
LQ V +
Sbjct: 360 TMARMLQDVFE 370
Score = 62.0 bits (149), Expect = 4e-09
Identities = 75/349 (21%), Positives = 129/349 (36%), Gaps = 47/349 (13%)
Query: 414 KKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRV 473
K + PDYY IK P+ L I+ +L+N+ Y D N MF N YN P I
Sbjct: 60 KLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMA 119
Query: 474 LKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEA 533
L+++ K ++ + + + I K+ +++NI V A
Sbjct: 120 QALEKLFMQKLSQMPQEEQVVGVKERI----------KKGTQQNI----------AVSSA 159
Query: 534 REPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLM 593
+E S +F + +P K + P L +++ N + + +K
Sbjct: 160 KEKSSPSATEKVFKQQEIPSVFP---KTSISP--LNVVQGASVNSSSQTAAQVTKGVK-- 212
Query: 594 FRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSK 653
R A S V + E P + +A P +K + + P +
Sbjct: 213 -RKADTTTPATSAV------------KASSEFSPTFTEKSVALPPIKENMPKNVLPDSQQ 259
Query: 654 YMTPMQ-----QKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELP--DYYLTIKKPMDM 706
++ ++L E +K K+ + F + L +YY +K PMD+
Sbjct: 260 QYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDL 319
Query: 707 EKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKV 755
I+ M +Y+D D +MF N YN P+ + A +L V
Sbjct: 320 GTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368
Score = 53.1 bits (126), Expect = 2e-06
Identities = 26/76 (34%), Positives = 38/76 (50%)
Query: 692 ELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALV 751
+LPDYY IK PMD+ I+ + Y +EDF MF+N YN+P I A
Sbjct: 62 QLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQA 121
Query: 752 LHKVLLETRRDLEGDE 767
L K+ ++ + +E
Sbjct: 122 LEKLFMQKLSQMPQEE 137
Score = 51.2 bits (121), Expect = 8e-06
Identities = 67/330 (20%), Positives = 133/330 (40%), Gaps = 36/330 (10%)
Query: 219 DYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKK 278
+YY ++K P+DL TI +++ N YK + A D+ L+ N YN P +V A ++
Sbjct: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367
Query: 279 IF--YMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKR- 335
+F + K IE E + T + S+G+ ++ S+ R KR
Sbjct: 368 VFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDD----SEDERVKRL 423
Query: 336 AVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRS 395
A +L A+ LQ S+ + E + E + + + +
Sbjct: 424 AKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRLKEK 483
Query: 396 CRNNQGQLIAEPFYHLPSK----KKYPDYYQQIKMPISLQQ------------IRTKLKN 439
+ NQ + + F L S+ K +Y ++ ++ +++ + I+++ +
Sbjct: 484 SKRNQPKKRKQQFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPS 543
Query: 440 QEYETLDHLECDLNLMFENAKR--YNVPNSAIYKRVLK---------LQQVMQAKKKELA 488
D +E D + + R ++ + KR LK +++ KK+EL
Sbjct: 544 LSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQELE 603
Query: 489 RRDDIEDGDSMISSATSDTGSAKRKSKKNI 518
+R + D ++ ++S T S K + K +
Sbjct: 604 KR--LLDVNNQLNSRKRQTKSDKTQPSKAV 631
Score = 47.4 bits (111), Expect = 1e-04
Identities = 23/62 (37%), Positives = 34/62 (54%)
Query: 83 DYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWD 142
+YY+VV P+DL I++K+ +EY D AD +L+F N Y PD A L D
Sbjct: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367
Query: 143 LY 144
++
Sbjct: 368 VF 369
Score = 44.3 bits (103), Expect = 0.001
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 4/111 (3%)
Query: 82 PDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLW 141
PDYY ++ P+DL I+++L+ + Y + DF +F+N Y KP A L
Sbjct: 64 PDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALE 123
Query: 142 DLYLRTRNEFVQKGE--ADDEDDDEDGQDN--QGTVTEGSSPAYLKEILEQ 188
L+++ ++ Q+ + E + Q N + E SSP+ +++ +Q
Sbjct: 124 KLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQ 174
Score = 43.5 bits (101), Expect = 0.002
Identities = 37/186 (19%), Positives = 74/186 (39%), Gaps = 3/186 (1%)
Query: 557 DYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEK 616
+YY ++ PMDL I+ + N +Y D++LMF N YN +V A +L+
Sbjct: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367
Query: 617 LLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKR 676
+ + ++ P+ + M +K + + + ++ + K
Sbjct: 368 VFETHFSKI-PIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERVKRLAKL 426
Query: 677 GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNAC 736
+L A+ +L S++P L KK ++ + + N ++ M E M
Sbjct: 427 QEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQ--MRLKEKS 484
Query: 737 TYNEPE 742
N+P+
Sbjct: 485 KRNQPK 490
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 89.7 bits (221), Expect = 2e-17
Identities = 50/171 (29%), Positives = 93/171 (54%), Gaps = 24/171 (14%)
Query: 619 KEKRKELGPLPDDDDMASPKLKLSRKSG--ISPKKSKYMTPMQQKLNEVYEAVKNYTDK- 675
+++R+ + P +D+ K + R +SP K + +++N + + V NY D+
Sbjct: 1346 RKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNPPK----LTKQMNAIIDTVINYKDRC 1401
Query: 676 -----------------RGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKY 718
GR+LS +F++LPSR ELP+YY I+KP+D +KI+ + +KY
Sbjct: 1402 NVEKVPSNSQLEIEGNSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKY 1461
Query: 719 QDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 769
+ + + +D +++ +NA T+N S IY+D++VL V R+ + +E+S
Sbjct: 1462 RSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEES 1512
Score = 86.3 bits (212), Expect = 2e-16
Identities = 44/159 (27%), Positives = 91/159 (57%), Gaps = 6/159 (3%)
Query: 398 NNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFE 457
N+ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ +++N +Y +L LE D+ L+
Sbjct: 1417 NSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCH 1476
Query: 458 NAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKN 517
NA+ +N+ S IY+ + LQ V ++ ++++A+ ++ ED S + + +S+
Sbjct: 1477 NAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESED-----ESNEEEEEEDEEESESE 1531
Query: 518 IRKQRMKILFNVVLE-AREPGSGRRLCDLFMVKPSKKDY 555
+ ++KI N + R+ G G++ + KP D+
Sbjct: 1532 AKSVKVKIKLNKKDDKGRDKGKGKKRPNRGKAKPVVSDF 1570
Score = 86.3 bits (212), Expect = 2e-16
Identities = 38/94 (40%), Positives = 65/94 (69%)
Query: 198 NPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAK 257
N SGR +SE+F +LPS+ + P+YY +I++P+D K I +RI+N Y+S+ + KD+ LL
Sbjct: 1417 NSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCH 1476
Query: 258 NAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHE 291
NA+T+N GSQ+++D+ ++ +F + +I E
Sbjct: 1477 NAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEE 1510
Score = 85.1 bits (209), Expect = 5e-16
Identities = 40/110 (36%), Positives = 69/110 (62%)
Query: 524 KILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGE 583
K+ N LE SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN KY
Sbjct: 1405 KVPSNSQLEIEGNSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSL 1464
Query: 584 EGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDD 633
+ +D+ L+ NA+ +N EGSQ+Y D+ +L+ + K R+++ + +D
Sbjct: 1465 GDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESED 1514
Score = 72.8 bits (177), Expect = 2e-12
Identities = 31/109 (28%), Positives = 67/109 (61%)
Query: 62 DEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFN 121
+ GR L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y + L D LL +
Sbjct: 1417 NSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCH 1476
Query: 122 NAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQ 170
NA+++ S Y+ + L ++ R + ++ E++DE ++E+ ++++
Sbjct: 1477 NAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEEDE 1525
Score = 47.8 bits (112), Expect = 9e-05
Identities = 28/120 (23%), Positives = 58/120 (48%), Gaps = 9/120 (7%)
Query: 817 KPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIR 876
+ P+ F I++ + N++YR L ++ + + A+ N S+IYED++ LQ F R
Sbjct: 1444 RKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSAR 1503
Query: 877 DELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSG 936
++ K E + + + E+E +E+ E + K+K + K++ + + G
Sbjct: 1504 QKIAKEEE---------SEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKG 1554
Score = 40.4 bits (93), Expect = 0.014
Identities = 34/118 (28%), Positives = 49/118 (41%), Gaps = 10/118 (8%)
Query: 1386 GLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQ-GVAPMVGTPA 1444
G+ + P+DG+ G ++ +H G + P PG+ PP M+Q M P+
Sbjct: 69 GMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMG--PPQSPMDQHSQGYMSPHPS 126
Query: 1445 PGGSP--YGQQVGVLGPPGQQAPPPYPGP-HPAGPPVIQQPTTPMFVAPPPKTQRLLH 1499
P G+P + GP Q PP PG P P + QP P P + LH
Sbjct: 127 PLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNR----GPSPFSPVQLH 180
Score = 35.8 bits (81), Expect = 0.34
Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 2/76 (2%)
Query: 1424 PGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAP-PPYPGPHPAGP-PVIQQ 1481
P P P + + PAPGG P PP P P P P P P PV+Q
Sbjct: 262 PSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAAAVPGPSVPQPAPGQPSPVLQL 321
Query: 1482 PTTPMFVAPPPKTQRL 1497
++P K Q L
Sbjct: 322 QQKQSRISPIQKPQGL 337
Score = 32.7 bits (73), Expect = 2.9
Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 20/72 (27%)
Query: 1385 PGLPPLQGPVDGLVSMGSMQPLHP---------------GGPPPHHLPPGVPG--LPGIP 1427
PG+ P Q P+D S G M P HP GGP P +PP PG +PG P
Sbjct: 104 PGMGPPQSPMDQH-SQGYMSP-HPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDP 161
Query: 1428 PP-GVMNQGVAP 1438
N+G +P
Sbjct: 162 QAMSQPNRGPSP 173
>gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens]
Length = 1872
Score = 84.0 bits (206), Expect = 1e-15
Identities = 63/229 (27%), Positives = 95/229 (41%), Gaps = 45/229 (19%)
Query: 546 FMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGS 605
F + K DYYKII PMDL+ + N+R Y E E ++L+ +N+ YN
Sbjct: 1405 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKH 1464
Query: 606 QVYNDAHILEKLLKEKRKE-----------LGPLPDDDDMASPKLKL----SRKSGISPK 650
+ + + L EK KE + PL DDDD + L ++K P
Sbjct: 1465 SLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPD 1524
Query: 651 KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIR 710
+ P+ +K +PDYY I PMD+E IR
Sbjct: 1525 SWPFHHPVNKKF------------------------------VPDYYKVIVNPMDLETIR 1554
Query: 711 SHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET 759
++ +KYQ +S ++D ++ N+ YN PES K A + V +T
Sbjct: 1555 KNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQT 1603
Score = 77.0 bits (188), Expect = 1e-13
Identities = 66/234 (28%), Positives = 106/234 (45%), Gaps = 34/234 (14%)
Query: 383 SNPFYQLYDTVRSCRNNQGQLIAEPFYHLP-SKKKYPDYYQQIKMPISLQQIRTKLKNQE 441
++P L + S N+ L +H P + K DYY+ I P+ LQ +R ++ +
Sbjct: 1379 TDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRL 1438
Query: 442 YETLDHLECDLNLMFENAKRYNVPNSA---IYKRVLKL-QQVMQAKKKELARRDD----- 492
Y + + L L+ +N+ YN P + I + +L L + ++ K+ +LAR +
Sbjct: 1439 YPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPL 1498
Query: 493 IEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSK 552
++D D + S D NI Q+M + P S F +K
Sbjct: 1499 LDDDDQVAFSFILD----------NIVTQKMMAV---------PDSWP-----FHHPVNK 1534
Query: 553 KDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQ 606
K PDYYK+I+ PMDL+ I NI KY E ++D+ L+ N+ YN SQ
Sbjct: 1535 KFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1588
Score = 70.9 bits (172), Expect = 9e-12
Identities = 59/265 (22%), Positives = 108/265 (40%), Gaps = 21/265 (7%)
Query: 26 VSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYY 85
++ P S RRR + T+ ++ + N +RD + F + DYY
Sbjct: 1367 LNRPHKSIHRRRTDPMVTLS--SILESIINDMRDLPNTYP------FHTPVNAKVVKDYY 1418
Query: 86 EVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYL 145
+++++P+DL +++ ++ Y +L+ N+ +Y P + + + DL
Sbjct: 1419 KIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCD 1478
Query: 146 RTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLIS 205
E ED + + + IL+ ++ ++A S
Sbjct: 1479 EKLKE--------KEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWP--- 1527
Query: 206 ELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEP 265
F +K PDYY +I P+DL+TI + I Y+S + D++L+ N+ YN P
Sbjct: 1528 --FHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGP 1585
Query: 266 GSQVFKDANSIKKIFYMKKAEIEHH 290
SQ K A I + Y E + H
Sbjct: 1586 ESQYTKTAQEIVNVCYQTLTEYDEH 1610
Score = 53.1 bits (126), Expect = 2e-06
Identities = 25/73 (34%), Positives = 41/73 (56%)
Query: 407 PFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPN 466
PF+H +KK PDYY+ I P+ L+ IR + +Y++ + D+NL+ N+ +YN P
Sbjct: 1527 PFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPE 1586
Query: 467 SAIYKRVLKLQQV 479
S K ++ V
Sbjct: 1587 SQYTKTAQEIVNV 1599
>gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens]
Length = 1893
Score = 84.0 bits (206), Expect = 1e-15
Identities = 63/229 (27%), Positives = 95/229 (41%), Gaps = 45/229 (19%)
Query: 546 FMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGS 605
F + K DYYKII PMDL+ + N+R Y E E ++L+ +N+ YN
Sbjct: 1426 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKH 1485
Query: 606 QVYNDAHILEKLLKEKRKE-----------LGPLPDDDDMASPKLKL----SRKSGISPK 650
+ + + L EK KE + PL DDDD + L ++K P
Sbjct: 1486 SLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPD 1545
Query: 651 KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIR 710
+ P+ +K +PDYY I PMD+E IR
Sbjct: 1546 SWPFHHPVNKKF------------------------------VPDYYKVIVNPMDLETIR 1575
Query: 711 SHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET 759
++ +KYQ +S ++D ++ N+ YN PES K A + V +T
Sbjct: 1576 KNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQT 1624
Score = 77.0 bits (188), Expect = 1e-13
Identities = 66/234 (28%), Positives = 106/234 (45%), Gaps = 34/234 (14%)
Query: 383 SNPFYQLYDTVRSCRNNQGQLIAEPFYHLP-SKKKYPDYYQQIKMPISLQQIRTKLKNQE 441
++P L + S N+ L +H P + K DYY+ I P+ LQ +R ++ +
Sbjct: 1400 TDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRL 1459
Query: 442 YETLDHLECDLNLMFENAKRYNVPNSA---IYKRVLKL-QQVMQAKKKELARRDD----- 492
Y + + L L+ +N+ YN P + I + +L L + ++ K+ +LAR +
Sbjct: 1460 YPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPL 1519
Query: 493 IEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSK 552
++D D + S D NI Q+M + P S F +K
Sbjct: 1520 LDDDDQVAFSFILD----------NIVTQKMMAV---------PDSWP-----FHHPVNK 1555
Query: 553 KDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQ 606
K PDYYK+I+ PMDL+ I NI KY E ++D+ L+ N+ YN SQ
Sbjct: 1556 KFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1609
Score = 70.9 bits (172), Expect = 9e-12
Identities = 59/265 (22%), Positives = 108/265 (40%), Gaps = 21/265 (7%)
Query: 26 VSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYY 85
++ P S RRR + T+ ++ + N +RD + F + DYY
Sbjct: 1388 LNRPHKSIHRRRTDPMVTLS--SILESIINDMRDLPNTYP------FHTPVNAKVVKDYY 1439
Query: 86 EVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYL 145
+++++P+DL +++ ++ Y +L+ N+ +Y P + + + DL
Sbjct: 1440 KIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCD 1499
Query: 146 RTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLIS 205
E ED + + + IL+ ++ ++A S
Sbjct: 1500 EKLKE--------KEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWP--- 1548
Query: 206 ELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEP 265
F +K PDYY +I P+DL+TI + I Y+S + D++L+ N+ YN P
Sbjct: 1549 --FHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGP 1606
Query: 266 GSQVFKDANSIKKIFYMKKAEIEHH 290
SQ K A I + Y E + H
Sbjct: 1607 ESQYTKTAQEIVNVCYQTLTEYDEH 1631
Score = 53.1 bits (126), Expect = 2e-06
Identities = 25/73 (34%), Positives = 41/73 (56%)
Query: 407 PFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPN 466
PF+H +KK PDYY+ I P+ L+ IR + +Y++ + D+NL+ N+ +YN P
Sbjct: 1548 PFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPE 1607
Query: 467 SAIYKRVLKLQQV 479
S K ++ V
Sbjct: 1608 SQYTKTAQEIVNV 1620
>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
Length = 2964
Score = 82.0 bits (201), Expect = 4e-15
Identities = 52/183 (28%), Positives = 79/183 (43%), Gaps = 24/183 (13%)
Query: 1117 EPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPR--------------------VGRIEK 1156
+PGC YF L +D+ L+ GDCV++ P + RIEK
Sbjct: 2642 QPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLLSHINRDKLDIFRIEK 2701
Query: 1157 VWVRDGAAYF-YGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKD 1215
+W + F +G + P ET H P++ FY E+F L E P+ ++G C VL
Sbjct: 2702 LWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLYT 2761
Query: 1216 FLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKE 1275
+ RP + E D+ +C+ R DK F + R +F K + P+K+
Sbjct: 2762 YCKGRPKGVKEQDVYICDYRL---DKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKKD 2818
Query: 1276 PSP 1278
SP
Sbjct: 2819 FSP 2821
Score = 64.7 bits (156), Expect = 7e-10
Identities = 32/99 (32%), Positives = 50/99 (50%)
Query: 52 ELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNL 111
E+ + I YKD + L + P ++ DYYE +S P+DL+ I++++ Y V
Sbjct: 2446 EICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEA 2505
Query: 112 LTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNE 150
AD +F NA+ YY SP + C+L Y R+E
Sbjct: 2506 FDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHE 2544
Score = 63.9 bits (154), Expect = 1e-09
Identities = 33/129 (25%), Positives = 72/129 (55%)
Query: 386 FYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETL 445
F ++ D + S +++ Q +A P +LP KKK DYY++I P+ L I ++ Y+T+
Sbjct: 2444 FKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTV 2503
Query: 446 DHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATS 505
+ + D+ +F NA++Y S + + V +L++ + E + + D G++ + +S
Sbjct: 2504 EAFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIVGETASEADSS 2563
Query: 506 DTGSAKRKS 514
+T +++++
Sbjct: 2564 ETSVSEKEN 2572
Score = 58.5 bits (140), Expect = 5e-08
Identities = 33/112 (29%), Positives = 60/112 (53%)
Query: 175 EGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIA 234
E + A L +I +++ + I+ + S + ++ LP K + DYY I +P+DL TI
Sbjct: 2433 EVARAARLAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIE 2492
Query: 235 QRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAE 286
++I G YK++ A D+ + +NA+ Y S V +D ++K +Y + E
Sbjct: 2493 KQILTGYYKTVEAFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHE 2544
Score = 53.9 bits (128), Expect = 1e-06
Identities = 29/114 (25%), Positives = 52/114 (45%)
Query: 658 MQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANK 717
+ Q E+ + + +Y D + L+A L LP + + DYY I P+D+ I ++
Sbjct: 2440 LAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGY 2499
Query: 718 YQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHV 771
Y+ +++ D + +F NA Y +S + +D L K R + D V
Sbjct: 2500 YKTVEAFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIV 2553
Score = 45.4 bits (106), Expect = 4e-04
Identities = 30/82 (36%), Positives = 35/82 (42%)
Query: 550 PSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYN 609
P KK DYY+ I +P+DL IE I Y E DM +FRNA Y S V
Sbjct: 2470 PPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEAFDADMLKVFRNAEKYYGRKSPVGR 2529
Query: 610 DAHILEKLLKEKRKELGPLPDD 631
D L K R E D+
Sbjct: 2530 DVCRLRKAYYNARHEASAQIDE 2551
Score = 42.0 bits (97), Expect = 0.005
Identities = 18/65 (27%), Positives = 34/65 (52%)
Query: 991 EVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKL 1050
E+F+ Y +P+ ++G C V+ + Y K P+ +++DV++C+ R F KI
Sbjct: 2735 ELFRVPLYEIIPLEAVVGTCCVLDLYTYCKGRPKGVKEQDVYICDYRLDKSAHLFYKIHR 2794
Query: 1051 WTMPI 1055
P+
Sbjct: 2795 NRYPV 2799
>gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo
sapiens]
Length = 1826
Score = 81.3 bits (199), Expect = 7e-15
Identities = 61/229 (26%), Positives = 95/229 (41%), Gaps = 45/229 (19%)
Query: 546 FMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGS 605
F + K DYYKII PMDL+ + N+R Y E E ++L+ +N+ YN
Sbjct: 1424 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKH 1483
Query: 606 QVYNDAHILEKLLKEKRKE-----------LGPLPDDDDMASPKLKL----SRKSGISPK 650
+ + + L EK KE + PL DDDD + L ++K P
Sbjct: 1484 SLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPD 1543
Query: 651 KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIR 710
+ P+ +K +PDYY I P+D+E IR
Sbjct: 1544 SWPFHHPVNKKF------------------------------VPDYYKMIVNPVDLETIR 1573
Query: 711 SHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET 759
++ +KYQ +S ++D ++ N+ YN PES K A + + +T
Sbjct: 1574 KNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICYQT 1622
Score = 73.6 bits (179), Expect = 1e-12
Identities = 65/234 (27%), Positives = 105/234 (44%), Gaps = 34/234 (14%)
Query: 383 SNPFYQLYDTVRSCRNNQGQLIAEPFYHLP-SKKKYPDYYQQIKMPISLQQIRTKLKNQE 441
++P L + S N+ L +H P + K DYY+ I P+ LQ +R ++
Sbjct: 1398 TDPMVTLSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCL 1457
Query: 442 YETLDHLECDLNLMFENAKRYNVPNSA---IYKRVLKL-QQVMQAKKKELARRDD----- 492
Y + + L L+ +N+ YN P + I + +L L + ++ K+ +LAR +
Sbjct: 1458 YPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPL 1517
Query: 493 IEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSK 552
++D D + S D NI Q+M + P S F +K
Sbjct: 1518 LDDDDQVAFSFILD----------NIVTQKMMAV---------PDSWP-----FHHPVNK 1553
Query: 553 KDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQ 606
K PDYYK+I+ P+DL+ I NI KY E ++D+ L+ N+ YN SQ
Sbjct: 1554 KFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1607
Score = 69.7 bits (169), Expect = 2e-11
Identities = 60/265 (22%), Positives = 108/265 (40%), Gaps = 21/265 (7%)
Query: 26 VSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYY 85
++ P S RRR + T+ ++ + N +RD + F + DYY
Sbjct: 1386 LNIPHKSIHRRRTDPMVTLS--SILESIINDMRDLPNTHP------FHTPVNAKVVKDYY 1437
Query: 86 EVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYL 145
+++++P+DL +++ ++ Y +L+ N+ +Y P + + + DL
Sbjct: 1438 KIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCD 1497
Query: 146 RTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLIS 205
E ED + + + IL+ ++ ++A S
Sbjct: 1498 EKLKE--------KEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWP--- 1546
Query: 206 ELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEP 265
F +K PDYY +I P+DL+TI + I Y+S + D++L+ N+ YN P
Sbjct: 1547 --FHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGP 1604
Query: 266 GSQVFKDANSIKKIFYMKKAEIEHH 290
SQ K A I I Y E + H
Sbjct: 1605 ESQYTKTAQEIVNICYQTITEYDEH 1629
Score = 54.3 bits (129), Expect = 9e-07
Identities = 24/73 (32%), Positives = 41/73 (56%)
Query: 407 PFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPN 466
PF+H +KK PDYY+ I P+ L+ IR + +Y++ + D+NL+ N+ +YN P
Sbjct: 1546 PFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPE 1605
Query: 467 SAIYKRVLKLQQV 479
S K ++ +
Sbjct: 1606 SQYTKTAQEIVNI 1618
>gi|16445438 bromodomain and WD repeat domain containing 1 isoform B
[Homo sapiens]
Length = 2269
Score = 74.7 bits (182), Expect = 7e-13
Identities = 59/232 (25%), Positives = 101/232 (43%), Gaps = 30/232 (12%)
Query: 417 YPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYK----- 471
YP Y + P L IR +L N+ Y L L ++ + NA+ +N P S I +
Sbjct: 1194 YPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKI 1253
Query: 472 -----RVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRK---SKKNIR---- 519
+ +K Q + +D ++ + + S T S +R+ KK+IR
Sbjct: 1254 TDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNY 1313
Query: 520 -----KQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHN 574
K++ K L N++ + + R+ DL +YPDY II PMD +
Sbjct: 1314 VESNWKKQCKELVNLIFQCEDSEPFRQPVDLV-------EYPDYRDIIDTPMDFGTVRET 1366
Query: 575 IRNDKYAGEEGMIEDMKLMFRNARHYN-EEGSQVYNDAHILEKLLKEKRKEL 625
+ Y +D++L+F NA+ Y + S++Y+ L L +EK K++
Sbjct: 1367 LDAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKI 1418
Score = 70.9 bits (172), Expect = 9e-12
Identities = 72/326 (22%), Positives = 127/326 (38%), Gaps = 58/326 (17%)
Query: 217 YPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSI 276
YP Y ++ P DL TI R+ N Y+ + A+ ++ + NA+T+NEP S + A S
Sbjct: 1194 YPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVI---ARSA 1250
Query: 277 KKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRA 336
KKI + ++ + +N++ T + + + + + K +R
Sbjct: 1251 KKI----------TDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRR 1300
Query: 337 VQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSC 396
V G+ S + A Y E + + ++ N +Q D
Sbjct: 1301 VHDGKKS-----------------IRATNYVESNWKKQC----KELVNLIFQCED----- 1334
Query: 397 RNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMF 456
+EPF +YPDY I P+ +R L Y++ D+ L+F
Sbjct: 1335 --------SEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIF 1386
Query: 457 ENAKRYNVPN--SAIYKRVLKLQQVMQAKKKELAR--------RDDIEDGDSMISSATSD 506
NAK Y PN S IY L+L + + K K+++ + +
Sbjct: 1387 SNAKAY-TPNKRSKIYSMTLRLSALFEEKMKKISSDFKIGQKFNEKLRRSQRFKQRQNCK 1445
Query: 507 TGSAKRKSKKNIRKQRMKILFNVVLE 532
S KS +N++ +R+K ++ E
Sbjct: 1446 GDSQPNKSIRNLKPKRLKSQTKIIPE 1471
Score = 65.1 bits (157), Expect = 5e-10
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 30/230 (13%)
Query: 82 PDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLW 141
P Y VV+ P DL I+ +L Y ++ L + + + +NA+++ +P+S ++A K+
Sbjct: 1195 PKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKIT 1254
Query: 142 DLYLR-------TRNEFVQKGEADDEDDDEDGQDNQGTVTEGSS---------------- 178
D L+ T + +DE + ED D+ T
Sbjct: 1255 DQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNYV 1314
Query: 179 PAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQ 238
+ K+ ++L+ I + SE F++ V+YPDY II P+D T+ + +
Sbjct: 1315 ESNWKKQCKELVNLIFQCED------SEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLD 1368
Query: 239 NGSYKSIHAMAKDIDLLAKNAKTYN-EPGSQVFKDANSIKKIFYMKKAEI 287
G+Y S KDI L+ NAK Y S+++ + +F K +I
Sbjct: 1369 AGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKI 1418
Score = 51.2 bits (121), Expect = 8e-06
Identities = 57/234 (24%), Positives = 87/234 (37%), Gaps = 28/234 (11%)
Query: 555 YPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAH-I 613
YP Y ++ P DL I + N Y ++ +++ + NAR +NE S + A I
Sbjct: 1194 YPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKI 1253
Query: 614 LEKLLK---------------EKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPM 658
++LLK + D DD PK R+ KKS T
Sbjct: 1254 TDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNY 1313
Query: 659 -----QQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHM 713
+++ E+ + D S F + E PDY I PMD +R +
Sbjct: 1314 VESNWKKQCKELVNLIFQCED------SEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETL 1367
Query: 714 MANKYQDIDSMVEDFVMMFNNACTYN-EPESLIYKDALVLHKVLLETRRDLEGD 766
A Y +D ++F+NA Y S IY L L + E + + D
Sbjct: 1368 DAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISSD 1421
Score = 41.6 bits (96), Expect = 0.006
Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 17/142 (11%)
Query: 18 DFDDGHHSVSTPGPSR-----KRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELF 72
D DD ++ G R K R +N + C EL N I +D E F
Sbjct: 1285 DLDDSDLPKTSSGRRRVHDGKKSIRATNYVESNWKKQCKELVNLIFQCEDS------EPF 1338
Query: 73 IRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSP 132
+ PDY +++ P+D +++ L YD D +L+F+NAK+Y +P
Sbjct: 1339 RQPVDLVEYPDYRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIFSNAKAY----TP 1394
Query: 133 EYKAACKLWDLYLRTRNEFVQK 154
++ K++ + LR F +K
Sbjct: 1395 NKRS--KIYSMTLRLSALFEEK 1414
>gi|16445436 bromodomain and WD repeat domain containing 1 isoform A
[Homo sapiens]
Length = 2320
Score = 74.7 bits (182), Expect = 7e-13
Identities = 59/232 (25%), Positives = 101/232 (43%), Gaps = 30/232 (12%)
Query: 417 YPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYK----- 471
YP Y + P L IR +L N+ Y L L ++ + NA+ +N P S I +
Sbjct: 1194 YPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKI 1253
Query: 472 -----RVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRK---SKKNIR---- 519
+ +K Q + +D ++ + + S T S +R+ KK+IR
Sbjct: 1254 TDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNY 1313
Query: 520 -----KQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHN 574
K++ K L N++ + + R+ DL +YPDY II PMD +
Sbjct: 1314 VESNWKKQCKELVNLIFQCEDSEPFRQPVDLV-------EYPDYRDIIDTPMDFGTVRET 1366
Query: 575 IRNDKYAGEEGMIEDMKLMFRNARHYN-EEGSQVYNDAHILEKLLKEKRKEL 625
+ Y +D++L+F NA+ Y + S++Y+ L L +EK K++
Sbjct: 1367 LDAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKI 1418
Score = 70.9 bits (172), Expect = 9e-12
Identities = 72/326 (22%), Positives = 127/326 (38%), Gaps = 58/326 (17%)
Query: 217 YPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSI 276
YP Y ++ P DL TI R+ N Y+ + A+ ++ + NA+T+NEP S + A S
Sbjct: 1194 YPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVI---ARSA 1250
Query: 277 KKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRA 336
KKI + ++ + +N++ T + + + + + K +R
Sbjct: 1251 KKI----------TDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRR 1300
Query: 337 VQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSC 396
V G+ S + A Y E + + ++ N +Q D
Sbjct: 1301 VHDGKKS-----------------IRATNYVESNWKKQC----KELVNLIFQCED----- 1334
Query: 397 RNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMF 456
+EPF +YPDY I P+ +R L Y++ D+ L+F
Sbjct: 1335 --------SEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIF 1386
Query: 457 ENAKRYNVPN--SAIYKRVLKLQQVMQAKKKELAR--------RDDIEDGDSMISSATSD 506
NAK Y PN S IY L+L + + K K+++ + +
Sbjct: 1387 SNAKAY-TPNKRSKIYSMTLRLSALFEEKMKKISSDFKIGQKFNEKLRRSQRFKQRQNCK 1445
Query: 507 TGSAKRKSKKNIRKQRMKILFNVVLE 532
S KS +N++ +R+K ++ E
Sbjct: 1446 GDSQPNKSIRNLKPKRLKSQTKIIPE 1471
Score = 65.1 bits (157), Expect = 5e-10
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 30/230 (13%)
Query: 82 PDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLW 141
P Y VV+ P DL I+ +L Y ++ L + + + +NA+++ +P+S ++A K+
Sbjct: 1195 PKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKIT 1254
Query: 142 DLYLR-------TRNEFVQKGEADDEDDDEDGQDNQGTVTEGSS---------------- 178
D L+ T + +DE + ED D+ T
Sbjct: 1255 DQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNYV 1314
Query: 179 PAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQ 238
+ K+ ++L+ I + SE F++ V+YPDY II P+D T+ + +
Sbjct: 1315 ESNWKKQCKELVNLIFQCED------SEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLD 1368
Query: 239 NGSYKSIHAMAKDIDLLAKNAKTYN-EPGSQVFKDANSIKKIFYMKKAEI 287
G+Y S KDI L+ NAK Y S+++ + +F K +I
Sbjct: 1369 AGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKI 1418
Score = 51.2 bits (121), Expect = 8e-06
Identities = 57/234 (24%), Positives = 87/234 (37%), Gaps = 28/234 (11%)
Query: 555 YPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAH-I 613
YP Y ++ P DL I + N Y ++ +++ + NAR +NE S + A I
Sbjct: 1194 YPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKI 1253
Query: 614 LEKLLK---------------EKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPM 658
++LLK + D DD PK R+ KKS T
Sbjct: 1254 TDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNY 1313
Query: 659 -----QQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHM 713
+++ E+ + D S F + E PDY I PMD +R +
Sbjct: 1314 VESNWKKQCKELVNLIFQCED------SEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETL 1367
Query: 714 MANKYQDIDSMVEDFVMMFNNACTYN-EPESLIYKDALVLHKVLLETRRDLEGD 766
A Y +D ++F+NA Y S IY L L + E + + D
Sbjct: 1368 DAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISSD 1421
Score = 41.6 bits (96), Expect = 0.006
Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 17/142 (11%)
Query: 18 DFDDGHHSVSTPGPSR-----KRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELF 72
D DD ++ G R K R +N + C EL N I +D E F
Sbjct: 1285 DLDDSDLPKTSSGRRRVHDGKKSIRATNYVESNWKKQCKELVNLIFQCEDS------EPF 1338
Query: 73 IRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSP 132
+ PDY +++ P+D +++ L YD D +L+F+NAK+Y +P
Sbjct: 1339 RQPVDLVEYPDYRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIFSNAKAY----TP 1394
Query: 133 EYKAACKLWDLYLRTRNEFVQK 154
++ K++ + LR F +K
Sbjct: 1395 NKRS--KIYSMTLRLSALFEEK 1414
>gi|34996489 pleckstrin homology domain interacting protein [Homo
sapiens]
Length = 1821
Score = 73.9 bits (180), Expect = 1e-12
Identities = 60/223 (26%), Positives = 103/223 (46%), Gaps = 35/223 (15%)
Query: 68 LCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYY 127
+ F+ + P Y VV+ P DL I+Q+L+ Y V+ L + + + +N +++
Sbjct: 1180 IASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFN 1239
Query: 128 KPDSPEYKAACKLWDLYLR------------TRNEFVQKGEADDEDDDEDGQDNQGTVTE 175
+P SP K+A + DL L N +K +D ED+++D D GT T
Sbjct: 1240 EPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEDEEKDA-DVPGTSTR 1298
Query: 176 ------------GSSPAY----LKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPD 219
+ +Y K+ E+LL I + SE F++ ++YPD
Sbjct: 1299 KRKDHQPRRRLRNRAQSYDIQAWKKQCEELLNLIFQCED------SEPFRQPVDLLEYPD 1352
Query: 220 YYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTY 262
Y II P+D T+ + ++ G+Y+S + KD+ L+ N+K Y
Sbjct: 1353 YRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAY 1395
Score = 61.2 bits (147), Expect = 7e-09
Identities = 55/244 (22%), Positives = 99/244 (40%), Gaps = 34/244 (13%)
Query: 404 IAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYN 463
IA F + YP Y + P L I+ +L+N+ Y + L ++ + N + +N
Sbjct: 1180 IASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFN 1239
Query: 464 VPNSAIYKRVLKLQQVM-----------------QAKKKELARRDDIE-DGDSMISSATS 505
P S I K + ++ KKK L+ +D E D D +S
Sbjct: 1240 EPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEDEEKDADVPGTSTRK 1299
Query: 506 DTGSAKRKSKKN--------IRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPD 557
R+ +N K++ + L N++ + + R+ DL +YPD
Sbjct: 1300 RKDHQPRRRLRNRAQSYDIQAWKKQCEELLNLIFQCEDSEPFRQPVDLL-------EYPD 1352
Query: 558 YYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYN-EEGSQVYNDAHILEK 616
Y II PMD + + Y + +D++L+F N++ Y + S++Y+ + L
Sbjct: 1353 YRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLRLSA 1412
Query: 617 LLKE 620
+E
Sbjct: 1413 FFEE 1416
Score = 54.7 bits (130), Expect = 7e-07
Identities = 55/231 (23%), Positives = 92/231 (39%), Gaps = 20/231 (8%)
Query: 542 LCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYN 601
+ F+ + YP Y ++ P DL I+ + N Y ++ +++ + N R +N
Sbjct: 1180 IASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFN 1239
Query: 602 EEGSQVYNDAHILEKLLKEKRKE---LGPLPDDDDMASPKLKLSRKS-------GISPKK 651
E GS + A + LL K+ +P + M L S G S +K
Sbjct: 1240 EPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEDEEKDADVPGTSTRK 1299
Query: 652 SKYMTPMQQKLNEVYE-AVKNYTDKRGRRLSAIF-------LRLP-SRSELPDYYLTIKK 702
K P ++ N ++ + + L+ IF R P E PDY I
Sbjct: 1300 RKDHQPRRRLRNRAQSYDIQAWKKQCEELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDT 1359
Query: 703 PMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYN-EPESLIYKDALVL 752
PMD +R + A Y+ + +D ++F+N+ Y S IY +L L
Sbjct: 1360 PMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLRL 1410
Score = 52.8 bits (125), Expect = 3e-06
Identities = 21/60 (35%), Positives = 36/60 (60%)
Query: 217 YPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSI 276
YP Y ++ P DL TI QR++N Y+ + ++ ++ + N +T+NEPGS + K A +
Sbjct: 1193 YPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFV 1252
Score = 45.4 bits (106), Expect = 4e-04
Identities = 39/122 (31%), Positives = 52/122 (42%), Gaps = 18/122 (14%)
Query: 405 AEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYN- 463
+EPF +YPDY I P+ +R L+ YE+ L D+ L+F N+K Y
Sbjct: 1338 SEPFRQPVDLLEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTP 1397
Query: 464 VPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKN-IRKQR 522
S IY L+L + ISS SD SA R K+N I K+R
Sbjct: 1398 SKRSRIYSMSLRLSAFF----------------EEHISSVLSDYKSALRFHKRNTITKRR 1441
Query: 523 MK 524
K
Sbjct: 1442 KK 1443
Score = 34.7 bits (78), Expect = 0.75
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 694 PDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLH 753
P Y + P D+ I+ + Y+ + S++ + + +N T+NEP S I K A +
Sbjct: 1194 PMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVT 1253
Query: 754 KVLLETRRD 762
+LL +D
Sbjct: 1254 DLLLHFIKD 1262
Score = 31.2 bits (69), Expect = 8.3
Identities = 26/117 (22%), Positives = 44/117 (37%), Gaps = 5/117 (4%)
Query: 819 PLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIK-IRD 877
P I++ +EN YRR+ + + R N S I + A + + I+D
Sbjct: 1203 PTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVTDLLLHFIKD 1262
Query: 878 ELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDS 934
+ C N + P + K + +D E E K+ K K + +R S
Sbjct: 1263 QTCYN----IIPLYNSMKKKVLSDSEDEEKDADVPGTSTRKRKDHQPRRRLRNRAQS 1315
>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
Length = 744
Score = 66.6 bits (161), Expect = 2e-10
Identities = 47/122 (38%), Positives = 55/122 (45%), Gaps = 28/122 (22%)
Query: 1377 EGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGV 1436
+G+ G PPG+P + GP P GPP P G PGLPG PPG G
Sbjct: 491 QGLQG--PPGIPGIGGPSG------------PIGPPGIPGPKGEPGLPG--PPGFPGIGK 534
Query: 1437 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPG-PHPAGPPVIQQPTTPMFVAPPPKTQ 1495
+ G P G P G LGP GQ P PG P P GPP + PT PPP+ +
Sbjct: 535 PGVAGLHGPPGKP-----GALGPQGQPGLPGPPGPPGPPGPPAVMPPT------PPPQGE 583
Query: 1496 RL 1497
L
Sbjct: 584 YL 585
Score = 57.4 bits (137), Expect = 1e-07
Identities = 39/90 (43%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 1384 PPGLPPLQGPVDGLVSMGSMQPLHPG--GPPPHHLPPGVPGLPGIPPPGVMN-QGVAPMV 1440
P GLP QG G P PG GPP H PPG GLPG+ PGV G +
Sbjct: 227 PKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPL 286
Query: 1441 GTPAPGGSPYGQQVGVLGPPGQQAPPPYPG 1470
G P G P Q G +G PG Q PP PG
Sbjct: 287 GKPGAPGEPGPQ--GPIGVPGVQGPPGIPG 314
Score = 51.6 bits (122), Expect = 6e-06
Identities = 48/148 (32%), Positives = 60/148 (40%), Gaps = 40/148 (27%)
Query: 1380 MGGYP--PGLPPLQGPVDGLVSMGSMQP------LHPGGPPPHHLPPGVPGLPGIP---- 1427
+GG P PGLP + GP+ ++G P + P GPP PG+ G PG P
Sbjct: 385 IGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLG 444
Query: 1428 ---PPGVMN-------QGVAPMVGTPAPGGSPYGQQVGVLGPPGQ---------QAPPPY 1468
PPG+ +G A G P G P G+LGP G+ Q PP
Sbjct: 445 EVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVP-----GLLGPKGEPGIPGDQGLQGPPGI 499
Query: 1469 PG----PHPAGPPVIQQPTTPMFVAPPP 1492
PG P GPP I P + PP
Sbjct: 500 PGIGGPSGPIGPPGIPGPKGEPGLPGPP 527
Score = 51.2 bits (121), Expect = 8e-06
Identities = 39/111 (35%), Positives = 46/111 (41%), Gaps = 3/111 (2%)
Query: 1385 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1444
PG P G V G P+ P G PG+PG+PG+ P G+ G
Sbjct: 437 PGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGP-KGEPGIPGDQGLQG 495
Query: 1445 PGGSP-YGQQVGVLGPPGQQAPPPYPG-PHPAGPPVIQQPTTPMFVAPPPK 1493
P G P G G +GPPG P PG P P G P I +P PP K
Sbjct: 496 PPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGK 546
Score = 48.1 bits (113), Expect = 7e-05
Identities = 39/117 (33%), Positives = 47/117 (40%), Gaps = 11/117 (9%)
Query: 1385 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMN-------QGVA 1437
PG P G +G + P G P PPG GLPGI PG +G
Sbjct: 166 PGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDR 225
Query: 1438 PMVGTPAPGG--SPYGQQ-VGVLGPPGQQAPPPYPG-PHPAGPPVIQQPTTPMFVAP 1490
G P P G P G + G+ G PG + PP G P P G P + +P F P
Sbjct: 226 GPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGP 282
Score = 48.1 bits (113), Expect = 7e-05
Identities = 37/100 (37%), Positives = 42/100 (42%), Gaps = 21/100 (21%)
Query: 1384 PPGLPPL-------------QGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPG 1430
PPGLP + G V G ++G P G P PPG PGLPGIP P
Sbjct: 344 PPGLPGIGKPGFPGPKGDRGMGGVPG--ALGPRGEKGPIGAPGIGGPPGEPGLPGIPGP- 400
Query: 1431 VMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPG 1470
G +G P P G G VG GPPG + P G
Sbjct: 401 ---MGPPGAIGFPGPKGE--GGIVGPQGPPGPKGEPGLQG 435
Score = 47.0 bits (110), Expect = 1e-04
Identities = 42/109 (38%), Positives = 48/109 (44%), Gaps = 15/109 (13%)
Query: 1384 PPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIP-------PPGVMNQGV 1436
PPG+ GPV GL +G +P G P P P G PG PG P PGV
Sbjct: 256 PPGMHGPPGPV-GLPGVG--KPGVTGFPGPQG-PLGKPGAPGEPGPQGPIGVPGVQGPPG 311
Query: 1437 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTP 1485
P +G P G P Q G G G+Q P PG P G P I +P P
Sbjct: 312 IPGIGKPGQDGIP--GQPGFPGGKGEQGLPGLPG--PPGLPGIGKPGFP 356
Score = 46.6 bits (109), Expect = 2e-04
Identities = 43/123 (34%), Positives = 50/123 (40%), Gaps = 26/123 (21%)
Query: 1384 PPGLPPLQGPVDGLVSMGSMQPLHPG-----GPPPHHLPPGVPGLPGI------------ 1426
P G+P QGP G +P PG GP P G+PG G+
Sbjct: 189 PMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMP 248
Query: 1427 PPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAP------PPYPGPH-PAGPPVI 1479
PGV +G M G P P G P + GV G PG Q P P PGP P G P +
Sbjct: 249 GAPGV--KGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGV 306
Query: 1480 QQP 1482
Q P
Sbjct: 307 QGP 309
Score = 46.2 bits (108), Expect = 2e-04
Identities = 42/131 (32%), Positives = 50/131 (38%), Gaps = 43/131 (32%)
Query: 1386 GLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVP-----------------------G 1422
G P QGP+ + G P P G P PPG+P G
Sbjct: 278 GFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQG 337
Query: 1423 LPGIP-PPGVMNQGVAPMVGTPAPGG-----------SPYGQQVGVLGPPGQQAPPPYPG 1470
LPG+P PPG+ G G P P G P G++ G +G PG PP PG
Sbjct: 338 LPGLPGPPGLPGIG---KPGFPGPKGDRGMGGVPGALGPRGEK-GPIGAPGIGGPPGEPG 393
Query: 1471 ----PHPAGPP 1477
P P GPP
Sbjct: 394 LPGIPGPMGPP 404
Score = 43.5 bits (101), Expect = 0.002
Identities = 37/107 (34%), Positives = 42/107 (39%), Gaps = 22/107 (20%)
Query: 1410 GPPPHHLPPGVPGLPGIPP---------------PGVMNQGVAPMVGTPAPGGSPYGQ-- 1452
GP P G PG PG+P PGV G+ M G P G P +
Sbjct: 121 GPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGE 180
Query: 1453 --QVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPP-PKTQR 1496
Q G +GP G P PGPH G P I +P P P PK R
Sbjct: 181 IGQKGEIGPMGIPGPQGPPGPH--GLPGIGKPGGPGLPGQPGPKGDR 225
Score = 39.3 bits (90), Expect = 0.031
Identities = 45/128 (35%), Positives = 53/128 (41%), Gaps = 14/128 (10%)
Query: 1384 PPGLPPLQGPVDGLVSMGS--MQPLH-PGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMV 1440
P G P L GP G +G + LH P G P P G PGLPG P P A M
Sbjct: 517 PKGEPGLPGP-PGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMP 575
Query: 1441 GTPAPGGSPYGQQVGVLGPPGQQAPPPY-------PGPHPAGPPVIQQPTTPM-FVAPPP 1492
TP P G Y +G LG G + P Y GP P + T P V P
Sbjct: 576 PTPPPQGE-YLPDMG-LGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPV 633
Query: 1493 KTQRLLHS 1500
K +LL++
Sbjct: 634 KFNKLLYN 641
>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
Length = 744
Score = 66.6 bits (161), Expect = 2e-10
Identities = 47/122 (38%), Positives = 55/122 (45%), Gaps = 28/122 (22%)
Query: 1377 EGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGV 1436
+G+ G PPG+P + GP P GPP P G PGLPG PPG G
Sbjct: 491 QGLQG--PPGIPGIGGPSG------------PIGPPGIPGPKGEPGLPG--PPGFPGIGK 534
Query: 1437 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPG-PHPAGPPVIQQPTTPMFVAPPPKTQ 1495
+ G P G P G LGP GQ P PG P P GPP + PT PPP+ +
Sbjct: 535 PGVAGLHGPPGKP-----GALGPQGQPGLPGPPGPPGPPGPPAVMPPT------PPPQGE 583
Query: 1496 RL 1497
L
Sbjct: 584 YL 585
Score = 57.4 bits (137), Expect = 1e-07
Identities = 39/90 (43%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 1384 PPGLPPLQGPVDGLVSMGSMQPLHPG--GPPPHHLPPGVPGLPGIPPPGVMN-QGVAPMV 1440
P GLP QG G P PG GPP H PPG GLPG+ PGV G +
Sbjct: 227 PKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPL 286
Query: 1441 GTPAPGGSPYGQQVGVLGPPGQQAPPPYPG 1470
G P G P Q G +G PG Q PP PG
Sbjct: 287 GKPGAPGEPGPQ--GPIGVPGVQGPPGIPG 314
Score = 51.6 bits (122), Expect = 6e-06
Identities = 48/148 (32%), Positives = 60/148 (40%), Gaps = 40/148 (27%)
Query: 1380 MGGYP--PGLPPLQGPVDGLVSMGSMQP------LHPGGPPPHHLPPGVPGLPGIP---- 1427
+GG P PGLP + GP+ ++G P + P GPP PG+ G PG P
Sbjct: 385 IGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLG 444
Query: 1428 ---PPGVMN-------QGVAPMVGTPAPGGSPYGQQVGVLGPPGQ---------QAPPPY 1468
PPG+ +G A G P G P G+LGP G+ Q PP
Sbjct: 445 EVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVP-----GLLGPKGEPGIPGDQGLQGPPGI 499
Query: 1469 PG----PHPAGPPVIQQPTTPMFVAPPP 1492
PG P GPP I P + PP
Sbjct: 500 PGIGGPSGPIGPPGIPGPKGEPGLPGPP 527
Score = 51.2 bits (121), Expect = 8e-06
Identities = 39/111 (35%), Positives = 46/111 (41%), Gaps = 3/111 (2%)
Query: 1385 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1444
PG P G V G P+ P G PG+PG+PG+ P G+ G
Sbjct: 437 PGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGP-KGEPGIPGDQGLQG 495
Query: 1445 PGGSP-YGQQVGVLGPPGQQAPPPYPG-PHPAGPPVIQQPTTPMFVAPPPK 1493
P G P G G +GPPG P PG P P G P I +P PP K
Sbjct: 496 PPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGK 546
Score = 48.1 bits (113), Expect = 7e-05
Identities = 39/117 (33%), Positives = 47/117 (40%), Gaps = 11/117 (9%)
Query: 1385 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMN-------QGVA 1437
PG P G +G + P G P PPG GLPGI PG +G
Sbjct: 166 PGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDR 225
Query: 1438 PMVGTPAPGG--SPYGQQ-VGVLGPPGQQAPPPYPG-PHPAGPPVIQQPTTPMFVAP 1490
G P P G P G + G+ G PG + PP G P P G P + +P F P
Sbjct: 226 GPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGP 282
Score = 48.1 bits (113), Expect = 7e-05
Identities = 37/100 (37%), Positives = 42/100 (42%), Gaps = 21/100 (21%)
Query: 1384 PPGLPPL-------------QGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPG 1430
PPGLP + G V G ++G P G P PPG PGLPGIP P
Sbjct: 344 PPGLPGIGKPGFPGPKGDRGMGGVPG--ALGPRGEKGPIGAPGIGGPPGEPGLPGIPGP- 400
Query: 1431 VMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPG 1470
G +G P P G G VG GPPG + P G
Sbjct: 401 ---MGPPGAIGFPGPKGE--GGIVGPQGPPGPKGEPGLQG 435
Score = 47.0 bits (110), Expect = 1e-04
Identities = 42/109 (38%), Positives = 48/109 (44%), Gaps = 15/109 (13%)
Query: 1384 PPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIP-------PPGVMNQGV 1436
PPG+ GPV GL +G +P G P P P G PG PG P PGV
Sbjct: 256 PPGMHGPPGPV-GLPGVG--KPGVTGFPGPQG-PLGKPGAPGEPGPQGPIGVPGVQGPPG 311
Query: 1437 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTP 1485
P +G P G P Q G G G+Q P PG P G P I +P P
Sbjct: 312 IPGIGKPGQDGIP--GQPGFPGGKGEQGLPGLPG--PPGLPGIGKPGFP 356
Score = 46.6 bits (109), Expect = 2e-04
Identities = 43/123 (34%), Positives = 50/123 (40%), Gaps = 26/123 (21%)
Query: 1384 PPGLPPLQGPVDGLVSMGSMQPLHPG-----GPPPHHLPPGVPGLPGI------------ 1426
P G+P QGP G +P PG GP P G+PG G+
Sbjct: 189 PMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMP 248
Query: 1427 PPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAP------PPYPGPH-PAGPPVI 1479
PGV +G M G P P G P + GV G PG Q P P PGP P G P +
Sbjct: 249 GAPGV--KGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGV 306
Query: 1480 QQP 1482
Q P
Sbjct: 307 QGP 309
Score = 46.2 bits (108), Expect = 2e-04
Identities = 42/131 (32%), Positives = 50/131 (38%), Gaps = 43/131 (32%)
Query: 1386 GLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVP-----------------------G 1422
G P QGP+ + G P P G P PPG+P G
Sbjct: 278 GFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQG 337
Query: 1423 LPGIP-PPGVMNQGVAPMVGTPAPGG-----------SPYGQQVGVLGPPGQQAPPPYPG 1470
LPG+P PPG+ G G P P G P G++ G +G PG PP PG
Sbjct: 338 LPGLPGPPGLPGIG---KPGFPGPKGDRGMGGVPGALGPRGEK-GPIGAPGIGGPPGEPG 393
Query: 1471 ----PHPAGPP 1477
P P GPP
Sbjct: 394 LPGIPGPMGPP 404
Score = 43.5 bits (101), Expect = 0.002
Identities = 37/107 (34%), Positives = 42/107 (39%), Gaps = 22/107 (20%)
Query: 1410 GPPPHHLPPGVPGLPGIPP---------------PGVMNQGVAPMVGTPAPGGSPYGQ-- 1452
GP P G PG PG+P PGV G+ M G P G P +
Sbjct: 121 GPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGE 180
Query: 1453 --QVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPP-PKTQR 1496
Q G +GP G P PGPH G P I +P P P PK R
Sbjct: 181 IGQKGEIGPMGIPGPQGPPGPH--GLPGIGKPGGPGLPGQPGPKGDR 225
Score = 39.3 bits (90), Expect = 0.031
Identities = 45/128 (35%), Positives = 53/128 (41%), Gaps = 14/128 (10%)
Query: 1384 PPGLPPLQGPVDGLVSMGS--MQPLH-PGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMV 1440
P G P L GP G +G + LH P G P P G PGLPG P P A M
Sbjct: 517 PKGEPGLPGP-PGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMP 575
Query: 1441 GTPAPGGSPYGQQVGVLGPPGQQAPPPY-------PGPHPAGPPVIQQPTTPM-FVAPPP 1492
TP P G Y +G LG G + P Y GP P + T P V P
Sbjct: 576 PTPPPQGE-YLPDMG-LGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPV 633
Query: 1493 KTQRLLHS 1500
K +LL++
Sbjct: 634 KFNKLLYN 641
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 62.0 bits (149), Expect = 4e-09
Identities = 80/268 (29%), Positives = 107/268 (39%), Gaps = 41/268 (15%)
Query: 1267 RKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSE--STPKSAKGSAKKEG 1324
RK KE +PL +++ + E EG + +EE E+D E S A+ ++K+
Sbjct: 318 RKKKKNMKELTPLQAMMLRMAGQEIPE-EGRE--VEEFSEDDDEDDSDDSEAEKQSQKQ- 373
Query: 1325 SKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYP 1384
K + + G SS+ +A ++ P + G P
Sbjct: 374 HKEESHSDGTSTASSQQQAPPQSVPPSQ------------------IQAPPMPGPPPLGP 415
Query: 1385 PGLPPLQ--GPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGT 1442
P PPL+ GP GL P P G PP PPG+PGL G P P ++ G P
Sbjct: 416 PPAPPLRPPGPPTGL------PPGPPPGAPPFLRPPGMPGLRG-PLPRLLPPGPPPGRPP 468
Query: 1443 PAPGGSPYGQQVG--VLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHS 1500
P G P G G GPP + PP PG P P +++ P P PP L
Sbjct: 469 GPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPG----LFP 524
Query: 1501 EAYLKYIEGLSAESNSIS--KWDQTLAA 1526
A L LSA N I K D T AA
Sbjct: 525 PAPLPNPGVLSAPPNLIQRPKADDTSAA 552
Score = 33.1 bits (74), Expect = 2.2
Identities = 27/70 (38%), Positives = 35/70 (50%), Gaps = 5/70 (7%)
Query: 1412 PPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPY-GQQVGVLGPPGQQAPPPYPG 1470
P + L +P LPG PP ++ + A T A P G V L PPG++ P P PG
Sbjct: 148 PSNILIQDIP-LPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRL-PPGRKPPGPPPG 205
Query: 1471 PHPAGPPVIQ 1480
P P P V+Q
Sbjct: 206 PPP--PQVVQ 213
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 61.6 bits (148), Expect = 6e-09
Identities = 50/122 (40%), Positives = 55/122 (45%), Gaps = 19/122 (15%)
Query: 1384 PPGLPP----LQGPVDGLVSMGSMQP---LHPGGP----PPHHLPPGVPG-LPGI-PPPG 1430
PPG PP L P+ G + G P L PG P P LPPG P +PG PPPG
Sbjct: 249 PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPG 308
Query: 1431 VMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY-PGPHPAGPPVIQQPTTPMFVA 1489
P G P P G + G LGPP APPP+ PGP P PP P F
Sbjct: 309 PP----PPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPH-VNPAFFP 363
Query: 1490 PP 1491
PP
Sbjct: 364 PP 365
Score = 58.5 bits (140), Expect = 5e-08
Identities = 47/136 (34%), Positives = 53/136 (38%), Gaps = 30/136 (22%)
Query: 1385 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGV-APMVGTP 1443
PG P G G P P G P P G PG PG P P Q + P+ G P
Sbjct: 208 PGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPP 267
Query: 1444 APG----------GSPYGQ-QVGVL----------------GPPGQQAPPPYPGPHPAGP 1476
G G P+GQ +G L PP QQ PPP PGP P P
Sbjct: 268 NRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRP 327
Query: 1477 PVIQQPTTPMFVAPPP 1492
P P P+ +APPP
Sbjct: 328 PGPLGP--PLTLAPPP 341
Score = 42.0 bits (97), Expect = 0.005
Identities = 37/120 (30%), Positives = 44/120 (36%), Gaps = 26/120 (21%)
Query: 1380 MGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVA-- 1437
+G PPG PP PV G PG PPP PP PG PPG + +
Sbjct: 289 LGPLPPGPPP---PVPGYGPP-------PGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLA 338
Query: 1438 --PMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQ---PTTPMFVAPPP 1492
P + P PG P P P +P P +G P P T + PPP
Sbjct: 339 PPPHLPGPPPGAPP---------PAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389
Score = 37.7 bits (86), Expect = 0.089
Identities = 33/92 (35%), Positives = 34/92 (36%), Gaps = 11/92 (11%)
Query: 1408 PGGPPPHHLPPGVPG---LPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQA 1464
PGG P G G PG P G G A G P P P GQ PP
Sbjct: 189 PGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPP--FPAGQT-----PPRPPL 241
Query: 1465 PPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQR 1496
PP P P P GPP Q P PP + R
Sbjct: 242 GPPGP-PGPPGPPPPGQVLPPPLAGPPNRGDR 272
Score = 35.4 bits (80), Expect = 0.44
Identities = 27/77 (35%), Positives = 31/77 (40%), Gaps = 14/77 (18%)
Query: 1428 PPGVMNQGVAPMVGTPA---PGGSPYGQQV-GVLGPPGQQAPPPYPGPH--------PAG 1475
PPG ++ P G PG P G + G GP G PPP+P P G
Sbjct: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGP--PPPFPAGQTPPRPPLGPPG 245
Query: 1476 PPVIQQPTTPMFVAPPP 1492
PP P P V PPP
Sbjct: 246 PPGPPGPPPPGQVLPPP 262
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 61.2 bits (147), Expect = 7e-09
Identities = 63/189 (33%), Positives = 75/189 (39%), Gaps = 33/189 (17%)
Query: 1365 WRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLP 1424
W N ++ Y GM GG P G P GP + S+ H GG P H P G P
Sbjct: 368 WMNSGPSESRPYHGMHGGGPGG--PGGGPHSFPHPLPSLTGGH-GGHPMQHNPNGPPPPW 424
Query: 1425 GIPPPGVMNQGVAPMVGTPAP------GGSPYGQQV-------GVLGPP--GQQAPPP-- 1467
PPP MNQG P P G +P G V G++ PP G PPP
Sbjct: 425 MQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPP 484
Query: 1468 ---YPGPHPAG--PPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEG-----LSAESNSI 1517
P P P+G PP QQ P PPP + S L + + SA + SI
Sbjct: 485 PSGQPPPPPSGPLPPWQQQQQQP---PPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSI 541
Query: 1518 SKWDQTLAA 1526
W Q AA
Sbjct: 542 PPWQQQQAA 550
Score = 40.0 bits (92), Expect = 0.018
Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 9/57 (15%)
Query: 1385 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVG 1441
PG P +QG +M PL PG PP LPPG P P PPPG + P G
Sbjct: 555 PGAPQMQGNP-------TMVPLPPGVQPP--LPPGAPPPPPPPPPGSAGMMIPPRGG 602
Score = 35.4 bits (80), Expect = 0.44
Identities = 38/132 (28%), Positives = 43/132 (32%), Gaps = 27/132 (20%)
Query: 1380 MGGYPPGLPPLQG----PVDGLVSMGSMQPLHPGGPPP--HHLPPGVP------------ 1421
MG PP PP G P G + Q P PPP + P
Sbjct: 475 MGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTT 534
Query: 1422 --GLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVI 1479
G IPP A G P G+P V PPG Q P P P P PP
Sbjct: 535 SAGTGSIPPWQQQQAAAAASPGAPQMQGNP----TMVPLPPGVQPPLPPGAPPPPPPP-- 588
Query: 1480 QQPTTPMFVAPP 1491
P + + PP
Sbjct: 589 -PPGSAGMMIPP 599
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 61.2 bits (147), Expect = 7e-09
Identities = 63/189 (33%), Positives = 75/189 (39%), Gaps = 33/189 (17%)
Query: 1365 WRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLP 1424
W N ++ Y GM GG P G P GP + S+ H GG P H P G P
Sbjct: 368 WMNSGPSESRPYHGMHGGGPGG--PGGGPHSFPHPLPSLTGGH-GGHPMQHNPNGPPPPW 424
Query: 1425 GIPPPGVMNQGVAPMVGTPAP------GGSPYGQQV-------GVLGPP--GQQAPPP-- 1467
PPP MNQG P P G +P G V G++ PP G PPP
Sbjct: 425 MQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPP 484
Query: 1468 ---YPGPHPAG--PPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEG-----LSAESNSI 1517
P P P+G PP QQ P PPP + S L + + SA + SI
Sbjct: 485 PSGQPPPPPSGPLPPWQQQQQQP---PPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSI 541
Query: 1518 SKWDQTLAA 1526
W Q AA
Sbjct: 542 PPWQQQQAA 550
Score = 47.8 bits (112), Expect = 9e-05
Identities = 35/92 (38%), Positives = 38/92 (41%), Gaps = 12/92 (13%)
Query: 1385 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1444
PG P +QG +M PL PG PP LPPG P P PPPG AP P
Sbjct: 555 PGAPQMQGNP-------TMVPLPPGVQPP--LPPGAPPPPPPPPPGSAGMMYAPPPPPPP 605
Query: 1445 ---PGGSPYGQQVGVLGPPGQQAPPPYPGPHP 1473
P +GV G P PP P P P
Sbjct: 606 PMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPP 637
Score = 38.5 bits (88), Expect = 0.052
Identities = 39/135 (28%), Positives = 45/135 (33%), Gaps = 26/135 (19%)
Query: 1380 MGGYPPGLPPLQG----PVDGLVSMGSMQPLHPGGPPP--HHLPPGVP------------ 1421
MG PP PP G P G + Q P PPP + P
Sbjct: 475 MGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTT 534
Query: 1422 --GLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQV--GVLGPPGQQAPPPYPGPHPAGPP 1477
G IPP A G P G+P + GV P APPP P P P
Sbjct: 535 SAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAG 594
Query: 1478 VIQQPTTPMFVAPPP 1492
++ P P PPP
Sbjct: 595 MMYAPPPP----PPP 605
>gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]
Length = 832
Score = 60.5 bits (145), Expect = 1e-08
Identities = 52/222 (23%), Positives = 97/222 (43%), Gaps = 22/222 (9%)
Query: 416 KYPDYYQQIKMPISLQQIRTKLKN--QEYETLDHLECDLN--LMFENAKRYNVPNSAIYK 471
K + ++IK+P +TK ++YE + C+LN + + I K
Sbjct: 618 KKQGFSKEIKIP------KTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEIIK 671
Query: 472 RVLKLQQVMQAKK-------KELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMK 524
++++ +Q K K+ R+ IE + + +G K K ++ +
Sbjct: 672 KLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQ---- 727
Query: 525 ILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEE 584
L++ + + + FM + + P YY++I PMDLK + ++N Y ++
Sbjct: 728 -LYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKK 786
Query: 585 GMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELG 626
+ D++ +F N + YN S+ Y A+ILEK K KE G
Sbjct: 787 LFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAG 828
Score = 60.1 bits (144), Expect = 2e-08
Identities = 28/79 (35%), Positives = 46/79 (58%)
Query: 208 FQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGS 267
F + + + P YY +I+ P+DLKT+++R++N Y S D+ + N K YN P S
Sbjct: 748 FMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPES 807
Query: 268 QVFKDANSIKKIFYMKKAE 286
+ +K AN ++K F+ K E
Sbjct: 808 EYYKCANILEKFFFSKIKE 826
Score = 55.8 bits (133), Expect = 3e-07
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Query: 388 QLYDTVRSCRNN-QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLD 446
QLY T++S + A PF + + P YY+ I+ P+ L+ + +LKN+ Y +
Sbjct: 727 QLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKK 786
Query: 447 HLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKE 486
DL +F N K YN P S YK L++ +K KE
Sbjct: 787 LFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
Score = 55.8 bits (133), Expect = 3e-07
Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Query: 52 ELYNTIRDYKDE-QGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVN 110
+LY+T++ + + F+ KR P YYEV+ P+DL + ++LK Y
Sbjct: 727 QLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKK 786
Query: 111 LLTADFQLLFNNAKSYYKPDSPEYKAA 137
L AD Q +F N K Y P+S YK A
Sbjct: 787 LFMADLQRVFTNCKEYNPPESEYYKCA 813
Score = 47.8 bits (112), Expect = 9e-05
Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 4/114 (3%)
Query: 643 RKSGISPK-KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI-FLRLPSRSELPDYYLTI 700
R++G P K K P +++Y +K+ + SA F+ R+E P YY I
Sbjct: 707 RETGWKPSGKEKSKEPRDP--DQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVI 764
Query: 701 KKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHK 754
+ PMD++ + + Y + D +F N YN PES YK A +L K
Sbjct: 765 RFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEK 818
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 60.1 bits (144), Expect = 2e-08
Identities = 32/106 (30%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
Query: 188 QLLEAIVVATNPSGRLISELFQKLPS-KVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIH 246
Q ++ +VV T + +Q + + K+ PDY+ IIK P+D+ TI +R++N Y S
Sbjct: 40 QYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSAS 99
Query: 247 AMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEM 292
+D + + N YN+P + A +++KIF K A++ E+
Sbjct: 100 ECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEV 145
Score = 52.8 bits (125), Expect = 3e-06
Identities = 28/80 (35%), Positives = 39/80 (48%)
Query: 693 LPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVL 752
LPDY+ IK PMDM I+ + N Y ++DF MF N YN+P I A L
Sbjct: 70 LPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQAL 129
Query: 753 HKVLLETRRDLEGDEDSHVP 772
K+ L+ + +E +P
Sbjct: 130 EKIFLQKVAQMPQEEVELLP 149
Score = 52.8 bits (125), Expect = 3e-06
Identities = 33/124 (26%), Positives = 54/124 (43%), Gaps = 17/124 (13%)
Query: 83 DYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWD 142
DY++++ P+DL +++K+ EY D AD +L+F+N Y PD A KL D
Sbjct: 347 DYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQD 406
Query: 143 L----YLRTRNE-------------FVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEI 185
+ + + +E V KG +E D+ + +E L E+
Sbjct: 407 VFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAEL 466
Query: 186 LEQL 189
EQL
Sbjct: 467 QEQL 470
Score = 51.6 bits (122), Expect = 6e-06
Identities = 39/156 (25%), Positives = 67/156 (42%), Gaps = 9/156 (5%)
Query: 219 DYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKK 278
DY+ IIK P+DL T+ +++ Y A D+ L+ N YN P +V A ++
Sbjct: 347 DYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQD 406
Query: 279 IFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQ 338
+F M+ A++ + +L P+ A G S+ S + S +RA +
Sbjct: 407 VFEMRFAKMPDEPVEAPAL----PAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATR 462
Query: 339 GGRLSAITMALQYGSESEEDAALAAARYEEGESEAE 374
L Q + E+ AAL+ A + + + E
Sbjct: 463 LAELQE-----QLKAVHEQLAALSQAPVNKPKKKKE 493
Score = 48.5 bits (114), Expect = 5e-05
Identities = 24/70 (34%), Positives = 36/70 (51%)
Query: 552 KKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDA 611
K + PDY+KII PMD+ I+ + N+ Y ++D MF N YN+ + A
Sbjct: 67 KLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMA 126
Query: 612 HILEKLLKEK 621
LEK+ +K
Sbjct: 127 QALEKIFLQK 136
Score = 47.4 bits (111), Expect = 1e-04
Identities = 58/238 (24%), Positives = 89/238 (37%), Gaps = 64/238 (26%)
Query: 692 ELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALV 751
EL DY+ IK PMD+ ++ M +Y D D +MF+N YN P+
Sbjct: 344 ELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPD--------- 394
Query: 752 LHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVD 811
H+V+ R+ +Q++ F + D E PA+
Sbjct: 395 -HEVVAMARK----------------LQDVFEMRFAKM-----------PDEPVEAPAL- 425
Query: 812 PNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDA--VELQ 869
P ++ K E++R E + +DSE ELQ
Sbjct: 426 ------PAPAAPMVSKGAESSRSSE------------ESSSDSGSSDSEEERATRLAELQ 467
Query: 870 QFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEK-LPKEIEEDKLKREEEKR 926
+ + ++L LS A K EKE+K+K KE E+ K+K EEEK+
Sbjct: 468 EQLKAVHEQLA-----ALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKK 520
Score = 47.4 bits (111), Expect = 1e-04
Identities = 21/65 (32%), Positives = 33/65 (50%)
Query: 419 DYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQ 478
DY+ IK P+ L ++ K+ +EY D+ LMF N +YN P+ + KLQ
Sbjct: 347 DYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQD 406
Query: 479 VMQAK 483
V + +
Sbjct: 407 VFEMR 411
Score = 44.3 bits (103), Expect = 0.001
Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 405 AEPFYHLPS--KKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRY 462
A PFY K PDY++ IK P+ + I+ +L+N Y + D N MF N Y
Sbjct: 56 AWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIY 115
Query: 463 NVPNSAIYKRVLKLQQVMQAKKKELARRD 491
N P I L+++ K ++ + +
Sbjct: 116 NKPTDDIVLMAQALEKIFLQKVAQMPQEE 144
Score = 42.7 bits (99), Expect = 0.003
Identities = 31/139 (22%), Positives = 61/139 (43%), Gaps = 2/139 (1%)
Query: 557 DYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEK 616
DY+ II PMDL ++ + +Y +G D++LMF N YN +V A L+
Sbjct: 347 DYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQD 406
Query: 617 LLKEKRKELGPLP-DDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDK 675
+ + + ++ P + + +P + K S + S+ + + E +
Sbjct: 407 VFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAEL 466
Query: 676 RGRRLSAIFLRLPSRSELP 694
+ +L A+ +L + S+ P
Sbjct: 467 Q-EQLKAVHEQLAALSQAP 484
Score = 39.7 bits (91), Expect = 0.023
Identities = 19/67 (28%), Positives = 34/67 (50%)
Query: 80 NQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACK 139
N PDY++++ P+D+ I+++L+ Y + DF +F N Y KP A
Sbjct: 69 NLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQA 128
Query: 140 LWDLYLR 146
L ++L+
Sbjct: 129 LEKIFLQ 135
Score = 31.2 bits (69), Expect = 8.3
Identities = 27/101 (26%), Positives = 40/101 (39%), Gaps = 9/101 (8%)
Query: 1393 PVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQ 1452
PV + + + P+ P PP P VP +P PP V +GV T P S
Sbjct: 200 PVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPV-VKKKGVKRKADTTTPTTS---- 254
Query: 1453 QVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPK 1493
+ ++PPP P A V ++ + + PP K
Sbjct: 255 ---AITASRSESPPPLSDPKQA-KVVARRESGGRPIKPPKK 291
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 59.3 bits (142), Expect = 3e-08
Identities = 27/78 (34%), Positives = 44/78 (56%)
Query: 214 KVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDA 273
K+ PDYY IIK P+D+ TI +R++N Y + +D + + N YN+PG + A
Sbjct: 91 KLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMA 150
Query: 274 NSIKKIFYMKKAEIEHHE 291
+++K+F K E+ E
Sbjct: 151 EALEKLFLQKINELPTEE 168
Score = 58.2 bits (139), Expect = 6e-08
Identities = 30/74 (40%), Positives = 40/74 (54%)
Query: 552 KKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDA 611
K + PDYYKII PMD+ I+ + N+ Y + I+D MF N YN+ G + A
Sbjct: 91 KLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMA 150
Query: 612 HILEKLLKEKRKEL 625
LEKL +K EL
Sbjct: 151 EALEKLFLQKINEL 164
Score = 55.1 bits (131), Expect = 5e-07
Identities = 29/75 (38%), Positives = 39/75 (52%)
Query: 693 LPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVL 752
LPDYY IK PMDM I+ + N Y + ++DF MF N YN+P I A L
Sbjct: 94 LPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEAL 153
Query: 753 HKVLLETRRDLEGDE 767
K+ L+ +L +E
Sbjct: 154 EKLFLQKINELPTEE 168
Score = 50.1 bits (118), Expect = 2e-05
Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 4/105 (3%)
Query: 219 DYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKK 278
DY IIK P+D+ TI +++ Y+ D+ L+ N YN P +V A ++
Sbjct: 389 DYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQD 448
Query: 279 IFYMKKA----EIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGS 319
+F M+ A E E +A SS + P+ + A + S S S
Sbjct: 449 VFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSS 493
Score = 48.5 bits (114), Expect = 5e-05
Identities = 61/243 (25%), Positives = 98/243 (40%), Gaps = 68/243 (27%)
Query: 693 LPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVL 752
L DY IK PMDM I+S + A +Y+D D +MF+N YN P+
Sbjct: 387 LHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPD---------- 436
Query: 753 HKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDP 812
H+V+ R+ +Q++ F + ++ S PAV P
Sbjct: 437 HEVVAMARK----------------LQDVFEMRFAKMPDEPEEPVVAVSS-----PAVPP 475
Query: 813 NFPNK---PPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQ 869
P K PP + D + ++ D + ERA+R+ ELQ
Sbjct: 476 --PTKVVAPPSSSDSSSDSSSDSDSSTDDSEE-------ERAQRL-----------AELQ 515
Query: 870 QFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAE 929
+ + ++L ALS ++ EK++KEK +++K KR+EE E +
Sbjct: 516 EQLKAVHEQLA---------ALSQPQQNKPKKKEKDKKEK-----KKEKHKRKEEVEENK 561
Query: 930 KSE 932
KS+
Sbjct: 562 KSK 564
Score = 48.1 bits (113), Expect = 7e-05
Identities = 22/62 (35%), Positives = 34/62 (54%)
Query: 83 DYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWD 142
DY +++ P+D+ I+ KL+ EY D AD +L+F+N Y PD A KL D
Sbjct: 389 DYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQD 448
Query: 143 LY 144
++
Sbjct: 449 VF 450
Score = 47.8 bits (112), Expect = 9e-05
Identities = 22/65 (33%), Positives = 34/65 (52%)
Query: 419 DYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQ 478
DY IK P+ + I++KL+ +EY D+ LMF N +YN P+ + KLQ
Sbjct: 389 DYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQD 448
Query: 479 VMQAK 483
V + +
Sbjct: 449 VFEMR 453
Score = 46.2 bits (108), Expect = 2e-04
Identities = 33/104 (31%), Positives = 46/104 (44%), Gaps = 10/104 (9%)
Query: 414 KKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRV 473
K PDYY+ IK P+ + I+ +L+N Y D N MF N YN P I
Sbjct: 91 KLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMA 150
Query: 474 LKLQQVMQAKKKELARRDDIEDGDSMISSA------TSDTGSAK 511
L+++ K EL E+ + MI A +TG+AK
Sbjct: 151 EALEKLFLQKINEL----PTEETEIMIVQAKGRGRGRKETGTAK 190
Score = 44.3 bits (103), Expect = 0.001
Identities = 23/71 (32%), Positives = 36/71 (50%)
Query: 80 NQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACK 139
N PDYY+++ P+D+ I+++L+ Y + DF +F N Y KP A
Sbjct: 93 NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEA 152
Query: 140 LWDLYLRTRNE 150
L L+L+ NE
Sbjct: 153 LEKLFLQKINE 163
Score = 37.7 bits (86), Expect = 0.089
Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 2/98 (2%)
Query: 557 DYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEK 616
DY II PMD+ I+ + +Y + D++LMF N YN +V A L+
Sbjct: 389 DYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQD 448
Query: 617 LLKEKRKELGPLPDDDDMA--SPKLKLSRKSGISPKKS 652
+ + + ++ P++ +A SP + K P S
Sbjct: 449 VFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSS 486
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,754,299
Number of Sequences: 37866
Number of extensions: 3808980
Number of successful extensions: 33719
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 348
Number of HSP's successfully gapped in prelim test: 819
Number of HSP's that attempted gapping in prelim test: 18436
Number of HSP's gapped (non-prelim): 8233
length of query: 1582
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1466
effective length of database: 13,855,062
effective search space: 20311520892
effective search space used: 20311520892
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.