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Search of human proteins with 92110053
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
(3487 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 7326 0.0
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 4371 0.0
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 4341 0.0
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 3696 0.0
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 3696 0.0
gi|148886654 polydom [Homo sapiens] 436 e-121
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi... 282 5e-75
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi... 282 5e-75
gi|54792123 complement component (3d/Epstein Barr virus) recepto... 278 7e-74
gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens] 271 8e-72
gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens] 271 8e-72
gi|42544177 complement component (3d/Epstein Barr virus) recepto... 265 5e-70
gi|32261332 seizure related 6 homolog (mouse)-like precursor [Ho... 260 1e-68
gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3 ... 232 6e-60
gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 ... 232 6e-60
gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [H... 232 6e-60
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 217 1e-55
gi|157419154 selectin P precursor [Homo sapiens] 215 5e-55
gi|22547221 tolloid-like 1 [Homo sapiens] 213 3e-54
gi|6912724 tolloid-like 2 [Homo sapiens] 206 3e-52
gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 ... 193 3e-48
gi|148922949 complement component (3b/4b) receptor 1-like [Homo ... 182 5e-45
gi|187960042 selectin E precursor [Homo sapiens] 177 1e-43
gi|62739186 complement factor H isoform a precursor [Homo sapiens] 166 5e-40
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 154 1e-36
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 154 1e-36
gi|4502503 complement component 4 binding protein, alpha chain p... 151 1e-35
gi|13899255 membrane frizzled-related protein [Homo sapiens] 123 3e-27
gi|62739188 complement factor H isoform b precursor [Homo sapiens] 120 3e-26
gi|110611237 coagulation factor XIII B subunit precursor [Homo s... 112 6e-24
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 7326 bits (19007), Expect = 0.0
Identities = 3487/3487 (100%), Positives = 3487/3487 (100%)
Query: 1 MRLISIAPGPRWQVQSHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEE 60
MRLISIAPGPRWQVQSHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEE
Sbjct: 1 MRLISIAPGPRWQVQSHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEE 60
Query: 61 QHRIQLVFQSFALEEDFDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDY 120
QHRIQLVFQSFALEEDFDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDY
Sbjct: 61 QHRIQLVFQSFALEEDFDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDY 120
Query: 121 AVSAQGFHATYEVLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCH 180
AVSAQGFHATYEVLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCH
Sbjct: 121 AVSAQGFHATYEVLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCH 180
Query: 181 AGSENSATWDFPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTI 240
AGSENSATWDFPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTI
Sbjct: 181 AGSENSATWDFPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTI 240
Query: 241 ALVFIDFQLEDGYDFLEVTGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFS 300
ALVFIDFQLEDGYDFLEVTGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFS
Sbjct: 241 ALVFIDFQLEDGYDFLEVTGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFS 300
Query: 301 AQYQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFR 360
AQYQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFR
Sbjct: 301 AQYQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFR 360
Query: 361 LGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPN 420
LGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPN
Sbjct: 361 LGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPN 420
Query: 421 FPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTG 480
FPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTG
Sbjct: 421 FPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTG 480
Query: 481 TSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHG 540
TSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHG
Sbjct: 481 TSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHG 540
Query: 541 DTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGN 600
DTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGN
Sbjct: 541 DTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGN 600
Query: 601 HLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSS 660
HLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSS
Sbjct: 601 HLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSS 660
Query: 661 GHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEG 720
GHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEG
Sbjct: 661 GHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEG 720
Query: 721 FLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAW 780
FLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAW
Sbjct: 721 FLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAW 780
Query: 781 VIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYL 840
VIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYL
Sbjct: 781 VIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYL 840
Query: 841 LFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLS 900
LFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLS
Sbjct: 841 LFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLS 900
Query: 901 DGEPLECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGK 960
DGEPLECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGK
Sbjct: 901 DGEPLECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGK 960
Query: 961 GVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDF 1020
GVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDF
Sbjct: 961 GVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDF 1020
Query: 1021 SMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCL 1080
SMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCL
Sbjct: 1021 SMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCL 1080
Query: 1081 GGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKA 1140
GGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKA
Sbjct: 1081 GGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKA 1140
Query: 1141 RAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFE 1200
RAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFE
Sbjct: 1141 RAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFE 1200
Query: 1201 LHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTW 1260
LHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTW
Sbjct: 1201 LHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTW 1260
Query: 1261 DRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTE 1320
DRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTE
Sbjct: 1261 DRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTE 1320
Query: 1321 EVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVS 1380
EVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVS
Sbjct: 1321 EVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVS 1380
Query: 1381 TATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPT 1440
TATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPT
Sbjct: 1381 TATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPT 1440
Query: 1441 CIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLH 1500
CIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLH
Sbjct: 1441 CIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLH 1500
Query: 1501 IYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFD 1560
IYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFD
Sbjct: 1501 IYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFD 1560
Query: 1561 PGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCG 1620
PGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCG
Sbjct: 1561 PGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCG 1620
Query: 1621 GQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQ 1680
GQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQ
Sbjct: 1621 GQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQ 1680
Query: 1681 HSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPE 1740
HSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPE
Sbjct: 1681 HSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPE 1740
Query: 1741 PRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNL 1800
PRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNL
Sbjct: 1741 PRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNL 1800
Query: 1801 TERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTV 1860
TERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTV
Sbjct: 1801 TERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTV 1860
Query: 1861 TMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVK 1920
TMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVK
Sbjct: 1861 TMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVK 1920
Query: 1921 TGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVIL 1980
TGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVIL
Sbjct: 1921 TGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVIL 1980
Query: 1981 SPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSG 2040
SPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSG
Sbjct: 1981 SPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSG 2040
Query: 2041 SELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSFLRGFDLSELERTNST 2100
SELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSFLRGFDLSELERTNST
Sbjct: 2041 SELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSFLRGFDLSELERTNST 2100
Query: 2101 PPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPV 2160
PPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPV
Sbjct: 2101 PPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPV 2160
Query: 2161 LTCQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGV 2220
LTCQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGV
Sbjct: 2161 LTCQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGV 2220
Query: 2221 RLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGG 2280
RLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGG
Sbjct: 2221 RLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGG 2280
Query: 2281 IFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGT 2340
IFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGT
Sbjct: 2281 IFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGT 2340
Query: 2341 YLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVE 2400
YLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVE
Sbjct: 2341 YLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVE 2400
Query: 2401 YFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFK 2460
YFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFK
Sbjct: 2401 YFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFK 2460
Query: 2461 IRYSAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWS 2520
IRYSAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWS
Sbjct: 2461 IRYSAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWS 2520
Query: 2521 EAIPLCQALSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWS 2580
EAIPLCQALSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWS
Sbjct: 2521 EAIPLCQALSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWS 2580
Query: 2581 NRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQA 2640
NRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQA
Sbjct: 2581 NRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQA 2640
Query: 2641 NGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMA 2700
NGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMA
Sbjct: 2641 NGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMA 2700
Query: 2701 NGLWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDH 2760
NGLWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDH
Sbjct: 2701 NGLWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDH 2760
Query: 2761 HWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHW 2820
HWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHW
Sbjct: 2761 HWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHW 2820
Query: 2821 TGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGS 2880
TGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGS
Sbjct: 2821 TGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGS 2880
Query: 2881 WSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTW 2940
WSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTW
Sbjct: 2881 WSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTW 2940
Query: 2941 TGSDPECLVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTW 3000
TGSDPECLVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTW
Sbjct: 2941 TGSDPECLVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTW 3000
Query: 3001 NGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTG 3060
NGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTG
Sbjct: 3001 NGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTG 3060
Query: 3061 ELPQCFPVFCGDPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQ 3120
ELPQCFPVFCGDPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQ
Sbjct: 3061 ELPQCFPVFCGDPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQ 3120
Query: 3121 PSCIDPTLTTCADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSG 3180
PSCIDPTLTTCADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSG
Sbjct: 3121 PSCIDPTLTTCADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSG 3180
Query: 3181 TPPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTG 3240
TPPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTG
Sbjct: 3181 TPPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTG 3240
Query: 3241 KPPICLEVRPSGRPINTAREPPLTQALIPGDVFAKNSLWKGAYEYQGKKQPAMLRVTGFQ 3300
KPPICLEVRPSGRPINTAREPPLTQALIPGDVFAKNSLWKGAYEYQGKKQPAMLRVTGFQ
Sbjct: 3241 KPPICLEVRPSGRPINTAREPPLTQALIPGDVFAKNSLWKGAYEYQGKKQPAMLRVTGFQ 3300
Query: 3301 VANSKVNATMIDHSGVELHLAGTYKKEDFHLLLQVYQITGPVEIFMNKFKDDHWALDGHV 3360
VANSKVNATMIDHSGVELHLAGTYKKEDFHLLLQVYQITGPVEIFMNKFKDDHWALDGHV
Sbjct: 3301 VANSKVNATMIDHSGVELHLAGTYKKEDFHLLLQVYQITGPVEIFMNKFKDDHWALDGHV 3360
Query: 3361 SSESSGATFIYQGSVKGQGFGQFGFQRLDLRLLESDPESIGRHFASNSSSVAAAILVPFI 3420
SSESSGATFIYQGSVKGQGFGQFGFQRLDLRLLESDPESIGRHFASNSSSVAAAILVPFI
Sbjct: 3361 SSESSGATFIYQGSVKGQGFGQFGFQRLDLRLLESDPESIGRHFASNSSSVAAAILVPFI 3420
Query: 3421 ALIIAGFVLYLYKHRRRPKVPFNGYAGHENTNVRATFENPMYDRNIQPTDIMASEAEFTV 3480
ALIIAGFVLYLYKHRRRPKVPFNGYAGHENTNVRATFENPMYDRNIQPTDIMASEAEFTV
Sbjct: 3421 ALIIAGFVLYLYKHRRRPKVPFNGYAGHENTNVRATFENPMYDRNIQPTDIMASEAEFTV 3480
Query: 3481 STVCTAV 3487
STVCTAV
Sbjct: 3481 STVCTAV 3487
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 4371 bits (11337), Expect = 0.0
Identities = 2003/3529 (56%), Positives = 2570/3529 (72%), Gaps = 122/3529 (3%)
Query: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG 85
C L G NGT+ESPGFPYGYPN ANCTW I AEE++RIQ+VFQSFALEE++D LS++DG
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
Query: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRL 145
P P N RTRLTGF LP + S + SLRL SD+AVSA GF YE L S +CGNPG
Sbjct: 125 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVP 184
Query: 146 PNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGT 205
P G+ G+ F++GDK+RYSC G+ L+GH LTC A S N+A+WDFP+P CRA+DACGGT
Sbjct: 185 PKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGT 244
Query: 206 LRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSS 265
+RG SGIISSP FP+EYHNNADCTWTI+AE GDTI+L+F DFQ+E+ YD+LE+ G+E +
Sbjct: 245 MRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPT 304
Query: 266 LWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVKLMPSKDNS 325
+W +G ++P P+IS+KNWLRLHF +D NHR RGFSA YQVKK I+ KSRG KL P KDNS
Sbjct: 305 IWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFKLFPGKDNS 364
Query: 326 QKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMK 385
K S+L + G+ N+CPDPG PE GKR+GSDF LGS+VQF+C+E Y LQG+K ITC +
Sbjct: 365 NKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQR 424
Query: 386 VSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIK 445
++++FAAWSDHRPVC+ + C ++L+GPSG TSPNFP QYD+NA CVW+ITA+N +KVI+
Sbjct: 425 IAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQ 484
Query: 446 LAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGS 505
+ FEEFDLE GYDTLT+GDGG+ GD +TVL +LTG+ VPDLIVS + QMWL QTD S
Sbjct: 485 INFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVG 544
Query: 506 SLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNN 565
S+GFK +Y+EIE+ SCGDPG P YG REG F + D L+FECQ FEL+G+K+I CQ+NN
Sbjct: 545 SVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENN 604
Query: 566 QWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDV 625
QWSA P C+F C NFT+P G VLSP+YPE YGN+L+C+W I++ P SRIHL+FND D+
Sbjct: 605 QWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDL 664
Query: 626 EPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTT 685
E QFDFL +KDG + E+P+LGTF+G ++PS +TS+ H+ RLEFQ DHS RGFNIT+ T
Sbjct: 665 ESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 724
Query: 686 FRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAV 745
F HNECPDPG+P+N +RFGD+ QLGSSIS +C+EGF+ TQG+ETITC+L +G V+W+ +
Sbjct: 725 FGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLI 784
Query: 746 LRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDT 805
+C APCGGH ++PSG ILSPGWPG+YKD+L+C WVIEA+PG+ IKITF+RF+TE+NYD
Sbjct: 785 PKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDV 844
Query: 806 LEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSD 865
LEV DG +PL+G Y+GTQVPQFL S+SN++YLLF+TD S S+ GF++ YE++T+ +
Sbjct: 845 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTY 904
Query: 866 HCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCG 925
CLDPGIPV+G+R+G+DF +G+ V+FSCDSGY LS EPL CE N WS LP+C+ALCG
Sbjct: 905 SCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCG 964
Query: 926 GFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGS 985
G ++G SGTILSPG+P+FYPN+LNCTW ++ +HGKGV F FHTFHLE HDYLLITENGS
Sbjct: 965 GDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGS 1024
Query: 986 FTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVP 1045
FTQPL +LTGS LP I+AGLYGNF AQ+RFISDFS+SYEGFNITFSEY+LEPCE+P +P
Sbjct: 1025 FTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIP 1084
Query: 1046 AYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGT 1105
Y R G FG+GDTLTFSC GYRLEGT+ I CLGG RR+WS+PLPRCVAECG S T
Sbjct: 1085 QYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNN 1144
Query: 1106 QGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLG 1165
+G LLSPN+P+NY NNHECIYSIQ Q GKGI + AR F L++GDVLK+YDG + + LLG
Sbjct: 1145 EGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLG 1204
Query: 1166 VFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHD 1225
F+ + M G+TL+STS+ LWL+F +D E T +GF+L ++SFEL CEDPG P+FGYK+ D
Sbjct: 1205 AFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISD 1264
Query: 1226 EGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLS 1285
+GHFAGS++ + C+PGY+L GS L C++GERR WD PLP+C+AECGG +GE SG++LS
Sbjct: 1265 QGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILS 1324
Query: 1286 PGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGP 1345
PGYP PY++NL C+W IE + G + L FL FDTE HD+LR+WDGP E+ +LLKE+SG
Sbjct: 1325 PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGS 1384
Query: 1346 ALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQNGSRSGDSWEAGD 1405
+P+ +HST N V +QF TDF+ SK GFAIQFS S AT+C DPG+P NG+R+GD E GD
Sbjct: 1385 LIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGD 1444
Query: 1406 STVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPY 1465
+ VFQCDPGY LQG I+C+++ENR+FWQPSPP CIAPCGG+LTG SG ILSPN+P PY
Sbjct: 1445 TVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPY 1504
Query: 1466 PPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIE 1525
P ++CDW +TV+ DYVI+L F F++EP YDFL+IYDG DS SPLIGSF S+LP RIE
Sbjct: 1505 PHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIE 1564
Query: 1526 SSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYYCH 1585
SSSN++ LAFRSD SVS GF ++Y RESCFDPG+I NGTR+G D KLGS+VTYYC
Sbjct: 1565 SSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCD 1624
Query: 1586 GGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQIC 1645
GY ++G STL+CI+G DG+P WN P C APCG + GS+G VLSPNYP+NY+ G C
Sbjct: 1625 AGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNC 1684
Query: 1646 LYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQV 1705
+Y + VPK++VVFGQF FF T+L+DVVEV+DG +Q S LLSSLSGSH+GESLPL++ NQ+
Sbjct: 1685 VYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQI 1744
Query: 1706 LIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGY 1765
I+F++ G A+GFHFVYQAVPRTS+TQCSSVPEPR+G+R+G++F+VG+ V F+CN GY
Sbjct: 1745 TIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGY 1804
Query: 1766 ALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWK 1825
L GS I C VP +LAQWN S PTC+VPCGG LT+R+GTILSPG+PEPY N+LNCVWK
Sbjct: 1805 ILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWK 1864
Query: 1826 IVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLH 1885
I VPEGAGIQ+QVVSF TE NWDSL+ +DG DN LGS+SGTT+P LLNSTSN LYL+
Sbjct: 1865 ITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLN 1924
Query: 1886 FYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHA 1945
F SDISVSAAGFHLEY +GL SCPEP PS+G+K G+RY+V DVVSFQC+ GY+LQGH+
Sbjct: 1925 FQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHS 1984
Query: 1946 HISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFG 2005
HI+CMPG VRRWNYP P+C+AQCGG + + GVILSPGFPGNYPS++DC+W I LP+GFG
Sbjct: 1985 HITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFG 2044
Query: 2006 AHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQN 2065
H+QF+NFSTE HDY+E+R+G ETS ++GR SG ++PSSL ST+HET++YFHSD+SQN
Sbjct: 2045 VHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQN 2104
Query: 2066 RPGFKLEYQDLTYSHQISSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPD 2125
+ GF + YQ AY+LQ CPD
Sbjct: 2105 KQGFHIVYQ------------------------------------------AYQLQSCPD 2122
Query: 2126 PEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGN 2185
P PF NG V G + VGQ+++FEC PGY L G+ LTC HG +RNW+HPLP+CE CGGN
Sbjct: 2123 PRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGN 2182
Query: 2186 ITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQT 2245
IT+ NGT+YSPG+P Y + QDC WL+ VP G+G+ +N ++LQTEP DFIT+WDGP Q
Sbjct: 2183 ITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQN 2242
Query: 2246 APRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILPNAEV 2305
+P++G F+ + A ++V S+SNQ+L+KFH D T G F +++ AY L C PP +PNAE+
Sbjct: 2243 SPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEI 2302
Query: 2306 VTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDST 2365
+TE++EF IGDI+RY+CLPGFTLVGN ILTC+LG LQ +G PP+C+V CP NEL DST
Sbjct: 2303 LTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDST 2362
Query: 2366 GVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLK 2425
GVILS YP SYP Q C+W + VE YNI++ VE+F +EK++D +++DGP+ QSP+L
Sbjct: 2363 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLI 2422
Query: 2426 ALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAPLHGFILGQTST 2485
+LSG+YS+ +TS+ + V+L+WS+DH N+KGF+IRY A YCS P +P HG+I+ QT
Sbjct: 2423 SLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGG 2482
Query: 2486 QPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGK 2545
Q + + C+ G+RLVG S A+C + GYH W +P CQA+SCG+P+AP NG +
Sbjct: 2483 QLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTT 2542
Query: 2546 EYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGR 2605
+Y VGT+ Y C++GY L + TA C G WSN N P+CV ++C ++ + +G
Sbjct: 2543 DYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELP--TPPNGN 2600
Query: 2606 WRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPP 2665
TQ + + + CD G+ G V C ++G WS +S C CG +
Sbjct: 2601 ---KIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWS--ESETRCLAGHCGIPELIV 2655
Query: 2666 NGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNG 2725
NG IG Y T ++ CN G+ L+GS VR C + WSG C+ CG P + G
Sbjct: 2656 NGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYG 2715
Query: 2726 HINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPH--- 2782
+G +++ V + CN G+ + G + CQ + WS P C +V+C PG P +
Sbjct: 2716 RTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKR 2775
Query: 2783 -SQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHC-------------- 2827
S++ ++T G VV Y C L G+S +C +G W LP C
Sbjct: 2776 ESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNA 2835
Query: 2828 -------------------------------------SGTSVGVCGD-------PGIPAH 2843
SG+ GD PG P H
Sbjct: 2836 VLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGH 2895
Query: 2844 GIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNAR 2903
G R +F + +R++C+ G++L GS ERTC ANGSW+G QPEC + CGNPGT +N +
Sbjct: 2896 GSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGK 2955
Query: 2904 VVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLR 2963
V DG FSSS++Y C EGY +G R C+ NGTW+G+ P C +I+CGDPGIPANGLR
Sbjct: 2956 VFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLR 3015
Query: 2964 LGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKV 3023
G+D+ + V+Y C PGY ME + + +CT + TW+G P C+A+ C PP I NG++
Sbjct: 3016 YGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRL 3075
Query: 3024 VGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGRRED 3083
G++F WG S++Y C GY+LS PAV TC GNG+W+GE+PQC P FCGDPG+P++G+RE
Sbjct: 3076 EGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREG 3135
Query: 3084 RGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQN 3143
+ F Y+S VSFSC+ P +LVGS R CQ+DGTWSG+ P CI+PT T+C +PGVP+ G QN
Sbjct: 3136 KSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQN 3195
Query: 3144 NSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGA 3203
N+ G+QVGS V F C+KG+LLQGSTTRTCLP+LTWSG P+C+PH C+QPETP HANV
Sbjct: 3196 NTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVG 3255
Query: 3204 LDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRPI-----NTA 3258
+DLPS GYTLIY+CQ GF L GG+EHR C++D +WTGK PIC +G I A
Sbjct: 3256 MDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC----EAGSKILVKDPRPA 3311
Query: 3259 REPPLTQALIPGDVFAKNSLWKGAYEYQGKKQPAMLRVTGFQVANSKVNATMIDHSGVEL 3318
P + +P DVFA+N +WKG+Y ++G+KQP L VT F + +VNAT + +S +EL
Sbjct: 3312 LGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNAT-LSNSNMEL 3370
Query: 3319 HLAGTYKKEDFHLLLQVYQITGPVEIFMNKFKDDHWALDGHVSSESSGATFIYQGSVKGQ 3378
L+G YK ++ L+L++Y I P + K K+++WA+DG VS+E GAT+++QG ++G+
Sbjct: 3371 LLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGK 3430
Query: 3379 GFGQFGFQRLDLRLLESDPESIGRHFASNSSSVAAAILVPFIALIIAGFVLYLYKHRRRP 3438
+GQFG QRL L + E S H +NSSSVA AILVPF ALI AGF YLYK R P
Sbjct: 3431 DYGQFGLQRLGLNMSEGSNSSNQPH-GTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAP 3489
Query: 3439 KVPFNGYAGHENTNVRATFENPMYDRNIQPTDIMASEAEFTVSTVCTAV 3487
K + G + HEN N +A FENPMYD N + + A + ++TVCT V
Sbjct: 3490 KTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV 3538
Score = 1553 bits (4021), Expect = 0.0
Identities = 1000/3021 (33%), Positives = 1472/3021 (48%), Gaps = 248/3021 (8%)
Query: 17 HHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHR-IQLVFQSFALEE 75
H P + C L GP+GT SP FP+ Y + A C W ITA ++ IQ+ F+ F LE
Sbjct: 435 HRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEI 494
Query: 76 DFDVLSVFDGPP--QPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEV 133
+D L++ DG P + LTG +P IVS ++ + L L +D +V + GF Y+
Sbjct: 495 GYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKE 554
Query: 134 LPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPL 193
+ +CG+PG GI++G F+ D +R+ C GF L G + C ++ W +
Sbjct: 555 IEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ----WSANI 610
Query: 194 PSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGY 253
P C C G + SP +P Y NN +C WTI+++ G I L F DF LE +
Sbjct: 611 PICIFP--CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQF 668
Query: 254 DFLEVTGTEGSSL----WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQI 309
DFL V + FTGA +P+ + S+ + LRL F +D + RGF+ Y
Sbjct: 669 DFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYN----- 723
Query: 310 ELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTC 369
+ GHN CPDPGIP +R G +F+LGSS+ C
Sbjct: 724 ---------------------------TFGHNECPDPGIPINARRFGDNFQLGSSISVIC 756
Query: 370 NEGY-DLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNN 428
EG+ QG++ ITC+ + D WS P C A C H PSG+I SP +P Y ++
Sbjct: 757 EEGFIKTQGTETITCI-LMDGKVMWSGLIPKCGAP-CGGHFSAPSGVILSPGWPGYYKDS 814
Query: 429 AHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIV 488
+C W+I A P IK+ FE F E YD L V DG +L GT VP +
Sbjct: 815 LNCEWVIEA-EPGHSIKITFERFQTELNYDVLEVHDG--PNLLSPLLGSYNGTQVPQFLF 871
Query: 489 STNHQMWLLFQTDGSGSSLGFKASYEEIEQG--SCGDPGIPAYGRREGSRFHHGDTLKFE 546
S+++ ++LLF TD S S+ GFK YE + SC DPGIP +GRR G F G T+ F
Sbjct: 872 SSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFS 931
Query: 547 CQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVW 606
C + L ++ + C+KN+ WS P C C + PSG +LSP YPE Y N L+C W
Sbjct: 932 CDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTW 991
Query: 607 LILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSS---GHV 663
+ + F+ +E D+L+I + + P L +G+ LP +I +
Sbjct: 992 TVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQP-LARLTGSDLPPTINAGLYGNFR 1050
Query: 664 ARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLG 723
A+L F +D S GFNITF+ + C DPG+P G R G + +G +++F C G+
Sbjct: 1051 AQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYR- 1109
Query: 724 TQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIE 783
+G+ I C L G VW++ + RC A CG T+ G +LSP +P Y++ C + I+
Sbjct: 1110 LEGTSEIIC-LGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQ 1168
Query: 784 AQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQF-LISTSNYLYLLF 842
Q G I I+ F D L++ DG+ + L+G + G + L STSN L+L F
Sbjct: 1169 VQAGKGINISARTFHLAQG-DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEF 1227
Query: 843 STDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGND-FYVGALVTFSCDSGYTLSD 901
++D +D GFQL Y + L HC DPGIP G + + + G+ + + C+ GYTL
Sbjct: 1228 NSDTEGTDEGFQLVYTSFELS--HCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHG 1285
Query: 902 GEPLECEPNFQ--WSRALPSCEALCGGFIQG-SSGTILSPGFPDFYPNNLNCTWIIETSH 958
L+C + W LPSC A CGG +G SSG ILSPG+P Y NNL C W+IE
Sbjct: 1286 SSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDP 1345
Query: 959 GKGVFFTFHTFHLESGHDYLLITENGSFTQPL-RQLTGSRLPAPISAGLYGNFTAQVRFI 1017
G V F F E+ HD L + + L ++++GS +P I + L ++F
Sbjct: 1346 GNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLN---IVTIQFD 1402
Query: 1018 SDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARI 1077
+DF +S GF I FS C +P VP R G GDT+ F C PGY L+G RI
Sbjct: 1403 TDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERI 1462
Query: 1078 TCLGGRRR-LWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGI 1136
TC+ R W P C+A CG ++TG+ G +LSPNFP Y ++ +C ++I I
Sbjct: 1463 TCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVI 1522
Query: 1137 QLKARAFELSEG-DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENT 1195
L +F + D L +YDG ++++ L+G F S++ + S+S+++ L F +D +
Sbjct: 1523 SLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE-RIESSSNTMHLAFRSDGSVS 1581
Query: 1196 SKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSG 1255
GF L + + C DPG G ++ + + GS+V++ CD GY L+G L C+ G
Sbjct: 1582 YTGFHLEYKAKLRESCFDPGNIMNGTRLGMD-YKLGSTVTYYCDAGYVLQGYSTLTCIMG 1640
Query: 1256 E--RRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLH 1313
+ R W+R LP+C A CG G G VLSP YP Y NC+++I +
Sbjct: 1641 DDGRPGWNRALPSCHAPCGSRSTGS-EGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQ 1699
Query: 1314 FLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLH-STFNSVVLQFSTDFFTSKQG 1372
F+ F T +HDV+ ++DGP + LL LSG + L S+ N + ++F++ + +G
Sbjct: 1700 FVFFQTS-LHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKG 1758
Query: 1373 FAIQFSV---STATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIE 1429
F + +++T C+ P+ G R G+ + G S +F C+PGY L GS I C +
Sbjct: 1759 FHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVP 1818
Query: 1430 NRFF-WQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFN 1488
N W S PTCI PCGG LT G ILSP YPEPY C WK+TV I +
Sbjct: 1819 NSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV 1878
Query: 1489 IFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVI 1548
F E +D L YDG D+ +P +GS+ G+ +P + S+SN+L+L F+SD SVS AGF +
Sbjct: 1879 SFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHL 1938
Query: 1549 DYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVW 1608
+YT +SC +P + +G ++G +G V++ C GY ++G S ++C+ GP + W
Sbjct: 1939 EYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRR--W 1996
Query: 1609 NNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHT-A 1667
N P P+C A CGG GV+LSP +P NY S C + + +P + V QF F T
Sbjct: 1997 NYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET 2056
Query: 1668 LNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAV 1727
++D +EV G S+ S ++ LSG SL +T+++ + F + +GFH VYQA
Sbjct: 2057 IHDYLEVRSGSSETSTVIGRLSGPQIPSSL-FSTTHETSLYFHSDYSQNKQGFHIVYQAY 2115
Query: 1728 PRTSATQCSSVPEPR---YGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQ 1784
Q S P+PR G +G+DF+VG + FEC GY L G+ + CL G
Sbjct: 2116 ------QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLH--GVSRN 2167
Query: 1785 WNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTE 1844
WN P C CGGN+T GTI SPG+P+ Y N +C W + VP G GI I TE
Sbjct: 2168 WNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTE 2227
Query: 1845 QNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 1904
+D + V+DG D +G FSG T + STSNQ+ + F+SD + S F L Y
Sbjct: 2228 PIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGF-FVLSYHAY 2286
Query: 1905 GLSSC-PEPAVPSNGVKT-GERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPP 1962
L C P P VP+ + T + + + D++ +QC PG+ L G+A ++C G + + PP
Sbjct: 2287 QLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPP 2346
Query: 1963 LCIAQCGGTVEEME--GVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHD 2020
+C C ++ GVILSPG+P +YP+ C+W I++ G+ + F TE D
Sbjct: 2347 VCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFD 2406
Query: 2021 YIEIRNGPYETSRMMGRFSGSELPS-SLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYS 2079
+++ +GP S ++ SG + ++ S HE + + +DH N+ GF++ Y S
Sbjct: 2407 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2466
Query: 2080 ---------------HQISSFL-----RGFDLSELERTNSTPPVAASYVWDLD-PGCEAY 2118
Q++S + RGF L + WD P C+A
Sbjct: 2467 TPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI 2526
Query: 2119 ELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWD--HPLP 2176
C P+ NG + Y VG VT+ C GY+L+ + T ++ W + P
Sbjct: 2527 ---SCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTP 2583
Query: 2177 KCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFI 2236
+C V ++ L T P+G+ I
Sbjct: 2584 RCVV-----------------------------------------ISCGELPTPPNGNKI 2602
Query: 2237 TIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPP 2296
G Q + +FT + V S+ R+ + G+++ + + C
Sbjct: 2603 ----GTQTSYGSTAIFTCDLGFMLVGSAV--------RECLSSGLWSESETRCLAGHCGI 2650
Query: 2297 PTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCP 2356
P ++ N +V+ EN + D V Y+C PGF L+G+ + C+ + G P C
Sbjct: 2651 PELIVNGQVIGEN--YGYRDTVVYQCNPGFRLIGSSVRICQQDH--NWSGQLPSC----- 2701
Query: 2357 TNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDG 2416
V +S +PGS +T S + Y + + +
Sbjct: 2702 ----------VPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ 2751
Query: 2417 PSGQSPLLKALS------------------GNYSAPLIVTSSSNSVYLRWSSDHAYNRKG 2458
S P+ K ++ GN++ +V N Y + S +
Sbjct: 2752 WSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPN 2811
Query: 2459 FKIRYSAPYCSL-----PRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHP 2513
+ P C + P P + + G+ T G ++H+ C L+G S C +
Sbjct: 2812 GQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTF-GSTVHYSCTGKRSLLGQSSRTCQLNG 2870
Query: 2514 QGYHLWSEAIPLCQ---ALSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEAT 2570
WS + P C +CG P P +G + + Y+C GY L E T
Sbjct: 2871 H----WSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERT 2926
Query: 2571 AECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYY 2630
CL G W+ R P+C V C + + + +G+ I T F + ++ C GY
Sbjct: 2927 --CLANGSWTGRQ--PECKAVQCGNPGTTA--NGKVFRIDGT--TFSSSVIYSCMEGYIL 2978
Query: 2631 TGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYT- 2689
+G V +C ANG WS + P C IISCG+ IP NG R G V G + C GYT
Sbjct: 2979 SGPSVRQCTANGTWS--GTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTM 3036
Query: 2690 -LVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRL 2748
L GSR+R C NG WSG C A C TP I NG + G N+ + S+ Y C+ G+ L
Sbjct: 3037 ELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYEL 3096
Query: 2749 IGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVG 2808
+V C + WSG+ P C+ CG PG P + G S+ + V +SC LVG
Sbjct: 3097 SFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVG 3156
Query: 2809 NSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGD-SFDPGTVMRFSCEAGHVL 2867
+STR+C DG W+GS PHC + C +PG+P HG + F G+V++F C+ GH+L
Sbjct: 3157 SSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLL 3216
Query: 2868 RGSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYY-A 2926
+GS+ RTC + +WSG QPEC SC P TP++A VV D +++Y C+ G++ A
Sbjct: 3217 QGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLA 3276
Query: 2927 TGLLSRHCSVNGTWTGSDPEC 2947
G R C + TWTG P C
Sbjct: 3277 GGTEHRVCRSDNTWTGKVPIC 3297
Score = 1226 bits (3172), Expect = 0.0
Identities = 863/2841 (30%), Positives = 1288/2841 (45%), Gaps = 277/2841 (9%)
Query: 573 GCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFL 632
G +++C +G + SP +P Y N +C W+I+A +RI + F +E ++D+L
Sbjct: 60 GFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYL 119
Query: 633 VIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECP 692
+ DG +G LP +TS+ V L +D + GF + + + + C
Sbjct: 120 SLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
Query: 693 DPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKE-GSVVWNSAV--LRCE 749
+PGVP G +G +G I + C G++ G +TC+ + W+ V R E
Sbjct: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYI-LDGHPQLTCIANSVNTASWDFPVPICRAE 238
Query: 750 APCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVR 809
CGG + SG I SP +P Y + C W I A+PG I + F F+ E YD LE+
Sbjct: 239 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 298
Query: 810 DGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYET---------- 859
S P G +P +IS N+L L F TD +H GF Y+
Sbjct: 299 G----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRG 354
Query: 860 --------------------ITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTL 899
I S+ C DPG P NG+R G+DF +G+ V FSCD Y L
Sbjct: 355 FKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVL 414
Query: 900 SDGEPLEC----EPNFQWSRALPSCEA-LCGGFIQGSSGTILSPGFPDFYPNNLNCTWII 954
+ + C E WS P C+ CG +QG SGT SP FP Y +N C W+I
Sbjct: 415 QGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVI 474
Query: 955 -ETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQP---LRQLTGSRLPAPISAGLYGNF 1010
+ K + F F LE G+D L I + G P L+ LTGS +P L +
Sbjct: 475 TAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVP-----DLIVSM 529
Query: 1011 TAQ--VRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPG 1068
++Q + +D S+ GF + + E + E C +P P Y IR+G F D L F C G
Sbjct: 530 SSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFG 589
Query: 1069 YRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSI 1128
+ L G I C + WS+ +P C+ C ++ T GT+LSP++P Y NN CI++I
Sbjct: 590 FELIGEKSIVCQENNQ--WSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTI 647
Query: 1129 QTQPGKGIQLKARAFEL-SEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLD 1187
+ PG I L F+L S+ D L V DG++ + +LG F+ +E+ L S S L L+
Sbjct: 648 ISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPS-HLTSNSHILRLE 706
Query: 1188 FITDAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGY-SLRG 1246
F D + +GF + +++F +C DPG P + D GSS+S C+ G+ +G
Sbjct: 707 FQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQL-GSSISVICEEGFIKTQG 765
Query: 1247 SEELLCLSGERRT-WDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAE 1305
+E + C+ + + W +P C A CGG SG +LSPG+P Y+ +LNC W IEAE
Sbjct: 766 TETITCILMDGKVMWSGLIPKCGAPCGGHFSAP-SGVILSPGWPGYYKDSLNCEWVIEAE 824
Query: 1306 AGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTD 1365
G +I + F F TE +DVL + DGP LL +G +P+ L S+ N + L F+TD
Sbjct: 825 PGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTD 884
Query: 1366 FFTSKQGFAIQFSVSTAT--SCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEI 1423
S GF I + T SC DPGIP +G R G + G + F CD GY L +
Sbjct: 885 NSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPL 944
Query: 1424 SCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVI 1483
C E +W PTC A CGGD+ GPSG ILSP YPE YP C W V V+ +
Sbjct: 945 LC---EKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1001
Query: 1484 ALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLF---LAFRSDAS 1540
F+ F+LE +D+L I + PL GS LP I + F L F SD S
Sbjct: 1002 QFNFHTFHLEDHHDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFS 1060
Query: 1541 VSNAGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCIL 1600
+S GF I ++E E C DPG + G+R+G + +G ++T+ C GY +EGTS + C+
Sbjct: 1061 ISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLG 1120
Query: 1601 GPDGKPVWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQ 1660
G G+ VW+ P P C A CG ++G++LSPNYP NY + C+Y + V +
Sbjct: 1121 G--GRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINIS 1178
Query: 1661 FAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGF 1720
FH A DV++++DG + + LL + +G+ +TSNQ+ ++F++ GF
Sbjct: 1179 ARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGF 1238
Query: 1721 HFVYQAVPRTSATQCSSVPEPRYGKRLGSD-FSVGAIVRFECNSGYALQGSPEIECLPVP 1779
VY + + C P++G ++ G+ + + CN GY L GS ++C+
Sbjct: 1239 QLVYTSF---ELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCM--T 1293
Query: 1780 GALAQWNVSAPTCVVPCGGNLT-ERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQV 1838
G W+ P+C+ CGG E G ILSPG+P PY N+L C+W I V G + +Q
Sbjct: 1294 GERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQF 1353
Query: 1839 VSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFH 1898
++F TE + D L V+DG +L SG+ +P ++ST N + + F +D +S +GF
Sbjct: 1354 LAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFA 1413
Query: 1899 LEYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRR-W 1957
+++ + ++C +P VP NG + G+ D V FQC+PGY LQG I+C+ R W
Sbjct: 1414 IQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFW 1473
Query: 1958 NYPPPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEP 2017
PP+CIA CGG + G ILSP FP YP + DC W I + + + F++FS EP
Sbjct: 1474 QPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEP 1533
Query: 2018 NHDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLT 2077
N+D++ I +GP S ++G F S+LP + S+S+ + F SD S + GF LEY
Sbjct: 1534 NYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEY---- 1589
Query: 2078 YSHQISSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGA 2137
+A + C DP NG G
Sbjct: 1590 --------------------------------------KAKLRESCFDPGNIMNGTRLGM 1611
Query: 2138 GYNVGQSVTFECLPGYQLTGHPVLTCQHGTN--RNWDHPLPKCEVPCGGNITSSNGTVYS 2195
Y +G +VT+ C GY L G+ LTC G + W+ LP C PCG T S GTV S
Sbjct: 1612 DYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLS 1671
Query: 2196 PGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRS 2255
P +P YS +CV+ I VP V QT D + ++DGP Q + L + S
Sbjct: 1672 PNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTS-LHDVVEVYDGPTQQSSLLSSLSGS 1730
Query: 2256 MAKKTVQ-SSSNQVLLKFHR-DAATGGIFAIAFSAYPLTKCPPPTILPNAEVVTE-NEEF 2312
+ +++ SS NQ+ ++F T F + A P T + +P EF
Sbjct: 1731 HSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEF 1790
Query: 2313 NIGDIVRYRCLPGFTLVGNEILTCKL--GTYLQFEGPPPICEVHCPTNELLTDSTGVILS 2370
+G V + C PG+ L G+ + C+ + Q+ P C V C +LT G ILS
Sbjct: 1791 AVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPC--GGILTKRKGTILS 1848
Query: 2371 QSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGN 2430
YP Y C W + V I + V F +E +D + +DG +P L + SG
Sbjct: 1849 PGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGT 1908
Query: 2431 YSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA---PYCSLPRAPLHGFILGQTSTQP 2487
+ P ++ S+SN++YL + SD + + GF + Y+A C P+ P G +G
Sbjct: 1909 -TIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGD-RYMV 1966
Query: 2488 GGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGKEY 2547
G + F C+ GY L GHS C P W+ IP+C A CG + +G++ +
Sbjct: 1967 GDVVSFQCDQGYSLQGHSHITCM--PGPVRRWNYPIPICLA-QCGGAMSDFSGVILSPGF 2023
Query: 2548 TVGTKAMYSCS--------EGYHLQAGAEATAECLD-----TGLWSNRNVPPQCVPVTCP 2594
+ C+ G HLQ +T D +G V + P
Sbjct: 2024 PGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIP 2083
Query: 2595 DVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCR 2654
S S H L F + Y Q G++ Q +
Sbjct: 2084 S-SLFSTTH-ETSLYFHSDYSQNKQ-------GFHIVYQ------------------AYQ 2116
Query: 2655 IISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECM--ANGLWSGSEVRCL 2712
+ SC + NG IG G T F C GYTL+G+ C+ + W+ RC
Sbjct: 2117 LQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2176
Query: 2713 AGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRL-----IGMSVRICQQDHHWSGKTP 2767
A CG +NG I Y C R+ I ++ + Q + +
Sbjct: 2177 A-LCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYD---- 2231
Query: 2768 FCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHC 2827
F + SP Q SG++ YS + + +S G + S
Sbjct: 2232 FITVWDGPDQNSPQIGQFSGNTALESV---YSTSNQILIKFHSD--FTTSGFFVLSY--- 2283
Query: 2828 SGTSVGVC-GDPGIP-AHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANG--SWSG 2883
+ VC P +P A + D F+ G ++R+ C G L G++ TC+ G
Sbjct: 2284 HAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDG 2343
Query: 2884 SQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYEC------REGYYATGLLSRH---- 2933
+ P C V+ N + V+ S G S + C +GY T +
Sbjct: 2344 APPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK 2403
Query: 2934 ------------------CSVNGTW------TGSDPECLVINCGDPGIPANGLRLGNDFR 2969
S++G + T + E + D G G R+
Sbjct: 2404 EFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAF 2463
Query: 2970 YNKT--------------------VTYQCVPGYMM--ESHRVSVLSCTKDRTWNGTKPVC 3007
Y T V + C G+ + +S V S W+ P C
Sbjct: 2464 YCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2523
Query: 3008 KALMCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFT--CEGNGSWT--GELP 3063
+A+ C P NG ++ +D++ G+ VTY C +GY+LS + T C+ +G+W+ + P
Sbjct: 2524 QAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTP 2583
Query: 3064 QCFPVFCGDPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSC 3123
+C + CG+ P G + SY S+ F+C +LVGS R C S G WS ++ C
Sbjct: 2584 RCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2643
Query: 3124 IDPTLTTCADPGVPQFGIQNN--SQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGT 3181
+ G+P+ + + Y TV+++C G+ L GS+ R C + WSG
Sbjct: 2644 L------AGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQ 2697
Query: 3182 PPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGK 3241
P CVP C P +P + + + +SC G+ ++G ++ + C+A+ W+
Sbjct: 2698 LPSCVPVSCGHPGSPIYGRTSGNGF-NFNDVVTFSCNIGYLMQGPTKAQ-CQANRQWSHP 2755
Query: 3242 PPICLEVRPS--GRPINTARE 3260
PP+C V S G P N+ RE
Sbjct: 2756 PPMCKVVNCSDPGIPANSKRE 2776
Score = 935 bits (2417), Expect = 0.0
Identities = 689/2370 (29%), Positives = 1068/2370 (45%), Gaps = 267/2370 (11%)
Query: 16 SHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEE 75
SH + C + GP+GT+ SPG+P YPN NCTWT+ +Q F +F LE+
Sbjct: 953 SHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLED 1012
Query: 76 DFDVLSVFDGPPQPENLRTRLTGFQLPATI---VSAATTLSLRLISDYAVSAQGFHATYE 132
D L + + + L RLTG LP TI + LR ISD+++S +GF+ T+
Sbjct: 1013 HHDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1071
Query: 133 VLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFP 192
C +PG G + G F +GD + +SC+ G+ LEG + + C G W P
Sbjct: 1072 EYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRR--VWSAP 1129
Query: 193 LPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG 252
LP C A+ CG + GI+ SP++P Y NN +C ++I + G I + F L G
Sbjct: 1130 LPRCVAE--CGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG 1187
Query: 253 YDFLEVTGTEGSSLW----FTGASLPAPVISS-KNWLRLHFTSDGNHRQRGFSAQYQVKK 307
D L++ + + FTGAS+ +SS N L L F SD GF Y
Sbjct: 1188 -DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY---T 1243
Query: 308 QIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRL-GSSVQ 366
EL + C DPGIP+ G ++ GS++
Sbjct: 1244 SFEL-----------------------------SHCEDPGIPQFGYKISDQGHFAGSTII 1274
Query: 367 FTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRG-PSGIITSPNFPIQY 425
+ CN GY L GS + CM + AW P C A C +G SG I SP +P Y
Sbjct: 1275 YGCNPGYTLHGSSLLKCM--TGERRAWDYPLPSCIAE-CGGRFKGESSGRILSPGYPFPY 1331
Query: 426 DNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPD 485
DNN C+W+I ++P ++ L F FD E +D L V DG + D +L ++G+ +P+
Sbjct: 1332 DNNLRCMWMI-EVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDM--LLKEISGSLIPE 1388
Query: 486 LIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKF 545
I ST + + + F TD S GF + +C DPG+P G R G GDT+ F
Sbjct: 1389 GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVF 1448
Query: 546 ECQPAFELVGQKAITC-QKNNQ--WSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHL 602
+C P +EL G++ ITC Q N+ W P C+ C N T SG +LSPN+P Y +
Sbjct: 1449 QCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSR 1508
Query: 603 HCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGH 662
C W I + I LAF +EP +DFL I DG + +P++G+F ++LP I SS +
Sbjct: 1509 DCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSN 1568
Query: 663 VARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFL 722
L F++D S GF++ + C DPG +NG R G +LGS++++ CD G++
Sbjct: 1569 TMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYV 1628
Query: 723 GTQGSETITCVL-KEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWV 781
QG T+TC++ +G WN A+ C APCG T GT+LSP +P Y +C +
Sbjct: 1629 -LQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYS 1687
Query: 782 IEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFL-ISTSNYLYL 840
I + + F F+T + +D +EV DG T + L+ G+ + L +S+ N + +
Sbjct: 1688 IAVPKEFVVFGQFVFFQTSL-HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITI 1746
Query: 841 LFSTDKSHSDIGFQLRYETI-TLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTL 899
F++ + GF Y+ + S C P G+R GN+F VG+ V F C+ GY L
Sbjct: 1747 RFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYIL 1806
Query: 900 SDGEPLECE--PN--FQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIE 955
+ CE PN QW+ +LP+C CGG + GTILSPG+P+ Y NNLNC W I
Sbjct: 1807 HGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKIT 1866
Query: 956 TSHGKGVFFTFHTFHLESGHDYLLITENGSFTQP-LRQLTGSRLPAPI---SAGLYGNFT 1011
G G+ +F E D L + G P L +G+ +P + S LY NF
Sbjct: 1867 VPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQ 1926
Query: 1012 AQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRL 1071
SD S+S GF++ ++ L+ C EP+ P+ I+ G ++ VGD ++F C GY L
Sbjct: 1927 ------SDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSL 1980
Query: 1072 EGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQ 1131
+G + ITC+ G R W+ P+P C+A+CG +++ G +LSP FP NY ++ +C ++I
Sbjct: 1981 QGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLP 2040
Query: 1132 PGKGIQLKARAFELSE-GDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFIT 1190
G G+ L+ F D L+V G++ ++ ++G S ++ +L ST+ L F +
Sbjct: 2041 IGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPS-SLFSTTHETSLYFHS 2099
Query: 1191 DAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEEL 1250
D +GF + + +++L C DP + G+ + ++ G ++SF C PGY+L G+ L
Sbjct: 2100 DYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGND-FTVGQTISFECFPGYTLIGNSAL 2158
Query: 1251 LCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTI 1310
CL G R W+ PLP C A CGG + ++G + SPGYP Y + +C W + G I
Sbjct: 2159 TCLHGVSRNWNHPLPRCEALCGGNITA-MNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGI 2217
Query: 1311 GLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSK 1370
++F V TE ++D + +WDGP ++ + + SG + ++ST N ++++F +DF TS
Sbjct: 2218 YINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS- 2276
Query: 1371 QGFAIQFSVSTATSCNDPGIPQNGS--RSGDSWEAGDSTVFQCDPGYALQGSAEISCVKI 1428
F + + C P N D +E GD +QC PG+ L G+A ++C ++
Sbjct: 2277 GFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTC-RL 2335
Query: 1429 ENRFFWQPSPPTC--IAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALV 1486
R +PP C + P +GVILSP YP+ YP + C W ++V Y I +
Sbjct: 2336 GERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMF 2395
Query: 1487 FNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPG-RIESSSNSLFLAFRSDASVSNAG 1545
F E +D L +YDG + SP++ S G I S+ + +FL + +D + G
Sbjct: 2396 VEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKG 2455
Query: 1546 FVIDYTENPRESCFDPGSIKNGTRVG-SDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDG 1604
F I Y C P S +G + + +L S V + C G+ + G S+ C G
Sbjct: 2456 FRIRYI---AFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYG 2512
Query: 1605 KPVWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFF 1664
W+ P P C A +S P+ T+G I + DY+V + +F
Sbjct: 2513 YHAWDAPVPACQA-------------ISCGIPKAPTNGGI------LTTDYLVGTRVTYF 2553
Query: 1665 HTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVY 1724
+DG+ S+ L++ + + G +
Sbjct: 2554 ---------CNDGYRLSSKELTT-------------------------AVCQSDGTWSNH 2579
Query: 1725 QAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQ 1784
PR C +P P G ++G+ S G+ F C+ G+ L GS ECL +
Sbjct: 2580 NKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECL----SSGL 2635
Query: 1785 WNVSAPTCVV-PCGGNLTERRGTILSP--GFPEPYLNSLNCVWKIVVPEGAGIQIQVVSF 1841
W+ S C+ CG G ++ G+ + + N ++++ G+ ++I
Sbjct: 2636 WSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLI---GSSVRI----C 2688
Query: 1842 VTEQNWDS-----LEVFDG-ADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAA 1895
+ NW + V G + + S +G ++ + N YL + A
Sbjct: 2689 QQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQA 2748
Query: 1896 GFHLEY--KTVGLSSCPEPAVPSNGVKTGE----RYLVNDVVSFQCEPGYALQGHAHISC 1949
+ + +C +P +P+N + + + VV + C PGY L G + + C
Sbjct: 2749 NRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLIC 2808
Query: 1950 MPGTVRRWNYPPPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQ 2009
P +W+ P P CI ++ G PG P+ + K FG+ +
Sbjct: 2809 QPN--GQWDKPLPECI-------------MIDCGHPGVPPNAVLSGEKYT----FGSTVH 2849
Query: 2010 FLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGF 2069
+ + T ++ G +SGS+ S +T S+ F
Sbjct: 2850 YSCTGKR------SLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNF 2903
Query: 2070 KLEYQDLTYSHQISSFLRGFDLSELERTNSTPPVAASYVW-DLDPGCEAYELQECPDPEP 2128
+ + + Y+ L G + ERT A+ W P C+A +C +P
Sbjct: 2904 RTK-STVRYACDTGYILHGSE----ERT-----CLANGSWTGRQPECKAV---QCGNPGT 2950
Query: 2129 FANG-IVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCE-VPCGGNI 2186
ANG + R G SV + C+ GY L+G V C N W LP C + CG
Sbjct: 2951 TANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCT--ANGTWSGTLPNCTIISCGDPG 3008
Query: 2187 TSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTA 2246
+NG Y + + S C G+ + LN S ++T W G T
Sbjct: 3009 IPANGLRYGDDYVVGQNVSYMC------QPGYTMELNGSRIRTCTING---TWSGVMPTC 3059
Query: 2247 PRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILPNAEVV 2306
+ CP P + N +
Sbjct: 3060 RAV-------------------------------------------TCPTPPQISNGRL- 3075
Query: 2307 TENEEFNIGDIVRYRCLPGFTLVGNEILTC 2336
E F+ G + Y C PG+ L +LTC
Sbjct: 3076 -EGTNFDWGFSISYICSPGYELSFPAVLTC 3104
Score = 263 bits (672), Expect = 2e-69
Identities = 258/955 (27%), Positives = 398/955 (41%), Gaps = 146/955 (15%)
Query: 4 ISIAPGP--RWQVQSHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQ 61
I+ PGP RW P Q C + +G + SPGFP YP+ +CTWTI
Sbjct: 1986 ITCMPGPVRRWNYPI--PICLAQ-CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIG 2042
Query: 62 HRIQLVFQSFALEEDFDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYA 121
+ L F +F+ E D L V G + + RL+G Q+P+++ S SL SDY+
Sbjct: 2043 FGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYS 2102
Query: 122 VSAQGFHATYEVLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHA 181
+ QGFH Y+ +C +P NG G+ F +G + + C G+ L G++ LTC
Sbjct: 2103 QNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLH 2162
Query: 182 GSENSATWDFPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIA 241
G S W+ PLP C A CGG + +G I SP +P EY N DC W + G+ I
Sbjct: 2163 GV--SRNWNHPLPRCEA--LCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIY 2218
Query: 242 LVFIDFQLEDGYDFLEV-TGTEGSSL---WFTGASLPAPVISSKNWLRLHFTSDGNHRQR 297
+ F Q E YDF+ V G + +S F+G + V S+ N + + F SD
Sbjct: 2219 INFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFT---- 2274
Query: 298 GFSAQYQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGS 357
++ + V + R + P N++ +LT+
Sbjct: 2275 --TSGFFVLSYHAYQLRVCQPPPPVPNAE---ILTE----------------------DD 2307
Query: 358 DFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAH-LR-GPSGI 415
+F +G +++ C G+ L G+ +TC + PVC+ +C A+ LR +G+
Sbjct: 2308 EFEIGDIIRYQCLPGFTLVGNAILTCRLGERL--QMDGAPPVCQV-LCPANELRLDSTGV 2364
Query: 416 ITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVL 475
I SP +P Y N C W I ++ I + E F E+ +D L V DG Q VL
Sbjct: 2365 ILSPGYPDSYPNLQMCAWSI-SVEKGYNITMFVEFFQTEKEFDVLQVYDG--PNIQSPVL 2421
Query: 476 YILTGT-SVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYG---R 531
L+G S I S H+++L + D + GF+ Y C P P +G
Sbjct: 2422 ISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCSTPESPPHGYIIS 2478
Query: 532 REGSRFHHGDTLKFECQPAFELVGQKAITCQKN----NQWSAKKPGC-VFSCFFNFTSPS 586
+ G + + +++ C F LVG+ + C+K+ + W A P C SC +
Sbjct: 2479 QTGGQLN--SVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTN 2536
Query: 587 GVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLG 646
G +L+ +Y +R+ ND L K+ TA G
Sbjct: 2537 GGILTTDY----------------LVGTRVTYFCND------GYRLSSKELTTAVCQSDG 2574
Query: 647 TFSG-NQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGD 705
T+S N+ P + S C + P NG + G
Sbjct: 2575 TWSNHNKTPRCVVIS------------------------------CGELPTPPNGNKIGT 2604
Query: 706 SLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEA-PCGGHLTSPSGTIL 764
GS+ F CD GF+ GS C+ S +W+ + RC A CG +G ++
Sbjct: 2605 QTSYGSTAIFTCDLGFM-LVGSAVRECL---SSGLWSESETRCLAGHCGIPELIVNGQVI 2660
Query: 765 SPGWPGFYKDALSCAWVIEAQPGYPIKITFDRF-KTEVNY-----DTLEVRDGRTYSAPL 818
+ Y+D + V + PG+ + + R + + N+ + V G +P+
Sbjct: 2661 GENYG--YRDTV----VYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHP-GSPI 2713
Query: 819 IG--VYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNG 876
G +G + + N YL+ K+ Q + + +C DPGIP N
Sbjct: 2714 YGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANS 2773
Query: 877 QR-----HGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEAL-CG 925
+R HGN F G +V + C+ GY L L C+PN QW + LP C + CG
Sbjct: 2774 KRESKIEHGN-FTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCG 2827
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 4341 bits (11259), Expect = 0.0
Identities = 2006/3239 (61%), Positives = 2475/3239 (76%), Gaps = 70/3239 (2%)
Query: 23 GQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSV 82
GQNC + GPNGT+ESPGFP+GYPNYANCTW I E++RIQL F +FALEEDFD+LSV
Sbjct: 29 GQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSV 88
Query: 83 FDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNP 142
+DG PQ NL+ RL+GFQLP++IVS + L+L +D+AVSAQGF A YEVLPSHTCGNP
Sbjct: 89 YDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNP 148
Query: 143 GRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDAC 202
G + G+ G+ FN+GDK+RYSC G+ LEGHA+LTC N A+WDFP P CRA+ AC
Sbjct: 149 GEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGAC 208
Query: 203 GGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTE 262
GGTLRG S ISSPHFPSEY NNADCTWTILAE GDTIALVF DFQLE+GYDFLE++GTE
Sbjct: 209 GGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEISGTE 268
Query: 263 GSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVKLMPSK 322
S+W TG +LP+PVISSKNWLRLHFTSD NHR++GF+AQ+QVKK IELKSRGVK++PSK
Sbjct: 269 APSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVKMLPSK 328
Query: 323 DNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDF-RLGSSVQFTCNEGYDLQGSKRI 381
D S K SVL+Q GV+ +MCPDPGIPE G+R GSDF R+G++VQF+C + Y LQGSK I
Sbjct: 329 DGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSI 388
Query: 382 TCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPS 441
TC +V++ AAWSDHRP+CRAR C ++LRGPSG+ITSPN+P+QY++NAHCVW+IT +P
Sbjct: 389 TCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPD 448
Query: 442 KVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTD 501
KVIKLAFEEF+LERGYDTLTVGD G+ GD ++VLY+LTG+SVPDLIVS ++QMWL Q+D
Sbjct: 449 KVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSD 508
Query: 502 GSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITC 561
S S GFKA Y+EIE+G CGDPGIPAYG+R GS F HGDTL FEC AFELVG++ ITC
Sbjct: 509 DSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITC 568
Query: 562 QKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFN 621
Q+NNQWS KP CVFSCFFNFT+ SG++LSPNYPE+YGN+++CVWLI++ P SRIHL FN
Sbjct: 569 QQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFN 628
Query: 622 DIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNI 681
D DVEPQFDFL +KD ++ VLGTFSGN++PS + SSGH+ RLEFQ+DHST RGFNI
Sbjct: 629 DFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNI 688
Query: 682 TFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVW 741
T+TTF NEC DPG+P+NG+RFGD LGSS+SF CD+GF+ TQGSE+ITC+L++G+VVW
Sbjct: 689 TYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVW 748
Query: 742 NSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEV 801
+S V RCEAPCGGHLT+ SG IL PGWPG+YKD+L C W+IEA+PG+ IKITFDRF+TEV
Sbjct: 749 SSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEV 808
Query: 802 NYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETIT 861
NYDTLEVRDG S+PLIG YHGTQ PQFLIST N++YLLF+TD S S IGF + YE++T
Sbjct: 809 NYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVT 868
Query: 862 LQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCE 921
L+SD CLDPGIPVNG RHG DF + + VTFSCD GYTLSD EPL CE N QW+ ALPSC+
Sbjct: 869 LESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCD 928
Query: 922 ALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLIT 981
ALCGG+IQG SGT+LSPGFPDFYPN+LNCTW IE SHGKGV FHTFHLES HDYLLIT
Sbjct: 929 ALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLIT 988
Query: 982 ENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCEE 1041
E+GSF++P+ +LTGS LP I AGL+GNFTAQ+RFISDFS+SYEGFNITFSEYDLEPC++
Sbjct: 989 EDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYDLEPCDD 1048
Query: 1042 PEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNS 1101
P VPA+S R G FGVGD+LTFSCF GYRLEG ++TCLGG RR+WS+PLPRCVAECG S
Sbjct: 1049 PGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGAS 1108
Query: 1102 VTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSA 1161
V G +GTLLSPNFP NY+NNHECIY I+T+ GKGI L+ R+F+L EGD LKVYDG ++S+
Sbjct: 1109 VKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVYDGKDSSS 1168
Query: 1162 RLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCEDPGTPKFGY 1221
R LG F+ +E++G+ LNSTS+ LWL+F T+ +T +GF+L ++SF+L+KCEDPG P +GY
Sbjct: 1169 RPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGY 1228
Query: 1222 KVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECGGTVRGEVSG 1281
++ DEGHF + V +SC+PGY++ GS L CLSG+RR WD+PLP+C+AECGG + SG
Sbjct: 1229 RIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSG 1288
Query: 1282 QVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKE 1341
++LSPGYPAPY++NL+C W IEA+ G TI LHF+VFDTE HD+L++WDGPV+S +LLKE
Sbjct: 1289 RILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKE 1348
Query: 1342 LSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQNGSRSGDSW 1401
SG ALP+D+HSTFNS+ LQF +DFF SK GF+IQFS S A +CNDPG+PQNG+R GDS
Sbjct: 1349 WSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSR 1408
Query: 1402 EAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNY 1461
EAGD+ FQCDPGY LQG A+I+CV++ NRFFWQP PPTCIA CGG+LTGP+GVILSPNY
Sbjct: 1409 EAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNY 1468
Query: 1462 PEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLP 1521
P+PYPPGKECDW+V V+PD+VIAL+F FN+EP YDFLHIY+G DS SPLIGS+ GSQ P
Sbjct: 1469 PQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAP 1528
Query: 1522 GRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSVT 1581
RIESS NSLFLAFRSDASV +GF I++ E PRE+CFDPG+I NGTRVG+D KLGS++T
Sbjct: 1529 ERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDPGNIMNGTRVGTDFKLGSTIT 1588
Query: 1582 YYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTS 1641
Y C GY++ S+++C++G DGKP W+ P C APCGGQY GS+GVVLSPNYP NYT+
Sbjct: 1589 YQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTA 1648
Query: 1642 GQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLAT 1701
GQICLY +TVPK++VVFGQFA+F TALND+ E+ DG +RLLSSLSGSH+GE+LPLAT
Sbjct: 1649 GQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLSSLSGSHSGETLPLAT 1708
Query: 1702 SNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFEC 1761
SNQ+L++FSAK A ARGFHFVYQAVPRTS TQCSSVPEPRYG+R+GS+FS G+IVRFEC
Sbjct: 1709 SNQILLRFSAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFEC 1768
Query: 1762 NSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLN 1821
N GY LQGS + C VP ALAQWN + P+CVVPC GN T+RRGTILSPG+PEPY N+LN
Sbjct: 1769 NPGYLLQGSTALHCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLN 1828
Query: 1822 CVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQ 1881
C+WKI+V EG+GIQIQV+SF TEQNWDSLE+ DG D T LGSFSGTTVPALLNSTSNQ
Sbjct: 1829 CIWKIIVTEGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQ 1888
Query: 1882 LYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYAL 1941
LYLHF SDISV+AAGFHLEYKTVGL++C EPA+PSN +K G+RY+VNDV+SFQCEPGY L
Sbjct: 1889 LYLHFQSDISVAAAGFHLEYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTL 1948
Query: 1942 QGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALP 2001
QG +HISCMPGTVRRWNYP PLCIA CGGT+ + GVILSPGFPG+YP+N+DC+W+I+LP
Sbjct: 1949 QGRSHISCMPGTVRRWNYPSPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLP 2008
Query: 2002 VGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSD 2061
+G+GAHIQFLNFSTE NHD++EI+NGPY TS M+G+FSG++LP++LLST+HET ++F+SD
Sbjct: 2009 IGYGAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSD 2068
Query: 2062 HSQNRPGFKLEYQDLTYSHQISSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQ 2121
HSQNR GFKL YQ AYELQ
Sbjct: 2069 HSQNRQGFKLAYQ------------------------------------------AYELQ 2086
Query: 2122 ECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVP 2181
CPDP PF NG + + Y+VGQSV+FEC PGY L GHPVLTCQHG NRNW++P P+C+ P
Sbjct: 2087 NCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAP 2146
Query: 2182 CGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDG 2241
CG N+TS NGT+YSPGFP Y +DC+WLITVP GHGV +N +LLQTE D+I +WDG
Sbjct: 2147 CGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDG 2206
Query: 2242 PQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILP 2301
P Q +P+LGVF+ + A +T SS+NQVLLKFH D + GG F + F A+ L KC PP +P
Sbjct: 2207 PDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPPPAVP 2266
Query: 2302 NAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELL 2361
AE++TE+++F IGD V+Y+C PG+TLVG +ILTCKL + LQFEG P CE CP NE+
Sbjct: 2267 QAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVR 2326
Query: 2362 TDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQS 2421
T S+GVILS YPG+Y QTCSW ++VEP+YNI++ V+ F SEKQ+D E+FDG SGQS
Sbjct: 2327 TGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQS 2386
Query: 2422 PLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAPLHGFILG 2481
PLL LSGN++ TS SN +YLRWS+DHA ++KGFKIRY+APYCSL +G IL
Sbjct: 2387 PLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTHPLKNGGILN 2446
Query: 2482 QTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGM 2541
+T+ G +H+ C GYR+VGHS A C R+P G + W PLCQA+SCG+PE+P NG
Sbjct: 2447 RTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGS 2506
Query: 2542 VFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISV 2601
G E+T+ +K +Y C EG+ L++ +ATA C + GLWSN+ PP C PV CP + +
Sbjct: 2507 FTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLS 2566
Query: 2602 EHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGEL 2661
EH WRL+ + ++ AQ++L C PGYY G R++RCQANG W++GD P+CR+ISCG L
Sbjct: 2567 EHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSL 2626
Query: 2662 PIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEP 2721
PPNG++IGTL+VYGATAIF+CN+GYTLVGS VREC+ANGLWSGSE RCLAGHCG+P+P
Sbjct: 2627 SFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDP 2686
Query: 2722 IVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPP 2781
IVNGHI+G+ +SYR +VVYQCN GFRL+G SVRIC QDH WSG+TP CV ++CGHPG+P
Sbjct: 2687 IVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPA 2746
Query: 2782 HSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIP 2841
H +G + + VV ++C L G S C +G W+ LP C V C DPG
Sbjct: 2747 HGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC---RVVNCSDPGFV 2803
Query: 2842 AHGIRLG-----DSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNP 2896
+ IR G +SF+ G + + C+ G L GSS TC ANG W S P+C ISCG+P
Sbjct: 2804 ENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHP 2863
Query: 2897 GTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVIN---CG 2953
G P+NA V+ + + + + Y CR G +R C + W+G+ P C N CG
Sbjct: 2864 GVPANA-VLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCG 2922
Query: 2954 DPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCK 3013
DPG PA+G RLG+DF+ + + C G+ + +C + +W+G +PVC+A+ C
Sbjct: 2923 DPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGS--PERTCLLNGSWSGLQPVCEAVSCG 2980
Query: 3014 PPPLIPNGKVVGSD-FMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGD 3072
P NG +V SD ++ SSV YAC EGY+ S C NG+WTG P C + CGD
Sbjct: 2981 NPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGD 3040
Query: 3073 PGVPSRGRREDRGFSYRSSVSFSCHPPLVL--VGSPRRFCQSDGTWSGTQPSCIDPTLTT 3130
PG + G + F++ +VS+ C+P V+ V S C DG W+ ++P C
Sbjct: 3041 PGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVC---KAVL 3097
Query: 3131 CADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHC 3190
C P Q G S ++ GS++ + C GY L S +C W G P C+P C
Sbjct: 3098 CPQPPPVQNGTVEGSD-FRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFC 3156
Query: 3191 RQPETPTHANVGALDLPSMGY--TLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLE 3247
P P G L S Y + + C+ F L GS R C+ADG+W+G P C++
Sbjct: 3157 GDPGIPAE---GRLSGKSFTYKSEVFFQCKSPFILV-GSSRRVCQADGTWSGIQPTCID 3211
Score = 1458 bits (3775), Expect = 0.0
Identities = 970/3035 (31%), Positives = 1433/3035 (47%), Gaps = 210/3035 (6%)
Query: 17 HHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHR-IQLVFQSFALEE 75
H P + C L GP+G + SP +P Y + A+C W IT + + I+L F+ F LE
Sbjct: 403 HRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELER 462
Query: 76 DFDVLSVFDGPP--QPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEV 133
+D L+V D ++ LTG +P IVS + + L L SD ++ + GF A Y+
Sbjct: 463 GYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQE 522
Query: 134 LPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPL 193
+ CG+PG G + GS+F GD + + C F L G V+TC ++ W
Sbjct: 523 IEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQ----WSGNK 578
Query: 194 PSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGY 253
PSC +C SGII SP++P EY NN +C W I++E G I L+F DF +E +
Sbjct: 579 PSCVF--SCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQF 636
Query: 254 DFLEVTGTEGSSL----WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQI 309
DFL V S + F+G +P+ + SS + +RL F SD + RGF+ Y
Sbjct: 637 DFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITY------ 690
Query: 310 ELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTC 369
+ G N C DPGIP G+R G F LGSSV F C
Sbjct: 691 --------------------------TTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHC 724
Query: 370 NEGY-DLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNN 428
++G+ QGS+ ITC+ + D WS P C A C HL SG+I P +P Y ++
Sbjct: 725 DDGFVKTQGSESITCI-LQDGNVVWSSTVPRCEA-PCGGHLTASSGVILPPGWPGYYKDS 782
Query: 429 AHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIV 488
HC WII A P IK+ F+ F E YDTL V DG ++ GT P ++
Sbjct: 783 LHCEWIIEA-KPGHSIKITFDRFQTEVNYDTLEVRDG--PASSSPLIGEYHGTQAPQFLI 839
Query: 489 STNHQMWLLFQTDGSGSSLGFKASYEEI--EQGSCGDPGIPAYGRREGSRFHHGDTLKFE 546
ST + M+LLF TD S SS+GF YE + E SC DPGIP G R G F T+ F
Sbjct: 840 STGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFS 899
Query: 547 CQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVW 606
C P + L + + C++N+QW+ P C C SG VLSP +P+ Y N L+C W
Sbjct: 900 CDPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTW 959
Query: 607 LILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITS---SGHV 663
I + + F+ +E D+L+I + + PV +G+ LP +I +
Sbjct: 960 TIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPV-ARLTGSVLPHTIKAGLFGNFT 1018
Query: 664 ARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLG 723
A+L F +D S GFNITF+ + C DPGVP +R G +G S++F C G+
Sbjct: 1019 AQLRFISDFSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGY-R 1077
Query: 724 TQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIE 783
+G+ +TC L G VW++ + RC A CG + GT+LSP +P Y + C + IE
Sbjct: 1078 LEGATKLTC-LGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIE 1136
Query: 784 AQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLI-STSNYLYLLF 842
+ G I + F+ DTL+V DG+ S+ +G + ++ ++ STSN+L+L F
Sbjct: 1137 TEAGKGIHLRTRSFQL-FEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEF 1195
Query: 843 STDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQR-HGNDFYVGALVTFSCDSGYTLSD 901
+T+ S +D GFQL Y + L C DPGIP G R + +V +SC+ GY +
Sbjct: 1196 NTNGSDTDQGFQLTYTSFDLVK--CEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHG 1253
Query: 902 GEPLECEPNFQ--WSRALPSCEALCGGFIQ-GSSGTILSPGFPDFYPNNLNCTWIIETSH 958
L C + W + LPSC A CGG I +SG ILSPG+P Y NNL+CTWIIE
Sbjct: 1254 SNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADP 1313
Query: 959 GKGVFFTFHTFHLESGHDYLLITENGSFTQ-PLRQLTGSRLPAPISAGLYGNFTAQVRFI 1017
GK + F F E HD L + + + L++ +GS LP I + + + T Q F
Sbjct: 1314 GKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHS-TFNSLTLQ--FD 1370
Query: 1018 SDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARI 1077
SDF +S GF+I FS C +P +P R G GDT+TF C PGY+L+G A+I
Sbjct: 1371 SDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKI 1430
Query: 1078 TCLG-GRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGI 1136
TC+ R W P C+A CG ++TG G +LSPN+P Y EC + ++ P I
Sbjct: 1431 TCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVI 1490
Query: 1137 QLKARAFELSEG-DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENT 1195
L ++F + D L +Y+G ++++ L+G + S+ + S+ +SL+L F +DA
Sbjct: 1491 ALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQ-APERIESSGNSLFLAFRSDASVG 1549
Query: 1196 SKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSG 1255
GF + F C DPG G +V + GS++++ CD GY + + C+ G
Sbjct: 1550 LSGFAIEFKEKPREACFDPGNIMNGTRVGTDFKL-GSTITYQCDSGYKILDPSSITCVIG 1608
Query: 1256 E--RRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLH 1313
+ +WD+ LP+C A CGG G G VLSP YP Y C+++I +
Sbjct: 1609 ADGKPSWDQVLPSCNAPCGGQYTGS-EGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQ 1667
Query: 1314 FLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLH-STFNSVVLQFSTDFFTSKQG 1372
F F T ++D+ ++DG LL LSG + L +T N ++L+FS S +G
Sbjct: 1668 FAYFQT-ALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARG 1726
Query: 1373 FAIQFSV---STATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIE 1429
F + ++ T C+ P+ G R G + AG F+C+PGY LQGS + C +
Sbjct: 1727 FHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVP 1786
Query: 1430 NRFF-WQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFN 1488
N W + P+C+ PC G+ T G ILSP YPEPY C WK+ V+ I +
Sbjct: 1787 NALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVI 1846
Query: 1489 IFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVI 1548
F E +D L I+DG D +P +GSF G+ +P + S+SN L+L F+SD SV+ AGF +
Sbjct: 1847 SFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHL 1906
Query: 1549 DYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVW 1608
+Y +C +P N ++G + +++ C GY ++G S +SC+ G + W
Sbjct: 1907 EYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRR--W 1964
Query: 1609 NNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTAL 1668
N P P+C A CGG GV+LSP +P +Y + C + +++P Y QF F T
Sbjct: 1965 NYPSPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEA 2024
Query: 1669 N-DVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAV 1727
N D +E+ +G S ++ SG+ +L L+T+++ LI F + +GF YQA
Sbjct: 2025 NHDFLEIQNGPYHTSPMIGQFSGTDLPAAL-LSTTHETLIHFYSDHSQNRQGFKLAYQAY 2083
Query: 1728 PRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNV 1787
C P + G + SD+SVG V FEC GY L G P + C G WN
Sbjct: 2084 ---ELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTC--QHGINRNWNY 2138
Query: 1788 SAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNW 1847
P C PCG N+T + GTI SPGFP+ Y +C+W I VP G G+ I TE
Sbjct: 2139 PFPRCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN 2198
Query: 1848 DSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLS 1907
D + V+DG D LG FSG T S++NQ+ L F+SD S + F L + L
Sbjct: 2199 DYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS-NGGFFVLNFHAFQLK 2257
Query: 1908 SC-PEPAVPSNGVKT-GERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCI 1965
C P PAVP + T + + + D V +QC PGY L G ++C + ++ P C
Sbjct: 2258 KCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE 2317
Query: 1966 AQCGGTVEE--MEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIE 2023
AQC GVILSPG+PGNY ++ CSW I + + I F +E D +E
Sbjct: 2318 AQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALE 2377
Query: 2024 IRNGPYETSRMMGRFSGSEL-PSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ----DLTY 2078
+ +G S ++ SG+ S+ S S++ + + +DH+ ++ GFK+ Y LT+
Sbjct: 2378 VFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTH 2437
Query: 2079 SHQISSFLR----------------GFDLSELERTNSTPPVAASYVWD-LDPGCEAYELQ 2121
+ L G+ + Y WD L P C+A
Sbjct: 2438 PLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAV--- 2494
Query: 2122 ECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLT--CQH-GTNRNWDHPLPKC 2178
C PE NG G + + V +EC G++L T CQ G N P P C
Sbjct: 2495 SCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKP-PTC 2553
Query: 2179 EVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITI 2238
+ +I + S + L++ G+ + LL+ + +G +
Sbjct: 2554 KPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLE-GWRLLRCQANGTWNIG 2612
Query: 2239 WDGPQ------------QTAPRLGVFTRSMAKKTVQSSSNQVLLKFH-RDAATGGIFAIA 2285
+ P ++G T A ++ L+ H R+ G+++ +
Sbjct: 2613 DERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGS 2672
Query: 2286 FSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFE 2345
+ C P + N + + F+ D V Y+C PGF LVG + C ++
Sbjct: 2673 ETRCLAGHCGSPDPIVNGHI--SGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDH--KWS 2728
Query: 2346 GPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSE 2405
G P+C V ++ +PG+ T + N + Y L
Sbjct: 2729 GQTPVC---------------VPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLL-- 2771
Query: 2406 KQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYN-------RKG 2458
+ + SPL N S P V ++ + Y +KG
Sbjct: 2772 QGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKG 2831
Query: 2459 FKIRYS-------------------APYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGY 2499
F + S A C P P + + G+ T G +H+ C
Sbjct: 2832 FYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTY-GAVVHYSCRGSE 2890
Query: 2500 RLVGHSMAICTRHPQGYHLWSEAIPLCQALS---CGLPEAPKNGMVFGKEYTVGTKAMYS 2556
L+G+ +C WS A+P C + CG P P +G G ++ + +S
Sbjct: 2891 SLIGNDTRVCQEDSH----WSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFS 2946
Query: 2557 CSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQF 2616
C G+ L+ E T CL G WS + P C V+C + + + ++ F
Sbjct: 2947 CEMGHQLRGSPERT--CLLNGSWS--GLQPVCEAVSCGNPGTPT----NGMIVSSDGILF 2998
Query: 2617 QAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVY 2676
+ ++ C GY +G C ANG W+ + P C IISCG+ NG + GT +
Sbjct: 2999 SSSVIYACWEGYKTSGLMTRHCTANGTWT--GTAPDCTIISCGDPGTLANGIQFGTDFTF 3056
Query: 2677 GATAIFSCNSGYTL--VGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGENYSY 2734
T + CN GY + V S C +G W+ S+ C A C P P+ NG + G ++ +
Sbjct: 3057 NKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRW 3116
Query: 2735 RGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGA 2794
S+ Y C G++L ++ C+ W G+ P C+ V CG PG P ++SG S+T +
Sbjct: 3117 GSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKS 3176
Query: 2795 VVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGD-SFDP 2853
V + C LVG+S R+C DG W+G P C + C DPG P GI+ ++
Sbjct: 3177 EVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEV 3236
Query: 2854 GTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFS 2913
G+ + F C G+ ++GS+ RTC AN +WSG Q EC +C P TP++A V D F
Sbjct: 3237 GSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFG 3296
Query: 2914 SSIVYECREGYY-ATGLLSRHCSVNGTWTGSDPEC 2947
++VY C G++ A G R C + WTG P C
Sbjct: 3297 YTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVC 3331
Score = 1395 bits (3610), Expect = 0.0
Identities = 950/3041 (31%), Positives = 1425/3041 (46%), Gaps = 277/3041 (9%)
Query: 401 RARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTL 460
+ + C ++GP+G I SP FP Y N A+C WII ++ I+L+F F LE +D L
Sbjct: 28 KGQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNR-IQLSFHTFALEEDFDIL 86
Query: 461 TVGDG-GQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQG 519
+V DG Q G+ K L+G +P IVST + L F TD + S+ GFKA YE +
Sbjct: 87 SVYDGQPQQGNLKV---RLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSH 143
Query: 520 SCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITC----QKNNQWSAKKPGC- 574
+CG+PG G G+RF+ GD +++ C P + L G +TC W P C
Sbjct: 144 TCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCR 203
Query: 575 -VFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLV 633
+C S + SP++P +Y N+ C W ILA P I L F D +E +DFL
Sbjct: 204 AEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLE 263
Query: 634 IKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNE--- 690
I + EAP + +G LPS + SS + RL F +D + ++GFN F + E
Sbjct: 264 I---SGTEAPSI-WLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKS 319
Query: 691 -----------------------------CPDPGVPVNGKRFG-DSLQLGSSISFLCDEG 720
CPDPG+P NG+R G D ++G+++ F C++
Sbjct: 320 RGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDN 379
Query: 721 FLGTQGSETITCV-LKEGSVVWNSAVLRCEA-PCGGHLTSPSGTILSPGWPGFYKDALSC 778
++ QGS++ITC + E W+ C A CG +L PSG I SP +P Y+D C
Sbjct: 380 YV-LQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHC 438
Query: 779 AWVI-EAQPGYPIKITFDRFKTEVNYDTLEVRD----GRTYSAPLIGVYHGTQVPQFLIS 833
WVI P IK+ F+ F+ E YDTL V D G T S ++ V G+ VP ++S
Sbjct: 439 VWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRS--VLYVLTGSSVPDLIVS 496
Query: 834 TSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSC 893
SN ++L +D S GF+ Y+ I + C DPGIP G+R G+ F G +TF C
Sbjct: 497 MSNQMWLHLQSDDSIGSPGFKAVYQEI--EKGGCGDPGIPAYGKRTGSSFLHGDTLTFEC 554
Query: 894 DSGYTLSDGEPLECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWI 953
+ + L + C+ N QWS PSC C SSG ILSP +P+ Y NN+NC W+
Sbjct: 555 PAAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWL 614
Query: 954 IETSHGKGVFFTFHTFHLESGHDYLLITENG-SFTQPLRQLTGSRLPAPISAGLYGNFTA 1012
I + G + F+ F +E D+L + ++G S L +G+ +P+ +++
Sbjct: 615 IISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLAS---SGHIV 671
Query: 1013 QVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGY-RL 1071
++ F SD S + GFNIT++ + C +P +P R G +F +G +++F C G+ +
Sbjct: 672 RLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKT 731
Query: 1072 EGTARITC-LGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQT 1130
+G+ ITC L +WSS +PRC A CG +T + G +L P +P Y ++ C + I+
Sbjct: 732 QGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEA 791
Query: 1131 QPGKGIQLKARAFELSEG-DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFI 1189
+PG I++ F+ D L+V DG +S+ L+G + H L ST + ++L F
Sbjct: 792 KPGHSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEY-HGTQAPQFLISTGNFMYLLFT 850
Query: 1190 TDAENTSKGFELHFSS--FELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGS 1247
TD +S GF +H+ S E C DPG P G++ H S+V+FSCDPGY+L
Sbjct: 851 TDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHR-HGGDFGIRSTVTFSCDPGYTLSDD 909
Query: 1248 EELLCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAG 1307
E L+C W+ LP+C A CGG ++G+ SG VLSPG+P Y ++LNC WTIE G
Sbjct: 910 EPLVC--ERNHQWNHALPSCDALCGGYIQGK-SGTVLSPGFPDFYPNSLNCTWTIEVSHG 966
Query: 1308 CTIGLHFLVFDTEEVHDVLRIW-DGPVESGVLLKELSGPALPKDLHSTF---NSVVLQFS 1363
+ + F F E HD L I DG V L+G LP + + + L+F
Sbjct: 967 KGVQMIFHTFHLESSHDYLLITEDGSFSEPV--ARLTGSVLPHTIKAGLFGNFTAQLRFI 1024
Query: 1364 TDFFTSKQGFAIQFSVSTATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEI 1423
+DF S +GF I FS C+DPG+P R G + GDS F C GY L+G+ ++
Sbjct: 1025 SDFSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKL 1084
Query: 1424 SCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVI 1483
+C+ R W P C+A CG + G G +LSPN+P Y EC +K+ I
Sbjct: 1085 TCLG-GGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGI 1143
Query: 1484 ALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRI-ESSSNSLFLAFRSDASVS 1542
L F L G D L +YDG+DS S +G+F ++L G I S+SN L+L F ++ S +
Sbjct: 1144 HLRTRSFQLFEG-DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDT 1202
Query: 1543 NAGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYY-CHGGYEVEGTSTLSCILG 1601
+ GF + YT C DPG G R+ + +V Y C+ GY + G++TL+C+ G
Sbjct: 1203 DQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSG 1262
Query: 1602 PDGKPVWNNPRPVCTAPCGGQ-YVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQ 1660
+ VW+ P P C A CGGQ + + G +LSP YP Y + C + + +
Sbjct: 1263 --DRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLH 1320
Query: 1661 FAFFHTAL-NDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARG 1719
F F T + +D+++V DG LL SGS E + +T N + ++F + G
Sbjct: 1321 FIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIH-STFNSLTLQFDSDFFISKSG 1379
Query: 1720 FHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVP 1779
F + + A C+ P+ G R G G V F+C+ GY LQG +I C+ +
Sbjct: 1380 FSIQFST---SIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLN 1436
Query: 1780 GALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVV 1839
W PTC+ CGGNLT G ILSP +P+PY C W++ V I +
Sbjct: 1437 NRFF-WQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFK 1495
Query: 1840 SFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHL 1899
SF E ++D L +++G D+ ++GS+ G+ P + S+ N L+L F SD SV +GF +
Sbjct: 1496 SFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAI 1555
Query: 1900 EYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRR--W 1957
E+K +C +P NG + G + + +++QC+ GY + + I+C+ G + W
Sbjct: 1556 EFKEKPREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSW 1615
Query: 1958 NYPPPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEP 2017
+ P C A CGG EGV+LSP +P NY + C + I +P F QF F T
Sbjct: 1616 DQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTAL 1675
Query: 2018 NHDYIEIRNGPYETSRMMGRFSGSELPSSL-LSTSHETTVYFHSDHSQNRPGFKLEYQDL 2076
N D E+ +G + +R++ SGS +L L+TS++ + F + + GF YQ
Sbjct: 1676 N-DLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQ-- 1732
Query: 2077 TYSHQISSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRG 2136
+ RT+ T + P+P G G
Sbjct: 1733 ----------------AVPRTSDT------------------QCSSVPEPR---YGRRIG 1755
Query: 2137 AGYNVGQSVTFECLPGYQLTGHPVLTCQHGTN--RNWDHPLPKCEVPCGGNITSSNGTVY 2194
+ ++ G V FEC PGY L G L CQ N W+ +P C VPC GN T GT+
Sbjct: 1756 SEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTIL 1815
Query: 2195 SPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTR 2254
SPG+P PY ++ +C+W I V G G+++ + TE + D + I DG TAPRLG F+
Sbjct: 1816 SPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSG 1875
Query: 2255 SMAKKTVQSSSNQVLLKFHRD---AATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEE 2311
+ + S+SNQ+ L F D AA G F + + L C P + N+ + +
Sbjct: 1876 TTVPALLNSTSNQLYLHFQSDISVAAAG--FHLEYKTVGLAACQEPALPSNS--IKIGDR 1931
Query: 2312 FNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQ 2371
+ + D++ ++C PG+TL G ++C GT ++ P P+C C L+ GVILS
Sbjct: 1932 YMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATC--GGTLSTLGGVILSP 1989
Query: 2372 SYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNY 2431
+PGSYP C+W + + Y + F +E +D EI +GP SP++ SG
Sbjct: 1990 GFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGT- 2048
Query: 2432 SAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA---PYCSLPRAPLHGFILGQTSTQPG 2488
P + S+++ + + SDH+ NR+GFK+ Y A C P +G+++ + G
Sbjct: 2049 DLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQNGYMI-NSDYSVG 2107
Query: 2489 GSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGKEYT 2548
S+ F C GY L+GH + C +H + W+ P C A CG +NG ++ +
Sbjct: 2108 QSVSFECYPGYILIGHPVLTC-QHGINRN-WNYPFPRCDA-PCGYNVTSQNGTIYSPGFP 2164
Query: 2549 VGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRL 2608
+ C L ++ L V PD +S +
Sbjct: 2165 DEYPILKDC---IWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQNSPQLGVFSGNT 2221
Query: 2609 IFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGH 2668
ET Y Q++L + G V+ A ++ C P P
Sbjct: 2222 ALETAYSSTNQVLLKFHSDFSNGGFFVLNFHA------------FQLKKCQPPPAVPQAE 2269
Query: 2669 RIGTLSVY--GATAIFSCNSGYTLVGSRVRECMAN------GLWSGSEVRCLAGHCGTPE 2720
+ + G + C+ GYTLVG+ + C + G E +C A T
Sbjct: 2270 MLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVRTGS 2329
Query: 2721 PIV-------NGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHW---------SG 2764
V + N + S+ V N I + V Q + + SG
Sbjct: 2330 SGVILSPGYPGNYFNSQTCSWSIKVEPNYN-----ITIFVDTFQSEKQFDALEVFDGSSG 2384
Query: 2765 KTPFCVLVSCGHPGSPPHSQMSGDSY---------------------------------- 2790
++P V++S H + S Y
Sbjct: 2385 QSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTHPLKNGGI 2444
Query: 2791 ------TVGAVVRYSCIGKRTLVGNSTRMCGLDG----HWTGSLPHCSGTSVGVCGDPGI 2840
VG+ V Y C +VG+S C + W P C S CG P
Sbjct: 2445 LNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVS---CGIPES 2501
Query: 2841 PAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERT--CQANGSWS--GSQPECGVISCGNP 2896
P +G G+ F + + + C G L S + T CQ +G WS G P C ++C +
Sbjct: 2502 PGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSI 2561
Query: 2897 GTPSNARVVF---SDGL-VFSSSIVYECREGYYATGLLSRHCSVNGTWTGSD--PECLVI 2950
+ V++ S L + + ++ C GYY G C NGTW D P C VI
Sbjct: 2562 EAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVI 2621
Query: 2951 NCGDPGIPANGLRLGNDFRYNKTVTYQCVPGY-MMESHRVSVLSCTKDRTWNGTKPVCKA 3009
+CG P NG ++G Y T + C GY ++ SH V C + W+G++ C A
Sbjct: 2622 SCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSH---VRECLANGLWSGSETRCLA 2678
Query: 3010 LMCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVF 3069
C P I NG + G F + +V Y C G++L +V C + W+G+ P C P+
Sbjct: 2679 GHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPIT 2738
Query: 3070 CGDPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLT 3129
CG PG P+ G F+ V+F+C+ +L G R C+S+G WS P+C +
Sbjct: 2739 CGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC---RVV 2795
Query: 3130 TCADPGVPQ----FGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDC 3185
C+DPG + G QN + ++ G ++L+ C+KG+ L GS+ TC+ N W + P C
Sbjct: 2796 NCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKC 2855
Query: 3186 VPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPIC 3245
+ C P P +A V +L + G + YSC+ SL G++ R C+ D W+G P C
Sbjct: 2856 LAISCGHPGVPANA-VLTGELFTYGAVVHYSCRGSESLI-GNDTRVCQEDSHWSGALPHC 2913
Query: 3246 LEVRPS--GRPINTAREPPLTQALIPGDVFAKNSLWKGAYE 3284
P G P A L GD F SL + + E
Sbjct: 2914 TGNNPGFCGDPGTPAHGSRL------GDDFKTKSLLRFSCE 2948
Score = 1057 bits (2733), Expect = 0.0
Identities = 503/1007 (49%), Positives = 653/1007 (64%), Gaps = 30/1007 (2%)
Query: 2488 GGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWS--EAIPLCQALSCGLPEAPKNGMVFGK 2545
G + C+ GY L G + C Q W+ + P C+ +SCG P NG G
Sbjct: 2582 GAQVLLSCSPGYYLEGWRLLRC----QANGTWNIGDERPSCRVISCGSLSFPPNGNKIGT 2637
Query: 2546 EYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGR 2605
G A+++C+ GY L ECL GLWS +C+ C I H
Sbjct: 2638 LTVYGATAIFTCNTGYTLVGSH--VRECLANGLWSGSET--RCLAGHCGSPDPIVNGH-- 2691
Query: 2606 WRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPP 2665
I + ++ ++ C+PG+ G V C + KWS TP C I+CG P
Sbjct: 2692 ---ISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWS--GQTPVCVPITCGHPGNPA 2746
Query: 2666 NGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNG 2725
+G G+ F+CN+GY L G +C +NG WS C +C P + N
Sbjct: 2747 HGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENA 2806
Query: 2726 HING-----ENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSP 2780
+G E++ Y S++Y C GF L+G S C + W P C+ +SCGHPG P
Sbjct: 2807 IRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVP 2866
Query: 2781 PHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGI 2840
++ ++G+ +T GAVV YSC G +L+GN TR+C D HW+G+LPHC+G + G CGDPG
Sbjct: 2867 ANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGT 2926
Query: 2841 PAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPS 2900
PAHG RLGD F +++RFSCE GH LRGS ERTC NGSWSG QP C +SCGNPGTP+
Sbjct: 2927 PAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPT 2986
Query: 2901 NARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPAN 2960
N +V SDG++FSSS++Y C EGY +GL++RHC+ NGTWTG+ P+C +I+CGDPG AN
Sbjct: 2987 NGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLAN 3046
Query: 2961 GLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPN 3020
G++ G DF +NKTV+YQC PGY+ME+ + + CTKD WN +KPVCKA++C PP + N
Sbjct: 3047 GIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQN 3106
Query: 3021 GKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGR 3080
G V GSDF WGSS++Y+C++GYQLS A+ +CEG G W GE+PQC PVFCGDPG+P+ GR
Sbjct: 3107 GTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGR 3166
Query: 3081 REDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFG 3140
+ F+Y+S V F C P +LVGS RR CQ+DGTWSG QP+CIDP TC DPG P FG
Sbjct: 3167 LSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFG 3226
Query: 3141 IQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHAN 3200
IQN+S+GY+VGSTV FRC+KGY +QGSTTRTCL NLTWSG +C+PH CRQPETP HA+
Sbjct: 3227 IQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHAD 3286
Query: 3201 VGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRPINTARE 3260
V A+DLP+ GYTL+Y+C GF L GGSEHRTCKAD WTGK P+C + + E
Sbjct: 3287 VRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVC-----KSKGVREVNE 3341
Query: 3261 PPLTQALIPGDVFAKNSLWKGAYEYQGKKQPAMLRVTGFQVANSKVNATMIDHSGVELHL 3320
+T+ +P DVF NSLWKG YEY GK+QPA L V F +SKVNAT + S VEL L
Sbjct: 3342 -TVTKTPVPSDVFFVNSLWKGYYEYLGKRQPATLTVDWFNATSSKVNATFSEASPVELKL 3400
Query: 3321 AGTYKKEDFHLLLQVYQITGPVEIFMNKFKDDHWALDGHVSSESSGATFIYQGSVKGQGF 3380
G YKKE+ HLLL+ +QI G +IF++KF++D+W LDG+VSS F +QG + G+ F
Sbjct: 3401 TGIYKKEEAHLLLKAFQIKGQADIFVSKFENDNWGLDGYVSSGLERGGFTFQGDIHGKDF 3460
Query: 3381 GQFGFQRLDLRLLESDPESIGRHFASNSSSVAAAILVPFIALIIAGFVLYLYKHRRRPKV 3440
G+F +R D L D +S + ++S SVAAAILVPF ALI++GF YLYKHR RPKV
Sbjct: 3461 GKFKLERQD--PLNPDQDSSSHYHGTSSGSVAAAILVPFFALILSGFAFYLYKHRTRPKV 3518
Query: 3441 PFNGYAGHENTNVRATFENPMYDRNIQPTDIMASEAEFTVSTVCTAV 3487
+NGYAGHEN+N +A+FENPMYD N++PT+ A + T++TVCT V
Sbjct: 3519 QYNGYAGHENSNGQASFENPMYDTNLKPTEAKAVRFDTTLNTVCTVV 3565
Score = 966 bits (2496), Expect = 0.0
Identities = 740/2443 (30%), Positives = 1094/2443 (44%), Gaps = 227/2443 (9%)
Query: 16 SHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEE 75
+H S C + G +GTV SPGFP YPN NCTWTI +Q++F +F LE
Sbjct: 921 NHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLES 980
Query: 76 DFDVLSVFDGPPQPENLRTRLTGFQLPATIVSAA---TTLSLRLISDYAVSAQGFHATYE 132
D L + + E + RLTG LP TI + T LR ISD+++S +GF+ T+
Sbjct: 981 SHDYLLITEDGSFSEPV-ARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFS 1039
Query: 133 VLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFP 192
C +PG + G F +GD + +SC LG+ LEG LTC G W P
Sbjct: 1040 EYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRR--VWSAP 1097
Query: 193 LPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG 252
LP C A+ CG +++G G + SP+FPS Y NN +C + I E G I L FQL +G
Sbjct: 1098 LPRCVAE--CGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEG 1155
Query: 253 YDFLEVTGTEGSSL---WFTGASLPAPVI-SSKNWLRLHFTSDGNHRQRGFSAQYQVKKQ 308
G + SS FT L ++ S+ N L L F ++G+ +GF Y
Sbjct: 1156 DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDL 1215
Query: 309 IELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSS-VQF 367
++ C DPGIP G R+ + + V +
Sbjct: 1216 VK--------------------------------CEDPGIPNYGYRIRDEGHFTDTVVLY 1243
Query: 368 TCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDN 427
+CN GY + GS +TC+ S W P C A SG I SP +P YDN
Sbjct: 1244 SCNPGYAMHGSNTLTCL--SGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDN 1301
Query: 428 NAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLI 487
N HC WII A +P K I L F FD E +D L V DG D D +L +G+++P+ I
Sbjct: 1302 NLHCTWIIEA-DPGKTISLHFIVFDTEMAHDILKVWDGPVDSD--ILLKEWSGSALPEDI 1358
Query: 488 VSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFEC 547
ST + + L F +D S GF + +C DPG+P G R G GDT+ F+C
Sbjct: 1359 HSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSREAGDTVTFQC 1418
Query: 548 QPAFELVGQKAITC-QKNNQ--WSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHC 604
P ++L GQ ITC Q NN+ W P C+ +C N T P+GV+LSPNYP+ Y C
Sbjct: 1419 DPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKEC 1478
Query: 605 VWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVA 664
W + P+ I L F ++EP +DFL I +G + +P++G++ G+Q P I SSG+
Sbjct: 1479 DWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSL 1538
Query: 665 RLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGT 724
L F++D S G GF I F C DPG +NG R G +LGS+I++ CD G+
Sbjct: 1539 FLAFRSDASVGLSGFAIEFKEKPREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKIL 1598
Query: 725 QGSETITCVL-KEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIE 783
S +ITCV+ +G W+ + C APCGG T G +LSP +P Y C + I
Sbjct: 1599 DPS-SITCVIGADGKPSWDQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSIT 1657
Query: 784 AQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFL-ISTSNYLYLLF 842
+ + F F+T +N D E+ DG A L+ G+ + L ++TSN + L F
Sbjct: 1658 VPKEFVVFGQFAYFQTALN-DLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRF 1716
Query: 843 STDKSHSDIGFQLRYETITLQSD-HCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSD 901
S S GF Y+ + SD C P G+R G++F G++V F C+ GY L
Sbjct: 1717 SAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQG 1776
Query: 902 GEPLECE--PN--FQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETS 957
L C+ PN QW+ +PSC C G GTILSPG+P+ Y NNLNC W I +
Sbjct: 1777 STALHCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVT 1836
Query: 958 HGKGVFFTFHTFHLESGHDYLLITENGSFTQP-LRQLTGSRLPAPISAGLYGNFTAQVRF 1016
G G+ +F E D L I + G T P L +G+ +PA +++ + + F
Sbjct: 1837 EGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNS---TSNQLYLHF 1893
Query: 1017 ISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTAR 1076
SD S++ GF++ + L C+EP +P+ SI+ G ++ V D L+F C PGY L+G +
Sbjct: 1894 QSDISVAAAGFHLEYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSH 1953
Query: 1077 ITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGI 1136
I+C+ G R W+ P P C+A CG +++ G +LSP FP +Y NN +C + I G G
Sbjct: 1954 ISCMPGTVRRWNYPSPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGA 2013
Query: 1137 QLKARAFEL-SEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENT 1195
++ F + D L++ +G +++ ++G FS +++ L++T +L + F +D
Sbjct: 2014 HIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETL-IHFYSDHSQN 2072
Query: 1196 SKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSG 1255
+GF+L + ++EL C DP + GY ++ + + G SVSF C PGY L G L C G
Sbjct: 2073 RQGFKLAYQAYELQNCPDPPPFQNGYMINSD-YSVGQSVSFECYPGYILIGHPVLTCQHG 2131
Query: 1256 ERRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFL 1315
R W+ P P C A CG V + +G + SPG+P Y +CIW I G + ++F
Sbjct: 2132 INRNWNYPFPRCDAPCGYNVTSQ-NGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFT 2190
Query: 1316 VFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAI 1375
+ TE V+D + +WDGP ++ L SG + +S+ N V+L+F +D F++ F +
Sbjct: 2191 LLQTEAVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD-FSNGGFFVL 2249
Query: 1376 QFSVSTATSCN-DPGIPQ-NGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFF 1433
F C P +PQ D +E GD +QC PGY L G+ ++C K+ ++
Sbjct: 2250 NFHAFQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTC-KLSSQLQ 2308
Query: 1434 WQPSPPTCIAPCGGD--LTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFN 1491
++ S PTC A C + TG SGVILSP YP Y + C W + V P+Y I + + F
Sbjct: 2309 FEGSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQ 2368
Query: 1492 LEPGYDFLHIYDGRDSLSPLIGSFYGSQL-PGRIESSSNSLFLAFRSDASVSNAGFVIDY 1550
E +D L ++DG SPL+ G+ S SN L+L + +D + S GF I Y
Sbjct: 2369 SEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRY 2428
Query: 1551 TENPRESCFDPGSIKNGTRVGSDL-KLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWN 1609
P S P +KNG + +GS V Y+C GY + G S +C P G W+
Sbjct: 2429 AA-PYCSLTHP--LKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWD 2485
Query: 1610 NPRPVCTA--------PCGGQYVGSD-----GVVLSPNYPQNYTSGQICLYFVTVPKDYV 1656
+ P+C A P G + G++ VV + S Q +
Sbjct: 2486 SLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWS 2545
Query: 1657 VFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAP 1716
G+ +E RL+S S + G + L+ S ++
Sbjct: 2546 NKGKPPTCKPVACPSIEAQLSEHVIWRLVSG-SLNEYGAQVLLSCSPGYYLEGWRLLRCQ 2604
Query: 1717 ARGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECL 1776
A G + P C S+ P G ++G+ GA F CN+GY L GS ECL
Sbjct: 2605 ANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECL 2664
Query: 1777 PVPGALAQWNVSAPTCVV-PCGGNLTERRGTILSPGFP--EPYLNSLNCVWKIVVPEGAG 1833
A W+ S C+ CG G I GF + + N +++V G
Sbjct: 2665 ----ANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLV---GTS 2717
Query: 1834 IQIQVVSFVTEQNWDS-----LEVFDG-ADNTVTMLGSFSGTTVPALLNSTSNQLY-LHF 1886
++I + + W + + G N + S + ++N T N Y L
Sbjct: 2718 VRI----CLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQG 2773
Query: 1887 YSDISVSAAG-FHLEYKTVGLSSCPEPAVPSNGVKTG-----ERYLVNDVVSFQCEPGYA 1940
S + G + T + +C +P N ++ G E + + + C+ G+
Sbjct: 2774 VSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFY 2833
Query: 1941 LQGHAHISCMPGTVRRWNYPPPLCIA-QCGGTVEEMEGVILSPGFPGNYPSNMDC----- 1994
L G + ++CM + W+ P C+A CG V+ F + C
Sbjct: 2834 LLGSSALTCMANGL--WDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSES 2891
Query: 1995 -------------SWKIALP------------VGFGAH----------IQFLNFSTEPNH 2019
W ALP G AH L FS E H
Sbjct: 2892 LIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGH 2951
Query: 2020 DYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYS 2079
++R P T + G +SG + +S + T G + + +S
Sbjct: 2952 ---QLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGT---------PTNGMIVSSDGILFS 2999
Query: 2080 HQ-ISSFLRGFDLSELERTNSTPPVAASYVW-DLDPGCEAYELQECPDPEPFANGIVRGA 2137
I + G+ S L + T A+ W P C + C DP ANGI G
Sbjct: 3000 SSVIYACWEGYKTSGLMTRHCT----ANGTWTGTAPDC---TIISCGDPGTLANGIQFGT 3052
Query: 2138 GYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCE-VPCGGNITSSNGTVYSP 2196
+ ++V+++C PGY + T + + W+ P C+ V C NGTV
Sbjct: 3053 DFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGS 3112
Query: 2197 GFPSPYSSSQDCVWLITVPIGHGVRLNLS-LLQTEPSGDFITIWDG--PQQTAPRLG--- 2250
F S S C+ G +L+ S +L E G +W G PQ G
Sbjct: 3113 DFRWGSSISYSCM--------DGYQLSHSAILSCEGRG----VWKGEIPQCLPVFCGDPG 3160
Query: 2251 -----------------VFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTK 2293
VF + + + SS +V D GI T
Sbjct: 3161 IPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVC---QADGTWSGIQPTCIDPAHNT- 3216
Query: 2294 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTC 2336
CP P P+ + + + +G V +RC G+ + G+ TC
Sbjct: 3217 CPDPG-TPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTC 3258
Score = 289 bits (739), Expect = 4e-77
Identities = 362/1508 (24%), Positives = 546/1508 (36%), Gaps = 287/1508 (19%)
Query: 4 ISIAPGP--RWQVQSHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQ 61
IS PG RW S P C L G + SPGFP YPN +CTW I+
Sbjct: 1954 ISCMPGTVRRWNYPS--PLCIA-TCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIG 2010
Query: 62 HRIQLVFQSFALEEDFDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYA 121
+ + F +F+ E + D L + +GP + + +G LPA ++S + SD++
Sbjct: 2011 YGAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHS 2070
Query: 122 VSAQGFHATYEVLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHA 181
+ QGF Y+ C +P NG S +++G V + C G+ L GH VLTC
Sbjct: 2071 QNRQGFKLAYQAYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQH 2130
Query: 182 GSENSATWDFPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIA 241
G + W++P P C D CG + Q+G I SP FP EY DC W I G +
Sbjct: 2131 GINRN--WNYPFPRC--DAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVY 2186
Query: 242 LVFIDFQLEDGYDFLEV-TGTEGSSLW---FTGASLPAPVISSKNWLRLHFTSD---GNH 294
+ F Q E D++ V G + +S F+G + SS N + L F SD G
Sbjct: 2187 INFTLLQTEAVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGF 2246
Query: 295 RQRGFSAQYQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKR 354
F A +Q+KK P P +P+
Sbjct: 2247 FVLNFHA-FQLKK----------------------------------CQPPPAVPQAEML 2271
Query: 355 L-GSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLR-GP 412
DF +G V++ C+ GY L G+ +TC S + + P C A+ +R G
Sbjct: 2272 TEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQL--QFEGSLPTCEAQCPANEVRTGS 2329
Query: 413 SGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQK 472
SG+I SP +P Y N+ C W I + P+ I + + F E+ +D L V DG Q
Sbjct: 2330 SGVILSPGYPGNYFNSQTCSWSI-KVEPNYNITIFVDTFQSEKQFDALEVFDG--SSGQS 2386
Query: 473 TVLYILTGTSVPDL-IVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGR 531
+L +L+G S ++Q++L + TD + S GFK Y S P + G
Sbjct: 2387 PLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRY-AAPYCSLTHP-LKNGGI 2444
Query: 532 REGSRFHHGDTLKFECQPAFELVGQKAITCQKN----NQWSAKKPGC-VFSCFFNFTSPS 586
+ G + + C+P + +VG TC++N QW + P C SC + +
Sbjct: 2445 LNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGN 2504
Query: 587 GVVLSPNYPEDYGNHLHC--------------------VWLILARPESRIHLAFNDIDVE 626
G + D C +W +P + +A I+ +
Sbjct: 2505 GSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQ 2564
Query: 627 -PQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTT 685
+ + G+ E G Q+ S + ++ + G +
Sbjct: 2565 LSEHVIWRLVSGSLNE-------YGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPS 2617
Query: 686 FRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAV 745
R C P NG + G G++ F C+ G+ GS C+ + +W+ +
Sbjct: 2618 CRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYT-LVGSHVRECL---ANGLWSGSE 2673
Query: 746 LRCEAPCGGHLTSP----SGTILSPGWPGFYKDALSCAWVIEAQPGY-----PIKITFDR 796
RC A GH SP +G I G+ Y+D + V + PG+ ++I
Sbjct: 2674 TRCLA---GHCGSPDPIVNGHISGDGFS--YRDTV----VYQCNPGFRLVGTSVRICLQD 2724
Query: 797 FKTEVNYDTLEVRDGRTYSAPLIGVYHGTQ--VPQFLISTSNYLYLLFSTDKSHSDIGFQ 854
K P G +G++ + + T N YLL ++ Q
Sbjct: 2725 HKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQ 2784
Query: 855 LRYETITLQSDHCLDPGIPVNGQRHG-----NDFYVGALVTFSCDSGYTLSDGEPLECEP 909
T + +C DPG N RHG F G + + C G+ L L C
Sbjct: 2785 WSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMA 2844
Query: 910 NFQWSRALPSCEAL-CGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHT 968
N W R+LP C A+ CG PG P N T + T +G V ++
Sbjct: 2845 NGLWDRSLPKCLAISCG-----------HPG----VPANAVLTGELFT-YGAVVHYSCRG 2888
Query: 969 FHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFN 1028
G+D + E+ ++ L TG+ GF
Sbjct: 2889 SESLIGNDTRVCQEDSHWSGALPHCTGNN---------------------------PGF- 2920
Query: 1029 ITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWS 1088
C +P PA+ R G F L FSC G++L G+ TCL WS
Sbjct: 2921 ----------CGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCL--LNGSWS 2968
Query: 1089 SPLPRCVA-ECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSE 1147
P C A CGN T T G ++S + S
Sbjct: 2969 GLQPVCEAVSCGNPGTPTNGMIVSSD----------------------------GILFSS 3000
Query: 1148 GDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFE 1207
+ ++G S + T + T++ W D
Sbjct: 3001 SVIYACWEGYKTSGLM------------TRHCTANGTWTGTAPDC--------------T 3034
Query: 1208 LIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRG--SEELLCLSGERRTWDRPLP 1265
+I C DPGT G + + F +VS+ C+PGY + S + C R W+ P
Sbjct: 3035 IISCGDPGTLANGIQFGTDFTF-NKTVSYQCNPGYVMEAVTSATIRCTKDGR--WNPSKP 3091
Query: 1266 TCVAECGGTVRGEVSGQVLSPGYPAPYEHNL----NCIWTIEAEAGCTIGL---HFLVFD 1318
C A VL P P P ++ + W C G H +
Sbjct: 3092 VCKA-------------VLCP-QPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILS 3137
Query: 1319 TEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFS 1378
E +W G + L P +P + + S + S FF K F + S
Sbjct: 3138 CEG----RGVWKGEIPQ-CLPVFCGDPGIPAEGRLSGKSFTYK-SEVFFQCKSPFILVGS 3191
Query: 1379 VSTA-------------------TSCNDPGIPQNG-SRSGDSWEAGDSTVFQCDPGYALQ 1418
+C DPG P G S +E G + F+C GY +Q
Sbjct: 3192 SRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQ 3251
Query: 1419 GSAEISCV 1426
GS +C+
Sbjct: 3252 GSTTRTCL 3259
Score = 164 bits (415), Expect = 1e-39
Identities = 284/1178 (24%), Positives = 404/1178 (34%), Gaps = 263/1178 (22%)
Query: 32 GPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDGPPQPEN 91
G +G + SPG+P Y N C+W+I E + I + +F E+ FD L VFDG
Sbjct: 2328 GSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSP 2387
Query: 92 LRTRLTGFQLP-ATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRLPNG-I 149
L L+G + S + L LR +D+A S +GF Y + C L NG I
Sbjct: 2388 LLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYA---APYCSLTHPLKNGGI 2444
Query: 150 QQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQ 209
+ +G KV Y C G+ + GH+ TC WD P C+A
Sbjct: 2445 LNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSC-------- 2496
Query: 210 SGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSSLWFT 269
GI SP S N ++ E + F+LE V +G LW
Sbjct: 2497 -GIPESPGNGSFTGNEFTLDSKVVYECHE-------GFKLESSQQATAVCQEDG--LWSN 2546
Query: 270 GASLPA--PVI--SSKNWLRLHFT---SDGNHRQRGFSAQYQVKKQIELKSRGVKLMPSK 322
P PV S + L H G+ + G AQ + G +L+ +
Sbjct: 2547 KGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYG--AQVLLSCSPGYYLEGWRLLRCQ 2604
Query: 323 DNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRIT 382
N T + S C P G ++G+ G++ FTCN GY L GS
Sbjct: 2605 ANG--TWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRE 2662
Query: 383 CMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSK 442
C+ WS C A H P I+ N I D ++ ++ NP
Sbjct: 2663 CLANG----LWSGSETRCLA----GHCGSPDPIV---NGHISGDGFSYRDTVVYQCNPG- 2710
Query: 443 VIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDG 502
+ L GTSV + W
Sbjct: 2711 ---------------------------------FRLVGTSVR---ICLQDHKW------- 2727
Query: 503 SGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQ 562
SG + +CG PG PA+G GS F+ D + F C + L G C+
Sbjct: 2728 SGQT-------PVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCR 2780
Query: 563 KNNQWSAKKPGC-VFSCFFNFTSPSGVVLSP------NYPE--DYGNHL--HCVWLILAR 611
N QWS+ P C V +C S G V + N+PE +YG + HC
Sbjct: 2781 SNGQWSSPLPTCRVVNC-----SDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLL 2835
Query: 612 PESRIHLAFNDIDVEPQFDFLVIKDG---------ATAEAPVLGTFSGNQLPSSITSSGH 662
S + N + L I G T E G S + G+
Sbjct: 2836 GSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGN 2895
Query: 663 VARLEFQTDHSTGK----RGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCD 718
R+ + H +G G N F C DPG P +G R GD + S + F C+
Sbjct: 2896 DTRVCQEDSHWSGALPHCTGNNPGF-------CGDPGTPAHGSRLGDDFKTKSLLRFSCE 2948
Query: 719 EGFLGTQGSETITCVLKEGSVVWNSAVLRCEA--------PCGGHLTSPSGTILSPG--- 767
G +GS TC+L GS W+ CEA P G + S G + S
Sbjct: 2949 MGHQ-LRGSPERTCLLN-GS--WSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIY 3004
Query: 768 --WPGFYKDAL----------------SCAWVIEAQPG-------YPIKITFDR---FKT 799
W G+ L C + PG + TF++ ++
Sbjct: 3005 ACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQC 3064
Query: 800 EVNYDTLEV--------RDGR-TYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSD 850
Y V +DGR S P+ Q P T + + S+S
Sbjct: 3065 NPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSC 3124
Query: 851 I-GFQLRYETITLQSDH--------------CLDPGIPVNGQRHGNDFYVGALVTFSCDS 895
+ G+QL + I C DPGIP G+ G F + V F C S
Sbjct: 3125 MDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKS 3184
Query: 896 GYTLSDGEPLECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIE 955
+ L C+ + WS P+C I + T PG P F N + + +
Sbjct: 3185 PFILVGSSRRVCQADGTWSGIQPTC-------IDPAHNTCPDPGTPHFGIQNSSRGYEV- 3236
Query: 956 TSHGKGVFFTFHT-FHLESGHDYLLITENGSFTQP-LRQLTGSRLPAPISAGLYGNFTAQ 1013
G VFF +H++ GS T+ L LT S +
Sbjct: 3237 ---GSTVFFRCRKGYHIQ-----------GSTTRTCLANLTWSGIQ-------------- 3268
Query: 1014 VRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGV-GDTLTFSCFPGYRLE 1072
+E C +PE PA++ + + G TL ++C PG+ L
Sbjct: 3269 ------------------TECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLA 3310
Query: 1073 -GTARITCLGGRRRLWSSPLPRC----VAECGNSVTGT 1105
G+ TC + W+ P C V E +VT T
Sbjct: 3311 GGSEHRTCKADMK--WTGKSPVCKSKGVREVNETVTKT 3346
Score = 112 bits (281), Expect = 5e-24
Identities = 136/585 (23%), Positives = 202/585 (34%), Gaps = 102/585 (17%)
Query: 2 RLISIAPGPRWQVQSHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQ 61
RL+ W + P +C PNG YG C T
Sbjct: 2599 RLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGS 2658
Query: 62 HRIQLVFQSFALEEDFDVLSVFDGPPQP-ENLRTRLTGFQLPATIVSAATT------LSL 114
H + + + L+ G P P N GF T+V S+
Sbjct: 2659 HVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSV 2718
Query: 115 RL-ISDYAVSAQGFHATYEVLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEG 173
R+ + D+ S Q V TCG+PG +G GS FNL D V ++CN G+ L+G
Sbjct: 2719 RICLQDHKWSGQT-----PVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQG 2773
Query: 174 HAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTIL 233
+ C + + W PLP+CR + S P F + +
Sbjct: 2774 VSRAQCRSNGQ----WSSPLPTCRVVNC------------SDPGFVENAIRHGQQNFPES 2817
Query: 234 AELGDTIALVFIDFQLEDGYDFLEVTGTE--GSSLWFTGASLPAPVISSKNWLRLHFTSD 291
E G +I + + G+ L + + LW + + +
Sbjct: 2818 FEYGMSIL-----YHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLT 2872
Query: 292 GNHRQRGFSAQYQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPER 351
G G Y + L ++ +++S + L C DPG P
Sbjct: 2873 GELFTYGAVVHYSCRGSESLIGNDTRV--CQEDSHWSGALPHC-TGNNPGFCGDPGTPAH 2929
Query: 352 GKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRG 411
G RLG DF+ S ++F+C G+ L+GS TC+ + +WS +PVC A C
Sbjct: 2930 GSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCL----LNGSWSGLQPVCEAVSCGNPGTP 2985
Query: 412 PSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQ 471
+G+I S + L S VI +E GY T G
Sbjct: 2986 TNGMIVSSD---------------GILFSSSVIYACWE------GYKT-----SGLMTRH 3019
Query: 472 KTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGR 531
T TGT+ PD + SCGDPG A G
Sbjct: 3020 CTANGTWTGTA-PDCTII------------------------------SCGDPGTLANGI 3048
Query: 532 REGSRFHHGDTLKFECQPAF--ELVGQKAITCQKNNQWSAKKPGC 574
+ G+ F T+ ++C P + E V I C K+ +W+ KP C
Sbjct: 3049 QFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVC 3093
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 3696 bits (9584), Expect = 0.0
Identities = 1701/2975 (57%), Positives = 2167/2975 (72%), Gaps = 80/2975 (2%)
Query: 303 YQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLG 362
++VKK I+ KSRG KL P KDNS K S+L + G+ N+CPDPG PE GKR+GSDF LG
Sbjct: 406 HRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLG 465
Query: 363 SSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFP 422
S+VQF+C+E Y LQG+K ITC +++++FAAWSDHRPVC+ + C ++L+GPSG TSPNFP
Sbjct: 466 STVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFP 525
Query: 423 IQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTS 482
QYD+NA CVW+ITA+N +KVI++ FEEFDLE GYDTLT+GDGG+ GD +TVL +LTG+
Sbjct: 526 FQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSF 585
Query: 483 VPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDT 542
VPDLIVS + QMWL QTD S S+GFK +Y+EIE+ SCGDPG P YG REG F + D
Sbjct: 586 VPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDV 645
Query: 543 LKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHL 602
L+FECQ FEL+G+K+I CQ+NNQWSA P C+F C NFT+P G VLSP+YPE YGN+L
Sbjct: 646 LRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNL 705
Query: 603 HCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGH 662
+C+W I++ P SRIHL+FND D+E QFDFL +KDG + E+P+LGTF+G ++PS +TS+ H
Sbjct: 706 NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSH 765
Query: 663 VARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFL 722
+ RLEFQ DHS RGFNIT+ TF HNECPDPG+P+N +RFGD+ QLGSSIS +C+EGF+
Sbjct: 766 ILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFI 825
Query: 723 GTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVI 782
TQG+ETITC+L +G V+W+ + +C APCGGH ++PSG ILSPGWPG+YKD+L+C WVI
Sbjct: 826 KTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVI 885
Query: 783 EAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLF 842
EA+PG+ IKITF+RF+TE+NYD LEV DG +PL+G Y+GTQVPQFL S+SN++YLLF
Sbjct: 886 EAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLF 945
Query: 843 STDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDG 902
+TD S S+ GF++ YE++T+ + CLDPGIPV+G+R+G+DF +G+ V+FSCDSGY LS
Sbjct: 946 TTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHE 1005
Query: 903 EPLECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGV 962
EPL CE N WS LP+C+ALCGG ++G SGTILSPG+P+FYPN+LNCTW ++ +HGKGV
Sbjct: 1006 EPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1065
Query: 963 FFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSM 1022
F FHTFHLE HDYLLITENGSFTQPL +LTGS LP I+AGLYGNF AQ+RFISDFS+
Sbjct: 1066 QFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSI 1125
Query: 1023 SYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGG 1082
SYEGFNITFSEY+LEPCE+P +P Y R G FG+GDTLTFSC GYRLEGT+ I CLGG
Sbjct: 1126 SYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG 1185
Query: 1083 RRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARA 1142
RR+WS+PLPRCVAECG S T +G LLSPN+P+NY NNHECIYSIQ Q GKGI + AR
Sbjct: 1186 GRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISART 1245
Query: 1143 FELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELH 1202
F L++GDVLK+YDG + + LLG F+ + M G+TL+STS+ LWL+F +D E T +GF+L
Sbjct: 1246 FHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLV 1305
Query: 1203 FSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDR 1262
++SFEL CEDPG P+FGYK+ D+GHFAGS++ + C+PGY+L GS L C++GERR WD
Sbjct: 1306 YTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY 1365
Query: 1263 PLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEV 1322
PLP+C+AECGG +GE SG++LSPGYP PY++NL C+W IE + G + L FL FDTE
Sbjct: 1366 PLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS 1425
Query: 1323 HDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTA 1382
HD+LR+WDGP E+ +LLKE+SG +P+ +HST N V +QF TDF+ SK GFAIQFS S A
Sbjct: 1426 HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1485
Query: 1383 TSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCI 1442
T+C DPG+P NG+R+GD E GD+ VFQCDPGY LQG I+C+++ENR+FWQPSPP CI
Sbjct: 1486 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI 1545
Query: 1443 APCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIY 1502
APCGG+LTG SG ILSPN+P PYP ++CDW +TV+ DYVI+L F F++EP YDFL+IY
Sbjct: 1546 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1605
Query: 1503 DGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPG 1562
DG DS SPLIGSF S+LP RIESSSN++ LAFRSD SVS GF ++Y RESCFDPG
Sbjct: 1606 DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPG 1665
Query: 1563 SIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQ 1622
+I NGTR+G D KLGS+VTYYC GY ++G STL+CI+G DG+P WN P C APCG +
Sbjct: 1666 NIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSR 1725
Query: 1623 YVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHS 1682
GS+G VLSPNYP+NY+ G C+Y + VPK++VVFGQF FF T+L+DVVEV+DG +Q S
Sbjct: 1726 STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQS 1785
Query: 1683 RLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPEPR 1742
LLSSLSGSH+GESLPL++ NQ+ I+F++ G A+GFHFVYQAVPRTS+TQCSSVPEPR
Sbjct: 1786 SLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPR 1845
Query: 1743 YGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTE 1802
+G+R+G++F+VG+ V F+CN GY L GS I C VP +LAQWN S PTC+VPCGG LT+
Sbjct: 1846 FGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTK 1905
Query: 1803 RRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTM 1862
R+GTILSPG+PEPY N+LNCVWKI VPEGAGIQ+QVVSF TE NWDSL+ +DG DN
Sbjct: 1906 RKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPR 1965
Query: 1863 LGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTG 1922
LGS+SGTT+P LLNSTSN LYL+F SDISVSAAGFHLEY +GL SCPEP PS+G+K G
Sbjct: 1966 LGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG 2025
Query: 1923 ERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVILSP 1982
+RY+V DVVSFQC+ GY+LQGH+HI+CMPG VRRWNYP P+C+AQCGG + + GVILSP
Sbjct: 2026 DRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSP 2085
Query: 1983 GFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSE 2042
GFPGNYPS++DC+W I LP+GFG H+QF+NFSTE HDY+E+R+G ETS ++GR SG +
Sbjct: 2086 GFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ 2145
Query: 2043 LPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSFLRGFDLSELERTNSTPP 2102
+PSSL ST+HET++YFHSD+SQN+ GF + YQ
Sbjct: 2146 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQ---------------------------- 2177
Query: 2103 VAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLT 2162
AY+LQ CPDP PF NG V G + VGQ+++FEC PGY L G+ LT
Sbjct: 2178 --------------AYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALT 2223
Query: 2163 CQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRL 2222
C HG +RNW+HPLP+CE CGGNIT+ NGT+YSPG+P Y + QDC WL+ VP G+G+ +
Sbjct: 2224 CLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYI 2283
Query: 2223 NLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIF 2282
N ++LQTEP DFIT+WDGP Q +P++G F+ + A ++V S+SNQ+L+KFH D T G F
Sbjct: 2284 NFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFF 2343
Query: 2283 AIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYL 2342
+++ AY L C PP +PNAE++TE++EF IGDI+RY+CLPGFTLVGN ILTC+LG L
Sbjct: 2344 VLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERL 2403
Query: 2343 QFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYF 2402
Q +G PP+C+V CP NEL DSTGVILS YP SYP Q C+W + VE YNI++ VE+F
Sbjct: 2404 QMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFF 2463
Query: 2403 LSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIR 2462
+EK++D +++DGP+ QSP+L +LSG+YS+ +TS+ + V+L+WS+DH N+KGF+IR
Sbjct: 2464 QTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIR 2523
Query: 2463 YSAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEA 2522
Y A YCS P +P HG+I+ QT Q + + C+ G+RLVG S A+C + GYH W
Sbjct: 2524 YIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAP 2583
Query: 2523 IPLCQALSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNR 2582
+P CQA+SCG+P+AP NG + +Y VGT+ Y C++GY L + TA C G WSN
Sbjct: 2584 VPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNH 2643
Query: 2583 NVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANG 2642
N P+CV VTCP ++S +EHGRWR++ + Y+++ +++ CDPGY+ G I C NG
Sbjct: 2644 NKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNG 2703
Query: 2643 KWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANG 2702
WS + P C+IISCGELP PPNG++IGT + YG+TAIF+C+ G+ LVGS VREC+++G
Sbjct: 2704 TWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSG 2763
Query: 2703 LWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHW 2762
LWS SE RCLAGHCG PE IVNG + GENY YR +VVYQCN GFRLIG SVRICQQDH+W
Sbjct: 2764 LWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNW 2823
Query: 2763 SGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTG 2822
SG+ P CV VSCGHPGSP + + SG+ + VV +SC + G + C + W+
Sbjct: 2824 SGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSH 2883
Query: 2823 SLPHCSGTSVGVCGDPGIPAHGIRLG----DSFDPGTVMRFSCEAGHVLRGSSERTCQAN 2878
P C V C DPGIPA+ R +F GTV+ + C G+ L GSS CQ N
Sbjct: 2884 PPPMC---KVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPN 2940
Query: 2879 GSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNG 2938
G W PEC +I CG+PG P NA V+ + F S++ Y C G SR C +NG
Sbjct: 2941 GQWDKPLPECIMIDCGHPGVPPNA-VLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG 2999
Query: 2939 TWTGSDPEC---LVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCT 2995
W+GS P C CGDPG P +G R ++FR TV Y C GY++ H +C
Sbjct: 3000 HWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYIL--HGSEERTCL 3057
Query: 2996 KDRTWNGTKPVCKALMCKPPPLIPNGKVVGSD-FMWGSSVTYACLEGYQLSLPAVFTCEG 3054
+ +W G +P CKA+ C P NGKV D + SSV Y+C+EGY LS P+V C
Sbjct: 3058 ANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTA 3117
Query: 3055 NGSWTGELPQCFPVFCGDPGVPSRGRREDRGFSYRSSVSFSCHP--PLVLVGSPRRFCQS 3112
NG+W+G LP C + CGDPG+P+ G R + +VS+ C P + L GS R C
Sbjct: 3118 NGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTI 3177
Query: 3113 DGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTC 3172
+GTWSG P+C TC P G + + G ++ + C GY L TC
Sbjct: 3178 NGTWSGVMPTC---RAVTCPTPPQISNG-RLEGTNFDWGFSISYICSPGYELSFPAVLTC 3233
Query: 3173 LPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFS-----LKGGS 3227
+ N TWSG P C+P C P P G + IY + FS + GS
Sbjct: 3234 VGNGTWSGEVPQCLPKFCGDPGIPAQGK-------REGKSFIYQSEVSFSCNFPFILVGS 3286
Query: 3228 EHRTCKADGSWTGKPPICLEVRPSGRPINTAREPP 3262
R C+ADG+W+G P C+E P T+ E P
Sbjct: 3287 STRICQADGTWSGSSPHCIE------PTQTSCENP 3315
Score = 2254 bits (5841), Expect = 0.0
Identities = 1256/3413 (36%), Positives = 1815/3413 (53%), Gaps = 249/3413 (7%)
Query: 136 SHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
S+ C +PG NG + GS F+LG V++SC+ + L+G +TC +E A W P
Sbjct: 443 SNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 502
Query: 196 CRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILA-ELGDTIALVFIDFQLEDGYD 254
C+ CG L+G SG +SP+FP +Y +NA C W I A I + F +F LE GYD
Sbjct: 503 CKVK-TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 561
Query: 255 FLEV-----TGTEGSSLW-FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQ 308
L + G + L TG+ +P ++S + + LH +D + GF Y K+
Sbjct: 562 TLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY---KE 618
Query: 309 IELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFT 368
IE +S C DPG P G R G F ++F
Sbjct: 619 IEKES-----------------------------CGDPGTPLYGIREGDGFSNRDVLRFE 649
Query: 369 CNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNN 428
C G++L G K I C + + WS + P+C C ++ P G + SP++P Y NN
Sbjct: 650 CQFGFELIGEKSIVCQENNQ----WSANIPIC-IFPCLSNFTAPMGTVLSPDYPEGYGNN 704
Query: 429 AHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIV 488
+C+W I + +P I L+F +FDLE +D L V DG D + +L TG VP +
Sbjct: 705 LNCIWTIIS-DPGSRIHLSFNDFDLESQFDFLAVKDG--DSPESPILGTFTGAEVPSHLT 761
Query: 489 STNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQ 548
S +H + L FQ D S S GF +Y C DPGIP RR G F G ++ C+
Sbjct: 762 SNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICE 821
Query: 549 PAF-ELVGQKAITC---QKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHC 604
F + G + ITC WS P C C +F++PSGV+LSP +P Y + L+C
Sbjct: 822 EGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNC 881
Query: 605 VWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVA 664
W+I A P I + F E +D L + DG +P+LG+++G Q+P + SS +
Sbjct: 882 EWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFI 941
Query: 665 RLEFQTDHSTGKRGFNITFTTFRHN--ECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFL 722
L F TD+S GF I + + N C DPG+PV+G+R+G +GS++SF CD G+
Sbjct: 942 YLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYR 1001
Query: 723 GTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVI 782
+ E + C E + W+ + C+A CGG + PSGTILSPG+P FY ++L+C W +
Sbjct: 1002 LSH-EEPLLC---EKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTV 1057
Query: 783 EAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNY----L 838
+ G ++ F F E ++D L + + +++ PL + G+ +P I+ Y
Sbjct: 1058 DVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLT-GSDLPP-TINAGLYGNFRA 1115
Query: 839 YLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYT 898
L F +D S S GF + + L+ C DPGIP G R G +F +G +TFSC SGY
Sbjct: 1116 QLRFISDFSISYEGFNITFSEYNLEP--CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYR 1173
Query: 899 LSDGEPLECEPNFQ--WSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIET 956
L + C + WS LP C A CG + G +LSP +P Y NN C + I+
Sbjct: 1174 LEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQV 1233
Query: 957 SHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQ--- 1013
GKG+ + TFHL G + T L TG+ + GL + T+
Sbjct: 1234 QAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASM-----RGLTLSSTSNQLW 1288
Query: 1014 VRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQ-FGVGDTLTFSCFPGYRLE 1072
+ F SD + EGF + ++ ++L CE+P +P + + Q G T+ + C PGY L
Sbjct: 1289 LEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLH 1348
Query: 1073 GTARITCLGGRRRLWSSPLPRCVAECGNSVTG-TQGTLLSPNFPVNYNNNHECIYSIQTQ 1131
G++ + C+ G RR W PLP C+AECG G + G +LSP +P Y+NN C++ I+
Sbjct: 1349 GSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVD 1408
Query: 1132 PGKGIQLKARAFELSEG-DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFIT 1190
PG + L+ AF+ D+L+V+DG + LL S S ++ ++ST + + + F T
Sbjct: 1409 PGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGS-LIPEGIHSTLNIVTIQFDT 1467
Query: 1191 DAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEEL 1250
D + GF + FSS C DPG P G + + +G G +V F CDPGY L+G E +
Sbjct: 1468 DFYISKSGFAIQFSSSVATACRDPGVPMNGTR-NGDGREPGDTVVFQCDPGYELQGEERI 1526
Query: 1251 LCLSGERRT-WDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCT 1309
C+ E R W P C+A CGG + G SG +LSP +P PY H+ +C WTI A
Sbjct: 1527 TCIQVENRYFWQPSPPVCIAPCGGNLTGS-SGFILSPNFPHPYPHSRDCDWTITVNADYV 1585
Query: 1310 IGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTS 1369
I L F+ F E +D L I+DGP + L+ LP+ + S+ N++ L F +D S
Sbjct: 1586 ISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVS 1645
Query: 1370 KQGFAIQFSVSTATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIE 1429
GF +++ SC DPG NG+R G ++ G + + CD GY LQG + ++C+ +
Sbjct: 1646 YTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGD 1705
Query: 1430 N-RFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFN 1488
+ R W + P+C APCG TG G +LSPNYP+ Y G C + + V ++V+ F
Sbjct: 1706 DGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFV 1765
Query: 1489 IFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIE-SSSNSLFLAFRSDASVSNAGFV 1547
F +D + +YDG S L+ S GS + SS N + + F S ++ GF
Sbjct: 1766 FFQTSL-HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFH 1824
Query: 1548 IDYTENPRESCFDPGSIKN---GTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDG 1604
Y PR S S+ G R+G++ +GSSV + C+ GY + G+ + C P+
Sbjct: 1825 FVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNS 1884
Query: 1605 KPVWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFF 1664
WN+ P C PCGG G +LSP YP+ Y + C++ +TVP+ + Q F
Sbjct: 1885 LAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSF 1944
Query: 1665 HTALN-DVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFV 1723
T N D ++ +DG ++ L S SG+ T L +TSN + + F + A GFH
Sbjct: 1945 ATEHNWDSLDFYDGGDNNAPRLGSYSGT-TIPHLLNSTSNNLYLNFQSDISVSAAGFHLE 2003
Query: 1724 YQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALA 1783
Y A+ S C P G ++G + VG +V F+C+ GY+LQG I C+P G +
Sbjct: 2004 YTAIGLDS---CPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMP--GPVR 2058
Query: 1784 QWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVT 1843
+WN P C+ CGG +++ G ILSPGFP Y +SL+C W I +P G G+ +Q V+F T
Sbjct: 2059 RWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFST 2118
Query: 1844 EQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 1903
E D LEV G+ T T++G SG +P+ L ST+++ L+F+SD S + GFH+ Y+
Sbjct: 2119 ETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2178
Query: 1904 VGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPL 1963
L SCP+P NG G + V +SF+C PGY L G++ ++C+ G R WN+P P
Sbjct: 2179 YQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2238
Query: 1964 CIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIE 2023
C A CGG + M G I SPG+P YP+ DC W + +P G G +I F TEP +D+I
Sbjct: 2239 CEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFIT 2298
Query: 2024 IRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQIS 2083
+ +GP + S +G+FSG+ S+ STS++ + FHSD + + GF + L+Y
Sbjct: 2299 VWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS--GFFV----LSY----- 2347
Query: 2084 SFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANG--IVRGAGYNV 2141
AY+L+ C P P N + + +
Sbjct: 2348 --------------------------------HAYQLRVCQPPPPVPNAEILTEDDEFEI 2375
Query: 2142 GQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNIT--SSNGTVYSPGFP 2199
G + ++CLPG+ L G+ +LTC+ G D P C+V C N S G + SPG+P
Sbjct: 2376 GDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYP 2435
Query: 2200 SPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKK 2259
Y + Q C W I+V G+ + + + QTE D + ++DGP +P L + +
Sbjct: 2436 DSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSA 2495
Query: 2260 -TVQSSSNQVLLKFHRDAATGGI-FAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDI 2317
+ S+ ++V L++ D F I + A+ C P P+ ++++ + +
Sbjct: 2496 FNITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCSTPESPPHGYIISQTGG-QLNSV 2551
Query: 2318 VRYRCLPGFTLVGNEILTCKLGTY--LQFEGPPPICE-VHCPTNELLTDSTGVILSQSYP 2374
VR+ C GF LVG C+ +Y ++ P P C+ + C + T+ G++ +
Sbjct: 2552 VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNG-GILTT---- 2606
Query: 2375 GSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAP 2434
DY + V YF ++ LS
Sbjct: 2607 -----------------DYLVGTRVTYFCNDGY------------------RLSSKELTT 2631
Query: 2435 LIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAP-LHGFILGQTSTQPGGSIH- 2492
+ S WS+ + P C + P ++ FIL + H
Sbjct: 2632 AVCQSDGT-----WSNHN-----------KTPRCVVVTCPSINSFILEHGRWRIVNGSHY 2675
Query: 2493 -------FGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGK 2545
F C+ GY +G + C P G W P CQ +SCG P NG G
Sbjct: 2676 EYKTKVVFSCDPGYHGLGPASIECL--PNGTWSWRNERPYCQIISCGELPTPPNGNKIGT 2733
Query: 2546 EYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTC--PDVSSISVEH 2603
+ + G+ A+++C G+ L A ECL +GLWS +C+ C P++ + +
Sbjct: 2734 QTSYGSTAIFTCDLGFMLVGSA--VRECLSSGLWSESET--RCLAGHCGIPEL----IVN 2785
Query: 2604 GRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPI 2663
G+ + Y ++ ++ C+PG+ G V CQ + WS P+C +SCG
Sbjct: 2786 GQ---VIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWS--GQLPSCVPVSCGHPGS 2840
Query: 2664 PPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIV 2723
P G G + FSCN GY + G +C AN WS C +C P
Sbjct: 2841 PIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPA 2900
Query: 2724 NGH----INGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGS 2779
N I N++Y V Y CN G+ L G SV ICQ + W P C+++ CGHPG
Sbjct: 2901 NSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGV 2960
Query: 2780 PPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPG 2839
PP++ +SG+ YT G+ V YSC GKR+L+G S+R C L+GHW+GS PHCSG + G CGDPG
Sbjct: 2961 PPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPG 3020
Query: 2840 IPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTP 2899
P HG R +F + +R++C+ G++L GS ERTC ANGSW+G QPEC + CGNPGT
Sbjct: 3021 TPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTT 3080
Query: 2900 SNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPA 2959
+N +V DG FSSS++Y C EGY +G R C+ NGTW+G+ P C +I+CGDPGIPA
Sbjct: 3081 ANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPA 3140
Query: 2960 NGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIP 3019
NGLR G+D+ + V+Y C PGY ME + + +CT + TW+G P C+A+ C PP I
Sbjct: 3141 NGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQIS 3200
Query: 3020 NGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRG 3079
NG++ G++F WG S++Y C GY+LS PAV TC GNG+W+GE+PQC P FCGDPG+P++G
Sbjct: 3201 NGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQG 3260
Query: 3080 RREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQF 3139
+RE + F Y+S VSFSC+ P +LVGS R CQ+DGTWSG+ P CI+PT T+C +PGVP+
Sbjct: 3261 KREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRH 3320
Query: 3140 GIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHA 3199
G QNN+ G+QVGS V F C+KG+LLQGSTTRTCLP+LTWSG P+C+PH C+QPETP HA
Sbjct: 3321 GSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHA 3380
Query: 3200 NVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRPI---- 3255
NV +DLPS GYTLIY+CQ GF L GG+EHR C++D +WTGK PIC +G I
Sbjct: 3381 NVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC----EAGSKILVKD 3436
Query: 3256 -NTAREPPLTQALIPGDVFAKNSLWKGAYEYQGKKQPAMLRVTGFQVANSKVNATMIDHS 3314
A P + +P DVFA+N +WKG+Y ++G+KQP L VT F + +VNAT + +S
Sbjct: 3437 PRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNAT-LSNS 3495
Query: 3315 GVELHLAGTYKKEDFHLLLQVYQITGPVEIFMNKFKDDHWALDGHVSSESSGATFIYQGS 3374
+EL L+G YK ++ L+L++Y I P + K K+++WA+DG VS+E GAT+++QG
Sbjct: 3496 NMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGF 3555
Query: 3375 VKGQGFGQFGFQRLDLRLLESDPESIGRHFASNSSSVAAAILVPFIALIIAGFVLYLYKH 3434
++G+ +GQFG QRL L + E S H +NSSSVA AILVPF ALI AGF YLYK
Sbjct: 3556 IQGKDYGQFGLQRLGLNMSEGSNSSNQPH-GTNSSSVAIAILVPFFALIFAGFGFYLYKQ 3614
Query: 3435 RRRPKVPFNGYAGHENTNVRATFENPMYDRNIQPTDIMASEAEFTVSTVCTAV 3487
R PK + G + HEN N +A FENPMYD N + + A + ++TVCT V
Sbjct: 3615 RTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV 3667
Score = 1561 bits (4043), Expect = 0.0
Identities = 1010/3045 (33%), Positives = 1489/3045 (48%), Gaps = 231/3045 (7%)
Query: 17 HHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHR-IQLVFQSFALEE 75
H P + C L GP+GT SP FP+ Y + A C W ITA ++ IQ+ F+ F LE
Sbjct: 499 HRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEI 558
Query: 76 DFDVLSVFDGPP--QPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEV 133
+D L++ DG P + LTG +P IVS ++ + L L +D +V + GF Y+
Sbjct: 559 GYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKE 618
Query: 134 LPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPL 193
+ +CG+PG GI++G F+ D +R+ C GF L G + C ++ W +
Sbjct: 619 IEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ----WSANI 674
Query: 194 PSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGY 253
P C C G + SP +P Y NN +C WTI+++ G I L F DF LE +
Sbjct: 675 PICIFP--CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQF 732
Query: 254 DFLEVTGTEGSSL----WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQI 309
DFL V + FTGA +P+ + S+ + LRL F +D + RGF+ Y
Sbjct: 733 DFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYN----- 787
Query: 310 ELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTC 369
+ GHN CPDPGIP +R G +F+LGSS+ C
Sbjct: 788 ---------------------------TFGHNECPDPGIPINARRFGDNFQLGSSISVIC 820
Query: 370 NEGY-DLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNN 428
EG+ QG++ ITC+ + D WS P C A C H PSG+I SP +P Y ++
Sbjct: 821 EEGFIKTQGTETITCI-LMDGKVMWSGLIPKCGAP-CGGHFSAPSGVILSPGWPGYYKDS 878
Query: 429 AHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIV 488
+C W+I A P IK+ FE F E YD L V DG +L GT VP +
Sbjct: 879 LNCEWVIEA-EPGHSIKITFERFQTELNYDVLEVHDG--PNLLSPLLGSYNGTQVPQFLF 935
Query: 489 STNHQMWLLFQTDGSGSSLGFKASYEEIEQG--SCGDPGIPAYGRREGSRFHHGDTLKFE 546
S+++ ++LLF TD S S+ GFK YE + SC DPGIP +GRR G F G T+ F
Sbjct: 936 SSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFS 995
Query: 547 CQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVW 606
C + L ++ + C+KN+ WS P C C + PSG +LSP YPE Y N L+C W
Sbjct: 996 CDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTW 1055
Query: 607 LILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSS---GHV 663
+ + F+ +E D+L+I + + P L +G+ LP +I +
Sbjct: 1056 TVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQP-LARLTGSDLPPTINAGLYGNFR 1114
Query: 664 ARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLG 723
A+L F +D S GFNITF+ + C DPG+P G R G + +G +++F C G+
Sbjct: 1115 AQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYR- 1173
Query: 724 TQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIE 783
+G+ I C L G VW++ + RC A CG T+ G +LSP +P Y++ C + I+
Sbjct: 1174 LEGTSEIIC-LGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQ 1232
Query: 784 AQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQF-LISTSNYLYLLF 842
Q G I I+ F D L++ DG+ + L+G + G + L STSN L+L F
Sbjct: 1233 VQAGKGINISARTFHLAQG-DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEF 1291
Query: 843 STDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGND-FYVGALVTFSCDSGYTLSD 901
++D +D GFQL Y + L HC DPGIP G + + + G+ + + C+ GYTL
Sbjct: 1292 NSDTEGTDEGFQLVYTSFELS--HCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHG 1349
Query: 902 GEPLECEPNFQ--WSRALPSCEALCGGFIQG-SSGTILSPGFPDFYPNNLNCTWIIETSH 958
L+C + W LPSC A CGG +G SSG ILSPG+P Y NNL C W+IE
Sbjct: 1350 SSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDP 1409
Query: 959 GKGVFFTFHTFHLESGHDYLLITENGSFTQPL-RQLTGSRLPAPISAGLYGNFTAQVRFI 1017
G V F F E+ HD L + + L ++++GS +P I + L ++F
Sbjct: 1410 GNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLN---IVTIQFD 1466
Query: 1018 SDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARI 1077
+DF +S GF I FS C +P VP R G GDT+ F C PGY L+G RI
Sbjct: 1467 TDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERI 1526
Query: 1078 TCLGGRRR-LWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGI 1136
TC+ R W P C+A CG ++TG+ G +LSPNFP Y ++ +C ++I I
Sbjct: 1527 TCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVI 1586
Query: 1137 QLKARAFELSEG-DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENT 1195
L +F + D L +YDG ++++ L+G F S++ + S+S+++ L F +D +
Sbjct: 1587 SLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE-RIESSSNTMHLAFRSDGSVS 1645
Query: 1196 SKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSG 1255
GF L + + C DPG G ++ + + GS+V++ CD GY L+G L C+ G
Sbjct: 1646 YTGFHLEYKAKLRESCFDPGNIMNGTRLGMD-YKLGSTVTYYCDAGYVLQGYSTLTCIMG 1704
Query: 1256 E--RRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLH 1313
+ R W+R LP+C A CG G G VLSP YP Y NC+++I +
Sbjct: 1705 DDGRPGWNRALPSCHAPCGSRSTGS-EGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQ 1763
Query: 1314 FLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLH-STFNSVVLQFSTDFFTSKQG 1372
F+ F T +HDV+ ++DGP + LL LSG + L S+ N + ++F++ + +G
Sbjct: 1764 FVFFQTS-LHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKG 1822
Query: 1373 FAIQFSV---STATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIE 1429
F + +++T C+ P+ G R G+ + G S +F C+PGY L GS I C +
Sbjct: 1823 FHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVP 1882
Query: 1430 NRFF-WQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFN 1488
N W S PTCI PCGG LT G ILSP YPEPY C WK+TV I +
Sbjct: 1883 NSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV 1942
Query: 1489 IFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVI 1548
F E +D L YDG D+ +P +GS+ G+ +P + S+SN+L+L F+SD SVS AGF +
Sbjct: 1943 SFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHL 2002
Query: 1549 DYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVW 1608
+YT +SC +P + +G ++G +G V++ C GY ++G S ++C+ GP + W
Sbjct: 2003 EYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRR--W 2060
Query: 1609 NNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHT-A 1667
N P P+C A CGG GV+LSP +P NY S C + + +P + V QF F T
Sbjct: 2061 NYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET 2120
Query: 1668 LNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAV 1727
++D +EV G S+ S ++ LSG SL +T+++ + F + +GFH VYQA
Sbjct: 2121 IHDYLEVRSGSSETSTVIGRLSGPQIPSSL-FSTTHETSLYFHSDYSQNKQGFHIVYQAY 2179
Query: 1728 PRTSATQCSSVPEPR---YGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQ 1784
Q S P+PR G +G+DF+VG + FEC GY L G+ + CL G
Sbjct: 2180 ------QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLH--GVSRN 2231
Query: 1785 WNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTE 1844
WN P C CGGN+T GTI SPG+P+ Y N +C W + VP G GI I TE
Sbjct: 2232 WNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTE 2291
Query: 1845 QNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 1904
+D + V+DG D +G FSG T + STSNQ+ + F+SD + S F L Y
Sbjct: 2292 PIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGF-FVLSYHAY 2350
Query: 1905 GLSSC-PEPAVPSNGVKT-GERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPP 1962
L C P P VP+ + T + + + D++ +QC PG+ L G+A ++C G + + PP
Sbjct: 2351 QLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPP 2410
Query: 1963 LCIAQCGGTVEEME--GVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHD 2020
+C C ++ GVILSPG+P +YP+ C+W I++ G+ + F TE D
Sbjct: 2411 VCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFD 2470
Query: 2021 YIEIRNGPYETSRMMGRFSGSELPS-SLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYS 2079
+++ +GP S ++ SG + ++ S HE + + +DH N+ GF++ Y S
Sbjct: 2471 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2530
Query: 2080 ---------------HQISSFL-----RGFDLSELERTNSTPPVAASYVWDLD-PGCEAY 2118
Q++S + RGF L + WD P C+A
Sbjct: 2531 TPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI 2590
Query: 2119 ELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWD--HPLP 2176
C P+ NG + Y VG VT+ C GY+L+ + T ++ W + P
Sbjct: 2591 ---SCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTP 2647
Query: 2177 KCEVPCGGNITS----------SNGTVY----------SPGFPSPYSSSQDCV----WLI 2212
+C V +I S NG+ Y PG+ +S +C+ W
Sbjct: 2648 RCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSW 2707
Query: 2213 TVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKF 2272
+ ++ L T P+G+ I G Q + +FT + V S+
Sbjct: 2708 RNERPYCQIISCGELPTPPNGNKI----GTQTSYGSTAIFTCDLGFMLVGSAV------- 2756
Query: 2273 HRDAATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNE 2332
R+ + G+++ + + C P ++ N +V+ EN + D V Y+C PGF L+G+
Sbjct: 2757 -RECLSSGLWSESETRCLAGHCGIPELIVNGQVIGEN--YGYRDTVVYQCNPGFRLIGSS 2813
Query: 2333 ILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPD 2392
+ C+ + G P C V +S +PGS +T
Sbjct: 2814 VRICQQDH--NWSGQLPSC---------------VPVSCGHPGSPIYGRTSGNGFNFNDV 2856
Query: 2393 YNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALS------------------GNYSAP 2434
S + Y + + + S P+ K ++ GN++
Sbjct: 2857 VTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYG 2916
Query: 2435 LIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSL-----PRAPLHGFILGQTSTQPGG 2489
+V N Y + S + + P C + P P + + G+ T G
Sbjct: 2917 TVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTF-GS 2975
Query: 2490 SIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQ---ALSCGLPEAPKNGMVFGKE 2546
++H+ C L+G S C + WS + P C +CG P P +G
Sbjct: 2976 TVHYSCTGKRSLLGQSSRTCQLNGH----WSGSQPHCSGDATGTCGDPGTPGHGSRQESN 3031
Query: 2547 YTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRW 2606
+ + Y+C GY L E T CL G W+ R P+C V C + + + +G+
Sbjct: 3032 FRTKSTVRYACDTGYILHGSEERT--CLANGSWTGRQ--PECKAVQCGNPGTTA--NGKV 3085
Query: 2607 RLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPN 2666
I T F + ++ C GY +G V +C ANG WS + P C IISCG+ IP N
Sbjct: 3086 FRIDGT--TFSSSVIYSCMEGYILSGPSVRQCTANGTWS--GTLPNCTIISCGDPGIPAN 3141
Query: 2667 GHRIGTLSVYGATAIFSCNSGYT--LVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVN 2724
G R G V G + C GYT L GSR+R C NG WSG C A C TP I N
Sbjct: 3142 GLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISN 3201
Query: 2725 GHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQ 2784
G + G N+ + S+ Y C+ G+ L +V C + WSG+ P C+ CG PG P +
Sbjct: 3202 GRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGK 3261
Query: 2785 MSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHG 2844
G S+ + V +SC LVG+STR+C DG W+GS PHC + C +PG+P HG
Sbjct: 3262 REGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHG 3321
Query: 2845 IRLGD-SFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNAR 2903
+ F G+V++F C+ GH+L+GS+ RTC + +WSG QPEC SC P TP++A
Sbjct: 3322 SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHAN 3381
Query: 2904 VVFSDGLVFSSSIVYECREGYY-ATGLLSRHCSVNGTWTGSDPEC 2947
VV D +++Y C+ G++ A G R C + TWTG P C
Sbjct: 3382 VVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC 3426
Score = 937 bits (2423), Expect = 0.0
Identities = 762/2585 (29%), Positives = 1118/2585 (43%), Gaps = 348/2585 (13%)
Query: 752 CGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDG 811
CGG L +GTI SPG+P Y + +C WVI A+ I+I F F E YD L + DG
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
Query: 812 RTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPG 871
+ G +P + ST + L ++D + S GF++ YE LQS C +PG
Sbjct: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYE--ELQSSSCGNPG 142
Query: 872 IPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPN----FQWSRALPSCEA--LCG 925
+P G +G F VG + +SC +GY L L C N W +P C A CG
Sbjct: 143 VPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACG 202
Query: 926 GFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGS 985
G ++GSSG I SP FP+ Y NN +CTW I G + F F +E +DYL I GS
Sbjct: 203 GTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI--EGS 260
Query: 986 FTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNI----------TFSEYD 1035
P L+G +P PI + ++ F++D + Y GF+ T S +
Sbjct: 261 -EPPTIWLSGMNIPPPI---ISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGE 316
Query: 1036 LEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCV 1095
LE A ++ ++T E ++T L +S L
Sbjct: 317 LEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLR------NSGLDPNT 370
Query: 1096 AECGNS--VTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKV 1153
++ G S TQ T P E + + + K I K+R F K+
Sbjct: 371 SKDGLSPHPADTQSTRRRPRHAEQIERTKE-LAVVTHRVKKAIDFKSRGF--------KL 421
Query: 1154 YDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCED 1213
+ G +NS + FS G+ T+S+L C D
Sbjct: 422 FPGKDNSNK----FSILNEGGI---KTASNL--------------------------CPD 448
Query: 1214 PGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLC--LSGERRTWDRPLPTC-VAE 1270
PG P+ G ++ + GS+V FSCD Y L+G++ + C ++ W P C V
Sbjct: 449 PGEPENGKRIGSD-FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKT 507
Query: 1271 CGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEA-EAGCTIGLHFLVFDTEEVHDVLRIW 1329
CG ++G SG SP +P Y+ N C+W I A I ++F FD E +D L I
Sbjct: 508 CGSNLQGP-SGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIG 566
Query: 1330 DGPV--ESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCND 1387
DG + +L+ L+G +P + S + + L TD GF + + SC D
Sbjct: 567 DGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGD 626
Query: 1388 PGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGG 1447
PG P G R GD + D F+C G+ L G I C + W + P CI PC
Sbjct: 627 PGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVC---QENNQWSANIPICIFPCLS 683
Query: 1448 DLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDS 1507
+ T P G +LSP+YPE Y C W + P I L FN F+LE +DFL + DG
Sbjct: 684 NFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSP 743
Query: 1508 LSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSIKNG 1567
SP++G+F G+++P + S+S+ L L F++D S+S GF I Y C DPG N
Sbjct: 744 ESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINA 803
Query: 1568 TRVGSDLKLGSSVTYYCHGGY-EVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQYVGS 1626
R G + +LGSS++ C G+ + +GT T++CIL DGK +W+ P C APCGG +
Sbjct: 804 RRFGDNFQLGSSISVICEEGFIKTQGTETITCIL-MDGKVMWSGLIPKCGAPCGGHFSAP 862
Query: 1627 DGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALN-DVVEVHDGHSQHSRLL 1685
GV+LSP +P Y C + + + + F F T LN DV+EVHDG LL
Sbjct: 863 SGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDG----PNLL 918
Query: 1686 SSLSGSHTGESLP---LATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPEPR 1742
S L GS+ G +P ++SN + + F+ GF Y++V + C P
Sbjct: 919 SPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESV-TVNTYSCLDPGIPV 977
Query: 1743 YGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTE 1802
+G+R G DFS+G+ V F C+SGY L + C W+ PTC CGG++
Sbjct: 978 HGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLC----EKNHWWSHPLPTCDALCGGDVRG 1033
Query: 1803 RRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTM 1862
GTILSPG+PE Y NSLNC W + V G G+Q +F E + D L + + T
Sbjct: 1034 PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFT-QP 1092
Query: 1863 LGSFSGTTVPALLNS---TSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGV 1919
L +G+ +P +N+ + + L F SD S+S GF++ + L C +P +P G
Sbjct: 1093 LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGS 1152
Query: 1920 KTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVI 1979
+ G + + D ++F C GY L+G + I C+ G R W+ P P C+A+CG + EG++
Sbjct: 1153 RIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGIL 1212
Query: 1980 LSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFS 2039
LSP +P NY +N +C + I + G G +I F D ++I +G +T+ ++G F+
Sbjct: 1213 LSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-DVLKIYDGKDKTTHLLGAFT 1271
Query: 2040 GSELPS-SLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSFLRGFDLSELERTN 2098
G+ + +L STS++ + F+SD GF+L Y
Sbjct: 1272 GASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY------------------------- 1306
Query: 2099 STPPVAASYVWDLDPGCEAYELQECPDPE-PFANGIVRGAGYNVGQSVTFECLPGYQLTG 2157
++EL C DP P + G+ G ++ + C PGY L G
Sbjct: 1307 -----------------TSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHG 1349
Query: 2158 HPVLTCQHGTNRNWDHPLPKCEVPCGGNIT-SSNGTVYSPGFPSPYSSSQDCVWLITVPI 2216
+L C G R WD+PLP C CGG S+G + SPG+P PY ++ C+W+I V
Sbjct: 1350 SSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDP 1409
Query: 2217 GHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRD- 2275
G+ V L TE S D + +WDGP + L + S+ + + S+ N V ++F D
Sbjct: 1410 GNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDF 1469
Query: 2276 AATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILT 2335
+ FAI FS+ T C P + N + E GD V ++C PG+ L G E +T
Sbjct: 1470 YISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGRE--PGDTVVFQCDPGYELQGEERIT 1527
Query: 2336 C-KLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYN 2394
C ++ ++ PP+C C N LT S+G ILS ++P YP + C W + V DY
Sbjct: 1528 CIQVENRYFWQPSPPVCIAPCGGN--LTGSSGFILSPNFPHPYPHSRDCDWTITVNADYV 1585
Query: 2395 ISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAY 2454
ISL F E YD I+DGP SPL+ + + P + SSSN+++L + SD +
Sbjct: 1586 ISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDS-KLPERIESSSNTMHLAFRSDGSV 1644
Query: 2455 NRKGFKIRYSAPY---CSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTR 2511
+ GF + Y A C P ++G LG + G ++ + C+AGY L G+S C
Sbjct: 1645 SYTGFHLEYKAKLRESCFDPGNIMNGTRLGM-DYKLGSTVTYYCDAGYVLQGYSTLTCIM 1703
Query: 2512 HPQGYHLWSEAIPLCQALSCGLPEAPKNGMV----FGKEYTVGTKAMYSCS--------- 2558
G W+ A+P C A CG G V + K Y+VG +YS +
Sbjct: 1704 GDDGRPGWNRALPSCHA-PCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFG 1762
Query: 2559 EGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQA 2618
+ Q E D P Q + +SS+S H L + Q
Sbjct: 1763 QFVFFQTSLHDVVEVYDG--------PTQQSSL----LSSLSGSHSGESLPLSSGNQITI 1810
Query: 2619 QLML---ICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSV 2675
+ I G+++ Q V R + C +P P G RIG
Sbjct: 1811 RFTSVGPITAKGFHFVYQAVPRTSST---------------QCSSVPEPRFGRRIGNEFA 1855
Query: 2676 YGATAIFSCNSGYTLVGSRVREC--MANGL--WSGSEVRCLAG-------------HCGT 2718
G++ +F CN GY L GS C + N L W+ S C+ G
Sbjct: 1856 VGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGY 1915
Query: 2719 PEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPG 2778
PEP N N + + AG I + V +H+W G
Sbjct: 1916 PEPYDN------NLNCVWKITVPEGAG---IQVQVVSFATEHNWDSLD----FYDGGDNN 1962
Query: 2779 SPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGV--CG 2836
+P SG T + S L S G H T++G+ C
Sbjct: 1963 APRLGSYSG---TTIPHLLNSTSNNLYLNFQSDISVSAAGF------HLEYTAIGLDSCP 2013
Query: 2837 DPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQAN--GSWSGSQP----ECG- 2889
+P P+ GI++GD + G V+ F C+ G+ L+G S TC W+ P +CG
Sbjct: 2014 EPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGG 2073
Query: 2890 --------VISCGNPGT-PSNARVVFSDGLV-----------FSSSIVY---ECREGYYA 2926
++S G PG PS+ ++ L FS+ ++ E R G
Sbjct: 2074 AMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSE 2133
Query: 2927 T----GLLSRHCSVNGTWTGSDPECLVI---------------------NCGDPGIPANG 2961
T G LS + ++ + L +C DP NG
Sbjct: 2134 TSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNG 2193
Query: 2962 LRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTK--DRTWNGTKPVCKALMCKPPPLIP 3019
+GNDF +T++++C PGY + + S L+C R WN P C+AL C
Sbjct: 2194 FVIGNDFTVGQTISFECFPGYTLIGN--SALTCLHGVSRNWNHPLPRCEAL-CGGNITAM 2250
Query: 3020 NGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTC-------EGNGSW-------TGELPQC 3065
NG + GY P C GNG + T +
Sbjct: 2251 NGTIYS--------------PGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDF 2296
Query: 3066 FPVFCG-DPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSG-TQPSC 3123
V+ G D P G + G + SV + + L+ SD T SG S
Sbjct: 2297 ITVWDGPDQNSPQIG--QFSGNTALESVYSTSNQILIKF-------HSDFTTSGFFVLSY 2347
Query: 3124 IDPTLTTC-ADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCL--PNLTWSG 3180
L C P VP I +++G + ++C G+ L G+ TC L G
Sbjct: 2348 HAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDG 2407
Query: 3181 TPPDC 3185
PP C
Sbjct: 2408 APPVC 2412
Score = 929 bits (2402), Expect = 0.0
Identities = 696/2394 (29%), Positives = 1070/2394 (44%), Gaps = 250/2394 (10%)
Query: 16 SHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEE 75
SH + C + GP+GT+ SPG+P YPN NCTWT+ +Q F +F LE+
Sbjct: 1017 SHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLED 1076
Query: 76 DFDVLSVFDGPPQPENLRTRLTGFQLPATI---VSAATTLSLRLISDYAVSAQGFHATYE 132
D L + + + L RLTG LP TI + LR ISD+++S +GF+ T+
Sbjct: 1077 HHDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1135
Query: 133 VLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFP 192
C +PG G + G F +GD + +SC+ G+ LEG + + C G W P
Sbjct: 1136 EYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRR--VWSAP 1193
Query: 193 LPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG 252
LP C A+ CG + GI+ SP++P Y NN +C ++I + G I + F L G
Sbjct: 1194 LPRCVAE--CGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG 1251
Query: 253 YDFLEVTGTEGSSLW----FTGASLPAPVISS-KNWLRLHFTSDGNHRQRGFSAQYQVKK 307
D L++ + + FTGAS+ +SS N L L F SD GF Y
Sbjct: 1252 -DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY---T 1307
Query: 308 QIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRL-GSSVQ 366
EL + C DPGIP+ G ++ GS++
Sbjct: 1308 SFEL-----------------------------SHCEDPGIPQFGYKISDQGHFAGSTII 1338
Query: 367 FTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRG-PSGIITSPNFPIQY 425
+ CN GY L GS + CM + AW P C A C +G SG I SP +P Y
Sbjct: 1339 YGCNPGYTLHGSSLLKCM--TGERRAWDYPLPSCIAE-CGGRFKGESSGRILSPGYPFPY 1395
Query: 426 DNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPD 485
DNN C+W+I ++P ++ L F FD E +D L V DG + D +L ++G+ +P+
Sbjct: 1396 DNNLRCMWMI-EVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDM--LLKEISGSLIPE 1452
Query: 486 LIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKF 545
I ST + + + F TD S GF + +C DPG+P G R G GDT+ F
Sbjct: 1453 GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVF 1512
Query: 546 ECQPAFELVGQKAITC-QKNNQ--WSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHL 602
+C P +EL G++ ITC Q N+ W P C+ C N T SG +LSPN+P Y +
Sbjct: 1513 QCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSR 1572
Query: 603 HCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGH 662
C W I + I LAF +EP +DFL I DG + +P++G+F ++LP I SS +
Sbjct: 1573 DCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSN 1632
Query: 663 VARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFL 722
L F++D S GF++ + C DPG +NG R G +LGS++++ CD G++
Sbjct: 1633 TMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYV 1692
Query: 723 GTQGSETITCVL-KEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWV 781
QG T+TC++ +G WN A+ C APCG T GT+LSP +P Y +C +
Sbjct: 1693 -LQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYS 1751
Query: 782 IEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFL-ISTSNYLYL 840
I + + F F+T + +D +EV DG T + L+ G+ + L +S+ N + +
Sbjct: 1752 IAVPKEFVVFGQFVFFQTSL-HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITI 1810
Query: 841 LFSTDKSHSDIGFQLRYETI-TLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTL 899
F++ + GF Y+ + S C P G+R GN+F VG+ V F C+ GY L
Sbjct: 1811 RFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYIL 1870
Query: 900 SDGEPLECE--PN--FQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIE 955
+ CE PN QW+ +LP+C CGG + GTILSPG+P+ Y NNLNC W I
Sbjct: 1871 HGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKIT 1930
Query: 956 TSHGKGVFFTFHTFHLESGHDYLLITENGSFTQP-LRQLTGSRLPAPI---SAGLYGNFT 1011
G G+ +F E D L + G P L +G+ +P + S LY NF
Sbjct: 1931 VPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQ 1990
Query: 1012 AQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRL 1071
SD S+S GF++ ++ L+ C EP+ P+ I+ G ++ VGD ++F C GY L
Sbjct: 1991 ------SDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSL 2044
Query: 1072 EGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQ 1131
+G + ITC+ G R W+ P+P C+A+CG +++ G +LSP FP NY ++ +C ++I
Sbjct: 2045 QGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLP 2104
Query: 1132 PGKGIQLKARAFELSE-GDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFIT 1190
G G+ L+ F D L+V G++ ++ ++G S ++ +L ST+ L F +
Sbjct: 2105 IGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPS-SLFSTTHETSLYFHS 2163
Query: 1191 DAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEEL 1250
D +GF + + +++L C DP + G+ + ++ G ++SF C PGY+L G+ L
Sbjct: 2164 DYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGND-FTVGQTISFECFPGYTLIGNSAL 2222
Query: 1251 LCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTI 1310
CL G R W+ PLP C A CGG + ++G + SPGYP Y + +C W + G I
Sbjct: 2223 TCLHGVSRNWNHPLPRCEALCGGNITA-MNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGI 2281
Query: 1311 GLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSK 1370
++F V TE ++D + +WDGP ++ + + SG + ++ST N ++++F +DF TS
Sbjct: 2282 YINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS- 2340
Query: 1371 QGFAIQFSVSTATSCNDPGIPQNGS--RSGDSWEAGDSTVFQCDPGYALQGSAEISCVKI 1428
F + + C P N D +E GD +QC PG+ L G+A ++C ++
Sbjct: 2341 GFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTC-RL 2399
Query: 1429 ENRFFWQPSPPTC--IAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALV 1486
R +PP C + P +GVILSP YP+ YP + C W ++V Y I +
Sbjct: 2400 GERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMF 2459
Query: 1487 FNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPG-RIESSSNSLFLAFRSDASVSNAG 1545
F E +D L +YDG + SP++ S G I S+ + +FL + +D + G
Sbjct: 2460 VEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKG 2519
Query: 1546 FVIDYTENPRESCFDPGSIKNGTRVG-SDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDG 1604
F I Y C P S +G + + +L S V + C G+ + G S+ C G
Sbjct: 2520 FRIRYI---AFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYG 2576
Query: 1605 KPVWNNPRPVCTA-PCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAF 1663
W+ P P C A CG ++G +L+ + Y V Y +
Sbjct: 2577 YHAWDAPVPACQAISCGIPKAPTNGGILTTD------------YLVGTRVTYFCNDGYRL 2624
Query: 1664 FHTALNDVVEVHDG-HSQHSRL----------LSSLSGSH------TGESLPLATSNQVL 1706
L V DG S H++ ++S H G T
Sbjct: 2625 SSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFS 2684
Query: 1707 IKFSAKGLAPA------RGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFE 1760
GL PA G P C +P P G ++G+ S G+ F
Sbjct: 2685 CDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFT 2744
Query: 1761 CNSGYALQGSPEIECLPVPGALAQWNVSAPTCVV-PCGGNLTERRGTILSP--GFPEPYL 1817
C+ G+ L GS ECL + W+ S C+ CG G ++ G+ + +
Sbjct: 2745 CDLGFMLVGSAVRECL----SSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVV 2800
Query: 1818 NSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDS-----LEVFDG-ADNTVTMLGSFSGTTV 1871
N ++++ G+ ++I + NW + V G + + S +G
Sbjct: 2801 YQCNPGFRLI---GSSVRI----CQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNF 2853
Query: 1872 PALLNSTSNQLYLHFYSDISVSAAGFHLEY--KTVGLSSCPEPAVPSNGVKTGE----RY 1925
++ + N YL + A + + +C +P +P+N + + +
Sbjct: 2854 NDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNF 2913
Query: 1926 LVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVILSPGFP 1985
VV + C PGY L G + + C P +W+ P P CI ++ G P
Sbjct: 2914 TYGTVVFYDCNPGYFLFGSSVLICQPN--GQWDKPLPECI-------------MIDCGHP 2958
Query: 1986 GNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELPS 2045
G P+ + K FG+ + + + T ++ G +SGS+
Sbjct: 2959 GVPPNAVLSGEKYT----FGSTVHYSCTGKR------SLLGQSSRTCQLNGHWSGSQPHC 3008
Query: 2046 SLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSFLRGFDLSELERTNSTPPVAA 2105
S +T S+ F+ + + Y+ L G + ERT A
Sbjct: 3009 SGDATGTCGDPGTPGHGSRQESNFRTK-STVRYACDTGYILHGSE----ERT-----CLA 3058
Query: 2106 SYVW-DLDPGCEAYELQECPDPEPFANG-IVRGAGYNVGQSVTFECLPGYQLTGHPVLTC 2163
+ W P C+A +C +P ANG + R G SV + C+ GY L+G V C
Sbjct: 3059 NGSWTGRQPECKAV---QCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQC 3115
Query: 2164 QHGTNRNWDHPLPKCE-VPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRL 2222
N W LP C + CG +NG Y + + S C G+ + L
Sbjct: 3116 T--ANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMC------QPGYTMEL 3167
Query: 2223 NLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIF 2282
N S ++T W G T +
Sbjct: 3168 NGSRIRTCTING---TWSGVMPTCRAV--------------------------------- 3191
Query: 2283 AIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTC 2336
CP P + N + E F+ G + Y C PG+ L +LTC
Sbjct: 3192 ----------TCPTPPQISNGRL--EGTNFDWGFSISYICSPGYELSFPAVLTC 3233
Score = 398 bits (1022), Expect = e-110
Identities = 179/279 (64%), Positives = 220/279 (78%)
Query: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG 85
C L G NGT+ESPGFPYGYPN ANCTW I AEE++RIQ+VFQSFALEE++D LS++DG
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
Query: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRL 145
P P N RTRLTGF LP + S + SLRL SD+AVSA GF YE L S +CGNPG
Sbjct: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVP 144
Query: 146 PNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGT 205
P G+ G+ F++GDK+RYSC G+ L+GH LTC A S N+A+WDFP+P CRA+DACGGT
Sbjct: 145 PKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGT 204
Query: 206 LRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSS 265
+RG SGIISSP FP+EYHNNADCTWTI+AE GDTI+L+F DFQ+E+ YD+LE+ G+E +
Sbjct: 205 MRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPT 264
Query: 266 LWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQ 304
+W +G ++P P+IS+KNWLRLHF +D NHR RGFSA YQ
Sbjct: 265 IWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
Score = 193 bits (490), Expect = 3e-48
Identities = 110/313 (35%), Positives = 155/313 (49%), Gaps = 16/313 (5%)
Query: 1793 VVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEV 1852
+ CGG L GTI SPGFP Y N NC W I+ E IQI SF E+ +D L +
Sbjct: 22 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 81
Query: 1853 FDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEP 1912
+DG + +G +P + ST + L SD +VSA GF + Y+ + SSC P
Sbjct: 82 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 141
Query: 1913 AVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVR--RWNYPPPLCIAQ--C 1968
VP GV G R+ V D + + C GY L GH ++C+ +V W++P P+C A+ C
Sbjct: 142 GVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDAC 201
Query: 1969 GGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGP 2028
GGT+ G+I SP FP Y +N DC+W I G + F +F E +DY+EI
Sbjct: 202 GGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSE 261
Query: 2029 YETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ-DLTYSHQISSFLR 2087
T + SG +P ++S + ++F +D + GF YQ T +H S+
Sbjct: 262 PPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTST--- 314
Query: 2088 GFDLSELERTNST 2100
ELE N T
Sbjct: 315 ----GELEEHNRT 323
Score = 184 bits (466), Expect = 2e-45
Identities = 113/318 (35%), Positives = 160/318 (50%), Gaps = 44/318 (13%)
Query: 202 CGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGT 261
CGGTL+G +G I SP FP Y N A+CTW I+AE + I +VF F LE+ YD+L +
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
Query: 262 EGSSLWF----TGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVK 317
F TG LP PV S+K+ L TSD GF Y+ EL+S
Sbjct: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYE-----ELQS---- 135
Query: 318 LMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQG 377
+ C +PG+P +G G+ F +G ++++C GY L G
Sbjct: 136 -----------------------SSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDG 172
Query: 378 SKRITCMKVSDMFAAWSDHRPVCRAR-MCDAHLRGPSGIITSPNFPIQYDNNAHCVWIIT 436
++TC+ S A+W P+CRA C +RG SGII+SP+FP +Y NNA C W I
Sbjct: 173 HPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIV 232
Query: 437 ALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWL 496
A P I L F +F +E YD L + +G + ++ L+G ++P I+S + + L
Sbjct: 233 A-EPGDTISLIFTDFQMEEKYDYLEI-----EGSEPPTIW-LSGMNIPPPIISNKNWLRL 285
Query: 497 LFQTDGSGSSLGFKASYE 514
F TD + GF A Y+
Sbjct: 286 HFVTDSNHRYRGFSAPYQ 303
Score = 165 bits (418), Expect = 6e-40
Identities = 98/285 (34%), Positives = 146/285 (51%), Gaps = 13/285 (4%)
Query: 405 CDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGD 464
C L+G +G I SP FP Y N A+C W+I A ++ I++ F+ F LE YD L++ D
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNR-IQIVFQSFALEEEYDYLSLYD 83
Query: 465 GGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDP 524
G LTG +P + ST L +D + S+ GFK YEE++ SCG+P
Sbjct: 84 GHPHPTNFRTR--LTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 141
Query: 525 GIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNN----QWSAKKPGC--VFSC 578
G+P G G+RF GD +++ C + L G +TC N+ W P C +C
Sbjct: 142 GVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDAC 201
Query: 579 FFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGA 638
SG++ SP++P +Y N+ C W I+A P I L F D +E ++D+L I+
Sbjct: 202 GGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEG-- 259
Query: 639 TAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITF 683
+E P + SG +P I S+ + RL F TD + RGF+ +
Sbjct: 260 -SEPPTI-WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
Score = 157 bits (398), Expect = 1e-37
Identities = 88/289 (30%), Positives = 135/289 (46%), Gaps = 8/289 (2%)
Query: 573 GCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFL 632
G +++C +G + SP +P Y N +C W+I+A +RI + F +E ++D+L
Sbjct: 20 GFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYL 79
Query: 633 VIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECP 692
+ DG +G LP +TS+ V L +D + GF + + + + C
Sbjct: 80 SLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 139
Query: 693 DPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKE-GSVVWNSAV--LRCE 749
+PGVP G +G +G I + C G++ G +TC+ + W+ V R E
Sbjct: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYI-LDGHPQLTCIANSVNTASWDFPVPICRAE 198
Query: 750 APCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVR 809
CGG + SG I SP +P Y + C W I A+PG I + F F+ E YD LE+
Sbjct: 199 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 258
Query: 810 DGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYE 858
S P G +P +IS N+L L F TD +H GF Y+
Sbjct: 259 G----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
Score = 133 bits (335), Expect = 3e-30
Identities = 75/218 (34%), Positives = 103/218 (47%), Gaps = 3/218 (1%)
Query: 1442 IAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHI 1501
I CGG L G +G I SP +P YP G C W + I +VF F LE YD+L +
Sbjct: 22 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 81
Query: 1502 YDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDP 1561
YDG + G LP + S+ + L SD +VS GF + Y E SC +P
Sbjct: 82 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 141
Query: 1562 GSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTA--PC 1619
G G G+ +G + Y C GY ++G L+CI W+ P P+C A C
Sbjct: 142 GVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDAC 201
Query: 1620 GGQYVGSDGVVLSPNYPQNYTSGQICLY-FVTVPKDYV 1656
GG GS G++ SP++P Y + C + V P D +
Sbjct: 202 GGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTI 239
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 3696 bits (9584), Expect = 0.0
Identities = 1701/2975 (57%), Positives = 2167/2975 (72%), Gaps = 80/2975 (2%)
Query: 303 YQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLG 362
++VKK I+ KSRG KL P KDNS K S+L + G+ N+CPDPG PE GKR+GSDF LG
Sbjct: 446 HRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLG 505
Query: 363 SSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFP 422
S+VQF+C+E Y LQG+K ITC +++++FAAWSDHRPVC+ + C ++L+GPSG TSPNFP
Sbjct: 506 STVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFP 565
Query: 423 IQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTS 482
QYD+NA CVW+ITA+N +KVI++ FEEFDLE GYDTLT+GDGG+ GD +TVL +LTG+
Sbjct: 566 FQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSF 625
Query: 483 VPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDT 542
VPDLIVS + QMWL QTD S S+GFK +Y+EIE+ SCGDPG P YG REG F + D
Sbjct: 626 VPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDV 685
Query: 543 LKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHL 602
L+FECQ FEL+G+K+I CQ+NNQWSA P C+F C NFT+P G VLSP+YPE YGN+L
Sbjct: 686 LRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNL 745
Query: 603 HCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGH 662
+C+W I++ P SRIHL+FND D+E QFDFL +KDG + E+P+LGTF+G ++PS +TS+ H
Sbjct: 746 NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSH 805
Query: 663 VARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFL 722
+ RLEFQ DHS RGFNIT+ TF HNECPDPG+P+N +RFGD+ QLGSSIS +C+EGF+
Sbjct: 806 ILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFI 865
Query: 723 GTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVI 782
TQG+ETITC+L +G V+W+ + +C APCGGH ++PSG ILSPGWPG+YKD+L+C WVI
Sbjct: 866 KTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVI 925
Query: 783 EAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLF 842
EA+PG+ IKITF+RF+TE+NYD LEV DG +PL+G Y+GTQVPQFL S+SN++YLLF
Sbjct: 926 EAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLF 985
Query: 843 STDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDG 902
+TD S S+ GF++ YE++T+ + CLDPGIPV+G+R+G+DF +G+ V+FSCDSGY LS
Sbjct: 986 TTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHE 1045
Query: 903 EPLECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGV 962
EPL CE N WS LP+C+ALCGG ++G SGTILSPG+P+FYPN+LNCTW ++ +HGKGV
Sbjct: 1046 EPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1105
Query: 963 FFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSM 1022
F FHTFHLE HDYLLITENGSFTQPL +LTGS LP I+AGLYGNF AQ+RFISDFS+
Sbjct: 1106 QFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSI 1165
Query: 1023 SYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGG 1082
SYEGFNITFSEY+LEPCE+P +P Y R G FG+GDTLTFSC GYRLEGT+ I CLGG
Sbjct: 1166 SYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG 1225
Query: 1083 RRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARA 1142
RR+WS+PLPRCVAECG S T +G LLSPN+P+NY NNHECIYSIQ Q GKGI + AR
Sbjct: 1226 GRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISART 1285
Query: 1143 FELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELH 1202
F L++GDVLK+YDG + + LLG F+ + M G+TL+STS+ LWL+F +D E T +GF+L
Sbjct: 1286 FHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLV 1345
Query: 1203 FSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDR 1262
++SFEL CEDPG P+FGYK+ D+GHFAGS++ + C+PGY+L GS L C++GERR WD
Sbjct: 1346 YTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY 1405
Query: 1263 PLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEV 1322
PLP+C+AECGG +GE SG++LSPGYP PY++NL C+W IE + G + L FL FDTE
Sbjct: 1406 PLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS 1465
Query: 1323 HDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTA 1382
HD+LR+WDGP E+ +LLKE+SG +P+ +HST N V +QF TDF+ SK GFAIQFS S A
Sbjct: 1466 HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1525
Query: 1383 TSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCI 1442
T+C DPG+P NG+R+GD E GD+ VFQCDPGY LQG I+C+++ENR+FWQPSPP CI
Sbjct: 1526 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI 1585
Query: 1443 APCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIY 1502
APCGG+LTG SG ILSPN+P PYP ++CDW +TV+ DYVI+L F F++EP YDFL+IY
Sbjct: 1586 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1645
Query: 1503 DGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPG 1562
DG DS SPLIGSF S+LP RIESSSN++ LAFRSD SVS GF ++Y RESCFDPG
Sbjct: 1646 DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPG 1705
Query: 1563 SIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQ 1622
+I NGTR+G D KLGS+VTYYC GY ++G STL+CI+G DG+P WN P C APCG +
Sbjct: 1706 NIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSR 1765
Query: 1623 YVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHS 1682
GS+G VLSPNYP+NY+ G C+Y + VPK++VVFGQF FF T+L+DVVEV+DG +Q S
Sbjct: 1766 STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQS 1825
Query: 1683 RLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPEPR 1742
LLSSLSGSH+GESLPL++ NQ+ I+F++ G A+GFHFVYQAVPRTS+TQCSSVPEPR
Sbjct: 1826 SLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPR 1885
Query: 1743 YGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTE 1802
+G+R+G++F+VG+ V F+CN GY L GS I C VP +LAQWN S PTC+VPCGG LT+
Sbjct: 1886 FGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTK 1945
Query: 1803 RRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTM 1862
R+GTILSPG+PEPY N+LNCVWKI VPEGAGIQ+QVVSF TE NWDSL+ +DG DN
Sbjct: 1946 RKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPR 2005
Query: 1863 LGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTG 1922
LGS+SGTT+P LLNSTSN LYL+F SDISVSAAGFHLEY +GL SCPEP PS+G+K G
Sbjct: 2006 LGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG 2065
Query: 1923 ERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVILSP 1982
+RY+V DVVSFQC+ GY+LQGH+HI+CMPG VRRWNYP P+C+AQCGG + + GVILSP
Sbjct: 2066 DRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSP 2125
Query: 1983 GFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSE 2042
GFPGNYPS++DC+W I LP+GFG H+QF+NFSTE HDY+E+R+G ETS ++GR SG +
Sbjct: 2126 GFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ 2185
Query: 2043 LPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSFLRGFDLSELERTNSTPP 2102
+PSSL ST+HET++YFHSD+SQN+ GF + YQ
Sbjct: 2186 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQ---------------------------- 2217
Query: 2103 VAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLT 2162
AY+LQ CPDP PF NG V G + VGQ+++FEC PGY L G+ LT
Sbjct: 2218 --------------AYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALT 2263
Query: 2163 CQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRL 2222
C HG +RNW+HPLP+CE CGGNIT+ NGT+YSPG+P Y + QDC WL+ VP G+G+ +
Sbjct: 2264 CLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYI 2323
Query: 2223 NLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIF 2282
N ++LQTEP DFIT+WDGP Q +P++G F+ + A ++V S+SNQ+L+KFH D T G F
Sbjct: 2324 NFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFF 2383
Query: 2283 AIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYL 2342
+++ AY L C PP +PNAE++TE++EF IGDI+RY+CLPGFTLVGN ILTC+LG L
Sbjct: 2384 VLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERL 2443
Query: 2343 QFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYF 2402
Q +G PP+C+V CP NEL DSTGVILS YP SYP Q C+W + VE YNI++ VE+F
Sbjct: 2444 QMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFF 2503
Query: 2403 LSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIR 2462
+EK++D +++DGP+ QSP+L +LSG+YS+ +TS+ + V+L+WS+DH N+KGF+IR
Sbjct: 2504 QTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIR 2563
Query: 2463 YSAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEA 2522
Y A YCS P +P HG+I+ QT Q + + C+ G+RLVG S A+C + GYH W
Sbjct: 2564 YIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAP 2623
Query: 2523 IPLCQALSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNR 2582
+P CQA+SCG+P+AP NG + +Y VGT+ Y C++GY L + TA C G WSN
Sbjct: 2624 VPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNH 2683
Query: 2583 NVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANG 2642
N P+CV VTCP ++S +EHGRWR++ + Y+++ +++ CDPGY+ G I C NG
Sbjct: 2684 NKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNG 2743
Query: 2643 KWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANG 2702
WS + P C+IISCGELP PPNG++IGT + YG+TAIF+C+ G+ LVGS VREC+++G
Sbjct: 2744 TWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSG 2803
Query: 2703 LWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHW 2762
LWS SE RCLAGHCG PE IVNG + GENY YR +VVYQCN GFRLIG SVRICQQDH+W
Sbjct: 2804 LWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNW 2863
Query: 2763 SGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTG 2822
SG+ P CV VSCGHPGSP + + SG+ + VV +SC + G + C + W+
Sbjct: 2864 SGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSH 2923
Query: 2823 SLPHCSGTSVGVCGDPGIPAHGIRLG----DSFDPGTVMRFSCEAGHVLRGSSERTCQAN 2878
P C V C DPGIPA+ R +F GTV+ + C G+ L GSS CQ N
Sbjct: 2924 PPPMC---KVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPN 2980
Query: 2879 GSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNG 2938
G W PEC +I CG+PG P NA V+ + F S++ Y C G SR C +NG
Sbjct: 2981 GQWDKPLPECIMIDCGHPGVPPNA-VLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG 3039
Query: 2939 TWTGSDPEC---LVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCT 2995
W+GS P C CGDPG P +G R ++FR TV Y C GY++ H +C
Sbjct: 3040 HWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYIL--HGSEERTCL 3097
Query: 2996 KDRTWNGTKPVCKALMCKPPPLIPNGKVVGSD-FMWGSSVTYACLEGYQLSLPAVFTCEG 3054
+ +W G +P CKA+ C P NGKV D + SSV Y+C+EGY LS P+V C
Sbjct: 3098 ANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTA 3157
Query: 3055 NGSWTGELPQCFPVFCGDPGVPSRGRREDRGFSYRSSVSFSCHP--PLVLVGSPRRFCQS 3112
NG+W+G LP C + CGDPG+P+ G R + +VS+ C P + L GS R C
Sbjct: 3158 NGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTI 3217
Query: 3113 DGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTC 3172
+GTWSG P+C TC P G + + G ++ + C GY L TC
Sbjct: 3218 NGTWSGVMPTC---RAVTCPTPPQISNG-RLEGTNFDWGFSISYICSPGYELSFPAVLTC 3273
Query: 3173 LPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFS-----LKGGS 3227
+ N TWSG P C+P C P P G + IY + FS + GS
Sbjct: 3274 VGNGTWSGEVPQCLPKFCGDPGIPAQGK-------REGKSFIYQSEVSFSCNFPFILVGS 3326
Query: 3228 EHRTCKADGSWTGKPPICLEVRPSGRPINTAREPP 3262
R C+ADG+W+G P C+E P T+ E P
Sbjct: 3327 STRICQADGTWSGSSPHCIE------PTQTSCENP 3355
Score = 2254 bits (5841), Expect = 0.0
Identities = 1256/3413 (36%), Positives = 1815/3413 (53%), Gaps = 249/3413 (7%)
Query: 136 SHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
S+ C +PG NG + GS F+LG V++SC+ + L+G +TC +E A W P
Sbjct: 483 SNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 542
Query: 196 CRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILA-ELGDTIALVFIDFQLEDGYD 254
C+ CG L+G SG +SP+FP +Y +NA C W I A I + F +F LE GYD
Sbjct: 543 CKVK-TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 601
Query: 255 FLEV-----TGTEGSSLW-FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQ 308
L + G + L TG+ +P ++S + + LH +D + GF Y K+
Sbjct: 602 TLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY---KE 658
Query: 309 IELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFT 368
IE +S C DPG P G R G F ++F
Sbjct: 659 IEKES-----------------------------CGDPGTPLYGIREGDGFSNRDVLRFE 689
Query: 369 CNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNN 428
C G++L G K I C + + WS + P+C C ++ P G + SP++P Y NN
Sbjct: 690 CQFGFELIGEKSIVCQENNQ----WSANIPIC-IFPCLSNFTAPMGTVLSPDYPEGYGNN 744
Query: 429 AHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIV 488
+C+W I + +P I L+F +FDLE +D L V DG D + +L TG VP +
Sbjct: 745 LNCIWTIIS-DPGSRIHLSFNDFDLESQFDFLAVKDG--DSPESPILGTFTGAEVPSHLT 801
Query: 489 STNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQ 548
S +H + L FQ D S S GF +Y C DPGIP RR G F G ++ C+
Sbjct: 802 SNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICE 861
Query: 549 PAF-ELVGQKAITC---QKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHC 604
F + G + ITC WS P C C +F++PSGV+LSP +P Y + L+C
Sbjct: 862 EGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNC 921
Query: 605 VWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVA 664
W+I A P I + F E +D L + DG +P+LG+++G Q+P + SS +
Sbjct: 922 EWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFI 981
Query: 665 RLEFQTDHSTGKRGFNITFTTFRHN--ECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFL 722
L F TD+S GF I + + N C DPG+PV+G+R+G +GS++SF CD G+
Sbjct: 982 YLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYR 1041
Query: 723 GTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVI 782
+ E + C E + W+ + C+A CGG + PSGTILSPG+P FY ++L+C W +
Sbjct: 1042 LSH-EEPLLC---EKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTV 1097
Query: 783 EAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNY----L 838
+ G ++ F F E ++D L + + +++ PL + G+ +P I+ Y
Sbjct: 1098 DVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLT-GSDLPP-TINAGLYGNFRA 1155
Query: 839 YLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYT 898
L F +D S S GF + + L+ C DPGIP G R G +F +G +TFSC SGY
Sbjct: 1156 QLRFISDFSISYEGFNITFSEYNLEP--CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYR 1213
Query: 899 LSDGEPLECEPNFQ--WSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIET 956
L + C + WS LP C A CG + G +LSP +P Y NN C + I+
Sbjct: 1214 LEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQV 1273
Query: 957 SHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQ--- 1013
GKG+ + TFHL G + T L TG+ + GL + T+
Sbjct: 1274 QAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASM-----RGLTLSSTSNQLW 1328
Query: 1014 VRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQ-FGVGDTLTFSCFPGYRLE 1072
+ F SD + EGF + ++ ++L CE+P +P + + Q G T+ + C PGY L
Sbjct: 1329 LEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLH 1388
Query: 1073 GTARITCLGGRRRLWSSPLPRCVAECGNSVTG-TQGTLLSPNFPVNYNNNHECIYSIQTQ 1131
G++ + C+ G RR W PLP C+AECG G + G +LSP +P Y+NN C++ I+
Sbjct: 1389 GSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVD 1448
Query: 1132 PGKGIQLKARAFELSEG-DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFIT 1190
PG + L+ AF+ D+L+V+DG + LL S S ++ ++ST + + + F T
Sbjct: 1449 PGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGS-LIPEGIHSTLNIVTIQFDT 1507
Query: 1191 DAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEEL 1250
D + GF + FSS C DPG P G + + +G G +V F CDPGY L+G E +
Sbjct: 1508 DFYISKSGFAIQFSSSVATACRDPGVPMNGTR-NGDGREPGDTVVFQCDPGYELQGEERI 1566
Query: 1251 LCLSGERRT-WDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCT 1309
C+ E R W P C+A CGG + G SG +LSP +P PY H+ +C WTI A
Sbjct: 1567 TCIQVENRYFWQPSPPVCIAPCGGNLTGS-SGFILSPNFPHPYPHSRDCDWTITVNADYV 1625
Query: 1310 IGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTS 1369
I L F+ F E +D L I+DGP + L+ LP+ + S+ N++ L F +D S
Sbjct: 1626 ISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVS 1685
Query: 1370 KQGFAIQFSVSTATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIE 1429
GF +++ SC DPG NG+R G ++ G + + CD GY LQG + ++C+ +
Sbjct: 1686 YTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGD 1745
Query: 1430 N-RFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFN 1488
+ R W + P+C APCG TG G +LSPNYP+ Y G C + + V ++V+ F
Sbjct: 1746 DGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFV 1805
Query: 1489 IFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIE-SSSNSLFLAFRSDASVSNAGFV 1547
F +D + +YDG S L+ S GS + SS N + + F S ++ GF
Sbjct: 1806 FFQTSL-HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFH 1864
Query: 1548 IDYTENPRESCFDPGSIKN---GTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDG 1604
Y PR S S+ G R+G++ +GSSV + C+ GY + G+ + C P+
Sbjct: 1865 FVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNS 1924
Query: 1605 KPVWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFF 1664
WN+ P C PCGG G +LSP YP+ Y + C++ +TVP+ + Q F
Sbjct: 1925 LAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSF 1984
Query: 1665 HTALN-DVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFV 1723
T N D ++ +DG ++ L S SG+ T L +TSN + + F + A GFH
Sbjct: 1985 ATEHNWDSLDFYDGGDNNAPRLGSYSGT-TIPHLLNSTSNNLYLNFQSDISVSAAGFHLE 2043
Query: 1724 YQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALA 1783
Y A+ S C P G ++G + VG +V F+C+ GY+LQG I C+P G +
Sbjct: 2044 YTAIGLDS---CPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMP--GPVR 2098
Query: 1784 QWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVT 1843
+WN P C+ CGG +++ G ILSPGFP Y +SL+C W I +P G G+ +Q V+F T
Sbjct: 2099 RWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFST 2158
Query: 1844 EQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 1903
E D LEV G+ T T++G SG +P+ L ST+++ L+F+SD S + GFH+ Y+
Sbjct: 2159 ETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2218
Query: 1904 VGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPL 1963
L SCP+P NG G + V +SF+C PGY L G++ ++C+ G R WN+P P
Sbjct: 2219 YQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2278
Query: 1964 CIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIE 2023
C A CGG + M G I SPG+P YP+ DC W + +P G G +I F TEP +D+I
Sbjct: 2279 CEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFIT 2338
Query: 2024 IRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQIS 2083
+ +GP + S +G+FSG+ S+ STS++ + FHSD + + GF + L+Y
Sbjct: 2339 VWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS--GFFV----LSY----- 2387
Query: 2084 SFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANG--IVRGAGYNV 2141
AY+L+ C P P N + + +
Sbjct: 2388 --------------------------------HAYQLRVCQPPPPVPNAEILTEDDEFEI 2415
Query: 2142 GQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNIT--SSNGTVYSPGFP 2199
G + ++CLPG+ L G+ +LTC+ G D P C+V C N S G + SPG+P
Sbjct: 2416 GDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYP 2475
Query: 2200 SPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKK 2259
Y + Q C W I+V G+ + + + QTE D + ++DGP +P L + +
Sbjct: 2476 DSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSA 2535
Query: 2260 -TVQSSSNQVLLKFHRDAATGGI-FAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDI 2317
+ S+ ++V L++ D F I + A+ C P P+ ++++ + +
Sbjct: 2536 FNITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCSTPESPPHGYIISQTGG-QLNSV 2591
Query: 2318 VRYRCLPGFTLVGNEILTCKLGTY--LQFEGPPPICE-VHCPTNELLTDSTGVILSQSYP 2374
VR+ C GF LVG C+ +Y ++ P P C+ + C + T+ G++ +
Sbjct: 2592 VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNG-GILTT---- 2646
Query: 2375 GSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAP 2434
DY + V YF ++ LS
Sbjct: 2647 -----------------DYLVGTRVTYFCNDGY------------------RLSSKELTT 2671
Query: 2435 LIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAP-LHGFILGQTSTQPGGSIH- 2492
+ S WS+ + P C + P ++ FIL + H
Sbjct: 2672 AVCQSDGT-----WSNHN-----------KTPRCVVVTCPSINSFILEHGRWRIVNGSHY 2715
Query: 2493 -------FGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGK 2545
F C+ GY +G + C P G W P CQ +SCG P NG G
Sbjct: 2716 EYKTKVVFSCDPGYHGLGPASIECL--PNGTWSWRNERPYCQIISCGELPTPPNGNKIGT 2773
Query: 2546 EYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTC--PDVSSISVEH 2603
+ + G+ A+++C G+ L A ECL +GLWS +C+ C P++ + +
Sbjct: 2774 QTSYGSTAIFTCDLGFMLVGSA--VRECLSSGLWSESET--RCLAGHCGIPEL----IVN 2825
Query: 2604 GRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPI 2663
G+ + Y ++ ++ C+PG+ G V CQ + WS P+C +SCG
Sbjct: 2826 GQ---VIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWS--GQLPSCVPVSCGHPGS 2880
Query: 2664 PPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIV 2723
P G G + FSCN GY + G +C AN WS C +C P
Sbjct: 2881 PIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPA 2940
Query: 2724 NGH----INGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGS 2779
N I N++Y V Y CN G+ L G SV ICQ + W P C+++ CGHPG
Sbjct: 2941 NSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGV 3000
Query: 2780 PPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPG 2839
PP++ +SG+ YT G+ V YSC GKR+L+G S+R C L+GHW+GS PHCSG + G CGDPG
Sbjct: 3001 PPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPG 3060
Query: 2840 IPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTP 2899
P HG R +F + +R++C+ G++L GS ERTC ANGSW+G QPEC + CGNPGT
Sbjct: 3061 TPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTT 3120
Query: 2900 SNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPA 2959
+N +V DG FSSS++Y C EGY +G R C+ NGTW+G+ P C +I+CGDPGIPA
Sbjct: 3121 ANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPA 3180
Query: 2960 NGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIP 3019
NGLR G+D+ + V+Y C PGY ME + + +CT + TW+G P C+A+ C PP I
Sbjct: 3181 NGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQIS 3240
Query: 3020 NGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRG 3079
NG++ G++F WG S++Y C GY+LS PAV TC GNG+W+GE+PQC P FCGDPG+P++G
Sbjct: 3241 NGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQG 3300
Query: 3080 RREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQF 3139
+RE + F Y+S VSFSC+ P +LVGS R CQ+DGTWSG+ P CI+PT T+C +PGVP+
Sbjct: 3301 KREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRH 3360
Query: 3140 GIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHA 3199
G QNN+ G+QVGS V F C+KG+LLQGSTTRTCLP+LTWSG P+C+PH C+QPETP HA
Sbjct: 3361 GSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHA 3420
Query: 3200 NVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRPI---- 3255
NV +DLPS GYTLIY+CQ GF L GG+EHR C++D +WTGK PIC +G I
Sbjct: 3421 NVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC----EAGSKILVKD 3476
Query: 3256 -NTAREPPLTQALIPGDVFAKNSLWKGAYEYQGKKQPAMLRVTGFQVANSKVNATMIDHS 3314
A P + +P DVFA+N +WKG+Y ++G+KQP L VT F + +VNAT + +S
Sbjct: 3477 PRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNAT-LSNS 3535
Query: 3315 GVELHLAGTYKKEDFHLLLQVYQITGPVEIFMNKFKDDHWALDGHVSSESSGATFIYQGS 3374
+EL L+G YK ++ L+L++Y I P + K K+++WA+DG VS+E GAT+++QG
Sbjct: 3536 NMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGF 3595
Query: 3375 VKGQGFGQFGFQRLDLRLLESDPESIGRHFASNSSSVAAAILVPFIALIIAGFVLYLYKH 3434
++G+ +GQFG QRL L + E S H +NSSSVA AILVPF ALI AGF YLYK
Sbjct: 3596 IQGKDYGQFGLQRLGLNMSEGSNSSNQPH-GTNSSSVAIAILVPFFALIFAGFGFYLYKQ 3654
Query: 3435 RRRPKVPFNGYAGHENTNVRATFENPMYDRNIQPTDIMASEAEFTVSTVCTAV 3487
R PK + G + HEN N +A FENPMYD N + + A + ++TVCT V
Sbjct: 3655 RTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV 3707
Score = 1561 bits (4043), Expect = 0.0
Identities = 1010/3045 (33%), Positives = 1489/3045 (48%), Gaps = 231/3045 (7%)
Query: 17 HHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHR-IQLVFQSFALEE 75
H P + C L GP+GT SP FP+ Y + A C W ITA ++ IQ+ F+ F LE
Sbjct: 539 HRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEI 598
Query: 76 DFDVLSVFDGPP--QPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEV 133
+D L++ DG P + LTG +P IVS ++ + L L +D +V + GF Y+
Sbjct: 599 GYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKE 658
Query: 134 LPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPL 193
+ +CG+PG GI++G F+ D +R+ C GF L G + C ++ W +
Sbjct: 659 IEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ----WSANI 714
Query: 194 PSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGY 253
P C C G + SP +P Y NN +C WTI+++ G I L F DF LE +
Sbjct: 715 PICIFP--CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQF 772
Query: 254 DFLEVTGTEGSSL----WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQI 309
DFL V + FTGA +P+ + S+ + LRL F +D + RGF+ Y
Sbjct: 773 DFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYN----- 827
Query: 310 ELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTC 369
+ GHN CPDPGIP +R G +F+LGSS+ C
Sbjct: 828 ---------------------------TFGHNECPDPGIPINARRFGDNFQLGSSISVIC 860
Query: 370 NEGY-DLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNN 428
EG+ QG++ ITC+ + D WS P C A C H PSG+I SP +P Y ++
Sbjct: 861 EEGFIKTQGTETITCI-LMDGKVMWSGLIPKCGAP-CGGHFSAPSGVILSPGWPGYYKDS 918
Query: 429 AHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIV 488
+C W+I A P IK+ FE F E YD L V DG +L GT VP +
Sbjct: 919 LNCEWVIEA-EPGHSIKITFERFQTELNYDVLEVHDG--PNLLSPLLGSYNGTQVPQFLF 975
Query: 489 STNHQMWLLFQTDGSGSSLGFKASYEEIEQG--SCGDPGIPAYGRREGSRFHHGDTLKFE 546
S+++ ++LLF TD S S+ GFK YE + SC DPGIP +GRR G F G T+ F
Sbjct: 976 SSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFS 1035
Query: 547 CQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVW 606
C + L ++ + C+KN+ WS P C C + PSG +LSP YPE Y N L+C W
Sbjct: 1036 CDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTW 1095
Query: 607 LILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSS---GHV 663
+ + F+ +E D+L+I + + P L +G+ LP +I +
Sbjct: 1096 TVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQP-LARLTGSDLPPTINAGLYGNFR 1154
Query: 664 ARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLG 723
A+L F +D S GFNITF+ + C DPG+P G R G + +G +++F C G+
Sbjct: 1155 AQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYR- 1213
Query: 724 TQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIE 783
+G+ I C L G VW++ + RC A CG T+ G +LSP +P Y++ C + I+
Sbjct: 1214 LEGTSEIIC-LGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQ 1272
Query: 784 AQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQF-LISTSNYLYLLF 842
Q G I I+ F D L++ DG+ + L+G + G + L STSN L+L F
Sbjct: 1273 VQAGKGINISARTFHLAQG-DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEF 1331
Query: 843 STDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGND-FYVGALVTFSCDSGYTLSD 901
++D +D GFQL Y + L HC DPGIP G + + + G+ + + C+ GYTL
Sbjct: 1332 NSDTEGTDEGFQLVYTSFELS--HCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHG 1389
Query: 902 GEPLECEPNFQ--WSRALPSCEALCGGFIQG-SSGTILSPGFPDFYPNNLNCTWIIETSH 958
L+C + W LPSC A CGG +G SSG ILSPG+P Y NNL C W+IE
Sbjct: 1390 SSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDP 1449
Query: 959 GKGVFFTFHTFHLESGHDYLLITENGSFTQPL-RQLTGSRLPAPISAGLYGNFTAQVRFI 1017
G V F F E+ HD L + + L ++++GS +P I + L ++F
Sbjct: 1450 GNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLN---IVTIQFD 1506
Query: 1018 SDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARI 1077
+DF +S GF I FS C +P VP R G GDT+ F C PGY L+G RI
Sbjct: 1507 TDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERI 1566
Query: 1078 TCLGGRRR-LWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGI 1136
TC+ R W P C+A CG ++TG+ G +LSPNFP Y ++ +C ++I I
Sbjct: 1567 TCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVI 1626
Query: 1137 QLKARAFELSEG-DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENT 1195
L +F + D L +YDG ++++ L+G F S++ + S+S+++ L F +D +
Sbjct: 1627 SLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE-RIESSSNTMHLAFRSDGSVS 1685
Query: 1196 SKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSG 1255
GF L + + C DPG G ++ + + GS+V++ CD GY L+G L C+ G
Sbjct: 1686 YTGFHLEYKAKLRESCFDPGNIMNGTRLGMD-YKLGSTVTYYCDAGYVLQGYSTLTCIMG 1744
Query: 1256 E--RRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLH 1313
+ R W+R LP+C A CG G G VLSP YP Y NC+++I +
Sbjct: 1745 DDGRPGWNRALPSCHAPCGSRSTGS-EGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQ 1803
Query: 1314 FLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLH-STFNSVVLQFSTDFFTSKQG 1372
F+ F T +HDV+ ++DGP + LL LSG + L S+ N + ++F++ + +G
Sbjct: 1804 FVFFQTS-LHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKG 1862
Query: 1373 FAIQFSV---STATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIE 1429
F + +++T C+ P+ G R G+ + G S +F C+PGY L GS I C +
Sbjct: 1863 FHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVP 1922
Query: 1430 NRFF-WQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFN 1488
N W S PTCI PCGG LT G ILSP YPEPY C WK+TV I +
Sbjct: 1923 NSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV 1982
Query: 1489 IFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVI 1548
F E +D L YDG D+ +P +GS+ G+ +P + S+SN+L+L F+SD SVS AGF +
Sbjct: 1983 SFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHL 2042
Query: 1549 DYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVW 1608
+YT +SC +P + +G ++G +G V++ C GY ++G S ++C+ GP + W
Sbjct: 2043 EYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRR--W 2100
Query: 1609 NNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHT-A 1667
N P P+C A CGG GV+LSP +P NY S C + + +P + V QF F T
Sbjct: 2101 NYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET 2160
Query: 1668 LNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAV 1727
++D +EV G S+ S ++ LSG SL +T+++ + F + +GFH VYQA
Sbjct: 2161 IHDYLEVRSGSSETSTVIGRLSGPQIPSSL-FSTTHETSLYFHSDYSQNKQGFHIVYQAY 2219
Query: 1728 PRTSATQCSSVPEPR---YGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQ 1784
Q S P+PR G +G+DF+VG + FEC GY L G+ + CL G
Sbjct: 2220 ------QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLH--GVSRN 2271
Query: 1785 WNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTE 1844
WN P C CGGN+T GTI SPG+P+ Y N +C W + VP G GI I TE
Sbjct: 2272 WNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTE 2331
Query: 1845 QNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 1904
+D + V+DG D +G FSG T + STSNQ+ + F+SD + S F L Y
Sbjct: 2332 PIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGF-FVLSYHAY 2390
Query: 1905 GLSSC-PEPAVPSNGVKT-GERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPP 1962
L C P P VP+ + T + + + D++ +QC PG+ L G+A ++C G + + PP
Sbjct: 2391 QLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPP 2450
Query: 1963 LCIAQCGGTVEEME--GVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHD 2020
+C C ++ GVILSPG+P +YP+ C+W I++ G+ + F TE D
Sbjct: 2451 VCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFD 2510
Query: 2021 YIEIRNGPYETSRMMGRFSGSELPS-SLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYS 2079
+++ +GP S ++ SG + ++ S HE + + +DH N+ GF++ Y S
Sbjct: 2511 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2570
Query: 2080 ---------------HQISSFL-----RGFDLSELERTNSTPPVAASYVWDLD-PGCEAY 2118
Q++S + RGF L + WD P C+A
Sbjct: 2571 TPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI 2630
Query: 2119 ELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWD--HPLP 2176
C P+ NG + Y VG VT+ C GY+L+ + T ++ W + P
Sbjct: 2631 ---SCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTP 2687
Query: 2177 KCEVPCGGNITS----------SNGTVY----------SPGFPSPYSSSQDCV----WLI 2212
+C V +I S NG+ Y PG+ +S +C+ W
Sbjct: 2688 RCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSW 2747
Query: 2213 TVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKF 2272
+ ++ L T P+G+ I G Q + +FT + V S+
Sbjct: 2748 RNERPYCQIISCGELPTPPNGNKI----GTQTSYGSTAIFTCDLGFMLVGSAV------- 2796
Query: 2273 HRDAATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNE 2332
R+ + G+++ + + C P ++ N +V+ EN + D V Y+C PGF L+G+
Sbjct: 2797 -RECLSSGLWSESETRCLAGHCGIPELIVNGQVIGEN--YGYRDTVVYQCNPGFRLIGSS 2853
Query: 2333 ILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPD 2392
+ C+ + G P C V +S +PGS +T
Sbjct: 2854 VRICQQDH--NWSGQLPSC---------------VPVSCGHPGSPIYGRTSGNGFNFNDV 2896
Query: 2393 YNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALS------------------GNYSAP 2434
S + Y + + + S P+ K ++ GN++
Sbjct: 2897 VTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYG 2956
Query: 2435 LIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSL-----PRAPLHGFILGQTSTQPGG 2489
+V N Y + S + + P C + P P + + G+ T G
Sbjct: 2957 TVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTF-GS 3015
Query: 2490 SIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQ---ALSCGLPEAPKNGMVFGKE 2546
++H+ C L+G S C + WS + P C +CG P P +G
Sbjct: 3016 TVHYSCTGKRSLLGQSSRTCQLNGH----WSGSQPHCSGDATGTCGDPGTPGHGSRQESN 3071
Query: 2547 YTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRW 2606
+ + Y+C GY L E T CL G W+ R P+C V C + + + +G+
Sbjct: 3072 FRTKSTVRYACDTGYILHGSEERT--CLANGSWTGRQ--PECKAVQCGNPGTTA--NGKV 3125
Query: 2607 RLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPN 2666
I T F + ++ C GY +G V +C ANG WS + P C IISCG+ IP N
Sbjct: 3126 FRIDGT--TFSSSVIYSCMEGYILSGPSVRQCTANGTWS--GTLPNCTIISCGDPGIPAN 3181
Query: 2667 GHRIGTLSVYGATAIFSCNSGYT--LVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVN 2724
G R G V G + C GYT L GSR+R C NG WSG C A C TP I N
Sbjct: 3182 GLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISN 3241
Query: 2725 GHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQ 2784
G + G N+ + S+ Y C+ G+ L +V C + WSG+ P C+ CG PG P +
Sbjct: 3242 GRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGK 3301
Query: 2785 MSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHG 2844
G S+ + V +SC LVG+STR+C DG W+GS PHC + C +PG+P HG
Sbjct: 3302 REGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHG 3361
Query: 2845 IRLGD-SFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNAR 2903
+ F G+V++F C+ GH+L+GS+ RTC + +WSG QPEC SC P TP++A
Sbjct: 3362 SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHAN 3421
Query: 2904 VVFSDGLVFSSSIVYECREGYY-ATGLLSRHCSVNGTWTGSDPEC 2947
VV D +++Y C+ G++ A G R C + TWTG P C
Sbjct: 3422 VVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC 3466
Score = 939 bits (2428), Expect = 0.0
Identities = 767/2610 (29%), Positives = 1125/2610 (43%), Gaps = 355/2610 (13%)
Query: 734 LKEGSVVWNSAVLRCEA-------PCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQP 786
+K G WN L + CGG L +GTI SPG+P Y + +C WVI A+
Sbjct: 40 IKSGFTFWNLVFLLTVSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEE 99
Query: 787 GYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDK 846
I+I F F E YD L + DG + G +P + ST + L ++D
Sbjct: 100 RNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDF 159
Query: 847 SHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLE 906
+ S GF++ YE LQS C +PG+P G +G F VG + +SC +GY L L
Sbjct: 160 AVSAHGFKVYYE--ELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLT 217
Query: 907 CEPN----FQWSRALPSCEA--LCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGK 960
C N W +P C A CGG ++GSSG I SP FP+ Y NN +CTW I G
Sbjct: 218 CIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGD 277
Query: 961 GVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDF 1020
+ F F +E +DYL I GS P L+G +P PI + ++ F++D
Sbjct: 278 TISLIFTDFQMEEKYDYLEI--EGS-EPPTIWLSGMNIPPPI---ISNKNWLRLHFVTDS 331
Query: 1021 SMSYEGFNI----------TFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYR 1070
+ Y GF+ T S +LE A ++ ++T
Sbjct: 332 NHRYRGFSAPYQGSSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLS 391
Query: 1071 LEGTARITCLGGRRRLWSSPLPRCVAECGNS--VTGTQGTLLSPNFPVNYNNNHECIYSI 1128
E ++T L +S L ++ G S TQ T P E + +
Sbjct: 392 EEQRVQVTSLR------NSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKE-LAVV 444
Query: 1129 QTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDF 1188
+ K I K+R F K++ G +NS + FS G+ T+S+L
Sbjct: 445 THRVKKAIDFKSRGF--------KLFPGKDNSNK----FSILNEGGI---KTASNL---- 485
Query: 1189 ITDAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSE 1248
C DPG P+ G ++ + GS+V FSCD Y L+G++
Sbjct: 486 ----------------------CPDPGEPENGKRIGSD-FSLGSTVQFSCDEDYVLQGAK 522
Query: 1249 ELLC--LSGERRTWDRPLPTC-VAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEA- 1304
+ C ++ W P C V CG ++G SG SP +P Y+ N C+W I A
Sbjct: 523 SITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGP-SGTFTSPNFPFQYDSNAQCVWVITAV 581
Query: 1305 EAGCTIGLHFLVFDTEEVHDVLRIWDGPV--ESGVLLKELSGPALPKDLHSTFNSVVLQF 1362
I ++F FD E +D L I DG + +L+ L+G +P + S + + L
Sbjct: 582 NTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHL 641
Query: 1363 STDFFTSKQGFAIQFSVSTATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAE 1422
TD GF + + SC DPG P G R GD + D F+C G+ L G
Sbjct: 642 QTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKS 701
Query: 1423 ISCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYV 1482
I C + W + P CI PC + T P G +LSP+YPE Y C W + P
Sbjct: 702 IVC---QENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSR 758
Query: 1483 IALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVS 1542
I L FN F+LE +DFL + DG SP++G+F G+++P + S+S+ L L F++D S+S
Sbjct: 759 IHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMS 818
Query: 1543 NAGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGY-EVEGTSTLSCILG 1601
GF I Y C DPG N R G + +LGSS++ C G+ + +GT T++CIL
Sbjct: 819 GRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCIL- 877
Query: 1602 PDGKPVWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQF 1661
DGK +W+ P C APCGG + GV+LSP +P Y C + + + + F
Sbjct: 878 MDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITF 937
Query: 1662 AFFHTALN-DVVEVHDGHSQHSRLLSSLSGSHTGESLP---LATSNQVLIKFSAKGLAPA 1717
F T LN DV+EVHDG LLS L GS+ G +P ++SN + + F+
Sbjct: 938 ERFQTELNYDVLEVHDG----PNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSN 993
Query: 1718 RGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLP 1777
GF Y++V + C P +G+R G DFS+G+ V F C+SGY L + C
Sbjct: 994 NGFKIHYESV-TVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLC-- 1050
Query: 1778 VPGALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQ 1837
W+ PTC CGG++ GTILSPG+PE Y NSLNC W + V G G+Q
Sbjct: 1051 --EKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFN 1108
Query: 1838 VVSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNS---TSNQLYLHFYSDISVSA 1894
+F E + D L + + T L +G+ +P +N+ + + L F SD S+S
Sbjct: 1109 FHTFHLEDHHDYLLITENGSFT-QPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISY 1167
Query: 1895 AGFHLEYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTV 1954
GF++ + L C +P +P G + G + + D ++F C GY L+G + I C+ G
Sbjct: 1168 EGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGR 1227
Query: 1955 RRWNYPPPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFS 2014
R W+ P P C+A+CG + EG++LSP +P NY +N +C + I + G G +I F
Sbjct: 1228 RVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFH 1287
Query: 2015 TEPNHDYIEIRNGPYETSRMMGRFSGSELPS-SLLSTSHETTVYFHSDHSQNRPGFKLEY 2073
D ++I +G +T+ ++G F+G+ + +L STS++ + F+SD GF+L Y
Sbjct: 1288 LAQG-DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1346
Query: 2074 QDLTYSHQISSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPE-PFANG 2132
++EL C DP P
Sbjct: 1347 ------------------------------------------TSFELSHCEDPGIPQFGY 1364
Query: 2133 IVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNIT-SSNG 2191
+ G+ G ++ + C PGY L G +L C G R WD+PLP C CGG S+G
Sbjct: 1365 KISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSG 1424
Query: 2192 TVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGV 2251
+ SPG+P PY ++ C+W+I V G+ V L TE S D + +WDGP + L
Sbjct: 1425 RILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKE 1484
Query: 2252 FTRSMAKKTVQSSSNQVLLKFHRD-AATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENE 2310
+ S+ + + S+ N V ++F D + FAI FS+ T C P + N +
Sbjct: 1485 ISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGR 1544
Query: 2311 EFNIGDIVRYRCLPGFTLVGNEILTC-KLGTYLQFEGPPPICEVHCPTNELLTDSTGVIL 2369
E GD V ++C PG+ L G E +TC ++ ++ PP+C C N LT S+G IL
Sbjct: 1545 E--PGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGN--LTGSSGFIL 1600
Query: 2370 SQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSG 2429
S ++P YP + C W + V DY ISL F E YD I+DGP SPL+ +
Sbjct: 1601 SPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQD 1660
Query: 2430 NYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPY---CSLPRAPLHGFILGQTSTQ 2486
+ P + SSSN+++L + SD + + GF + Y A C P ++G LG +
Sbjct: 1661 S-KLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGM-DYK 1718
Query: 2487 PGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMV---- 2542
G ++ + C+AGY L G+S C G W+ A+P C A CG G V
Sbjct: 1719 LGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHA-PCGSRSTGSEGTVLSPN 1777
Query: 2543 FGKEYTVGTKAMYSCS---------EGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTC 2593
+ K Y+VG +YS + + Q E D P Q +
Sbjct: 1778 YPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDG--------PTQQSSL-- 1827
Query: 2594 PDVSSISVEHGRWRLIFETQYQFQAQLML---ICDPGYYYTGQRVIRCQANGKWSLGDST 2650
+SS+S H L + Q + I G+++ Q V R +
Sbjct: 1828 --LSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSST--------- 1876
Query: 2651 PTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVREC--MANGL--WSG 2706
C +P P G RIG G++ +F CN GY L GS C + N L W+
Sbjct: 1877 ------QCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWND 1930
Query: 2707 SEVRCLAG-------------HCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSV 2753
S C+ G PEP N N + + AG I + V
Sbjct: 1931 SLPTCIVPCGGILTKRKGTILSPGYPEPYDN------NLNCVWKITVPEGAG---IQVQV 1981
Query: 2754 RICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRM 2813
+H+W G +P SG T + S L S
Sbjct: 1982 VSFATEHNWDSLD----FYDGGDNNAPRLGSYSG---TTIPHLLNSTSNNLYLNFQSDIS 2034
Query: 2814 CGLDGHWTGSLPHCSGTSVGV--CGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSS 2871
G H T++G+ C +P P+ GI++GD + G V+ F C+ G+ L+G S
Sbjct: 2035 VSAAGF------HLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHS 2088
Query: 2872 ERTCQAN--GSWSGSQP----ECG---------VISCGNPGT-PSNARVVFSDGLV---- 2911
TC W+ P +CG ++S G PG PS+ ++ L
Sbjct: 2089 HITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFG 2148
Query: 2912 -------FSSSIVY---ECREGYYAT----GLLSRHCSVNGTWTGSDPECLVI------- 2950
FS+ ++ E R G T G LS + ++ + L
Sbjct: 2149 VHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQN 2208
Query: 2951 --------------NCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTK 2996
+C DP NG +GNDF +T++++C PGY + + S L+C
Sbjct: 2209 KQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGN--SALTCLH 2266
Query: 2997 --DRTWNGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTC-- 3052
R WN P C+AL C NG + GY P C
Sbjct: 2267 GVSRNWNHPLPRCEAL-CGGNITAMNGTIYS--------------PGYPDEYPNFQDCFW 2311
Query: 3053 -----EGNGSW-------TGELPQCFPVFCG-DPGVPSRGRREDRGFSYRSSVSFSCHPP 3099
GNG + T + V+ G D P G + G + SV + +
Sbjct: 2312 LVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIG--QFSGNTALESVYSTSNQI 2369
Query: 3100 LVLVGSPRRFCQSDGTWSG-TQPSCIDPTLTTC-ADPGVPQFGIQNNSQGYQVGSTVLFR 3157
L+ SD T SG S L C P VP I +++G + ++
Sbjct: 2370 LIKF-------HSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQ 2422
Query: 3158 CQKGYLLQGSTTRTCL--PNLTWSGTPPDC 3185
C G+ L G+ TC L G PP C
Sbjct: 2423 CLPGFTLVGNAILTCRLGERLQMDGAPPVC 2452
Score = 929 bits (2402), Expect = 0.0
Identities = 696/2394 (29%), Positives = 1070/2394 (44%), Gaps = 250/2394 (10%)
Query: 16 SHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEE 75
SH + C + GP+GT+ SPG+P YPN NCTWT+ +Q F +F LE+
Sbjct: 1057 SHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLED 1116
Query: 76 DFDVLSVFDGPPQPENLRTRLTGFQLPATI---VSAATTLSLRLISDYAVSAQGFHATYE 132
D L + + + L RLTG LP TI + LR ISD+++S +GF+ T+
Sbjct: 1117 HHDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1175
Query: 133 VLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFP 192
C +PG G + G F +GD + +SC+ G+ LEG + + C G W P
Sbjct: 1176 EYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRR--VWSAP 1233
Query: 193 LPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG 252
LP C A+ CG + GI+ SP++P Y NN +C ++I + G I + F L G
Sbjct: 1234 LPRCVAE--CGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG 1291
Query: 253 YDFLEVTGTEGSSLW----FTGASLPAPVISS-KNWLRLHFTSDGNHRQRGFSAQYQVKK 307
D L++ + + FTGAS+ +SS N L L F SD GF Y
Sbjct: 1292 -DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY---T 1347
Query: 308 QIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRL-GSSVQ 366
EL + C DPGIP+ G ++ GS++
Sbjct: 1348 SFEL-----------------------------SHCEDPGIPQFGYKISDQGHFAGSTII 1378
Query: 367 FTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRG-PSGIITSPNFPIQY 425
+ CN GY L GS + CM + AW P C A C +G SG I SP +P Y
Sbjct: 1379 YGCNPGYTLHGSSLLKCM--TGERRAWDYPLPSCIAE-CGGRFKGESSGRILSPGYPFPY 1435
Query: 426 DNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPD 485
DNN C+W+I ++P ++ L F FD E +D L V DG + D +L ++G+ +P+
Sbjct: 1436 DNNLRCMWMI-EVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDM--LLKEISGSLIPE 1492
Query: 486 LIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKF 545
I ST + + + F TD S GF + +C DPG+P G R G GDT+ F
Sbjct: 1493 GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVF 1552
Query: 546 ECQPAFELVGQKAITC-QKNNQ--WSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHL 602
+C P +EL G++ ITC Q N+ W P C+ C N T SG +LSPN+P Y +
Sbjct: 1553 QCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSR 1612
Query: 603 HCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGH 662
C W I + I LAF +EP +DFL I DG + +P++G+F ++LP I SS +
Sbjct: 1613 DCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSN 1672
Query: 663 VARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFL 722
L F++D S GF++ + C DPG +NG R G +LGS++++ CD G++
Sbjct: 1673 TMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYV 1732
Query: 723 GTQGSETITCVL-KEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWV 781
QG T+TC++ +G WN A+ C APCG T GT+LSP +P Y +C +
Sbjct: 1733 -LQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYS 1791
Query: 782 IEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFL-ISTSNYLYL 840
I + + F F+T + +D +EV DG T + L+ G+ + L +S+ N + +
Sbjct: 1792 IAVPKEFVVFGQFVFFQTSL-HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITI 1850
Query: 841 LFSTDKSHSDIGFQLRYETI-TLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTL 899
F++ + GF Y+ + S C P G+R GN+F VG+ V F C+ GY L
Sbjct: 1851 RFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYIL 1910
Query: 900 SDGEPLECE--PN--FQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIE 955
+ CE PN QW+ +LP+C CGG + GTILSPG+P+ Y NNLNC W I
Sbjct: 1911 HGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKIT 1970
Query: 956 TSHGKGVFFTFHTFHLESGHDYLLITENGSFTQP-LRQLTGSRLPAPI---SAGLYGNFT 1011
G G+ +F E D L + G P L +G+ +P + S LY NF
Sbjct: 1971 VPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQ 2030
Query: 1012 AQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRL 1071
SD S+S GF++ ++ L+ C EP+ P+ I+ G ++ VGD ++F C GY L
Sbjct: 2031 ------SDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSL 2084
Query: 1072 EGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQ 1131
+G + ITC+ G R W+ P+P C+A+CG +++ G +LSP FP NY ++ +C ++I
Sbjct: 2085 QGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLP 2144
Query: 1132 PGKGIQLKARAFELSE-GDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFIT 1190
G G+ L+ F D L+V G++ ++ ++G S ++ +L ST+ L F +
Sbjct: 2145 IGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPS-SLFSTTHETSLYFHS 2203
Query: 1191 DAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEEL 1250
D +GF + + +++L C DP + G+ + ++ G ++SF C PGY+L G+ L
Sbjct: 2204 DYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGND-FTVGQTISFECFPGYTLIGNSAL 2262
Query: 1251 LCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTI 1310
CL G R W+ PLP C A CGG + ++G + SPGYP Y + +C W + G I
Sbjct: 2263 TCLHGVSRNWNHPLPRCEALCGGNITA-MNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGI 2321
Query: 1311 GLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSK 1370
++F V TE ++D + +WDGP ++ + + SG + ++ST N ++++F +DF TS
Sbjct: 2322 YINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS- 2380
Query: 1371 QGFAIQFSVSTATSCNDPGIPQNGS--RSGDSWEAGDSTVFQCDPGYALQGSAEISCVKI 1428
F + + C P N D +E GD +QC PG+ L G+A ++C ++
Sbjct: 2381 GFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTC-RL 2439
Query: 1429 ENRFFWQPSPPTC--IAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALV 1486
R +PP C + P +GVILSP YP+ YP + C W ++V Y I +
Sbjct: 2440 GERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMF 2499
Query: 1487 FNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPG-RIESSSNSLFLAFRSDASVSNAG 1545
F E +D L +YDG + SP++ S G I S+ + +FL + +D + G
Sbjct: 2500 VEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKG 2559
Query: 1546 FVIDYTENPRESCFDPGSIKNGTRVG-SDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDG 1604
F I Y C P S +G + + +L S V + C G+ + G S+ C G
Sbjct: 2560 FRIRYI---AFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYG 2616
Query: 1605 KPVWNNPRPVCTA-PCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAF 1663
W+ P P C A CG ++G +L+ + Y V Y +
Sbjct: 2617 YHAWDAPVPACQAISCGIPKAPTNGGILTTD------------YLVGTRVTYFCNDGYRL 2664
Query: 1664 FHTALNDVVEVHDG-HSQHSRL----------LSSLSGSH------TGESLPLATSNQVL 1706
L V DG S H++ ++S H G T
Sbjct: 2665 SSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFS 2724
Query: 1707 IKFSAKGLAPA------RGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFE 1760
GL PA G P C +P P G ++G+ S G+ F
Sbjct: 2725 CDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFT 2784
Query: 1761 CNSGYALQGSPEIECLPVPGALAQWNVSAPTCVV-PCGGNLTERRGTILSP--GFPEPYL 1817
C+ G+ L GS ECL + W+ S C+ CG G ++ G+ + +
Sbjct: 2785 CDLGFMLVGSAVRECL----SSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVV 2840
Query: 1818 NSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDS-----LEVFDG-ADNTVTMLGSFSGTTV 1871
N ++++ G+ ++I + NW + V G + + S +G
Sbjct: 2841 YQCNPGFRLI---GSSVRI----CQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNF 2893
Query: 1872 PALLNSTSNQLYLHFYSDISVSAAGFHLEY--KTVGLSSCPEPAVPSNGVKTGE----RY 1925
++ + N YL + A + + +C +P +P+N + + +
Sbjct: 2894 NDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNF 2953
Query: 1926 LVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVILSPGFP 1985
VV + C PGY L G + + C P +W+ P P CI ++ G P
Sbjct: 2954 TYGTVVFYDCNPGYFLFGSSVLICQPN--GQWDKPLPECI-------------MIDCGHP 2998
Query: 1986 GNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELPS 2045
G P+ + K FG+ + + + T ++ G +SGS+
Sbjct: 2999 GVPPNAVLSGEKYT----FGSTVHYSCTGKR------SLLGQSSRTCQLNGHWSGSQPHC 3048
Query: 2046 SLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSFLRGFDLSELERTNSTPPVAA 2105
S +T S+ F+ + + Y+ L G + ERT A
Sbjct: 3049 SGDATGTCGDPGTPGHGSRQESNFRTK-STVRYACDTGYILHGSE----ERT-----CLA 3098
Query: 2106 SYVW-DLDPGCEAYELQECPDPEPFANG-IVRGAGYNVGQSVTFECLPGYQLTGHPVLTC 2163
+ W P C+A +C +P ANG + R G SV + C+ GY L+G V C
Sbjct: 3099 NGSWTGRQPECKAV---QCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQC 3155
Query: 2164 QHGTNRNWDHPLPKCE-VPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRL 2222
N W LP C + CG +NG Y + + S C G+ + L
Sbjct: 3156 T--ANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMC------QPGYTMEL 3207
Query: 2223 NLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIF 2282
N S ++T W G T +
Sbjct: 3208 NGSRIRTCTING---TWSGVMPTCRAV--------------------------------- 3231
Query: 2283 AIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTC 2336
CP P + N + E F+ G + Y C PG+ L +LTC
Sbjct: 3232 ----------TCPTPPQISNGRL--EGTNFDWGFSISYICSPGYELSFPAVLTC 3273
Score = 398 bits (1022), Expect = e-110
Identities = 179/279 (64%), Positives = 220/279 (78%)
Query: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG 85
C L G NGT+ESPGFPYGYPN ANCTW I AEE++RIQ+VFQSFALEE++D LS++DG
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
Query: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRL 145
P P N RTRLTGF LP + S + SLRL SD+AVSA GF YE L S +CGNPG
Sbjct: 125 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVP 184
Query: 146 PNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGT 205
P G+ G+ F++GDK+RYSC G+ L+GH LTC A S N+A+WDFP+P CRA+DACGGT
Sbjct: 185 PKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGT 244
Query: 206 LRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSS 265
+RG SGIISSP FP+EYHNNADCTWTI+AE GDTI+L+F DFQ+E+ YD+LE+ G+E +
Sbjct: 245 MRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPT 304
Query: 266 LWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQ 304
+W +G ++P P+IS+KNWLRLHF +D NHR RGFSA YQ
Sbjct: 305 IWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
Score = 184 bits (466), Expect = 2e-45
Identities = 113/318 (35%), Positives = 160/318 (50%), Gaps = 44/318 (13%)
Query: 202 CGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGT 261
CGGTL+G +G I SP FP Y N A+CTW I+AE + I +VF F LE+ YD+L +
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
Query: 262 EGSSLWF----TGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVK 317
F TG LP PV S+K+ L TSD GF Y+ EL+S
Sbjct: 125 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYE-----ELQS---- 175
Query: 318 LMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQG 377
+ C +PG+P +G G+ F +G ++++C GY L G
Sbjct: 176 -----------------------SSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDG 212
Query: 378 SKRITCMKVSDMFAAWSDHRPVCRAR-MCDAHLRGPSGIITSPNFPIQYDNNAHCVWIIT 436
++TC+ S A+W P+CRA C +RG SGII+SP+FP +Y NNA C W I
Sbjct: 213 HPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIV 272
Query: 437 ALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWL 496
A P I L F +F +E YD L + +G + ++ L+G ++P I+S + + L
Sbjct: 273 A-EPGDTISLIFTDFQMEEKYDYLEI-----EGSEPPTIW-LSGMNIPPPIISNKNWLRL 325
Query: 497 LFQTDGSGSSLGFKASYE 514
F TD + GF A Y+
Sbjct: 326 HFVTDSNHRYRGFSAPYQ 343
Score = 165 bits (418), Expect = 6e-40
Identities = 98/285 (34%), Positives = 146/285 (51%), Gaps = 13/285 (4%)
Query: 405 CDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGD 464
C L+G +G I SP FP Y N A+C W+I A ++ I++ F+ F LE YD L++ D
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNR-IQIVFQSFALEEEYDYLSLYD 123
Query: 465 GGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDP 524
G LTG +P + ST L +D + S+ GFK YEE++ SCG+P
Sbjct: 124 GHPHPTNFRTR--LTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 181
Query: 525 GIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNN----QWSAKKPGC--VFSC 578
G+P G G+RF GD +++ C + L G +TC N+ W P C +C
Sbjct: 182 GVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDAC 241
Query: 579 FFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGA 638
SG++ SP++P +Y N+ C W I+A P I L F D +E ++D+L I+
Sbjct: 242 GGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEG-- 299
Query: 639 TAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITF 683
+E P + SG +P I S+ + RL F TD + RGF+ +
Sbjct: 300 -SEPPTI-WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 342
Score = 157 bits (398), Expect = 1e-37
Identities = 88/289 (30%), Positives = 135/289 (46%), Gaps = 8/289 (2%)
Query: 573 GCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFL 632
G +++C +G + SP +P Y N +C W+I+A +RI + F +E ++D+L
Sbjct: 60 GFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYL 119
Query: 633 VIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECP 692
+ DG +G LP +TS+ V L +D + GF + + + + C
Sbjct: 120 SLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
Query: 693 DPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKE-GSVVWNSAV--LRCE 749
+PGVP G +G +G I + C G++ G +TC+ + W+ V R E
Sbjct: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYI-LDGHPQLTCIANSVNTASWDFPVPICRAE 238
Query: 750 APCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVR 809
CGG + SG I SP +P Y + C W I A+PG I + F F+ E YD LE+
Sbjct: 239 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 298
Query: 810 DGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYE 858
S P G +P +IS N+L L F TD +H GF Y+
Sbjct: 299 G----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 436 bits (1120), Expect = e-121
Identities = 339/1216 (27%), Positives = 511/1216 (42%), Gaps = 131/1216 (10%)
Query: 2113 PGCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWD 2172
P CE C P P NG + G +VT++C GY L G + C + N
Sbjct: 1683 PHCERIS---CGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGV 1739
Query: 2173 HP----LPKCEV--PCGGNITSSN--GTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNL 2224
P + +C V C + + N G+ P ++C I
Sbjct: 1740 SPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGH 1799
Query: 2225 SLLQTEPSGDFITIWDGPQQT-APRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFA 2283
S SG+ T+ G + T + + G + K T S L + A +
Sbjct: 1800 S------SGEIYTV--GAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVS----- 1846
Query: 2284 IAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQ 2343
C P I N + E F G V YRC G+TL G++ +C +
Sbjct: 1847 ----------CGKPAIPENGCI--EELAFTFGSKVTYRCNKGYTLAGDKESSCLANS--S 1892
Query: 2344 FEGPPPICE-VHCPTNELLTDSTGVILSQSY--PGSYPQFQTCSWLVRVEPDYNISLTVE 2400
+ PP+CE V C + E + + ++ +Y SY +C ++ I T
Sbjct: 1893 WSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASY----SCDTGYSLQGPSIIECTAS 1948
Query: 2401 YFLSEKQYDEFEIFDGPSGQSPLLK---ALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRK 2457
+F G+ P +K N++ VT + Y D
Sbjct: 1949 GIWDRAPPACHLVF---CGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLA 2005
Query: 2458 GFKIRYSAPYC---SLPRAPLHGFILGQTSTQPGGSIHFG-CNAGYRLVGHSMAICTRHP 2513
K S C S P+ +T+ + G I F C+ GY L +S +C
Sbjct: 2006 DGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQG 2065
Query: 2514 QGYHLWSEAIPLCQALSCGLPEAPKNGM---VFGKEYTVGTKAMYSCSEGYHLQAGAEAT 2570
+ + +P C A C P + + V ++ G+ + C EG+ L A+
Sbjct: 2066 KWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKI- 2124
Query: 2571 AECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYY 2630
EC+ G W+ + QC+PV C + SI + + Y F A + C+ G+Y
Sbjct: 2125 -ECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASG-----SNYSFGAMVAYSCNKGFYI 2178
Query: 2631 TGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLS-VYGATAIFSCNSGYT 2689
G++ C+A G+WS PTC +SCGE P NG T ++ + + CN GY
Sbjct: 2179 KGEKKSTCEATGQWS--SPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYK 2236
Query: 2690 LVGSRVRECMANGLW-SGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRL 2748
VGS V C AN W S S + C+ CG P PI NG + GEN+ V + CN G+ L
Sbjct: 2237 SVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYEL 2296
Query: 2749 IGMSVRICQQDHHWSGKT-PFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLV 2807
+G S CQ+ W+ K+ P C+ C P + + + T VV +SC L
Sbjct: 2297 VGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQ 2356
Query: 2808 GNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDS-FDPGTVMRFSCEAGHV 2866
G S C W S P C + +C P + + G+ + S G+ +++SC G
Sbjct: 2357 GPSVLKCLPSQQWNDSFPVCK---IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFF 2413
Query: 2867 LRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYA 2926
LRG+S CQ +G+WS PEC + C P N ++ GL + S+ +Y C+ G+
Sbjct: 2414 LRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNG-IIDVQGLAYLSTALYTCKPGFEL 2472
Query: 2927 TGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMES 2986
G + C NG W G P C I C P NG D Y +TVTY C G+ +E
Sbjct: 2473 VGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEG 2532
Query: 2987 HRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSL 3046
S L+C + W+ P C A+ C P I NG V G+D+ +G+ + Y+C G+Q++
Sbjct: 2533 P--SALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAG 2590
Query: 3047 PAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRG----RREDRG----------------- 3085
A+ TCE +G W+ +P C P+ CG P G ++D+G
Sbjct: 2591 HAMQTCEESG-WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPH 2649
Query: 3086 -------------------------FSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQ 3120
F Y + VS++C+P L+G+P CQ DGTW+G+
Sbjct: 2650 PPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSA 2709
Query: 3121 PSCIDPTLTTCADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSG 3180
PSCI C P P+ G ++ +GS V + C+ G++L GS R CL N WSG
Sbjct: 2710 PSCIS---IECDLPTAPENGFLRFTE-TSMGSAVQYSCKPGHILAGSDLRLCLENRKWSG 2765
Query: 3181 TPPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTG 3240
P C C++P + ++ + + TL Y C G+ L G+E RTC+ D +W
Sbjct: 2766 ASPRCEAISCKKPNPVMNGSIKGSNYTYLS-TLYYECDPGYVL-NGTERRTCQDDKNWDE 2823
Query: 3241 KPPICLEVRPSGRPIN 3256
PIC+ V S P++
Sbjct: 2824 DEPICIPVDCSSPPVS 2839
Score = 430 bits (1106), Expect = e-119
Identities = 474/1938 (24%), Positives = 732/1938 (37%), Gaps = 294/1938 (15%)
Query: 1384 SCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCI- 1442
SC P +NG S D + AG + +QC+ GY L G + + C + W P+C+
Sbjct: 1689 SCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCT---DNGSWNGVSPSCLD 1745
Query: 1443 ---APCGGDLT------GPSGVILSPNYPEPYPPGKEC----DWKVTVSPD--------Y 1481
G D + G + P GK C K +P+ Y
Sbjct: 1746 VDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIY 1805
Query: 1482 VIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLP-------GRIESSSNSLF-- 1532
+ F+ + GY + G ++ L + +P G+ N
Sbjct: 1806 TVGAEVT-FSCQEGYQLM----GVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEE 1860
Query: 1533 LAFRSDASVS---NAGFVI------------DYTENPRE----SCFDPGSIKNGTRVGSD 1573
LAF + V+ N G+ + ++ +P C P +I NG + S
Sbjct: 1861 LAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSG 1920
Query: 1574 LKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAP-CGGQYVGSDGVVLS 1632
L S+ +Y C GY ++G S + C +W+ P C CG D V+
Sbjct: 1921 LTYLSTASYSCDTGYSLQGPSIIECT----ASGIWDRAPPACHLVFCGEPPAIKDAVITG 1976
Query: 1633 PNYPQNYTSGQICLYFVTVPK----DYVVFGQFAFFHTALNDV------VEVHDGHSQHS 1682
N+ T C T+ + + G+++ V + H
Sbjct: 1977 NNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAH 2036
Query: 1683 RLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPEPR 1742
RL ++ + + LA ++Q+L K + P Q +PR A C P
Sbjct: 2037 RLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEG------QDMPRCIAHFCEKPPSVS 2090
Query: 1743 YG---KRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPT--CV-VPC 1796
Y + F+ G++V F+C G+ L S +IEC+ QWN S + C+ V C
Sbjct: 2091 YSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECM----RGGQWNPSPMSIQCIPVRC 2146
Query: 1797 GGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGA 1856
G + G + + + +C + + + V G
Sbjct: 2147 GEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGE 2206
Query: 1857 DNTVT--MLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLS---SCPE 1911
V L +G + + N Y S + V A H ++ + C +
Sbjct: 2207 PPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGK 2266
Query: 1912 PAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPP-PLCI-AQCG 1969
P NG GE + V V F C GY L G + +C +WN P C+ A+C
Sbjct: 2267 PPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKS--GKWNKKSNPKCMPAKCP 2324
Query: 1970 G--------TVEEME---GVILSPGFPGNY---PSNMDC----SWKIALPV--------- 2002
++E+ GV+ G+ PS + C W + PV
Sbjct: 2325 EPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPP 2384
Query: 2003 ---GFGAHI--QFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVY 2057
FG I L+F + + + G + + G + P S+ V
Sbjct: 2385 PLISFGVPIPSSALHFGSTVKYSCV---GGFF----LRGNSTTLCQPDGTWSSPLPECVP 2437
Query: 2058 FHSDHSQNRPGFKLEYQDLTY-SHQISSFLRGFDLSELERTNSTPPVAASYVW-DLDPGC 2115
+ P ++ Q L Y S + + GF+L N+T + W P C
Sbjct: 2438 VECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELV----GNTTTLCGENGHWLGGKPTC 2493
Query: 2116 EAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPL 2175
+A EC P+ NG + GQ+VT+ C G++L G LTC +WD
Sbjct: 2494 KAI---ECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLE--TGDWDVDA 2548
Query: 2176 PKCE-VPCGGNITSSNGTV----YS----------PGFPSPYSSSQDCV---WLITVPIG 2217
P C + C NG V YS PGF + Q C W ++P
Sbjct: 2549 PSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESGWSSSIPT- 2607
Query: 2218 HGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAA 2277
+ ++ L GD + D G F + + + + +
Sbjct: 2608 -CMPIDCGLPPHIDFGDCTKLKDDQ-------GYF---------EQEDDMMEVPYVTPHP 2650
Query: 2278 TGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCK 2337
+ A+A + TK P T + F G +V Y C PG+ L+GN +L C+
Sbjct: 2651 PYHLGAVA-KTWENTKESP---------ATHSSNFLYGTMVSYTCNPGYELLGNPVLICQ 2700
Query: 2338 L-GTYLQFEGPPPIC---EVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDY 2393
GT+ G P C E PT ++ + +++ GS Q+ + D
Sbjct: 2701 EDGTW---NGSAPSCISIECDLPT---APENGFLRFTETSMGSAVQYSCKPGHILAGSDL 2754
Query: 2394 NISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHA 2453
+ L + SG SP +A+S
Sbjct: 2755 RLCLENRKW---------------SGASPRCEAIS------------------------- 2774
Query: 2454 YNRKGFKIRYSAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHP 2513
C P ++G I G T ++++ C+ GY L G C
Sbjct: 2775 --------------CKKPNPVMNGSIKGSNYTYL-STLYYECDPGYVLNGTERRTC---- 2815
Query: 2514 QGYHLWSEAIPLCQALSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAEC 2573
Q W E P+C + C P NG V G EYT + Y+C+EG+ L+ GA + C
Sbjct: 2816 QDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLE-GARSRV-C 2873
Query: 2574 LDTGLWSNRNVPPQCVPVTC--PDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYT 2631
L G WS P CVPV C P + V G Y F ++ C GY
Sbjct: 2874 LANGSWS--GATPDCVPVRCATPPQLANGVTEG-------LDYGFMKEVTFHCHEGYILH 2924
Query: 2632 GQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLV 2691
G + CQ++G W P C+ ++CG +G G ++G + C GY L
Sbjct: 2925 GAPKLTCQSDGNWDA--EIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLH 2982
Query: 2692 GSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGM 2751
G+ R C++NG WSGS CL C TP I G +NG ++ + QC GF+L+G+
Sbjct: 2983 GNSSRRCLSNGSWSGSSPSCLPCRCSTP-VIEYGTVNGTDFDCGKAARIQCFKGFKLLGL 3041
Query: 2752 SVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNST 2811
S C+ D WS P C SCG P++ +S S V+ YSC + G+S
Sbjct: 3042 SEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSD 3101
Query: 2812 RMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSS 2871
+C G W+ P C S CG P A+ + G++ + ++ C G+ + +
Sbjct: 3102 LICTEKGVWSQPYPVCEPLS---CGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDT 3158
Query: 2872 ER-TCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLL 2930
+ TCQ +G W + C C P ++ +V D + + C EGY G+
Sbjct: 3159 DTFTCQKDGRWFPERISCSPKKCPLPENITHI-LVHGDDFSVNRQVSVSCAEGYTFEGVN 3217
Query: 2931 SRHCSVNGTWTG--SDPECLVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHR 2988
C ++GTW SD C ++CG P P +G +G+ + + T+ YQC PGY +E +R
Sbjct: 3218 ISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNR 3277
Query: 2989 VSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPA 3048
V C ++R W+G +CK C+ P NGK + G +V Y+C GY L P+
Sbjct: 3278 ERV--CQENRQWSGGVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPS 3335
Query: 3049 VFTCEGNGSWTGELPQCFPVFCGDPGV-PSRGRREDRGFSYRSSVSFSCHPPLVLVGSPR 3107
C NG+W+ +P C P C P V P ++ F +VS C +L G
Sbjct: 3336 EAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGI 3395
Query: 3108 RFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGS 3167
C D TW+ T C +C P + I YQ G + + C GY+L+G
Sbjct: 3396 ITCNPDETWTQTSAKC---EKISCGPPAHVENAIARGVH-YQYGDMITYSCYSGYMLEGF 3451
Query: 3168 TTRTCLPNLTWSGTPPDC 3185
CL N TW+ +PP C
Sbjct: 3452 LRSVCLENGTWT-SPPIC 3468
Score = 411 bits (1056), Expect = e-114
Identities = 421/1801 (23%), Positives = 654/1801 (36%), Gaps = 322/1801 (17%)
Query: 1562 GSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTA-PCG 1620
GS+ + DLK GS V +C G+++ G C+ + W P P C CG
Sbjct: 1636 GSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCL----NQGQWTQPLPHCERISCG 1691
Query: 1621 GQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVF----GQFAFFHTALNDVVEVHD 1676
+G + ++ T C + D +F G + + DV E
Sbjct: 1692 VPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAV 1751
Query: 1677 GH--SQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQ 1734
G S+H+ L+ + GS+ +P T + K A +
Sbjct: 1752 GSDCSEHASCLN-VDGSYICSCVPPYTGD-------GKNCA---------------EPIK 1788
Query: 1735 CSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC-V 1793
C + P G G ++VGA V F C GY L G +I CL +WN P C
Sbjct: 1789 CKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLES----GEWNHLIPYCKA 1844
Query: 1794 VPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVF 1853
V CG P PE C+ ++ G+ + + T
Sbjct: 1845 VSCG-----------KPAIPEN-----GCIEELAFTFGSKVTYRCNKGYTL--------- 1879
Query: 1854 DGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPA 1913
D + L + S + P + C P
Sbjct: 1880 -AGDKESSCLANSSWSHSPPVCEPVK-----------------------------CSSPE 1909
Query: 1914 VPSNG--VKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLC-IAQCGG 1970
+NG + +G YL S+ C+ GY+LQG + I C + W+ PP C + CG
Sbjct: 1910 NINNGKYILSGLTYL--STASYSCDTGYSLQGPSIIECTASGI--WDRAPPACHLVFCGE 1965
Query: 1971 TVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYE 2030
+ VI F C L D IE
Sbjct: 1966 PPAIKDAVITGNNFTFRNTVTYTCKEGYTLA----------------GLDTIECLAD--- 2006
Query: 2031 TSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSFLRGFD 2090
G++S S+ +S V DH+ +L + D+ + + + D
Sbjct: 2007 -----GKWSRSDQQCLAVSCDEPPIV----DHASPETAHRL-FGDIAFYYCSDGYSLA-D 2055
Query: 2091 LSEL---ERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQSVTF 2147
S+L + PP P C A+ ++ P V A + G V+F
Sbjct: 2056 NSQLLCNAQGKWVPPEGQDM-----PRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSF 2110
Query: 2148 ECLPGYQLTGHPVLTCQHGTNRNWDHPLPKC-EVPCGGNITSSNGTV----YSPGFPSPY 2202
+C+ G+ L + C G N +C V CG + NG YS G Y
Sbjct: 2111 KCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAY 2170
Query: 2203 SSSQDCV--------------WLITVPIGHGVRLNLSLLQTEP---SGDFITIWDG---P 2242
S ++ W +P H V EP F+ G
Sbjct: 2171 SCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCG------EPPKVENGFLEHTTGRIFE 2224
Query: 2243 QQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILPN 2302
+ + +S+ +N+ +H ++ PL PP P
Sbjct: 2225 SEVRYQCNPGYKSVGSPVFVCQANR---HWHSESP--------LMCVPLDCGKPP---PI 2270
Query: 2303 AEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLT 2362
+ E F +G V++ C G+ LVG+ TC+ + P CP LL
Sbjct: 2271 QNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLE 2330
Query: 2363 DSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSP 2422
+ ++L + LT E + E + GPS
Sbjct: 2331 NQ--LVLKE-------------------------LTTEVGVVTFSCKEGHVLQGPS---- 2359
Query: 2423 LLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAPLHGFILGQ 2482
+LK L +W+ + C+ P G +
Sbjct: 2360 VLKCLPSQ----------------QWNDSFPVCK--------IVLCTPPPLISFGVPIPS 2395
Query: 2483 TSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMV 2542
++ G ++ + C G+ L G+S +C P G WS +P C + C PE NG++
Sbjct: 2396 SALHFGSTVKYSCVGGFFLRGNSTTLC--QPDG--TWSSPLPECVPVECPQPEEIPNGII 2451
Query: 2543 FGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVE 2602
+ + A+Y+C G+ L T C + G W P C + C + +
Sbjct: 2452 DVQGLAYLSTALYTCKPGFELVGNT--TTLCGENGHWLGGK--PTCKAIEC--LKPKEIL 2505
Query: 2603 HGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELP 2662
+G++ T + + C+ G+ G + C G W + P+C I C
Sbjct: 2506 NGKFSY---TDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDV--DAPSCNAIHCDSPQ 2560
Query: 2663 IPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPE-- 2720
NG G YGA I+SC G+ + G ++ C +G WS S C+ CG P
Sbjct: 2561 PIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTCMPIDCGLPPHI 2619
Query: 2721 ------------------------PIVNGH--------------------INGENYSYRG 2736
P V H + N+ Y
Sbjct: 2620 DFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGT 2679
Query: 2737 SVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVV 2796
V Y CN G+ L+G V ICQ+D W+G P C+ + C P +P + + ++G+ V
Sbjct: 2680 MVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAV 2739
Query: 2797 RYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTV 2856
+YSC L G+ R+C + W+G+ P C S C P +G G ++ +
Sbjct: 2740 QYSCKPGHILAGSDLRLCLENRKWSGASPRCEAIS---CKKPNPVMNGSIKGSNYTYLST 2796
Query: 2857 MRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSI 2916
+ + C+ G+VL G+ RTCQ + +W +P C + C +P +N + V D F I
Sbjct: 2797 LYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQ-VRGDEYTFQKEI 2855
Query: 2917 VYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGNDFRYNKTVTY 2976
Y C EG+ G SR C NG+W+G+ P+C+ + C P ANG+ G D+ + K VT+
Sbjct: 2856 EYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTF 2915
Query: 2977 QCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSSVTY 3036
C GY++ H L+C D W+ P+CK + C PP + +G G F+ G + Y
Sbjct: 2916 HCHEGYIL--HGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQY 2973
Query: 3037 ACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGRREDRGFSYRSSVSFSC 3096
C GY+L + C NGSW+G P C P C P V G F + C
Sbjct: 2974 QCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTP-VIEYGTVNGTDFDCGKAARIQC 3032
Query: 3097 HPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCAD-PGVPQFGIQNNSQGYQVGSTVL 3155
L+G C++DG WS P C T+C P +P I S + + +
Sbjct: 3033 FKGFKLLGLSEITCEADGQWSSGFPHC---EHTSCGSLPMIPNAFISETSSWKE--NVIT 3087
Query: 3156 FRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPSMGYTLIY 3215
+ C+ GY++QGS+ C WS P C P C P + +A V + + +
Sbjct: 3088 YSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANA-VATGEAHTYESEVKL 3146
Query: 3216 SCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRPINTAREPPLTQALIPGDVFAK 3275
C EG+++ ++ TC+ DG W R S P +T L+ GD F+
Sbjct: 3147 RCLEGYTMDTDTDTFTCQKDGRW-------FPERISCSPKKCPLPENITHILVHGDDFSV 3199
Query: 3276 N 3276
N
Sbjct: 3200 N 3200
Score = 395 bits (1016), Expect = e-109
Identities = 363/1367 (26%), Positives = 544/1367 (39%), Gaps = 124/1367 (9%)
Query: 1908 SCPEPAVPSNGV---KTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPL- 1963
SC EP NG TG + V +QC PGY G C R W+ PL
Sbjct: 2203 SCGEPPKVENGFLEHTTGR--IFESEVRYQCNPGYKSVGSPVFVCQAN--RHWHSESPLM 2258
Query: 1964 CIA-QCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYI 2022
C+ CG G + F G+ +QF N Y
Sbjct: 2259 CVPLDCGKPPPIQNGFMKGENFE------------------VGSKVQFFC-----NEGYE 2295
Query: 2023 EIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQI 2082
+ + + T + G+++ P + + E + ++ E +T+S +
Sbjct: 2296 LVGDSSW-TCQKSGKWNKKSNPKCMPAKCPEPPLL---ENQLVLKELTTEVGVVTFSCKE 2351
Query: 2083 SSFLRGFDLSELERTNSTPPVAASYVW-DLDPGCEAYELQECPDPEPFANGI-VRGAGYN 2140
L+G S S W D P C+ + C P + G+ + + +
Sbjct: 2352 GHVLQG---------PSVLKCLPSQQWNDSFPVCK---IVLCTPPPLISFGVPIPSSALH 2399
Query: 2141 VGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKC-EVPCGGNITSSNGTVYSPGFP 2199
G +V + C+ G+ L G+ CQ + W PLP+C V C NG + G
Sbjct: 2400 FGSTVKYSCVGGFFLRGNSTTLCQ--PDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLA 2457
Query: 2200 SPYSSSQDCVWLITVPIGHGVRL---NLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSM 2256
++ C + +G+ L N L +P+ I P++ +T
Sbjct: 2458 YLSTALYTCKPGFEL-VGNTTTLCGENGHWLGGKPTCKAIECLK-PKEILNGKFSYTDLH 2515
Query: 2257 AKKTVQSSSNQVLLKFHRDAAT---GGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFN 2313
+TV S N+ A T G + + + C P + N V E +++
Sbjct: 2516 YGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFV--EGADYS 2573
Query: 2314 IGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHC--PTNELLTDSTGVILSQ 2371
G I+ Y C PGF + G+ + TC+ + P + C P + D T + Q
Sbjct: 2574 YGAIIIYSCFPGFQVAGHAMQTCEESGWSS--SIPTCMPIDCGLPPHIDFGDCTKLKDDQ 2631
Query: 2372 SYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNY 2431
Y + V P Y++ + + + K+ SP S N+
Sbjct: 2632 GYFEQEDDMMEVPY-VTPHPPYHLGAVAKTWENTKE-------------SPATH--SSNF 2675
Query: 2432 SAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYC-----SLPRAPLHGFILGQTSTQ 2486
+V+ + N Y + ++ SAP C LP AP +GF L T T
Sbjct: 2676 LYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGF-LRFTETS 2734
Query: 2487 PGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGKE 2546
G ++ + C G+ L G + +C + + WS A P C+A+SC P NG + G
Sbjct: 2735 MGSAVQYSCKPGHILAGSDLRLCLENRK----WSGASPRCEAISCKKPNPVMNGSIKGSN 2790
Query: 2547 YTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTC--PDVSSISVEHG 2604
YT + Y C GY L T C D W P C+PV C P VS+ G
Sbjct: 2791 YTYLSTLYYECDPGYVLNGTERRT--CQDDKNWDEDE--PICIPVDCSSPPVSANGQVRG 2846
Query: 2605 RWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIP 2664
+Y FQ ++ C+ G+ G R C ANG WS +TP C + C P
Sbjct: 2847 -------DEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWS--GATPDCVPVRCATPPQL 2897
Query: 2665 PNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVN 2724
NG G + F C+ GY L G+ C ++G W C +CG PE + +
Sbjct: 2898 ANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAH 2957
Query: 2725 GHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQ 2784
G NG ++ + G + YQC G++L G S R C + WSG +P C+ C P +
Sbjct: 2958 GFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIE-YGT 3016
Query: 2785 MSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHG 2844
++G + G R C L+G S C DG W+ PHC TS G P IP
Sbjct: 3017 VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSL--PMIPNAF 3074
Query: 2845 IRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNARV 2904
I S+ V+ +SC +G+V++GSS+ C G WS P C +SCG+P + +NA V
Sbjct: 3075 ISETSSWKEN-VITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANA-V 3132
Query: 2905 VFSDGLVFSSSIVYECREGYYA-TGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLR 2963
+ + S + C EGY T + C +G W C C P + L
Sbjct: 3133 ATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILV 3192
Query: 2964 LGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNG--TKPVCKALMCKPPPLIPNG 3021
G+DF N+ V+ C GY E +SV C D TW + C + C P +G
Sbjct: 3193 HGDDFSVNRQVSVSCAEGYTFEGVNISV--CQLDGTWEPPFSDESCSPVSCGKPESPEHG 3250
Query: 3022 KVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGRR 3081
VVGS + + S++ Y C GY+L C+ N W+G + C C P G+
Sbjct: 3251 FVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKA 3310
Query: 3082 EDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGI 3141
+ + +V +SC+ L G C +GTWS P C C P V
Sbjct: 3311 DIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLC---KPNPCPVPFVIPENA 3367
Query: 3142 QNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANV 3201
+ + + V V +C++G+LLQG TC P+ TW+ T C C P +A
Sbjct: 3368 LLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIA 3427
Query: 3202 GALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEV 3248
+ G + YSC G+ L+ G C +G+WT PPIC V
Sbjct: 3428 RGVHY-QYGDMITYSCYSGYMLE-GFLRSVCLENGTWT-SPPICRAV 3471
Score = 392 bits (1007), Expect = e-108
Identities = 284/1013 (28%), Positives = 422/1013 (41%), Gaps = 92/1013 (9%)
Query: 2293 KCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICE 2352
KCP P +L N ++V + +G +V + C G L G +L C Q+ P+C+
Sbjct: 2322 KCPEPPLLEN-QLVLKELTTEVG-VVTFSCKEGHVLQGPSVLKCLPSQ--QWNDSFPVCK 2377
Query: 2353 -VHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWL-------VRVEPDYNISLTVEYFLS 2404
V C L++ + S + GS ++ +PD S + +
Sbjct: 2378 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2437
Query: 2405 EKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYS 2464
+ EI +G L + Y+ N+ L + H G K
Sbjct: 2438 VECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWL---GGKPTCK 2494
Query: 2465 APYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIP 2524
A C P+ L+G T G ++ + CN G+RL G S C W P
Sbjct: 2495 AIECLKPKEILNGKF-SYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGD----WDVDAP 2549
Query: 2525 LCQALSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNV 2584
C A+ C P+ +NG V G +Y+ G +YSC G+ Q A C ++G WS+
Sbjct: 2550 SCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGF--QVAGHAMQTCEESG-WSSSI- 2605
Query: 2585 PPQCVPVTCP--------DVSSISVEHG---------------------------RWRLI 2609
P C+P+ C D + + + G W
Sbjct: 2606 -PTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENT 2664
Query: 2610 FET------QYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPI 2663
E+ + + + C+PGY G V+ CQ +G W+ S P+C I C
Sbjct: 2665 KESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWN--GSAPSCISIECDLPTA 2722
Query: 2664 PPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIV 2723
P NG T + G+ +SC G+ L GS +R C+ N WSG+ RC A C P P++
Sbjct: 2723 PENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVM 2782
Query: 2724 NGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHS 2783
NG I G NY+Y ++ Y+C+ G+ L G R CQ D +W P C+ V C P +
Sbjct: 2783 NGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANG 2842
Query: 2784 QMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAH 2843
Q+ GD YT + Y+C L G +R+C +G W+G+ P C C P A+
Sbjct: 2843 QVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVR---CATPPQLAN 2899
Query: 2844 GIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNAR 2903
G+ G + + F C G++L G+ + TCQ++G+W P C ++CG P ++
Sbjct: 2900 GVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHG- 2958
Query: 2904 VVFSDGLVF--SSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANG 2961
F +G F I Y+C GY G SR C NG+W+GS P CL C P I G
Sbjct: 2959 --FPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVI-EYG 3015
Query: 2962 LRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNG 3021
G DF K QC G+ + +S ++C D W+ P C+ C P+IPN
Sbjct: 3016 TVNGTDFDCGKAARIQCFKGFKLLG--LSEITCEADGQWSSGFPHCEHTSCGSLPMIPNA 3073
Query: 3022 KVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGRR 3081
+ + + +TY+C GY + + C G W+ P C P+ CG P +
Sbjct: 3074 FISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVA 3133
Query: 3082 EDRGFSYRSSVSFSCHPPLVLVGSPRRF-CQSDGTWSGTQPSCIDPTLTTCADPGVPQFG 3140
+Y S V C + F CQ DG W + SC + C P
Sbjct: 3134 TGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISC---SPKKCPLPENITH- 3189
Query: 3141 IQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPP----DCVPHHCRQPETP 3196
I + + V V C +GY +G C + TW PP C P C +PE+P
Sbjct: 3190 ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWE--PPFSDESCSPVSCGKPESP 3247
Query: 3197 THANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVR 3249
H V + T+IY C+ G+ L+G E R C+ + W+G IC E R
Sbjct: 3248 EHGFVVGSKY-TFESTIIYQCEPGYELEGNRE-RVCQENRQWSGGVAICKETR 3298
Score = 296 bits (759), Expect = 2e-79
Identities = 387/1656 (23%), Positives = 591/1656 (35%), Gaps = 275/1656 (16%)
Query: 1557 SCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCT 1616
SC +P + + + + G YYC GY + S L C P P C
Sbjct: 2020 SCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCI 2079
Query: 1617 APCGGQYVGSDGVVLSPNYPQNYTSGQICLY-----FVTVPKDYVVFGQFAFFHTALNDV 1671
A + +L + +G + + FV + + ++ + +
Sbjct: 2080 AHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSI 2139
Query: 1672 --VEVHDGHSQHSRLLSSLSGSHT--GESLPLATSNQVLIKFSAKGLAPARGFHFVYQAV 1727
+ V G S + SGS+ G + + + IK K A G +
Sbjct: 2140 QCIPVRCGEPP-SIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWS--SPI 2196
Query: 1728 PRTSATQCSSVPEPRYGKRLGSDFSVGAI----VRFECNSGYALQGSPEIECLPVPGALA 1783
P C P+ G + + G I VR++CN GY GSP C A
Sbjct: 2197 PTCHPVSCGEPPKVENGFL---EHTTGRIFESEVRYQCNPGYKSVGSPVFVCQ----ANR 2249
Query: 1784 QWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVT 1843
W+ +P VP L G P P N + E + +V F
Sbjct: 2250 HWHSESPLMCVP------------LDCGKPPPIQNGF------MKGENFEVGSKVQFFCN 2291
Query: 1844 EQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 1903
E E+ + T G ++ + P + +
Sbjct: 2292 E----GYELVGDSSWTCQKSGKWNKKSNPKCMPA-------------------------- 2321
Query: 1904 VGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWN----- 1958
CPEP + N + E VV+F C+ G+ LQG + + C+P ++WN
Sbjct: 2322 ----KCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPS--QQWNDSFPV 2375
Query: 1959 ------YPPPLC---------IAQCGGTVEE--MEGVILSPGFPGNYPS--NMDCSWKIA 1999
PPPL G TV+ + G L GN + D +W
Sbjct: 2376 CKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLR----GNSTTLCQPDGTWSSP 2431
Query: 2000 LPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFH 2059
LP ++ PN I+++ Y ++ + G EL + + E +
Sbjct: 2432 LPEC--VPVECPQPEEIPN-GIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLG 2488
Query: 2060 SDHSQN-----RP----GFKLEYQDLTYSHQIS-SFLRGFDLSELERTNSTPPVAASYVW 2109
+ +P K Y DL Y ++ S RGF L S + W
Sbjct: 2489 GKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEG----PSALTCLETGDW 2544
Query: 2110 DLD-PGCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTN 2168
D+D P C A C P+P NG V GA Y+ G + + C PG+Q+ GH + TC+
Sbjct: 2545 DVDAPSCNAIH---CDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEES-- 2599
Query: 2169 RNWDHPLPKC-EVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLL 2227
W +P C + CG G Y +D + + H
Sbjct: 2600 -GWSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPH--------- 2649
Query: 2228 QTEPSGDFITIWDGPQQTAPR------LGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGI 2281
G W+ +++ G + N VL+ D G
Sbjct: 2650 PPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLI-CQEDGTWNGS 2708
Query: 2282 FAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTY 2341
S +C PT N + E ++G V+Y C PG L G+++ C
Sbjct: 2709 APSCISI----ECDLPTAPENGFL--RFTETSMGSAVQYSCKPGHILAGSDLRLCLENR- 2761
Query: 2342 LQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGS-YPQFQTCSWLVRVEPDYNISLTVE 2400
++ G P CE + +++ S GS Y T + +P Y ++ T
Sbjct: 2762 -KWSGASPRCEA------ISCKKPNPVMNGSIKGSNYTYLSTLYY--ECDPGYVLNGTER 2812
Query: 2401 YFLSE-KQYDEFEIFDGPSGQSPLLKALSGN-----YSAPLIVTSSSNSVYLRWSSDHAY 2454
+ K +DE E P S + +G Y+ + + N +L +
Sbjct: 2813 RTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRV 2872
Query: 2455 NRKGFKIRYSAPYCSLPRAPLHGFIL-GQTSTQPGG---SIHFGCNAGYRLVGHSMAICT 2510
+ P C R + G T G + F C+ GY L G C
Sbjct: 2873 CLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTC- 2931
Query: 2511 RHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEAT 2570
Q W IPLC+ ++CG PE +G G + G Y C GY L + +
Sbjct: 2932 ---QSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNS--S 2986
Query: 2571 AECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYY 2630
CL G WS + P C+P C S+ +E+G + T + + C G+
Sbjct: 2987 RRCLSNGSWSGSS--PSCLPCRC---STPVIEYGT---VNGTDFDCGKAARIQCFKGFKL 3038
Query: 2631 TGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTL 2690
G I C+A+G+WS G P C SCG LP+ PN T S +SC SGY +
Sbjct: 3039 LGLSEITCEADGQWSSG--FPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCRSGYVI 3096
Query: 2691 VGSRVRECMANGLWS-----------GS--------------------EVRCLAGH---- 2715
GS C G+WS GS ++RCL G+
Sbjct: 3097 QGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDT 3156
Query: 2716 ------------------------CGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGM 2751
C PE I + ++G+++S V C G+ G+
Sbjct: 3157 DTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGV 3216
Query: 2752 SVRICQQDHHWSGKTPF----CVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLV 2807
++ +CQ D W + PF C VSCG P SP H + G YT + + Y C L
Sbjct: 3217 NISVCQLDGTW--EPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELE 3274
Query: 2808 GNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVL 2867
GN R+C + W+G + C T C P +G ++ G + +SC G+ L
Sbjct: 3275 GNRERVCQENRQWSGGVAICKETR---CETPLEFLNGKADIENRTTGPNVVYSCNRGYSL 3331
Query: 2868 RGSSERTCQANGSWSGSQPECGVISCGNPGT-PSNARVVFSDGLVFSSSIVYECREGYYA 2926
G SE C NG+WS P C C P P NA + + V ++ +CREG+
Sbjct: 3332 EGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYV-DQNVSIKCREGFLL 3390
Query: 2927 TGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMES 2986
G C+ + TWT + +C I+CG P N + G ++Y +TY C GYM+E
Sbjct: 3391 QGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEG 3450
Query: 2987 HRVSVLSCTKDRTWNGTKPVCKALM---CKPPPLIPNGKVVGSDFMWGSSV------TYA 3037
SV C ++ TW + P+C+A+ C+ + W +
Sbjct: 3451 FLRSV--CLENGTWT-SPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILP 3507
Query: 3038 CLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDP 3073
CL G + P + C+ WTG +C C P
Sbjct: 3508 CLNGGRCVAP--YQCDCPPGWTGS--RCHTAVCQSP 3539
Score = 130 bits (328), Expect = 2e-29
Identities = 85/286 (29%), Positives = 122/286 (42%), Gaps = 45/286 (15%)
Query: 3008 KALMCKPPPL----IPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELP 3063
K++ C P +P+ + D GS V C G+QL V C G WT LP
Sbjct: 1624 KSIFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLP 1683
Query: 3064 QCFPVFCGDPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSC 3123
C + CG P G F S+V++ C+ L+G R FC +G+W+G PSC
Sbjct: 1684 HCERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSC 1743
Query: 3124 ID----------------------------PTLT----------TCADPGVPQFGIQNNS 3145
+D P T C PG P+ G ++
Sbjct: 1744 LDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENG-HSSG 1802
Query: 3146 QGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALD 3205
+ Y VG+ V F CQ+GY L G T TCL + W+ P C C +P P + + L
Sbjct: 1803 EIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELA 1862
Query: 3206 LPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPS 3251
+ G + Y C +G++L G E +C A+ SW+ PP+C V+ S
Sbjct: 1863 F-TFGSKVTYRCNKGYTLAGDKE-SSCLANSSWSHSPPVCEPVKCS 1906
Score = 114 bits (284), Expect = 2e-24
Identities = 256/1225 (20%), Positives = 405/1225 (33%), Gaps = 339/1225 (27%)
Query: 343 CPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDH-RPVCR 401
C P + G G +F +GS VQF CNEGY+L G TC K W+ P C
Sbjct: 2264 CGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGK----WNKKSNPKCM 2319
Query: 402 ARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLT 461
C P P+ + +L +E E G T +
Sbjct: 2320 PAKC-------------PEPPLLEN------------------QLVLKELTTEVGVVTFS 2348
Query: 462 VGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSC 521
+G ++L G SV + S Q W S+ + C
Sbjct: 2349 CKEG----------HVLQGPSVLKCLPS---QQW--------------NDSFPVCKIVLC 2381
Query: 522 GDPGIPAYGRR-EGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFF 580
P + ++G S H G T+K+ C F L G CQ + WS+ P C
Sbjct: 2382 TPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPEC------ 2435
Query: 581 NFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATA 640
V + PE+ N + V + +L+ +P F+ +
Sbjct: 2436 -------VPVECPQPEEIPNGIIDV-------QGLAYLSTALYTCKPGFELV-------- 2473
Query: 641 EAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNG 700
G+ L + H G + T + EC P +NG
Sbjct: 2474 --------------------GNTTTLCGENGHWLGGK------PTCKAIECLKPKEILNG 2507
Query: 701 KRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWN-----SAVLRCEAP---- 751
K L G ++++ C+ GF +G +TC L+ G W+ + C++P
Sbjct: 2508 KFSYTDLHYGQTVTYSCNRGFR-LEGPSALTC-LETGD--WDVDAPSCNAIHCDSPQPIE 2563
Query: 752 ---CGGHLTSPSGTILSPGWPGFY------KDALSCAWVIEAQPGYPI------------ 790
G S I+ +PGF + W PI
Sbjct: 2564 NGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESGWSSSIPTCMPIDCGLPPHIDFGD 2623
Query: 791 --KITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSH 848
K+ D+ E D +EV + +G T ++ L+ T S+
Sbjct: 2624 CTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSY 2683
Query: 849 S-DIGFQLRYETITL-QSD-------------HCLDPGIPVNGQRHGNDFYVGALVTFSC 893
+ + G++L + + Q D C P P NG + +G+ V +SC
Sbjct: 2684 TCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSC 2743
Query: 894 DSGYTLSDGEPLECEPNFQWSRALPSCEALC--------GGFIQGSSGTILS-------P 938
G+ L+ + C N +WS A P CEA+ G I+GS+ T LS P
Sbjct: 2744 KPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDP 2803
Query: 939 GF--------------------PDFYPNNLNCTWIIETSHGKGVFFTFHT---------F 969
G+ P P + + + +G +TF F
Sbjct: 2804 GYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGF 2863
Query: 970 HLESGHDYLLITENGSFTQ------PLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMS 1023
LE + + NGS++ P+R T +L ++ GL F +V F
Sbjct: 2864 LLEGARSRVCLA-NGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTF-----HC 2917
Query: 1024 YEGFNI---------TFSEYDLE-------PCEEPEVPAYSIRKGLQFGVGDTLTFSCFP 1067
+EG+ + + +D E C PE A+ G F G + + CFP
Sbjct: 2918 HEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFP 2977
Query: 1068 GYRLEGTARITCLGGRRRLWSSPLPRCV-AECGNSVTGTQGTLLSPNFPVNYNNNHECIY 1126
GY+L G + CL WS P C+ C V GT+ +F +C
Sbjct: 2978 GYKLHGNSSRRCLSNGS--WSGSSPSCLPCRCSTPVI-EYGTVNGTDF--------DCGK 3026
Query: 1127 SIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWL 1186
+ + Q KG +L LSE + + W
Sbjct: 3027 AARIQCFKGFKL----LGLSE-----------------------------ITCEADGQWS 3053
Query: 1187 DFITDAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRG 1246
E+TS G S +I + + + + +++SC GY ++G
Sbjct: 3054 SGFPHCEHTSCG------SLPMIP---------NAFISETSSWKENVITYSCRSGYVIQG 3098
Query: 1247 SEELLCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEA 1306
S +L+C E+ W +P P C G+ + + E L C+
Sbjct: 3099 SSDLICT--EKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCL------E 3150
Query: 1307 GCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDL-----HSTFNSVVLQ 1361
G T+ F ++ DG + LP+++ H SV Q
Sbjct: 3151 GYTMDTDTDTFTCQK--------DGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQ 3202
Query: 1362 FSTDFFTSKQGFAIQFSV---------------STATSCNDPGIPQNGSRSGDSWEAGDS 1406
S + SV + SC P P++G G + +
Sbjct: 3203 VSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFEST 3262
Query: 1407 TVFQCDPGYALQGSAEISCVKIENR 1431
++QC+PGY L+G+ E C ENR
Sbjct: 3263 IIYQCEPGYELEGNRERVCQ--ENR 3285
Score = 108 bits (270), Expect = 9e-23
Identities = 335/1624 (20%), Positives = 523/1624 (32%), Gaps = 404/1624 (24%)
Query: 690 ECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCE 749
+C PG P NG G+ +G+ ++F C EG+ G ITC L+ G WN + C+
Sbjct: 1788 KCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQ-LMGVTKITC-LESGE--WNHLIPYCK 1843
Query: 750 A-PCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEV 808
A CG +G I + K C GY + + +
Sbjct: 1844 AVSCGKPAIPENGCIEELAFTFGSKVTYRC------NKGYTLAGDKE--------SSCLA 1889
Query: 809 RDGRTYSAPLIGVYHGTQVP-----QFLISTSNYLYLLFSTDKSHSDIGFQLRYETI--- 860
++S P+ + ++++S YL ST D G+ L+ +I
Sbjct: 1890 NSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYL----STASYSCDTGYSLQGPSIIEC 1945
Query: 861 -----------TLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEP 909
C +P + GN+F VT++C GYTL+ + +EC
Sbjct: 1946 TASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLA 2005
Query: 910 NFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSH---GKGVFFTF 966
+ +WSR+ C A + I+ P ET+H G F+
Sbjct: 2006 DGKWSRSDQQCLA-----VSCDEPPIVDHASP-------------ETAHRLFGDIAFYYC 2047
Query: 967 HTFHLESGHDYLLITENGSFTQPLRQ-------------------LTGSRLPAPISAGLY 1007
+ + + LL G + P Q + S A +AG
Sbjct: 2048 SDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSV 2107
Query: 1008 GNFTAQVRFISDFSMSYE-----GFNITFSEYDLEP--CEEPEVPAYSIRKGLQFGVGDT 1060
+F F+ + S E +N + P C EP G + G
Sbjct: 2108 VSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAM 2167
Query: 1061 LTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRC-VAECGNSVTGTQGTLLSPNFPVNYN 1119
+ +SC G+ ++G + TC + WSSP+P C CG G L +
Sbjct: 2168 VAYSCNKGFYIKGEKKSTCEATGQ--WSSPIPTCHPVSCGEPPKVENGFLEHTTGRI--- 2222
Query: 1120 NNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNS 1179
E Q PG S G + V N + S S +M V L+
Sbjct: 2223 --FESEVRYQCNPGYK----------SVGSPVFVCQANRHW------HSESPLMCVPLDC 2264
Query: 1180 TSSSLWLDFITDAENTSKGFELHF---SSFELI------------------------KCE 1212
+ EN G ++ F +EL+ KC
Sbjct: 2265 GKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCP 2324
Query: 1213 DPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTC-VAEC 1271
+P + + + G V+FSC G+ L+G L CL ++ W+ P C + C
Sbjct: 2325 EPPLLENQLVLKELTTEVGV-VTFSCKEGHVLQGPSVLKCLPSQQ--WNDSFPVCKIVLC 2381
Query: 1272 GGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDG 1331
++S G P P L+ T++ +G FL ++ + W
Sbjct: 2382 -------TPPPLISFGVPIP-SSALHFGSTVKYSC---VGGFFLRGNSTTLCQPDGTWSS 2430
Query: 1332 PVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVST---------- 1381
P+ V ++ +P + L ST +T K GF + + +T
Sbjct: 2431 PLPECVPVECPQPEEIPNGIIDVQGLAYL--STALYTCKPGFELVGNTTTLCGENGHWLG 2488
Query: 1382 ------ATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQ 1435
A C P NG S G + + C+ G+ L+G + ++C++ + W
Sbjct: 2489 GKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGD---WD 2545
Query: 1436 PSPPTCIA-PC------------GGDLTGPSGVILS--PNYPEPYPPGKECD---WKVTV 1477
P+C A C G D + + +I S P + + C+ W ++
Sbjct: 2546 VDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESGWSSSI 2605
Query: 1478 SPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRS 1537
I L P DF +D G E + + + + +
Sbjct: 2606 PTCMPIDC-----GLPPHIDFGDCTKLKDD-------------QGYFEQEDDMMEVPYVT 2647
Query: 1538 DASVSNAGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLS 1597
+ G V EN +ES S+ G+ V+Y C+ GYE+ G L
Sbjct: 2648 PHPPYHLGAVAKTWENTKES---------PATHSSNFLYGTMVSYTCNPGYELLGNPVLI 2698
Query: 1598 CILGPDGKPVWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVV 1657
C DG WN P C + + D P P+N
Sbjct: 2699 C--QEDG--TWNGSAPSCIS------IECD----LPTAPEN------------------- 2725
Query: 1658 FGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGSH--TGESLPLATSNQVLIKFSAKGLA 1715
G F T++ V+ S H G L L N+ K+S
Sbjct: 2726 -GFLRFTETSMGSAVQY------------SCKPGHILAGSDLRLCLENR---KWSG---- 2765
Query: 1716 PARGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIEC 1775
A PR A C G GS+++ + + +EC+ GY L G+ C
Sbjct: 2766 ----------ASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTC 2815
Query: 1776 LPVPGALAQWNVSAPTCV-VPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGI 1834
W+ P C+ V C G + +
Sbjct: 2816 QDD----KNWDEDEPICIPVDCSSPPVSANGQVRGDEY---------------------- 2849
Query: 1835 QIQVVSFVTEQNWDSLEVF--DGADNTVTML-GSFSGTT---VPALLNSTSNQLYLHFYS 1888
+F E + E F +GA + V + GS+SG T VP
Sbjct: 2850 -----TFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPV--------------- 2889
Query: 1889 DISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHIS 1948
C P +NGV G Y V+F C GY L G ++
Sbjct: 2890 -------------------RCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLT 2930
Query: 1949 CMPGTVRRWNYPPPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHI 2008
C + W+ PLC G E+ L+ GFP + G HI
Sbjct: 2931 CQ--SDGNWDAEIPLCKPVNCGPPED-----LAHGFPNGF------------SFIHGGHI 2971
Query: 2009 QFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPG 2068
Q+ F P + ++ G +SGS PS L + + + + +
Sbjct: 2972 QYQCF---PGY---KLHGNSSRRCLSNGSWSGSS-PSCLPCRCSTPVIEYGTVNGTD--- 3021
Query: 2069 FKLEYQDLTYSHQISSFLRGFDLSELERTNSTPPVAASYVWDLD-PGCEAYELQECPDPE 2127
D + +I F +GF L L S A W P CE C
Sbjct: 3022 -----FDCGKAARIQCF-KGFKLLGL----SEITCEADGQWSSGFPHCEH---TSCGSLP 3068
Query: 2128 PFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCE-VPCGGNI 2186
N + +T+ C GY + G L C W P P CE + CG
Sbjct: 3069 MIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTE--KGVWSQPYPVCEPLSCGSPP 3126
Query: 2187 TSSN 2190
+ +N
Sbjct: 3127 SVAN 3130
Score = 106 bits (264), Expect = 5e-22
Identities = 228/1069 (21%), Positives = 358/1069 (33%), Gaps = 255/1069 (23%)
Query: 139 CGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRA 198
CG P + NG GS ++ G V YSCN GF+++G TC A + W P+P+C
Sbjct: 2146 CGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEA----TGQWSSPIPTCH- 2200
Query: 199 DDACGGTLRGQSGII---SSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDF 255
+CG + ++G + + F SE + +Q GY
Sbjct: 2201 PVSCGEPPKVENGFLEHTTGRIFESE-----------------------VRYQCNPGYKS 2237
Query: 256 L--EVTGTEGSSLWFTGASL---------PAPV----ISSKNW---LRLHFTSDGNHRQR 297
+ V + + W + + L P P+ + +N+ ++ F + +
Sbjct: 2238 VGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELV 2297
Query: 298 GFSAQYQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGS 357
G S+ K K K MP+K CP+P + E L
Sbjct: 2298 GDSSWTCQKSGKWNKKSNPKCMPAK--------------------CPEPPLLENQLVLKE 2337
Query: 358 DFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIIT 417
V F+C EG+ LQG + C+ W+D PVC+ +C P +I
Sbjct: 2338 LTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQ----WNDSFPVCKIVLCT-----PPPLI- 2387
Query: 418 SPNFPIQYDNNAHCVWIITALNPSKVIKLA-FEEFDLERGYDTLTVGDGGQDGDQKTVLY 476
S PI +AL+ +K + F L TL DG +
Sbjct: 2388 SFGVPIP----------SSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2437
Query: 477 I--LTGTSVPDLIVSTNHQMWLL---------FQTDG--------SGSSLGFKASYEEIE 517
+ +P+ I+ +L F+ G +G LG K + + IE
Sbjct: 2438 VECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIE 2497
Query: 518 QGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGC--- 574
C P G+ + H+G T+ + C F L G A+TC + W P C
Sbjct: 2498 ---CLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAI 2554
Query: 575 ------------------------VFSCFFNFTSPSGVVLSPNYPEDYGNHL-HCVWLIL 609
++SCF F +G + + + + C+ +
Sbjct: 2555 HCDSPQPIENGFVEGADYSYGAIIIYSCFPGF-QVAGHAMQTCEESGWSSSIPTCMPIDC 2613
Query: 610 ARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQ 669
P H+ F D ++ E P + P G VA+
Sbjct: 2614 GLPP---HIDFGDCTKLKDDQGYFEQEDDMMEVPYV-------TPHPPYHLGAVAKTWEN 2663
Query: 670 TDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSET 729
T S N + T C +PG + LG+ + +C E GT
Sbjct: 2664 TKESPATHSSNFLYGTMVSYTC-NPGYEL----------LGNPV-LICQED--GTWNGSA 2709
Query: 730 ITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYP 789
+C+ + C+ P T+P G+ F + ++ A +PG+
Sbjct: 2710 PSCI-----------SIECDLP-----TAPEN-----GFLRFTETSMGSAVQYSCKPGHI 2748
Query: 790 IKITFDRFKTEVNYDTLEVR--DGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKS 847
+ + R LE R G + I V I SNY YL ST
Sbjct: 2749 LAGSDLRL-------CLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYL--STLYY 2799
Query: 848 HSDIGFQLR-YETITLQSD-------------HCLDPGIPVNGQRHGNDFYVGALVTFSC 893
D G+ L E T Q D C P + NGQ G+++ + ++C
Sbjct: 2800 ECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTC 2859
Query: 894 DSGYTLSDGEPLECEPNFQWSRALPSCEAL-CGGFIQGSSGTILSPGFPDFYPNNLNCTW 952
+ G+ L C N WS A P C + C Q ++G T
Sbjct: 2860 NEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGV----------------TE 2903
Query: 953 IIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQ--PLRQLTGSRLPAPISAGLYGNF 1010
++ K V F H ++ G L +G++ PL + P ++ G F
Sbjct: 2904 GLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGF 2963
Query: 1011 TAQVRFISDFSMSYEGF-----------------NITFSEYDLEPCE-EPEVPAYSIRKG 1052
+ FI + Y+ F + + S PC V Y G
Sbjct: 2964 S----FIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTVNG 3019
Query: 1053 LQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCV-AECGN 1100
F G CF G++L G + ITC + WSS P C CG+
Sbjct: 3020 TDFDCGKAARIQCFKGFKLLGLSEITCEADGQ--WSSGFPHCEHTSCGS 3066
Score = 86.7 bits (213), Expect = 4e-16
Identities = 120/535 (22%), Positives = 189/535 (35%), Gaps = 115/535 (21%)
Query: 98 GFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRLPNGIQQGSTFNL 157
GF+L SA T L D+ V A +A + C +P + NG +G+ ++
Sbjct: 2527 GFRLEGP--SALTCLET---GDWDVDAPSCNAIH-------CDSPQPIENGFVEGADYSY 2574
Query: 158 GDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACG----------GTLR 207
G + YSC GF + GHA+ TC + W +P+C D CG L+
Sbjct: 2575 GAIIIYSCFPGFQVAGHAMQTC-----EESGWSSSIPTCMPID-CGLPPHIDFGDCTKLK 2628
Query: 208 GQSGIIS-----------SPHFPSEYHNNADC-TWTILAELGDTIALVF-----IDFQLE 250
G +PH P YH A TW E T + F + +
Sbjct: 2629 DDQGYFEQEDDMMEVPYVTPHPP--YHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCN 2686
Query: 251 DGYDFL-------EVTGT-EGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQ 302
GY+ L + GT GS+ P +LR TS G+ + Q
Sbjct: 2687 PGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGS------AVQ 2740
Query: 303 YQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLG 362
Y K L ++L S + C P G GS++
Sbjct: 2741 YSCKPGHILAGSDLRLCLENRKWSGASPRCEA------ISCKKPNPVMNGSIKGSNYTYL 2794
Query: 363 SSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFP 422
S++ + C+ GY L G++R TC + W + P+C C + +G + +
Sbjct: 2795 STLYYECDPGYVLNGTERRTCQDDKN----WDEDEPICIPVDCSSPPVSANGQVRGDEYT 2850
Query: 423 IQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTS 482
Q + C E F LE + + +G G + + T
Sbjct: 2851 FQKEIEYTC----------------NEGFLLEGARSRVCLANGSWSGATPDCVPVRCATP 2894
Query: 483 VPDL---------------IVSTNHQMWLLF-------QTDGSGSSLGFKASYEEIEQGS 520
P L + H+ ++L Q+DG+ + A + +
Sbjct: 2895 -PQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGN-----WDAEIPLCKPVN 2948
Query: 521 CGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCV 575
CG P A+G G F HG ++++C P ++L G + C N WS P C+
Sbjct: 2949 CGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCL 3003
Score = 83.6 bits (205), Expect = 3e-15
Identities = 50/156 (32%), Positives = 71/156 (45%), Gaps = 8/156 (5%)
Query: 3088 YRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFG-IQNNSQ 3146
+ ++ CHP LVGS C +G WSG++ C + TC P+ G I +++
Sbjct: 398 FNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYC---RVRTCPHLRQPKHGHISCSTR 454
Query: 3147 GYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDL 3206
+T L C +GY L+GS TC N W G P CV HC + P + +
Sbjct: 455 EMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNC 514
Query: 3207 ---PSMGYTLIY-SCQEGFSLKGGSEHRTCKADGSW 3238
P+ T+ Y SC++GF L G E C G W
Sbjct: 515 GKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKW 550
Score = 82.4 bits (202), Expect = 7e-15
Identities = 50/156 (32%), Positives = 73/156 (46%), Gaps = 10/156 (6%)
Query: 2616 FQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLS- 2674
F A + C PG+ G +I C NG WS +S CR+ +C L P +GH +
Sbjct: 398 FNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESY--CRVRTCPHLRQPKHGHISCSTRE 455
Query: 2675 -VYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGT----PEPIVNGHING 2729
+Y T + +C+ GY L GS C N W G E RC+ HC T + I++ H G
Sbjct: 456 MLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCG 515
Query: 2730 ENYSYRGSVVY-QCNAGFRLIGMSVRI-CQQDHHWS 2763
+ + G++ Y C GF L G+ + C W+
Sbjct: 516 KQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWN 551
Score = 79.7 bits (195), Expect = 5e-14
Identities = 188/856 (21%), Positives = 293/856 (34%), Gaps = 130/856 (15%)
Query: 690 ECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCE 749
EC P P NG +GS++ + C G + GS+ C+ W+ A RCE
Sbjct: 2716 ECDLPTAPENGFLRFTETSMGSAVQYSCKPGHI-LAGSDLRLCLENRK---WSGASPRCE 2771
Query: 750 A-PCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRF-KTEVNYDTLE 807
A C +G+I + Y L E PGY + T R + + N+D E
Sbjct: 2772 AISCKKPNPVMNGSIKGSNYT--YLSTL----YYECDPGYVLNGTERRTCQDDKNWDEDE 2825
Query: 808 -VRDGRTYSAPLIGVYHGTQVPQFLIS-----TSNYLYLLFSTDKSHSDIGFQLRYETIT 861
+ S+P + + ++ T N +LL T
Sbjct: 2826 PICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPD 2885
Query: 862 LQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCE 921
C P NG G D+ VTF C GY L L C+ + W +P C+
Sbjct: 2886 CVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCK 2945
Query: 922 AL-CGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLI 980
+ CG L+ GFP+ + I H + F + H S L
Sbjct: 2946 PVNCG------PPEDLAHGFPNGFS-------FIHGGHIQYQCFPGYKLHGNSSRRCL-- 2990
Query: 981 TENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMS-------YEGFNIT-FS 1032
NGS++ R P+ YG +DF ++GF + S
Sbjct: 2991 -SNGSWSGSSPSCLPCRCSTPVIE--YGTVNG-----TDFDCGKAARIQCFKGFKLLGLS 3042
Query: 1033 EYDLEP----------CEE------PEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTAR 1076
E E CE P +P I + + + +T+SC GY ++G++
Sbjct: 3043 EITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKE-NVITYSCRSGYVIQGSSD 3101
Query: 1077 ITCLGGRRRLWSSPLPRCVA-ECGNSVTGTQGTLLSPNFPVNYNNNHECI--YSIQTQPG 1133
+ C + +WS P P C CG+ + C+ Y++ T
Sbjct: 3102 LICT--EKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTD 3159
Query: 1134 ------------KGIQLKARAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTS 1181
+ I + L E + G++ S S +E G T +
Sbjct: 3160 TFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAE--GYTFEGVN 3217
Query: 1182 SSLWLDFITDAENTSKGFELHFS--SFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCD 1239
S + + T +E FS S + C P +P+ G+ V + F S++ + C+
Sbjct: 3218 IS-----VCQLDGT---WEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFE-STIIYQCE 3268
Query: 1240 PGYSLRGSEELLCLSGERRTWDRPLPTCVAECGGT----VRGEVSGQVLSPGYPAPYEHN 1295
PGY L G+ E +C E R W + C T + G+ + + G Y N
Sbjct: 3269 PGYELEGNRERVC--QENRQWSGGVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCN 3326
Query: 1296 LNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTF 1355
+EA CT + H V P ++ E L +
Sbjct: 3327 RGYSLEGPSEAHCT-------ENGTWSHPVPLCKPNPCPVPFVIPE--NALLSEKEFYVD 3377
Query: 1356 NSVVLQFSTDFFTSKQGFAIQFSVSTAT---------SCNDPGIPQNGSRSGDSWEAGDS 1406
+V ++ F G T T SC P +N G ++ GD
Sbjct: 3378 QNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDM 3437
Query: 1407 TVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPN---YPE 1463
+ C GY L+G C +EN + SPP C A C G+ PN PE
Sbjct: 3438 ITYSCYSGYMLEGFLRSVC--LENGTW--TSPPICRAVCRFPCQN-GGICQRPNACSCPE 3492
Query: 1464 PYPPGKECDWKVTVSP 1479
+ G+ C+ + + P
Sbjct: 3493 GW-MGRLCEEPICILP 3507
Score = 73.2 bits (178), Expect = 4e-12
Identities = 102/465 (21%), Positives = 167/465 (35%), Gaps = 83/465 (17%)
Query: 129 ATYEVLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSAT 188
AT + +P C P +L NG+ +G + +V + C+ G+ L G LTC ++
Sbjct: 2882 ATPDCVPVR-CATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTC----QSDGN 2936
Query: 189 WDFPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQ 248
WD +P C+ + CG G + F H C F ++
Sbjct: 2937 WDAEIPLCKPVN-CGPPEDLAHGFPNGFSFIHGGHIQYQC---------------FPGYK 2980
Query: 249 LEDGYD--FLEVTGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVK 306
L L GSS PVI + T +G G +A+ Q
Sbjct: 2981 LHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIE-------YGTVNGTDFDCGKAARIQCF 3033
Query: 307 KQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPD-PGIPERGKRLGSDFRLGSSV 365
K +L G+ + + + Q +S H C P IP S ++ + +
Sbjct: 3034 KGFKLL--GLSEITCEADGQWSSGFPHCE----HTSCGSLPMIPNAFISETSSWK-ENVI 3086
Query: 366 QFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQY 425
++C GY +QGS + C + WS PVC C + + + T +
Sbjct: 3087 TYSCRSGYVIQGSSDLICTEKG----VWSQPYPVCEPLSCGSPPSVANAVATGEAHTYES 3142
Query: 426 DNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKT--------VLYI 477
+ C+ E + ++ DT T G+ ++ +
Sbjct: 3143 EVKLRCL----------------EGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPEN 3186
Query: 478 LTGTSVPDLIVSTNHQMWL--------------LFQTDGSGSSLGFKASYEEIEQGSCGD 523
+T V S N Q+ + + Q DG+ S E SCG
Sbjct: 3187 ITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEP---PFSDESCSPVSCGK 3243
Query: 524 PGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWS 568
P P +G GS++ T+ ++C+P +EL G + CQ+N QWS
Sbjct: 3244 PESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWS 3288
Score = 72.0 bits (175), Expect = 1e-11
Identities = 117/599 (19%), Positives = 204/599 (34%), Gaps = 90/599 (15%)
Query: 343 CPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRA 402
C PG PE G G + +G+ V F+C EGY L G +ITC++ + W+ P C+A
Sbjct: 1789 CKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGE----WNHLIPYCKA 1844
Query: 403 RMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGY-DTLT 461
C +G I F C T + LA + + +
Sbjct: 1845 VSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVK 1904
Query: 462 VGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSC 521
+ K +L LT S T + + + + S + +A C
Sbjct: 1905 CSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAP-PACHLVFC 1963
Query: 522 GDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCV-FSC-- 578
G+P G+ F +T+ + C+ + L G I C + +WS C+ SC
Sbjct: 1964 GEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDE 2023
Query: 579 --FFNFTSPSGV----------VLSPNYPEDYGNHLHC----VWLILARPESRIHLAFND 622
+ SP S Y + L C W + + +
Sbjct: 2024 PPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKW-VPPEGQDMPRCIAHF 2082
Query: 623 IDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNIT 682
+ P + +++ + A+ S + + ++ A++E +I
Sbjct: 2083 CEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTS--AKIECMRGGQWNPSPMSIQ 2140
Query: 683 FTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWN 742
R C +P +NG G + G+ +++ C++GF +G + TC E + W+
Sbjct: 2141 CIPVR---CGEPPSIMNGYASGSNYSFGAMVAYSCNKGFY-IKGEKKSTC---EATGQWS 2193
Query: 743 SAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN 802
S + C +SC + + G+ T F++EV
Sbjct: 2194 SPIPTCH-------------------------PVSCGEPPKVENGFLEHTTGRIFESEVR 2228
Query: 803 YDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITL 862
Y + G Y P F+ + + HS+ +
Sbjct: 2229 Y---QCNPG----------YKSVGSPVFVCQANRHW---------HSE-------SPLMC 2259
Query: 863 QSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWS-RALPSC 920
C P NG G +F VG+ V F C+ GY L C+ + +W+ ++ P C
Sbjct: 2260 VPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 2318
Score = 69.7 bits (169), Expect = 5e-11
Identities = 170/820 (20%), Positives = 274/820 (33%), Gaps = 197/820 (24%)
Query: 866 HC--LDPGIPV---NGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSC 920
HC + G+P NG +DFY G+ VT+ C++GY L + C N W+ PSC
Sbjct: 1684 HCERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSC 1743
Query: 921 ----EALCGGFIQ------GSSGTILSPGFPDFYPNNLNCTWII--------ETSHGKGV 962
E G G+ + P + + NC I E H G
Sbjct: 1744 LDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGE 1803
Query: 963 FFTFH---TFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISD 1019
+T TF + G+ QL G + +G + + + +S
Sbjct: 1804 IYTVGAEVTFSCQEGY----------------QLMGVTKITCLESGEWNHLIPYCKAVS- 1846
Query: 1020 FSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITC 1079
C +P +P + L F G +T+ C GY L G +C
Sbjct: 1847 -------------------CGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSC 1887
Query: 1080 LGGRRRLWSSPLPRC-VAECGNSVTGTQGTLLSPNFPVNYNNNHECI--YSIQTQ----- 1131
L WS P C +C + G + ++ C YS+Q
Sbjct: 1888 LANSS--WSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIEC 1945
Query: 1132 PGKGIQLKA----RAFELSEGDVLK--VYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLW 1185
GI +A E +K V GNN + R ++ E G TL +
Sbjct: 1946 TASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKE--GYTLAGLDT--- 2000
Query: 1186 LDFITDAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLR 1245
++ + D + + + S + D +P+ +++ G + C GYSL
Sbjct: 2001 IECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLF------GDIAFYYCSDGYSLA 2054
Query: 1246 GSEELLCLSGERRTWDRP----LPTCVA-------ECGGTVRGEVSGQVLSPGYPAPYEH 1294
+ +LLC + W P +P C+A ++ VS + G ++
Sbjct: 2055 DNSQLLC--NAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKC 2112
Query: 1295 NLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHST 1354
+ A+ C G + + I PV G ++G A + +
Sbjct: 2113 MEGFVLNTSAKIECMRG-------GQWNPSPMSIQCIPVRCGEPPSIMNGYA--SGSNYS 2163
Query: 1355 FNSVVLQFSTDFFTSKQGFAI------------QFSVSTAT----SCNDPGIPQNGSRSG 1398
F ++V ++ +GF I Q+S T SC +P +NG
Sbjct: 2164 FGAMVA------YSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEH 2217
Query: 1399 DSWEAGDSTV-FQCDPGYALQGSAEISCVKIENRFFWQPSPPTCI-APCGGDLTGPSGVI 1456
+ +S V +QC+PGY GS C NR + SP C+ CG +G +
Sbjct: 2218 TTGRIFESEVRYQCNPGYKSVGSPVFVCQ--ANRHWHSESPLMCVPLDCGKPPPIQNGFM 2275
Query: 1457 LSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIG-SF 1515
N+ E KV F GY+ L+G S
Sbjct: 2276 KGENF--------EVGSKVQ-------------FFCNEGYE-------------LVGDSS 2301
Query: 1516 YGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSIKNGTRVGSDLK 1575
+ Q G+ SN + + C +P ++N +
Sbjct: 2302 WTCQKSGKWNKKSNPKCMPAK---------------------CPEPPLLENQLVLKELTT 2340
Query: 1576 LGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVC 1615
VT+ C G+ ++G S L C+ WN+ PVC
Sbjct: 2341 EVGVVTFSCKEGHVLQGPSVLKCLPSQQ----WNDSFPVC 2376
Score = 67.8 bits (164), Expect = 2e-10
Identities = 67/270 (24%), Positives = 103/270 (38%), Gaps = 34/270 (12%)
Query: 2623 ICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIF 2682
IC+ GYY G + C A + I SC +P P H S G+T+
Sbjct: 306 ICEKGYYGKGLQY-ECTACPSGTYKPEGSPGGISSC--IPCPDENHT----SPPGSTS-- 356
Query: 2683 SCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHI--NGENYSYRGSVVY 2740
+C+ + S C HC +P NG+ N N + +
Sbjct: 357 ------------PEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGV 404
Query: 2741 QCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDS----YTVGAVV 2796
+C+ GF L+G S+ +C + WSG +C + +C H P H +S + Y +V
Sbjct: 405 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 464
Query: 2797 RYSCIGKRTLVGNSTRMCGLDGHWTGSLPHC---SGTSVGVCGDPGIPAHGIRLGDSFDP 2853
+C L G+ C + W G P C ++ + D I H +
Sbjct: 465 --ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPA-KF 521
Query: 2854 GTVMRFSCEAGHVLRGSSER-TCQANGSWS 2882
GT+ SC G +L G E C +G W+
Sbjct: 522 GTICYVSCRQGFILSGVKEMLRCTTSGKWN 551
Score = 65.1 bits (157), Expect = 1e-09
Identities = 67/298 (22%), Positives = 109/298 (36%), Gaps = 58/298 (19%)
Query: 2861 CEAGHVLRGSS-ERTCQANGSWSGSQPECGVISC---------GNPGTPSNARVVFSDGL 2910
CE G+ +G E T +G++ G+ SC PG+ S V
Sbjct: 307 CEKGYYGKGLQYECTACPSGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCV----- 361
Query: 2911 VFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGN--DF 2968
CREGY A+G C +++C P NG + N +
Sbjct: 362 ---------CREGYRASG----------------QTCELVHCPALKPPENGYFIQNTCNN 396
Query: 2969 RYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGS-- 3026
+N +C PG+ + S++ C + W+G++ C+ C +G + S
Sbjct: 397 HFNAACGVRCHPGFDLVGS--SIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTR 454
Query: 3027 DFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVP-----SRGRR 3081
+ ++ ++ AC EGY+L TC+GN W G P+C C +P S
Sbjct: 455 EMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNC 514
Query: 3082 EDRGFSYRSSVSFSCHPPLVLVGSPRRF-CQSDGTWSGTQPSCIDPTLTTCADPGVPQ 3138
+ + + SC +L G C + G W+ + C D PQ
Sbjct: 515 GKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWN------VGVQAAVCKDVEAPQ 566
Score = 64.7 bits (156), Expect = 2e-09
Identities = 55/214 (25%), Positives = 84/214 (39%), Gaps = 21/214 (9%)
Query: 2755 ICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYT--VGAVVRYSCIGKRTLVGNSTR 2812
+C++ + SG+T C LV C P + ++ A C LVG+S
Sbjct: 361 VCREGYRASGQT--CELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSII 418
Query: 2813 MCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDP--GTVMRFSCEAGHVLRGS 2870
+C +G W+GS +C V C P HG + + T +C+ G+ L GS
Sbjct: 419 LCLPNGLWSGSESYCR---VRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGS 475
Query: 2871 SERTCQANGSWSGSQPECGVISCGNPGTPSNARV----VFSDGLVFSSSIVYECREGYYA 2926
+ TCQ N W G +P C C P + + F + CR+G+
Sbjct: 476 DKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFIL 535
Query: 2927 TGLLSR-HCSVNGTW-------TGSDPECLVINC 2952
+G+ C+ +G W D E INC
Sbjct: 536 SGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINC 569
Score = 63.2 bits (152), Expect = 4e-09
Identities = 60/260 (23%), Positives = 105/260 (40%), Gaps = 35/260 (13%)
Query: 2417 PSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA---PYCSLPRA 2473
P G S + N+++P TS + V R+G++ +C +
Sbjct: 334 PGGISSCIPCPDENHTSPPGSTSPEDCVC----------REGYRASGQTCELVHCPALKP 383
Query: 2474 PLHGFILGQTSTQP-GGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCG 2532
P +G+ + T + C+ G+ LVG S+ +C P G LWS + C+ +C
Sbjct: 384 PENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCL--PNG--LWSGSESYCRVRTCP 439
Query: 2533 LPEAPKNGMVF--GKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVP 2590
PK+G + +E T + +C EGY L+ + T C W P+CV
Sbjct: 440 HLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLT--CQGNSQWDGPE--PRCVE 495
Query: 2591 VTC-----PDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTG-QRVIRCQANGKW 2644
C P IS + + +F + C G+ +G + ++RC +GKW
Sbjct: 496 RHCSTFQMPKDVIISPHN-----CGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKW 550
Query: 2645 SLGDSTPTCRIISCGELPIP 2664
++G C+ + ++ P
Sbjct: 551 NVGVQAAVCKDVEAPQINCP 570
Score = 60.8 bits (146), Expect = 2e-08
Identities = 33/93 (35%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 3157 RCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPSMGY--TLI 3214
RC G+ L GS+ CLPN WSG+ C C P H ++ M Y T +
Sbjct: 405 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISC-STREMLYKTTCL 463
Query: 3215 YSCQEGFSLKGGSEHRTCKADGSWTGKPPICLE 3247
+C EG+ L+G S+ TC+ + W G P C+E
Sbjct: 464 VACDEGYRLEG-SDKLTCQGNSQWDGPEPRCVE 495
Score = 56.2 bits (134), Expect = 5e-07
Identities = 103/484 (21%), Positives = 154/484 (31%), Gaps = 92/484 (19%)
Query: 138 TCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCR 197
+CG P L NG F G V Y CN G++L G + + C ++ +W+ PSC
Sbjct: 1689 SCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFC----TDNGSWNGVSPSCL 1744
Query: 198 ADDAC---------GGTLRGQSGIISS--PHFPSEYHNNAD---CTWTILAELGDTIALV 243
D C L I S P + + N A+ C E G + +
Sbjct: 1745 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEI 1804
Query: 244 F-----IDFQLEDGYDFLEVT------GTEGSSL--WFTGASLPAPVISSKNWL-RLHFT 289
+ + F ++GY + VT E + L + S P I + L FT
Sbjct: 1805 YTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFT 1864
Query: 290 SDGNHRQRGFSAQYQVKKQIELK-SRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGI 348
G Y+ K L + + + S V V C P
Sbjct: 1865 F-------GSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPV-------KCSSPEN 1910
Query: 349 PERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAH 408
GK + S S+ ++C+ GY LQG I C W P C C
Sbjct: 1911 INNGKYILSGLTYLSTASYSCDTGYSLQGPSIIEC----TASGIWDRAPPACHLVFCGEP 1966
Query: 409 LRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTL-TVGDGGQ 467
+IT NF + + +E G DT+ + DG
Sbjct: 1967 PAIKDAVITGNNFTFR-----------------NTVTYTCKEGYTLAGLDTIECLADGKW 2009
Query: 468 DGDQKTVLYILTGTS--VPDLIVSTNHQMW--LLFQTDGSGSSLGFKASYEEIEQGS--- 520
+ L + V T H+++ + F G SL + QG
Sbjct: 2010 SRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVP 2069
Query: 521 -------------CGDPGIPAYGRREG---SRFHHGDTLKFECQPAFELVGQKAITCQKN 564
C P +Y E ++F G + F+C F L I C +
Sbjct: 2070 PEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRG 2129
Query: 565 NQWS 568
QW+
Sbjct: 2130 GQWN 2133
Score = 53.5 bits (127), Expect = 4e-06
Identities = 61/280 (21%), Positives = 105/280 (37%), Gaps = 63/280 (22%)
Query: 343 CPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRA 402
C P PE G +GS + S++ + C GY+L+G++ C + WS +C+
Sbjct: 3241 CGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQ----WSGGVAICKE 3296
Query: 403 RMCDA---HLRGPSGI---ITSPN--------FPIQYDNNAHCVWIITALNPSKVIK--- 445
C+ L G + I T PN + ++ + AHC T +P + K
Sbjct: 3297 TRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNP 3356
Query: 446 ------------LAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQ 493
L+ +EF +++ ++ +G ++L G + I +
Sbjct: 3357 CPVPFVIPENALLSEKEFYVDQNV-SIKCREG----------FLLQGHGI---ITCNPDE 3402
Query: 494 MWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFEL 553
W QT + E+ SCG P G + +GD + + C + L
Sbjct: 3403 TWT--QTSA------------KCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYML 3448
Query: 554 VGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPN 593
G C +N W++ P C C F + G+ PN
Sbjct: 3449 EGFLRSVCLENGTWTS-PPICRAVCRFPCQN-GGICQRPN 3486
Score = 53.1 bits (126), Expect = 5e-06
Identities = 93/420 (22%), Positives = 154/420 (36%), Gaps = 86/420 (20%)
Query: 1058 GDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVA-ECGNSVTGTQGTLLSPNFPV 1116
G + C PG++L G CL + W+ PLP C CG G + +F
Sbjct: 1651 GSKVNLFCDPGFQLVGNPVQYCLNQGQ--WTQPLPHCERISCGVPPPLENGFHSADDFYA 1708
Query: 1117 NYNNNHECIYSIQTQPGKGIQLKARAFELSEG----------DVLKVYDGNNNSARLLGV 1166
++C G + +R F G DV + G++ S
Sbjct: 1709 GSTVTYQC------NNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCS------ 1756
Query: 1167 FSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDE 1226
H+ + V S S + D +N + E IKC+ PG P+ G+ E
Sbjct: 1757 -EHASCLNVD-GSYICSCVPPYTGDGKNCA----------EPIKCKAPGNPENGHS-SGE 1803
Query: 1227 GHFAGSSVSFSCDPGYSLRGSEELLCL-SGERRTWDRPLPTCVA-ECGGTV---RGEVSG 1281
+ G+ V+FSC GY L G ++ CL SGE W+ +P C A CG G +
Sbjct: 1804 IYTVGAEVTFSCQEGYQLMGVTKITCLESGE---WNHLIPYCKAVSCGKPAIPENGCIEE 1860
Query: 1282 QVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKE 1341
+ G Y N + E+ C + ++ H PV V
Sbjct: 1861 LAFTFGSKVTYRCNKGYTLAGDKESSC-------LANSSWSH------SPPVCEPVKCSS 1907
Query: 1342 LSGPALPKDLHS--TFNSVVLQFSTDFFTSKQGFAIQF-SVSTATS-------------- 1384
P+++++ S + ST ++ G+++Q S+ T+
Sbjct: 1908 ------PENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLV 1961
Query: 1385 -CNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIA 1443
C +P ++ +G+++ ++ + C GY L G I C+ W S C+A
Sbjct: 1962 FCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGK---WSRSDQQCLA 2018
Score = 44.7 bits (104), Expect = 0.002
Identities = 23/61 (37%), Positives = 30/61 (49%), Gaps = 5/61 (8%)
Query: 138 TCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCR 197
+CG P + N I +G + GD + YSC G+ LEG C + TW P P CR
Sbjct: 3415 SCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVC----LENGTWTSP-PICR 3469
Query: 198 A 198
A
Sbjct: 3470 A 3470
Score = 42.7 bits (99), Expect = 0.006
Identities = 81/444 (18%), Positives = 148/444 (33%), Gaps = 87/444 (19%)
Query: 517 EQGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGC-- 574
E+ SCG P G F+ G T+ ++C + L+G + C N W+ P C
Sbjct: 1686 ERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLD 1745
Query: 575 VFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVI 634
V C D H C+ + ++ V P
Sbjct: 1746 VDECAVG--------------SDCSEHASCL---------NVDGSYICSCVPP-----YT 1777
Query: 635 KDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHS--TGKRGFNITFTTFRHN--- 689
DG P+ GN P + SSG + + + S G + +T T +
Sbjct: 1778 GDGKNCAEPIKCKAPGN--PENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEW 1835
Query: 690 ----------ECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSV 739
C P +P NG + GS +++ C++G+ G + +C+
Sbjct: 1836 NHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYT-LAGDKESSCLANSS-- 1892
Query: 740 VWNSAVLRCE-APCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFK 798
W+ + CE C +G + G + SC GY + +
Sbjct: 1893 -WSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSC------DTGYSL-----QGP 1940
Query: 799 TEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLY---LLFSTDKSHSDIGFQL 855
+ + + D + L+ + +I+ +N+ + + ++ + ++ G
Sbjct: 1941 SIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGL-- 1998
Query: 856 RYETITLQSD-------------HCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDG 902
+TI +D C +P I + G + + C GY+L+D
Sbjct: 1999 --DTIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADN 2056
Query: 903 EPLECEPNFQW----SRALPSCEA 922
L C +W + +P C A
Sbjct: 2057 SQLLCNAQGKWVPPEGQDMPRCIA 2080
Score = 42.0 bits (97), Expect = 0.011
Identities = 17/47 (36%), Positives = 24/47 (51%)
Query: 547 CQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPN 593
C + L G +TCQ N+QW +P CV F P V++SP+
Sbjct: 466 CDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPH 512
Score = 41.6 bits (96), Expect = 0.014
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 124 AQGFHATYEVLPSHTCGNPGRLPNGIQ-QGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAG 182
+Q ++ ++ V C P + G+ S + G V+YSC GFFL G++ C
Sbjct: 2366 SQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLC--- 2422
Query: 183 SENSATWDFPLPSC 196
+ TW PLP C
Sbjct: 2423 -QPDGTWSSPLPEC 2435
Score = 40.8 bits (94), Expect = 0.024
Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 2/54 (3%)
Query: 1060 TLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPN 1113
T +C GYRLEG+ ++TC G + W P PRCV ++ + ++SP+
Sbjct: 461 TCLVACDEGYRLEGSDKLTCQGNSQ--WDGPEPRCVERHCSTFQMPKDVIISPH 512
Score = 40.4 bits (93), Expect = 0.031
Identities = 55/251 (21%), Positives = 90/251 (35%), Gaps = 39/251 (15%)
Query: 139 CGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRA 198
C P + + + G F++ +V SC G+ EG + C TW+ P +
Sbjct: 3181 CPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQL----DGTWEPPF----S 3232
Query: 199 DDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEV 258
D++C G+ SP + TI+ +Q E GY E+
Sbjct: 3233 DESCSPVSCGKP---ESPEHGFVVGSKYTFESTII-------------YQCEPGY---EL 3273
Query: 259 TGT-----EGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKS 313
G + + W G ++ L+ +D +R G + Y + L+
Sbjct: 3274 EGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEG 3333
Query: 314 RGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPG-IPERGKRLGSDFRLGSSVQFTCNEG 372
PS+ + + + N CP P IPE +F + +V C EG
Sbjct: 3334 ------PSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREG 3387
Query: 373 YDLQGSKRITC 383
+ LQG ITC
Sbjct: 3388 FLLQGHGIITC 3398
Score = 38.9 bits (89), Expect = 0.090
Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 4/99 (4%)
Query: 1908 SCPEPAVPSNG-VKTGERYLVNDVVSF-QCEPGYALQGHAHISCMPGTVRRWNYPPPLCI 1965
+CP P +G + R ++ C+ GY L+G ++C + +W+ P P C+
Sbjct: 437 TCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNS--QWDGPEPRCV 494
Query: 1966 AQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGF 2004
+ T + + VI+SP G P+ ++ GF
Sbjct: 495 ERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGF 533
Score = 36.2 bits (82), Expect = 0.58
Identities = 19/52 (36%), Positives = 26/52 (50%), Gaps = 5/52 (9%)
Query: 369 CNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPN 420
C+EGY L+GS ++TC S W P C R C + P +I SP+
Sbjct: 466 CDEGYRLEGSDKLTCQGNSQ----WDGPEPRCVERHCST-FQMPKDVIISPH 512
Score = 35.4 bits (80), Expect = 1.00
Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 892 SCDSGYTLSDGEPLECEPNFQWSRALPSC-EALCGGFIQGSSGTILSP 938
+CD GY L + L C+ N QW P C E C F Q I+SP
Sbjct: 465 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTF-QMPKDVIISP 511
Score = 35.4 bits (80), Expect = 1.00
Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 2/32 (6%)
Query: 1237 SCDPGYSLRGSEELLCLSGERRTWDRPLPTCV 1268
+CD GY L GS++L C + WD P P CV
Sbjct: 465 ACDEGYRLEGSDKLTCQGNSQ--WDGPEPRCV 494
Score = 34.3 bits (77), Expect = 2.2
Identities = 25/74 (33%), Positives = 30/74 (40%), Gaps = 11/74 (14%)
Query: 343 CPDPGIPERG----KRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRP 398
CP PE G + F V+ C+ G+DL GS I C+ WS
Sbjct: 378 CPALKPPENGYFIQNTCNNHFNAACGVR--CHPGFDLVGSSIILCLP----NGLWSGSES 431
Query: 399 VCRARMCDAHLRGP 412
CR R C HLR P
Sbjct: 432 YCRVRTC-PHLRQP 444
Score = 33.9 bits (76), Expect = 2.9
Identities = 20/69 (28%), Positives = 26/69 (37%), Gaps = 2/69 (2%)
Query: 508 GFKASYEEIEQGSCG--DPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNN 565
G++AS + E C P Y + H C P F+LVG I C N
Sbjct: 365 GYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNG 424
Query: 566 QWSAKKPGC 574
WS + C
Sbjct: 425 LWSGSESYC 433
Score = 33.9 bits (76), Expect = 2.9
Identities = 21/81 (25%), Positives = 32/81 (39%), Gaps = 6/81 (7%)
Query: 139 CGNPGRLP-NGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCR 197
C P +P N + F + V C GF L+GH ++TC+ TW C
Sbjct: 3357 CPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNP----DETWTQTSAKCE 3412
Query: 198 ADDACGGTLRGQSGIISSPHF 218
+CG ++ I H+
Sbjct: 3413 -KISCGPPAHVENAIARGVHY 3432
Score = 33.5 bits (75), Expect = 3.8
Identities = 16/50 (32%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Query: 1411 CDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPN 1460
CD GY L+GS +++C + W P C+ P VI+SP+
Sbjct: 466 CDEGYRLEGSDKLTC---QGNSQWDGPEPRCVERHCSTFQMPKDVIISPH 512
Score = 33.1 bits (74), Expect = 5.0
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 6/54 (11%)
Query: 164 SCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQSGIISSPH 217
+C+ G+ LEG LTC S+ WD P P C + C T + +I SPH
Sbjct: 465 ACDEGYRLEGSDKLTCQGNSQ----WDGPEPRC-VERHC-STFQMPKDVIISPH 512
Score = 33.1 bits (74), Expect = 5.0
Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 8/78 (10%)
Query: 1584 CHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQYVGSDGVVLSPNY--PQNYTS 1641
C GY +EG+ L+C G W+ P P C + V++SP+ Q
Sbjct: 466 CDEGYRLEGSDKLTC----QGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKF 521
Query: 1642 GQICLYFVTVPKDYVVFG 1659
G IC +V+ + +++ G
Sbjct: 522 GTIC--YVSCRQGFILSG 537
Score = 32.7 bits (73), Expect = 6.5
Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 3/59 (5%)
Query: 1197 KGFELHFSSFELIKCEDPGTPKFGYKVHD--EGHFAGSSVSFSCDPGYSLRGSEELLCL 1253
+G+ + EL+ C P+ GY + + HF ++ C PG+ L GS +LCL
Sbjct: 364 EGYRASGQTCELVHCPALKPPENGYFIQNTCNNHF-NAACGVRCHPGFDLVGSSIILCL 421
Score = 32.7 bits (73), Expect = 6.5
Identities = 15/30 (50%), Positives = 17/30 (56%), Gaps = 2/30 (6%)
Query: 2149 CLPGYQLTGHPVLTCQHGTNRNWDHPLPKC 2178
C GY+L G LTCQ N WD P P+C
Sbjct: 466 CDEGYRLEGSDKLTCQ--GNSQWDGPEPRC 493
>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
Length = 2489
Score = 282 bits (721), Expect = 5e-75
Identities = 313/1226 (25%), Positives = 457/1226 (37%), Gaps = 226/1226 (18%)
Query: 2121 QECPDPEPFANGIVRG-AGYNVGQSVTFECLPGYQLTGHPVLTC-QHGTNRNWDHPLPKC 2178
+ C P NG+V VG + + C G++L GH C G +W P C
Sbjct: 1002 KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 1061
Query: 2179 E-VPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPS----- 2232
+ +PCG T +NG S + + S V G G R L+ EPS
Sbjct: 1062 QRIPCGLPPTIANGDFISTNRENFHYGS---VVTYRCNPGSGGRKVFELVG-EPSIYCTS 1117
Query: 2233 -GDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPL 2291
D + IW GP AP+ +
Sbjct: 1118 NDDQVGIWSGP---APQCII---------------------------------------P 1135
Query: 2292 TKCPPPTILPNAEVVTENEE-FNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPI 2350
KC PP + N +V++N F++ ++V +RC PGF + G + C+ ++E P
Sbjct: 1136 NKCTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ--ALNKWEPELPS 1192
Query: 2351 CEVHC--PTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQY 2408
C C P + L + T PG F +C EP Y++
Sbjct: 1193 CSRVCQPPPDVLHAERTQRDKDNFSPGQ-EVFYSC------EPGYDLR------------ 1233
Query: 2409 DEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYC 2468
G + + G++S +AP C
Sbjct: 1234 ----------GAASMRCTPQGDWSP------------------------------AAPTC 1253
Query: 2469 SLPRAP------LHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEA 2522
+ L+G +L + Q G + F C+ G++L G S + C LW+ +
Sbjct: 1254 EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGME-SLWNSS 1312
Query: 2523 IPLCQALSCGLPEAPKNGMVFGKEYTV---GTKAMYSCS----EGYHLQAGAEATAECLD 2575
+P+C+ + C P NG GK V G Y+C G E+T C
Sbjct: 1313 VPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTS 1372
Query: 2576 ----TGLWSNRNVPPQCVPV---TCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGY 2628
G+WS+ P+C + PD + + + + L C P Y
Sbjct: 1373 DPQGNGVWSSP--APRCGILGHCQAPDHFLFAKLKTQTNA---SDFPIGTSLKYECRPEY 1427
Query: 2629 YYTGQRV-IRCQANGKWSLGDSTPTCRIISCGELPIPPNG--HRIGTLSVYGATAIFSCN 2685
Y G+ I C N WS C+ SC P P NG H I + V G+ +SC
Sbjct: 1428 Y--GRPFSITCLDNLVWS--SPKDVCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCT 1482
Query: 2686 SGYTLVGSRVRECMANGL---WSGSEVRCLAGHCGTPEPIVNGHI---NGENYSYRGSVV 2739
+G+ L+G EC+ +G WS C CG P I NG N EN+ Y V
Sbjct: 1483 TGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVT 1542
Query: 2740 YQCNAG------FRLIGMSVRICQQDHH----WSGKTPFCVLVSCGHPGSPPHSQMSGDS 2789
Y+CN G F L+G C + WSG P C++ + P + + + D+
Sbjct: 1543 YRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDN 1602
Query: 2790 ---YTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIR 2846
+++ VV + C + G C W LP CS VC P HG
Sbjct: 1603 RSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSR----VCQPPPEILHGEH 1658
Query: 2847 LG---DSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGN-PGTPSNA 2902
D+F PG + +SCE G+ LRG++ C G WS P C V SC + G +
Sbjct: 1659 TPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHG 1718
Query: 2903 RVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNG---TWTGSDPECLVINCGDPGIPA 2959
RV+F L + + + C EG+ G HC + G W S P C I C +P
Sbjct: 1719 RVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAIL 1778
Query: 2960 NGLRLG---NDFRYNKTVTYQCVP----GYMMESHRVSVLSCTKD----RTWNGTKPVC- 3007
NG G D Y K ++Y C P G S + CT D W+ P C
Sbjct: 1779 NGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCE 1838
Query: 3008 ---KALMCKPPPLIPNGK----VVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTG 3060
+A CK P P + +F G+S+ Y C GY + ++ +C N W+
Sbjct: 1839 LSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSI-SCLENLVWSS 1897
Query: 3061 ELPQCFPVFCGDPGVPSRGR-REDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDG---TW 3116
C CG P P G + + S+V++SC+ L+GSP C G TW
Sbjct: 1898 VEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW 1957
Query: 3117 SGTQPSCIDPTLTTCADPGVPQFG--IQNNSQGYQVGSTVLFRCQKG------YLLQGST 3168
P C + +C P G NN + G+ V ++C G + L G
Sbjct: 1958 DKKAPIC---EIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGER 2014
Query: 3169 TRTCLPN----LTWSGTPPDCV-PHHCRQPETPTHANV-GALDLPSMGYTLIYSCQEGFS 3222
+ C WS PP C+ + C PE V G ++ + + CQ GF
Sbjct: 2015 SIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFV 2074
Query: 3223 LKGGSEHRTCKADGSWTGKPPICLEV 3248
+ GS C+ +G W K P C V
Sbjct: 2075 MV-GSHTVQCQTNGRWGPKLPHCSRV 2099
Score = 281 bits (718), Expect = 1e-74
Identities = 473/2021 (23%), Positives = 717/2021 (35%), Gaps = 383/2021 (18%)
Query: 1384 SCNDPGIPQNGS-RSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCI 1442
SC P P NG + G + C G+ L G + C+ N W PP C
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
Query: 1443 A-PCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHI 1501
PCG T +G +S N E + G ++ +P VF + EP ++
Sbjct: 613 RIPCGLPPTIANGDFISTNR-ENFHYGSVVTYRC--NPGSGGRKVFELVG-EPS---IYC 665
Query: 1502 YDGRDSLSPLIGSFYGSQLP----------GRIESSSNSLFLAFRSDASVSNAGFVIDYT 1551
D + G +P G + S + SLF GFV+
Sbjct: 666 TSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVM--- 722
Query: 1552 ENPRES------------------CFDPGSIKNGTRVGSD---LKLGSSVTYYCHGGYEV 1590
+ PR C P + + R D G V Y C GY++
Sbjct: 723 KGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDL 782
Query: 1591 EGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQYVGS--DGVVLSP-NYPQNYTSGQICLY 1647
G +++ C P G W+ P C ++G +G VL P N +C
Sbjct: 783 RGAASMRCT--PQGD--WSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDE 838
Query: 1648 FVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLI 1707
+ + A + N V V + S + +G HTG+ L + + +
Sbjct: 839 GFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIP-NGRHTGKPLEVFPFGKT-V 896
Query: 1708 KFSAKGLAPARG--FHFVYQAVPR-TSATQCSSV---PEPRYG----------------- 1744
++ P RG F + ++ R TS Q + V P PR G
Sbjct: 897 NYTCDP-HPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLK 955
Query: 1745 -KRLGSDFSVGAIVRFECNSGYALQGSP-EIECLPVPGALAQWNVSAPTCVVPCGGNLTE 1802
+ SDF +G +++EC Y G P I CL W+ C
Sbjct: 956 TQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDN----LVWSSPKDVC---------- 999
Query: 1803 RRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTM 1862
+R + +P P+P ++ + IQV S +
Sbjct: 1000 KRKSCKTP--PDPVNGMVHVI----------TDIQVGSRI-------------------- 1027
Query: 1863 LGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNG--VK 1920
++S TT L+ +S + L S +AA + + C P +NG +
Sbjct: 1028 --NYSCTTGHRLIGHSSAECIL------SGNAAHWSTKPPICQRIPCGLPPTIANGDFIS 1079
Query: 1921 TG-ERYLVNDVVSFQCEPG------YALQGHAHISCMPGT--VRRWNYPPPLCIAQCGGT 1971
T E + VV+++C PG + L G I C V W+ P P CI T
Sbjct: 1080 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 1139
Query: 1972 VEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYET 2031
+E IL + N + + F +P + GP
Sbjct: 1140 PPNVENGILVSDNRSLFSLN-----------------EVVEFRCQPGF----VMKGPRRV 1178
Query: 2032 SRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSFLRGFDL 2091
ELPS V H++ +Q Q++ YS + G+DL
Sbjct: 1179 KCQALNKWEPELPSCSRVCQPPPDV-LHAERTQRDKDNFSPGQEVFYSCE-----PGYDL 1232
Query: 2092 SELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRG-----AGYNVGQSVT 2146
TP D P E++ C D F ++ G +G V
Sbjct: 1233 RGAASMRCTPQ------GDWSPAAPTCEVKSCDD---FMGQLLNGRVLFPVNLQLGAKVD 1283
Query: 2147 FECLPGYQLTGHPVLTCQ-HGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSPYSSS 2205
F C G+QL G C G W+ +P CE ++ P P +
Sbjct: 1284 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE------------QIFCPSPPVIPNGR 1331
Query: 2206 QDCVWLITVPIGHGVRLNLS-----------------LLQTEPSGDFITIWDGPQQTAPR 2248
L P G V ++P G+ +W P APR
Sbjct: 1332 HTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGN--GVWSSP---APR 1386
Query: 2249 LGVFTRSMAK--------KTVQSSSNQVL---LKFH-RDAATGGIFAIAFS-----AYPL 2291
G+ A KT ++S+ + LK+ R G F+I + P
Sbjct: 1387 CGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPK 1446
Query: 2292 TKC-------PPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKL-GTYLQ 2343
C PP + V+T+ +G + Y C G L+G+ C L G
Sbjct: 1447 DVCKRKSCKTPPDPVNGMVHVITD---IQVGSRINYSCTTGHRLIGHSSAECILSGNTAH 1503
Query: 2344 FEGPPPICEVHCPTNELLTDSTGVILSQS----YPGSYPQFQTCSWLVRVEPDYNISLTV 2399
+ PPIC+ P T + G +S + + GS ++ C+ R + +
Sbjct: 1504 WSTKPPICQ-RIPCGLPPTIANGDFISTNRENFHYGSVVTYR-CNLGSRGRKVFELVGEP 1561
Query: 2400 EYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYL------------- 2446
+ + D+ I+ GP+ Q + + I+ S + S++
Sbjct: 1562 SIYCTSND-DQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGF 1620
Query: 2447 -----RWSSDHAYNRKGFKIRYSAPYCSLPRAPLHGFILG--QTSTQPGGSIHFGCNAGY 2499
R A N+ ++ + C P LHG Q + PG + + C GY
Sbjct: 1621 VMKGPRRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGY 1680
Query: 2500 RLVGHSMAICTRHPQGYHLWSEAIPLCQALSCG--LPEAPKNGMVFGKEYTVGTKAMYSC 2557
L G + CT PQG WS P C SC L + P ++F +G K + C
Sbjct: 1681 DLRGAASLHCT--PQGD--WSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVC 1736
Query: 2558 SEGYHLQAGAEATAECLDTG---LWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQY 2614
EG+ L+ + + C+ G LW+N P C + CP+ +I +GR
Sbjct: 1737 DEGFRLKGSS--VSHCVLVGMRSLWNNS--VPVCEHIFCPNPPAIL--NGRHTGTPSGDI 1790
Query: 2615 QFQAQLMLICDPG------YYYTGQRVIRCQA----NGKWSLGDSTPTCRI-ISCGELPI 2663
+ ++ CDP + G+ IRC + NG WS P C + + G
Sbjct: 1791 PYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWS--SPAPRCELSVRAGHCKT 1848
Query: 2664 PPN-GHRIGTLSV------YGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHC 2716
P T+ + G + + C GY + C+ N +WS E C C
Sbjct: 1849 PEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSI-SCLENLVWSSVEDNCRRKSC 1907
Query: 2717 GTPEPIVNG--HINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHH---WSGKTPFCVL 2771
G P NG HIN + + +V Y CN GFRLIG C + W K P C +
Sbjct: 1908 GPPPEPFNGMVHINTDT-QFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEI 1966
Query: 2772 VSCGHPGSPPHSQMSGDSYTV-------GAVVRYSCI----GKRT--LVGNSTRMCGLD- 2817
+SC PP + +GD Y+ G VV Y C G++ LVG + C
Sbjct: 1967 ISC----EPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKD 2022
Query: 2818 ---GHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDS---FDPGTVMRFSCEAGHVLRGSS 2871
G W+ P C T+ C P + + IR+ + F ++RF C+ G V+ GS
Sbjct: 2023 DQVGVWSSPPPRCISTNK--CTAPEVE-NAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSH 2079
Query: 2872 ERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFS--SSIVYECREGYYATGL 2929
CQ NG W P C + C P + S FS + Y C Y G
Sbjct: 2080 TVQCQTNGRWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGA 2138
Query: 2930 LSRHCSVNGTWTGSDPECLVINCGD--PGIPANGLRLGNDFRYNKTVTYQCVPGYMMESH 2987
S HC+ G W+ P C V +C D +P + L + + V++ C G+ ++
Sbjct: 2139 ASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGR 2198
Query: 2988 RVS--VLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGS---DFMWGSSVTYAC---- 3038
S VL+ K WN + PVC+ + C PP I NG+ G+ D +G ++YAC
Sbjct: 2199 SASHCVLAGMK-ALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHP 2257
Query: 3039 -------LEGYQLSLPAVFTCEGNGSWTGELPQC---FPVFCGDPGVPSRGRREDRGFSY 3088
L G + S+ +GNG W+ P+C P C P G S
Sbjct: 2258 DRGMTFNLIG-ESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSL 2316
Query: 3089 R---SSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNN- 3144
++S+ C P +LVG FC G WS C + C+ P + GI
Sbjct: 2317 YLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKE---VNCSFP-LFMNGISKEL 2372
Query: 3145 --SQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPP 3183
+ Y G V +C+ GY L+GS C + W PP
Sbjct: 2373 EMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWD--PP 2411
Score = 278 bits (712), Expect = 5e-74
Identities = 319/1227 (25%), Positives = 455/1227 (37%), Gaps = 231/1227 (18%)
Query: 2121 QECPDPEPFANGIVRGA-GYNVGQSVTFECLPGYQLTGHPVLTCQ-HGTNRNWDHPLPKC 2178
+ C +P NG+V G G + + C GY+L G TC G WD+ P C
Sbjct: 102 KSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 161
Query: 2179 E-VPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPS----- 2232
+ +PCG T +NG S + + S V G G R L+ EPS
Sbjct: 162 DRIPCGLPPTITNGDFISTNRENFHYGS---VVTYRCNPGSGGRKVFELVG-EPSIYCTS 217
Query: 2233 -GDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPL 2291
D + IW GP AP+ +
Sbjct: 218 NDDQVGIWSGP---APQCII---------------------------------------P 235
Query: 2292 TKCPPPTILPNAEVVTENEE-FNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPI 2350
KC PP + N +V++N F++ ++V +RC PGF + G + C+ ++E P
Sbjct: 236 NKCTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ--ALNKWEPELPS 292
Query: 2351 CEVHC--PTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQY 2408
C C P + L + T PG F +C EP Y++
Sbjct: 293 CSRVCQPPPDVLHAERTQRDKDNFSPGQ-EVFYSC------EPGYDLR------------ 333
Query: 2409 DEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYC 2468
G + + G++S +AP C
Sbjct: 334 ----------GAASMRCTPQGDWSP------------------------------AAPTC 353
Query: 2469 SLPRAP------LHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEA 2522
+ L+G +L + Q G + F C+ G++L G S + C LW+ +
Sbjct: 354 EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGME-SLWNSS 412
Query: 2523 IPLCQALSCGLPEAPKNGMVFGKEYTV---GTKAMYSCS----EGYHLQAGAEATAECLD 2575
+P+C+ + C P NG GK V G Y+C G E+T C
Sbjct: 413 VPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTS 472
Query: 2576 ----TGLWSNRNVPPQCVPV---TCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGY 2628
G+WS+ P+C + PD + + + + L C P Y
Sbjct: 473 DPQGNGVWSSP--APRCGILGHCQAPDHFLFAKLKTQTNA---SDFPIGTSLKYECRPEY 527
Query: 2629 YYTGQRV-IRCQANGKWSLGDSTPTCRIISCGELPIPPNG--HRIGTLSVYGATAIFSCN 2685
Y G+ I C N WS C+ SC P P NG H I + V G+ +SC
Sbjct: 528 Y--GRPFSITCLDNLVWS--SPKDVCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCT 582
Query: 2686 SGYTLVGSRVRECMANGL---WSGSEVRCLAGHCGTPEPIVNGHI---NGENYSYRGSVV 2739
+G+ L+G EC+ +G WS C CG P I NG N EN+ Y V
Sbjct: 583 TGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVT 642
Query: 2740 YQCNAG------FRLIGMSVRICQQDHH----WSGKTPFCVLVSCGHPGSPPHSQMSGDS 2789
Y+CN G F L+G C + WSG P C++ + P + + + D+
Sbjct: 643 YRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDN 702
Query: 2790 ---YTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIR 2846
+++ VV + C + G C W LP CS VC P H R
Sbjct: 703 RSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSR----VCQPPPDVLHAER 758
Query: 2847 LG---DSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGN-PGTPSNA 2902
D+F PG + +SCE G+ LRG++ C G WS + P C V SC + G N
Sbjct: 759 TQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNG 818
Query: 2903 RVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNG---TWTGSDPECLVINCGDPGIPA 2959
RV+F L + + + C EG+ G + +C + G W S P C I C P +
Sbjct: 819 RVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIP 878
Query: 2960 NGLRLGND---FRYNKTVTYQCVP----GYMMESHRVSVLSCTKD----RTWNGTKPVCK 3008
NG G F + KTV Y C P G + S + CT D W+ P C
Sbjct: 879 NGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCG 938
Query: 3009 AL-MCKPPPLIPNGKVV----GSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELP 3063
L C+ P K+ SDF G+S+ Y C Y P TC N W+
Sbjct: 939 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKD 997
Query: 3064 QCFPVFCGDPGVPSRGR-REDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGT---WSGT 3119
C C P P G S +++SC L+G C G WS
Sbjct: 998 VCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTK 1057
Query: 3120 QPSCIDPTLTTCADPGVPQFG--IQNNSQGYQVGSTVLFRCQKG------YLLQGSTTRT 3171
P C C P G I N + + GS V +RC G + L G +
Sbjct: 1058 PPIC---QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIY 1114
Query: 3172 CLPN----LTWSGTPPDC-VPHHCRQPETPTHANVGAL-----DLPSMGYTLIYSCQEGF 3221
C N WSG P C +P+ C TP + G L L S+ + + CQ GF
Sbjct: 1115 CTSNDDQVGIWSGPAPQCIIPNKC----TPPNVENGILVSDNRSLFSLNEVVEFRCQPGF 1170
Query: 3222 SLKGGSEHRTCKADGSWTGKPPICLEV 3248
+KG + C+A W + P C V
Sbjct: 1171 VMKGPRRVK-CQALNKWEPELPSCSRV 1196
Score = 273 bits (697), Expect = 3e-72
Identities = 316/1227 (25%), Positives = 452/1227 (36%), Gaps = 231/1227 (18%)
Query: 2121 QECPDPEPFANGIVRG-AGYNVGQSVTFECLPGYQLTGHPVLTC-QHGTNRNWDHPLPKC 2178
+ C P NG+V VG + + C G++L GH C G +W P C
Sbjct: 552 KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Query: 2179 E-VPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPS----- 2232
+ +PCG T +NG S + + S V G G R L+ EPS
Sbjct: 612 QRIPCGLPPTIANGDFISTNRENFHYGS---VVTYRCNPGSGGRKVFELVG-EPSIYCTS 667
Query: 2233 -GDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPL 2291
D + IW GP AP+ +
Sbjct: 668 NDDQVGIWSGP---APQCII---------------------------------------P 685
Query: 2292 TKCPPPTILPNAEVVTENEE-FNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPI 2350
KC PP + N +V++N F++ ++V +RC PGF + G + C+ ++E P
Sbjct: 686 NKCTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ--ALNKWEPELPS 742
Query: 2351 CEVHC--PTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQY 2408
C C P + L + T PG F +C EP Y++
Sbjct: 743 CSRVCQPPPDVLHAERTQRDKDNFSPGQ-EVFYSC------EPGYDLR------------ 783
Query: 2409 DEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYC 2468
G + + G++S +AP C
Sbjct: 784 ----------GAASMRCTPQGDWSP------------------------------AAPTC 803
Query: 2469 SLPRAP------LHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEA 2522
+ L+G +L + Q G + F C+ G++L G S + C LW+ +
Sbjct: 804 EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGME-SLWNSS 862
Query: 2523 IPLCQALSCGLPEAPKNGMVFGKEYTV---GTKAMYSCS----EGYHLQAGAEATAECLD 2575
+P+C+ + C P NG GK V G Y+C G E+T C
Sbjct: 863 VPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTS 922
Query: 2576 ----TGLWSNRNVPPQCVPV---TCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGY 2628
G+WS+ P+C + PD + + + + L C P Y
Sbjct: 923 DPQGNGVWSSP--APRCGILGHCQAPDHFLFAKLKTQTNA---SDFPIGTSLKYECRPEY 977
Query: 2629 YYTGQRV-IRCQANGKWSLGDSTPTCRIISCGELPIPPNG--HRIGTLSVYGATAIFSCN 2685
Y G+ I C N WS C+ SC P P NG H I + V G+ +SC
Sbjct: 978 Y--GRPFSITCLDNLVWS--SPKDVCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCT 1032
Query: 2686 SGYTLVGSRVRECMANGL---WSGSEVRCLAGHCGTPEPIVNGHI---NGENYSYRGSVV 2739
+G+ L+G EC+ +G WS C CG P I NG N EN+ Y V
Sbjct: 1033 TGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVT 1092
Query: 2740 YQCNAG------FRLIGMSVRICQQDHH----WSGKTPFCVLVSCGHPGSPPHSQMSGDS 2789
Y+CN G F L+G C + WSG P C++ + P + + + D+
Sbjct: 1093 YRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDN 1152
Query: 2790 ---YTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIR 2846
+++ VV + C + G C W LP CS VC P H R
Sbjct: 1153 RSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSR----VCQPPPDVLHAER 1208
Query: 2847 LG---DSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGN-PGTPSNA 2902
D+F PG + +SCE G+ LRG++ C G WS + P C V SC + G N
Sbjct: 1209 TQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNG 1268
Query: 2903 RVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNG---TWTGSDPECLVINCGDPGIPA 2959
RV+F L + + + C EG+ G + +C + G W S P C I C P +
Sbjct: 1269 RVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIP 1328
Query: 2960 NGLRLGND---FRYNKTVTYQCVP----GYMMESHRVSVLSCTKD----RTWNGTKPVCK 3008
NG G F + K V Y C P G + S + CT D W+ P C
Sbjct: 1329 NGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCG 1388
Query: 3009 AL-MCKPPPLIPNGKVV----GSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELP 3063
L C+ P K+ SDF G+S+ Y C Y P TC N W+
Sbjct: 1389 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKD 1447
Query: 3064 QCFPVFCGDPGVPSRGR-REDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGT---WSGT 3119
C C P P G S +++SC L+G C G WS
Sbjct: 1448 VCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTK 1507
Query: 3120 QPSCIDPTLTTCADPGVPQFG--IQNNSQGYQVGSTVLFRCQKG------YLLQGSTTRT 3171
P C C P G I N + + GS V +RC G + L G +
Sbjct: 1508 PPIC---QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIY 1564
Query: 3172 CLPN----LTWSGTPPDC-VPHHCRQPETPTHANVGAL-----DLPSMGYTLIYSCQEGF 3221
C N WSG P C +P+ C TP + G L L S+ + + CQ GF
Sbjct: 1565 CTSNDDQVGIWSGPAPQCIIPNKC----TPPNVENGILVSDNRSLFSLNEVVEFRCQPGF 1620
Query: 3222 SLKGGSEHRTCKADGSWTGKPPICLEV 3248
+KG + C+A W + P C V
Sbjct: 1621 VMKGPRRVK-CQALNKWEPELPSCSRV 1646
Score = 268 bits (685), Expect = 7e-71
Identities = 283/1093 (25%), Positives = 416/1093 (38%), Gaps = 211/1093 (19%)
Query: 2121 QECPDPEPFANGIVRG-AGYNVGQSVTFECLPGYQLTGHPVLTC-QHGTNRNWDHPLPKC 2178
+ C P NG+V VG + + C G++L GH C G +W P C
Sbjct: 1452 KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPIC 1511
Query: 2179 E-VPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVR-LNLSLLQTEPS---- 2232
+ +PCG T +NG S + + S ++T G R + L EPS
Sbjct: 1512 QRIPCGLPPTIANGDFISTNRENFHYGS-----VVTYRCNLGSRGRKVFELVGEPSIYCT 1566
Query: 2233 --GDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYP 2290
D + IW GP AP+ +
Sbjct: 1567 SNDDQVGIWSGP---APQCII--------------------------------------- 1584
Query: 2291 LTKCPPPTILPNAEVVTENEE-FNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPP 2349
KC PP + N +V++N F++ ++V +RC PGF + G + C+ ++E P
Sbjct: 1585 PNKCTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ--ALNKWEPELP 1641
Query: 2350 ICEVHC-PTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQY 2408
C C P E+L ++ F +C EP Y++
Sbjct: 1642 SCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSC------EPGYDLR------------ 1683
Query: 2409 DEFEIFDGPSGQSPLLKALSGNYS--APLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAP 2466
G + L G++S AP S +
Sbjct: 1684 ----------GAASLHCTPQGDWSPEAPRCAVKSCDDF---------------------- 1711
Query: 2467 YCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLC 2526
L + P HG +L + Q G + F C+ G+RL G S++ C LW+ ++P+C
Sbjct: 1712 ---LGQLP-HGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMR-SLWNNSVPVC 1766
Query: 2527 QALSCGLPEAPKNGMVFGK---EYTVGTKAMYSCS----EGYHLQAGAEATAECLD---- 2575
+ + C P A NG G + G + Y+C G E+T C
Sbjct: 1767 EHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHG 1826
Query: 2576 TGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRL------------IFETQYQFQAQLMLI 2623
G+WS+ P+C +SV G + I + ++ L
Sbjct: 1827 NGVWSSP--APRC---------ELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYE 1875
Query: 2624 CDPGYYYTGQRV-IRCQANGKWSLGDSTPTCRIISCGELPIPPNGH-RIGTLSVYGATAI 2681
C PGY+ G+ I C N WS + CR SCG P P NG I T + +G+T
Sbjct: 1876 CRPGYF--GKMFSISCLENLVWSSVEDN--CRRKSCGPPPEPFNGMVHINTDTQFGSTVN 1931
Query: 2682 FSCNSGYTLVGSRVRECMANG---LWSGSEVRCLAGHCGTPEPIVNGHINGENYS--YRG 2736
+SCN G+ L+GS C+ +G W C C P I NG N + + G
Sbjct: 1932 YSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNG 1991
Query: 2737 SVV-YQCNAG------FRLIGMSVRIC----QQDHHWSGKTPFCVLVS-CGHPGSPPHSQ 2784
+VV YQC+ G F L+G C Q WS P C+ + C P +
Sbjct: 1992 TVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIR 2051
Query: 2785 MSGDS--YTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPA 2842
+ G+ +T+ ++R+ C +VG+ T C +G W LPHCS VC P
Sbjct: 2052 VPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSR----VCQPPPEIL 2107
Query: 2843 HG---IRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGN-PGT 2898
HG + D+F PG + +SCE + LRG++ C G WS P C V SC + G
Sbjct: 2108 HGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQ 2167
Query: 2899 PSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNG---TWTGSDPECLVINCGDP 2955
+ RV+ L + + + C EG+ G + HC + G W S P C I C +P
Sbjct: 2168 LPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNP 2227
Query: 2956 GIPANGLRLG---NDFRYNKTVTYQCVP----GYMMESHRVSVLSCTKD----RTWNGTK 3004
NG G D Y K ++Y C G S + CT D W+
Sbjct: 2228 PAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPA 2287
Query: 3005 PVCKALM---CKPPPLIPNGKVVG---SDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSW 3058
P C+ + C PP I NG +G S ++ G +++Y C GY L C G W
Sbjct: 2288 PRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIW 2347
Query: 3059 TGELPQCFPVFCGDP----GVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDG 3114
+ C V C P G+ S+ + + Y V+ C L GSP CQ+D
Sbjct: 2348 SQLDHYCKEVNCSFPLFMNGI-SKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADD 2406
Query: 3115 TWSGTQPSCIDPT 3127
W C T
Sbjct: 2407 RWDPPLAKCTSRT 2419
Score = 268 bits (684), Expect = 9e-71
Identities = 306/1228 (24%), Positives = 445/1228 (36%), Gaps = 217/1228 (17%)
Query: 2139 YNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCG--------------- 2183
+++ + V F C PG+ + G + CQ W+ LP C C
Sbjct: 256 FSLNEVVEFRCQPGFVMKGPRRVKCQ--ALNKWEPELPSCSRVCQPPPDVLHAERTQRDK 313
Query: 2184 GNITSSNGTVYS--PGFPSPYSSSQDCV----WLITVPIGHGVRLNLSLLQTEPSGDFIT 2237
N + YS PG+ ++S C W P + + DF+
Sbjct: 314 DNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPT----------CEVKSCDDFMG 363
Query: 2238 IWDGPQQTAP---RLGVFTRSMAKKTVQ---SSSNQVLLKFHRDAATGGIFAIAFSAYPL 2291
+ P +LG + + Q SS++ +L G+ ++ S+ P+
Sbjct: 364 QLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVL--------AGMESLWNSSVPV 415
Query: 2292 TK---CPPPTILPNAEVVTEN-EEFNIGDIVRYRCLP------GFTLVGNEILTCKLGTY 2341
+ CP P ++PN + E F G V Y C P F L+G + C
Sbjct: 416 CEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQ 475
Query: 2342 LQ--FEGPPPICEV--HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISL 2397
+ P P C + HC PD+
Sbjct: 476 GNGVWSSPAPRCGILGHCQA---------------------------------PDH---- 498
Query: 2398 TVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRK 2457
FL K + D P G S + Y P +T N V WSS ++
Sbjct: 499 ----FLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLV---WSSPKDVCKR 551
Query: 2458 GFKIRYSAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYH 2517
C P P++G + T Q G I++ C G+RL+GHS A C H
Sbjct: 552 --------KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAH 603
Query: 2518 LWSEAIPLCQALSCGLPEAPKNGMVFG---KEYTVGTKAMYSCSEG------YHL--QAG 2566
WS P+CQ + CGLP NG + + G+ Y C+ G + L +
Sbjct: 604 -WSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPS 662
Query: 2567 AEATAECLDTGLWSNRNVPPQC-VPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICD 2625
T+ G+WS PQC +P C + +VE+G + + + C
Sbjct: 663 IYCTSNDDQVGIWS--GPAPQCIIPNKC---TPPNVENGILVSDNRSLFSLNEVVEFRCQ 717
Query: 2626 PGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLS-----VYGATA 2680
PG+ G R ++CQA KW P+C + P P H T G
Sbjct: 718 PGFVMKGPRRVKCQALNKWE--PELPSCSRVC---QPPPDVLHAERTQRDKDNFSPGQEV 772
Query: 2681 IFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGE-----NYSYR 2735
+SC GY L G+ C G WS + C C + + +NG N
Sbjct: 773 FYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSC---DDFMGQLLNGRVLFPVNLQLG 829
Query: 2736 GSVVYQCNAGFRLIGMSVRIC---QQDHHWSGKTPFCVLVSCGHPGSPPHSQMSG---DS 2789
V + C+ GF+L G S C + W+ P C + C P P+ + +G +
Sbjct: 830 AKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEV 889
Query: 2790 YTVGAVVRYSCI------GKRTLVGNSTRMCGLD----GHWTGSLPHCSGTSVGVCGDPG 2839
+ G V Y+C L+G ST C D G W+ P C G+ G
Sbjct: 890 FPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC-----GILGHCQ 944
Query: 2840 IPAHGI-------RLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVIS 2892
P H + F GT +++ C + R S TC N WS + C S
Sbjct: 945 APDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFS-ITCLDNLVWSSPKDVCKRKS 1003
Query: 2893 CGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGT---WTGSDPECLV 2949
C P P N V + S I Y C G+ G S C ++G W+ P C
Sbjct: 1004 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQR 1063
Query: 2950 INCGDPGIPANGLRLG---NDFRYNKTVTYQCVPG----YMMESHRVSVLSCTKD----R 2998
I CG P ANG + +F Y VTY+C PG + E + CT +
Sbjct: 1064 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 1123
Query: 2999 TWNGTKPVCKALMCKPPPLIPNGKVVGSD---FMWGSSVTYACLEGYQLSLPAVFTCEGN 3055
W+G P C PP + NG +V + F V + C G+ + P C+
Sbjct: 1124 IWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 1183
Query: 3056 GSWTGELPQCFPVFCGDPGV--PSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSD 3113
W ELP C V P V R +R+ FS V +SC P L G+ C
Sbjct: 1184 NKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ 1243
Query: 3114 GTWSGTQPSCIDPTLTTCAD-PGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTC 3172
G WS P+C + +C D G G Q+G+ V F C +G+ L+GS+ C
Sbjct: 1244 GDWSPAAPTC---EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYC 1300
Query: 3173 L---PNLTWSGTPPDCVPHHCRQPET-PTHANVG-ALDLPSMGYTLIYSCQ------EGF 3221
+ W+ + P C C P P + G L++ G + Y+C F
Sbjct: 1301 VLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSF 1360
Query: 3222 SLKGGSEHRTCKAD----GSWTGKPPIC 3245
L G S R C +D G W+ P C
Sbjct: 1361 DLIGESTIR-CTSDPQGNGVWSSPAPRC 1387
Score = 258 bits (660), Expect = 6e-68
Identities = 309/1238 (24%), Positives = 444/1238 (35%), Gaps = 216/1238 (17%)
Query: 2139 YNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCG--------------- 2183
+++ + V F C PG+ + G + CQ W+ LP C C
Sbjct: 1156 FSLNEVVEFRCQPGFVMKGPRRVKCQ--ALNKWEPELPSCSRVCQPPPDVLHAERTQRDK 1213
Query: 2184 GNITSSNGTVYS--PGFPSPYSSSQDCV----WLITVPIGHGVRLNLSLLQTEPSGDFIT 2237
N + YS PG+ ++S C W P + + DF+
Sbjct: 1214 DNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPT----------CEVKSCDDFMG 1263
Query: 2238 IWDGPQQTAP---RLGVFTRSMAKKTVQ---SSSNQVLLKFHRDAATGGIFAIAFSAYPL 2291
+ P +LG + + Q SS++ +L G+ ++ S+ P+
Sbjct: 1264 QLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVL--------AGMESLWNSSVPV 1315
Query: 2292 TK---CPPPTILPNAEVVTEN-EEFNIGDIVRYRCLP------GFTLVGNEILTCKLGTY 2341
+ CP P ++PN + E F G V Y C P F L+G + C
Sbjct: 1316 CEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQ 1375
Query: 2342 LQ--FEGPPPICEV--HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISL 2397
+ P P C + HC PD+
Sbjct: 1376 GNGVWSSPAPRCGILGHCQA---------------------------------PDH---- 1398
Query: 2398 TVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRK 2457
FL K + D P G S + Y P +T N V WSS ++
Sbjct: 1399 ----FLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLV---WSSPKDVCKR 1451
Query: 2458 GFKIRYSAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYH 2517
C P P++G + T Q G I++ C G+RL+GHS A C H
Sbjct: 1452 --------KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAH 1503
Query: 2518 LWSEAIPLCQALSCGLPEAPKNGMVFG---KEYTVGTKAMYSCSEGYH----LQAGAEAT 2570
WS P+CQ + CGLP NG + + G+ Y C+ G + E +
Sbjct: 1504 -WSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPS 1562
Query: 2571 AECL----DTGLWSNRNVPPQC-VPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICD 2625
C G+WS PQC +P C + +VE+G + + + C
Sbjct: 1563 IYCTSNDDQVGIWS--GPAPQCIIPNKC---TPPNVENGILVSDNRSLFSLNEVVEFRCQ 1617
Query: 2626 PGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVY-----GATA 2680
PG+ G R ++CQA KW P+C + P P H T S G
Sbjct: 1618 PGFVMKGPRRVKCQALNKWE--PELPSCSRVC---QPPPEILHGEHTPSHQDNFSPGQEV 1672
Query: 2681 IFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGE-----NYSYR 2735
+SC GY L G+ C G WS RC C + + +G N
Sbjct: 1673 FYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSC---DDFLGQLPHGRVLFPLNLQLG 1729
Query: 2736 GSVVYQCNAGFRLIGMSVRIC---QQDHHWSGKTPFCVLVSCGHPG---SPPHSQMSGDS 2789
V + C+ GFRL G SV C W+ P C + C +P + H+
Sbjct: 1730 AKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGD 1789
Query: 2790 YTVGAVVRYSCIGKR------TLVGNSTRMCGLDGH----WTGSLPHCS-GTSVGVCGDP 2838
G + Y+C L+G ST C D H W+ P C G C P
Sbjct: 1790 IPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTP 1849
Query: 2839 ---GIPAHGIRLGD-SFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCG 2894
+ I + D F GT + + C G+ + S +C N WS + C SCG
Sbjct: 1850 EQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFS-ISCLENLVWSSVEDNCRRKSCG 1908
Query: 2895 NPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNG---TWTGSDPECLVIN 2951
P P N V + F S++ Y C EG+ G S C V+G TW P C +I+
Sbjct: 1909 PPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIIS 1968
Query: 2952 CGDPGIPANGLRLGND---FRYNKTVTYQCVPG------YMMESHRVSVLSCTKD---RT 2999
C P +NG N+ F VTYQC G + + R S+ +KD
Sbjct: 1969 CEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGER-SIYCTSKDDQVGV 2027
Query: 3000 WNGTKPVC-KALMCKPPPLIPNGKVVG--SDFMWGSSVTYACLEGYQLSLPAVFTCEGNG 3056
W+ P C C P + +V G S F + + C G+ + C+ NG
Sbjct: 2028 WSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNG 2087
Query: 3057 SWTGELPQCFPVFCGDPGVPSRGRR---EDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSD 3113
W +LP C V C P G FS V +SC P L G+ C
Sbjct: 2088 RWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQ 2146
Query: 3114 GTWSGTQPSCIDPTLTTCAD-PGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTC 3172
G WS P C T+ +C D G G Q+G+ V F C +G+ L+G + C
Sbjct: 2147 GDWSPEAPRC---TVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHC 2203
Query: 3173 L---PNLTWSGTPPDCVPHHCRQPE---TPTHANVGALDLPSMGYTLIYSCQE------G 3220
+ W+ + P C C P H D+P G + Y+C
Sbjct: 2204 VLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIP-YGKEISYACDTHPDRGMT 2262
Query: 3221 FSLKGGSEHRTCKAD----GSWTGKPPICLEVRPSGRP 3254
F+L G S R C +D G W+ P C P+ P
Sbjct: 2263 FNLIGESSIR-CTSDPQGNGVWSSPAPRCELSVPAACP 2299
Score = 250 bits (638), Expect = 2e-65
Identities = 258/980 (26%), Positives = 366/980 (37%), Gaps = 135/980 (13%)
Query: 2346 GPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSE 2405
GPP C LL V++ + P ++ Q WL P +LT E+
Sbjct: 13 GPPAPGLPFCCGGSLLA----VVVLLALPVAWGQCNAPEWLPFARPT---NLTDEFEFPI 65
Query: 2406 KQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465
Y +E G SG+ P + NSV+ G K R
Sbjct: 66 GTYLNYECRPGYSGR-------------PFSIICLKNSVWT-----------GAKDRCRR 101
Query: 2466 PYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPL 2525
C P P++G + Q G I + C GYRL+G S A C +W P+
Sbjct: 102 KSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTV-IWDNETPI 160
Query: 2526 CQALSCGLPEAPKNGMVFG---KEYTVGTKAMYSCSEG------YHL--QAGAEATAECL 2574
C + CGLP NG + + G+ Y C+ G + L + T+
Sbjct: 161 CDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDD 220
Query: 2575 DTGLWSNRNVPPQC-VPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQ 2633
G+WS PQC +P C + +VE+G + + + C PG+ G
Sbjct: 221 QVGIWS--GPAPQCIIPNKC---TPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 275
Query: 2634 RVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLS-----VYGATAIFSCNSGY 2688
R ++CQA KW P+C + P P H T G +SC GY
Sbjct: 276 RRVKCQALNKWE--PELPSCSRVC---QPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY 330
Query: 2689 TLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGE-----NYSYRGSVVYQCN 2743
L G+ C G WS + C C + + +NG N V + C+
Sbjct: 331 DLRGAASMRCTPQGDWSPAAPTCEVKSC---DDFMGQLLNGRVLFPVNLQLGAKVDFVCD 387
Query: 2744 AGFRLIGMSVRIC---QQDHHWSGKTPFCVLVSCGHPGSPPHSQMSG---DSYTVGAVVR 2797
GF+L G S C + W+ P C + C P P+ + +G + + G V
Sbjct: 388 EGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVN 447
Query: 2798 YSCI------GKRTLVGNSTRMCGLD----GHWTGSLPHCSGTSVGVCGDPGIPAHGI-- 2845
Y+C L+G ST C D G W+ P C G+ G P H +
Sbjct: 448 YTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC-----GILGHCQAPDHFLFA 502
Query: 2846 -----RLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPS 2900
F GT +++ C + R S TC N WS + C SC P P
Sbjct: 503 KLKTQTNASDFPIGTSLKYECRPEYYGRPFS-ITCLDNLVWSSPKDVCKRKSCKTPPDPV 561
Query: 2901 NARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGT---WTGSDPECLVINCGDPGI 2957
N V + S I Y C G+ G S C ++G W+ P C I CG P
Sbjct: 562 NGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPT 621
Query: 2958 PANGLRLG---NDFRYNKTVTYQCVPG----YMMESHRVSVLSCTKD----RTWNGTKPV 3006
ANG + +F Y VTY+C PG + E + CT + W+G P
Sbjct: 622 IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 681
Query: 3007 CKALMCKPPPLIPNGKVVGSD---FMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELP 3063
C PP + NG +V + F V + C G+ + P C+ W ELP
Sbjct: 682 CIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP 741
Query: 3064 QCFPVFCGDPGV--PSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQP 3121
C V P V R +R+ FS V +SC P L G+ C G WS P
Sbjct: 742 SCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAP 801
Query: 3122 SCIDPTLTTCAD-PGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCL---PNLT 3177
+C + +C D G G Q+G+ V F C +G+ L+GS+ C+
Sbjct: 802 TC---EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 858
Query: 3178 WSGTPPDCVPHHCRQPET-PTHANVG-ALDLPSMGYTLIYSCQ------EGFSLKGGSEH 3229
W+ + P C C P P + G L++ G T+ Y+C F L G S
Sbjct: 859 WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTI 918
Query: 3230 RTCKAD----GSWTGKPPIC 3245
R C +D G W+ P C
Sbjct: 919 R-CTSDPQGNGVWSSPAPRC 937
Score = 130 bits (327), Expect = 2e-29
Identities = 520/2420 (21%), Positives = 798/2420 (32%), Gaps = 524/2420 (21%)
Query: 344 PDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRAR 403
PD ER +R +F G V ++C GYDL+G+ + C D WS P C +
Sbjct: 301 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGD----WSPAAPTCEVK 356
Query: 404 MCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVG 463
CD +F Q N L P + A +F + G+
Sbjct: 357 SCD-------------DFMGQLLNG-------RVLFPVNLQLGAKVDFVCDEGFQ----- 391
Query: 464 DGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGD 523
L G+S +++ +W +S EQ C
Sbjct: 392 --------------LKGSSASYCVLAGMESLW--------------NSSVPVCEQIFCPS 423
Query: 524 PGIPAYGRREGSR---FHHGDTLKFECQP------AFELVGQKAITC----QKNNQWSAK 570
P + GR G F G T+ + C P +F+L+G+ I C Q N WS+
Sbjct: 424 PPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSP 483
Query: 571 KPGC--VFSC----FFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDID 624
P C + C F F + ++P C RP S I N +
Sbjct: 484 APRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFS-ITCLDNLVW 542
Query: 625 VEPQFDFLVIKDGATAEAPVLG---TFSGNQLPSSIT---SSGH--VARLEFQTDHSTGK 676
P+ D K T PV G + Q+ S I ++GH + + S
Sbjct: 543 SSPK-DVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNA 601
Query: 677 RGFNITFTTFRHNECPDPGVPVNGKRFG---DSLQLGSSISFLCDEGFLGTQ-----GSE 728
++ + C P NG ++ GS +++ C+ G G + G
Sbjct: 602 AHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEP 661
Query: 729 TITCVLKEGSV-VWNSAVLRCEAPCGGHLTSP---SGTILSPGWPGFYKDALSCAWVIE- 783
+I C + V +W+ +C P T P +G ++S + S V+E
Sbjct: 662 SIYCTSNDDQVGIWSGPAPQCIIP--NKCTPPNVENGILVSDN-----RSLFSLNEVVEF 714
Query: 784 -AQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLF 842
QPG+ +K +N E+ P V H + + + S + +
Sbjct: 715 RCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFY 774
Query: 843 STDKSHSDIGFQLRYET---ITLQSDHCLDPGIPVNGQRHGNDF---------------Y 884
S + G+ LR T Q D P P + +DF
Sbjct: 775 SCEP-----GYDLRGAASMRCTPQGD--WSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQ 827
Query: 885 VGALVTFSCDSGYTLSDGEPLEC---EPNFQWSRALPSCEALCGGFIQGSSGTILSPGFP 941
+GA V F CD G+ L C W+ ++P CE I P P
Sbjct: 828 LGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE------------QIFCPS-P 874
Query: 942 DFYPNNLNCTWIIET-SHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGS-RLP 999
PN + +E GK V +T H + G + LI E+ Q G P
Sbjct: 875 PVIPNGRHTGKPLEVFPFGKTVNYTCDP-HPDRGTSFDLIGESTIRCTSDPQGNGVWSSP 933
Query: 1000 APISAGLYGNFTAQVRFI----------SDF----SMSYE--------GFNIT------- 1030
AP G+ G+ A F+ SDF S+ YE F+IT
Sbjct: 934 AP-RCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVW 992
Query: 1031 FSEYDL---EPCEEPEVPAYS-IRKGLQFGVGDTLTFSCFPGYRLEGTARITC-LGGRRR 1085
S D+ + C+ P P + VG + +SC G+RL G + C L G
Sbjct: 993 SSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAA 1052
Query: 1086 LWSSPLPRCV-AECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFE 1144
WS+ P C CG T G +S N N ++ + + + PG G + FE
Sbjct: 1053 HWSTKPPICQRIPCGLPPTIANGDFISTN---RENFHYGSVVTYRCNPGSG---GRKVFE 1106
Query: 1145 L---------SEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWL--------- 1186
L S D + ++ G + + + L S + SL+
Sbjct: 1107 LVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRC 1166
Query: 1187 --DFITDAENTSKGFELHFSSFELIKCE-----DPGTPKFGYKVHDEGHFA-GSSVSFSC 1238
F+ K L+ EL C P D+ +F+ G V +SC
Sbjct: 1167 QPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSC 1226
Query: 1239 DPGYSLRGSEELLCLSGERRTWDRPLPTC-VAECGGTVRGEVSGQVLSPGYPAPYEHNLN 1297
+PGY LRG+ + C + W PTC V C + ++G+VL P
Sbjct: 1227 EPGYDLRGAASMRCT--PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP----------- 1273
Query: 1298 CIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGP-ALPKDLHSTFN 1356
+ + G + D + G LK S + + S +N
Sbjct: 1274 ----VNLQLGAKV-------------------DFVCDEGFQLKGSSASYCVLAGMESLWN 1310
Query: 1357 SVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQNGSRSGDSWEA---GDSTVFQCDP 1413
S V V C P + NG +G E G + + CDP
Sbjct: 1311 SSV------------------PVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDP 1352
Query: 1414 ------GYALQGSAEISCVK-IENRFFWQPSPPTC--IAPCGGDLTGPSGVILSPNYPEP 1464
+ L G + I C + W P C + C + +
Sbjct: 1353 HPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD 1412
Query: 1465 YPPGKECDWKVTVSPDYV-----IALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFY--- 1516
+P G K P+Y I + N+ P D + P+ G +
Sbjct: 1413 FPIGTSL--KYECRPEYYGRPFSITCLDNLVWSSP-KDVCKRKSCKTPPDPVNGMVHVIT 1469
Query: 1517 GSQLPGRIE-SSSNSLFLAFRSDASVSNAGFVIDYTENP----RESCFDPGSIKNGTRVG 1571
Q+ RI S + L S A +G ++ P R C P +I NG +
Sbjct: 1470 DIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFIS 1529
Query: 1572 S---DLKLGSSVTYYCHGG------YEVEGTSTLSCILGPDGKPVWNNPRPVCTAP--CG 1620
+ + GS VTY C+ G +E+ G ++ C D +W+ P P C P C
Sbjct: 1530 TNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 1589
Query: 1621 GQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALND-VVEVHDGHS 1679
V +G+++S N ++ S + F P +V+ G ALN E+
Sbjct: 1590 PPNV-ENGILVSDN--RSLFSLNEVVEFRCQP-GFVMKGPRRVKCQALNKWEPELPSCSR 1645
Query: 1680 QHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKG--LAPARGFHFVYQA-----VPRTSA 1732
L G HT + Q + G L A H Q PR +
Sbjct: 1646 VCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAV 1705
Query: 1733 TQCSS-VPEPRYGKRL-GSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAP 1790
C + + +G+ L + +GA V F C+ G+ L+GS C+ V G + WN S P
Sbjct: 1706 KSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLV-GMRSLWNNSVP 1764
Query: 1791 TCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSL 1850
C I P P LN + P G + +S+ + + D
Sbjct: 1765 VC------------EHIFCPN-PPAILNGRH----TGTPSGDIPYGKEISYTCDPHPD-- 1805
Query: 1851 EVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCP 1910
T ++G +T+ + N ++ +S H KT
Sbjct: 1806 -----RGMTFNLIGE---STIRCTSDPHGNGVWSSPAPRCELSVRAGHC--KTPEQFPFA 1855
Query: 1911 EPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQ-CG 1969
P +P N + + V ++++C PGY + + ISC+ V W+ C + CG
Sbjct: 1856 SPTIPINDFE----FPVGTSLNYECRPGYFGKMFS-ISCLENLV--WSSVEDNCRRKSCG 1908
Query: 1970 GTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPY 2029
E G++ I FG+ + N+S ++ + P
Sbjct: 1909 PPPEPFNGMV-----------------HINTDTQFGSTV---NYSC---NEGFRLIGSPS 1945
Query: 2030 ETSRMMGR---FSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSFL 2086
T + G + ++S T+ +S NR F + ++Q +
Sbjct: 1946 TTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSF---HNGTVVTYQCHTGP 2002
Query: 2087 RGFDLSELERTNS---TPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAG----Y 2139
G L EL S T VW P +C PE +R G +
Sbjct: 2003 DGEQLFELVGERSIYCTSKDDQVGVWS-SPPPRCISTNKCTAPE--VENAIRVPGNRSFF 2059
Query: 2140 NVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPC-------GGNITSSNGT 2192
+ + + F C PG+ + G + CQ TN W LP C C G T S+
Sbjct: 2060 TLTEIIRFRCQPGFVMVGSHTVQCQ--TNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQD 2117
Query: 2193 VYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVF 2252
+SPG YS + +R + L P GD+ APR V
Sbjct: 2118 NFSPGQEVFYSCEP----------SYDLR-GAASLHCTPQGDW-------SPEAPRCTV- 2158
Query: 2253 TRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEF 2312
+S Q +VLL PL
Sbjct: 2159 -KSCDDFLGQLPHGRVLL-------------------PL-------------------NL 2179
Query: 2313 NIGDIVRYRCLPGFTLVGNEILTCKL-GTYLQFEGPPPICE-VHCPTNELLTDS--TGVI 2368
+G V + C GF L G C L G + P+CE + CP + + TG
Sbjct: 2180 QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTP 2239
Query: 2369 LSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALS 2428
G P + S+ PD ++ L
Sbjct: 2240 F-----GDIPYGKEISYACDTHPDRGMTFN----------------------------LI 2266
Query: 2429 GNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAPLHGFILGQTSTQPG 2488
G S N V WSS R + + P+ P+ +I G S
Sbjct: 2267 GESSIRCTSDPQGNGV---WSSPAP--RCELSVPAACPH--PPKIQNGHYIGGHVSLYLP 2319
Query: 2489 G-SIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLP---EAPKNGMVFG 2544
G +I + C+ GY LVG CT QG +WS+ C+ ++C P +
Sbjct: 2320 GMTISYICDPGYLLVGKGFIFCT--DQG--IWSQLDHYCKEVNCSFPLFMNGISKELEMK 2375
Query: 2545 KEYTVGTKAMYSCSEGYHLQ 2564
K Y G C +GY L+
Sbjct: 2376 KVYHYGDYVTLKCEDGYTLE 2395
Score = 124 bits (311), Expect = 2e-27
Identities = 297/1426 (20%), Positives = 495/1426 (34%), Gaps = 286/1426 (20%)
Query: 687 RHNECPDPGVPVNGK-RFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAV 745
R C +P PVNG +Q GS I + C +G+ GS + TC++ +V+W++
Sbjct: 100 RRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYR-LIGSSSATCIISGDTVIWDNET 158
Query: 746 LRCE-APCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYD 804
C+ PCG T +G +S F+ ++ PG + F+ Y
Sbjct: 159 PICDRIPCGLPPTITNGDFISTNRENFHYGSVV---TYRCNPGSGGRKVFELVGEPSIYC 215
Query: 805 TLEVRDGRTYS--APLIGVYHGTQVPQ----FLISTSNYLYLLFSTDKSHSDIGFQLR-Y 857
T +S AP + + P L+S + L+ L + GF ++
Sbjct: 216 TSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 275
Query: 858 ETITLQSDHCLDPGIP---------------VNGQRHGNDFYVGALVTFSCDSGYTLSDG 902
+ Q+ + +P +P QR ++F G V +SC+ GY L
Sbjct: 276 RRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
Query: 903 EPLECEPNFQWSRALPSCEA-LCGGFI-QGSSGTILSPGFPDFYPNNLNCTWIIETSHGK 960
+ C P WS A P+CE C F+ Q +G +L P
Sbjct: 336 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP---------------------- 373
Query: 961 GVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDF 1020
+L+ G + + G QL GS + AG+ + + V
Sbjct: 374 --------VNLQLGAKVDFVCDEGF------QLKGSSASYCVLAGMESLWNSSVPVCEQI 419
Query: 1021 SMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQ---FGVGDTLTFSCFP------GYRL 1071
C P V G F G T+ ++C P + L
Sbjct: 420 F-----------------CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDL 462
Query: 1072 EGTARITCLGGRR--RLWSSPLPRC--VAEC--------GNSVTGTQGTLLSPNFPVNYN 1119
G + I C + +WSSP PRC + C T T + +FP+ +
Sbjct: 463 IGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNAS----DFPIGTS 518
Query: 1120 NNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGVFS--HSEMMGVTL 1177
+EC +P L + S DV K + G+ +G +
Sbjct: 519 LKYECRPEYYGRPFSITCLDNLVWS-SPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRI 577
Query: 1178 N-STSSSLWLDFITDAENTSKGFELHFSS----FELIKCEDPGTPKFG--YKVHDEGHFA 1230
N S ++ L + AE G H+S+ + I C P T G + E
Sbjct: 578 NYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHY 637
Query: 1231 GSSVSFSCDPG------YSLRGSEELLCLSGERRT--WDRPLPTCVAECGGTVRGEVSGQ 1282
GS V++ C+PG + L G + C S + + W P P C+ T +G
Sbjct: 638 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGI 697
Query: 1283 VLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVH-DVLRIWDGPVESGVLLKE 1341
++S +LN + + G F++ V L W+ + S + +
Sbjct: 698 LVSDNRSL---FSLNEVVEFRCQPG------FVMKGPRRVKCQALNKWEPELPSCSRVCQ 748
Query: 1342 LSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVS---TATSCNDPGIPQNGSRSG 1398
L + F++ + G+ ++ + S T P P +S
Sbjct: 749 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSC 808
Query: 1399 DSW---------------EAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIA 1443
D + + G F CD G+ L+GS+ CV W S P C
Sbjct: 809 DDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQ 868
Query: 1444 P-CGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIY 1502
C P+G E +P GK ++ PD +D +
Sbjct: 869 IFCPSPPVIPNGRHTGKPL-EVFPFGKTVNYTCDPHPD-----------RGTSFDLIGES 916
Query: 1503 DGRDSLSPLIGSFYGSQLP-----GRIESSSNSLFLAFRSDASVSN--AGFVIDYTENP- 1554
R + P + S P G ++ + LF ++ + S+ G + Y P
Sbjct: 917 TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPE 976
Query: 1555 ------------------------RESCFDPGSIKNG-TRVGSDLKLGSSVTYYCHGGYE 1589
R+SC P NG V +D+++GS + Y C G+
Sbjct: 977 YYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHR 1036
Query: 1590 VEGTSTLSCILGPDGKPVWNNPRPVC-TAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYF 1648
+ G S+ CIL + W+ P+C PCG ++G +S N +N+ G + Y
Sbjct: 1037 LIGHSSAECILSGNAAH-WSTKPPICQRIPCGLPPTIANGDFISTN-RENFHYGSVVTYR 1094
Query: 1649 VTV----PKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSL------SGSHTGESLP 1698
K + + G+ + + T+ +D V + G + + + +G ++
Sbjct: 1095 CNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRS 1154
Query: 1699 LATSNQVLIKFSAKGLAPARGFHFVYQAVPR------TSATQCSSVPEPRYGKRLGSD-- 1750
L + N+V+ G QA+ + + + C P+ + +R D
Sbjct: 1155 LFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKD 1214
Query: 1751 -FSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERRGTILS 1809
FS G V + C GY L+G+ + C P W+ +APTC V + + G +L+
Sbjct: 1215 NFSPGQEVFYSCEPGYDLRGAASMRCTP----QGDWSPAAPTCEVK---SCDDFMGQLLN 1267
Query: 1810 PGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSFSGT 1869
+++ P + + V FV ++ + + GS +
Sbjct: 1268 --------------GRVLFPVNLQLGAK-VDFVCDEGFQ-------------LKGSSASY 1299
Query: 1870 TVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTG---ERYL 1926
V A + S N S + V F CP P V NG TG E +
Sbjct: 1300 CVLAGMESLWN-------SSVPVCEQIF-----------CPSPPVIPNGRHTGKPLEVFP 1341
Query: 1927 VNDVVSFQCEP------GYALQGHAHISCM--PGTVRRWNYPPPLC 1964
V++ C+P + L G + I C P W+ P P C
Sbjct: 1342 FGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 1387
Score = 108 bits (269), Expect = 1e-22
Identities = 307/1431 (21%), Positives = 476/1431 (33%), Gaps = 336/1431 (23%)
Query: 143 GRLPNG-IQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCH-AGSENSATWDFPLPSCRADD 200
G+L NG + LG KV + C+ GF L+G + C AG E+ W+ +P C
Sbjct: 813 GQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMES--LWNSSVPVCE--- 867
Query: 201 ACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVF-------IDFQLEDGY 253
Q S P P+ H + G T+ F L
Sbjct: 868 --------QIFCPSPPVIPNGRHTGKPLE---VFPFGKTVNYTCDPHPDRGTSFDLIGES 916
Query: 254 DFLEVTGTEGSSLWFTGASLPAPVISSKN---------WLRLHFTSDGNHRQRGFSAQYQ 304
+ +G+ +W S PAP + +L ++ + G S +Y+
Sbjct: 917 TIRCTSDPQGNGVW----SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYE 972
Query: 305 VKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGK-RLGSDFRLGS 363
+ + + + + + S V + C P P G + +D ++GS
Sbjct: 973 CRPEYYGRPFSITCLDNLVWSSPKDVCKR-------KSCKTPPDPVNGMVHVITDIQVGS 1025
Query: 364 SVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPI 423
+ ++C G+ L G C+ +S A WS P+C+ C G I + +F
Sbjct: 1026 RINYSCTTGHRLIGHSSAECI-LSGNAAHWSTKPPICQRIPC-----GLPPTIANGDFIS 1079
Query: 424 QYDNNAHCVWIIT-ALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTS 482
N H ++T NP G GG+ ++ L G
Sbjct: 1080 TNRENFHYGSVVTYRCNP----------------------GSGGRK------VFELVGE- 1110
Query: 483 VPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDT 542
P + ++N ++ + K + +E GI R S F +
Sbjct: 1111 -PSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVEN------GILVSDNR--SLFSLNEV 1161
Query: 543 LKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHL 602
++F CQP F + G + + CQ N+W + P C C P V+ + D N
Sbjct: 1162 VEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC----QPPPDVLHAERTQRDKDNF- 1216
Query: 603 HCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGH 662
P + + EP +D A + T G+ P++
Sbjct: 1217 --------SPGQEVFYS-----CEPGYDL-------RGAASMRCTPQGDWSPAA------ 1250
Query: 663 VARLEFQTDHSTGKRGFNITFTTFRHNECPD-PGVPVNGK-RFGDSLQLGSSISFLCDEG 720
T C D G +NG+ F +LQLG+ + F+CDEG
Sbjct: 1251 ---------------------PTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEG 1289
Query: 721 FLGTQGSETITCVLKEGSVVWNSAVLRCEAP-CGGHLTSPSGTILSPGWPGFYKDALSCA 779
F +GS CVL +WNS+V CE C P+G F A
Sbjct: 1290 F-QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVF---PFGKA 1345
Query: 780 WVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYS--APLIGVYHGTQVPQFLISTSNY 837
P +FD T + + +S AP G+ Q P + +
Sbjct: 1346 VNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFL----F 1401
Query: 838 LYLLFSTDKSHSDIGFQLRYE----------TIT-------------LQSDHCLDPGIPV 874
L T+ S IG L+YE +IT + C P PV
Sbjct: 1402 AKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPV 1461
Query: 875 NGQRHG-NDFYVGALVTFSCDSGYTLSDGEPLEC---EPNFQWSRALPSCEAL-CGGFIQ 929
NG H D VG+ + +SC +G+ L EC WS P C+ + CG
Sbjct: 1462 NGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPT 1521
Query: 930 GSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITEN----GS 985
++G +S +F+ ++ S G+ VF G + T N G
Sbjct: 1522 IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELV-------GEPSIYCTSNDDQVGI 1574
Query: 986 FTQPLRQ--LTGSRLPAPISAGLYGN-------------FTAQVRFISDFSMSYEGFNIT 1030
++ P Q + P + G+ + F Q F+ + +
Sbjct: 1575 WSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALN 1634
Query: 1031 FSEYDLEPCEEPEVPAYSIRKGL-------QFGVGDTLTFSCFPGYRLEGTARITCLGGR 1083
E +L C P I G F G + +SC PGY L G A + C
Sbjct: 1635 KWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCT--P 1692
Query: 1084 RRLWSSPLPRCVAECGNSVTG--TQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKAR 1141
+ WS PRC + + G G +L FP+N +QL A+
Sbjct: 1693 QGDWSPEAPRCAVKSCDDFLGQLPHGRVL---FPLN------------------LQLGAK 1731
Query: 1142 -AFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFE 1200
+F EG LK G++ SH ++G+ SLW + + E+
Sbjct: 1732 VSFVCDEGFRLK---GSS--------VSHCVLVGM------RSLWNNSVPVCEH------ 1768
Query: 1201 LHFSSFELIKCEDP---------GTPKFGYKVHDEGHFAGSSVSFSCDP------GYSLR 1245
I C +P GTP G +S++CDP ++L
Sbjct: 1769 --------IFCPNPPAILNGRHTGTPSGDIPY-------GKEISYTCDPHPDRGMTFNLI 1813
Query: 1246 GSEELLCLSGE--RRTWDRPLPTC-VAECGGTVRGEVSGQVLSPGYPA-PYEHNLNCIWT 1301
G + C S W P P C ++ G + SP P +E +
Sbjct: 1814 GESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLN 1873
Query: 1302 IEAEAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQ 1361
E G G F + E + +W VE K P P + N+
Sbjct: 1874 YECRPG-YFGKMFSISCLENL-----VWSS-VEDNCRRKSCGPPPEPFNGMVHINTDTQF 1926
Query: 1362 FSTDFFTSKQGFAIQFSVSTA-------------------TSCNDPGIPQNG---SRSGD 1399
ST ++ +GF + S ST SC P NG S +
Sbjct: 1927 GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRT 1986
Query: 1400 SWEAGDSTVFQCDPG------YALQGSAEISCVKIENRF-FWQPSPPTCIA 1443
S+ G +QC G + L G I C +++ W PP CI+
Sbjct: 1987 SFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCIS 2037
Score = 95.1 bits (235), Expect = 1e-18
Identities = 225/1017 (22%), Positives = 342/1017 (33%), Gaps = 243/1017 (23%)
Query: 327 KTSVLTQVGVSQGHNMCPDPGIPERGK-RLGSDFRLGSSVQFTCNEGYDLQGSKRITCMK 385
K SV T C +P P G + + GS ++++C +GY L GS TC+
Sbjct: 88 KNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCI- 146
Query: 386 VSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIIT-ALNPSKVI 444
+S W + P+C C G IT+ +F N H ++T NP
Sbjct: 147 ISGDTVIWDNETPICDRIPC-----GLPPTITNGDFISTNRENFHYGSVVTYRCNP---- 197
Query: 445 KLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSG 504
G GG+ ++ L G P + ++N ++
Sbjct: 198 ------------------GSGGRK------VFELVGE--PSIYCTSNDDQVGIWSGPAPQ 231
Query: 505 SSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKN 564
+ K + +E GI R S F + ++F CQP F + G + + CQ
Sbjct: 232 CIIPNKCTPPNVEN------GILVSDNR--SLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 283
Query: 565 NQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDID 624
N+W + P C C P V+ + D N P + +
Sbjct: 284 NKWEPELPSCSRVC----QPPPDVLHAERTQRDKDNF---------SPGQEVFYS----- 325
Query: 625 VEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFT 684
EP +D A + T G+ P++
Sbjct: 326 CEPGYDL-------RGAASMRCTPQGDWSPAA---------------------------P 351
Query: 685 TFRHNECPD-PGVPVNGK-RFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWN 742
T C D G +NG+ F +LQLG+ + F+CDEGF +GS CVL +WN
Sbjct: 352 TCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGF-QLKGSSASYCVLAGMESLWN 410
Query: 743 SAVLRCEAPCGGHLTSPSGTILSPG-WPGFYKDALSCAWVIE--AQPGYPIKITFDRFKT 799
S+V CE + PS ++ G G + + P +FD
Sbjct: 411 SSVPVCE-----QIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGE 465
Query: 800 EVNYDTLEVRDGRTYS--APLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRY 857
T + + +S AP G+ Q P + + L T+ S IG L+Y
Sbjct: 466 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFL----FAKLKTQTNASDFPIGTSLKY 521
Query: 858 E----------TIT-------------LQSDHCLDPGIPVNGQRHG-NDFYVGALVTFSC 893
E +IT + C P PVNG H D VG+ + +SC
Sbjct: 522 ECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSC 581
Query: 894 DSGYTLSDGEPLECEPN---FQWSRALPSCEAL-CGGFIQGSSGTILSPGFPDFYPNNLN 949
+G+ L EC + WS P C+ + CG ++G +S +F+ ++
Sbjct: 582 TTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVV 641
Query: 950 CTWIIETSHGKGVFFTFHTFHLESGHDYLLITEN----GSFTQPLRQ--LTGSRLPAPIS 1003
S G+ VF G + T N G ++ P Q + P +
Sbjct: 642 TYRCNPGSGGRKVFELV-------GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVE 694
Query: 1004 AGLYGN-------------FTAQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSI- 1049
G+ + F Q F+ + + E +L C P +
Sbjct: 695 NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVL 754
Query: 1050 ------RKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVT 1103
R F G + +SC PGY L G A + C + WS P C + S
Sbjct: 755 HAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT--PQGDWSPAAPTCEVK---SCD 809
Query: 1104 GTQGTLLSPN--FPVNYNNNHECIYSIQTQPGKGIQLKARA-FELSEGDVLKVYDGNNNS 1160
G LL+ FPVN +QL A+ F EG LK +S
Sbjct: 810 DFMGQLLNGRVLFPVN------------------LQLGAKVDFVCDEGFQLK-----GSS 846
Query: 1161 ARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCEDPGTPKFG 1220
A S+ + G+ SLW + E I C P G
Sbjct: 847 A------SYCVLAGM------ESLWNSSVPVCEQ--------------IFCPSPPVIPNG 880
Query: 1221 YKVHD--EGHFAGSSVSFSCDP------GYSLRGSEELLCLSGER--RTWDRPLPTC 1267
E G +V+++CDP + L G + C S + W P P C
Sbjct: 881 RHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 937
Score = 84.3 bits (207), Expect = 2e-15
Identities = 231/1082 (21%), Positives = 363/1082 (33%), Gaps = 244/1082 (22%)
Query: 343 CPDPGIPERGK-RLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCR 401
C P P G + +D ++GS + ++C G+ L G C+ +S A WS P+C+
Sbjct: 1454 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECI-LSGNTAHWSTKPPICQ 1512
Query: 402 ARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLT 461
C G I + +F N H ++T
Sbjct: 1513 RIPC-----GLPPTIANGDFISTNRENFHYGSVVTY---------------------RCN 1546
Query: 462 VGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSC 521
+G G+ ++ L G P + ++N ++ + K + +E G
Sbjct: 1547 LGSRGRK------VFELVGE--PSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENG-- 1596
Query: 522 GDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFN 581
I R S F + ++F CQP F + G + + CQ N+W + P C C
Sbjct: 1597 ----ILVSDNR--SLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC--- 1647
Query: 582 FTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHL-AFNDIDVEPQFDFLVIKDGATA 640
P +L + + ++ + E L + PQ D+ +
Sbjct: 1648 --QPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDW-------SP 1698
Query: 641 EAPVLGTFSGNQLPSSITSSGHV---------ARLEFQTDHSTGKRGFNITFTTF----- 686
EAP S + + G V A++ F D +G +++
Sbjct: 1699 EAPRCAVKSCDDFLGQLPH-GRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRS 1757
Query: 687 ---------RHNECPDPGVPVNGKRFGD---SLQLGSSISFLCDEG-----FLGTQGSET 729
H CP+P +NG+ G + G IS+ CD G T
Sbjct: 1758 LWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGEST 1817
Query: 730 ITCVLK-EGSVVWNSAVLRCEAPC-GGHLTSPSG-TILSPGWP-GFYKDALSCAWVIEAQ 785
I C G+ VW+S RCE GH +P SP P ++ + + E +
Sbjct: 1818 IRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECR 1877
Query: 786 PGYPIKITFDRFKTEVNYDTLEVRDGRTYSAP----LIGVYHGTQVPQFLISTSNY---- 837
PGY K+ + + ++E R P G+ H QF ST NY
Sbjct: 1878 PGYFGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFG-STVNYSCNE 1936
Query: 838 -LYLLFSTDKSHSDIGFQLRYETIT--LQSDHCLDPGIPVNGQRHGND---FYVGALVTF 891
L+ S + G + ++ + C P NG + N+ F+ G +VT+
Sbjct: 1937 GFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTY 1996
Query: 892 SCDSGYTLSDGEPL-------------ECEPNFQWSRALPSCEALCGGFIQGSSGTILSP 938
C +G DGE L + + WS P C + I P
Sbjct: 1997 QCHTG---PDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVP 2053
Query: 939 GFPDFYPNNLNCTWIIETSHGKG-VFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSR 997
G F+ T II G V HT ++ NG + L SR
Sbjct: 2054 GNRSFF----TLTEIIRFRCQPGFVMVGSHTVQCQT---------NGRWGPKLPHC--SR 2098
Query: 998 LPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCEE----------PEVPAY 1047
+ P L+G T + +FS E F YDL PE P
Sbjct: 2099 VCQPPPEILHGEHTLSHQ--DNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC 2156
Query: 1048 SIRK---------------GLQFGVGDTLTFSCFPGYRLEGTARITC-LGGRRRLWSSPL 1091
+++ L +G ++F C G+RL+G + C L G + LW+S +
Sbjct: 2157 TVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSV 2216
Query: 1092 PRCVAECGNSVTGTQGTLLSPNFPVNYNNNH------------ECIYSIQTQPGKGIQLK 1139
P C + PN P N H E Y+ T P +G+
Sbjct: 2217 PVCEQ------------IFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFN 2264
Query: 1140 ARAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSS----------------- 1182
+ E + D N GV+S S L+ ++
Sbjct: 2265 L----IGESSIRCTSDPQGN-----GVWS-SPAPRCELSVPAACPHPPKIQNGHYIGGHV 2314
Query: 1183 SLWLDFITDAENTSKGFELHFSSFELIKCEDPGT---------------PKFGYKVHDE- 1226
SL+L +T + G+ L F I C D G P F + E
Sbjct: 2315 SLYLPGMTISYICDPGYLLVGKGF--IFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKEL 2372
Query: 1227 ----GHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAEC-GGTVRGEVSG 1281
+ G V+ C+ GY+L GS C + +R WD PL C + + G +SG
Sbjct: 2373 EMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDR--WDPPLAKCTSRTHDALIVGTLSG 2430
Query: 1282 QV 1283
+
Sbjct: 2431 TI 2432
Score = 48.9 bits (115), Expect = 9e-05
Identities = 104/483 (21%), Positives = 171/483 (35%), Gaps = 85/483 (17%)
Query: 142 PGRLPNGI---QQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRA 198
P + NGI S F+L + V + C GF ++G + C A ++ W+ LPS
Sbjct: 1590 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPS--- 1642
Query: 199 DDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEV 258
C + I+ H PS N + G + + E GYD
Sbjct: 1643 ---CSRVCQPPPEILHGEHTPSHQDNFSP---------GQEVF-----YSCEPGYDLRGA 1685
Query: 259 TGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIE-LKSRGVK 317
+ P + S + F H + F Q+ ++ + G +
Sbjct: 1686 ASLHCTPQGDWSPEAPRCAVKSCD----DFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFR 1741
Query: 318 LMPSKDNSQKTSVL--------TQVGVSQGHNMCPDPGIPERGKRLGS---DFRLGSSVQ 366
L K +S VL V V + H CP+P G+ G+ D G +
Sbjct: 1742 L---KGSSVSHCVLVGMRSLWNNSVPVCE-HIFCPNPPAILNGRHTGTPSGDIPYGKEIS 1797
Query: 367 FTCNE------GYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGI-ITSP 419
+TC+ ++L G I C WS P C + H + P SP
Sbjct: 1798 YTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASP 1857
Query: 420 NFPIQYDNNAHCVWIITALN----PSKVIKL----AFEEFDLERGYDTLTVGDGGQDGDQ 471
PI N + T+LN P K+ E D G +
Sbjct: 1858 TIPI----NDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCGPPPEP 1913
Query: 472 -KTVLYILTGTSVPDLIVSTNHQMWLLFQTDG-----SGSSLGFKASYEEIEQGSCGDPG 525
+++I T T + + ++ + L + SG+++ + E SC P
Sbjct: 1914 FNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPP 1973
Query: 526 IPAYG---RREGSRFHHGDTLKFEC------QPAFELVGQKAITC-QKNNQ---WSAKKP 572
+ G + FH+G + ++C + FELVG+++I C K++Q WS+ P
Sbjct: 1974 TISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPP 2033
Query: 573 GCV 575
C+
Sbjct: 2034 RCI 2036
Score = 48.5 bits (114), Expect = 1e-04
Identities = 53/248 (21%), Positives = 91/248 (36%), Gaps = 50/248 (20%)
Query: 1726 AVPRTSATQCSSVPEPRYGK-RLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQ 1784
A R C + P+P G + G+ +++ C GY L GS C+ + G
Sbjct: 95 AKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCI-ISGDTVI 153
Query: 1785 WNVSAPTCV-VPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVT 1843
W+ P C +PCG T G +S + S VV++
Sbjct: 154 WDNETPICDRIPCGLPPTITNGDFISTNRENFHYGS------------------VVTYRC 195
Query: 1844 EQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 1903
+VF+ ++G S + TSN + +S +
Sbjct: 196 NPGSGGRKVFE-------LVGEPS-------IYCTSNDDQVGIWSGPAPQC--------- 232
Query: 1904 VGLSSCPEPAVPSNGVKTGER---YLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYP 1960
+ + C P V NG+ + + +N+VV F+C+PG+ ++G + C + +W
Sbjct: 233 IIPNKCTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ--ALNKWEPE 289
Query: 1961 PPLCIAQC 1968
P C C
Sbjct: 290 LPSCSRVC 297
Score = 47.0 bits (110), Expect = 3e-04
Identities = 111/530 (20%), Positives = 180/530 (33%), Gaps = 107/530 (20%)
Query: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSA--QGFHATYE----VLPSHTC 139
PP+P N + + V+ + RLI + + G + T++ + +C
Sbjct: 1910 PPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISC 1969
Query: 140 GNPGRLPNG---IQQGSTFNLGDKVRYSCNLG------FFLEGHAVLTCHAGSENSATWD 190
P + NG ++F+ G V Y C+ G F L G + C + + W
Sbjct: 1970 EPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWS 2029
Query: 191 FPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLE 250
P P C + + C ++P + + ++ L E+ I F+ +
Sbjct: 2030 SPPPRCISTNKC-----------TAPEVENAIRVPGNRSFFTLTEI--------IRFRCQ 2070
Query: 251 DGYDFL-------EVTGTEGSSL-WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQ 302
G+ + + G G L + P P I H S ++ G
Sbjct: 2071 PGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGE----HTLSHQDNFSPGQEVF 2126
Query: 303 YQVKKQIELK-SRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPD--PGIPERGKRLGSDF 359
Y + +L+ + + P D S + T C D +P L +
Sbjct: 2127 YSCEPSYDLRGAASLHCTPQGDWSPEAPRCTV-------KSCDDFLGQLPHGRVLLPLNL 2179
Query: 360 RLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSP 419
+LG+ V F C+EG+ L+G C+ ++ M A W+ PVC C P
Sbjct: 2180 QLGAKVSFVCDEGFRLKGRSASHCV-LAGMKALWNSSVPVCEQIFC-------------P 2225
Query: 420 NFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILT 479
N P N H + K I A + +RG +G+ +
Sbjct: 2226 N-PPAILNGRHTGTPFGDIPYGKEISYACDTHP-DRGMTFNLIGESS-----------IR 2272
Query: 480 GTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREG---SR 536
TS P Q +G SS + E +C P G G S
Sbjct: 2273 CTSDP--------------QGNGVWSSPAPRC--ELSVPAACPHPPKIQNGHYIGGHVSL 2316
Query: 537 FHHGDTLKFECQPAFELVGQKAITCQKNNQWS-----AKKPGCVFSCFFN 581
+ G T+ + C P + LVG+ I C WS K+ C F F N
Sbjct: 2317 YLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMN 2366
Score = 45.1 bits (105), Expect = 0.001
Identities = 154/721 (21%), Positives = 238/721 (33%), Gaps = 172/721 (23%)
Query: 305 VKKQIELKSRGVKL--MPSKDNSQKTSVLTQVGVSQGH-------NMCPDPGIPERGKRL 355
V + L SRG K+ + + + TS QVG+ G N C P + E G +
Sbjct: 1541 VTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV-ENGILV 1599
Query: 356 GSD---FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGP 412
+ F L V+F C G+ ++G +R+ C ++ W P C +R+C + P
Sbjct: 1600 SDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALN----KWEPELPSC-SRVC----QPP 1650
Query: 413 SGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTL---TVGDGGQDG 469
I+ + P DN + + + P +DL RG +L GD +
Sbjct: 1651 PEILHGEHTPSHQDNFSPGQEVFYSCEPG---------YDL-RGAASLHCTPQGDWSPEA 1700
Query: 470 DQKTVLYILTGTSVPDLIVSTNHQMWLL-----------------FQTDGSGSS----LG 508
+ V S D + H L F+ GS S +G
Sbjct: 1701 PRCAV------KSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVG 1754
Query: 509 FKA----SYEEIEQGSCGDPGIPAYGRREGS---RFHHGDTLKFECQP------AFELVG 555
++ S E C +P GR G+ +G + + C P F L+G
Sbjct: 1755 MRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIG 1814
Query: 556 QKAITCQK----NNQWSAKKPGCVFSC---------FFNFTSPSGVVLSPNYPEDYGNHL 602
+ I C N WS+ P C S F F SP+ + +P +
Sbjct: 1815 ESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNY 1874
Query: 603 HCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEA--PVLGTFSG-------NQL 653
C RP F+ I + ++D ++ P F+G Q
Sbjct: 1875 EC------RP-GYFGKMFS-ISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQF 1926
Query: 654 PSSIT-SSGHVARLEFQTDHSTGKRGFNITF----TTFRHNECPDPGVPVNGKRFGD--- 705
S++ S RL + G N+T+ C P NG + +
Sbjct: 1927 GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRT 1986
Query: 706 SLQLGSSISFLCDEGFLGTQ-----GSETITCVLKEGSV-VWNSAVLRCEAPCGGHLTSP 759
S G+ +++ C G G Q G +I C K+ V VW+S RC +
Sbjct: 1987 SFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEV 2046
Query: 760 SGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLI 819
I PG F+ L+ QPG+ + V T++ + + L
Sbjct: 2047 ENAIRVPGNRSFF--TLTEIIRFRCQPGFVM----------VGSHTVQCQTNGRWGPKLP 2094
Query: 820 GVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRH 879
Q P ++ + L SH D
Sbjct: 2095 HCSRVCQPPPEILHGEHTL--------SHQD----------------------------- 2117
Query: 880 GNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEA-LCGGFI-QGSSGTILS 937
+F G V +SC+ Y L L C P WS P C C F+ Q G +L
Sbjct: 2118 --NFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLL 2175
Query: 938 P 938
P
Sbjct: 2176 P 2176
Score = 40.4 bits (93), Expect = 0.031
Identities = 25/60 (41%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
Query: 138 TCGNPGRLPNGIQQGST-FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
+CG P NG+ +T G V YSCN GF L G TC S N+ TWD P C
Sbjct: 1906 SCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLV-SGNNVTWDKKAPIC 1964
Score = 38.1 bits (87), Expect = 0.15
Identities = 37/133 (27%), Positives = 49/133 (36%), Gaps = 17/133 (12%)
Query: 86 PPQPENLRTR-LTGFQLPATIVSAATTLSLRLISDYAVSA--QGFHATYEVLPSHT---- 138
PP P N +T Q+ + I + TT RLI + G A + P
Sbjct: 1457 PPDPVNGMVHVITDIQVGSRINYSCTT-GHRLIGHSSAECILSGNTAHWSTKPPICQRIP 1515
Query: 139 CGNPGRLPNG---IQQGSTFNLGDKVRYSCNLG------FFLEGHAVLTCHAGSENSATW 189
CG P + NG F+ G V Y CNLG F L G + C + + W
Sbjct: 1516 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1575
Query: 190 DFPLPSCRADDAC 202
P P C + C
Sbjct: 1576 SGPAPQCIIPNKC 1588
Score = 36.2 bits (82), Expect = 0.58
Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 9/67 (13%)
Query: 139 CGNPGRLPNGIQQGS---TFNLGDKVRYSCN------LGFFLEGHAVLTCHAGSENSATW 189
C +P +PNG G F G V Y+C+ F L G + + C + + + W
Sbjct: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
Query: 190 DFPLPSC 196
P P C
Sbjct: 481 SSPAPRC 487
Score = 36.2 bits (82), Expect = 0.58
Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 9/67 (13%)
Query: 139 CGNPGRLPNGIQQGS---TFNLGDKVRYSCN------LGFFLEGHAVLTCHAGSENSATW 189
C +P +PNG G F G V Y+C+ F L G + + C + + + W
Sbjct: 871 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 930
Query: 190 DFPLPSC 196
P P C
Sbjct: 931 SSPAPRC 937
Score = 36.2 bits (82), Expect = 0.58
Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 9/67 (13%)
Query: 139 CGNPGRLPNGIQQGS---TFNLGDKVRYSCN------LGFFLEGHAVLTCHAGSENSATW 189
C +P +PNG G F G V Y+C+ F L G + + C + + + W
Sbjct: 1321 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 1380
Query: 190 DFPLPSC 196
P P C
Sbjct: 1381 SSPAPRC 1387
Score = 35.8 bits (81), Expect = 0.76
Identities = 29/131 (22%), Positives = 49/131 (37%), Gaps = 18/131 (13%)
Query: 98 GFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRLPNGIQQGSTFN- 156
GF+L + VS + +R + + +V V C NP + NG G+
Sbjct: 1739 GFRLKGSSVSHCVLVGMRSLWNNSVP---------VCEHIFCPNPPAILNGRHTGTPSGD 1789
Query: 157 --LGDKVRYSCN------LGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRG 208
G ++ Y+C+ + F L G + + C + + W P P C G
Sbjct: 1790 IPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTP 1849
Query: 209 QSGIISSPHFP 219
+ +SP P
Sbjct: 1850 EQFPFASPTIP 1860
Score = 33.9 bits (76), Expect = 2.9
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 2/67 (2%)
Query: 132 EVLPSHTCGNPGRLPNGIQQGST-FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWD 190
+V +C P NG+ T +G ++ YSC G L GH+ C S N+A W
Sbjct: 547 DVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNAAHWS 605
Query: 191 FPLPSCR 197
P C+
Sbjct: 606 TKPPICQ 612
Score = 33.9 bits (76), Expect = 2.9
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 2/67 (2%)
Query: 132 EVLPSHTCGNPGRLPNGIQQGST-FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWD 190
+V +C P NG+ T +G ++ YSC G L GH+ C S N+A W
Sbjct: 997 DVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNAAHWS 1055
Query: 191 FPLPSCR 197
P C+
Sbjct: 1056 TKPPICQ 1062
Score = 33.9 bits (76), Expect = 2.9
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 2/67 (2%)
Query: 132 EVLPSHTCGNPGRLPNGIQQGST-FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWD 190
+V +C P NG+ T +G ++ YSC G L GH+ C S N+A W
Sbjct: 1447 DVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNTAHWS 1505
Query: 191 FPLPSCR 197
P C+
Sbjct: 1506 TKPPICQ 1512
Score = 33.9 bits (76), Expect = 2.9
Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 5/59 (8%)
Query: 883 FYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSC-----EALCGGFIQGSSGTIL 936
++ G VT C+ GYTL +C+ + +W L C +AL G + G+ IL
Sbjct: 2378 YHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTSRTHDALIVGTLSGTIFFIL 2436
Score = 33.1 bits (74), Expect = 5.0
Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 138 TCGNPGRLPNG---IQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLP 194
+C NP NG + +G F G +++YSC G+ L G + TC S ++ WD P
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQF--GSQIKYSCTKGYRLIGSSSATCII-SGDTVIWDNETP 159
Query: 195 SC 196
C
Sbjct: 160 IC 161
Score = 32.7 bits (73), Expect = 6.5
Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 7/58 (12%)
Query: 142 PGRLPNGI---QQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
P + NGI S F+L + V + C GF ++G + C A ++ W+ LPSC
Sbjct: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPSC 293
Score = 32.7 bits (73), Expect = 6.5
Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 7/58 (12%)
Query: 142 PGRLPNGI---QQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
P + NGI S F+L + V + C GF ++G + C A ++ W+ LPSC
Sbjct: 690 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPSC 743
Score = 32.7 bits (73), Expect = 6.5
Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 7/58 (12%)
Query: 142 PGRLPNGI---QQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
P + NGI S F+L + V + C GF ++G + C A ++ W+ LPSC
Sbjct: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPSC 1193
>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
Length = 2039
Score = 282 bits (721), Expect = 5e-75
Identities = 313/1226 (25%), Positives = 457/1226 (37%), Gaps = 226/1226 (18%)
Query: 2121 QECPDPEPFANGIVRG-AGYNVGQSVTFECLPGYQLTGHPVLTC-QHGTNRNWDHPLPKC 2178
+ C P NG+V VG + + C G++L GH C G +W P C
Sbjct: 552 KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Query: 2179 E-VPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPS----- 2232
+ +PCG T +NG S + + S V G G R L+ EPS
Sbjct: 612 QRIPCGLPPTIANGDFISTNRENFHYGS---VVTYRCNPGSGGRKVFELVG-EPSIYCTS 667
Query: 2233 -GDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPL 2291
D + IW GP AP+ +
Sbjct: 668 NDDQVGIWSGP---APQCII---------------------------------------P 685
Query: 2292 TKCPPPTILPNAEVVTENEE-FNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPI 2350
KC PP + N +V++N F++ ++V +RC PGF + G + C+ ++E P
Sbjct: 686 NKCTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ--ALNKWEPELPS 742
Query: 2351 CEVHC--PTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQY 2408
C C P + L + T PG F +C EP Y++
Sbjct: 743 CSRVCQPPPDVLHAERTQRDKDNFSPGQ-EVFYSC------EPGYDLR------------ 783
Query: 2409 DEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYC 2468
G + + G++S +AP C
Sbjct: 784 ----------GAASMRCTPQGDWSP------------------------------AAPTC 803
Query: 2469 SLPRAP------LHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEA 2522
+ L+G +L + Q G + F C+ G++L G S + C LW+ +
Sbjct: 804 EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGME-SLWNSS 862
Query: 2523 IPLCQALSCGLPEAPKNGMVFGKEYTV---GTKAMYSCS----EGYHLQAGAEATAECLD 2575
+P+C+ + C P NG GK V G Y+C G E+T C
Sbjct: 863 VPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTS 922
Query: 2576 ----TGLWSNRNVPPQCVPV---TCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGY 2628
G+WS+ P+C + PD + + + + L C P Y
Sbjct: 923 DPQGNGVWSSP--APRCGILGHCQAPDHFLFAKLKTQTNA---SDFPIGTSLKYECRPEY 977
Query: 2629 YYTGQRV-IRCQANGKWSLGDSTPTCRIISCGELPIPPNG--HRIGTLSVYGATAIFSCN 2685
Y G+ I C N WS C+ SC P P NG H I + V G+ +SC
Sbjct: 978 Y--GRPFSITCLDNLVWS--SPKDVCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCT 1032
Query: 2686 SGYTLVGSRVRECMANGL---WSGSEVRCLAGHCGTPEPIVNGHI---NGENYSYRGSVV 2739
+G+ L+G EC+ +G WS C CG P I NG N EN+ Y V
Sbjct: 1033 TGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVT 1092
Query: 2740 YQCNAG------FRLIGMSVRICQQDHH----WSGKTPFCVLVSCGHPGSPPHSQMSGDS 2789
Y+CN G F L+G C + WSG P C++ + P + + + D+
Sbjct: 1093 YRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDN 1152
Query: 2790 ---YTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIR 2846
+++ VV + C + G C W LP CS VC P HG
Sbjct: 1153 RSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSR----VCQPPPEILHGEH 1208
Query: 2847 LG---DSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGN-PGTPSNA 2902
D+F PG + +SCE G+ LRG++ C G WS P C V SC + G +
Sbjct: 1209 TPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHG 1268
Query: 2903 RVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNG---TWTGSDPECLVINCGDPGIPA 2959
RV+F L + + + C EG+ G HC + G W S P C I C +P
Sbjct: 1269 RVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAIL 1328
Query: 2960 NGLRLG---NDFRYNKTVTYQCVP----GYMMESHRVSVLSCTKD----RTWNGTKPVC- 3007
NG G D Y K ++Y C P G S + CT D W+ P C
Sbjct: 1329 NGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCE 1388
Query: 3008 ---KALMCKPPPLIPNGK----VVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTG 3060
+A CK P P + +F G+S+ Y C GY + ++ +C N W+
Sbjct: 1389 LSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSI-SCLENLVWSS 1447
Query: 3061 ELPQCFPVFCGDPGVPSRGR-REDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDG---TW 3116
C CG P P G + + S+V++SC+ L+GSP C G TW
Sbjct: 1448 VEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW 1507
Query: 3117 SGTQPSCIDPTLTTCADPGVPQFG--IQNNSQGYQVGSTVLFRCQKG------YLLQGST 3168
P C + +C P G NN + G+ V ++C G + L G
Sbjct: 1508 DKKAPIC---EIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGER 1564
Query: 3169 TRTCLPN----LTWSGTPPDCV-PHHCRQPETPTHANV-GALDLPSMGYTLIYSCQEGFS 3222
+ C WS PP C+ + C PE V G ++ + + CQ GF
Sbjct: 1565 SIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFV 1624
Query: 3223 LKGGSEHRTCKADGSWTGKPPICLEV 3248
+ GS C+ +G W K P C V
Sbjct: 1625 MV-GSHTVQCQTNGRWGPKLPHCSRV 1649
Score = 281 bits (718), Expect = 1e-74
Identities = 473/2021 (23%), Positives = 719/2021 (35%), Gaps = 383/2021 (18%)
Query: 1384 SCNDPGIPQNGS-RSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCI 1442
SC +P P NG + G + C GY L GS+ +C+ + W P C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 1443 A-PCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHI 1501
PCG T +G +S N E + G ++ +P VF + EP ++
Sbjct: 163 RIPCGLPPTITNGDFISTNR-ENFHYGSVVTYRC--NPGSGGRKVFELVG-EPS---IYC 215
Query: 1502 YDGRDSLSPLIGSFYGSQLP----------GRIESSSNSLFLAFRSDASVSNAGFVIDYT 1551
D + G +P G + S + SLF GFV+
Sbjct: 216 TSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVM--- 272
Query: 1552 ENPRES------------------CFDPGSIKNGTRVGSD---LKLGSSVTYYCHGGYEV 1590
+ PR C P + + R D G V Y C GY++
Sbjct: 273 KGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDL 332
Query: 1591 EGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQYVGS--DGVVLSP-NYPQNYTSGQICLY 1647
G +++ C P G W+ P C ++G +G VL P N +C
Sbjct: 333 RGAASMRCT--PQGD--WSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDE 388
Query: 1648 FVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLI 1707
+ + A + N V V + S + +G HTG+ L + + +
Sbjct: 389 GFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIP-NGRHTGKPLEVFPFGKT-V 446
Query: 1708 KFSAKGLAPARG--FHFVYQAVPR-TSATQCSSV---PEPRYG----------------- 1744
++ P RG F + ++ R TS Q + V P PR G
Sbjct: 447 NYTCDP-HPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLK 505
Query: 1745 -KRLGSDFSVGAIVRFECNSGYALQGSP-EIECLPVPGALAQWNVSAPTCVVPCGGNLTE 1802
+ SDF +G +++EC Y G P I CL W+ C
Sbjct: 506 TQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDN----LVWSSPKDVC---------- 549
Query: 1803 RRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTM 1862
+R + +P P+P ++ + IQV S +
Sbjct: 550 KRKSCKTP--PDPVNGMVHVI----------TDIQVGSRI-------------------- 577
Query: 1863 LGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNG--VK 1920
++S TT L+ +S + L S +AA + + C P +NG +
Sbjct: 578 --NYSCTTGHRLIGHSSAECIL------SGNAAHWSTKPPICQRIPCGLPPTIANGDFIS 629
Query: 1921 TG-ERYLVNDVVSFQCEPG------YALQGHAHISCMPGT--VRRWNYPPPLCIAQCGGT 1971
T E + VV+++C PG + L G I C V W+ P P CI T
Sbjct: 630 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 689
Query: 1972 VEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYET 2031
+E IL + N + + F +P + GP
Sbjct: 690 PPNVENGILVSDNRSLFSLN-----------------EVVEFRCQPGF----VMKGPRRV 728
Query: 2032 SRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSFLRGFDL 2091
ELPS V H++ +Q Q++ YS + G+DL
Sbjct: 729 KCQALNKWEPELPSCSRVCQPPPDV-LHAERTQRDKDNFSPGQEVFYSCE-----PGYDL 782
Query: 2092 SELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRG-----AGYNVGQSVT 2146
TP D P E++ C D F ++ G +G V
Sbjct: 783 RGAASMRCTPQ------GDWSPAAPTCEVKSCDD---FMGQLLNGRVLFPVNLQLGAKVD 833
Query: 2147 FECLPGYQLTGHPVLTCQ-HGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSPYSSS 2205
F C G+QL G C G W+ +P CE ++ P P +
Sbjct: 834 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE------------QIFCPSPPVIPNGR 881
Query: 2206 QDCVWLITVPIGHGVRLNLS-----------------LLQTEPSGDFITIWDGPQQTAPR 2248
L P G V ++P G+ +W P APR
Sbjct: 882 HTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGN--GVWSSP---APR 936
Query: 2249 LGVFTRSMAK--------KTVQSSSNQVL---LKFH-RDAATGGIFAIAFS-----AYPL 2291
G+ A KT ++S+ + LK+ R G F+I + P
Sbjct: 937 CGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPK 996
Query: 2292 TKC-------PPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKL-GTYLQ 2343
C PP + V+T+ +G + Y C G L+G+ C L G
Sbjct: 997 DVCKRKSCKTPPDPVNGMVHVITD---IQVGSRINYSCTTGHRLIGHSSAECILSGNTAH 1053
Query: 2344 FEGPPPICEVHCPTNELLTDSTGVILSQS----YPGSYPQFQTCSWLVRVEPDYNISLTV 2399
+ PPIC+ P T + G +S + + GS ++ C+ R + +
Sbjct: 1054 WSTKPPICQ-RIPCGLPPTIANGDFISTNRENFHYGSVVTYR-CNLGSRGRKVFELVGEP 1111
Query: 2400 EYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYL------------- 2446
+ + D+ I+ GP+ Q + + I+ S + S++
Sbjct: 1112 SIYCTSND-DQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGF 1170
Query: 2447 -----RWSSDHAYNRKGFKIRYSAPYCSLPRAPLHGFILG--QTSTQPGGSIHFGCNAGY 2499
R A N+ ++ + C P LHG Q + PG + + C GY
Sbjct: 1171 VMKGPRRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGY 1230
Query: 2500 RLVGHSMAICTRHPQGYHLWSEAIPLCQALSCG--LPEAPKNGMVFGKEYTVGTKAMYSC 2557
L G + CT PQG WS P C SC L + P ++F +G K + C
Sbjct: 1231 DLRGAASLHCT--PQGD--WSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVC 1286
Query: 2558 SEGYHLQAGAEATAECLDTG---LWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQY 2614
EG+ L+ + + C+ G LW+N P C + CP+ +I +GR
Sbjct: 1287 DEGFRLKGSS--VSHCVLVGMRSLWNNS--VPVCEHIFCPNPPAIL--NGRHTGTPSGDI 1340
Query: 2615 QFQAQLMLICDPG------YYYTGQRVIRCQA----NGKWSLGDSTPTCRI-ISCGELPI 2663
+ ++ CDP + G+ IRC + NG WS P C + + G
Sbjct: 1341 PYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWS--SPAPRCELSVRAGHCKT 1398
Query: 2664 PPN-GHRIGTLSV------YGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHC 2716
P T+ + G + + C GY + C+ N +WS E C C
Sbjct: 1399 PEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSI-SCLENLVWSSVEDNCRRKSC 1457
Query: 2717 GTPEPIVNG--HINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHH---WSGKTPFCVL 2771
G P NG HIN + + +V Y CN GFRLIG C + W K P C +
Sbjct: 1458 GPPPEPFNGMVHINTDT-QFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEI 1516
Query: 2772 VSCGHPGSPPHSQMSGDSYTV-------GAVVRYSCI----GKRT--LVGNSTRMCGLD- 2817
+SC PP + +GD Y+ G VV Y C G++ LVG + C
Sbjct: 1517 ISC----EPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKD 1572
Query: 2818 ---GHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDS---FDPGTVMRFSCEAGHVLRGSS 2871
G W+ P C T+ C P + + IR+ + F ++RF C+ G V+ GS
Sbjct: 1573 DQVGVWSSPPPRCISTNK--CTAPEVE-NAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSH 1629
Query: 2872 ERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFS--SSIVYECREGYYATGL 2929
CQ NG W P C + C P + S FS + Y C Y G
Sbjct: 1630 TVQCQTNGRWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGA 1688
Query: 2930 LSRHCSVNGTWTGSDPECLVINCGD--PGIPANGLRLGNDFRYNKTVTYQCVPGYMMESH 2987
S HC+ G W+ P C V +C D +P + L + + V++ C G+ ++
Sbjct: 1689 ASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGR 1748
Query: 2988 RVS--VLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGS---DFMWGSSVTYAC---- 3038
S VL+ K WN + PVC+ + C PP I NG+ G+ D +G ++YAC
Sbjct: 1749 SASHCVLAGMK-ALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHP 1807
Query: 3039 -------LEGYQLSLPAVFTCEGNGSWTGELPQC---FPVFCGDPGVPSRGRREDRGFSY 3088
L G + S+ +GNG W+ P+C P C P G S
Sbjct: 1808 DRGMTFNLIG-ESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSL 1866
Query: 3089 R---SSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNN- 3144
++S+ C P +LVG FC G WS C + C+ P + GI
Sbjct: 1867 YLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKE---VNCSFP-LFMNGISKEL 1922
Query: 3145 --SQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPP 3183
+ Y G V +C+ GY L+GS C + W PP
Sbjct: 1923 EMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWD--PP 1961
Score = 268 bits (685), Expect = 7e-71
Identities = 283/1093 (25%), Positives = 416/1093 (38%), Gaps = 211/1093 (19%)
Query: 2121 QECPDPEPFANGIVRG-AGYNVGQSVTFECLPGYQLTGHPVLTC-QHGTNRNWDHPLPKC 2178
+ C P NG+V VG + + C G++L GH C G +W P C
Sbjct: 1002 KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPIC 1061
Query: 2179 E-VPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVR-LNLSLLQTEPS---- 2232
+ +PCG T +NG S + + S ++T G R + L EPS
Sbjct: 1062 QRIPCGLPPTIANGDFISTNRENFHYGS-----VVTYRCNLGSRGRKVFELVGEPSIYCT 1116
Query: 2233 --GDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYP 2290
D + IW GP AP+ +
Sbjct: 1117 SNDDQVGIWSGP---APQCII--------------------------------------- 1134
Query: 2291 LTKCPPPTILPNAEVVTENEE-FNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPP 2349
KC PP + N +V++N F++ ++V +RC PGF + G + C+ ++E P
Sbjct: 1135 PNKCTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ--ALNKWEPELP 1191
Query: 2350 ICEVHC-PTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQY 2408
C C P E+L ++ F +C EP Y++
Sbjct: 1192 SCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSC------EPGYDLR------------ 1233
Query: 2409 DEFEIFDGPSGQSPLLKALSGNYS--APLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAP 2466
G + L G++S AP S +
Sbjct: 1234 ----------GAASLHCTPQGDWSPEAPRCAVKSCDDF---------------------- 1261
Query: 2467 YCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLC 2526
L + P HG +L + Q G + F C+ G+RL G S++ C LW+ ++P+C
Sbjct: 1262 ---LGQLP-HGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMR-SLWNNSVPVC 1316
Query: 2527 QALSCGLPEAPKNGMVFGK---EYTVGTKAMYSCS----EGYHLQAGAEATAECLD---- 2575
+ + C P A NG G + G + Y+C G E+T C
Sbjct: 1317 EHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHG 1376
Query: 2576 TGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRL------------IFETQYQFQAQLMLI 2623
G+WS+ P+C +SV G + I + ++ L
Sbjct: 1377 NGVWSSP--APRC---------ELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYE 1425
Query: 2624 CDPGYYYTGQRV-IRCQANGKWSLGDSTPTCRIISCGELPIPPNGH-RIGTLSVYGATAI 2681
C PGY+ G+ I C N WS + CR SCG P P NG I T + +G+T
Sbjct: 1426 CRPGYF--GKMFSISCLENLVWSSVEDN--CRRKSCGPPPEPFNGMVHINTDTQFGSTVN 1481
Query: 2682 FSCNSGYTLVGSRVRECMANG---LWSGSEVRCLAGHCGTPEPIVNGHINGENYS--YRG 2736
+SCN G+ L+GS C+ +G W C C P I NG N + + G
Sbjct: 1482 YSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNG 1541
Query: 2737 SVV-YQCNAG------FRLIGMSVRIC----QQDHHWSGKTPFCVLVS-CGHPGSPPHSQ 2784
+VV YQC+ G F L+G C Q WS P C+ + C P +
Sbjct: 1542 TVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIR 1601
Query: 2785 MSGDS--YTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPA 2842
+ G+ +T+ ++R+ C +VG+ T C +G W LPHCS VC P
Sbjct: 1602 VPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSR----VCQPPPEIL 1657
Query: 2843 HG---IRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGN-PGT 2898
HG + D+F PG + +SCE + LRG++ C G WS P C V SC + G
Sbjct: 1658 HGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQ 1717
Query: 2899 PSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNG---TWTGSDPECLVINCGDP 2955
+ RV+ L + + + C EG+ G + HC + G W S P C I C +P
Sbjct: 1718 LPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNP 1777
Query: 2956 GIPANGLRLG---NDFRYNKTVTYQCVP----GYMMESHRVSVLSCTKD----RTWNGTK 3004
NG G D Y K ++Y C G S + CT D W+
Sbjct: 1778 PAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPA 1837
Query: 3005 PVCKALM---CKPPPLIPNGKVVG---SDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSW 3058
P C+ + C PP I NG +G S ++ G +++Y C GY L C G W
Sbjct: 1838 PRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIW 1897
Query: 3059 TGELPQCFPVFCGDP----GVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDG 3114
+ C V C P G+ S+ + + Y V+ C L GSP CQ+D
Sbjct: 1898 SQLDHYCKEVNCSFPLFMNGI-SKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADD 1956
Query: 3115 TWSGTQPSCIDPT 3127
W C T
Sbjct: 1957 RWDPPLAKCTSRT 1969
Score = 260 bits (665), Expect = 1e-68
Identities = 309/1254 (24%), Positives = 447/1254 (35%), Gaps = 222/1254 (17%)
Query: 2139 YNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCG--------------- 2183
+++ + V F C PG+ + G + CQ W+ LP C C
Sbjct: 256 FSLNEVVEFRCQPGFVMKGPRRVKCQ--ALNKWEPELPSCSRVCQPPPDVLHAERTQRDK 313
Query: 2184 GNITSSNGTVYS--PGFPSPYSSSQDCV----WLITVPIGHGVRLNLSLLQTEPSGDFIT 2237
N + YS PG+ ++S C W P + + DF+
Sbjct: 314 DNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPT----------CEVKSCDDFMG 363
Query: 2238 IWDGPQQTAP---RLGVFTRSMAKKTVQ---SSSNQVLLKFHRDAATGGIFAIAFSAYPL 2291
+ P +LG + + Q SS++ +L G+ ++ S+ P+
Sbjct: 364 QLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVL--------AGMESLWNSSVPV 415
Query: 2292 TK---CPPPTILPNAEVVTEN-EEFNIGDIVRYRCLP------GFTLVGNEILTCKLGTY 2341
+ CP P ++PN + E F G V Y C P F L+G + C
Sbjct: 416 CEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQ 475
Query: 2342 LQ--FEGPPPICEV--HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISL 2397
+ P P C + HC PD+
Sbjct: 476 GNGVWSSPAPRCGILGHCQA---------------------------------PDH---- 498
Query: 2398 TVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRK 2457
FL K + D P G S + Y P +T N V WSS ++
Sbjct: 499 ----FLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLV---WSSPKDVCKR 551
Query: 2458 GFKIRYSAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYH 2517
C P P++G + T Q G I++ C G+RL+GHS A C H
Sbjct: 552 --------KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAH 603
Query: 2518 LWSEAIPLCQALSCGLPEAPKNGMVFG---KEYTVGTKAMYSCSEG------YHL--QAG 2566
WS P+CQ + CGLP NG + + G+ Y C+ G + L +
Sbjct: 604 -WSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPS 662
Query: 2567 AEATAECLDTGLWSNRNVPPQC-VPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICD 2625
T+ G+WS PQC +P C + +VE+G + + + C
Sbjct: 663 IYCTSNDDQVGIWS--GPAPQCIIPNKC---TPPNVENGILVSDNRSLFSLNEVVEFRCQ 717
Query: 2626 PGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLS-----VYGATA 2680
PG+ G R ++CQA KW P+C + P P H T G
Sbjct: 718 PGFVMKGPRRVKCQALNKWE--PELPSCSRVC---QPPPDVLHAERTQRDKDNFSPGQEV 772
Query: 2681 IFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGE-----NYSYR 2735
+SC GY L G+ C G WS + C C + + +NG N
Sbjct: 773 FYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSC---DDFMGQLLNGRVLFPVNLQLG 829
Query: 2736 GSVVYQCNAGFRLIGMSVRIC---QQDHHWSGKTPFCVLVSCGHPGSPPHSQMSG---DS 2789
V + C+ GF+L G S C + W+ P C + C P P+ + +G +
Sbjct: 830 AKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEV 889
Query: 2790 YTVGAVVRYSCI------GKRTLVGNSTRMCGLD----GHWTGSLPHCSGTSVGVCGDPG 2839
+ G V Y+C L+G ST C D G W+ P C G+ G
Sbjct: 890 FPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC-----GILGHCQ 944
Query: 2840 IPAHGI-------RLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVIS 2892
P H + F GT +++ C + R S TC N WS + C S
Sbjct: 945 APDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFS-ITCLDNLVWSSPKDVCKRKS 1003
Query: 2893 CGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGT---WTGSDPECLV 2949
C P P N V + S I Y C G+ G S C ++G W+ P C
Sbjct: 1004 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQR 1063
Query: 2950 INCGDPGIPANGLRLG---NDFRYNKTVTYQCVPG----YMMESHRVSVLSCTKD----R 2998
I CG P ANG + +F Y VTY+C G + E + CT +
Sbjct: 1064 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVG 1123
Query: 2999 TWNGTKPVCKALMCKPPPLIPNGKVVGSD---FMWGSSVTYACLEGYQLSLPAVFTCEGN 3055
W+G P C PP + NG +V + F V + C G+ + P C+
Sbjct: 1124 IWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 1183
Query: 3056 GSWTGELPQCFPVFCGDPGVPSRGRR---EDRGFSYRSSVSFSCHPPLVLVGSPRRFCQS 3112
W ELP C V C P G FS V +SC P L G+ C
Sbjct: 1184 NKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP 1242
Query: 3113 DGTWSGTQPSCIDPTLTTCAD-PGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRT 3171
G WS P C + +C D G G Q+G+ V F C +G+ L+GS+
Sbjct: 1243 QGDWSPEAPRC---AVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSH 1299
Query: 3172 CL---PNLTWSGTPPDCVPHHCRQPE---TPTHANVGALDLPSMGYTLIYSCQE------ 3219
C+ W+ + P C C P H + D+P G + Y+C
Sbjct: 1300 CVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIP-YGKEISYTCDPHPDRGM 1358
Query: 3220 GFSLKGGSEHRTCKAD----GSWTGKPPICLEVRPSGRPINTAREPPLTQALIP 3269
F+L G S R C +D G W+ P C E+ T + P IP
Sbjct: 1359 TFNLIGESTIR-CTSDPHGNGVWSSPAPRC-ELSVRAGHCKTPEQFPFASPTIP 1410
Score = 248 bits (633), Expect = 7e-65
Identities = 257/980 (26%), Positives = 365/980 (37%), Gaps = 135/980 (13%)
Query: 2346 GPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSE 2405
GPP C LL V++ + P ++ Q WL P +LT E+
Sbjct: 13 GPPAPGLPFCCGGSLLA----VVVLLALPVAWGQCNAPEWLPFARPT---NLTDEFEFPI 65
Query: 2406 KQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465
Y +E G SG+ P + NSV+ G K R
Sbjct: 66 GTYLNYECRPGYSGR-------------PFSIICLKNSVWT-----------GAKDRCRR 101
Query: 2466 PYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPL 2525
C P P++G + Q G I + C GYRL+G S A C +W P+
Sbjct: 102 KSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTV-IWDNETPI 160
Query: 2526 CQALSCGLPEAPKNGMVFG---KEYTVGTKAMYSCSEG------YHL--QAGAEATAECL 2574
C + CGLP NG + + G+ Y C+ G + L + T+
Sbjct: 161 CDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDD 220
Query: 2575 DTGLWSNRNVPPQC-VPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQ 2633
G+WS PQC +P C + +VE+G + + + C PG+ G
Sbjct: 221 QVGIWS--GPAPQCIIPNKC---TPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 275
Query: 2634 RVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLS-----VYGATAIFSCNSGY 2688
R ++CQA KW P+C + P P H T G +SC GY
Sbjct: 276 RRVKCQALNKWE--PELPSCSRVC---QPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY 330
Query: 2689 TLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGE-----NYSYRGSVVYQCN 2743
L G+ C G WS + C C + + +NG N V + C+
Sbjct: 331 DLRGAASMRCTPQGDWSPAAPTCEVKSC---DDFMGQLLNGRVLFPVNLQLGAKVDFVCD 387
Query: 2744 AGFRLIGMSVRIC---QQDHHWSGKTPFCVLVSCGHPGSPPHSQMSG---DSYTVGAVVR 2797
GF+L G S C + W+ P C + C P P+ + +G + + G V
Sbjct: 388 EGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVN 447
Query: 2798 YSCI------GKRTLVGNSTRMCGLD----GHWTGSLPHCSGTSVGVCGDPGIPAHGI-- 2845
Y+C L+G ST C D G W+ P C G+ G P H +
Sbjct: 448 YTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC-----GILGHCQAPDHFLFA 502
Query: 2846 -----RLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPS 2900
F GT +++ C + R S TC N WS + C SC P P
Sbjct: 503 KLKTQTNASDFPIGTSLKYECRPEYYGRPFS-ITCLDNLVWSSPKDVCKRKSCKTPPDPV 561
Query: 2901 NARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGT---WTGSDPECLVINCGDPGI 2957
N V + S I Y C G+ G S C ++G W+ P C I CG P
Sbjct: 562 NGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPT 621
Query: 2958 PANGLRLG---NDFRYNKTVTYQCVPG----YMMESHRVSVLSCTKD----RTWNGTKPV 3006
ANG + +F Y VTY+C PG + E + CT + W+G P
Sbjct: 622 IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 681
Query: 3007 CKALMCKPPPLIPNGKVVGSD---FMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELP 3063
C PP + NG +V + F V + C G+ + P C+ W ELP
Sbjct: 682 CIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP 741
Query: 3064 QCFPVFCGDPGV--PSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQP 3121
C V P V R +R+ FS V +SC P L G+ C G WS P
Sbjct: 742 SCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAP 801
Query: 3122 SCIDPTLTTCAD-PGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCL---PNLT 3177
+C + +C D G G Q+G+ V F C +G+ L+GS+ C+
Sbjct: 802 TC---EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 858
Query: 3178 WSGTPPDCVPHHCRQPET-PTHANVG-ALDLPSMGYTLIYSCQ------EGFSLKGGSEH 3229
W+ + P C C P P + G L++ G + Y+C F L G S
Sbjct: 859 WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTI 918
Query: 3230 RTCKAD----GSWTGKPPIC 3245
R C +D G W+ P C
Sbjct: 919 R-CTSDPQGNGVWSSPAPRC 937
Score = 143 bits (360), Expect = 3e-33
Identities = 437/2082 (20%), Positives = 703/2082 (33%), Gaps = 440/2082 (21%)
Query: 687 RHNECPDPGVPVNGK-RFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAV 745
R C +P PVNG +Q GS I + C +G+ GS + TC++ +V+W++
Sbjct: 100 RRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYR-LIGSSSATCIISGDTVIWDNET 158
Query: 746 LRCE-APCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYD 804
C+ PCG T +G +S F+ ++ PG + F+ Y
Sbjct: 159 PICDRIPCGLPPTITNGDFISTNRENFHYGSVV---TYRCNPGSGGRKVFELVGEPSIYC 215
Query: 805 TLEVRDGRTYS--APLIGVYHGTQVPQ----FLISTSNYLYLLFSTDKSHSDIGFQLR-Y 857
T +S AP + + P L+S + L+ L + GF ++
Sbjct: 216 TSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 275
Query: 858 ETITLQSDHCLDPGIP---------------VNGQRHGNDFYVGALVTFSCDSGYTLSDG 902
+ Q+ + +P +P QR ++F G V +SC+ GY L
Sbjct: 276 RRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
Query: 903 EPLECEPNFQWSRALPSCEA-LCGGFI-QGSSGTILSPGFPDFYPNNLNCTWIIETSHGK 960
+ C P WS A P+CE C F+ Q +G +L P
Sbjct: 336 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP---------------------- 373
Query: 961 GVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDF 1020
+L+ G + + G QL GS + AG+ + + V
Sbjct: 374 --------VNLQLGAKVDFVCDEGF------QLKGSSASYCVLAGMESLWNSSVPVCEQI 419
Query: 1021 SMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQ---FGVGDTLTFSCFP------GYRL 1071
C P V G F G T+ ++C P + L
Sbjct: 420 F-----------------CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDL 462
Query: 1072 EGTARITCLGGRR--RLWSSPLPRC--VAEC--------GNSVTGTQGTLLSPNFPVNYN 1119
G + I C + +WSSP PRC + C T T + +FP+ +
Sbjct: 463 IGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNAS----DFPIGTS 518
Query: 1120 NNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGVFS--HSEMMGVTL 1177
+EC +P L + S DV K + G+ +G +
Sbjct: 519 LKYECRPEYYGRPFSITCLDNLVWS-SPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRI 577
Query: 1178 N-STSSSLWLDFITDAENTSKGFELHFSS----FELIKCEDPGTPKFG--YKVHDEGHFA 1230
N S ++ L + AE G H+S+ + I C P T G + E
Sbjct: 578 NYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHY 637
Query: 1231 GSSVSFSCDPG------YSLRGSEELLCLSGERRT--WDRPLPTCVAECGGTVRGEVSGQ 1282
GS V++ C+PG + L G + C S + + W P P C+ T +G
Sbjct: 638 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGI 697
Query: 1283 VLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVH-DVLRIWDGPVESGVLLKE 1341
++S +LN + + G F++ V L W+ + S + +
Sbjct: 698 LVSDNRSL---FSLNEVVEFRCQPG------FVMKGPRRVKCQALNKWEPELPSCSRVCQ 748
Query: 1342 LSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVS---TATSCNDPGIPQNGSRSG 1398
L + F++ + G+ ++ + S T P P +S
Sbjct: 749 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSC 808
Query: 1399 DSW---------------EAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIA 1443
D + + G F CD G+ L+GS+ CV W S P C
Sbjct: 809 DDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQ 868
Query: 1444 P-CGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIY 1502
C P+G E +P GK ++ PD +D +
Sbjct: 869 IFCPSPPVIPNGRHTGKPL-EVFPFGKAVNYTCDPHPD-----------RGTSFDLIGES 916
Query: 1503 DGRDSLSPLIGSFYGSQLP-----GRIESSSNSLFLAFRSDASVSN--AGFVIDYTENP- 1554
R + P + S P G ++ + LF ++ + S+ G + Y P
Sbjct: 917 TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPE 976
Query: 1555 ------------------------RESCFDPGSIKNG-TRVGSDLKLGSSVTYYCHGGYE 1589
R+SC P NG V +D+++GS + Y C G+
Sbjct: 977 YYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHR 1036
Query: 1590 VEGTSTLSCILGPDGKPVWNNPRPVC-TAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYF 1648
+ G S+ CIL W+ P+C PCG ++G +S N +N+ G + Y
Sbjct: 1037 LIGHSSAECILS-GNTAHWSTKPPICQRIPCGLPPTIANGDFISTN-RENFHYGSVVTYR 1094
Query: 1649 VTV----PKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSL------SGSHTGESLP 1698
+ K + + G+ + + T+ +D V + G + + + +G ++
Sbjct: 1095 CNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRS 1154
Query: 1699 LATSNQVLIKFSAKGLAPARGFHFVYQAVPR------TSATQCSSVPEPRYGKRLGS--- 1749
L + N+V+ G QA+ + + + C PE +G+ S
Sbjct: 1155 LFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQD 1214
Query: 1750 DFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVV-PCGGNLTE-RRGTI 1807
+FS G V + C GY L+G+ + C P W+ AP C V C L + G +
Sbjct: 1215 NFSPGQEVFYSCEPGYDLRGAASLHCTP----QGDWSPEAPRCAVKSCDDFLGQLPHGRV 1270
Query: 1808 LSPGFPEPYLN-SLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSF 1866
L P LN L V EG ++ VS SL +N+V +
Sbjct: 1271 LFP------LNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSL-----WNNSVPVCEHI 1319
Query: 1867 SGTTVPALLNSTSNQL---YLHFYSDISVS-------AAGFHLEYKTV----------GL 1906
PA+LN + + +IS + F+L ++ G+
Sbjct: 1320 FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGV 1379
Query: 1907 SSCPEP----AVPSNGVKTGERY-------LVNDV-------VSFQCEPGYALQGHAHIS 1948
S P P +V + KT E++ +ND ++++C PGY + + IS
Sbjct: 1380 WSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFS-IS 1438
Query: 1949 CMPGTVRRWNYPPPLCIAQ-CGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAH 2007
C+ V W+ C + CG E G++ I FG+
Sbjct: 1439 CLENLV--WSSVEDNCRRKSCGPPPEPFNGMV-----------------HINTDTQFGST 1479
Query: 2008 IQFLNFSTEPNHDYIEIRNGPYETSRMMGR---FSGSELPSSLLSTSHETTVYFHSDHSQ 2064
+ N+S ++ + P T + G + ++S T+ +S
Sbjct: 1480 V---NYSC---NEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSN 1533
Query: 2065 NRPGFKLEYQDLTYSHQISSFLRGFDLSELERTNS---TPPVAASYVWDLDPGCEAYELQ 2121
NR F + ++Q + G L EL S T VW P
Sbjct: 1534 NRTSF---HNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWS-SPPPRCISTN 1589
Query: 2122 ECPDPEPFANGIVRGAG----YNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPK 2177
+C PE +R G + + + + F C PG+ + G + CQ TN W LP
Sbjct: 1590 KCTAPE--VENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQ--TNGRWGPKLPH 1645
Query: 2178 CEVPC-------GGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTE 2230
C C G T S+ +SPG YS + +R + L
Sbjct: 1646 CSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEP----------SYDLR-GAASLHCT 1694
Query: 2231 PSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYP 2290
P GD+ APR V +S Q +VLL P
Sbjct: 1695 PQGDW-------SPEAPRCTV--KSCDDFLGQLPHGRVLL-------------------P 1726
Query: 2291 LTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKL-GTYLQFEGPPP 2349
L +G V + C GF L G C L G + P
Sbjct: 1727 L-------------------NLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVP 1767
Query: 2350 ICE-VHCPTNELLTDS--TGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEK 2406
+CE + CP + + TG G P + S+ PD ++
Sbjct: 1768 VCEQIFCPNPPAILNGRHTGTPF-----GDIPYGKEISYACDTHPDRGMTFN-------- 1814
Query: 2407 QYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAP 2466
L G S N V WSS R + + P
Sbjct: 1815 --------------------LIGESSIRCTSDPQGNGV---WSSPAP--RCELSVPAACP 1849
Query: 2467 YCSLPRAPLHGFILGQTSTQPGG-SIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPL 2525
+ P+ +I G S G +I + C+ GY LVG CT QG +WS+
Sbjct: 1850 H--PPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCT--DQG--IWSQLDHY 1903
Query: 2526 CQALSCGLP---EAPKNGMVFGKEYTVGTKAMYSCSEGYHLQ 2564
C+ ++C P + K Y G C +GY L+
Sbjct: 1904 CKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLE 1945
Score = 95.1 bits (235), Expect = 1e-18
Identities = 225/1017 (22%), Positives = 342/1017 (33%), Gaps = 243/1017 (23%)
Query: 327 KTSVLTQVGVSQGHNMCPDPGIPERGK-RLGSDFRLGSSVQFTCNEGYDLQGSKRITCMK 385
K SV T C +P P G + + GS ++++C +GY L GS TC+
Sbjct: 88 KNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCI- 146
Query: 386 VSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIIT-ALNPSKVI 444
+S W + P+C C G IT+ +F N H ++T NP
Sbjct: 147 ISGDTVIWDNETPICDRIPC-----GLPPTITNGDFISTNRENFHYGSVVTYRCNP---- 197
Query: 445 KLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSG 504
G GG+ ++ L G P + ++N ++
Sbjct: 198 ------------------GSGGRK------VFELVGE--PSIYCTSNDDQVGIWSGPAPQ 231
Query: 505 SSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKN 564
+ K + +E GI R S F + ++F CQP F + G + + CQ
Sbjct: 232 CIIPNKCTPPNVEN------GILVSDNR--SLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 283
Query: 565 NQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDID 624
N+W + P C C P V+ + D N P + +
Sbjct: 284 NKWEPELPSCSRVC----QPPPDVLHAERTQRDKDNF---------SPGQEVFYS----- 325
Query: 625 VEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFT 684
EP +D A + T G+ P++
Sbjct: 326 CEPGYDL-------RGAASMRCTPQGDWSPAA---------------------------P 351
Query: 685 TFRHNECPD-PGVPVNGK-RFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWN 742
T C D G +NG+ F +LQLG+ + F+CDEGF +GS CVL +WN
Sbjct: 352 TCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGF-QLKGSSASYCVLAGMESLWN 410
Query: 743 SAVLRCEAPCGGHLTSPSGTILSPG-WPGFYKDALSCAWVIE--AQPGYPIKITFDRFKT 799
S+V CE + PS ++ G G + + P +FD
Sbjct: 411 SSVPVCE-----QIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGE 465
Query: 800 EVNYDTLEVRDGRTYS--APLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRY 857
T + + +S AP G+ Q P + + L T+ S IG L+Y
Sbjct: 466 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFL----FAKLKTQTNASDFPIGTSLKY 521
Query: 858 E----------TIT-------------LQSDHCLDPGIPVNGQRHG-NDFYVGALVTFSC 893
E +IT + C P PVNG H D VG+ + +SC
Sbjct: 522 ECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSC 581
Query: 894 DSGYTLSDGEPLECEPN---FQWSRALPSCEAL-CGGFIQGSSGTILSPGFPDFYPNNLN 949
+G+ L EC + WS P C+ + CG ++G +S +F+ ++
Sbjct: 582 TTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVV 641
Query: 950 CTWIIETSHGKGVFFTFHTFHLESGHDYLLITEN----GSFTQPLRQ--LTGSRLPAPIS 1003
S G+ VF G + T N G ++ P Q + P +
Sbjct: 642 TYRCNPGSGGRKVFELV-------GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVE 694
Query: 1004 AGLYGN-------------FTAQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSI- 1049
G+ + F Q F+ + + E +L C P +
Sbjct: 695 NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVL 754
Query: 1050 ------RKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVT 1103
R F G + +SC PGY L G A + C + WS P C + S
Sbjct: 755 HAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT--PQGDWSPAAPTCEVK---SCD 809
Query: 1104 GTQGTLLSPN--FPVNYNNNHECIYSIQTQPGKGIQLKARA-FELSEGDVLKVYDGNNNS 1160
G LL+ FPVN +QL A+ F EG LK +S
Sbjct: 810 DFMGQLLNGRVLFPVN------------------LQLGAKVDFVCDEGFQLK-----GSS 846
Query: 1161 ARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCEDPGTPKFG 1220
A S+ + G+ SLW + E I C P G
Sbjct: 847 A------SYCVLAGM------ESLWNSSVPVCEQ--------------IFCPSPPVIPNG 880
Query: 1221 YKVHD--EGHFAGSSVSFSCDP------GYSLRGSEELLCLSGER--RTWDRPLPTC 1267
E G +V+++CDP + L G + C S + W P P C
Sbjct: 881 RHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 937
Score = 84.3 bits (207), Expect = 2e-15
Identities = 231/1082 (21%), Positives = 363/1082 (33%), Gaps = 244/1082 (22%)
Query: 343 CPDPGIPERGK-RLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCR 401
C P P G + +D ++GS + ++C G+ L G C+ +S A WS P+C+
Sbjct: 1004 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECI-LSGNTAHWSTKPPICQ 1062
Query: 402 ARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLT 461
C G I + +F N H ++T
Sbjct: 1063 RIPC-----GLPPTIANGDFISTNRENFHYGSVVTY---------------------RCN 1096
Query: 462 VGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSC 521
+G G+ ++ L G P + ++N ++ + K + +E G
Sbjct: 1097 LGSRGRK------VFELVGE--PSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENG-- 1146
Query: 522 GDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFN 581
I R S F + ++F CQP F + G + + CQ N+W + P C C
Sbjct: 1147 ----ILVSDNR--SLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC--- 1197
Query: 582 FTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHL-AFNDIDVEPQFDFLVIKDGATA 640
P +L + + ++ + E L + PQ D+ +
Sbjct: 1198 --QPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDW-------SP 1248
Query: 641 EAPVLGTFSGNQLPSSITSSGHV---------ARLEFQTDHSTGKRGFNITFTTF----- 686
EAP S + + G V A++ F D +G +++
Sbjct: 1249 EAPRCAVKSCDDFLGQLPH-GRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRS 1307
Query: 687 ---------RHNECPDPGVPVNGKRFG---DSLQLGSSISFLCDEG-----FLGTQGSET 729
H CP+P +NG+ G + G IS+ CD G T
Sbjct: 1308 LWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGEST 1367
Query: 730 ITCVL-KEGSVVWNSAVLRCEAPC-GGHLTSPSG-TILSPGWP-GFYKDALSCAWVIEAQ 785
I C G+ VW+S RCE GH +P SP P ++ + + E +
Sbjct: 1368 IRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECR 1427
Query: 786 PGYPIKITFDRFKTEVNYDTLEVRDGRTYSA----PLIGVYHGTQVPQFLISTSNY---- 837
PGY K+ + + ++E R P G+ H QF ST NY
Sbjct: 1428 PGYFGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQF-GSTVNYSCNE 1486
Query: 838 -LYLLFSTDKSHSDIGFQLRYE--TITLQSDHCLDPGIPVNGQRHGND---FYVGALVTF 891
L+ S + G + ++ + C P NG + N+ F+ G +VT+
Sbjct: 1487 GFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTY 1546
Query: 892 SCDSGYTLSDGEPL-------------ECEPNFQWSRALPSCEALCGGFIQGSSGTILSP 938
C +G DGE L + + WS P C + I P
Sbjct: 1547 QCHTG---PDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVP 1603
Query: 939 GFPDFYPNNLNCTWIIETSHGKG-VFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSR 997
G F+ T II G V HT ++ NG + L SR
Sbjct: 1604 GNRSFF----TLTEIIRFRCQPGFVMVGSHTVQCQT---------NGRWGPKLPHC--SR 1648
Query: 998 LPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCE----------EPEVPAY 1047
+ P L+G T + +FS E F YDL PE P
Sbjct: 1649 VCQPPPEILHGEHTLSHQ--DNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC 1706
Query: 1048 SIRK---------------GLQFGVGDTLTFSCFPGYRLEGTARITC-LGGRRRLWSSPL 1091
+++ L +G ++F C G+RL+G + C L G + LW+S +
Sbjct: 1707 TVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSV 1766
Query: 1092 PRCVAECGNSVTGTQGTLLSPNFPVNYNNNH------------ECIYSIQTQPGKGIQLK 1139
P C + PN P N H E Y+ T P +G+
Sbjct: 1767 PVC------------EQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFN 1814
Query: 1140 ARAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSS----------------- 1182
+ E + D N GV+S S L+ ++
Sbjct: 1815 L----IGESSIRCTSDPQGN-----GVWS-SPAPRCELSVPAACPHPPKIQNGHYIGGHV 1864
Query: 1183 SLWLDFITDAENTSKGFELHFSSFELIKCEDPGT---------------PKFGYKVHDE- 1226
SL+L +T + G+ L F I C D G P F + E
Sbjct: 1865 SLYLPGMTISYICDPGYLLVGKGF--IFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKEL 1922
Query: 1227 ----GHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAEC-GGTVRGEVSG 1281
+ G V+ C+ GY+L GS C + +R WD PL C + + G +SG
Sbjct: 1923 EMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDR--WDPPLAKCTSRTHDALIVGTLSG 1980
Query: 1282 QV 1283
+
Sbjct: 1981 TI 1982
Score = 80.1 bits (196), Expect = 4e-14
Identities = 237/1065 (22%), Positives = 366/1065 (34%), Gaps = 214/1065 (20%)
Query: 344 PDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRAR 403
PD ER +R +F G V ++C GYDL+G+ + C D WS P C +
Sbjct: 301 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGD----WSPAAPTCEVK 356
Query: 404 MCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVG 463
CD +F Q N L P + A +F + G+
Sbjct: 357 SCD-------------DFMGQLLNG-------RVLFPVNLQLGAKVDFVCDEGFQ----- 391
Query: 464 DGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGD 523
L G+S +++ +W +S EQ C
Sbjct: 392 --------------LKGSSASYCVLAGMESLW--------------NSSVPVCEQIFCPS 423
Query: 524 PGIPAYGRREGSR---FHHGDTLKFECQP------AFELVGQKAITC----QKNNQWSAK 570
P + GR G F G T+ + C P +F+L+G+ I C Q N WS+
Sbjct: 424 PPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSP 483
Query: 571 KPGC--VFSC----FFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDID 624
P C + C F F + ++P C RP S I N +
Sbjct: 484 APRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFS-ITCLDNLVW 542
Query: 625 VEPQFDFLVIKDGATAEAPVLG---TFSGNQLPSSIT---SSGH--VARLEFQTDHSTGK 676
P+ D K T PV G + Q+ S I ++GH + + S
Sbjct: 543 SSPK-DVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNA 601
Query: 677 RGFNITFTTFRHNECPDPGVPVNGKRFG---DSLQLGSSISFLCDEGFLGTQ-----GSE 728
++ + C P NG ++ GS +++ C+ G G + G
Sbjct: 602 AHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEP 661
Query: 729 TITCVLKEGSV-VWNSAVLRCEAPCGGHLTSP---SGTILSPGWPGFYKDALSCAWVIE- 783
+I C + V +W+ +C P T P +G ++S + S V+E
Sbjct: 662 SIYCTSNDDQVGIWSGPAPQCIIP--NKCTPPNVENGILVSDN-----RSLFSLNEVVEF 714
Query: 784 -AQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLF 842
QPG+ +K +N E+ P V H + + + S + +
Sbjct: 715 RCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFY 774
Query: 843 STDKSHSDIGFQLRYET---ITLQSDHCLDPGIPVNGQRHGNDF---------------Y 884
S + G+ LR T Q D P P + +DF
Sbjct: 775 SCEP-----GYDLRGAASMRCTPQGD--WSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQ 827
Query: 885 VGALVTFSCDSGYTLSDGEPLEC---EPNFQWSRALPSCEALCGGFIQGSSGTILSPGFP 941
+GA V F CD G+ L C W+ ++P CE I P P
Sbjct: 828 LGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE------------QIFCPS-P 874
Query: 942 DFYPNNLNCTWIIET-SHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGS-RLP 999
PN + +E GK V +T H + G + LI E+ Q G P
Sbjct: 875 PVIPNGRHTGKPLEVFPFGKAVNYTCDP-HPDRGTSFDLIGESTIRCTSDPQGNGVWSSP 933
Query: 1000 APISAGLYGNFTAQVRFI----------SDF----SMSYE--------GFNIT------- 1030
AP G+ G+ A F+ SDF S+ YE F+IT
Sbjct: 934 AP-RCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVW 992
Query: 1031 FSEYDL---EPCEEPEVPAYS-IRKGLQFGVGDTLTFSCFPGYRLEGTARITC-LGGRRR 1085
S D+ + C+ P P + VG + +SC G+RL G + C L G
Sbjct: 993 SSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTA 1052
Query: 1086 LWSSPLPRCV-AECGNSVTGTQGTLLSPNFPVNYNNNHECIY--SIQTQPGKGIQL--KA 1140
WS+ P C CG T G +S N N++ Y ++ ++ K +L +
Sbjct: 1053 HWSTKPPICQRIPCGLPPTIANGDFISTN-RENFHYGSVVTYRCNLGSRGRKVFELVGEP 1111
Query: 1141 RAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLW-----LDFITDAENT 1195
+ S D + ++ G + + + L S + SL+ ++F
Sbjct: 1112 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV 1171
Query: 1196 SKG-----------FELHFSSFELIKCEDPGTPKFGYKV--HDEGHFAGSSVSFSCDPGY 1242
KG +E S + C+ P G H + G V +SC+PGY
Sbjct: 1172 MKGPRRVKCQALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGY 1230
Query: 1243 SLRGSEELLCLSGERRTWDRPLPTCVAECGGTVRGEV-SGQVLSP 1286
LRG+ L C + W P C + G++ G+VL P
Sbjct: 1231 DLRGAASLHCT--PQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFP 1273
Score = 48.9 bits (115), Expect = 9e-05
Identities = 104/483 (21%), Positives = 171/483 (35%), Gaps = 85/483 (17%)
Query: 142 PGRLPNGI---QQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRA 198
P + NGI S F+L + V + C GF ++G + C A ++ W+ LPS
Sbjct: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPS--- 1192
Query: 199 DDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEV 258
C + I+ H PS N + G + + E GYD
Sbjct: 1193 ---CSRVCQPPPEILHGEHTPSHQDNFSP---------GQEVF-----YSCEPGYDLRGA 1235
Query: 259 TGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIE-LKSRGVK 317
+ P + S + F H + F Q+ ++ + G +
Sbjct: 1236 ASLHCTPQGDWSPEAPRCAVKSCD----DFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFR 1291
Query: 318 LMPSKDNSQKTSVL--------TQVGVSQGHNMCPDPGIPERGKRLGS---DFRLGSSVQ 366
L K +S VL V V + H CP+P G+ G+ D G +
Sbjct: 1292 L---KGSSVSHCVLVGMRSLWNNSVPVCE-HIFCPNPPAILNGRHTGTPSGDIPYGKEIS 1347
Query: 367 FTCNE------GYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGI-ITSP 419
+TC+ ++L G I C WS P C + H + P SP
Sbjct: 1348 YTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASP 1407
Query: 420 NFPIQYDNNAHCVWIITALN----PSKVIKL----AFEEFDLERGYDTLTVGDGGQDGDQ 471
PI N + T+LN P K+ E D G +
Sbjct: 1408 TIPI----NDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCGPPPEP 1463
Query: 472 -KTVLYILTGTSVPDLIVSTNHQMWLLFQTDG-----SGSSLGFKASYEEIEQGSCGDPG 525
+++I T T + + ++ + L + SG+++ + E SC P
Sbjct: 1464 FNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPP 1523
Query: 526 IPAYG---RREGSRFHHGDTLKFEC------QPAFELVGQKAITC-QKNNQ---WSAKKP 572
+ G + FH+G + ++C + FELVG+++I C K++Q WS+ P
Sbjct: 1524 TISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPP 1583
Query: 573 GCV 575
C+
Sbjct: 1584 RCI 1586
Score = 47.0 bits (110), Expect = 3e-04
Identities = 111/530 (20%), Positives = 180/530 (33%), Gaps = 107/530 (20%)
Query: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSA--QGFHATYE----VLPSHTC 139
PP+P N + + V+ + RLI + + G + T++ + +C
Sbjct: 1460 PPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISC 1519
Query: 140 GNPGRLPNG---IQQGSTFNLGDKVRYSCNLG------FFLEGHAVLTCHAGSENSATWD 190
P + NG ++F+ G V Y C+ G F L G + C + + W
Sbjct: 1520 EPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWS 1579
Query: 191 FPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLE 250
P P C + + C ++P + + ++ L E+ I F+ +
Sbjct: 1580 SPPPRCISTNKC-----------TAPEVENAIRVPGNRSFFTLTEI--------IRFRCQ 1620
Query: 251 DGYDFL-------EVTGTEGSSL-WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQ 302
G+ + + G G L + P P I H S ++ G
Sbjct: 1621 PGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGE----HTLSHQDNFSPGQEVF 1676
Query: 303 YQVKKQIELK-SRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPD--PGIPERGKRLGSDF 359
Y + +L+ + + P D S + T C D +P L +
Sbjct: 1677 YSCEPSYDLRGAASLHCTPQGDWSPEAPRCTV-------KSCDDFLGQLPHGRVLLPLNL 1729
Query: 360 RLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSP 419
+LG+ V F C+EG+ L+G C+ ++ M A W+ PVC C P
Sbjct: 1730 QLGAKVSFVCDEGFRLKGRSASHCV-LAGMKALWNSSVPVCEQIFC-------------P 1775
Query: 420 NFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILT 479
N P N H + K I A + +RG +G+ +
Sbjct: 1776 N-PPAILNGRHTGTPFGDIPYGKEISYACDTHP-DRGMTFNLIGESS-----------IR 1822
Query: 480 GTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREG---SR 536
TS P Q +G SS + E +C P G G S
Sbjct: 1823 CTSDP--------------QGNGVWSSPAPRC--ELSVPAACPHPPKIQNGHYIGGHVSL 1866
Query: 537 FHHGDTLKFECQPAFELVGQKAITCQKNNQWS-----AKKPGCVFSCFFN 581
+ G T+ + C P + LVG+ I C WS K+ C F F N
Sbjct: 1867 YLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMN 1916
Score = 45.1 bits (105), Expect = 0.001
Identities = 154/721 (21%), Positives = 238/721 (33%), Gaps = 172/721 (23%)
Query: 305 VKKQIELKSRGVKL--MPSKDNSQKTSVLTQVGVSQGH-------NMCPDPGIPERGKRL 355
V + L SRG K+ + + + TS QVG+ G N C P + E G +
Sbjct: 1091 VTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV-ENGILV 1149
Query: 356 GSD---FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGP 412
+ F L V+F C G+ ++G +R+ C ++ W P C +R+C + P
Sbjct: 1150 SDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALN----KWEPELPSC-SRVC----QPP 1200
Query: 413 SGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTL---TVGDGGQDG 469
I+ + P DN + + + P +DL RG +L GD +
Sbjct: 1201 PEILHGEHTPSHQDNFSPGQEVFYSCEPG---------YDL-RGAASLHCTPQGDWSPEA 1250
Query: 470 DQKTVLYILTGTSVPDLIVSTNHQMWLL-----------------FQTDGSGSS----LG 508
+ V S D + H L F+ GS S +G
Sbjct: 1251 PRCAV------KSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVG 1304
Query: 509 FKA----SYEEIEQGSCGDPGIPAYGRREGS---RFHHGDTLKFECQP------AFELVG 555
++ S E C +P GR G+ +G + + C P F L+G
Sbjct: 1305 MRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIG 1364
Query: 556 QKAITCQK----NNQWSAKKPGCVFSC---------FFNFTSPSGVVLSPNYPEDYGNHL 602
+ I C N WS+ P C S F F SP+ + +P +
Sbjct: 1365 ESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNY 1424
Query: 603 HCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEA--PVLGTFSG-------NQL 653
C RP F+ I + ++D ++ P F+G Q
Sbjct: 1425 EC------RP-GYFGKMFS-ISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQF 1476
Query: 654 PSSIT-SSGHVARLEFQTDHSTGKRGFNITF----TTFRHNECPDPGVPVNGKRFGD--- 705
S++ S RL + G N+T+ C P NG + +
Sbjct: 1477 GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRT 1536
Query: 706 SLQLGSSISFLCDEGFLGTQ-----GSETITCVLKEGSV-VWNSAVLRCEAPCGGHLTSP 759
S G+ +++ C G G Q G +I C K+ V VW+S RC +
Sbjct: 1537 SFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEV 1596
Query: 760 SGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLI 819
I PG F+ L+ QPG+ + V T++ + + L
Sbjct: 1597 ENAIRVPGNRSFF--TLTEIIRFRCQPGFVM----------VGSHTVQCQTNGRWGPKLP 1644
Query: 820 GVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRH 879
Q P ++ + L SH D
Sbjct: 1645 HCSRVCQPPPEILHGEHTL--------SHQD----------------------------- 1667
Query: 880 GNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEA-LCGGFI-QGSSGTILS 937
+F G V +SC+ Y L L C P WS P C C F+ Q G +L
Sbjct: 1668 --NFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLL 1725
Query: 938 P 938
P
Sbjct: 1726 P 1726
Score = 40.4 bits (93), Expect = 0.031
Identities = 25/60 (41%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
Query: 138 TCGNPGRLPNGIQQGST-FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
+CG P NG+ +T G V YSCN GF L G TC S N+ TWD P C
Sbjct: 1456 SCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLV-SGNNVTWDKKAPIC 1514
Score = 38.1 bits (87), Expect = 0.15
Identities = 37/133 (27%), Positives = 49/133 (36%), Gaps = 17/133 (12%)
Query: 86 PPQPENLRTR-LTGFQLPATIVSAATTLSLRLISDYAVSA--QGFHATYEVLPSHT---- 138
PP P N +T Q+ + I + TT RLI + G A + P
Sbjct: 1007 PPDPVNGMVHVITDIQVGSRINYSCTT-GHRLIGHSSAECILSGNTAHWSTKPPICQRIP 1065
Query: 139 CGNPGRLPNG---IQQGSTFNLGDKVRYSCNLG------FFLEGHAVLTCHAGSENSATW 189
CG P + NG F+ G V Y CNLG F L G + C + + W
Sbjct: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
Query: 190 DFPLPSCRADDAC 202
P P C + C
Sbjct: 1126 SGPAPQCIIPNKC 1138
Score = 36.2 bits (82), Expect = 0.58
Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 9/67 (13%)
Query: 139 CGNPGRLPNGIQQGS---TFNLGDKVRYSCN------LGFFLEGHAVLTCHAGSENSATW 189
C +P +PNG G F G V Y+C+ F L G + + C + + + W
Sbjct: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
Query: 190 DFPLPSC 196
P P C
Sbjct: 481 SSPAPRC 487
Score = 36.2 bits (82), Expect = 0.58
Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 9/67 (13%)
Query: 139 CGNPGRLPNGIQQGS---TFNLGDKVRYSCN------LGFFLEGHAVLTCHAGSENSATW 189
C +P +PNG G F G V Y+C+ F L G + + C + + + W
Sbjct: 871 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 930
Query: 190 DFPLPSC 196
P P C
Sbjct: 931 SSPAPRC 937
Score = 35.8 bits (81), Expect = 0.76
Identities = 29/131 (22%), Positives = 49/131 (37%), Gaps = 18/131 (13%)
Query: 98 GFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRLPNGIQQGSTFN- 156
GF+L + VS + +R + + +V V C NP + NG G+
Sbjct: 1289 GFRLKGSSVSHCVLVGMRSLWNNSVP---------VCEHIFCPNPPAILNGRHTGTPSGD 1339
Query: 157 --LGDKVRYSCN------LGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRG 208
G ++ Y+C+ + F L G + + C + + W P P C G
Sbjct: 1340 IPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTP 1399
Query: 209 QSGIISSPHFP 219
+ +SP P
Sbjct: 1400 EQFPFASPTIP 1410
Score = 33.9 bits (76), Expect = 2.9
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 2/67 (2%)
Query: 132 EVLPSHTCGNPGRLPNGIQQGST-FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWD 190
+V +C P NG+ T +G ++ YSC G L GH+ C S N+A W
Sbjct: 547 DVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNAAHWS 605
Query: 191 FPLPSCR 197
P C+
Sbjct: 606 TKPPICQ 612
Score = 33.9 bits (76), Expect = 2.9
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 2/67 (2%)
Query: 132 EVLPSHTCGNPGRLPNGIQQGST-FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWD 190
+V +C P NG+ T +G ++ YSC G L GH+ C S N+A W
Sbjct: 997 DVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNTAHWS 1055
Query: 191 FPLPSCR 197
P C+
Sbjct: 1056 TKPPICQ 1062
Score = 33.9 bits (76), Expect = 2.9
Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 5/59 (8%)
Query: 883 FYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSC-----EALCGGFIQGSSGTIL 936
++ G VT C+ GYTL +C+ + +W L C +AL G + G+ IL
Sbjct: 1928 YHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTSRTHDALIVGTLSGTIFFIL 1986
Score = 33.1 bits (74), Expect = 5.0
Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 138 TCGNPGRLPNG---IQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLP 194
+C NP NG + +G F G +++YSC G+ L G + TC S ++ WD P
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQF--GSQIKYSCTKGYRLIGSSSATCII-SGDTVIWDNETP 159
Query: 195 SC 196
C
Sbjct: 160 IC 161
Score = 32.7 bits (73), Expect = 6.5
Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 7/58 (12%)
Query: 142 PGRLPNGI---QQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
P + NGI S F+L + V + C GF ++G + C A ++ W+ LPSC
Sbjct: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPSC 293
Score = 32.7 bits (73), Expect = 6.5
Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 7/58 (12%)
Query: 142 PGRLPNGI---QQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
P + NGI S F+L + V + C GF ++G + C A ++ W+ LPSC
Sbjct: 690 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPSC 743
>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
isoform 1 [Homo sapiens]
Length = 1092
Score = 278 bits (711), Expect = 7e-74
Identities = 264/1033 (25%), Positives = 415/1033 (40%), Gaps = 114/1033 (11%)
Query: 2296 PPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQ--FEGPPPICEV 2353
PP IL N + + +G ++RY C F L+G + L C + ++ P P CE
Sbjct: 26 PPPIL-NGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEY 84
Query: 2354 HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEI 2413
N+ + ++ PG Y + + + ++ + +
Sbjct: 85 F---NKYSSCPEPIV-----PGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANN 136
Query: 2414 FDGPSG----------QSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKI-- 2461
GP+ + P L + + V S + + + +S + Y G KI
Sbjct: 137 MWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIIN 196
Query: 2462 -----RYSA--PYCSLPRAPLHG-FILGQTSTQP----GGSIHFGCNAGYRLVGHSMAIC 2509
++SA P C R G F G+ P G + +F C+ GYRL G + C
Sbjct: 197 CLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRC 256
Query: 2510 TRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGKEY---TVGTKAMYSCS----EGYH 2562
QG W++ +P+C+ + C P NG G + G+ Y+C EG +
Sbjct: 257 VIAGQGV-AWTK-MPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
Query: 2563 LQAGAEATAECL----DTGLWSNRNVPPQCV----PVTCPDVSSISVEHGRWRLIFETQY 2614
E+T C TG WS P+C V CP + GR + +Y
Sbjct: 315 FILIGESTLRCTVDSQKTGTWSGP--APRCELSTSAVQCPHPQIL---RGRMVSGQKDRY 369
Query: 2615 QFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLS 2674
+ ++ C G+ G + IRC A G W S P C C P NG +
Sbjct: 370 TYNDTVIFACMFGFTLKGSKQIRCNAQGTWE--PSAPVCEK-ECQAPPNILNGQKEDRHM 426
Query: 2675 VY---GATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHC-GTPEPIVNGHINGE 2730
V G + +SCN GY LVG +C + G+W+ +C C T ++ +
Sbjct: 427 VRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLT---KPQ 483
Query: 2731 NYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPG---SPPHSQMSG 2787
+ R V C G++L G + CQ W + C ++C P + H+ S
Sbjct: 484 HQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSL 543
Query: 2788 DSYTVGAVVRYSCIG------KRTLVGNSTRMCGLD----GHWTGSLPHCSGTSVGV-CG 2836
+ + G V Y+C + +L+G ST C + G W+G P C + + V C
Sbjct: 544 EDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCS 603
Query: 2837 DPGIPAHGIRLGDSFDP---GTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISC 2893
I A+G ++ P + F C +G L+GSS+ C+A+ +W P C C
Sbjct: 604 HVHI-ANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEK-GC 661
Query: 2894 GNPGTPSNARVVFSDGLVFSSSIV--YECREGYYATGLLSRHCSVNGTWTGSDPECLVIN 2951
+P + R + + F S + Y C GY G S HC +G W+ S P C
Sbjct: 662 QSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEE-T 720
Query: 2952 CGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALM 3011
C L G+ + V C GY + H + ++ W P+CK +
Sbjct: 721 CQHVRQSLQELPAGSRV---ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIH 777
Query: 3012 CKPPPLIPNGKVVG---SDFMWGSSVTYACLEGYQLSLPAVFTC----EGNGSWTGELPQ 3064
C PPP+I NGK G +F++G+ V+Y C +G+ L C +G+GSW+G PQ
Sbjct: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
Query: 3065 CF---PVF-CGDPGVPS--RGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSG 3118
C PV C +P V + + +S+ V C+P ++ GS C +D TW
Sbjct: 838 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVP 897
Query: 3119 TQPSCIDPTLTTCADPGVPQFGIQNNSQG----YQVGSTVLFRCQKGYLLQGSTTRTCLP 3174
P+CI C P P+ N++ G + G ++L+ C +GYLL G C
Sbjct: 898 GVPTCIKKAFIGCPPP--PKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTH 955
Query: 3175 NLTWSGTPPDCVPHHCRQPETPTHANVG--ALDLPSMGYTLIYSCQEGFSLKGGSEHRTC 3232
TWS P C +C P G + G + C++G+ L+ GS C
Sbjct: 956 EGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLE-GSPQSQC 1014
Query: 3233 KADGSWTGKPPIC 3245
++D W +C
Sbjct: 1015 QSDHQWNPPLAVC 1027
Score = 272 bits (695), Expect = 5e-72
Identities = 239/856 (27%), Positives = 333/856 (38%), Gaps = 102/856 (11%)
Query: 2468 CSLPRAPLHGFI-LGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLC 2526
C P L+G I T G I + C+ +RL+G +C + W + P C
Sbjct: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
Query: 2527 QAL----SCGLPEAPKNGMVFGKE-YTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSN 2581
+ SC P P + G Y G ++C + + C +W
Sbjct: 83 EYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVW--CQANNMWGP 140
Query: 2582 RNVPPQCV---PVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRC 2638
+P CV P+ CP + I H + C+ GY G+++I C
Sbjct: 141 TRLPT-CVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYS--CESGYLLVGEKIINC 197
Query: 2639 QANGKWSLGDSTPTCRIISCGELPIPPNGH-RIGTLSVYGATAIFSCNSGYTLVGSRVRE 2697
++GKWS PTC C L PNG + + G TA F C+ GY L G
Sbjct: 198 LSSGKWSA--VPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 2698 CMANG---LWSGSEVRCLAGHCGTPEPIVNG-HINGE--NYSYRGSVVYQCN------AG 2745
C+ G W+ V C C +P PI+NG HI N SY V Y C+
Sbjct: 256 CVIAGQGVAWTKMPV-CEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
Query: 2746 FRLIGMSVRICQQDHH----WSGKTPFCVL----VSCGHPGSPPHSQMSG--DSYTVGAV 2795
F LIG S C D WSG P C L V C HP +SG D YT
Sbjct: 315 FILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDT 374
Query: 2796 VRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSG---TSVGVCGDPGIPAHGIRLGDSFD 2852
V ++C+ TL G+ C G W S P C + H +R FD
Sbjct: 375 VIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVR----FD 430
Query: 2853 PGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPG----TPSNARVVFSD 2908
PGT +++SC G+VL G C + G W+ P+C V +C G T + V D
Sbjct: 431 PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPD 490
Query: 2909 GLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGN-- 2966
+ C EGY +G + + C W C I C P + NG G+
Sbjct: 491 -------VNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSL 543
Query: 2967 -DFRYNKTVTYQCVP----GYMMESHRVSVLSCTKD----RTWNGTKPVCK----ALMCK 3013
DF Y TVTY C P G S + CT + TW+G P+CK A+ C
Sbjct: 544 EDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCS 603
Query: 3014 PPPLIPNGKVVGSD--FMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCG 3071
+ K+ G + + + +VT+ C G+ L + C+ + +W E+P C
Sbjct: 604 HVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQS 663
Query: 3072 DPGVPSRGRREDRG---FSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTL 3128
PG+ GR F +V ++C P +LVG+ C G WS + P C +
Sbjct: 664 PPGL-HHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEE--- 719
Query: 3129 TTCADPGVPQFGIQNNSQGYQVGSTVLF---RCQKGYLLQGSTTRTC--LPNLTWSGTPP 3183
TC ++ + Q GS V CQ GY L G + C N W P
Sbjct: 720 -TCQH-------VRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIP 771
Query: 3184 DCVPHHCRQPETPTHANVGALDLPSM--GYTLIYSCQEGFSLKGGSEHRTCKAD----GS 3237
C HC P + + + G + Y C +GF L G + C++D GS
Sbjct: 772 LCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLL-GEKKLQCRSDSKGHGS 830
Query: 3238 WTGKPPICLEVRPSGR 3253
W+G P CL P R
Sbjct: 831 WSGPSPQCLRSPPVTR 846
Score = 238 bits (608), Expect = 6e-62
Identities = 219/834 (26%), Positives = 328/834 (39%), Gaps = 99/834 (11%)
Query: 2484 STQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVF 2543
S PG S+ + C +GY LVG + C + WS P C+ C NG V
Sbjct: 172 SIAPGLSVTYSCESGYLLVGEKIINCLSSGK----WSAVPPTCEEARCKSLGRFPNGKV- 226
Query: 2544 GKE---YTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSIS 2600
KE VG A + C EGY LQ ++ C+ G P C + CP S
Sbjct: 227 -KEPPILRVGVTANFFCDEGYRLQG--PPSSRCVIAGQGVAWTKMPVCEEIFCP--SPPP 281
Query: 2601 VEHGRWRLIFETQYQFQAQLMLICDP------GYYYTGQRVIRC----QANGKWSLGDST 2650
+ +GR + + + CDP + G+ +RC Q G WS
Sbjct: 282 ILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWS--GPA 339
Query: 2651 PTCRI-ISCGELPIPP--NGHRIGTLS---VYGATAIFSCNSGYTLVGSRVRECMANGLW 2704
P C + S + P P G + Y T IF+C G+TL GS+ C A G W
Sbjct: 340 PRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTW 399
Query: 2705 SGSEVRCLAGHCGTPEPIVNGHINGEN---YSYRGSVVYQCNAGFRLIGMSVRICQQDHH 2761
S C C P I+NG + + S+ Y CN G+ L+G C +
Sbjct: 400 EPSAPVC-EKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
Query: 2762 WSGKTPFCVLVSCGHPG-----SPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGL 2816
W+ P C + +C G P H + D V SC L G+ + C
Sbjct: 459 WTPPVPQCKVAACEATGRQLLTKPQHQFVRPD-------VNSSCGEGYKLSGSVYQECQG 511
Query: 2817 DGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDS---FDPGTVMRFSCEAG------HVL 2867
W + C + C P + +G G S F GT + ++C G L
Sbjct: 512 TIPWFMEIRLCKEIT---CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSL 568
Query: 2868 RGSSERTCQAN----GSWSGSQPECGV----ISCGNPGTPSNARVVFSDGLVF-SSSIVY 2918
G S C +N G+WSG P C + + C + + ++ + F + ++ +
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTF 628
Query: 2919 ECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGND--FRYNKTVTY 2976
+C G+ G C + TW P C PG+ GN F TV Y
Sbjct: 629 KCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDY 688
Query: 2977 QCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKAL---MCKPPPLIPNGKVVGSDFMWGSS 3033
C PGY++ ++ + C W+ + P C+ + + +P G V
Sbjct: 689 TCDPGYLLVGNKS--IHCMPSGNWSPSAPRCEETCQHVRQSLQELPAGSRV-------EL 739
Query: 3034 VTYACLEGYQLSLPAVFTCEG--NGSWTGELPQCFPVFCGDPGVPSRGRRED---RGFSY 3088
V +C +GYQL+ A C+ NG W ++P C + C P V G+ F Y
Sbjct: 740 VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLY 799
Query: 3089 RSSVSFSCHPPLVLVGSPRRFCQSD----GTWSGTQPSCI-DPTLTTCADPGVPQ-FGIQ 3142
+ VS+ C L+G + C+SD G+WSG P C+ P +T C +P V + +
Sbjct: 800 GNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLN 859
Query: 3143 NNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHC----RQPETPTH 3198
Y V C G+++ GS C + TW P C+ P+TP
Sbjct: 860 KTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNG 919
Query: 3199 ANVGA-LDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPS 3251
+ G + S G +++YSC +G+ L G + C +G+W+ P C EV S
Sbjct: 920 NHTGGNIARFSPGMSILYSCDQGYLLVGEAL-LLCTHEGTWSQPAPHCKEVNCS 972
Score = 182 bits (463), Expect = 4e-45
Identities = 154/564 (27%), Positives = 224/564 (39%), Gaps = 60/564 (10%)
Query: 2491 IHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFG---KEY 2547
++ C GY+L G C QG W I LC+ ++C P NG G +++
Sbjct: 491 VNSSCGEGYKLSGSVYQEC----QGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDF 546
Query: 2548 TVGTKAMYSCS----EGYHLQAGAEATAECL----DTGLWSNRNVPPQC-VPVTCPDVSS 2598
GT Y+C+ G E+T C + G WS P C + + S
Sbjct: 547 PYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGP--APLCKLSLLAVQCSH 604
Query: 2599 ISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISC 2658
+ + +G E Y + + C G+ G IRC+A+ W P C C
Sbjct: 605 VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWD--PEIPVCEK-GC 661
Query: 2659 GELPIPPNGHRIGTLSVY---GATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGH 2715
P +G G +V+ G T ++C+ GY LVG++ CM +G WS S RC
Sbjct: 662 QSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRC-EET 720
Query: 2716 CGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHH--WSGKTPFCVLVS 2773
C + G V C G++L G + ++CQ + W K P C ++
Sbjct: 721 CQHVRQSLQELPAGSRVEL---VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIH 777
Query: 2774 CGHPGSPP------HSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLD----GHWTGS 2823
C HP PP H+ M +++ G V Y C L+G C D G W+G
Sbjct: 778 C-HP--PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGP 834
Query: 2824 LPHC-SGTSVGVCGDPGIPAHGIRLG---DSFDPGTVMRFSCEAGHVLRGSSERTCQANG 2879
P C V C +P + HG +L ++ ++ C G ++ GS C +
Sbjct: 835 SPQCLRSPPVTRCPNPEVK-HGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDN 893
Query: 2880 SWSGSQPEC---GVISCGNPGTPSNARVVFSDGLVFSS--SIVYECREGYYATGLLSRHC 2934
+W P C I C P N + FS SI+Y C +GY G C
Sbjct: 894 TWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLC 953
Query: 2935 SVNGTWTGSDPECLVINCGDP----GIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVS 2990
+ GTW+ P C +NC P GI GL ++Y VT +C GYM+E S
Sbjct: 954 THEGTWSQPAPHCKEVNCSSPADMDGI-QKGLEPRKMYQYGAVVTLECEDGYMLEGSPQS 1012
Query: 2991 VLSCTKDRTWNGTKPVCKALMCKP 3014
C D WN VC++ P
Sbjct: 1013 --QCQSDHQWNPPLAVCRSRSLAP 1034
Score = 100 bits (250), Expect = 2e-20
Identities = 241/1130 (21%), Positives = 381/1130 (33%), Gaps = 264/1130 (23%)
Query: 1722 FVYQAVPRTSATQCSSVPEPRYGK--RLGSDFSVGAIVRFECNSGYALQGSPEIECLPVP 1779
F+ P C S P G+ + +VG ++R+ C+ + L G + C+
Sbjct: 10 FLALVAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKD 69
Query: 1780 GALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVV 1839
W+ AP C Y N + + +VP G I+
Sbjct: 70 KVDGTWDKPAPKC----------------------EYFNKYSSCPEPIVPGGYKIR---- 103
Query: 1840 SFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHL 1899
S G T +FS ++ +N + + + + F L
Sbjct: 104 --------GSTPYRHGDSVTFACKTNFSMNGNKSVWCQANN---MWGPTRLPTCVSVFPL 152
Query: 1900 EYKTVGLSSCPEPAVPSNGVKTGERYLVNDV-----VSFQCEPGYALQGHAHISCMPGTV 1954
E CP + NG T E V + V++ CE GY L G I+C+
Sbjct: 153 E--------CPALPMIHNGHHTSEN--VGSIAPGLSVTYSCESGYLLVGEKIINCLSSG- 201
Query: 1955 RRWNYPPPLCI-AQC-------GGTVEEMEGVILSPGFPGNY----------PSNMDC-- 1994
+W+ PP C A+C G V+E IL G N+ P + C
Sbjct: 202 -KWSAVPPTCEEARCKSLGRFPNGKVKEPP--ILRVGVTANFFCDEGYRLQGPPSSRCVI 258
Query: 1995 -----SW-KIAL----------PVGFGAHI----------QFLNFSTEPNHD----YIEI 2024
+W K+ + P+ G HI + ++ +P+ + +I I
Sbjct: 259 AGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILI 318
Query: 2025 RNGPYET---SRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQ 2081
S+ G +SG P LSTS H Q G + Q Y++
Sbjct: 319 GESTLRCTVDSQKTGTWSGPA-PRCELSTSA-----VQCPHPQILRGRMVSGQKDRYTYN 372
Query: 2082 ---ISSFLRGFDLSELERTNSTPPVAASYVWDLD-PGCEAYELQECPDPEPFANG----- 2132
I + + GF L ++ A W+ P CE +EC P NG
Sbjct: 373 DTVIFACMFGFTLKGSKQIRCN----AQGTWEPSAPVCE----KECQAPPNILNGQKEDR 424
Query: 2133 -IVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPC--------- 2182
+VR ++ G S+ + C PGY L G + C + W P+P+C+V
Sbjct: 425 HMVR---FDPGTSIKYSCNPGYVLVGEESIQCT--SEGVWTPPVPQCKVAACEATGRQLL 479
Query: 2183 --------GGNITSSNGTVYSPGFPSPYSSSQDCV-WLITV-----------PIGHGVRL 2222
++ SS G Y S Y Q + W + + P+ +
Sbjct: 480 TKPQHQFVRPDVNSSCGEGYKLS-GSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAH 538
Query: 2223 NLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIF 2282
S L+ P G +T P P GV + + T++ +SN G
Sbjct: 539 TGSSLEDFPYGTTVTYTCNP---GPERGVEFSLIGESTIRCTSND-----QERGTWSGPA 590
Query: 2283 AIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYL 2342
+ + +C I ++ + + D V ++C GFTL G+ + CK
Sbjct: 591 PLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADN-- 648
Query: 2343 QFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVE-- 2400
++ P+CE C QS PG + T V + T +
Sbjct: 649 TWDPEIPVCEKGC---------------QSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPG 693
Query: 2401 YFLSEKQYDEFEIFDGPSGQ-SP--------------LLKALSGNYSAPLIVTSSSNSVY 2445
Y L + I PSG SP L+ L L+ TS +
Sbjct: 694 YLLVGNK----SIHCMPSGNWSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQ 749
Query: 2446 LRWSSDHAY-------NRKGFKIRYSAPYCSL-----PRAPLHGFILGQTSTQ--PGGSI 2491
L + HAY N FK P C + P ++G G + G +
Sbjct: 750 L---TGHAYQMCQDAENGIWFK---KIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEV 803
Query: 2492 HFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLC----QALSCGLPEAPKNGMVFGK-- 2545
+ C+ G+ L+G C +G+ WS P C C PE K+G K
Sbjct: 804 SYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEV-KHGYKLNKTH 862
Query: 2546 -EYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVP--PQCVP---VTCPDVSSI 2599
Y+ C+ G+ + C W VP P C+ + CP
Sbjct: 863 SAYSHNDIVYVDCNPGFIM--NGSRVIRCHTDNTW----VPGVPTCIKKAFIGCPPPP-- 914
Query: 2600 SVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCG 2659
+G ++ ++ CD GY G+ ++ C G WS P C+ ++C
Sbjct: 915 KTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWS--QPAPHCKEVNCS 972
Query: 2660 ELPIPPNGHRIG----TLSVYGATAIFSCNSGYTLVGSRVRECMANGLWS 2705
P +G + G + YGA C GY L GS +C ++ W+
Sbjct: 973 S-PADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWN 1021
Score = 93.6 bits (231), Expect = 3e-18
Identities = 76/275 (27%), Positives = 120/275 (43%), Gaps = 24/275 (8%)
Query: 3005 PVCKALMCKPPPLIPNGKV--VGSDFMWGSSVTYACLEGYQL----SLPAVFTCEGNGSW 3058
P + C PP I NG++ + G+ + Y+C ++L SL + + +G+W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 3059 TGELPQC--FPVF--CGDPGVPSRGR-REDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSD 3113
P+C F + C +P VP + R + + SV+F+C + G+ +CQ++
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 3114 GTWSGTQ-PSCIDPTLTTCADPGVPQFG----IQNNSQGYQVGSTVLFRCQKGYLLQGST 3168
W T+ P+C+ C P +P N G +V + C+ GYLL G
Sbjct: 136 NMWGPTRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEK 193
Query: 3169 TRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSE 3228
CL + WS PP C C+ + V + +G T + C EG+ L+G
Sbjct: 194 IINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPS 253
Query: 3229 HRTCKADG---SWTGKPPICLEV-RPSGRPINTAR 3259
R C G +WT K P+C E+ PS PI R
Sbjct: 254 SR-CVIAGQGVAWT-KMPVCEEIFCPSPPPILNGR 286
Score = 71.6 bits (174), Expect = 1e-11
Identities = 215/1037 (20%), Positives = 355/1037 (34%), Gaps = 211/1037 (20%)
Query: 867 CLDPGIPVNGQRHGNDFYV-GALVTFSCDSGYTLSDGEPLECEPNFQWSRA-LPSCEALC 924
C +P +P + G+ Y G VTF+C + ++++ + + C+ N W LP+C ++
Sbjct: 91 CPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVF 150
Query: 925 GGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENG 984
+ P P + + + + G V T+ ESG YLL+
Sbjct: 151 ---------PLECPALPMIHNGHHTSENVGSIAPGLSV-----TYSCESG--YLLV---- 190
Query: 985 SFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCEEPEV 1044
G ++ +S+G + E + + +EP +
Sbjct: 191 ----------GEKIINCLSSGKWSAVPPTCE---------EARCKSLGRFPNGKVKEPPI 231
Query: 1045 PAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITC-LGGRRRLWSSPLPRCVA------- 1096
VG T F C GYRL+G C + G+ W+ +P C
Sbjct: 232 ----------LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTK-MPVCEEIFCPSPP 280
Query: 1097 ------ECGNSVTGTQ-GTLLS------PNFPVNY----NNNHECIYSIQ-----TQPGK 1134
GNS+ G++++ P VN+ + C Q + P
Sbjct: 281 PILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAP 340
Query: 1135 GIQLKARAFELSEGDVLK--VYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDA 1192
+L A + +L+ + G + + M G TL + +A
Sbjct: 341 RCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQ-----IRCNA 395
Query: 1193 ENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFA----GSSVSFSCDPGYSLRGSE 1248
+ T +E E +C+ P G K ++ H G+S+ +SC+PGY L G E
Sbjct: 396 QGT---WEPSAPVCEK-ECQAPPNILNGQK--EDRHMVRFDPGTSIKYSCNPGYVLVGEE 449
Query: 1249 ELLCLSGERRTWDRPLPTC-VAECGGTVRGEVSG---QVLSPGYPAPYEHNLNCIWTIEA 1304
+ C S W P+P C VA C T R ++ Q + P + ++
Sbjct: 450 SIQCTS--EGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQ 507
Query: 1305 EAGCTIGLHFLVFDTEEV------------HDVLRIWDGPVESGVLLKELSGPALPKDLH 1352
E TI + +E+ H + D P + V GP +
Sbjct: 508 ECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFS 567
Query: 1353 STFNSVVLQFSTDFFTSK-QGFAIQFSVST-ATSCNDPGIPQNGSRSGDS--WEAGDSTV 1408
S + S D G A +S A C+ I SG + D+
Sbjct: 568 LIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVT 627
Query: 1409 FQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCG-------GDLTGPSGVILSPNY 1461
F+C G+ L+GS++I C K +N W P P C C G TG + V
Sbjct: 628 FKCYSGFTLKGSSQIRC-KADNT--WDPEIPVCEKGCQSPPGLHHGRHTGGNTVF----- 679
Query: 1462 PEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLP 1521
+ G D+ T P Y++ +I + G ++ + S
Sbjct: 680 ---FVSGMTVDY--TCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQELPAG 734
Query: 1522 GRIE----SSSNSLFLAFRSDASVSNAGFVIDYTENPRES---CFDPGSIKNGTRVG--- 1571
R+E S + L + +A I + + P C P I NG G
Sbjct: 735 SRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMA 794
Query: 1572 SDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQYVGSDGVVL 1631
+ G+ V+Y C G+ + G L C G W+ P P C + S V
Sbjct: 795 ENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC--------LRSPPVTR 846
Query: 1632 SPN------YPQNYTSGQIC---LYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHS 1682
PN Y N T + +V +++ G + V+ H ++
Sbjct: 847 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNG---------SRVIRCHTDNTWVP 897
Query: 1683 RLLSSL--------------SGSHTGESLPLATSNQVLIKFSAKG---------LAPARG 1719
+ + + +G+HTG ++ + ++ +G L G
Sbjct: 898 GVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEG 957
Query: 1720 FHFVYQAVPRTSATQCSSVPEPRYGKRLGSD----FSVGAIVRFECNSGYALQGSPEIEC 1775
Q P CSS P G + G + + GA+V EC GY L+GSP+ +C
Sbjct: 958 TWS--QPAPHCKEVNCSS-PADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC 1014
Query: 1776 LPVPGALAQWNVSAPTC 1792
+ QWN C
Sbjct: 1015 ----QSDHQWNPPLAVC 1027
Score = 70.1 bits (170), Expect = 4e-11
Identities = 166/840 (19%), Positives = 269/840 (32%), Gaps = 162/840 (19%)
Query: 1031 FSEYDLEPCEEPEVPA-YSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWS- 1088
F++Y C EP VP Y IR + GD++TF+C + + G + C +W
Sbjct: 85 FNKYS--SCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANN--MWGP 140
Query: 1089 SPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEG 1148
+ LP CV+ L P P+ +N +H PG + + L G
Sbjct: 141 TRLPTCVSVF---------PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVG 191
Query: 1149 DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFEL 1208
+ + +N SS W E
Sbjct: 192 EKI-------------------------INCLSSGKWSAVPPTCEEA------------- 213
Query: 1209 IKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLC-LSGERRTWDRPLPTC 1267
+C+ G G G + +F CD GY L+G C ++G+ W + +P C
Sbjct: 214 -RCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTK-MPVC 271
Query: 1268 VA-------------ECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHF 1314
G ++ G +++ E +N I E+ CT+
Sbjct: 272 EEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTV---- 327
Query: 1315 LVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHS----------TFNSVVLQFST 1364
D+++ W GP L P+ L T+N V+
Sbjct: 328 ---DSQKTGT----WSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACM 380
Query: 1365 DFFTSKQGFAIQFSVSTA---------TSCNDPGIPQNGSRSGDS---WEAGDSTVFQCD 1412
FT K I+ + C P NG + ++ G S + C+
Sbjct: 381 FGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCN 440
Query: 1413 PGYALQGSAEISCVKIENRFFWQPSPPTC-IAPCGGD----LTGPSGVILSPNYPEPYPP 1467
PGY L G I C + W P P C +A C LT P + P+
Sbjct: 441 PGYVLVGEESIQCT---SEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGE 497
Query: 1468 GKECDWKV------TVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQL- 1520
G + V T+ I L I P IY+G + S L YG+ +
Sbjct: 498 GYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPV----IYNGAHTGSSLEDFPYGTTVT 553
Query: 1521 ----PGRIESSSNSLF--LAFRSDASVSNAGFVIDYTENPRESC--------FDPGSIKN 1566
PG SL R ++ G P C I N
Sbjct: 554 YTCNPGPERGVEFSLIGESTIRCTSNDQERG----TWSGPAPLCKLSLLAVQCSHVHIAN 609
Query: 1567 GTRVG---SDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPC---- 1619
G ++ + +VT+ C+ G+ ++G+S + C W+ PVC C
Sbjct: 610 GYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC----KADNTWDPEIPVCEKGCQSPP 665
Query: 1620 ---GGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHD 1676
G++ G + V +YT L + G ++ + +
Sbjct: 666 GLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQ--- 722
Query: 1677 GHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCS 1736
H + S L L E + + + + A + ++ +P C
Sbjct: 723 -HVRQS--LQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCH 779
Query: 1737 SVPEPRYGKRLG---SDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCV 1793
P GK G +F G V +EC+ G+ L G +++C W+ +P C+
Sbjct: 780 PPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCL 839
Score = 60.1 bits (144), Expect = 4e-08
Identities = 106/461 (22%), Positives = 160/461 (34%), Gaps = 83/461 (18%)
Query: 837 YLYLLFSTDKSHSDIGFQLRYET-ITLQSDHCLDPGIPV--------NGQRHGND----- 882
Y Y T K +S GF L+ + I ++D+ DP IPV G HG
Sbjct: 620 YFYNDTVTFKCYS--GFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNT 677
Query: 883 --FYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGGFIQ-------GSSG 933
F G V ++CD GY L + + C P+ WS + P CE C Q GS
Sbjct: 678 VFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQELPAGSRV 737
Query: 934 TILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQ- 992
+++ D Y + + + + F + H +I NG T + +
Sbjct: 738 ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIV-NGKHTGMMAEN 796
Query: 993 -LTGSRLPAPISAGLY--GNFTAQVRFISDFSMSYEGFN-ITFSEYDLEPCEEPEVP-AY 1047
L G+ + G Y G Q R S S+ G + + C PEV Y
Sbjct: 797 FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGY 856
Query: 1048 SIRK-GLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQ 1106
+ K + D + C PG+ + G+ I C W +P C+ +
Sbjct: 857 KLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRC--HTDNTWVPGVPTCI---------KK 905
Query: 1107 GTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGV 1166
+ P P N NH + PG I L G+ L + G
Sbjct: 906 AFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHE-------GT 958
Query: 1167 FSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDE 1226
+S +N +S + D + KG E P+ Y+
Sbjct: 959 WSQPAPHCKEVNCSSPA-------DMDGIQKGLE----------------PRKMYQY--- 992
Query: 1227 GHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTC 1267
G+ V+ C+ GY L GS + C S + W+ PL C
Sbjct: 993 ----GAVVTLECEDGYMLEGSPQSQCQSDHQ--WNPPLAVC 1027
Score = 59.7 bits (143), Expect = 5e-08
Identities = 206/1028 (20%), Positives = 342/1028 (33%), Gaps = 189/1028 (18%)
Query: 520 SCGDPGIPAYGRRE--GSRFHHGDTLKFECQPAFELVGQKAITC----QKNNQWSAKKPG 573
SCG P GR + G +++ C F L+G+K++ C + + W P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 574 CVFSCFFNFTS------PSGVVLSPNYPEDYGNHLH--CVWLILARPESRIHLAFNDIDV 625
C + F ++S P G + + P +G+ + C + N++
Sbjct: 82 CEY--FNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWG 139
Query: 626 EPQFDFLV------------IKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHS 673
+ V I +G V G + S S + + S
Sbjct: 140 PTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLS 199
Query: 674 TGKRGFNITFTTFRHNECPDPGVPVNGK-RFGDSLQLGSSISFLCDEGFLGTQGSETITC 732
+GK ++ T C G NGK + L++G + +F CDEG+ QG + C
Sbjct: 200 SGK--WSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYR-LQGPPSSRC 256
Query: 733 VLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKI 792
V+ V W + CE I P P + G +
Sbjct: 257 VIAGQGVAWTKMPV-CEE------------IFCPSPPPILNGRHIGNSLANVSYGSIVTY 303
Query: 793 TFDRFKTE-VNYDTLEVRDGR-TYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSD 850
T D E VN+ + R T + G + G P+ +STS + H
Sbjct: 304 TCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGP-APRCELSTS-------AVQCPHPQ 355
Query: 851 IGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPN 910
I LR ++ Q D + V F+C G+TL + + C
Sbjct: 356 I---LRGRMVSGQKDR----------------YTYNDTVIFACMFGFTLKGSKQIRCNAQ 396
Query: 911 FQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFH 970
W + P CE C P+ ++ G + ++ + +
Sbjct: 397 GTWEPSAPVCEKEC-------------QAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGY 443
Query: 971 LESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFI-SDFSMSY-EGFN 1028
+ G + + T G +T P+ Q ++ A + G Q +F+ D + S EG+
Sbjct: 444 VLVGEESIQCTSEGVWTPPVPQ---CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYK 500
Query: 1029 ITFSEY-----------DLEPCEEPEVP--------AYSIRKGLQFGVGDTLTFSCFPG- 1068
++ S Y ++ C+E P A++ F G T+T++C PG
Sbjct: 501 LSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGP 560
Query: 1069 -----YRLEGTARITCLGG--RRRLWSSPLPRC-----VAECGNSVTGTQGTLLSPNFPV 1116
+ L G + I C R WS P P C +C + + P
Sbjct: 561 ERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPY 620
Query: 1117 NYNN--NHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMG 1174
YN+ +C YS T G Q++ +A + ++ G + L H G
Sbjct: 621 FYNDTVTFKC-YSGFTLKGSS-QIRCKADNTWDPEIPVCEKGCQSPPGL----HHGRHTG 674
Query: 1175 VTLNSTSSSLWLDFITDAENTSKGFE-LHFSSFELIKCEDPGTPKFGYKVHD--EGHFAG 1231
S + +D+ D G + +H P + V + AG
Sbjct: 675 GNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQELPAG 734
Query: 1232 SSVSF---SCDPGYSLRGSEELLCLSGERRTWDRPLPTC-VAECGG---TVRGEVSGQVL 1284
S V SC GY L G +C E W + +P C V C V G+ +G +
Sbjct: 735 SRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMA 794
Query: 1285 SPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLR---IWDGPVESGVLLKE 1341
N ++ E C G + L + + W GP +
Sbjct: 795 E-----------NFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPP 843
Query: 1342 LSGPALPKDLHS-TFNSVVLQFSTD---FFTSKQGFAIQFSVSTATSCND-----PGIP- 1391
++ P+ H N +S + + GF + + S C+ PG+P
Sbjct: 844 VTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIM--NGSRVIRCHTDNTWVPGVPT 901
Query: 1392 ---------------QNGSRSGDS---WEAGDSTVFQCDPGYALQGSAEISCVKIENRFF 1433
NG+ +G + + G S ++ CD GY L G A + C +
Sbjct: 902 CIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCT---HEGT 958
Query: 1434 WQPSPPTC 1441
W P C
Sbjct: 959 WSQPAPHC 966
Score = 58.5 bits (140), Expect = 1e-07
Identities = 138/648 (21%), Positives = 224/648 (34%), Gaps = 119/648 (18%)
Query: 359 FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITS 418
F G+S++++CN GY L G + I C W+ P C+ C+A R ++T
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEG----VWTPPVPQCKVAACEATGRQ---LLTK 481
Query: 419 PNFP-IQYDNNAHC------------------VWI--------ITALNPSKVIKLAFEEF 451
P ++ D N+ C W IT P + A
Sbjct: 482 PQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGS 541
Query: 452 DLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKA 511
LE TV G ++ V + L G S + ++N Q + SG + K
Sbjct: 542 SLEDFPYGTTVTYTCNPGPERGVEFSLIGEST--IRCTSNDQE----RGTWSGPAPLCKL 595
Query: 512 SYEEIEQGSCGDPGIPAYGRREGSR--FHHGDTLKFECQPAFELVGQKAITCQKNNQWSA 569
S ++ C I + G + + DT+ F+C F L G I C+ +N W
Sbjct: 596 SLLAVQ---CSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDP 652
Query: 570 KKPGCVFSC-----------------FFNFTSPSGVVLSPNYPEDYGNHLHCV----WLI 608
+ P C C FF P Y +HC+ W
Sbjct: 653 EIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSP 712
Query: 609 LA-RPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLE 667
A R E + P G+ E G QL +GH ++
Sbjct: 713 SAPRCEETCQHVRQSLQELPA--------GSRVELVNTSCQDGYQL------TGHAYQM- 757
Query: 668 FQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFG---DSLQLGSSISFLCDEGFLGT 724
D G I H C P V VNGK G ++ G+ +S+ CD+GF
Sbjct: 758 -CQDAENGIWFKKIPLCKVIH--CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFY-L 813
Query: 725 QGSETITCVL-KEGSVVWNSAVLRC-EAPCGGHLTSPS---GTILSPGWPGFYKDALSCA 779
G + + C +G W+ +C +P +P G L+ + + +
Sbjct: 814 LGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIV-- 871
Query: 780 WVIEAQPGYPIK----ITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTS 835
++ PG+ + I T V ++ P +G + S
Sbjct: 872 -YVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFS 930
Query: 836 NYLYLLFSTDKSHSDIGFQL----RYETITLQSDHCLDPGIP----VNGQRHGND----F 883
+ +L+S D+ + +G L T + + HC + ++G + G + +
Sbjct: 931 PGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMY 990
Query: 884 YVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEA------LCG 925
GA+VT C+ GY L +C+ + QW+ L C + LCG
Sbjct: 991 QYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 1038
Score = 55.5 bits (132), Expect = 9e-07
Identities = 185/897 (20%), Positives = 292/897 (32%), Gaps = 198/897 (22%)
Query: 540 GDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFS-CFFNFTSPSGVVLSP------ 592
G ++ + C+ + LVG+K I C + +WSA P C + C P+G V P
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVG 235
Query: 593 ---NYPEDYGNHLHCVWLILARPESRIHLAFNDI--DVEPQFDFLVIKDGATAEAPVL-G 646
N+ D G L P SR +A + P + + + P+L G
Sbjct: 236 VTANFFCDEGYRLQ------GPPSSRCVIAGQGVAWTKMPVCEEIF----CPSPPPILNG 285
Query: 647 TFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHN----------------- 689
GN L + S G + D G I +T R
Sbjct: 286 RHIGNSLAN--VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCE 343
Query: 690 ------ECPDP----GVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSV 739
+CP P G V+G++ D ++ F C GF +GS+ I C
Sbjct: 344 LSTSAVQCPHPQILRGRMVSGQK--DRYTYNDTVIFACMFGFT-LKGSKQIRC---NAQG 397
Query: 740 VWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKT 799
W + CE C P ++ PG IK + +
Sbjct: 398 TWEPSAPVCEKECQAP-------------PNILNGQKEDRHMVRFDPGTSIKYSCNPGYV 444
Query: 800 EVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDI-------- 851
V ++++ ++ P VPQ ++ T H +
Sbjct: 445 LVGEESIQCTSEGVWTPP---------VPQCKVAACEATGRQLLTKPQHQFVRPDVNSSC 495
Query: 852 --GFQLR--------------YETITLQSDHCLDPGIPVNGQRHGN---DFYVGALVTFS 892
G++L E + C P + NG G+ DF G VT++
Sbjct: 496 GEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYT 555
Query: 893 CDSG------YTLSDGEPLECEPNFQ----WSRALPSCE-----ALCGGFIQGSSGTILS 937
C+ G ++L + C N Q WS P C+ C + I
Sbjct: 556 CNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISG 615
Query: 938 PGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSR 997
P FY + + F + F L+ +N + G +
Sbjct: 616 KEAPYFYNDTVT-------------FKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQ 662
Query: 998 LPAPISAGLY--GNFTAQVRFISDFSMSYE---GFNITFSEY-----------DLEPCEE 1041
P + G + GN V F+S ++ Y G+ + ++ CEE
Sbjct: 663 SPPGLHHGRHTGGN---TVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEE 719
Query: 1042 PEVPAYSIRKGLQ-FGVG---DTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRC-VA 1096
+R+ LQ G + + SC GY+L G A C +W +P C V
Sbjct: 720 T---CQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVI 776
Query: 1097 ECGNS---VTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKV 1153
C V G +++ NF ++EC K +L+ R+ G
Sbjct: 777 HCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEK--KLQCRSDSKGHGSWSGP 834
Query: 1154 YDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCED 1213
S + + G LN T S+ + I + + GF ++ S +I+C
Sbjct: 835 SPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVD-CNPGFIMNGS--RVIRCHT 891
Query: 1214 PGT-------------------PKFGYKVHDEGHFA----GSSVSFSCDPGYSLRGSEEL 1250
T PK H G+ A G S+ +SCD GY L G L
Sbjct: 892 DNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALL 951
Query: 1251 LCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAG 1307
LC TW +P P C E + ++ G + G + + T+E E G
Sbjct: 952 LCT--HEGTWSQPAPHC-KEVNCSSPADMDG--IQKGLEPRKMYQYGAVVTLECEDG 1003
Score = 54.7 bits (130), Expect = 2e-06
Identities = 109/476 (22%), Positives = 164/476 (34%), Gaps = 98/476 (20%)
Query: 1557 SCFDPGSIKNG--TRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPV 1614
SC P I NG + + + +G+ + Y C G + + G +L CI W+ P P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 1615 C------------TAPCGGQYVGS------DGVVLS--PNYPQNYTSGQIC----LYFVT 1650
C P G + GS D V + N+ N C ++ T
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 1651 VPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLS---SLSGSHTGESLPLATSNQVLI 1707
V + F + +H+GH + S LS +++ ES L +++
Sbjct: 142 RLPTCV-----SVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIIN 196
Query: 1708 KFSAKGLAPARGFHFVYQAVPRT-SATQCSSVPEPRYGK-RLGSDFSVGAIVRFECNSGY 1765
S+ + AVP T +C S+ GK + VG F C+ GY
Sbjct: 197 CLSSG----------KWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGY 246
Query: 1766 ALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWK 1825
LQG P C+ + G W P C I P P P LN +
Sbjct: 247 RLQGPPSSRCV-IAGQGVAW-TKMPVC------------EEIFCPS-PPPILNGRH---- 287
Query: 1826 IVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLH 1885
G + VS+ + + + N + + S TV + T +
Sbjct: 288 ------IGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPR 341
Query: 1886 FYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTG--ERYLVNDVVSFQCEPGYALQG 1943
++S SA CP P + + +G +RY ND V F C G+ L+G
Sbjct: 342 --CELSTSAV------------QCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKG 387
Query: 1944 HAHISC-MPGTVRRWNYPPPLCIAQC-------GGTVEEMEGVILSPGFPGNYPSN 1991
I C GT W P+C +C G E+ V PG Y N
Sbjct: 388 SKQIRCNAQGT---WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCN 440
Score = 53.1 bits (126), Expect = 5e-06
Identities = 117/549 (21%), Positives = 190/549 (34%), Gaps = 117/549 (21%)
Query: 87 PQPENLRTRLTGFQLP------ATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCG 140
P P+ LR R+ Q I + +L+ +AQG + C
Sbjct: 352 PHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQ 411
Query: 141 NPGRLPNGIQQGS---TFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCR 197
P + NG ++ F+ G ++YSCN G+ L G + C + W P+P C+
Sbjct: 412 APPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQC----TSEGVWTPPVPQCK 467
Query: 198 ADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLE 257
AC T G+ + H N+ C G+ L G + E
Sbjct: 468 V-AACEAT--GRQLLTKPQHQFVRPDVNSSC--------GEGYKL--------SGSVYQE 508
Query: 258 VTGTEGSSLWFTGASL-------PAPVISSKNWLRLHFTSDGNHRQRGFSAQYQV----K 306
GT WF L P PVI + H S G + Y +
Sbjct: 509 CQGT---IPWFMEIRLCKEITCPPPPVI----YNGAHTGSSLEDFPYGTTVTYTCNPGPE 561
Query: 307 KQIELKSRGVKLMPSKDNSQKTSV---------LTQVGVSQGHNMCPDPGIPERGKRLGS 357
+ +E G + N Q+ L+ + V H + G GK +
Sbjct: 562 RGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIAN-GYKISGKE--A 618
Query: 358 DFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDA--------HL 409
+ +V F C G+ L+GS +I C + W PVC + C + H
Sbjct: 619 PYFYNDTVTFKCYSGFTLKGSSQIRCKADN----TWDPEIPVCE-KGCQSPPGLHHGRHT 673
Query: 410 RGPSGIITS---------PNFPIQYDNNAHCV----WIITALNPSKVIKLAFEEF-DLER 455
G + S P + + + + HC+ W +A + + + +L
Sbjct: 674 GGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQELPA 733
Query: 456 GYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEE 515
G V QDG Y LTG + +QM + + + FK
Sbjct: 734 GSRVELVNTSCQDG------YQLTGHA---------YQM-----CQDAENGIWFK-KIPL 772
Query: 516 IEQGSCGDPGIPAYGRREG---SRFHHGDTLKFECQPAFELVGQKAITCQKNNQ----WS 568
+ C P + G+ G F +G+ + +EC F L+G+K + C+ +++ WS
Sbjct: 773 CKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWS 832
Query: 569 AKKPGCVFS 577
P C+ S
Sbjct: 833 GPSPQCLRS 841
Score = 49.3 bits (116), Expect = 7e-05
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 499 QTDGSGSSLGFKASYEEIEQGSCGDPGIPA-YGRREGSRFHHGDTLKFECQPAFELVGQK 557
+ DG+ K Y + SC +P +P Y R + + HGD++ F C+ F + G K
Sbjct: 70 KVDGTWDKPAPKCEYFN-KYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNK 128
Query: 558 AITCQKNNQWS-AKKPGCV 575
++ CQ NN W + P CV
Sbjct: 129 SVWCQANNMWGPTRLPTCV 147
Score = 45.8 bits (107), Expect = 7e-04
Identities = 108/506 (21%), Positives = 169/506 (33%), Gaps = 139/506 (27%)
Query: 137 HTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
HT N G + G+ V YSC G+ L G ++ C + S W P+C
Sbjct: 165 HTSENVGSIAPGLS----------VTYSCESGYLLVGEKIINCLS----SGKWSAVPPTC 210
Query: 197 RADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFL 256
+ C R +G + P + +G T +F ++GY
Sbjct: 211 E-EARCKSLGRFPNGKVKEPP---------------ILRVGVTA-----NFFCDEGY--- 246
Query: 257 EVTGTEGSSLWFTGASL---------------PAPVISSKNWLRLHFTSDGNHRQRGFSA 301
+ G S G + P P+++ + H + + G
Sbjct: 247 RLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGR-----HIGNSLANVSYGSIV 301
Query: 302 QYQV----KKQIELKSRGVKLMPSKDNSQKTSVLT----QVGVSQGHNMCPDPGIPERGK 353
Y ++ + G + +SQKT + + +S CP P I RG+
Sbjct: 302 TYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQIL-RGR 360
Query: 354 RLGSD---FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLR 410
+ + +V F C G+ L+GSK+I C + W PVC + C A
Sbjct: 361 MVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRC----NAQGTWEPSAPVCE-KECQA--- 412
Query: 411 GPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGD 470
PN + H V +P IK + GY + G++
Sbjct: 413 -------PPNILNGQKEDRHMV----RFDPGTSIK-----YSCNPGYVLV-----GEESI 451
Query: 471 QKTVLYILTGTSVPDLIVS----------TNHQMWLLFQTDGSGSSLGFKAS---YEEIE 517
Q T + T VP V+ T Q + S G+K S Y+E +
Sbjct: 452 QCTSEGVWT-PPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQ 510
Query: 518 -------------QGSCGDPGIPAYGRREGSR---FHHGDTLKFECQPA------FELVG 555
+ +C P + G GS F +G T+ + C P F L+G
Sbjct: 511 GTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIG 570
Query: 556 QKAITCQKNNQ----WSAKKPGCVFS 577
+ I C N+Q WS P C S
Sbjct: 571 ESTIRCTSNDQERGTWSGPAPLCKLS 596
Score = 44.7 bits (104), Expect = 0.002
Identities = 66/282 (23%), Positives = 100/282 (35%), Gaps = 46/282 (16%)
Query: 139 CGNPGRLPNGIQQG---STFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
C P + NG G F G++V Y C+ GF+L G L C + S+ +W P P
Sbjct: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
Query: 196 CRAD---DACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG 252
C C ++ H S Y +N +V++D
Sbjct: 838 CLRSPPVTRCPNPEVKHGYKLNKTH--SAYSHN---------------DIVYVDCNPGFI 880
Query: 253 YDFLEVTGTEGSSLWFTGASLPAPVISSKNWLRL---HFTSDGNHR-------QRGFSAQ 302
+ V + W G P K ++ T +GNH G S
Sbjct: 881 MNGSRVIRCHTDNTWVPG----VPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSIL 936
Query: 303 YQVKKQIELKSRGVKLMPSKDN-SQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRL 361
Y + L + L + SQ +V S +M GI ++G ++
Sbjct: 937 YSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADM---DGI-QKGLEPRKMYQY 992
Query: 362 GSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRAR 403
G+ V C +GY L+GS + C SD W+ VCR+R
Sbjct: 993 GAVVTLECEDGYMLEGSPQSQCQ--SD--HQWNPPLAVCRSR 1030
Score = 43.9 bits (102), Expect = 0.003
Identities = 54/222 (24%), Positives = 81/222 (36%), Gaps = 47/222 (21%)
Query: 360 RLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSP 419
R+G + F C+EGY LQG C+ ++ AW+ PVC C + P I+
Sbjct: 233 RVGVTANFFCDEGYRLQGPPSSRCV-IAGQGVAWT-KMPVCEEIFCPS----PPPILNGR 286
Query: 420 NFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILT 479
+ N ++ + +P D E G + + +G+ + TV T
Sbjct: 287 HIGNSLANVSYGSIVTYTCDP-----------DPEEGVNFILIGESTL---RCTVDSQKT 332
Query: 480 GTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRR---EGSR 536
GT W SG + + S ++ C P I GR + R
Sbjct: 333 GT-------------W-------SGPAPRCELSTSAVQ---CPHPQI-LRGRMVSGQKDR 368
Query: 537 FHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSC 578
+ + DT+ F C F L G K I C W P C C
Sbjct: 369 YTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKEC 410
Score = 40.8 bits (94), Expect = 0.024
Identities = 24/61 (39%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
Query: 138 TCGNPGRLPNG-IQQGST-FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
+CG+P + NG I ST +G +RYSC+ F L G L C + TWD P P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 196 C 196
C
Sbjct: 82 C 82
Score = 39.3 bits (90), Expect = 0.069
Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 2/66 (3%)
Query: 2113 PGCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWD 2172
P C+ D + G+ Y G VT EC GY L G P CQ ++ W+
Sbjct: 964 PHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQ--SDHQWN 1021
Query: 2173 HPLPKC 2178
PL C
Sbjct: 1022 PPLAVC 1027
Score = 35.8 bits (81), Expect = 0.76
Identities = 16/45 (35%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
Query: 340 HNMCPDPGIPERGKRLGSD-FRLGSSVQFTCNEGYDLQGSKRITC 383
++ CP+P +P K GS +R G SV F C + + G+K + C
Sbjct: 88 YSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWC 132
Score = 34.3 bits (77), Expect = 2.2
Identities = 19/68 (27%), Positives = 28/68 (41%), Gaps = 7/68 (10%)
Query: 343 CPDPGIPERGKRLGSD---FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPV 399
CP P G G + F G S+ ++C++GY L G + C WS P
Sbjct: 910 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHE----GTWSQPAPH 965
Query: 400 CRARMCDA 407
C+ C +
Sbjct: 966 CKEVNCSS 973
Score = 33.9 bits (76), Expect = 2.9
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 1902 KTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPP 1961
K V SS + G++ + Y VV+ +CE GY L+G C + +WN P
Sbjct: 967 KEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQ--SDHQWNPPL 1024
Query: 1962 PLC 1964
+C
Sbjct: 1025 AVC 1027
Score = 32.7 bits (73), Expect = 6.5
Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 8/65 (12%)
Query: 135 PSHTCGNPGRLPNGIQQGST---FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDF 191
P C NP + +G + T ++ D V CN GF + G V+ CH + TW
Sbjct: 843 PVTRCPNP-EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDN----TWVP 897
Query: 192 PLPSC 196
+P+C
Sbjct: 898 GVPTC 902
>gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens]
Length = 993
Score = 271 bits (693), Expect = 8e-72
Identities = 218/761 (28%), Positives = 328/761 (43%), Gaps = 82/761 (10%)
Query: 1049 IRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGT 1108
+ +G G+ T+T S G E T T + +P P C + +G +G+
Sbjct: 200 VSQGAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGP-----CSWNFSGPEGS 254
Query: 1109 LLSP-NFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGVF 1167
L SP + + +C + I PG G+++K + L EG+ + V +G L
Sbjct: 255 LDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV-EGLGGPDPLPLAN 313
Query: 1168 SHSEMMGVTLNSTSSSLWLDFITDAENTSKG-FELHFSSFELIKCEDPGTPKFGYKVHDE 1226
+ G + S + L F + G F H+ ++ L+ C P P +G
Sbjct: 314 QSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAY-LLSCHFPRRPAYGDVTVTS 372
Query: 1227 GHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSP 1286
H G S F C GY L+G+ L CL+ + WD P C+A CGG +R +G+++SP
Sbjct: 373 LH-PGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSP 431
Query: 1287 GYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGP-VESGVLLKELSGP 1345
G+P Y +NL C W +EA G + LHF E D L I +G VE+ +
Sbjct: 432 GFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVE 491
Query: 1346 ALP-KDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQ-NGSRSGDSWEA 1403
LP + L S+ ++ STD + G A+++ C +P + N S S ++
Sbjct: 492 YLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPV 551
Query: 1404 GDSTVFQCDPGYAL-QGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYP 1462
G + F CDPGY L QGS I CV + W + P C A C G++T +GV+LSPN+P
Sbjct: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDP-QWNETEPACRAVCSGEITDSAGVVLSPNWP 610
Query: 1463 EPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPG 1522
EPY G++C W V V D I L + + PG D L YDG D + ++G + G +
Sbjct: 611 EPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHF 669
Query: 1523 RIESSSNSLFLAFRSDASVS----NAGFVIDYTENPR-ESCFDPGSIKNGTRVGSDLKL- 1576
++ +S + + F+SD S GFVI + E PR ++C + I NG + S +L
Sbjct: 670 KLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELV 729
Query: 1577 -GSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVC--TAPC--GGQYVGSDGVVL 1631
G+ VTY C+ GY+V G+S L C W+ P C C G S ++
Sbjct: 730 HGTVVTYQCYPGYQVVGSSVLMC----QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLIS 785
Query: 1632 SPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGS 1691
SP +P T IC + +V+ G + ++ HD +
Sbjct: 786 SPKFPVGATVQYIC------DQGFVLMG---------SSILTCHDRQA---------GSP 821
Query: 1692 HTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSDF 1751
+ P Q L P G + P A P
Sbjct: 822 KWSDRAPKCLLEQ---------LKPCHGL-----SAPENGARSPEKQLHP---------- 857
Query: 1752 SVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC 1792
GA + F C GY L+G I+C VPG + W+ P C
Sbjct: 858 -AGATIHFSCAPGYVLKGQASIKC--VPGHPSHWSDPPPIC 895
Score = 207 bits (526), Expect = 2e-52
Identities = 197/726 (27%), Positives = 300/726 (41%), Gaps = 106/726 (14%)
Query: 578 CFFNFTSPSGVVLSP---NYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVI 634
C +NF+ P G + SP + P D G L C + I P + + +I +
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVG--LDCFFYISVYPGYGVEIKVQNIS---------L 292
Query: 635 KDGATAEAPVLGTFSGNQLPSS----------ITSSGHVARLEFQT-DHSTGKRGFNITF 683
++G T LG + LP + I S H A L FQ+ G F+ +
Sbjct: 293 REGETVTVEGLG--GPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHY 350
Query: 684 TTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNS 743
+ + C P P G SL G S F C G+ +G+ +TC L W+S
Sbjct: 351 QAYLLS-CHFPRRPAYGDVTVTSLHPGGSARFHCATGYQ-LKGARHLTC-LNATQPFWDS 407
Query: 744 AVLRCEAPCGGHL-TSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN 802
C A CGG + + +G I+SPG+PG Y + L+C W++EA G + + F++ +
Sbjct: 408 KEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAED 467
Query: 803 YDTLEVRDGRTYSAPLI-GVYHGTQVP-QFLISTSNYLYLLFSTDKSHSDIGFQLRYETI 860
D L +R+G AP + Y +P + L+S+ + ++ STD S + G LRYE
Sbjct: 468 DDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAF 527
Query: 861 TLQSDHCLDPGIPVNGQRHGNDFY-VGALVTFSCDSGYTLSDGEPL-EC-EPNF-QWSRA 916
Q HC +P + Y VG V FSCD GYTL G + EC +P+ QW+
Sbjct: 528 --QQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNET 585
Query: 917 LPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHD 976
P+C A+C G I S+G +LSP +P+ Y +C W + K + + G D
Sbjct: 586 EPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-D 644
Query: 977 YLLITENGSFT-QPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMS----YEGFNITF 1031
L + T + L Q +G R + + ++F SD S +GF I F
Sbjct: 645 VLTFYDGDDLTARVLGQYSGPRSHFKLFTSM---ADVTIQFQSDPGTSVLGYQQGFVIHF 701
Query: 1032 SEYDL-EPCEE-PEVP-AYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWS 1088
E + C E PE+P + + G +T+ C+PGY++ G++ + C WS
Sbjct: 702 FEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWS 759
Query: 1089 SPLPRC--VAECGN--SVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFE 1144
LP C V C + V ++ + SP FPV + C + F
Sbjct: 760 EDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYIC---------------DQGFV 804
Query: 1145 LSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFS 1204
L +L +D S W D
Sbjct: 805 LMGSSILTCHD----------------------RQAGSPKWSDRAPKC-----------L 831
Query: 1205 SFELIKCEDPGTPKFGYKVHDEG-HFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRP 1263
+L C P+ G + ++ H AG+++ FSC PGY L+G + C+ G W P
Sbjct: 832 LEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDP 891
Query: 1264 LPTCVA 1269
P C A
Sbjct: 892 PPICRA 897
Score = 201 bits (511), Expect = 1e-50
Identities = 155/555 (27%), Positives = 244/555 (43%), Gaps = 26/555 (4%)
Query: 405 CDAHLRGPSGIITSP-NFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVG 463
C + GP G + SP + D C + I+ P +++ + L G G
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVY-PGYGVEIKVQNISLREGETVTVEG 302
Query: 464 DGGQDG-DQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCG 522
GG D ++L G +I S HQ L FQ+ + G + + SC
Sbjct: 303 LGGPDPLPLANQSFLLRG----QVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCH 358
Query: 523 DPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQ--WSAKKPGCVFSCFF 580
P PAYG + H G + +F C ++L G + +TC Q W +K+P C+ +C
Sbjct: 359 FPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGG 418
Query: 581 NF-TSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGAT 639
+ +G ++SP +P +Y N+L C WL+ A R+HL F + + D L+I++G
Sbjct: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDN 478
Query: 640 AEA-PVLGTFSGNQLP-SSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVP 697
EA PV ++ LP + SSG +E TD S G + + F+ C +P V
Sbjct: 479 VEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVK 538
Query: 698 V-NGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHL 756
N + +G+++ F CD G+ QGS I CV WN C A C G +
Sbjct: 539 YGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV-DPHDPQWNETEPACRAVCSGEI 597
Query: 757 TSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSA 816
T +G +LSP WP Y C W + + I + + D L DG +A
Sbjct: 598 TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTA 656
Query: 817 PLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQ---SDHCLD-PGI 872
++G Y G + L ++ + + F +D S +G+Q + + +D C + P I
Sbjct: 657 RVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEI 716
Query: 873 PVNGQRHGN--DFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCG----G 926
P NG + + + G +VT+ C GY + L C+ + WS LPSC+ + G
Sbjct: 717 P-NGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPG 775
Query: 927 FIQGSSGTILSPGFP 941
++ S I SP FP
Sbjct: 776 DVEHSRRLISSPKFP 790
Score = 194 bits (494), Expect = 1e-48
Identities = 170/605 (28%), Positives = 253/605 (41%), Gaps = 85/605 (14%)
Query: 1384 SCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIA 1443
SC+ P P G + S G S F C GY L+G+ ++C+ F W P CIA
Sbjct: 356 SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPF-WDSKEPVCIA 414
Query: 1444 PCGGDL-TGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIY 1502
CGG + +G I+SP +P Y C W + + L F +L D L I
Sbjct: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIR 474
Query: 1503 DGRD-SLSPLIGSFYGSQLPGR-IESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFD 1560
+G + P+ S+ LP + SS F+ +D+S + AG + Y + C++
Sbjct: 475 NGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYE 534
Query: 1561 PGSIKNGTRVGSD--LKLGSSVTYYCHGGYEVE-GTSTLSCILGPDGKPVWNNPRPVCTA 1617
P +K G S +G++V + C GY +E G+ + C+ D P WN P C A
Sbjct: 535 P-FVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHD--PQWNETEPACRA 591
Query: 1618 PCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDG 1677
C G+ S GVVLSPN+P+ Y GQ C++ V V +D + DV+ +DG
Sbjct: 592 VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDG 651
Query: 1678 HSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSA----KGLAPARGFHFVYQAVPRTSAT 1733
+R+L SG + L + V I+F + L +GF + VPR
Sbjct: 652 DDLTARVLGQYSGPRSHFKL-FTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDT- 709
Query: 1734 QCSSVPEPRYGKRLGS--DFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVS--- 1788
C +PE G + S + G +V ++C GY + GS + C QW+++
Sbjct: 710 -CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMC--------QWDLTWSE 760
Query: 1789 -APTC--VVPC--GGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVT 1843
P+C V C G++ R I SP FP G +Q +
Sbjct: 761 DLPSCQRVTSCHDPGDVEHSRRLISSPKFP------------------VGATVQYI---- 798
Query: 1844 EQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 1903
D ++GS ++L Q +SD A LE
Sbjct: 799 ------------CDQGFVLMGS-------SILTCHDRQAGSPKWSD---RAPKCLLEQ-- 834
Query: 1904 VGLSSCPEPAVPSNGVKTGERYL--VNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPP 1961
L C + P NG ++ E+ L + F C PGY L+G A I C+PG W+ PP
Sbjct: 835 --LKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPP 892
Query: 1962 PLCIA 1966
P+C A
Sbjct: 893 PICRA 897
Score = 190 bits (482), Expect = 2e-47
Identities = 175/637 (27%), Positives = 257/637 (40%), Gaps = 75/637 (11%)
Query: 1587 GYEVEGTSTLSCILGPDGKPVWNNPRPVCT-------APCGGQYVGSDGVVLSPNYPQNY 1639
G ++GT T S G D + T PC + G +G + SP +
Sbjct: 205 GIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGPCSWNFSGPEGSLDSPTDLSSP 264
Query: 1640 TS-GQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLP 1698
T G C ++++V Y V + + V V L++ S G+ +
Sbjct: 265 TDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQSFLLRGQVIR 324
Query: 1699 LATSNQVLIKFSAKGLAPARG---FHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGA 1755
T +Q ++F + L P G FHF YQA C P YG + G
Sbjct: 325 SPT-HQAALRFQS--LPPPAGPGTFHFHYQAY----LLSCHFPRRPAYGDVTVTSLHPGG 377
Query: 1756 IVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERR-GTILSPGFPE 1814
RF C +GY L+G+ + CL W+ P C+ CGG + G I+SPGFP
Sbjct: 378 SARFHCATGYQLKGARHLTCLNATQPF--WDSKEPVCIAACGGVIRNATTGRIVSPGFPG 435
Query: 1815 PYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVT--MLGSFSGTTVP 1872
Y N+L C W + PEG + + ++ D L + +G DN + S+ +P
Sbjct: 436 NYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNG-DNVEAPPVYDSYEVEYLP 494
Query: 1873 AL-LNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVP-SNGVKTGERYLVNDV 1930
L S+ ++ +D S +AAG L Y+ C EP V N + Y V
Sbjct: 495 IEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTT 554
Query: 1931 VSFQCEPGYAL-QGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVILSPGFPGNYP 1989
V F C+PGY L QG I C+ +WN P C A C G + + GV+LSP +P Y
Sbjct: 555 VEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYG 614
Query: 1990 SNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELPSSLLS 2049
DC W + + + P D + +G T+R++G++SG L +
Sbjct: 615 RGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHFKLFT 673
Query: 2050 TSHETTVYFHSDHSQNRPGFK-LEYQDLTYSHQISSFLRGFDLSELERTNSTPPVAASYV 2108
+ + T+ F SD PG L YQ H E+ R ++ P
Sbjct: 674 SMADVTIQFQSD-----PGTSVLGYQQGFVIH----------FFEVPRNDTCP------- 711
Query: 2109 WDLDPGCEAYELQECPD--PEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHG 2166
EL E P+ P +V G VT++C PGYQ+ G VL CQ
Sbjct: 712 ----------ELPEIPNGWKSPSQPELVHGT------VVTYQCYPGYQVVGSSVLMCQ-- 753
Query: 2167 TNRNWDHPLPKCE--VPC--GGNITSSNGTVYSPGFP 2199
+ W LP C+ C G++ S + SP FP
Sbjct: 754 WDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 790
Score = 180 bits (456), Expect = 3e-44
Identities = 153/564 (27%), Positives = 247/564 (43%), Gaps = 38/564 (6%)
Query: 1444 PCGGDLTGPSGVILSP-NYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIY 1502
PC + +GP G + SP + P G +C + ++V P Y + + +L G
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVT--V 300
Query: 1503 DGRDSLSPLIGSFYGSQLPGR-IESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDP 1561
+G PL + L G+ I S ++ L F+S + G + + SC P
Sbjct: 301 EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFP 360
Query: 1562 GSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGG 1621
G + L G S ++C GY+++G L+C+ +P W++ PVC A CGG
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNAT--QPFWDSKEPVCIAACGG 418
Query: 1622 QYVGSD-GVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDV-VEVHDGHS 1679
+ G ++SP +P NY++ C + + P+ + F A +D + + +G +
Sbjct: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDN 478
Query: 1680 QHSRLLSSLSGSHTGESLP----LATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQC 1735
+ + S+ E LP L++ ++ S A G Y+A + +
Sbjct: 479 VEA---PPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYE- 534
Query: 1736 SSVPEPRYGKRLGSD--FSVGAIVRFECNSGYAL-QGSPEIECLPVPGALAQWNVSAPTC 1792
P +YG S + VG V F C+ GY L QGS IEC+ QWN + P C
Sbjct: 535 ---PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDP--QWNETEPAC 589
Query: 1793 VVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEV 1852
C G +T+ G +LSP +PEPY +C+W + V E I + + + D L
Sbjct: 590 RAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLD-IRVLRIGPGDVLTF 648
Query: 1853 FDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLE-----YKTVGLS 1907
+DG D T +LG +SG L ++ + + F SD S G+ ++
Sbjct: 649 YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRND 708
Query: 1908 SCPE-PAVPSNGVKTGERYLVN-DVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLC- 1964
+CPE P +P+ + LV+ VV++QC PGY + G + + C W+ P C
Sbjct: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLT--WSEDLPSCQ 766
Query: 1965 -IAQC--GGTVEEMEGVILSPGFP 1985
+ C G VE +I SP FP
Sbjct: 767 RVTSCHDPGDVEHSRRLISSPKFP 790
Score = 176 bits (445), Expect = 5e-43
Identities = 162/583 (27%), Positives = 240/583 (41%), Gaps = 37/583 (6%)
Query: 2096 RTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQL 2155
R S PP A + +AY L C P A G V + G S F C GYQL
Sbjct: 333 RFQSLPPPAGPGTFHFH--YQAY-LLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQL 389
Query: 2156 TGHPVLTCQHGTNRNWDHPLPKCEVPCGGNI-TSSNGTVYSPGFPSPYSSSQDCVWLITV 2214
G LTC + T WD P C CGG I ++ G + SPGFP YS++ C WL+
Sbjct: 390 KGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEA 449
Query: 2215 PIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRL--GVFTRSMAKKTVQSSSNQVLLKF 2272
P G + L+ + D + I +G AP + + + + SS ++
Sbjct: 450 PEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVEL 509
Query: 2273 HRD---AATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTL- 2328
D AA G A+ + A+ C P + + + +G V + C PG+TL
Sbjct: 510 STDSSGAAAG--MALRYEAFQQGHCYEP-FVKYGNFSSSTPTYPVGTTVEFSCDPGYTLE 566
Query: 2329 VGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVR 2388
G+ I+ C Q+ P C C +TDS GV+LS ++P Y + Q C W V
Sbjct: 567 QGSIIIECVDPHDPQWNETEPACRAVCSGE--ITDSAGVVLSPNWPEPYGRGQDCIWGVH 624
Query: 2389 VEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRW 2448
VE D I L + L D +DG + +L SG S + TS ++ V +++
Sbjct: 625 VEEDKRIMLDIR-VLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMAD-VTIQF 682
Query: 2449 SSDHAYN----RKGFKIRY-----SAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGY 2499
SD + ++GF I + + LP P Q G + + C GY
Sbjct: 683 QSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGY 742
Query: 2500 RLVGHSMAICTRHPQGYHLWSEAIPLCQAL-SCGLPEAPKNG--MVFGKEYTVGTKAMYS 2556
++VG S+ +C Q WSE +P CQ + SC P ++ ++ ++ VG Y
Sbjct: 743 QVVGSSVLMC----QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYI 798
Query: 2557 CSEGYHLQAGAEATAECLDTG--LWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQY 2614
C +G+ L + T G WS+R P+C+ +S R + +
Sbjct: 799 CDQGFVLMGSSILTCHDRQAGSPKWSDR--APKCLLEQLKPCHGLSAPENGARSPEKQLH 856
Query: 2615 QFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIIS 2657
A + C PGY GQ I+C D P CR S
Sbjct: 857 PAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAAS 899
Score = 164 bits (416), Expect = 1e-39
Identities = 123/427 (28%), Positives = 189/427 (44%), Gaps = 25/427 (5%)
Query: 343 CPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRA 402
C P P G + G S +F C GY L+G++ +TC+ + F W PVC A
Sbjct: 357 CHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPF--WDSKEPVCIA 414
Query: 403 RMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTV 462
+G I SP FP Y NN C W++ A + + L FE+ L D L +
Sbjct: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQR-LHLHFEKVSLAEDDDRLII 473
Query: 463 GDGGQ-DGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSC 521
+G + Y + + L+ S H ++ TD SG++ G YE +QG C
Sbjct: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKH-FFVELSTDSSGAAAGMALRYEAFQQGHC 532
Query: 522 GDPGIPAYGRREGSR--FHHGDTLKFECQPAFELV-GQKAITC--QKNNQWSAKKPGCVF 576
+P + YG S + G T++F C P + L G I C + QW+ +P C
Sbjct: 533 YEPFVK-YGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRA 591
Query: 577 SCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKD 636
C T +GVVLSPN+PE YG C+W + + RI L + + P D L D
Sbjct: 592 VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYD 650
Query: 637 GATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTF-----RHNEC 691
G A VLG +SG + + +S ++FQ+D T G+ F R++ C
Sbjct: 651 GDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTC 710
Query: 692 PD-PGVPVNGKRFGDSLQL--GSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRC 748
P+ P +P NG + +L G+ +++ C G+ GS + C + + W+ + C
Sbjct: 711 PELPEIP-NGWKSPSQPELVHGTVVTYQCYPGY-QVVGSSVLMC---QWDLTWSEDLPSC 765
Query: 749 EAPCGGH 755
+ H
Sbjct: 766 QRVTSCH 772
Score = 139 bits (351), Expect = 4e-32
Identities = 167/688 (24%), Positives = 268/688 (38%), Gaps = 66/688 (9%)
Query: 2181 PCGGNITSSNGTVYSP-GFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITI- 2238
PC N + G++ SP SP DC + I+V G+GV + + + G+ +T+
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLR-EGETVTVE 301
Query: 2239 -WDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHR--DAATGGIFAIAFSAYPLTKCP 2295
GP L + + + ++S ++Q L+F A G F + AY L C
Sbjct: 302 GLGGPDPLP--LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAY-LLSCH 358
Query: 2296 PPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHC 2355
P +V + + G R+ C G+ L G LTC T ++ P+C C
Sbjct: 359 FPRRPAYGDVTVTS--LHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAAC 416
Query: 2356 PTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFD 2415
+ +TG I+S +PG+Y TC WL+ + L E + D I +
Sbjct: 417 -GGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
Query: 2416 GPSGQS-PLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA---PYCSLP 2471
G + ++ P+ + Y + SS ++ S+D + G +RY A +C P
Sbjct: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
Query: 2472 RAPLHGFILGQTSTQP-GGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALS 2530
+G T T P G ++ F C+ GY L S+ I P W+E P C+A+
Sbjct: 536 FVK-YGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQ-WNETEPACRAV- 592
Query: 2531 CGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCV- 2589
C G+V + C G H++ E LD + + P V
Sbjct: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVE---EDKRIMLDIRV---LRIGPGDVL 646
Query: 2590 ------PVTCPDVSSISVEHGRWRL---IFETQYQFQAQLMLICDPGYYYTGQRVIRCQA 2640
+T + S ++L + + QFQ+ DPG G +
Sbjct: 647 TFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQS------DPGTSVLGYQ------ 694
Query: 2641 NGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLS--VYGATAIFSCNSGYTLVGSRVREC 2698
+ + R +C ELP PNG + + V+G + C GY +VGS V C
Sbjct: 695 --QGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMC 752
Query: 2699 MANGLWSGSEVRC-LAGHCGTPEPIVNGH--INGENYSYRGSVVYQCNAGFRLIGMSVRI 2755
+ WS C C P + + I+ + +V Y C+ GF L+G S+
Sbjct: 753 QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILT 812
Query: 2756 CQQ----DHHWSGKTPFCVLVS---CGHPGSPPHSQMSGDS--YTVGAVVRYSCIGKRTL 2806
C WS + P C+L C +P + S + + GA + +SC L
Sbjct: 813 CHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVL 872
Query: 2807 VGNSTRMC--GLDGHWTGSLPHCSGTSV 2832
G ++ C G HW+ P C S+
Sbjct: 873 KGQASIKCVPGHPSHWSDPPPICRAASL 900
Score = 138 bits (348), Expect = 8e-32
Identities = 150/573 (26%), Positives = 238/573 (41%), Gaps = 65/573 (11%)
Query: 26 CTFQLHGPNGTVESPGFPYGYPNYA-NCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFD 84
C++ GP G+++SP + +C + I+ + +++ Q+ +L E V
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGL 303
Query: 85 GPPQPENLRTRLTGFQLPATIVSAAT-TLSLRLISDYAVSAQG-FHATYEVLPSHTCGNP 142
G P P L + F L ++ + T +LR S + G FH Y+ +C P
Sbjct: 304 GGPDPLPLANQ--SFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFP 360
Query: 143 GRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDAC 202
R G ++ + G R+ C G+ L+G LTC ++ WD P C A AC
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQ--PFWDSKEPVCIA--AC 416
Query: 203 GGTLRGQS-GIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGT 261
GG +R + G I SP FP Y NN C W + A G + L F L + D L +
Sbjct: 417 GGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIR-- 474
Query: 262 EGSSLWFTGASLPAPVISSK---NWLRLH-FTSDGNHRQRGFSAQYQVKKQIELKSRGVK 317
G ++ AP + +L + S G H V+
Sbjct: 475 -------NGDNVEAPPVYDSYEVEYLPIEGLLSSGKH-------------------FFVE 508
Query: 318 LMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGS--DFRLGSSVQFTCNEGYDL 375
L + L QGH C +P + + G S + +G++V+F+C+ GY L
Sbjct: 509 LSTDSSGAAAGMALRYEAFQQGH--CYEPFV-KYGNFSSSTPTYPVGTTVEFSCDPGYTL 565
Query: 376 -QGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWI 434
QGS I C+ D W++ P CRA +C + +G++ SPN+P Y C+W
Sbjct: 566 EQGSIIIECVDPHD--PQWNETEPACRA-VCSGEITDSAGVVLSPNWPEPYGRGQDCIWG 622
Query: 435 ITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQM 494
+ + K I L + G D LT DG D VL +G + ++ +
Sbjct: 623 V-HVEEDKRIMLDIRVLRIGPG-DVLTFYDG--DDLTARVLGQYSGPRSHFKLFTSMADV 678
Query: 495 WLLFQTDGSGSSLGFKAS-----YEEIEQGSCGD-PGIP-AYGRREGSRFHHGDTLKFEC 547
+ FQ+D S LG++ +E +C + P IP + HG + ++C
Sbjct: 679 TIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQC 738
Query: 548 QPAFELVGQKAITCQKNNQWSAKKPGC--VFSC 578
P +++VG + CQ + WS P C V SC
Sbjct: 739 YPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSC 771
Score = 112 bits (279), Expect = 8e-24
Identities = 104/414 (25%), Positives = 167/414 (40%), Gaps = 57/414 (13%)
Query: 35 GTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG-----PPQP 89
G + SPGFP Y N C W + A E R+ L F+ +L ED D L + +G PP
Sbjct: 426 GRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVY 485
Query: 90 ENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNP-GRLPNG 148
++ + ++S+ + L +D + +A G YE C P + N
Sbjct: 486 DSYEVEYLPIE---GLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNF 542
Query: 149 IQQGSTFNLGDKVRYSCNLGFFLE-GHAVLTCHAGSENSATWDFPLPSCRADDACGGTLR 207
T+ +G V +SC+ G+ LE G ++ C + W+ P+CRA C G +
Sbjct: 543 SSSTPTYPVGTTVEFSCDPGYTLEQGSIIIEC--VDPHDPQWNETEPACRA--VCSGEIT 598
Query: 208 GQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG-----YDFLEVTGTE 262
+G++ SP++P Y DC W + E I L ++ G YD ++T
Sbjct: 599 DSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARV 658
Query: 263 GSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVKLMPSK 322
++G + +S + + F SD G+ + + ++ +P
Sbjct: 659 LGQ--YSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEI 716
Query: 323 DNSQKT---------SVLTQ--------VGVS-----------------QGHNMCPDPGI 348
N K+ +V+T VG S Q C DPG
Sbjct: 717 PNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGD 776
Query: 349 PERGKRLGSD--FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVC 400
E +RL S F +G++VQ+ C++G+ L GS +TC WSD P C
Sbjct: 777 VEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKC 830
Score = 100 bits (248), Expect = 3e-20
Identities = 137/569 (24%), Positives = 205/569 (36%), Gaps = 65/569 (11%)
Query: 2655 IISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECM--ANGLWSGSEVRCL 2712
++SC P G T G +A F C +GY L G+R C+ W E C+
Sbjct: 354 LLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCI 413
Query: 2713 AGHCGTPEPIVNGHINGENYSYRGSVVYQCN--------AGFRLIGMSVRICQQDHHWSG 2764
A G G I + S C+ L V + + D
Sbjct: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDR--- 470
Query: 2765 KTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCI--GKRTLVGNSTRMCGLDGHWTG 2822
++ + + +PP DSY V + + GK V ST G G
Sbjct: 471 ----LIIRNGDNVEAPPVY----DSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAA---G 519
Query: 2823 SLPHCSGTSVGVCGDPGIPAHGIRLGDSFDP-GTVMRFSCEAGHVLRGSS---ERTCQAN 2878
G C +P + P GT + FSC+ G+ L S E +
Sbjct: 520 MALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHD 579
Query: 2879 GSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATG---------- 2928
W+ ++P C + G +A VV S +C G +
Sbjct: 580 PQWNETEPACRAVCSGE--ITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRV 637
Query: 2929 LLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHR 2988
L V + G D V+ G P + +L + T+ +Q PG + ++
Sbjct: 638 LRIGPGDVLTFYDGDDLTARVL--GQYSGPRSHFKLFTSMA-DVTIQFQSDPGTSVLGYQ 694
Query: 2989 VSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGS--DFMWGSSVTYACLEGYQLSL 3046
+ + N T C P IPNG S + + G+ VTY C GYQ+
Sbjct: 695 QGFVIHFFEVPRNDT--------CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVG 746
Query: 3047 PAVFTCEGNGSWTGELPQCFPV-FCGDPGVPSRGRR--EDRGFSYRSSVSFSCHPPLVLV 3103
+V C+ + +W+ +LP C V C DPG RR F ++V + C VL+
Sbjct: 747 SSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLM 806
Query: 3104 GSPRRFCQ----SDGTWSGTQPSCIDPTLTTCADPGVPQFGIQN-NSQGYQVGSTVLFRC 3158
GS C WS P C+ L C P+ G ++ Q + G+T+ F C
Sbjct: 807 GSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSC 866
Query: 3159 QKGYLLQGSTTRTCLPN--LTWSGTPPDC 3185
GY+L+G + C+P WS PP C
Sbjct: 867 APGYVLKGQASIKCVPGHPSHWSDPPPIC 895
Score = 81.6 bits (200), Expect = 1e-14
Identities = 59/190 (31%), Positives = 88/190 (46%), Gaps = 16/190 (8%)
Query: 3092 VSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQN-NSQGYQV 3150
V++ C+P +VGS CQ D TWS PSC +T+C DPG + + +S + V
Sbjct: 734 VTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC--QRVTSCHDPGDVEHSRRLISSPKFPV 791
Query: 3151 GSTVLFRCQKGYLLQGSTTRTC----LPNLTWSGTPPDCVPHH---CRQPETPTH-ANVG 3202
G+TV + C +G++L GS+ TC + WS P C+ C P + A
Sbjct: 792 GATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSP 851
Query: 3203 ALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGS-WTGKPPICLEVRPSG----RPINT 3257
L G T+ +SC G+ LKG + + S W+ PPIC G R ++
Sbjct: 852 EKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLDGFYNSRSLDV 911
Query: 3258 AREPPLTQAL 3267
A+ P + L
Sbjct: 912 AKAPAASSTL 921
Score = 49.7 bits (117), Expect = 5e-05
Identities = 55/210 (26%), Positives = 87/210 (41%), Gaps = 40/210 (19%)
Query: 1557 SCFDPGSIKNGTRVGSDLK--LGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPV 1614
SC DPG +++ R+ S K +G++V Y C G+ + G+S L+C G P W++ P
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 1615 C----TAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALND 1670
C PC G +G SP Q + +G ++F P YV+ GQ +
Sbjct: 830 CLLEQLKPCHGLSAPENG-ARSPE-KQLHPAG-ATIHFSCAP-GYVLKGQAS-------- 877
Query: 1671 VVEVHDGHSQHSR------LLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPA------- 1717
++ GH H +SL G + SL +A + A +A A
Sbjct: 878 -IKCVPGHPSHWSDPPPICRAASLDGFYNSRSLDVAKAPAASSTLDAAHIAAAIFLPLVA 936
Query: 1718 -----RGFHFVYQAVPRTSATQCSSVPEPR 1742
G +F + + S+ Q +P PR
Sbjct: 937 MVLLVGGVYFYFSRLQGKSSLQ---LPRPR 963
Score = 42.4 bits (98), Expect = 0.008
Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 4/78 (5%)
Query: 138 TCGNPGRLPNGIQQGST--FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
+C +PG + + + S+ F +G V+Y C+ GF L G ++LTCH S W P
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 196 CRADD--ACGGTLRGQSG 211
C + C G ++G
Sbjct: 830 CLLEQLKPCHGLSAPENG 847
Score = 38.5 bits (88), Expect = 0.12
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 6/62 (9%)
Query: 520 SCGDPGIPAYGRR--EGSRFHHGDTLKFECQPAFELVGQKAITCQKNN----QWSAKKPG 573
SC DPG + RR +F G T+++ C F L+G +TC +WS + P
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 574 CV 575
C+
Sbjct: 830 CL 831
Score = 38.1 bits (87), Expect = 0.15
Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 4/66 (6%)
Query: 343 CPDPGIPERGKRLGSD--FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVC 400
C PE G R G+++ F+C GY L+G I C V + WSD P+C
Sbjct: 838 CHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKC--VPGHPSHWSDPPPIC 895
Query: 401 RARMCD 406
RA D
Sbjct: 896 RAASLD 901
>gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens]
Length = 994
Score = 271 bits (693), Expect = 8e-72
Identities = 218/761 (28%), Positives = 328/761 (43%), Gaps = 82/761 (10%)
Query: 1049 IRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGT 1108
+ +G G+ T+T S G E T T + +P P C + +G +G+
Sbjct: 200 VSQGAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGP-----CSWNFSGPEGS 254
Query: 1109 LLSP-NFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGVF 1167
L SP + + +C + I PG G+++K + L EG+ + V +G L
Sbjct: 255 LDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV-EGLGGPDPLPLAN 313
Query: 1168 SHSEMMGVTLNSTSSSLWLDFITDAENTSKG-FELHFSSFELIKCEDPGTPKFGYKVHDE 1226
+ G + S + L F + G F H+ ++ L+ C P P +G
Sbjct: 314 QSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAY-LLSCHFPRRPAYGDVTVTS 372
Query: 1227 GHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSP 1286
H G S F C GY L+G+ L CL+ + WD P C+A CGG +R +G+++SP
Sbjct: 373 LH-PGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSP 431
Query: 1287 GYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGP-VESGVLLKELSGP 1345
G+P Y +NL C W +EA G + LHF E D L I +G VE+ +
Sbjct: 432 GFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVE 491
Query: 1346 ALP-KDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQ-NGSRSGDSWEA 1403
LP + L S+ ++ STD + G A+++ C +P + N S S ++
Sbjct: 492 YLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPV 551
Query: 1404 GDSTVFQCDPGYAL-QGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYP 1462
G + F CDPGY L QGS I CV + W + P C A C G++T +GV+LSPN+P
Sbjct: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDP-QWNETEPACRAVCSGEITDSAGVVLSPNWP 610
Query: 1463 EPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPG 1522
EPY G++C W V V D I L + + PG D L YDG D + ++G + G +
Sbjct: 611 EPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHF 669
Query: 1523 RIESSSNSLFLAFRSDASVS----NAGFVIDYTENPR-ESCFDPGSIKNGTRVGSDLKL- 1576
++ +S + + F+SD S GFVI + E PR ++C + I NG + S +L
Sbjct: 670 KLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELV 729
Query: 1577 -GSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVC--TAPC--GGQYVGSDGVVL 1631
G+ VTY C+ GY+V G+S L C W+ P C C G S ++
Sbjct: 730 HGTVVTYQCYPGYQVVGSSVLMC----QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLIS 785
Query: 1632 SPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGS 1691
SP +P T IC + +V+ G + ++ HD +
Sbjct: 786 SPKFPVGATVQYIC------DQGFVLMG---------SSILTCHDRQA---------GSP 821
Query: 1692 HTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSDF 1751
+ P Q L P G + P A P
Sbjct: 822 KWSDRAPKCLLEQ---------LKPCHGL-----SAPENGARSPEKQLHP---------- 857
Query: 1752 SVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC 1792
GA + F C GY L+G I+C VPG + W+ P C
Sbjct: 858 -AGATIHFSCAPGYVLKGQASIKC--VPGHPSHWSDPPPIC 895
Score = 207 bits (526), Expect = 2e-52
Identities = 197/726 (27%), Positives = 300/726 (41%), Gaps = 106/726 (14%)
Query: 578 CFFNFTSPSGVVLSP---NYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVI 634
C +NF+ P G + SP + P D G L C + I P + + +I +
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVG--LDCFFYISVYPGYGVEIKVQNIS---------L 292
Query: 635 KDGATAEAPVLGTFSGNQLPSS----------ITSSGHVARLEFQT-DHSTGKRGFNITF 683
++G T LG + LP + I S H A L FQ+ G F+ +
Sbjct: 293 REGETVTVEGLG--GPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHY 350
Query: 684 TTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNS 743
+ + C P P G SL G S F C G+ +G+ +TC L W+S
Sbjct: 351 QAYLLS-CHFPRRPAYGDVTVTSLHPGGSARFHCATGYQ-LKGARHLTC-LNATQPFWDS 407
Query: 744 AVLRCEAPCGGHL-TSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN 802
C A CGG + + +G I+SPG+PG Y + L+C W++EA G + + F++ +
Sbjct: 408 KEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAED 467
Query: 803 YDTLEVRDGRTYSAPLI-GVYHGTQVP-QFLISTSNYLYLLFSTDKSHSDIGFQLRYETI 860
D L +R+G AP + Y +P + L+S+ + ++ STD S + G LRYE
Sbjct: 468 DDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAF 527
Query: 861 TLQSDHCLDPGIPVNGQRHGNDFY-VGALVTFSCDSGYTLSDGEPL-EC-EPNF-QWSRA 916
Q HC +P + Y VG V FSCD GYTL G + EC +P+ QW+
Sbjct: 528 --QQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNET 585
Query: 917 LPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHD 976
P+C A+C G I S+G +LSP +P+ Y +C W + K + + G D
Sbjct: 586 EPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-D 644
Query: 977 YLLITENGSFT-QPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMS----YEGFNITF 1031
L + T + L Q +G R + + ++F SD S +GF I F
Sbjct: 645 VLTFYDGDDLTARVLGQYSGPRSHFKLFTSM---ADVTIQFQSDPGTSVLGYQQGFVIHF 701
Query: 1032 SEYDL-EPCEE-PEVP-AYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWS 1088
E + C E PE+P + + G +T+ C+PGY++ G++ + C WS
Sbjct: 702 FEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWS 759
Query: 1089 SPLPRC--VAECGN--SVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFE 1144
LP C V C + V ++ + SP FPV + C + F
Sbjct: 760 EDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYIC---------------DQGFV 804
Query: 1145 LSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFS 1204
L +L +D S W D
Sbjct: 805 LMGSSILTCHD----------------------RQAGSPKWSDRAPKC-----------L 831
Query: 1205 SFELIKCEDPGTPKFGYKVHDEG-HFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRP 1263
+L C P+ G + ++ H AG+++ FSC PGY L+G + C+ G W P
Sbjct: 832 LEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDP 891
Query: 1264 LPTCVA 1269
P C A
Sbjct: 892 PPICRA 897
Score = 201 bits (511), Expect = 1e-50
Identities = 155/555 (27%), Positives = 244/555 (43%), Gaps = 26/555 (4%)
Query: 405 CDAHLRGPSGIITSP-NFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVG 463
C + GP G + SP + D C + I+ P +++ + L G G
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVY-PGYGVEIKVQNISLREGETVTVEG 302
Query: 464 DGGQDG-DQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCG 522
GG D ++L G +I S HQ L FQ+ + G + + SC
Sbjct: 303 LGGPDPLPLANQSFLLRG----QVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCH 358
Query: 523 DPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQ--WSAKKPGCVFSCFF 580
P PAYG + H G + +F C ++L G + +TC Q W +K+P C+ +C
Sbjct: 359 FPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGG 418
Query: 581 NF-TSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGAT 639
+ +G ++SP +P +Y N+L C WL+ A R+HL F + + D L+I++G
Sbjct: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDN 478
Query: 640 AEA-PVLGTFSGNQLP-SSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVP 697
EA PV ++ LP + SSG +E TD S G + + F+ C +P V
Sbjct: 479 VEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVK 538
Query: 698 V-NGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHL 756
N + +G+++ F CD G+ QGS I CV WN C A C G +
Sbjct: 539 YGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV-DPHDPQWNETEPACRAVCSGEI 597
Query: 757 TSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSA 816
T +G +LSP WP Y C W + + I + + D L DG +A
Sbjct: 598 TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTA 656
Query: 817 PLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQ---SDHCLD-PGI 872
++G Y G + L ++ + + F +D S +G+Q + + +D C + P I
Sbjct: 657 RVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEI 716
Query: 873 PVNGQRHGN--DFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCG----G 926
P NG + + + G +VT+ C GY + L C+ + WS LPSC+ + G
Sbjct: 717 P-NGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPG 775
Query: 927 FIQGSSGTILSPGFP 941
++ S I SP FP
Sbjct: 776 DVEHSRRLISSPKFP 790
Score = 194 bits (494), Expect = 1e-48
Identities = 170/605 (28%), Positives = 253/605 (41%), Gaps = 85/605 (14%)
Query: 1384 SCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIA 1443
SC+ P P G + S G S F C GY L+G+ ++C+ F W P CIA
Sbjct: 356 SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPF-WDSKEPVCIA 414
Query: 1444 PCGGDL-TGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIY 1502
CGG + +G I+SP +P Y C W + + L F +L D L I
Sbjct: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIR 474
Query: 1503 DGRD-SLSPLIGSFYGSQLPGR-IESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFD 1560
+G + P+ S+ LP + SS F+ +D+S + AG + Y + C++
Sbjct: 475 NGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYE 534
Query: 1561 PGSIKNGTRVGSD--LKLGSSVTYYCHGGYEVE-GTSTLSCILGPDGKPVWNNPRPVCTA 1617
P +K G S +G++V + C GY +E G+ + C+ D P WN P C A
Sbjct: 535 P-FVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHD--PQWNETEPACRA 591
Query: 1618 PCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDG 1677
C G+ S GVVLSPN+P+ Y GQ C++ V V +D + DV+ +DG
Sbjct: 592 VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDG 651
Query: 1678 HSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSA----KGLAPARGFHFVYQAVPRTSAT 1733
+R+L SG + L + V I+F + L +GF + VPR
Sbjct: 652 DDLTARVLGQYSGPRSHFKL-FTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDT- 709
Query: 1734 QCSSVPEPRYGKRLGS--DFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVS--- 1788
C +PE G + S + G +V ++C GY + GS + C QW+++
Sbjct: 710 -CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMC--------QWDLTWSE 760
Query: 1789 -APTC--VVPC--GGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVT 1843
P+C V C G++ R I SP FP G +Q +
Sbjct: 761 DLPSCQRVTSCHDPGDVEHSRRLISSPKFP------------------VGATVQYI---- 798
Query: 1844 EQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 1903
D ++GS ++L Q +SD A LE
Sbjct: 799 ------------CDQGFVLMGS-------SILTCHDRQAGSPKWSD---RAPKCLLEQ-- 834
Query: 1904 VGLSSCPEPAVPSNGVKTGERYL--VNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPP 1961
L C + P NG ++ E+ L + F C PGY L+G A I C+PG W+ PP
Sbjct: 835 --LKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPP 892
Query: 1962 PLCIA 1966
P+C A
Sbjct: 893 PICRA 897
Score = 190 bits (482), Expect = 2e-47
Identities = 175/637 (27%), Positives = 257/637 (40%), Gaps = 75/637 (11%)
Query: 1587 GYEVEGTSTLSCILGPDGKPVWNNPRPVCT-------APCGGQYVGSDGVVLSPNYPQNY 1639
G ++GT T S G D + T PC + G +G + SP +
Sbjct: 205 GIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGPCSWNFSGPEGSLDSPTDLSSP 264
Query: 1640 TS-GQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLP 1698
T G C ++++V Y V + + V V L++ S G+ +
Sbjct: 265 TDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQSFLLRGQVIR 324
Query: 1699 LATSNQVLIKFSAKGLAPARG---FHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGA 1755
T +Q ++F + L P G FHF YQA C P YG + G
Sbjct: 325 SPT-HQAALRFQS--LPPPAGPGTFHFHYQAY----LLSCHFPRRPAYGDVTVTSLHPGG 377
Query: 1756 IVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERR-GTILSPGFPE 1814
RF C +GY L+G+ + CL W+ P C+ CGG + G I+SPGFP
Sbjct: 378 SARFHCATGYQLKGARHLTCLNATQPF--WDSKEPVCIAACGGVIRNATTGRIVSPGFPG 435
Query: 1815 PYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVT--MLGSFSGTTVP 1872
Y N+L C W + PEG + + ++ D L + +G DN + S+ +P
Sbjct: 436 NYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNG-DNVEAPPVYDSYEVEYLP 494
Query: 1873 AL-LNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVP-SNGVKTGERYLVNDV 1930
L S+ ++ +D S +AAG L Y+ C EP V N + Y V
Sbjct: 495 IEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTT 554
Query: 1931 VSFQCEPGYAL-QGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVILSPGFPGNYP 1989
V F C+PGY L QG I C+ +WN P C A C G + + GV+LSP +P Y
Sbjct: 555 VEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYG 614
Query: 1990 SNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELPSSLLS 2049
DC W + + + P D + +G T+R++G++SG L +
Sbjct: 615 RGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHFKLFT 673
Query: 2050 TSHETTVYFHSDHSQNRPGFK-LEYQDLTYSHQISSFLRGFDLSELERTNSTPPVAASYV 2108
+ + T+ F SD PG L YQ H E+ R ++ P
Sbjct: 674 SMADVTIQFQSD-----PGTSVLGYQQGFVIH----------FFEVPRNDTCP------- 711
Query: 2109 WDLDPGCEAYELQECPD--PEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHG 2166
EL E P+ P +V G VT++C PGYQ+ G VL CQ
Sbjct: 712 ----------ELPEIPNGWKSPSQPELVHGT------VVTYQCYPGYQVVGSSVLMCQ-- 753
Query: 2167 TNRNWDHPLPKCE--VPC--GGNITSSNGTVYSPGFP 2199
+ W LP C+ C G++ S + SP FP
Sbjct: 754 WDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 790
Score = 180 bits (456), Expect = 3e-44
Identities = 153/564 (27%), Positives = 247/564 (43%), Gaps = 38/564 (6%)
Query: 1444 PCGGDLTGPSGVILSP-NYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIY 1502
PC + +GP G + SP + P G +C + ++V P Y + + +L G
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVT--V 300
Query: 1503 DGRDSLSPLIGSFYGSQLPGR-IESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDP 1561
+G PL + L G+ I S ++ L F+S + G + + SC P
Sbjct: 301 EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFP 360
Query: 1562 GSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGG 1621
G + L G S ++C GY+++G L+C+ +P W++ PVC A CGG
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNAT--QPFWDSKEPVCIAACGG 418
Query: 1622 QYVGSD-GVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDV-VEVHDGHS 1679
+ G ++SP +P NY++ C + + P+ + F A +D + + +G +
Sbjct: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDN 478
Query: 1680 QHSRLLSSLSGSHTGESLP----LATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQC 1735
+ + S+ E LP L++ ++ S A G Y+A + +
Sbjct: 479 VEA---PPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYE- 534
Query: 1736 SSVPEPRYGKRLGSD--FSVGAIVRFECNSGYAL-QGSPEIECLPVPGALAQWNVSAPTC 1792
P +YG S + VG V F C+ GY L QGS IEC+ QWN + P C
Sbjct: 535 ---PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDP--QWNETEPAC 589
Query: 1793 VVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEV 1852
C G +T+ G +LSP +PEPY +C+W + V E I + + + D L
Sbjct: 590 RAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLD-IRVLRIGPGDVLTF 648
Query: 1853 FDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLE-----YKTVGLS 1907
+DG D T +LG +SG L ++ + + F SD S G+ ++
Sbjct: 649 YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRND 708
Query: 1908 SCPE-PAVPSNGVKTGERYLVN-DVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLC- 1964
+CPE P +P+ + LV+ VV++QC PGY + G + + C W+ P C
Sbjct: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLT--WSEDLPSCQ 766
Query: 1965 -IAQC--GGTVEEMEGVILSPGFP 1985
+ C G VE +I SP FP
Sbjct: 767 RVTSCHDPGDVEHSRRLISSPKFP 790
Score = 176 bits (445), Expect = 5e-43
Identities = 162/583 (27%), Positives = 240/583 (41%), Gaps = 37/583 (6%)
Query: 2096 RTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQL 2155
R S PP A + +AY L C P A G V + G S F C GYQL
Sbjct: 333 RFQSLPPPAGPGTFHFH--YQAY-LLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQL 389
Query: 2156 TGHPVLTCQHGTNRNWDHPLPKCEVPCGGNI-TSSNGTVYSPGFPSPYSSSQDCVWLITV 2214
G LTC + T WD P C CGG I ++ G + SPGFP YS++ C WL+
Sbjct: 390 KGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEA 449
Query: 2215 PIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRL--GVFTRSMAKKTVQSSSNQVLLKF 2272
P G + L+ + D + I +G AP + + + + SS ++
Sbjct: 450 PEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVEL 509
Query: 2273 HRD---AATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTL- 2328
D AA G A+ + A+ C P + + + +G V + C PG+TL
Sbjct: 510 STDSSGAAAG--MALRYEAFQQGHCYEP-FVKYGNFSSSTPTYPVGTTVEFSCDPGYTLE 566
Query: 2329 VGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVR 2388
G+ I+ C Q+ P C C +TDS GV+LS ++P Y + Q C W V
Sbjct: 567 QGSIIIECVDPHDPQWNETEPACRAVCSGE--ITDSAGVVLSPNWPEPYGRGQDCIWGVH 624
Query: 2389 VEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRW 2448
VE D I L + L D +DG + +L SG S + TS ++ V +++
Sbjct: 625 VEEDKRIMLDIR-VLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMAD-VTIQF 682
Query: 2449 SSDHAYN----RKGFKIRY-----SAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGY 2499
SD + ++GF I + + LP P Q G + + C GY
Sbjct: 683 QSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGY 742
Query: 2500 RLVGHSMAICTRHPQGYHLWSEAIPLCQAL-SCGLPEAPKNG--MVFGKEYTVGTKAMYS 2556
++VG S+ +C Q WSE +P CQ + SC P ++ ++ ++ VG Y
Sbjct: 743 QVVGSSVLMC----QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYI 798
Query: 2557 CSEGYHLQAGAEATAECLDTG--LWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQY 2614
C +G+ L + T G WS+R P+C+ +S R + +
Sbjct: 799 CDQGFVLMGSSILTCHDRQAGSPKWSDR--APKCLLEQLKPCHGLSAPENGARSPEKQLH 856
Query: 2615 QFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIIS 2657
A + C PGY GQ I+C D P CR S
Sbjct: 857 PAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAAS 899
Score = 164 bits (416), Expect = 1e-39
Identities = 123/427 (28%), Positives = 189/427 (44%), Gaps = 25/427 (5%)
Query: 343 CPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRA 402
C P P G + G S +F C GY L+G++ +TC+ + F W PVC A
Sbjct: 357 CHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPF--WDSKEPVCIA 414
Query: 403 RMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTV 462
+G I SP FP Y NN C W++ A + + L FE+ L D L +
Sbjct: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQR-LHLHFEKVSLAEDDDRLII 473
Query: 463 GDGGQ-DGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSC 521
+G + Y + + L+ S H ++ TD SG++ G YE +QG C
Sbjct: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKH-FFVELSTDSSGAAAGMALRYEAFQQGHC 532
Query: 522 GDPGIPAYGRREGSR--FHHGDTLKFECQPAFELV-GQKAITC--QKNNQWSAKKPGCVF 576
+P + YG S + G T++F C P + L G I C + QW+ +P C
Sbjct: 533 YEPFVK-YGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRA 591
Query: 577 SCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKD 636
C T +GVVLSPN+PE YG C+W + + RI L + + P D L D
Sbjct: 592 VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYD 650
Query: 637 GATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTF-----RHNEC 691
G A VLG +SG + + +S ++FQ+D T G+ F R++ C
Sbjct: 651 GDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTC 710
Query: 692 PD-PGVPVNGKRFGDSLQL--GSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRC 748
P+ P +P NG + +L G+ +++ C G+ GS + C + + W+ + C
Sbjct: 711 PELPEIP-NGWKSPSQPELVHGTVVTYQCYPGY-QVVGSSVLMC---QWDLTWSEDLPSC 765
Query: 749 EAPCGGH 755
+ H
Sbjct: 766 QRVTSCH 772
Score = 139 bits (351), Expect = 4e-32
Identities = 167/688 (24%), Positives = 268/688 (38%), Gaps = 66/688 (9%)
Query: 2181 PCGGNITSSNGTVYSP-GFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITI- 2238
PC N + G++ SP SP DC + I+V G+GV + + + G+ +T+
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLR-EGETVTVE 301
Query: 2239 -WDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHR--DAATGGIFAIAFSAYPLTKCP 2295
GP L + + + ++S ++Q L+F A G F + AY L C
Sbjct: 302 GLGGPDPLP--LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAY-LLSCH 358
Query: 2296 PPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHC 2355
P +V + + G R+ C G+ L G LTC T ++ P+C C
Sbjct: 359 FPRRPAYGDVTVTS--LHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAAC 416
Query: 2356 PTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFD 2415
+ +TG I+S +PG+Y TC WL+ + L E + D I +
Sbjct: 417 -GGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
Query: 2416 GPSGQS-PLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA---PYCSLP 2471
G + ++ P+ + Y + SS ++ S+D + G +RY A +C P
Sbjct: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
Query: 2472 RAPLHGFILGQTSTQP-GGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALS 2530
+G T T P G ++ F C+ GY L S+ I P W+E P C+A+
Sbjct: 536 FVK-YGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQ-WNETEPACRAV- 592
Query: 2531 CGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCV- 2589
C G+V + C G H++ E LD + + P V
Sbjct: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVE---EDKRIMLDIRV---LRIGPGDVL 646
Query: 2590 ------PVTCPDVSSISVEHGRWRL---IFETQYQFQAQLMLICDPGYYYTGQRVIRCQA 2640
+T + S ++L + + QFQ+ DPG G +
Sbjct: 647 TFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQS------DPGTSVLGYQ------ 694
Query: 2641 NGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLS--VYGATAIFSCNSGYTLVGSRVREC 2698
+ + R +C ELP PNG + + V+G + C GY +VGS V C
Sbjct: 695 --QGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMC 752
Query: 2699 MANGLWSGSEVRC-LAGHCGTPEPIVNGH--INGENYSYRGSVVYQCNAGFRLIGMSVRI 2755
+ WS C C P + + I+ + +V Y C+ GF L+G S+
Sbjct: 753 QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILT 812
Query: 2756 CQQ----DHHWSGKTPFCVLVS---CGHPGSPPHSQMSGDS--YTVGAVVRYSCIGKRTL 2806
C WS + P C+L C +P + S + + GA + +SC L
Sbjct: 813 CHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVL 872
Query: 2807 VGNSTRMC--GLDGHWTGSLPHCSGTSV 2832
G ++ C G HW+ P C S+
Sbjct: 873 KGQASIKCVPGHPSHWSDPPPICRAASL 900
Score = 138 bits (348), Expect = 8e-32
Identities = 150/573 (26%), Positives = 238/573 (41%), Gaps = 65/573 (11%)
Query: 26 CTFQLHGPNGTVESPGFPYGYPNYA-NCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFD 84
C++ GP G+++SP + +C + I+ + +++ Q+ +L E V
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGL 303
Query: 85 GPPQPENLRTRLTGFQLPATIVSAAT-TLSLRLISDYAVSAQG-FHATYEVLPSHTCGNP 142
G P P L + F L ++ + T +LR S + G FH Y+ +C P
Sbjct: 304 GGPDPLPLANQ--SFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFP 360
Query: 143 GRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDAC 202
R G ++ + G R+ C G+ L+G LTC ++ WD P C A AC
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQ--PFWDSKEPVCIA--AC 416
Query: 203 GGTLRGQS-GIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGT 261
GG +R + G I SP FP Y NN C W + A G + L F L + D L +
Sbjct: 417 GGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIR-- 474
Query: 262 EGSSLWFTGASLPAPVISSK---NWLRLH-FTSDGNHRQRGFSAQYQVKKQIELKSRGVK 317
G ++ AP + +L + S G H V+
Sbjct: 475 -------NGDNVEAPPVYDSYEVEYLPIEGLLSSGKH-------------------FFVE 508
Query: 318 LMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGS--DFRLGSSVQFTCNEGYDL 375
L + L QGH C +P + + G S + +G++V+F+C+ GY L
Sbjct: 509 LSTDSSGAAAGMALRYEAFQQGH--CYEPFV-KYGNFSSSTPTYPVGTTVEFSCDPGYTL 565
Query: 376 -QGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWI 434
QGS I C+ D W++ P CRA +C + +G++ SPN+P Y C+W
Sbjct: 566 EQGSIIIECVDPHD--PQWNETEPACRA-VCSGEITDSAGVVLSPNWPEPYGRGQDCIWG 622
Query: 435 ITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQM 494
+ + K I L + G D LT DG D VL +G + ++ +
Sbjct: 623 V-HVEEDKRIMLDIRVLRIGPG-DVLTFYDG--DDLTARVLGQYSGPRSHFKLFTSMADV 678
Query: 495 WLLFQTDGSGSSLGFKAS-----YEEIEQGSCGD-PGIP-AYGRREGSRFHHGDTLKFEC 547
+ FQ+D S LG++ +E +C + P IP + HG + ++C
Sbjct: 679 TIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQC 738
Query: 548 QPAFELVGQKAITCQKNNQWSAKKPGC--VFSC 578
P +++VG + CQ + WS P C V SC
Sbjct: 739 YPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSC 771
Score = 112 bits (279), Expect = 8e-24
Identities = 104/414 (25%), Positives = 167/414 (40%), Gaps = 57/414 (13%)
Query: 35 GTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG-----PPQP 89
G + SPGFP Y N C W + A E R+ L F+ +L ED D L + +G PP
Sbjct: 426 GRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVY 485
Query: 90 ENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNP-GRLPNG 148
++ + ++S+ + L +D + +A G YE C P + N
Sbjct: 486 DSYEVEYLPIE---GLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNF 542
Query: 149 IQQGSTFNLGDKVRYSCNLGFFLE-GHAVLTCHAGSENSATWDFPLPSCRADDACGGTLR 207
T+ +G V +SC+ G+ LE G ++ C + W+ P+CRA C G +
Sbjct: 543 SSSTPTYPVGTTVEFSCDPGYTLEQGSIIIEC--VDPHDPQWNETEPACRA--VCSGEIT 598
Query: 208 GQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG-----YDFLEVTGTE 262
+G++ SP++P Y DC W + E I L ++ G YD ++T
Sbjct: 599 DSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARV 658
Query: 263 GSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVKLMPSK 322
++G + +S + + F SD G+ + + ++ +P
Sbjct: 659 LGQ--YSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEI 716
Query: 323 DNSQKT---------SVLTQ--------VGVS-----------------QGHNMCPDPGI 348
N K+ +V+T VG S Q C DPG
Sbjct: 717 PNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGD 776
Query: 349 PERGKRLGSD--FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVC 400
E +RL S F +G++VQ+ C++G+ L GS +TC WSD P C
Sbjct: 777 VEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKC 830
Score = 100 bits (248), Expect = 3e-20
Identities = 137/569 (24%), Positives = 205/569 (36%), Gaps = 65/569 (11%)
Query: 2655 IISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECM--ANGLWSGSEVRCL 2712
++SC P G T G +A F C +GY L G+R C+ W E C+
Sbjct: 354 LLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCI 413
Query: 2713 AGHCGTPEPIVNGHINGENYSYRGSVVYQCN--------AGFRLIGMSVRICQQDHHWSG 2764
A G G I + S C+ L V + + D
Sbjct: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDR--- 470
Query: 2765 KTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCI--GKRTLVGNSTRMCGLDGHWTG 2822
++ + + +PP DSY V + + GK V ST G G
Sbjct: 471 ----LIIRNGDNVEAPPVY----DSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAA---G 519
Query: 2823 SLPHCSGTSVGVCGDPGIPAHGIRLGDSFDP-GTVMRFSCEAGHVLRGSS---ERTCQAN 2878
G C +P + P GT + FSC+ G+ L S E +
Sbjct: 520 MALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHD 579
Query: 2879 GSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATG---------- 2928
W+ ++P C + G +A VV S +C G +
Sbjct: 580 PQWNETEPACRAVCSGE--ITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRV 637
Query: 2929 LLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHR 2988
L V + G D V+ G P + +L + T+ +Q PG + ++
Sbjct: 638 LRIGPGDVLTFYDGDDLTARVL--GQYSGPRSHFKLFTSMA-DVTIQFQSDPGTSVLGYQ 694
Query: 2989 VSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGS--DFMWGSSVTYACLEGYQLSL 3046
+ + N T C P IPNG S + + G+ VTY C GYQ+
Sbjct: 695 QGFVIHFFEVPRNDT--------CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVG 746
Query: 3047 PAVFTCEGNGSWTGELPQCFPV-FCGDPGVPSRGRR--EDRGFSYRSSVSFSCHPPLVLV 3103
+V C+ + +W+ +LP C V C DPG RR F ++V + C VL+
Sbjct: 747 SSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLM 806
Query: 3104 GSPRRFCQ----SDGTWSGTQPSCIDPTLTTCADPGVPQFGIQN-NSQGYQVGSTVLFRC 3158
GS C WS P C+ L C P+ G ++ Q + G+T+ F C
Sbjct: 807 GSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSC 866
Query: 3159 QKGYLLQGSTTRTCLPN--LTWSGTPPDC 3185
GY+L+G + C+P WS PP C
Sbjct: 867 APGYVLKGQASIKCVPGHPSHWSDPPPIC 895
Score = 81.6 bits (200), Expect = 1e-14
Identities = 59/190 (31%), Positives = 88/190 (46%), Gaps = 16/190 (8%)
Query: 3092 VSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQN-NSQGYQV 3150
V++ C+P +VGS CQ D TWS PSC +T+C DPG + + +S + V
Sbjct: 734 VTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC--QRVTSCHDPGDVEHSRRLISSPKFPV 791
Query: 3151 GSTVLFRCQKGYLLQGSTTRTC----LPNLTWSGTPPDCVPHH---CRQPETPTH-ANVG 3202
G+TV + C +G++L GS+ TC + WS P C+ C P + A
Sbjct: 792 GATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSP 851
Query: 3203 ALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGS-WTGKPPICLEVRPSG----RPINT 3257
L G T+ +SC G+ LKG + + S W+ PPIC G R ++
Sbjct: 852 EKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLDGFYNSRSLDV 911
Query: 3258 AREPPLTQAL 3267
A+ P + L
Sbjct: 912 AKAPAASSTL 921
Score = 49.7 bits (117), Expect = 5e-05
Identities = 55/210 (26%), Positives = 87/210 (41%), Gaps = 40/210 (19%)
Query: 1557 SCFDPGSIKNGTRVGSDLK--LGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPV 1614
SC DPG +++ R+ S K +G++V Y C G+ + G+S L+C G P W++ P
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 1615 C----TAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALND 1670
C PC G +G SP Q + +G ++F P YV+ GQ +
Sbjct: 830 CLLEQLKPCHGLSAPENG-ARSPE-KQLHPAG-ATIHFSCAP-GYVLKGQAS-------- 877
Query: 1671 VVEVHDGHSQHSR------LLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPA------- 1717
++ GH H +SL G + SL +A + A +A A
Sbjct: 878 -IKCVPGHPSHWSDPPPICRAASLDGFYNSRSLDVAKAPAASSTLDAAHIAAAIFLPLVA 936
Query: 1718 -----RGFHFVYQAVPRTSATQCSSVPEPR 1742
G +F + + S+ Q +P PR
Sbjct: 937 MVLLVGGVYFYFSRLQGKSSLQ---LPRPR 963
Score = 42.4 bits (98), Expect = 0.008
Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 4/78 (5%)
Query: 138 TCGNPGRLPNGIQQGST--FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
+C +PG + + + S+ F +G V+Y C+ GF L G ++LTCH S W P
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 196 CRADD--ACGGTLRGQSG 211
C + C G ++G
Sbjct: 830 CLLEQLKPCHGLSAPENG 847
Score = 38.5 bits (88), Expect = 0.12
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 6/62 (9%)
Query: 520 SCGDPGIPAYGRR--EGSRFHHGDTLKFECQPAFELVGQKAITCQKNN----QWSAKKPG 573
SC DPG + RR +F G T+++ C F L+G +TC +WS + P
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 574 CV 575
C+
Sbjct: 830 CL 831
Score = 38.1 bits (87), Expect = 0.15
Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 4/66 (6%)
Query: 343 CPDPGIPERGKRLGSD--FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVC 400
C PE G R G+++ F+C GY L+G I C V + WSD P+C
Sbjct: 838 CHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKC--VPGHPSHWSDPPPIC 895
Query: 401 RARMCD 406
RA D
Sbjct: 896 RAASLD 901
>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
isoform 2 [Homo sapiens]
Length = 1033
Score = 265 bits (678), Expect = 5e-70
Identities = 241/911 (26%), Positives = 343/911 (37%), Gaps = 147/911 (16%)
Query: 2468 CSLPRAPLHGFI-LGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLC 2526
C P L+G I T G I + C+ +RL+G +C + W + P C
Sbjct: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
Query: 2527 QAL----SCGLPEAPKNGMVFGKE-YTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSN 2581
+ SC P P + G Y G ++C + + C +W
Sbjct: 83 EYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVW--CQANNMWGP 140
Query: 2582 RNVPPQCV---PVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRC 2638
+P CV P+ CP + I H + C+ GY G+++I C
Sbjct: 141 TRLPT-CVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYS--CESGYLLVGEKIINC 197
Query: 2639 QANGKWSLGDSTPTCRIISCGELPIPPNGH-RIGTLSVYGATAIFSCNSGYTLVGSRVRE 2697
++GKWS PTC C L PNG + + G TA F C+ GY L G
Sbjct: 198 LSSGKWSA--VPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 2698 CMANG---LWSGSEVRCLAGHCGTPEPIVNG-HINGE--NYSYRGSVVYQCN------AG 2745
C+ G W+ V C C +P PI+NG HI N SY V Y C+
Sbjct: 256 CVIAGQGVAWTKMPV-CEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
Query: 2746 FRLIGMSVRICQQDHH----WSGKTPFCVL----VSCGHPGSPPHSQMSG--DSYTVGAV 2795
F LIG S C D WSG P C L V C HP +SG D YT
Sbjct: 315 FILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDT 374
Query: 2796 VRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSG---TSVGVCGDPGIPAHGIRLGDSFD 2852
V ++C+ TL G+ C G W S P C + H +R FD
Sbjct: 375 VIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVR----FD 430
Query: 2853 PGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPG----TPSNARVVFSD 2908
PGT +++SC G+VL G C + G W+ P+C V +C G T + V D
Sbjct: 431 PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPD 490
Query: 2909 GLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGN-- 2966
+ C EGY +G + + C W C I C P + NG G+
Sbjct: 491 -------VNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSL 543
Query: 2967 -DFRYNKTVTYQCVP----GYMMESHRVSVLSCTKD----RTWNGTKPVCK----ALMCK 3013
DF Y TVTY C P G S + CT + TW+G P+CK A+ C
Sbjct: 544 EDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCS 603
Query: 3014 PPPLIPNGKVVGSD--FMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCG 3071
+ K+ G + + + +VT+ C G+ L + C+ + +W E+P C C
Sbjct: 604 HVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQ 663
Query: 3072 D-----PGVPSRGRREDRGFSYRSSVSFS--------------------------CHPPL 3100
+P+ R E S + + CHPP
Sbjct: 664 HVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPP 723
Query: 3101 VLV-----------------------------GSPRRFCQSD----GTWSGTQPSCI-DP 3126
V+V G + C+SD G+WSG P C+ P
Sbjct: 724 VIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSP 783
Query: 3127 TLTTCADPGVPQ-FGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDC 3185
+T C +P V + + Y V C G+++ GS C + TW P C
Sbjct: 784 PVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTC 843
Query: 3186 VPHHC----RQPETPTHANVGA-LDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTG 3240
+ P+TP + G + S G +++YSC +G+ L G C +G+W+
Sbjct: 844 IKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLV-GEALLLCTHEGTWSQ 902
Query: 3241 KPPICLEVRPS 3251
P C EV S
Sbjct: 903 PAPHCKEVNCS 913
Score = 255 bits (651), Expect = 6e-67
Identities = 218/826 (26%), Positives = 326/826 (39%), Gaps = 93/826 (11%)
Query: 2484 STQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVF 2543
S PG S+ + C +GY LVG + C + WS P C+ C NG V
Sbjct: 172 SIAPGLSVTYSCESGYLLVGEKIINCLSSGK----WSAVPPTCEEARCKSLGRFPNGKV- 226
Query: 2544 GKE---YTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSIS 2600
KE VG A + C EGY LQ ++ C+ G P C + CP S
Sbjct: 227 -KEPPILRVGVTANFFCDEGYRLQG--PPSSRCVIAGQGVAWTKMPVCEEIFCP--SPPP 281
Query: 2601 VEHGRWRLIFETQYQFQAQLMLICDP------GYYYTGQRVIRC----QANGKWSLGDST 2650
+ +GR + + + CDP + G+ +RC Q G WS
Sbjct: 282 ILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWS--GPA 339
Query: 2651 PTCRI-ISCGELPIPP--NGHRIGTLS---VYGATAIFSCNSGYTLVGSRVRECMANGLW 2704
P C + S + P P G + Y T IF+C G+TL GS+ C A G W
Sbjct: 340 PRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTW 399
Query: 2705 SGSEVRCLAGHCGTPEPIVNGHINGEN---YSYRGSVVYQCNAGFRLIGMSVRICQQDHH 2761
S C C P I+NG + + S+ Y CN G+ L+G C +
Sbjct: 400 EPSAPVC-EKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
Query: 2762 WSGKTPFCVLVSCGHPG-----SPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGL 2816
W+ P C + +C G P H + D V SC L G+ + C
Sbjct: 459 WTPPVPQCKVAACEATGRQLLTKPQHQFVRPD-------VNSSCGEGYKLSGSVYQECQG 511
Query: 2817 DGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDS---FDPGTVMRFSCEAG------HVL 2867
W + C + C P + +G G S F GT + ++C G L
Sbjct: 512 TIPWFMEIRLCKEIT---CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSL 568
Query: 2868 RGSSERTCQAN----GSWSGSQPECGV----ISCGNPGTPSNARVVFSDGLVF-SSSIVY 2918
G S C +N G+WSG P C + + C + + ++ + F + ++ +
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTF 628
Query: 2919 ECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGNDFRYNKTVTYQC 2978
+C G+ G C + TW P C C L G+ + V C
Sbjct: 629 KCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRV---ELVNTSC 685
Query: 2979 VPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVG---SDFMWGSSVT 3035
GY + H + ++ W P+CK + C PPP+I NGK G +F++G+ V+
Sbjct: 686 QDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVS 745
Query: 3036 YACLEGYQLSLPAVFTC----EGNGSWTGELPQCF---PVF-CGDPGVPS--RGRREDRG 3085
Y C +G+ L C +G+GSW+G PQC PV C +P V + +
Sbjct: 746 YECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSA 805
Query: 3086 FSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNS 3145
+S+ V C+P ++ GS C +D TW P+CI C P P+ N++
Sbjct: 806 YSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPP--PKTPNGNHT 863
Query: 3146 QG----YQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANV 3201
G + G ++L+ C +GYLL G C TWS P C +C P
Sbjct: 864 GGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQK 923
Query: 3202 G--ALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPIC 3245
G + G + C++G+ L+ GS C++D W +C
Sbjct: 924 GLEPRKMYQYGAVVTLECEDGYMLE-GSPQSQCQSDHQWNPPLAVC 968
Score = 181 bits (458), Expect = 1e-44
Identities = 163/600 (27%), Positives = 230/600 (38%), Gaps = 75/600 (12%)
Query: 2464 SAPYCSLPRAPLHGFILGQTSTQ------PGGSIHFGCNAGYRLVGHSMAICTRHPQGYH 2517
SAP C + GQ + PG SI + CN GY LVG CT
Sbjct: 402 SAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEG---- 457
Query: 2518 LWSEAIPLCQALSCGLPEAPKNGMVFGKEYT-VGTKAMYSCSEGYHLQAGAEATAECLDT 2576
+W+ +P C+ +C EA ++ ++ V SC EGY L EC T
Sbjct: 458 VWTPPVPQCKVAAC---EATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQ--ECQGT 512
Query: 2577 GLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPG------YYY 2630
W C +TCP I +G + + + C+PG +
Sbjct: 513 IPWFMEI--RLCKEITCPPPPVIY--NGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSL 568
Query: 2631 TGQRVIRCQAN----GKWSLGDSTPTCRI----ISCGELPIPPNGHRIGTLSV---YGAT 2679
G+ IRC +N G WS P C++ + C + I NG++I Y T
Sbjct: 569 IGESTIRCTSNDQERGTWS--GPAPLCKLSLLAVQCSHVHIA-NGYKISGKEAPYFYNDT 625
Query: 2680 AIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSVV 2739
F C SG+TL GS C A+ W C C + G V
Sbjct: 626 VTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVEL---VN 682
Query: 2740 YQCNAGFRLIGMSVRICQQDHH--WSGKTPFCVLVSCGHPGSPP------HSQMSGDSYT 2791
C G++L G + ++CQ + W K P C ++ C HP PP H+ M +++
Sbjct: 683 TSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHC-HP--PPVIVNGKHTGMMAENFL 739
Query: 2792 VGAVVRYSCIGKRTLVGNSTRMCGLD----GHWTGSLPHC-SGTSVGVCGDPGIPAHGIR 2846
G V Y C L+G C D G W+G P C V C +P + HG +
Sbjct: 740 YGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVK-HGYK 798
Query: 2847 LG---DSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPEC---GVISCGNPGTPS 2900
L ++ ++ C G ++ GS C + +W P C I C P
Sbjct: 799 LNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTP 858
Query: 2901 NARVVFSDGLVFSS--SIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDP--- 2955
N + FS SI+Y C +GY G C+ GTW+ P C +NC P
Sbjct: 859 NGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADM 918
Query: 2956 -GIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKP 3014
GI GL ++Y VT +C GYM+E S C D WN VC++ P
Sbjct: 919 DGI-QKGLEPRKMYQYGAVVTLECEDGYMLEGSPQS--QCQSDHQWNPPLAVCRSRSLAP 975
Score = 93.6 bits (231), Expect = 3e-18
Identities = 76/275 (27%), Positives = 120/275 (43%), Gaps = 24/275 (8%)
Query: 3005 PVCKALMCKPPPLIPNGKV--VGSDFMWGSSVTYACLEGYQL----SLPAVFTCEGNGSW 3058
P + C PP I NG++ + G+ + Y+C ++L SL + + +G+W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 3059 TGELPQC--FPVF--CGDPGVPSRGR-REDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSD 3113
P+C F + C +P VP + R + + SV+F+C + G+ +CQ++
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 3114 GTWSGTQ-PSCIDPTLTTCADPGVPQFG----IQNNSQGYQVGSTVLFRCQKGYLLQGST 3168
W T+ P+C+ C P +P N G +V + C+ GYLL G
Sbjct: 136 NMWGPTRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEK 193
Query: 3169 TRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSE 3228
CL + WS PP C C+ + V + +G T + C EG+ L+G
Sbjct: 194 IINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPS 253
Query: 3229 HRTCKADG---SWTGKPPICLEV-RPSGRPINTAR 3259
R C G +WT K P+C E+ PS PI R
Sbjct: 254 SR-CVIAGQGVAWT-KMPVCEEIFCPSPPPILNGR 286
Score = 92.4 bits (228), Expect = 7e-18
Identities = 221/1051 (21%), Positives = 360/1051 (34%), Gaps = 225/1051 (21%)
Query: 1722 FVYQAVPRTSATQCSSVPEPRYGK--RLGSDFSVGAIVRFECNSGYALQGSPEIECLPVP 1779
F+ P C S P G+ + +VG ++R+ C+ + L G + C+
Sbjct: 10 FLALVAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKD 69
Query: 1780 GALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVV 1839
W+ AP C Y N + + +VP G I+
Sbjct: 70 KVDGTWDKPAPKC----------------------EYFNKYSSCPEPIVPGGYKIR---- 103
Query: 1840 SFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHL 1899
S G T +FS ++ +N + + + + F L
Sbjct: 104 --------GSTPYRHGDSVTFACKTNFSMNGNKSVWCQANN---MWGPTRLPTCVSVFPL 152
Query: 1900 EYKTVGLSSCPEPAVPSNGVKTGERYLVNDV-----VSFQCEPGYALQGHAHISCMPGTV 1954
E CP + NG T E V + V++ CE GY L G I+C+
Sbjct: 153 E--------CPALPMIHNGHHTSEN--VGSIAPGLSVTYSCESGYLLVGEKIINCLSSG- 201
Query: 1955 RRWNYPPPLCI-AQC-------GGTVEEMEGVILSPGFPGNY----------PSNMDC-- 1994
+W+ PP C A+C G V+E IL G N+ P + C
Sbjct: 202 -KWSAVPPTCEEARCKSLGRFPNGKVKEPP--ILRVGVTANFFCDEGYRLQGPPSSRCVI 258
Query: 1995 -----SW-KIAL----------PVGFGAHI----------QFLNFSTEPNHD----YIEI 2024
+W K+ + P+ G HI + ++ +P+ + +I I
Sbjct: 259 AGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILI 318
Query: 2025 RNGPYET---SRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQ 2081
S+ G +SG P LSTS H Q G + Q Y++
Sbjct: 319 GESTLRCTVDSQKTGTWSGPA-PRCELSTSA-----VQCPHPQILRGRMVSGQKDRYTYN 372
Query: 2082 ---ISSFLRGFDLSELERTNSTPPVAASYVWDLD-PGCEAYELQECPDPEPFANG----- 2132
I + + GF L ++ A W+ P CE +EC P NG
Sbjct: 373 DTVIFACMFGFTLKGSKQIRCN----AQGTWEPSAPVCE----KECQAPPNILNGQKEDR 424
Query: 2133 -IVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPC--------- 2182
+VR ++ G S+ + C PGY L G + C + W P+P+C+V
Sbjct: 425 HMVR---FDPGTSIKYSCNPGYVLVGEESIQCT--SEGVWTPPVPQCKVAACEATGRQLL 479
Query: 2183 --------GGNITSSNGTVYSPGFPSPYSSSQDCV-WLITV-----------PIGHGVRL 2222
++ SS G Y S Y Q + W + + P+ +
Sbjct: 480 TKPQHQFVRPDVNSSCGEGYKLS-GSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAH 538
Query: 2223 NLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIF 2282
S L+ P G +T P P GV + + T++ +SN G
Sbjct: 539 TGSSLEDFPYGTTVTYTCNP---GPERGVEFSLIGESTIRCTSND-----QERGTWSGPA 590
Query: 2283 AIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYL 2342
+ + +C I ++ + + D V ++C GFTL G+ + CK
Sbjct: 591 PLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADN-- 648
Query: 2343 QFEGPPPICE------VHCPTNELLTDSTGVILSQSYPGSYP----QFQTCS------WL 2386
++ P+CE V EL S +++ S Y +Q C W
Sbjct: 649 TWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWF 708
Query: 2387 VRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNY--SAPLIVTSSSNSV 2444
++ I + ++ + G + G Y + S +
Sbjct: 709 KKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKG 768
Query: 2445 YLRWSSDHAYNRKGFKIRYSAPYCSLPRAPL-HGFILGQTST--QPGGSIHFGCNAGYRL 2501
+ WS + S P P + HG+ L +T + ++ CN G+ +
Sbjct: 769 HGSWSGPSP------QCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIM 822
Query: 2502 VGHSMAICTRHPQGYHLWSEAIPLC-QALSCGLPEAPK--NGMVFG---KEYTVGTKAMY 2555
G + C + W +P C + G P PK NG G ++ G +Y
Sbjct: 823 NGSRVIRCHTD----NTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILY 878
Query: 2556 SCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSI-SVEHGRWRLIFETQY 2614
SC +GY L EA C G WS P C V C + + ++ G L Y
Sbjct: 879 SCDQGYLLV--GEALLLCTHEGTWS--QPAPHCKEVNCSSPADMDGIQKG---LEPRKMY 931
Query: 2615 QFQAQLMLICDPGYYYTGQRVIRCQANGKWS 2645
Q+ A + L C+ GY G +CQ++ +W+
Sbjct: 932 QYGAVVTLECEDGYMLEGSPQSQCQSDHQWN 962
Score = 67.4 bits (163), Expect = 2e-10
Identities = 174/851 (20%), Positives = 275/851 (32%), Gaps = 179/851 (21%)
Query: 1031 FSEYDLEPCEEPEVPA-YSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWS- 1088
F++Y C EP VP Y IR + GD++TF+C + + G + C +W
Sbjct: 85 FNKYS--SCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANN--MWGP 140
Query: 1089 SPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEG 1148
+ LP CV+ L P P+ +N +H PG + + L G
Sbjct: 141 TRLPTCVSVF---------PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVG 191
Query: 1149 DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFEL 1208
+ + +N SS W E
Sbjct: 192 EKI-------------------------INCLSSGKWSAVPPTCEEA------------- 213
Query: 1209 IKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLC-LSGERRTWDRPLPTC 1267
+C+ G G G + +F CD GY L+G C ++G+ W + +P C
Sbjct: 214 -RCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTK-MPVC 271
Query: 1268 VA-------------ECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHF 1314
G ++ G +++ E +N I E+ CT+
Sbjct: 272 EEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTV---- 327
Query: 1315 LVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHS----------TFNSVVLQFST 1364
D+++ W GP L P+ L T+N V+
Sbjct: 328 ---DSQKTGT----WSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACM 380
Query: 1365 DFFTSKQGFAIQFSVSTA---------TSCNDPGIPQNGSRSGDS---WEAGDSTVFQCD 1412
FT K I+ + C P NG + ++ G S + C+
Sbjct: 381 FGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCN 440
Query: 1413 PGYALQGSAEISCVKIENRFFWQPSPPTC-IAPCGGD----LTGPSGVILSPNYPEPYPP 1467
PGY L G I C + W P P C +A C LT P + P+
Sbjct: 441 PGYVLVGEESIQCT---SEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGE 497
Query: 1468 GKECDWKV------TVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQL- 1520
G + V T+ I L I P IY+G + S L YG+ +
Sbjct: 498 GYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPV----IYNGAHTGSSLEDFPYGTTVT 553
Query: 1521 ----PGRIESSSNSLF--LAFRSDASVSNAGFVIDYTENPRESC--------FDPGSIKN 1566
PG SL R ++ G P C I N
Sbjct: 554 YTCNPGPERGVEFSLIGESTIRCTSNDQERG----TWSGPAPLCKLSLLAVQCSHVHIAN 609
Query: 1567 GTRVG---SDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVC-------- 1615
G ++ + +VT+ C+ G+ ++G+S + C W+ PVC
Sbjct: 610 GYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC----KADNTWDPEIPVCEKETCQHV 665
Query: 1616 -----TAPCGGQY-----VGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFH 1665
P G + DG L+ + Q + ++F +P V+ H
Sbjct: 666 RQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVI-----HCH 720
Query: 1666 TALNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQ 1725
V H G + L + + L ++ + +KG G Q
Sbjct: 721 PPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPS--PQ 778
Query: 1726 AVPRTSATQCSSVPEPRYGKRLG---SDFSVGAIVRFECNSGYALQGSPEIECLPVPGAL 1782
+ T+C + PE ++G +L S +S IV +CN G+ + GS I C
Sbjct: 779 CLRSPPVTRCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRC----HTD 833
Query: 1783 AQWNVSAPTCV 1793
W PTC+
Sbjct: 834 NTWVPGVPTCI 844
Score = 63.9 bits (154), Expect = 3e-09
Identities = 211/1028 (20%), Positives = 353/1028 (34%), Gaps = 187/1028 (18%)
Query: 520 SCGDPGIPAYGRRE--GSRFHHGDTLKFECQPAFELVGQKAITC----QKNNQWSAKKPG 573
SCG P GR + G +++ C F L+G+K++ C + + W P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 574 CVFSCFFNFTS------PSGVVLSPNYPEDYGNHLH--CVWLILARPESRIHLAFNDIDV 625
C + F ++S P G + + P +G+ + C + N++
Sbjct: 82 CEY--FNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWG 139
Query: 626 EPQFDFLV------------IKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHS 673
+ V I +G V G + S S + + S
Sbjct: 140 PTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLS 199
Query: 674 TGKRGFNITFTTFRHNECPDPGVPVNGK-RFGDSLQLGSSISFLCDEGFLGTQGSETITC 732
+GK ++ T C G NGK + L++G + +F CDEG+ QG + C
Sbjct: 200 SGK--WSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYR-LQGPPSSRC 256
Query: 733 VLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKI 792
V+ V W + CE I P P + G +
Sbjct: 257 VIAGQGVAWTKMPV-CEE------------IFCPSPPPILNGRHIGNSLANVSYGSIVTY 303
Query: 793 TFDRFKTE-VNYDTLEVRDGR-TYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSD 850
T D E VN+ + R T + G + G P+ +STS + H
Sbjct: 304 TCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGP-APRCELSTS-------AVQCPHPQ 355
Query: 851 IGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPN 910
I LR ++ Q D + V F+C G+TL + + C
Sbjct: 356 I---LRGRMVSGQKDR----------------YTYNDTVIFACMFGFTLKGSKQIRCNAQ 396
Query: 911 FQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFH 970
W + P CE C P+ ++ G + ++ + +
Sbjct: 397 GTWEPSAPVCEKEC-------------QAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGY 443
Query: 971 LESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFI-SDFSMSY-EGFN 1028
+ G + + T G +T P+ Q ++ A + G Q +F+ D + S EG+
Sbjct: 444 VLVGEESIQCTSEGVWTPPVPQ---CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYK 500
Query: 1029 ITFSEY-----------DLEPCEEPEVP--------AYSIRKGLQFGVGDTLTFSCFPG- 1068
++ S Y ++ C+E P A++ F G T+T++C PG
Sbjct: 501 LSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGP 560
Query: 1069 -----YRLEGTARITCLGG--RRRLWSSPLPRC-----VAECGNSVTGTQGTLLSPNFPV 1116
+ L G + I C R WS P P C +C + + P
Sbjct: 561 ERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPY 620
Query: 1117 NYNN--NHECIYSIQTQPGKGIQLKARAFELSEGDV----LKVYDGNNNSARLLGVFSHS 1170
YN+ +C YS T G Q++ +A + ++ + S + L S
Sbjct: 621 FYNDTVTFKC-YSGFTLKGSS-QIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRV 678
Query: 1171 EMMGVTLNS--TSSSLWLDFITDAENTSKGFELHFSSFELIK---CEDPGTPKFGYK--V 1223
E++ + + DAEN + F L K C P G +
Sbjct: 679 ELVNTSCQDGYQLTGHAYQMCQDAEN-----GIWFKKIPLCKVIHCHPPPVIVNGKHTGM 733
Query: 1224 HDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGER--RTWDRPLPTCVAECGGT--VRGEV 1279
E G+ VS+ CD G+ L G ++L C S + +W P P C+ T EV
Sbjct: 734 MAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEV 793
Query: 1280 S-GQVLSPGYPAPYEHNLNCIWTIEAEAGCTI-GLHFLVFDTEEVHDVLRIWDGPVESGV 1337
G L+ + A Y H N I ++ G + G + T+ W V + +
Sbjct: 794 KHGYKLNKTHSA-YSH--NDIVYVDCNPGFIMNGSRVIRCHTDNT------WVPGVPTCI 844
Query: 1338 LLKELSGPALPKDLHSTF-NSVVLQFS---TDFFTSKQGF-----AIQFSVSTAT----- 1383
+ P PK + + +FS + ++ QG+ A+ T
Sbjct: 845 KKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPA 904
Query: 1384 ------SCNDP----GIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFF 1433
+C+ P GI Q G ++ G +C+ GY L+GS + C ++
Sbjct: 905 PHCKEVNCSSPADMDGI-QKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC---QSDHQ 960
Query: 1434 WQPSPPTC 1441
W P C
Sbjct: 961 WNPPLAVC 968
Score = 54.7 bits (130), Expect = 2e-06
Identities = 109/476 (22%), Positives = 164/476 (34%), Gaps = 98/476 (20%)
Query: 1557 SCFDPGSIKNG--TRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPV 1614
SC P I NG + + + +G+ + Y C G + + G +L CI W+ P P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 1615 C------------TAPCGGQYVGS------DGVVLS--PNYPQNYTSGQIC----LYFVT 1650
C P G + GS D V + N+ N C ++ T
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 1651 VPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLS---SLSGSHTGESLPLATSNQVLI 1707
V + F + +H+GH + S LS +++ ES L +++
Sbjct: 142 RLPTCV-----SVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIIN 196
Query: 1708 KFSAKGLAPARGFHFVYQAVPRT-SATQCSSVPEPRYGK-RLGSDFSVGAIVRFECNSGY 1765
S+ + AVP T +C S+ GK + VG F C+ GY
Sbjct: 197 CLSSG----------KWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGY 246
Query: 1766 ALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWK 1825
LQG P C+ + G W P C I P P P LN +
Sbjct: 247 RLQGPPSSRCV-IAGQGVAW-TKMPVC------------EEIFCPS-PPPILNGRH---- 287
Query: 1826 IVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLH 1885
G + VS+ + + + N + + S TV + T +
Sbjct: 288 ------IGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPR 341
Query: 1886 FYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTG--ERYLVNDVVSFQCEPGYALQG 1943
++S SA CP P + + +G +RY ND V F C G+ L+G
Sbjct: 342 --CELSTSAV------------QCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKG 387
Query: 1944 HAHISC-MPGTVRRWNYPPPLCIAQC-------GGTVEEMEGVILSPGFPGNYPSN 1991
I C GT W P+C +C G E+ V PG Y N
Sbjct: 388 SKQIRCNAQGT---WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCN 440
Score = 49.3 bits (116), Expect = 7e-05
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 499 QTDGSGSSLGFKASYEEIEQGSCGDPGIPA-YGRREGSRFHHGDTLKFECQPAFELVGQK 557
+ DG+ K Y + SC +P +P Y R + + HGD++ F C+ F + G K
Sbjct: 70 KVDGTWDKPAPKCEYFN-KYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNK 128
Query: 558 AITCQKNNQWS-AKKPGCV 575
++ CQ NN W + P CV
Sbjct: 129 SVWCQANNMWGPTRLPTCV 147
Score = 47.4 bits (111), Expect = 3e-04
Identities = 61/274 (22%), Positives = 96/274 (35%), Gaps = 63/274 (22%)
Query: 1558 CFDPGSIKNGTRVG---SDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPV 1614
C P I NG G + G+ V+Y C G+ + G L C G W+ P P
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778
Query: 1615 CTAPCGGQYVGSDGVVLSPN------YPQNYTSGQIC---LYFVTVPKDYVVFGQFAFFH 1665
C + S V PN Y N T + +V +++ G
Sbjct: 779 C--------LRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNG------ 824
Query: 1666 TALNDVVEVHDGHSQHSRLLSSL--------------SGSHTGESLPLATSNQVLIKFSA 1711
+ V+ H ++ + + + +G+HTG ++ + ++
Sbjct: 825 ---SRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCD 881
Query: 1712 KG---------LAPARGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSD----FSVGAIVR 1758
+G L G Q P CSS P G + G + + GA+V
Sbjct: 882 QGYLLVGEALLLCTHEGTWS--QPAPHCKEVNCSS-PADMDGIQKGLEPRKMYQYGAVVT 938
Query: 1759 FECNSGYALQGSPEIECLPVPGALAQWNVSAPTC 1792
EC GY L+GSP+ +C + QWN C
Sbjct: 939 LECEDGYMLEGSPQSQC----QSDHQWNPPLAVC 968
Score = 45.8 bits (107), Expect = 7e-04
Identities = 108/506 (21%), Positives = 169/506 (33%), Gaps = 139/506 (27%)
Query: 137 HTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
HT N G + G+ V YSC G+ L G ++ C + S W P+C
Sbjct: 165 HTSENVGSIAPGLS----------VTYSCESGYLLVGEKIINCLS----SGKWSAVPPTC 210
Query: 197 RADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFL 256
+ C R +G + P + +G T +F ++GY
Sbjct: 211 E-EARCKSLGRFPNGKVKEPP---------------ILRVGVTA-----NFFCDEGY--- 246
Query: 257 EVTGTEGSSLWFTGASL---------------PAPVISSKNWLRLHFTSDGNHRQRGFSA 301
+ G S G + P P+++ + H + + G
Sbjct: 247 RLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGR-----HIGNSLANVSYGSIV 301
Query: 302 QYQV----KKQIELKSRGVKLMPSKDNSQKTSVLT----QVGVSQGHNMCPDPGIPERGK 353
Y ++ + G + +SQKT + + +S CP P I RG+
Sbjct: 302 TYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQIL-RGR 360
Query: 354 RLGSD---FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLR 410
+ + +V F C G+ L+GSK+I C + W PVC + C A
Sbjct: 361 MVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRC----NAQGTWEPSAPVCE-KECQA--- 412
Query: 411 GPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGD 470
PN + H V +P IK + GY + G++
Sbjct: 413 -------PPNILNGQKEDRHMV----RFDPGTSIK-----YSCNPGYVLV-----GEESI 451
Query: 471 QKTVLYILTGTSVPDLIVS----------TNHQMWLLFQTDGSGSSLGFKAS---YEEIE 517
Q T + T VP V+ T Q + S G+K S Y+E +
Sbjct: 452 QCTSEGVWT-PPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQ 510
Query: 518 -------------QGSCGDPGIPAYGRREGSR---FHHGDTLKFECQPA------FELVG 555
+ +C P + G GS F +G T+ + C P F L+G
Sbjct: 511 GTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIG 570
Query: 556 QKAITCQKNNQ----WSAKKPGCVFS 577
+ I C N+Q WS P C S
Sbjct: 571 ESTIRCTSNDQERGTWSGPAPLCKLS 596
Score = 45.4 bits (106), Expect = 0.001
Identities = 58/245 (23%), Positives = 91/245 (37%), Gaps = 45/245 (18%)
Query: 359 FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITS 418
F G+S++++CN GY L G + I C W+ P C+ C+A R ++T
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSE----GVWTPPVPQCKVAACEATGR---QLLTK 481
Query: 419 PNFP-IQYDNNAHC------------------VWI--------ITALNPSKVIKLAFEEF 451
P ++ D N+ C W IT P + A
Sbjct: 482 PQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGS 541
Query: 452 DLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKA 511
LE TV G ++ V + L G S + ++N Q + SG + K
Sbjct: 542 SLEDFPYGTTVTYTCNPGPERGVEFSLIGEST--IRCTSNDQE----RGTWSGPAPLCKL 595
Query: 512 SYEEIEQGSCGDPGIPAYGRREGSR--FHHGDTLKFECQPAFELVGQKAITCQKNNQWSA 569
S ++ C I + G + + DT+ F+C F L G I C+ +N W
Sbjct: 596 SLLAVQ---CSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDP 652
Query: 570 KKPGC 574
+ P C
Sbjct: 653 EIPVC 657
Score = 44.7 bits (104), Expect = 0.002
Identities = 66/282 (23%), Positives = 100/282 (35%), Gaps = 46/282 (16%)
Query: 139 CGNPGRLPNGIQQG---STFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
C P + NG G F G++V Y C+ GF+L G L C + S+ +W P P
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778
Query: 196 CRAD---DACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG 252
C C ++ H S Y +N +V++D
Sbjct: 779 CLRSPPVTRCPNPEVKHGYKLNKTH--SAYSHN---------------DIVYVDCNPGFI 821
Query: 253 YDFLEVTGTEGSSLWFTGASLPAPVISSKNWLRL---HFTSDGNHR-------QRGFSAQ 302
+ V + W G P K ++ T +GNH G S
Sbjct: 822 MNGSRVIRCHTDNTWVPG----VPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSIL 877
Query: 303 YQVKKQIELKSRGVKLMPSKDN-SQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRL 361
Y + L + L + SQ +V S +M GI ++G ++
Sbjct: 878 YSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADM---DGI-QKGLEPRKMYQY 933
Query: 362 GSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRAR 403
G+ V C +GY L+GS + C SD W+ VCR+R
Sbjct: 934 GAVVTLECEDGYMLEGSPQSQCQ--SD--HQWNPPLAVCRSR 971
Score = 43.9 bits (102), Expect = 0.003
Identities = 54/222 (24%), Positives = 81/222 (36%), Gaps = 47/222 (21%)
Query: 360 RLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSP 419
R+G + F C+EGY LQG C+ ++ AW+ PVC C + P I+
Sbjct: 233 RVGVTANFFCDEGYRLQGPPSSRCV-IAGQGVAWT-KMPVCEEIFCPS----PPPILNGR 286
Query: 420 NFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILT 479
+ N ++ + +P D E G + + +G+ + TV T
Sbjct: 287 HIGNSLANVSYGSIVTYTCDP-----------DPEEGVNFILIGESTL---RCTVDSQKT 332
Query: 480 GTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRR---EGSR 536
GT W SG + + S ++ C P I GR + R
Sbjct: 333 GT-------------W-------SGPAPRCELSTSAVQ---CPHPQI-LRGRMVSGQKDR 368
Query: 537 FHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSC 578
+ + DT+ F C F L G K I C W P C C
Sbjct: 369 YTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKEC 410
Score = 43.5 bits (101), Expect = 0.004
Identities = 79/353 (22%), Positives = 120/353 (33%), Gaps = 67/353 (18%)
Query: 87 PQPENLRTRLTGFQLP------ATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCG 140
P P+ LR R+ Q I + +L+ +AQG + C
Sbjct: 352 PHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQ 411
Query: 141 NPGRLPNGIQQGS---TFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCR 197
P + NG ++ F+ G ++YSCN G+ L G + C + W P+P C+
Sbjct: 412 APPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQC----TSEGVWTPPVPQCK 467
Query: 198 ADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLE 257
AC T G+ + H N+ C G+ L G + E
Sbjct: 468 V-AACEAT--GRQLLTKPQHQFVRPDVNSSC--------GEGYKL--------SGSVYQE 508
Query: 258 VTGTEGSSLWFTGASL-------PAPVISSKNWLRLHFTSDGNHRQRGFSAQYQV----K 306
GT WF L P PVI + H S G + Y +
Sbjct: 509 CQGT---IPWFMEIRLCKEITCPPPPVI----YNGAHTGSSLEDFPYGTTVTYTCNPGPE 561
Query: 307 KQIELKSRGVKLMPSKDNSQKTSV---------LTQVGVSQGHNMCPDPGIPERGKRLGS 357
+ +E G + N Q+ L+ + V H + G GK +
Sbjct: 562 RGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIAN-GYKISGKE--A 618
Query: 358 DFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLR 410
+ +V F C G+ L+GS +I C + W PVC C H+R
Sbjct: 619 PYFYNDTVTFKCYSGFTLKGSSQIRCKADN----TWDPEIPVCEKETCQ-HVR 666
Score = 42.0 bits (97), Expect = 0.011
Identities = 99/509 (19%), Positives = 158/509 (31%), Gaps = 138/509 (27%)
Query: 138 TCGNPGRLPNGIQQGST---FNLGDKVRYSCNLG------FFLEGHAVLTCHAGSENSAT 188
TC P + NG GS+ F G V Y+CN G F L G + + C + + T
Sbjct: 526 TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGT 585
Query: 189 WDFPLPSCRAD---DACGGTLRGQSGIISSPHFPSEYHN--------------------N 225
W P P C+ C IS P Y++
Sbjct: 586 WSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCK 645
Query: 226 ADCTW----------------TILAELGDTIALVFIDFQLEDGYDF----LEVTGTEGSS 265
AD TW L EL + ++ +DGY ++ +
Sbjct: 646 ADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENG 705
Query: 266 LWFTGASL-------PAPVISSKNWLRLHFTSDGNHRQRGFSAQYQV--------KKQIE 310
+WF L P PVI + H + G Y+ +K+++
Sbjct: 706 IWFKKIPLCKVIHCHPPPVIVNGK----HTGMMAENFLYGNEVSYECDQGFYLLGEKKLQ 761
Query: 311 LKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGK--RLGSDFRLGSSVQFT 368
+S SK + + Q S CP+P + K + S + V
Sbjct: 762 CRS------DSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVD 815
Query: 369 CNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARM---CDAHLRGPSGIITSPNFPIQY 425
CN G+ + GS+ I C + W P C + C + P+G T N
Sbjct: 816 CNPGFIMNGSRVIRCHTDN----TWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGN----- 866
Query: 426 DNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPD 485
I +P I + ++GY L VG+
Sbjct: 867 ---------IARFSPGMSIL-----YSCDQGY--LLVGEA-------------------- 890
Query: 486 LIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKF 545
L++ T+ W + A + I++ G + +G +
Sbjct: 891 LLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQK-----------GLEPRKMYQYGAVVTL 939
Query: 546 ECQPAFELVGQKAITCQKNNQWSAKKPGC 574
EC+ + L G CQ ++QW+ C
Sbjct: 940 ECEDGYMLEGSPQSQCQSDHQWNPPLAVC 968
Score = 40.8 bits (94), Expect = 0.024
Identities = 24/61 (39%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
Query: 138 TCGNPGRLPNG-IQQGST-FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
+CG+P + NG I ST +G +RYSC+ F L G L C + TWD P P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 196 C 196
C
Sbjct: 82 C 82
Score = 39.3 bits (90), Expect = 0.069
Identities = 57/265 (21%), Positives = 103/265 (38%), Gaps = 34/265 (12%)
Query: 691 CPDPGVPVNGKRFG---DSLQLGSSISFLCDEGFLGTQGSETITCVL-KEGSVVWNSAVL 746
C P V VNGK G ++ G+ +S+ CD+GF G + + C +G W+
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFY-LLGEKKLQCRSDSKGHGSWSGPSP 777
Query: 747 RC-EAPCGGHLTSPS---GTILSPGWPGFYKDALSCAWVIEAQPGYPIK----ITFDRFK 798
+C +P +P G L+ + + + ++ PG+ + I
Sbjct: 778 QCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIV---YVDCNPGFIMNGSRVIRCHTDN 834
Query: 799 TEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQL--- 855
T V ++ P +G + S + +L+S D+ + +G L
Sbjct: 835 TWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLC 894
Query: 856 -RYETITLQSDHCLDPGIP----VNGQRHGND----FYVGALVTFSCDSGYTLSDGEPLE 906
T + + HC + ++G + G + + GA+VT C+ GY L +
Sbjct: 895 THEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQ 954
Query: 907 CEPNFQWSRALPSCEA------LCG 925
C+ + QW+ L C + LCG
Sbjct: 955 CQSDHQWNPPLAVCRSRSLAPVLCG 979
Score = 39.3 bits (90), Expect = 0.069
Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 2/66 (3%)
Query: 2113 PGCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWD 2172
P C+ D + G+ Y G VT EC GY L G P CQ ++ W+
Sbjct: 905 PHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQ--SDHQWN 962
Query: 2173 HPLPKC 2178
PL C
Sbjct: 963 PPLAVC 968
Score = 35.8 bits (81), Expect = 0.76
Identities = 16/45 (35%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
Query: 340 HNMCPDPGIPERGKRLGSD-FRLGSSVQFTCNEGYDLQGSKRITC 383
++ CP+P +P K GS +R G SV F C + + G+K + C
Sbjct: 88 YSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWC 132
Score = 33.9 bits (76), Expect = 2.9
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 1902 KTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPP 1961
K V SS + G++ + Y VV+ +CE GY L+G C + +WN P
Sbjct: 908 KEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQ--SDHQWNPPL 965
Query: 1962 PLC 1964
+C
Sbjct: 966 AVC 968
Score = 32.7 bits (73), Expect = 6.5
Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 8/65 (12%)
Query: 135 PSHTCGNPGRLPNGIQQGST---FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDF 191
P C NP + +G + T ++ D V CN GF + G V+ CH + TW
Sbjct: 784 PVTRCPNP-EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDN----TWVP 838
Query: 192 PLPSC 196
+P+C
Sbjct: 839 GVPTC 843
>gi|32261332 seizure related 6 homolog (mouse)-like precursor [Homo
sapiens]
Length = 1024
Score = 260 bits (665), Expect = 1e-68
Identities = 207/717 (28%), Positives = 330/717 (46%), Gaps = 81/717 (11%)
Query: 1096 AECGNSVTGTQGTLLSPNFPV-NYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVY 1154
A C S + +G + S ++P+ NN EC Y++ G G++L+ ++ LS+G++L +
Sbjct: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIR 338
Query: 1155 DGNNNSARLLGVFSHSEMM--GVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCE 1212
+ + L V ++ ++ G + S ++++ + F T ++ F+LH+ +F ++ C
Sbjct: 339 GVDGPT---LTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAF-MLSCN 394
Query: 1213 DPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECG 1272
P P G + H +G F C GY L+G++ L C++ + W P C A CG
Sbjct: 395 FPRRPDSGDVTVMDLH-SGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCG 453
Query: 1273 GTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHF---LVFDTEEVHDVLRIW 1329
G V G+VLSP YP + CIWTIEA G + LHF L+ D D + +
Sbjct: 454 GAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHD----KDRMTVH 509
Query: 1330 DGPV-ESGVLLKELSGPALP-KDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCND 1387
G +S +L L ++P + L S N++ ++F++D + F I+F C +
Sbjct: 510 SGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYE 569
Query: 1388 PGIPQNG--SRSGDSWEAGDSTVFQCDPGYAL-QGSAEISCVKIENRFFWQPSPPTCIAP 1444
P I QNG + S ++ G F CDPG++L QG A I C+ + + +W + P C A
Sbjct: 570 PYI-QNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDP-YWNDTEPLCRAM 627
Query: 1445 CGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDG 1504
CGG+L+ +GV+LSPN+PEPY G++C WK+ V + I L NL D L IYDG
Sbjct: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLS-NSDILTIYDG 686
Query: 1505 RDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDAS----VSNAGFVIDYTENPR-ESCF 1559
+ + ++G + G+ P ++ SS+ L + F SD + GF+++Y E R +SC
Sbjct: 687 DEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCS 746
Query: 1560 DPGSIKNGTRVGSDLKL--GSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTA 1617
D I+NG + S +L G+ +TY C GY++ G+ TL+C W++ P C
Sbjct: 747 DLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTC----QWDLSWSSDPPFCEK 802
Query: 1618 PCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDG 1677
Y G V ++ S + L T+ Y F ++L G
Sbjct: 803 I---MYCTDPGEV---DHSTRLISDPVLLVGTTI--QYTCNPGFVLEGSSLLTCYSRETG 854
Query: 1678 HSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSS 1737
+ L H LA N L P G+ +Y
Sbjct: 855 TPIWTSRL-----PHCVSEESLACDNPGL---------PENGYQILY------------- 887
Query: 1738 VPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVV 1794
KRL + G + F C G+ L G I C + G + WN P C V
Sbjct: 888 -------KRL---YLPGESLTFMCYEGFELMGEVTIRC--ILGQPSHWNGPLPVCKV 932
Score = 188 bits (477), Expect = 9e-47
Identities = 166/609 (27%), Positives = 259/609 (42%), Gaps = 69/609 (11%)
Query: 1617 APCGGQYVGSDGVVLSPNYPQNYTSGQI-CLYFVTVPKDYVVFGQFAFFHTALNDVVEVH 1675
A C + +G + S +YP + + C Y VTV Y V Q + + +++ +
Sbjct: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIR 338
Query: 1676 DGHSQHSRLLSSLSGSHTGESL--PLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSAT 1733
+L++ + G+ + P T + F GL F YQA
Sbjct: 339 GVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGT---FQLHYQAF----ML 391
Query: 1734 QCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCV 1793
C+ P G D G + F C+ GY LQG+ + C + + W+ P C
Sbjct: 392 SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTC--INASKPHWSSQEPICS 449
Query: 1794 VPCGGNLTERR-GTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEV 1852
PCGG + G +LSP +PE S C+W I PEG + + + D + V
Sbjct: 450 APCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTV 508
Query: 1853 FDGADNTVTML-GSFSGTTVPAL-LNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCP 1910
G N +L S +VP L S N + + F SD + +A+ F++ ++ C
Sbjct: 509 HSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCY 568
Query: 1911 EPAVPSNGVKTGE-RYLVNDVVSFQCEPGYAL-QGHAHISCMPGTVRRWNYPPPLCIAQC 1968
EP + + T + Y + +V F C+PG++L QG A I C+ WN PLC A C
Sbjct: 569 EPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMC 628
Query: 1969 GGTVEEMEGVILSPGFPGNYPSNMDCSWKIAL--PVGFGAHIQFLNFSTEPNHDYIEIRN 2026
GG + + GV+LSP +P Y DC WKI + IQFLN S N D + I +
Sbjct: 629 GGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLS---NSDILTIYD 685
Query: 2027 GPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHS----QNRPGFKLEYQDLTYSHQI 2082
G ++G++ G+ P L S++ + T+ FHSD + GF + Y +++ +
Sbjct: 686 GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSC 745
Query: 2083 SSFLRGFDLSELER----TNSTPPVAASYV-------------------WDLD-----PG 2114
S DL E++ T+ T V + + WDL P
Sbjct: 746 S------DLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPF 799
Query: 2115 CEAYELQECPDP--EPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTC---QHGTNR 2169
CE ++ C DP + ++ VG ++ + C PG+ L G +LTC + GT
Sbjct: 800 CE--KIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGT-P 856
Query: 2170 NWDHPLPKC 2178
W LP C
Sbjct: 857 IWTSRLPHC 865
Score = 187 bits (476), Expect = 1e-46
Identities = 155/539 (28%), Positives = 236/539 (43%), Gaps = 34/539 (6%)
Query: 404 MCDAHLRGPSGIITSPNFPIQYDNN-AHCVWIITALNPSKVIKLAFEEFDLERGYDTLTV 462
+C P G I S ++P+ NN C + +T V +L + +L G + L++
Sbjct: 280 LCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGV-ELQVKSVNLSDG-ELLSI 337
Query: 463 GDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQT---DGSGSSLGFKASYEEIEQG 519
G DG TVL T +I S + + + F+T DG G+ F+ Y+
Sbjct: 338 R--GVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGT---FQLHYQAFML- 391
Query: 520 SCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITC--QKNNQWSAKKPGCVFS 577
SC P P G H G F C +EL G K +TC WS+++P C
Sbjct: 392 SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAP 451
Query: 578 C---FFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVI 634
C N T G VLSP+YPE+ C+W I A ++HL F + + + D + +
Sbjct: 452 CGGAVHNAT--IGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTV 508
Query: 635 KDGATAEAPVL-GTFSGNQLP-SSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECP 692
G T ++ +L + +P + S G+ R+EF +D + FNI F F C
Sbjct: 509 HSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCY 568
Query: 693 DPGVPVNGKRFGD-SLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAP 751
+P + D + +G+ + F CD G QG I C+ WN C A
Sbjct: 569 EPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECI-NVRDPYWNDTEPLCRAM 627
Query: 752 CGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFD-RFKTEVNYDTLEVRD 810
CGG L++ +G +LSP WP Y + C W I G +I D +F N D L + D
Sbjct: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHV--GEEKRIFLDIQFLNLSNSDILTIYD 685
Query: 811 GRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKS----HSDIGFQLRYETITLQSDH 866
G ++G Y G PQ L S++ L + F +D + GF + Y ++ ++D
Sbjct: 686 GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVS-RNDS 744
Query: 867 CLDPGIPVNGQR--HGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEAL 923
C D NG + + GA +T+ CD GY + + L C+ + WS P CE +
Sbjct: 745 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 803
Score = 185 bits (470), Expect = 6e-46
Identities = 189/774 (24%), Positives = 297/774 (38%), Gaps = 86/774 (11%)
Query: 692 PDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCE-- 749
P+PG P ++ Q +S L D+G GS + S + + V+ E
Sbjct: 219 PEPGEP-GPDMAQEAPQEDTSPMALMDKGENELTGSASEESQETTTSTIITTTVITTEQA 277
Query: 750 -APCGGHLTSPSGTILSPGWPGF-YKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLE 807
A C ++P G I S +P + L C + + GY +++ VN E
Sbjct: 278 PALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVK----SVNLSDGE 333
Query: 808 VRDGRTYSAPLIGVYHGTQV---PQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQS 864
+ R P + V + Q + S +N + + F T + FQL Y+ L
Sbjct: 334 LLSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLS- 392
Query: 865 DHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLEC----EPNFQWSRALPSC 920
C P P +G D + G + F C GY L + L C +P+ WS P C
Sbjct: 393 --CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPH--WSSQEPIC 448
Query: 921 EALCGGFIQGSS-GTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLL 979
A CGG + ++ G +LSP +P+ + C W IE G+ + F L HD
Sbjct: 449 SAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLL---HDKDR 505
Query: 980 ITENGSFTQPLRQLTGSRLP--APISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLE 1037
+T + T L S P L T ++ F SD + + FNI F ++
Sbjct: 506 MTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKG 565
Query: 1038 PCEEPEVPAYSIRKG-LQFGVGDTLTFSCFPGYRLE-GTARITCLGGRRRLWSSPLPRCV 1095
C EP + + + +G + F+C PG+ LE G A I C+ R W+ P C
Sbjct: 566 HCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCR 625
Query: 1096 AECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYD 1155
A CG ++ G +LSPN+P Y +CI+ I K I L + LS D+L +YD
Sbjct: 626 AMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYD 685
Query: 1156 GNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAE----NTSKGFELHFSSFEL-IK 1210
G+ +LG + L S++ L + F +D +GF +++
Sbjct: 686 GDEVMPHILGQYL-GNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDS 744
Query: 1211 CEDPGTPKFGYKVHDEGHFA-GSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVA 1269
C D + G+K G+ +++ CDPGY + GS+ L C +W P C
Sbjct: 745 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSDPPFCEK 802
Query: 1270 ECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIW 1329
T GEV H I
Sbjct: 803 IMYCTDPGEVD------------------------------------------HSTRLIS 820
Query: 1330 DGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPG 1389
D + G ++ P + S + T +TS+ + + +C++PG
Sbjct: 821 DPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVS---EESLACDNPG 877
Query: 1390 IPQNGSR--SGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC 1441
+P+NG + + G+S F C G+ L G I C+ + W P C
Sbjct: 878 LPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCI-LGQPSHWNGPLPVC 930
Score = 170 bits (431), Expect = 2e-41
Identities = 173/710 (24%), Positives = 283/710 (39%), Gaps = 76/710 (10%)
Query: 1966 AQCGGTVEEMEGVILSPGFPGNYPSN-MDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEI 2024
A C + EG I S +P +N ++C++ + + G+G +Q + + + + I
Sbjct: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDG-ELLSI 337
Query: 2025 RNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISS 2084
R T ++ + + S ++ +VYF + F+L YQ S +
Sbjct: 338 RGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLS---CN 394
Query: 2085 FLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQS 2144
F R D ++ V DL G A+
Sbjct: 395 FPRRPDSGDVT------------VMDLHSGGVAH-------------------------- 416
Query: 2145 VTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSSN-GTVYSPGFPSPYS 2203
F C GY+L G +LTC + + +W P C PCGG + ++ G V SP +P +
Sbjct: 417 --FHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTN 474
Query: 2204 SSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRL--GVFTRSMAKKTV 2261
SQ C+W I P G + L+ L D +T+ G + L + T S+ + +
Sbjct: 475 GSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTVHSGQTNKSALLYDSLQTESVPFEGL 533
Query: 2262 QSSSNQVLLKFHRD-AATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRY 2320
S N + ++F D A F I F A+ C P I N T + +NIG IV +
Sbjct: 534 LSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYI-QNGNFTTSDPTYNIGTIVEF 592
Query: 2321 RCLPGFTL-VGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQ 2379
C PG +L G I+ C + P+C C L+ GV+LS ++P Y +
Sbjct: 593 TCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGE--LSAVAGVVLSPNWPEPYVE 650
Query: 2380 FQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTS 2439
+ C W + V + I L ++ FL+ D I+DG +L GN S P + S
Sbjct: 651 GEDCIWKIHVGEEKRIFLDIQ-FLNLSNSDILTIYDGDEVMPHILGQYLGN-SGPQKLYS 708
Query: 2440 SSNSVYLRWSSDHA----YNRKGFKIRY----SAPYCS-LPRAPLHGFILGQTSTQPGGS 2490
S+ + +++ SD A +GF + Y CS LP T G
Sbjct: 709 STPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGAR 768
Query: 2491 IHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALS-CGLPEAPKNG--MVFGKEY 2547
I + C+ GY +VG C Q WS P C+ + C P + ++
Sbjct: 769 ITYQCDPGYDIVGSDTLTC----QWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVL 824
Query: 2548 TVGTKAMYSCSEGYHLQAGAEATAECLDTG--LWSNRNVPPQCVPVTCPDVSSISVEHGR 2605
VGT Y+C+ G+ L+ + T +TG +W++R P CV + +
Sbjct: 825 LVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSR--LPHCVSEESLACDNPGLPENG 882
Query: 2606 WRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRI 2655
++++++ Y L +C G+ G+ IRC P C++
Sbjct: 883 YQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCKV 932
Score = 157 bits (398), Expect = 1e-37
Identities = 154/570 (27%), Positives = 244/570 (42%), Gaps = 71/570 (12%)
Query: 26 CTFQLHGPNGTVESPGFPY-GYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSV-- 82
C+ P G ++S +P N+ CT+ +T + ++L +S L D ++LS+
Sbjct: 281 CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLS-DGELLSIRG 339
Query: 83 FDGPPQPENLRTRLTGFQLPATIVSAATTLSL--RLISDYAVSAQGFHATYEVLPSHTCG 140
DGP + T I S T+S+ R D + H +L +C
Sbjct: 340 VDGPTL--TVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML---SCN 394
Query: 141 NPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADD 200
P R +G + G + C+LG+ L+G +LTC S+ W P C A
Sbjct: 395 FPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASK--PHWSSQEPICSA-- 450
Query: 201 ACGGTLRGQS-GIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVT 259
CGG + + G + SP +P + + C WTI A G + L F L D +
Sbjct: 451 PCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTVHS 510
Query: 260 G-TEGSSLWFTG---ASLP-APVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSR 314
G T S+L + S+P ++S N +R+ FTSD F+ +++
Sbjct: 511 GQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFE---------- 560
Query: 315 GVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSD--FRLGSSVQFTCNEG 372
+GH C +P I + G SD + +G+ V+FTC+ G
Sbjct: 561 --------------------AFEKGH--CYEPYI-QNGNFTTSDPTYNIGTIVEFTCDPG 597
Query: 373 YDL-QGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHC 431
+ L QG I C+ V D + W+D P+CRA MC L +G++ SPN+P Y C
Sbjct: 598 HSLEQGPAIIECINVRDPY--WNDTEPLCRA-MCGGELSAVAGVVLSPNWPEPYVEGEDC 654
Query: 432 VWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTN 491
+W I + K I L + +L D LT+ DG D +L G S P + S+
Sbjct: 655 IWKI-HVGEEKRIFLDIQFLNLSNS-DILTIYDG--DEVMPHILGQYLGNSGPQKLYSST 710
Query: 492 HQMWLLFQTDGS----GSSLGFKASYEEIEQG-SCGD-PGIP-AYGRREGSRFHHGDTLK 544
+ + F +D + G GF +Y E+ + SC D P I + + G +
Sbjct: 711 PDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARIT 770
Query: 545 FECQPAFELVGQKAITCQKNNQWSAKKPGC 574
++C P +++VG +TCQ + WS+ P C
Sbjct: 771 YQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 800
Score = 156 bits (394), Expect = 4e-37
Identities = 188/753 (24%), Positives = 304/753 (40%), Gaps = 125/753 (16%)
Query: 197 RADDACGGTLRGQSGIISSPHFPSEYHNN-ADCTWTILAELGDTIALVFIDFQLEDGYDF 255
+A C + G I S +P NN +CT+ + G + L L DG +
Sbjct: 276 QAPALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDG-EL 334
Query: 256 LEVTGTEGSSLWFTGAS---LPAPVISSK-NWLRLHFTSDGNHRQRGFSAQYQVKKQIEL 311
L + G +G +L + VI S N + ++F + + F YQ
Sbjct: 335 LSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQA------ 388
Query: 312 KSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNE 371
M S C P P+ G D G F C+
Sbjct: 389 ------FMLS---------------------CNFPRRPDSGDVTVMDLHSGGVAHFHCHL 421
Query: 372 GYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHC 431
GY+LQG+K +TC+ S WS P+C A A G + SP++P + + C
Sbjct: 422 GYELQGAKMLTCINASKPH--WSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFC 479
Query: 432 VWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLY-ILTGTSVP-DLIVS 489
+W I A K + L FE L D +TV G ++ +LY L SVP + ++S
Sbjct: 480 IWTIEAPEGQK-LHLHFERL-LLHDKDRMTVHSG--QTNKSALLYDSLQTESVPFEGLLS 535
Query: 490 TNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYG-RREGSRFHHGDTLKFECQ 548
+ + + F +D + ++ F +E E+G C +P I ++ G ++F C
Sbjct: 536 EGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCD 595
Query: 549 PAFELV-GQKAITC--QKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCV 605
P L G I C ++ W+ +P C C ++ +GVVLSPN+PE Y C+
Sbjct: 596 PGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCI 655
Query: 606 WLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVAR 665
W I E RI L +++ D L I DG +LG + GN P + SS
Sbjct: 656 WKIHVGEEKRIFLDIQFLNLS-NSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLT 714
Query: 666 LEFQTDHS---TGK-RGFNITF-TTFRHNECPDPGVPVNGKRFGDSLQL--GSSISFLCD 718
++F +D + GK +GF + + R++ C D NG + +L G+ I++ CD
Sbjct: 715 IQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCD 774
Query: 719 EGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSC 778
G+ GS+T+TC + + W+S P F + + C
Sbjct: 775 PGY-DIVGSDTLTC---QWDLSWSSD------------------------PPFCEKIMYC 806
Query: 779 AWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQV-----PQFLIS 833
PG EV++ T R S P++ V GT + P F++
Sbjct: 807 -----TDPG------------EVDHST------RLISDPVLLV--GTTIQYTCNPGFVLE 841
Query: 834 TSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQR--HGNDFYVGALVTF 891
S+ L + ++ + I ++ +S C +PG+P NG + + + G +TF
Sbjct: 842 GSSLLTCY--SRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTF 899
Query: 892 SCDSGYTLSDGEPLEC---EPNFQWSRALPSCE 921
C G+ L + C +P+ W+ LP C+
Sbjct: 900 MCYEGFELMGEVTIRCILGQPS-HWNGPLPVCK 931
Score = 110 bits (275), Expect = 2e-23
Identities = 109/417 (26%), Positives = 174/417 (41%), Gaps = 64/417 (15%)
Query: 35 GTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDGPPQP----- 89
G V SP +P C WTI A E ++ L F+ L D D ++V G
Sbjct: 462 GRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH-DKDRMTVHSGQTNKSALLY 520
Query: 90 ENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRLPNG- 148
++L+T F+ ++S T+ + SD A +A F+ +E C P + NG
Sbjct: 521 DSLQTESVPFE---GLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP-YIQNGN 576
Query: 149 -IQQGSTFNLGDKVRYSCNLGFFLE-GHAVLTCHAGSENSATWDFPLPSCRADDACGGTL 206
T+N+G V ++C+ G LE G A++ C + W+ P CRA CGG L
Sbjct: 577 FTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECI--NVRDPYWNDTEPLCRA--MCGGEL 632
Query: 207 RGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSSL 266
+G++ SP++P Y DC W I +G+ +F+D Q + + +T +G +
Sbjct: 633 SAVAGVVLSPNWPEPYVEGEDCIWKI--HVGEE-KRIFLDIQFLNLSNSDILTIYDGDEV 689
Query: 267 W------FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIEL-KSRGVKLM 319
+ G S P + SS L + F SD G Q + IE+ ++ +
Sbjct: 690 MPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFG-KGQGFIMNYIEVSRNDSCSDL 748
Query: 320 PSKDNSQKTSVLTQV--------GVSQGHNM--------------------------CPD 345
P N KT+ T++ G+++ C D
Sbjct: 749 PEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTD 808
Query: 346 PGIPERGKRLGSD--FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVC 400
PG + RL SD +G+++Q+TCN G+ L+GS +TC W+ P C
Sbjct: 809 PGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHC 865
Score = 93.2 bits (230), Expect = 4e-18
Identities = 135/571 (23%), Positives = 219/571 (38%), Gaps = 70/571 (12%)
Query: 2655 IISCGELPIPPNGHRIGTLSVY-GATAIFSCNSGYTLVGSRVRECM--ANGLWSGSEVRC 2711
++SC P P+ + + ++ G A F C+ GY L G+++ C+ + WS E C
Sbjct: 390 MLSCN-FPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPIC 448
Query: 2712 LAGHCGTPEPIVNGHINGENY--SYRGSV----VYQCNAGFRLIGMSVRICQQDHHWSGK 2765
A G G + +Y + GS + G +L R+ D K
Sbjct: 449 SAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHD-----K 503
Query: 2766 TPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLP 2825
V H G S + DS +V + + GN+ R+ +T
Sbjct: 504 DRMTV-----HSGQTNKSALLYDSLQTESVPFEGLLSE----GNTIRI-----EFTSDQA 549
Query: 2826 HCSGT--------SVGVCGDPGIPAHGIRLGD-SFDPGTVMRFSCEAGHVL-RGSSERTC 2875
+ T G C +P I D +++ GT++ F+C+ GH L +G + C
Sbjct: 550 RAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIEC 609
Query: 2876 --QANGSWSGSQPECGVISCGNPGTPSNARVVFS----DGLVFSSSIVYECREGYYATGL 2929
+ W+ ++P C + CG + A VV S + V +++ G
Sbjct: 610 INVRDPYWNDTEPLCRAM-CGGE-LSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIF 667
Query: 2930 LSRHCSVNGTWTGSDPECLVINCGDPGIP-ANGLRLGNDFRYNKTVTYQCVPGYMMESHR 2988
L S+ + L I GD +P G LGN Y P ++ H
Sbjct: 668 LDIQFL-----NLSNSDILTIYDGDEVMPHILGQYLGNS---GPQKLYSSTPDLTIQFHS 719
Query: 2989 --VSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGS--DFMWGSSVTYACLEGYQL 3044
++ V + C P I NG S + + G+ +TY C GY +
Sbjct: 720 DPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDI 779
Query: 3045 SLPAVFTCEGNGSWTGELPQCFPV-FCGDPGVPSRGRR--EDRGFSYRSSVSFSCHPPLV 3101
TC+ + SW+ + P C + +C DPG R D +++ ++C+P V
Sbjct: 780 VGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFV 839
Query: 3102 LVGSPRRFCQSDGT----WSGTQPSCIDPTLTTCADPGVPQFGIQ-NNSQGYQVGSTVLF 3156
L GS C S T W+ P C+ C +PG+P+ G Q + Y G ++ F
Sbjct: 840 LEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTF 899
Query: 3157 RCQKGYLLQGSTTRTCLPNLT--WSGTPPDC 3185
C +G+ L G T C+ W+G P C
Sbjct: 900 MCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
Score = 82.4 bits (202), Expect = 7e-15
Identities = 51/164 (31%), Positives = 71/164 (43%), Gaps = 11/164 (6%)
Query: 2738 VVYQCNAGFRLIGMSVRICQQDHHWSGKTPFC-VLVSCGHPGSPPHSQ--MSGDSYTVGA 2794
+ YQC+ G+ ++G CQ D WS PFC ++ C PG HS +S VG
Sbjct: 769 ITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGT 828
Query: 2795 VVRYSCIGKRTLVGNSTRMCGL----DGHWTGSLPHCSGTSVGVCGDPGIPAHGIRL--G 2848
++Y+C L G+S C WT LPHC C +PG+P +G ++
Sbjct: 829 TIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYK 888
Query: 2849 DSFDPGTVMRFSCEAGHVLRGSSERTCQAN--GSWSGSQPECGV 2890
+ PG + F C G L G C W+G P C V
Sbjct: 889 RLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCKV 932
Score = 76.3 bits (186), Expect = 5e-13
Identities = 49/166 (29%), Positives = 80/166 (48%), Gaps = 11/166 (6%)
Query: 2854 GTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPEC-GVISCGNPGTPSNARVVFSDG-LV 2911
G + + C+ G+ + GS TCQ + SWS P C ++ C +PG ++ + SD L+
Sbjct: 766 GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL 825
Query: 2912 FSSSIVYECREGYYATG--LLSRHCSVNGT--WTGSDPECL---VINCGDPGIPANGLRL 2964
++I Y C G+ G LL+ + GT WT P C+ + C +PG+P NG ++
Sbjct: 826 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQI 885
Query: 2965 GNDFRY--NKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCK 3008
Y +++T+ C G+ + + WNG PVCK
Sbjct: 886 LYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK 931
Score = 73.6 bits (179), Expect = 3e-12
Identities = 115/499 (23%), Positives = 179/499 (35%), Gaps = 112/499 (22%)
Query: 2835 CGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTC--QANGSWSGSQPECGVIS 2892
C P P G G V F C G+ L+G+ TC + WS +P C
Sbjct: 393 CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA-P 451
Query: 2893 CG------------NPGTPSNA-------------------------------RVVFSDG 2909
CG +P P N R+ G
Sbjct: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTVHSG 511
Query: 2910 LVFSSSIVYEC--REGYYATGLLSRHCSVNGTWTGSDPECLVI-----------NCGDPG 2956
S+++Y+ E GLLS ++ +T +C +P
Sbjct: 512 QTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPY 571
Query: 2957 IPANGLRLGNDFRYN--KTVTYQCVPGYMMESHRVSVLSC--TKDRTWNGTKPVCKALMC 3012
I NG +D YN V + C PG+ +E +++ C +D WN T+P+C+A MC
Sbjct: 572 IQ-NGNFTTSDPTYNIGTIVEFTCDPGHSLEQGP-AIIECINVRDPYWNDTEPLCRA-MC 628
Query: 3013 KPP----------PLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGEL 3062
P P V G D +W V E ++ L F N
Sbjct: 629 GGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVG----EEKRIFLDIQFLNLSNSD----- 679
Query: 3063 PQCFPVFCGDPGVP--------SRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDG 3114
++ GD +P + G ++ + ++ F P ++ G + F +
Sbjct: 680 --ILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYI 737
Query: 3115 TWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQGYQV-GSTVLFRCQKGYLLQGSTTRTCL 3173
S +C+D Q G + S V G+ + ++C GY + GS T TC
Sbjct: 738 EVSRND---------SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQ 788
Query: 3174 PNLTWSGTPPDCVP-HHCRQPETPTHANVGALD-LPSMGYTLIYSCQEGFSLKGGSEHRT 3231
+L+WS PP C +C P H+ D + +G T+ Y+C GF L+ GS T
Sbjct: 789 WDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLE-GSSLLT 847
Query: 3232 CKADGS----WTGKPPICL 3246
C + + WT + P C+
Sbjct: 848 CYSRETGTPIWTSRLPHCV 866
Score = 71.2 bits (173), Expect = 2e-11
Identities = 52/166 (31%), Positives = 71/166 (42%), Gaps = 16/166 (9%)
Query: 3092 VSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQGYQ-V 3150
+++ C P +VGS CQ D +WS P C + C DPG + S V
Sbjct: 769 ITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC--EKIMYCTDPGEVDHSTRLISDPVLLV 826
Query: 3151 GSTVLFRCQKGYLLQGSTTRTCLPNLT----WSGTPPDCVPHH---CRQPETPTHAN--- 3200
G+T+ + C G++L+GS+ TC T W+ P CV C P P +
Sbjct: 827 GTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQIL 886
Query: 3201 VGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGS-WTGKPPIC 3245
L LP G +L + C EGF L G R S W G P+C
Sbjct: 887 YKRLYLP--GESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
Score = 63.9 bits (154), Expect = 3e-09
Identities = 55/200 (27%), Positives = 86/200 (43%), Gaps = 14/200 (7%)
Query: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG 85
C +L G V SP +P Y +C W I E+ RI L Q L D+L+++DG
Sbjct: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-DILTIYDG 686
Query: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYA----VSAQGFHATY-EVLPSHTCG 140
++ + G P + S+ L+++ SD A QGF Y EV + +C
Sbjct: 687 DEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCS 746
Query: 141 NPGRLPNGIQQGSTFNL--GDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRA 198
+ + NG + S L G ++ Y C+ G+ + G LTC + +W P C
Sbjct: 747 DLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTC----QWDLSWSSDPPFCEK 802
Query: 199 DDAC--GGTLRGQSGIISSP 216
C G + + +IS P
Sbjct: 803 IMYCTDPGEVDHSTRLISDP 822
Score = 45.1 bits (105), Expect = 0.001
Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 2/65 (3%)
Query: 139 CGNPGRLPNGIQQGS--TFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
C +PG + + + S +G ++Y+CN GF LEG ++LTC++ + W LP C
Sbjct: 806 CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHC 865
Query: 197 RADDA 201
++++
Sbjct: 866 VSEES 870
Score = 44.7 bits (104), Expect = 0.002
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 1908 SCPEPAVPSNGVKTGER--YLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLC 1964
+C P +P NG + + YL + ++F C G+ L G I C+ G WN P P+C
Sbjct: 872 ACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
Score = 37.7 bits (86), Expect = 0.20
Identities = 17/61 (27%), Positives = 29/61 (47%)
Query: 2294 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEV 2353
C P + N + + G+ + + C GF L+G + C LG + GP P+C+V
Sbjct: 873 CDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCKV 932
Query: 2354 H 2354
+
Sbjct: 933 N 933
Score = 37.0 bits (84), Expect = 0.34
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 9/82 (10%)
Query: 1735 CSSVPEPRYGKRLGSD--FSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC 1792
C+ E + RL SD VG +++ CN G+ L+GS + C W P C
Sbjct: 806 CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHC 865
Query: 1793 VVPCGGNLTERRGTILSPGFPE 1814
V +E +PG PE
Sbjct: 866 V-------SEESLACDNPGLPE 880
Score = 34.3 bits (77), Expect = 2.2
Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 3210 GYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEV 3248
G + Y C G+ + G S+ TC+ D SW+ PP C ++
Sbjct: 766 GARITYQCDPGYDIVG-SDTLTCQWDLSWSSDPPFCEKI 803
>gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3 [Homo
sapiens]
Length = 840
Score = 232 bits (591), Expect = 6e-60
Identities = 158/518 (30%), Positives = 253/518 (48%), Gaps = 21/518 (4%)
Query: 1098 CGNSVTGTQGTLLSPNF--PVNYNNNH-ECIYSIQTQPGKGIQLKARAFELSEGDVLKVY 1154
C N+++ +G + SP+ PV+ +C YSI PG GI+++ + LS+ + L V
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1155 DGNNNSARLLGVFSHSEMMGV--TLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCE 1212
G + + ++S M+G L S ++ L L F + GF +H+ ++ L+ C
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAY-LLSCG 221
Query: 1213 DPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECG 1272
P P G + H G + +F CD GY L+G E L+CL+G R +W+ P+C+A CG
Sbjct: 222 FPPRPAHGDVSVTDLH-PGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 280
Query: 1273 GTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGP 1332
GT+ G+++SP NL C W IEA G + LHF +E +D L + G
Sbjct: 281 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 340
Query: 1333 VESGVLLKELSGPALP-KDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIP 1391
++ + +P + L S S+ ++ ++ + +++F C P +
Sbjct: 341 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 400
Query: 1392 Q-NGSRSGDSWEAGDSTVFQCDPGYALQGSA---EISCVKIENRFFWQPSPPTCIAPCGG 1447
N + + + G F C PGYAL+ I CV W + P C A CGG
Sbjct: 401 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVD-PTEPHWNDTEPACKAMCGG 459
Query: 1448 DLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDS 1507
+L+ P+GV+LSP++P+ Y PG++C W V V + I L I N+ G D L ++DG
Sbjct: 460 ELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGP 518
Query: 1508 LSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSN----AGFVIDYTENPR-ESCFDPG 1562
+ ++ G Q R+ SS L L F++ N GFV+ + E PR ++C +
Sbjct: 519 SARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELP 578
Query: 1563 SIKNGTRVGS--DLKLGSSVTYYCHGGYEVEGTSTLSC 1598
+ G R S DL G+ +TY C GYE+ G+ L+C
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC 616
Score = 202 bits (513), Expect = 6e-51
Identities = 187/722 (25%), Positives = 295/722 (40%), Gaps = 80/722 (11%)
Query: 1278 EVSGQVLSPGYPAPYEHNL---NCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDG--P 1332
E G V SP +P L +C ++I G I + + + ++L + G P
Sbjct: 109 EGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSP 168
Query: 1333 VESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQ 1392
+ LL S + L S N ++L F + GF I + + SC P P
Sbjct: 169 GLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQ-AYLLSCGFPPRPA 227
Query: 1393 NGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGP 1452
+G S G + F CD GY LQG + C+ R W P+C+A CGG +
Sbjct: 228 HGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN-GTRPSWNGETPSCMASCGGTIHNA 286
Query: 1453 S-GVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPL 1511
+ G I+SP P C W + + + L F +L+ D L + G LSP+
Sbjct: 287 TLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPV 346
Query: 1512 IGSFYGSQLPGR-IESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSIK-NGTR 1569
I +P R + S + SL++ S+ + + + + CF P N T
Sbjct: 347 IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTT 406
Query: 1570 VGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDG-KPVWNNPRPVCTAPCGGQYVGSDG 1628
+ + G+ T+ C GY +E + I D +P WN+ P C A CGG+ G
Sbjct: 407 TDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAG 466
Query: 1629 VVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSL 1688
VVLSP++PQ+Y+ GQ C++ V V ++ + Q + D++ + DG +R+L+ L
Sbjct: 467 VVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSARVLAQL 526
Query: 1689 SGSHTGESLPLATSNQVLIKFSAKGLAP----ARGFHFVYQAVPRTSATQCSSVPEPRYG 1744
G L L++ + ++F A P +GF ++ VPR C +P P +G
Sbjct: 527 RGPQPRRRL-LSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT--CPELPPPEWG 583
Query: 1745 KRLGS--DFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC--VVPCG--G 1798
R S D G ++ ++C GY L GS + C W+ + P C ++ C G
Sbjct: 584 WRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPACQKIMTCADPG 639
Query: 1799 NLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADN 1858
+ T GF P G+ +Q + + + +GA
Sbjct: 640 EIANGHRTASDAGF----------------PVGSHVQYRCLPGYS---------LEGA-- 672
Query: 1859 TVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNG 1918
A+L S +SD A L+Y+ C P VP NG
Sbjct: 673 --------------AMLTCYSRDTGTPKWSDRVPKCA---LKYE-----PCLNPGVPENG 710
Query: 1919 VKT--GERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLC-IAQCGGTVEEM 1975
+T Y + + F C G+ L G I+C+PG +W PPLC + Q ++
Sbjct: 711 YQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVTQTTDPSRQL 770
Query: 1976 EG 1977
EG
Sbjct: 771 EG 772
Score = 199 bits (506), Expect = 4e-50
Identities = 190/743 (25%), Positives = 304/743 (40%), Gaps = 81/743 (10%)
Query: 722 LGTQGSE--TITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSP--GWP-GFYKDAL 776
LG +G E T T ++ +V + + C +++ G + SP G P L
Sbjct: 74 LGPEGGEEETTTTIITTTTV---TTTVTSPVLCNNNISEGEGYVESPDLGSPVSRTLGLL 130
Query: 777 SCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYS-AP-LIGVYHGTQVPQFLIST 834
C + I PGY I+I + L + G + AP L+ Q L S
Sbjct: 131 DCTYSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSP 190
Query: 835 SNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCD 894
+N L L F + + GF++ Y+ L C P P +G D + G TF CD
Sbjct: 191 TNRLLLHFQSPRVPRGGGFRIHYQAYLLS---CGFPPRPAHGDVSVTDLHPGGTATFHCD 247
Query: 895 SGYTLSDGEPLECEPNFQ--WSRALPSCEALCGGFIQGSS-GTILSPGFPDFYPNNLNCT 951
SGY L E L C + W+ PSC A CGG I ++ G I+SP NL C
Sbjct: 248 SGYQLQGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCR 307
Query: 952 WIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFT 1011
W+IE + G+ + F L+ +D L++ GS P+ + S + GL +
Sbjct: 308 WVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPV--IYDSDMDDVPERGLISDAQ 365
Query: 1012 A-QVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRK-GLQFGVGDTLTFSCFPGY 1069
+ V +S+ + ++ F ++ + C P + ++ ++ G TFSC PGY
Sbjct: 366 SLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGY 425
Query: 1070 RLEGTA---RITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIY 1126
LE I C+ W+ P C A CG ++ G +LSP++P +Y+ +C++
Sbjct: 426 ALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVW 485
Query: 1127 SIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWL 1186
+ Q K I L+ + EGD+L ++DG+ SAR+L + L S+ L L
Sbjct: 486 GVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRR-RLLSSGPDLTL 544
Query: 1187 DFITDA----ENTSKGFELHFSSF-ELIKCEDPGTPKFGYKVHDEGH-FAGSSVSFSCDP 1240
F +GF LHF C + P++G++ G G+ +++ C+P
Sbjct: 545 QFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEP 604
Query: 1241 GYSLRGSEELLCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIW 1300
GY L GS+ L C WD C + G++ + A
Sbjct: 605 GYELLGSDILTC------QWDLSWSAAPPACQKIMTCADPGEIANGHRTA---------- 648
Query: 1301 TIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVL 1360
++AG +G H V + L G +L +++
Sbjct: 649 ---SDAGFPVGSH-----------------------VQYRCLPGYSLEG------AAMLT 676
Query: 1361 QFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQNGSRS--GDSWEAGDSTVFQCDPGYALQ 1418
+S D T K + C +PG+P+NG ++ ++AG+S F C G+ L
Sbjct: 677 CYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELI 736
Query: 1419 GSAEISCVKIENRFFWQPSPPTC 1441
G I+CV + W PP C
Sbjct: 737 GEVTITCVP-GHPSQWTSQPPLC 758
Score = 176 bits (447), Expect = 3e-43
Identities = 170/633 (26%), Positives = 253/633 (39%), Gaps = 85/633 (13%)
Query: 1619 CGGQYVGSDGVVLSPNY--PQNYTSGQI-CLYFVTVPKDYVVFGQFAFFHTALNDVVEVH 1675
C +G V SP+ P + T G + C Y + V Y + Q + + + + V
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1676 DGHSQHS---RLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSA 1732
G RLL++ S G+ L T N++L+ F + + GF YQA
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPT-NRLLLHFQSPRVPRGGGFRIHYQAY----L 217
Query: 1733 TQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC 1792
C P P +G +D G F C+SGY LQG + CL G WN P+C
Sbjct: 218 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN--GTRPSWNGETPSC 275
Query: 1793 VVPCGGNLTERR-GTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLE 1851
+ CGG + G I+SP +L C W I EG + + +++ D L
Sbjct: 276 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 335
Query: 1852 VFDGADNTVTMLGSFSGTTVPAL-LNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCP 1910
V G ++ VP L S + LY+ S+ + L ++ C
Sbjct: 336 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 395
Query: 1911 EPAVPSNGVKTGE-RYLVNDVVSFQCEPGYALQGHAH---ISCMPGTVRRWNYPPPLCIA 1966
P + V T + Y + +F C PGYAL+ I C+ T WN P C A
Sbjct: 396 APFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKA 455
Query: 1967 QCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQ-------FLNFSTEPNH 2019
CGG + E GV+LSP +P +Y DC W G H+Q +
Sbjct: 456 MCGGELSEPAGVVLSPDWPQSYSPGQDCVW--------GVHVQEEKRILLQVEILNVREG 507
Query: 2020 DYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRP----GFKLEYQD 2075
D + + +G ++R++ + G + LLS+ + T+ F + P GF L +++
Sbjct: 508 DMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKE 567
Query: 2076 L-----------------TYSHQISSFLRGFDLS-------ELERTNSTPPVAASYVWDL 2111
+ T SH +RG L+ EL ++ + WDL
Sbjct: 568 VPRNDTCPELPPPEWGWRTASH--GDLIRGTVLTYQCEPGYELLGSD-----ILTCQWDL 620
Query: 2112 D-----PGCEAYELQECPDPEPFANG--IVRGAGYNVGQSVTFECLPGYQLTGHPVLTC- 2163
P C+ ++ C DP ANG AG+ VG V + CLPGY L G +LTC
Sbjct: 621 SWSAAPPACQ--KIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCY 678
Query: 2164 --QHGTNRNWDHPLPKCEV---PCGGNITSSNG 2191
GT + W +PKC + PC NG
Sbjct: 679 SRDTGTPK-WSDRVPKCALKYEPCLNPGVPENG 710
Score = 176 bits (446), Expect = 4e-43
Identities = 169/712 (23%), Positives = 281/712 (39%), Gaps = 76/712 (10%)
Query: 404 MCDAHLRGPSGIITSPNFPIQYDNNA---HCVWIITALNPSKVIKLAFEEFDLERGYDTL 460
+C+ ++ G + SP+ C + I P I++ + +L + + L
Sbjct: 102 LCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVY-PGYGIEIQVQTLNLSQEEELL 160
Query: 461 TVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGS 520
+ GG G +L + ++ S +++ L FQ+ GF+ Y+ S
Sbjct: 161 VLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-S 219
Query: 521 CGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQ--WSAKKPGCVFSC 578
CG P PA+G + H G T F C ++L G++ + C + W+ + P C+ SC
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASC 279
Query: 579 FFNFTSPS-GVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDG 637
+ + G ++SP G +L C W+I A R+HL F + ++ D L+++ G
Sbjct: 280 GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSG 339
Query: 638 ATAEAPVLGTFSGNQLPS-SITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGV 696
+ +PV+ + +P + S +E ++ ++ F F + C P +
Sbjct: 340 GSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFL 399
Query: 697 PVNGKRFGD-SLQLGSSISFLCDEGF-LGTQGSETITCVLKEGSVVWNSAVLRCEAPCGG 754
D + G+ +F C G+ L G + WN C+A CGG
Sbjct: 400 AHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGG 459
Query: 755 HLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTY 814
L+ P+G +LSP WP Y C W + Q I + + D L + DG
Sbjct: 460 ELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGP 518
Query: 815 SAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIG----FQLRYETITLQSDHCLDP 870
SA ++ G Q + L+S+ L L F + G F L ++ + ++D C +
Sbjct: 519 SARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVP-RNDTCPEL 577
Query: 871 GIPVNGQR---HGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGGF 927
P G R HG D G ++T+ C+ GY L + L C+ + WS A P+C+ +
Sbjct: 578 PPPEWGWRTASHG-DLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIM--- 633
Query: 928 IQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFT 987
T PG E ++G H ++G GS
Sbjct: 634 ------TCADPG---------------EIANG-------HRTASDAGFPV------GSHV 659
Query: 988 QPLRQLTGSRLPAPISAGLYGNFTAQVRF---ISDFSMSYEGFNITFSEYDLEPCEEPEV 1044
Q R L G L Y T ++ + ++ YE PC P V
Sbjct: 660 Q-YRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYE------------PCLNPGV 706
Query: 1045 P--AYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRC 1094
P Y + G++L F C+ G+ L G ITC+ G W+S P C
Sbjct: 707 PENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 758
Score = 168 bits (425), Expect = 1e-40
Identities = 168/715 (23%), Positives = 274/715 (38%), Gaps = 84/715 (11%)
Query: 1968 CGGTVEEMEGVILSP--GFPGNYPSNM-DCSWKIALPVGFGAHIQFLNFSTEPNHDYIEI 2024
C + E EG + SP G P + + DC++ I + G+G IQ + + + +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 2025 RNG--PYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQI 2082
G P R++ S L S ++ ++F S GF++ YQ
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQ-------- 214
Query: 2083 SSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVG 2142
AY L C P A+G V + G
Sbjct: 215 ----------------------------------AY-LLSCGFPPRPAHGDVSVTDLHPG 239
Query: 2143 QSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSSN-GTVYSPGFPSP 2201
+ TF C GYQL G L C +GT +W+ P C CGG I ++ G + SP
Sbjct: 240 GTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGA 299
Query: 2202 YSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSM----A 2257
+ C W+I G + L+ + + D + + G +P ++ M
Sbjct: 300 VGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSP--VIYDSDMDDVPE 357
Query: 2258 KKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDI 2317
+ + + + + A + ++ F A+ +C P L + V T + E+ G +
Sbjct: 358 RGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP-FLAHGNVTTTDPEYRPGAL 416
Query: 2318 VRYRCLPGFTLV---GNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYP 2374
+ CLPG+ L + C T + P C+ C L++ GV+LS +P
Sbjct: 417 ATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGE--LSEPAGVVLSPDWP 474
Query: 2375 GSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAP 2434
SY Q C W V V+ + I L VE L+ ++ D +FDG + +L L G
Sbjct: 475 QSYSPGQDCVWGVHVQEEKRILLQVE-ILNVREGDMLTLFDGDGPSARVLAQLRGPQPRR 533
Query: 2435 LIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPR--------APLHGFILGQTSTQ 2486
++ SS + L++ + G + + +PR P G+
Sbjct: 534 RLL-SSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDL 592
Query: 2487 PGGSI-HFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQ-ALSCGLPEAPKNGMVFG 2544
G++ + C GY L+G + C Q WS A P CQ ++C P NG
Sbjct: 593 IRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPACQKIMTCADPGEIANGHRTA 648
Query: 2545 KE--YTVGTKAMYSCSEGYHLQAGAEATAECLDTGL--WSNRNVPPQCVPVTCPDVSSIS 2600
+ + VG+ Y C GY L+ A T DTG WS+R P+C P ++
Sbjct: 649 SDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDR--VPKCALKYEPCLNPGV 706
Query: 2601 VEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRI 2655
E+G ++ +++ YQ L C G+ G+ I C P C++
Sbjct: 707 PENG-YQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKV 760
Score = 140 bits (354), Expect = 2e-32
Identities = 153/572 (26%), Positives = 237/572 (41%), Gaps = 68/572 (11%)
Query: 26 CTFQLHGPNGTVESP--GFPYGYP-NYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSV 82
C + G VESP G P +CT++I + I++ Q+ L ++ ++L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 83 FDG--PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCG 140
G P L + + S L L S GF Y+ +CG
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-SCG 221
Query: 141 NPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADD 200
P R +G + + G + C+ G+ L+G L C G+ S W+ PSC A
Sbjct: 222 FPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPS--WNGETPSCMA-- 277
Query: 201 ACGGTLRGQS-GIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVT 259
+CGGT+ + G I SP N C W I A G + L F L++ D L V
Sbjct: 278 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 337
Query: 260 GTEGSSLWFTGASLPAPVISSKNWLRLHFTSD-GNHRQRGFSAQYQVKKQIELKSR---G 315
+G S +PVI + SD + +RG + Q +EL S
Sbjct: 338 ---------SGGSPLSPVI---------YDSDMDDVPERGLISDAQ-SLYVELLSETPAN 378
Query: 316 VKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDL 375
L+ + + + ++ G+ DP ++R G+ F+C GY L
Sbjct: 379 PLLLSLRFEAFEEDRCFAPFLAHGNVTTTDP-----------EYRPGALATFSCLPGYAL 427
Query: 376 Q---GSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCV 432
+ I C+ ++ W+D P C+A MC L P+G++ SP++P Y CV
Sbjct: 428 EPPGPPNAIECVDPTE--PHWNDTEPACKA-MCGGELSEPAGVVLSPDWPQSYSPGQDCV 484
Query: 433 WIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNH 492
W + + K I L E ++ G D LT+ DG DG VL L G ++S+
Sbjct: 485 WGV-HVQEEKRILLQVEILNVREG-DMLTLFDG--DGPSARVLAQLRGPQPRRRLLSSGP 540
Query: 493 QMWLLFQT----DGSGSSLGFKASYEEIEQG-SCGDPGIPAYGRREGSRFHHGD-----T 542
+ L FQ G GF ++E+ + +C + P +G R S HGD
Sbjct: 541 DLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTAS---HGDLIRGTV 597
Query: 543 LKFECQPAFELVGQKAITCQKNNQWSAKKPGC 574
L ++C+P +EL+G +TCQ + WSA P C
Sbjct: 598 LTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 629
Score = 138 bits (347), Expect = 1e-31
Identities = 192/840 (22%), Positives = 296/840 (35%), Gaps = 152/840 (18%)
Query: 202 CGGTLRGQSGIISSPHFPSEYHNNA---DCTWTILAELGDTIALVFIDFQLEDGYDFLEV 258
C + G + SP S DCT++I G I + L + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 259 TG----------TEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQ 308
G SS+ G L +P N L LHF S R GF YQ
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPT----NRLLLHFQSPRVPRGGGFRIHYQAYLL 218
Query: 309 IELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFT 368
C P P G +D G + F
Sbjct: 219 ---------------------------------SCGFPPRPAHGDVSVTDLHPGGTATFH 245
Query: 369 CNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNN 428
C+ GY LQG + + C+ + +W+ P C A G I SP N
Sbjct: 246 CDSGYQLQGEETLICLNGTR--PSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPN 303
Query: 429 AHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDL-I 487
C W+I A + + L FE L+ D L V GG V+Y VP+ +
Sbjct: 304 LTCRWVIEAAEGRR-LHLHFERVSLDEDNDRLMVRSGGSP--LSPVIYDSDMDDVPERGL 360
Query: 488 VSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGR--REGSRFHHGDTLKF 545
+S +++ ++ + L +E E+ C P + A+G + G F
Sbjct: 361 ISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFL-AHGNVTTTDPEYRPGALATF 419
Query: 546 ECQPAFELVGQ---KAITCQKNNQ--WSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGN 600
C P + L AI C + W+ +P C C + P+GVVLSP++P+ Y
Sbjct: 420 SCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSP 479
Query: 601 HLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSS 660
CVW + + E RI L ++V + D L + DG A VL G Q + SS
Sbjct: 480 GQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSS 538
Query: 661 GHVARLEFQTDHSTGKRGFNITFTTF-----RHNECPDPGVPVNGKR---FGDSLQLGSS 712
G L+FQ G F R++ CP+ P G R GD ++ G+
Sbjct: 539 GPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIR-GTV 597
Query: 713 ISFLCDEGFLGTQGSETITCVLKEGSVVWNSA------VLRCEAPCGGHLTSPSGTILSP 766
+++ C+ G+ GS+ +TC + + W++A ++ C P G + + T
Sbjct: 598 LTYQCEPGY-ELLGSDILTC---QWDLSWSAAPPACQKIMTCADP--GEIANGHRTASDA 651
Query: 767 GWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVY-HGT 825
G+P C PGY ++ A ++ Y T
Sbjct: 652 GFPVGSHVQYRCL------PGYSLE-----------------------GAAMLTCYSRDT 682
Query: 826 QVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQR--HGNDF 883
P++ SD R L+ + CL+PG+P NG + + + +
Sbjct: 683 GTPKW------------------SD-----RVPKCALKYEPCLNPGVPENGYQTLYKHHY 719
Query: 884 YVGALVTFSCDSGYTLSDGEPLECEPNF--QWSRALPSCEALCGGFIQGSSGTILSPGFP 941
G + F C G+ L + C P QW+ P C+ Q + + G
Sbjct: 720 QAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKV-----TQTTDPSRQLEGGN 774
Query: 942 DFYPNNLNCTWIIETSHGKGVFFT----FHTFHLESGHDYLLITENGSFTQPLRQLTGSR 997
L +I G +++T F H Y IT F+ PL + +R
Sbjct: 775 LALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGSHSYSPITVESDFSNPLYEAGDTR 834
Score = 118 bits (295), Expect = 1e-25
Identities = 159/627 (25%), Positives = 226/627 (36%), Gaps = 88/627 (14%)
Query: 2655 IISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGL---WSGSEVRC 2711
++SCG P P +G T G TA F C+SGY L G C+ NG W+G C
Sbjct: 217 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSC 275
Query: 2712 LAGHCGT-----------PEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDH 2760
+A GT PEP G G N + R V + G RL R+ +
Sbjct: 276 MASCGGTIHNATLGRIVSPEP---GGAVGPNLTCRW--VIEAAEGRRLHLHFERVSLDED 330
Query: 2761 H-----WSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCG 2815
+ SG +P ++ P + D+ ++ + L+
Sbjct: 331 NDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFE 390
Query: 2816 LDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLR-----GS 2870
D + L H + T+ DP + PG + FSC G+ L +
Sbjct: 391 EDRCFAPFLAHGNVTTT----DP-----------EYRPGALATFSCLPGYALEPPGPPNA 435
Query: 2871 SERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATG-- 2928
E W+ ++P C + G P A VV S S S +C G +
Sbjct: 436 IECVDPTEPHWNDTEPACKAMCGGELSEP--AGVVLSPDWPQSYSPGQDCVWGVHVQEEK 493
Query: 2929 --------LLSRHCSVNGTWTGSDPECLVI-NCGDPGIPANGLRLGNDFRYNKTVTYQCV 2979
L R + + G P V+ P L G D T+ +Q
Sbjct: 494 RILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDL----TLQFQAP 549
Query: 2980 PGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSSVTYACL 3039
PG + K+ N T P PPP D + G+ +TY C
Sbjct: 550 PGPPNPGLGQGFVLHFKEVPRNDTCPEL------PPPEWGWRTASHGDLIRGTVLTYQCE 603
Query: 3040 EGYQLSLPAVFTCEGNGSWTGELPQCFPVF-CGDPGVPSRGRR--EDRGFSYRSSVSFSC 3096
GY+L + TC+ + SW+ P C + C DPG + G R D GF S V + C
Sbjct: 604 PGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRC 663
Query: 3097 HPPLVLVGSPRRFCQSDGT----WSGTQPSCIDPTLTTCADPGVPQFGIQN-NSQGYQVG 3151
P L G+ C S T WS P C C +PGVP+ G Q YQ G
Sbjct: 664 LPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCA-LKYEPCLNPGVPENGYQTLYKHHYQAG 722
Query: 3152 STVLFRCQKGYLLQGSTTRTCLPN--LTWSGTPPDCVPHHCRQPETPTHAN--------- 3200
++ F C +G+ L G T TC+P W+ PP C P
Sbjct: 723 ESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVTQTTDPSRQLEGGNLALAILLP 782
Query: 3201 VGALDLPSMGYTLIYSCQEGFSLKGGS 3227
+G + + G + Y+ +G SL G S
Sbjct: 783 LGLVIVLGSGVYIYYTKLQGKSLFGFS 809
Score = 102 bits (253), Expect = 9e-21
Identities = 139/573 (24%), Positives = 200/573 (34%), Gaps = 129/573 (22%)
Query: 2771 LVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMC--GLDGHWTGSLPHCS 2828
L+SCG P P H +S G + C L G T +C G W G P C
Sbjct: 217 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Query: 2829 GTSVGVCGDPGIPAHGIRLGD--SFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQP 2886
+ G H LG S +PG + + V+ + R +
Sbjct: 277 ASCGGTI-------HNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDE 329
Query: 2887 ECGVISCGNPGTPSNARVVFSD-------GLVFSSSIVYECREGYYATGLLSRHCSVNGT 2939
+ + + G+P + + SD GL+ + +Y LLS
Sbjct: 330 DNDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLY--------VELLSE------- 374
Query: 2940 WTGSDPECLVIN--------CGDPGIP-ANGLRLGNDFRYNKTVTYQCVPGYMMESHRV- 2989
T ++P L + C P + N ++R T+ C+PGY +E
Sbjct: 375 -TPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPP 433
Query: 2990 SVLSCTK--DRTWNGTKPVCKAL----MCKPPPLI-----PNGKVVGSDFMWGSSVTYA- 3037
+ + C + WN T+P CKA+ + +P ++ P G D +WG V
Sbjct: 434 NAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEK 493
Query: 3038 ----------CLEGYQLSLPAVFTCEGNGSWTGEL----------------PQCFPVFCG 3071
EG L+L +G+G L P F
Sbjct: 494 RILLQVEILNVREGDMLTL-----FDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQA 548
Query: 3072 DPGVPSRG----------------------------RREDRGFSYRSSV-SFSCHPPLVL 3102
PG P+ G R G R +V ++ C P L
Sbjct: 549 PPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYEL 608
Query: 3103 VGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQ-GYQVGSTVLFRCQKG 3161
+GS CQ D +WS P+C + TCADPG G + S G+ VGS V +RC G
Sbjct: 609 LGSDILTCQWDLSWSAAPPAC--QKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPG 666
Query: 3162 YLLQGSTTRTCLPNLT----WSGTPPDCVPHH--CRQPETPTHANVGALDLP-SMGYTLI 3214
Y L+G+ TC T WS P C + C P P + G +L
Sbjct: 667 YSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLR 726
Query: 3215 YSCQEGFSLKGGSEHRTCKAD--GSWTGKPPIC 3245
+ C EGF L G TC WT +PP+C
Sbjct: 727 FFCYEGFELIG-EVTITCVPGHPSQWTSQPPLC 758
Score = 99.0 bits (245), Expect = 7e-20
Identities = 100/396 (25%), Positives = 156/396 (39%), Gaps = 17/396 (4%)
Query: 2180 VPCGGNITSSNGTVYSPGFPSPYSSSQ---DCVWLITVPIGHGVRLNLSLLQTEPSGDFI 2236
V C NI+ G V SP SP S + DC + I V G+G+ + + L + +
Sbjct: 101 VLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELL 160
Query: 2237 TI-WDGPQQTAPRLGVFTRSMAK-KTVQSSSNQVLLKFHRD-AATGGIFAIAFSAYPLTK 2293
+ G APRL + + + + ++S +N++LL F GG F I + AY L+
Sbjct: 161 VLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLSC 220
Query: 2294 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEV 2353
PP VT + + G + C G+ L G E L C GT + G P C
Sbjct: 221 GFPPRPAHGDVSVT---DLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMA 277
Query: 2354 HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEI 2413
C + + G I+S G+ TC W++ + L E ++ D +
Sbjct: 278 SC-GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMV 336
Query: 2414 FDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA---PYCSL 2470
G S SP++ + + S + S+Y+ S+ N +R+ A C
Sbjct: 337 RSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFA 396
Query: 2471 PRAPLHGFILGQTSTQPGGSIHFGCNAGYRL--VGHSMAICTRHPQGYHLWSEAIPLCQA 2528
P +PG F C GY L G AI P H W++ P C+A
Sbjct: 397 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPH-WNDTEPACKA 455
Query: 2529 LSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQ 2564
+ CG + G+V ++ C G H+Q
Sbjct: 456 M-CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQ 490
Score = 60.8 bits (146), Expect = 2e-08
Identities = 57/215 (26%), Positives = 89/215 (41%), Gaps = 20/215 (9%)
Query: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG 85
C +L P G V SP +P Y +C W + +E+ RI L + + E D+L++FDG
Sbjct: 457 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDG 515
Query: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVS----AQGFHATYEVLP-SHTCG 140
+ +L G Q ++S+ L+L+ + QGF ++ +P + TC
Sbjct: 516 DGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTC- 574
Query: 141 NPGRLPNGIQQGSTFNLGDKVR-----YSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
LP T + GD +R Y C G+ L G +LTC + +W P+
Sbjct: 575 --PELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPA 628
Query: 196 CRADDACG--GTLRGQSGIISSPHFPSEYHNNADC 228
C+ C G + S FP H C
Sbjct: 629 CQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRC 663
Score = 47.4 bits (111), Expect = 3e-04
Identities = 49/159 (30%), Positives = 63/159 (39%), Gaps = 19/159 (11%)
Query: 2750 GMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGN 2809
G + I Q + S + VL G PG P + G V+R S + L
Sbjct: 141 GYGIEIQVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLR-SPTNRLLLHFQ 199
Query: 2810 STRMC---GLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHV 2866
S R+ G H+ L C G P PAHG PG F C++G+
Sbjct: 200 SPRVPRGGGFRIHYQAYLLSC--------GFPPRPAHGDVSVTDLHPGGTATFHCDSGYQ 251
Query: 2867 LRGSSERTCQANG---SWSGSQPECGVISCGNPGTPSNA 2902
L+G C NG SW+G P C + SCG GT NA
Sbjct: 252 LQGEETLIC-LNGTRPSWNGETPSC-MASCG--GTIHNA 286
Score = 38.5 bits (88), Expect = 0.12
Identities = 18/64 (28%), Positives = 28/64 (43%)
Query: 2946 ECLVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKP 3005
+ +++CG P PA+G D T T+ C GY ++ + +WNG P
Sbjct: 214 QAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETP 273
Query: 3006 VCKA 3009
C A
Sbjct: 274 SCMA 277
>gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 [Homo
sapiens]
Length = 910
Score = 232 bits (591), Expect = 6e-60
Identities = 158/518 (30%), Positives = 253/518 (48%), Gaps = 21/518 (4%)
Query: 1098 CGNSVTGTQGTLLSPNF--PVNYNNNH-ECIYSIQTQPGKGIQLKARAFELSEGDVLKVY 1154
C N+++ +G + SP+ PV+ +C YSI PG GI+++ + LS+ + L V
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 1155 DGNNNSARLLGVFSHSEMMGV--TLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCE 1212
G + + ++S M+G L S ++ L L F + GF +H+ ++ L+ C
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAY-LLSCG 291
Query: 1213 DPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECG 1272
P P G + H G + +F CD GY L+G E L+CL+G R +W+ P+C+A CG
Sbjct: 292 FPPRPAHGDVSVTDLH-PGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 350
Query: 1273 GTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGP 1332
GT+ G+++SP NL C W IEA G + LHF +E +D L + G
Sbjct: 351 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 410
Query: 1333 VESGVLLKELSGPALP-KDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIP 1391
++ + +P + L S S+ ++ ++ + +++F C P +
Sbjct: 411 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 470
Query: 1392 Q-NGSRSGDSWEAGDSTVFQCDPGYALQGSA---EISCVKIENRFFWQPSPPTCIAPCGG 1447
N + + + G F C PGYAL+ I CV W + P C A CGG
Sbjct: 471 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVD-PTEPHWNDTEPACKAMCGG 529
Query: 1448 DLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDS 1507
+L+ P+GV+LSP++P+ Y PG++C W V V + I L I N+ G D L ++DG
Sbjct: 530 ELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGP 588
Query: 1508 LSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSN----AGFVIDYTENPR-ESCFDPG 1562
+ ++ G Q R+ SS L L F++ N GFV+ + E PR ++C +
Sbjct: 589 SARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELP 648
Query: 1563 SIKNGTRVGS--DLKLGSSVTYYCHGGYEVEGTSTLSC 1598
+ G R S DL G+ +TY C GYE+ G+ L+C
Sbjct: 649 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC 686
Score = 202 bits (513), Expect = 6e-51
Identities = 187/722 (25%), Positives = 295/722 (40%), Gaps = 80/722 (11%)
Query: 1278 EVSGQVLSPGYPAPYEHNL---NCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDG--P 1332
E G V SP +P L +C ++I G I + + + ++L + G P
Sbjct: 179 EGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSP 238
Query: 1333 VESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQ 1392
+ LL S + L S N ++L F + GF I + + SC P P
Sbjct: 239 GLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQ-AYLLSCGFPPRPA 297
Query: 1393 NGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGP 1452
+G S G + F CD GY LQG + C+ R W P+C+A CGG +
Sbjct: 298 HGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN-GTRPSWNGETPSCMASCGGTIHNA 356
Query: 1453 S-GVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPL 1511
+ G I+SP P C W + + + L F +L+ D L + G LSP+
Sbjct: 357 TLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPV 416
Query: 1512 IGSFYGSQLPGR-IESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSIK-NGTR 1569
I +P R + S + SL++ S+ + + + + CF P N T
Sbjct: 417 IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTT 476
Query: 1570 VGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDG-KPVWNNPRPVCTAPCGGQYVGSDG 1628
+ + G+ T+ C GY +E + I D +P WN+ P C A CGG+ G
Sbjct: 477 TDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAG 536
Query: 1629 VVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSL 1688
VVLSP++PQ+Y+ GQ C++ V V ++ + Q + D++ + DG +R+L+ L
Sbjct: 537 VVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSARVLAQL 596
Query: 1689 SGSHTGESLPLATSNQVLIKFSAKGLAP----ARGFHFVYQAVPRTSATQCSSVPEPRYG 1744
G L L++ + ++F A P +GF ++ VPR C +P P +G
Sbjct: 597 RGPQPRRRL-LSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT--CPELPPPEWG 653
Query: 1745 KRLGS--DFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC--VVPCG--G 1798
R S D G ++ ++C GY L GS + C W+ + P C ++ C G
Sbjct: 654 WRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPACQKIMTCADPG 709
Query: 1799 NLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADN 1858
+ T GF P G+ +Q + + + +GA
Sbjct: 710 EIANGHRTASDAGF----------------PVGSHVQYRCLPGYS---------LEGA-- 742
Query: 1859 TVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNG 1918
A+L S +SD A L+Y+ C P VP NG
Sbjct: 743 --------------AMLTCYSRDTGTPKWSDRVPKCA---LKYE-----PCLNPGVPENG 780
Query: 1919 VKT--GERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLC-IAQCGGTVEEM 1975
+T Y + + F C G+ L G I+C+PG +W PPLC + Q ++
Sbjct: 781 YQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVTQTTDPSRQL 840
Query: 1976 EG 1977
EG
Sbjct: 841 EG 842
Score = 199 bits (506), Expect = 4e-50
Identities = 190/743 (25%), Positives = 304/743 (40%), Gaps = 81/743 (10%)
Query: 722 LGTQGSE--TITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSP--GWP-GFYKDAL 776
LG +G E T T ++ +V + + C +++ G + SP G P L
Sbjct: 144 LGPEGGEEETTTTIITTTTV---TTTVTSPVLCNNNISEGEGYVESPDLGSPVSRTLGLL 200
Query: 777 SCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYS-AP-LIGVYHGTQVPQFLIST 834
C + I PGY I+I + L + G + AP L+ Q L S
Sbjct: 201 DCTYSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSP 260
Query: 835 SNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCD 894
+N L L F + + GF++ Y+ L C P P +G D + G TF CD
Sbjct: 261 TNRLLLHFQSPRVPRGGGFRIHYQAYLLS---CGFPPRPAHGDVSVTDLHPGGTATFHCD 317
Query: 895 SGYTLSDGEPLECEPNFQ--WSRALPSCEALCGGFIQGSS-GTILSPGFPDFYPNNLNCT 951
SGY L E L C + W+ PSC A CGG I ++ G I+SP NL C
Sbjct: 318 SGYQLQGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCR 377
Query: 952 WIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFT 1011
W+IE + G+ + F L+ +D L++ GS P+ + S + GL +
Sbjct: 378 WVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPV--IYDSDMDDVPERGLISDAQ 435
Query: 1012 A-QVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRK-GLQFGVGDTLTFSCFPGY 1069
+ V +S+ + ++ F ++ + C P + ++ ++ G TFSC PGY
Sbjct: 436 SLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGY 495
Query: 1070 RLEGTA---RITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIY 1126
LE I C+ W+ P C A CG ++ G +LSP++P +Y+ +C++
Sbjct: 496 ALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVW 555
Query: 1127 SIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWL 1186
+ Q K I L+ + EGD+L ++DG+ SAR+L + L S+ L L
Sbjct: 556 GVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRR-RLLSSGPDLTL 614
Query: 1187 DFITDA----ENTSKGFELHFSSF-ELIKCEDPGTPKFGYKVHDEGH-FAGSSVSFSCDP 1240
F +GF LHF C + P++G++ G G+ +++ C+P
Sbjct: 615 QFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEP 674
Query: 1241 GYSLRGSEELLCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIW 1300
GY L GS+ L C WD C + G++ + A
Sbjct: 675 GYELLGSDILTC------QWDLSWSAAPPACQKIMTCADPGEIANGHRTA---------- 718
Query: 1301 TIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVL 1360
++AG +G H V + L G +L +++
Sbjct: 719 ---SDAGFPVGSH-----------------------VQYRCLPGYSLEG------AAMLT 746
Query: 1361 QFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQNGSRS--GDSWEAGDSTVFQCDPGYALQ 1418
+S D T K + C +PG+P+NG ++ ++AG+S F C G+ L
Sbjct: 747 CYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELI 806
Query: 1419 GSAEISCVKIENRFFWQPSPPTC 1441
G I+CV + W PP C
Sbjct: 807 GEVTITCVP-GHPSQWTSQPPLC 828
Score = 176 bits (447), Expect = 3e-43
Identities = 170/633 (26%), Positives = 253/633 (39%), Gaps = 85/633 (13%)
Query: 1619 CGGQYVGSDGVVLSPNY--PQNYTSGQI-CLYFVTVPKDYVVFGQFAFFHTALNDVVEVH 1675
C +G V SP+ P + T G + C Y + V Y + Q + + + + V
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 1676 DGHSQHS---RLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSA 1732
G RLL++ S G+ L T N++L+ F + + GF YQA
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPT-NRLLLHFQSPRVPRGGGFRIHYQAY----L 287
Query: 1733 TQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC 1792
C P P +G +D G F C+SGY LQG + CL G WN P+C
Sbjct: 288 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN--GTRPSWNGETPSC 345
Query: 1793 VVPCGGNLTERR-GTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLE 1851
+ CGG + G I+SP +L C W I EG + + +++ D L
Sbjct: 346 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 405
Query: 1852 VFDGADNTVTMLGSFSGTTVPAL-LNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCP 1910
V G ++ VP L S + LY+ S+ + L ++ C
Sbjct: 406 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 465
Query: 1911 EPAVPSNGVKTGE-RYLVNDVVSFQCEPGYALQGHAH---ISCMPGTVRRWNYPPPLCIA 1966
P + V T + Y + +F C PGYAL+ I C+ T WN P C A
Sbjct: 466 APFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKA 525
Query: 1967 QCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQ-------FLNFSTEPNH 2019
CGG + E GV+LSP +P +Y DC W G H+Q +
Sbjct: 526 MCGGELSEPAGVVLSPDWPQSYSPGQDCVW--------GVHVQEEKRILLQVEILNVREG 577
Query: 2020 DYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRP----GFKLEYQD 2075
D + + +G ++R++ + G + LLS+ + T+ F + P GF L +++
Sbjct: 578 DMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKE 637
Query: 2076 L-----------------TYSHQISSFLRGFDLS-------ELERTNSTPPVAASYVWDL 2111
+ T SH +RG L+ EL ++ + WDL
Sbjct: 638 VPRNDTCPELPPPEWGWRTASH--GDLIRGTVLTYQCEPGYELLGSD-----ILTCQWDL 690
Query: 2112 D-----PGCEAYELQECPDPEPFANG--IVRGAGYNVGQSVTFECLPGYQLTGHPVLTC- 2163
P C+ ++ C DP ANG AG+ VG V + CLPGY L G +LTC
Sbjct: 691 SWSAAPPACQ--KIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCY 748
Query: 2164 --QHGTNRNWDHPLPKCEV---PCGGNITSSNG 2191
GT + W +PKC + PC NG
Sbjct: 749 SRDTGTPK-WSDRVPKCALKYEPCLNPGVPENG 780
Score = 176 bits (446), Expect = 4e-43
Identities = 169/712 (23%), Positives = 281/712 (39%), Gaps = 76/712 (10%)
Query: 404 MCDAHLRGPSGIITSPNFPIQYDNNA---HCVWIITALNPSKVIKLAFEEFDLERGYDTL 460
+C+ ++ G + SP+ C + I P I++ + +L + + L
Sbjct: 172 LCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVY-PGYGIEIQVQTLNLSQEEELL 230
Query: 461 TVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGS 520
+ GG G +L + ++ S +++ L FQ+ GF+ Y+ S
Sbjct: 231 VLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-S 289
Query: 521 CGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQ--WSAKKPGCVFSC 578
CG P PA+G + H G T F C ++L G++ + C + W+ + P C+ SC
Sbjct: 290 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASC 349
Query: 579 FFNFTSPS-GVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDG 637
+ + G ++SP G +L C W+I A R+HL F + ++ D L+++ G
Sbjct: 350 GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSG 409
Query: 638 ATAEAPVLGTFSGNQLPS-SITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGV 696
+ +PV+ + +P + S +E ++ ++ F F + C P +
Sbjct: 410 GSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFL 469
Query: 697 PVNGKRFGD-SLQLGSSISFLCDEGF-LGTQGSETITCVLKEGSVVWNSAVLRCEAPCGG 754
D + G+ +F C G+ L G + WN C+A CGG
Sbjct: 470 AHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGG 529
Query: 755 HLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTY 814
L+ P+G +LSP WP Y C W + Q I + + D L + DG
Sbjct: 530 ELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGP 588
Query: 815 SAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIG----FQLRYETITLQSDHCLDP 870
SA ++ G Q + L+S+ L L F + G F L ++ + ++D C +
Sbjct: 589 SARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVP-RNDTCPEL 647
Query: 871 GIPVNGQR---HGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGGF 927
P G R HG D G ++T+ C+ GY L + L C+ + WS A P+C+ +
Sbjct: 648 PPPEWGWRTASHG-DLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIM--- 703
Query: 928 IQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFT 987
T PG E ++G H ++G GS
Sbjct: 704 ------TCADPG---------------EIANG-------HRTASDAGFPV------GSHV 729
Query: 988 QPLRQLTGSRLPAPISAGLYGNFTAQVRF---ISDFSMSYEGFNITFSEYDLEPCEEPEV 1044
Q R L G L Y T ++ + ++ YE PC P V
Sbjct: 730 Q-YRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYE------------PCLNPGV 776
Query: 1045 P--AYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRC 1094
P Y + G++L F C+ G+ L G ITC+ G W+S P C
Sbjct: 777 PENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 828
Score = 168 bits (425), Expect = 1e-40
Identities = 168/715 (23%), Positives = 274/715 (38%), Gaps = 84/715 (11%)
Query: 1968 CGGTVEEMEGVILSP--GFPGNYPSNM-DCSWKIALPVGFGAHIQFLNFSTEPNHDYIEI 2024
C + E EG + SP G P + + DC++ I + G+G IQ + + + +
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 2025 RNG--PYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQI 2082
G P R++ S L S ++ ++F S GF++ YQ
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQ-------- 284
Query: 2083 SSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVG 2142
AY L C P A+G V + G
Sbjct: 285 ----------------------------------AY-LLSCGFPPRPAHGDVSVTDLHPG 309
Query: 2143 QSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSSN-GTVYSPGFPSP 2201
+ TF C GYQL G L C +GT +W+ P C CGG I ++ G + SP
Sbjct: 310 GTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGA 369
Query: 2202 YSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSM----A 2257
+ C W+I G + L+ + + D + + G +P ++ M
Sbjct: 370 VGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSP--VIYDSDMDDVPE 427
Query: 2258 KKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDI 2317
+ + + + + A + ++ F A+ +C P L + V T + E+ G +
Sbjct: 428 RGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP-FLAHGNVTTTDPEYRPGAL 486
Query: 2318 VRYRCLPGFTLV---GNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYP 2374
+ CLPG+ L + C T + P C+ C L++ GV+LS +P
Sbjct: 487 ATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGE--LSEPAGVVLSPDWP 544
Query: 2375 GSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAP 2434
SY Q C W V V+ + I L VE L+ ++ D +FDG + +L L G
Sbjct: 545 QSYSPGQDCVWGVHVQEEKRILLQVE-ILNVREGDMLTLFDGDGPSARVLAQLRGPQPRR 603
Query: 2435 LIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPR--------APLHGFILGQTSTQ 2486
++ SS + L++ + G + + +PR P G+
Sbjct: 604 RLL-SSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDL 662
Query: 2487 PGGSI-HFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQ-ALSCGLPEAPKNGMVFG 2544
G++ + C GY L+G + C Q WS A P CQ ++C P NG
Sbjct: 663 IRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPACQKIMTCADPGEIANGHRTA 718
Query: 2545 KE--YTVGTKAMYSCSEGYHLQAGAEATAECLDTGL--WSNRNVPPQCVPVTCPDVSSIS 2600
+ + VG+ Y C GY L+ A T DTG WS+R P+C P ++
Sbjct: 719 SDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDR--VPKCALKYEPCLNPGV 776
Query: 2601 VEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRI 2655
E+G ++ +++ YQ L C G+ G+ I C P C++
Sbjct: 777 PENG-YQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKV 830
Score = 140 bits (354), Expect = 2e-32
Identities = 153/572 (26%), Positives = 237/572 (41%), Gaps = 68/572 (11%)
Query: 26 CTFQLHGPNGTVESP--GFPYGYP-NYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSV 82
C + G VESP G P +CT++I + I++ Q+ L ++ ++L +
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 83 FDG--PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCG 140
G P L + + S L L S GF Y+ +CG
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-SCG 291
Query: 141 NPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADD 200
P R +G + + G + C+ G+ L+G L C G+ S W+ PSC A
Sbjct: 292 FPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPS--WNGETPSCMA-- 347
Query: 201 ACGGTLRGQS-GIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVT 259
+CGGT+ + G I SP N C W I A G + L F L++ D L V
Sbjct: 348 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 407
Query: 260 GTEGSSLWFTGASLPAPVISSKNWLRLHFTSD-GNHRQRGFSAQYQVKKQIELKSR---G 315
+G S +PVI + SD + +RG + Q +EL S
Sbjct: 408 ---------SGGSPLSPVI---------YDSDMDDVPERGLISDAQ-SLYVELLSETPAN 448
Query: 316 VKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDL 375
L+ + + + ++ G+ DP ++R G+ F+C GY L
Sbjct: 449 PLLLSLRFEAFEEDRCFAPFLAHGNVTTTDP-----------EYRPGALATFSCLPGYAL 497
Query: 376 Q---GSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCV 432
+ I C+ ++ W+D P C+A MC L P+G++ SP++P Y CV
Sbjct: 498 EPPGPPNAIECVDPTE--PHWNDTEPACKA-MCGGELSEPAGVVLSPDWPQSYSPGQDCV 554
Query: 433 WIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNH 492
W + + K I L E ++ G D LT+ DG DG VL L G ++S+
Sbjct: 555 WGV-HVQEEKRILLQVEILNVREG-DMLTLFDG--DGPSARVLAQLRGPQPRRRLLSSGP 610
Query: 493 QMWLLFQT----DGSGSSLGFKASYEEIEQG-SCGDPGIPAYGRREGSRFHHGD-----T 542
+ L FQ G GF ++E+ + +C + P +G R S HGD
Sbjct: 611 DLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTAS---HGDLIRGTV 667
Query: 543 LKFECQPAFELVGQKAITCQKNNQWSAKKPGC 574
L ++C+P +EL+G +TCQ + WSA P C
Sbjct: 668 LTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 699
Score = 138 bits (347), Expect = 1e-31
Identities = 192/840 (22%), Positives = 296/840 (35%), Gaps = 152/840 (18%)
Query: 202 CGGTLRGQSGIISSPHFPSEYHNNA---DCTWTILAELGDTIALVFIDFQLEDGYDFLEV 258
C + G + SP S DCT++I G I + L + L +
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 259 TG----------TEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQ 308
G SS+ G L +P N L LHF S R GF YQ
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPT----NRLLLHFQSPRVPRGGGFRIHYQAYLL 288
Query: 309 IELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFT 368
C P P G +D G + F
Sbjct: 289 ---------------------------------SCGFPPRPAHGDVSVTDLHPGGTATFH 315
Query: 369 CNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNN 428
C+ GY LQG + + C+ + +W+ P C A G I SP N
Sbjct: 316 CDSGYQLQGEETLICLNGTR--PSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPN 373
Query: 429 AHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDL-I 487
C W+I A + + L FE L+ D L V GG V+Y VP+ +
Sbjct: 374 LTCRWVIEAAEGRR-LHLHFERVSLDEDNDRLMVRSGGSP--LSPVIYDSDMDDVPERGL 430
Query: 488 VSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGR--REGSRFHHGDTLKF 545
+S +++ ++ + L +E E+ C P + A+G + G F
Sbjct: 431 ISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFL-AHGNVTTTDPEYRPGALATF 489
Query: 546 ECQPAFELVGQ---KAITCQKNNQ--WSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGN 600
C P + L AI C + W+ +P C C + P+GVVLSP++P+ Y
Sbjct: 490 SCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSP 549
Query: 601 HLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSS 660
CVW + + E RI L ++V + D L + DG A VL G Q + SS
Sbjct: 550 GQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSS 608
Query: 661 GHVARLEFQTDHSTGKRGFNITFTTF-----RHNECPDPGVPVNGKR---FGDSLQLGSS 712
G L+FQ G F R++ CP+ P G R GD ++ G+
Sbjct: 609 GPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIR-GTV 667
Query: 713 ISFLCDEGFLGTQGSETITCVLKEGSVVWNSA------VLRCEAPCGGHLTSPSGTILSP 766
+++ C+ G+ GS+ +TC + + W++A ++ C P G + + T
Sbjct: 668 LTYQCEPGY-ELLGSDILTC---QWDLSWSAAPPACQKIMTCADP--GEIANGHRTASDA 721
Query: 767 GWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVY-HGT 825
G+P C PGY ++ A ++ Y T
Sbjct: 722 GFPVGSHVQYRCL------PGYSLE-----------------------GAAMLTCYSRDT 752
Query: 826 QVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQR--HGNDF 883
P++ SD R L+ + CL+PG+P NG + + + +
Sbjct: 753 GTPKW------------------SD-----RVPKCALKYEPCLNPGVPENGYQTLYKHHY 789
Query: 884 YVGALVTFSCDSGYTLSDGEPLECEPNF--QWSRALPSCEALCGGFIQGSSGTILSPGFP 941
G + F C G+ L + C P QW+ P C+ Q + + G
Sbjct: 790 QAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKV-----TQTTDPSRQLEGGN 844
Query: 942 DFYPNNLNCTWIIETSHGKGVFFT----FHTFHLESGHDYLLITENGSFTQPLRQLTGSR 997
L +I G +++T F H Y IT F+ PL + +R
Sbjct: 845 LALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGSHSYSPITVESDFSNPLYEAGDTR 904
Score = 118 bits (295), Expect = 1e-25
Identities = 159/627 (25%), Positives = 226/627 (36%), Gaps = 88/627 (14%)
Query: 2655 IISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGL---WSGSEVRC 2711
++SCG P P +G T G TA F C+SGY L G C+ NG W+G C
Sbjct: 287 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSC 345
Query: 2712 LAGHCGT-----------PEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDH 2760
+A GT PEP G G N + R V + G RL R+ +
Sbjct: 346 MASCGGTIHNATLGRIVSPEP---GGAVGPNLTCRW--VIEAAEGRRLHLHFERVSLDED 400
Query: 2761 H-----WSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCG 2815
+ SG +P ++ P + D+ ++ + L+
Sbjct: 401 NDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFE 460
Query: 2816 LDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLR-----GS 2870
D + L H + T+ DP + PG + FSC G+ L +
Sbjct: 461 EDRCFAPFLAHGNVTTT----DP-----------EYRPGALATFSCLPGYALEPPGPPNA 505
Query: 2871 SERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATG-- 2928
E W+ ++P C + G P A VV S S S +C G +
Sbjct: 506 IECVDPTEPHWNDTEPACKAMCGGELSEP--AGVVLSPDWPQSYSPGQDCVWGVHVQEEK 563
Query: 2929 --------LLSRHCSVNGTWTGSDPECLVI-NCGDPGIPANGLRLGNDFRYNKTVTYQCV 2979
L R + + G P V+ P L G D T+ +Q
Sbjct: 564 RILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDL----TLQFQAP 619
Query: 2980 PGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSSVTYACL 3039
PG + K+ N T P PPP D + G+ +TY C
Sbjct: 620 PGPPNPGLGQGFVLHFKEVPRNDTCPEL------PPPEWGWRTASHGDLIRGTVLTYQCE 673
Query: 3040 EGYQLSLPAVFTCEGNGSWTGELPQCFPVF-CGDPGVPSRGRR--EDRGFSYRSSVSFSC 3096
GY+L + TC+ + SW+ P C + C DPG + G R D GF S V + C
Sbjct: 674 PGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRC 733
Query: 3097 HPPLVLVGSPRRFCQSDGT----WSGTQPSCIDPTLTTCADPGVPQFGIQN-NSQGYQVG 3151
P L G+ C S T WS P C C +PGVP+ G Q YQ G
Sbjct: 734 LPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCA-LKYEPCLNPGVPENGYQTLYKHHYQAG 792
Query: 3152 STVLFRCQKGYLLQGSTTRTCLPN--LTWSGTPPDCVPHHCRQPETPTHAN--------- 3200
++ F C +G+ L G T TC+P W+ PP C P
Sbjct: 793 ESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVTQTTDPSRQLEGGNLALAILLP 852
Query: 3201 VGALDLPSMGYTLIYSCQEGFSLKGGS 3227
+G + + G + Y+ +G SL G S
Sbjct: 853 LGLVIVLGSGVYIYYTKLQGKSLFGFS 879
Score = 102 bits (253), Expect = 9e-21
Identities = 139/573 (24%), Positives = 200/573 (34%), Gaps = 129/573 (22%)
Query: 2771 LVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMC--GLDGHWTGSLPHCS 2828
L+SCG P P H +S G + C L G T +C G W G P C
Sbjct: 287 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 346
Query: 2829 GTSVGVCGDPGIPAHGIRLGD--SFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQP 2886
+ G H LG S +PG + + V+ + R +
Sbjct: 347 ASCGGTI-------HNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDE 399
Query: 2887 ECGVISCGNPGTPSNARVVFSD-------GLVFSSSIVYECREGYYATGLLSRHCSVNGT 2939
+ + + G+P + + SD GL+ + +Y LLS
Sbjct: 400 DNDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLY--------VELLSE------- 444
Query: 2940 WTGSDPECLVIN--------CGDPGIP-ANGLRLGNDFRYNKTVTYQCVPGYMMESHRV- 2989
T ++P L + C P + N ++R T+ C+PGY +E
Sbjct: 445 -TPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPP 503
Query: 2990 SVLSCTK--DRTWNGTKPVCKAL----MCKPPPLI-----PNGKVVGSDFMWGSSVTYA- 3037
+ + C + WN T+P CKA+ + +P ++ P G D +WG V
Sbjct: 504 NAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEK 563
Query: 3038 ----------CLEGYQLSLPAVFTCEGNGSWTGEL----------------PQCFPVFCG 3071
EG L+L +G+G L P F
Sbjct: 564 RILLQVEILNVREGDMLTL-----FDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQA 618
Query: 3072 DPGVPSRG----------------------------RREDRGFSYRSSV-SFSCHPPLVL 3102
PG P+ G R G R +V ++ C P L
Sbjct: 619 PPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYEL 678
Query: 3103 VGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQ-GYQVGSTVLFRCQKG 3161
+GS CQ D +WS P+C + TCADPG G + S G+ VGS V +RC G
Sbjct: 679 LGSDILTCQWDLSWSAAPPAC--QKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPG 736
Query: 3162 YLLQGSTTRTCLPNLT----WSGTPPDCVPHH--CRQPETPTHANVGALDLP-SMGYTLI 3214
Y L+G+ TC T WS P C + C P P + G +L
Sbjct: 737 YSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLR 796
Query: 3215 YSCQEGFSLKGGSEHRTCKAD--GSWTGKPPIC 3245
+ C EGF L G TC WT +PP+C
Sbjct: 797 FFCYEGFELIG-EVTITCVPGHPSQWTSQPPLC 828
Score = 99.0 bits (245), Expect = 7e-20
Identities = 100/396 (25%), Positives = 156/396 (39%), Gaps = 17/396 (4%)
Query: 2180 VPCGGNITSSNGTVYSPGFPSPYSSSQ---DCVWLITVPIGHGVRLNLSLLQTEPSGDFI 2236
V C NI+ G V SP SP S + DC + I V G+G+ + + L + +
Sbjct: 171 VLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELL 230
Query: 2237 TI-WDGPQQTAPRLGVFTRSMAK-KTVQSSSNQVLLKFHRD-AATGGIFAIAFSAYPLTK 2293
+ G APRL + + + + ++S +N++LL F GG F I + AY L+
Sbjct: 231 VLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLSC 290
Query: 2294 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEV 2353
PP VT + + G + C G+ L G E L C GT + G P C
Sbjct: 291 GFPPRPAHGDVSVT---DLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMA 347
Query: 2354 HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEI 2413
C + + G I+S G+ TC W++ + L E ++ D +
Sbjct: 348 SC-GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMV 406
Query: 2414 FDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA---PYCSL 2470
G S SP++ + + S + S+Y+ S+ N +R+ A C
Sbjct: 407 RSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFA 466
Query: 2471 PRAPLHGFILGQTSTQPGGSIHFGCNAGYRL--VGHSMAICTRHPQGYHLWSEAIPLCQA 2528
P +PG F C GY L G AI P H W++ P C+A
Sbjct: 467 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPH-WNDTEPACKA 525
Query: 2529 LSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQ 2564
+ CG + G+V ++ C G H+Q
Sbjct: 526 M-CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQ 560
Score = 60.8 bits (146), Expect = 2e-08
Identities = 57/215 (26%), Positives = 89/215 (41%), Gaps = 20/215 (9%)
Query: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG 85
C +L P G V SP +P Y +C W + +E+ RI L + + E D+L++FDG
Sbjct: 527 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDG 585
Query: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVS----AQGFHATYEVLP-SHTCG 140
+ +L G Q ++S+ L+L+ + QGF ++ +P + TC
Sbjct: 586 DGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTC- 644
Query: 141 NPGRLPNGIQQGSTFNLGDKVR-----YSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
LP T + GD +R Y C G+ L G +LTC + +W P+
Sbjct: 645 --PELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPA 698
Query: 196 CRADDACG--GTLRGQSGIISSPHFPSEYHNNADC 228
C+ C G + S FP H C
Sbjct: 699 CQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRC 733
Score = 47.4 bits (111), Expect = 3e-04
Identities = 49/159 (30%), Positives = 63/159 (39%), Gaps = 19/159 (11%)
Query: 2750 GMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGN 2809
G + I Q + S + VL G PG P + G V+R S + L
Sbjct: 211 GYGIEIQVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLR-SPTNRLLLHFQ 269
Query: 2810 STRMC---GLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHV 2866
S R+ G H+ L C G P PAHG PG F C++G+
Sbjct: 270 SPRVPRGGGFRIHYQAYLLSC--------GFPPRPAHGDVSVTDLHPGGTATFHCDSGYQ 321
Query: 2867 LRGSSERTCQANG---SWSGSQPECGVISCGNPGTPSNA 2902
L+G C NG SW+G P C + SCG GT NA
Sbjct: 322 LQGEETLIC-LNGTRPSWNGETPSC-MASCG--GTIHNA 356
Score = 38.5 bits (88), Expect = 0.12
Identities = 18/64 (28%), Positives = 28/64 (43%)
Query: 2946 ECLVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKP 3005
+ +++CG P PA+G D T T+ C GY ++ + +WNG P
Sbjct: 284 QAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETP 343
Query: 3006 VCKA 3009
C A
Sbjct: 344 SCMA 347
>gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [Homo
sapiens]
Length = 853
Score = 232 bits (591), Expect = 6e-60
Identities = 158/518 (30%), Positives = 253/518 (48%), Gaps = 21/518 (4%)
Query: 1098 CGNSVTGTQGTLLSPNF--PVNYNNNH-ECIYSIQTQPGKGIQLKARAFELSEGDVLKVY 1154
C N+++ +G + SP+ PV+ +C YSI PG GI+++ + LS+ + L V
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1155 DGNNNSARLLGVFSHSEMMGV--TLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCE 1212
G + + ++S M+G L S ++ L L F + GF +H+ ++ L+ C
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAY-LLSCG 221
Query: 1213 DPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECG 1272
P P G + H G + +F CD GY L+G E L+CL+G R +W+ P+C+A CG
Sbjct: 222 FPPRPAHGDVSVTDLH-PGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 280
Query: 1273 GTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGP 1332
GT+ G+++SP NL C W IEA G + LHF +E +D L + G
Sbjct: 281 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 340
Query: 1333 VESGVLLKELSGPALP-KDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIP 1391
++ + +P + L S S+ ++ ++ + +++F C P +
Sbjct: 341 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 400
Query: 1392 Q-NGSRSGDSWEAGDSTVFQCDPGYALQGSA---EISCVKIENRFFWQPSPPTCIAPCGG 1447
N + + + G F C PGYAL+ I CV W + P C A CGG
Sbjct: 401 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVD-PTEPHWNDTEPACKAMCGG 459
Query: 1448 DLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDS 1507
+L+ P+GV+LSP++P+ Y PG++C W V V + I L I N+ G D L ++DG
Sbjct: 460 ELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGP 518
Query: 1508 LSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSN----AGFVIDYTENPR-ESCFDPG 1562
+ ++ G Q R+ SS L L F++ N GFV+ + E PR ++C +
Sbjct: 519 SARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELP 578
Query: 1563 SIKNGTRVGS--DLKLGSSVTYYCHGGYEVEGTSTLSC 1598
+ G R S DL G+ +TY C GYE+ G+ L+C
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC 616
Score = 201 bits (510), Expect = 1e-50
Identities = 189/747 (25%), Positives = 301/747 (40%), Gaps = 79/747 (10%)
Query: 1278 EVSGQVLSPGYPAPYEHNL---NCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDG--P 1332
E G V SP +P L +C ++I G I + + + ++L + G P
Sbjct: 109 EGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSP 168
Query: 1333 VESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQ 1392
+ LL S + L S N ++L F + GF I + + SC P P
Sbjct: 169 GLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQ-AYLLSCGFPPRPA 227
Query: 1393 NGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGP 1452
+G S G + F CD GY LQG + C+ R W P+C+A CGG +
Sbjct: 228 HGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN-GTRPSWNGETPSCMASCGGTIHNA 286
Query: 1453 S-GVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPL 1511
+ G I+SP P C W + + + L F +L+ D L + G LSP+
Sbjct: 287 TLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPV 346
Query: 1512 IGSFYGSQLPGR-IESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSIK-NGTR 1569
I +P R + S + SL++ S+ + + + + CF P N T
Sbjct: 347 IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTT 406
Query: 1570 VGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDG-KPVWNNPRPVCTAPCGGQYVGSDG 1628
+ + G+ T+ C GY +E + I D +P WN+ P C A CGG+ G
Sbjct: 407 TDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAG 466
Query: 1629 VVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSL 1688
VVLSP++PQ+Y+ GQ C++ V V ++ + Q + D++ + DG +R+L+ L
Sbjct: 467 VVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSARVLAQL 526
Query: 1689 SGSHTGESLPLATSNQVLIKFSAKGLAP----ARGFHFVYQAVPRTSATQCSSVPEPRYG 1744
G L L++ + ++F A P +GF ++ VPR C +P P +G
Sbjct: 527 RGPQPRRRL-LSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT--CPELPPPEWG 583
Query: 1745 KRLGS--DFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC--VVPCG--G 1798
R S D G ++ ++C GY L GS + C W+ + P C ++ C G
Sbjct: 584 WRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPACQKIMTCADPG 639
Query: 1799 NLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADN 1858
+ T GF P G+ +Q + + + +GA
Sbjct: 640 EIANGHRTASDAGF----------------PVGSHVQYRCLPGYS---------LEGA-- 672
Query: 1859 TVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNG 1918
A+L S +SD A L+Y+ C P VP NG
Sbjct: 673 --------------AMLTCYSRDTGTPKWSDRVPKCA---LKYE-----PCLNPGVPENG 710
Query: 1919 VKT--GERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEME 1976
+T Y + + F C G+ L G I+C+PG +W PPLC ++ +
Sbjct: 711 YQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVAYEELLDNRK 770
Query: 1977 GVILSPGFPGNYPSNMDCSWKIALPVG 2003
+ P + + I LP+G
Sbjct: 771 LEVTQTTDPSRQLEGGNLALAILLPLG 797
Score = 199 bits (506), Expect = 4e-50
Identities = 190/743 (25%), Positives = 304/743 (40%), Gaps = 81/743 (10%)
Query: 722 LGTQGSE--TITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSP--GWP-GFYKDAL 776
LG +G E T T ++ +V + + C +++ G + SP G P L
Sbjct: 74 LGPEGGEEETTTTIITTTTV---TTTVTSPVLCNNNISEGEGYVESPDLGSPVSRTLGLL 130
Query: 777 SCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYS-AP-LIGVYHGTQVPQFLIST 834
C + I PGY I+I + L + G + AP L+ Q L S
Sbjct: 131 DCTYSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSP 190
Query: 835 SNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCD 894
+N L L F + + GF++ Y+ L C P P +G D + G TF CD
Sbjct: 191 TNRLLLHFQSPRVPRGGGFRIHYQAYLLS---CGFPPRPAHGDVSVTDLHPGGTATFHCD 247
Query: 895 SGYTLSDGEPLECEPNFQ--WSRALPSCEALCGGFIQGSS-GTILSPGFPDFYPNNLNCT 951
SGY L E L C + W+ PSC A CGG I ++ G I+SP NL C
Sbjct: 248 SGYQLQGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCR 307
Query: 952 WIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFT 1011
W+IE + G+ + F L+ +D L++ GS P+ + S + GL +
Sbjct: 308 WVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPV--IYDSDMDDVPERGLISDAQ 365
Query: 1012 A-QVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRK-GLQFGVGDTLTFSCFPGY 1069
+ V +S+ + ++ F ++ + C P + ++ ++ G TFSC PGY
Sbjct: 366 SLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGY 425
Query: 1070 RLEGTA---RITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIY 1126
LE I C+ W+ P C A CG ++ G +LSP++P +Y+ +C++
Sbjct: 426 ALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVW 485
Query: 1127 SIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWL 1186
+ Q K I L+ + EGD+L ++DG+ SAR+L + L S+ L L
Sbjct: 486 GVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRR-RLLSSGPDLTL 544
Query: 1187 DFITDA----ENTSKGFELHFSSF-ELIKCEDPGTPKFGYKVHDEGH-FAGSSVSFSCDP 1240
F +GF LHF C + P++G++ G G+ +++ C+P
Sbjct: 545 QFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEP 604
Query: 1241 GYSLRGSEELLCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIW 1300
GY L GS+ L C WD C + G++ + A
Sbjct: 605 GYELLGSDILTC------QWDLSWSAAPPACQKIMTCADPGEIANGHRTA---------- 648
Query: 1301 TIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVL 1360
++AG +G H V + L G +L +++
Sbjct: 649 ---SDAGFPVGSH-----------------------VQYRCLPGYSLEG------AAMLT 676
Query: 1361 QFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQNGSRS--GDSWEAGDSTVFQCDPGYALQ 1418
+S D T K + C +PG+P+NG ++ ++AG+S F C G+ L
Sbjct: 677 CYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELI 736
Query: 1419 GSAEISCVKIENRFFWQPSPPTC 1441
G I+CV + W PP C
Sbjct: 737 GEVTITCVP-GHPSQWTSQPPLC 758
Score = 176 bits (447), Expect = 3e-43
Identities = 170/633 (26%), Positives = 253/633 (39%), Gaps = 85/633 (13%)
Query: 1619 CGGQYVGSDGVVLSPNY--PQNYTSGQI-CLYFVTVPKDYVVFGQFAFFHTALNDVVEVH 1675
C +G V SP+ P + T G + C Y + V Y + Q + + + + V
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1676 DGHSQHS---RLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSA 1732
G RLL++ S G+ L T N++L+ F + + GF YQA
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPT-NRLLLHFQSPRVPRGGGFRIHYQAY----L 217
Query: 1733 TQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC 1792
C P P +G +D G F C+SGY LQG + CL G WN P+C
Sbjct: 218 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN--GTRPSWNGETPSC 275
Query: 1793 VVPCGGNLTERR-GTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLE 1851
+ CGG + G I+SP +L C W I EG + + +++ D L
Sbjct: 276 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 335
Query: 1852 VFDGADNTVTMLGSFSGTTVPAL-LNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCP 1910
V G ++ VP L S + LY+ S+ + L ++ C
Sbjct: 336 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 395
Query: 1911 EPAVPSNGVKTGE-RYLVNDVVSFQCEPGYALQGHAH---ISCMPGTVRRWNYPPPLCIA 1966
P + V T + Y + +F C PGYAL+ I C+ T WN P C A
Sbjct: 396 APFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKA 455
Query: 1967 QCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQ-------FLNFSTEPNH 2019
CGG + E GV+LSP +P +Y DC W G H+Q +
Sbjct: 456 MCGGELSEPAGVVLSPDWPQSYSPGQDCVW--------GVHVQEEKRILLQVEILNVREG 507
Query: 2020 DYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRP----GFKLEYQD 2075
D + + +G ++R++ + G + LLS+ + T+ F + P GF L +++
Sbjct: 508 DMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKE 567
Query: 2076 L-----------------TYSHQISSFLRGFDLS-------ELERTNSTPPVAASYVWDL 2111
+ T SH +RG L+ EL ++ + WDL
Sbjct: 568 VPRNDTCPELPPPEWGWRTASH--GDLIRGTVLTYQCEPGYELLGSD-----ILTCQWDL 620
Query: 2112 D-----PGCEAYELQECPDPEPFANG--IVRGAGYNVGQSVTFECLPGYQLTGHPVLTC- 2163
P C+ ++ C DP ANG AG+ VG V + CLPGY L G +LTC
Sbjct: 621 SWSAAPPACQ--KIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCY 678
Query: 2164 --QHGTNRNWDHPLPKCEV---PCGGNITSSNG 2191
GT + W +PKC + PC NG
Sbjct: 679 SRDTGTPK-WSDRVPKCALKYEPCLNPGVPENG 710
Score = 176 bits (446), Expect = 4e-43
Identities = 169/712 (23%), Positives = 281/712 (39%), Gaps = 76/712 (10%)
Query: 404 MCDAHLRGPSGIITSPNFPIQYDNNA---HCVWIITALNPSKVIKLAFEEFDLERGYDTL 460
+C+ ++ G + SP+ C + I P I++ + +L + + L
Sbjct: 102 LCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVY-PGYGIEIQVQTLNLSQEEELL 160
Query: 461 TVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGS 520
+ GG G +L + ++ S +++ L FQ+ GF+ Y+ S
Sbjct: 161 VLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-S 219
Query: 521 CGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQ--WSAKKPGCVFSC 578
CG P PA+G + H G T F C ++L G++ + C + W+ + P C+ SC
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASC 279
Query: 579 FFNFTSPS-GVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDG 637
+ + G ++SP G +L C W+I A R+HL F + ++ D L+++ G
Sbjct: 280 GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSG 339
Query: 638 ATAEAPVLGTFSGNQLPS-SITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGV 696
+ +PV+ + +P + S +E ++ ++ F F + C P +
Sbjct: 340 GSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFL 399
Query: 697 PVNGKRFGD-SLQLGSSISFLCDEGF-LGTQGSETITCVLKEGSVVWNSAVLRCEAPCGG 754
D + G+ +F C G+ L G + WN C+A CGG
Sbjct: 400 AHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGG 459
Query: 755 HLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTY 814
L+ P+G +LSP WP Y C W + Q I + + D L + DG
Sbjct: 460 ELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGP 518
Query: 815 SAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIG----FQLRYETITLQSDHCLDP 870
SA ++ G Q + L+S+ L L F + G F L ++ + ++D C +
Sbjct: 519 SARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVP-RNDTCPEL 577
Query: 871 GIPVNGQR---HGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGGF 927
P G R HG D G ++T+ C+ GY L + L C+ + WS A P+C+ +
Sbjct: 578 PPPEWGWRTASHG-DLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIM--- 633
Query: 928 IQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFT 987
T PG E ++G H ++G GS
Sbjct: 634 ------TCADPG---------------EIANG-------HRTASDAGFPV------GSHV 659
Query: 988 QPLRQLTGSRLPAPISAGLYGNFTAQVRF---ISDFSMSYEGFNITFSEYDLEPCEEPEV 1044
Q R L G L Y T ++ + ++ YE PC P V
Sbjct: 660 Q-YRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYE------------PCLNPGV 706
Query: 1045 P--AYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRC 1094
P Y + G++L F C+ G+ L G ITC+ G W+S P C
Sbjct: 707 PENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 758
Score = 168 bits (425), Expect = 1e-40
Identities = 168/715 (23%), Positives = 274/715 (38%), Gaps = 84/715 (11%)
Query: 1968 CGGTVEEMEGVILSP--GFPGNYPSNM-DCSWKIALPVGFGAHIQFLNFSTEPNHDYIEI 2024
C + E EG + SP G P + + DC++ I + G+G IQ + + + +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 2025 RNG--PYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQI 2082
G P R++ S L S ++ ++F S GF++ YQ
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQ-------- 214
Query: 2083 SSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVG 2142
AY L C P A+G V + G
Sbjct: 215 ----------------------------------AY-LLSCGFPPRPAHGDVSVTDLHPG 239
Query: 2143 QSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSSN-GTVYSPGFPSP 2201
+ TF C GYQL G L C +GT +W+ P C CGG I ++ G + SP
Sbjct: 240 GTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGA 299
Query: 2202 YSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSM----A 2257
+ C W+I G + L+ + + D + + G +P ++ M
Sbjct: 300 VGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSP--VIYDSDMDDVPE 357
Query: 2258 KKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDI 2317
+ + + + + A + ++ F A+ +C P L + V T + E+ G +
Sbjct: 358 RGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP-FLAHGNVTTTDPEYRPGAL 416
Query: 2318 VRYRCLPGFTLV---GNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYP 2374
+ CLPG+ L + C T + P C+ C L++ GV+LS +P
Sbjct: 417 ATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGE--LSEPAGVVLSPDWP 474
Query: 2375 GSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAP 2434
SY Q C W V V+ + I L VE L+ ++ D +FDG + +L L G
Sbjct: 475 QSYSPGQDCVWGVHVQEEKRILLQVE-ILNVREGDMLTLFDGDGPSARVLAQLRGPQPRR 533
Query: 2435 LIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPR--------APLHGFILGQTSTQ 2486
++ SS + L++ + G + + +PR P G+
Sbjct: 534 RLL-SSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDL 592
Query: 2487 PGGSI-HFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQ-ALSCGLPEAPKNGMVFG 2544
G++ + C GY L+G + C Q WS A P CQ ++C P NG
Sbjct: 593 IRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPACQKIMTCADPGEIANGHRTA 648
Query: 2545 KE--YTVGTKAMYSCSEGYHLQAGAEATAECLDTGL--WSNRNVPPQCVPVTCPDVSSIS 2600
+ + VG+ Y C GY L+ A T DTG WS+R P+C P ++
Sbjct: 649 SDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDR--VPKCALKYEPCLNPGV 706
Query: 2601 VEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRI 2655
E+G ++ +++ YQ L C G+ G+ I C P C++
Sbjct: 707 PENG-YQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKV 760
Score = 140 bits (354), Expect = 2e-32
Identities = 153/572 (26%), Positives = 237/572 (41%), Gaps = 68/572 (11%)
Query: 26 CTFQLHGPNGTVESP--GFPYGYP-NYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSV 82
C + G VESP G P +CT++I + I++ Q+ L ++ ++L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 83 FDG--PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCG 140
G P L + + S L L S GF Y+ +CG
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-SCG 221
Query: 141 NPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADD 200
P R +G + + G + C+ G+ L+G L C G+ S W+ PSC A
Sbjct: 222 FPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPS--WNGETPSCMA-- 277
Query: 201 ACGGTLRGQS-GIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVT 259
+CGGT+ + G I SP N C W I A G + L F L++ D L V
Sbjct: 278 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 337
Query: 260 GTEGSSLWFTGASLPAPVISSKNWLRLHFTSD-GNHRQRGFSAQYQVKKQIELKSR---G 315
+G S +PVI + SD + +RG + Q +EL S
Sbjct: 338 ---------SGGSPLSPVI---------YDSDMDDVPERGLISDAQ-SLYVELLSETPAN 378
Query: 316 VKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDL 375
L+ + + + ++ G+ DP ++R G+ F+C GY L
Sbjct: 379 PLLLSLRFEAFEEDRCFAPFLAHGNVTTTDP-----------EYRPGALATFSCLPGYAL 427
Query: 376 Q---GSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCV 432
+ I C+ ++ W+D P C+A MC L P+G++ SP++P Y CV
Sbjct: 428 EPPGPPNAIECVDPTE--PHWNDTEPACKA-MCGGELSEPAGVVLSPDWPQSYSPGQDCV 484
Query: 433 WIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNH 492
W + + K I L E ++ G D LT+ DG DG VL L G ++S+
Sbjct: 485 WGV-HVQEEKRILLQVEILNVREG-DMLTLFDG--DGPSARVLAQLRGPQPRRRLLSSGP 540
Query: 493 QMWLLFQT----DGSGSSLGFKASYEEIEQG-SCGDPGIPAYGRREGSRFHHGD-----T 542
+ L FQ G GF ++E+ + +C + P +G R S HGD
Sbjct: 541 DLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTAS---HGDLIRGTV 597
Query: 543 LKFECQPAFELVGQKAITCQKNNQWSAKKPGC 574
L ++C+P +EL+G +TCQ + WSA P C
Sbjct: 598 LTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 629
Score = 139 bits (351), Expect = 4e-32
Identities = 192/848 (22%), Positives = 296/848 (34%), Gaps = 155/848 (18%)
Query: 202 CGGTLRGQSGIISSPHFPSEYHNNA---DCTWTILAELGDTIALVFIDFQLEDGYDFLEV 258
C + G + SP S DCT++I G I + L + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 259 TG----------TEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQ 308
G SS+ G L +P N L LHF S R GF YQ
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPT----NRLLLHFQSPRVPRGGGFRIHYQAYLL 218
Query: 309 IELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFT 368
C P P G +D G + F
Sbjct: 219 ---------------------------------SCGFPPRPAHGDVSVTDLHPGGTATFH 245
Query: 369 CNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNN 428
C+ GY LQG + + C+ + +W+ P C A G I SP N
Sbjct: 246 CDSGYQLQGEETLICLNGTR--PSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPN 303
Query: 429 AHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDL-I 487
C W+I A + + L FE L+ D L V GG V+Y VP+ +
Sbjct: 304 LTCRWVIEAAEGRR-LHLHFERVSLDEDNDRLMVRSGGSP--LSPVIYDSDMDDVPERGL 360
Query: 488 VSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGR--REGSRFHHGDTLKF 545
+S +++ ++ + L +E E+ C P + A+G + G F
Sbjct: 361 ISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFL-AHGNVTTTDPEYRPGALATF 419
Query: 546 ECQPAFELVGQ---KAITCQKNNQ--WSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGN 600
C P + L AI C + W+ +P C C + P+GVVLSP++P+ Y
Sbjct: 420 SCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSP 479
Query: 601 HLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSS 660
CVW + + E RI L ++V + D L + DG A VL G Q + SS
Sbjct: 480 GQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSS 538
Query: 661 GHVARLEFQTDHSTGKRGFNITFTTF-----RHNECPDPGVPVNGKR---FGDSLQLGSS 712
G L+FQ G F R++ CP+ P G R GD ++ G+
Sbjct: 539 GPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIR-GTV 597
Query: 713 ISFLCDEGFLGTQGSETITCVLKEGSVVWNSA------VLRCEAPCGGHLTSPSGTILSP 766
+++ C+ G+ GS+ +TC + + W++A ++ C P G + + T
Sbjct: 598 LTYQCEPGY-ELLGSDILTC---QWDLSWSAAPPACQKIMTCADP--GEIANGHRTASDA 651
Query: 767 GWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVY-HGT 825
G+P C PGY ++ A ++ Y T
Sbjct: 652 GFPVGSHVQYRCL------PGYSLE-----------------------GAAMLTCYSRDT 682
Query: 826 QVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQR--HGNDF 883
P++ SD R L+ + CL+PG+P NG + + + +
Sbjct: 683 GTPKW------------------SD-----RVPKCALKYEPCLNPGVPENGYQTLYKHHY 719
Query: 884 YVGALVTFSCDSGYTLSDGEPLECEPNF--QWSRALPSCEALCGGFIQGSSGTILSPGFP 941
G + F C G+ L + C P QW+ P C+ + + P
Sbjct: 720 QAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVAYEELLDNRKLEVTQTTDP 779
Query: 942 --DFYPNNLNCTWIIETS----HGKGVFFTF------HTFHLESGHDYLLITENGSFTQP 989
NL ++ G GV+ + F H Y IT F+ P
Sbjct: 780 SRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGSHSYSPITVESDFSNP 839
Query: 990 LRQLTGSR 997
L + +R
Sbjct: 840 LYEAGDTR 847
Score = 117 bits (294), Expect = 2e-25
Identities = 150/576 (26%), Positives = 211/576 (36%), Gaps = 79/576 (13%)
Query: 2655 IISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGL---WSGSEVRC 2711
++SCG P P +G T G TA F C+SGY L G C+ NG W+G C
Sbjct: 217 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSC 275
Query: 2712 LAGHCGT-----------PEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDH 2760
+A GT PEP G G N + R V + G RL R+ +
Sbjct: 276 MASCGGTIHNATLGRIVSPEP---GGAVGPNLTCRW--VIEAAEGRRLHLHFERVSLDED 330
Query: 2761 H-----WSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCG 2815
+ SG +P ++ P + D+ ++ + L+
Sbjct: 331 NDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFE 390
Query: 2816 LDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLR-----GS 2870
D + L H + T+ DP + PG + FSC G+ L +
Sbjct: 391 EDRCFAPFLAHGNVTTT----DP-----------EYRPGALATFSCLPGYALEPPGPPNA 435
Query: 2871 SERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATG-- 2928
E W+ ++P C + G P A VV S S S +C G +
Sbjct: 436 IECVDPTEPHWNDTEPACKAMCGGELSEP--AGVVLSPDWPQSYSPGQDCVWGVHVQEEK 493
Query: 2929 --------LLSRHCSVNGTWTGSDPECLVI-NCGDPGIPANGLRLGNDFRYNKTVTYQCV 2979
L R + + G P V+ P L G D T+ +Q
Sbjct: 494 RILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDL----TLQFQAP 549
Query: 2980 PGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSSVTYACL 3039
PG + K+ N T P PPP D + G+ +TY C
Sbjct: 550 PGPPNPGLGQGFVLHFKEVPRNDTCPEL------PPPEWGWRTASHGDLIRGTVLTYQCE 603
Query: 3040 EGYQLSLPAVFTCEGNGSWTGELPQCFPVF-CGDPGVPSRGRR--EDRGFSYRSSVSFSC 3096
GY+L + TC+ + SW+ P C + C DPG + G R D GF S V + C
Sbjct: 604 PGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRC 663
Query: 3097 HPPLVLVGSPRRFCQSDGT----WSGTQPSCIDPTLTTCADPGVPQFGIQN-NSQGYQVG 3151
P L G+ C S T WS P C C +PGVP+ G Q YQ G
Sbjct: 664 LPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCA-LKYEPCLNPGVPENGYQTLYKHHYQAG 722
Query: 3152 STVLFRCQKGYLLQGSTTRTCLPN--LTWSGTPPDC 3185
++ F C +G+ L G T TC+P W+ PP C
Sbjct: 723 ESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 758
Score = 102 bits (253), Expect = 9e-21
Identities = 139/573 (24%), Positives = 200/573 (34%), Gaps = 129/573 (22%)
Query: 2771 LVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMC--GLDGHWTGSLPHCS 2828
L+SCG P P H +S G + C L G T +C G W G P C
Sbjct: 217 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Query: 2829 GTSVGVCGDPGIPAHGIRLGD--SFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQP 2886
+ G H LG S +PG + + V+ + R +
Sbjct: 277 ASCGGTI-------HNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDE 329
Query: 2887 ECGVISCGNPGTPSNARVVFSD-------GLVFSSSIVYECREGYYATGLLSRHCSVNGT 2939
+ + + G+P + + SD GL+ + +Y LLS
Sbjct: 330 DNDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLY--------VELLSE------- 374
Query: 2940 WTGSDPECLVIN--------CGDPGIP-ANGLRLGNDFRYNKTVTYQCVPGYMMESHRV- 2989
T ++P L + C P + N ++R T+ C+PGY +E
Sbjct: 375 -TPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPP 433
Query: 2990 SVLSCTK--DRTWNGTKPVCKAL----MCKPPPLI-----PNGKVVGSDFMWGSSVTYA- 3037
+ + C + WN T+P CKA+ + +P ++ P G D +WG V
Sbjct: 434 NAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEK 493
Query: 3038 ----------CLEGYQLSLPAVFTCEGNGSWTGEL----------------PQCFPVFCG 3071
EG L+L +G+G L P F
Sbjct: 494 RILLQVEILNVREGDMLTL-----FDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQA 548
Query: 3072 DPGVPSRG----------------------------RREDRGFSYRSSV-SFSCHPPLVL 3102
PG P+ G R G R +V ++ C P L
Sbjct: 549 PPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYEL 608
Query: 3103 VGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQ-GYQVGSTVLFRCQKG 3161
+GS CQ D +WS P+C + TCADPG G + S G+ VGS V +RC G
Sbjct: 609 LGSDILTCQWDLSWSAAPPAC--QKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPG 666
Query: 3162 YLLQGSTTRTCLPNLT----WSGTPPDCVPHH--CRQPETPTHANVGALDLP-SMGYTLI 3214
Y L+G+ TC T WS P C + C P P + G +L
Sbjct: 667 YSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLR 726
Query: 3215 YSCQEGFSLKGGSEHRTCKAD--GSWTGKPPIC 3245
+ C EGF L G TC WT +PP+C
Sbjct: 727 FFCYEGFELIG-EVTITCVPGHPSQWTSQPPLC 758
Score = 99.0 bits (245), Expect = 7e-20
Identities = 100/396 (25%), Positives = 156/396 (39%), Gaps = 17/396 (4%)
Query: 2180 VPCGGNITSSNGTVYSPGFPSPYSSSQ---DCVWLITVPIGHGVRLNLSLLQTEPSGDFI 2236
V C NI+ G V SP SP S + DC + I V G+G+ + + L + +
Sbjct: 101 VLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELL 160
Query: 2237 TI-WDGPQQTAPRLGVFTRSMAK-KTVQSSSNQVLLKFHRD-AATGGIFAIAFSAYPLTK 2293
+ G APRL + + + + ++S +N++LL F GG F I + AY L+
Sbjct: 161 VLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLSC 220
Query: 2294 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEV 2353
PP VT + + G + C G+ L G E L C GT + G P C
Sbjct: 221 GFPPRPAHGDVSVT---DLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMA 277
Query: 2354 HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEI 2413
C + + G I+S G+ TC W++ + L E ++ D +
Sbjct: 278 SC-GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMV 336
Query: 2414 FDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA---PYCSL 2470
G S SP++ + + S + S+Y+ S+ N +R+ A C
Sbjct: 337 RSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFA 396
Query: 2471 PRAPLHGFILGQTSTQPGGSIHFGCNAGYRL--VGHSMAICTRHPQGYHLWSEAIPLCQA 2528
P +PG F C GY L G AI P H W++ P C+A
Sbjct: 397 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPH-WNDTEPACKA 455
Query: 2529 LSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQ 2564
+ CG + G+V ++ C G H+Q
Sbjct: 456 M-CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQ 490
Score = 75.9 bits (185), Expect = 7e-13
Identities = 47/165 (28%), Positives = 74/165 (44%), Gaps = 10/165 (6%)
Query: 2854 GTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPEC-GVISCGNPGTPSNARVVFSD-GLV 2911
GTV+ + CE G+ L GS TCQ + SWS + P C +++C +PG +N SD G
Sbjct: 595 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFP 654
Query: 2912 FSSSIVYECREGYYATGLLSRHCSVNGT----WTGSDPECLV--INCGDPGIPANGLR-- 2963
S + Y C GY G C T W+ P+C + C +PG+P NG +
Sbjct: 655 VGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTL 714
Query: 2964 LGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCK 3008
+ ++ +++ + C G+ + W P+CK
Sbjct: 715 YKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCK 759
Score = 73.2 bits (178), Expect = 4e-12
Identities = 50/168 (29%), Positives = 75/168 (44%), Gaps = 13/168 (7%)
Query: 2735 RGSVV-YQCNAGFRLIGMSVRICQQDHHWSGKTPFC-VLVSCGHPG--SPPHSQMSGDSY 2790
RG+V+ YQC G+ L+G + CQ D WS P C +++C PG + H S +
Sbjct: 594 RGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGF 653
Query: 2791 TVGAVVRYSCIGKRTLVGNSTRMCGL----DGHWTGSLPHCSGTSVGVCGDPGIPAHGIR 2846
VG+ V+Y C+ +L G + C W+ +P C+ C +PG+P +G +
Sbjct: 654 PVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCA-LKYEPCLNPGVPENGYQ 712
Query: 2847 --LGDSFDPGTVMRFSCEAGHVLRGSSERTCQAN--GSWSGSQPECGV 2890
+ G +RF C G L G TC W+ P C V
Sbjct: 713 TLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKV 760
Score = 60.8 bits (146), Expect = 2e-08
Identities = 57/215 (26%), Positives = 89/215 (41%), Gaps = 20/215 (9%)
Query: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG 85
C +L P G V SP +P Y +C W + +E+ RI L + + E D+L++FDG
Sbjct: 457 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDG 515
Query: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVS----AQGFHATYEVLP-SHTCG 140
+ +L G Q ++S+ L+L+ + QGF ++ +P + TC
Sbjct: 516 DGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTC- 574
Query: 141 NPGRLPNGIQQGSTFNLGDKVR-----YSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
LP T + GD +R Y C G+ L G +LTC + +W P+
Sbjct: 575 --PELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPA 628
Query: 196 CRADDACG--GTLRGQSGIISSPHFPSEYHNNADC 228
C+ C G + S FP H C
Sbjct: 629 CQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRC 663
Score = 47.4 bits (111), Expect = 3e-04
Identities = 49/159 (30%), Positives = 63/159 (39%), Gaps = 19/159 (11%)
Query: 2750 GMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGN 2809
G + I Q + S + VL G PG P + G V+R S + L
Sbjct: 141 GYGIEIQVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLR-SPTNRLLLHFQ 199
Query: 2810 STRMC---GLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHV 2866
S R+ G H+ L C G P PAHG PG F C++G+
Sbjct: 200 SPRVPRGGGFRIHYQAYLLSC--------GFPPRPAHGDVSVTDLHPGGTATFHCDSGYQ 251
Query: 2867 LRGSSERTCQANG---SWSGSQPECGVISCGNPGTPSNA 2902
L+G C NG SW+G P C + SCG GT NA
Sbjct: 252 LQGEETLIC-LNGTRPSWNGETPSC-MASCG--GTIHNA 286
Score = 44.7 bits (104), Expect = 0.002
Identities = 39/134 (29%), Positives = 54/134 (40%), Gaps = 6/134 (4%)
Query: 1738 VPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCG 1797
VPE Y + G +RF C G+ L G I C VPG +QW P C V
Sbjct: 706 VPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC--VPGHPSQWTSQPPLCKVAYE 763
Query: 1798 GNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQI--QVVSFVTEQNWDSLEVFDG 1855
L R+ + P L N I++P G I + V + T+ SL F G
Sbjct: 764 ELLDNRKLEVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSG 823
Query: 1856 AD--NTVTMLGSFS 1867
+ + +T+ FS
Sbjct: 824 SHSYSPITVESDFS 837
Score = 38.5 bits (88), Expect = 0.12
Identities = 18/64 (28%), Positives = 28/64 (43%)
Query: 2946 ECLVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKP 3005
+ +++CG P PA+G D T T+ C GY ++ + +WNG P
Sbjct: 214 QAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETP 273
Query: 3006 VCKA 3009
C A
Sbjct: 274 SCMA 277
>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
sapiens]
Length = 986
Score = 217 bits (553), Expect = 1e-55
Identities = 184/688 (26%), Positives = 294/688 (42%), Gaps = 165/688 (23%)
Query: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLE 1851
CGG++ + G I SP +P+ Y S C+W+I V EG + + SF E++ +D LE
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 1852 VFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPE 1911
V DG + T++G + G P + STS++L+L F SD S++ AGF + + E
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF----FKEVDE 550
Query: 1912 PAVPSNGVKTGERYLVNDVVSFQC--EPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCG 1969
+ P+ G E+ +N + S++C +PGY L P R C A CG
Sbjct: 551 CSRPNRG--GCEQRCLNTLGSYKCSCDPGYELA--------PDKRR--------CEAACG 592
Query: 1970 GTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIEIR 2025
G + ++ G I SPG+P YP N +C W++ P + +QF F TE N +D++E+R
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2026 NGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSF 2085
+G S++ G+F GSE P + S + V F SD++ ++ GFK +
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS---------- 702
Query: 2086 LRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQSV 2145
D E + N GC+ Q+C N S
Sbjct: 703 ----DKDECSKDNG--------------GCQ----QDC---------------VNTFGSY 725
Query: 2146 TFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSPYSSS 2205
+C G+ L + +H E C +TS++GT+ SP +P Y S
Sbjct: 726 ECQCRSGFVLHDN-----KHDCK----------EAGCDHKVTSTSGTITSPNWPDKYPSK 770
Query: 2206 QDCVWLITVPIGHGVRLNLSLL----QTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTV 2261
++C W I+ GH V+L + Q E + D + ++DG AP LG F S + V
Sbjct: 771 KECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPV 830
Query: 2262 QSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYR 2321
++ +++ L+F+ D + F A T+C G VR
Sbjct: 831 LATGSRMFLRFYSD---NSVQRKGFQASHATEC--------------------GGQVR-- 865
Query: 2322 CLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQ 2381
++ T L ++ QF +YPG
Sbjct: 866 ---------ADVKTKDLYSHAQFG------------------------DNNYPGGV---- 888
Query: 2382 TCSWLVRVEPDYNISLTVEYFLSEKQ----YDEFEIFDGPSGQSPLLKALSGNYSAPLIV 2437
C W++ E Y + L + F E++ YD E+FDG +P L G+ P V
Sbjct: 889 DCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGS-GPPEEV 947
Query: 2438 TSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465
S+ +SV +++ SD +KGF +RY++
Sbjct: 948 YSAGDSVLVKFHSDDTITKKGFHLRYTS 975
Score = 199 bits (506), Expect = 4e-50
Identities = 138/468 (29%), Positives = 223/468 (47%), Gaps = 55/468 (11%)
Query: 404 MCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLER----GYDT 459
+C ++ G I SPN+P Y + C+W I ++ + L F+ F++ER YD
Sbjct: 434 ICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQ-VSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 460 LTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQG 519
L V DG + T++ G PD I ST+ ++WL F +DGS + GF ++ + E
Sbjct: 493 LEVRDG--HSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVD 549
Query: 520 SCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCF 579
C P G E + + K C P +EL K C +C
Sbjct: 550 ECSRPN---RGGCEQRCLNTLGSYKCSCDPGYELAPDKR--------------RCEAACG 592
Query: 580 FNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEP----QFDFLVIK 635
T +G + SP +P++Y + +C+W ++A + RI L F+ + E ++DF+ ++
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 636 DGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPG 695
G TA++ + G F G++ P ITS + R+EF++D++ K+GF F + + D G
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNG 712
Query: 696 VPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGH 755
C + + T GS C + G V+ ++ EA C
Sbjct: 713 G--------------------CQQDCVNTFGSYECQC--RSGFVLHDNKHDCKEAGCDHK 750
Query: 756 LTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRF----KTEVNYDTLEVRDG 811
+TS SGTI SP WP Y C W I + PG+ +K+TF + E YD LEV DG
Sbjct: 751 VTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDG 810
Query: 812 RTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYET 859
R AP++G + G++ P+ +++T + ++L F +D S GFQ + T
Sbjct: 811 RDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT 858
Score = 197 bits (502), Expect = 1e-49
Identities = 140/464 (30%), Positives = 211/464 (45%), Gaps = 57/464 (12%)
Query: 1096 AECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGD-----V 1150
A CG V G + SPN+P +Y + CI+ IQ G + L ++FE+ D
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1151 LKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIK 1210
L+V DG++ S+ L+G + E + STSS LWL F++D GF ++F E+ +
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPD-DIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
Query: 1211 CEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAE 1270
C P + + S SCDPGY L + C A
Sbjct: 551 CSRPNRGGCEQRCLN----TLGSYKCSCDPGYELAPDKR----------------RCEAA 590
Query: 1271 CGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE----VHDVL 1326
CGG + +++G + SPG+P Y N NCIW + A I L F F+TE +D +
Sbjct: 591 CGGFLT-KLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFV 649
Query: 1327 RIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCN 1386
+ G L + G P+ + S +N++ ++F +D SK+GF F S
Sbjct: 650 EVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF-----FSDK 704
Query: 1387 DPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCG 1446
D NG D S QC G+ L + C + A C
Sbjct: 705 DECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKH-DCKE---------------AGCD 748
Query: 1447 GDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP----GYDFLHIY 1502
+T SG I SPN+P+ YP KEC W ++ +P + + L F ++E YD L ++
Sbjct: 749 HKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVF 808
Query: 1503 DGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGF 1546
DGRD+ +P++G F GS+ P + ++ + +FL F SD SV GF
Sbjct: 809 DGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF 852
Score = 190 bits (483), Expect = 2e-47
Identities = 142/479 (29%), Positives = 215/479 (44%), Gaps = 71/479 (14%)
Query: 1443 APCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP----GYDF 1498
A CGGD+ G I SPNYP+ Y P K C W++ VS + + L F F +E YD+
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1499 LHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESC 1558
L + DG S LIG + G + P I+S+S+ L+L F SD S++ AGF +++ + E C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE-C 551
Query: 1559 FDPGSIKNGTRVGSDLKLGSSVTYY---CHGGYEVEGTSTLSCILGPDGKPVWNNPRPVC 1615
P R G + + +++ Y C GYE L PD + C
Sbjct: 552 SRPN------RGGCEQRCLNTLGSYKCSCDPGYE----------LAPDKRR--------C 587
Query: 1616 TAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDV---- 1671
A CGG +G + SP +P+ Y + C++ + P Y + QF FF T NDV
Sbjct: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 1672 -VEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGF--HFVYQAVP 1728
VEV G + S+L GS E + + N + ++F + +GF HF
Sbjct: 648 FVEVRSGLTADSKLHGKFCGSEKPEVIT-SQYNNMRVEFKSDNTVSKKGFKAHFF----- 701
Query: 1729 RTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVS 1788
+ +CS + G + + G+ +C SG+ L + +C
Sbjct: 702 -SDKDECS---KDNGGCQQDCVNTFGSY-ECQCRSGFVLHDNKH-DCKEAG--------- 746
Query: 1789 APTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN-- 1846
C +T GTI SP +P+ Y + C W I G +++ + E
Sbjct: 747 -------CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPE 799
Query: 1847 --WDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 1903
+D LEVFDG D +LG F G+ P + +T ++++L FYSD SV GF + T
Sbjct: 800 CAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT 858
Score = 182 bits (463), Expect = 4e-45
Identities = 143/482 (29%), Positives = 216/482 (44%), Gaps = 62/482 (12%)
Query: 562 QKNNQWSAKKPGCVFS--CFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLA 619
+ ++ W K V+ C + G + SPNYP+DY C+W I + L
Sbjct: 417 RSSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLT 476
Query: 620 FNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTG 675
F ++E +D+L ++DG + + ++G + G + P I S+ L+F +D S
Sbjct: 477 FQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSIN 536
Query: 676 KRGFNITFTTFRH-NECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVL 734
K GF + F F+ +EC P R G C++ L T GS +C
Sbjct: 537 KAGFAVNF--FKEVDECSRPN------RGG------------CEQRCLNTLGSYKCSC-- 574
Query: 735 KEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITF 794
+ RCEA CGG LT +G+I SPGWP Y +C W + A Y I + F
Sbjct: 575 -DPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQF 633
Query: 795 DRFKTEVN----YDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSD 850
D F+TE N YD +EVR G T + L G + G++ P+ + S N + + F +D + S
Sbjct: 634 DFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSK 693
Query: 851 IGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPN 910
GF+ + + D C NG + C SG+ L D + +C+
Sbjct: 694 KGFKAHFFS---DKDECSKD----NGGCQQDCVNTFGSYECQCRSGFVLHDNKH-DCK-- 743
Query: 911 FQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFH 970
EA C + +SGTI SP +PD YP+ CTW I ++ G V TF
Sbjct: 744 ----------EAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMD 793
Query: 971 LES----GHDYLLITENGSFTQP-LRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYE 1025
+ES +D+L + + P L + GS+ P P+ A F +RF SD S+ +
Sbjct: 794 IESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMF---LRFYSDNSVQRK 850
Query: 1026 GF 1027
GF
Sbjct: 851 GF 852
Score = 176 bits (447), Expect = 3e-43
Identities = 172/676 (25%), Positives = 263/676 (38%), Gaps = 159/676 (23%)
Query: 35 GTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEED----FDVLSVFDGPPQPE 90
G ++SP +P Y C W I E + L FQSF +E +D L V DG +
Sbjct: 444 GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESS 503
Query: 91 NLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRLPNGIQ 150
L R G++ P I S ++ L L+ +SD +++ GF + C P R G +
Sbjct: 504 TLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF-FKEVDECSRPNR--GGCE 560
Query: 151 QGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQS 210
Q LG Y C+ C G E + R + ACGG L +
Sbjct: 561 QRCLNTLGS---YKCS------------CDPGYELAPD------KRRCEAACGGFLTKLN 599
Query: 211 GIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG----YDFLEVTG--TEGS 264
G I+SP +P EY N +C W ++A I+L F F+ E YDF+EV T S
Sbjct: 600 GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADS 659
Query: 265 SLW--FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVKLMPSK 322
L F G+ P + S N +R+ F SD ++GF A + K SK
Sbjct: 660 KLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKD----------ECSK 709
Query: 323 DNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRIT 382
DN C + G S + C G+ L
Sbjct: 710 DNGG----------------CQQDCVNTFG-----------SYECQCRSGFVLH------ 736
Query: 383 CMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSK 442
D++ C+ CD + SG ITSPN+P +Y + C W I++ P
Sbjct: 737 ------------DNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISS-TPGH 783
Query: 443 VIKLAFEEFDLER----GYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLF 498
+KL F E D+E YD L V DG + VL G+ P+ +++T +M+L F
Sbjct: 784 RVKLTFMEMDIESQPECAYDHLEVFDGRDA--KAPVLGRFCGSKKPEPVLATGSRMFLRF 841
Query: 499 QTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKA 558
+D S G F+ A E GQ
Sbjct: 842 YSDNSVQRKG------------------------------------FQASHATECGGQVR 865
Query: 559 ITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHL 618
+ + +S + G NYP + C W+I+A + L
Sbjct: 866 ADVKTKDLYSHAQFG-----------------DNNYP----GGVDCEWVIVAEEGYGVEL 904
Query: 619 AFNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHST 674
F +VE + +D++ + DG + AP LG + G+ P + S+G ++F +D +
Sbjct: 905 VFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTI 964
Query: 675 GKRGFNITFTTFRHNE 690
K+GF++ +T+ + +
Sbjct: 965 TKKGFHLRYTSTKFQD 980
Score = 176 bits (445), Expect = 5e-43
Identities = 203/839 (24%), Positives = 316/839 (37%), Gaps = 190/839 (22%)
Query: 734 LKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKIT 793
L +G + + +C A CG L +G SP +P Y + C W I PG I +
Sbjct: 305 LSKGDIAQARKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILN 363
Query: 794 F---DRFKTEVN-YDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHS 849
F D +++ + YD +EVRDG APL G + G+++P+ ++ST + L++ F + +
Sbjct: 364 FTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
Query: 850 DIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEP 909
GF YE I G D D G+ S P + P
Sbjct: 424 GKGFFAVYEAIC------------------GGD--------VKKDYGHIQSPNYPDDYRP 457
Query: 910 NFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTF 969
+ +C IQ S G + F F
Sbjct: 458 S-----------KVCIWRIQVSEGFHVGLTFQSFEIER---------------------- 484
Query: 970 HLESGHDYLLITENGSFTQPL-RQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFN 1028
H +DYL + + S + L + G P I + + ++F+SD S++ GF
Sbjct: 485 HDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKS---TSSRLWLKFVSDGSINKAGFA 541
Query: 1029 ITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTL---TFSCFPGYRLEGTARITCLGGRRR 1085
+ F + +++ C P R G + +TL SC PGY L R
Sbjct: 542 VNFFK-EVDECSRPN------RGGCEQRCLNTLGSYKCSCDPGYELAPDKR--------- 585
Query: 1086 LWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFEL 1145
RC A CG +T G++ SP +P Y N CI+ + I L+ FE
Sbjct: 586 -------RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFET 638
Query: 1146 SEGDVLK-----VYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFE 1200
DV K V G ++L G F SE V + S +++ ++F +D + KGF+
Sbjct: 639 EGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFK 697
Query: 1201 LHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTW 1260
HF S + DE C + GS E C SG
Sbjct: 698 AHFFSDK-----------------DECSKDNGGCQQDC---VNTFGSYECQCRSG-FVLH 736
Query: 1261 DRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTE 1320
D A C V SG + SP +P Y C W I + G + L F+ D E
Sbjct: 737 DNKHDCKEAGCDHKVT-STSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIE 795
Query: 1321 E----VHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQ 1376
+D L ++DG +L G P+ + +T + + L+F +D ++G
Sbjct: 796 SQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKG---- 851
Query: 1377 FSVSTATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQP 1436
F S AT C G ++ + + +F
Sbjct: 852 FQASHATEC----------------------------GGQVRADVKTKDLYSHAQF---- 879
Query: 1437 SPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP-- 1494
GD P GV +C+W + Y + LVF F +E
Sbjct: 880 ----------GDNNYPGGV--------------DCEWVIVAEEGYGVELVFQTFEVEEET 915
Query: 1495 --GYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYT 1551
GYD++ ++DG DS +P +G + GS P + S+ +S+ + F SD +++ GF + YT
Sbjct: 916 DCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYT 974
Score = 172 bits (435), Expect = 7e-42
Identities = 137/484 (28%), Positives = 204/484 (42%), Gaps = 73/484 (15%)
Query: 1269 AECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE----VHD 1324
A CGG V+ + G + SP YP Y + CIW I+ G +GL F F+ E +D
Sbjct: 433 AICGGDVKKDY-GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 1325 VLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQF--SVSTA 1382
L + DG ES L+ G P D+ ST + + L+F +D +K GFA+ F V
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 1383 TSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCI 1442
+ N G Q + S++ CDPGY L P C
Sbjct: 552 SRPNRGGCEQRCLNTLGSYKCS------CDPGYELA-----------------PDKRRCE 588
Query: 1443 APCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPG----YDF 1498
A CGG LT +G I SP +P+ YPP K C W++ Y I+L F+ F E YDF
Sbjct: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
Query: 1499 LHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESC 1558
+ + G + S L G F GS+ P I S N++ + F+SD +VS GF + + E
Sbjct: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECS 708
Query: 1559 FDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAP 1618
D G + G YE + S G + +N A
Sbjct: 709 KDNGGCQQD-------------CVNTFGSYECQCRS---------GFVLHDNKHDCKEAG 746
Query: 1619 CGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALN-------DV 1671
C + + G + SPN+P Y S + C + ++ + V + F + D
Sbjct: 747 CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRV--KLTFMEMDIESQPECAYDH 804
Query: 1672 VEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTS 1731
+EV DG + +L GS E + LAT +++ ++F + +GF +
Sbjct: 805 LEVFDGRDAKAPVLGRFCGSKKPEPV-LATGSRMFLRFYSDNSVQRKGFQ-------ASH 856
Query: 1732 ATQC 1735
AT+C
Sbjct: 857 ATEC 860
Score = 169 bits (428), Expect = 4e-41
Identities = 133/476 (27%), Positives = 206/476 (43%), Gaps = 65/476 (13%)
Query: 1614 VCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFH-----TAL 1668
V A CGG G + SPNYP +Y ++C++ + V + + V F F +
Sbjct: 430 VYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCA 489
Query: 1669 NDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHF-VYQAV 1727
D +EV DGHS+ S L+ G + + +TS+++ +KF + G GF ++ V
Sbjct: 490 YDYLEVRDGHSESSTLIGRYCGYEKPDDIK-STSSRLWLKFVSDGSINKAGFAVNFFKEV 548
Query: 1728 PRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNV 1787
S E R LGS + C+ GY L
Sbjct: 549 DECSRPNRGGC-EQRCLNTLGS-------YKCSCDPGYELAPDKR--------------- 585
Query: 1788 SAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN- 1846
C CGG LT+ G+I SPG+P+ Y + NC+W++V P I +Q F TE N
Sbjct: 586 ---RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGND 642
Query: 1847 ---WDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 1903
+D +EV G + G F G+ P ++ S N + + F SD +VS GF +
Sbjct: 643 VCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF-- 700
Query: 1904 VGLSSCPEPAVPSNGVKTGERYLVNDVVSF--QCEPGYALQGHAHISCMPGTVRRWNYPP 1961
S E + + G ++ VN S+ QC G+ L + H C
Sbjct: 701 --FSDKDECSKDNGGC---QQDCVNTFGSYECQCRSGFVLHDNKH-DCKE---------- 744
Query: 1962 PLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN--- 2018
A C V G I SP +P YPS +C+W I+ G + F+ E
Sbjct: 745 ----AGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPEC 800
Query: 2019 -HDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEY 2073
+D++E+ +G + ++GRF GS+ P +L+T + F+SD+S R GF+ +
Sbjct: 801 AYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
Score = 164 bits (416), Expect = 1e-39
Identities = 211/867 (24%), Positives = 328/867 (37%), Gaps = 238/867 (27%)
Query: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG 85
C L G SP +P GY + +C W I+ +I L F S L
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDL------------ 369
Query: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRL 145
R+RL + DY GF L CG+ +L
Sbjct: 370 ------YRSRLCWY-------------------DYVEVRDGFWRKAP-LRGRFCGS--KL 401
Query: 146 PNGIQQGSTFNLGDKVRYSCNL---GFFLEGHAVLTCHAGSENSATWDFPLPSCRADDAC 202
P I + L + R S N GFF A+ C
Sbjct: 402 PEPIVSTDS-RLWVEFRSSSNWVGKGFFAVYEAI-------------------------C 435
Query: 203 GGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLED----GYDFLEV 258
GG ++ G I SP++P +Y + C W I G + L F F++E YD+LEV
Sbjct: 436 GGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEV 495
Query: 259 TG--TEGSSLW--FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSR 314
+E S+L + G P + S+ + L L F SDG+ + GF+ + K+++ SR
Sbjct: 496 RDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFF--KEVDECSR 553
Query: 315 GVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYD 374
P++ ++ + T LGS + +C+ GY+
Sbjct: 554 -----PNRGGCEQRCLNT----------------------------LGS-YKCSCDPGYE 579
Query: 375 LQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWI 434
L KR C A C L +G ITSP +P +Y N +C+W
Sbjct: 580 LAPDKRR------------------CEAA-CGGFLTKLNGSITSPGWPKEYPPNKNCIWQ 620
Query: 435 ITALNPSKVIKLAFEEFDLERG----YDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVST 490
+ A + I L F+ F+ E YD + V G D K + G+ P++I S
Sbjct: 621 LVAPTQYR-ISLQFDFFETEGNDVCKYDFVEVRSG-LTADSK-LHGKFCGSEKPEVITSQ 677
Query: 491 NHQMWLLFQTDGSGSSLGFKASY----EEI--EQGSCGDPGIPAYGRREGSRFHHGDTLK 544
+ M + F++D + S GFKA + +E + G C + +G E
Sbjct: 678 YNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYE----------- 726
Query: 545 FECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHC 604
+C+ F L +N+ K+ GC TS SG + SPN+P+ Y + C
Sbjct: 727 CQCRSGFVL---------HDNKHDCKEAGCDHKV----TSTSGTITSPNWPDKYPSKKEC 773
Query: 605 VWLILARPESRIHLAFNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQLPSSITSS 660
W I + P R+ L F ++D+E Q +D L + DG A+APVLG F G++ P + ++
Sbjct: 774 TWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLAT 833
Query: 661 GHVARLEFQTDHSTGKRGFNITFTTFRHNEC-PDPGVPVNGKRFGDSLQLGSSISFLCDE 719
G L F +D+S ++GF + T EC V K Q G D
Sbjct: 834 GSRMFLRFYSDNSVQRKGFQASHAT----ECGGQVRADVKTKDLYSHAQFG-------DN 882
Query: 720 GFLGTQGSETITCVLKEG---SVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDAL 776
+ G E + V +EG +V+ + + E CG
Sbjct: 883 NYPGGVDCEWV-IVAEEGYGVELVFQTFEVEEETDCG----------------------- 918
Query: 777 SCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSN 836
+D + YD+ +AP +G Y G+ P+ + S +
Sbjct: 919 -----------------YDYMELFDGYDS---------TAPRLGRYCGSGPPEEVYSAGD 952
Query: 837 YLYLLFSTDKSHSDIGFQLRYETITLQ 863
+ + F +D + + GF LRY + Q
Sbjct: 953 SVLVKFHSDDTITKKGFHLRYTSTKFQ 979
Score = 93.6 bits (231), Expect = 3e-18
Identities = 75/294 (25%), Positives = 125/294 (42%), Gaps = 34/294 (11%)
Query: 2179 EVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SGD 2234
E CGG++ G + SP +P Y S+ C+W I V G V L + E + D
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 2235 FITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGI-FAIAFSAYPLTK 2293
++ + DG +++ +G + ++S+S+++ LKF D + FA+ F + +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
Query: 2294 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEV 2353
C P E N + C PG+ L ++ CE
Sbjct: 551 CSRPN-----RGGCEQRCLNTLGSYKCSCDPGYELAPDK----------------RRCEA 589
Query: 2354 HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEK----QYD 2409
C LT G I S +P YP + C W + Y ISL ++F +E +YD
Sbjct: 590 AC--GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 2410 EFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRY 2463
E+ G + S L G+ P ++TS N++ + + SD+ ++KGFK +
Sbjct: 648 FVEVRSGLTADSKLHGKFCGS-EKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 70.5 bits (171), Expect = 3e-11
Identities = 37/119 (31%), Positives = 61/119 (51%), Gaps = 6/119 (5%)
Query: 17 HHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEED 76
H + AG C ++ +GT+ SP +P YP+ CTW I++ HR++L F +E
Sbjct: 740 HDCKEAG--CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQ 797
Query: 77 ----FDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATY 131
+D L VFDG + R G + P +++ + + LR SD +V +GF A++
Sbjct: 798 PECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
Score = 70.1 bits (170), Expect = 4e-11
Identities = 47/157 (29%), Positives = 74/157 (47%), Gaps = 7/157 (4%)
Query: 529 YGRREGSRFHHGDTL--KFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPS 586
Y R SR DT+ K+E +GQ+ K + A+K +C +
Sbjct: 272 YARNTFSRGIFLDTIVPKYEVNGVKPPIGQRT-RLSKGDIAQARKLYKCPACGETLQDST 330
Query: 587 GVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQ----FDFLVIKDGATAEA 642
G SP YP Y H+HCVW I P +I L F +D+ +D++ ++DG +A
Sbjct: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390
Query: 643 PVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGF 679
P+ G F G++LP I S+ +EF++ + +GF
Sbjct: 391 PLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGF 427
Score = 66.6 bits (161), Expect = 4e-10
Identities = 34/111 (30%), Positives = 58/111 (52%), Gaps = 4/111 (3%)
Query: 1968 CGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIE 2023
CG T+++ G SP +P Y ++M C W+I++ G + F + + +DY+E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 2024 IRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ 2074
+R+G + + + GRF GS+LP ++ST V F S + GF Y+
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE 432
Score = 66.6 bits (161), Expect = 4e-10
Identities = 33/102 (32%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Query: 1987 NYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIEIRNGPYETSRMMGRFSGSE 2042
NYP +DC W I G+G + F F E +DY+E+ +G T+ +GR+ GS
Sbjct: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
Query: 2043 LPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISS 2084
P + S V FHSD + + GF L Y + + S
Sbjct: 943 PPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHS 984
Score = 61.2 bits (147), Expect = 2e-08
Identities = 38/116 (32%), Positives = 54/116 (46%), Gaps = 16/116 (13%)
Query: 201 ACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG----YDFL 256
ACG TL+ +G SSP +P+ Y + C W I G+ I L F L YD++
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 257 EVTGTEGSSLW--------FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQ 304
EV W F G+ LP P++S+ + L + F S N +GF A Y+
Sbjct: 381 EVR----DGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE 432
Score = 59.3 bits (142), Expect = 6e-08
Identities = 43/145 (29%), Positives = 68/145 (46%), Gaps = 11/145 (7%)
Query: 397 RPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERG 456
R + + C L+ +G +SP +P Y + HCVW I ++ P + I L F DL R
Sbjct: 314 RKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRI-SVTPGEKIILNFTSLDLYRS 372
Query: 457 ----YDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKAS 512
YD + V DG + + G+ +P+ IVST+ ++W+ F++ + GF A
Sbjct: 373 RLCWYDYVEVRDG--FWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Query: 513 YEEIEQGSCGDPGIPAYGRREGSRF 537
YE I CG YG + +
Sbjct: 431 YEAI----CGGDVKKDYGHIQSPNY 451
Score = 57.0 bits (136), Expect = 3e-07
Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 4/113 (3%)
Query: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLE 1851
CG L + G SP +P Y ++CVW+I V G I + S ++ +D +E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1852 VFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 1904
V DG + G F G+ +P + ST ++L++ F S + GF Y+ +
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 52.8 bits (125), Expect = 6e-06
Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 7/116 (6%)
Query: 2175 LPKCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSG- 2233
L KC CG + S G SP +P+ YS+ CVW I+V G + LN + L S
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 2234 ---DFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDA--ATGGIFAI 2284
D++ + DG + AP G F S + + S+ +++ ++F + G FA+
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 50.1 bits (118), Expect = 4e-05
Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 13/126 (10%)
Query: 202 CGGTLRGQ---SGIISSPHF-PSEYHNNADCTWTILAELGDTIALVFIDFQLED----GY 253
CGG +R + S F + Y DC W I+AE G + LVF F++E+ GY
Sbjct: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919
Query: 254 DFLEVTGTEGSSL----WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQY-QVKKQ 308
D++E+ S+ + G+ P V S+ + + + F SD ++GF +Y K Q
Sbjct: 920 DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQ 979
Query: 309 IELKSR 314
L SR
Sbjct: 980 DTLHSR 985
Score = 45.4 bits (106), Expect = 0.001
Identities = 35/116 (30%), Positives = 52/116 (44%), Gaps = 6/116 (5%)
Query: 2355 CPT-NELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISL---TVEYFLSEK-QYD 2409
CP E L DSTG S YP Y C W + V P I L +++ + S YD
Sbjct: 319 CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYD 378
Query: 2410 EFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465
E+ DG ++PL G+ P + S+ + +++ + S + KGF Y A
Sbjct: 379 YVEVRDGFWRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Score = 44.3 bits (103), Expect = 0.002
Identities = 31/114 (27%), Positives = 56/114 (49%), Gaps = 6/114 (5%)
Query: 1619 CGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTV-PKDYVV--FGQFAFFHTAL--NDVVE 1673
CG S G SP YP Y++ C++ ++V P + ++ F + + L D VE
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1674 VHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAV 1727
V DG + + L GS E + ++T +++ ++F + +GF VY+A+
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPI-VSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 40.4 bits (93), Expect = 0.031
Identities = 27/94 (28%), Positives = 48/94 (51%), Gaps = 6/94 (6%)
Query: 1117 NYNNNHECIYSIQTQPGKGIQLKARAFELSEG-----DVLKVYDGNNNSARLLGVFSHSE 1171
NY +C + I + G G++L + FE+ E D ++++DG +++A LG + S
Sbjct: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
Query: 1172 MMGVTLNSTSSSLWLDFITDAENTSKGFELHFSS 1205
+ S S+ + F +D T KGF L ++S
Sbjct: 943 -PPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTS 975
Score = 32.7 bits (73), Expect = 6.5
Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 6/92 (6%)
Query: 1638 NYTSGQICLYFVTVPKDYVVFGQFAFFHTALN-----DVVEVHDGHSQHSRLLSSLSGSH 1692
NY G C + + + Y V F F D +E+ DG+ + L GS
Sbjct: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
Query: 1693 TGESLPLATSNQVLIKFSAKGLAPARGFHFVY 1724
E + + + VL+KF + +GFH Y
Sbjct: 943 PPEEV-YSAGDSVLVKFHSDDTITKKGFHLRY 973
>gi|157419154 selectin P precursor [Homo sapiens]
Length = 830
Score = 215 bits (548), Expect = 5e-55
Identities = 157/580 (27%), Positives = 228/580 (39%), Gaps = 55/580 (9%)
Query: 2651 PTCRII-SCGELPIPPN-----GHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLW 2704
P C + CGEL +P + H +G S + + F C GY + G EC+A+G+W
Sbjct: 192 PECEYVRECGELELPQHVLMNCSHPLGNFS-FNSQCSFHCTDGYQVNGPSKLECLASGIW 250
Query: 2705 SGSEVRCLAGHCGTPEPIVNGHI----NGENYSYRGSVVYQCNAGFRLIGMSVRICQQDH 2760
+ +CLA C + G++ + + + ++ S + C GF L+G V C
Sbjct: 251 TNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG 310
Query: 2761 HWSGKTPFCVLVSCGHPGSPPHSQMSG----DSYTVGAVVRYSCIGKRTLVGNSTRMCGL 2816
W+ P C V C H +P M ++ G+ ++ C + G C
Sbjct: 311 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID 370
Query: 2817 DGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGD----SFDPGTVMRFSCEAGHVLRGSSE 2872
GHW+ LP C S C P HG +F T F C G +LRG+
Sbjct: 371 SGHWSAPLPTCEAIS---CEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADI 427
Query: 2873 RTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSD---GLVFSSSIVYECREGYYATGL 2929
C G W+ P C + C + P+ ARV S + S + C EG G
Sbjct: 428 VRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGA 487
Query: 2930 LSRHCSVNGTWTGSDPECLVINCGDPGIPANGLR-----LGNDFRYNKTVTYQCVPGYMM 2984
C G W PEC I C P NG LG+ Y T + C GY +
Sbjct: 488 SVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSS-SYKSTCQFICDEGYSL 546
Query: 2985 ESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSD----FMWGSSVTYACLE 3040
L CT+ W + P+C+A+ C G + SD F GS+ ++C
Sbjct: 547 SGPER--LDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDN 604
Query: 3041 GYQLSLPAVFTCEGNGSWTGELPQCFPVFC-GDPGV-------PSRG----RREDRGFSY 3088
G++L P C +G W+ P C + PGV P +G R F +
Sbjct: 605 GFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGF 664
Query: 3089 RSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQ-- 3146
++ F C+ L+G C+ G W+ P+C C++ V + N S
Sbjct: 665 NTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPAC---RAVKCSELHVNKPIAMNCSNLW 721
Query: 3147 -GYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDC 3185
+ GS F C +G LL GS C N WS T P C
Sbjct: 722 GNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 761
Score = 210 bits (535), Expect = 2e-53
Identities = 165/623 (26%), Positives = 242/623 (38%), Gaps = 54/623 (8%)
Query: 2547 YTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRW 2606
YT + M +G L+ T C +C + P ++ H
Sbjct: 159 YTASCQDMSCSKQGECLETIGNYTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLG 218
Query: 2607 RLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPN 2666
F +Q F C GY G + C A+G W+ + P C C L IP
Sbjct: 219 NFSFNSQCSFH------CTDGYQVNGPSKLECLASGIWT--NKPPQCLAAQCPPLKIPER 270
Query: 2667 GHRIGTLSV----YGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPI 2722
G+ S + ++ FSC G+ LVG V +C A+G+W+ C A C E
Sbjct: 271 GNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAP 330
Query: 2723 VNGHINGEN----YSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPG 2778
G ++ + ++Y S ++C G+R+ G+ + C HWS P C +SC
Sbjct: 331 SEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLE 390
Query: 2779 SPPHSQM----SGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGV 2834
SP H M S ++ + C L G C G WT P C
Sbjct: 391 SPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQ--- 447
Query: 2835 CGDPGIPAHGIRLGDSFDPG-----TVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECG 2889
C D +P + R+ S G +V F+C G +L G+S C A G+W+ PEC
Sbjct: 448 CQDLPVP-NEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQ 506
Query: 2890 VISCGNPGTPSNARVVFSDGL---VFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPE 2946
I C +P N + L + S+ + C EGY +G C+ +G WT S P
Sbjct: 507 AIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPM 566
Query: 2947 CLVINCGDPGIPANGLRLGND----FRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNG 3002
C I C + P G +D F T + C G+ +E + + CT W+
Sbjct: 567 CEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEG--PNNVECTTSGRWSA 624
Query: 3003 TKPVCKALMCKPPPLI--PNGKVVGSDFMW----------GSSVTYACLEGYQLSLPAVF 3050
T P CK + P P + P G M+ ++ + C G+ L +
Sbjct: 625 TPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTL 684
Query: 3051 TCEGNGSWTGELPQCFPVFCGD----PGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSP 3106
+C +G WT P C V C + + FSY S SF C +L GS
Sbjct: 685 SCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSA 744
Query: 3107 RRFCQSDGTWSGTQPSCIDPTLT 3129
+ CQ +G WS T P+C LT
Sbjct: 745 QTACQENGHWSTTVPTCQAGPLT 767
Score = 201 bits (512), Expect = 8e-51
Identities = 172/652 (26%), Positives = 249/652 (38%), Gaps = 77/652 (11%)
Query: 2640 ANGKWS----LGDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSG-YTLVGSR 2694
A GKW+ L C SC ++ G + T+ Y SC G Y
Sbjct: 141 APGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTC----SCYPGFYGPECEY 196
Query: 2695 VRECMANGLWSGSEVRCLAGHCGTPEPIVNG--HINGENYSYRGSVVYQCNAGFRLIGMS 2752
VREC G P+ ++ H G N+S+ + C G+++ G S
Sbjct: 197 VREC---------------GELELPQHVLMNCSHPLG-NFSFNSQCSFHCTDGYQVNGPS 240
Query: 2753 VRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQM----SGDSYTVGAVVRYSCIGKRTLVG 2808
C W+ K P C+ C P M S ++ + +SC LVG
Sbjct: 241 KLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVG 300
Query: 2809 NSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHG----IRLGDSFDPGTVMRFSCEAG 2864
C G WT P C C P+ G + +F G+ +F C+ G
Sbjct: 301 PEVVQCTASGVWTAPAPVCKAVQ---CQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPG 357
Query: 2865 HVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGL---VFSSSIVYECR 2921
+ +RG C +G WS P C ISC +P + + S L + ++ + C
Sbjct: 358 YRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCA 417
Query: 2922 EGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLG-----NDFRYNKTVTY 2976
EG+ G C G WT P C + C D +P N R+ FRY ++
Sbjct: 418 EGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVP-NEARVNCSHPFGAFRYQSVCSF 476
Query: 2977 QCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKV-----VGSDFMWG 3031
C G ++ SVL C WN P C+A+ C P NG + +GS +
Sbjct: 477 TCNEGLLLVG--ASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSS-SYK 533
Query: 3032 SSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGR---REDRG-FS 3087
S+ + C EGY LS P C +G WT P C + C + P +G + RG F+
Sbjct: 534 STCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFN 593
Query: 3088 YRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCID-----------PTLTTCADPGV 3136
S+ FSC L G C + G WS T P+C P LTT PG
Sbjct: 594 VGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTT---PGQ 650
Query: 3137 PQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETP 3196
+++ + +T F C G+ L G +T +C P+ W+ P C C +
Sbjct: 651 GTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVN 710
Query: 3197 THANVGALDLP---SMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPIC 3245
+ +L S G + C EG L GS C+ +G W+ P C
Sbjct: 711 KPIAMNCSNLWGNFSYGSICSFHCLEG-QLLNGSAQTACQENGHWSTTVPTC 761
Score = 181 bits (458), Expect = 1e-44
Identities = 143/527 (27%), Positives = 207/527 (39%), Gaps = 59/527 (11%)
Query: 2767 PFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPH 2826
P VL++C HP +++ + + C + G S C G WT P
Sbjct: 206 PQHVLMNCSHPLG---------NFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQ 256
Query: 2827 CSGTSVGVCGDPGIPAHG----IRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWS 2882
C C IP G + +F + FSCE G L G C A+G W+
Sbjct: 257 CLAAQ---CPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWT 313
Query: 2883 GSQPECGVISCGNPGTPSNARVVFSDGLV---FSSSIVYECREGYYATGLLSRHCSVNGT 2939
P C + C + PS + L + SS +EC+ GY GL C +G
Sbjct: 314 APAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGH 373
Query: 2940 WTGSDPECLVINCGDPGIPANG-------LRLGNDFRYNKTVTYQCVPGYMMESHRVSVL 2992
W+ P C I+C P +G LR F+Y+ +++C G+M+ ++
Sbjct: 374 WSAPLPTCEAISCEPLESPVHGSMDCSPSLRA---FQYDTNCSFRCAEGFMLRG--ADIV 428
Query: 2993 SCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSD-----FMWGSSVTYACLEGYQLSLP 3047
C W PVC+AL C+ P +PN V F + S ++ C EG L
Sbjct: 429 RCDNLGQWTAPAPVCQALQCQDLP-VPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGA 487
Query: 3048 AVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGR----REDRGFSYRSSVSFSCHPPLVLV 3103
+V C G+W P+C + C P G + SY+S+ F C L
Sbjct: 488 SVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLS 547
Query: 3104 GSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQG---YQVGSTVLFRCQK 3160
G R C G W+ + P C C + P+ G + S + VGST F C
Sbjct: 548 GPERLDCTRSGRWTDSPPMC---EAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDN 604
Query: 3161 GYLLQGSTTRTCLPNLTWSGTPPDC-----VPH---HCRQPETPTHANVGALDLP-SMGY 3211
G+ L+G C + WS TPP C +P C TP + P + G+
Sbjct: 605 GFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGF 664
Query: 3212 --TLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRPIN 3256
T + C GF+L G S +C+ G WT P C V+ S +N
Sbjct: 665 NTTCYFGCNAGFTLIGDST-LSCRPSGQWTAVTPACRAVKCSELHVN 710
Score = 175 bits (443), Expect = 8e-43
Identities = 127/496 (25%), Positives = 199/496 (40%), Gaps = 51/496 (10%)
Query: 2486 QPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFG- 2544
Q S F C G+ LVG + CT +W+ P+C+A+ C EAP G +
Sbjct: 283 QHQSSCSFSCEEGFALVGPEVVQCTASG----VWTAPAPVCKAVQCQHLEAPSEGTMDCV 338
Query: 2545 ---KEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVP-PQCVPVTCPDVSSIS 2600
+ G+ + C GY ++ G + C+D+G WS P P C ++C + S
Sbjct: 339 HPLTAFAYGSSCKFECQPGYRVR-GLD-MLRCIDSGHWS---APLPTCEAISCEPLE--S 391
Query: 2601 VEHGRWRLIFETQ-YQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCG 2659
HG + +Q+ C G+ G ++RC G+W+ P C+ + C
Sbjct: 392 PVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTA--PAPVCQALQCQ 449
Query: 2660 ELPIPPNGHRIGTLSVYGA-----TAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAG 2714
+LP+ PN R+ +GA F+CN G LVG+ V +C+A G W+ C A
Sbjct: 450 DLPV-PNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAI 508
Query: 2715 HCGTPEPIVNGHING----ENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCV 2770
C NG + + SY+ + + C+ G+ L G C + W+ P C
Sbjct: 509 PCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCE 568
Query: 2771 LVSCGHPGSPPHSQM----SGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPH 2826
+ C +P + + + VG+ +SC L G + C G W+ + P
Sbjct: 569 AIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPT 628
Query: 2827 CSGTSVGVCGDPGI-------PAHGIRL----GDSFDPGTVMRFSCEAGHVLRGSSERTC 2875
C G + PG+ P G +F T F C AG L G S +C
Sbjct: 629 CKG--IASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSC 686
Query: 2876 QANGSWSGSQPECGVISCG----NPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLS 2931
+ +G W+ P C + C N N ++ + + S + C EG G
Sbjct: 687 RPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGN-FSYGSICSFHCLEGQLLNGSAQ 745
Query: 2932 RHCSVNGTWTGSDPEC 2947
C NG W+ + P C
Sbjct: 746 TACQENGHWSTTVPTC 761
Score = 149 bits (376), Expect = 5e-35
Identities = 124/466 (26%), Positives = 196/466 (42%), Gaps = 42/466 (9%)
Query: 2488 GGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMV----F 2543
G S F C GYR+ G M C G+ WS +P C+A+SC E+P +G +
Sbjct: 347 GSSCKFECQPGYRVRGLDMLRCI--DSGH--WSAPLPTCEAISCEPLESPVHGSMDCSPS 402
Query: 2544 GKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEH 2603
+ + T + C+EG+ L+ GA+ C + G W+ P C + C D+ +
Sbjct: 403 LRAFQYDTNCSFRCAEGFMLR-GAD-IVRCDNLGQWT--APAPVCQALQCQDLPVPNEAR 458
Query: 2604 GRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPI 2663
F +++Q+ C+ G G V++C A G W+ P C+ I C L
Sbjct: 459 VNCSHPFGA-FRYQSVCSFTCNEGLLLVGASVLQCLATGNWN--SVPPECQAIPCTPLLS 515
Query: 2664 PPNG-----HRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGT 2718
P NG +G+ S Y +T F C+ GY+L G +C +G W+ S C A C
Sbjct: 516 PQNGTMTCVQPLGS-SSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPE 574
Query: 2719 PEPIVNGHIN-----GENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCV-LV 2772
G ++ GE ++ + + C+ GF+L G + C WS P C +
Sbjct: 575 LFAPEQGSLDCSDTRGE-FNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIA 633
Query: 2773 SCGHPG-------SPPHSQM----SGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWT 2821
S PG +P M ++ + C TL+G+ST C G WT
Sbjct: 634 SLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWT 693
Query: 2822 GSLPHCSGTSVG-VCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGS 2880
P C + + I + L +F G++ F C G +L GS++ CQ NG
Sbjct: 694 AVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGH 753
Query: 2881 WSGSQPEC--GVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGY 2924
WS + P C G ++ T V + GL+ +++ R+ +
Sbjct: 754 WSTTVPTCQAGPLTIQEALTYFGGAVASTIGLIMGGTLLALLRKRF 799
Score = 115 bits (288), Expect = 8e-25
Identities = 72/244 (29%), Positives = 105/244 (43%), Gaps = 15/244 (6%)
Query: 3027 DFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGR----RE 3082
+F + S ++ C +GYQ++ P+ C +G WT + PQC C +P RG
Sbjct: 219 NFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHS 278
Query: 3083 DRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQ 3142
+ F ++SS SFSC LVG C + G W+ P C P
Sbjct: 279 AKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCV 338
Query: 3143 NNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVG 3202
+ + GS+ F CQ GY ++G C+ + WS P C C E+P H G
Sbjct: 339 HPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVH---G 395
Query: 3203 ALDL-PSM-----GYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRPI- 3255
++D PS+ + C EGF L+G R C G WT P+C ++ P+
Sbjct: 396 SMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVR-CDNLGQWTAPAPVCQALQCQDLPVP 454
Query: 3256 NTAR 3259
N AR
Sbjct: 455 NEAR 458
Score = 75.5 bits (184), Expect = 9e-13
Identities = 140/622 (22%), Positives = 203/622 (32%), Gaps = 161/622 (25%)
Query: 690 ECPDPGVPVNGK----RFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAV 745
+CP +P G + Q SS SF C+EGF G E + C S VW +
Sbjct: 261 QCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGF-ALVGPEVVQCT---ASGVWTAPA 316
Query: 746 LRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDT 805
C+A HL +PS + P A + E QPGY ++ D
Sbjct: 317 PVCKAVQCQHLEAPSEGTMDCVHP-LTAFAYGSSCKFECQPGYRVR----------GLDM 365
Query: 806 LEVRDGRTYSA-----------PLIGVYHGT-----QVPQFLISTSNYL-----YLLFST 844
L D +SA PL HG+ + F T+ ++L
Sbjct: 366 LRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGA 425
Query: 845 DKSHSDIGFQLRYETITLQSDHCLDPGIP----VNGQRHGNDFYVGALVTFSCDSGYTLS 900
D D Q Q+ C D +P VN F ++ +F+C+ G L
Sbjct: 426 DIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLV 485
Query: 901 DGEPLECEPNFQWSRALPSCEAL-CGGFIQGSSGTI--LSPGFPDFYPNNLNCTWIIETS 957
L+C W+ P C+A+ C + +GT+ + P Y + C +I +
Sbjct: 486 GASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKS--TCQFICDEG 543
Query: 958 HGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFI 1017
+ SG + L T +G +T + P
Sbjct: 544 YSL------------SGPERLDCTRSGRWTDSPPMCEAIKCP------------------ 573
Query: 1018 SDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARI 1077
+L E+ + R +F VG T FSC G++LEG +
Sbjct: 574 -----------------ELFAPEQGSLDCSDTRG--EFNVGSTCHFSCDNGFKLEGPNNV 614
Query: 1078 TCLGGRRRLWSSPLPRCV---------AECGNSVTGTQGTLLSPNFPVNYNNNHECIYSI 1128
C R WS+ P C +C T QGT+ + P + N C
Sbjct: 615 ECTTSGR--WSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTC---- 668
Query: 1129 QTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDF 1188
Y G N L+G TL+ S W
Sbjct: 669 -------------------------YFGCNAGFTLIG--------DSTLSCRPSGQW-TA 694
Query: 1189 ITDAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFA-GSSVSFSCDPGYSLRGS 1247
+T A K ELH + + C + G+F+ GS SF C G L GS
Sbjct: 695 VTPACRAVKCSELHVNKPIAMNCSNLW-----------GNFSYGSICSFHCLEGQLLNGS 743
Query: 1248 EELLCLSGERRTWDRPLPTCVA 1269
+ C E W +PTC A
Sbjct: 744 AQTAC--QENGHWSTTVPTCQA 763
Score = 72.4 bits (176), Expect = 7e-12
Identities = 151/664 (22%), Positives = 228/664 (34%), Gaps = 157/664 (23%)
Query: 1024 YEGFNITFSEYDLEPCEEPEVPAYSIRKGLQ----FGVGDTLTFSCFPGYRLEGTARITC 1079
Y GF EY E C E E+P + + F +F C GY++ G +++ C
Sbjct: 186 YPGFYGPECEYVRE-CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLEC 244
Query: 1080 LGGRRRLWSSPLPRCVA-ECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQL 1138
L +W++ P+C+A +C P + N C++S
Sbjct: 245 LASG--IWTNKPPQCLAAQC-------------PPLKIPERGNMTCLHS----------- 278
Query: 1139 KARAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKG 1198
A+AF+ +G L+G + T+S +W T K
Sbjct: 279 -AKAFQHQSSCSFSCEEG----FALVGP--------EVVQCTASGVW----TAPAPVCKA 321
Query: 1199 FELHFSSFELIKCEDPGTPKFGYK--VHDEGHFA-GSSVSFSCDPGYSLRGSEELLCLSG 1255
++C+ P G VH FA GSS F C PGY +RG + L C+
Sbjct: 322 ----------VQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDS 371
Query: 1256 ERRTWDRPLPTCVAECGGTVRGEVSGQV-LSPGYPAPYEHNLNCIWTIEAEAGCTIGLHF 1314
W PLPTC A + V G + SP A ++++ NC + C G F
Sbjct: 372 GH--WSAPLPTCEAISCEPLESPVHGSMDCSPSLRA-FQYDTNCSFR------CAEG--F 420
Query: 1315 LVFDTEEVH-DVLRIW--DGPVESGVLLKELSGPALPK-DLHSTFNSVVLQFSTDFFTSK 1370
++ + V D L W PV + ++L P + + F + Q F ++
Sbjct: 421 MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNE 480
Query: 1371 QGFAIQFSV---------------STATSCNDPGIPQNGSRSG----DSWEAGDSTVFQC 1411
+ SV A C PQNG+ + S + F C
Sbjct: 481 GLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFIC 540
Query: 1412 DPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGP-SGVILSPNYPEPYPPGKE 1470
D GY+L G + C + W SPP C A +L P G + + + G
Sbjct: 541 DEGYSLSGPERLDCTRSGR---WTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGST 597
Query: 1471 CDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNS 1530
C + N F LE + GR S +P
Sbjct: 598 CHFSCD-----------NGFKLEGPNNVECTTSGRWSATP-------------------- 626
Query: 1531 LFLAFRSDASVSNAGFVIDYTENPRESCF----DPGSIKNGTRVGSDLKLGSSVTYY--C 1584
+ AS+ G P + PG+ G + T Y C
Sbjct: 627 --PTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGT------------FGFNTTCYFGC 672
Query: 1585 HGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTA-PCGGQYVGSDGVVLSPNYPQNYTSGQ 1643
+ G+ + G STLSC P G+ W P C A C +V + N N++ G
Sbjct: 673 NAGFTLIGDSTLSC--RPSGQ--WTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGS 728
Query: 1644 ICLY 1647
IC +
Sbjct: 729 ICSF 732
Score = 56.6 bits (135), Expect = 4e-07
Identities = 98/466 (21%), Positives = 158/466 (33%), Gaps = 60/466 (12%)
Query: 1573 DLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVC-TAPCGGQYVGSDGVVL 1631
+ S +++C GY+V G S L C+ +W N P C A C + G +
Sbjct: 219 NFSFNSQCSFHCTDGYQVNGPSKLECL----ASGIWTNKPPQCLAAQCPPLKIPERGNMT 274
Query: 1632 SPNYPQNYTSGQICLY-----FVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLS 1686
+ + + C + F V + V + TA V + +
Sbjct: 275 CLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVW-TAPAPVCKAVQCQHLEAPSEG 333
Query: 1687 SLSGSHTGESLPLATSNQVLIK--FSAKGLAPARGFHFVYQA--VPRTSATQCSSVPEPR 1742
++ H + +S + + + +GL R + + +P A C + P
Sbjct: 334 TMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPV 393
Query: 1743 YGKRLGSD----FSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGG 1798
+G S F F C G+ L+G+ + C L QW AP C
Sbjct: 394 HGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRC----DNLGQWTAPAPVCQALQCQ 449
Query: 1799 NL---TERRGTILSP--GFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVF 1853
+L E R P F + S C +++ + V+ + NW+S+
Sbjct: 450 DLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLL-----VGASVLQCLATGNWNSVPPE 504
Query: 1854 DGADNTVTMLGSFSGT-TVPALLNSTSNQLYLHFYSDISVSAAG-FHLEYKTVG------ 1905
A +L +GT T L S+S + F D S +G L+ G
Sbjct: 505 CQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSP 564
Query: 1906 ----LSSCPEPAVPSNGV----KTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRW 1957
CPE P G T + V F C+ G+ L+G ++ C T RW
Sbjct: 565 PMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECT--TSGRW 622
Query: 1958 NYPPPLCI---------AQCGGTVEEMEGVILSPGFPGNYPSNMDC 1994
+ PP C QC +G + PG + N C
Sbjct: 623 SATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTC 668
Score = 52.8 bits (125), Expect = 6e-06
Identities = 57/240 (23%), Positives = 73/240 (30%), Gaps = 66/240 (27%)
Query: 343 CPDPGIPERGKRL----GSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRP 398
CP IPERG F+ SS F+C EG+ L G + + C W+ P
Sbjct: 262 CPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQC----TASGVWTAPAP 317
Query: 399 VCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYD 458
VC+A C HL PS + CV +TA K + RG D
Sbjct: 318 VCKAVQCQ-HLEAPS------------EGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLD 364
Query: 459 TLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQ 518
L D G + A E
Sbjct: 365 MLRCIDSGH-----------------------------------------WSAPLPTCEA 383
Query: 519 GSCGDPGIPAYGRREGS----RFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGC 574
SC P +G + S F + F C F L G + C QW+A P C
Sbjct: 384 ISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVC 443
Score = 52.8 bits (125), Expect = 6e-06
Identities = 98/441 (22%), Positives = 139/441 (31%), Gaps = 102/441 (23%)
Query: 149 IQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRG 208
+ F +SC GF L G V+ C A S W P P C+A
Sbjct: 276 LHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTA----SGVWTAPAPVCKA---------- 321
Query: 209 QSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDF--LEVTGTEGSSL 266
+ H + DC + A + F+ + GY L++ S
Sbjct: 322 ----VQCQHLEAPSEGTMDCVHPLTAFAYGSSC----KFECQPGYRVRGLDMLRCIDSGH 373
Query: 267 WFTGASLPAPVISSKNWLR--LHFTSDGNHRQRGFSAQYQVKKQIELKS----RGVKLMP 320
W A LP S L +H + D + R F QY RG ++
Sbjct: 374 W--SAPLPTCEAISCEPLESPVHGSMDCSPSLRAF--QYDTNCSFRCAEGFMLRGADIVR 429
Query: 321 SKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSD----FRLGSSVQFTCNEGYDLQ 376
+ Q T+ Q C D +P + S FR S FTCNEG L
Sbjct: 430 CDNLGQWTAPAPVCQALQ----CQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLV 485
Query: 377 GSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIIT 436
G+ + C+ + W+ P C+A C L +G +T CV +
Sbjct: 486 GASVLQCLATGN----WNSVPPECQAIPCTPLLSPQNGTMT-------------CVQPLG 528
Query: 437 ALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWL 496
+ + +F + GY S P+ + T W
Sbjct: 529 SSSYKSTC-----QFICDEGY----------------------SLSGPERLDCTRSGRW- 560
Query: 497 LFQTDGSGSSLGFKA-SYEEIEQGS--CGDPGIPAYGRREGSRFHHGDTLKFECQPAFEL 553
TD K EQGS C D F+ G T F C F+L
Sbjct: 561 ---TDSPPMCEAIKCPELFAPEQGSLDCSD---------TRGEFNVGSTCHFSCDNGFKL 608
Query: 554 VGQKAITCQKNNQWSAKKPGC 574
G + C + +WSA P C
Sbjct: 609 EGPNNVECTTSGRWSATPPTC 629
Score = 46.2 bits (108), Expect = 6e-04
Identities = 57/260 (21%), Positives = 99/260 (38%), Gaps = 40/260 (15%)
Query: 155 FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQSGIIS 214
F+ + + C G+ + G + L C A S W P C A C + G ++
Sbjct: 220 FSFNSQCSFHCTDGYQVNGPSKLECLA----SGIWTNKPPQCLAAQ-CPPLKIPERGNMT 274
Query: 215 SPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFL--EVTGTEGSSLWFTGAS 272
H + + + C+ F E+G+ + EV S +W +
Sbjct: 275 CLHSAKAFQHQSSCS-----------------FSCEEGFALVGPEVVQCTASGVW----T 313
Query: 273 LPAPVISSKNWLRLHFTSDGN----HRQRGFSAQYQVKKQIE--LKSRGVKLMPSKDNSQ 326
PAPV + L S+G H F+ K + + + RG+ ++ D+
Sbjct: 314 APAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGH 373
Query: 327 KTSVL-TQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMK 385
++ L T +S P G + L + F+ ++ F C EG+ L+G+ + C
Sbjct: 374 WSAPLPTCEAISCEPLESPVHGSMDCSPSLRA-FQYDTNCSFRCAEGFMLRGADIVRC-- 430
Query: 386 VSDMFAAWSDHRPVCRARMC 405
D W+ PVC+A C
Sbjct: 431 --DNLGQWTAPAPVCQALQC 448
Score = 43.1 bits (100), Expect = 0.005
Identities = 137/630 (21%), Positives = 213/630 (33%), Gaps = 144/630 (22%)
Query: 1224 HDEGHFA-GSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVA-ECGGTVRGEVSG 1281
H G+F+ S SF C GY + G +L CL+ W P C+A +C
Sbjct: 215 HPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASG--IWTNKPPQCLAAQC---------- 262
Query: 1282 QVLSPGYPAPYEHNLNCIWTIEA---EAGCTIGLH--FLVFDTEEVHDVLR-IWDGP--V 1333
P P N+ C+ + +A ++ C+ F + E V +W P V
Sbjct: 263 ----PPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPV 318
Query: 1334 ESGVLLKELSGPALPKDLHSTFNSV-----VLQFSTDFFTSKQGFAIQ------------ 1376
V + L P+ T + V S+ F + G+ ++
Sbjct: 319 CKAVQCQHLEAPS-----EGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGH 373
Query: 1377 ----FSVSTATSCNDPGIPQNGSR----SGDSWEAGDSTVFQCDPGYALQGSAEISCVKI 1428
A SC P +GS S +++ + F+C G+ L+G+ + C
Sbjct: 374 WSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRC--- 430
Query: 1429 ENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYP-EPYPPGKECDWK-----VTVSPDYV 1482
+N W P C A DL P+ ++ ++P + C + + V +
Sbjct: 431 DNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVL 490
Query: 1483 IALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVS 1542
L +N P LSP G+ Q G SSS F D S
Sbjct: 491 QCLATGNWNSVPPE--CQAIPCTPLLSPQNGTMTCVQPLG---SSSYKSTCQFICDEGYS 545
Query: 1543 NAGFV-IDYTENPRESCFDP---------------GSIKNGTRVGSDLKLGSSVTYYCHG 1586
+G +D T + R + P GS+ G + +GS+ + C
Sbjct: 546 LSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRG-EFNVGSTCHFSCDN 604
Query: 1587 GYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICL 1646
G+++EG + + C G+ W+ P C G + + GV P T GQ +
Sbjct: 605 GFKLEGPNNVECTTS--GR--WSATPPTCK---GIASLPTPGV----QCPALTTPGQGTM 653
Query: 1647 YFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVL 1706
Y P G F F T G + G +L
Sbjct: 654 YCRHHP------GTFGFNTTCY--------------------FGCNAGFTL--------- 678
Query: 1707 IKFSAKGLAPARGFHFVYQAVPRTSATQCSSV----PEPRYGKRLGSDFSVGAIVRFECN 1762
I S P+ + V P A +CS + P L +FS G+I F C
Sbjct: 679 IGDSTLSCRPSGQWTAV---TPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCL 735
Query: 1763 SGYALQGSPEIECLPVPGALAQWNVSAPTC 1792
G L GS + C W+ + PTC
Sbjct: 736 EGQLLNGSAQTAC----QENGHWSTTVPTC 761
Score = 43.1 bits (100), Expect = 0.005
Identities = 46/226 (20%), Positives = 71/226 (31%), Gaps = 63/226 (27%)
Query: 358 DFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIIT 417
+F S F C +GY + G ++ C+ W++ P C A C
Sbjct: 219 NFSFNSQCSFHCTDGYQVNGPSKLECLASG----IWTNKPPQCLAAQC------------ 262
Query: 418 SPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYI 477
P I N C+ A + EE +
Sbjct: 263 -PPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEG------------------------FA 297
Query: 478 LTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREG--- 534
L G P+++ T +W A + C P+ G +
Sbjct: 298 LVG---PEVVQCTASGVWT--------------APAPVCKAVQCQHLEAPSEGTMDCVHP 340
Query: 535 -SRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGC-VFSC 578
+ F +G + KFECQP + + G + C + WSA P C SC
Sbjct: 341 LTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISC 386
Score = 43.1 bits (100), Expect = 0.005
Identities = 41/136 (30%), Positives = 51/136 (37%), Gaps = 23/136 (16%)
Query: 2078 YSHQIS---SFLRGFDLSELERTNSTPPVAASYVWDLD-PGCEAYELQECPDPEPFANGI 2133
+ HQ S S GF L E T AS VW P C+A + Q P
Sbjct: 282 FQHQSSCSFSCEEGFALVGPEVVQCT----ASGVWTAPAPVCKAVQCQHLEAPSEGTMDC 337
Query: 2134 VRG-AGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSSNGT 2192
V + G S FEC PGY++ G +L C + +W PLP CE
Sbjct: 338 VHPLTAFAYGSSCKFECQPGYRVRGLDMLRCI--DSGHWSAPLPTCE------------A 383
Query: 2193 VYSPGFPSPYSSSQDC 2208
+ SP S DC
Sbjct: 384 ISCEPLESPVHGSMDC 399
Score = 41.6 bits (96), Expect = 0.014
Identities = 43/162 (26%), Positives = 61/162 (37%), Gaps = 20/162 (12%)
Query: 2088 GFDLSELERTNSTPPVAASYVW-DLDPGCEAYELQECPDPEPFANGIVRGAG-YNVGQSV 2145
G+ LS ER + T S W D P CEA + E PE + G +NVG +
Sbjct: 543 GYSLSGPERLDCT----RSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTC 598
Query: 2146 TFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCE---------VPCGGNITSSNGTVYSP 2196
F C G++L G + C T+ W P C+ V C T GT+Y
Sbjct: 599 HFSCDNGFKLEGPNNVECT--TSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCR 656
Query: 2197 GFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITI 2238
P + + C + + S L PSG + +
Sbjct: 657 HHPGTFGFNTTCYFGCNAGF---TLIGDSTLSCRPSGQWTAV 695
Score = 38.1 bits (87), Expect = 0.15
Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 8/63 (12%)
Query: 343 CPDPGIPERGKRLGSD----FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRP 398
CP+ PE+G SD F +GS+ F+C+ G+ L+G + C WS P
Sbjct: 572 CPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVEC----TTSGRWSATPP 627
Query: 399 VCR 401
C+
Sbjct: 628 TCK 630
Score = 38.1 bits (87), Expect = 0.15
Identities = 15/46 (32%), Positives = 21/46 (45%)
Query: 529 YGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGC 574
Y R F T F C F L+G ++C+ + QW+A P C
Sbjct: 654 YCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPAC 699
Score = 36.6 bits (83), Expect = 0.45
Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 13/82 (15%)
Query: 2311 EFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICE---------VHCPTNELL 2361
EFN+G + C GF L G + C T ++ PP C+ V CP L
Sbjct: 591 EFNVGSTCHFSCDNGFKLEGPNNVECT--TSGRWSATPPTCKGIASLPTPGVQCPA--LT 646
Query: 2362 TDSTGVILSQSYPGSYPQFQTC 2383
T G + + +PG++ TC
Sbjct: 647 TPGQGTMYCRHHPGTFGFNTTC 668
Score = 32.3 bits (72), Expect = 8.4
Identities = 21/81 (25%), Positives = 30/81 (37%), Gaps = 11/81 (13%)
Query: 155 FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDA-------CGGTLR 207
FN+G +SC+ GF LEG + C S W P+C+ + C
Sbjct: 592 FNVGSTCHFSCDNGFKLEGPNNVEC----TTSGRWSATPPTCKGIASLPTPGVQCPALTT 647
Query: 208 GQSGIISSPHFPSEYHNNADC 228
G + H P + N C
Sbjct: 648 PGQGTMYCRHHPGTFGFNTTC 668
Score = 32.3 bits (72), Expect = 8.4
Identities = 16/45 (35%), Positives = 20/45 (44%), Gaps = 4/45 (8%)
Query: 154 TFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRA 198
TF + CN GF L G + L+C S W P+CRA
Sbjct: 661 TFGFNTTCYFGCNAGFTLIGDSTLSCRP----SGQWTAVTPACRA 701
>gi|22547221 tolloid-like 1 [Homo sapiens]
Length = 1013
Score = 213 bits (541), Expect = 3e-54
Identities = 189/683 (27%), Positives = 282/683 (41%), Gaps = 159/683 (23%)
Query: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEED----FDVLS 81
C ++ G ++SP +P Y C W IT E + + L FQSF +E +D L
Sbjct: 462 CGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLE 521
Query: 82 VFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGN 141
V DG + L R G+ P I S + TL ++ +SD V+ GF A + C
Sbjct: 522 VRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF-FKEEDECAK 580
Query: 142 PGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDA 201
P R G +Q LG Y C C G E SC A A
Sbjct: 581 PDR--GGCEQRCLNTLGS---YQC------------ACEPGYELGP----DRRSCEA--A 617
Query: 202 CGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG----YDFLE 257
CGG L +G I++P +P EY N +C W ++A I++ F F+LE YD++E
Sbjct: 618 CGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVE 677
Query: 258 V-TGTEGSSLW---FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKS 313
+ +G S F GA +P + S N +R+ F SD ++GF A + K K
Sbjct: 678 IWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKD 737
Query: 314 RGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGY 373
G Q V T G MC C G+
Sbjct: 738 NG--------GCQHECVNT-----MGSYMC------------------------QCRNGF 760
Query: 374 DLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVW 433
L D++ C+ C+ + PSG+ITSPN+P +Y + C W
Sbjct: 761 VLH------------------DNKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTW 802
Query: 434 IITALNPSKVIKLAFEEFDLER----GYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVS 489
I+A P IKLAF EF++E+ YD L V DG + ++ +L L G +PD +V+
Sbjct: 803 EISA-TPGHRIKLAFSEFEIEQHQECAYDHLEVFDG--ETEKSPILGRLCGNKIPDPLVA 859
Query: 490 TNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQP 549
T ++M++ F +D S GF+A++ CG GR LK E +P
Sbjct: 860 TGNKMFVRFVSDASVQRKGFQATHST----ECG-------GR-----------LKAESKP 897
Query: 550 AFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLIL 609
+ +S + G NYP + C WL++
Sbjct: 898 --------------RDLYSHAQFG-----------------DNNYP----GQVDCEWLLV 922
Query: 610 ARPESRIHLAFNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVAR 665
+ SR+ L+F +VE + +D++ + DG + A LG F G+ P I S G
Sbjct: 923 SERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVL 982
Query: 666 LEFQTDHSTGKRGFNITFTTFRH 688
+ F TD + K+GF+I + + R+
Sbjct: 983 IHFHTDDTINKKGFHIRYKSIRY 1005
Score = 202 bits (513), Expect = 6e-51
Identities = 169/652 (25%), Positives = 268/652 (41%), Gaps = 124/652 (19%)
Query: 1269 AECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE----VHD 1324
A CGG +R GQ+ SP YP Y C+W I +GL F F+ E +D
Sbjct: 460 AICGGEIRKN-EGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYD 518
Query: 1325 VLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATS 1384
L + DG E+ L+ G P+D+ ST N++ ++F +D +K GFA F
Sbjct: 519 YLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF-FKEEDE 577
Query: 1385 CNDP---GIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC 1441
C P G Q + S++ C+PGY L P +C
Sbjct: 578 CAKPDRGGCEQRCLNTLGSYQCA------CEPGYELG-----------------PDRRSC 614
Query: 1442 IAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPG----YD 1497
A CGG LT +G I +P +P+ YPP K C W+V Y I++ F F LE YD
Sbjct: 615 EAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYD 674
Query: 1498 FLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRES 1557
++ I+ G S S L G F G+++P I S N++ + F+SD +VS GF + + E
Sbjct: 675 YVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDEC 734
Query: 1558 CFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTA 1617
D G + H G+ C +G + +N A
Sbjct: 735 SKDNGGCQ-------------------HECVNTMGSYMCQC---RNGFVLHDNKHDCKEA 772
Query: 1618 PCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALN-----DVV 1672
C + G++ SPN+P Y S + C + ++ + + F+ F + D +
Sbjct: 773 ECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHL 832
Query: 1673 EVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSA 1732
EV DG ++ S +L L G+ + L +AT N++ ++F + +GF T +
Sbjct: 833 EVFDGETEKSPILGRLCGNKIPDPL-VATGNKMFVRFVSDASVQRKGFQ-------ATHS 884
Query: 1733 TQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC 1792
T+C G RL ++ + + AQ+ +
Sbjct: 885 TEC--------GGRLKAESKPRDLY-----------------------SHAQFGDNNYPG 913
Query: 1793 VVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEV 1852
V C L RG+ L F Q V + +D +E+
Sbjct: 914 QVDCEWLLVSERGSRLELSF----------------------QTFEVEEEADCGYDYVEL 951
Query: 1853 FDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 1904
FDG D+T LG F G+ P + S + + +HF++D +++ GFH+ YK++
Sbjct: 952 FDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKSI 1003
Score = 200 bits (509), Expect = 2e-50
Identities = 135/468 (28%), Positives = 219/468 (46%), Gaps = 55/468 (11%)
Query: 404 MCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLER----GYDT 459
+C +R G I SPN+P Y CVW IT ++ S + L F+ F++ER YD
Sbjct: 461 ICGGEIRKNEGQIQSPNYPDDYRPMKECVWKIT-VSESYHVGLTFQSFEIERHDNCAYDY 519
Query: 460 LTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQG 519
L V DG + ++ G P+ I ST++ +W+ F +DG+ + GF A++ + E+
Sbjct: 520 LEVRDG--TSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFK-EED 576
Query: 520 SCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCF 579
C P R G Q +G C+ + + C +C
Sbjct: 577 ECAKPD------RGGCE-----------QRCLNTLGSYQCACEPGYELGPDRRSCEAACG 619
Query: 580 FNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEP----QFDFLVIK 635
T +G + +P +P++Y + +CVW ++A + RI + F ++E ++D++ I
Sbjct: 620 GLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIW 679
Query: 636 DGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPG 695
G ++E+ + G F G ++P ITS + R+EF++D++ K+GF F + + D G
Sbjct: 680 SGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNG 739
Query: 696 VPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGH 755
C + T GS C + G V+ ++ EA C
Sbjct: 740 G--------------------CQHECVNTMGSYMCQC--RNGFVLHDNKHDCKEAECEQK 777
Query: 756 LTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN----YDTLEVRDG 811
+ SPSG I SP WP Y C W I A PG+ IK+ F F+ E + YD LEV DG
Sbjct: 778 IHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDG 837
Query: 812 RTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYET 859
T +P++G G ++P L++T N +++ F +D S GFQ + T
Sbjct: 838 ETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHST 885
Score = 196 bits (497), Expect = 4e-49
Identities = 176/688 (25%), Positives = 274/688 (39%), Gaps = 165/688 (23%)
Query: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLE 1851
CGG + + G I SP +P+ Y CVWKI V E + + SF E++ +D LE
Sbjct: 462 CGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLE 521
Query: 1852 VFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPE 1911
V DG ++G F G P + STSN L++ F SD +V+ AGF + E
Sbjct: 522 VRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF----FKEEDE 577
Query: 1912 PAVPSNGVKTGERYLVNDVVSFQC--EPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCG 1969
A P G E+ +N + S+QC EPGY L G RR C A CG
Sbjct: 578 CAKPDRG--GCEQRCLNTLGSYQCACEPGYEL----------GPDRR------SCEAACG 619
Query: 1970 GTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIEIR 2025
G + ++ G I +PG+P YP N +C W++ P + ++F F E N +DY+EI
Sbjct: 620 GLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIW 679
Query: 2026 NGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSF 2085
+G S++ G+F G+E+P + S + + F SD++ ++ GFK +
Sbjct: 680 SGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFS---------- 729
Query: 2086 LRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQSV 2145
D E + N GC+ EC N S
Sbjct: 730 ----DKDECSKDNG--------------GCQ----HEC---------------VNTMGSY 752
Query: 2146 TFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSPYSSS 2205
+C G+ L D+ E C I S +G + SP +P Y S
Sbjct: 753 MCQCRNGFVL---------------HDNKHDCKEAECEQKIHSPSGLITSPNWPDKYPSR 797
Query: 2206 QDCVWLITVPIGHGVRLNLSLLQTEP----SGDFITIWDGPQQTAPRLGVFTRSMAKKTV 2261
++C W I+ GH ++L S + E + D + ++DG + +P LG + +
Sbjct: 798 KECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIPDPL 857
Query: 2262 QSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYR 2321
++ N++ ++F DA+ + F A T+C
Sbjct: 858 VATGNKMFVRFVSDAS---VQRKGFQATHSTEC--------------------------- 887
Query: 2322 CLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQ 2381
G L+ E P H + +YPG
Sbjct: 888 -----------------GGRLKAESKPRDLYSHAQFGD-----------NNYPGQV---- 915
Query: 2382 TCSWLVRVEPDYNISLTVEYFLSEKQ----YDEFEIFDGPSGQSPLLKALSGNYSAPLIV 2437
C WL+ E + L+ + F E++ YD E+FDG + L G+ P +
Sbjct: 916 DCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGS-GPPEEI 974
Query: 2438 TSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465
S +SV + + +D N+KGF IRY +
Sbjct: 975 YSIGDSVLIHFHTDDTINKKGFHIRYKS 1002
Score = 191 bits (486), Expect = 8e-48
Identities = 177/667 (26%), Positives = 278/667 (41%), Gaps = 125/667 (18%)
Query: 559 ITCQKNNQWSAKKPGCVFS--CFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRI 616
I + ++ W K V+ C G + SPNYP+DY CVW I +
Sbjct: 441 IEFRSSSNWVGKGFAAVYEAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHV 500
Query: 617 HLAFNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDH 672
L F ++E +D+L ++DG + +P++G F G P I S+ + ++F +D
Sbjct: 501 GLTFQSFEIERHDNCAYDYLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDG 560
Query: 673 STGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITC 732
+ K GF F +EC P R G C++ L T GS C
Sbjct: 561 TVNKAGFAANFFK-EEDECAKPD------RGG------------CEQRCLNTLGSYQCAC 601
Query: 733 VLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKI 792
E CEA CGG LT +GTI +PGWP Y +C W + A Y I +
Sbjct: 602 ---EPGYELGPDRRSCEAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISV 658
Query: 793 TFDRFKTEVN----YDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSH 848
F+ F+ E N YD +E+ G + + L G + G +VP+ + S N + + F +D +
Sbjct: 659 KFEFFELEGNEVCKYDYVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTV 718
Query: 849 SDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECE 908
S GF+ + + D C G +H +G+ + C +G+ L D + +C+
Sbjct: 719 SKKGFKAHFFS---DKDECSKDN---GGCQHECVNTMGSYMC-QCRNGFVLHDNKH-DCK 770
Query: 909 PNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHT 968
EA C I SG I SP +PD YP+ CTW I + G + F
Sbjct: 771 ------------EAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSE 818
Query: 969 F----HLESGHDYLLITENGSFTQP-LRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMS 1023
F H E +D+L + + + P L +L G+++P P+ A F VRF+SD S+
Sbjct: 819 FEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMF---VRFVSDASVQ 875
Query: 1024 YEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGR 1083
RKG Q T S G RL+ ++
Sbjct: 876 --------------------------RKGFQ------ATHSTECGGRLKAESK------P 897
Query: 1084 RRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAF 1143
R L+S A+ G++ NY +C + + ++ G ++L + F
Sbjct: 898 RDLYSH------AQFGDN---------------NYPGQVDCEWLLVSERGSRLELSFQTF 936
Query: 1144 ELSEG-----DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKG 1198
E+ E D ++++DG +++A LG F S + S S+ + F TD KG
Sbjct: 937 EVEEEADCGYDYVELFDGLDSTAVGLGRFCGSG-PPEEIYSIGDSVLIHFHTDDTINKKG 995
Query: 1199 FELHFSS 1205
F + + S
Sbjct: 996 FHIRYKS 1002
Score = 179 bits (453), Expect = 6e-44
Identities = 135/472 (28%), Positives = 211/472 (44%), Gaps = 63/472 (13%)
Query: 1614 VCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALND--- 1670
V A CGG+ ++G + SPNYP +Y + C++ +TV + Y V F F +D
Sbjct: 457 VYEAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCA 516
Query: 1671 --VVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVP 1728
+EV DG S++S L+ G E + +TSN + +KF + G GF +
Sbjct: 517 YDYLEVRDGTSENSPLIGRFCGYDKPEDIR-STSNTLWMKFVSDGTVNKAGFAANFFKEE 575
Query: 1729 RTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVS 1788
A E R LGS + C GY L
Sbjct: 576 DECAKPDRGGCEQRCLNTLGS-------YQCACEPGYEL------------------GPD 610
Query: 1789 APTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN-- 1846
+C CGG LT+ GTI +PG+P+ Y + NCVW++V P I ++ F E N
Sbjct: 611 RRSCEAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEV 670
Query: 1847 --WDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 1904
+D +E++ G + + G F G VP ++ S N + + F SD +VS GF +
Sbjct: 671 CKYDYVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHF--- 727
Query: 1905 GLSSCPEPAVPSNGVKTGERYLVNDVVSF--QCEPGYALQGHAHISCMPGTVRRWNYPPP 1962
S E + + G + VN + S+ QC G+ L + H C
Sbjct: 728 -FSDKDECSKDNGGC---QHECVNTMGSYMCQCRNGFVLHDNKH-DCKE----------- 771
Query: 1963 LCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN---- 2018
A+C + G+I SP +P YPS +C+W+I+ G + F F E +
Sbjct: 772 ---AECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECA 828
Query: 2019 HDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFK 2070
+D++E+ +G E S ++GR G+++P L++T ++ V F SD S R GF+
Sbjct: 829 YDHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQ 880
Score = 175 bits (444), Expect = 6e-43
Identities = 168/645 (26%), Positives = 268/645 (41%), Gaps = 119/645 (18%)
Query: 749 EAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN----YD 804
EA CGG + G I SP +P Y+ C W I Y + +TF F+ E + YD
Sbjct: 459 EAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYD 518
Query: 805 TLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQS 864
LEVRDG + ++PLIG + G P+ + STSN L++ F +D + + GF + +
Sbjct: 519 YLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFK---EE 575
Query: 865 DHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALC 924
D C P QR N L ++ C CEP ++ SCEA C
Sbjct: 576 DECAKPDRGGCEQRCLN-----TLGSYQC------------ACEPGYELGPDRRSCEAAC 618
Query: 925 GGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESG----HDYLLI 980
GG + +GTI +PG+P YP N NC W + + F F LE +DY+ I
Sbjct: 619 GGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEI 678
Query: 981 TENGSFTQPLR-QLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPC 1039
S L + G+ +P I++ + N ++ F SD ++S +GF F D + C
Sbjct: 679 WSGLSSESKLHGKFCGAEVPEVITS-QFNNM--RIEFKSDNTVSKKGFKAHFFS-DKDEC 734
Query: 1040 EEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECG 1099
+ G Q +T+ G+ C G L + AEC
Sbjct: 735 SKD-------NGGCQHECVNTM-----------GSYMCQCRNG-FVLHDNKHDCKEAECE 775
Query: 1100 NSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEG-----DVLKVY 1154
+ G + SPN+P Y + EC + I PG I+L FE+ + D L+V+
Sbjct: 776 QKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVF 835
Query: 1155 DGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSS--FELIKCE 1212
DG + +LG +++ L +T + +++ F++DA KGF+ S+ +K E
Sbjct: 836 DGETEKSPILGRLCGNKIPD-PLVATGNKMFVRFVSDASVQRKGFQATHSTECGGRLKAE 894
Query: 1213 DPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECG 1272
+ + + ++ G C+ W V+E G
Sbjct: 895 SKPRDLYSHAQFGDNNYPG---QVDCE--------------------W-----LLVSERG 926
Query: 1273 GTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGP 1332
R E+S Q + +E EA C +D + ++DG
Sbjct: 927 S--RLELSFQT----------------FEVEEEADCG-------------YDYVELFDGL 955
Query: 1333 VESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQF 1377
+ V L G P++++S +SV++ F TD +K+GF I++
Sbjct: 956 DSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRY 1000
Score = 167 bits (423), Expect = 2e-40
Identities = 135/513 (26%), Positives = 216/513 (42%), Gaps = 102/513 (19%)
Query: 1966 AQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDY 2021
A CGG + + EG I SP +P +Y +C WKI + + + F +F E + +DY
Sbjct: 460 AICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDY 519
Query: 2022 IEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQ 2081
+E+R+G E S ++GRF G + P + STS+ + F SD + N+ GF
Sbjct: 520 LEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGF------------ 567
Query: 2082 ISSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNV 2141
AA++ + D EC P+ G N
Sbjct: 568 ----------------------AANFFKEED---------ECAKPD---RGGCEQRCLNT 593
Query: 2142 GQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSP 2201
S C PGY+L G +R CE CGG +T NGT+ +PG+P
Sbjct: 594 LGSYQCACEPGYEL----------GPDRR------SCEAACGGLLTKLNGTITTPGWPKE 637
Query: 2202 YSSSQDCVWLITVPIGHGVRLNLSLLQTEPSG----DFITIWDGPQQTAPRLGVFTRSMA 2257
Y +++CVW + P + + + + E + D++ IW G + G F +
Sbjct: 638 YPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWSGLSSESKLHGKFCGAEV 697
Query: 2258 KKTVQSSSNQVLLKFHRD--AATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIG 2315
+ + S N + ++F D + G A FS +C ++E N
Sbjct: 698 PEVITSQFNNMRIEFKSDNTVSKKGFKAHFFS--DKDEC------SKDNGGCQHECVNTM 749
Query: 2316 DIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPG 2375
+C GF L N+ CK Q ++H P +G+I S ++P
Sbjct: 750 GSYMCQCRNGFVLHDNK-HDCKEAECEQ--------KIHSP--------SGLITSPNWPD 792
Query: 2376 SYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQ----YDEFEIFDGPSGQSPLLKALSGNY 2431
YP + C+W + P + I L F E+ YD E+FDG + +SP+L L GN
Sbjct: 793 KYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGN- 851
Query: 2432 SAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYS 2464
P + ++ N +++R+ SD + RKGF+ +S
Sbjct: 852 KIPDPLVATGNKMFVRFVSDASVQRKGFQATHS 884
Score = 166 bits (419), Expect = 5e-40
Identities = 169/689 (24%), Positives = 262/689 (38%), Gaps = 177/689 (25%)
Query: 202 CGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLED----GYDFLE 257
CGG +R G I SP++P +Y +C W I + L F F++E YD+LE
Sbjct: 462 CGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLE 521
Query: 258 VTG--TEGSSLW--FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKS 313
V +E S L F G P + S+ N L + F SDG + GF+A +
Sbjct: 522 VRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF---------- 571
Query: 314 RGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGY 373
+D K P+RG S Q C GY
Sbjct: 572 -----FKEEDECAK---------------------PDRGGCEQRCLNTLGSYQCACEPGY 605
Query: 374 DLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVW 433
+L +R C A C L +G IT+P +P +Y N +CVW
Sbjct: 606 ELGPDRRS------------------CEAA-CGGLLTKLNGTITTPGWPKEYPPNKNCVW 646
Query: 434 IITALNPSKVIKLAFEEFDLERG----YDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVS 489
+ A + I + FE F+LE YD + + G + + G VP++I S
Sbjct: 647 QVVAPTQYR-ISVKFEFFELEGNEVCKYDYVEIWSGLSSESKLHGKFC--GAEVPEVITS 703
Query: 490 TNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQP 549
+ M + F++D + S GFKA + + D G + EC
Sbjct: 704 QFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNG----------------GCQHEC-- 745
Query: 550 AFELVGQKAITCQKNNQWSAKKPGCVFS-CFFNFTSPSGVVLSPNYPEDYGNHLHCVWLI 608
+G C+ K C + C SPSG++ SPN+P+ Y + C W I
Sbjct: 746 -VNTMGSYMCQCRNGFVLHDNKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEI 804
Query: 609 LARPESRIHLAFNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVA 664
A P RI LAF++ ++E +D L + DG T ++P+LG GN++P
Sbjct: 805 SATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIP---------- 854
Query: 665 RLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCD-----E 719
DP V K F + F+ D +
Sbjct: 855 ----------------------------DPLVATGNKMF---------VRFVSDASVQRK 877
Query: 720 GFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGF----YKDA 775
GF T +E CGG L + S F Y
Sbjct: 878 GFQATHSTE-----------------------CGGRLKAESKPRDLYSHAQFGDNNYPGQ 914
Query: 776 LSCAWVIEAQPGYPIKITFDRFKTE----VNYDTLEVRDGRTYSAPLIGVYHGTQVPQFL 831
+ C W++ ++ G ++++F F+ E YD +E+ DG +A +G + G+ P+ +
Sbjct: 915 VDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEI 974
Query: 832 ISTSNYLYLLFSTDKSHSDIGFQLRYETI 860
S + + + F TD + + GF +RY++I
Sbjct: 975 YSIGDSVLIHFHTDDTINKKGFHIRYKSI 1003
Score = 117 bits (293), Expect = 2e-25
Identities = 100/367 (27%), Positives = 153/367 (41%), Gaps = 43/367 (11%)
Query: 20 RSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEED--- 76
RS C L NGT+ +PG+P YP NC W + A Q+RI + F+ F LE +
Sbjct: 612 RSCEAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVC 671
Query: 77 -FDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLP 135
+D + ++ G L + G ++P I S + + SD VS +GF A +
Sbjct: 672 KYDYVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHF-FSD 730
Query: 136 SHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
C NG Q N C GF L +
Sbjct: 731 KDECSK----DNGGCQHECVNTMGSYMCQCRNGFVLHDNK------------------HD 768
Query: 196 CRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLED---- 251
C+ + C + SG+I+SP++P +Y + +CTW I A G I L F +F++E
Sbjct: 769 CK-EAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQEC 827
Query: 252 GYDFLEVTG--TEGSSLW--FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKK 307
YD LEV TE S + G +P P++++ N + + F SD + +++GF A + +
Sbjct: 828 AYDHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHSTEC 887
Query: 308 QIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQF 367
LK+ SK + G C + ERG RL F+ V+
Sbjct: 888 GGRLKAE------SKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQT-FEVEE 940
Query: 368 TCNEGYD 374
+ GYD
Sbjct: 941 EADCGYD 947
Score = 104 bits (260), Expect = 1e-21
Identities = 81/294 (27%), Positives = 122/294 (41%), Gaps = 34/294 (11%)
Query: 2179 EVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SGD 2234
E CGG I + G + SP +P Y ++CVW ITV + V L + E + D
Sbjct: 459 EAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYD 518
Query: 2235 FITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKC 2294
++ + DG + +P +G F + ++S+SN + +KF D A +C
Sbjct: 519 YLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDEC 578
Query: 2295 PPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPP-PICEV 2353
P E N + C PG+ L GP CE
Sbjct: 579 AKPD-----RGGCEQRCLNTLGSYQCACEPGYEL-----------------GPDRRSCEA 616
Query: 2354 HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEK----QYD 2409
C LLT G I + +P YP + C W V Y IS+ E+F E +YD
Sbjct: 617 AC--GGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYD 674
Query: 2410 EFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRY 2463
EI+ G S +S L G P ++TS N++ + + SD+ ++KGFK +
Sbjct: 675 YVEIWSGLSSESKLHGKFCG-AEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHF 727
Score = 75.1 bits (183), Expect = 1e-12
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 1968 CGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIE 2023
CG T++E G + SPGFP YPS C W++++ G + F + +DYIE
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 2024 IRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ 2074
+R+G + S ++GRF G +LP L ST + F S + GF Y+
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYE 459
Score = 74.3 bits (181), Expect = 2e-12
Identities = 43/131 (32%), Positives = 67/131 (51%), Gaps = 5/131 (3%)
Query: 734 LKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKIT 793
L +G + + RC A CG L +G + SPG+P Y C W + PG I +
Sbjct: 332 LSKGDIAQARKLYRCPA-CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLN 390
Query: 794 F---DRFKTEVN-YDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHS 849
F D +K+ + YD +EVRDG +PL+G + G ++P+ L ST + +++ F + +
Sbjct: 391 FTTMDLYKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWV 450
Query: 850 DIGFQLRYETI 860
GF YE I
Sbjct: 451 GKGFAAVYEAI 461
Score = 69.7 bits (169), Expect = 5e-11
Identities = 37/110 (33%), Positives = 57/110 (51%), Gaps = 4/110 (3%)
Query: 1445 CGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPG----YDFLH 1500
CG L +G + SP +P YP C W+V+V+P I L F +L YD++
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 1501 IYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDY 1550
+ DG SPL+G F G +LP + S+ + +++ FRS ++ GF Y
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVY 458
Score = 65.1 bits (157), Expect = 1e-09
Identities = 34/113 (30%), Positives = 57/113 (50%), Gaps = 4/113 (3%)
Query: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLE 1851
CG L E G + SPGFP Y + +C+W++ V G I + + ++ +D +E
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 1852 VFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 1904
V DG +LG F G +P +L ST +++++ F S + GF Y+ +
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAI 461
Score = 65.1 bits (157), Expect = 1e-09
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Query: 1987 NYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIEIRNGPYETSRMMGRFSGSE 2042
NYP +DC W + G + F F E +DY+E+ +G T+ +GRF GS
Sbjct: 910 NYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSG 969
Query: 2043 LPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTY 2078
P + S ++FH+D + N+ GF + Y+ + Y
Sbjct: 970 PPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKSIRY 1005
Score = 64.7 bits (156), Expect = 2e-09
Identities = 30/107 (28%), Positives = 58/107 (54%), Gaps = 4/107 (3%)
Query: 577 SCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQ----FDFL 632
+C +G + SP +P Y ++ HC+W + P +I L F +D+ +D++
Sbjct: 348 ACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYI 407
Query: 633 VIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGF 679
++DG ++P+LG F G++LP +TS+ +EF++ + +GF
Sbjct: 408 EVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGF 454
Score = 62.8 bits (151), Expect = 6e-09
Identities = 38/124 (30%), Positives = 63/124 (50%), Gaps = 7/124 (5%)
Query: 397 RPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERG 456
R + R C L+ +G ++SP FP Y + HC+W + ++ P + I L F DL +
Sbjct: 341 RKLYRCPACGETLQESNGNLSSPGFPNGYPSYTHCIWRV-SVTPGEKIVLNFTTMDLYKS 399
Query: 457 ----YDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKAS 512
YD + V DG + +L G +P+++ ST+ +MW+ F++ + GF A
Sbjct: 400 SLCWYDYIEVRDG--YWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAV 457
Query: 513 YEEI 516
YE I
Sbjct: 458 YEAI 461
Score = 62.4 bits (150), Expect = 8e-09
Identities = 40/134 (29%), Positives = 59/134 (44%), Gaps = 8/134 (5%)
Query: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEED----FDVLS 81
C L NG + SPGFP GYP+Y +C W ++ +I L F + L + +D +
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 82 VFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGN 141
V DG + L R G +LP + S + + + S +GF A YE + CG
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAI----CGG 464
Query: 142 PGRLPNGIQQGSTF 155
R G Q +
Sbjct: 465 EIRKNEGQIQSPNY 478
Score = 59.3 bits (142), Expect = 6e-08
Identities = 38/114 (33%), Positives = 57/114 (50%), Gaps = 7/114 (6%)
Query: 1091 LPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEG-- 1148
L RC A CG ++ + G L SP FP Y + CI+ + PG+ I L +L +
Sbjct: 343 LYRCPA-CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSL 401
Query: 1149 ---DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGF 1199
D ++V DG + LLG F ++ V L ST S +W++F + + KGF
Sbjct: 402 CWYDYIEVRDGYWRKSPLLGRFCGDKLPEV-LTSTDSRMWIEFRSSSNWVGKGF 454
Score = 58.5 bits (140), Expect = 1e-07
Identities = 33/112 (29%), Positives = 56/112 (50%), Gaps = 5/112 (4%)
Query: 2182 CGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSG----DFIT 2237
CG + SNG + SPGFP+ Y S C+W ++V G + LN + + S D+I
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 2238 IWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAA-TGGIFAIAFSA 2288
+ DG + +P LG F + + S+ +++ ++F + G FA + A
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEA 460
Score = 56.6 bits (135), Expect = 4e-07
Identities = 38/116 (32%), Positives = 57/116 (49%), Gaps = 6/116 (5%)
Query: 2355 CPT-NELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISL---TVEYFLSEK-QYD 2409
CP E L +S G + S +P YP + C W V V P I L T++ + S YD
Sbjct: 346 CPACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYD 405
Query: 2410 EFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465
E+ DG +SPLL G+ P ++TS+ + +++ + S + KGF Y A
Sbjct: 406 YIEVRDGYWRKSPLLGRFCGD-KLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEA 460
Score = 55.5 bits (132), Expect = 9e-07
Identities = 36/116 (31%), Positives = 53/116 (45%), Gaps = 16/116 (13%)
Query: 201 ACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG----YDFL 256
ACG TL+ +G +SSP FP+ Y + C W + G+ I L F L YD++
Sbjct: 348 ACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYI 407
Query: 257 EVTGTEGSSLW--------FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQ 304
EV W F G LP + S+ + + + F S N +GF+A Y+
Sbjct: 408 EVR----DGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYE 459
Score = 51.6 bits (122), Expect = 1e-05
Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 1262 RPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE 1321
R L C A CG T++ E +G + SPG+P Y +CIW + G I L+F D +
Sbjct: 341 RKLYRCPA-CGETLQ-ESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYK 398
Query: 1322 V----HDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFA 1374
+D + + DG LL G LP+ L ST + + ++F + +GFA
Sbjct: 399 SSLCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFA 455
Score = 50.1 bits (118), Expect = 4e-05
Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 6/96 (6%)
Query: 914 SRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLES 973
+R L C A CG +Q S+G + SPGFP+ YP+ +C W + + G+ + F T L
Sbjct: 340 ARKLYRCPA-CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYK 398
Query: 974 G----HDYLLITENGSFTQP-LRQLTGSRLPAPISA 1004
+DY+ + + P L + G +LP +++
Sbjct: 399 SSLCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTS 434
Score = 47.0 bits (110), Expect = 3e-04
Identities = 35/114 (30%), Positives = 58/114 (50%), Gaps = 6/114 (5%)
Query: 1619 CGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTV-PKDYVV--FGQFAFFHTAL--NDVVE 1673
CG S+G + SP +P Y S C++ V+V P + +V F + ++L D +E
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 1674 VHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAV 1727
V DG+ + S LL G E L +T +++ I+F + +GF VY+A+
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVL-TSTDSRMWIEFRSSSNWVGKGFAAVYEAI 461
>gi|6912724 tolloid-like 2 [Homo sapiens]
Length = 1015
Score = 206 bits (525), Expect = 3e-52
Identities = 185/687 (26%), Positives = 284/687 (41%), Gaps = 163/687 (23%)
Query: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLE 1851
CGG++ + G I SP +P+ Y S CVW+I V EG + + +F E++ +D LE
Sbjct: 464 CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLE 523
Query: 1852 VFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPE 1911
V DG ++G F G P + S+SN+L++ F SD S++ AGF + E
Sbjct: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF----FKEVDE 579
Query: 1912 PAVPSNGVKTGERYLVNDVVSFQC--EPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCG 1969
+ P +G E VN + S++C +PGY L +C CG
Sbjct: 580 CSWPDHG--GCEHRCVNTLGSYKCACDPGYELAADKK----------------MCEVACG 621
Query: 1970 GTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIEIR 2025
G + ++ G I SPG+P YP+N +C W++ P + +QF F E N +D++E+R
Sbjct: 622 GFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVR 681
Query: 2026 NGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSF 2085
+G +++ GRF GSE P + S S+ V F SD++ ++ GF+ +
Sbjct: 682 SGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS---------- 731
Query: 2086 LRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQSV 2145
D E + N GC+ EC N S
Sbjct: 732 ----DKDECAKDNG--------------GCQ----HEC---------------VNTFGSY 754
Query: 2146 TFECLPGYQL--TGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSPYS 2203
C GY L GH C+ E C I+S GT+ SP +P Y
Sbjct: 755 LCRCRNGYWLHENGH---DCK--------------EAGCAHKISSVEGTLASPNWPDKYP 797
Query: 2204 SSQDCVWLITVPIGHGVRLNLSLLQTEP----SGDFITIWDGPQQTAPRLGVFTRSMAKK 2259
S ++C W I+ GH V+L + + E + D + ++DGP AP LG F S
Sbjct: 798 SRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPD 857
Query: 2260 TVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVR 2319
+S + + L+F+ DA+ + F A T+C
Sbjct: 858 PTVASGSSMFLRFYSDAS---VQRKGFQAVHSTEC------------------------- 889
Query: 2320 YRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQ 2379
G L E+ T +L ++ QF E C + D GV L+
Sbjct: 890 -----GGRLKA-EVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELT--------- 934
Query: 2380 FQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPL-IVT 2438
F+T + V E D YD E +DG +P L G S PL +
Sbjct: 935 FRT--FEVEEEADCG-------------YDYMEAYDGYDSSAPRLGRFCG--SGPLEEIY 977
Query: 2439 SSSNSVYLRWSSDHAYNRKGFKIRYSA 2465
S+ +S+ +R+ +D N+KGF RY++
Sbjct: 978 SAGDSLMIRFRTDDTINKKGFHARYTS 1004
Score = 195 bits (495), Expect = 8e-49
Identities = 138/464 (29%), Positives = 210/464 (45%), Gaps = 57/464 (12%)
Query: 1096 AECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGD-----V 1150
A CG + G + SPN+P +Y + EC++ I G + L +AFE+ D
Sbjct: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
Query: 1151 LKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIK 1210
L+V DG + L+G F E + S+S+ LW+ F++D GF +F E+ +
Sbjct: 522 LEVRDGPTEESALIGHFCGYEKPE-DVKSSSNRLWMKFVSDGSINKAGFAANFFK-EVDE 579
Query: 1211 CEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAE 1270
C P G H + GS +CDPGY L +++ C
Sbjct: 580 CS---WPDHGGCEHRCVNTLGS-YKCACDPGYELAADKKM----------------CEVA 619
Query: 1271 CGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE----VHDVL 1326
CGG + +++G + SPG+P Y N NC+W + A A I L F VF+ E +D +
Sbjct: 620 CGGFIT-KLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFV 678
Query: 1327 RIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCN 1386
+ G L G P+ + S N++ ++F +D SK+GF F S
Sbjct: 679 EVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFF-----SDK 733
Query: 1387 DPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCG 1446
D NG + S + +C GY L + C + A C
Sbjct: 734 DECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGH-DCKE---------------AGCA 777
Query: 1447 GDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP----GYDFLHIY 1502
++ G + SPN+P+ YP +EC W ++ + + + L FN F +E YD L +Y
Sbjct: 778 HKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMY 837
Query: 1503 DGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGF 1546
DG DSL+P++G F GS+ P +S +S+FL F SDASV GF
Sbjct: 838 DGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF 881
Score = 194 bits (493), Expect = 1e-48
Identities = 180/650 (27%), Positives = 271/650 (41%), Gaps = 129/650 (19%)
Query: 577 SCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQ----FDFL 632
+C + +G + SPNYP+DY CVW I + L F ++E +D+L
Sbjct: 463 TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYL 522
Query: 633 VIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRH-NEC 691
++DG T E+ ++G F G + P + SS + ++F +D S K GF F F+ +EC
Sbjct: 523 EVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF--FKEVDEC 580
Query: 692 --PDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCE 749
PD G C+ + T GS C + + CE
Sbjct: 581 SWPDHGG--------------------CEHRCVNTLGSYKCAC---DPGYELAADKKMCE 617
Query: 750 APCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN----YDT 805
CGG +T +GTI SPGWP Y +C W + A Y I + F+ F+ E N YD
Sbjct: 618 VACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
Query: 806 LEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSD 865
+EVR G + A L G + G++ P+ + S SN + + F +D + S GF+ + + D
Sbjct: 678 VEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS---DKD 734
Query: 866 HCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCG 925
C G +H G+ + C +GY L + +C+ EA C
Sbjct: 735 ECAKDN---GGCQHECVNTFGSYLC-RCRNGYWLHENGH-DCK------------EAGCA 777
Query: 926 GFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTF----HLESGHDYLLIT 981
I GT+ SP +PD YP+ CTW I ++ G V TF+ F H E +D+L +
Sbjct: 778 HKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMY 837
Query: 982 ENGSFTQP-LRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCE 1040
+ P L + GS+ P P A F +RF SD S+
Sbjct: 838 DGPDSLAPILGRFCGSKKPDPTVASGSSMF---LRFYSDASVQ----------------- 877
Query: 1041 EPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGN 1100
RKG Q S G RL+ + + L+S A+ G+
Sbjct: 878 ---------RKGFQ------AVHSTECGGRLKAEVQT------KELYSH------AQFGD 910
Query: 1101 SVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEG-----DVLKVYD 1155
+ NY + C + I + G G++L R FE+ E D ++ YD
Sbjct: 911 N---------------NYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYD 955
Query: 1156 GNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSS 1205
G ++SA LG F S + + S SL + F TD KGF ++S
Sbjct: 956 GYDSSAPRLGRFCGSGPL-EEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
Score = 192 bits (487), Expect = 6e-48
Identities = 130/468 (27%), Positives = 224/468 (47%), Gaps = 57/468 (12%)
Query: 405 CDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLER----GYDTL 460
C + +G I SPN+P Y + CVW IT ++ + L F+ F++ER YD L
Sbjct: 464 CGGDMNKDAGQIQSPNYPDDYRPSKECVWRIT-VSEGFHVGLTFQAFEIERHDSCAYDYL 522
Query: 461 TVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASY-EEIEQG 519
V DG + + ++ G P+ + S+++++W+ F +DGS + GF A++ +E+++
Sbjct: 523 EVRDGPTE--ESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
Query: 520 SCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCF 579
S P +G E + + K C P +EL K + C +C
Sbjct: 581 SW-----PDHGGCEHRCVNTLGSYKCACDPGYELAADKKM--------------CEVACG 621
Query: 580 FNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEP----QFDFLVIK 635
T +G + SP +P++Y + +CVW ++A + RI L F ++E ++DF+ ++
Sbjct: 622 GFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVR 681
Query: 636 DGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPG 695
G + +A + G F G++ P ITS + R+EF++D++ KRGF F + + D G
Sbjct: 682 SGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNG 741
Query: 696 VPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGH 755
C + T GS C + G + + EA C
Sbjct: 742 G--------------------CQHECVNTFGSYLCRC--RNGYWLHENGHDCKEAGCAHK 779
Query: 756 LTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN----YDTLEVRDG 811
++S GT+ SP WP Y C W I + G+ +K+TF+ F+ E + YD LE+ DG
Sbjct: 780 ISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDG 839
Query: 812 RTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYET 859
AP++G + G++ P +++ + ++L F +D S GFQ + T
Sbjct: 840 PDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHST 887
Score = 176 bits (445), Expect = 5e-43
Identities = 168/649 (25%), Positives = 266/649 (40%), Gaps = 125/649 (19%)
Query: 749 EAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN----YD 804
EA CGG + +G I SP +P Y+ + C W I G+ + +TF F+ E + YD
Sbjct: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
Query: 805 TLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQS 864
LEVRDG T + LIG + G + P+ + S+SN L++ F +D S + GF + +
Sbjct: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFK---EV 577
Query: 865 DHCLDPGIPVNGQRHGNDFY--VGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEA 922
D C P HG + V L ++ C C+P ++ + CE
Sbjct: 578 DECSWPD-------HGGCEHRCVNTLGSYKC------------ACDPGYELAADKKMCEV 618
Query: 923 LCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESG----HDYL 978
CGGFI +GTI SPG+P YP N NC W + + F F LE +D++
Sbjct: 619 ACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFV 678
Query: 979 LITENGSFTQPLR-QLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLE 1037
+ S L + GS P I++ + +V F SD ++S GF F D +
Sbjct: 679 EVRSGLSPDAKLHGRFCGSETPEVITS---QSNNMRVEFKSDNTVSKRGFRAHFFS-DKD 734
Query: 1038 PCEEPEVPAYSIRKGLQFGVGDTL---TFSCFPGYRLEGTARITCLGGRRRLWSSPLPRC 1094
C + G Q +T C GY L G
Sbjct: 735 ECAKD-------NGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAG------------ 775
Query: 1095 VAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEG-----D 1149
C + ++ +GTL SPN+P Y + EC ++I + G ++L FE+ + D
Sbjct: 776 ---CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYD 832
Query: 1150 VLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELI 1209
L++YDG ++ A +LG F S+ T+ ++ SS++L F +DA KGF+
Sbjct: 833 HLEMYDGPDSLAPILGRFCGSKKPDPTV-ASGSSMFLRFYSDASVQRKGFQ--------- 882
Query: 1210 KCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVA 1269
VH S + G L+ + L + D P+ A
Sbjct: 883 ------------AVH------------STECGGRLKAEVQTKELYSHAQFGDNNYPS-EA 917
Query: 1270 ECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIW 1329
C + V GY + +E EA C +D + +
Sbjct: 918 RCDWVI-------VAEDGYGVELTFR---TFEVEEEADCG-------------YDYMEAY 954
Query: 1330 DGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFS 1378
DG S L G ++++S +S++++F TD +K+GF +++
Sbjct: 955 DGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYT 1003
Score = 175 bits (443), Expect = 8e-43
Identities = 132/469 (28%), Positives = 205/469 (43%), Gaps = 63/469 (13%)
Query: 1617 APCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFH-----TALNDV 1671
A CGG G + SPNYP +Y + C++ +TV + + V F F + D
Sbjct: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
Query: 1672 VEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTS 1731
+EV DG ++ S L+ G E + ++SN++ +KF + G GF +
Sbjct: 522 LEVRDGPTEESALIGHFCGYEKPEDVK-SSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
Query: 1732 ATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPT 1791
+ E R LGS + C+ GY L ++
Sbjct: 581 SWPDHGGCEHRCVNTLGS-------YKCACDPGYELAADKKM------------------ 615
Query: 1792 CVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----W 1847
C V CGG +T+ GTI SPG+P+ Y + NCVW++V P I +Q F E N +
Sbjct: 616 CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKY 675
Query: 1848 DSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLS 1907
D +EV G + G F G+ P ++ S SN + + F SD +VS GF + S
Sbjct: 676 DFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHF----FS 731
Query: 1908 SCPEPAVPSNGVKTGERYLVNDVVSF--QCEPGYALQGHAHISCMPGTVRRWNYPPPLCI 1965
E A + G + VN S+ +C GY L + H C
Sbjct: 732 DKDECAKDNGGC---QHECVNTFGSYLCRCRNGYWLHENGH-DCKE-------------- 773
Query: 1966 AQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDY 2021
A C + +EG + SP +P YPS +C+W I+ G + F F E + +D+
Sbjct: 774 AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833
Query: 2022 IEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFK 2070
+E+ +GP + ++GRF GS+ P +++ + F+SD S R GF+
Sbjct: 834 LEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQ 882
Score = 167 bits (424), Expect = 1e-40
Identities = 124/469 (26%), Positives = 196/469 (41%), Gaps = 58/469 (12%)
Query: 1269 AECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE----VHD 1324
A CGG + + +GQ+ SP YP Y + C+W I G +GL F F+ E +D
Sbjct: 462 ATCGGDMNKD-AGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
Query: 1325 VLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATS 1384
L + DGP E L+ G P+D+ S+ N + ++F +D +K GFA F
Sbjct: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEV--- 577
Query: 1385 CNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAP 1444
++ P +G S CDPGY L ++ C
Sbjct: 578 -DECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKM-----------------CEVA 619
Query: 1445 CGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPG----YDFLH 1500
CGG +T +G I SP +P+ YP K C W+V Y I+L F +F LE YDF+
Sbjct: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679
Query: 1501 IYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFD 1560
+ G + L G F GS+ P I S SN++ + F+SD +VS GF + + E D
Sbjct: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKD 739
Query: 1561 PGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCG 1620
G ++ + S C GY + N A C
Sbjct: 740 NGGCQH-----ECVNTFGSYLCRCRNGYWLH-----------------ENGHDCKEAGCA 777
Query: 1621 GQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDY---VVFGQFAF--FHTALNDVVEVH 1675
+ +G + SPN+P Y S + C + ++ + + F +F D +E++
Sbjct: 778 HKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMY 837
Query: 1676 DGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVY 1724
DG + +L GS + +A+ + + ++F + +GF V+
Sbjct: 838 DGPDSLAPILGRFCGSKKPDP-TVASGSSMFLRFYSDASVQRKGFQAVH 885
Score = 167 bits (422), Expect = 2e-40
Identities = 135/513 (26%), Positives = 216/513 (42%), Gaps = 102/513 (19%)
Query: 1966 AQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDY 2021
A CGG + + G I SP +P +Y + +C W+I + GF + F F E + +DY
Sbjct: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
Query: 2022 IEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQ 2081
+E+R+GP E S ++G F G E P + S+S+ + F SD S N+ GF
Sbjct: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF------------ 569
Query: 2082 ISSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNV 2141
AA++ ++D EC P+ +G N
Sbjct: 570 ----------------------AANFFKEVD---------ECSWPD---HGGCEHRCVNT 595
Query: 2142 GQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSP 2201
S C PGY+L + CEV CGG IT NGT+ SPG+P
Sbjct: 596 LGSYKCACDPGYELAADKKM----------------CEVACGGFITKLNGTITSPGWPKE 639
Query: 2202 YSSSQDCVWLITVPIGHGVRLNLSLLQTEPSG----DFITIWDGPQQTAPRLGVFTRSMA 2257
Y ++++CVW + P + + L + + E + DF+ + G A G F S
Sbjct: 640 YPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSET 699
Query: 2258 KKTVQSSSNQVLLKFHRD--AATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIG 2315
+ + S SN + ++F D + G A FS E +N
Sbjct: 700 PEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS-------------DKDECAKDNGG---- 742
Query: 2316 DIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPG 2375
++ C+ F G+ + C+ G +L E E C ++ G + S ++P
Sbjct: 743 --CQHECVNTF---GSYLCRCRNGYWLH-ENGHDCKEAGCA--HKISSVEGTLASPNWPD 794
Query: 2376 SYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQ----YDEFEIFDGPSGQSPLLKALSGNY 2431
YP + C+W + + + LT F E+ YD E++DGP +P+L G+
Sbjct: 795 KYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGS- 853
Query: 2432 SAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYS 2464
P +S +S++LR+ SD + RKGF+ +S
Sbjct: 854 KKPDPTVASGSSMFLRFYSDASVQRKGFQAVHS 886
Score = 166 bits (420), Expect = 4e-40
Identities = 167/685 (24%), Positives = 258/685 (37%), Gaps = 159/685 (23%)
Query: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEED----FDVLS 81
C ++ G ++SP +P Y C W IT E + L FQ+F +E +D L
Sbjct: 464 CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLE 523
Query: 82 VFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGN 141
V DGP + L G++ P + S++ L ++ +SD +++ GF A + C
Sbjct: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF-FKEVDECSW 582
Query: 142 PGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDA 201
P G + LG Y C C G E +A + A
Sbjct: 583 PDH--GGCEHRCVNTLGS---YKC------------ACDPGYELAADKKM------CEVA 619
Query: 202 CGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG----YDFLE 257
CGG + +G I+SP +P EY N +C W ++A I+L F F+LE YDF+E
Sbjct: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679
Query: 258 V-TGTEGSSLW---FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKS 313
V +G + F G+ P + S N +R+ F SD +RGF A + K K
Sbjct: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKD 739
Query: 314 RGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGY 373
G Q V T G +C C GY
Sbjct: 740 NG--------GCQHECVNT-----FGSYLC------------------------RCRNGY 762
Query: 374 DLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVW 433
L ++ C+ C + G + SPN+P +Y + C W
Sbjct: 763 WLH------------------ENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTW 804
Query: 434 IITALNPSKVIKLAFEEFDLER----GYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVS 489
I++ +V KL F EF++E+ YD L + DG +L G+ PD V+
Sbjct: 805 NISSTAGHRV-KLTFNEFEIEQHQECAYDHLEMYDG--PDSLAPILGRFCGSKKPDPTVA 861
Query: 490 TNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQP 549
+ M+L F +D S GF+A + CG
Sbjct: 862 SGSSMFLRFYSDASVQRKGFQA----VHSTECG--------------------------- 890
Query: 550 AFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLIL 609
G+ Q +S + G NYP + C W+I+
Sbjct: 891 -----GRLKAEVQTKELYSHAQFG-----------------DNNYPSE----ARCDWVIV 924
Query: 610 ARPESRIHLAFNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVAR 665
A + L F +VE + +D++ DG + AP LG F G+ I S+G
Sbjct: 925 AEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLM 984
Query: 666 LEFQTDHSTGKRGFNITFTTFRHNE 690
+ F+TD + K+GF+ +T+ + +
Sbjct: 985 IRFRTDDTINKKGFHARYTSTKFQD 1009
Score = 139 bits (350), Expect = 5e-32
Identities = 149/573 (26%), Positives = 229/573 (39%), Gaps = 123/573 (21%)
Query: 201 ACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG----YDFL 256
ACG TL+ +G S+P FP+ Y + + C W I G+ I L F L YD++
Sbjct: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
Query: 257 EVTGTEGSSLW--------FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQV--- 305
EV W F G +P P++S+ + L + F S N +GF A Y+
Sbjct: 410 EVR----DGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCG 465
Query: 306 ------KKQIELKSRGVKLMPSKDNSQKTSVLT--QVGVS------QGHNMCPDPGIPER 351
QI+ + PSK+ + +V VG++ + H+ C + R
Sbjct: 466 GDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVR 525
Query: 352 GKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMK-VSD------MFAA----------WS 394
+G + E D++ S MK VSD FAA W
Sbjct: 526 DGPTEESALIGHFCGYEKPE--DVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWP 583
Query: 395 DH---------------------------RPVCRARMCDAHLRGPSGIITSPNFPIQYDN 427
DH + +C C + +G ITSP +P +Y
Sbjct: 584 DHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEV-ACGGFITKLNGTITSPGWPKEYPT 642
Query: 428 NAHCVWIITALNPSKV-IKLAFEEFDLERG----YDTLTVGDGGQDGDQKTVLYILTGTS 482
N +CVW + A P++ I L FE F+LE YD + V G D K + G+
Sbjct: 643 NKNCVWQVVA--PAQYRISLQFEVFELEGNDVCKYDFVEV-RSGLSPDAK-LHGRFCGSE 698
Query: 483 VPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDT 542
P++I S ++ M + F++D + S GF+A + + D G
Sbjct: 699 TPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNG----------------G 742
Query: 543 LKFECQPAFELVGQKAITCQKNNQW------SAKKPGCVFSCFFNFTSPSGVVLSPNYPE 596
+ EC F G C +N W K+ GC +S G + SPN+P+
Sbjct: 743 CQHECVNTF---GSYLCRC-RNGYWLHENGHDCKEAGCA----HKISSVEGTLASPNWPD 794
Query: 597 DYGNHLHCVWLILARPESRIHLAFNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQ 652
Y + C W I + R+ L FN+ ++E +D L + DG + AP+LG F G++
Sbjct: 795 KYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSK 854
Query: 653 LPSSITSSGHVARLEFQTDHSTGKRGFNITFTT 685
P +SG L F +D S ++GF +T
Sbjct: 855 KPDPTVASGSSMFLRFYSDASVQRKGFQAVHST 887
Score = 108 bits (269), Expect = 1e-22
Identities = 80/293 (27%), Positives = 127/293 (43%), Gaps = 32/293 (10%)
Query: 2179 EVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SGD 2234
E CGG++ G + SP +P Y S++CVW ITV G V L + E + D
Sbjct: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
Query: 2235 FITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKC 2294
++ + DGP + + +G F + V+SSSN++ +KF D + A + +C
Sbjct: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
Query: 2295 PPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVH 2354
P E+ N + C PG+ L ++ +CEV
Sbjct: 581 SWPD-----HGGCEHRCVNTLGSYKCACDPGYELAADK----------------KMCEVA 619
Query: 2355 CPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEK----QYDE 2410
C +T G I S +P YP + C W V Y ISL E F E +YD
Sbjct: 620 C--GGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
Query: 2411 FEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRY 2463
E+ G S + L G+ P ++TS SN++ + + SD+ +++GF+ +
Sbjct: 678 VEVRSGLSPDAKLHGRFCGS-ETPEVITSQSNNMRVEFKSDNTVSKRGFRAHF 729
Score = 91.3 bits (225), Expect = 2e-17
Identities = 80/303 (26%), Positives = 125/303 (41%), Gaps = 77/303 (25%)
Query: 17 HHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEED 76
H + AG C ++ GT+ SP +P YP+ CTW I++ HR++L F F +E+
Sbjct: 769 HDCKEAG--CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQH 826
Query: 77 ----FDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYE 132
+D L ++DGP + R G + P V++ +++ LR SD +V +GF A +
Sbjct: 827 QECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVH- 885
Query: 133 VLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFP 192
S CG GRL +Q ++ HA G N
Sbjct: 886 ---STECG--GRLKAEVQTKELYS-----------------HA----QFGDNN------- 912
Query: 193 LPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLED- 251
+PSE A C W I+AE G + L F F++E+
Sbjct: 913 -------------------------YPSE----ARCDWVIVAEDGYGVELTFRTFEVEEE 943
Query: 252 ---GYDFLEVTGTEGSSL----WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQ 304
GYD++E SS F G+ + S+ + L + F +D ++GF A+Y
Sbjct: 944 ADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYT 1003
Query: 305 VKK 307
K
Sbjct: 1004 STK 1006
Score = 73.6 bits (179), Expect = 3e-12
Identities = 44/129 (34%), Positives = 66/129 (51%), Gaps = 5/129 (3%)
Query: 734 LKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKIT 793
L +G + + +C A CG L +G +PG+P Y C W I PG I +
Sbjct: 334 LSQGDIAQARKLYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLN 392
Query: 794 F---DRFKTEVN-YDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHS 849
F D FK+ + YD +EVRDG APL+G + G ++P+ L+ST + L++ F + +
Sbjct: 393 FTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNIL 452
Query: 850 DIGFQLRYE 858
GF YE
Sbjct: 453 GKGFFAAYE 461
Score = 70.5 bits (171), Expect = 3e-11
Identities = 35/111 (31%), Positives = 58/111 (52%), Gaps = 4/111 (3%)
Query: 1968 CGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIE 2023
CG T+++ G +PGFP YPS C W+I++ G + F + + +DY+E
Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
Query: 2024 IRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ 2074
+R+G + + ++GRF G ++P L+ST V F S + GF Y+
Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE 461
Score = 68.6 bits (166), Expect = 1e-10
Identities = 34/91 (37%), Positives = 48/91 (52%), Gaps = 4/91 (4%)
Query: 1465 YPPGKECDWKVTVSPDYVIALVFNIFNLEP----GYDFLHIYDGRDSLSPLIGSFYGSQL 1520
YP CDW + Y + L F F +E GYD++ YDG DS +P +G F GS
Sbjct: 913 YPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGP 972
Query: 1521 PGRIESSSNSLFLAFRSDASVSNAGFVIDYT 1551
I S+ +SL + FR+D +++ GF YT
Sbjct: 973 LEEIYSAGDSLMIRFRTDDTINKKGFHARYT 1003
Score = 67.8 bits (164), Expect = 2e-10
Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 4/110 (3%)
Query: 1445 CGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPG----YDFLH 1500
CG L +G +P +P YP C W+++V+P I L F +L YD++
Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
Query: 1501 IYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDY 1550
+ DG +PL+G F G ++P + S+ + L++ FRS +++ GF Y
Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAY 460
Score = 64.7 bits (156), Expect = 2e-09
Identities = 38/111 (34%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Query: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVS---FVTEQNW-DSLE 1851
CG L + G +PGFP Y + +CVW+I V G I + S F + W D +E
Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
Query: 1852 VFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYK 1902
V DG +LG F G +P L ST ++L++ F S ++ GF Y+
Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE 461
Score = 63.2 bits (152), Expect = 4e-09
Identities = 39/119 (32%), Positives = 56/119 (47%), Gaps = 8/119 (6%)
Query: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEED----FDVLS 81
C L G +PGFP GYP+Y++C W I+ +I L F S L + +D +
Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
Query: 82 VFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCG 140
V DG + L R G ++P +VS + L + S + +GF A YE TCG
Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA----TCG 465
Score = 62.0 bits (149), Expect = 1e-08
Identities = 35/130 (26%), Positives = 65/130 (50%), Gaps = 5/130 (3%)
Query: 554 VGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPE 613
+GQ+ Q + + K C +C +G +P +P Y ++ HCVW I P
Sbjct: 328 IGQRVRLSQGDIAQARKLYKCP-ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPG 386
Query: 614 SRIHLAFNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQ 669
+I L F +D+ +D++ ++DG +AP+LG F G+++P + S+ +EF+
Sbjct: 387 EKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFR 446
Query: 670 TDHSTGKRGF 679
+ + +GF
Sbjct: 447 SSSNILGKGF 456
Score = 58.5 bits (140), Expect = 1e-07
Identities = 39/130 (30%), Positives = 66/130 (50%), Gaps = 11/130 (8%)
Query: 397 RPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERG 456
R + + C L+ +G ++P FP Y + +HCVW I ++ P + I L F DL +
Sbjct: 343 RKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRI-SVTPGEKIVLNFTSMDLFKS 401
Query: 457 ----YDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKAS 512
YD + V DG + +L G +P+ +VST+ ++W+ F++ + GF A+
Sbjct: 402 RLCWYDYVEVRDG--YWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAA 459
Query: 513 YEEIEQGSCG 522
YE +CG
Sbjct: 460 YE----ATCG 465
Score = 58.5 bits (140), Expect = 1e-07
Identities = 57/212 (26%), Positives = 82/212 (38%), Gaps = 32/212 (15%)
Query: 673 STGKRGFNITFTTF---RHNEC----------PDPGVPVNGKRFGDSLQLGSSISFLCDE 719
ST +TF F +H EC PD P+ G RF S + +++
Sbjct: 808 STAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILG-RFCGSKKPDPTVA----- 861
Query: 720 GFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGF----YKDA 775
GS + SV CGG L + T F Y
Sbjct: 862 -----SGSSMFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSE 916
Query: 776 LSCAWVIEAQPGYPIKITFDRFKTE----VNYDTLEVRDGRTYSAPLIGVYHGTQVPQFL 831
C WVI A+ GY +++TF F+ E YD +E DG SAP +G + G+ + +
Sbjct: 917 ARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEI 976
Query: 832 ISTSNYLYLLFSTDKSHSDIGFQLRYETITLQ 863
S + L + F TD + + GF RY + Q
Sbjct: 977 YSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008
Score = 57.0 bits (136), Expect = 3e-07
Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 10/122 (8%)
Query: 1091 LPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEG-- 1148
L +C A CG ++ T G +P FP Y + C++ I PG+ I L + +L +
Sbjct: 345 LYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL 403
Query: 1149 ---DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSS 1205
D ++V DG A LLG F + + L ST S LW++F + + KGF F++
Sbjct: 404 CWYDYVEVRDGYWRKAPLLGRFC-GDKIPEPLVSTDSRLWVEFRSSSNILGKGF---FAA 459
Query: 1206 FE 1207
+E
Sbjct: 460 YE 461
Score = 52.4 bits (124), Expect = 8e-06
Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 5/102 (4%)
Query: 2175 LPKCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSG- 2233
L KC CG + + G +PGFP+ Y S CVW I+V G + LN + + S
Sbjct: 345 LYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL 403
Query: 2234 ---DFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKF 2272
D++ + DG + AP LG F + + S+ +++ ++F
Sbjct: 404 CWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEF 445
Score = 49.3 bits (116), Expect = 7e-05
Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 2355 CPT-NELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISL---TVEYFLSEK-QYD 2409
CP E L D+TG + +P YP + C W + V P I L +++ F S YD
Sbjct: 348 CPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYD 407
Query: 2410 EFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465
E+ DG ++PLL G+ P + S+ + +++ + S KGF Y A
Sbjct: 408 YVEVRDGYWRKAPLLGRFCGD-KIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA 462
Score = 47.4 bits (111), Expect = 3e-04
Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 6/94 (6%)
Query: 914 SRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLES 973
+R L C A CG +Q ++G +PGFP+ YP+ +C W I + G+ + F + L
Sbjct: 342 ARKLYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFK 400
Query: 974 G----HDYLLITENGSFTQP-LRQLTGSRLPAPI 1002
+DY+ + + P L + G ++P P+
Sbjct: 401 SRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPL 434
Score = 46.2 bits (108), Expect = 6e-04
Identities = 34/129 (26%), Positives = 57/129 (44%), Gaps = 6/129 (4%)
Query: 1262 RPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE 1321
R L C A CG T++ + +G +PG+P Y +C+W I G I L+F D +
Sbjct: 343 RKLYKCPA-CGETLQ-DTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFK 400
Query: 1322 V----HDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQF 1377
+D + + DG LL G +P+ L ST + + ++F + +GF +
Sbjct: 401 SRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAY 460
Query: 1378 SVSTATSCN 1386
+ N
Sbjct: 461 EATCGGDMN 469
Score = 42.0 bits (97), Expect = 0.011
Identities = 31/113 (27%), Positives = 54/113 (47%), Gaps = 6/113 (5%)
Query: 1619 CGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTV-PKDYVV--FGQFAFFHTAL--NDVVE 1673
CG + G +P +P Y S C++ ++V P + +V F F + L D VE
Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
Query: 1674 VHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQA 1726
V DG+ + + LL G E L ++T +++ ++F + +GF Y+A
Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPL-VSTDSRLWVEFRSSSNILGKGFFAAYEA 462
>gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 [Homo
sapiens]
Length = 809
Score = 193 bits (490), Expect = 3e-48
Identities = 127/403 (31%), Positives = 196/403 (48%), Gaps = 15/403 (3%)
Query: 1208 LIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTC 1267
L+ C P P G + H G + +F CD GY L+G E L+CL+G R +W+ P+C
Sbjct: 173 LLSCGFPPRPAHGDVSVTDLH-PGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 231
Query: 1268 VAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLR 1327
+A CGGT+ G+++SP NL C W IEA G + LHF +E +D L
Sbjct: 232 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 291
Query: 1328 IWDGPVESGVLLKELSGPALP-KDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCN 1386
+ G ++ + +P + L S S+ ++ ++ + +++F C
Sbjct: 292 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 351
Query: 1387 DPGIPQ-NGSRSGDSWEAGDSTVFQCDPGYALQGSA---EISCVKIENRFFWQPSPPTCI 1442
P + N + + + G F C PGYAL+ I CV W + P C
Sbjct: 352 APFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVD-PTEPHWNDTEPACK 410
Query: 1443 APCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIY 1502
A CGG+L+ P+GV+LSP++P+ Y PG++C W V V + I L I N+ G D L ++
Sbjct: 411 AMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLF 469
Query: 1503 DGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSN----AGFVIDYTENPR-ES 1557
DG + ++ G Q R+ SS L L F++ N GFV+ + E PR ++
Sbjct: 470 DGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT 529
Query: 1558 CFDPGSIKNGTRVGS--DLKLGSSVTYYCHGGYEVEGTSTLSC 1598
C + + G R S DL G+ +TY C GYE+ G+ L+C
Sbjct: 530 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC 572
Score = 189 bits (479), Expect = 5e-47
Identities = 164/636 (25%), Positives = 259/636 (40%), Gaps = 73/636 (11%)
Query: 1384 SCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIA 1443
SC P P +G S G + F CD GY LQG + C+ R W P+C+A
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN-GTRPSWNGETPSCMA 233
Query: 1444 PCGGDLTGPS-GVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIY 1502
CGG + + G I+SP P C W + + + L F +L+ D L +
Sbjct: 234 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 293
Query: 1503 DGRDSLSPLIGSFYGSQLPGR-IESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDP 1561
G LSP+I +P R + S + SL++ S+ + + + + CF P
Sbjct: 294 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 353
Query: 1562 GSIK-NGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDG-KPVWNNPRPVCTAPC 1619
N T + + G+ T+ C GY +E + I D +P WN+ P C A C
Sbjct: 354 FLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMC 413
Query: 1620 GGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHS 1679
GG+ GVVLSP++PQ+Y+ GQ C++ V V ++ + Q + D++ + DG
Sbjct: 414 GGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDG 473
Query: 1680 QHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAP----ARGFHFVYQAVPRTSATQC 1735
+R+L+ L G L L++ + ++F A P +GF ++ VPR C
Sbjct: 474 PSARVLAQLRGPQPRRRL-LSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT--C 530
Query: 1736 SSVPEPRYGKRLGS--DFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC- 1792
+P P +G R S D G ++ ++C GY L GS + C W+ + P C
Sbjct: 531 PELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPACQ 586
Query: 1793 -VVPCG--GNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDS 1849
++ C G + T GF P G+ +Q + + +
Sbjct: 587 KIMTCADPGEIANGHRTASDAGF----------------PVGSHVQYRCLPGYS------ 624
Query: 1850 LEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSC 1909
+GA A+L S +SD A L+Y+ C
Sbjct: 625 ---LEGA----------------AMLTCYSRDTGTPKWSDRVPKCA---LKYE-----PC 657
Query: 1910 PEPAVPSNGVKT--GERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQ 1967
P VP NG +T Y + + F C G+ L G I+C+PG +W PPLC
Sbjct: 658 LNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVA 717
Query: 1968 CGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVG 2003
++ + + P + + I LP+G
Sbjct: 718 YEELLDNRKLEVTQTTDPSRQLEGGNLALAILLPLG 753
Score = 180 bits (456), Expect = 3e-44
Identities = 153/591 (25%), Positives = 245/591 (41%), Gaps = 68/591 (11%)
Query: 867 CLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQ--WSRALPSCEALC 924
C P P +G D + G TF CDSGY L E L C + W+ PSC A C
Sbjct: 176 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASC 235
Query: 925 GGFIQGSS-GTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITEN 983
GG I ++ G I+SP NL C W+IE + G+ + F L+ +D L++
Sbjct: 236 GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSG 295
Query: 984 GSFTQPLRQLTGSRLPAPISAGLYGNFTA-QVRFISDFSMSYEGFNITFSEYDLEPCEEP 1042
GS P+ + S + GL + + V +S+ + ++ F ++ + C P
Sbjct: 296 GSPLSPV--IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 353
Query: 1043 EVPAYSIRK-GLQFGVGDTLTFSCFPGYRLEGTA---RITCLGGRRRLWSSPLPRCVAEC 1098
+ ++ ++ G TFSC PGY LE I C+ W+ P C A C
Sbjct: 354 FLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMC 413
Query: 1099 GNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNN 1158
G ++ G +LSP++P +Y+ +C++ + Q K I L+ + EGD+L ++DG+
Sbjct: 414 GGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDG 473
Query: 1159 NSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDA----ENTSKGFELHFSSF-ELIKCED 1213
SAR+L + L S+ L L F +GF LHF C +
Sbjct: 474 PSARVLAQLRGPQPRR-RLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPE 532
Query: 1214 PGTPKFGYKVHDEGH-FAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECG 1272
P++G++ G G+ +++ C+PGY L GS+ L C WD C
Sbjct: 533 LPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC------QWDLSWSAAPPACQ 586
Query: 1273 GTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGP 1332
+ G++ + A ++AG +G H
Sbjct: 587 KIMTCADPGEIANGHRTA-------------SDAGFPVGSH------------------- 614
Query: 1333 VESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQ 1392
V + L G +L +++ +S D T K + C +PG+P+
Sbjct: 615 ----VQYRCLPGYSLEG------AAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPE 664
Query: 1393 NGSRS--GDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC 1441
NG ++ ++AG+S F C G+ L G I+CV + W PP C
Sbjct: 665 NGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVP-GHPSQWTSQPPLC 714
Score = 167 bits (423), Expect = 2e-40
Identities = 156/648 (24%), Positives = 253/648 (39%), Gaps = 96/648 (14%)
Query: 465 GGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDP 524
G + G+++T I+T T+V + S + + SCG P
Sbjct: 145 GPEGGEEETTTTIITTTTVTTTVTSPAYLL-------------------------SCGFP 179
Query: 525 GIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQ--WSAKKPGCVFSCFFNF 582
PA+G + H G T F C ++L G++ + C + W+ + P C+ SC
Sbjct: 180 PRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGGTI 239
Query: 583 TSPS-GVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAE 641
+ + G ++SP G +L C W+I A R+HL F + ++ D L+++ G +
Sbjct: 240 HNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPL 299
Query: 642 APVLGTFSGNQLPS-SITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNG 700
+PV+ + +P + S +E ++ ++ F F + C P +
Sbjct: 300 SPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGN 359
Query: 701 KRFGD-SLQLGSSISFLCDEGF-LGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTS 758
D + G+ +F C G+ L G + WN C+A CGG L+
Sbjct: 360 VTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSE 419
Query: 759 PSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPL 818
P+G +LSP WP Y C W + Q I + + D L + DG SA +
Sbjct: 420 PAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGPSARV 478
Query: 819 IGVYHGTQVPQFLISTSNYLYLLFSTDKSHSD----IGFQLRYETITLQSDHCLDPGIPV 874
+ G Q + L+S+ L L F + GF L ++ + ++D C + P
Sbjct: 479 LAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVP-RNDTCPELPPPE 537
Query: 875 NGQR---HGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGGFIQGS 931
G R HG D G ++T+ C+ GY L + L C+ + WS A P+C+ +
Sbjct: 538 WGWRTASHG-DLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIM------- 589
Query: 932 SGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLR 991
T PG E ++G H ++G GS Q R
Sbjct: 590 --TCADPG---------------EIANG-------HRTASDAGFPV------GSHVQ-YR 618
Query: 992 QLTGSRLPAPISAGLYGNFTAQVRF---ISDFSMSYEGFNITFSEYDLEPCEEPEVP--A 1046
L G L Y T ++ + ++ YE PC P VP
Sbjct: 619 CLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYE------------PCLNPGVPENG 666
Query: 1047 YSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRC 1094
Y + G++L F C+ G+ L G ITC+ G W+S P C
Sbjct: 667 YQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 714
Score = 162 bits (411), Expect = 4e-39
Identities = 140/511 (27%), Positives = 205/511 (40%), Gaps = 74/511 (14%)
Query: 1735 CSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVV 1794
C P P +G +D G F C+SGY LQG + CL G WN P+C+
Sbjct: 176 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN--GTRPSWNGETPSCMA 233
Query: 1795 PCGGNLTERR-GTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVF 1853
CGG + G I+SP +L C W I EG + + +++ D L V
Sbjct: 234 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 293
Query: 1854 DGADNTVTMLGSFSGTTVPAL-LNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEP 1912
G ++ VP L S + LY+ S+ + L ++ C P
Sbjct: 294 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 353
Query: 1913 AVPSNGVKTGE-RYLVNDVVSFQCEPGYALQGHAH---ISCMPGTVRRWNYPPPLCIAQC 1968
+ V T + Y + +F C PGYAL+ I C+ T WN P C A C
Sbjct: 354 FLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMC 413
Query: 1969 GGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQ-------FLNFSTEPNHDY 2021
GG + E GV+LSP +P +Y DC W G H+Q + D
Sbjct: 414 GGELSEPAGVVLSPDWPQSYSPGQDCVW--------GVHVQEEKRILLQVEILNVREGDM 465
Query: 2022 IEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRP----GFKLEYQDL- 2076
+ + +G ++R++ + G + LLS+ + T+ F + P GF L ++++
Sbjct: 466 LTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVP 525
Query: 2077 ----------------TYSHQISSFLRGFDLS-------ELERTNSTPPVAASYVWDLD- 2112
T SH +RG L+ EL ++ + WDL
Sbjct: 526 RNDTCPELPPPEWGWRTASH--GDLIRGTVLTYQCEPGYELLGSD-----ILTCQWDLSW 578
Query: 2113 ----PGCEAYELQECPDPEPFANG--IVRGAGYNVGQSVTFECLPGYQLTGHPVLTC--- 2163
P C+ ++ C DP ANG AG+ VG V + CLPGY L G +LTC
Sbjct: 579 SAAPPACQ--KIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSR 636
Query: 2164 QHGTNRNWDHPLPKCEV---PCGGNITSSNG 2191
GT + W +PKC + PC NG
Sbjct: 637 DTGTPK-WSDRVPKCALKYEPCLNPGVPENG 666
Score = 162 bits (410), Expect = 5e-39
Identities = 158/641 (24%), Positives = 243/641 (37%), Gaps = 117/641 (18%)
Query: 1906 LSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCI 1965
L SC P P++G + +F C+ GY LQG + C+ GT WN P C+
Sbjct: 173 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 232
Query: 1966 AQCGGTVEEME-GVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEI 2024
A CGGT+ G I+SP G N+ C W I G H+ F S + ++D + +
Sbjct: 233 ASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMV 292
Query: 2025 RNGPYETSRMMGRFSGSELPS-SLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQIS 2083
R+G S ++ ++P L+S + V S+ N L ++ +
Sbjct: 293 RSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFA 352
Query: 2084 SFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQ 2143
FL A+ DPE Y G
Sbjct: 353 PFL------------------------------AHGNVTTTDPE-----------YRPGA 371
Query: 2144 SVTFECLPGYQLT--GHP-VLTCQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPS 2200
TF CLPGY L G P + C T +W+ P C+ CGG ++ G V SP +P
Sbjct: 372 LATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQ 431
Query: 2201 PYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKT 2260
YS QDCVW + V + L + +L GD +T++DG +A L ++
Sbjct: 432 SYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDGPSARVLAQLRGPQPRRR 490
Query: 2261 VQSSSNQVLLKFHR-----DAATGGIFAIAFSAYPLT-KCPPPTILPNAE---VVTENEE 2311
+ SS + L+F + G F + F P CP LP E + +
Sbjct: 491 LLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPE---LPPPEWGWRTASHGD 547
Query: 2312 FNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICE--VHCPTNELLTDSTGVIL 2369
G ++ Y+C PG+ L+G++ILTC+ L + PP C+ + C + +
Sbjct: 548 LIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPPACQKIMTCADPGEIANGHRTAS 605
Query: 2370 SQSYP-GSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALS 2428
+P GS+ Q+ R P Y++
Sbjct: 606 DAGFPVGSHVQY-------RCLPGYSLE-------------------------------- 626
Query: 2429 GNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAPLHGF-ILGQTSTQP 2487
A ++ S ++ +WS + K C P P +G+ L + Q
Sbjct: 627 ---GAAMLTCYSRDTGTPKWSD------RVPKCALKYEPCLNPGVPENGYQTLYKHHYQA 677
Query: 2488 GGSIHFGCNAGYRLVGHSMAICT-RHPQGYHLWSEAIPLCQ 2527
G S+ F C G+ L+G C HP W+ PLC+
Sbjct: 678 GESLRFFCYEGFELIGEVTITCVPGHPS---QWTSQPPLCK 715
Score = 157 bits (398), Expect = 1e-37
Identities = 139/558 (24%), Positives = 225/558 (40%), Gaps = 36/558 (6%)
Query: 2120 LQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCE 2179
L C P A+G V + G + TF C GYQL G L C +GT +W+ P C
Sbjct: 173 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 232
Query: 2180 VPCGGNITSSN-GTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITI 2238
CGG I ++ G + SP + C W+I G + L+ + + D + +
Sbjct: 233 ASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMV 292
Query: 2239 WDGPQQTAPRLGVFTRSM----AKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKC 2294
G +P ++ M + + + + + A + ++ F A+ +C
Sbjct: 293 RSGGSPLSP--VIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRC 350
Query: 2295 PPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLV---GNEILTCKLGTYLQFEGPPPIC 2351
P L + V T + E+ G + + CLPG+ L + C T + P C
Sbjct: 351 FAP-FLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPAC 409
Query: 2352 EVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEF 2411
+ C L++ GV+LS +P SY Q C W V V+ + I L VE L+ ++ D
Sbjct: 410 KAMCGGE--LSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVE-ILNVREGDML 466
Query: 2412 EIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLP 2471
+FDG + +L L G ++ SS + L++ + G + + +P
Sbjct: 467 TLFDGDGPSARVLAQLRGPQPRRRLL-SSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVP 525
Query: 2472 R--------APLHGFILGQTSTQPGGSI-HFGCNAGYRLVGHSMAICTRHPQGYHLWSEA 2522
R P G+ G++ + C GY L+G + C Q WS A
Sbjct: 526 RNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAA 581
Query: 2523 IPLCQ-ALSCGLPEAPKNGMVFGKE--YTVGTKAMYSCSEGYHLQAGAEATAECLDTGL- 2578
P CQ ++C P NG + + VG+ Y C GY L+ A T DTG
Sbjct: 582 PPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTP 641
Query: 2579 -WSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIR 2637
WS+R P+C P ++ E+G ++ +++ YQ L C G+ G+ I
Sbjct: 642 KWSDR--VPKCALKYEPCLNPGVPENG-YQTLYKHHYQAGESLRFFCYEGFELIGEVTIT 698
Query: 2638 CQANGKWSLGDSTPTCRI 2655
C P C++
Sbjct: 699 CVPGHPSQWTSQPPLCKV 716
Score = 137 bits (346), Expect = 1e-31
Identities = 166/709 (23%), Positives = 262/709 (36%), Gaps = 105/709 (14%)
Query: 328 TSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVS 387
T+V T V C P P G +D G + F C+ GY LQG + + C+ +
Sbjct: 161 TTVTTTVTSPAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL--N 218
Query: 388 DMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLA 447
+W+ P C A G I SP N C W+I A + + L
Sbjct: 219 GTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAE-GRRLHLH 277
Query: 448 FEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDL-IVSTNHQMWLLFQTDGSGSS 506
FE L+ D L V GG V+Y VP+ ++S +++ ++ +
Sbjct: 278 FERVSLDEDNDRLMVRSGG--SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANP 335
Query: 507 LGFKASYEEIEQGSCGDPGIPAYGR--REGSRFHHGDTLKFECQPAFELV---GQKAITC 561
L +E E+ C P + A+G + G F C P + L AI C
Sbjct: 336 LLLSLRFEAFEEDRCFAPFL-AHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIEC 394
Query: 562 QKNNQ--WSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLA 619
+ W+ +P C C + P+GVVLSP++P+ Y CVW + + E RI L
Sbjct: 395 VDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQ 454
Query: 620 FNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGF 679
++V + D L + DG A VL G Q + SSG L+FQ G
Sbjct: 455 VEILNVR-EGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGL 513
Query: 680 NITFTTF-----RHNECPDPGVPVNGKR---FGDSLQLGSSISFLCDEGFLGTQGSETIT 731
F R++ CP+ P G R GD ++ G+ +++ C+ G+ GS+ +T
Sbjct: 514 GQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIR-GTVLTYQCEPGY-ELLGSDILT 571
Query: 732 CVLKEGSVVWNSA------VLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQ 785
C + + W++A ++ C P G + + T G+P C
Sbjct: 572 C---QWDLSWSAAPPACQKIMTCADP--GEIANGHRTASDAGFPVGSHVQYRCL------ 620
Query: 786 PGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVY-HGTQVPQFLISTSNYLYLLFST 844
PGY ++ A ++ Y T P++
Sbjct: 621 PGYSLE-----------------------GAAMLTCYSRDTGTPKW-------------- 643
Query: 845 DKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQR--HGNDFYVGALVTFSCDSGYTLSDG 902
SD R L+ + CL+PG+P NG + + + + G + F C G+ L
Sbjct: 644 ----SD-----RVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGE 694
Query: 903 EPLECEPNF--QWSRALPSCEALCGGFIQGSSGTILSPGFP--DFYPNNLNCTWIIETS- 957
+ C P QW+ P C+ + + P NL ++
Sbjct: 695 VTITCVPGHPSQWTSQPPLCKVAYEELLDNRKLEVTQTTDPSRQLEGGNLALAILLPLGL 754
Query: 958 ---HGKGVFFTF------HTFHLESGHDYLLITENGSFTQPLRQLTGSR 997
G GV+ + F H Y IT F+ PL + +R
Sbjct: 755 VIVLGSGVYIYYTKLQGKSLFGFSGSHSYSPITVESDFSNPLYEAGDTR 803
Score = 132 bits (331), Expect = 8e-30
Identities = 128/455 (28%), Positives = 196/455 (43%), Gaps = 62/455 (13%)
Query: 138 TCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCR 197
+CG P R +G + + G + C+ G+ L+G L C G+ S W+ PSC
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPS--WNGETPSCM 232
Query: 198 ADDACGGTLRGQS-GIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFL 256
A +CGGT+ + G I SP N C W I A G + L F L++ D L
Sbjct: 233 A--SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRL 290
Query: 257 EVTGTEGSSLWFTGASLPAPVISSKNWLRLHFTSD-GNHRQRGFSAQYQVKKQIELKSR- 314
V +G S +PVI + SD + +RG + Q +EL S
Sbjct: 291 MVR---------SGGSPLSPVI---------YDSDMDDVPERGLISDAQ-SLYVELLSET 331
Query: 315 --GVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEG 372
L+ + + + ++ G+ DP ++R G+ F+C G
Sbjct: 332 PANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDP-----------EYRPGALATFSCLPG 380
Query: 373 YDLQ---GSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNA 429
Y L+ I C+ ++ W+D P C+A MC L P+G++ SP++P Y
Sbjct: 381 YALEPPGPPNAIECVDPTE--PHWNDTEPACKA-MCGGELSEPAGVVLSPDWPQSYSPGQ 437
Query: 430 HCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVS 489
CVW + + K I L E ++ G D LT+ DG DG VL L G ++S
Sbjct: 438 DCVWGV-HVQEEKRILLQVEILNVREG-DMLTLFDG--DGPSARVLAQLRGPQPRRRLLS 493
Query: 490 TNHQMWLLFQT----DGSGSSLGFKASYEEIEQG-SCGDPGIPAYGRREGSRFHHGD--- 541
+ + L FQ G GF ++E+ + +C + P +G R S HGD
Sbjct: 494 SGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTAS---HGDLIR 550
Query: 542 --TLKFECQPAFELVGQKAITCQKNNQWSAKKPGC 574
L ++C+P +EL+G +TCQ + WSA P C
Sbjct: 551 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 585
Score = 118 bits (295), Expect = 1e-25
Identities = 151/581 (25%), Positives = 212/581 (36%), Gaps = 79/581 (13%)
Query: 2650 TPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGL---WSG 2706
T ++SCG P P +G T G TA F C+SGY L G C+ NG W+G
Sbjct: 168 TSPAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNG 226
Query: 2707 SEVRCLAGHCGT-----------PEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRI 2755
C+A GT PEP G G N + R V + G RL R+
Sbjct: 227 ETPSCMASCGGTIHNATLGRIVSPEP---GGAVGPNLTCRW--VIEAAEGRRLHLHFERV 281
Query: 2756 CQQDHH-----WSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNS 2810
+ + SG +P ++ P + D+ ++ + L+
Sbjct: 282 SLDEDNDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLR 341
Query: 2811 TRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLR-- 2868
D + L H + T+ DP + PG + FSC G+ L
Sbjct: 342 FEAFEEDRCFAPFLAHGNVTTT----DP-----------EYRPGALATFSCLPGYALEPP 386
Query: 2869 ---GSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYY 2925
+ E W+ ++P C + G P A VV S S S +C G +
Sbjct: 387 GPPNAIECVDPTEPHWNDTEPACKAMCGGELSEP--AGVVLSPDWPQSYSPGQDCVWGVH 444
Query: 2926 ATG----------LLSRHCSVNGTWTGSDPECLVI-NCGDPGIPANGLRLGNDFRYNKTV 2974
L R + + G P V+ P L G D T+
Sbjct: 445 VQEEKRILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDL----TL 500
Query: 2975 TYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSSV 3034
+Q PG + K+ N T P PPP D + G+ +
Sbjct: 501 QFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPEL------PPPEWGWRTASHGDLIRGTVL 554
Query: 3035 TYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVF-CGDPGVPSRGRR--EDRGFSYRSS 3091
TY C GY+L + TC+ + SW+ P C + C DPG + G R D GF S
Sbjct: 555 TYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSH 614
Query: 3092 VSFSCHPPLVLVGSPRRFCQSDGT----WSGTQPSCIDPTLTTCADPGVPQFGIQN-NSQ 3146
V + C P L G+ C S T WS P C C +PGVP+ G Q
Sbjct: 615 VQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCA-LKYEPCLNPGVPENGYQTLYKH 673
Query: 3147 GYQVGSTVLFRCQKGYLLQGSTTRTCLPN--LTWSGTPPDC 3185
YQ G ++ F C +G+ L G T TC+P W+ PP C
Sbjct: 674 HYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 714
Score = 102 bits (253), Expect = 9e-21
Identities = 139/573 (24%), Positives = 200/573 (34%), Gaps = 129/573 (22%)
Query: 2771 LVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMC--GLDGHWTGSLPHCS 2828
L+SCG P P H +S G + C L G T +C G W G P C
Sbjct: 173 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 232
Query: 2829 GTSVGVCGDPGIPAHGIRLGD--SFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQP 2886
+ G H LG S +PG + + V+ + R +
Sbjct: 233 ASCGGTI-------HNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDE 285
Query: 2887 ECGVISCGNPGTPSNARVVFSD-------GLVFSSSIVYECREGYYATGLLSRHCSVNGT 2939
+ + + G+P + + SD GL+ + +Y LLS
Sbjct: 286 DNDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLY--------VELLSE------- 330
Query: 2940 WTGSDPECLVIN--------CGDPGIP-ANGLRLGNDFRYNKTVTYQCVPGYMMESHRV- 2989
T ++P L + C P + N ++R T+ C+PGY +E
Sbjct: 331 -TPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPP 389
Query: 2990 SVLSCTK--DRTWNGTKPVCKAL----MCKPPPLI-----PNGKVVGSDFMWGSSVTYA- 3037
+ + C + WN T+P CKA+ + +P ++ P G D +WG V
Sbjct: 390 NAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEK 449
Query: 3038 ----------CLEGYQLSLPAVFTCEGNGSWTGEL----------------PQCFPVFCG 3071
EG L+L +G+G L P F
Sbjct: 450 RILLQVEILNVREGDMLTL-----FDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQA 504
Query: 3072 DPGVPSRG----------------------------RREDRGFSYRSSV-SFSCHPPLVL 3102
PG P+ G R G R +V ++ C P L
Sbjct: 505 PPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYEL 564
Query: 3103 VGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQ-GYQVGSTVLFRCQKG 3161
+GS CQ D +WS P+C + TCADPG G + S G+ VGS V +RC G
Sbjct: 565 LGSDILTCQWDLSWSAAPPAC--QKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPG 622
Query: 3162 YLLQGSTTRTCLPNLT----WSGTPPDCVPHH--CRQPETPTHANVGALDLP-SMGYTLI 3214
Y L+G+ TC T WS P C + C P P + G +L
Sbjct: 623 YSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLR 682
Query: 3215 YSCQEGFSLKGGSEHRTCKAD--GSWTGKPPIC 3245
+ C EGF L G TC WT +PP+C
Sbjct: 683 FFCYEGFELIG-EVTITCVPGHPSQWTSQPPLC 714
Score = 82.8 bits (203), Expect = 5e-15
Identities = 105/408 (25%), Positives = 155/408 (37%), Gaps = 56/408 (13%)
Query: 40 PGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG--PPQPENLRTRLT 97
PG G PN C W I A E R+ L F+ +L+ED D L V G P P + +
Sbjct: 252 PGGAVG-PNLT-CRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPVIYDSDMD 309
Query: 98 GFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRLPNGIQQGST-FN 156
++S A +L + L+S+ + +E C P + +
Sbjct: 310 DVP-ERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYR 368
Query: 157 LGDKVRYSCNLGFFLEGHA---VLTCHAGSENSATWDFPLPSCRADDACGGTLRGQSGII 213
G +SC G+ LE + C +E W+ P+C+A CGG L +G++
Sbjct: 369 PGALATFSCLPGYALEPPGPPNAIECVDPTEPH--WNDTEPACKA--MCGGELSEPAGVV 424
Query: 214 SSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSSLWFTGASL 273
SP +P Y DC W + + I L + +G D L + +G S A L
Sbjct: 425 LSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGPSARVL-AQL 482
Query: 274 PAP-----VISSKNWLRLHFTSDGNHRQRGFSAQYQVK-KQIELKSRGVKLMP------- 320
P ++SS L L F + G + + K++ +L P
Sbjct: 483 RGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRT 542
Query: 321 -SKDNSQKTSVLT-----------------QVGVS--------QGHNMCPDPGIPERGKR 354
S + + +VLT Q +S Q C DPG G R
Sbjct: 543 ASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHR 602
Query: 355 LGSD--FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVC 400
SD F +GS VQ+ C GY L+G+ +TC WSD P C
Sbjct: 603 TASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKC 650
Score = 75.9 bits (185), Expect = 7e-13
Identities = 47/165 (28%), Positives = 74/165 (44%), Gaps = 10/165 (6%)
Query: 2854 GTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPEC-GVISCGNPGTPSNARVVFSD-GLV 2911
GTV+ + CE G+ L GS TCQ + SWS + P C +++C +PG +N SD G
Sbjct: 551 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFP 610
Query: 2912 FSSSIVYECREGYYATGLLSRHCSVNGT----WTGSDPECLV--INCGDPGIPANGLR-- 2963
S + Y C GY G C T W+ P+C + C +PG+P NG +
Sbjct: 611 VGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTL 670
Query: 2964 LGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCK 3008
+ ++ +++ + C G+ + W P+CK
Sbjct: 671 YKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCK 715
Score = 73.2 bits (178), Expect = 4e-12
Identities = 50/168 (29%), Positives = 75/168 (44%), Gaps = 13/168 (7%)
Query: 2735 RGSVV-YQCNAGFRLIGMSVRICQQDHHWSGKTPFC-VLVSCGHPG--SPPHSQMSGDSY 2790
RG+V+ YQC G+ L+G + CQ D WS P C +++C PG + H S +
Sbjct: 550 RGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGF 609
Query: 2791 TVGAVVRYSCIGKRTLVGNSTRMCGL----DGHWTGSLPHCSGTSVGVCGDPGIPAHGIR 2846
VG+ V+Y C+ +L G + C W+ +P C+ C +PG+P +G +
Sbjct: 610 PVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCA-LKYEPCLNPGVPENGYQ 668
Query: 2847 --LGDSFDPGTVMRFSCEAGHVLRGSSERTCQAN--GSWSGSQPECGV 2890
+ G +RF C G L G TC W+ P C V
Sbjct: 669 TLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKV 716
Score = 60.8 bits (146), Expect = 2e-08
Identities = 57/215 (26%), Positives = 89/215 (41%), Gaps = 20/215 (9%)
Query: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG 85
C +L P G V SP +P Y +C W + +E+ RI L + + E D+L++FDG
Sbjct: 413 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDG 471
Query: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVS----AQGFHATYEVLP-SHTCG 140
+ +L G Q ++S+ L+L+ + QGF ++ +P + TC
Sbjct: 472 DGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTC- 530
Query: 141 NPGRLPNGIQQGSTFNLGDKVR-----YSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
LP T + GD +R Y C G+ L G +LTC + +W P+
Sbjct: 531 --PELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPA 584
Query: 196 CRADDACG--GTLRGQSGIISSPHFPSEYHNNADC 228
C+ C G + S FP H C
Sbjct: 585 CQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRC 619
Score = 44.7 bits (104), Expect = 0.002
Identities = 39/134 (29%), Positives = 54/134 (40%), Gaps = 6/134 (4%)
Query: 1738 VPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCG 1797
VPE Y + G +RF C G+ L G I C VPG +QW P C V
Sbjct: 662 VPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC--VPGHPSQWTSQPPLCKVAYE 719
Query: 1798 GNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQI--QVVSFVTEQNWDSLEVFDG 1855
L R+ + P L N I++P G I + V + T+ SL F G
Sbjct: 720 ELLDNRKLEVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSG 779
Query: 1856 AD--NTVTMLGSFS 1867
+ + +T+ FS
Sbjct: 780 SHSYSPITVESDFS 793
Score = 44.3 bits (103), Expect = 0.002
Identities = 39/175 (22%), Positives = 70/175 (40%), Gaps = 9/175 (5%)
Query: 234 AELGDTIALVFIDFQLEDGYDFL--EVTGTEGSSLWFTGASLPAPVISSKNWLRL---HF 288
A GD I + +Q E GY+ L ++ + W +++ + + H
Sbjct: 543 ASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHR 602
Query: 289 TSDGNHRQRGFSAQYQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGI 348
T+ G QY+ L+ + S+D + + C +PG+
Sbjct: 603 TASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGV 662
Query: 349 PERGKRL--GSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCR 401
PE G + ++ G S++F C EG++L G ITC V + W+ P+C+
Sbjct: 663 PENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC--VPGHPSQWTSQPPLCK 715
Score = 38.5 bits (88), Expect = 0.12
Identities = 30/90 (33%), Positives = 36/90 (40%), Gaps = 6/90 (6%)
Query: 2985 ESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQL 3044
E + + T T T P L C PP +G V +D G + T+ C GYQL
Sbjct: 150 EEETTTTIITTTTVTTTVTSPAY-LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQL 208
Query: 3045 SLPAVFTCEGNG---SWTGELPQCFPVFCG 3071
C NG SW GE P C CG
Sbjct: 209 QGEETLICL-NGTRPSWNGETPSCM-ASCG 236
Score = 38.5 bits (88), Expect = 0.12
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
Query: 2939 TWTGSDPECLVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDR 2998
T T + P L ++CG P PA+G D T T+ C GY ++ +
Sbjct: 164 TTTVTSPAYL-LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRP 222
Query: 2999 TWNGTKPVCKA 3009
+WNG P C A
Sbjct: 223 SWNGETPSCMA 233
>gi|148922949 complement component (3b/4b) receptor 1-like [Homo
sapiens]
Length = 569
Score = 182 bits (462), Expect = 5e-45
Identities = 143/492 (29%), Positives = 204/492 (41%), Gaps = 52/492 (10%)
Query: 2624 CDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNG--HRIGTLSVYGATAI 2681
C PGY +I C N W+ + C+ SC P P NG H I + + +
Sbjct: 65 CRPGYSGRPFSII-CLKNSVWT--SAKDKCKRKSCRNPPDPVNGMAHVIKDIQ-FRSQIK 120
Query: 2682 FSCNSGYTLVGSRVRECMANG---LWSGSEVRCLAGHCGTPEPIVNGH---INGENYSYR 2735
+SC GY L+GS C+ +G +W C CG P I NG I+ E + Y
Sbjct: 121 YSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHYG 180
Query: 2736 GSVVYQCNAG------FRLIGMSVRIC----QQDHHWSGKTPFCVLVSCGHPGSPPHSQM 2785
V Y CN G F L+G C Q WSG P C++ + P + + +
Sbjct: 181 SVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 240
Query: 2786 SGDS---YTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPA 2842
D+ +++ VV + C + G S C W LP CS VC P
Sbjct: 241 VSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSR----VCQPPPDVL 296
Query: 2843 HGIRLG---DSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGN-PGT 2898
H R D+F PG + +SCE G+ LRGS+ C G WS + P C V SC + G
Sbjct: 297 HAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQ 356
Query: 2899 PSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNG---TWTGSDPECLVINCGDP 2955
N V+F L + + + C EG+ G + +C + G W S P C +C P
Sbjct: 357 LPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETP 416
Query: 2956 GIPANGL-RLGNDFRYNKTVTYQCVPGYMMESH-RVSVLSCTKDRTWNGTKPVCKALMCK 3013
+P NG+ + D + Y C G+ + H + W+ P+C+ + C
Sbjct: 417 PVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPICQQIFCP 476
Query: 3014 PPPLIPNGKVVGS---DFMWGSSVTYAC----LEGYQLSLPAVFTC------EGNGSWTG 3060
PP I NG+ G+ D +G V+Y C G +L T GNG W+
Sbjct: 477 NPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSS 536
Query: 3061 ELPQC-FPVFCG 3071
P+C PV G
Sbjct: 537 PAPRCELPVGAG 548
Score = 167 bits (424), Expect = 1e-40
Identities = 132/484 (27%), Positives = 205/484 (42%), Gaps = 47/484 (9%)
Query: 2682 FSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHING-ENYSYRGSVVY 2740
+ C GY+ + C+ N +W+ ++ +C C P VNG + ++ +R + Y
Sbjct: 63 YECRPGYSGRPFSII-CLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKY 121
Query: 2741 QCNAGFRLIGMSVRICQQDHH---WSGKTPFCVLVSCGHP---GSPPHSQMSGDSYTVGA 2794
C G+RLIG S C + W KTP C + CG P + + +S + + G+
Sbjct: 122 SCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHYGS 181
Query: 2795 VVRYSC-IGKR-----TLVGNSTRMCGLD----GHWTGSLPHCSGTSVGVCGDPGIPAHG 2844
VV Y C +G R LVG + C G W+G P C C P + +G
Sbjct: 182 VVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQC--IIPNKCTPPNVE-NG 238
Query: 2845 IRLGDS---FDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSN 2901
I + D+ F V+ F C+ G ++G S CQA W P C + C P +
Sbjct: 239 ILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRV-CQPPPDVLH 297
Query: 2902 ARVVFSDGLVFS--SSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGD--PGI 2957
A D FS + Y C GY G HC+ G W+ + P C V +C D +
Sbjct: 298 AERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQL 357
Query: 2958 PANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSV-LSCTKDRTWNGTKPVCKALMCKPPP 3016
P + + + V + C G+ ++ S + + WN + PVC+ C+ PP
Sbjct: 358 PNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPP 417
Query: 3017 LIPNGKV-VGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGS---WTGELPQCFPVFCGD 3072
+ NG V V +D GS + Y+C G++L + C +G+ W+ + P C +FC +
Sbjct: 418 VPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPICQQIFCPN 477
Query: 3073 PGVPSRGRREDR---GFSYRSSVSFSCHP--------PLVLVGSPRRFCQ--SDGTWSGT 3119
P GR Y VS++C P L+ + RR + +G WS
Sbjct: 478 PPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSP 537
Query: 3120 QPSC 3123
P C
Sbjct: 538 APRC 541
Score = 156 bits (395), Expect = 3e-37
Identities = 125/424 (29%), Positives = 172/424 (40%), Gaps = 31/424 (7%)
Query: 2851 FDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGL 2910
F GT + + C G+ R S C N W+ ++ +C SC NP P N +
Sbjct: 55 FPIGTYLNYECRPGYSGRPFSI-ICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDI 113
Query: 2911 VFSSSIVYECREGYYATGLLSRHCSVNGT---WTGSDPECLVINCGDPGIPANG--LRLG 2965
F S I Y C +GY G S C ++G W P C I CG P ANG +
Sbjct: 114 QFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSIS 173
Query: 2966 ND-FRYNKTVTYQCVPGYMMES-----HRVSVLSCTKDRT---WNGTKPVCKALMCKPPP 3016
+ F Y VTY C G + S+ +KD W+G P C PP
Sbjct: 174 REYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPP 233
Query: 3017 LIPNGKVVGSD---FMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDP 3073
+ NG +V + F V + C G+ + P+ C+ W ELP C V P
Sbjct: 234 NVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRVCQPPP 293
Query: 3074 GV--PSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTC 3131
V R +R+ FS V +SC P L GS C G WS P C + +C
Sbjct: 294 DVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRC---EVKSC 350
Query: 3132 AD-PGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCL---PNLTWSGTPPDCVP 3187
D G G Q+G+ V F C +G+ L+GS+ C+ W+ + P C
Sbjct: 351 DDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCER 410
Query: 3188 HHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGS---WTGKPPI 3244
C P P + V + +G + YSC G L G S C G+ W+ KPPI
Sbjct: 411 KSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSS-AECILSGNTAHWSMKPPI 469
Query: 3245 CLEV 3248
C ++
Sbjct: 470 CQQI 473
Score = 155 bits (391), Expect = 9e-37
Identities = 135/479 (28%), Positives = 193/479 (40%), Gaps = 44/479 (9%)
Query: 2533 LPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVT 2592
LP A + E+ +GT Y C GY +G + CL +W+ + +C +
Sbjct: 41 LPFARPTNLTDDFEFPIGTYLNYECRPGY---SGRPFSIICLKNSVWT--SAKDKCKRKS 95
Query: 2593 CPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDS-TP 2651
C + +G +I QF++Q+ C GY G C +G + D+ TP
Sbjct: 96 CRNPP--DPVNGMAHVI--KDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTP 151
Query: 2652 TCRIISCGELPIPPNGHRIGTLSV---YGATAIFSCNSG------YTLVGSRVRECMAN- 2701
C I CG P NG YG+ + CN G + LVG C +
Sbjct: 152 VCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKD 211
Query: 2702 ---GLWSGSEVRCLAGHCGTPEPIVNGHINGEN---YSYRGSVVYQCNAGFRLIGMSVRI 2755
G+WSG +C+ + TP + NG + +N +S V ++C GF + G S
Sbjct: 212 DQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVK 271
Query: 2756 CQQDHHWSGKTPFCVLVSCGHPGSPPH---SQMSGDSYTVGAVVRYSCIGKRTLVGNSTR 2812
CQ + W + P C V C P H +Q D+++ G V YSC L G++
Sbjct: 272 CQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYL 330
Query: 2813 MCGLDGHWTGSLPHCSGTSVGVCGD--PGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGS 2870
C G W+ + P C V C D +P + + G + F C+ G L+GS
Sbjct: 331 HCTPQGDWSPAAPRC---EVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGS 387
Query: 2871 SERTCQANGS---WSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYAT 2927
S C G W+ S P C SC P P N V + S I Y C G+
Sbjct: 388 SASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLI 447
Query: 2928 GLLSRHCSVNGT---WTGSDPECLVINCGDPGIPANGLRLG---NDFRYNKTVTYQCVP 2980
G S C ++G W+ P C I C +P NG G D Y K V+Y C P
Sbjct: 448 GHSSAECILSGNTAHWSMKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDP 506
Score = 126 bits (317), Expect = 3e-28
Identities = 134/516 (25%), Positives = 187/516 (36%), Gaps = 68/516 (13%)
Query: 2414 FDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRA 2473
F+ P G + G P + NSV W+S K + C P
Sbjct: 53 FEFPIGTYLNYECRPGYSGRPFSIICLKNSV---WTSA--------KDKCKRKSCRNPPD 101
Query: 2474 PLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGL 2533
P++G Q I + C GYRL+G S A C +W P+C + CGL
Sbjct: 102 PVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTV-IWDNKTPVCDRIICGL 160
Query: 2534 PEAPKNG---MVFGKEYTVGTKAMYSCSEGYH----LQAGAEATAECL----DTGLWSNR 2582
P NG + + + G+ Y C+ G + E + C G+WS
Sbjct: 161 PPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWS-- 218
Query: 2583 NVPPQC-VPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQAN 2641
PQC +P C + +VE+G + + + C PG+ G ++CQA
Sbjct: 219 GPAPQCIIPNKC---TPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQAL 275
Query: 2642 GKWSLGDSTPTCRIISCGELPIPPNGHRIGTLS-----VYGATAIFSCNSGYTLVGSRVR 2696
KW P+C + P P H T G +SC GY L GS
Sbjct: 276 NKWE--PELPSCSRVC---QPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYL 330
Query: 2697 ECMANGLWSGSEVRCLAGHCGT-PEPIVNGHINGE-NYSYRGSVVYQCNAGFRLIGMSVR 2754
C G WS + RC C + NGH+ N V + C+ GF+L G S
Sbjct: 331 HCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSAS 390
Query: 2755 IC---QQDHHWSGKTPFCVLVSCGHPGSPPHSQMSG-DSYTVGAVVRYSCIGKRTLVGNS 2810
C + W+ P C SC P P + + VG+ + YSC L+G+S
Sbjct: 391 YCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHS 450
Query: 2811 TRMCGLDG---HWTGSLPHCSGTSVGVCGDP---------GIPAHGIRLGDSFD------ 2852
+ C L G HW+ P C C +P G P I G
Sbjct: 451 SAECILSGNTAHWSMKPPICQQI---FCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPH 507
Query: 2853 PGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPEC 2888
P M F+ +R +SE NG WS P C
Sbjct: 508 PDRGMTFNLIGESTIRRTSEP--HGNGVWSSPAPRC 541
Score = 82.0 bits (201), Expect = 9e-15
Identities = 128/549 (23%), Positives = 204/549 (37%), Gaps = 122/549 (22%)
Query: 2115 CEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQ-HGTNRNWDH 2173
C+ + PDP +++ + + + C GY+L G TC G WD+
Sbjct: 91 CKRKSCRNPPDPVNGMAHVIKDIQFR--SQIKYSCPKGYRLIGSSSATCIISGNTVIWDN 148
Query: 2174 PLPKCE-VPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVR-LNLSLLQTEP 2231
P C+ + CG T +NG S + S ++T G R + L EP
Sbjct: 149 KTPVCDRIICGLPPTIANGDFTSISREYFHYGS-----VVTYHCNLGSRGKKVFELVGEP 203
Query: 2232 S------GDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIA 2285
S D + IW GP AP+ +
Sbjct: 204 SIYCTSKDDQVGIWSGP---APQCII---------------------------------- 226
Query: 2286 FSAYPLTKCPPPTILPNAEVVTENEE-FNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQF 2344
KC PP + N +V++N F++ ++V +RC PGF + G + C+ ++
Sbjct: 227 -----PNKCTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQ--ALNKW 278
Query: 2345 EGPPPICEVHC--PTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYF 2402
E P C C P + L + T PG F +C EP Y++ + Y
Sbjct: 279 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQ-EVFYSC------EPGYDLRGST-YL 330
Query: 2403 LSEKQYD--------EFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAY 2454
Q D E + D GQ P +G+ PL + + ++ D +
Sbjct: 331 HCTPQGDWSPAAPRCEVKSCDDFLGQLP-----NGHVLFPLNLQLGAKVDFV---CDEGF 382
Query: 2455 NRKGFKIRY------------SAPY-----CSLPRAPLHGFILGQTSTQPGGSIHFGCNA 2497
KG Y S P C P P++G + T G I++ C
Sbjct: 383 QLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTT 442
Query: 2498 GYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGK---EYTVGTKAM 2554
G+RL+GHS A C H WS P+CQ + C P A NG G + G +
Sbjct: 443 GHRLIGHSSAECILSGNTAH-WSMKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVS 501
Query: 2555 YSCSE------GYHL--QAGAEATAECLDTGLWSNRNVPPQC-VPVTCPDVSSISVEHGR 2605
Y+C ++L ++ T+E G+WS + P+C +PV ++ V G+
Sbjct: 502 YTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWS--SPAPRCELPVGAGSHDALIV--GK 557
Query: 2606 WRLIFETQY 2614
+ +F ++
Sbjct: 558 FYEVFAEEF 566
Score = 72.4 bits (176), Expect = 7e-12
Identities = 98/437 (22%), Positives = 165/437 (37%), Gaps = 86/437 (19%)
Query: 1555 RESCFDPGSIKNG-TRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRP 1613
R+SC +P NG V D++ S + Y C GY + G+S+ +CI+ +W+N P
Sbjct: 93 RKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIIS-GNTVIWDNKTP 151
Query: 1614 VC-TAPCG--GQYVGSDGVVLSPNYPQNYTSGQICLYFVTV----PKDYVVFGQFAFFHT 1666
VC CG D +S Y + G + Y + K + + G+ + + T
Sbjct: 152 VCDRIICGLPPTIANGDFTSISREY---FHYGSVVTYHCNLGSRGKKVFELVGEPSIYCT 208
Query: 1667 ALNDVVEVHDGHSQHSRLLSSL------SGSHTGESLPLATSNQVLIKFSAKGLAPARGF 1720
+ +D V + G + + + +G ++ L + N+V+ G
Sbjct: 209 SKDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPS 268
Query: 1721 HFVYQAVPR------TSATQCSSVPEPRYGKRLGSD---FSVGAIVRFECNSGYALQGSP 1771
H QA+ + + + C P+ + +R D FS G V + C GY L+GS
Sbjct: 269 HVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGST 328
Query: 1772 EIECLPVPGALAQWNVSAPTC-VVPCGGNLTE-RRGTILSPGFPEPYLN-SLNCVWKIVV 1828
+ C P W+ +AP C V C L + G +L P LN L V
Sbjct: 329 YLHCTP----QGDWSPAAPRCEVKSCDDFLGQLPNGHVLFP------LNLQLGAKVDFVC 378
Query: 1829 PEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYS 1888
EG ++ S+ +SL +++V + S T P +N +H +
Sbjct: 379 DEGFQLKGSSASYCVLAGMESL-----WNSSVPVCERKSCETPPVPVNG-----MVHVIT 428
Query: 1889 DISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHIS 1948
DI V + +++ C G+ L GH+
Sbjct: 429 DIHVGSR-----------------------------------INYSCTTGHRLIGHSSAE 453
Query: 1949 C-MPGTVRRWNYPPPLC 1964
C + G W+ PP+C
Sbjct: 454 CILSGNTAHWSMKPPIC 470
Score = 67.4 bits (163), Expect = 2e-10
Identities = 100/457 (21%), Positives = 165/457 (36%), Gaps = 53/457 (11%)
Query: 1211 CEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCL-SGERRTWDRPLPTCVA 1269
C +P P G + S + +SC GY L GS C+ SG WD P C
Sbjct: 96 CRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDR 155
Query: 1270 ECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVH-----D 1324
G +G S Y H + T G F + ++ D
Sbjct: 156 IICGLPPTIANGDFTS--ISREYFH-YGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDD 212
Query: 1325 VLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDF-FTSKQGFAIQFSVST-- 1381
+ IW GP ++ + + P + + + N + + F + GF ++
Sbjct: 213 QVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKC 272
Query: 1382 -ATSCNDPGIP---------------QNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISC 1425
A + +P +P + R D++ G + C+PGY L+GS + C
Sbjct: 273 QALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHC 332
Query: 1426 VKIENRFFWQPSPPTCIAPCGGDLTG--PSGVILSP-NYPEPYPPGKECD----WKVTVS 1478
+ W P+ P C D G P+G +L P N CD K + +
Sbjct: 333 TPQGD---WSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSA 389
Query: 1479 PDYVIALVFNIFNLE-PGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIE-SSSNSLFLAFR 1536
V+A + +++N P + ++ ++ + RI S + L
Sbjct: 390 SYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGH 449
Query: 1537 SDASVSNAGFVIDYTENP----RESCFDPGSIKNGTRVGS---DLKLGSSVTYYCHG--- 1586
S A +G ++ P + C +P +I NG G+ D+ G V+Y C
Sbjct: 450 SSAECILSGNTAHWSMKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPD 509
Query: 1587 ---GYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCG 1620
+ + G ST+ P G VW++P P C P G
Sbjct: 510 RGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCELPVG 546
Score = 62.0 bits (149), Expect = 1e-08
Identities = 102/464 (21%), Positives = 160/464 (34%), Gaps = 97/464 (20%)
Query: 687 RHNECPDPGVPVNGKRFG-DSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAV 745
+ C +P PVNG +Q S I + C +G+ GS + TC++ +V+W++
Sbjct: 92 KRKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYR-LIGSSSATCIISGNTVIWDNKT 150
Query: 746 LRCEAP-CGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYD 804
C+ CG T +G S F+ ++ G K F+ Y
Sbjct: 151 PVCDRIICGLPPTIANGDFTSISREYFHYGSVV---TYHCNLGSRGKKVFELVGEPSIYC 207
Query: 805 TLEVRDGRTYS--APLIGVYHGTQVPQ----FLISTSNYLYLLFSTDKSHSDIGFQLRYE 858
T + +S AP + + P L+S + L+ L + GF ++
Sbjct: 208 TSKDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGP 267
Query: 859 T-ITLQSDHCLDPGIPV---------------NGQRHGNDFYVGALVTFSCDSGYTLSDG 902
+ + Q+ + +P +P QR ++F G V +SC+ GY L
Sbjct: 268 SHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGS 327
Query: 903 EPLECEPNFQWSRALPSCEA-LCGGFI-QGSSGTILSPGFPDFYPNNLNCTWIIETSHGK 960
L C P WS A P CE C F+ Q +G +L P
Sbjct: 328 TYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFP---------------------- 365
Query: 961 GVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDF 1020
+L+ G + + G QL GS + AG+ + + V
Sbjct: 366 --------LNLQLGAKVDFVCDEGF------QLKGSSASYCVLAGMESLWNSSVPVC--- 408
Query: 1021 SMSYEGFNITFSEYDLEPCEEPEVPAYS-IRKGLQFGVGDTLTFSCFPGYRLEGTARITC 1079
+ + CE P VP + VG + +SC G+RL G + C
Sbjct: 409 --------------ERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAEC 454
Query: 1080 -LGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNH 1122
L G WS P C + PN P N H
Sbjct: 455 ILSGNTAHWSMKPPIC------------QQIFCPNPPAILNGRH 486
Score = 60.8 bits (146), Expect = 2e-08
Identities = 111/479 (23%), Positives = 176/479 (36%), Gaps = 64/479 (13%)
Query: 327 KTSVLTQVGVSQGHNMCPDPGIPERGK-RLGSDFRLGSSVQFTCNEGYDLQGSKRITCMK 385
K SV T C +P P G + D + S ++++C +GY L GS TC+
Sbjct: 80 KNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCI- 138
Query: 386 VSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIK 445
+S W + PVC +C +G TS + + + KV +
Sbjct: 139 ISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFE 198
Query: 446 LAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPD-LIVSTNHQMWLLFQTDGSG 504
L E D VG Q + T +V + ++VS N ++ L +
Sbjct: 199 LVGEPSIYCTSKDD-QVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFR 257
Query: 505 SSLGF---KASYEEIEQGSCGDPGIPAYGR---------------REGSRFHHGDTLKFE 546
GF S+ + + + +P +P+ R R+ F G + +
Sbjct: 258 CQPGFGMKGPSHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYS 317
Query: 547 CQPAFELVGQKAITCQKNNQWSAKKPGC-VFSC-FFNFTSPSGVVLSP---------NYP 595
C+P ++L G + C WS P C V SC F P+G VL P ++
Sbjct: 318 CEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFV 377
Query: 596 EDYGNHL---HCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFS--- 649
D G L + +LA ES L + + V + K T PV G
Sbjct: 378 CDEGFQLKGSSASYCVLAGMES---LWNSSVPVCER------KSCETPPVPVNGMVHVIT 428
Query: 650 ----GNQLPSSITSSGH--VARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRF 703
G+++ S T +GH + + S +++ + CP+P +NG+
Sbjct: 429 DIHVGSRINYSCT-TGHRLIGHSSAECILSGNTAHWSMKPPICQQIFCPNPPAILNGRHT 487
Query: 704 GDSL---QLGSSISFLCDEG-----FLGTQGSETITCVLK-EGSVVWNSAVLRCEAPCG 753
G L G +S+ CD G TI + G+ VW+S RCE P G
Sbjct: 488 GTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCELPVG 546
Score = 51.6 bits (122), Expect = 1e-05
Identities = 100/451 (22%), Positives = 152/451 (33%), Gaps = 89/451 (19%)
Query: 138 TCGNPGRLPNGIQQG-STFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
+C NP NG+ +++YSC G+ L G + TC S N+ WD P
Sbjct: 95 SCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCII-SGNTVIWDNKTP-- 151
Query: 197 RADDACGGTLRGQSGIISSPHFPS---EYHNNADCTWTILAELGDTIALVFIDFQLEDGY 253
C + G I++ F S EY + T LG VF +L
Sbjct: 152 ----VCDRIICGLPPTIANGDFTSISREYFHYGSVV-TYHCNLGSRGKKVF---ELVGEP 203
Query: 254 DFLEVTGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKS 313
+ + +W S PAP N +G S + + + +E +
Sbjct: 204 SIYCTSKDDQVGIW----SGPAPQCIIPNKCTPPNVENGILVSDNRSL-FSLNEVVEFRC 258
Query: 314 R---GVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGI--PERGKRLGSDFRLGSSVQFT 368
+ G+K PS Q + S P P + ER +R +F G V ++
Sbjct: 259 QPGFGMK-GPSHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYS 317
Query: 369 CNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHL-RGPSGIITSPNFPIQYDN 427
C GYDL+GS + C D WS P C + CD L + P+G + P
Sbjct: 318 CEPGYDLRGSTYLHCTPQGD----WSPAAPRCEVKSCDDFLGQLPNGHVLFP-------- 365
Query: 428 NAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLI 487
+L+ G V D G + L G+S +
Sbjct: 366 -----------------------LNLQLGAKVDFVCDEG---------FQLKGSSASYCV 393
Query: 488 VSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGR-REGSRFHHGDTLKFE 546
++ +W +S E+ SC P +P G + H G + +
Sbjct: 394 LAGMESLW--------------NSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYS 439
Query: 547 CQPAFELVGQKAITC---QKNNQWSAKKPGC 574
C L+G + C WS K P C
Sbjct: 440 CTTGHRLIGHSSAECILSGNTAHWSMKPPIC 470
Score = 42.4 bits (98), Expect = 0.008
Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 6/65 (9%)
Query: 1907 SSCPEPAVPSNGVKTGER---YLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPL 1963
+ C P V NG+ + + +N+VV F+C+PG+ ++G +H+ C + +W P
Sbjct: 228 NKCTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQ--ALNKWEPELPS 284
Query: 1964 CIAQC 1968
C C
Sbjct: 285 CSRVC 289
Score = 40.4 bits (93), Expect = 0.031
Identities = 82/360 (22%), Positives = 120/360 (33%), Gaps = 82/360 (22%)
Query: 689 NECPDPGVPVNGKRFGDS---LQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAV 745
N+C P V NG D+ L + F C GF G +G + C + W +
Sbjct: 228 NKCTPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGF-GMKGPSHVKC---QALNKWEPEL 282
Query: 746 LRCEAPCG-------GHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIK-ITFDRF 797
C C T SPG FY SC +PGY ++ T+
Sbjct: 283 PSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFY----SC------EPGYDLRGSTYLHC 332
Query: 798 KTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRY 857
+ ++ R +G Q+P + L L D D GFQL+
Sbjct: 333 TPQGDWSPAAPRCEVKSCDDFLG-----QLPNGHVLFPLNLQLGAKVDFV-CDEGFQLKG 386
Query: 858 ETITL-----------------QSDHCLDPGIPVNGQRHG-NDFYVGALVTFSCDSGYTL 899
+ + + C P +PVNG H D +VG+ + +SC +G+ L
Sbjct: 387 SSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRL 446
Query: 900 SDGEPLEC---EPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIET 956
EC WS P C+ I P P T + +
Sbjct: 447 IGHSSAECILSGNTAHWSMKPPICQ------------QIFCPNPPAILNGRHTGTPLGDI 494
Query: 957 SHGKGVFFTFHTFHLESGHDYLLITE-----------NGSFTQPLRQLTGSRLPAPISAG 1005
+GK V +T H + G + LI E NG ++ P R P+ AG
Sbjct: 495 PYGKEVSYTCDP-HPDRGMTFNLIGESTIRRTSEPHGNGVWSSP-----APRCELPVGAG 548
Score = 35.0 bits (79), Expect = 1.3
Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 11/101 (10%)
Query: 98 GFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRLPNGIQQGST-FN 156
GFQL + S + + ++++ V +C P NG+ T +
Sbjct: 381 GFQLKGSSASYCVLAGMESL---------WNSSVPVCERKSCETPPVPVNGMVHVITDIH 431
Query: 157 LGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCR 197
+G ++ YSC G L GH+ C S N+A W P C+
Sbjct: 432 VGSRINYSCTTGHRLIGHSSAECIL-SGNTAHWSMKPPICQ 471
>gi|187960042 selectin E precursor [Homo sapiens]
Length = 610
Score = 177 bits (450), Expect = 1e-43
Identities = 123/418 (29%), Positives = 173/418 (41%), Gaps = 29/418 (6%)
Query: 2860 SCEA-GHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGL---VFSSS 2915
SC G + + TC+ + +SG + E +++C +P + +V S L ++SS
Sbjct: 147 SCSGHGECVETINNYTCKCDPGFSGLKCE-QIVNCTALESPEHGSLVCSHPLGNFSYNSS 205
Query: 2916 IVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGL----RLGNDFRYN 2971
C GY + + + C +G W+ P C V+ C PANG + F +N
Sbjct: 206 CSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWN 265
Query: 2972 KTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGS----- 3026
T T+ C G+ E L CT W+ KP CKA+ C+ NG V S
Sbjct: 266 TTCTFDCEEGF--ELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAG 323
Query: 3027 DFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGRRE---- 3082
+F + SS + C EG+ L PA C G WT ++P C C P RG
Sbjct: 324 EFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPS 383
Query: 3083 -DRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGI 3141
F Y SS FSC VL GS R C G W +P+C C P G+
Sbjct: 384 ASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTC---EAVRCDAVHQPPKGL 440
Query: 3142 QNNSQG----YQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPT 3197
+ + S+ F C++G+ L GST C W+ P C C P
Sbjct: 441 VRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPG 500
Query: 3198 HANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRPI 3255
N+ P G ++C EG++L GS RTC A G W+G P C S P+
Sbjct: 501 KINMSCSGEPVFGTVCKFACPEGWTL-NGSAARTCGATGHWSGLLPTCEAPTESNIPL 557
Score = 153 bits (387), Expect = 3e-36
Identities = 94/379 (24%), Positives = 148/379 (39%), Gaps = 30/379 (7%)
Query: 2588 CVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLG 2647
C + P+ S+ H + + + + CD GY + ++C ++G+WS
Sbjct: 180 CTALESPEHGSLVCSHPLGN------FSYNSSCSISCDRGYLPSSMETMQCMSSGEWSA- 232
Query: 2648 DSTPTCRIISCGELPIPPNG-----HRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANG 2702
P C ++ C + P NG G+ + T F C G+ L+G++ +C ++G
Sbjct: 233 -PIPACNVVECDAVTNPANGFVECFQNPGSFP-WNTTCTFDCEEGFELMGAQSLQCTSSG 290
Query: 2703 LWSGSEVRCLAGHCGTPEPIVNG-----HINGENYSYRGSVVYQCNAGFRLIGMSVRICQ 2757
W + C A C NG H ++++ S + C GF L G + C
Sbjct: 291 NWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECT 350
Query: 2758 QDHHWSGKTPFCVLVSCGHPGSPPHSQMS-----GDSYTVGAVVRYSCIGKRTLVGNSTR 2812
W+ + P C C +P M+ S+ G+ +SC L G+
Sbjct: 351 TQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRL 410
Query: 2813 MCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDS----FDPGTVMRFSCEAGHVLR 2868
CG G W P C P P +R S F + FSCE G L
Sbjct: 411 QCGPTGEWDNEKPTCEAVRCDAVHQP--PKGLVRCAHSPIGEFTYKSSCAFSCEEGFELH 468
Query: 2869 GSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATG 2928
GS++ C + G W+ P C V+ C + P + S VF + + C EG+ G
Sbjct: 469 GSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNG 528
Query: 2929 LLSRHCSVNGTWTGSDPEC 2947
+R C G W+G P C
Sbjct: 529 SAARTCGATGHWSGLLPTC 547
Score = 151 bits (381), Expect = 1e-35
Identities = 112/406 (27%), Positives = 161/406 (39%), Gaps = 43/406 (10%)
Query: 2468 CSLPRAPLHGFI-----LGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEA 2522
C+ +P HG + LG S SI C+ GY C + WS
Sbjct: 180 CTALESPEHGSLVCSHPLGNFSYNSSCSI--SCDRGYLPSSMETMQCMSSGE----WSAP 233
Query: 2523 IPLCQALSCGLPEAPKNGMV----FGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGL 2578
IP C + C P NG V + T + C EG+ L GA+ + +C +G
Sbjct: 234 IPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELM-GAQ-SLQCTSSGN 291
Query: 2579 WSNRNVPPQCVPVTC-----PDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQ 2633
W N P C VTC P S+ H ++ F++ C+ G+ G
Sbjct: 292 WDNEK--PTCKAVTCRAVRQPQNGSVRCSHSP-----AGEFTFKSSCNFTCEEGFMLQGP 344
Query: 2634 RVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSV-----YGATAIFSCNSGY 2688
+ C G+W+ P C C L P G+ S YG++ FSC G+
Sbjct: 345 AQVECTTQGQWT--QQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGF 402
Query: 2689 TLVGSRVRECMANGLWSGSEVRCLAGHCGT----PEPIVN-GHINGENYSYRGSVVYQCN 2743
L GS+ +C G W + C A C P+ +V H ++Y+ S + C
Sbjct: 403 VLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCE 462
Query: 2744 AGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTV-GAVVRYSCIG 2802
GF L G + C W+ + P C +V C P MS V G V +++C
Sbjct: 463 EGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPE 522
Query: 2803 KRTLVGNSTRMCGLDGHWTGSLPHCSG-TSVGVCGDPGIPAHGIRL 2847
TL G++ R CG GHW+G LP C T + G+ A G+ L
Sbjct: 523 GWTLNGSAARTCGATGHWSGLLPTCEAPTESNIPLVAGLSAAGLSL 568
Score = 63.2 bits (152), Expect = 4e-09
Identities = 58/280 (20%), Positives = 100/280 (35%), Gaps = 42/280 (15%)
Query: 155 FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQSGIIS 214
F+ SC+ G+ + C + E W P+P+C + C +G +
Sbjct: 200 FSYNSSCSISCDRGYLPSSMETMQCMSSGE----WSAPIPACNVVE-CDAVTNPANGFVE 254
Query: 215 SPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTE--GSSLWFTGAS 272
P + N CT F E+G++ + + S W
Sbjct: 255 CFQNPGSFPWNTTCT-----------------FDCEEGFELMGAQSLQCTSSGNWDN--- 294
Query: 273 LPAPVISSKNWLRLHFTSDGNHR-QRGFSAQYQVKKQIELKSRGVKLMPSKDNSQKTSV- 330
P + + +G+ R + ++ K ++ + T+
Sbjct: 295 -EKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQG 353
Query: 331 --LTQVGVSQGHNMCPDPGIPERG-----KRLGSDFRLGSSVQFTCNEGYDLQGSKRITC 383
Q+ V + C PERG FR GSS +F+C +G+ L+GSKR+ C
Sbjct: 354 QWTQQIPVCEAFQ-CTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQC 412
Query: 384 MKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPI 423
+ W + +P C A CDA + P G++ + PI
Sbjct: 413 GPTGE----WDNEKPTCEAVRCDAVHQPPKGLVRCAHSPI 448
Score = 60.5 bits (145), Expect = 3e-08
Identities = 76/288 (26%), Positives = 108/288 (37%), Gaps = 48/288 (16%)
Query: 1207 ELIKCEDPGTPKFGYKV--HDEGHFA-GSSVSFSCDPGYSLRGSEELLCLSGERRTWDRP 1263
+++ C +P+ G V H G+F+ SS S SCD GY E + C+S W P
Sbjct: 176 QIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGE--WSAP 233
Query: 1264 LPTC-VAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTI-GLHFLVFDTEE 1321
+P C V EC V +G V P + N C T + E G + G L +
Sbjct: 234 IPACNVVECDA-VTNPANGFVECFQNPGSFPWNTTC--TFDCEEGFELMGAQSLQCTSSG 290
Query: 1322 VHDVLRIWDG--PVESGVLLKELSGP--ALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQ- 1376
WD P V + + P + HS + S +F T ++GF +Q
Sbjct: 291 N------WDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNF-TCEEGFMLQG 343
Query: 1377 ---------------FSVSTATSCNDPGIPQNG------SRSGDSWEAGDSTVFQCDPGY 1415
V A C P+ G S SG S+ G S F C+ G+
Sbjct: 344 PAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASG-SFRYGSSCEFSCEQGF 402
Query: 1416 ALQGSAEISCVKIENRFFWQPSPPTCIA-PCGGDLTGPSGVILSPNYP 1462
L+GS + C W PTC A C P G++ + P
Sbjct: 403 VLKGSKRLQCGPTGE---WDNEKPTCEAVRCDAVHQPPKGLVRCAHSP 447
Score = 57.8 bits (138), Expect = 2e-07
Identities = 69/271 (25%), Positives = 99/271 (36%), Gaps = 30/271 (11%)
Query: 1055 FGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRC-VAECG---NSVTGTQGTLL 1110
F + + SC GY + C+ WS+P+P C V EC N G
Sbjct: 200 FSYNSSCSISCDRGYLPSSMETMQCMSSGE--WSAPIPACNVVECDAVTNPANGFVECFQ 257
Query: 1111 SP-NFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLK------VYDGNNNSARL 1163
+P +FP N +C + + +Q + +E K V N S R
Sbjct: 258 NPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRC 317
Query: 1164 LGVFSHSEMMGVTLNSTSS-----SLWLDFITDAENTSKG-FELHFSSFELIKCEDPGTP 1217
SHS T S+ + L E T++G + E +C P
Sbjct: 318 ----SHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNP 373
Query: 1218 KFGYK---VHDEGHFA-GSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECGG 1273
+ GY G F GSS FSC+ G+ L+GS+ L C G WD PTC A
Sbjct: 374 ERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQC--GPTGEWDNEKPTCEAVRCD 431
Query: 1274 TVRGEVSGQVLSPGYP-APYEHNLNCIWTIE 1303
V G V P + + +C ++ E
Sbjct: 432 AVHQPPKGLVRCAHSPIGEFTYKSSCAFSCE 462
Score = 54.3 bits (129), Expect = 2e-06
Identities = 89/409 (21%), Positives = 144/409 (35%), Gaps = 79/409 (19%)
Query: 882 DFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEAL-CGGFIQGSSGTILSPGF 940
+F + + SCD GY S E ++C + +WS +P+C + C ++G +
Sbjct: 199 NFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQN 258
Query: 941 PDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPA 1000
P +P N C TF E G + L G++
Sbjct: 259 PGSFPWNTTC-----------------TFDCEEGFE----------------LMGAQSLQ 285
Query: 1001 PISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAY-SIR----KGLQF 1055
S+G + N + ++ C P S+R +F
Sbjct: 286 CTSSGNWDNEKPTCKAVT--------------------CRAVRQPQNGSVRCSHSPAGEF 325
Query: 1056 GVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVA-EC---GNSVTGTQGTLLS 1111
+ F+C G+ L+G A++ C + W+ +P C A +C N G L S
Sbjct: 326 TFKSSCNFTCEEGFMLQGPAQVECT--TQGQWTQQIPVCEAFQCTALSNPERGYMNCLPS 383
Query: 1112 PNFPVNYNNNHE--CIYSIQTQPGKGIQLKARAFELSEGDVLKVY--DGNNNSARLLGVF 1167
+ Y ++ E C + K +Q +E + D + + L
Sbjct: 384 ASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRC 443
Query: 1168 SHSEMMGVTLNST-----SSSLWLDFITDAENTSKG-FELHFSSFELIKCEDPGTP-KFG 1220
+HS + T S+ L T E TS+G + S +++KC P K
Sbjct: 444 AHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKIN 503
Query: 1221 YKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVA 1269
E F G+ F+C G++L GS C G W LPTC A
Sbjct: 504 MSCSGEPVF-GTVCKFACPEGWTLNGSAARTC--GATGHWSGLLPTCEA 549
Score = 48.9 bits (115), Expect = 9e-05
Identities = 65/269 (24%), Positives = 105/269 (39%), Gaps = 41/269 (15%)
Query: 150 QQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQ 209
Q +F + C GF L G L C +S WD P+C+A C + Q
Sbjct: 257 QNPGSFPWNTTCTFDCEEGFELMGAQSLQC----TSSGNWDNEKPTCKAV-TCRAVRQPQ 311
Query: 210 SGIISSPHFPS-EYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSSLW- 267
+G + H P+ E+ + C +T E G F L+ G +E T T+G W
Sbjct: 312 NGSVRCSHSPAGEFTFKSSCNFT--CEEG---------FMLQ-GPAQVECT-TQGQ--WT 356
Query: 268 --------FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELK-SRGVKL 318
F +L P N L ++ G+ R G S ++ ++ LK S+ ++
Sbjct: 357 QQIPVCEAFQCTALSNPERGYMNCLP---SASGSFRY-GSSCEFSCEQGFVLKGSKRLQC 412
Query: 319 MPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGS 378
P+ + + V H P G+ +F SS F+C EG++L GS
Sbjct: 413 GPTGEWDNEKPTCEAVRCDAVHQ--PPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGS 470
Query: 379 KRITCMKVSDMFAAWSDHRPVCRARMCDA 407
++ C W++ P C+ C +
Sbjct: 471 TQLECTSQGQ----WTEEVPSCQVVKCSS 495
Score = 48.1 bits (113), Expect = 1e-04
Identities = 50/228 (21%), Positives = 78/228 (34%), Gaps = 63/228 (27%)
Query: 1575 KLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAP-CGGQYVGSDGVVLSP 1633
+ GSS + C G+ ++G+ L C GP G+ W+N +P C A C + G+V
Sbjct: 389 RYGSSCEFSCEQGFVLKGSKRLQC--GPTGE--WDNEKPTCEAVRCDAVHQPPKGLVRCA 444
Query: 1634 NYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHT 1693
+ P G+F + + E + H ++L + G T
Sbjct: 445 HSP---------------------IGEFTYKSSCAFSCEEGFELHGS-TQLECTSQGQWT 482
Query: 1694 GESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPEP-RYGKRLGSDFS 1752
E VP +CSS+ P + +
Sbjct: 483 EE-------------------------------VPSCQVVKCSSLAVPGKINMSCSGEPV 511
Query: 1753 VGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNL 1800
G + +F C G+ L GS C GA W+ PTC P N+
Sbjct: 512 FGTVCKFACPEGWTLNGSAARTC----GATGHWSGLLPTCEAPTESNI 555
Score = 45.8 bits (107), Expect = 7e-04
Identities = 65/280 (23%), Positives = 102/280 (36%), Gaps = 48/280 (17%)
Query: 1578 SSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTA-PCGGQYVGSDGVVLSPNYP 1636
++ T+ C G+E+ G +L C + W+N +P C A C +G V + P
Sbjct: 266 TTCTFDCEEGFELMGAQSLQCTSSGN----WDNEKPTCKAVTCRAVRQPQNGSVRCSHSP 321
Query: 1637 Q---------NYTSGQICLYFVTVPKDYVVFGQF--------AFFHTALNDVVEVHDGHS 1679
N+T + + + GQ+ AF TAL++
Sbjct: 322 AGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNP------ER 375
Query: 1680 QHSRLLSSLSGSHT-GESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSV 1738
+ L S SGS G S + ++K S + G P A +C +V
Sbjct: 376 GYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWD--NEKPTCEAVRCDAV 433
Query: 1739 PEPRYG------KRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC 1792
+P G +G +F+ + F C G+ L GS ++EC + QW P+C
Sbjct: 434 HQPPKGLVRCAHSPIG-EFTYKSSCAFSCEEGFELHGSTQLECT----SQGQWTEEVPSC 488
Query: 1793 -VVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEG 1831
VV C + + G P V K PEG
Sbjct: 489 QVVKCSSLAVPGKINMSCSGEP-----VFGTVCKFACPEG 523
Score = 45.4 bits (106), Expect = 0.001
Identities = 63/284 (22%), Positives = 91/284 (32%), Gaps = 59/284 (20%)
Query: 349 PERGKRLGS----DFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARM 404
PE G + S +F SS +C+ GY + + CM + WS P C
Sbjct: 186 PEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGE----WSAPIPACNVVE 241
Query: 405 CDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYD-----T 459
CDA +G + P + N C FD E G++ +
Sbjct: 242 CDAVTNPANGFVECFQNPGSFPWNTTCT------------------FDCEEGFELMGAQS 283
Query: 460 LTVGDGGQDGDQKTVLYILTGTSV---PDLIVSTNHQMWLLFQTDGS-------GSSLGF 509
L G ++K +T +V + V +H F S G L
Sbjct: 284 LQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQG 343
Query: 510 KASYEEIEQGS------------CGDPGIPAYGRRE-----GSRFHHGDTLKFECQPAFE 552
A E QG C P G F +G + +F C+ F
Sbjct: 344 PAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFV 403
Query: 553 LVGQKAITCQKNNQWSAKKPGC-VFSCFFNFTSPSGVVLSPNYP 595
L G K + C +W +KP C C P G+V + P
Sbjct: 404 LKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSP 447
Score = 41.6 bits (96), Expect = 0.014
Identities = 71/290 (24%), Positives = 98/290 (33%), Gaps = 48/290 (16%)
Query: 1928 NDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLC-IAQCGGTVEEMEGVILSPGFPG 1986
N S C+ GY + CM W+ P P C + +C G + PG
Sbjct: 203 NSSCSISCDRGYLPSSMETMQCMSSG--EWSAPIPACNVVECDAVTNPANGFVECFQNPG 260
Query: 1987 NYPSN----MDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSE 2042
++P N DC L GA Q L ++ N D T + + + +
Sbjct: 261 SFPWNTTCTFDCEEGFEL---MGA--QSLQCTSSGNWD------NEKPTCKAVTCRAVRQ 309
Query: 2043 LPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSFLRGFDLSELERTNSTPP 2102
+ + SH F S N F E GF L + T
Sbjct: 310 PQNGSVRCSHSPAGEFTFKSSCN---FTCE--------------EGFMLQGPAQVECT-- 350
Query: 2103 VAASYVWDLD-PGCEAYELQECPDPEP-FANGIVRGAG-YNVGQSVTFECLPGYQLTGHP 2159
W P CEA++ +PE + N + +G + G S F C G+ L G
Sbjct: 351 --TQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSK 408
Query: 2160 VLTCQHGTNRNWDHPLPKCE-VPCGGNITSSNGTV---YSPGFPSPYSSS 2205
L C G WD+ P CE V C G V +SP Y SS
Sbjct: 409 RLQC--GPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSS 456
Score = 40.0 bits (92), Expect = 0.041
Identities = 40/149 (26%), Positives = 58/149 (38%), Gaps = 20/149 (13%)
Query: 2072 EYQDLTYSHQISSFLRGF------DLSELERTNSTPPVAASYVWDLD-PGCEAYELQECP 2124
E+ L SH + +F D L + T +S W P C E
Sbjct: 187 EHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVT 246
Query: 2125 DPEPFANGIVR----GAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCE- 2179
+P ANG V + + TF+C G++L G L C ++ NWD+ P C+
Sbjct: 247 NP---ANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCT--SSGNWDNEKPTCKA 301
Query: 2180 VPCGGNITSSNGTV---YSPGFPSPYSSS 2205
V C NG+V +SP + SS
Sbjct: 302 VTCRAVRQPQNGSVRCSHSPAGEFTFKSS 330
Score = 36.6 bits (83), Expect = 0.45
Identities = 64/293 (21%), Positives = 101/293 (34%), Gaps = 70/293 (23%)
Query: 1727 VPRTSATQCSSVPEPRYG-----KRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGA 1781
+P + +C +V P G + GS F F+C G+ L G+ ++C +
Sbjct: 234 IPACNVVECDAVTNPANGFVECFQNPGS-FPWNTTCTFDCEEGFELMGAQSLQCT----S 288
Query: 1782 LAQWNVSAPTC-VVPCGGNLTERRGTIL---SPGFPEPYLNSLNCVWKIVVPEGAGIQIQ 1837
W+ PTC V C + G++ SP + +S N EG +Q
Sbjct: 289 SGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCN----FTCEEGFMLQGP 344
Query: 1838 V-VSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAG 1896
V T+ W + + +F T AL N Y + SA+G
Sbjct: 345 AQVECTTQGQW---------TQQIPVCEAFQCT---ALSNPERG------YMNCLPSASG 386
Query: 1897 FHLEYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRR 1956
Y SSC F CE G+ L+G + C G
Sbjct: 387 -SFRYG----SSC----------------------EFSCEQGFVLKGSKRLQC--GPTGE 417
Query: 1957 WNYPPPLCIA-QCGGTVEEMEGVILSPGFP-GNYPSNMDCSWKIALPVGFGAH 2007
W+ P C A +C + +G++ P G + C++ + GF H
Sbjct: 418 WDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAF--SCEEGFELH 468
Score = 34.7 bits (78), Expect = 1.7
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 11/78 (14%)
Query: 2109 WDLD-PGCEAYELQECPDPEPFANGIVRGAGYNVGQ-----SVTFECLPGYQLTGHPVLT 2162
WD + P CEA P G+VR A +G+ S F C G++L G L
Sbjct: 418 WDNEKPTCEAVRCDAVHQPP---KGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLE 474
Query: 2163 CQHGTNRNWDHPLPKCEV 2180
C + W +P C+V
Sbjct: 475 CT--SQGQWTEEVPSCQV 490
Score = 33.1 bits (74), Expect = 5.0
Identities = 17/45 (37%), Positives = 19/45 (42%), Gaps = 2/45 (4%)
Query: 2142 GQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNI 2186
G F C G+ L G TC G +W LP CE P NI
Sbjct: 513 GTVCKFACPEGWTLNGSAARTC--GATGHWSGLLPTCEAPTESNI 555
>gi|62739186 complement factor H isoform a precursor [Homo sapiens]
Length = 1231
Score = 166 bits (419), Expect = 5e-40
Identities = 250/1035 (24%), Positives = 409/1035 (39%), Gaps = 155/1035 (14%)
Query: 2291 LTKCPPPTILPNAEVVTE----NEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEG 2346
+ KC P T N ++V+ + E++ G VR+ C G+ + G+E + C + E
Sbjct: 143 VVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEK 202
Query: 2347 PPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEK 2406
P + E+ C + +++ S I + +FQ + Y S + +E
Sbjct: 203 PKCV-EISCKSPDVINGSP--ISQKIIYKENERFQ-----YKCNMGYEYSERGDAVCTES 254
Query: 2407 QYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYS-- 2464
+ + S +P + +G+YS I + + + + + +G + +
Sbjct: 255 GWRPLPSCEEKSCDNPYIP--NGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTST 312
Query: 2465 ----APYCSLPRAPL----HGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGY 2516
AP C+L HG + + +P + G Y H +
Sbjct: 313 GWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHI 372
Query: 2517 HL----WSEAIPLCQALSCGLPEAPKNG--MVFGKEYTVGTKAMYSCSEGYHLQAGAEAT 2570
H WS A+P + C P +NG G+++ G +C GY L A+ T
Sbjct: 373 HCTQDGWSPAVPCLR--KCYFPYL-ENGYNQNHGRKFVQGKSIDVACHPGYALPK-AQTT 428
Query: 2571 AECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQF--QAQLMLICDPGY 2628
C++ G WS P+C+ V SSI +E+G I E+QY + + + C GY
Sbjct: 429 VTCMENG-WS---PTPRCIRVKTCSKSSIDIENG---FISESQYTYALKEKAKYQCKLGY 481
Query: 2629 YYTGQRV---IRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVY--GATAIFS 2683
I C +G WS + PTC I SC ++P+ N + + T +
Sbjct: 482 VTADGETSGSITCGKDG-WS---AQPTC-IKSC-DIPVFMNARTKNDFTWFKLNDTLDYE 535
Query: 2684 CNSGY-----TLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHI----NGENYSY 2734
C+ GY + GS V C NG WS + C C P+ ++ H+ + Y
Sbjct: 536 CHDGYESNTGSTTGSIV--CGYNG-WSDLPI-CYERECELPK--IDVHLVPDRKKDQYKV 589
Query: 2735 RGSVVYQCNAGFRLIGMSVRICQQDHHW--SGKTPFC--VLVSCGHPGSPPHSQMSG--- 2787
+ + C GF ++G + C +H+ S P C + SCG PP ++G
Sbjct: 590 GEVLKFSCKPGFTIVGPNSVQC---YHFGLSPDLPICKEQVQSCG----PPPELLNGNVK 642
Query: 2788 ----DSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAH 2843
+ Y VV Y C + + G + C +DG WT +LP C CGD H
Sbjct: 643 EKTKEEYGHSEVVEYYCNPRFLMKGPNKIQC-VDGEWT-TLPVCI-VEESTCGDIPELEH 699
Query: 2844 GIRLGDS--FDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSN 2901
G S + G + F+C + G TC +G W+ P+C I SN
Sbjct: 700 GWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-IHGVWT-QLPQCVAIDKLKKCKSSN 757
Query: 2902 ARVVFSDGLV------FSSSIVYECR--EGYYATGLLSRHCSVNGTWTGSDPECLVINCG 2953
++ + L +S+I Y CR EG+ T +NG W DPE +NC
Sbjct: 758 L-IILEEHLKNKKEFDHNSNIRYRCRGKEGWIHT------VCINGRW---DPE---VNCS 804
Query: 2954 ---------DPGIP-ANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGT 3003
P IP ++ + ++R + V+ C Y+++ ++C KD W
Sbjct: 805 MAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEG--EEITC-KDGRWQSI 861
Query: 3004 KPVCKALMCKPPPLIPNGKVVGS-----DFMWGSSVTYACLEGYQLSLPAVFTCEGNGSW 3058
+ + C PP I +G + S + G+ ++Y C G+++S TC G W
Sbjct: 862 PLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCY-MGKW 920
Query: 3059 TGELPQCFPVFCGDPGVPSRG--RREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTW 3116
+ PQC + C P S G + Y V++ C + G C + W
Sbjct: 921 SSP-PQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGE-KW 978
Query: 3117 SGTQPSCIDPTLTTCADPGVPQF----GIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTC 3172
S PSCI T C +P F + Y+ G V + C Y + G++ TC
Sbjct: 979 S-HPPSCIK---TDCL--SLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTC 1032
Query: 3173 LPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPS--MGYTLIYSCQEGFSLKGGSEHR 3230
+ N W+G P C C P T +A + + + G + Y C+ + + G E
Sbjct: 1033 I-NSRWTGR-PTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEE-- 1088
Query: 3231 TCKADGSWTGKPPIC 3245
+G+WT +PP C
Sbjct: 1089 VMCLNGNWT-EPPQC 1102
Score = 145 bits (367), Expect = 5e-34
Identities = 192/743 (25%), Positives = 289/743 (38%), Gaps = 96/743 (12%)
Query: 2493 FGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPL--CQALSCGLPEAPKNG---MVFGKEY 2547
+ C GYR +G+ + +C + W PL CQ CG P G + G +
Sbjct: 50 YKCRPGYRSLGNVIMVCRKGE-----WVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVF 104
Query: 2548 TVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVP----PQCVPVTCPD---VSSIS 2600
G KA+Y+C+EGY L G EC DT W+N ++P +C+PVT P+ + S +
Sbjct: 105 EYGVKAVYTCNEGYQL-LGEINYREC-DTDGWTN-DIPICEVVKCLPVTAPENGKIVSSA 161
Query: 2601 VEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGE 2660
+E R +Y F + +C+ GY G + C +G WS P C ISC +
Sbjct: 162 MEPDR-------EYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWS--KEKPKCVEISC-K 211
Query: 2661 LPIPPNGHRIGTLSVYGATAIF--SCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGT 2718
P NG I +Y F CN GY C +G W C C
Sbjct: 212 SPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WRPLP-SCEEKSCDN 269
Query: 2719 PEPIVNGHINGENYSYR--GSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGH 2776
P I NG + +R + YQC GF W P C L C +
Sbjct: 270 PY-IPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWI-PAPRCTLKPCDY 327
Query: 2777 P----GSPPHSQMSGDSY--TVGAVVRYSCIGKRTLVGNS---TRMCGLDGHWTGSLPHC 2827
P G H M + VG Y C S C DG W+ ++P
Sbjct: 328 PDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVP-- 384
Query: 2828 SGTSVGVCGDPGIP-AHGIRLGDSFDPGTVMRFSCEAGHVL-RGSSERTCQANGSWSGSQ 2885
+ C P + + G F G + +C G+ L + + TC NG WS +
Sbjct: 385 ---CLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMENG-WSPT- 439
Query: 2886 PECGVISCGNPGTPSNARVVFSDGLVFSSSIV--------YECREGYY-ATGLLSRHCSV 2936
P C + T S + + +G + S Y+C+ GY A G S +
Sbjct: 440 PRCIRVK-----TCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSGSITC 494
Query: 2937 NGTWTGSDPECLVINCGDPGIPANGLRLGND---FRYNKTVTYQCVPGYMMESHRVSVLS 2993
+ P C + +C P R ND F+ N T+ Y+C GY + +
Sbjct: 495 GKDGWSAQPTC-IKSCDIPVF--MNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSI 551
Query: 2994 CTKDRTWNGTKPVCKALMCKPPP----LIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAV 3049
W+ P+C C+ P L+P+ K + G + ++C G+ + P
Sbjct: 552 VCGYNGWSDL-PICYERECELPKIDVHLVPDRK--KDQYKVGEVLKFSCKPGFTIVGPNS 608
Query: 3050 FTCEGNGSWTGELPQCFPVF--CGDPGVPSRGRREDR---GFSYRSSVSFSCHPPLVLVG 3104
C G + +LP C CG P G +++ + + V + C+P ++ G
Sbjct: 609 VQCYHFG-LSPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKG 667
Query: 3105 SPRRFCQSDGTWSGTQPSCIDPTLTTCAD-PGVPQFGIQNNSQGYQVGSTVLFRCQKGYL 3163
P + DG W+ T P CI +TC D P + Q +S Y G +V F C + +
Sbjct: 668 -PNKIQCVDGEWT-TLPVCIVEE-STCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFT 724
Query: 3164 LQGSTTRTCLPNLTWSGTPPDCV 3186
+ G + TC+ + W+ P CV
Sbjct: 725 MIGHRSITCIHGV-WTQL-PQCV 745
Score = 143 bits (360), Expect = 3e-33
Identities = 201/805 (24%), Positives = 315/805 (39%), Gaps = 95/805 (11%)
Query: 2488 GGSIHFGCNAGYRLV-GHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAP-KNGMVFGK 2545
G SI C+ GY L + C + WS + +C +NG +
Sbjct: 409 GKSIDVACHPGYALPKAQTTVTCMENG-----WSPTPRCIRVKTCSKSSIDIENGFISES 463
Query: 2546 EYTVGTK--AMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEH 2603
+YT K A Y C GY G + + WS + P C+ +C D+ +
Sbjct: 464 QYTYALKEKAKYQCKLGYVTADGETSGSITCGKDGWSAQ---PTCIK-SC-DIPVFM--N 516
Query: 2604 GRWRLIFETQYQFQAQLMLICDPGYYY-TGQRV--IRCQANGKWSLGDSTPTCRIISCGE 2660
R + F T ++ L C GY TG I C NG WS P C C E
Sbjct: 517 ARTKNDF-TWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNG-WS---DLPICYEREC-E 570
Query: 2661 LP-----IPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEV-RCLAG 2714
LP + P+ R G FSC G+T+VG +C GL + +
Sbjct: 571 LPKIDVHLVPD--RKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGLSPDLPICKEQVQ 628
Query: 2715 HCGTPEPIVNGHING---ENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVL 2771
CG P ++NG++ E Y + V Y CN F + G + C D W+ P C++
Sbjct: 629 SCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV-DGEWT-TLPVCIV 686
Query: 2772 V--SCGHPGSPPH--SQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHC 2827
+CG H +Q+S Y G V ++C T++G+ + C + G WT LP C
Sbjct: 687 EESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-IHGVWT-QLPQC 744
Query: 2828 SGTS-VGVCGDPG--IPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGS 2884
+ C I ++ FD + +R+ C G C NG W
Sbjct: 745 VAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKE---GWIHTVC-INGRWD-P 799
Query: 2885 QPECGVISCG----NPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTW 2940
+ C + P P++ + + + C+E Y C +G W
Sbjct: 800 EVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCK-DGRW 858
Query: 2941 TGSDPECLV-INCGDP-----GIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSC 2994
S P C+ I C P G + + + ++Y C G+ + +
Sbjct: 859 Q-SIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYM 917
Query: 2995 TKDRTWNGTKPVCKALMCKPPPLIPNGKV--VGSDFMWGSSVTYACLEGYQLSLPAVFTC 3052
K W+ + P C+ L CK PP I +G V + + +G VTY C EG+ + PA+ C
Sbjct: 918 GK---WS-SPPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKC 973
Query: 3053 EGNGSWTGELPQCFPVFC-----GDPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPR 3107
G W+ P C C + +P G ++D + V+++C + G+
Sbjct: 974 LGE-KWS-HPPSCIKTDCLSLPSFENAIP-MGEKKD-VYKAGEQVTYTCATYYKMDGASN 1029
Query: 3108 RFCQSDGTWSGTQPSCIDPTLTTCADPGVPQ--FGIQNNSQGYQVGSTVLFRCQKGYLLQ 3165
C + W+G +P+C D T+C +P Q + + Y G V ++C+ Y +
Sbjct: 1030 VTC-INSRWTG-RPTCRD---TSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMF 1084
Query: 3166 GSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPSMGY----TLIYSCQEGF 3221
G CL N W+ PP C + P N P Y ++ Y CQ +
Sbjct: 1085 GDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLY 1142
Query: 3222 SLKGGSEHRTCKADGSWTGKPPICL 3246
L+ G++ TC+ +G W+ +PP CL
Sbjct: 1143 QLE-GNKRITCR-NGQWS-EPPKCL 1164
Score = 134 bits (336), Expect = 2e-30
Identities = 142/577 (24%), Positives = 230/577 (39%), Gaps = 66/577 (11%)
Query: 2711 CLAGHCGTPEP-----IVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGK 2765
C+A C P I+ G + + Y +Y+C G+R +G + +C++ W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGE-WVAL 74
Query: 2766 TPF--CVLVSCGHPGSPPHSQMS---GDSYTVGAVVRYSCIGKRTLVGN-STRMCGLDGH 2819
P C CGHPG P + G+ + G Y+C L+G + R C DG
Sbjct: 75 NPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG- 133
Query: 2820 WTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDP------GTVMRFSCEAGHVLRGSSER 2873
WT +P C V C P +G + + +P G +RF C +G+ + G E
Sbjct: 134 WTNDIPICE---VVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEM 190
Query: 2874 TCQANGSWSGSQPECGVISCGNP----GTPSNARVVFSDGLVFSSSIVYECREGYYATGL 2929
C +G WS +P+C ISC +P G+P + ++++ + F Y+C GY +
Sbjct: 191 HCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQ----YKCNMGYEYSER 246
Query: 2930 LSRHCSVNGTWTGSDPECLVINCGDPGIPANG----LRLGNDFRYNKTVTYQCVPGYMME 2985
C+ +G W P C +C +P IP NG LR+ + R +TYQC G+
Sbjct: 247 GDAVCTESG-WRPL-PSCEEKSCDNPYIP-NGDYSPLRIKH--RTGDEITYQCRNGF-YP 300
Query: 2986 SHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGS------DFMWGSSVTYACL 3039
+ R + CT T P C C P + G + G +Y C
Sbjct: 301 ATRGNTAKCTS--TGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCD 358
Query: 3040 EGYQLSLPAVFT---CEGNGSWTGELP---QCFPVFCGDPGVPSRGRREDRGFSYRSSVS 3093
E ++ + + C +G W+ +P +C+ + + + GR+ F S+
Sbjct: 359 EHFETPSGSYWDHIHCTQDG-WSPAVPCLRKCYFPYLENGYNQNHGRK----FVQGKSID 413
Query: 3094 FSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVP-QFGIQNNSQ-GYQVG 3151
+CHP L + + WS T P CI + TC+ + + G + SQ Y +
Sbjct: 414 VACHPGYALPKAQTTVTCMENGWSPT-PRCI--RVKTCSKSSIDIENGFISESQYTYALK 470
Query: 3152 STVLFRCQKGYL-LQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPSMG 3210
++C+ GY+ G T+ + P C+ C P +
Sbjct: 471 EKAKYQCKLGYVTADGETSGSITCGKDGWSAQPTCI-KSCDIPVFMNARTKNDFTWFKLN 529
Query: 3211 YTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLE 3247
TL Y C +G+ GS + + PIC E
Sbjct: 530 DTLDYECHDGYESNTGSTTGSIVCGYNGWSDLPICYE 566
Score = 122 bits (305), Expect = 8e-27
Identities = 182/776 (23%), Positives = 290/776 (37%), Gaps = 96/776 (12%)
Query: 2518 LWSEAIPLCQALSCG-LPEAPKNGMVFG----KEYTVGTKAMYSCSEGYHLQAGAEATAE 2572
LW+ +C A C LP ++ G + Y GT+A+Y C GY
Sbjct: 12 LWA----ICVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCR 67
Query: 2573 CLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTG 2632
G W N +C C G + L +++ + + C+ GY G
Sbjct: 68 ---KGEWVALNPLRKCQKRPCGHPGD--TPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLG 122
Query: 2633 QRVIR-CQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSV------YGATAIFSCN 2685
+ R C +G W+ + P C ++ C + P NG + + +G F CN
Sbjct: 123 EINYRECDTDG-WT--NDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCN 179
Query: 2686 SGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGS--VVYQCN 2743
SGY + G C +G WS + +C+ C +P+ ++NG + Y+ + Y+CN
Sbjct: 180 SGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPD-VINGSPISQKIIYKENERFQYKCN 238
Query: 2744 AGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGD------SYTVGAVVR 2797
G+ +C + W P C SC +P P +GD + G +
Sbjct: 239 MGYEYSERGDAVCTES-GWR-PLPSCEEKSCDNPYIP-----NGDYSPLRIKHRTGDEIT 291
Query: 2798 YSC-IGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDP--- 2853
Y C G +T C G W + P C ++ C P I G+ + P
Sbjct: 292 YQCRNGFYPATRGNTAKCTSTG-WIPA-PRC---TLKPCDYPDIKHGGLYHENMRRPYFP 346
Query: 2854 ---GTVMRFSCEAGHVLRGSS---ERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFS 2907
G + C+ S C +G WS + P C + C P +
Sbjct: 347 VAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVP-C-LRKCYFPYLENGYNQNHG 403
Query: 2908 DGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECL-VINCGDPGIP-ANGLRLG 2965
V SI C GY + + W+ + P C+ V C I NG
Sbjct: 404 RKFVQGKSIDVACHPGYALPKAQTTVTCMENGWSPT-PRCIRVKTCSKSSIDIENGFISE 462
Query: 2966 NDFRY--NKTVTYQCVPGYMMESHRVS-VLSCTKDRTWNGTKPVCKALMCKPPPLIPNGK 3022
+ + Y + YQC GY+ S ++C KD W+ +P C + P+ N +
Sbjct: 463 SQYTYALKEKAKYQCKLGYVTADGETSGSITCGKD-GWS-AQPTC--IKSCDIPVFMNAR 518
Query: 3023 VVGSDFMW---GSSVTYACLEGYQL---SLPAVFTCEGNGSWTGELPQCFPVFCGDPGVP 3076
+DF W ++ Y C +GY+ S C NG W+ +LP C+ C P +
Sbjct: 519 -TKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNG-WS-DLPICYERECELPKID 575
Query: 3077 SR---GRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCAD 3133
R++D+ + + FSC P +VG C G S P C + +
Sbjct: 576 VHLVPDRKKDQ-YKVGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPP 633
Query: 3134 PGVPQFGI-QNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQ 3192
P + + + + Y V + C +L++G C+ W+ T P C+
Sbjct: 634 PELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVDG-EWT-TLPVCIVEESTC 691
Query: 3193 PETPTHANVGALDLPSMGY----TLIYSCQEGFSLKGGSEHR--TCKADGSWTGKP 3242
+ P G L S Y ++ ++C E F++ G HR TC G WT P
Sbjct: 692 GDIP-ELEHGWAQLSSPPYYYGDSVEFNCSESFTMIG---HRSITC-IHGVWTQLP 742
Score = 115 bits (288), Expect = 8e-25
Identities = 214/897 (23%), Positives = 329/897 (36%), Gaps = 173/897 (19%)
Query: 2468 CSLPRAPLHGFILGQTSTQPGGSIHFG------CNAGYRLVGHSMAICTRHPQGYHLWSE 2521
C AP +G I+ ++ +P HFG CN+GY++ G C+ G+ WS+
Sbjct: 146 CLPVTAPENGKIVS-SAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCS--DDGF--WSK 200
Query: 2522 AIPLCQALSCGLPEAPKNGMVFGK-EYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWS 2580
P C +SC P+ + K Y + Y C+ GY +A C ++G W
Sbjct: 201 EKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAV--CTESG-W- 256
Query: 2581 NRNVPPQCVPVTCP-------DVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYY-YTG 2632
P C +C D S + ++H R E YQ C G+Y T
Sbjct: 257 --RPLPSCEEKSCDNPYIPNGDYSPLRIKH---RTGDEITYQ--------CRNGFYPATR 303
Query: 2633 QRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNG-HRIGTLSVYGATAI-----FSCNS 2686
+C + G W P C + C I G + Y A+ + C+
Sbjct: 304 GNTAKCTSTG-WI---PAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDE 359
Query: 2687 GYTLVGSRVRE---CMANGLWSGSEVRCLAGHCGTPEPIVNGH--INGENYSYRGSVVYQ 2741
+ + C +G WS + V CL C P + NG+ +G + S+
Sbjct: 360 HFETPSGSYWDHIHCTQDG-WSPA-VPCLR-KCYFPY-LENGYNQNHGRKFVQGKSIDVA 415
Query: 2742 CNAGFRLIGMSVRICQQDHHWSGKTPFCVLV-SCGHPGSPPHSQMSGDS---YTVGAVVR 2797
C+ G+ L + ++ WS TP C+ V +C + +S Y + +
Sbjct: 416 CHPGYALPKAQTTVTCMENGWS-PTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAK 474
Query: 2798 YSC-IGKRTLVGNSTR--MCGLDGHWTGSLPHC--------------------------- 2827
Y C +G T G ++ CG DG W+ P C
Sbjct: 475 YQCKLGYVTADGETSGSITCGKDG-WSAQ-PTCIKSCDIPVFMNARTKNDFTWFKLNDTL 532
Query: 2828 -----------SGTSVG--VCGD----------------PGIPAHGI--RLGDSFDPGTV 2856
+G++ G VCG P I H + R D + G V
Sbjct: 533 DYECHDGYESNTGSTTGSIVCGYNGWSDLPICYERECELPKIDVHLVPDRKKDQYKVGEV 592
Query: 2857 MRFSCEAGHVLRGSSERTCQANGSWSGSQPEC--GVISCGNPGTPSNARV--VFSDGLVF 2912
++FSC+ G + G + C G S P C V SCG P N V +
Sbjct: 593 LKFSCKPGFTIVGPNSVQCYHFG-LSPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGH 651
Query: 2913 SSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLV--INCGD-PGIPANGLRLGN-DF 2968
S + Y C + G C V+G WT + P C+V CGD P + +L + +
Sbjct: 652 SEVVEYYCNPRFLMKGPNKIQC-VDGEWT-TLPVCIVEESTCGDIPELEHGWAQLSSPPY 709
Query: 2969 RYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKAL----MCKPPPLIPNGKVV 3024
Y +V + C + M HR ++C W P C A+ CK LI + +
Sbjct: 710 YYGDSVEFNCSESFTMIGHR--SITCIHG-VWT-QLPQCVAIDKLKKCKSSNLIILEEHL 765
Query: 3025 GS--DFMWGSSVTYAC--LEGYQLSLPAVFTCEGNGSWTGELPQCFPV---FCGDPGVPS 3077
+ +F S++ Y C EG+ + T NG W E+ C C P
Sbjct: 766 KNKKEFDHNSNIRYRCRGKEGW------IHTVCINGRWDPEV-NCSMAQIQLCPPPPQIP 818
Query: 3078 RGRREDRGFSYR--SSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPG 3135
+YR VS C ++ C+ DG W P C++ C+ P
Sbjct: 819 NSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCK-DGRWQSI-PLCVEK--IPCSQPP 874
Query: 3136 VPQFGIQNNS----QGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCR 3191
+ G N+S + Y G+ + + C+ G+ + TC WS +PP C C+
Sbjct: 875 QIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMG-KWS-SPPQCEGLPCK 932
Query: 3192 QPETPTHANVGAL-DLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLE 3247
P +H V + D G + Y C EGF + G + K G PP C++
Sbjct: 933 SPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPA---IAKCLGEKWSHPPSCIK 986
Score = 110 bits (276), Expect = 2e-23
Identities = 151/619 (24%), Positives = 237/619 (38%), Gaps = 81/619 (13%)
Query: 2468 CSLPRAPLHGFILGQTSTQPGGS--IHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPL 2525
C P L+G + +T + G S + + CN + + G + C W+ +P+
Sbjct: 630 CGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVDGE-----WT-TLPV 683
Query: 2526 C--QALSCG-LPEAPKN-GMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSN 2581
C + +CG +PE + Y G ++CSE + + T C+ G+W+
Sbjct: 684 CIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSIT--CIH-GVWTQ 740
Query: 2582 RNVPPQCVPVT----CPDVSSISVEHGRWRLIFETQYQFQAQLMLIC--DPGYYYTGQRV 2635
PQCV + C + I +E L + ++ + + C G+ +T
Sbjct: 741 L---PQCVAIDKLKKCKSSNLIILEE---HLKNKKEFDHNSNIRYRCRGKEGWIHT---- 790
Query: 2636 IRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVY--GATAIFSCNSGYTLVGS 2693
NG+W + +I C P PN H + T Y G C Y +
Sbjct: 791 --VCINGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEG 848
Query: 2694 RVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHING-----ENYSYRGSVVYQCNAGFRL 2748
C +G W + C P I +G IN E+Y++ + Y C GFR+
Sbjct: 849 EEITCK-DGRWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRI 907
Query: 2749 IGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMS--GDSYTVGAVVRYSCIGKRTL 2806
+ C WS P C + C P H ++ DSY G V Y C +
Sbjct: 908 SEENETTCYMGK-WSSP-PQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGI 965
Query: 2807 VGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLG---DSFDPGTVMRFSCEA 2863
G + C L W+ P C T C + I +G D + G + ++C
Sbjct: 966 DGPAIAKC-LGEKWSHP-PSCIKTD---CLSLPSFENAIPMGEKKDVYKAGEQVTYTCAT 1020
Query: 2864 GHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSS--IVYECR 2921
+ + G+S TC N W+G +P C SC NP T NA +V + S + Y+CR
Sbjct: 1021 YYKMDGASNVTC-INSRWTG-RPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCR 1078
Query: 2922 EGYYATGLLSRHCSVNGTWTGSDPECL--VINCGDPGIPANGLRLG---NDFRYNKTVTY 2976
Y G C +NG WT P+C CG P NG + + +V Y
Sbjct: 1079 SPYEMFGDEEVMC-LNGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEY 1136
Query: 2977 QCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSDFMW------ 3030
QC Y +E ++ ++C ++ W+ P C ++ N + W
Sbjct: 1137 QCQNLYQLEGNKR--ITC-RNGQWS-EPPKCLHPCVISREIMENYNIA---LRWTAKQKL 1189
Query: 3031 ----GSSVTYACLEGYQLS 3045
G SV + C GY+LS
Sbjct: 1190 YSRTGESVEFVCKRGYRLS 1208
Score = 52.4 bits (124), Expect = 8e-06
Identities = 43/199 (21%), Positives = 75/199 (37%), Gaps = 16/199 (8%)
Query: 3079 GRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQP--SCIDPTLTTCADPGV 3136
G D+ + + + C P +G+ C+ G W P C C PG
Sbjct: 35 GSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRK-GEWVALNPLRKC---QKRPCGHPGD 90
Query: 3137 PQFGIQNNSQG--YQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPE 3194
FG + G ++ G ++ C +GY L G W+ P C C
Sbjct: 91 TPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTNDIPICEVVKCLPVT 150
Query: 3195 TPTHANVGALDLPS-----MGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVR 3249
P + + + + G + + C G+ ++G E C DG W+ + P C+E+
Sbjct: 151 APENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMH-CSDDGFWSKEKPKCVEI- 208
Query: 3250 PSGRPINTAREPPLTQALI 3268
S + + P++Q +I
Sbjct: 209 -SCKSPDVINGSPISQKII 226
Score = 50.4 bits (119), Expect = 3e-05
Identities = 121/621 (19%), Positives = 210/621 (33%), Gaps = 156/621 (25%)
Query: 1054 QFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAE---CGNSVTGTQGTLL 1110
++G + + + C P + ++G +I C+ G W++ LP C+ E CG+ G
Sbjct: 648 EYGHSEVVEYYCNPRFLMKGPNKIQCVDGE---WTT-LPVCIVEESTCGDIPELEHGWAQ 703
Query: 1111 SPNFPVNYNNNHE----------------CIYSIQTQPGKGIQL-KARAFELSEGDVLKV 1153
+ P Y ++ E CI+ + TQ + + + K + + S +L+
Sbjct: 704 LSSPPYYYGDSVEFNCSESFTMIGHRSITCIHGVWTQLPQCVAIDKLKKCKSSNLIILEE 763
Query: 1154 YDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCED 1213
+ N F H+ + W+ T N E++ S ++ C
Sbjct: 764 HLKNKKE------FDHNS--NIRYRCRGKEGWIH--TVCINGRWDPEVNCSMAQIQLCPP 813
Query: 1214 PGTPKFGYKVHDEGHFA-GSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAE-- 1270
P + + ++ G VS C Y ++ EE+ C G W + +P CV +
Sbjct: 814 PPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCKDGR---W-QSIPLCVEKIP 869
Query: 1271 CG-------GTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVH 1323
C GT+ S Q Y H +T E F + + E
Sbjct: 870 CSQPPQIEHGTINSSRSSQ-------ESYAHGTKLSYTCEGG--------FRISEENETT 914
Query: 1324 DVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTAT 1383
+ W P + LP
Sbjct: 915 CYMGKWSSPPQC---------EGLP----------------------------------- 930
Query: 1384 SCNDPGIPQNG--SRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC 1441
C P +G + DS++ G+ ++C G+ + G A C+ + W PP+C
Sbjct: 931 -CKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGEK----WS-HPPSC 984
Query: 1442 IAPCGGDLTGPSGVILSPNYPEPYPPGKECD-WKVTVSPDYVIALVFNIFNLEPGYDFLH 1500
I + + P++ P G++ D +K Y A + +
Sbjct: 985 IK---------TDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTCINS 1035
Query: 1501 IYDGRDSLS-------PLIGSFY-----GSQLPG--RIESSSNSLFLAFRSDASVSNAGF 1546
+ GR + P + + Y S+ P R+ S + F + + G
Sbjct: 1036 RWTGRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLNG- 1094
Query: 1547 VIDYTENPR-----ESCFDPGSIKNGTRVGSDLKL---GSSVTYYCHGGYEVEGTSTLSC 1598
++TE P+ C P I NG L + SSV Y C Y++EG ++C
Sbjct: 1095 --NWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITC 1152
Query: 1599 ILGPDGKPVWNNPRPVCTAPC 1619
G W+ P P C PC
Sbjct: 1153 RNGQ-----WSEP-PKCLHPC 1167
Score = 48.9 bits (115), Expect = 9e-05
Identities = 137/716 (19%), Positives = 239/716 (33%), Gaps = 147/716 (20%)
Query: 1906 LSSCPEPAVPSNG---VKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPP 1962
+ SC P NG KT E Y ++VV + C P + ++G I C+ G W P
Sbjct: 627 VQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVDG---EWT-TLP 682
Query: 1963 LCIAQ---CGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNH 2019
+CI + CG E G P Y +++ F F T H
Sbjct: 683 VCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVE----------FNCSESF----TMIGH 728
Query: 2020 DYIEIRNGPYETSRMMGRFSGSELPSSL----LSTSHETTVYFHSDHSQNRPGFKLEYQD 2075
I +G + ++LP + L + + +H +N+ F
Sbjct: 729 RSITCIHGVW-----------TQLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFD----- 772
Query: 2076 LTYSHQISSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPE--PFANGI 2133
++ I RG + V + WD + C ++Q CP P P ++ +
Sbjct: 773 --HNSNIRYRCRG-------KEGWIHTVCINGRWDPEVNCSMAQIQLCPPPPQIPNSHNM 823
Query: 2134 VRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKC--EVPCGGNITSSNG 2191
Y G+ V+ C Y + +TC+ G W +P C ++PC +G
Sbjct: 824 TTTLNYRDGEKVSVLCQENYLIQEGEEITCKDG---RW-QSIPLCVEKIPCSQPPQIEHG 879
Query: 2192 TVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGV 2251
T+ S SSQ+ HG +L+ + G F
Sbjct: 880 TINSS------RSSQE-------SYAHGTKLSYTC-----EGGF---------------- 905
Query: 2252 FTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEE 2311
+ + ++ + + K+ G+ C P + + V ++
Sbjct: 906 ------RISEENETTCYMGKWSSPPQCEGL-----------PCKSPPEISHGVVAHMSDS 948
Query: 2312 FNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQ 2371
+ G+ V Y+C GF + G I C LG ++ PP + C + L + + + +
Sbjct: 949 YQYGEEVTYKCFEGFGIDGPAIAKC-LGE--KWSHPPSCIKTDCLS--LPSFENAIPMGE 1003
Query: 2372 S---YPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSP-LLKAL 2427
Y TC+ +++ N++ + + + P+ Q+ ++
Sbjct: 1004 KKDVYKAGEQVTYTCATYYKMDGASNVTCINSRWTGRPTCRDTSCVNPPTVQNAYIVSRQ 1063
Query: 2428 SGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGF-----KIRYSAPYCSLPRAPLHGFILG- 2481
Y + V S Y + + G + + S C P +G I
Sbjct: 1064 MSKYPSGERVRYQCRSPYEMFGDEEVMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSF 1123
Query: 2482 -QTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNG 2540
+ P S+ + C Y+L G+ C R+ Q WSE P C C +
Sbjct: 1124 PLSVYAPASSVEYQCQNLYQLEGNKRITC-RNGQ----WSEP-PKC-LHPCVISREIMEN 1176
Query: 2541 MVFGKEYT--------VGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQC 2588
+T G + C GY L + + L T W + P C
Sbjct: 1177 YNIALRWTAKQKLYSRTGESVEFVCKRGYRL----SSRSHTLRTTCWDGKLEYPTC 1228
Score = 41.2 bits (95), Expect = 0.018
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 1727 VPRTSATQCSSVPEPRYGKRLGS------DFSVGAIVRFECNSGYALQGSPEIECLPVPG 1780
+P +C V P GK + S ++ G VRF CNSGY ++G E+ C
Sbjct: 138 IPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHC----S 193
Query: 1781 ALAQWNVSAPTCV 1793
W+ P CV
Sbjct: 194 DDGFWSKEKPKCV 206
Score = 39.7 bits (91), Expect = 0.053
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 13/78 (16%)
Query: 2139 YNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWD--HPLPKCEV-PCG-------GNITS 2188
Y G ++C PGY+ G+ ++ C+ G W +PL KC+ PCG G T
Sbjct: 42 YPEGTQAIYKCRPGYRSLGNVIMVCRKG---EWVALNPLRKCQKRPCGHPGDTPFGTFTL 98
Query: 2189 SNGTVYSPGFPSPYSSSQ 2206
+ G V+ G + Y+ ++
Sbjct: 99 TGGNVFEYGVKAVYTCNE 116
Score = 39.7 bits (91), Expect = 0.053
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 14/77 (18%)
Query: 349 PERGKRLGS------DFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRA 402
PE GK + S ++ G +V+F CN GY ++G + + C D F WS +P C
Sbjct: 152 PENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCS--DDGF--WSKEKPKCVE 207
Query: 403 RMCDAHLRGPSGIITSP 419
C + P I SP
Sbjct: 208 ISC----KSPDVINGSP 220
Score = 38.5 bits (88), Expect = 0.12
Identities = 19/64 (29%), Positives = 38/64 (59%), Gaps = 8/64 (12%)
Query: 516 IEQGSCGDPGIP----AYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKK 571
+E+ +CGD IP + + +++GD+++F C +F ++G ++ITC + W+ +
Sbjct: 686 VEESTCGD--IPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-IHGVWT-QL 741
Query: 572 PGCV 575
P CV
Sbjct: 742 PQCV 745
Score = 38.5 bits (88), Expect = 0.12
Identities = 49/238 (20%), Positives = 80/238 (33%), Gaps = 34/238 (14%)
Query: 1558 CFDPGSIKNGTRVGS-----DLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPR 1612
C P I++GT S G+ ++Y C GG+ + + +C +G W++P
Sbjct: 870 CSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGK-----WSSPP 924
Query: 1613 PVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVV 1672
PC S GVV + +Y G+ Y F F A+ +
Sbjct: 925 QCEGLPCKSPPEISHGVV--AHMSDSYQYGE--------EVTYKCFEGFGIDGPAIAKCL 974
Query: 1673 EVHDGHSQHSRLLSSLSGSHTGESLPLATSNQV-----------LIKFSAKGLAPARGFH 1721
H LS ++P+ V + G + +
Sbjct: 975 GEKWSHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTCIN 1034
Query: 1722 FVYQAVPRTSATQCSSVPEPRYG---KRLGSDFSVGAIVRFECNSGYALQGSPEIECL 1776
+ P T C + P + R S + G VR++C S Y + G E+ CL
Sbjct: 1035 SRWTGRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCL 1092
Score = 38.1 bits (87), Expect = 0.15
Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 6/60 (10%)
Query: 867 CLDPGIPVNGQ------RHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSC 920
CL P NG+ +++ G V F C+SGY + E + C + WS+ P C
Sbjct: 146 CLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKC 205
Score = 37.4 bits (85), Expect = 0.26
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 9/68 (13%)
Query: 1207 ELIKCEDPGTPKFGYKVHD------EGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTW 1260
E++KC P+ G V E HF G +V F C+ GY + G EE+ C + W
Sbjct: 142 EVVKCLPVTAPENGKIVSSAMEPDREYHF-GQAVRFVCNSGYKIEGDEEMHC--SDDGFW 198
Query: 1261 DRPLPTCV 1268
+ P CV
Sbjct: 199 SKEKPKCV 206
Score = 37.4 bits (85), Expect = 0.26
Identities = 14/43 (32%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 537 FHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCV-FSC 578
+H G ++F C +++ G + + C + WS +KP CV SC
Sbjct: 168 YHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISC 210
Score = 37.0 bits (84), Expect = 0.34
Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 6/60 (10%)
Query: 1038 PCEEPEVPAYSIRKGLQ--FGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCV 1095
PC+ P ++ + + + G+ +T+ CF G+ ++G A CLG + WS P P C+
Sbjct: 930 PCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGEK---WSHP-PSCI 985
Score = 35.8 bits (81), Expect = 0.76
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Query: 1024 YEGFNITFSEYDLEPCEEPEVPAYSI--RKGLQFGVGDTLTFSCFPGYRLEGTARITC 1079
Y G++ Y+ E CE P++ + + RK Q+ VG+ L FSC PG+ + G + C
Sbjct: 555 YNGWSDLPICYERE-CELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQC 611
Score = 35.8 bits (81), Expect = 0.76
Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 5/63 (7%)
Query: 519 GSCGDPGIPAYGRREG---SRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCV 575
G CG P G S + +++++CQ ++L G K ITC +N QWS + P C+
Sbjct: 1107 GKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITC-RNGQWS-EPPKCL 1164
Query: 576 FSC 578
C
Sbjct: 1165 HPC 1167
Score = 35.4 bits (80), Expect = 1.00
Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 8/70 (11%)
Query: 133 VLPSHTCGNPGRLPNGIQQGST--FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWD 190
++ TCG+ L +G Q S+ + GD V ++C+ F + GH +TC G W
Sbjct: 685 IVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIHG-----VWT 739
Query: 191 FPLPSCRADD 200
LP C A D
Sbjct: 740 -QLPQCVAID 748
Score = 34.3 bits (77), Expect = 2.2
Identities = 38/171 (22%), Positives = 67/171 (39%), Gaps = 21/171 (12%)
Query: 976 DYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYD 1035
DY I G + + +R R P++ G Y ++ F + ++ + T +
Sbjct: 326 DYPDIKHGGLYHENMR-----RPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWS 380
Query: 1036 -----LEPCEEPEVP-AYSIRKGLQFGVGDTLTFSCFPGYRL-EGTARITCLGGRRRLWS 1088
L C P + Y+ G +F G ++ +C PGY L + +TC+ W
Sbjct: 381 PAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCM---ENGW- 436
Query: 1089 SPLPRC--VAECGNSVTGTQGTLLSPN---FPVNYNNNHECIYSIQTQPGK 1134
SP PRC V C S + +S + + + ++C T G+
Sbjct: 437 SPTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGE 487
Score = 33.1 bits (74), Expect = 5.0
Identities = 18/77 (23%), Positives = 29/77 (37%), Gaps = 9/77 (11%)
Query: 1372 GFAIQFSVSTATSCNDPGIPQNGSRSGDSWEA------GDSTVFQCDPGYALQGSAEISC 1425
G+ + C P+NG + E G + F C+ GY ++G E+ C
Sbjct: 133 GWTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHC 192
Query: 1426 VKIENRFFWQPSPPTCI 1442
+ FW P C+
Sbjct: 193 ---SDDGFWSKEKPKCV 206
Score = 32.3 bits (72), Expect = 8.4
Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 13/82 (15%)
Query: 2109 WDLD-PGCEAYELQECPDPEPFANGIVRGAG------YNVGQSVTFECLPGYQLTGHPVL 2161
W D P CE + PE NG + + Y+ GQ+V F C GY++ G +
Sbjct: 134 WTNDIPICEVVKCLPVTAPE---NGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEM 190
Query: 2162 TCQHGTNRNWDHPLPKC-EVPC 2182
C + W PKC E+ C
Sbjct: 191 HC--SDDGFWSKEKPKCVEISC 210
Score = 32.3 bits (72), Expect = 8.4
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 10/64 (15%)
Query: 1558 CFDPGSIKNGTRVGSDLK------LGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNP 1611
C + +NG V S ++ G +V + C+ GY++EG + C DG W+
Sbjct: 146 CLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHC--SDDG--FWSKE 201
Query: 1612 RPVC 1615
+P C
Sbjct: 202 KPKC 205
Score = 32.3 bits (72), Expect = 8.4
Identities = 11/30 (36%), Positives = 19/30 (63%)
Query: 532 REGSRFHHGDTLKFECQPAFELVGQKAITC 561
R+ ++ G+ LKF C+P F +VG ++ C
Sbjct: 582 RKKDQYKVGEVLKFSCKPGFTIVGPNSVQC 611
>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
sapiens]
Length = 730
Score = 154 bits (390), Expect = 1e-36
Identities = 96/288 (33%), Positives = 152/288 (52%), Gaps = 32/288 (11%)
Query: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLE 1851
CGG++ + G I SP +P+ Y S C+W+I V EG + + SF E++ +D LE
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 1852 VFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPE 1911
V DG + T++G + G P + STS++L+L F SD S++ AGF + + E
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF----FKEVDE 550
Query: 1912 PAVPSNGVKTGERYLVNDVVSFQC--EPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCG 1969
+ P+ G E+ +N + S++C +PGY L P R C A CG
Sbjct: 551 CSRPNRG--GCEQRCLNTLGSYKCSCDPGYELA--------PDKRR--------CEAACG 592
Query: 1970 GTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIEIR 2025
G + ++ G I SPG+P YP N +C W++ P + +QF F TE N +D++E+R
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2026 NGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEY 2073
+G S++ G+F GSE P + S + V F SD++ ++ GFK +
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 148 bits (373), Expect = 1e-34
Identities = 100/303 (33%), Positives = 139/303 (45%), Gaps = 34/303 (11%)
Query: 1269 AECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE----VHD 1324
A CGG V+ + G + SP YP Y + CIW I+ G +GL F F+ E +D
Sbjct: 433 AICGGDVKKDY-GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 1325 VLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQF--SVSTA 1382
L + DG ES L+ G P D+ ST + + L+F +D +K GFA+ F V
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 1383 TSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCI 1442
+ N G Q + S++ CDPGY L P C
Sbjct: 552 SRPNRGGCEQRCLNTLGSYKCS------CDPGYELA-----------------PDKRRCE 588
Query: 1443 APCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPG----YDF 1498
A CGG LT +G I SP +P+ YPP K C W++ Y I+L F+ F E YDF
Sbjct: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
Query: 1499 LHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESC 1558
+ + G + S L G F GS+ P I S N++ + F+SD +VS GF + R +
Sbjct: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRPAL 708
Query: 1559 FDP 1561
P
Sbjct: 709 QPP 711
Score = 135 bits (341), Expect = 5e-31
Identities = 93/307 (30%), Positives = 143/307 (46%), Gaps = 34/307 (11%)
Query: 562 QKNNQWSAKKPGCVFS--CFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLA 619
+ ++ W K V+ C + G + SPNYP+DY C+W I + L
Sbjct: 417 RSSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLT 476
Query: 620 FNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTG 675
F ++E +D+L ++DG + + ++G + G + P I S+ L+F +D S
Sbjct: 477 FQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSIN 536
Query: 676 KRGFNITFTTFRH-NECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVL 734
K GF + F F+ +EC P R G C++ L T GS +C
Sbjct: 537 KAGFAVNF--FKEVDECSRPN------RGG------------CEQRCLNTLGSYKCSC-- 574
Query: 735 KEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITF 794
+ RCEA CGG LT +G+I SPGWP Y +C W + A Y I + F
Sbjct: 575 -DPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQF 633
Query: 795 DRFKTEVN----YDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSD 850
D F+TE N YD +EVR G T + L G + G++ P+ + S N + + F +D + S
Sbjct: 634 DFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSK 693
Query: 851 IGFQLRY 857
GF+ +
Sbjct: 694 KGFKAHF 700
Score = 125 bits (315), Expect = 6e-28
Identities = 84/288 (29%), Positives = 141/288 (48%), Gaps = 29/288 (10%)
Query: 404 MCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLER----GYDT 459
+C ++ G I SPN+P Y + C+W I ++ + L F+ F++ER YD
Sbjct: 434 ICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQ-VSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 460 LTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQG 519
L V DG + T++ G PD I ST+ ++WL F +DGS + GF ++ + E
Sbjct: 493 LEVRDG--HSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVD 549
Query: 520 SCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCF 579
C P G E + + K C P +EL K C +C
Sbjct: 550 ECSRPN---RGGCEQRCLNTLGSYKCSCDPGYELAPDKR--------------RCEAACG 592
Query: 580 FNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEP----QFDFLVIK 635
T +G + SP +P++Y + +C+W ++A + RI L F+ + E ++DF+ ++
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 636 DGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITF 683
G TA++ + G F G++ P ITS + R+EF++D++ K+GF F
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 125 bits (314), Expect = 7e-28
Identities = 92/292 (31%), Positives = 137/292 (46%), Gaps = 32/292 (10%)
Query: 749 EAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN----YD 804
EA CGG + G I SP +P Y+ + C W I+ G+ + +TF F+ E + YD
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 805 TLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQS 864
LEVRDG + S+ LIG Y G + P + STS+ L+L F +D S + GF + + +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK---EV 548
Query: 865 DHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALC 924
D C P QR N L ++ C C+P ++ + CEA C
Sbjct: 549 DECSRPNRGGCEQRCLN-----TLGSYKCS------------CDPGYELAPDKRRCEAAC 591
Query: 925 GGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESG----HDYLLI 980
GGF+ +G+I SPG+P YP N NC W + + F F E +D++ +
Sbjct: 592 GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
Query: 981 TENGSFTQPLR-QLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITF 1031
+ L + GS P I++ Y N +V F SD ++S +GF F
Sbjct: 652 RSGLTADSKLHGKFCGSEKPEVITS-QYNNM--RVEFKSDNTVSKKGFKAHF 700
Score = 122 bits (306), Expect = 6e-27
Identities = 87/291 (29%), Positives = 133/291 (45%), Gaps = 32/291 (10%)
Query: 1096 AECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGD-----V 1150
A CG V G + SPN+P +Y + CI+ IQ G + L ++FE+ D
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1151 LKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIK 1210
L+V DG++ S+ L+G + E + STSS LWL F++D GF ++F E+ +
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPD-DIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
Query: 1211 CEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAE 1270
C P + + S SCDPGY L + C A
Sbjct: 551 CSRPNRGGCEQRCLN----TLGSYKCSCDPGYELAPDKR----------------RCEAA 590
Query: 1271 CGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE----VHDVL 1326
CGG + +++G + SPG+P Y N NCIW + A I L F F+TE +D +
Sbjct: 591 CGGFLT-KLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFV 649
Query: 1327 RIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQF 1377
+ G L + G P+ + S +N++ ++F +D SK+GF F
Sbjct: 650 EVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 117 bits (293), Expect = 2e-25
Identities = 85/318 (26%), Positives = 133/318 (41%), Gaps = 70/318 (22%)
Query: 1966 AQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDY 2021
A CGG V++ G I SP +P +Y + C W+I + GF + F +F E + +DY
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 2022 IEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQ 2081
+E+R+G E+S ++GR+ G E P + STS + F SD S N+ GF + +
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK------ 546
Query: 2082 ISSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNV 2141
++ E R N GCE Q C N
Sbjct: 547 --------EVDECSRPNR-------------GGCE----QRC---------------LNT 566
Query: 2142 GQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSP 2201
S C PGY+L +CE CGG +T NG++ SPG+P
Sbjct: 567 LGSYKCSCDPGYELAPDK----------------RRCEAACGGFLTKLNGSITSPGWPKE 610
Query: 2202 YSSSQDCVWLITVPIGHGVRLNLSLLQTEPSG----DFITIWDGPQQTAPRLGVFTRSMA 2257
Y +++C+W + P + + L +TE + DF+ + G + G F S
Sbjct: 611 YPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEK 670
Query: 2258 KKTVQSSSNQVLLKFHRD 2275
+ + S N + ++F D
Sbjct: 671 PEVITSQYNNMRVEFKSD 688
Score = 112 bits (281), Expect = 5e-24
Identities = 86/298 (28%), Positives = 130/298 (43%), Gaps = 37/298 (12%)
Query: 1614 VCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFH-----TAL 1668
V A CGG G + SPNYP +Y ++C++ + V + + V F F +
Sbjct: 430 VYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCA 489
Query: 1669 NDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHF-VYQAV 1727
D +EV DGHS+ S L+ G + + +TS+++ +KF + G GF ++ V
Sbjct: 490 YDYLEVRDGHSESSTLIGRYCGYEKPDDIK-STSSRLWLKFVSDGSINKAGFAVNFFKEV 548
Query: 1728 PRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNV 1787
S E R LGS + C+ GY L
Sbjct: 549 DECSRPNRGGC-EQRCLNTLGS-------YKCSCDPGYELAPDKR--------------- 585
Query: 1788 SAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN- 1846
C CGG LT+ G+I SPG+P+ Y + NC+W++V P I +Q F TE N
Sbjct: 586 ---RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGND 642
Query: 1847 ---WDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEY 1901
+D +EV G + G F G+ P ++ S N + + F SD +VS GF +
Sbjct: 643 VCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 111 bits (278), Expect = 1e-23
Identities = 88/290 (30%), Positives = 128/290 (44%), Gaps = 36/290 (12%)
Query: 35 GTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEED----FDVLSVFDGPPQPE 90
G ++SP +P Y C W I E + L FQSF +E +D L V DG +
Sbjct: 444 GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESS 503
Query: 91 NLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRLPNGIQ 150
L R G++ P I S ++ L L+ +SD +++ GF + C P R G +
Sbjct: 504 TLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF-FKEVDECSRPNR--GGCE 560
Query: 151 QGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQS 210
Q LG Y C+ C G E + R + ACGG L +
Sbjct: 561 QRCLNTLGS---YKCS------------CDPGYELAPD------KRRCEAACGGFLTKLN 599
Query: 211 GIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG----YDFLEVTG--TEGS 264
G I+SP +P EY N +C W ++A I+L F F+ E YDF+EV T S
Sbjct: 600 GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADS 659
Query: 265 SLW--FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELK 312
L F G+ P + S N +R+ F SD ++GF A + +K+ L+
Sbjct: 660 KLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRPALQ 709
Score = 108 bits (270), Expect = 9e-23
Identities = 123/485 (25%), Positives = 190/485 (39%), Gaps = 100/485 (20%)
Query: 734 LKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKIT 793
L +G + + +C A CG L +G SP +P Y + C W I PG I +
Sbjct: 305 LSKGDIAQARKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILN 363
Query: 794 F---DRFKTEVN-YDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHS 849
F D +++ + YD +EVRDG APL G + G+++P+ ++ST + L++ F + +
Sbjct: 364 FTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
Query: 850 DIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEP 909
GF YE I G D D G+ S P + P
Sbjct: 424 GKGFFAVYEAIC------------------GGD--------VKKDYGHIQSPNYPDDYRP 457
Query: 910 NFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTF 969
+ +C IQ S G + F F
Sbjct: 458 S-----------KVCIWRIQVSEGFHVGLTFQSFEIER---------------------- 484
Query: 970 HLESGHDYLLITENGSFTQPL-RQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFN 1028
H +DYL + + S + L + G P I + + ++F+SD S++ GF
Sbjct: 485 HDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKS---TSSRLWLKFVSDGSINKAGFA 541
Query: 1029 ITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTL---TFSCFPGYRLEGTARITCLGGRRR 1085
+ F + +++ C P R G + +TL SC PGY L R
Sbjct: 542 VNFFK-EVDECSRPN------RGGCEQRCLNTLGSYKCSCDPGYELAPDKR--------- 585
Query: 1086 LWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFEL 1145
RC A CG +T G++ SP +P Y N CI+ + I L+ FE
Sbjct: 586 -------RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFET 638
Query: 1146 SEGDVLK-----VYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFE 1200
DV K V G ++L G F SE V + S +++ ++F +D + KGF+
Sbjct: 639 EGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFK 697
Query: 1201 LHFSS 1205
HF S
Sbjct: 698 AHFFS 702
Score = 94.0 bits (232), Expect = 2e-18
Identities = 79/310 (25%), Positives = 129/310 (41%), Gaps = 37/310 (11%)
Query: 2179 EVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SGD 2234
E CGG++ G + SP +P Y S+ C+W I V G V L + E + D
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 2235 FITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGI-FAIAFSAYPLTK 2293
++ + DG +++ +G + ++S+S+++ LKF D + FA+ F + +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
Query: 2294 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEV 2353
C P E N + C PG+ L ++ CE
Sbjct: 551 CSRPN-----RGGCEQRCLNTLGSYKCSCDPGYELAPDK----------------RRCEA 589
Query: 2354 HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEK----QYD 2409
C LT G I S +P YP + C W + Y ISL ++F +E +YD
Sbjct: 590 AC--GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 2410 EFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRY---SAP 2466
E+ G + S L G+ P ++TS N++ + + SD+ ++KGFK + P
Sbjct: 648 FVEVRSGLTADSKLHGKFCGS-EKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRP 706
Query: 2467 YCSLPRAPLH 2476
PR H
Sbjct: 707 ALQPPRGRPH 716
Score = 92.8 bits (229), Expect = 5e-18
Identities = 125/503 (24%), Positives = 189/503 (37%), Gaps = 139/503 (27%)
Query: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG 85
C L G SP +P GY + +C W I+ +I L F S L
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDL------------ 369
Query: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRL 145
R+RL + DY GF L CG+ +L
Sbjct: 370 ------YRSRLCWY-------------------DYVEVRDGFWRKAP-LRGRFCGS--KL 401
Query: 146 PNGIQQGSTFNLGDKVRYSCNL---GFFLEGHAVLTCHAGSENSATWDFPLPSCRADDAC 202
P I + L + R S N GFF A+ C
Sbjct: 402 PEPIVSTDS-RLWVEFRSSSNWVGKGFFAVYEAI-------------------------C 435
Query: 203 GGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLED----GYDFLEV 258
GG ++ G I SP++P +Y + C W I G + L F F++E YD+LEV
Sbjct: 436 GGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEV 495
Query: 259 TG--TEGSSL--WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSR 314
+E S+L + G P + S+ + L L F SDG+ + GF+ + K+++ SR
Sbjct: 496 RDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVDECSR 553
Query: 315 GVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYD 374
P++ ++ + T LG S + +C+ GY+
Sbjct: 554 -----PNRGGCEQRCLNT----------------------LG-------SYKCSCDPGYE 579
Query: 375 LQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWI 434
L KR C A C L +G ITSP +P +Y N +C+W
Sbjct: 580 LAPDKR------------------RCEA-ACGGFLTKLNGSITSPGWPKEYPPNKNCIWQ 620
Query: 435 ITALNPSKVIKLAFEEFDLERG----YDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVST 490
+ A + I L F+ F+ E YD + V G D K + G+ P++I S
Sbjct: 621 LVAPTQYR-ISLQFDFFETEGNDVCKYDFVEV-RSGLTADSK-LHGKFCGSEKPEVITSQ 677
Query: 491 NHQMWLLFQTDGSGSSLGFKASY 513
+ M + F++D + S GFKA +
Sbjct: 678 YNNMRVEFKSDNTVSKKGFKAHF 700
Score = 70.1 bits (170), Expect = 4e-11
Identities = 47/157 (29%), Positives = 74/157 (47%), Gaps = 7/157 (4%)
Query: 529 YGRREGSRFHHGDTL--KFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPS 586
Y R SR DT+ K+E +GQ+ K + A+K +C +
Sbjct: 272 YARNTFSRGIFLDTIVPKYEVNGVKPPIGQRT-RLSKGDIAQARKLYKCPACGETLQDST 330
Query: 587 GVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQ----FDFLVIKDGATAEA 642
G SP YP Y H+HCVW I P +I L F +D+ +D++ ++DG +A
Sbjct: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390
Query: 643 PVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGF 679
P+ G F G++LP I S+ +EF++ + +GF
Sbjct: 391 PLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGF 427
Score = 66.6 bits (161), Expect = 4e-10
Identities = 34/111 (30%), Positives = 58/111 (52%), Gaps = 4/111 (3%)
Query: 1968 CGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIE 2023
CG T+++ G SP +P Y ++M C W+I++ G + F + + +DY+E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 2024 IRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ 2074
+R+G + + + GRF GS+LP ++ST V F S + GF Y+
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE 432
Score = 65.1 bits (157), Expect = 1e-09
Identities = 38/110 (34%), Positives = 55/110 (50%), Gaps = 4/110 (3%)
Query: 1445 CGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPG----YDFLH 1500
CG L +G SP YP Y C W+++V+P I L F +L YD++
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1501 IYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDY 1550
+ DG +PL G F GS+LP I S+ + L++ FRS ++ GF Y
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431
Score = 61.2 bits (147), Expect = 2e-08
Identities = 38/116 (32%), Positives = 54/116 (46%), Gaps = 16/116 (13%)
Query: 201 ACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG----YDFL 256
ACG TL+ +G SSP +P+ Y + C W I G+ I L F L YD++
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 257 EVTGTEGSSLW--------FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQ 304
EV W F G+ LP P++S+ + L + F S N +GF A Y+
Sbjct: 381 EVR----DGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE 432
Score = 59.3 bits (142), Expect = 6e-08
Identities = 43/145 (29%), Positives = 68/145 (46%), Gaps = 11/145 (7%)
Query: 397 RPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERG 456
R + + C L+ +G +SP +P Y + HCVW I ++ P + I L F DL R
Sbjct: 314 RKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRI-SVTPGEKIILNFTSLDLYRS 372
Query: 457 ----YDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKAS 512
YD + V DG + + G+ +P+ IVST+ ++W+ F++ + GF A
Sbjct: 373 RLCWYDYVEVRDG--FWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Query: 513 YEEIEQGSCGDPGIPAYGRREGSRF 537
YE I CG YG + +
Sbjct: 431 YEAI----CGGDVKKDYGHIQSPNY 451
Score = 57.0 bits (136), Expect = 3e-07
Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 4/113 (3%)
Query: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLE 1851
CG L + G SP +P Y ++CVW+I V G I + S ++ +D +E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1852 VFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 1904
V DG + G F G+ +P + ST ++L++ F S + GF Y+ +
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 53.1 bits (126), Expect = 5e-06
Identities = 38/124 (30%), Positives = 61/124 (49%), Gaps = 10/124 (8%)
Query: 1091 LPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEG-- 1148
L +C A CG ++ + G SP +P Y+ + C++ I PG+ I L + +L
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 1149 ---DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSS 1205
D ++V DG A L G F S+ + + ST S LW++F + + KGF F+
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSK-LPEPIVSTDSRLWVEFRSSSNWVGKGF---FAV 430
Query: 1206 FELI 1209
+E I
Sbjct: 431 YEAI 434
Score = 52.8 bits (125), Expect = 6e-06
Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 7/116 (6%)
Query: 2175 LPKCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSG- 2233
L KC CG + S G SP +P+ YS+ CVW I+V G + LN + L S
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 2234 ---DFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDA--ATGGIFAI 2284
D++ + DG + AP G F S + + S+ +++ ++F + G FA+
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 45.4 bits (106), Expect = 0.001
Identities = 35/116 (30%), Positives = 52/116 (44%), Gaps = 6/116 (5%)
Query: 2355 CPT-NELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISL---TVEYFLSEK-QYD 2409
CP E L DSTG S YP Y C W + V P I L +++ + S YD
Sbjct: 319 CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYD 378
Query: 2410 EFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465
E+ DG ++PL G+ P + S+ + +++ + S + KGF Y A
Sbjct: 379 YVEVRDGFWRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Score = 44.7 bits (104), Expect = 0.002
Identities = 39/143 (27%), Positives = 64/143 (44%), Gaps = 7/143 (4%)
Query: 1262 RPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE 1321
R L C A CG T++ + +G SP YP Y +++C+W I G I L+F D
Sbjct: 314 RKLYKCPA-CGETLQ-DSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYR 371
Query: 1322 V----HDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQF-STDFFTSKQGFAIQ 1376
+D + + DG L G LP+ + ST + + ++F S+ + K FA+
Sbjct: 372 SRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431
Query: 1377 FSVSTATSCNDPGIPQNGSRSGD 1399
++ D G Q+ + D
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDD 454
Score = 44.3 bits (103), Expect = 0.002
Identities = 31/114 (27%), Positives = 56/114 (49%), Gaps = 6/114 (5%)
Query: 1619 CGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTV-PKDYVV--FGQFAFFHTAL--NDVVE 1673
CG S G SP YP Y++ C++ ++V P + ++ F + + L D VE
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1674 VHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAV 1727
V DG + + L GS E + ++T +++ ++F + +GF VY+A+
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPI-VSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
sapiens]
Length = 823
Score = 154 bits (390), Expect = 1e-36
Identities = 96/288 (33%), Positives = 152/288 (52%), Gaps = 32/288 (11%)
Query: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLE 1851
CGG++ + G I SP +P+ Y S C+W+I V EG + + SF E++ +D LE
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 1852 VFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPE 1911
V DG + T++G + G P + STS++L+L F SD S++ AGF + + E
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF----FKEVDE 550
Query: 1912 PAVPSNGVKTGERYLVNDVVSFQC--EPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCG 1969
+ P+ G E+ +N + S++C +PGY L P R C A CG
Sbjct: 551 CSRPNRG--GCEQRCLNTLGSYKCSCDPGYELA--------PDKRR--------CEAACG 592
Query: 1970 GTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIEIR 2025
G + ++ G I SPG+P YP N +C W++ P + +QF F TE N +D++E+R
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2026 NGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEY 2073
+G S++ G+F GSE P + S + V F SD++ ++ GFK +
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 147 bits (370), Expect = 2e-34
Identities = 98/288 (34%), Positives = 135/288 (46%), Gaps = 34/288 (11%)
Query: 1269 AECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE----VHD 1324
A CGG V+ + G + SP YP Y + CIW I+ G +GL F F+ E +D
Sbjct: 433 AICGGDVKKDY-GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 1325 VLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQF--SVSTA 1382
L + DG ES L+ G P D+ ST + + L+F +D +K GFA+ F V
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 1383 TSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCI 1442
+ N G Q + S++ CDPGY L P C
Sbjct: 552 SRPNRGGCEQRCLNTLGSYKCS------CDPGYELA-----------------PDKRRCE 588
Query: 1443 APCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPG----YDF 1498
A CGG LT +G I SP +P+ YPP K C W++ Y I+L F+ F E YDF
Sbjct: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
Query: 1499 LHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGF 1546
+ + G + S L G F GS+ P I S N++ + F+SD +VS GF
Sbjct: 649 VEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGF 696
Score = 138 bits (348), Expect = 8e-32
Identities = 95/294 (32%), Positives = 140/294 (47%), Gaps = 40/294 (13%)
Query: 1443 APCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP----GYDF 1498
A CGGD+ G I SPNYP+ Y P K C W++ VS + + L F F +E YD+
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1499 LHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESC 1558
L + DG S LIG + G + P I+S+S+ L+L F SD S++ AGF +++ + E C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE-C 551
Query: 1559 FDPGSIKNGTRVGSDLKLGSSVTYY---CHGGYEVEGTSTLSCILGPDGKPVWNNPRPVC 1615
P R G + + +++ Y C GYE L PD + C
Sbjct: 552 SRP------NRGGCEQRCLNTLGSYKCSCDPGYE----------LAPDKRR--------C 587
Query: 1616 TAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDV---- 1671
A CGG +G + SP +P+ Y + C++ + P Y + QF FF T NDV
Sbjct: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 1672 -VEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGF--HF 1722
VEV G + S+L GS E + + N + ++F + +GF HF
Sbjct: 648 FVEVRSGLTADSKLHGKFCGSEKPEVI-TSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 136 bits (342), Expect = 4e-31
Identities = 93/310 (30%), Positives = 145/310 (46%), Gaps = 34/310 (10%)
Query: 562 QKNNQWSAKKPGCVFS--CFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLA 619
+ ++ W K V+ C + G + SPNYP+DY C+W I + L
Sbjct: 417 RSSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLT 476
Query: 620 FNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTG 675
F ++E +D+L ++DG + + ++G + G + P I S+ L+F +D S
Sbjct: 477 FQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSIN 536
Query: 676 KRGFNITFTTFRH-NECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVL 734
K GF + F F+ +EC P R G C++ L T GS +C
Sbjct: 537 KAGFAVNF--FKEVDECSRPN------RGG------------CEQRCLNTLGSYKCSC-- 574
Query: 735 KEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITF 794
+ RCEA CGG LT +G+I SPGWP Y +C W + A Y I + F
Sbjct: 575 -DPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQF 633
Query: 795 DRFKTEVN----YDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSD 850
D F+TE N YD +EVR G T + L G + G++ P+ + S N + + F +D + S
Sbjct: 634 DFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSK 693
Query: 851 IGFQLRYETI 860
GF+ + ++
Sbjct: 694 KGFKAHFFSV 703
Score = 125 bits (315), Expect = 6e-28
Identities = 84/288 (29%), Positives = 141/288 (48%), Gaps = 29/288 (10%)
Query: 404 MCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLER----GYDT 459
+C ++ G I SPN+P Y + C+W I ++ + L F+ F++ER YD
Sbjct: 434 ICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQ-VSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 460 LTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQG 519
L V DG + T++ G PD I ST+ ++WL F +DGS + GF ++ + E
Sbjct: 493 LEVRDG--HSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVD 549
Query: 520 SCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCF 579
C P G E + + K C P +EL K C +C
Sbjct: 550 ECSRPN---RGGCEQRCLNTLGSYKCSCDPGYELAPDKR--------------RCEAACG 592
Query: 580 FNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEP----QFDFLVIK 635
T +G + SP +P++Y + +C+W ++A + RI L F+ + E ++DF+ ++
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 636 DGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITF 683
G TA++ + G F G++ P ITS + R+EF++D++ K+GF F
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 125 bits (314), Expect = 7e-28
Identities = 92/292 (31%), Positives = 137/292 (46%), Gaps = 32/292 (10%)
Query: 749 EAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN----YD 804
EA CGG + G I SP +P Y+ + C W I+ G+ + +TF F+ E + YD
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 805 TLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQS 864
LEVRDG + S+ LIG Y G + P + STS+ L+L F +D S + GF + + +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK---EV 548
Query: 865 DHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALC 924
D C P QR N L ++ C C+P ++ + CEA C
Sbjct: 549 DECSRPNRGGCEQRCLN-----TLGSYKCS------------CDPGYELAPDKRRCEAAC 591
Query: 925 GGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESG----HDYLLI 980
GGF+ +G+I SPG+P YP N NC W + + F F E +D++ +
Sbjct: 592 GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
Query: 981 TENGSFTQPLR-QLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITF 1031
+ L + GS P I++ Y N +V F SD ++S +GF F
Sbjct: 652 RSGLTADSKLHGKFCGSEKPEVITS-QYNNM--RVEFKSDNTVSKKGFKAHF 700
Score = 122 bits (306), Expect = 6e-27
Identities = 87/291 (29%), Positives = 133/291 (45%), Gaps = 32/291 (10%)
Query: 1096 AECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGD-----V 1150
A CG V G + SPN+P +Y + CI+ IQ G + L ++FE+ D
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1151 LKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIK 1210
L+V DG++ S+ L+G + E + STSS LWL F++D GF ++F E+ +
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPD-DIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
Query: 1211 CEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAE 1270
C P + + S SCDPGY L + C A
Sbjct: 551 CSRPNRGGCEQRCLN----TLGSYKCSCDPGYELAPDKR----------------RCEAA 590
Query: 1271 CGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE----VHDVL 1326
CGG + +++G + SPG+P Y N NCIW + A I L F F+TE +D +
Sbjct: 591 CGGFLT-KLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFV 649
Query: 1327 RIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQF 1377
+ G L + G P+ + S +N++ ++F +D SK+GF F
Sbjct: 650 EVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 117 bits (293), Expect = 2e-25
Identities = 85/318 (26%), Positives = 133/318 (41%), Gaps = 70/318 (22%)
Query: 1966 AQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDY 2021
A CGG V++ G I SP +P +Y + C W+I + GF + F +F E + +DY
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 2022 IEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQ 2081
+E+R+G E+S ++GR+ G E P + STS + F SD S N+ GF + +
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK------ 546
Query: 2082 ISSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNV 2141
++ E R N GCE Q C N
Sbjct: 547 --------EVDECSRPNR-------------GGCE----QRC---------------LNT 566
Query: 2142 GQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSP 2201
S C PGY+L +CE CGG +T NG++ SPG+P
Sbjct: 567 LGSYKCSCDPGYELAPDK----------------RRCEAACGGFLTKLNGSITSPGWPKE 610
Query: 2202 YSSSQDCVWLITVPIGHGVRLNLSLLQTEPSG----DFITIWDGPQQTAPRLGVFTRSMA 2257
Y +++C+W + P + + L +TE + DF+ + G + G F S
Sbjct: 611 YPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEK 670
Query: 2258 KKTVQSSSNQVLLKFHRD 2275
+ + S N + ++F D
Sbjct: 671 PEVITSQYNNMRVEFKSD 688
Score = 113 bits (283), Expect = 3e-24
Identities = 87/301 (28%), Positives = 132/301 (43%), Gaps = 37/301 (12%)
Query: 1614 VCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFH-----TAL 1668
V A CGG G + SPNYP +Y ++C++ + V + + V F F +
Sbjct: 430 VYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCA 489
Query: 1669 NDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHF-VYQAV 1727
D +EV DGHS+ S L+ G + + +TS+++ +KF + G GF ++ V
Sbjct: 490 YDYLEVRDGHSESSTLIGRYCGYEKPDDIK-STSSRLWLKFVSDGSINKAGFAVNFFKEV 548
Query: 1728 PRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNV 1787
S E R LGS + C+ GY L
Sbjct: 549 DECSRPNRGGC-EQRCLNTLGS-------YKCSCDPGYELAPDKR--------------- 585
Query: 1788 SAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN- 1846
C CGG LT+ G+I SPG+P+ Y + NC+W++V P I +Q F TE N
Sbjct: 586 ---RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGND 642
Query: 1847 ---WDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 1903
+D +EV G + G F G+ P ++ S N + + F SD +VS GF + +
Sbjct: 643 VCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
Query: 1904 V 1904
V
Sbjct: 703 V 703
Score = 110 bits (275), Expect = 2e-23
Identities = 86/281 (30%), Positives = 123/281 (43%), Gaps = 36/281 (12%)
Query: 35 GTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEED----FDVLSVFDGPPQPE 90
G ++SP +P Y C W I E + L FQSF +E +D L V DG +
Sbjct: 444 GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESS 503
Query: 91 NLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRLPNGIQ 150
L R G++ P I S ++ L L+ +SD +++ GF + C P R G +
Sbjct: 504 TLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF-FKEVDECSRPNR--GGCE 560
Query: 151 QGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQS 210
Q LG Y C+ C G E + R + ACGG L +
Sbjct: 561 QRCLNTLGS---YKCS------------CDPGYELAPD------KRRCEAACGGFLTKLN 599
Query: 211 GIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG----YDFLEVTG--TEGS 264
G I+SP +P EY N +C W ++A I+L F F+ E YDF+EV T S
Sbjct: 600 GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADS 659
Query: 265 SLW--FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQY 303
L F G+ P + S N +R+ F SD ++GF A +
Sbjct: 660 KLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 108 bits (270), Expect = 9e-23
Identities = 123/485 (25%), Positives = 190/485 (39%), Gaps = 100/485 (20%)
Query: 734 LKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKIT 793
L +G + + +C A CG L +G SP +P Y + C W I PG I +
Sbjct: 305 LSKGDIAQARKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILN 363
Query: 794 F---DRFKTEVN-YDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHS 849
F D +++ + YD +EVRDG APL G + G+++P+ ++ST + L++ F + +
Sbjct: 364 FTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV 423
Query: 850 DIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEP 909
GF YE I G D D G+ S P + P
Sbjct: 424 GKGFFAVYEAIC------------------GGD--------VKKDYGHIQSPNYPDDYRP 457
Query: 910 NFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTF 969
+ +C IQ S G + F F
Sbjct: 458 S-----------KVCIWRIQVSEGFHVGLTFQSFEIER---------------------- 484
Query: 970 HLESGHDYLLITENGSFTQPL-RQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFN 1028
H +DYL + + S + L + G P I + + ++F+SD S++ GF
Sbjct: 485 HDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKS---TSSRLWLKFVSDGSINKAGFA 541
Query: 1029 ITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTL---TFSCFPGYRLEGTARITCLGGRRR 1085
+ F + +++ C P R G + +TL SC PGY L R
Sbjct: 542 VNFFK-EVDECSRPN------RGGCEQRCLNTLGSYKCSCDPGYELAPDKR--------- 585
Query: 1086 LWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFEL 1145
RC A CG +T G++ SP +P Y N CI+ + I L+ FE
Sbjct: 586 -------RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFET 638
Query: 1146 SEGDVLK-----VYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFE 1200
DV K V G ++L G F SE V + S +++ ++F +D + KGF+
Sbjct: 639 EGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFK 697
Query: 1201 LHFSS 1205
HF S
Sbjct: 698 AHFFS 702
Score = 95.1 bits (235), Expect = 1e-18
Identities = 126/510 (24%), Positives = 193/510 (37%), Gaps = 139/510 (27%)
Query: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG 85
C L G SP +P GY + +C W I+ +I L F S L
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDL------------ 369
Query: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRL 145
R+RL + DY GF L CG+ +L
Sbjct: 370 ------YRSRLCWY-------------------DYVEVRDGFWRKAP-LRGRFCGS--KL 401
Query: 146 PNGIQQGSTFNLGDKVRYSCNL---GFFLEGHAVLTCHAGSENSATWDFPLPSCRADDAC 202
P I + L + R S N GFF A+ C
Sbjct: 402 PEPIVSTDS-RLWVEFRSSSNWVGKGFFAVYEAI-------------------------C 435
Query: 203 GGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLED----GYDFLEV 258
GG ++ G I SP++P +Y + C W I G + L F F++E YD+LEV
Sbjct: 436 GGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEV 495
Query: 259 TG--TEGSSL--WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSR 314
+E S+L + G P + S+ + L L F SDG+ + GF+ + K+++ SR
Sbjct: 496 RDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVDECSR 553
Query: 315 GVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYD 374
P++ ++ + T LG S + +C+ GY+
Sbjct: 554 -----PNRGGCEQRCLNT----------------------LG-------SYKCSCDPGYE 579
Query: 375 LQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWI 434
L KR C A C L +G ITSP +P +Y N +C+W
Sbjct: 580 LAPDKR------------------RCEA-ACGGFLTKLNGSITSPGWPKEYPPNKNCIWQ 620
Query: 435 ITALNPSKVIKLAFEEFDLERG----YDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVST 490
+ A + I L F+ F+ E YD + V G D K + G+ P++I S
Sbjct: 621 LVAPTQYR-ISLQFDFFETEGNDVCKYDFVEV-RSGLTADSK-LHGKFCGSEKPEVITSQ 677
Query: 491 NHQMWLLFQTDGSGSSLGFKASYEEIEQGS 520
+ M + F++D + S GFKA + + +G+
Sbjct: 678 YNNMRVEFKSDNTVSKKGFKAHFFSVLEGA 707
Score = 93.6 bits (231), Expect = 3e-18
Identities = 75/294 (25%), Positives = 125/294 (42%), Gaps = 34/294 (11%)
Query: 2179 EVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SGD 2234
E CGG++ G + SP +P Y S+ C+W I V G V L + E + D
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 2235 FITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGI-FAIAFSAYPLTK 2293
++ + DG +++ +G + ++S+S+++ LKF D + FA+ F + +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
Query: 2294 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEV 2353
C P E N + C PG+ L ++ CE
Sbjct: 551 CSRPN-----RGGCEQRCLNTLGSYKCSCDPGYELAPDK----------------RRCEA 589
Query: 2354 HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEK----QYD 2409
C LT G I S +P YP + C W + Y ISL ++F +E +YD
Sbjct: 590 AC--GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 2410 EFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRY 2463
E+ G + S L G+ P ++TS N++ + + SD+ ++KGFK +
Sbjct: 648 FVEVRSGLTADSKLHGKFCGS-EKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 70.1 bits (170), Expect = 4e-11
Identities = 47/157 (29%), Positives = 74/157 (47%), Gaps = 7/157 (4%)
Query: 529 YGRREGSRFHHGDTL--KFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPS 586
Y R SR DT+ K+E +GQ+ K + A+K +C +
Sbjct: 272 YARNTFSRGIFLDTIVPKYEVNGVKPPIGQRT-RLSKGDIAQARKLYKCPACGETLQDST 330
Query: 587 GVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQ----FDFLVIKDGATAEA 642
G SP YP Y H+HCVW I P +I L F +D+ +D++ ++DG +A
Sbjct: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390
Query: 643 PVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGF 679
P+ G F G++LP I S+ +EF++ + +GF
Sbjct: 391 PLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGF 427
Score = 66.6 bits (161), Expect = 4e-10
Identities = 34/111 (30%), Positives = 58/111 (52%), Gaps = 4/111 (3%)
Query: 1968 CGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIE 2023
CG T+++ G SP +P Y ++M C W+I++ G + F + + +DY+E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 2024 IRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ 2074
+R+G + + + GRF GS+LP ++ST V F S + GF Y+
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE 432
Score = 65.1 bits (157), Expect = 1e-09
Identities = 38/110 (34%), Positives = 55/110 (50%), Gaps = 4/110 (3%)
Query: 1445 CGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPG----YDFLH 1500
CG L +G SP YP Y C W+++V+P I L F +L YD++
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1501 IYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDY 1550
+ DG +PL G F GS+LP I S+ + L++ FRS ++ GF Y
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431
Score = 61.2 bits (147), Expect = 2e-08
Identities = 38/116 (32%), Positives = 54/116 (46%), Gaps = 16/116 (13%)
Query: 201 ACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG----YDFL 256
ACG TL+ +G SSP +P+ Y + C W I G+ I L F L YD++
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 257 EVTGTEGSSLW--------FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQ 304
EV W F G+ LP P++S+ + L + F S N +GF A Y+
Sbjct: 381 EVR----DGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE 432
Score = 59.3 bits (142), Expect = 6e-08
Identities = 43/145 (29%), Positives = 68/145 (46%), Gaps = 11/145 (7%)
Query: 397 RPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERG 456
R + + C L+ +G +SP +P Y + HCVW I ++ P + I L F DL R
Sbjct: 314 RKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRI-SVTPGEKIILNFTSLDLYRS 372
Query: 457 ----YDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKAS 512
YD + V DG + + G+ +P+ IVST+ ++W+ F++ + GF A
Sbjct: 373 RLCWYDYVEVRDG--FWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Query: 513 YEEIEQGSCGDPGIPAYGRREGSRF 537
YE I CG YG + +
Sbjct: 431 YEAI----CGGDVKKDYGHIQSPNY 451
Score = 57.0 bits (136), Expect = 3e-07
Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 4/113 (3%)
Query: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLE 1851
CG L + G SP +P Y ++CVW+I V G I + S ++ +D +E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1852 VFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 1904
V DG + G F G+ +P + ST ++L++ F S + GF Y+ +
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 53.1 bits (126), Expect = 5e-06
Identities = 38/124 (30%), Positives = 61/124 (49%), Gaps = 10/124 (8%)
Query: 1091 LPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEG-- 1148
L +C A CG ++ + G SP +P Y+ + C++ I PG+ I L + +L
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 1149 ---DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSS 1205
D ++V DG A L G F S+ + + ST S LW++F + + KGF F+
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSK-LPEPIVSTDSRLWVEFRSSSNWVGKGF---FAV 430
Query: 1206 FELI 1209
+E I
Sbjct: 431 YEAI 434
Score = 52.8 bits (125), Expect = 6e-06
Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 7/116 (6%)
Query: 2175 LPKCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSG- 2233
L KC CG + S G SP +P+ YS+ CVW I+V G + LN + L S
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 2234 ---DFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDA--ATGGIFAI 2284
D++ + DG + AP G F S + + S+ +++ ++F + G FA+
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 45.4 bits (106), Expect = 0.001
Identities = 35/116 (30%), Positives = 52/116 (44%), Gaps = 6/116 (5%)
Query: 2355 CPT-NELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISL---TVEYFLSEK-QYD 2409
CP E L DSTG S YP Y C W + V P I L +++ + S YD
Sbjct: 319 CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYD 378
Query: 2410 EFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465
E+ DG ++PL G+ P + S+ + +++ + S + KGF Y A
Sbjct: 379 YVEVRDGFWRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
Score = 44.7 bits (104), Expect = 0.002
Identities = 39/143 (27%), Positives = 64/143 (44%), Gaps = 7/143 (4%)
Query: 1262 RPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE 1321
R L C A CG T++ + +G SP YP Y +++C+W I G I L+F D
Sbjct: 314 RKLYKCPA-CGETLQ-DSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYR 371
Query: 1322 V----HDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQF-STDFFTSKQGFAIQ 1376
+D + + DG L G LP+ + ST + + ++F S+ + K FA+
Sbjct: 372 SRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431
Query: 1377 FSVSTATSCNDPGIPQNGSRSGD 1399
++ D G Q+ + D
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDD 454
Score = 44.3 bits (103), Expect = 0.002
Identities = 31/114 (27%), Positives = 56/114 (49%), Gaps = 6/114 (5%)
Query: 1619 CGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTV-PKDYVV--FGQFAFFHTAL--NDVVE 1673
CG S G SP YP Y++ C++ ++V P + ++ F + + L D VE
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1674 VHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAV 1727
V DG + + L GS E + ++T +++ ++F + +GF VY+A+
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPI-VSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
>gi|4502503 complement component 4 binding protein, alpha chain
precursor [Homo sapiens]
Length = 597
Score = 151 bits (382), Expect = 1e-35
Identities = 122/517 (23%), Positives = 208/517 (40%), Gaps = 54/517 (10%)
Query: 2714 GHCGTPEPI-----VNGHINGENYSYRGSVVYQCNAGF-RLIGMSVRICQQDHHWSGKTP 2767
G+CG P + ++ + + ++ Y C G+ R C D W T
Sbjct: 48 GNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNT- 106
Query: 2768 FCVLVSCGHPGSPPHSQMS-GDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGH---WTGS 2823
FC+ C HPG + Q+ + G+ + +SC L+G++T C + W+
Sbjct: 107 FCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHP 166
Query: 2824 LPHCSGTSVGVCGDPGIPAHGIRLGDS--FDPGTVMRFSCEAGHVLRGSSERTCQAN--- 2878
LP C + C P +G G+ + G + +SC+ L G + +C
Sbjct: 167 LPQCE---IVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENET 223
Query: 2879 -GSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFS--SSIVYECREGYYATGLLSRHCS 2935
G W S P C I+C P S+ +V G +++ +IV++C++G+ G HC
Sbjct: 224 IGVWRPSPPTCEKITCRKPDV-SHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCD 282
Query: 2936 VNGTWTGSDPECLVINCGD-PGIPANGLRL------GNDFRYNKTVTYQCVPGYMMESHR 2988
+ W S P C +C + P IP + + + Y+C PGY +
Sbjct: 283 ADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDE 342
Query: 2989 VSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSD---------FMWGSSVTYACL 3039
+ + C K+ W + C+AL C P P + NG++ + +G ++++C
Sbjct: 343 PTTVICQKNLRWTPYQG-CEALCC-PEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCH 400
Query: 3040 EGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGRREDRGFSY-RSSVSFSCHP 3098
E + S C+G+G+W+ P C + P + ++ +S+ + + + C
Sbjct: 401 ETSRFSA----ICQGDGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDK 456
Query: 3099 PLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQGYQVGSTVLFRC 3158
+LVG + C S WS P C C P + + + Y V +C
Sbjct: 457 GYILVGQAKLSC-SYSHWSAPAPQC----KALCRKPELVNGRLSVDKDQYVEPENVTIQC 511
Query: 3159 QKGYLLQGSTTRTCLPNLTWSGTPPDC---VPHHCRQ 3192
GY + G + TC N TW P C P C Q
Sbjct: 512 DSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCEQ 548
Score = 151 bits (382), Expect = 1e-35
Identities = 136/490 (27%), Positives = 195/490 (39%), Gaps = 54/490 (11%)
Query: 2611 ETQYQFQAQLMLICDPGYYYT-GQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGH- 2668
ET+++ L C PGY + + + C ++G+W R GEL NG
Sbjct: 68 ETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELR---NGQV 124
Query: 2669 RIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGL---WSGSEVRCLAGHCGTPEPIVNG 2725
I T +G+ FSC+ G+ L+GS C WS +C C P I NG
Sbjct: 125 EIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDIRNG 184
Query: 2726 HINGEN--YSYRGSVVYQCNAGFRLIGMSVRICQQDHH----WSGKTPFCVLVSCGHPGS 2779
+GE Y+Y SV Y C+ F L+G + C ++ W P C ++C P
Sbjct: 185 RHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITCRKPDV 244
Query: 2780 PPHSQMSGDS--YTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGD 2837
+SG Y + + C L G+S C D W S P C S
Sbjct: 245 SHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSC--INL 302
Query: 2838 PGIPAHGIRL------GDSFDPGTVMRFSCEAGHVLRGSSERT--CQANGSWSGSQPECG 2889
P IP D + GTV+R+ C G+ T CQ N W+ Q C
Sbjct: 303 PDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWTPYQG-CE 361
Query: 2890 VISCGNP------------GTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVN 2937
+ C P P+N V F + I + C E T S C +
Sbjct: 362 ALCCPEPKLNNGEITQHRKSRPANHCVYF-----YGDEISFSCHE----TSRFSAICQGD 412
Query: 2938 GTWTGSDPECLVINCGDPGIPANGLRLGNDFRYNKT-VTYQCVPGYMMESHRVSVLSCTK 2996
GTW+ P C I P I + + + + K + Y+C GY++ + LSC+
Sbjct: 413 GTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQ--AKLSCSY 470
Query: 2997 DRTWNGTKPVCKALMCKPPPLIPNGKVVGSD-FMWGSSVTYACLEGYQLSLPAVFTCEGN 3055
W+ P CKAL C+ P L+ V D ++ +VT C GY + P TC GN
Sbjct: 471 SH-WSAPAPQCKAL-CRKPELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGN 528
Query: 3056 GSWTGELPQC 3065
+W E+P+C
Sbjct: 529 RTWYPEVPKC 538
Score = 139 bits (349), Expect = 6e-32
Identities = 126/453 (27%), Positives = 177/453 (39%), Gaps = 59/453 (13%)
Query: 2468 CSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQ 2527
C P +G + +T G I F C+ G+ L+G + + C +G WS +P C+
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVG-WSHPLPQCE 171
Query: 2528 ALSCGLPEAPKNGMVFGKE--YTVGTKAMYSCSEGYHL--QAGAEATAECLDTGLWSNRN 2583
+ C P +NG G+E Y G YSC + L A T E G+W R
Sbjct: 172 IVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVW--RP 229
Query: 2584 VPPQCVPVTC--PDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQAN 2641
PP C +TC PDVS HG F Y ++ ++ C G+ G VI C A+
Sbjct: 230 SPPTCEKITCRKPDVS-----HGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDAD 284
Query: 2642 GKWSLGDSTPTCRIISCGELPIPPNGH-----RIGTLSVY--GATAIFSCNSGY--TLVG 2692
KW+ S P C SC LP P+ R VY G + C+ GY T
Sbjct: 285 SKWN--PSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDE 342
Query: 2693 SRVRECMANGLWS---GSEVRCLAGHCGTPEP-IVNGHINGEN---------YSYRGSVV 2739
C N W+ G E C PEP + NG I Y Y +
Sbjct: 343 PTTVICQKNLRWTPYQGCEALC------CPEPKLNNGEITQHRKSRPANHCVYFYGDEIS 396
Query: 2740 YQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPH---SQMSGDSYTVGAVV 2796
+ C+ R ICQ D WS +TP C + C P H Q S S+ ++
Sbjct: 397 FSCHETSRFSA----ICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSFFKEEII 451
Query: 2797 RYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLG-DSFDPGT 2855
Y C LVG + C HW+ P C +C P + + + D +
Sbjct: 452 -YECDKGYILVGQAKLSCSY-SHWSAPAPQCK----ALCRKPELVNGRLSVDKDQYVEPE 505
Query: 2856 VMRFSCEAGHVLRGSSERTCQANGSWSGSQPEC 2888
+ C++G+ + G TC N +W P+C
Sbjct: 506 NVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKC 538
Score = 124 bits (312), Expect = 1e-27
Identities = 94/315 (29%), Positives = 142/315 (45%), Gaps = 34/315 (10%)
Query: 2951 NCGDP-----GIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKP 3005
NCG P P + F+ T+ Y C+PGY+ SH L+C D W
Sbjct: 49 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYV-RSHSTQTLTCNSDGEWV-YNT 106
Query: 3006 VCKALMCKPPPLIPNGKV-VGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNG---SWTGE 3061
C C+ P + NG+V + +D +GS + ++C EG+ L CE W+
Sbjct: 107 FCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHP 166
Query: 3062 LPQCFPVFCGDPGVPSRGRR--EDRGFSYRSSVSFSCHPPLVLVGSPRRFC----QSDGT 3115
LPQC V C P GR E+ ++Y SV++SC P L+G C ++ G
Sbjct: 167 LPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGV 226
Query: 3116 WSGTQPSCIDPTLTTCADPGVPQFGIQNNSQG--YQVGSTVLFRCQKGYLLQGSTTRTCL 3173
W + P+C TC P V G + G Y T++F+CQKG++L+GS+ C
Sbjct: 227 WRPSPPTC---EKITCRKPDVSH-GEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCD 282
Query: 3174 PNLTWSGTPPDCVPHHC-RQPETP-----THANVGALDLPSMGYTLIYSCQEGFSLKGGS 3227
+ W+ +PP C P+ C P+ P T+ D+ +G L Y C G+ K +
Sbjct: 283 ADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGY--KPTT 340
Query: 3228 EHRT---CKADGSWT 3239
+ T C+ + WT
Sbjct: 341 DEPTTVICQKNLRWT 355
Score = 114 bits (285), Expect = 2e-24
Identities = 104/390 (26%), Positives = 163/390 (41%), Gaps = 46/390 (11%)
Query: 2892 SCGNPGTPSNAR----VVFSDGLVFSSSIVYECREGY---YATGLLSRHCSVNGTWTGSD 2944
+CG P T S A + +++ Y C GY ++T L+ C+ +G W +
Sbjct: 49 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLT--CNSDGEWV-YN 105
Query: 2945 PECLVINCGDPGIPANG-LRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRT--WN 3001
C+ C PG NG + + D + + + C G+ + S +DR W+
Sbjct: 106 TFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCE-VQDRGVGWS 164
Query: 3002 GTKPVCKALMCKPPPLIPNGKVVGSD--FMWGSSVTYACLEGYQLSLPAVFTC----EGN 3055
P C+ + CKPPP I NG+ G + + +G SVTY+C + L A +C E
Sbjct: 165 HPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETI 224
Query: 3056 GSWTGELPQCFPVFCGDPGVPSRGRREDRG--FSYRSSVSFSCHPPLVLVGSPRRFCQSD 3113
G W P C + C P V G ++Y+ ++ F C VL GS C +D
Sbjct: 225 GVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDAD 284
Query: 3114 GTWSGTQPSCIDPTLTTCAD-PGVPQFGIQN-----NSQGYQVGSTVLFRCQKGY--LLQ 3165
W+ + P+C +P +C + P +P + Y VG+ + +RC GY
Sbjct: 285 SKWNPSPPAC-EPN--SCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTD 341
Query: 3166 GSTTRTCLPNLTWSGTP-PDCVPHHCRQPETPTHANVGAL-----DLPSMGYTLIYSCQE 3219
TT C NL W TP C C +P+ N G + P+ Y +
Sbjct: 342 EPTTVICQKNLRW--TPYQGCEALCCPEPKL----NNGEITQHRKSRPANHCVYFYGDEI 395
Query: 3220 GFSLKGGSEHRT-CKADGSWTGKPPICLEV 3248
FS S C+ DG+W+ + P C ++
Sbjct: 396 SFSCHETSRFSAICQGDGTWSPRTPSCGDI 425
Score = 53.1 bits (126), Expect = 5e-06
Identities = 113/492 (22%), Positives = 185/492 (37%), Gaps = 73/492 (14%)
Query: 670 TDHSTGKRGFNITFTTFRHNECPDPGVPVNGK-RFGDSLQLGSSISFLCDEGFLGTQGSE 728
T +S G+ +N TF ++ C PG NG+ L GS I F C EGF GS
Sbjct: 95 TCNSDGEWVYN-TFCIYKR--CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFF-LIGST 150
Query: 729 TITCVLKEGSVVWNSAVLRCE-APCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPG 787
T C +++ V W+ + +CE C +G G FY S + P
Sbjct: 151 TSRCEVQDRGVGWSHPLPQCEIVKCKPPPDIRNGR--HSGEENFYAYGFSVTY--SCDPR 206
Query: 788 YPIKITFDRFKTEVNYDTLEVRDGRTYSAPLI-----GVYHGTQVPQF---------LIS 833
+ + + V +T+ V + I V HG V F ++
Sbjct: 207 FSL-LGHASISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVF 265
Query: 834 TSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLD-PGIP-----VNGQRHGNDFY-VG 886
++L + H D + + + C++ P IP + D Y VG
Sbjct: 266 KCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVG 325
Query: 887 ALVTFSCDSGYTLSDGEP--LECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFY 944
++ + C GY + EP + C+ N +W+ CEALC + ++G I
Sbjct: 326 TVLRYRCHPGYKPTTDEPTTVICQKNLRWT-PYQGCEALCCPEPKLNNGEITQ--HRKSR 382
Query: 945 PNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGS--RLPAPI 1002
P N +C + +G + F+ H E+ + +G+++ P G P I
Sbjct: 383 PAN-HCVYF----YGDEISFSCH----ETSRFSAICQGDGTWS-PRTPSCGDICNFPPKI 432
Query: 1003 SAG------LYGNFTAQVRFISDFSMSYEG---FNITFSEYDLEP------CEEPEV--P 1045
+ G Y F ++ + D G + ++S + C +PE+
Sbjct: 433 AHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYSHWSAPAPQCKALCRKPELVNG 492
Query: 1046 AYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAE----CGNS 1101
S+ K Q+ + +T C GY + G ITC G R W +P+C E C
Sbjct: 493 RLSVDKD-QYVEPENVTIQCDSGYGVVGPQSITCSG--NRTWYPEVPKCEWETPEGCEQV 549
Query: 1102 VTGTQGTLLSPN 1113
+TG + PN
Sbjct: 550 LTGKRLMQCLPN 561
Score = 50.1 bits (118), Expect = 4e-05
Identities = 26/60 (43%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
Query: 1385 CNDPGIPQNGSRSGDS--WEAGDSTVFQCDPGYALQGSAEISC-VKIENRFFWQPSPPTC 1441
C P +NG SG+ + G S + CDP ++L G A ISC V+ E W+PSPPTC
Sbjct: 175 CKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTC 234
Score = 45.1 bits (105), Expect = 0.001
Identities = 58/274 (21%), Positives = 95/274 (34%), Gaps = 48/274 (17%)
Query: 2121 QECPDPEPFANGIVR-GAGYNVGQSVTFECLPGYQLTGHPVLTCQ-HGTNRNWDHPLPKC 2178
+ C P NG V + G + F C G+ L G C+ W HPLP+C
Sbjct: 111 KRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQC 170
Query: 2179 E-VPCGGNITSSNG------TVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP 2231
E V C NG Y+ GF YS L GH + +
Sbjct: 171 EIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLL-----GH------ASISCTV 219
Query: 2232 SGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSS-------SNQVLLKFHRDAATGGIFAI 2284
+ I +W T ++ ++ + S + ++ K + G I
Sbjct: 220 ENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVI 279
Query: 2285 AFSAYPLTKCPPPTILPNAEV---------------VTENEEFNIGDIVRYRCLPGFTLV 2329
A PP PN+ + T+ + + +G ++RYRC PG+
Sbjct: 280 HCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPT 339
Query: 2330 GNE---ILTCKLGTYLQFEGPPPICEVHCPTNEL 2360
+E ++ K + ++G +C CP +L
Sbjct: 340 TDEPTTVICQKNLRWTPYQGCEALC---CPEPKL 370
Score = 44.3 bits (103), Expect = 0.002
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 139 CGNPGRLPNG-IQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
C +PG L NG ++ + + G ++ +SC+ GFFL G C + W PLP C
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEV-QDRGVGWSHPLPQC 170
Score = 44.3 bits (103), Expect = 0.002
Identities = 65/279 (23%), Positives = 94/279 (33%), Gaps = 75/279 (26%)
Query: 1384 SCNDPGIPQNGSRSGDS--WEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC 1441
+C P + SG + D+ VF+C G+ L+GS+ I C + W PSPP C
Sbjct: 238 TCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHC---DADSKWNPSPPAC 294
Query: 1442 IAPCGGDLTGPSGVILSPNYP----EPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYD 1497
P+ I P+ P E YP + T YV+ V + PGY
Sbjct: 295 ---------EPNSCINLPDIPHASWETYP-------RPTKEDVYVVGTVLR-YRCHPGYK 337
Query: 1498 ---------------FLHIYDGRDSL---SPLIGS-----------------FYGSQLPG 1522
Y G ++L P + + FYG ++
Sbjct: 338 PTTDEPTTVICQKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISF 397
Query: 1523 RIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSIKNG--TRVGSDLKLGSSV 1580
+S R A G T + + C P I +G + S +
Sbjct: 398 SCHETS-------RFSAICQGDGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEI 450
Query: 1581 TYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPC 1619
Y C GY + G + LSC W+ P P C A C
Sbjct: 451 IYECDKGYILVGQAKLSCSYSH-----WSAPAPQCKALC 484
Score = 43.9 bits (102), Expect = 0.003
Identities = 54/223 (24%), Positives = 84/223 (37%), Gaps = 67/223 (30%)
Query: 1054 QFGVGDTLTFSCFPGY-RLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSP 1112
+F G TL ++C PGY R T +TC
Sbjct: 70 RFKTGTTLKYTCLPGYVRSHSTQTLTC--------------------------------- 96
Query: 1113 NFPVNYNNNHECIYSIQTQPGK----GIQLKARAFELSEGDVLKVYDGNNNSARLLGVFS 1168
N + N CIY PG+ +++K +LS G ++ FS
Sbjct: 97 NSDGEWVYNTFCIYKRCRHPGELRNGQVEIKT---DLSFGSQIE--------------FS 139
Query: 1169 HSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGH 1228
SE + ++TS + ++ G+ E++KC+ P + G +E
Sbjct: 140 CSEGFFLIGSTTSRC-------EVQDRGVGWSHPLPQCEIVKCKPPPDIRNGRHSGEENF 192
Query: 1229 FA-GSSVSFSCDPGYSLRGSEELLCLSGERRT---WDRPLPTC 1267
+A G SV++SCDP +SL G + C + E T W PTC
Sbjct: 193 YAYGFSVTYSCDPRFSLLGHASISC-TVENETIGVWRPSPPTC 234
Score = 43.9 bits (102), Expect = 0.003
Identities = 63/292 (21%), Positives = 111/292 (38%), Gaps = 62/292 (21%)
Query: 1908 SCPEPAVPSNGVKTGERYLVN--DVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCI 1965
+C +P V + +G + N D + F+C+ G+ L+G + I C + +WN PP C
Sbjct: 238 TCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADS--KWNPSPPAC- 294
Query: 1966 AQCGGTVEEMEGVILSPGFP----GNYP-SNMDCSWKIALPVGFGAHIQFLNFSTEPNHD 2020
E I P P YP + + + + + H + + EP
Sbjct: 295 --------EPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTV 346
Query: 2021 YIE--IRNGPYETSRMM----GRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ 2074
+ +R PY+ + + + E+ S VYF+ D
Sbjct: 347 ICQKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGD------------- 393
Query: 2075 DLTYS-HQISSFLRGFDLSELERTNSTPPVAASYVWD-LDPGCEAYELQECPDPEPFANG 2132
++++S H+ S F S + + + T W P C C P A+G
Sbjct: 394 EISFSCHETSRF------SAICQGDGT--------WSPRTPSCG----DICNFPPKIAHG 435
Query: 2133 -IVRGAGYN-VGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPC 2182
+ + Y+ + + +EC GY L G L+C + +W P P+C+ C
Sbjct: 436 HYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYS---HWSAPAPQCKALC 484
Score = 41.6 bits (96), Expect = 0.014
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Query: 340 HNMCPDPGIPERGK-RLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRP 398
+ C PG G+ + +D GS ++F+C+EG+ L GS C +V D WS P
Sbjct: 110 YKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRC-EVQDRGVGWSHPLP 168
Query: 399 VCRARMC 405
C C
Sbjct: 169 QCEIVKC 175
Score = 39.7 bits (91), Expect = 0.053
Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 4/60 (6%)
Query: 1909 CPEPAVPSNGVKTGER--YLVNDVVSFQCEPGYALQGHAHISCM--PGTVRRWNYPPPLC 1964
C P NG +GE Y V++ C+P ++L GHA ISC T+ W PP C
Sbjct: 175 CKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTC 234
Score = 39.7 bits (91), Expect = 0.053
Identities = 21/79 (26%), Positives = 33/79 (41%), Gaps = 16/79 (20%)
Query: 534 GSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPN 593
G +++ DT+ F+CQ F L G I C +++W+ P C P+ + P+
Sbjct: 254 GPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPAC---------EPNSCINLPD 304
Query: 594 YPEDYGNHLHCVWLILARP 612
P H W RP
Sbjct: 305 IP-------HASWETYPRP 316
Score = 38.9 bits (89), Expect = 0.090
Identities = 18/68 (26%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 1727 VPRTSATQCSSVPEPRYGKRLGSD--FSVGAIVRFECNSGYALQGSPEIECLPVPGALAQ 1784
+P+ +C P+ R G+ G + ++ G V + C+ ++L G I C +
Sbjct: 167 LPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGV 226
Query: 1785 WNVSAPTC 1792
W S PTC
Sbjct: 227 WRPSPPTC 234
Score = 37.7 bits (86), Expect = 0.20
Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 11/88 (12%)
Query: 2119 ELQECPDPEPFANGIVRGAG--YNVGQSVTFECLPGYQLTGHPVLTC--QHGTNRNWDHP 2174
E+ +C P NG G Y G SVT+ C P + L GH ++C ++ T W
Sbjct: 171 EIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPS 230
Query: 2175 LPKCE-VPC------GGNITSSNGTVYS 2195
P CE + C G + S G +Y+
Sbjct: 231 PPTCEKITCRKPDVSHGEMVSGFGPIYN 258
Score = 36.2 bits (82), Expect = 0.58
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 2/60 (3%)
Query: 139 CGNPGRLPNGIQQGST--FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
C P + NG G + G V YSC+ F L GHA ++C +E W P+C
Sbjct: 175 CKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTC 234
Score = 36.2 bits (82), Expect = 0.58
Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 2/60 (3%)
Query: 1558 CFDPGSIKNGTRVGSD--LKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVC 1615
C P I+NG G + G SVTY C + + G +++SC + + VW P C
Sbjct: 175 CKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTC 234
Score = 35.0 bits (79), Expect = 1.3
Identities = 18/62 (29%), Positives = 34/62 (54%), Gaps = 7/62 (11%)
Query: 139 CGNPGRLPNG-IQQGSTFNL-GDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
C P ++ +G +Q S+++ +++ Y C+ G+ L G A L+C + + W P P C
Sbjct: 426 CNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSC-----SYSHWSAPAPQC 480
Query: 197 RA 198
+A
Sbjct: 481 KA 482
Score = 34.3 bits (77), Expect = 2.2
Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 6/74 (8%)
Query: 507 LGFKASYEEIEQGSCGDPGIPAYGRREGSR--FHHGDTLKFECQPAFELVGQKAITCQKN 564
+G+ + E C P GR G + +G ++ + C P F L+G +I+C
Sbjct: 161 VGWSHPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVE 220
Query: 565 NQ----WSAKKPGC 574
N+ W P C
Sbjct: 221 NETIGVWRPSPPTC 234
Score = 34.3 bits (77), Expect = 2.2
Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 7/69 (10%)
Query: 2113 PGCEAYELQECPDPEPFANGIVRGAG--YNVGQSVTFECLPGYQLTGHPVLTCQHGTNRN 2170
P CE C P+ +V G G YN ++ F+C G+ L G V+ C +
Sbjct: 232 PTCEKIT---CRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCD--ADSK 286
Query: 2171 WDHPLPKCE 2179
W+ P CE
Sbjct: 287 WNPSPPACE 295
Score = 33.9 bits (76), Expect = 2.9
Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 10/63 (15%)
Query: 138 TCGNP----GRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPL 193
TC P G + +G G +N D + + C GF L G +V+ C A S+ W+
Sbjct: 238 TCRKPDVSHGEMVSGF--GPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSK----WNPSP 291
Query: 194 PSC 196
P+C
Sbjct: 292 PAC 294
Score = 33.9 bits (76), Expect = 2.9
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 5/69 (7%)
Query: 1405 DSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPC-GGDLTGPSGVILSPNYPE 1463
+ +++CD GY L G A++SC + W P C A C +L + Y E
Sbjct: 448 EEIIYECDKGYILVGQAKLSC----SYSHWSAPAPQCKALCRKPELVNGRLSVDKDQYVE 503
Query: 1464 PYPPGKECD 1472
P +CD
Sbjct: 504 PENVTIQCD 512
Score = 33.5 bits (75), Expect = 3.8
Identities = 16/65 (24%), Positives = 26/65 (40%), Gaps = 2/65 (3%)
Query: 343 CPDPGIPERGKRLGSD--FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVC 400
C P G+ G + + G SV ++C+ + L G I+C ++ W P C
Sbjct: 175 CKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTC 234
Query: 401 RARMC 405
C
Sbjct: 235 EKITC 239
Score = 33.5 bits (75), Expect = 3.8
Identities = 17/51 (33%), Positives = 20/51 (39%), Gaps = 3/51 (5%)
Query: 1221 YKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAEC 1271
YK F + + CD GY L G +L C W P P C A C
Sbjct: 437 YKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYSH---WSAPAPQCKALC 484
Score = 33.1 bits (74), Expect = 5.0
Identities = 20/73 (27%), Positives = 34/73 (46%), Gaps = 7/73 (9%)
Query: 1723 VYQAVPRTSATQCSSVPEPRYGKRL---GSDFSVGAIVRFECNSGYALQGSPEIECLPVP 1779
V++ P T P+ +G+ + G ++ + F+C G+ L+GS I C
Sbjct: 226 VWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHC---- 281
Query: 1780 GALAQWNVSAPTC 1792
A ++WN S P C
Sbjct: 282 DADSKWNPSPPAC 294
Score = 33.1 bits (74), Expect = 5.0
Identities = 55/251 (21%), Positives = 87/251 (34%), Gaps = 28/251 (11%)
Query: 1057 VGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLS--PNF 1114
VG L + C PGY+ T + + W+ P C A C G + +
Sbjct: 324 VGTVLRYRCHPGYKPTTDEPTTVICQKNLRWT-PYQGCEALCCPEPKLNNGEITQHRKSR 382
Query: 1115 PVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMG 1174
P N+ C+Y + +R + +GD + S + F G
Sbjct: 383 PANH-----CVYFYGDEISFSCHETSRFSAICQGD--GTWSPRTPSCGDICNFPPKIAHG 435
Query: 1175 VTLNSTSSSLWLDFITDAENTSKGFEL-----------HFSSFE---LIKCEDPGTPKFG 1220
S+S S + + I KG+ L H+S+ C P
Sbjct: 436 HYKQSSSYSFFKEEII--YECDKGYILVGQAKLSCSYSHWSAPAPQCKALCRKPELVNGR 493
Query: 1221 YKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECGGTVRGEVS 1280
V + + +V+ CD GY + G + + C SG RTW +P C E ++
Sbjct: 494 LSVDKDQYVEPENVTIQCDSGYGVVGPQSITC-SG-NRTWYPEVPKCEWETPEGCEQVLT 551
Query: 1281 GQVLSPGYPAP 1291
G+ L P P
Sbjct: 552 GKRLMQCLPNP 562
Score = 33.1 bits (74), Expect = 5.0
Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 7/65 (10%)
Query: 520 SCGD----PGIPAYG--RREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPG 573
SCGD P A+G ++ S + + +EC + LVGQ ++C ++ WSA P
Sbjct: 421 SCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYSH-WSAPAPQ 479
Query: 574 CVFSC 578
C C
Sbjct: 480 CKALC 484
>gi|13899255 membrane frizzled-related protein [Homo sapiens]
Length = 579
Score = 123 bits (309), Expect = 3e-27
Identities = 88/301 (29%), Positives = 137/301 (45%), Gaps = 42/301 (13%)
Query: 1789 APTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQV----VSFVTE 1844
+P+ CGG L+ RG SP +P+PY + +CVW I V IQ+++ + V
Sbjct: 137 SPSPQSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVAS 196
Query: 1845 QNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 1904
+D LE+ + + + G P LN+ ++ L + F SD SV GFH Y+ +
Sbjct: 197 CLFDRLELSPEPEGPLLRV---CGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAM 253
Query: 1905 GLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLC 1964
P G + + + ++ P G A+ C G+ C
Sbjct: 254 A---------PGRGSCAHDEFRCDQLICLL--PDSVCDGFAN--CADGS------DETNC 294
Query: 1965 IAQ---CGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEP---- 2017
A+ CGG + ++G +P + YP + C+W I++P G +QF NFS E
Sbjct: 295 SAKFSGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDEC 354
Query: 2018 NHDYIEIRNGPYETS-----RMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLE 2072
DY+E+ YETS ++GRF G+E P L+S+ HE V F +DH + GF
Sbjct: 355 KFDYVEV----YETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSAT 410
Query: 2073 Y 2073
Y
Sbjct: 411 Y 411
Score = 110 bits (274), Expect = 3e-23
Identities = 95/309 (30%), Positives = 134/309 (43%), Gaps = 40/309 (12%)
Query: 10 PRWQVQSHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQ 69
P+ Q +S S C L GP G SP +P YP +C W I H IQL +
Sbjct: 128 PKGQQESGVSPSPQSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIE 187
Query: 70 SFALEED----FDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQ 125
+ ++E FD L + P+PE R+ G P T+ + A+ L + +SD +V
Sbjct: 188 ALSIESVASCLFDRLEL---SPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGF 244
Query: 126 GFHATYEVLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNL-GFFLEGHAVLTCHAGSE 184
GFHA Y+ + PGR G F + C L +G A C GS+
Sbjct: 245 GFHAWYQAMA------PGR---GSCAHDEFRCDQLI---CLLPDSVCDGFA--NCADGSD 290
Query: 185 NSATWDFPLPSCRAD-DACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALV 243
+ +C A CGG L G G S+P + +Y + CTW I G +I L
Sbjct: 291 ET--------NCSAKFSGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQ 342
Query: 244 FIDFQLED----GYDFLEVTGTEGSSLW-----FTGASLPAPVISSKNWLRLHFTSDGNH 294
F +F LE +D++EV T S + F GA P ++SS + L + F +D
Sbjct: 343 FHNFSLEAQDECKFDYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGI 402
Query: 295 RQRGFSAQY 303
GFSA Y
Sbjct: 403 SSGGFSATY 411
Score = 102 bits (253), Expect = 9e-21
Identities = 86/307 (28%), Positives = 131/307 (42%), Gaps = 41/307 (13%)
Query: 1265 PTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHD 1324
P+ + CGG + G G SP YP PY N +C+W I+ I L E V
Sbjct: 138 PSPQSTCGGLLSGP-RGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVAS 196
Query: 1325 VL--RIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTA 1382
L R+ P G LL+ + G P L++ + +++ F +D GF +
Sbjct: 197 CLFDRLELSPEPEGPLLR-VCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMA- 254
Query: 1383 TSCNDPGIPQNGSRSGDSWEAGDSTVFQCDP---GYA--LQGSAEISCVKIENRFFWQPS 1437
P GS + D + D G+A GS E +C
Sbjct: 255 --------PGRGSCAHDEFRCDQLICLLPDSVCDGFANCADGSDETNC------------ 294
Query: 1438 PPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP--- 1494
+ CGG+LTG G +P+Y + YP C W ++V + I L F+ F+LE
Sbjct: 295 -SAKFSGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDE 353
Query: 1495 -GYDFLHIYDGRDS-LSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDY-- 1550
+D++ +Y+ S L+G F G++ P + SS + L + FR+D +S+ GF Y
Sbjct: 354 CKFDYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLA 413
Query: 1551 ---TENP 1554
TENP
Sbjct: 414 FNATENP 420
Score = 94.7 bits (234), Expect = 1e-18
Identities = 78/296 (26%), Positives = 118/296 (39%), Gaps = 27/296 (9%)
Query: 405 CDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGD 464
C L GP G +SPN+P Y N HCVW I I+L E +E L
Sbjct: 144 CGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVAT-DHAIQLKIEALSIESVASCLFDRL 202
Query: 465 GGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDP 524
+ +L + P L + +H + ++F +D S GF A Y+ + G
Sbjct: 203 ELSPEPEGPLLRVCGRVPPPTLNTNASH-LLVVFVSDSSVEGFGFHAWYQAMAPG----- 256
Query: 525 GIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGC---VFSCFFN 581
GS H +F C L+ N + + C C N
Sbjct: 257 --------RGSCAHD----EFRCDQLICLLPDSVCDGFANCADGSDETNCSAKFSGCGGN 304
Query: 582 FTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQ----FDFLVIKDG 637
T G +P+Y + Y + L C W I I L F++ +E Q FD++ + +
Sbjct: 305 LTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVEVYET 364
Query: 638 ATAEA-PVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECP 692
+++ A +LG F G + P + SS H + F+TDH GF+ T+ F E P
Sbjct: 365 SSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNATENP 420
Score = 94.0 bits (232), Expect = 2e-18
Identities = 83/316 (26%), Positives = 123/316 (38%), Gaps = 34/316 (10%)
Query: 563 KNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFND 622
K Q S P +C + P G SPNYP+ Y + HCVW I + I L
Sbjct: 129 KGQQESGVSPSPQSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEA 188
Query: 623 IDVEPQFDFLV--IKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFN 680
+ +E L ++ E P+L P+ T++ H+ + F +D S GF+
Sbjct: 189 LSIESVASCLFDRLELSPEPEGPLLRVCGRVPPPTLNTNASHLL-VVFVSDSSVEGFGFH 247
Query: 681 ITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCD---EGFLG-TQGSETITCVLKE 736
+ P G D + I L D +GF GS+ C K
Sbjct: 248 AWYQAM---------APGRGSCAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAKF 298
Query: 737 GSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDR 796
CGG+LT GT +P + Y L C W I G+ I++ F
Sbjct: 299 SG-------------CGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHN 345
Query: 797 F----KTEVNYDTLEVRDGRTYSA-PLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDI 851
F + E +D +EV + + A L+G + G + P L+S+ + L +LF TD S
Sbjct: 346 FSLEAQDECKFDYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSG 405
Query: 852 GFQLRYETITLQSDHC 867
GF Y + C
Sbjct: 406 GFSATYLAFNATENPC 421
Score = 84.7 bits (208), Expect = 1e-15
Identities = 79/314 (25%), Positives = 128/314 (40%), Gaps = 46/314 (14%)
Query: 749 EAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTE----VNYD 804
++ CGG L+ P G SP +P Y C W I+ + I++ + E +D
Sbjct: 141 QSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFD 200
Query: 805 TLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQS 864
LE+ PL+ V G P L + +++L ++F +D S GF Y+ +
Sbjct: 201 RLELSPEP--EGPLLRVC-GRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMA--- 254
Query: 865 DHCLDPGIPVNGQRHGNDFYVGALVTFS----CDSGYTLSDG-EPLECEPNFQWSRALPS 919
P G ++F L+ CD +DG + C F
Sbjct: 255 --------PGRGSCAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAKFSG------ 300
Query: 920 CEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLES----GH 975
CGG + G GT +P + YP+ L CTW I G + FH F LE+
Sbjct: 301 ----CGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKF 356
Query: 976 DYLLITE---NGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFS 1032
DY+ + E +G+F+ L + G+ P + + + V F +D +S GF+ T+
Sbjct: 357 DYVEVYETSSSGAFSL-LGRFCGAEPPPHL---VSSHHELAVLFRTDHGISSGGFSATYL 412
Query: 1033 EYDL--EPCEEPEV 1044
++ PC E+
Sbjct: 413 AFNATENPCGPSEL 426
Score = 83.6 bits (205), Expect = 3e-15
Identities = 88/329 (26%), Positives = 133/329 (40%), Gaps = 63/329 (19%)
Query: 1610 NPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALN 1669
+P P T CGG G G SPNYP Y C++ + V D+ A+
Sbjct: 137 SPSPQST--CGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDH-----------AIQ 183
Query: 1670 DVVEVHDGHSQHSRLLSSLSGSHTGES--------LPLATSN----QVLIKFSAKGLAPA 1717
+E S S L L S E +P T N +L+ F +
Sbjct: 184 LKIEALSIESVASCLFDRLELSPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEG 243
Query: 1718 RGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNS---GYA--LQGSPE 1772
GFH YQA+ P G +F ++ +S G+A GS E
Sbjct: 244 FGFHAWYQAMA------------PGRGSCAHDEFRCDQLICLLPDSVCDGFANCADGSDE 291
Query: 1773 IECLPVPGALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGA 1832
C A+++ CGGNLT +GT +P + + Y + L C W I VP G
Sbjct: 292 TNCS------AKFS--------GCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGH 337
Query: 1833 GIQIQVVSFVTEQN----WDSLEVFD-GADNTVTMLGSFSGTTVPALLNSTSNQLYLHFY 1887
I++Q +F E +D +EV++ + ++LG F G P L S+ ++L + F
Sbjct: 338 SIELQFHNFSLEAQDECKFDYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFR 397
Query: 1888 SDISVSAAGFHLEYKTVGLSSCPEPAVPS 1916
+D +S+ GF Y + ++ P PS
Sbjct: 398 TDHGISSGGFSATY--LAFNATENPCGPS 424
Score = 80.1 bits (196), Expect = 4e-14
Identities = 93/341 (27%), Positives = 133/341 (39%), Gaps = 53/341 (15%)
Query: 1082 GRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKAR 1141
G++ SP P+ + CG ++G +G SPN+P Y N C++ IQ IQLK
Sbjct: 130 GQQESGVSPSPQ--STCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIE 187
Query: 1142 AFELSEGDVLKVYDGNNNSARLLGVFSH--SEMMGVTLNSTSSSLWLDFITDAENTSKGF 1199
A + E ++D S G + TLN+ +S L + F++D+ GF
Sbjct: 188 ALSI-ESVASCLFDRLELSPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGF 246
Query: 1200 ELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCL------ 1253
+ + P G HDE F CD +L+CL
Sbjct: 247 HAWYQAM---------APGRGSCAHDE---------FRCD---------QLICLLPDSVC 279
Query: 1254 SGERRTWDRPLPT-CVAE---CGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCT 1309
G D T C A+ CGG + G + G +P Y Y H L C W I AG +
Sbjct: 280 DGFANCADGSDETNCSAKFSGCGGNLTG-LQGTFSTPSYLQQYPHQLLCTWHISVPAGHS 338
Query: 1310 IGLHFLVFDTEE----VHDVLRIWDGPVESGV--LLKELSGPALPKDLHSTFNSVVLQFS 1363
I L F F E D + +++ SG LL G P L S+ + + + F
Sbjct: 339 IELQFHNFSLEAQDECKFDYVEVYE-TSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFR 397
Query: 1364 TDFFTSKQGFAIQFSVSTATS--CNDPGIP-QNGSRSGDSW 1401
TD S GF+ + AT C + Q G G W
Sbjct: 398 TDHGISSGGFSATYLAFNATENPCGPSELSCQAGGCKGVQW 438
Score = 73.9 bits (180), Expect = 3e-12
Identities = 84/328 (25%), Positives = 125/328 (38%), Gaps = 76/328 (23%)
Query: 202 CGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG----YDFLE 257
CGG L G G SSP++P Y N C W I I L +E +D LE
Sbjct: 144 CGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRLE 203
Query: 258 VTGT-EGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGV 316
++ EG L G P + ++ + L + F SD + GF A YQ
Sbjct: 204 LSPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAM---------- 253
Query: 317 KLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQ 376
P RG +FR C++
Sbjct: 254 -------------------------------APGRGSCAHDEFR--------CDQ----- 269
Query: 377 GSKRITCM---KVSDMFAAWSD--HRPVCRARM--CDAHLRGPSGIITSPNFPIQYDNNA 429
+ C+ V D FA +D C A+ C +L G G ++P++ QY +
Sbjct: 270 ----LICLLPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGLQGTFSTPSYLQQYPHQL 325
Query: 430 HCVWIITALNPSKVIKLAFEEFDLER----GYDTLTVGDGGQDGDQKTVLYILTGTSVPD 485
C W I ++ I+L F F LE +D + V + G ++L G P
Sbjct: 326 LCTWHI-SVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSG-AFSLLGRFCGAEPPP 383
Query: 486 LIVSTNHQMWLLFQTDGSGSSLGFKASY 513
+VS++H++ +LF+TD SS GF A+Y
Sbjct: 384 HLVSSHHELAVLFRTDHGISSGGFSATY 411
Score = 71.6 bits (174), Expect = 1e-11
Identities = 77/305 (25%), Positives = 121/305 (39%), Gaps = 44/305 (14%)
Query: 2176 PKCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGD- 2234
P + CGG ++ G SP +P PY + CVW I V H ++L + L E
Sbjct: 138 PSPQSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASC 197
Query: 2235 -FITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTK 2293
F + P+ P L V R + T+ ++++ +L+ F D++ G F A+
Sbjct: 198 LFDRLELSPEPEGPLLRVCGR-VPPPTLNTNASHLLVVFVSDSSVEG---FGFHAWYQAM 253
Query: 2294 CPPPTILPNAEVVTENEEFNIGDIVRYRCL------PGFT--LVGNEILTCKLGTYLQFE 2345
P ++EF ++ CL GF G++ C +F
Sbjct: 254 AP-------GRGSCAHDEFRCDQLI---CLLPDSVCDGFANCADGSDETNCS----AKFS 299
Query: 2346 GPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSE 2405
G C N LT G + SY YP C+W + V ++I L F E
Sbjct: 300 G--------CGGN--LTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLE 349
Query: 2406 KQ----YDEFEIFD-GPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFK 2460
Q +D E+++ SG LL G P +V SS + + + + +DH + GF
Sbjct: 350 AQDECKFDYVEVYETSSSGAFSLLGRFCGAEPPPHLV-SSHHELAVLFRTDHGISSGGFS 408
Query: 2461 IRYSA 2465
Y A
Sbjct: 409 ATYLA 413
Score = 70.1 bits (170), Expect = 4e-11
Identities = 82/307 (26%), Positives = 128/307 (41%), Gaps = 36/307 (11%)
Query: 912 QWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHL 971
Q S PS ++ CGG + G G SP +PD YP N +C W I+ + + +
Sbjct: 132 QESGVSPSPQSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSI 191
Query: 972 ESGHDYLL--ITENGSFTQPLRQLTGSRLPAPISAGLYGNFT-AQVRFISDFSMSYEGFN 1028
ES L + + PL ++ G R+P P L N + V F+SD S+ GF+
Sbjct: 192 ESVASCLFDRLELSPEPEGPLLRVCG-RVPPPT---LNTNASHLLVVFVSDSSVEGFGFH 247
Query: 1029 ITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWS 1088
+ + P +F + P +G A C G
Sbjct: 248 AWY---------QAMAPGRGSCAHDEFRCDQLICL--LPDSVCDGFA--NCADG------ 288
Query: 1089 SPLPRCVAE---CGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFEL 1145
S C A+ CG ++TG QGT +P++ Y + C + I G I+L+ F L
Sbjct: 289 SDETNCSAKFSGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSL 348
Query: 1146 S-----EGDVLKVYDGNNNSA-RLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGF 1199
+ D ++VY+ +++ A LLG F +E L S+ L + F TD +S GF
Sbjct: 349 EAQDECKFDYVEVYETSSSGAFSLLGRFCGAE-PPPHLVSSHHELAVLFRTDHGISSGGF 407
Query: 1200 ELHFSSF 1206
+ +F
Sbjct: 408 SATYLAF 414
Score = 52.8 bits (125), Expect = 6e-06
Identities = 36/120 (30%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 2182 CGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRL---NLSL-LQTEPSGDFIT 2237
CGGN+T GT +P + Y C W I+VP GH + L N SL Q E D++
Sbjct: 301 CGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVE 360
Query: 2238 IWDGPQQTA-PRLGVFTRSMAKKTVQSSSNQVLLKFHRD-AATGGIFAIAFSAYPLTKCP 2295
+++ A LG F + + SS +++ + F D + G F+ + A+ T+ P
Sbjct: 361 VYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNATENP 420
>gi|62739188 complement factor H isoform b precursor [Homo sapiens]
Length = 449
Score = 120 bits (300), Expect = 3e-26
Identities = 117/456 (25%), Positives = 188/456 (41%), Gaps = 60/456 (13%)
Query: 2711 CLAGHCGTPEP-----IVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGK 2765
C+A C P I+ G + + Y +Y+C G+R +G + +C++ W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGE-WVAL 74
Query: 2766 TPF--CVLVSCGHPGSPPHSQMS---GDSYTVGAVVRYSCIGKRTLVGN-STRMCGLDGH 2819
P C CGHPG P + G+ + G Y+C L+G + R C DG
Sbjct: 75 NPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG- 133
Query: 2820 WTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDP------GTVMRFSCEAGHVLRGSSER 2873
WT +P C V C P +G + + +P G +RF C +G+ + G E
Sbjct: 134 WTNDIPICE---VVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEM 190
Query: 2874 TCQANGSWSGSQPECGVISCGNP----GTPSNARVVFSDGLVFSSSIVYECREGYYATGL 2929
C +G WS +P+C ISC +P G+P + ++++ + F Y+C GY +
Sbjct: 191 HCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQ----YKCNMGYEYSER 246
Query: 2930 LSRHCSVNGTWTGSDPECLVINCGDPGIPANG----LRLGNDFRYNKTVTYQCVPGYMME 2985
C+ +G W P C +C +P IP NG LR+ + R +TYQC G+
Sbjct: 247 GDAVCTESG-WRPL-PSCEEKSCDNPYIP-NGDYSPLRIKH--RTGDEITYQCRNGF-YP 300
Query: 2986 SHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGS------DFMWGSSVTYACL 3039
+ R + CT T P C C P + G + G +Y C
Sbjct: 301 ATRGNTAKCTS--TGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCD 358
Query: 3040 EGYQLSLPAVFT---CEGNGSWTGELP---QCFPVFCGDPGVPSRGRREDRGFSYRSSVS 3093
E ++ + + C +G W+ +P +C+ + + + GR+ F S+
Sbjct: 359 EHFETPSGSYWDHIHCTQDG-WSPAVPCLRKCYFPYLENGYNQNHGRK----FVQGKSID 413
Query: 3094 FSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLT 3129
+CHP L + + WS T P CI + T
Sbjct: 414 VACHPGYALPKAQTTVTCMENGWSPT-PRCIRVSFT 448
Score = 105 bits (263), Expect = 6e-22
Identities = 112/420 (26%), Positives = 157/420 (37%), Gaps = 40/420 (9%)
Query: 2786 SGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLP--HCSGTSVGVCGDPGIPAH 2843
S +Y G Y C +GN +C G W P C G GD
Sbjct: 38 SDQTYPEGTQAIYKCRPGYRSLGNVIMVCR-KGEWVALNPLRKCQKRPCGHPGDTPFGTF 96
Query: 2844 GIRLGDSFDPGTVMRFSCEAGHVLRGS-SERTCQANGSWSGSQPECGVISCGNPGTPSNA 2902
+ G+ F+ G ++C G+ L G + R C +G W+ P C V+ C P N
Sbjct: 97 TLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAPENG 155
Query: 2903 RVVFSD-----GLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGI 2957
++V S F ++ + C GY G HCS +G W+ P+C+ I+C P +
Sbjct: 156 KIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDV 215
Query: 2958 PANGLRLGNDFRY--NKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPP 3015
NG + Y N+ Y+C GY +V CT+ W P C+ C P
Sbjct: 216 -INGSPISQKIIYKENERFQYKCNMGYEYSERGDAV--CTESG-WRPL-PSCEEKSCDNP 270
Query: 3016 PLIPNGKV--VGSDFMWGSSVTYACLEG-YQLSLPAVFTCEGNGSWTGELPQCFPVFCGD 3072
IPNG + G +TY C G Y + C G W P+C C
Sbjct: 271 -YIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG-WI-PAPRCTLKPCDY 327
Query: 3073 PGVPSRG------RREDRGFSYRSSVSFSCHPPLVLVGSP---RRFCQSDGTWSGTQPSC 3123
P + G RR + S+ C C DG WS P
Sbjct: 328 PDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVPC- 385
Query: 3124 IDPTLTTCADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLL-QGSTTRTCLPNLTWSGTP 3182
L C P + QN+ + + G ++ C GY L + TT TC+ N WS TP
Sbjct: 386 ----LRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMEN-GWSPTP 440
Score = 93.2 bits (230), Expect = 4e-18
Identities = 116/423 (27%), Positives = 162/423 (38%), Gaps = 57/423 (13%)
Query: 2493 FGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPL--CQALSCGLPEAPKNG---MVFGKEY 2547
+ C GYR +G+ + +C + W PL CQ CG P G + G +
Sbjct: 50 YKCRPGYRSLGNVIMVCRKGE-----WVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVF 104
Query: 2548 TVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVP----PQCVPVTCPD---VSSIS 2600
G KA+Y+C+EGY L G EC DT W+N ++P +C+PVT P+ + S +
Sbjct: 105 EYGVKAVYTCNEGYQL-LGEINYREC-DTDGWTN-DIPICEVVKCLPVTAPENGKIVSSA 161
Query: 2601 VEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGE 2660
+E R +Y F + +C+ GY G + C +G WS P C ISC +
Sbjct: 162 MEPDR-------EYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWS--KEKPKCVEISC-K 211
Query: 2661 LPIPPNGHRIGTLSVYGATAIF--SCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGT 2718
P NG I +Y F CN GY C +G W C C
Sbjct: 212 SPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WRPLP-SCEEKSCDN 269
Query: 2719 PEPIVNGHINGENYSYR--GSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGH 2776
P I NG + +R + YQC GF W P C L C +
Sbjct: 270 PY-IPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWI-PAPRCTLKPCDY 327
Query: 2777 P----GSPPHSQMSGDSY--TVGAVVRYSCIGKRTLVGNS---TRMCGLDGHWTGSLPHC 2827
P G H M + VG Y C S C DG W+ ++P
Sbjct: 328 PDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVP-- 384
Query: 2828 SGTSVGVCGDPGIP-AHGIRLGDSFDPGTVMRFSCEAGHVL-RGSSERTCQANGSWSGSQ 2885
+ C P + + G F G + +C G+ L + + TC NG WS +
Sbjct: 385 ---CLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMENG-WSPT- 439
Query: 2886 PEC 2888
P C
Sbjct: 440 PRC 442
Score = 80.9 bits (198), Expect = 2e-14
Identities = 72/303 (23%), Positives = 117/303 (38%), Gaps = 40/303 (13%)
Query: 2518 LWSEAIPLCQALSCG-LPEAPKNGMVFG----KEYTVGTKAMYSCSEGYHLQAGAEATAE 2572
LW+ +C A C LP ++ G + Y GT+A+Y C GY
Sbjct: 12 LWA----ICVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCR 67
Query: 2573 CLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTG 2632
G W N +C C G + L +++ + + C+ GY G
Sbjct: 68 ---KGEWVALNPLRKCQKRPCGHPGD--TPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLG 122
Query: 2633 QRVIR-CQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSV------YGATAIFSCN 2685
+ R C +G W+ + P C ++ C + P NG + + +G F CN
Sbjct: 123 EINYRECDTDG-WT--NDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCN 179
Query: 2686 SGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGS--VVYQCN 2743
SGY + G C +G WS + +C+ C +P+ ++NG + Y+ + Y+CN
Sbjct: 180 SGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPD-VINGSPISQKIIYKENERFQYKCN 238
Query: 2744 AGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGD------SYTVGAVVR 2797
G+ +C + W P C SC +P P +GD + G +
Sbjct: 239 MGYEYSERGDAVCTES-GWR-PLPSCEEKSCDNPYIP-----NGDYSPLRIKHRTGDEIT 291
Query: 2798 YSC 2800
Y C
Sbjct: 292 YQC 294
Score = 63.2 bits (152), Expect = 4e-09
Identities = 55/232 (23%), Positives = 82/232 (35%), Gaps = 21/232 (9%)
Query: 3006 VCKALMCKPPPLIPNGKVVGSD-----FMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTG 3060
+C A C P N +++ + G+ Y C GY+ + C G W
Sbjct: 15 ICVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCR-KGEWVA 73
Query: 3061 ELP--QCFPVFCGDPGVPSRGRREDRG---FSYRSSVSFSCHPPLVLVGSPR-RFCQSDG 3114
P +C CG PG G G F Y ++C+ L+G R C +DG
Sbjct: 74 LNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG 133
Query: 3115 TWSGTQPSCIDPTLTTCADPGVPQFG-----IQNNSQGYQVGSTVLFRCQKGYLLQGSTT 3169
W+ P C + C P+ G + Y G V F C GY ++G
Sbjct: 134 -WTNDIPIC---EVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEE 189
Query: 3170 RTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGF 3221
C + WS P CV C+ P+ + + + Y C G+
Sbjct: 190 MHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGY 241
Score = 53.9 bits (128), Expect = 3e-06
Identities = 38/130 (29%), Positives = 58/130 (44%), Gaps = 15/130 (11%)
Query: 3144 NSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPP--DCVPHHCRQP-ETP--TH 3198
+ Q Y G+ +++C+ GY G+ C W P C C P +TP T
Sbjct: 38 SDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKG-EWVALNPLRKCQKRPCGHPGDTPFGTF 96
Query: 3199 ANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVR-------PS 3251
G ++ G +Y+C EG+ L G +R C DG WT PIC V+ +
Sbjct: 97 TLTGG-NVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAPEN 154
Query: 3252 GRPINTAREP 3261
G+ +++A EP
Sbjct: 155 GKIVSSAMEP 164
Score = 52.4 bits (124), Expect = 8e-06
Identities = 43/199 (21%), Positives = 75/199 (37%), Gaps = 16/199 (8%)
Query: 3079 GRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQP--SCIDPTLTTCADPGV 3136
G D+ + + + C P +G+ C+ G W P C C PG
Sbjct: 35 GSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRK-GEWVALNPLRKC---QKRPCGHPGD 90
Query: 3137 PQFGIQNNSQG--YQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPE 3194
FG + G ++ G ++ C +GY L G W+ P C C
Sbjct: 91 TPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTNDIPICEVVKCLPVT 150
Query: 3195 TPTHANVGALDLPS-----MGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVR 3249
P + + + + G + + C G+ ++G E C DG W+ + P C+E+
Sbjct: 151 APENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMH-CSDDGFWSKEKPKCVEI- 208
Query: 3250 PSGRPINTAREPPLTQALI 3268
S + + P++Q +I
Sbjct: 209 -SCKSPDVINGSPISQKII 226
Score = 52.4 bits (124), Expect = 8e-06
Identities = 81/332 (24%), Positives = 127/332 (38%), Gaps = 57/332 (17%)
Query: 2468 CSLPRAPLHGFILGQTSTQPGGSIHFG------CNAGYRLVGHSMAICTRHPQGYHLWSE 2521
C AP +G I+ ++ +P HFG CN+GY++ G C+ G+ WS+
Sbjct: 146 CLPVTAPENGKIVS-SAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCS--DDGF--WSK 200
Query: 2522 AIPLCQALSCGLPEAPKNGMVFGK-EYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWS 2580
P C +SC P+ + K Y + Y C+ GY +A C ++G W
Sbjct: 201 EKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAV--CTESG-W- 256
Query: 2581 NRNVPPQCVPVTCP-------DVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYY-YTG 2632
P C +C D S + ++H R E YQ C G+Y T
Sbjct: 257 --RPLPSCEEKSCDNPYIPNGDYSPLRIKH---RTGDEITYQ--------CRNGFYPATR 303
Query: 2633 QRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNG-HRIGTLSVYGATAI-----FSCNS 2686
+C + G W P C + C I G + Y A+ + C+
Sbjct: 304 GNTAKCTSTG-WI---PAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDE 359
Query: 2687 GYTLVGSRVRE---CMANGLWSGSEVRCLAGHCGTPEPIVNGH--INGENYSYRGSVVYQ 2741
+ + C +G WS + V CL C P + NG+ +G + S+
Sbjct: 360 HFETPSGSYWDHIHCTQDG-WSPA-VPCLR-KCYFPY-LENGYNQNHGRKFVQGKSIDVA 415
Query: 2742 CNAGFRLIGMSVRICQQDHHWSGKTPFCVLVS 2773
C+ G+ L + ++ WS TP C+ VS
Sbjct: 416 CHPGYALPKAQTTVTCMENGWS-PTPRCIRVS 446
Score = 42.4 bits (98), Expect = 0.008
Identities = 67/322 (20%), Positives = 124/322 (38%), Gaps = 38/322 (11%)
Query: 2291 LTKCPPPTILPNAEVVTE----NEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEG 2346
+ KC P T N ++V+ + E++ G VR+ C G+ + G+E + C + E
Sbjct: 143 VVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEK 202
Query: 2347 PPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEK 2406
P + E+ C + +++ S I + +FQ + Y S + +E
Sbjct: 203 PKCV-EISCKSPDVINGSP--ISQKIIYKENERFQ-----YKCNMGYEYSERGDAVCTES 254
Query: 2407 QYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYS-- 2464
+ + S +P + +G+YS I + + + + + +G + +
Sbjct: 255 GWRPLPSCEEKSCDNPYIP--NGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTST 312
Query: 2465 ----APYCSLPRAPL----HGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGY 2516
AP C+L HG + + +P + G Y H +
Sbjct: 313 GWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHI 372
Query: 2517 HL----WSEAIPLCQALSCGLPEAPKNG--MVFGKEYTVGTKAMYSCSEGYHLQAGAEAT 2570
H WS A+P + C P +NG G+++ G +C GY L A+ T
Sbjct: 373 HCTQDGWSPAVPCLR--KCYFPYL-ENGYNQNHGRKFVQGKSIDVACHPGYALPK-AQTT 428
Query: 2571 AECLDTGLWSNRNVPPQCVPVT 2592
C++ G WS P+C+ V+
Sbjct: 429 VTCMENG-WS---PTPRCIRVS 446
Score = 41.2 bits (95), Expect = 0.018
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 1727 VPRTSATQCSSVPEPRYGKRLGS------DFSVGAIVRFECNSGYALQGSPEIECLPVPG 1780
+P +C V P GK + S ++ G VRF CNSGY ++G E+ C
Sbjct: 138 IPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHC----S 193
Query: 1781 ALAQWNVSAPTCV 1793
W+ P CV
Sbjct: 194 DDGFWSKEKPKCV 206
Score = 39.7 bits (91), Expect = 0.053
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 13/78 (16%)
Query: 2139 YNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWD--HPLPKCEV-PCG-------GNITS 2188
Y G ++C PGY+ G+ ++ C+ G W +PL KC+ PCG G T
Sbjct: 42 YPEGTQAIYKCRPGYRSLGNVIMVCRKG---EWVALNPLRKCQKRPCGHPGDTPFGTFTL 98
Query: 2189 SNGTVYSPGFPSPYSSSQ 2206
+ G V+ G + Y+ ++
Sbjct: 99 TGGNVFEYGVKAVYTCNE 116
Score = 39.7 bits (91), Expect = 0.053
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 14/77 (18%)
Query: 349 PERGKRLGS------DFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRA 402
PE GK + S ++ G +V+F CN GY ++G + + C D F WS +P C
Sbjct: 152 PENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCS--DDGF--WSKEKPKCVE 207
Query: 403 RMCDAHLRGPSGIITSP 419
C + P I SP
Sbjct: 208 ISC----KSPDVINGSP 220
Score = 38.1 bits (87), Expect = 0.15
Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 6/60 (10%)
Query: 867 CLDPGIPVNGQ------RHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSC 920
CL P NG+ +++ G V F C+SGY + E + C + WS+ P C
Sbjct: 146 CLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKC 205
Score = 37.4 bits (85), Expect = 0.26
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 9/68 (13%)
Query: 1207 ELIKCEDPGTPKFGYKVHD------EGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTW 1260
E++KC P+ G V E HF G +V F C+ GY + G EE+ C + W
Sbjct: 142 EVVKCLPVTAPENGKIVSSAMEPDREYHF-GQAVRFVCNSGYKIEGDEEMHC--SDDGFW 198
Query: 1261 DRPLPTCV 1268
+ P CV
Sbjct: 199 SKEKPKCV 206
Score = 37.4 bits (85), Expect = 0.26
Identities = 14/43 (32%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 537 FHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCV-FSC 578
+H G ++F C +++ G + + C + WS +KP CV SC
Sbjct: 168 YHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISC 210
Score = 33.9 bits (76), Expect = 2.9
Identities = 31/127 (24%), Positives = 53/127 (41%), Gaps = 16/127 (12%)
Query: 976 DYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYD 1035
DY I G + + +R R P++ G Y ++ F + ++ + T +
Sbjct: 326 DYPDIKHGGLYHENMR-----RPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWS 380
Query: 1036 -----LEPCEEPEVP-AYSIRKGLQFGVGDTLTFSCFPGYRL-EGTARITCLGGRRRLWS 1088
L C P + Y+ G +F G ++ +C PGY L + +TC+ W
Sbjct: 381 PAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCM---ENGW- 436
Query: 1089 SPLPRCV 1095
SP PRC+
Sbjct: 437 SPTPRCI 443
Score = 33.1 bits (74), Expect = 5.0
Identities = 18/77 (23%), Positives = 29/77 (37%), Gaps = 9/77 (11%)
Query: 1372 GFAIQFSVSTATSCNDPGIPQNGSRSGDSWEA------GDSTVFQCDPGYALQGSAEISC 1425
G+ + C P+NG + E G + F C+ GY ++G E+ C
Sbjct: 133 GWTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHC 192
Query: 1426 VKIENRFFWQPSPPTCI 1442
+ FW P C+
Sbjct: 193 ---SDDGFWSKEKPKCV 206
Score = 32.3 bits (72), Expect = 8.4
Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 13/82 (15%)
Query: 2109 WDLD-PGCEAYELQECPDPEPFANGIVRGAG------YNVGQSVTFECLPGYQLTGHPVL 2161
W D P CE + PE NG + + Y+ GQ+V F C GY++ G +
Sbjct: 134 WTNDIPICEVVKCLPVTAPE---NGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEM 190
Query: 2162 TCQHGTNRNWDHPLPKC-EVPC 2182
C + W PKC E+ C
Sbjct: 191 HC--SDDGFWSKEKPKCVEISC 210
Score = 32.3 bits (72), Expect = 8.4
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 10/64 (15%)
Query: 1558 CFDPGSIKNGTRVGSDLK------LGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNP 1611
C + +NG V S ++ G +V + C+ GY++EG + C DG W+
Sbjct: 146 CLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHC--SDDG--FWSKE 201
Query: 1612 RPVC 1615
+P C
Sbjct: 202 KPKC 205
>gi|110611237 coagulation factor XIII B subunit precursor [Homo
sapiens]
Length = 661
Score = 112 bits (280), Expect = 6e-24
Identities = 151/577 (26%), Positives = 233/577 (40%), Gaps = 76/577 (13%)
Query: 2531 CGLPEAPKNGMVFGKEYT---------VGTKAMYSCSEGYHLQAGAEATAECLDTGLWSN 2581
CG P +NG + YT + K + C GY ++G + T WS
Sbjct: 25 CGFPHV-ENGRIAQYYYTFKSFYFPMSIDKKLSFFCLAGYTTESGRQEEQTTCTTEGWSP 83
Query: 2582 RNVPPQCVP-VTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTG---QRVIR 2637
P+C T PD+S+ + + Y+ Q + C GY TG + V++
Sbjct: 84 E---PRCFKKCTKPDLSNGYISD------VKLLYKIQENMRYGCASGYKTTGGKDEEVVQ 134
Query: 2638 CQANGKWSLGDSTPTCRIISCGELPIPP---NGHRIGTLSVYGAT--AIFSCNSGYTLVG 2692
C ++G WS S PTCR E + P NG+ T + + C +GY G
Sbjct: 135 CLSDG-WS---SQPTCR--KEHETCLAPELYNGNYSTTQKTFKVKDKVQYECATGYYTAG 188
Query: 2693 SRVRE---CMANGLWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSVVYQ--CNAGFR 2747
+ E C+ G WS + +C C + I NG+ + +Y V Q C+ +
Sbjct: 189 GKKTEEVECLTYG-WSLTP-KCTKLKCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYY 246
Query: 2748 LIGMSVRICQQDHHWSGKTPFCV--LVSCGHPGSPPHSQMSGDS--YTVGAVVRYSCIGK 2803
L G + C + W ++P C C P P +S++ S Y G +V C
Sbjct: 247 LSGSDLIQCY-NFGWYPESPVCEGRRNRCPPPPLPINSKIQTHSTTYRHGEIVHIECELN 305
Query: 2804 RTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDS--FDPGTVMRFSC 2861
+ G++ C DG WT G C +P +G S + G + ++C
Sbjct: 306 FEIHGSAEIRCE-DGKWTEPPKCIEGQEKVACEEPPFIENGAANLHSKIYYNGDKVTYAC 364
Query: 2862 EAGHVLRGSSERTCQANGSWSGSQPEC--GVISCGNPGTPSNARVVFSDGLVFS----SS 2915
++G++L GS+E TC G W+ PEC +C +P N V +DG++ S SS
Sbjct: 365 KSGYLLHGSNEITCN-RGKWT-LPPECVENNENCKHPPVVMNGAV--ADGILASYATGSS 420
Query: 2916 IVYECREGYYATGLLSRHCSVNGTWTGSDPECL-VINCGDPGIPANGLRLGNDFR----Y 2970
+ Y C E Y G C G W+ S P CL + N + + + +
Sbjct: 421 VEYRCNEYYLLRGSKISRCE-QGKWS-SPPVCLEPCTVNVDYMNRNNIEMKWKYEGKVLH 478
Query: 2971 NKTVTYQCVPGY-MMESHRVSVLSCTKDRTWNGTKPVCKAL----MCKPPPLIPNGKVVG 3025
+ + C GY + +S LS +R P+C MC PPLI +G ++
Sbjct: 479 GDLIDFVCKQGYDLSPLTPLSELSVQCNR-GEVKYPLCTRKESKGMCTSPPLIKHGVIIS 537
Query: 3026 S---DFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWT 3059
S + GSSV Y C + + L C +G WT
Sbjct: 538 STVDTYENGSSVEYRCFDHHFLEGSREAYCL-DGMWT 573
Score = 104 bits (260), Expect = 1e-21
Identities = 119/416 (28%), Positives = 170/416 (40%), Gaps = 43/416 (10%)
Query: 2857 MRFSCEAGHVL---RGSSERTCQANGSWSGSQPECGVISCGNP----GTPSNARVVFSDG 2909
+ F C AG+ R + TC G WS +P C C P G S+ ++++
Sbjct: 55 LSFFCLAGYTTESGRQEEQTTCTTEG-WS-PEPRC-FKKCTKPDLSNGYISDVKLLYK-- 109
Query: 2910 LVFSSSIVYECREGYYATGLLSRH---CSVNGTWTGSDPECLVIN--CGDPGI-PANGLR 2963
++ Y C GY TG C +G W+ S P C + C P + N
Sbjct: 110 --IQENMRYGCASGYKTTGGKDEEVVQCLSDG-WS-SQPTCRKEHETCLAPELYNGNYST 165
Query: 2964 LGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKV 3023
F+ V Y+C GY + + W+ T P C L C LI NG
Sbjct: 166 TQKTFKVKDKVQYECATGYYTAGGKKTEEVECLTYGWSLT-PKCTKLKCSSLRLIENGYF 224
Query: 3024 --VGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVF--CGDPGVPSRG 3079
V + G V + C E Y LS + C G W E P C C P +P
Sbjct: 225 HPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFG-WYPESPVCEGRRNRCPPPPLPINS 283
Query: 3080 RREDRGFSYRSS--VSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCID-PTLTTCADPGV 3136
+ + +YR V C + GS C+ DG W+ P CI+ C +P
Sbjct: 284 KIQTHSTTYRHGEIVHIECELNFEIHGSAEIRCE-DGKWT-EPPKCIEGQEKVACEEPPF 341
Query: 3137 PQFGIQN-NSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPH--HCRQP 3193
+ G N +S+ Y G V + C+ GYLL GS TC W+ PP+CV + +C+ P
Sbjct: 342 IENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNRG-KWT-LPPECVENNENCKHP 399
Query: 3194 ETPTHANV--GALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLE 3247
+ V G L + G ++ Y C E + L+G R C+ G W+ PP+CLE
Sbjct: 400 PVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISR-CE-QGKWS-SPPVCLE 452
Score = 95.5 bits (236), Expect = 8e-19
Identities = 142/548 (25%), Positives = 213/548 (38%), Gaps = 68/548 (12%)
Query: 2682 FSCNSGYTLVGSRVRE---CMANGLWSGSEVRCLAGHCGTPEPIVNGHINGEN--YSYRG 2736
F C +GYT R E C G WS E RC C P+ + NG+I+ Y +
Sbjct: 57 FFCLAGYTTESGRQEEQTTCTTEG-WS-PEPRCFK-KCTKPD-LSNGYISDVKLLYKIQE 112
Query: 2737 SVVYQCNAGFRLIG---MSVRICQQDHHWSGKTPFC------VLVSCGHPGSPPHSQMSG 2787
++ Y C +G++ G V C D WS + P C L + G+ +Q +
Sbjct: 113 NMRYGCASGYKTTGGKDEEVVQCLSDG-WSSQ-PTCRKEHETCLAPELYNGNYSTTQKT- 169
Query: 2788 DSYTVGAVVRYSCI-GKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGI- 2845
+ V V+Y C G T G T + P C+ C + +G
Sbjct: 170 --FKVKDKVQYECATGYYTAGGKKTEEVECLTYGWSLTPKCTKLK---CSSLRLIENGYF 224
Query: 2846 -RLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVIS--CGNPGTPSNA 2902
+ +++ G V++F C + L GS C N W P C C P P N+
Sbjct: 225 HPVKQTYEEGDVVQFFCHENYYLSGSDLIQCY-NFGWYPESPVCEGRRNRCPPPPLPINS 283
Query: 2903 RVVFSDGLVFSSSIVY-ECREGYYATGLLSRHCSVNGTWTGSDPECLV----INCGDPGI 2957
++ IV+ EC + G C +G WT P+C+ + C +P
Sbjct: 284 KIQTHSTTYRHGEIVHIECELNFEIHGSAEIRCE-DGKWT-EPPKCIEGQEKVACEEPPF 341
Query: 2958 PANGL-RLGNDFRYN-KTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPP 3015
NG L + YN VTY C GY++ H + ++C + + + V CK P
Sbjct: 342 IENGAANLHSKIYYNGDKVTYACKSGYLL--HGSNEITCNRGKWTLPPECVENNENCKHP 399
Query: 3016 PLIPNGKVVG---SDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGD 3072
P++ NG V + + GSSV Y C E Y L + CE G W+ P C +
Sbjct: 400 PVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCE-QGKWSSP-PVCLEPCTVN 457
Query: 3073 PGVPSRGRREDRGFSYRSSV------SFSCHP-----PLVLVGSPRRFCQSDGTWSGTQP 3121
+R E + + Y V F C PL + C P
Sbjct: 458 VDYMNRNNIEMK-WKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSVQCNRGEV---KYP 513
Query: 3122 SCI-DPTLTTCADPGVPQFG--IQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTW 3178
C + C P + + G I + Y+ GS+V +RC + L+GS CL + W
Sbjct: 514 LCTRKESKGMCTSPPLIKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYCLDGM-W 572
Query: 3179 SGTPPDCV 3186
+ TPP C+
Sbjct: 573 T-TPPLCL 579
Score = 47.4 bits (111), Expect = 3e-04
Identities = 59/267 (22%), Positives = 107/267 (40%), Gaps = 44/267 (16%)
Query: 1207 ELIKCEDPGTPKFGY-KVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLP 1265
E + CE+P + G +H + ++ G V+++C GY L GS E+ C G+ W P P
Sbjct: 332 EKVACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNRGK---WTLP-P 387
Query: 1266 TCVAECGG------TVRGEVSGQVL-SPGYPAPYEHNLNCIWTI------EAEAG----- 1307
CV + G V+ +L S + E+ N + + E G
Sbjct: 388 ECVENNENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCEQGKWSSP 447
Query: 1308 ------CTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQ 1361
CT+ + ++ + E+ W E VL +L + + + + +
Sbjct: 448 PVCLEPCTVNVDYMNRNNIEMK-----W--KYEGKVLHGDLIDFVCKQGYDLSPLTPLSE 500
Query: 1362 FSTDFFTSKQGFAIQFSVSTATSCNDPGIPQNG---SRSGDSWEAGDSTVFQCDPGYALQ 1418
S + + + + C P + ++G S + D++E G S ++C + L+
Sbjct: 501 LSVQCNRGEVKYPLCTRKESKGMCTSPPLIKHGVIISSTVDTYENGSSVEYRCFDHHFLE 560
Query: 1419 GSAEISCVKIENRFFWQPSPPTCIAPC 1445
GS E C+ W +PP C+ PC
Sbjct: 561 GSREAYCLD----GMW-TTPPLCLEPC 582
Score = 45.4 bits (106), Expect = 0.001
Identities = 58/249 (23%), Positives = 89/249 (35%), Gaps = 64/249 (25%)
Query: 1379 VSTATSCNDPGIPQNGSRSGD---SWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQ 1435
V +C P + NG+ + S+ G S ++C+ Y L+GS C + + W
Sbjct: 390 VENNENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCEQGK----WS 445
Query: 1436 PSPPTCIAPC--GGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLE 1493
SPP C+ PC D + + + Y G D F +
Sbjct: 446 -SPPVCLEPCTVNVDYMNRNNIEMKWKYEGKVLHGDLID-----------------FVCK 487
Query: 1494 PGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTEN 1553
GYD L+PL S+L + L R ++
Sbjct: 488 QGYDL-------SPLTPL------SELSVQCNRGEVKYPLCTRKES-------------- 520
Query: 1554 PRESCFDPGSIKNGTRVGSDLKL---GSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNN 1610
+ C P IK+G + S + GSSV Y C + +EG+ C+ G +W
Sbjct: 521 -KGMCTSPPLIKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYCLDG-----MWTT 574
Query: 1611 PRPVCTAPC 1619
P P+C PC
Sbjct: 575 P-PLCLEPC 582
Score = 44.7 bits (104), Expect = 0.002
Identities = 52/235 (22%), Positives = 86/235 (36%), Gaps = 64/235 (27%)
Query: 1749 SDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERRGTIL 1808
+ ++ G+ V + CN Y L+GS C +W+ S P C+ PC N+
Sbjct: 413 ASYATGSSVEYRCNEYYLLRGSKISRC-----EQGKWS-SPPVCLEPCTVNVDYMN---- 462
Query: 1809 SPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSFSG 1868
N++ WK EG + ++ FV +Q +D + +T L
Sbjct: 463 --------RNNIEMKWKY---EGKVLHGDLIDFVCKQGYDL--------SPLTPL----- 498
Query: 1869 TTVPALLNSTSNQLYLHFYSDISVSAAGFHLEY----KTVGLSSCPEPAVPSNGV---KT 1921
S++SV ++Y + C P + +GV T
Sbjct: 499 -------------------SELSVQCNRGEVKYPLCTRKESKGMCTSPPLIKHGVIISST 539
Query: 1922 GERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEME 1976
+ Y V ++C + L+G C+ G W PPLC+ C + EME
Sbjct: 540 VDTYENGSSVEYRCFDHHFLEGSREAYCLDG---MWT-TPPLCLEPCTLSFTEME 590
Score = 44.3 bits (103), Expect = 0.002
Identities = 88/428 (20%), Positives = 157/428 (36%), Gaps = 81/428 (18%)
Query: 2293 KCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTC-KLGTYLQFEGPPPIC 2351
KC ++ N + + GD+V++ C + L G++++ C G Y + P+C
Sbjct: 212 KCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFGWYPE----SPVC 267
Query: 2352 EVH---CPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQY 2408
E CP L +S Q++ +Y + +V +E + N
Sbjct: 268 EGRRNRCPPPPLPINSK----IQTHSTTYRHGE----IVHIECELN-------------- 305
Query: 2409 DEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYC 2468
FEI S ++ G ++ P V P+
Sbjct: 306 --FEIHG-----SAEIRCEDGKWTEPPKCIEGQEKVACE----------------EPPFI 342
Query: 2469 SLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQA 2528
A LH I G + + C +GY L G + C R + L E + +
Sbjct: 343 ENGAANLHSKIYYN-----GDKVTYACKSGYLLHGSNEITCNRGK--WTLPPECVENNE- 394
Query: 2529 LSCGLPEAPKNGMVFG---KEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVP 2585
+C P NG V Y G+ Y C+E Y+L G++ + + G WS+ P
Sbjct: 395 -NCKHPPVVMNGAVADGILASYATGSSVEYRCNE-YYLLRGSKISR--CEQGKWSS---P 447
Query: 2586 PQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYT-----GQRVIRCQA 2640
P C+ +V ++ + + +E + + +C GY + + ++C
Sbjct: 448 PVCLEPCTVNVDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSVQCN- 506
Query: 2641 NGKWSLGDSTPTCRIISCGELPIPPNGHRI-GTLSVY--GATAIFSCNSGYTLVGSRVRE 2697
G+ T C P+ +G I T+ Y G++ + C + L GSR
Sbjct: 507 RGEVKYPLCTRKESKGMCTSPPLIKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAY 566
Query: 2698 CMANGLWS 2705
C+ +G+W+
Sbjct: 567 CL-DGMWT 573
Score = 42.4 bits (98), Expect = 0.008
Identities = 28/85 (32%), Positives = 33/85 (38%), Gaps = 8/85 (9%)
Query: 2109 WDLDPGCEAYELQECPDPEPFANGIVRG---AGYNVGQSVTFECLPGYQLTGHPVLTCQH 2165
W L P C + C P NG V A Y G SV + C Y L G + C+
Sbjct: 383 WTLPPECVENN-ENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCEQ 441
Query: 2166 GTNRNWDHPLPKCEVPCGGNITSSN 2190
G W P P C PC N+ N
Sbjct: 442 G---KWSSP-PVCLEPCTVNVDYMN 462
Score = 39.3 bits (90), Expect = 0.069
Identities = 52/213 (24%), Positives = 75/213 (35%), Gaps = 59/213 (27%)
Query: 886 GALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYP 945
G +V F C Y LS + ++C NF W P CE G P P
Sbjct: 234 GDVVQFFCHENYYLSGSDLIQCY-NFGWYPESPVCE--------GRRNRCPPPPLPI--- 281
Query: 946 NNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAG 1005
N+ T HG+ V + E + E+G +T+P + + G A
Sbjct: 282 NSKIQTHSTTYRHGEIVHIECE-LNFEIHGSAEIRCEDGKWTEPPKCIEGQEKVA----- 335
Query: 1006 LYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCEEP---EVPAYSIRKGLQFGVGDTLT 1062
CEEP E A ++ + + GD +T
Sbjct: 336 ---------------------------------CEEPPFIENGAANLHSKIYYN-GDKVT 361
Query: 1063 FSCFPGYRLEGTARITCLGGRRRLWSSPLPRCV 1095
++C GY L G+ ITC G+ W+ P P CV
Sbjct: 362 YACKSGYLLHGSNEITCNRGK---WTLP-PECV 390
Score = 38.9 bits (89), Expect = 0.090
Identities = 57/256 (22%), Positives = 92/256 (35%), Gaps = 70/256 (27%)
Query: 1556 ESCFDPGSIKNGTRVGSDLK---LGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPR 1612
E+C P + NG L GSSV Y C+ Y + G+ C G W++P
Sbjct: 394 ENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCEQGK-----WSSP- 447
Query: 1613 PVCTAPC--GGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALND 1670
PVC PC Y+ + + + Y G + + D T L++
Sbjct: 448 PVCLEPCTVNVDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPL-------TPLSE 500
Query: 1671 V-VEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPR 1729
+ V+ + G ++ PL T + +KG+
Sbjct: 501 LSVQCNRGEVKY----------------PLCTRKE------SKGM--------------- 523
Query: 1730 TSATQCSSVPEPRYGKRLGSD---FSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWN 1786
C+S P ++G + S + G+ V + C + L+GS E CL W
Sbjct: 524 -----CTSPPLIKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYCLD-----GMW- 572
Query: 1787 VSAPTCVVPCGGNLTE 1802
+ P C+ PC + TE
Sbjct: 573 TTPPLCLEPCTLSFTE 588
Score = 38.5 bits (88), Expect = 0.12
Identities = 64/286 (22%), Positives = 99/286 (34%), Gaps = 49/286 (17%)
Query: 1908 SCPEPAVPSNGVKT--GERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCI 1965
+C EP NG + Y D V++ C+ GY L G I+C G +W PP C+
Sbjct: 335 ACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNRG---KWTLPPE-CV 390
Query: 1966 ---AQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYI 2022
C M G + + G +Y + ++ ++Y
Sbjct: 391 ENNENCKHPPVVMNGAV-ADGILASYATGSSVEYRC--------------------NEYY 429
Query: 2023 EIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQI 2082
+R G++S P L Y ++N K +Y+ +
Sbjct: 430 LLRGSKISRCE-QGKWSS---PPVCLEPCTVNVDYM----NRNNIEMKWKYEGKVLHGDL 481
Query: 2083 SSFL--RGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQ-ECPDPEPFANGIVRGA-- 2137
F+ +G+DLS L S V + P C E + C P +G++ +
Sbjct: 482 IDFVCKQGYDLSPLTPL-SELSVQCNRGEVKYPLCTRKESKGMCTSPPLIKHGVIISSTV 540
Query: 2138 -GYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPC 2182
Y G SV + C + L G C G W P P C PC
Sbjct: 541 DTYENGSSVEYRCFDHHFLEGSREAYCLDGM---WTTP-PLCLEPC 582
Score = 36.6 bits (83), Expect = 0.45
Identities = 25/73 (34%), Positives = 30/73 (41%), Gaps = 7/73 (9%)
Query: 2109 WDLDPGC-EAYELQECPDPEPFANGI--VRGAGYNVGQSVTFECLPGYQLTGHPVLTCQH 2165
W P C E E C +P NG + Y G VT+ C GY L G +TC
Sbjct: 321 WTEPPKCIEGQEKVACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNR 380
Query: 2166 GTNRNWDHPLPKC 2178
G W P P+C
Sbjct: 381 G---KWTLP-PEC 389
Score = 35.4 bits (80), Expect = 1.00
Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 8/60 (13%)
Query: 139 CGNPGRLPNGIQQ--GSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
C P + NG + GDKV Y+C G+ L G +TC+ G W P P C
Sbjct: 336 CEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNRGK-----WTLP-PEC 389
Score = 34.7 bits (78), Expect = 1.7
Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 5/55 (9%)
Query: 1909 CPEPAVPSNG-VKT-GERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPP 1961
CP P +P N ++T Y ++V +CE + + G A I C G +W PP
Sbjct: 274 CPPPPLPINSKIQTHSTTYRHGEIVHIECELNFEIHGSAEIRCEDG---KWTEPP 325
Score = 32.7 bits (73), Expect = 6.5
Identities = 17/42 (40%), Positives = 18/42 (42%), Gaps = 5/42 (11%)
Query: 362 GSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRAR 403
G VQF C+E Y L GS I C W PVC R
Sbjct: 234 GDVVQFFCHENYYLSGSDLIQCYNF-----GWYPESPVCEGR 270
Score = 32.3 bits (72), Expect = 8.4
Identities = 20/63 (31%), Positives = 25/63 (39%), Gaps = 6/63 (9%)
Query: 1381 TATSCNDPGIPQNG--SRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSP 1438
T C+ + +NG ++E GD F C Y L GS I C F W P
Sbjct: 209 TKLKCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCY----NFGWYPES 264
Query: 1439 PTC 1441
P C
Sbjct: 265 PVC 267
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 161,119,041
Number of Sequences: 37866
Number of extensions: 8553335
Number of successful extensions: 32008
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 136
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 16327
Number of HSP's gapped (non-prelim): 6944
length of query: 3487
length of database: 18,247,518
effective HSP length: 121
effective length of query: 3366
effective length of database: 13,665,732
effective search space: 45998853912
effective search space used: 45998853912
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.