BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens] (863 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens] 1833 0.0 gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens] 1819 0.0 gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens] 1808 0.0 gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3 ... 796 0.0 gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1 ... 762 0.0 gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4 (p... 192 1e-48 gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5 (... 184 3e-46 gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6 [... 178 2e-44 gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7 [... 176 8e-44 gi|239755573 PREDICTED: similar to ectonucleotide pyrophosphatas... 73 1e-12 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 54 8e-07 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 54 8e-07 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 49 2e-05 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 49 2e-05 gi|88853069 vitronectin precursor [Homo sapiens] 42 0.003 gi|5174623 placental protein 11 precursor [Homo sapiens] 41 0.005 gi|38045917 phosphatidylinositol glycan anchor biosynthesis, cla... 40 0.007 gi|23397648 phosphatidylinositol glycan anchor biosynthesis, cla... 40 0.007 gi|4557733 latent transforming growth factor beta binding protei... 40 0.012 gi|169217819 PREDICTED: similar to hCG1793095 [Homo sapiens] 38 0.046 gi|239756564 PREDICTED: similar to hCG1793095 [Homo sapiens] 38 0.046 gi|187608744 zinc finger protein 9 isoform 5 [Homo sapiens] 38 0.046 gi|123702038 keratin associated protein 5-9 [Homo sapiens] 38 0.046 gi|209969800 RPE-spondin [Homo sapiens] 36 0.13 gi|146229331 arylsulfatase A isoform a precursor [Homo sapiens] 36 0.18 gi|146229329 arylsulfatase A isoform a precursor [Homo sapiens] 36 0.18 gi|146229327 arylsulfatase A isoform b [Homo sapiens] 36 0.18 gi|146229324 arylsulfatase A isoform a precursor [Homo sapiens] 36 0.18 gi|6005990 arylsulfatase A isoform a precursor [Homo sapiens] 36 0.18 gi|187608732 zinc finger protein 9 isoform 2 [Homo sapiens] 35 0.23 >gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens] Length = 863 Score = 1833 bits (4747), Expect = 0.0 Identities = 863/863 (100%), Positives = 863/863 (100%) Query: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK Sbjct: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60 Query: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC Sbjct: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120 Query: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK Sbjct: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180 Query: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA Sbjct: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240 Query: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER Sbjct: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300 Query: 301 PSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360 PSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH Sbjct: 301 PSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360 Query: 361 GMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQH 420 GMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQH Sbjct: 361 GMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQH 420 Query: 421 FKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNK 480 FKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNK Sbjct: 421 FKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNK 480 Query: 481 VNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTF 540 VNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTF Sbjct: 481 VNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTF 540 Query: 541 RPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEERHLLYG 600 RPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEERHLLYG Sbjct: 541 RPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEERHLLYG 600 Query: 601 RPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVS 660 RPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVS Sbjct: 601 RPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVS 660 Query: 661 PSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVL 720 PSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVL Sbjct: 661 PSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVL 720 Query: 721 VKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQ 780 VKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQ Sbjct: 721 VKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQ 780 Query: 781 PADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFR 840 PADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFR Sbjct: 781 PADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFR 840 Query: 841 KTSRSYPEILTLKTYLHTYESEI 863 KTSRSYPEILTLKTYLHTYESEI Sbjct: 841 KTSRSYPEILTLKTYLHTYESEI 863 >gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens] Length = 888 Score = 1819 bits (4711), Expect = 0.0 Identities = 863/888 (97%), Positives = 863/888 (97%), Gaps = 25/888 (2%) Query: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK Sbjct: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60 Query: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC Sbjct: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120 Query: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK Sbjct: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180 Query: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA Sbjct: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240 Query: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER Sbjct: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300 Query: 301 PSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360 PSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH Sbjct: 301 PSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360 Query: 361 GMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQH 420 GMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQH Sbjct: 361 GMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQH 420 Query: 421 FKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNK 480 FKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNK Sbjct: 421 FKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNK 480 Query: 481 VNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTF 540 VNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTF Sbjct: 481 VNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTF 540 Query: 541 RPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTE------- 593 RPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTE Sbjct: 541 RPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEAETRKFR 600 Query: 594 ------------------ERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYT 635 ERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYT Sbjct: 601 GSRNENKENINGNFEPRKERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYT 660 Query: 636 VSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYD 695 VSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYD Sbjct: 661 VSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYD 720 Query: 696 AFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQ 755 AFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQ Sbjct: 721 AFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQ 780 Query: 756 YVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKW 815 YVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKW Sbjct: 781 YVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKW 840 Query: 816 VEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI 863 VEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI Sbjct: 841 VEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI 888 >gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens] Length = 915 Score = 1808 bits (4684), Expect = 0.0 Identities = 863/915 (94%), Positives = 863/915 (94%), Gaps = 52/915 (5%) Query: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK Sbjct: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60 Query: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC Sbjct: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120 Query: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK Sbjct: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180 Query: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA Sbjct: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240 Query: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER Sbjct: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300 Query: 301 PSVYAFYSEQPDFSGHKYGPFGPE------------------------------------ 324 PSVYAFYSEQPDFSGHKYGPFGPE Sbjct: 301 PSVYAFYSEQPDFSGHKYGPFGPEESSYGSPFTPAKRPKRKVAPKRRQERPVAPPKKRRR 360 Query: 325 ----------------MTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCD 368 MTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCD Sbjct: 361 KIHRMDHYAAETRQDKMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCD 420 Query: 369 RTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQH 428 RTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQH Sbjct: 421 RTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQH 480 Query: 429 LPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVF 488 LPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVF Sbjct: 481 LPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVF 540 Query: 489 VGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEV 548 VGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEV Sbjct: 541 VGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEV 600 Query: 549 TRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEERHLLYGRPAVLYRT 608 TRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEERHLLYGRPAVLYRT Sbjct: 601 TRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEERHLLYGRPAVLYRT 660 Query: 609 RYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCL 668 RYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCL Sbjct: 661 RYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCL 720 Query: 669 AYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASER 728 AYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASER Sbjct: 721 AYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASER 780 Query: 729 NGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGP 788 NGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGP Sbjct: 781 NGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGP 840 Query: 789 LSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPE 848 LSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPE Sbjct: 841 LSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPE 900 Query: 849 ILTLKTYLHTYESEI 863 ILTLKTYLHTYESEI Sbjct: 901 ILTLKTYLHTYESEI 915 >gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3 [Homo sapiens] Length = 875 Score = 796 bits (2057), Expect = 0.0 Identities = 377/835 (45%), Positives = 541/835 (64%), Gaps = 39/835 (4%) Query: 57 GSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEEN 116 GSC+ +CF+ G +CRCD CK CC DF++ C+++ R W C K RCGE R E + Sbjct: 52 GSCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEAS 111 Query: 117 ACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRA 176 C CS+DCL R DCC +Y+ VC+GE+ W++++C+ + ++CP GF PP+I+FS+DGFRA Sbjct: 112 LCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRA 171 Query: 177 SYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDP 236 Y+ +MPNI KL++CG HS YMR +YPTKTFPN YT+ TGLYPESHGI+ N+MYD Sbjct: 172 EYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDV 231 Query: 237 VFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFW------------------SV 278 + F L +E+ N WW GQP+W+TA QG+KA T+FW + Sbjct: 232 NLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNG 291 Query: 279 VIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQ 338 +P E RI T+L+WL LP ERP Y Y E+PD SGH GP + L+ +D G Sbjct: 292 SVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGM 351 Query: 339 LMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFS 398 LM+GLKQ LH CVN+I + DHGM+ C++ E++++Y ++ + G RIR + Sbjct: 352 LMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIR---A 408 Query: 399 NNAKYD-----PKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWH 453 +N +D + I+ NL+C+KPDQHFKPYL LPKRLHYA N RI+ +HL V+++W Sbjct: 409 HNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQW- 467 Query: 454 VARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVM 513 L V K + C G+HG++N+ SM+ +F+ +G +FK KT+V PFENIE+YN+M Sbjct: 468 -----LAVRSKSNTNC-GGGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLM 521 Query: 514 CDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKV 573 CDLL ++PAPNNGTHGSLNHLL+ + P+ EEV++ + G L C C + Sbjct: 522 CDLLRIQPAPNNGTHGSLNHLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFC-PHL 580 Query: 574 EPKNKLDELNKRLHTK----GSTEERHLLYGRPAVLYR-TRYDILYHTDFESGYSEIFLM 628 + +L+++N+ L+ +T + +L +GRP VL + + +LYH ++ SG+ + M Sbjct: 581 QNSTQLEQVNQMLNLTQEEITATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRM 640 Query: 629 PLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSS 688 P+W+SYTV + + S +P + C+R DVRV PS SQ C Y DK +++GFL+PP + Sbjct: 641 PMWSSYTVPQLGDTSPLPPTVPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNR 700 Query: 689 SPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHD 748 + +++YDA + +N+VPMY F+++W+YF VL+ K+A+ERNGVNV+SGPIFDY+YDG D Sbjct: 701 TSDSQYDALITSNLVPMYEEFRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFD 760 Query: 749 TEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNS 808 D+I +++ + +P+PTHY+ ++TSC + + + C G L V FI+PHRP N ESC Sbjct: 761 APDEITKHLANTDVPIPTHYFVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPE 820 Query: 809 SEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI 863 + E+ WVEE H ARVRD+E LT LDF++ + EIL LKTYL T+E+ I Sbjct: 821 GKPEALWVEERFTAHIARVRDVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI 875 >gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1 [Homo sapiens] Length = 925 Score = 762 bits (1967), Expect = 0.0 Identities = 376/831 (45%), Positives = 518/831 (62%), Gaps = 39/831 (4%) Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117 SCKGRCFE +CRCD C +CC D+ E C++ W C K RCGE R + Sbjct: 107 SCKGRCFERTFG---NCRCDAACVELGNCCLDYQETCIEPEHIWTCNKFRCGEKRLTRSL 163 Query: 118 CHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRAS 177 C CS+DC +GDCC NY VC+GE WV++ CE I +CPAGF PP ++FS+DGFRA Sbjct: 164 CACSDDCKDKGDCCINYSSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAE 223 Query: 178 YMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPV 237 Y+ ++P I KL+ CGT++ MRPVYPTKTFPN Y++ TGLYPESHGI+ N MYDP Sbjct: 224 YLHTWGGLLPVISKLKKCGTYTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPK 283 Query: 238 FDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFW------------------SVV 279 +A+F L+ +EKFN W+ G+P+W+TA QG+K+GTFFW + Sbjct: 284 MNASFSLKSKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGS 343 Query: 280 IPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQL 339 +P E RIL +LQWL LP ERP Y Y E+PD SGH YGP E+ L+ +D +VG L Sbjct: 344 VPFEERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGML 403 Query: 340 MDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSN 399 MDGLK+L LHRC+N+I + DHGME +C + +L+ YL +V +I ++ G R+R Sbjct: 404 MDGLKELNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVP 463 Query: 400 NAKY--DPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARK 457 + Y + + I NL+C++P+QHFKPYLK LPKRLH+A + RIE + ++ +W +A Sbjct: 464 DKYYSFNYEGIARNLSCREPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQLALN 523 Query: 458 PLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLL 517 P + +K G G HG DN ++MQ +FVGYG FK+ + FENIE+YN+MCDLL Sbjct: 524 PSE--RKYCG----SGFHGSDNVFSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDLL 577 Query: 518 GLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEP-K 576 L PAPNNGTHGSLNHLL+ + P P+EV P +LGC+C+ + P + Sbjct: 578 NLTPAPNNGTHGSLNHLLKNPVYTPKHPKEV-HPLVQCPFTRNPRDNLGCSCNPSILPIE 636 Query: 577 NKLDELNKRLHTKGSTEERHLLYGRPAVLYR-TRYDILYHTDFESGYSEIFLMPLWTSYT 635 + + N + + + L YGRP VL + +L F SGYS+ LMPLWTSYT Sbjct: 637 DFQTQFNLTVAEEKIIKHETLPYGRPRVLQKENTICLLSQHQFMSGYSQDILMPLWTSYT 696 Query: 636 VSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKY- 694 V + S+ + ++C+ D R+ S C YKN+ ++SYGFL PP L+ + Y Sbjct: 697 VDRNDSFST--EDFSNCLYQDFRIPLSPVHKCSFYKNNTKVSYGFLSPPQLNKNSSGIYS 754 Query: 695 DAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIK 754 +A L TN+VPMY +F+ +W YF L++KYA ERNGVNV+SGP+FD+DYDG D+ + ++ Sbjct: 755 EALLTTNIVPMYQSFQVIWRYFHDTLLRKYAEERNGVNVVSGPVFDFDYDGRCDSLENLR 814 Query: 755 Q---YVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSED 811 Q + I +PTH++ ++TSC D +Q C+ L +FILPHR DN ESC + Sbjct: 815 QKRRVIRNQEILIPTHFFIVLTSCKDTSQTPLHCEN-LDTLAFILPHRTDNSESCVHGKH 873 Query: 812 ESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESE 862 +S WVEEL+ +H AR+ D+EH+T L F+++ +IL LKT+L T+ E Sbjct: 874 DSSWVEELLMLHRARITDVEHITGLSFYQQRKEPVSDILKLKTHLPTFSQE 924 >gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function) [Homo sapiens] Length = 453 Score = 192 bits (487), Expect = 1e-48 Identities = 130/394 (32%), Positives = 188/394 (47%), Gaps = 45/394 (11%) Query: 164 PPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYP 223 P L++ S DGFRA Y+K P+++ G +++ V+ TKTFPN Y++ TGLY Sbjct: 26 PKLLLVSFDGFRADYLKNYE--FPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYE 83 Query: 224 ESHGIVGNSMYDPVFDATFHLRGREKFNHRWWG-GQPLWITATKQGVKAG---------- 272 ESHGIV NSMYD V H + WW P+W+T Q ++ Sbjct: 84 ESHGIVANSMYDAVTKK--HFSDSNDKDPFWWNEAVPIWVTNQLQENRSSAAAMWPGTDV 141 Query: 273 -------TFF--WSVVIPHERRILTILQWLTLPDHERPSVYA-FYSEQPDFSGHKYGPFG 322 ++F ++ + E R+ I WL + P +A Y E+PD SGHKYGP Sbjct: 142 PIHDTISSYFMNYNSSVSFEERLNNITMWLN--NSNPPVTFATLYWEEPDASGHKYGPED 199 Query: 323 PE-MTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVD 381 E M+ L++ID ++G L+ LK L L +NVI DHGM + DR L + + + Sbjct: 200 KENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSY 259 Query: 382 DITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRI 441 + + I K + Y+ K H YLK+ +P R +Y +N RI Sbjct: 260 YTLIDLSPVAAILPKINRTEVYNK--------LKNCSPHMNVYLKEDIPNRFYYQHNDRI 311 Query: 442 EDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKV 501 + I L+ + W + V + S K GDHG+DN + SM +G F K Sbjct: 312 QPIILVADEGWTI------VLNESSQKL---GDHGYDNSLPSMHPFLAAHGPAFHKGYKH 362 Query: 502 PPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLL 535 +++Y +MC +LGLKP PNNGT G LL Sbjct: 363 STINIVDIYPMMCHILGLKPHPNNGTFGHTKCLL 396 >gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative function) [Homo sapiens] Length = 477 Score = 184 bits (467), Expect = 3e-46 Identities = 117/391 (29%), Positives = 188/391 (48%), Gaps = 38/391 (9%) Query: 166 LIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPES 225 +++ S DGFR Y+ K P+ + G H + V+ TKT+PN YTL TGL+ E+ Sbjct: 30 VLLVSFDGFRWDYLYKVPT--PHFHYIMKYGVHVKQVTNVFITKTYPNHYTLVTGLFAEN 87 Query: 226 HGIVGNSMYDPVFDATFHLRGREKFNHRWW-GGQPLWITATKQGVKAGTFFW-------- 276 HGIV N M+DP+ + +F L ++ ++W P+WIT + G +G W Sbjct: 88 HGIVANDMFDPIRNKSFSLDHMNIYDSKFWEEATPIWITNQRAGHTSGAAMWPGTDVKIH 147 Query: 277 ----------SVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMT 326 + + E R+ I++W T E ++ Y E PD GH GP P M Sbjct: 148 KRFPTHYMPYNESVSFEDRVAKIIEWFT--SKEPINLGLLYWEDPDDMGHHLGPDSPLMG 205 Query: 327 NPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLV 386 + +IDK +G L+ LK+ KL +N+I DHGM + +R L YL + D TL+ Sbjct: 206 PVISDIDKKLGYLIQMLKKAKLWNTLNLIITSDHGMTQCSEERLIELDQYL-DKDHYTLI 264 Query: 387 PGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHL 446 + + + K+D + LT P + Y K+ +P+R HY N RI+ I Sbjct: 265 DQS--PVAAILPKEGKFD--EVYEALTHAHP--NLTVYKKEDVPERWHYKYNSRIQPIIA 318 Query: 447 LVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFEN 506 + + WH+ + D F G+HG+DN + M +F+ +G F+ + Sbjct: 319 VADEGWHILQNKSD--------DFLLGNHGYDNALADMHPIFLAHGPAFRKNFSKEAMNS 370 Query: 507 IELYNVMCDLLGLKPAPNNGTHGSLNHLLRT 537 +LY ++C LL + P+NG+ ++ LL + Sbjct: 371 TDLYPLLCHLLNITAMPHNGSFWNVQDLLNS 401 >gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6 [Homo sapiens] Length = 440 Score = 178 bits (451), Expect = 2e-44 Identities = 115/414 (27%), Positives = 209/414 (50%), Gaps = 41/414 (9%) Query: 163 RPPLIIFSVDGFRASYMK-KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGL 221 R L++F +DGFR+ Y+ + + +P +++ S G Y+ P +P+ ++PN YTL TG Sbjct: 23 RRKLLVFLLDGFRSDYISDEALESLPGFKEIVSRGVKVDYLTPDFPSLSYPNYYTLMTGR 82 Query: 222 YPESHGIVGNSMYDPVFDATFHLR-GREKFNHRWWGG-QPLWITATKQGVKAGTFFWSVV 279 + E H ++GN M+DP + +F + ++ WW G +PLW+T TK K ++W Sbjct: 83 HCEVHQMIGNYMWDPTTNKSFDIGVNKDSLMPLWWNGSEPLWVTLTKAKRKVYMYYWPGC 142 Query: 280 IPHERRILTI-----LQWLTLPDH----------------ERPSVYAFYSEQPDFSGHKY 318 E IL + L++ +P R + A Y E+ D GH Y Sbjct: 143 ---EVEILGVRPTYCLEYKNVPTDINFANAVSDALDSFKSGRADLAAIYHERIDVEGHHY 199 Query: 319 GPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVT-CDRTEFLSNYL 377 GP P+ + L+ +D ++ + +++ L +NVI DHGM D+ D+ L+ Y+ Sbjct: 200 GPASPQRKDALKAVDTVLKYMTKWIQERGLQDRLNVIIFSDHGMTDIFWMDKVIELNKYI 259 Query: 378 TNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYAN 437 + ++D+ V G + S + K+ I L+ +H Y K+ +P R +Y Sbjct: 260 S-LNDLQQVKDR-GPVVSLWPAPGKHSE--IYNKLSTV---EHMTVYEKEAIPSRFYYKK 312 Query: 438 NRRIEDIHLLVERRWHVA--RKPLDVYKKPSGKC--FFQGDHGFDNKVNSMQTVFVGYGS 493 + + + L+ + W + R+ L + +G+ + +G HG+DN++ M+ +F+ +G Sbjct: 313 GKFVSPLTLVADEGWFITENREMLPFWMNSTGRREGWQRGWHGYDNELMDMRGIFLAFGP 372 Query: 494 TFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLL--RTNTFRPTMP 545 FK + P ++++YNVMC+++G+ P PNNG+ + +L R +T P P Sbjct: 373 DFKSNFRAAPIRSVDVYNVMCNVVGITPLPNNGSWSRVMCMLKGRASTAPPVWP 426 >gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7 [Homo sapiens] Length = 458 Score = 176 bits (446), Expect = 8e-44 Identities = 130/416 (31%), Positives = 197/416 (47%), Gaps = 67/416 (16%) Query: 166 LIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPES 225 L++ S DGFR +Y + PN++ + G + YM P + T T P +TL TG Y E+ Sbjct: 33 LLLVSFDGFRWNYDQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIEN 90 Query: 226 HGIVGNSMYDPV------FDATFHLRGREKFNHRWW--GGQPLWITATKQGVKAGTFFW- 276 HG+V N Y+ + AT ++ RWW G P+WITA +QG++AG+FF+ Sbjct: 91 HGVVHNMYYNTTSKVKLPYHATLGIQ-------RWWDNGSVPIWITAQRQGLRAGSFFYP 143 Query: 277 -------SVVIPHERR----------------ILTILQWLTLPDHERPSVYAFYSEQPDF 313 V + R+ I T++ W T D + + Y +PD Sbjct: 144 GGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLD---LVTLYFGEPDS 200 Query: 314 SGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDV---TCDRT 370 +GH+YGP PE +R++D+ VG L + + + L +N+I DHGM V D Sbjct: 201 TGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLV 260 Query: 371 EF--LSNYLTNVDDITLVP-GTLGRIRSKFSNNAK-YDPKAIIANLTCKKPDQHFKPYLK 426 EF N+ + L+ G G + K K YD L P H Y K Sbjct: 261 EFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDA------LKDAHPKLHV--YKK 312 Query: 427 QHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQT 486 + P+ HYANN R+ + L+ +V ++V F G+HGFDNK M+T Sbjct: 313 EAFPEAFHYANNPRVTPL-LMYSDLGYVIHGRINVQ-------FNNGEHGFDNKDMDMKT 364 Query: 487 VFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRP 542 +F G +F+ +V PFE++ +Y +MC LLG+ P N+G +L +L T + P Sbjct: 365 IFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPMLHTESALP 420 >gi|239755573 PREDICTED: similar to ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative function) [Homo sapiens] Length = 661 Score = 72.8 bits (177), Expect = 1e-12 Identities = 64/264 (24%), Positives = 103/264 (39%), Gaps = 36/264 (13%) Query: 288 TILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLK 347 T++ T D + Y QPD GH++ P ++++D+ + L+ ++ Sbjct: 269 TVMNCFTKEDFD---FVTLYYRQPDNVGHRFKPEAENRKLMIQQLDRTIWYLVGATEKHS 325 Query: 348 LHRCVNVIFVGDHGMEDVTCDRTE---FLSNYLTNVD----DITLVPGTLGRIRSKFSNN 400 L + VI DHGM V LSNY+ D DI G + Sbjct: 326 L-QSPQVIITXDHGMMTVKKRPNVNKIXLSNYIKFRDWVKFDIVGYGGFGLPLPKLGQEE 384 Query: 401 AKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLD 460 A Y K H Y K+ P+ H A + R+ I + + + Sbjct: 385 ALYQ--------ALKNAHPHLHIYKKEEFPEHFHLAKHDRVLPIVMYANSSYRYLDSSMR 436 Query: 461 VYKK----PSGK-------------CFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPP 503 + + P+ + CF +G HGFDN + M+T+F +G FK Sbjct: 437 TFNETRTFPTDQPDSLREQDARIIMCFNKGSHGFDNVLMDMKTIFRDFGPDFKKNGLAET 496 Query: 504 FENIELYNVMCDLLGLKPAPNNGT 527 F +I +Y +C LLG+ P +NG+ Sbjct: 497 FNSIHIYPFVCKLLGVXPQTHNGS 520 Score = 40.4 bits (93), Expect = 0.007 Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 18/129 (13%) Query: 154 AAECPAGFVRPP-------LIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVY 206 A CPAG PP L++ S GFR + PN++ L G + Y+ P Sbjct: 10 AIACPAGRPPPPREEEHSQLLLISFQGFRWDXDQDVDT--PNMDHLAGEGVKAKYLMPPL 67 Query: 207 PTKTFPNLYTLATG--LYPESHGIVGNSMYDP--VFDATFHLRGREK--FNHRWWGGQPL 260 T T P +T G L+ H ++ N M++ +++ +F ++ ++R L Sbjct: 68 VTMTSPFHFTAMPGKLLWVRDHXVIHNMMFNTEMLWNCSFKTTQKKTQCXDNRVLS---L 124 Query: 261 WITATKQGV 269 WITA +QG+ Sbjct: 125 WITAQRQGL 133 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 53.5 bits (127), Expect = 8e-07 Identities = 27/81 (33%), Positives = 32/81 (39%), Gaps = 5/81 (6%) Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117 SC GRC E + C CD C+ Y CC DF +C K RC E Sbjct: 29 SCAGRCGE-GYSRDATCNCDYNCQHYMECCPDFKRVCTAEL----SCKGRCFESFERGRE 83 Query: 118 CHCSEDCLARGDCCTNYQVVC 138 C C C CC +Y+ C Sbjct: 84 CDCDAQCKKYDKCCPDYESFC 104 Score = 34.3 bits (77), Expect = 0.51 Identities = 12/35 (34%), Positives = 20/35 (57%) Query: 107 RCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGE 141 RCGE + + C+C +C +CC +++ VC E Sbjct: 33 RCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTAE 67 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 53.5 bits (127), Expect = 8e-07 Identities = 27/81 (33%), Positives = 32/81 (39%), Gaps = 5/81 (6%) Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117 SC GRC E + C CD C+ Y CC DF +C K RC E Sbjct: 29 SCAGRCGE-GYSRDATCNCDYNCQHYMECCPDFKRVCTAEL----SCKGRCFESFERGRE 83 Query: 118 CHCSEDCLARGDCCTNYQVVC 138 C C C CC +Y+ C Sbjct: 84 CDCDAQCKKYDKCCPDYESFC 104 Score = 34.3 bits (77), Expect = 0.51 Identities = 12/35 (34%), Positives = 20/35 (57%) Query: 107 RCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGE 141 RCGE + + C+C +C +CC +++ VC E Sbjct: 33 RCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTAE 67 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 49.3 bits (116), Expect = 2e-05 Identities = 20/37 (54%), Positives = 23/37 (62%), Gaps = 1/37 (2%) Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELC 94 SCKGRCFE E G +C CD CK Y CC D++ C Sbjct: 28 SCKGRCFESFERGR-ECDCDAQCKKYDKCCPDYESFC 63 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 49.3 bits (116), Expect = 2e-05 Identities = 20/37 (54%), Positives = 23/37 (62%), Gaps = 1/37 (2%) Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELC 94 SCKGRCFE E G +C CD CK Y CC D++ C Sbjct: 28 SCKGRCFESFERGR-ECDCDAQCKKYDKCCPDYESFC 63 >gi|88853069 vitronectin precursor [Homo sapiens] Length = 478 Score = 41.6 bits (96), Expect = 0.003 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 3/54 (5%) Query: 43 PPTVLSDSPWTNISG--SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELC 94 P +L+ W ++ SCKGRC E C+CD LC Y SCC D+ C Sbjct: 6 PLLILALLAWVALADQESCKGRCTEGFNVDKK-CQCDELCSYYQSCCTDYTAEC 58 Score = 37.4 bits (85), Expect = 0.060 Identities = 16/38 (42%), Positives = 18/38 (47%) Query: 102 ECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCK 139 E K RC E N + C C E C CCT+Y CK Sbjct: 22 ESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECK 59 >gi|5174623 placental protein 11 precursor [Homo sapiens] Length = 369 Score = 40.8 bits (94), Expect = 0.005 Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 1/37 (2%) Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELC 94 SC+GRC+E + C C+ C+ + +CC DF+ LC Sbjct: 48 SCQGRCYEAFDKHH-QCHCNARCQEFGNCCKDFESLC 83 Score = 35.8 bits (81), Expect = 0.18 Identities = 15/50 (30%), Positives = 25/50 (50%), Gaps = 2/50 (4%) Query: 107 RCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAE 156 RC E ++ + CHC+ C G+CC +++ +C H V + I E Sbjct: 52 RCYEAFDKHHQCHCNARCQEFGNCCKDFESLC--SDHEVSHSSDAITKEE 99 >gi|38045917 phosphatidylinositol glycan anchor biosynthesis, class O isoform 2 [Homo sapiens] Length = 672 Score = 40.4 bits (93), Expect = 0.007 Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 5/51 (9%) Query: 312 DFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGM 362 D GHK+GP PEM L ++D+++ L++ L+ L ++ GDHGM Sbjct: 235 DHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL-----LVVAGDHGM 280 >gi|23397648 phosphatidylinositol glycan anchor biosynthesis, class O isoform 1 [Homo sapiens] Length = 1089 Score = 40.4 bits (93), Expect = 0.007 Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 5/51 (9%) Query: 312 DFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGM 362 D GHK+GP PEM L ++D+++ L++ L+ L ++ GDHGM Sbjct: 235 DHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL-----LVVAGDHGM 280 >gi|4557733 latent transforming growth factor beta binding protein 2 [Homo sapiens] Length = 1821 Score = 39.7 bits (91), Expect = 0.012 Identities = 41/170 (24%), Positives = 61/170 (35%), Gaps = 53/170 (31%) Query: 44 PTVLSDSPWTNISGSC------------KGRCFELQEAGPP----DCRCDNLCKSYT--- 84 P V S TN GS KG C ++ E P D RC N SYT Sbjct: 937 PGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLA 996 Query: 85 ---------SCCHDFDEL----------CLKTARGWECTKDRCGEVRNEENACHCSEDCL 125 C D +E C + C+ ++ EV ++E C ++C Sbjct: 997 CEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECA 1056 Query: 126 ARGDCCTNYQVVCKG--------ESHWVDDD---CEEIKAAE----CPAG 160 +R C T + +G +WV++D CE++ CP+G Sbjct: 1057 SRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSG 1106 >gi|169217819 PREDICTED: similar to hCG1793095 [Homo sapiens] Length = 167 Score = 37.7 bits (86), Expect = 0.046 Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 2/60 (3%) Query: 163 RPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLY 222 R L++ S D FR +Y + PN++ + G + YM P + T T P +TL TG Y Sbjct: 30 RNKLLLVSFDSFRWNYEQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGEY 87 >gi|239756564 PREDICTED: similar to hCG1793095 [Homo sapiens] Length = 98 Score = 37.7 bits (86), Expect = 0.046 Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 2/60 (3%) Query: 163 RPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLY 222 R L++ S D FR +Y + PN++ + G + YM P + T T P +TL TG Y Sbjct: 30 RNKLLLVSFDSFRWNYEQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGEY 87 >gi|187608744 zinc finger protein 9 isoform 5 [Homo sapiens] Length = 171 Score = 37.7 bits (86), Expect = 0.046 Identities = 29/108 (26%), Positives = 38/108 (35%), Gaps = 15/108 (13%) Query: 60 KGRCFELQEAGPPDC--RCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117 +GR F+ + PD RC C DE C RG KD C E + E Sbjct: 32 RGRGFQFVSSSLPDICYRCGESGHLAKDCDLQEDEACYNCGRGGHIAKD-CKEPKREREQ 90 Query: 118 C--------HCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAEC 157 C H + DC D + GE + DC ++K C Sbjct: 91 CCYNCGKPGHLARDC----DHADEQKCYSCGEFGHIQKDCTKVKCYRC 134 >gi|123702038 keratin associated protein 5-9 [Homo sapiens] Length = 169 Score = 37.7 bits (86), Expect = 0.046 Identities = 23/89 (25%), Positives = 32/89 (35%), Gaps = 8/89 (8%) Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117 SC C G C+C + CK Y S C C + RG C + C + + Sbjct: 81 SCCKPCCCSSGCGSSCCQC-SCCKPYCSQCSCCKPCCSSSGRGSSCCQSSCCKPCCSSSG 139 Query: 118 C-------HCSEDCLARGDCCTNYQVVCK 139 C C + C ++ CC CK Sbjct: 140 CGSSCCQSSCCKPCCSQSRCCVPVCYQCK 168 >gi|209969800 RPE-spondin [Homo sapiens] Length = 264 Score = 36.2 bits (82), Expect = 0.13 Identities = 19/68 (27%), Positives = 24/68 (35%), Gaps = 10/68 (14%) Query: 80 CKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCK 139 C CC D C ARGW + C C + C GDCC +Y C Sbjct: 22 CAEAGRCCPGRDPACF--ARGWRLDR--------VYGTCFCDQACRFTGDCCFDYDRACP 71 Query: 140 GESHWVDD 147 +V + Sbjct: 72 ARPCFVGE 79 >gi|146229331 arylsulfatase A isoform a precursor [Homo sapiens] Length = 507 Score = 35.8 bits (81), Expect = 0.18 Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 10/69 (14%) Query: 307 YSEQPDFSGHKY------GPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360 ++ P FSG + GPFG + L E+D VG LM + L L VIF D+ Sbjct: 227 HTHYPQFSGQSFAERSGRGPFG----DSLMELDAAVGTLMTAIGDLGLLEETLVIFTADN 282 Query: 361 GMEDVTCDR 369 G E + R Sbjct: 283 GPETMRMSR 291 >gi|146229329 arylsulfatase A isoform a precursor [Homo sapiens] Length = 507 Score = 35.8 bits (81), Expect = 0.18 Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 10/69 (14%) Query: 307 YSEQPDFSGHKY------GPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360 ++ P FSG + GPFG + L E+D VG LM + L L VIF D+ Sbjct: 227 HTHYPQFSGQSFAERSGRGPFG----DSLMELDAAVGTLMTAIGDLGLLEETLVIFTADN 282 Query: 361 GMEDVTCDR 369 G E + R Sbjct: 283 GPETMRMSR 291 >gi|146229327 arylsulfatase A isoform b [Homo sapiens] Length = 423 Score = 35.8 bits (81), Expect = 0.18 Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 10/69 (14%) Query: 307 YSEQPDFSGHKY------GPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360 ++ P FSG + GPFG + L E+D VG LM + L L VIF D+ Sbjct: 143 HTHYPQFSGQSFAERSGRGPFG----DSLMELDAAVGTLMTAIGDLGLLEETLVIFTADN 198 Query: 361 GMEDVTCDR 369 G E + R Sbjct: 199 GPETMRMSR 207 >gi|146229324 arylsulfatase A isoform a precursor [Homo sapiens] Length = 507 Score = 35.8 bits (81), Expect = 0.18 Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 10/69 (14%) Query: 307 YSEQPDFSGHKY------GPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360 ++ P FSG + GPFG + L E+D VG LM + L L VIF D+ Sbjct: 227 HTHYPQFSGQSFAERSGRGPFG----DSLMELDAAVGTLMTAIGDLGLLEETLVIFTADN 282 Query: 361 GMEDVTCDR 369 G E + R Sbjct: 283 GPETMRMSR 291 >gi|6005990 arylsulfatase A isoform a precursor [Homo sapiens] Length = 507 Score = 35.8 bits (81), Expect = 0.18 Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 10/69 (14%) Query: 307 YSEQPDFSGHKY------GPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360 ++ P FSG + GPFG + L E+D VG LM + L L VIF D+ Sbjct: 227 HTHYPQFSGQSFAERSGRGPFG----DSLMELDAAVGTLMTAIGDLGLLEETLVIFTADN 282 Query: 361 GMEDVTCDR 369 G E + R Sbjct: 283 GPETMRMSR 291 >gi|187608732 zinc finger protein 9 isoform 2 [Homo sapiens] Length = 178 Score = 35.4 bits (80), Expect = 0.23 Identities = 29/111 (26%), Positives = 37/111 (33%), Gaps = 15/111 (13%) Query: 57 GSCKGRCFELQEAGPPDC--RCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNE 114 G R F+ + PD RC C DE C RG KD C E + E Sbjct: 36 GFTSDRGFQFVSSSLPDICYRCGESGHLAKDCDLQEDEACYNCGRGGHIAKD-CKEPKRE 94 Query: 115 ENAC--------HCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAEC 157 C H + DC D + GE + DC ++K C Sbjct: 95 REQCCYNCGKPGHLARDC----DHADEQKCYSCGEFGHIQKDCTKVKCYRC 141 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.138 0.442 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 37,642,298 Number of Sequences: 37866 Number of extensions: 1873518 Number of successful extensions: 3809 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 21 Number of HSP's successfully gapped in prelim test: 47 Number of HSP's that attempted gapping in prelim test: 3691 Number of HSP's gapped (non-prelim): 121 length of query: 863 length of database: 18,247,518 effective HSP length: 111 effective length of query: 752 effective length of database: 14,044,392 effective search space: 10561382784 effective search space used: 10561382784 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.