Search of human proteins with 91754185

Search of human proteins with 91754185

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|91754185 hypothetical protein LOC254268 [Homo sapiens]
         (836 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|91754185 hypothetical protein LOC254268 [Homo sapiens]            1696   0.0  
gi|151301137 AT-hook transcription factor [Homo sapiens]               53   1e-06
gi|14165274 golgi-associated microtubule-binding protein HOOK3 [...    51   5e-06
gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo ...    50   7e-06
gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo ...    50   7e-06
gi|55770834 centromere protein F [Homo sapiens]                        47   1e-04
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    46   1e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             46   2e-04
gi|21735548 centrosomal protein 2 [Homo sapiens]                       45   3e-04
gi|5032281 dystrophin Dp427c isoform [Homo sapiens]                    44   5e-04
gi|5032291 dystrophin Dp260-2 isoform [Homo sapiens]                   44   5e-04
gi|150036268 dystrophin Dp260-1 isoform [Homo sapiens]                 44   5e-04
gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens]                   44   5e-04
gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]                   44   5e-04
gi|5032285 dystrophin Dp427l isoform [Homo sapiens]                    44   5e-04
gi|5032283 dystrophin Dp427m isoform [Homo sapiens]                    44   5e-04
gi|24308179 CTTNBP2 N-terminal like [Homo sapiens]                     44   5e-04
gi|31542661 transmembrane protein 57 [Homo sapiens]                    43   0.001
gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens]                   43   0.001
gi|87299628 biorientation of chromosomes in cell division 1-like...    42   0.002
gi|32528293 ecto-NOX disulfide-thiol exchanger 2 isoform a [Homo...    42   0.002
gi|32528291 ecto-NOX disulfide-thiol exchanger 2 isoform b [Homo...    42   0.002
gi|44890059 involucrin [Homo sapiens]                                  42   0.003
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     42   0.003
gi|153791839 sodium channel associated protein 1 [Homo sapiens]        42   0.003
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         41   0.005
gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens]     41   0.005
gi|68160937 tripartite motif-containing 25 [Homo sapiens]              40   0.007
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]             40   0.007
gi|41872583 Rho-associated, coiled-coil containing protein kinas...    40   0.009

>gi|91754185 hypothetical protein LOC254268 [Homo sapiens]
          Length = 836

 Score = 1696 bits (4393), Expect = 0.0
 Identities = 836/836 (100%), Positives = 836/836 (100%)

Query: 1   MDEADFSEHTTYKQEDLPYDGDLSQIKIGNDYSFTSKKDGLEVLNQIIFIADDPQEKAMH 60
           MDEADFSEHTTYKQEDLPYDGDLSQIKIGNDYSFTSKKDGLEVLNQIIFIADDPQEKAMH
Sbjct: 1   MDEADFSEHTTYKQEDLPYDGDLSQIKIGNDYSFTSKKDGLEVLNQIIFIADDPQEKAMH 60

Query: 61  SETCGNTAVTIPLGKITENAANKKDEKEKQCTAALHIPANEGDASKSSISDILLHHLSKE 120
           SETCGNTAVTIPLGKITENAANKKDEKEKQCTAALHIPANEGDASKSSISDILLHHLSKE
Sbjct: 61  SETCGNTAVTIPLGKITENAANKKDEKEKQCTAALHIPANEGDASKSSISDILLHHLSKE 120

Query: 121 PFLRGQGIDCETLPEISNADSFEEEAIIKSIISCYNKNSWPKEQTPELTDQLNPKRDGEN 180
           PFLRGQGIDCETLPEISNADSFEEEAIIKSIISCYNKNSWPKEQTPELTDQLNPKRDGEN
Sbjct: 121 PFLRGQGIDCETLPEISNADSFEEEAIIKSIISCYNKNSWPKEQTPELTDQLNPKRDGEN 180

Query: 181 SNKPGSATTTEENTSDLEGPVAAGDSSHQENVNVLTKTKGPGDKQKSYQGQSPQKQQTEK 240
           SNKPGSATTTEENTSDLEGPVAAGDSSHQENVNVLTKTKGPGDKQKSYQGQSPQKQQTEK
Sbjct: 181 SNKPGSATTTEENTSDLEGPVAAGDSSHQENVNVLTKTKGPGDKQKSYQGQSPQKQQTEK 240

Query: 241 ANSGNTFKYGQGQVHYQLPDFSKIAPKVKIPKNKIINKPLAIAKQASFSSKSRDKPTLVQ 300
           ANSGNTFKYGQGQVHYQLPDFSKIAPKVKIPKNKIINKPLAIAKQASFSSKSRDKPTLVQ
Sbjct: 241 ANSGNTFKYGQGQVHYQLPDFSKIAPKVKIPKNKIINKPLAIAKQASFSSKSRDKPTLVQ 300

Query: 301 DSLETTPESNCVEKQHQEQKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQ 360
           DSLETTPESNCVEKQHQEQKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQ
Sbjct: 301 DSLETTPESNCVEKQHQEQKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQ 360

Query: 361 KGTSSSSSYIFQKISQGKQMCQKLKEQTDQLKTKVQEFSKRIKQDSPYHLQDKKLVLEKL 420
           KGTSSSSSYIFQKISQGKQMCQKLKEQTDQLKTKVQEFSKRIKQDSPYHLQDKKLVLEKL
Sbjct: 361 KGTSSSSSYIFQKISQGKQMCQKLKEQTDQLKTKVQEFSKRIKQDSPYHLQDKKLVLEKL 420

Query: 421 QGHLELLEQNFLATKDKHLTLQQQVHKHESTIVGDFDPERKVEGEIFKLEMLLEDVKEKM 480
           QGHLELLEQNFLATKDKHLTLQQQVHKHESTIVGDFDPERKVEGEIFKLEMLLEDVKEKM
Sbjct: 421 QGHLELLEQNFLATKDKHLTLQQQVHKHESTIVGDFDPERKVEGEIFKLEMLLEDVKEKM 480

Query: 481 DESKYTSAPSLPVSSPVTLDDLASTFSSLSNEIPKEHPGHPSGPRGSGGSEVTGTPQGGP 540
           DESKYTSAPSLPVSSPVTLDDLASTFSSLSNEIPKEHPGHPSGPRGSGGSEVTGTPQGGP
Sbjct: 481 DESKYTSAPSLPVSSPVTLDDLASTFSSLSNEIPKEHPGHPSGPRGSGGSEVTGTPQGGP 540

Query: 541 QEAPNEELCELAPQTYLNGHYGDAAAQNKPDQVAMRLSSNSGEDPNGTPRRQDCAEMTAP 600
           QEAPNEELCELAPQTYLNGHYGDAAAQNKPDQVAMRLSSNSGEDPNGTPRRQDCAEMTAP
Sbjct: 541 QEAPNEELCELAPQTYLNGHYGDAAAQNKPDQVAMRLSSNSGEDPNGTPRRQDCAEMTAP 600

Query: 601 SPSCAFCRRLLEWKQNVEKKGHGRINCGRFSIVLHEKAPHSDSTPNSDTGHSFCSDSGTE 660
           SPSCAFCRRLLEWKQNVEKKGHGRINCGRFSIVLHEKAPHSDSTPNSDTGHSFCSDSGTE
Sbjct: 601 SPSCAFCRRLLEWKQNVEKKGHGRINCGRFSIVLHEKAPHSDSTPNSDTGHSFCSDSGTE 660

Query: 661 MQSNKCQDCGTKIPTSRRACRKEPTKEFHYRYNTPGQNYSNHSKRGAFVQPHSLDESKNS 720
           MQSNKCQDCGTKIPTSRRACRKEPTKEFHYRYNTPGQNYSNHSKRGAFVQPHSLDESKNS
Sbjct: 661 MQSNKCQDCGTKIPTSRRACRKEPTKEFHYRYNTPGQNYSNHSKRGAFVQPHSLDESKNS 720

Query: 721 SPSFLKPKRICSQRVNSKSFKGEHEPTPGKKKLQAFMTYSSDPATPSPHFYSCRISGSKS 780
           SPSFLKPKRICSQRVNSKSFKGEHEPTPGKKKLQAFMTYSSDPATPSPHFYSCRISGSKS
Sbjct: 721 SPSFLKPKRICSQRVNSKSFKGEHEPTPGKKKLQAFMTYSSDPATPSPHFYSCRISGSKS 780

Query: 781 LCDFDSTEEIKSEILNSALDHALRTATILKETTDQMIKTIAEDLAKAQRWRNRLKY 836
           LCDFDSTEEIKSEILNSALDHALRTATILKETTDQMIKTIAEDLAKAQRWRNRLKY
Sbjct: 781 LCDFDSTEEIKSEILNSALDHALRTATILKETTDQMIKTIAEDLAKAQRWRNRLKY 836


>gi|151301137 AT-hook transcription factor [Homo sapiens]
          Length = 1439

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 44/163 (26%), Positives = 70/163 (42%), Gaps = 38/163 (23%)

Query: 242 NSGNTFKYGQGQVHYQLPDFSKIAPKVKIPKNKIINKPLAIAKQASFSSKSRDKPTLVQD 301
           +S N  KYG+GQ++Y LPDFSK+ P+V+ PK++    P          S+S ++      
Sbjct: 342 SSSNAPKYGRGQLNYPLPDFSKVGPRVRFPKDESYRPP---------KSRSHNR------ 386

Query: 302 SLETTPESNCVEKQHQEQKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQK 361
                               K   P++ +  +    I QE+L     EA+L+K +P +  
Sbjct: 387 --------------------KPQAPARPLIFKSPAEIVQEVLLS-SGEAALAKDTPPAHP 425

Query: 362 GTSSSSSYIFQKISQGKQMCQKLKEQTDQLKTKVQEFSKRIKQ 404
            T       FQ   Q  ++  +L+E   +L TK  E    I Q
Sbjct: 426 ITRVPQE--FQTPEQATELVHQLQEDYHRLLTKYAEAENTIDQ 466



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 34/112 (30%), Positives = 59/112 (52%), Gaps = 5/112 (4%)

Query: 379 QMCQKLKEQTDQLKTKVQEFSKRIKQDSPYHLQDKKLVLEKLQGHLELLEQNFL-ATKDK 437
           +  Q L  Q  Q   KV+ F +R+ Q      QD+    ++L+     LE+ +L A +++
Sbjct: 561 EQTQALASQASQFLAKVESF-ERLIQAGRLMPQDQVKGFQRLKAAHAALEEEYLKACREQ 619

Query: 438 HLTLQQQVHKHESTIVGDFDPERKVEGEIFKLEMLLEDVKEKMDESKYTSAP 489
           H    Q +   + T  G FDP R++E EI++L   LE++KE +D+++    P
Sbjct: 620 HPA--QPLAGSKGT-PGRFDPRRELEAEIYRLGSCLEELKEHIDQTQQEPEP 668


>gi|14165274 golgi-associated microtubule-binding protein HOOK3
           [Homo sapiens]
          Length = 718

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 71/319 (22%), Positives = 138/319 (43%), Gaps = 53/319 (16%)

Query: 190 TEENTSDLEGPVAAGDSSHQENVNVLTKTKGPGDKQKSY-QGQSPQKQQTEKANSGN--- 245
           + +  S LEG V +     ++  ++  + K   +K   Y Q     +++  KAN+     
Sbjct: 309 SSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEELRKANAARSQL 368

Query: 246 -TFKYGQGQVHYQLPDFSKIAPKVKIPKNKIINKPLAIAKQASFSSKSRDKPTLVQDSL- 303
            T+K    ++  +L + SK A K+     ++  K  ++ K+       +D+    +DSL 
Sbjct: 369 ETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKE-------KDRLRTERDSLK 421

Query: 304 ETTPESNCVEKQHQEQKGKIT----------EPSQQIQMEPIVHIHQELLTGIESEASLS 353
           ET  E  CV    Q Q+G++T          E S  +  E +    +E L  ++ E  + 
Sbjct: 422 ETIEELRCV----QAQEGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKLIRLQHENKML 477

Query: 354 KLSPTSQKGTSSSSSYIFQKISQGKQMCQKLKEQTDQL--------KTKVQEFSKRIKQD 405
           KL+   Q+G+ +    + Q +     + +   E  ++L        +++V+E  K + QD
Sbjct: 478 KLN---QEGSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEELQKSL-QD 533

Query: 406 SPYHLQDKKLVLEKLQGHLELLEQNFLATKDKHLTLQQQVHKHESTIVGDFDPERKVEGE 465
                +D  L+ +KL+ HLE L +              ++ K +  I+ D +P  +    
Sbjct: 534 QGSKAEDSVLLKKKLEEHLEKLHE-----------ANNELQK-KRAIIEDLEP--RFNNS 579

Query: 466 IFKLEMLLEDVKEKMDESK 484
             K+E L E +++K +E K
Sbjct: 580 SLKIEELQEALRKKEEEMK 598


>gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo
           sapiens]
          Length = 788

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 70/339 (20%), Positives = 134/339 (39%), Gaps = 36/339 (10%)

Query: 161 PKEQTPELTDQLNP----KRDGENSNKPGSATTTEENTSDLEGPVAAGDSS---HQENVN 213
           P E++PE+T +       +   E S KPG           + GP   GD +    Q ++ 
Sbjct: 340 PAEESPEVTTEAAEASAVEAGSEVSEKPGQEAPVLPKDGAVNGPSVVGDQTPIEPQTSIE 399

Query: 214 VLTKTK-GPGDKQKSYQGQSPQKQQT-------EKANSGNTFKYGQGQVHYQLPDFSKIA 265
            LT+TK G G ++K      P +++T       E A  G   K  QG       D  +IA
Sbjct: 400 RLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVDTKVAQGATEKSPEDKVQIA 459

Query: 266 PKVKIPKNKIINKPLAIAKQASFSSKSRDKPTLVQDSLETTPESNCVEKQHQEQKGKITE 325
              +  + +   K     + +    K  DK   + +  ++  E+  +++  +E+ G +  
Sbjct: 460 ANEETQEREEQMKEGEETEGSEEDDKENDKTEEMPN--DSVLENKSLQENEEEEIGNLEL 517

Query: 326 PSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIFQKISQGKQMCQKLK 385
               + +  I+   QE       EA L       + G  S  S  + +  +  Q C  L+
Sbjct: 518 AWDMLDLAKIIFKRQE-----TKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQ 572

Query: 386 EQTDQLKTKVQEFSKRIKQDSPYHLQDKKLVLEKLQGHLELLEQNFLATKDKHLTLQQQV 445
           EQ         E   R+  ++ Y L        +    +    ++    +++   L +QV
Sbjct: 573 EQ-------YLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQV 625

Query: 446 HKHESTIVGDFDPERKVEGEIFKLEMLLEDVKEKMDESK 484
            + E +         + + EI +L+ LL +++EK++++K
Sbjct: 626 KEAEGS-------SAEYKKEIEELKELLPEIREKIEDAK 657


>gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo
           sapiens]
          Length = 790

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 70/339 (20%), Positives = 134/339 (39%), Gaps = 36/339 (10%)

Query: 161 PKEQTPELTDQLNP----KRDGENSNKPGSATTTEENTSDLEGPVAAGDSS---HQENVN 213
           P E++PE+T +       +   E S KPG           + GP   GD +    Q ++ 
Sbjct: 342 PAEESPEVTTEAAEASAVEAGSEVSEKPGQEAPVLPKDGAVNGPSVVGDQTPIEPQTSIE 401

Query: 214 VLTKTK-GPGDKQKSYQGQSPQKQQT-------EKANSGNTFKYGQGQVHYQLPDFSKIA 265
            LT+TK G G ++K      P +++T       E A  G   K  QG       D  +IA
Sbjct: 402 RLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVDTKVAQGATEKSPEDKVQIA 461

Query: 266 PKVKIPKNKIINKPLAIAKQASFSSKSRDKPTLVQDSLETTPESNCVEKQHQEQKGKITE 325
              +  + +   K     + +    K  DK   + +  ++  E+  +++  +E+ G +  
Sbjct: 462 ANEETQEREEQMKEGEETEGSEEDDKENDKTEEMPN--DSVLENKSLQENEEEEIGNLEL 519

Query: 326 PSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIFQKISQGKQMCQKLK 385
               + +  I+   QE       EA L       + G  S  S  + +  +  Q C  L+
Sbjct: 520 AWDMLDLAKIIFKRQE-----TKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQ 574

Query: 386 EQTDQLKTKVQEFSKRIKQDSPYHLQDKKLVLEKLQGHLELLEQNFLATKDKHLTLQQQV 445
           EQ         E   R+  ++ Y L        +    +    ++    +++   L +QV
Sbjct: 575 EQ-------YLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQV 627

Query: 446 HKHESTIVGDFDPERKVEGEIFKLEMLLEDVKEKMDESK 484
            + E +         + + EI +L+ LL +++EK++++K
Sbjct: 628 KEAEGS-------SAEYKKEIEELKELLPEIREKIEDAK 659


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 67/308 (21%), Positives = 134/308 (43%), Gaps = 27/308 (8%)

Query: 251  QGQVHYQLPDFSKIAPKVKIPKNKIINKPLAIAKQASFSSKSRDKPTLVQDSLETTPESN 310
            Q ++H      +++  ++   KN++  + L +  +   SSK + K   +++S E     +
Sbjct: 2622 QREMHEMAQKTAELQEELSGEKNRLAGE-LQLLLEEIKSSKDQLKELTLENS-ELKKSLD 2679

Query: 311  CVEKQHQEQKGKITE--PSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSS 368
            C+ K   E++GK+ E     Q+++      HQ LL     +  + ++    +K TS    
Sbjct: 2680 CMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEV-EIQTYREKLTSKEEC 2738

Query: 369  YIFQKISQGKQMCQKLKEQTDQLK--TKVQEFSKRIKQDSPYHLQDKKLVLEKLQGHLEL 426
               QK+        K +E  + LK  T++ E  K+ K D+  ++   K   E+ QG ++L
Sbjct: 2739 LSSQKLEIDLLKSSK-EELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKL 2797

Query: 427  LEQNFLATKDKHLTLQQQV-------HKHESTIVGDFDPERKVEGEIFKLEMLLEDVKEK 479
            L ++    +++   LQ+++        K ++  V D   + ++  EI +L+  LE+  ++
Sbjct: 2798 LIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVD-ELTTEIKELKETLEEKTKE 2856

Query: 480  MDE--SKYTSAPSLPVSSPVTLDDLASTFSSLSNEIPKEHPGHPSGPRGSGGSEVTGTPQ 537
             DE   KY S         ++ + L      L  ++   H       + S GS + G   
Sbjct: 2857 ADEYLDKYCSL-------LISHEKLEKAKEMLETQV--AHLCSQQSKQDSRGSPLLGPVV 2907

Query: 538  GGPQEAPN 545
             GP   P+
Sbjct: 2908 PGPSPIPS 2915


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 56/334 (16%), Positives = 143/334 (42%), Gaps = 20/334 (5%)

Query: 162 KEQTPELTDQLNPKRD--GENSNKPGSATTTEENTSDLEGPVAAGDSSHQENVNVLTKTK 219
           +EQ  ++ +Q    R+  G+   + G     E    + EG V   +   +E    + + +
Sbjct: 83  REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 142

Query: 220 GPGDKQKSYQGQSPQKQQTEKANSGNTFKYGQGQVHYQLPDFSKIAPKVKIPKNKIINKP 279
           G   +Q   +GQ  +++   +   G   +  +GQV  Q     +   +V+  + ++  + 
Sbjct: 143 GQVREQ---EGQVREQEGQVREQEGQV-REQEGQVREQEGQVREQEGQVREQEGQMGEQE 198

Query: 280 LAIAKQASFSSKSRDKPTLVQDSL-ETTPESNCVEKQHQEQKGKITEPSQQIQ------- 331
             + +Q     +  ++    ++ + E   +    E+Q  EQ+ ++ +  +Q+Q       
Sbjct: 199 GQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMR 258

Query: 332 -MEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIFQKISQGKQMCQKLKEQTDQ 390
             E  +   +E +   E +    K     ++ T      + ++  Q ++  ++++EQ +Q
Sbjct: 259 KQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ 318

Query: 391 LKTKVQEFSKRIKQDSPYHLQDKKLVLEKLQGHLELLEQNFLATKDKHLTLQQQVHKHES 450
           ++ + ++  K+ +Q     + ++K  + + +  +   E+     +++    ++QV K E 
Sbjct: 319 MREQEEQMGKQEEQ-----MWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEE 373

Query: 451 TIVGDFDPERKVEGEIFKLEMLLEDVKEKMDESK 484
            +    +  RK E ++ K E  + + KE+M E K
Sbjct: 374 QMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQK 407



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 50/298 (16%), Positives = 125/298 (41%), Gaps = 13/298 (4%)

Query: 162 KEQTPELTDQLNPKRD--GENSNKPGSATTTEENTSDLEGPVAAGDSSHQENVNVLTKTK 219
           +EQ  ++ +Q    R+  G+   + G     E    + EG V   +   +E    + + +
Sbjct: 139 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQE 198

Query: 220 GPGDKQKSYQGQSP---QKQQTEKANSGNTFKYGQGQVHYQLPDFSKIAPKVKIPKNKII 276
           G   +Q+   G+     QKQ+ +        +  + Q+  Q     K   +V+  + ++ 
Sbjct: 199 GQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMR 258

Query: 277 NKPLAIAKQASFSSKSRDKPTLVQDSLETTPESNCVEKQHQEQKGKITEPSQQI-QMEPI 335
            +   + +Q     +  ++    ++  E   ++   E+Q +EQ+ ++ E  +Q+ + E  
Sbjct: 259 KQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ 318

Query: 336 VHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIFQKISQGKQMCQKLKEQTDQLKTKV 395
           +   +E +   E +    K     QK          +++ + ++  QK +EQ  + + ++
Sbjct: 319 MREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE---EQMGEQEEQMQKQEEQVRKQEEQM 375

Query: 396 QEFSKRI-KQDSPYHLQDKKLVLEKLQ---GHLELLEQNFLATKDKHLTLQQQVHKHE 449
           ++  +++ KQ+     Q++++  +K Q      ++ EQ     + K    +Q+ H  E
Sbjct: 376 RKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGE 433


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 59/251 (23%), Positives = 105/251 (41%), Gaps = 39/251 (15%)

Query: 260  DFSKIAPKVKIPKNKIINK---------PLAIAKQASFSSKS--RDKPTLVQDSLETTPE 308
            DF  ++ + KI   ++ N+          + + K+A  +  S  +DK + V DSL+ +  
Sbjct: 815  DFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKS 874

Query: 309  SNCVEKQHQEQKGKITEPSQ---------QIQMEPIVHIHQELLTGIESEASLS---KLS 356
                EK++Q+ K  I +  +         Q+QME  +   +EL   +E E   S   KL 
Sbjct: 875  E--FEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLE 932

Query: 357  PTSQKGTSSSSSYIFQKISQGKQMCQ----KLKEQTDQLKTKVQEFSKRIKQDSPYHLQD 412
              S +     +    ++  + +Q  Q    +LK+ ++Q K +++     +K      +  
Sbjct: 933  LNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELK----IAVLQ 988

Query: 413  KKLVLEKLQGHLELLEQNFLATKDKHLTLQQQVHKHEST---IVGDFDPERKVEGEIFKL 469
            K  +  KLQ  L    Q   A K+K   LQ    K + T   +  DF      E E+   
Sbjct: 989  KTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGR---ESELLAT 1045

Query: 470  EMLLEDVKEKM 480
               L+ V+EK+
Sbjct: 1046 RQDLKSVEEKL 1056



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 47/203 (23%), Positives = 92/203 (45%), Gaps = 24/203 (11%)

Query: 285 QASFSSKSRDKPTLVQDSLETTPESNCVEKQHQEQKGKITEPSQQIQMEPIVHIHQELLT 344
           ++S +  ++   TL ++ L+   +   +E++H E+    +   + IQ      +HQ+ L 
Sbjct: 294 KSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEE----SVSKKNIQAT----LHQKDLD 345

Query: 345 GIESEASLSKLSPTSQKGTSSSSSYIFQKISQGKQMCQKLKEQTDQLKTKVQEFSKRIKQ 404
             + ++ LS         + +S   I  ++S+  +  QKLKE+  +++TK Q      KQ
Sbjct: 346 CQQLQSRLS--------ASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQ 397

Query: 405 DSPYHLQDKKLVLEKLQGHLELLEQNFLATK----DKHLTLQQQVHKHESTIVGDFDPER 460
                 + ++  L+ LQ  +  L    L T+    + H  L++Q       ++   D E+
Sbjct: 398 LQQQREEKEQHGLQ-LQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLM---DKEQ 453

Query: 461 KVEGEIFKLEMLLEDVKEKMDES 483
           +V     KL  L E +KEK+  S
Sbjct: 454 QVADLQLKLSRLEEQLKEKVTNS 476



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 102/514 (19%), Positives = 196/514 (38%), Gaps = 91/514 (17%)

Query: 42   EVLNQIIFIADDPQEKAMHSETCGNTAVTIP--LGKITENAANKKDEKEKQCTAALHIPA 99
            E+ N+I     + Q+  M  E       T+   L K++++  N K E EK          
Sbjct: 829  ELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEK---------- 878

Query: 100  NEGDASKSSISDI------LLHHLS--KEPFLRGQGI---DCETLPEISNADSFEEEAII 148
             E    K++I D+      L H L    E  L+ Q       E   E S+    E  ++ 
Sbjct: 879  -ENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQ 937

Query: 149  KSIISCYNKNSWPKEQTPELTDQLNPKRDGENSNKPGSATTTEENTSDLEGPVAAGDSSH 208
            + +I   N     +++  +L   +N  +      K        +    L+G +       
Sbjct: 938  EQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKK--------KQIEALQGELKIAVLQK 989

Query: 209  QENVNVLTKTKGPGDKQKSYQGQSPQKQQTEKANSGNTFK------YG-QGQVHYQLPDF 261
             E  N L +      ++ + + +     Q     S  TFK      YG + ++     D 
Sbjct: 990  TELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDL 1049

Query: 262  SKIAPKVKIPKNKIINKPLAIAKQASFSSKSRD-KPTLVQDSL--ETTPESNC-----VE 313
              +  K+ + +  +I+    I  Q     + +  K TL QDS   E   +  C     ++
Sbjct: 1050 KSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQ 1109

Query: 314  KQHQ-EQKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIF- 371
            K+   ++K  + E S+  ++E I    ++ +T +  E    KL    +      +  +  
Sbjct: 1110 KEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLI 1169

Query: 372  -QKIS-QGKQMCQKLKEQT---------DQLKTKVQEFSKR-IKQDSPYH--LQDKKLVL 417
             QK+  QGK    K   +          DQ+K + +E  K  I++++  H  +++K++ +
Sbjct: 1170 QQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGM 1229

Query: 418  EK-------LQGHLELLEQNFLATKDKHLTLQQQVHKHE--------------STIVGDF 456
            +K       L   +  L +N    K +  + Q++V + E              +T+  + 
Sbjct: 1230 KKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQ 1289

Query: 457  DPER-------KVEGEIFKLEMLLEDVKEKMDES 483
            D  R       K EGEI KL+  + +++ K+D +
Sbjct: 1290 DERRALLERCLKGEGEIEKLQTKVLELQRKLDNT 1323



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 40/166 (24%), Positives = 74/166 (44%), Gaps = 10/166 (6%)

Query: 293 RDKPTLVQDSLETTPESNC-----VEKQHQEQKGKITEPSQQI-QMEPIVHIHQELLTGI 346
           +++ T + + L+   ES+      +  Q QEQK  +     ++  +E  V+     L   
Sbjct: 574 QEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLN-- 631

Query: 347 ESEASLSKLSPTSQKGTSSSSSYIFQKISQGKQMCQKLKEQTDQLKTKVQEFSKRIKQ-- 404
           ES+  +S+L    +  T    S    K +Q   +   L    + L+ K QE +K   Q  
Sbjct: 632 ESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLD 691

Query: 405 DSPYHLQDKKLVLEKLQGHLELLEQNFLATKDKHLTLQQQVHKHES 450
                LQDK+    +L+ HL+  ++ +L+ + K   L+ Q+ K E+
Sbjct: 692 QVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEA 737


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 49/182 (26%), Positives = 84/182 (46%), Gaps = 26/182 (14%)

Query: 287  SFSSKSRDKPTLVQDSLETTPESNCVEKQHQEQKGKITEPSQQIQMEPIVHIHQELLTGI 346
            +  S  R+K  L     E   E   ++ Q +E++ +      Q+Q+E          T  
Sbjct: 876  ALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLE----------TEK 925

Query: 347  ESEASLSKLSPTSQKGTSSSSSYIFQKISQGKQMCQKLKEQ--TDQLKTKVQEFSKRIKQ 404
            E  + L  L  T ++   +S     +++ Q  ++ QKLKEQ  T  L+T++QE  + +K+
Sbjct: 926  ERVSLLETLLQTQKELADASQQ--LERLRQDMKV-QKLKEQETTGILQTQLQEAQRELKE 982

Query: 405  DSPYHLQDKKLVLEKLQGHLELLEQNFLATKDKHLTLQQQVHKHESTIVGDFDPERKVEG 464
             +  H  D    L  LQ      E++    +DK + LQ+QV   +S +V   D +R VE 
Sbjct: 983  AARQHRDD----LAALQ------EESSSLLQDK-MDLQKQVEDLKSQLVAQDDSQRLVEQ 1031

Query: 465  EI 466
            E+
Sbjct: 1032 EV 1033



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 50/236 (21%), Positives = 96/236 (40%), Gaps = 25/236 (10%)

Query: 281 AIAKQASFSSKSRDKPTLVQD--SLETTPESNCVEKQHQEQKGKI-------TEPSQQIQ 331
           A+   A   + + DK  L Q    LE   +S C   +  EQ            E  ++  
Sbjct: 598 AVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREAL 657

Query: 332 MEPIVHIHQELL----TGIESEASLSKLSPTS---QKGTSSSSSYIFQKISQGKQMCQKL 384
            E   H+  +L      G E +A L  +       QK  S S        +Q +Q+ Q+ 
Sbjct: 658 WEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEA 717

Query: 385 KEQTDQLKTKVQEFSKRIKQDSPYHLQ------DKKLVLEKLQG---HLELLEQNFLATK 435
           K Q + L   VQE    +++ +   ++      D++ + E+LQG     ELLE +    +
Sbjct: 718 KRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQ 777

Query: 436 DKHLTLQQQVHKHESTIVGDFDPERKVEGEIFKLEMLLEDVKEKMDESKYTSAPSL 491
            ++  ++    + E  I      +  ++GE+  L++ L+  + + ++ +  +A  L
Sbjct: 778 QQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQL 833


>gi|5032281 dystrophin Dp427c isoform [Homo sapiens]
          Length = 3677

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 10/120 (8%)

Query: 319  QKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIF-----QK 373
            Q  + TE S  +  E +  I ++L   I  +   +++   +QK  S  +S+       +K
Sbjct: 1362 QSAQETEKSLHLIQESLTFIDKQLAAYIADKVDAAQMPQEAQKIQSDLTSHEISLEEMKK 1421

Query: 374  ISQGKQMCQKLKEQTDQLKTKVQEFSKRIK-----QDSPYHLQDKKLVLEKLQGHLELLE 428
             +QGK+  Q++  Q D  + K+Q+ S + +      +    LQ+ K++L++++ HL  LE
Sbjct: 1422 HNQGKEAAQRVLSQIDVAQKKLQDVSMKFRLFQKPANFEQRLQESKMILDEVKMHLPALE 1481


>gi|5032291 dystrophin Dp260-2 isoform [Homo sapiens]
          Length = 2341

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 10/120 (8%)

Query: 319 QKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIF-----QK 373
           Q  + TE S  +  E +  I ++L   I  +   +++   +QK  S  +S+       +K
Sbjct: 26  QSAQETEKSLHLIQESLTFIDKQLAAYIADKVDAAQMPQEAQKIQSDLTSHEISLEEMKK 85

Query: 374 ISQGKQMCQKLKEQTDQLKTKVQEFSKRIK-----QDSPYHLQDKKLVLEKLQGHLELLE 428
            +QGK+  Q++  Q D  + K+Q+ S + +      +    LQ+ K++L++++ HL  LE
Sbjct: 86  HNQGKEAAQRVLSQIDVAQKKLQDVSMKFRLFQKPANFEQRLQESKMILDEVKMHLPALE 145


>gi|150036268 dystrophin Dp260-1 isoform [Homo sapiens]
          Length = 2344

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 10/120 (8%)

Query: 319 QKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIF-----QK 373
           Q  + TE S  +  E +  I ++L   I  +   +++   +QK  S  +S+       +K
Sbjct: 29  QSAQETEKSLHLIQESLTFIDKQLAAYIADKVDAAQMPQEAQKIQSDLTSHEISLEEMKK 88

Query: 374 ISQGKQMCQKLKEQTDQLKTKVQEFSKRIK-----QDSPYHLQDKKLVLEKLQGHLELLE 428
            +QGK+  Q++  Q D  + K+Q+ S + +      +    LQ+ K++L++++ HL  LE
Sbjct: 89  HNQGKEAAQRVLSQIDVAQKKLQDVSMKFRLFQKPANFEQRLQESKMILDEVKMHLPALE 148


>gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens]
          Length = 3562

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 10/120 (8%)

Query: 319  QKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIF-----QK 373
            Q  + TE S  +  E +  I ++L   I  +   +++   +QK  S  +S+       +K
Sbjct: 1247 QSAQETEKSLHLIQESLTFIDKQLAAYIADKVDAAQMPQEAQKIQSDLTSHEISLEEMKK 1306

Query: 374  ISQGKQMCQKLKEQTDQLKTKVQEFSKRIK-----QDSPYHLQDKKLVLEKLQGHLELLE 428
             +QGK+  Q++  Q D  + K+Q+ S + +      +    LQ+ K++L++++ HL  LE
Sbjct: 1307 HNQGKEAAQRVLSQIDVAQKKLQDVSMKFRLFQKPANFEQRLQESKMILDEVKMHLPALE 1366


>gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]
          Length = 3681

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 10/120 (8%)

Query: 319  QKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIF-----QK 373
            Q  + TE S  +  E +  I ++L   I  +   +++   +QK  S  +S+       +K
Sbjct: 1366 QSAQETEKSLHLIQESLTFIDKQLAAYIADKVDAAQMPQEAQKIQSDLTSHEISLEEMKK 1425

Query: 374  ISQGKQMCQKLKEQTDQLKTKVQEFSKRIK-----QDSPYHLQDKKLVLEKLQGHLELLE 428
             +QGK+  Q++  Q D  + K+Q+ S + +      +    LQ+ K++L++++ HL  LE
Sbjct: 1426 HNQGKEAAQRVLSQIDVAQKKLQDVSMKFRLFQKPANFEQRLQESKMILDEVKMHLPALE 1485


>gi|5032285 dystrophin Dp427l isoform [Homo sapiens]
          Length = 3562

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 10/120 (8%)

Query: 319  QKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIF-----QK 373
            Q  + TE S  +  E +  I ++L   I  +   +++   +QK  S  +S+       +K
Sbjct: 1247 QSAQETEKSLHLIQESLTFIDKQLAAYIADKVDAAQMPQEAQKIQSDLTSHEISLEEMKK 1306

Query: 374  ISQGKQMCQKLKEQTDQLKTKVQEFSKRIK-----QDSPYHLQDKKLVLEKLQGHLELLE 428
             +QGK+  Q++  Q D  + K+Q+ S + +      +    LQ+ K++L++++ HL  LE
Sbjct: 1307 HNQGKEAAQRVLSQIDVAQKKLQDVSMKFRLFQKPANFEQRLQESKMILDEVKMHLPALE 1366


>gi|5032283 dystrophin Dp427m isoform [Homo sapiens]
          Length = 3685

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 10/120 (8%)

Query: 319  QKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIF-----QK 373
            Q  + TE S  +  E +  I ++L   I  +   +++   +QK  S  +S+       +K
Sbjct: 1370 QSAQETEKSLHLIQESLTFIDKQLAAYIADKVDAAQMPQEAQKIQSDLTSHEISLEEMKK 1429

Query: 374  ISQGKQMCQKLKEQTDQLKTKVQEFSKRIK-----QDSPYHLQDKKLVLEKLQGHLELLE 428
             +QGK+  Q++  Q D  + K+Q+ S + +      +    LQ+ K++L++++ HL  LE
Sbjct: 1430 HNQGKEAAQRVLSQIDVAQKKLQDVSMKFRLFQKPANFEQRLQESKMILDEVKMHLPALE 1489


>gi|24308179 CTTNBP2 N-terminal like [Homo sapiens]
          Length = 639

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 70/321 (21%), Positives = 132/321 (41%), Gaps = 35/321 (10%)

Query: 240 KANSGNTF---KYGQGQVHYQLP----DFSKIAPKVKIPKNKIINKPLAIAKQASFSSKS 292
           KA   +TF   +YG+  +   L     DF  +  K    K  +   PL+I K      K+
Sbjct: 33  KAQHRDTFIEERYGKYNISDPLMALQRDFETLKEKNDGEKQPVCTNPLSILKVVMKQCKN 92

Query: 293 RDKPTLVQDSLETTPESNCVEKQHQEQKGKITEPSQQIQMEPIVHIHQELLTG-IESEAS 351
             +  L Q +   +     +    +E++    + ++   +  ++   +E LT  +E E S
Sbjct: 93  MQERMLSQLAAAESRHRKVILDLEEERQRHAQDTAEGDDVTYMLEKERERLTQQLEFEKS 152

Query: 352 LSKLSPTSQKGTSSSSSYIFQKISQGKQMCQKLKEQTDQLKTKVQEFSKRIKQDSPYHLQ 411
             K     QK  SS    + ++ S+ KQ+   L  +  +   K  E  ++  + S     
Sbjct: 153 QVKKFEKEQKKLSSQ---LEEERSRHKQLSSMLVLECKKATNKAAEEGQKAGELS----- 204

Query: 412 DKKLVLEKLQGHLELLEQNFLATKDKHLTLQQQVHKHESTIVGDFDPER-KVEGEIFKLE 470
              L LEK +  +  LE+   A + + L  + QV K     + +FD ER ++  ++ + E
Sbjct: 205 ---LKLEKEKSRVSKLEEELAAERKRGLQTEAQVEKQ----LSEFDIEREQLRAKLNREE 257

Query: 471 MLLEDVKEKMDE----------SKYTSAPSLPVSSPVTLDDLASTFSSLSNEIPKEHPGH 520
              + +KE+M+           S   S+P+  +  PVT+    +T   +   +  +    
Sbjct: 258 NRTKTLKEEMESLKKIVKDLEASHQHSSPNEQLKKPVTVSKGTATEPLMLMSVFCQTESF 317

Query: 521 PS-GPRGSGGSEVTGTPQGGP 540
           P+    GS  +++T T   GP
Sbjct: 318 PAERTHGSNIAKMTNTGLPGP 338


>gi|31542661 transmembrane protein 57 [Homo sapiens]
          Length = 664

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 98/475 (20%), Positives = 190/475 (40%), Gaps = 69/475 (14%)

Query: 83  KKDEKEKQCTAALHIPANEGDASKSSISDILLHHLSKEPFLRGQGIDCETLPEISNADSF 142
           +K EKE +  AA  +P  +        S IL+HH    P  +       TLPEI   +  
Sbjct: 209 QKQEKEAE-EAAKGLPDMD--------SSILIHHNGGIPANKKLST---TLPEIEYREKG 256

Query: 143 EEEA--IIKSIISCYNKNSWPK-----EQTPELTDQLNPKR-------DGENSNKPGSAT 188
           +E+     K  +   N N         ++   + + +N KR         EN  K  S T
Sbjct: 257 KEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCT 316

Query: 189 TTEENTSDLEGPVAAGDSSHQENVNVLTKTKGPGDKQKSYQGQSP--QKQQTEKANSGNT 246
            + +N  +  G V +   SH      +  +    +K++    +SP   K   E     N 
Sbjct: 317 ASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQ 376

Query: 247 FKYGQGQVHYQLPDFSKIAPKVKIPKNKIINKPLAIAKQASFSSKSRDKPTLVQDSLETT 306
                  V  +  D  K+  K  +  ++ + + L    ++  SS S  +  +  +  +  
Sbjct: 377 LSKPDALVRLE-QDIKKL--KADLQASRQVEQEL----RSQISSLSSTERGIRSEMGQLR 429

Query: 307 PESNCVE-KQHQEQKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSS 365
            E+  ++ K H   + K  +     Q+E  +   QE  + +E +    K     ++ T +
Sbjct: 430 QENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEAT-A 488

Query: 366 SSSYIFQKISQGKQMCQKLKEQTDQLKTKVQEFS--KRIKQDSPYHLQDKKLVLEKLQGH 423
           + +  F   S+G +  + L+ +  +L+ + ++ +   ++K+D    L+ K   L K + +
Sbjct: 489 ARAVAFAAASRG-ECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKEN 547

Query: 424 ---LELLEQNFLATKDK------HLTLQQQVHKHESTIVGDFDPERKV-EGEIFKLEMLL 473
               E+L     A +DK       L+ + ++     + +GD   + ++ +G+I + +  +
Sbjct: 548 EKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEI 607

Query: 474 EDVKEK-------MDESKYTSA--PSLPVS----------SPVTLDDLASTFSSL 509
           +D+K+K       M    Y++A  P  PVS          SP  LD  AS +  L
Sbjct: 608 KDLKQKIAEVMAVMPSITYSAATSPLSPVSPHYSSKFVETSPSGLDPNASVYQPL 662


>gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens]
          Length = 1079

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 55/219 (25%), Positives = 92/219 (42%), Gaps = 42/219 (19%)

Query: 280 LAIAKQASFSSKSRDKPTLVQDSLETTPESNCVEKQHQEQKGKITEPSQQI--------- 330
           L  + +  FS +  D  T + ++LE        E  ++EQ GKI   +Q++         
Sbjct: 15  LQSSSETLFSIQLLDFKTSLLEALEELRMRREAEIHYEEQIGKIIVETQELKWQKETLQN 74

Query: 331 QMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIFQKISQGKQMCQKLKEQTDQ 390
           Q E +   H+E +   + +  +   +   +KG    ++ I +K  +G      LKE    
Sbjct: 75  QKETLAEQHKEAMAVFKKQLQMKMCALEEEKGKYQLATEIKEKEIEG------LKETLKA 128

Query: 391 LKTKVQEFSKRIKQDSPYHLQDKKLVLE-KLQGHLELLEQNFLATKDKHLTLQQQVHKHE 449
           L            Q S Y LQ K   +E K+Q HL       LA +D H  L + + K+ 
Sbjct: 129 L------------QVSKYSLQKKVSEMEQKVQLHL-------LAKEDYHKQLSE-IEKYY 168

Query: 450 STIVGDFDPERKVEGEIFKLEMLLEDVKEKMDESKYTSA 488
           +TI G F   ++        E L ++V+E +  +K  SA
Sbjct: 169 ATITGQFGLVKE------NHEKLEQNVREAIQSNKRLSA 201


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 56/281 (19%), Positives = 123/281 (43%), Gaps = 37/281 (13%)

Query: 231 QSPQKQQTEKANSGNTFKYGQGQVHYQLPDFSKIAPKVK-----IPKNKIINKPLAIAKQ 285
           +  +KQ+ EK  S  T   G+  V  +      + PK       + + K++ K +A++K+
Sbjct: 516 EEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKK 575

Query: 286 ASFSSK-----SRDKPTLVQDSLETTPESNCVEKQ---------HQEQKGKITEPSQQIQ 331
               S+     S+ K    +DS ET   S   EK+         H   K + ++P++++ 
Sbjct: 576 RKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLS 635

Query: 332 MEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSY--IFQKISQGKQMCQKLKEQTD 389
               V    +  + +E E      +P   +G    +    + +++ + +   ++ ++Q  
Sbjct: 636 ESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKS 695

Query: 390 QLKTKVQEFSKRIKQDSPYHLQDKKLVLEKLQGHLELLEQNFLATKDKHLTLQQQVHKHE 449
            LK +     K +K+D       K L+ ++++   E  E+    ++DK L+++   HK++
Sbjct: 696 TLKNE-----KHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDK-LSVK---HKYK 746

Query: 450 STIVGDFDPERKVEGEIFKLEMLL---EDVKEKMDESKYTS 487
               GD   +   E E+   E  L   E+++++  ++K +S
Sbjct: 747 ----GDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSS 783


>gi|32528293 ecto-NOX disulfide-thiol exchanger 2 isoform a [Homo
           sapiens]
          Length = 581

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 40/160 (25%), Positives = 71/160 (44%), Gaps = 33/160 (20%)

Query: 331 QMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIFQKISQGKQMCQKLKEQTDQ 390
           Q E I +IH + L GI  E  +       ++ T +  +     +SQ     + LKE+ D 
Sbjct: 336 QAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQA----EALKEENDS 391

Query: 391 LKTKV-----------QEFSKRIKQDSPYHLQDKKLVLEKLQGHLELLEQNFLATKDKHL 439
           L+ ++           QE  K  ++D P   Q  KL+ + LQG  + L           L
Sbjct: 392 LRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHL-----------L 440

Query: 440 TLQQQVHKHESTIVGDFDPERKVEGEIFKLEMLLEDVKEK 479
            +Q++  K E+ +        K++ +  ++E +LE++KEK
Sbjct: 441 KVQEEYKKKEAEL-------EKLKDDKLQVEKMLENLKEK 473


>gi|32528291 ecto-NOX disulfide-thiol exchanger 2 isoform b [Homo
           sapiens]
          Length = 610

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 40/160 (25%), Positives = 71/160 (44%), Gaps = 33/160 (20%)

Query: 331 QMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIFQKISQGKQMCQKLKEQTDQ 390
           Q E I +IH + L GI  E  +       ++ T +  +     +SQ     + LKE+ D 
Sbjct: 365 QAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQA----EALKEENDS 420

Query: 391 LKTKV-----------QEFSKRIKQDSPYHLQDKKLVLEKLQGHLELLEQNFLATKDKHL 439
           L+ ++           QE  K  ++D P   Q  KL+ + LQG  + L           L
Sbjct: 421 LRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHL-----------L 469

Query: 440 TLQQQVHKHESTIVGDFDPERKVEGEIFKLEMLLEDVKEK 479
            +Q++  K E+ +        K++ +  ++E +LE++KEK
Sbjct: 470 KVQEEYKKKEAEL-------EKLKDDKLQVEKMLENLKEK 502


>gi|44890059 involucrin [Homo sapiens]
          Length = 585

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 47/184 (25%), Positives = 79/184 (42%), Gaps = 16/184 (8%)

Query: 296 PTLVQDSLETTPESNCVEKQHQEQKGKITEPSQQIQMEPIVHI-------HQELLTGI-E 347
           P L Q+ L+T P      ++  +Q   +  P Q++ +E  V +       H   + G+ E
Sbjct: 13  PALSQELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPE 72

Query: 348 SEASLSKLSPTSQKGTSS--SSSYIFQKISQGKQMCQKLKEQTD-QLKTKVQEFSKRIKQ 404
            E    +  P  Q+           +QK    +Q  ++ K Q D QL  +++E  K + Q
Sbjct: 73  QECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQ 132

Query: 405 DSPYHL--QDKKLVLEKLQGHLELLEQNFLATKDKHLTLQQQVHKHESTIVGDFDPERKV 462
                L  +D++L ++K Q  LEL EQ       KHL  Q+   KH     G  +   + 
Sbjct: 133 QLDQELVKRDEQLGMKKEQ-LLELPEQQ--EGHLKHLEQQEGQLKHPEQQEGQLELPEQQ 189

Query: 463 EGEI 466
           EG++
Sbjct: 190 EGQL 193


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 96/440 (21%), Positives = 169/440 (38%), Gaps = 66/440 (15%)

Query: 76   ITENAANKKDEKEKQCTAALHIPANEGDASKSSISDILLHHLSKEPFLRGQGIDCETLPE 135
            +T+  A  + +K+  CT        E DA K  + D L+  L K+               
Sbjct: 838  LTKQVAEVEAQKKDVCT--------ELDAHKIQVQD-LMQQLEKQ--------------- 873

Query: 136  ISNADSFEEEAIIKSIISCYNKNSWPKEQTPELTDQLNPKRDGENSN-KPGSATTTEENT 194
                 + E E  +KS+   Y        +  E T Q+  +++      + G     E  T
Sbjct: 874  -----NSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILT 928

Query: 195  SDLEGPVAAGDSSHQENVNVLTKTKGPGDKQKSYQGQSPQKQQTEKANSGNTFKYGQGQV 254
              L    A  DS H  N    TK K    K +  + ++ + Q+T K    +     + ++
Sbjct: 929  QKLS---AKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQ----EAKL 981

Query: 255  HYQLPDFS-KIAPKVKIPKNKIINKPLAIAKQASFSSKSRDKPTLVQDSLETTPESNCVE 313
              +L + + +++ K K    K++   +A A  A  S       T  ++ +E+  E   V 
Sbjct: 982  KKELENTALELSQKEKQFNAKMLE--MAQANSAGISDAVSRLETNQKEQIESLTE---VH 1036

Query: 314  KQHQEQKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIFQK 373
            ++       I E     Q E +  IH+  L   E E +  K              +  +K
Sbjct: 1037 RRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELK---------QKILLFGCEK 1087

Query: 374  ISQGKQMCQKLKEQTDQLKTKVQEFSKRIKQDSPYHLQDKKLVLEKLQGHLELLEQNFLA 433
                K++   LKE+  +  T + E  +++KQ S  H+        KL+ HLE LE +   
Sbjct: 1088 EEMNKEITW-LKEEGVKQDTTLNELQEQLKQKSA-HVNSLAQDETKLKAHLEKLEVDLNK 1145

Query: 434  TKDKHLTLQQQVHKHESTIVGDFDPERKVEGEIFKLEMLLEDVKEKMDESKYTSAPSLPV 493
            +  ++  LQ+Q+ + +     D   +RKV     KL         K  + ++ S  S   
Sbjct: 1146 SLKENTFLQEQLVELKMLAEED---KRKVSELTSKL---------KTTDEEFQSLKSSHE 1193

Query: 494  SSPVTLDDLASTFSSLSNEI 513
             S  +L+D +  F  LS E+
Sbjct: 1194 KSNKSLEDKSLEFKKLSEEL 1213



 Score = 37.7 bits (86), Expect = 0.044
 Identities = 59/340 (17%), Positives = 132/340 (38%), Gaps = 49/340 (14%)

Query: 188 TTTEENTSDLEGPVAAGDSSHQENVNVLTKTKGPGDKQKSYQGQSPQKQQTEKANSGNTF 247
           T  EE     E    A     ++ ++   KT+    K K+   +  +  +        + 
Sbjct: 396 TQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISL 455

Query: 248 KYGQGQVHYQLPDFSKIAPKVKIPKNKIINKPLAIAKQASFSSKSRDKPTLVQDSLETTP 307
           +    +V  ++ D  K + + +I K + +++     K+   + K + +    Q+ ++   
Sbjct: 456 QQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVAL 515

Query: 308 ESNCVE----KQHQEQKGKITEPSQQIQMEPIVHIHQELLTGIESEASL---------SK 354
           E +  E     Q +EQ+  +     ++Q + I+   +  L  ++ EA           S 
Sbjct: 516 EKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESS 575

Query: 355 LSPTSQKGTSSSSSY--------------IFQKISQGKQMCQKLKEQTD----------- 389
           L  + Q+  + S                 I   + + K   + LK Q D           
Sbjct: 576 LEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLK 635

Query: 390 -QLKTKVQEFSKRIKQDSPYHLQDKKLVLEKLQGHLELLEQNFLATKDKHLTLQQQVHKH 448
            Q +T++++  ++ +Q+    L+DK+++    Q H+E + +  L   D   T  + +   
Sbjct: 636 QQYQTEMEKLREKCEQEKETLLKDKEII---FQAHIEEMNEKTLEKLDVKQTELESLSSE 692

Query: 449 ESTIVGDFDPERKVEGEIFKL----EMLLEDVKEKMDESK 484
            S ++       K+E E+  L    + + ++++ KMDE K
Sbjct: 693 LSEVL---KARHKLEEELSVLKDQTDKMKQELEAKMDEQK 729



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 62/338 (18%), Positives = 127/338 (37%), Gaps = 20/338 (5%)

Query: 164 QTPELTDQLNPKRDGENSNKPGSATTTEE-------NTSDLEGPVAAGDSSHQENVNVLT 216
           Q    T + NP+ DGE   + G++  T E          +L         SH+E   +LT
Sbjct: 254 QAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLT 313

Query: 217 KTKGPGDKQKSYQGQSPQK----QQTEKANSGNTFKYGQGQVHYQLPDFSKIAPKVKIPK 272
             K    +Q   + Q  +K       EK       +  +  +     D   +  + K   
Sbjct: 314 SEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQM 373

Query: 273 NKIINKPLAIAKQASFSSKSRDKPTLVQDSLETTPESNCVEKQHQEQKGKITEPSQQIQM 332
           ++ +   +   + A   S+ +   T  ++  E   +S     +  E+     + +++ + 
Sbjct: 374 HETLE--MKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARR 431

Query: 333 EPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIFQKISQGKQMCQKLKEQTDQLK 392
           +    + +++ T IE  +   ++S   +            K S  +Q+ +  K    +L 
Sbjct: 432 KLKAEMDEQIKT-IEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELA 490

Query: 393 TKVQEFSKRIKQDSPYHLQDKKLVLEKLQGHL-----ELLEQNFLATKDKHLTLQQQVHK 447
            K QE +K+++       +  K+ LEK Q        E  +Q  LA ++  L  +  + +
Sbjct: 491 RKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTE 550

Query: 448 HESTIVGDFDPERKVEGEIFKLEMLLE-DVKEKMDESK 484
            E+ +             I +LE  LE  ++E  ++SK
Sbjct: 551 SENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSK 588



 Score = 33.9 bits (76), Expect = 0.64
 Identities = 54/234 (23%), Positives = 103/234 (44%), Gaps = 50/234 (21%)

Query: 283  AKQASFSSKSRDKPTLVQDSLETTPESNCVEKQHQEQKGK---ITEPSQQIQ-MEPIVHI 338
            AK A    K+  K   ++  L +  E    EK+ Q +KG    ++E + ++Q  E  VHI
Sbjct: 1635 AKLAELKRKAEQKIAAIKKQLLSQME----EKEEQYKKGTESHLSELNTKLQEREREVHI 1690

Query: 339  HQELLTGIESEASLSKLSPTSQKGTSSSS-------------------SYIFQKISQGKQ 379
             +E L  +ES  S + + P S K  ++ +                   S + + +++ ++
Sbjct: 1691 LEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEK 1750

Query: 380  MCQKL---KEQT--DQLKTKVQEFSKRIKQDSPYHLQDKKLVLEKLQGHL--ELLEQNFL 432
            + Q++   KE+T     + + Q   + IK +   H + K+   + + GHL  EL E+N  
Sbjct: 1751 LLQRVGQEKEETVSSHFEMRCQYQERLIKLE---HAEAKQHEDQSMIGHLQEELEEKN-- 1805

Query: 433  ATKDKHLTLQQQVHKHESTIVGDFDPERKVEGEIFKLEMLLEDVKEKMDESKYT 486
              K   L + Q V K           +  ++ +   LE + +DV++ + E + T
Sbjct: 1806 --KKYSLIVAQHVEKEGG--------KNNIQAK-QNLENVFDDVQKTLQEKELT 1848


>gi|153791839 sodium channel associated protein 1 [Homo sapiens]
          Length = 688

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 57/226 (25%), Positives = 97/226 (42%), Gaps = 11/226 (4%)

Query: 299 VQDS-LETTPESNCVEKQHQEQKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSP 357
           VQD+ + T  E    +KQ   Q  ++TE    +QME      Q      E +A   +L  
Sbjct: 372 VQDATIRTKKEVANTKKQCNIQISRLTEELSALQMECAEKQGQIERVIKEKKAVEEELEK 431

Query: 358 TSQKGTSSSSSYIFQKISQGKQMCQKLKEQTDQLKTKVQEFSKRIKQ---DSPYHLQDKK 414
             ++G  + S Y  +K+ +  Q     +   D L+ ++     RIKQ   DS   +   +
Sbjct: 432 IYREGRGNESDY--RKLEEMHQRFLVSERSKDDLQLRLTRAENRIKQLETDSSEEISRYQ 489

Query: 415 LVLEKLQGHLELLEQNFLATKDKHLTLQQ---QVHKH-ESTIVGDFDPERKVEGEIFKLE 470
            +++KLQ  LE   +N     ++ L LQQ   Q+ K  ES      + ++K + +I  +E
Sbjct: 490 EMIQKLQNVLESERENCGLVSEQRLKLQQENKQLRKETESLRKIALEAQKKAKVKISTME 549

Query: 471 MLLEDVKEKMDESKYTSAPSLPVSSPVTLDDLASTFSSLSNEIPKE 516
                +KE+  E +         +S V L  L +T    +N   +E
Sbjct: 550 HEF-SIKERGFEVQLREMEDSNRNSIVELRHLLATQQKAANRWKEE 594


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 40/178 (22%), Positives = 82/178 (46%), Gaps = 10/178 (5%)

Query: 312 VEKQHQEQKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIF 371
           +E +  E +  +TE   QI M   +    + L  +  + + S L P   +     +  + 
Sbjct: 233 LELELAENRKLLTEKDAQIAM---MQQRIDRLALLNEKQAASPLEPKELEELRDKNESLT 289

Query: 372 QKISQGKQMCQKLKEQTDQLKTKVQEFSKRIKQDSPYHLQDKKLVLEKLQGHL-ELLEQN 430
            ++ +  + CQ LK +  Q+  K+ + S+    D  + L++    L++LQ  L EL E++
Sbjct: 290 MRLHETLKQCQDLKTEKSQMDRKINQLSEE-NGDLSFKLREFASHLQQLQDALNELTEEH 348

Query: 431 FLATKDKHLTLQQQVHKHESTIVGD----FDPERKVEGEIFKLEMLLEDVKEKMDESK 484
             AT++  L  Q Q+ K  S  + D     +    ++G++ +LE  L  +++   + K
Sbjct: 349 SKATQE-WLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEK 405



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 31/113 (27%), Positives = 56/113 (49%), Gaps = 19/113 (16%)

Query: 314  KQHQEQKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIFQK 373
            K+ +E +  + +  +Q+  +   H      +G +SEA+  +  PT  K  +  +     +
Sbjct: 1078 KELEELRQTVKQLKEQLAKKEKEHASG---SGAQSEAA-GRTEPTGPKLEALRA-----E 1128

Query: 374  ISQGKQMCQKLKEQTDQLKTKVQ-EFSKRIKQDSPYHLQDKKLVLEKLQGHLE 425
            +S+ +Q CQK +EQ D L+  ++ E + R ++DS          LE LQG LE
Sbjct: 1129 VSKLEQQCQKQQEQADSLERSLEAERASRAERDS---------ALETLQGQLE 1172


>gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens]
          Length = 778

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 68/293 (23%), Positives = 116/293 (39%), Gaps = 64/293 (21%)

Query: 157 KNSWPKEQTPELTDQLNPKRDGENSNKPGSATTTEE-------NTSDLEGPVAAGDSSHQ 209
           K+S  +E T    +Q NP R  +N NKP   +T  E       + +D++   A    + +
Sbjct: 377 KSSTTEEVTASQGNQNNPPRQQQNQNKPLDTSTKPESIVIMHASNNDVQASRALRSHNLK 436

Query: 210 ENVNVLTKTKGPGDKQKSY------QGQSPQKQQTEKANSGNTFKYGQGQVH-------Y 256
           E  N     K   DK  S        G +  K++  K      F Y   Q+H        
Sbjct: 437 ETSNTFAPPKQAFDKVLSKNSTGCDSGLNVNKERGHKDQEEKRFSY--QQLHTLSDMDLN 494

Query: 257 QLPDFSK---------------IAPKVKIPKNKIINKPLAIAKQASFSSKSRDKPTLVQD 301
            L + SK               I         K + +P    K  +     +   +    
Sbjct: 495 NLNELSKRHVLLSQKGSQFVYHINTHGSTKNKKQLKQPYTETKYRNLEMLWKFHSSSDSQ 554

Query: 302 SLETTPES--NCVEKQHQEQKGKIT--EPSQ----QIQMEPIVHIHQELLTGIESEASLS 353
           ++  +P+S    + +QHQ+   ++T  +PS+     + + PI       L+ +ESE+ LS
Sbjct: 555 TVRASPDSWLTQIMEQHQQALVQLTDVQPSEGALSSVTLPPI-------LSRVESESQLS 607

Query: 354 KLSPTSQK-----GTSSSSSYIFQKISQGKQMCQKLKEQTDQLKTKVQEFSKR 401
             S  SQ+       S+S  Y+FQ + +GK    K K+++    TK++ + KR
Sbjct: 608 --SERSQRNQVKISRSNSEGYLFQ-LEKGK----KHKKRSSSKNTKLKGYQKR 653


>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
          Length = 630

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 53/272 (19%), Positives = 107/272 (39%), Gaps = 13/272 (4%)

Query: 259 PDFSKIAPKVKIPKNKIINKPLAIAKQASFSSKSRDKPTLVQDSLETTPES-NCVEKQHQ 317
           P+ S+    + + ++K  +        A   +  R K T++   +     + + V  + Q
Sbjct: 169 PEHSECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQ 228

Query: 318 EQKGKITEPSQQIQMEPIVHIHQELLTGIE-SEASLSKLSPTSQKGTSSSSSYIFQKISQ 376
           + +       +Q+Q E     + E+   ++ SE + ++     +K  +S    I+Q + +
Sbjct: 229 DVRMTANRKVEQLQQE-----YTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLK 283

Query: 377 GKQMCQKLKEQTDQLKTKVQEFSKRIKQDSPYHLQDKKLVLEKLQGHLELLEQNFLATKD 436
            K   Q LKE+ +Q  TK  EF    K      +  K + + +++ + +L++    +T D
Sbjct: 284 KKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTID 343

Query: 437 KHLTLQQQVHKHESTIVGDFDPERKVEGEIFKLEMLLEDV-KEKMDESKYTSAPSLP--- 492
               L+Q + + +       DP         K    ++ V KE+    K    P+LP   
Sbjct: 344 LKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKL 403

Query: 493 --VSSPVTLDDLASTFSSLSNEIPKEHPGHPS 522
               +P  L DL       + +    HP   S
Sbjct: 404 PTFGAPEQLVDLKQAGLEAAAKATSSHPNSTS 435


>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
          Length = 231

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 43/212 (20%), Positives = 89/212 (41%), Gaps = 10/212 (4%)

Query: 308 ESNCVEKQHQEQKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSS 367
           + N +++  Q +  K     +  Q+E      Q+ L G E E  + K S + +    S  
Sbjct: 15  KENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDE--VEKYSESEKAADESER 72

Query: 368 SYIFQKISQGKQMCQKLKEQTDQLKTKVQEFSKRIKQDSPYHLQDKKLVLEKLQGHLELL 427
                K+ + + M  + K +  +++ K    +K I +DS    ++    L  L+G LE  
Sbjct: 73  G---MKVIENRAMKDEEKMELQEMQLKE---AKHIAEDSDRKYEEVARKLVILEGELERS 126

Query: 428 EQNFLATKDKHLTLQQQVHKHESTIVGDFDPERKVEGEIFKLEMLLEDVKEKMDESKYTS 487
           E+     + +   L++++   +  +      E +   +  K E  ++ ++EK+ E++  +
Sbjct: 127 EERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRA 186

Query: 488 --APSLPVSSPVTLDDLASTFSSLSNEIPKEH 517
             A         T+DDL  T +S   E  + H
Sbjct: 187 EFAERSVAKLEKTIDDLEETLASAKEENVEIH 218


>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
            [Homo sapiens]
          Length = 1388

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 57/245 (23%), Positives = 106/245 (43%), Gaps = 37/245 (15%)

Query: 297  TLVQDSLETTPESNCVEKQHQEQKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLS 356
            TL +   E    S   E+    +K KI +   +++++ ++  H++ LT  E +A+++ L 
Sbjct: 918  TLTKADSEQLARSIAEEQYSDLEKEKIMK---ELEIKEMMARHKQELT--EKDATIASLE 972

Query: 357  PTSQKGTSSSSSYIFQKISQGKQMCQKLKEQTDQLKTKVQEFSKRIKQDSPYHLQDKKLV 416
             T++  TS  ++   +K    +++  KLK+        VQE   R+K +      +    
Sbjct: 973  ETNRTLTSDVANLANEK----EELNNKLKD--------VQEQLSRLKDE------EISAA 1014

Query: 417  LEKLQGHLELLEQNFLATKDKHLTLQQQVHKHESTIVGDFDPERKVEGEIFKLEMLLEDV 476
              K Q   +LL +  L T+  +  L + +++ E    G+    R+ E E  KL M L+  
Sbjct: 1015 AIKAQFEKQLLTERTLKTQAVN-KLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSE 1073

Query: 477  KEKMDES--KY-----------TSAPSLPVSSPVTLDDLASTFSSLSNEIPKEHPGHPSG 523
            +EK+ +   KY                + +   +TLD   S    L +++   H G  S 
Sbjct: 1074 REKLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSS 1133

Query: 524  PRGSG 528
              GSG
Sbjct: 1134 SIGSG 1138


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.126    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,032,982
Number of Sequences: 37866
Number of extensions: 1883952
Number of successful extensions: 6960
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 317
Number of HSP's that attempted gapping in prelim test: 6451
Number of HSP's gapped (non-prelim): 863
length of query: 836
length of database: 18,247,518
effective HSP length: 111
effective length of query: 725
effective length of database: 14,044,392
effective search space: 10182184200
effective search space used: 10182184200
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.