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Search of human proteins with 90819237
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|90819237 myeloid/lymphoid or mixed-lineage leukemia
(trithorax homolog, Drosophila); translocated to, 4 isoform 1 [Homo
sapiens]
(1834 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora... 3685 0.0
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora... 3293 0.0
gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithora... 3179 0.0
gi|148746195 trichohyalin [Homo sapiens] 93 3e-18
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 80 2e-14
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 78 9e-14
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 77 2e-13
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 77 2e-13
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 77 2e-13
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 76 3e-13
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 75 4e-13
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 75 4e-13
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 75 6e-13
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 74 2e-12
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 74 2e-12
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 74 2e-12
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 74 2e-12
gi|148746189 multiple PDZ domain protein [Homo sapiens] 72 5e-12
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 72 6e-12
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 71 8e-12
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 70 1e-11
gi|93204861 protein phosphatase 1, regulatory (inhibitor) subuni... 70 1e-11
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 69 3e-11
gi|112382257 InaD-like [Homo sapiens] 69 3e-11
gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo ... 69 5e-11
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 68 7e-11
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 68 9e-11
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 68 9e-11
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 68 9e-11
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 68 9e-11
>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 1 [Homo
sapiens]
Length = 1834
Score = 3685 bits (9555), Expect = 0.0
Identities = 1834/1834 (100%), Positives = 1834/1834 (100%)
Query: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI
Sbjct: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
Query: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD
Sbjct: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
Query: 121 DREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQAS 180
DREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQAS
Sbjct: 121 DREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQAS 180
Query: 181 DKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSD 240
DKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSD
Sbjct: 181 DKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSD 240
Query: 241 GRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARVM 300
GRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARVM
Sbjct: 241 GRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARVM 300
Query: 301 LPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLEG 360
LPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLEG
Sbjct: 301 LPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLEG 360
Query: 361 KTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYRL 420
KTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYRL
Sbjct: 361 KTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYRL 420
Query: 421 QLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISETT 480
QLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISETT
Sbjct: 421 QLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISETT 480
Query: 481 MLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDIH 540
MLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDIH
Sbjct: 481 MLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDIH 540
Query: 541 SGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELIL 600
SGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELIL
Sbjct: 541 SGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELIL 600
Query: 601 PASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERTH 660
PASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERTH
Sbjct: 601 PASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERTH 660
Query: 661 KVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAH 720
KVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAH
Sbjct: 661 KVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAH 720
Query: 721 LVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNAA 780
LVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNAA
Sbjct: 721 LVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNAA 780
Query: 781 LTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAADC 840
LTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAADC
Sbjct: 781 LTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAADC 840
Query: 841 HLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIEN 900
HLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIEN
Sbjct: 841 HLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIEN 900
Query: 901 VVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLCQ 960
VVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLCQ
Sbjct: 901 VVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLCQ 960
Query: 961 RGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLS 1020
RGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLS
Sbjct: 961 RGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLS 1020
Query: 1021 IVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRT 1080
IVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRT
Sbjct: 1021 IVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRT 1080
Query: 1081 SSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSP 1140
SSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSP
Sbjct: 1081 SSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSP 1140
Query: 1141 ESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVS 1200
ESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVS
Sbjct: 1141 ESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVS 1200
Query: 1201 TGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHTD 1260
TGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHTD
Sbjct: 1201 TGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHTD 1260
Query: 1261 SNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEH 1320
SNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEH
Sbjct: 1261 SNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEH 1320
Query: 1321 LNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDG 1380
LNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDG
Sbjct: 1321 LNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDG 1380
Query: 1381 MSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKL 1440
MSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKL
Sbjct: 1381 MSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKL 1440
Query: 1441 GQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVS 1500
GQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVS
Sbjct: 1441 GQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVS 1500
Query: 1501 KEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLM 1560
KEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLM
Sbjct: 1501 KEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLM 1560
Query: 1561 LEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEER 1620
LEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEER
Sbjct: 1561 LEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEER 1620
Query: 1621 RRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDE 1680
RRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDE
Sbjct: 1621 RRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDE 1680
Query: 1681 AARRLLEPEAPGLCRPPLPRDYEPPSPSPAPGAPPPPPQRNASYLKTQVLSPDSLFTAKF 1740
AARRLLEPEAPGLCRPPLPRDYEPPSPSPAPGAPPPPPQRNASYLKTQVLSPDSLFTAKF
Sbjct: 1681 AARRLLEPEAPGLCRPPLPRDYEPPSPSPAPGAPPPPPQRNASYLKTQVLSPDSLFTAKF 1740
Query: 1741 VAYNEEEEEEDCSLAGPNSYPGSTGAAVGAHDACRDAKEKRSKSQDADSPGSSGAPENLT 1800
VAYNEEEEEEDCSLAGPNSYPGSTGAAVGAHDACRDAKEKRSKSQDADSPGSSGAPENLT
Sbjct: 1741 VAYNEEEEEEDCSLAGPNSYPGSTGAAVGAHDACRDAKEKRSKSQDADSPGSSGAPENLT 1800
Query: 1801 FKERQRLFSQGQDVSNKVKASRKLTELENELNTK 1834
FKERQRLFSQGQDVSNKVKASRKLTELENELNTK
Sbjct: 1801 FKERQRLFSQGQDVSNKVKASRKLTELENELNTK 1834
>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 2 [Homo
sapiens]
Length = 1651
Score = 3293 bits (8538), Expect = 0.0
Identities = 1646/1660 (99%), Positives = 1646/1660 (99%), Gaps = 14/1660 (0%)
Query: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI
Sbjct: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
Query: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD
Sbjct: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
Query: 121 DREGRFVLKNENDAIPPK-AQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA 179
DREGRFVLKNENDAIPPK AQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA
Sbjct: 121 DREGRFVLKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA 180
Query: 180 SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSS 239
SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSS
Sbjct: 181 SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSS 240
Query: 240 DGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARV 299
DGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARV
Sbjct: 241 DGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARV 300
Query: 300 MLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLE 359
MLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLE
Sbjct: 301 MLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLE 360
Query: 360 GKTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYR 419
GKTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYR
Sbjct: 361 GKTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYR 420
Query: 420 LQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISET 479
LQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISET
Sbjct: 421 LQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISET 480
Query: 480 TMLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDI 539
TMLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDI
Sbjct: 481 TMLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDI 540
Query: 540 HSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELI 599
HSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELI
Sbjct: 541 HSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELI 600
Query: 600 LPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERT 659
LPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERT
Sbjct: 601 LPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERT 660
Query: 660 HKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLA 719
HKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLA
Sbjct: 661 HKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLA 720
Query: 720 HLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNA 779
HLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNA
Sbjct: 721 HLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNA 780
Query: 780 ALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAAD 839
ALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAAD
Sbjct: 781 ALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAAD 840
Query: 840 CHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIE 899
CHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIE
Sbjct: 841 CHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIE 900
Query: 900 NVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLC 959
NVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLC
Sbjct: 901 NVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLC 960
Query: 960 QRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGL 1019
QRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGL
Sbjct: 961 QRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGL 1020
Query: 1020 SIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTR 1079
SIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTR
Sbjct: 1021 SIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTR 1080
Query: 1080 TSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGS 1139
TSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGS
Sbjct: 1081 TSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGS 1140
Query: 1140 PESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSV 1199
PESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSV
Sbjct: 1141 PESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSV 1200
Query: 1200 STGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHT 1259
STGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHT
Sbjct: 1201 STGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHT 1260
Query: 1260 DSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQE 1319
DSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQE
Sbjct: 1261 DSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQE 1320
Query: 1320 HLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFD 1379
HLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFD
Sbjct: 1321 HLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFD 1380
Query: 1380 GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK 1439
GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK
Sbjct: 1381 GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK 1440
Query: 1440 LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV 1499
LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV
Sbjct: 1441 LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV 1500
Query: 1500 SKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL 1559
SKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL
Sbjct: 1501 SKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL 1560
Query: 1560 MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEE 1619
MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR DEE
Sbjct: 1561 MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR-------------DEE 1607
Query: 1620 RRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEK 1659
RRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEK
Sbjct: 1608 RRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEK 1647
>gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 3 [Homo
sapiens]
Length = 1612
Score = 3179 bits (8242), Expect = 0.0
Identities = 1588/1603 (99%), Positives = 1588/1603 (99%), Gaps = 15/1603 (0%)
Query: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI
Sbjct: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
Query: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD
Sbjct: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
Query: 121 DREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQAS 180
DREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQAS
Sbjct: 121 DREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQAS 180
Query: 181 DKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSD 240
DKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSD
Sbjct: 181 DKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSD 240
Query: 241 GRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARVM 300
GRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARVM
Sbjct: 241 GRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARVM 300
Query: 301 LPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLEG 360
LPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLEG
Sbjct: 301 LPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLEG 360
Query: 361 KTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYRL 420
KTPKGKERADGSGYGSTLPPEKLPYLVELSP DGSDSRDKPKLYRL
Sbjct: 361 KTPKGKERADGSGYGSTLPPEKLPYLVELSP---------------DGSDSRDKPKLYRL 405
Query: 421 QLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISETT 480
QLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISETT
Sbjct: 406 QLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISETT 465
Query: 481 MLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDIH 540
MLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDIH
Sbjct: 466 MLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDIH 525
Query: 541 SGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELIL 600
SGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELIL
Sbjct: 526 SGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELIL 585
Query: 601 PASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERTH 660
PASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERTH
Sbjct: 586 PASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERTH 645
Query: 661 KVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAH 720
KVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAH
Sbjct: 646 KVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAH 705
Query: 721 LVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNAA 780
LVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNAA
Sbjct: 706 LVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNAA 765
Query: 781 LTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAADC 840
LTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAADC
Sbjct: 766 LTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAADC 825
Query: 841 HLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIEN 900
HLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIEN
Sbjct: 826 HLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIEN 885
Query: 901 VVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLCQ 960
VVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLCQ
Sbjct: 886 VVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLCQ 945
Query: 961 RGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLS 1020
RGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLS
Sbjct: 946 RGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLS 1005
Query: 1021 IVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRT 1080
IVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRT
Sbjct: 1006 IVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRT 1065
Query: 1081 SSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSP 1140
SSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSP
Sbjct: 1066 SSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSP 1125
Query: 1141 ESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVS 1200
ESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVS
Sbjct: 1126 ESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVS 1185
Query: 1201 TGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHTD 1260
TGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHTD
Sbjct: 1186 TGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHTD 1245
Query: 1261 SNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEH 1320
SNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEH
Sbjct: 1246 SNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEH 1305
Query: 1321 LNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDG 1380
LNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDG
Sbjct: 1306 LNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDG 1365
Query: 1381 MSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKL 1440
MSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKL
Sbjct: 1366 MSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKL 1425
Query: 1441 GQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVS 1500
GQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVS
Sbjct: 1426 GQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVS 1485
Query: 1501 KEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLM 1560
KEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLM
Sbjct: 1486 KEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLM 1545
Query: 1561 LEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR 1603
LEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR
Sbjct: 1546 LEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR 1588
Score = 31.2 bits (69), Expect = 9.7
Identities = 28/109 (25%), Positives = 44/109 (40%), Gaps = 6/109 (5%)
Query: 1628 EMRKREAEDRARQEEERRRQEE-ERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLL 1686
E RKRE R ++E+ R +EE ER +R+ E K Q R ++ + +
Sbjct: 1392 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQ-----MRTQSLNPAPFSPLTAQQM 1446
Query: 1687 EPEAPGLCRPPLPRDYEPPSPSPAPGAPPPPPQRNASYLKTQVLSPDSL 1735
+PE P + P P P + + K ++ S DSL
Sbjct: 1447 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSL 1495
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 92.8 bits (229), Expect = 3e-18
Identities = 79/316 (25%), Positives = 150/316 (47%), Gaps = 49/316 (15%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRR------------EQERKLGQMRTQSLNPAPFS 1454
+ R+R + QR +K + +LEEER+R+R +E++L Q + L
Sbjct: 860 QERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREERE 919
Query: 1455 PLTAQQMKPE--KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSP 1512
Q+ + + + LQ+ +E ++RE +++ R + R+ QY K + L
Sbjct: 920 KRRRQEQERQYREEEQLQQEEEQLLRE---EREKRRRQERERQYRKDKKLQQKEEQLLGE 976
Query: 1513 DPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQES 1572
+P KR +E+ +K +E +ELQ + ++ E +R ++ EW+ Q R ++
Sbjct: 977 EPEKRRRQEREKKY----------REEEELQQEEEQLLRE-EREKRRRQEWERQYRKKDE 1025
Query: 1573 KQKDEDD-------------------EEEEDDDVDTMLIMQRLEAERRARTAMPAISVLD 1613
Q++E+ EEEE + L+ + E RR +
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
Query: 1614 LLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAE 1673
L Q+EE+ +++ E+ R++E E + R+EEE +++EE+ + + E++RRQE R E E
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEE 1145
Query: 1674 RRRQHDEAARRLLEPE 1689
+++ ++ R EPE
Sbjct: 1146 VQQEEEQLLRE--EPE 1159
Score = 92.4 bits (228), Expect = 4e-18
Identities = 79/285 (27%), Positives = 144/285 (50%), Gaps = 17/285 (5%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRREQER------KLGQMRTQSLNPAPFSPLTAQQ 1460
ER+ REE Q E+E+ EE +R+R+E+ER KL Q Q L P ++
Sbjct: 927 ERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER 986
Query: 1461 MKP-EKPSTLQRPQETVIRELQPQQQPRTIER--RDLQYITVSKEELSSGDSLSPDPWKR 1517
K + LQ+ +E ++RE + +++ + ER R + +E+L + +R
Sbjct: 987 EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
Query: 1518 DAKEKLEKQQQMHIVDMLSKEI-----QELQSKPDRSAEESDRLRKLMLEWQFQKRLQES 1572
+ + + E++ Q +L +E QEL+ + + E +L+ E ++R QE
Sbjct: 1047 ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106
Query: 1573 KQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKR 1632
+++ ++EE + ++ L+ + E RR ++ Q+EE+ +++ E+ R++
Sbjct: 1107 ERQCREEEELQQEE--EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQ 1164
Query: 1633 EAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQ 1677
E E + R+EEE +QEEE+ R+ +EKRRQE R E E +RQ
Sbjct: 1165 ELERQYREEEEL-QQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208
Score = 88.2 bits (217), Expect = 7e-17
Identities = 83/304 (27%), Positives = 147/304 (48%), Gaps = 23/304 (7%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRREQ-------ERKLGQMRTQSLNPAPFSPLTAQ 1459
ER+ REE + E+E+ L EERE++RR++ E ++ Q Q L P +
Sbjct: 1107 ERQCREEEELQQEEEQL-LREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE 1165
Query: 1460 -QMKPEKPSTLQRPQETVIRELQP---QQQPRTIERRDLQYITVSKEELSSGDSLSPDPW 1515
+ + + LQ+ +E ++RE Q Q++ R + K+ D S W
Sbjct: 1166 LERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKW 1225
Query: 1516 KRDA-KEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESK- 1573
+ + KE + +++ +++ ++L+ R + L+ L+ E Q + R QE +
Sbjct: 1226 QWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRR 1285
Query: 1574 --QKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRK 1631
Q+D EEE + + ++ EA+RR R + +L ++E+RRRQ+ + R+
Sbjct: 1286 WQQRDRHFPEEEQLERE-----EQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340
Query: 1632 REAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEAP 1691
E + R+E+ RRQE +R R+ EE R QE+G LE E+R + E R+ L+ E
Sbjct: 1341 EEQLLQEREEQPLRRQERDRKFRE-EELRHQEQG-RKFLEEEQRLRRQERERKFLKEEQQ 1398
Query: 1692 GLCR 1695
C+
Sbjct: 1399 LRCQ 1402
Score = 85.9 bits (211), Expect = 3e-16
Identities = 81/325 (24%), Positives = 154/325 (47%), Gaps = 33/325 (10%)
Query: 1395 QIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRRE-----QERKLGQMRTQSLN 1449
Q G Q +RR+RE +W E+E+A +++ E +RR+ Q + + Q L+
Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLS 785
Query: 1450 PAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIER---RDLQYITVSKEEL-- 1504
P PL Q+ + + Q+ ++ + E + ++Q R R ++LQ++ +E+L
Sbjct: 786 ARP--PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLE-EEEQLQR 842
Query: 1505 --------SSGDSLSPDPWKRDAKEKLEKQQ-QMHIVDMLSKEIQELQSKP---DRSAEE 1552
D L D +R ++E+ Q+ + + + + L +KP ++ +E
Sbjct: 843 RERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKE 902
Query: 1553 SDRLRKLMLEWQFQKRLQESKQKDEDD--EEEEDDDVDTMLIMQRLEAERRARTAMPAIS 1610
L++ E Q ++R + +Q+ E EEE+ + L+ + E RR
Sbjct: 903 QQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRK 962
Query: 1611 VLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQE-EGYYSR 1669
L Q EE+ ++ E+ R++E E + R+EEE +++EE+ + + E++RRQE E Y +
Sbjct: 963 DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK 1022
Query: 1670 -----LEAERRRQHDEAARRLLEPE 1689
E E+ + + RRL E E
Sbjct: 1023 KDELQQEEEQLLREEREKRRLQERE 1047
Score = 85.5 bits (210), Expect = 4e-16
Identities = 82/301 (27%), Positives = 151/301 (50%), Gaps = 44/301 (14%)
Query: 1408 RRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPS 1467
RRK+EE +R ++E+ E++ER+ +++ER+ Q+R + L +Q + +
Sbjct: 307 RRKQEEERREQQEER---REQQERREQQEERREQQLRREQEERRE-QQLRREQEEERREQ 362
Query: 1468 TLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQ 1527
L+R QE RE Q +++ + + L+ +++L L + R +++L ++Q
Sbjct: 363 QLRREQEEERREQQLRREQQLRREQQLR----REQQLRREQQLRREQQLR-REQQLRREQ 417
Query: 1528 QMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQ---KDEDDEEEED 1584
Q+ L +E +E + ++ E+ R ++L KR QE ++ K E++ E +
Sbjct: 418 QLRREQQLRREQEE--ERHEQKHEQERREQRL-------KREQEERRDWLKREEETERHE 468
Query: 1585 DDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRA-----R 1639
+ + + E ERR R L L ++E R +Q++ E+ +RE E+R R
Sbjct: 469 QERRKQQLKRDQEEERRERW-------LKLEEEERREQQERREQQLRREQEERREQRLKR 521
Query: 1640 QEEERRRQE----EERTKRDAEEKRRQ--EEGYYSRLEAERR-----RQHDEAARRLLEP 1688
QEEE R Q+ E++ +R+ EE+R Q + RLE ERR R+ +E +LL+
Sbjct: 522 QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR 581
Query: 1689 E 1689
E
Sbjct: 582 E 582
Score = 84.3 bits (207), Expect = 1e-15
Identities = 75/321 (23%), Positives = 152/321 (47%), Gaps = 55/321 (17%)
Query: 1407 ERRKREEH-----QRWYEKEKARLEEER----------------ERKRRE--QERKLGQM 1443
+R++R+E Q W E+E+ R EEE+ + +RRE + R+ G+
Sbjct: 165 DRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE 224
Query: 1444 RTQSLNPAPFSPLTAQQMKPE--KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSK 1501
Q + ++ + E K T+ R +E ++E +PQ+Q R ++ + Q + +
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ-RELQEEEEQLRKLER 283
Query: 1502 EELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSK--------EIQELQSKPDRSAEES 1553
+EL +R+ +E+ ++QQ++ L + + +E + + +R ++
Sbjct: 284 QEL-----------RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 1554 DRLRKLMLEWQFQKRLQESKQKDEDD--------EEEEDDDVDTMLIMQRLEAERRARTA 1605
+R + + Q ++R Q+ +++ E++ E+EE+ + Q+L E++ R
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE 392
Query: 1606 MPAISVLDLLQDEERRRQQQL--EEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQE 1663
L ++++ RR+QQL E+ +RE + R QEEER Q+ E+ +R+ KR QE
Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE 452
Query: 1664 EGYYSRLEAERRRQHDEAARR 1684
E E +H++ R+
Sbjct: 453 ERRDWLKREEETERHEQERRK 473
Score = 83.6 bits (205), Expect = 2e-15
Identities = 90/325 (27%), Positives = 154/325 (47%), Gaps = 41/325 (12%)
Query: 1408 RRKREEHQRWYE-KEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1466
RR++EE +R + + + +L E++ +R +Q R+ Q+R + QQ++ E+
Sbjct: 365 RREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 424
Query: 1467 STLQRPQETVIRELQPQQQPRTI-------ERRDLQYITVSKEELSSGDSLSPDPWKRDA 1519
L+R QE E + +Q+ R ERRD ++ +E KRD
Sbjct: 425 --LRREQEEERHEQKHEQERREQRLKREQEERRD--WLKREEETERHEQERRKQQLKRDQ 480
Query: 1520 KE-------KLE----KQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKR 1568
+E KLE ++QQ L +E +E + + + EE +RL++ + Q Q R
Sbjct: 481 EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQ-QLR 539
Query: 1569 LQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEE 1628
++ +++++ + EE+ ++ QRL+ E+ R LL+ EE RRQQ+L+
Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ-------LLKREEERRQQRLKR 592
Query: 1629 MRKREAEDRARQEE-ERRRQEEERTKR----DAEEKRRQ-----EEGYYSRLEAERRRQH 1678
++ E R ++EE ER QEE R +R + EE+RRQ EE R + RR Q
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Query: 1679 DEAARRLLEPEAPGLCRPPLPRDYE 1703
+ +RL E L R++E
Sbjct: 653 ERREQRLKREEEEERLEQRLKREHE 677
Score = 82.4 bits (202), Expect = 4e-15
Identities = 67/270 (24%), Positives = 135/270 (50%), Gaps = 22/270 (8%)
Query: 1408 RRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPS 1467
+R++EE + W ++E+ E+ER++++ +R + R + QQ + E+
Sbjct: 448 KREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ- 506
Query: 1468 TLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELS-SGDSLSPDPWKRDAKEKLEKQ 1526
L+R QE E + Q+ R E LQ S+++L + KR+ +++LE++
Sbjct: 507 -LRREQE----ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQE 561
Query: 1527 QQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDD 1586
++ + +E + + D+ + + R+ L+ + ++RL++ +++E + E+++
Sbjct: 562 RREQRLK------REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER 615
Query: 1587 VDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRR 1646
+ L + E ERR + +++E RRQQQL ++ E R ++EEE R
Sbjct: 616 REQRLKREEPEEERRQQLLKS--------EEQEERRQQQLRREQQERREQRLKREEEEER 667
Query: 1647 QEEERTKRDAEEKRRQEEGYYSRLEAERRR 1676
E+R KR+ EE+RR++E E R R
Sbjct: 668 L-EQRLKREHEEERREQELAEEEQEQARER 696
Score = 81.6 bits (200), Expect = 6e-15
Identities = 82/293 (27%), Positives = 131/293 (44%), Gaps = 50/293 (17%)
Query: 1409 RKREEHQRWYEKEKARLEEE----RERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPE 1464
R++EE QR +E +LEEE R +KR+EQER+L + QS Q+ E
Sbjct: 113 RRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEE 172
Query: 1465 KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLE 1524
Q QE R + +Q ++ +E+L + L R+ K++
Sbjct: 173 LWRQRQEWQEREERRAEEEQLQSCKGHETEEF--PDEEQLRRRELLELRRKGREEKQQQR 230
Query: 1525 KQQQMHIVD------------MLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQES 1572
+++Q + +L KE ++LQ EE R R+L E + ++L+
Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQE------EEPQRQRELQEEEEQLRKLERQ 284
Query: 1573 KQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKR 1632
+ + E EEE+ QRL E++ R Q+EERR QQ E R+
Sbjct: 285 ELRRERQEEEQQQ--------QRLRREQQLRRK----------QEEERREQQ---EERRE 323
Query: 1633 EAEDRARQEEERRRQ--EEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAAR 1683
+ E R +QEE R +Q E+ +R+ + +R QEE R E + RR+ +E R
Sbjct: 324 QQERREQQEERREQQLRREQEERREQQLRREQEE---ERREQQLRREQEEERR 373
Score = 81.3 bits (199), Expect = 8e-15
Identities = 76/286 (26%), Positives = 138/286 (48%), Gaps = 40/286 (13%)
Query: 1407 ERRKREEHQRWYEKEKARLE-EERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEK 1465
+R+ REE Q E E+ +L +ER+RK RE+E++L + + L Q+++ +
Sbjct: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF 1725
Query: 1466 PSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEK 1525
Q QET +L+ Q++ R I + +++L + RD K + E+
Sbjct: 1726 REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQE--------RDRKFREEE 1777
Query: 1526 QQQMHIVDMLSKEIQELQSKP-DRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEED 1584
Q + +E Q+L+S+ DR E ++LR+ E Q + + ++ K + E+++ + +
Sbjct: 1778 QLRQE------REEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLE 1831
Query: 1585 DDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQL--EEMRKREAEDRARQEE 1642
+ QRL ER D + R ++Q +E +RE ++ ++EE
Sbjct: 1832 EQE------QRLRQER----------------DRQYRAEEQFATQEKSRREEQELWQEEE 1869
Query: 1643 ERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEP 1688
++RRQE ER R+ +R+Q+E R E + Q + RLLEP
Sbjct: 1870 QKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEP 1915
Score = 79.3 bits (194), Expect = 3e-14
Identities = 70/295 (23%), Positives = 148/295 (50%), Gaps = 32/295 (10%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
Q+ ++ +RE+ R ++ + EEER ++ EQER+ +++ +
Sbjct: 406 QLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE--------------- 450
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQP----RTIERRDLQYITVSKEELSSGDSLSPDPWKR 1517
+ E+ L+R +ET E + ++Q + ERR+ +++ + +EE +R
Sbjct: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEERRE-RWLKLEEEERREQQERREQQLRR 509
Query: 1518 DAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESK--QK 1575
+ +E+ ++Q++ + + Q L+S+ E+ +R R+ +L+ + +KRL++ + Q+
Sbjct: 510 EQEER--REQRLKRQEEEERLQQRLRSEQQLRREQEER-REQLLKREEEKRLEQERREQR 566
Query: 1576 DEDDEEEEDDDV---DTMLIMQRLEAERRARTAMPAI-SVLDLLQDEERRRQQQLEEMRK 1631
+ ++EE D + + QRL+ E+ R ++ L+ EERR Q+ E +
Sbjct: 567 LKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE 626
Query: 1632 REAED---RARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAAR 1683
E ++ ++EERR+Q+ R +++ E+R + E RLE +R+H+E R
Sbjct: 627 EERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERR 681
Score = 79.0 bits (193), Expect = 4e-14
Identities = 84/301 (27%), Positives = 143/301 (47%), Gaps = 33/301 (10%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1466
+R KRE + E+E A E+E+ R+R + Q + +S A S + ++ K E
Sbjct: 670 QRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQ 729
Query: 1467 STLQRPQETVIR---ELQPQQQPRTI-------ERRDLQYITVSKEELSSG-DSLSPDPW 1515
Q +E R ELQ Q++ R +RRD + ++E+ G LS P
Sbjct: 730 RRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPP 789
Query: 1516 KRDAKEK-LEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQ 1574
R+ +E+ L +++ E +E + + + E L+ L E Q Q+R + +
Sbjct: 790 LREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQL 849
Query: 1575 KDEDDEEEEDDDVDTMLIMQR-------LEAERRART----AMPAISVLDLLQDEERRRQ 1623
++E+D +ED + +R LE ER+ R A PA LQ++ R+ Q
Sbjct: 850 QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPA------LQEQLRKEQ 903
Query: 1624 QQL---EEMRKREAEDR-ARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHD 1679
Q L EE +RE ++ RQE+ER+ +EEE+ +++ E+ R+E R E ER+ + D
Sbjct: 904 QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKD 963
Query: 1680 E 1680
+
Sbjct: 964 K 964
Score = 77.8 bits (190), Expect = 9e-14
Identities = 83/308 (26%), Positives = 147/308 (47%), Gaps = 34/308 (11%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
Q E ++EE Q E+ + R +E ER+ R++E +L Q Q L P ++
Sbjct: 1049 QYREEEELQQEEEQLLGEERETRRRQELERQYRKEE-ELQQEEEQLLREEPEKRRRQERE 1107
Query: 1462 KP-EKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAK 1520
+ + LQ+ +E ++RE + +++ + +ER+ + V +EE L +P KR +
Sbjct: 1108 RQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEE---EQLLREEPEKR-RR 1163
Query: 1521 EKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDE 1580
++LE+Q + ++ +E Q L+ + ++ +E +R + E Q QKR Q + +D+ +
Sbjct: 1164 QELERQYREE-EELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSD 1222
Query: 1581 -------EEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEM---- 1629
E+E+ D + + E E+ L+ Q +R+ QQ L+ +
Sbjct: 1223 LKWQWEPEKENAVRDNKVYCKGRENEQ--------FRQLEDSQLRDRQSQQDLQHLLGEQ 1274
Query: 1630 --RKREAEDRARQEEERRRQEEERTKRD--AEEKRR----QEEGYYSRLEAERRRQHDEA 1681
R RE E R Q+ +R EEE+ +R+ E KRR QEE R E E +R+ E
Sbjct: 1275 QERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQET 1334
Query: 1682 ARRLLEPE 1689
R+ E E
Sbjct: 1335 DRKFREEE 1342
Score = 77.4 bits (189), Expect = 1e-13
Identities = 77/293 (26%), Positives = 142/293 (48%), Gaps = 34/293 (11%)
Query: 1407 ERRKREEH-----QRWYEKEKARLEEERERK---RREQERKLGQMRTQSLNPAPFSPLTA 1458
+R KR+E QR +++ R E+E R+ +RE+E++L Q R +
Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Query: 1459 QQMKPE---KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPW 1515
Q +K E + L+R QE + + +++ +E+ + + + +EE P+
Sbjct: 577 QLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE--------PEEE 628
Query: 1516 KRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRL-RKLMLEWQFQKRLQESKQ 1574
+R K E+Q++ L +E QE + + + EE +RL ++L E + ++R QE
Sbjct: 629 RRQQLLKSEEQEERR-QQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELA- 686
Query: 1575 KDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREA 1634
E+++E+ + + + + + + E A + Q+ +RRRQ+Q E+ R+RE+
Sbjct: 687 --EEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES 744
Query: 1635 EDRARQEEE-RRRQEEERTKRD------AEEKR---RQEEGYYSRLEAERRRQ 1677
E + ++EE R+Q+EE +RD AEEK RQ L +R RQ
Sbjct: 745 ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQ 797
Score = 75.5 bits (184), Expect = 4e-13
Identities = 82/322 (25%), Positives = 147/322 (45%), Gaps = 47/322 (14%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQE--RKLGQMRTQSLNPAPFSPLTAQ 1459
Q+ E+++ + R ++EK L EERE KRR QE RK + Q L PL Q
Sbjct: 1298 QLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE-EEQLLQEREEQPLRRQ 1356
Query: 1460 QMKP-----------------EKPSTLQRPQETVIRELQPQQQPRTIER-------RDLQ 1495
+ E+ L+R QE + L+ +QQ R ER RD +
Sbjct: 1357 ERDRKFREEELRHQEQGRKFLEEEQRLRR-QERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
Query: 1496 Y----ITVSKEELSSGDSLSPDPWKRDAKEK--LEKQQQMHIV--DMLSKEIQELQSKPD 1547
+ +S++E +R +E+ LE++QQ+ +E Q LQ + +
Sbjct: 1416 FREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREE 1475
Query: 1548 RSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMP 1607
+ +R RK + E Q +R + ++ E + ++ + + Q+L ++R R
Sbjct: 1476 QQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR---- 1531
Query: 1608 AISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERR--RQEEERTKRDAEEKRRQEEG 1665
LQ+E++ R+Q+ + R+++ + + R+EE+ R R+E++ ++++ + K R EE
Sbjct: 1532 -----KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQ 1586
Query: 1666 YYSRLEAERRRQHDEAARRLLE 1687
R E ER+ DE R E
Sbjct: 1587 KVRRQEQERKFMEDEQQLRRQE 1608
Score = 74.3 bits (181), Expect = 1e-12
Identities = 83/320 (25%), Positives = 145/320 (45%), Gaps = 49/320 (15%)
Query: 1402 QVAAAERRKRE-----EHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPL 1456
Q+ A ER++RE E + ++ + R E E+E + E+E +L Q R +
Sbjct: 797 QLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL-QRRER---------- 845
Query: 1457 TAQQMKPEKPSTLQRPQETVIRELQPQ----------QQPRTIERRDLQYITVSKEELSS 1506
AQQ++ E+ LQ QE R Q Q ++ R R L +E+L
Sbjct: 846 -AQQLQEEEDG-LQEDQER--RRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRK 901
Query: 1507 GDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQ 1566
L + + +E+ EK+++ +E Q Q + EE ++ R+ E Q++
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYR 961
Query: 1567 --KRLQ-----------ESKQKDEDD----EEEEDDDVDTMLIMQRLEAERRARTAMPAI 1609
K+LQ E +++ E + EEEE + L+ + E RR
Sbjct: 962 KDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYR 1021
Query: 1610 SVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSR 1669
+L Q+EE+ +++ E+ R +E E + R+EEE +++EE+ + E +RRQE R
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR 1081
Query: 1670 LEAERRRQHDEAARRLLEPE 1689
E E +++ ++ R EPE
Sbjct: 1082 KEEELQQEEEQLLRE--EPE 1099
Score = 73.2 bits (178), Expect = 2e-12
Identities = 77/297 (25%), Positives = 130/297 (43%), Gaps = 22/297 (7%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQ-MRTQSLNPAPFSPLTAQQMKPEK 1465
+R KRE+ +R + K E ++R +REQE +L Q ++ + + Q++K E+
Sbjct: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
Query: 1466 PSTLQRPQ---ETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEK 1522
P +R Q E + QQ R + R Q + +EE L + + +++
Sbjct: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
Query: 1523 LEKQQQMHIVDMLSKEIQ----ELQSKPD-RSAEESDRLRKLMLEWQFQKRLQESKQKDE 1577
L +++Q + + I +L+S+ D R ++ R RK + Q+R QE ++K
Sbjct: 685 LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ----EGQRRRQEQEEKRR 740
Query: 1578 DDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQ-----QLEEMRKR 1632
E E + Q+ E E+R + ER RQ+ L E R+R
Sbjct: 741 RRESELQWQEEERAHRQQQEEEQRRDFTWQ----WQAEEKSERGRQRLSARPPLREQRER 796
Query: 1633 EAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
+ RQ+ E+R EE K +RR+ E LE E + Q E A++L E E
Sbjct: 797 QLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
Score = 73.2 bits (178), Expect = 2e-12
Identities = 72/292 (24%), Positives = 142/292 (48%), Gaps = 39/292 (13%)
Query: 1408 RRKREEHQ--RWYEKEKARLEEERERKRREQERKL----GQMRTQSLNPAPFSPLTAQQM 1461
R++REE Q R K RLEE++ R R+EQERK Q+R Q QQ+
Sbjct: 1564 RQEREEQQLSRQERDRKFRLEEQKVR-RQEQERKFMEDEQQLRRQE---------GQQQL 1613
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
+ E+ R E +++E + QQ R + RD +++ +EE + D
Sbjct: 1614 RQERDRKF-REDEQLLQEREEQQLHR--QERDRKFL---EEEPQLRRQEREQQLRHDRDR 1667
Query: 1522 KLEKQQQMHIVDMLSKEIQEL--QSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDD 1579
K +++Q+ + E Q+L Q + + EE +LR+ E +F + Q+ ++++ +
Sbjct: 1668 KFREEEQL----LQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELER 1723
Query: 1580 EEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRAR 1639
+ E++ + ++L + R R +L++E+ R +++ +++R++E + + R
Sbjct: 1724 KFREEEQLRQETEQEQLRRQERYRK---------ILEEEQLRPEREEQQLRRQERDRKFR 1774
Query: 1640 QEEERRRQEEERTKR--DAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
+EE+ R++ EE+ R +++ K R+EE E ++ R + E E
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE 1826
Score = 72.8 bits (177), Expect = 3e-12
Identities = 64/283 (22%), Positives = 131/283 (46%), Gaps = 32/283 (11%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRREQERKL----GQMRTQSLNPAPFSPLTAQQMK 1462
+R+ REE R E+ + LEEE+ +R+E+ERK Q+R Q QQ++
Sbjct: 1359 DRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQERE---------QQLR 1409
Query: 1463 PEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEK 1522
++ + ++ +L Q++ R + Q +E ++ +E+
Sbjct: 1410 QDRDRKFREEEQ----QLSRQERDRKFREEEQQVRRQERE-------------RKFLEEE 1452
Query: 1523 LEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEE 1582
+ +Q+ H +E Q LQ + ++ +R RK + E Q +R + ++ E +
Sbjct: 1453 QQLRQERH--RKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRS 1510
Query: 1583 EDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEE 1642
++ + + Q+L ++R R + L + ++RRQ + + R+ E + R+E+
Sbjct: 1511 QEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQ 1570
Query: 1643 ERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRL 1685
+ RQE +R R E+K R++E +E E++ + E ++L
Sbjct: 1571 QLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL 1613
Score = 72.8 bits (177), Expect = 3e-12
Identities = 84/316 (26%), Positives = 148/316 (46%), Gaps = 48/316 (15%)
Query: 1407 ERRKREEHQRWYEKEKARL--EEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPE 1464
+R+ REE Q+ +E+ R EEE++ +R+E+ERK + Q +Q+ E
Sbjct: 1413 DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472
Query: 1465 KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLE 1524
+ QE + L+ +QQ R ER D ++ ++EL S + ++ LE
Sbjct: 1473 REEQQLHRQERDRKFLEEEQQLRRQER-DRKF---REQELRS---------QEPERKFLE 1519
Query: 1525 KQQQMHIVDMLSKEIQELQS------------KPDRSAEESDRLRKLMLEWQFQK----- 1567
++QQ+H K +QE Q DR E ++LR+ E Q +
Sbjct: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDR 1579
Query: 1568 --RLQESKQKDEDDEE---EEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRR 1622
RL+E K + ++ E E++ + Q+L ER R +L ++++ R
Sbjct: 1580 KFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD-RKFREDEQLLQEREEQQLHR 1638
Query: 1623 QQQ----LEE---MRKREAEDRARQEEERRRQEEERTKRDAEEK--RRQEEGYYSRLEAE 1673
Q++ LEE +R++E E + R + +R+ +EEE+ ++ EE+ RRQE R E E
Sbjct: 1639 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFR-EEE 1697
Query: 1674 RRRQHDEAARRLLEPE 1689
++ + E R+ L+ E
Sbjct: 1698 QQLRRQERERKFLQEE 1713
Score = 72.4 bits (176), Expect = 4e-12
Identities = 60/294 (20%), Positives = 133/294 (45%), Gaps = 24/294 (8%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1466
+R KREE + ++ + EE+ ER++++ R+ + R Q L Q++K E
Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHE 677
Query: 1467 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQ 1526
+R ++ + E Q Q + R R + E + + P K++ + + ++Q
Sbjct: 678 E--ERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ 735
Query: 1527 QQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQK----------- 1575
++ + QE + + R +E ++ R +WQ +++ + +Q+
Sbjct: 736 EEKRRRRESELQWQE-EERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQR 794
Query: 1576 DEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAE 1635
+ EE + + + E E+R R L L++EE ++++RE
Sbjct: 795 ERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEE--------QLQRRERA 846
Query: 1636 DRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
+ ++EE+ ++++ER R ++E+RR ++ + E +RR+H A+ L+ +
Sbjct: 847 QQLQEEEDGLQEDQER--RRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQ 898
Score = 72.0 bits (175), Expect = 5e-12
Identities = 73/301 (24%), Positives = 143/301 (47%), Gaps = 23/301 (7%)
Query: 1410 KREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPL---TAQQMKPEKP 1466
+R+E +R + +E+ +L +ER RK RE+E+ L + Q L+ QQ++ ++
Sbjct: 1440 RRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQER 1499
Query: 1467 STLQRPQETVIRELQPQ----QQPRTIERRDLQYITVSKEE-LSSGDSLSPDPWKRDAKE 1521
R QE +R +P+ ++ + + R+ Q + +E+ L + RD K
Sbjct: 1500 DRKFREQE--LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKF 1557
Query: 1522 KLEKQ-QQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQK---DE 1577
+ E+Q +Q LS++ ++ + + + + +E + Q R QE +Q+ +
Sbjct: 1558 REEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQER 1617
Query: 1578 DDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVL-------DLLQDEERRRQQQLEEMR 1630
D + ED+ + Q+L + R R + L L D +R+ +++ + ++
Sbjct: 1618 DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQ 1677
Query: 1631 KREAEDRARQEEERRRQEEERTKRDAEEKRR--QEEGYYSRLEAERRRQHDEAARRLLEP 1688
+ E + RQE +R+ +EEE+ R E +R+ QEE R E ER+ + +E R+ E
Sbjct: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
Query: 1689 E 1689
E
Sbjct: 1738 E 1738
Score = 72.0 bits (175), Expect = 5e-12
Identities = 76/313 (24%), Positives = 139/313 (44%), Gaps = 45/313 (14%)
Query: 1407 ERRKREEHQRWYEKE-KARLEEERERKRREQERKLGQMRTQSLN----PAPFSPLTAQQM 1461
ER+ E+ Q+ +E + +L +ER+RK RE E+ L + Q L+ F Q
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653
Query: 1462 KPEKPSTLQRPQETVIRE------------LQPQQQPRTIERRDLQYITVSKEE--LSSG 1507
+ E+ L+ ++ RE L+ Q++ R + Q +E L
Sbjct: 1654 RQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEE 1713
Query: 1508 DSLSPDPWKRDAKEKLE-----KQQQMHIVDMLSKEIQELQSKPDRSAEE---SDRLRKL 1559
L +R +E+ + +Q+Q+ + K ++E Q +P+R ++ +R RK
Sbjct: 1714 QQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKF 1773
Query: 1560 MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEE 1619
E Q ++ +E + + ++ + + ++ ++L ER + P +EE
Sbjct: 1774 REEEQLRQEREEQQLRSQESDRKFREE-------EQLRQEREEQQLRPQQRDGKYRWEEE 1826
Query: 1620 RRRQQQLEEMRKREAEDRARQ--------EEERRRQEEERTKRDAEEKRRQEEGYYSRLE 1671
Q QLEE +R ++R RQ +E+ R+EE+ ++ E+KRRQE R E
Sbjct: 1827 ---QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREE 1883
Query: 1672 AERRRQHDEAARR 1684
RR+Q +E R
Sbjct: 1884 HIRRQQKEEQRHR 1896
Score = 70.9 bits (172), Expect = 1e-11
Identities = 73/291 (25%), Positives = 144/291 (49%), Gaps = 17/291 (5%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1466
ER +++ H++ E+++ LEEE++ +R+E++RK + +S P QQ+ +
Sbjct: 1472 EREEQQLHRQ--ERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQ-- 1527
Query: 1467 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEEL--SSGDSLSPDPWKRDAKEKLE 1524
QR ++ + E Q ++Q R +RR + +EE + +RD K +LE
Sbjct: 1528 ---QRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLE 1584
Query: 1525 KQQ--QMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQF-QKRLQESKQKDEDDEE 1581
+Q+ + ++ Q+L+ + + +R RK + Q Q+R ++ + E D +
Sbjct: 1585 EQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRK 1644
Query: 1582 --EEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRAR 1639
EE+ + Q+L +R R +L ++++ RRQ++ + R+ E + R +
Sbjct: 1645 FLEEEPQLRRQEREQQLRHDRD-RKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQ 1703
Query: 1640 QEEERRRQEEERTKR-DAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
+ E + QEE++ +R + E K R+EE E E+ R+ E R++LE E
Sbjct: 1704 ERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQ-ERYRKILEEE 1753
Score = 70.1 bits (170), Expect = 2e-11
Identities = 73/261 (27%), Positives = 127/261 (48%), Gaps = 32/261 (12%)
Query: 1465 KPSTLQ-RPQETVIRELQPQQQPRTIE--RRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
K S LQ R QE R +P+ + E +R Q + EL+ G+ S + +E
Sbjct: 106 KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQS------EKQE 159
Query: 1522 KLEKQQQMHIVDMLSKEIQELQSKPDRSAEESD-------RLRKLMLEWQFQKR-LQESK 1573
+LE++ + + L ++ QE Q + +R AEE + E Q ++R L E +
Sbjct: 160 RLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELR 219
Query: 1574 QKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEE----M 1629
+K ++++++ + + + E E R R + + LQ+EE +RQ++L+E +
Sbjct: 220 RKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEE-EKLQEEEPQRQRELQEEEEQL 278
Query: 1630 RKREAED--RARQEEER-----RRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAA 1682
RK E ++ R RQEEE+ RR+++ R K++ E + +QEE R + ERR Q +E
Sbjct: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE---RREQQERREQQEERR 335
Query: 1683 RRLLEPEAPGLCRPPLPRDYE 1703
+ L E L R+ E
Sbjct: 336 EQQLRREQEERREQQLRREQE 356
Score = 69.7 bits (169), Expect = 2e-11
Identities = 63/290 (21%), Positives = 136/290 (46%), Gaps = 35/290 (12%)
Query: 1407 ERRKREEHQRWYEK-----EKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
ER + +E +RW ++ E+ +LE E +++ + ++RK Q Q L Q+
Sbjct: 1276 ERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRK-SQEEKQLLREEREEKRRRQET 1334
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
+ Q QE + L+ Q++ R +L++ ++ L L +R +E
Sbjct: 1335 DRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRL-----RRQERE 1389
Query: 1522 K--LEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDD 1579
+ L+++QQ+ + +E Q Q + + EE +L + + +F++ Q+ ++++ +
Sbjct: 1390 RKFLKEEQQLRCQE---REQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERER 1446
Query: 1580 EEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRAR 1639
+ E++ Q+L ER + ++EE+ Q++ E+ R+ DR
Sbjct: 1447 KFLEEE--------QQLRQERHRK-----------FREEEQLLQEREEQQLHRQERDRKF 1487
Query: 1640 QEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
EEE++ + +ER ++ E++ R +E LE E++ + R+ L+ E
Sbjct: 1488 LEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEE 1537
Score = 58.2 bits (139), Expect = 7e-08
Identities = 83/347 (23%), Positives = 137/347 (39%), Gaps = 49/347 (14%)
Query: 1407 ERRKREEHQRWYEKEKARLEE------ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQ 1460
ER+ REE + E+E+ EE ERER+ RE+E Q R Q Q
Sbjct: 1167 ERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQ 1226
Query: 1461 MKPEKPSTLQRP-------QETVIRELQPQQQPRTIERRDLQYITVSKEE---------- 1503
+PEK + ++ + R+L+ Q ++DLQ++ ++E
Sbjct: 1227 WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRW 1286
Query: 1504 ------LSSGDSLSPDPWK----RDAKEKLEKQ---------QQMHIVDMLSKE----IQ 1540
+ L + K RD K + EKQ ++ D +E +Q
Sbjct: 1287 QQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQ 1346
Query: 1541 ELQSKPDRSAEESDRLRKLMLEWQFQKR--LQESKQKDEDDEEEEDDDVDTMLIMQRLEA 1598
E + +P R E + R+ L Q Q R L+E ++ + E + + L Q E
Sbjct: 1347 EREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQ 1406
Query: 1599 E-RRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAE 1657
+ R+ R L + E R+ ++ E+ +R+ +R EEE++ ++E K E
Sbjct: 1407 QLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE 1466
Query: 1658 EKRRQEEGYYSRLEAERRRQHDEAARRLLEPEAPGLCRPPLPRDYEP 1704
E+ QE ER R+ E ++L E R R EP
Sbjct: 1467 EQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEP 1513
Score = 37.0 bits (84), Expect = 0.18
Identities = 19/45 (42%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQ 1446
Q A E+ +REE + W E+E+ R +ERERK RE+ + Q Q
Sbjct: 1850 QFATQEKSRREEQELWQEEEQKR-RQERERKLREEHIRRQQKEEQ 1893
Score = 36.6 bits (83), Expect = 0.23
Identities = 25/93 (26%), Positives = 48/93 (51%), Gaps = 3/93 (3%)
Query: 145 EKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQASDKDDRPFQGEDVENSRLAAEVYKD 204
E+QE+E Q +R + K+E+++RE++ R+ ++ +R Q E+ +L E ++
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQEERR--EQQERREQQEERREQQLRRE-QEE 345
Query: 205 MPETSFTRTISNPEVVMKRRRQQKLEKRMQEFR 237
E R + RR+Q+ E+R Q+ R
Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQLR 378
Score = 33.9 bits (76), Expect = 1.5
Identities = 32/164 (19%), Positives = 78/164 (47%), Gaps = 7/164 (4%)
Query: 78 KFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKDDREGRFVLKNENDAIPP 137
KFR D ++L + ++H R ++E+P + + + R R E + +
Sbjct: 1620 KFREDEQLLQEREEQ--QLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQ 1677
Query: 138 KAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQASDKDDRPFQGEDVENSRL 197
+ + +QE++ + ++ L ++E++ K +E++ LR+ + +R F+ E E R
Sbjct: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRR--QELERKFREE--EQLRQ 1733
Query: 198 AAEVYKDMPETSFTRTISNPEVVMKRRRQQ-KLEKRMQEFRSSD 240
E + + + + + ++ +R QQ + ++R ++FR +
Sbjct: 1734 ETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEE 1777
Score = 32.7 bits (73), Expect = 3.3
Identities = 26/128 (20%), Positives = 60/128 (46%), Gaps = 13/128 (10%)
Query: 114 QLNWNKDDREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREK 173
QL +++R + + + E + + + +++++E Q KR E+++R++
Sbjct: 537 QLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR--------EEERRQQ 588
Query: 174 EALRQASDKDDRPFQGEDVE----NSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKL 229
R+ ++ ++ + E+VE R + ++ PE + + E + RRQQ+L
Sbjct: 589 RLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSE-EQEERRQQQL 647
Query: 230 EKRMQEFR 237
+ QE R
Sbjct: 648 RREQQERR 655
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 80.1 bits (196), Expect = 2e-14
Identities = 64/295 (21%), Positives = 147/295 (49%), Gaps = 41/295 (13%)
Query: 1407 ERRKREEHQRWYEKEKARLEE---ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKP 1463
E R RE+ + W ++EK + EE ERE+K RE+E MR Q ++M+
Sbjct: 372 EERMREQEKMWEQEEKMQEEERIREREKKMREEEET---MREQE-----------EKMQK 417
Query: 1464 EKPSTLQRPQETVIRELQPQQQPRTIERRDLQY----ITVSKEELSSGDSLSPDPWKRDA 1519
++ + ++ ++ ++ P+Q+ + E+ +Q I +E++ + + K
Sbjct: 418 QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 477
Query: 1520 KEKLEKQ------QQMHIVDMLSK---EIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQ 1570
+EK+ +Q Q+ + D K + + + + +R E+ +R+R+ WQ +++++
Sbjct: 478 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMR 537
Query: 1571 ESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMR 1630
E K+ E +++ D + + E E++ R ++++++E + Q+Q E+MR
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE------EMMREQEEKMQEQEEKMR 591
Query: 1631 KR-----EAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDE 1680
++ E E++ +++EE+ ++EE+ EE + QE+ + E+ ++ +E
Sbjct: 592 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE 646
Score = 73.9 bits (180), Expect = 1e-12
Identities = 68/353 (19%), Positives = 154/353 (43%), Gaps = 54/353 (15%)
Query: 1407 ERRKREEHQRWYEKEKARLEEE---------RERKRREQERKLGQMRTQSLNPAPFSPLT 1457
E+ + +E + W ++EK R +EE R+ K REQE ++ + + + +
Sbjct: 446 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE--QKMW 503
Query: 1458 AQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR 1517
Q+ + + R +E +RE + Q R + + K+ + + + R
Sbjct: 504 DQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563
Query: 1518 DAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDE 1577
+ ++K+ ++++M + ++ +++Q + ++ E+ +++ W+ ++++QE ++K
Sbjct: 564 EREKKMREEEEM-----MREQEEKMQEQEEKMREQEEKM------WEQEEKMQEQEEKMW 612
Query: 1578 DDEEE--EDDDVDTMLIMQRLEAERRARTAMPAISVLD----LLQDEERRRQQ----QLE 1627
+ EE+ E ++ D M + + E+ + + + + + EE+ R+Q Q +
Sbjct: 613 EQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQ 672
Query: 1628 EMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLE---------------- 1671
E + RE E++ + +EE+ R++EE+ + E+ QEE + + E
Sbjct: 673 EEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIR 732
Query: 1672 ------AERRRQHDEAARRLLEPEAPGLCRPPLPRDYEPPSPSPAPGAPPPPP 1718
ER +H+E P + LC EP G+P P
Sbjct: 733 DQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGGEAGEGSPQDNP 785
Score = 70.5 bits (171), Expect = 1e-11
Identities = 71/308 (23%), Positives = 138/308 (44%), Gaps = 56/308 (18%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1466
E + RE+ ++ + +E+ E+E++ REQE+K MR Q + Q + +
Sbjct: 323 EEKMREQEEKMWRQEERLWEQEKQM--REQEQK---MRDQE------ERMWEQDERLREK 371
Query: 1467 STLQRPQETVIRE---LQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKL 1523
R QE + + +Q +++ R E++ + +E+ + W+++ KE
Sbjct: 372 EERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE-- 429
Query: 1524 EKQQQMHIVDMLSK--EIQELQSKPDRSAEESDRLRKLMLEWQFQKRL------------ 1569
QQ + + K E +++Q + ++ E+ +++R W +K++
Sbjct: 430 --WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ 487
Query: 1570 ---QESKQKDED----DEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRR 1622
QE K +D++ D+EE + D L E E R R + +++E++ +
Sbjct: 488 MWEQEEKMRDQEQKMWDQEERMWEQDERL----REKEERMREQKKMWQQEEKMREEKKTQ 543
Query: 1623 QQQ----------LEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEA 1672
+Q+ EE R RE E + R+EEE R++EE+ + E+ R QEE + E
Sbjct: 544 EQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMW---EQ 600
Query: 1673 ERRRQHDE 1680
E + Q E
Sbjct: 601 EEKMQEQE 608
Score = 68.9 bits (167), Expect = 4e-11
Identities = 71/290 (24%), Positives = 137/290 (47%), Gaps = 48/290 (16%)
Query: 1412 EEHQRWYEKEKARLEEERERKRREQERK---LGQMRTQSLNPAPF---SPLTAQQMKPEK 1465
+E R E EK+ ++ + +R+ ER L Q++T +L + L Q+ K K
Sbjct: 193 QEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRK 252
Query: 1466 PSTLQRPQETVIRELQPQ--QQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKL 1523
QE +RE + + +Q + R++ + KE L R+ +E++
Sbjct: 253 QEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQM 312
Query: 1524 EKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEE 1583
++Q++ + ++ ++++ + ++ + +RL W+ +K+++E +QK D EE
Sbjct: 313 QEQEEK-----MWEQEEKMREQEEKMWRQEERL------WEQEKQMREQEQKMRDQEE-- 359
Query: 1584 DDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQL--EEMRKREAEDRARQE 1641
+ E + R R + EER R+Q+ E+ K + E+R R+
Sbjct: 360 ----------RMWEQDERLR------------EKEERMREQEKMWEQEEKMQEEERIRER 397
Query: 1642 EERRRQEEERTKRDAEEK-RRQEEGYYSRLEAERRRQH-DEAARRLLEPE 1689
E++ R+EEE T R+ EEK ++QEE + + E E ++Q E +L E E
Sbjct: 398 EKKMREEEE-TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 446
Score = 65.1 bits (157), Expect = 6e-10
Identities = 55/281 (19%), Positives = 133/281 (47%), Gaps = 25/281 (8%)
Query: 1413 EHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRP 1472
+ + W ++E+ R E+E+K R+QE K+ + + L Q+ K + R
Sbjct: 233 QEEMWRQEEELR---EQEKKIRKQEEKMWRQEER---------LREQEGKMREQEEKMRR 280
Query: 1473 QETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIV 1532
QE +RE + + + + E R+ + + +E++ + W+++ K + ++++
Sbjct: 281 QEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKM---WEQEEKMREQEEKMWRQE 337
Query: 1533 DMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDE---EEEDDDVDT 1589
+ L ++ ++++ + + ++ +R+ W+ +RL+E +++ + E E+E+ +
Sbjct: 338 ERLWEQEKQMREQEQKMRDQEERM------WEQDERLREKEERMREQEKMWEQEEKMQEE 391
Query: 1590 MLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQ-EEERRRQE 1648
I +R + R M Q+E Q++ E ++R E + + E+E+ +++
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451
Query: 1649 EERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
EE+ E+ R QEE + + R+ + E ++ E E
Sbjct: 452 EEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 492
Score = 62.8 bits (151), Expect = 3e-09
Identities = 83/332 (25%), Positives = 146/332 (43%), Gaps = 71/332 (21%)
Query: 1407 ERRKREEHQRWYEKEKARLEEER----ERKRREQERKLGQMRTQSLNPAPFSPLTAQQMK 1462
ER + +E + ++EK R +E+R E++ REQE++L + + L Q+ +
Sbjct: 262 ERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQK----------KLREQEEQ 311
Query: 1463 PEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDS----LSPDPWKRD 1518
++ QE +RE Q ++ R ER Q + ++E D D R+
Sbjct: 312 MQEQEEKMWEQEEKMRE-QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLRE 370
Query: 1519 AKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL---------------MLEW 1563
+E++ +Q++M + +E + ++ + + EE + +R+ EW
Sbjct: 371 KEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW 430
Query: 1564 QFQKRLQESKQK-------DEDDE-----EEEDDDVDTM----LIMQRLEAERRARTAMP 1607
Q Q+RL E K+K E +E EE+ D + M M R E R M
Sbjct: 431 Q-QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM- 488
Query: 1608 AISVLDLLQDEERRRQQQLEEM-----RKREAEDRARQE-----------EERRRQEEER 1651
+ ++D+E++ Q E M R RE E+R R++ EE++ QE+E+
Sbjct: 489 -WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEK 547
Query: 1652 TKRDAEEKRRQEEGYYSRLEAERRRQHDEAAR 1683
D EEK R+EE R ++ R+ +E R
Sbjct: 548 KTWDQEEKMREEERMRER--EKKMREEEEMMR 577
Score = 57.4 bits (137), Expect = 1e-07
Identities = 61/280 (21%), Positives = 127/280 (45%), Gaps = 29/280 (10%)
Query: 1417 WYEKEKARLEE-ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQET 1475
W++K +EE +ER E + + L ++ + S +Q +
Sbjct: 153 WHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKE 212
Query: 1476 VIRELQ------PQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQM 1529
+ R+L+ PQ Q T++ + +E+ W+++ E+L +Q+
Sbjct: 213 LKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE--ERLREQE-- 268
Query: 1530 HIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDT 1589
+ ++ ++++ + R E+ LR+ E + QK+L+E +++ ++ EE+ + +
Sbjct: 269 ---GKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEK 325
Query: 1590 MLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEM-----RKREAEDRARQ---- 1640
M R + E+ R ++++E++ + Q E M R RE E+R R+
Sbjct: 326 M----REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 381
Query: 1641 -EEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHD 1679
E+E + QEEER R+ E+K R+EE E + ++Q +
Sbjct: 382 WEQEEKMQEEERI-REREKKMREEEETMREQEEKMQKQEE 420
Score = 55.5 bits (132), Expect = 5e-07
Identities = 71/315 (22%), Positives = 142/315 (45%), Gaps = 44/315 (13%)
Query: 1387 LPPPPSANQIGLPSAQVAAAERRKR-EEHQRWYEKEKARLEEERERKRREQERKLGQMRT 1445
LPP P ++ + Q AE +K+ ++++W + R +++K+
Sbjct: 7 LPPHPMMSE---KTRQNKLAEAKKKFTDYRQW------NIAGVGTRATDTKKKKINN--- 54
Query: 1446 QSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELS 1505
NP + + EK ++ Q QE + RE++ Q ++ +T K EL
Sbjct: 55 -GTNPETTTSEGCHSPEDEKKASHQH-QEALRREIEAQDHT-------IRILTCQKTELE 105
Query: 1506 SGDSLSPDPWKRDAKEKLEKQQQM--------HIVDMLSKEIQELQS---KPDRSAEESD 1554
+ S D ++ L + + + H L + + + + K DR EE
Sbjct: 106 TALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELT 165
Query: 1555 RLRKLMLEWQFQKRL--QESKQKDEDDEEE----EDDDVDTMLIMQRLEAE-RRARTAMP 1607
+ R + ++ + +E K+K+ + +E+ E + + L ++ L+ + RA+ +P
Sbjct: 166 KERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLP 225
Query: 1608 AISVLDLLQDEERRRQQQLEEMRK--REAEDRARQEEERRRQEEERTKRDAEEKRRQEEG 1665
+ + LQ+E R++++L E K R+ E++ ++EER R++E + R+ EEK R++E
Sbjct: 226 QVQT-NTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKM-REQEEKMRRQEK 283
Query: 1666 YYSRLEAERRRQHDE 1680
E E R Q E
Sbjct: 284 RLREQEKELREQEKE 298
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 77.8 bits (190), Expect = 9e-14
Identities = 69/290 (23%), Positives = 133/290 (45%), Gaps = 17/290 (5%)
Query: 1409 RKREEH---QRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEK 1465
RKR+ H QR EKE+ R + ++RE+ER + R + + ++
Sbjct: 89 RKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETE-------REGERGRDR 141
Query: 1466 PSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEK 1525
+ QR +E R+ + +++ +T R Q ++E + + +EK K
Sbjct: 142 QTDGQRERERQ-RDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK 200
Query: 1526 QQQMHIVDMLSKEIQ-ELQSKPDRSAE---ESDRLRKLMLEWQFQKRLQESKQKDEDDEE 1581
+ H +E + E +++ +R + E DR RK E + Q + + +++ + ++
Sbjct: 201 TEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDK 260
Query: 1582 EEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQE 1641
E + + D R + ER +T + ++ ER+R++Q E R+RE + +E
Sbjct: 261 ERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERE 320
Query: 1642 EERRRQEEER--TKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
ER R+ E + T+RD E++R ++ + ++ ER RQ RR E E
Sbjct: 321 RERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERE 370
Score = 68.2 bits (165), Expect = 7e-11
Identities = 67/300 (22%), Positives = 136/300 (45%), Gaps = 31/300 (10%)
Query: 1404 AAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKP 1463
A ER ++ + +R + E+ R ++ERER++ QER+ + + + N +
Sbjct: 155 AEKERERQTDRERQRQTERNR-QKEREREKNRQERRERERQREKENKT-------EDRHS 206
Query: 1464 EKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV-SKEELSSGDSLSPDPWKRDAKEK 1522
E+ +R +ET E + +++ +T RD Q T +E+ + + S +RD + +
Sbjct: 207 ERGRERERERET---ETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263
Query: 1523 LEKQQQMHIVDMLSKEIQELQSKPDRSAE---ESDRLRKLMLEWQFQKRLQESKQKDEDD 1579
E+ + + ++ K R E E++R R+ E + ++ ++++ +
Sbjct: 264 RERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERER 323
Query: 1580 EEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAE---- 1635
E E + +T ++ E ER+ + + E RRQ + E R+RE +
Sbjct: 324 ERERERQRETERDREK-ERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSA 382
Query: 1636 ----------DRARQEEERRRQEEERT-KRDAEEKRRQEEGYYSRLEAERRRQHDEAARR 1684
DR RQ+E R+ E++R +R+ E++R +E+ S ER R+ ++ R
Sbjct: 383 REREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGR 442
Score = 62.0 bits (149), Expect = 5e-09
Identities = 70/290 (24%), Positives = 125/290 (43%), Gaps = 30/290 (10%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1466
ER ++ E +R +KE+ R E ERE +R + GQ + A + ++
Sbjct: 112 ERDRQREKERNRQKERER-ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQ 170
Query: 1467 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQ 1526
+ R +E RE + +Q R R+ Q +K E + +R+ + + E++
Sbjct: 171 TERNRQKE---REREKNRQER--RERERQREKENKTEDRHSERGRERERERETETETERK 225
Query: 1527 QQMHIVDMLSKEIQELQSKPDRSAE-ESDRLRKLMLEWQFQKRLQESKQKDED-DEEEED 1584
+Q + ++ Q K +R E +++R R E + K + + +D D D +++
Sbjct: 226 RQ-------TDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKE 278
Query: 1585 DDVDTMLIMQRL-----EAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRAR 1639
+ T QR E ER+ + + ER R+++ E R+RE E
Sbjct: 279 RERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDRE 338
Query: 1640 QEEERRRQ-----EEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARR 1684
+E ER+R+ + ER ++ E RRQ E E ER R+ D + R
Sbjct: 339 KERERKRKRQTEMDRERNRQTGREGRRQAE-----RERERERERDRQSAR 383
Score = 45.1 bits (105), Expect = 6e-04
Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 7/74 (9%)
Query: 1617 DEERRRQQQLEEMR-KREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERR 1675
D ER RQ++ E R KR+ E ++ ERRR+++ KRD +R+++ E ER
Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDR------EKERE 106
Query: 1676 RQHDEAARRLLEPE 1689
RQ D R E E
Sbjct: 107 RQTDRERDRQREKE 120
Score = 43.5 bits (101), Expect = 0.002
Identities = 37/126 (29%), Positives = 59/126 (46%), Gaps = 13/126 (10%)
Query: 1575 KDED-DEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKRE 1633
KD D D+ E + + ++ + ER D + +R R++Q + ++RE
Sbjct: 47 KDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERE 106
Query: 1634 AE-----DRARQEEERRRQEEER-TKRDAEEKR-RQEEGYYSR-----LEAERRRQHDEA 1681
+ DR R++E R++E ER T+R+ E R RQ +G R E ER RQ D
Sbjct: 107 RQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRE 166
Query: 1682 ARRLLE 1687
+R E
Sbjct: 167 RQRQTE 172
Score = 40.0 bits (92), Expect = 0.021
Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 13/81 (16%)
Query: 1617 DEERRRQQQLEEMRKR-----------EAEDRARQEEERRRQEEERTKRDAEEK--RRQE 1663
D RRR E R+R + +R RQ+E RR+E+ +T+R+ + K RR+E
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
Query: 1664 EGYYSRLEAERRRQHDEAARR 1684
+ + + + R RQ D R
Sbjct: 85 KDRHRKRDRHRERQRDREKER 105
Score = 37.4 bits (85), Expect = 0.14
Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 6/72 (8%)
Query: 1618 EERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQ 1677
E RR ++Q E R+ E R ++ R+R +RD E++R ++ + ER RQ
Sbjct: 63 ERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQ------TDRERDRQ 116
Query: 1678 HDEAARRLLEPE 1689
++ R E E
Sbjct: 117 REKERNRQKERE 128
Score = 33.1 bits (74), Expect = 2.6
Identities = 27/135 (20%), Positives = 56/135 (41%), Gaps = 12/135 (8%)
Query: 118 NKDDREGRFVLKNENDAIPPKAQSNGPEKQ-EKEGVIQNFKRTLSKKEKKEKKKREKEAL 176
N+ +R R + + + + G E++ E+E + ++ + +E+ ++K E+E
Sbjct: 184 NRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERERE 243
Query: 177 RQAS-----------DKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRR 225
+QA DK+ + D + R E + RT + E KR R
Sbjct: 244 KQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRER 303
Query: 226 QQKLEKRMQEFRSSD 240
Q++ E+ + R +
Sbjct: 304 QRERERERERNRKRE 318
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 77.0 bits (188), Expect = 2e-13
Identities = 75/294 (25%), Positives = 143/294 (48%), Gaps = 22/294 (7%)
Query: 1398 LPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLT 1457
L + A ER ++E +R EKE+ E E+ +K+ +ER L Q++ L F +
Sbjct: 601 LQKVRKAEEERLRQEAKER--EKERILQEHEQIKKKTVRER-LEQIKKTELGAKAFKDID 657
Query: 1458 AQQMKPEKPSTLQRPQ-ETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK 1516
+ ++ P + Q E + +E + Q+ + + + Y +K L P
Sbjct: 658 IEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKR-------LEEIPLI 710
Query: 1517 RDAKEKLEKQQQMHIVDMLSKE-IQELQSKPDRSAEESDRLRKLMLEWQ-FQKRLQESKQ 1574
+ A E+ ++ + M + + +E I +Q + +++ E +R+ +++ + F RL+ ++Q
Sbjct: 711 KSAYEE-QRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQ 769
Query: 1575 KDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRR--QQQLEEMRKR 1632
+++ ++ ++ RLE +R R I+ ++EE+RR +Q L+E +R
Sbjct: 770 SVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREER 829
Query: 1633 EAEDRARQEEE-RRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRL 1685
E +RA++EEE R QE + + E K+RQ E LE E R + E RRL
Sbjct: 830 ERAERAKREEELREYQERVKKLEEVERKKRQRE-----LEIEERERRREEERRL 878
Score = 73.9 bits (180), Expect = 1e-12
Identities = 73/314 (23%), Positives = 144/314 (45%), Gaps = 39/314 (12%)
Query: 1403 VAAAERRKREEHQRWYEKEKARLEEERER------KRREQERKLGQMRTQSLNPAPFSPL 1456
V A + R+EHQR + + +EE +ER +R ++E + + Q + A L
Sbjct: 554 VTAYLKNSRKEHQRILARRQT-IEERKERLESLNIQREKEELEQREAELQKVRKAEEERL 612
Query: 1457 TAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK 1516
+ + EK LQ ++ I++ +++ I++ +L ++ + L PD
Sbjct: 613 RQEAKEREKERILQEHEQ--IKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIM 670
Query: 1517 RDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKD 1576
E+LEK++ KE+QE ++ + +R ++L + +E + KD
Sbjct: 671 AKQVEQLEKEK---------KELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKD 721
Query: 1577 EDD-EEEEDDDVDTMLIMQRLEAERRARTAMPA----ISVLDLLQDEERRRQQQLEEMRK 1631
D E++E++ + TM + + E + R + + V+ L + +++L++ +
Sbjct: 722 MDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEE 781
Query: 1632 REAEDRARQEEERRRQEEE-------RTKRDAEEKRRQEEGYYSRLEAERR--------- 1675
R AE+R + EER+RQ +E R K + E++R +E+ R E ER
Sbjct: 782 RLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEEL 841
Query: 1676 RQHDEAARRLLEPE 1689
R++ E ++L E E
Sbjct: 842 REYQERVKKLEEVE 855
Score = 45.4 bits (106), Expect = 5e-04
Identities = 56/211 (26%), Positives = 81/211 (38%), Gaps = 45/211 (21%)
Query: 1507 GDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQ 1566
GD P PW+ K ++++ K +E P S +R EW +
Sbjct: 1161 GDDSRPGPWRPLVKPGGWREKE--------KAREESWGPPRESRPSEER------EWDRE 1206
Query: 1567 KRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQL 1626
K + +D D EE D D + +R + +R R P +DE R+
Sbjct: 1207 KE----RDRDNQDREENDKDPERERDRER-DVDREDRFRRP--------RDEGGWRRGPA 1253
Query: 1627 EEMRK---------REAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAER--- 1674
EE R+ +DR R+ ++RR E R RD ++R G R E E
Sbjct: 1254 EESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRR----GPPLRSEREEVSS 1309
Query: 1675 -RRQHDEAARRLLEPEAPGLCRPP-LPRDYE 1703
RR D R+ E + P PP L RD E
Sbjct: 1310 WRRADDRKDDRVEERDPPRRVPPPALSRDRE 1340
Score = 35.8 bits (81), Expect = 0.39
Identities = 23/101 (22%), Positives = 53/101 (52%), Gaps = 6/101 (5%)
Query: 140 QSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQASDKDDRPF---QGEDVENSR 196
Q E +++E +Q ++ ++ ++E K+REKE + Q ++ + + E ++ +
Sbjct: 588 QREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTE 647
Query: 197 LAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFR 237
L A+ +KD+ +P+ +M ++ +Q LEK +E +
Sbjct: 648 LGAKAFKDIDIEDLEEL--DPDFIMAKQVEQ-LEKEKKELQ 685
Score = 33.9 bits (76), Expect = 1.5
Identities = 53/277 (19%), Positives = 101/277 (36%), Gaps = 52/277 (18%)
Query: 1425 LEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQ 1484
++++R +R + +R R P P+ PL KP + ++ P +
Sbjct: 1143 MDDDRLSRRADDDRF--PRRGDDSRPGPWRPLV-------KPGGWREKEKAREESWGPPR 1193
Query: 1485 QPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQS 1544
+ R E R+ +E+ D+ + +D + + ++++ + D + E
Sbjct: 1194 ESRPSEEREWD-----REKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGW 1248
Query: 1545 KPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRART 1604
+ + E S W+ R + +D DD E DD +R ERR
Sbjct: 1249 RRGPAEESSS--------WRDSSRRDD---RDRDDRRRERDD-------RRDLRERR--- 1287
Query: 1605 AMPAISVLDLLQDEERR------RQQQLEEMRKRE--AEDRARQEEERRRQEEERTKRDA 1656
DL D +RR ++++ R+ + +DR + + RR RD
Sbjct: 1288 --------DLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDR 1339
Query: 1657 EEKR-RQEEGYYSRLEAERRRQHDEAARRLLEPEAPG 1692
E R R+ EG + + + R E + G
Sbjct: 1340 ERDRDREREGEKEKASWRAEKDRESLRRTKNETDEDG 1376
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 77.0 bits (188), Expect = 2e-13
Identities = 126/553 (22%), Positives = 226/553 (40%), Gaps = 98/553 (17%)
Query: 1139 SPESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITS 1198
S SPQ+ +YS L + RA R + A +P + G ++ ++ +
Sbjct: 311 SSPSPQVLAQKYS----LVAKQESVVRRASRRLAKKTAEEPAASGRIICHSY--LERLLN 364
Query: 1199 VSTGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWP-NYEEKPHM 1257
V EQ PP EA P+ A++ + N WP N E +
Sbjct: 365 VEVPQKVGSEQKEPPE-EAEPVA------------AAEPEVPENNGNNSWPHNDTEIANS 411
Query: 1258 HTDSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSS 1317
+ ++ + + + Q+E + D+A R ++A ++S + S LD
Sbjct: 412 TPNPKPAASSPETPSAGQQEAKTDQA-DGPREPPQSARRKRS----YKQAVSELDE---- 462
Query: 1318 QEHLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPP--------PPPP 1369
++HL P R KTP++ P V +P+RT L P
Sbjct: 463 EQHLEDEELQ-----------PPRSKTPSS-PCPASKVVRPLRTFLHTVQRNQMLMTPTS 510
Query: 1370 PPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWY--EKEKARLEE 1427
P F + + PL P + + ++ R++ E R E++K R E
Sbjct: 511 APRSVMKSF--IKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLE 568
Query: 1428 ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPR 1487
E + KR E+ RK+ Q R + +QMK EK +++ + + + ++ R
Sbjct: 569 EVKLKREERLRKVLQARER-----------VEQMKEEKKKQIEQKFAQIDEKTEKAKEER 617
Query: 1488 TIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPD 1547
E + + K E + +R + E++++ H QEL K
Sbjct: 618 LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH---------QELLQK-- 666
Query: 1548 RSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMP 1607
+ EE +RLRK KRL E ++++ ++E + + +R E ERR +
Sbjct: 667 KKEEEQERLRKAAEA----KRLAEQREQERREQERREQERREQ---ERREQERREQERQ- 718
Query: 1608 AISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYY 1667
L ++ERRR+Q+ + +AE ++ E+ R ++E+ +R+ EEK+++EE
Sbjct: 719 -------LAEQERRREQE-----RLQAERELQEREKALRLQKEQLQRELEEKKKKEE--Q 764
Query: 1668 SRLEAERRRQHDE 1680
RL AER+ Q ++
Sbjct: 765 QRL-AERQLQEEQ 776
Score = 71.2 bits (173), Expect = 8e-12
Identities = 94/374 (25%), Positives = 155/374 (41%), Gaps = 93/374 (24%)
Query: 1343 KTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQ 1402
K A+ P TP A Q +TD D P PP SA
Sbjct: 416 KPAASSPETPSAGQQEAKTD-------------------QADGPREPPQSA--------- 447
Query: 1403 VAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMK 1462
RRKR Y++ + L+EE+ ++ +L R+++ P SP A
Sbjct: 448 -----RRKRS-----YKQAVSELDEEQHL----EDEELQPPRSKT----PSSPCPA---- 485
Query: 1463 PEKPSTLQRPQETVIRELQPQQQ---PRTIERRDLQYITVSKEELSSGDSLSPDP---WK 1516
S + RP T + +Q Q P + R +V K + L DP +
Sbjct: 486 ----SKVVRPLRTFLHTVQRNQMLMTPTSAPR------SVMKSFIKRNTPLRMDPKCSFV 535
Query: 1517 RDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEE-----SDRLRKLMLEWQFQKRLQE 1571
+++LE ++ + L + Q+++ R EE +RLRK++ + ++++E
Sbjct: 536 EKERQRLENLRRKEEAEQLRR--QKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKE 593
Query: 1572 SKQKDEDDEEEEDDDVDTMLIMQRL---------------EAERRARTAMPAISVLDLLQ 1616
K+K + + + D+ +RL E E R + A + L Q
Sbjct: 594 EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 653
Query: 1617 DEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRR 1676
+EE RR Q+L + +K E ++R R+ E +R E+R + E++RR++E R E ERR
Sbjct: 654 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE----RREQERRE 709
Query: 1677 Q-HDEAARRLLEPE 1689
Q E R+L E E
Sbjct: 710 QERREQERQLAEQE 723
Score = 35.8 bits (81), Expect = 0.39
Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 1407 ERRKREEHQRWYEK-EKARLEEERE----RKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
E+ +RE+ +R E+ E+ R E+ER+ +RREQER + Q A Q
Sbjct: 694 EQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQR 753
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIE 1490
+ E+ + Q R+LQ +Q+ + E
Sbjct: 754 ELEEKKKKEEQQRLAERQLQEEQEKKAKE 782
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 76.6 bits (187), Expect = 2e-13
Identities = 126/551 (22%), Positives = 225/551 (40%), Gaps = 98/551 (17%)
Query: 1139 SPESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITS 1198
S SPQ+ +YS L + RA R + A +P + G ++ ++ +
Sbjct: 311 SSPSPQVLAQKYS----LVAKQESVVRRASRRLAKKTAEEPAASGRIICHSY--LERLLN 364
Query: 1199 VSTGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWP-NYEEKPHM 1257
V EQ PP EA P+ A++ + N WP N E +
Sbjct: 365 VEVPQKVGSEQKEPPE-EAEPVA------------AAEPEVPENNGNNSWPHNDTEIANS 411
Query: 1258 HTDSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSS 1317
+ ++ + + + Q+E + D+A R ++A ++S + S LD
Sbjct: 412 TPNPKPAASSPETPSAGQQEAKTDQA-DGPREPPQSARRKRS----YKQAVSELDE---- 462
Query: 1318 QEHLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPP--------PPPP 1369
++HL P R KTP++ P V +P+RT L P
Sbjct: 463 EQHLEDEELQ-----------PPRSKTPSS-PCPASKVVRPLRTFLHTVQRNQMLMTPTS 510
Query: 1370 PPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEER 1429
P F + L + P Q + AE+ +R++ E++K R EE
Sbjct: 511 APRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQK----VEEDKRRRLEEV 566
Query: 1430 ERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTI 1489
+ KR E+ RK+ Q R + +QMK EK +++ + + + ++ R
Sbjct: 567 KLKREERLRKVLQARER-----------VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLA 615
Query: 1490 ERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRS 1549
E + + K E + +R + E++++ H QEL K +
Sbjct: 616 EEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH---------QELLQK--KK 664
Query: 1550 AEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAI 1609
EE +RLRK KRL E ++++ ++E + + +R E ERR +
Sbjct: 665 EEEQERLRKAAEA----KRLAEQREQERREQERREQERREQ---ERREQERREQERQ--- 714
Query: 1610 SVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSR 1669
L ++ERRR+Q+ + +AE ++ E+ R ++E+ +R+ EEK+++EE R
Sbjct: 715 -----LAEQERRREQE-----RLQAERELQEREKALRLQKEQLQRELEEKKKKEE--QQR 762
Query: 1670 LEAERRRQHDE 1680
L AER+ Q ++
Sbjct: 763 L-AERQLQEEQ 772
Score = 74.3 bits (181), Expect = 1e-12
Identities = 95/371 (25%), Positives = 155/371 (41%), Gaps = 91/371 (24%)
Query: 1343 KTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQ 1402
K A+ P TP A Q +TD D P PP SA
Sbjct: 416 KPAASSPETPSAGQQEAKTD-------------------QADGPREPPQSA--------- 447
Query: 1403 VAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMK 1462
RRKR Y++ + L+EE+ ++ +L R+++ P SP A
Sbjct: 448 -----RRKRS-----YKQAVSELDEEQHL----EDEELQPPRSKT----PSSPCPA---- 485
Query: 1463 PEKPSTLQRPQETVIRELQPQQQ---PRTIERRDLQYITVSKEELSSGDSLSPDPWKRDA 1519
S + RP T + +Q Q P + R +V K + L DP K
Sbjct: 486 ----SKVVRPLRTFLHTVQRNQMLMTPTSAPR------SVMKSFIKRNTPLRMDP-KEKE 534
Query: 1520 KEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEE-----SDRLRKLMLEWQFQKRLQESKQ 1574
+++LE ++ + L + Q+++ R EE +RLRK++ + ++++E K+
Sbjct: 535 RQRLENLRRKEEAEQLRR--QKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKK 592
Query: 1575 KDEDDEEEEDDDVDTMLIMQRL---------------EAERRARTAMPAISVLDLLQDEE 1619
K + + + D+ +RL E E R + A + L Q+EE
Sbjct: 593 KQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE 652
Query: 1620 RRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQ-H 1678
RR Q+L + +K E ++R R+ E +R E+R + E++RR++E R E ERR Q
Sbjct: 653 ERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE----RREQERREQER 708
Query: 1679 DEAARRLLEPE 1689
E R+L E E
Sbjct: 709 REQERQLAEQE 719
Score = 35.8 bits (81), Expect = 0.39
Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 1407 ERRKREEHQRWYEK-EKARLEEERE----RKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
E+ +RE+ +R E+ E+ R E+ER+ +RREQER + Q A Q
Sbjct: 690 EQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQR 749
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIE 1490
+ E+ + Q R+LQ +Q+ + E
Sbjct: 750 ELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 75.9 bits (185), Expect = 3e-13
Identities = 61/296 (20%), Positives = 142/296 (47%), Gaps = 24/296 (8%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1466
E+ +R+E W ++EK R +EE ++ E+ R+L +M + + + +
Sbjct: 335 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIRE 394
Query: 1467 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAK------ 1520
+R +E IRE + +Q+ R + I +E++ + W+++ K
Sbjct: 395 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM---WRQEEKIHEQEK 451
Query: 1521 ----EKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKD 1576
EK ++Q++M + +E +E+ + ++ E+ ++ W+ ++++ + ++K
Sbjct: 452 IREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKI 511
Query: 1577 EDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLD-LLQDEERRRQQQLEEMRKREAE 1635
+ EE+ + + E E + R I + ++Q++E + +Q E+M+++E
Sbjct: 512 REQEEKMWRQEEKIR-----EQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE-- 564
Query: 1636 DRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQH--DEAARRLLEPE 1689
+ R++EE+ R++EE+ + E+ R QEE + + E R ++ E ++ E E
Sbjct: 565 -KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE 619
Score = 75.1 bits (183), Expect = 6e-13
Identities = 63/293 (21%), Positives = 149/293 (50%), Gaps = 23/293 (7%)
Query: 1407 ERRKREEHQRWYEKEKAR-LEE---ERERKRREQERKLGQ---MRTQSLNPAPFSPLTAQ 1459
E+ +R+E W ++EK R LEE E+E K RE E K+ + +R Q + Q
Sbjct: 349 EKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 408
Query: 1460 QMKPEKPSTLQRPQETVIRELQPQ--QQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR 1517
+ + E+ + + R QE IRE + + +Q + + R++ + K + W++
Sbjct: 409 EKRQEQEAKMWR-QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ 467
Query: 1518 DAK-----EKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLE-WQFQKRLQE 1571
+ K E ++++MH + + K+ +++ + ++ ++ +++R+ + W+ +++++E
Sbjct: 468 EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE 527
Query: 1572 SKQKDEDDEEEEDDDVDTMLIMQRL--EAERRARTAMPAISVLDLLQDEERRRQQQLEEM 1629
++K + EE+ + + M + E E + + + ++++E + ++Q E++
Sbjct: 528 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587
Query: 1630 RKREA-----EDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQ 1677
R++E E++ R++EE +++EE+ E+ QEE + E RR++
Sbjct: 588 REQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 640
Score = 67.8 bits (164), Expect = 9e-11
Identities = 60/289 (20%), Positives = 141/289 (48%), Gaps = 32/289 (11%)
Query: 1409 RKREEHQRWYEKEKARLEE--ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1466
R+ E+ Q W EK + + E+ E+E K REQE K MR Q ++M EK
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK---MRRQ------------EEMMWEKE 348
Query: 1467 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQ 1526
++R +E + + + ++ + + I +E++ + + KR +EK+ +Q
Sbjct: 349 EKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 408
Query: 1527 QQMHIVD-MLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDD-----E 1580
++ + + ++ ++++ + ++ E+ ++ + + Q++++E +++ E + E
Sbjct: 409 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 468
Query: 1581 EEEDDDVDTMLIMQRLEAERRARTAMPAI-SVLDLLQDEERRRQQQLEEM-----RKREA 1634
E+ + + +++ + + R + + + D+E + ++Q E+M + RE
Sbjct: 469 EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQ 528
Query: 1635 EDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAAR 1683
E++ R++EE+ R++EE + E+ QEE E E+ R+ +E R
Sbjct: 529 EEKIREQEEKIREQEEMMQEQEEKMGEQEE---KMQEQEKMRRQEEKIR 574
Score = 64.7 bits (156), Expect = 8e-10
Identities = 59/295 (20%), Positives = 142/295 (48%), Gaps = 46/295 (15%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEE--RERKRREQERKLGQMRTQSLNPAPFSPLTAQ 1459
++ E + E+ + ++EK + EE+ + KR+EQE K+ + + + Q
Sbjct: 378 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK---------IREQ 428
Query: 1460 QMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDA 1519
+ K + QE I E Q++ R E+R Q +EE R+
Sbjct: 429 EEKIREQEKKMWRQEEKIHE---QEKIREEEKRQEQEEMWRQEEKI-----------REQ 474
Query: 1520 KEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLE-WQFQKRLQESKQKDED 1578
+E ++++MH + + K+ +++ + ++ ++ +++R+ + W+ +++++E ++K +
Sbjct: 475 EEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIRE 534
Query: 1579 DEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQ----LEEMRKREA 1634
EE+ + + M + E+ + +Q++E+ R+Q+ +E + RE
Sbjct: 535 QEEKIREQEEMMQEQEEKMGEQEEK-----------MQEQEKMRRQEEKIREQEEKIREQ 583
Query: 1635 EDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLE-----AERRRQHDEAARR 1684
+++ R++EE+ ++EE+ + E + QEE + + E E+ ++ +E RR
Sbjct: 584 KEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 638
Score = 63.2 bits (152), Expect = 2e-09
Identities = 57/289 (19%), Positives = 135/289 (46%), Gaps = 9/289 (3%)
Query: 1398 LPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLT 1457
LP Q+ A +E Q K +A++EE R Q+++ R + +
Sbjct: 258 LPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ 317
Query: 1458 AQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR 1517
Q+ K + R QE +R + + + R + + KEE L W++
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR--RLEEMMWEK 375
Query: 1518 DAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDE 1577
+ K + E +++MH + + +E +E + + ++ E+ R + W+ +++++E ++K
Sbjct: 376 EEKIR-ELEEKMHEQEKI-REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
Query: 1578 DDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEE---RRRQQQLEEMRKREA 1634
+ E++ + + +++ E + + + ++++E R++++ E+ + R+
Sbjct: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 1635 EDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAAR 1683
E++ ++EE+ +EE+ + E+ RQEE R + E+ R+ +E R
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI--REQEEKIREQEEKIR 540
Score = 55.1 bits (131), Expect = 6e-07
Identities = 62/242 (25%), Positives = 115/242 (47%), Gaps = 45/242 (18%)
Query: 1467 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK---------- 1516
+T ++ + I EL ++ ++E L T++ EEL ++ + +
Sbjct: 185 ATQKKKADRYIEELTKERDALSLE---LYRNTITDEELKEKNAKLQEKLQLVESEKSEIQ 241
Query: 1517 ---RDAKEKLEK------QQQMHI-VDMLSKEIQELQSKPDRSAEESDRLRKLMLE---- 1562
++ K KLE+ QQQ+ D L KE+Q + +K EE++ +L +
Sbjct: 242 LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK 301
Query: 1563 -WQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERR 1621
W+ ++++QE ++K ++ EE+ + + I ++ E RR M + EE+
Sbjct: 302 MWRQEEKIQEWEEKIQEQEEKIREQEEK--IREQEEKMRRQEEMM--------WEKEEKM 351
Query: 1622 RQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEA 1681
R+Q EEM E E++ R+ EE ++EE+ R+ EEK ++E E E +RQ +E
Sbjct: 352 RRQ--EEMMW-EKEEKMRRLEEMMWEKEEKI-RELEEKMHEQE---KIREQEEKRQEEEK 404
Query: 1682 AR 1683
R
Sbjct: 405 IR 406
Score = 54.7 bits (130), Expect = 8e-07
Identities = 57/280 (20%), Positives = 133/280 (47%), Gaps = 29/280 (10%)
Query: 1410 KREEHQRWYEKEKARLE-EERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPST 1468
K +E + E EK+ ++ +E KR+ + KL L QQ +
Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRKLERAKL---------------LLPQQQLQAEADH 269
Query: 1469 LQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQ 1528
L + ++V +LQ Q + + R + +EE W+ +E+ EK ++
Sbjct: 270 LGKELQSVSAKLQAQVEENELWNR----LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 325
Query: 1529 MHIVDMLSKEIQELQSKPDRSAEESDRLRKLM-LEWQFQKRLQESKQKDEDDEEEEDDDV 1587
+ + ++ ++++ + + E+ +++R+ + W+ +++++ ++ + EE+ +
Sbjct: 326 QE--EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELE 383
Query: 1588 DTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQ 1647
+ M +++ + R I + Q++E + +Q E++R++E + R QE++ RQ
Sbjct: 384 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR-EQEKKMWRQ 442
Query: 1648 EE---ERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARR 1684
EE E+ K EEKR+++E + + E+ R+ +E R+
Sbjct: 443 EEKIHEQEKIREEEKRQEQEEMWR--QEEKIREQEEIWRQ 480
Score = 52.0 bits (123), Expect = 5e-06
Identities = 65/253 (25%), Positives = 121/253 (47%), Gaps = 38/253 (15%)
Query: 1473 QETVIRELQPQQQP---RTIERRDLQYI------TVSKEELSSGDSLSP--DPWK--RDA 1519
QE + REL+ Q T ++ +LQ V + E + D +S D WK +
Sbjct: 118 QEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGEL 177
Query: 1520 KEKL-----EKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESK- 1573
++ L +K++ ++ L+KE L + R+ + L++ + Q + +L ES+
Sbjct: 178 EQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEK 237
Query: 1574 ---QKDEDDEEEEDDDVDTMLIMQRLEAER-RARTAMPAISVLDLLQDEE-----RRRQQ 1624
Q + + + + + +L Q+L+AE + ++S Q EE R QQ
Sbjct: 238 SEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQ 297
Query: 1625 QLEEMRKREA-----EDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQH- 1678
Q E+M ++E E++ +++EE+ R++EE+ + E+ RRQEE + + E RR++
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM 357
Query: 1679 ----DEAARRLLE 1687
+E RRL E
Sbjct: 358 MWEKEEKMRRLEE 370
Score = 43.5 bits (101), Expect = 0.002
Identities = 35/176 (19%), Positives = 82/176 (46%), Gaps = 19/176 (10%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1466
E+ + +E + W ++EK R E+E K REQE K+ + + + + Q+ K ++
Sbjct: 509 EKIREQEEKMWRQEEKIR---EQEEKIREQEEKIREQ--EEMMQEQEEKMGEQEEKMQEQ 563
Query: 1467 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQ 1526
++R +E + + + ++ + R + I +E++ + + ++ +EK+ +Q
Sbjct: 564 EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMM-----QEQEEKMWEQ 618
Query: 1527 QQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEE 1582
++ ++ E + K E+ R + M E + + R QE K ++ + E
Sbjct: 619 EE---------KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 75.5 bits (184), Expect = 4e-13
Identities = 69/314 (21%), Positives = 153/314 (48%), Gaps = 47/314 (14%)
Query: 1407 ERRKREEHQRWYEKEKARLEEE----RERKRREQERKLGQ---MRTQSLNPAPFSPLTAQ 1459
E+ +R+E W ++EK R +EE +E K RE E K+ + +R Q + Q
Sbjct: 363 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 422
Query: 1460 QMKPEKPSTLQRPQETV------IRE-----------LQPQQQPRTIERRDLQYITVSKE 1502
+ + E+ + + R +E + IRE + Q++ R E+R Q +E
Sbjct: 423 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 482
Query: 1503 ELSSGDSLSPDPWKRDAK-----EKLEKQQQM--HIVDMLSKEIQELQSKPDRSAEESDR 1555
E + W++ K EK+ KQ++ + + ++ ++++ + ++ + ++
Sbjct: 483 EKIHEQE---EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEK 539
Query: 1556 LRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLL 1615
+R+ W+ ++++ E ++ E+++ +E +D M R E + R + + +
Sbjct: 540 IREQEEMWREEEKMHEQEKIWEEEKRQEQEDK-----MWRQEEKIREQEEK-VWRQEEKI 593
Query: 1616 QDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERR 1675
+++E +RQ+Q E+M K+ E++ R++EE+ +++EE+ + E+ R QEE + E+
Sbjct: 594 REQEEKRQEQEEKMWKQ--EEKIREQEEKIQEQEEKIREQEEKIREQEE-----MTQEQE 646
Query: 1676 RQHDEAARRLLEPE 1689
+ E ++ E E
Sbjct: 647 EKMGEQEEKMCEQE 660
Score = 71.6 bits (174), Expect = 6e-12
Identities = 53/284 (18%), Positives = 141/284 (49%), Gaps = 35/284 (12%)
Query: 1407 ERRKREEHQRWYEKEKARLEEE---RERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKP 1463
E +++E+ + W ++EK +EE ++ K EQE K+ + Q+ K
Sbjct: 469 EEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRK----------------QEEKV 512
Query: 1464 EKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKL 1523
+ R QE IRE + + + + R+ + + +E++ + + + +++ ++K+
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKM 572
Query: 1524 EKQQQM--HIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEE 1581
+Q++ + + ++ ++++ + ++ E+ +++ W+ +++++E ++K ++ EE
Sbjct: 573 WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM------WKQEEKIREQEEKIQEQEE 626
Query: 1582 ---EEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRK-----RE 1633
E+++ + M + + E+ + +Q++E +Q E++R+ RE
Sbjct: 627 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIRE 686
Query: 1634 AEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQ 1677
E++ R++EE +++EE+ E+ QEE + E RR++
Sbjct: 687 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
Score = 67.4 bits (163), Expect = 1e-10
Identities = 63/295 (21%), Positives = 137/295 (46%), Gaps = 33/295 (11%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
++ E+R+ +E + W ++EK R E+E K REQE+K+ + + +Q
Sbjct: 418 KIREQEKRQEQEAKMWRQEEKIR---EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 474
Query: 1462 KPE--KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDP----W 1515
+ E + QE + R+ + + R+ + + +E++ + + W
Sbjct: 475 QEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMW 534
Query: 1516 KRDAK-----EKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLE-WQFQKRL 1569
+++ K E ++++MH + + +E ++ Q + D+ + +++R+ + W+ ++++
Sbjct: 535 RQEEKIREQEEMWREEEKMHEQEKIWEE-EKRQEQEDKMWRQEEKIREQEEKVWRQEEKI 593
Query: 1570 QESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEM 1629
+E ++K ++ EE+ M + E + R + + + EE+ R+Q EEM
Sbjct: 594 REQEEKRQEQEEK----------MWKQEEKIREQEEKIQEQEEKIREQEEKIREQ--EEM 641
Query: 1630 RKREAEDRARQEE-----ERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHD 1679
+ + E QEE E + QE+E T EEK R++E E + R Q +
Sbjct: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
Score = 66.2 bits (160), Expect = 3e-10
Identities = 59/287 (20%), Positives = 140/287 (48%), Gaps = 33/287 (11%)
Query: 1409 RKREEHQRWYEKEKARLEE--ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1466
R+ E+ Q W EK + + E+ E+E K REQE K MR Q ++M EK
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK---MRRQ------------EEMMWEKE 348
Query: 1467 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQ 1526
++R +E + + + RR + + +E++ + + W+++ K + E +
Sbjct: 349 EKMRRQEEMMWEKEEKM-------RRQEEMMWEKEEKMRRQEEMM---WEKEEKIR-ELE 397
Query: 1527 QQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDD 1586
++MH + + +E +E + + ++ E+ R + W+ +++++E ++K + E++
Sbjct: 398 EKMHEQEKI-REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 456
Query: 1587 VDTMLIMQRLEAERRARTAMPAISVLDLLQDEER--RRQQQLEEMRK--REAEDRARQEE 1642
+ + +++ E + + + + ++E R+++++ E + R+ E++ ++E
Sbjct: 457 EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE 516
Query: 1643 ERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
E+ R++EE+ + E+ RQEE + E R + ++ E E
Sbjct: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE 563
Score = 66.2 bits (160), Expect = 3e-10
Identities = 60/261 (22%), Positives = 126/261 (48%), Gaps = 20/261 (7%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1466
E+ +++E + W ++EK R E+E K REQE K+ + + +Q + +
Sbjct: 503 EKIRKQEEKVWRQEEKIR---EQEEKIREQEEKMWRQEEK----------IREQEEMWRE 549
Query: 1467 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR-DAKEKLEK 1525
QE + E + Q+Q + R++ + ++ + + KR + +EK+ K
Sbjct: 550 EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK 609
Query: 1526 QQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDD 1585
Q++ + ++IQE + K R EE R ++ M + Q ++++ E ++K + EE+ +
Sbjct: 610 QEEK--IREQEEKIQEQEEKI-REQEEKIREQEEMTQEQ-EEKMGEQEEKMCEQEEKMQE 665
Query: 1586 DVDTMLIMQRL--EAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEE 1643
+TM + E E++ R I + + E+ + + EE + E QEE+
Sbjct: 666 QEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 725
Query: 1644 RRRQEEERTKRDAEEKRRQEE 1664
RRQEE+ +++ ++++E+
Sbjct: 726 MRRQEEKMWEQEVRLRQQEEK 746
Score = 65.9 bits (159), Expect = 4e-10
Identities = 60/285 (21%), Positives = 136/285 (47%), Gaps = 32/285 (11%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRRE----QERKLGQMRTQSLNPAPFSPLTAQQMK 1462
E + E+ + W +KEK +EE+ RK+ E QE K+ + + + Q+ K
Sbjct: 482 EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEK---------IREQEEK 532
Query: 1463 PEKPSTLQRPQETVIRELQPQQQPRTI---ERRDLQYITVSKEELSSGDSLSPDPWKRDA 1519
+ R QE + RE + + I E+R Q + ++E + W+++
Sbjct: 533 MWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQ-EEKVWRQEE 591
Query: 1520 KEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDD 1579
K + +++++ + + K+ ++++ + ++ E+ +++R+ +++++E ++ ++
Sbjct: 592 KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQ------EEKIREQEEMTQEQ 645
Query: 1580 EEEEDDDVDTMLIMQRLEAERRARTAMPAISVLD----LLQDEERRRQQQLEEMRKREAE 1635
EE+ + + M + E+ + + + + EE+ R+Q EEM + + E
Sbjct: 646 EEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ--EEMMQEQEE 703
Query: 1636 DRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDE 1680
QEE+ QEE+ +++ E+ RRQEE + + R RQ +E
Sbjct: 704 KMWEQEEKMCEQEEKMQEQE-EKMRRQEEKMWE--QEVRLRQQEE 745
Score = 63.9 bits (154), Expect = 1e-09
Identities = 68/296 (22%), Positives = 140/296 (47%), Gaps = 45/296 (15%)
Query: 1393 ANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAP 1452
A+ +G V+A + + EE++ W RL +++E K QE K+ +
Sbjct: 267 ADHLGKELQSVSAKLQAQVEENELWN-----RLNQQQEEKMWRQEEKIQEW--------- 312
Query: 1453 FSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSP 1512
+ K ++ R QE IRE + + RR + + +E++ + +
Sbjct: 313 -------EEKIQEQEEKIREQEEKIREQEEKM------RRQEEMMWEKEEKMRRQEEMM- 358
Query: 1513 DPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRL--Q 1570
W+++ EK+ +Q++M M KE ++++ + + E+ +++R+L + Q+++ Q
Sbjct: 359 --WEKE--EKMRRQEEM----MWEKE-EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 409
Query: 1571 ESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQ--LEE 1628
E K+++E+ E++ + M R E + R + + + EE+ +Q+ EE
Sbjct: 410 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE 469
Query: 1629 MRKREAEDRARQEEERRRQEE----ERTKRDAEEKRRQEEGYYSRLEAERRRQHDE 1680
+++E E+ RQEE+ QEE + + EEK R++E R E + R Q ++
Sbjct: 470 EKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEK 525
Score = 61.2 bits (147), Expect = 9e-09
Identities = 64/251 (25%), Positives = 118/251 (47%), Gaps = 49/251 (19%)
Query: 1467 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK---------- 1516
+T ++ + I EL ++ ++E L T++ EEL ++ + +
Sbjct: 185 ATQKKKADRYIEELTKERDALSLE---LYRNTITDEELKEKNAKLQEKLQLVESEKSEIQ 241
Query: 1517 ---RDAKEKLEK------QQQMHI-VDMLSKEIQELQSKPDRSAEESDRLRKLMLE---- 1562
++ K KLE+ QQQ+ D L KE+Q + +K EE++ +L +
Sbjct: 242 LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK 301
Query: 1563 -WQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERR 1621
W+ ++++QE ++K ++ EE+ + + I ++ E RR M ++E+ R
Sbjct: 302 MWRQEEKIQEWEEKIQEQEEKIREQEEK--IREQEEKMRRQEEMMWE-------KEEKMR 352
Query: 1622 RQQQL----EEMRKREAEDRARQEEERRRQEE-----ERTKRDAEEKRRQEEGYYSRLEA 1672
RQ+++ EE +R+ E +EE+ RRQEE E R+ EEK ++E E
Sbjct: 353 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE---KIREQ 409
Query: 1673 ERRRQHDEAAR 1683
E +RQ +E R
Sbjct: 410 EEKRQEEEKIR 420
Score = 57.4 bits (137), Expect = 1e-07
Identities = 55/285 (19%), Positives = 134/285 (47%), Gaps = 38/285 (13%)
Query: 1410 KREEHQRWYEKEKARLE-EERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPST 1468
K +E + E EK+ ++ +E KR+ + KL L QQ +
Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRKLERAKL---------------LLPQQQLQAEADH 269
Query: 1469 LQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQ 1528
L + ++V +LQ Q + + R + +EE W+ +E+ EK ++
Sbjct: 270 LGKELQSVSAKLQAQVEENELWNR----LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 325
Query: 1529 MHIVDMLSKEIQELQSKPDRSAEESDRLRK---LMLEWQFQKRLQESKQKDEDDEEEEDD 1585
+ + ++ ++++ + + E+ +++R+ +M E + + R QE +++++ +
Sbjct: 326 QE--EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 383
Query: 1586 DVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQ---LEEMRKREAEDRARQEE 1642
++ E E + R + + ++++E +RQ++ E+ +++E E + ++E
Sbjct: 384 EM-------MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Query: 1643 ERRRQEEERTKRDAEEKRRQEEGYYSR---LEAERRRQHDEAARR 1684
E+ R++EE+ + ++ RQEE + + E E+R++ +E R+
Sbjct: 437 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ 481
Score = 52.0 bits (123), Expect = 5e-06
Identities = 56/270 (20%), Positives = 119/270 (44%), Gaps = 19/270 (7%)
Query: 1419 EKEKARLEEERERKRREQERKLGQMR------TQSLNPAPFSPLTAQQMKPEKPSTLQRP 1472
E E+ + +E RRE E ++ +R T+ +S +Q++ E + R
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 1473 QETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR-----DAKEKLEKQQ 1527
++ + +Q + + + +E D+LS + ++ + KEK K Q
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 1528 QMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDV 1587
+ + ++ E E+Q + +R + L+ + Q Q ++ + + V
Sbjct: 228 EK--LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
Query: 1588 DTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQ 1647
+ + RL ++ + + +Q+ E + Q+Q E++R E E++ R++EE+ R+
Sbjct: 286 EENELWNRLNQQQEEKMWRQE----EKIQEWEEKIQEQEEKIR--EQEEKIREQEEKMRR 339
Query: 1648 EEERTKRDAEEKRRQEEGYYSRLEAERRRQ 1677
+EE E+ RRQEE + + E RR++
Sbjct: 340 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 369
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 75.5 bits (184), Expect = 4e-13
Identities = 66/291 (22%), Positives = 139/291 (47%), Gaps = 49/291 (16%)
Query: 1402 QVAAAERRKREEHQR-WYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQ 1460
Q+ E++ R++ +R W + E+ R +EER R++ + ++ +MR ++
Sbjct: 384 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMR--------------EE 429
Query: 1461 MKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAK 1520
K ++ R QE ++Q +++ R E++ + +E+ + W+++ K
Sbjct: 430 KKMQEQEKKTRDQE---EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 486
Query: 1521 EKLEKQQQMHIVDMLSK--EIQELQSKPDRSAEESDRLRKLMLEWQFQKRL--QESKQKD 1576
E QQ + + K E +++Q + ++ E+ +++R W +K++ QE ++
Sbjct: 487 E----WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542
Query: 1577 ED---DEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRK-- 1631
ED ++EE+ D + + Q E++ Q++E++ Q E+MR+
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKKT-------------QEQEKKTWDQEEKMREEE 589
Query: 1632 --REAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDE 1680
RE E + R+EEE R++EE+ + E+ + QEE + E E + Q E
Sbjct: 590 RMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMW---EQEEKMQEQE 637
Score = 75.1 bits (183), Expect = 6e-13
Identities = 61/291 (20%), Positives = 132/291 (45%), Gaps = 29/291 (9%)
Query: 1407 ERRKREEHQRWYEKEKA----RLEEERER-----KRREQERKLGQMRTQSLNPAPFSPLT 1457
E+ +++E W ++EK RL E++E+ K +EQE K+ + + +
Sbjct: 471 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE 530
Query: 1458 AQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR 1517
+ + EK +RE + Q + + RD + +EE + +
Sbjct: 531 KKMWRQEK-----------MREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTW 579
Query: 1518 DAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLE--WQFQKRLQESKQK 1575
D +EK+ ++++M + +E +E+ + + +E + + E W+ ++++QE ++K
Sbjct: 580 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEK 639
Query: 1576 DEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAE 1635
+ EE+ + + M QRL ++ + + +Q++E + +Q E+M K+ E
Sbjct: 640 MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQ-EKMEKKTQE 698
Query: 1636 ------DRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDE 1680
D+ + EE +E E+ R+ EE R++E E + + Q +E
Sbjct: 699 QEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEE 749
Score = 71.2 bits (173), Expect = 8e-12
Identities = 54/278 (19%), Positives = 138/278 (49%), Gaps = 45/278 (16%)
Query: 1413 EHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRP 1472
+ + W ++E+ R E+E+K R+QE K+ + + L Q+ K +
Sbjct: 271 QEEMWRQEEELR---EQEKKIRKQEEKMWRQEER---------LREQEGKMREQEEKMWR 318
Query: 1473 QETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIV 1532
QE +RE + + + + E R+ + + +E++ + W+++ K + ++++
Sbjct: 319 QEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKM---WEQEEKMREQEEKMWRQE 375
Query: 1533 DMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLI 1592
+ L ++ ++++ + + ++ +R+ W+ +RL+E +++ + E+ +
Sbjct: 376 ERLWEQEKQMREQEQKMRDQEERM------WEQDERLREKEERMREQEKMWEQ------- 422
Query: 1593 MQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERT 1652
++++ E++ +Q++E++ + Q E+M++ E+R R+ E++ R+EEE
Sbjct: 423 VEKMREEKK-------------MQEQEKKTRDQEEKMQE---EERIREREKKMREEEETM 466
Query: 1653 KRDAEEKRRQEEGYYSRLEAERRRQH-DEAARRLLEPE 1689
+ E+ ++QEE + + E E ++Q E +L E E
Sbjct: 467 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 504
Score = 68.9 bits (167), Expect = 4e-11
Identities = 56/278 (20%), Positives = 133/278 (47%), Gaps = 15/278 (5%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKR-----------REQERKLGQMRTQSLNPAPFSP 1455
E++ +E+ ++ +++E+ EEER R+R REQE K+ + +
Sbjct: 568 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMW 627
Query: 1456 LTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPW 1515
++M+ ++ ++ ++ +E + +Q R E+++ + +E W
Sbjct: 628 EQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIW 687
Query: 1516 KRDAKEKLEKQQQMHIVDMLS-KEIQELQSKPDRSAEESDRLRKLMLEWQFQK-RLQESK 1573
+++ EK ++Q+ D +E + ++ + + EE + +R+ + Q Q+ ++QE +
Sbjct: 688 EQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 747
Query: 1574 QKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKRE 1633
++ + EE+ + + M QRL ++ + + + ++E + + Q E+MR +E
Sbjct: 748 EEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE 807
Query: 1634 AEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLE 1671
++ R +EE+ R +EE+ E+ QEE + + E
Sbjct: 808 --EKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE 843
Score = 68.6 bits (166), Expect = 5e-11
Identities = 68/282 (24%), Positives = 130/282 (46%), Gaps = 35/282 (12%)
Query: 1407 ERRKREEHQRWYEKEKARLEE---ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKP 1463
++ + +E + W ++EK R EE ERE+K RE+E + + + + Q+ K
Sbjct: 569 KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE--EKMQEQEEKM 626
Query: 1464 EKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKL 1523
+ + QE + E + + + + + Q + KE+L + + ++ +EK+
Sbjct: 627 WEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKI 686
Query: 1524 EKQQQMHIVDMLSKEIQELQSKP----DRSAEESDRLR-KLMLEWQFQKRLQESKQKDED 1578
+Q++M K+ QE + K EES R R K M E + R QE K ++++
Sbjct: 687 WEQEKME------KKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQE 740
Query: 1579 DEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRA 1638
++ +E ++ + E E + Q+E+ QQ+L E +++ E
Sbjct: 741 EKMQEQEE-------EMWEQEEKMWE-----------QEEKMWEQQRLPEQKEKLWEHEK 782
Query: 1639 RQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDE 1680
QE+E+ ++EE+ RD EEK R +E E + R Q ++
Sbjct: 783 MQEQEKIWEQEEK-MRDQEEKMRGQEEKMRGQEEKMRGQEEK 823
Score = 65.9 bits (159), Expect = 4e-10
Identities = 52/275 (18%), Positives = 133/275 (48%), Gaps = 16/275 (5%)
Query: 1407 ERRKREEHQRWYEKEK--ARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPE 1464
+ R RE+ +R E+EK ++E+ RE K+ +++ K + R Q + ++ K
Sbjct: 403 DERLREKEERMREQEKMWEQVEKMREEKKMQEQEK--KTRDQEEKMQEEERIREREKKMR 460
Query: 1465 KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK-RDAKEKL 1523
+ R QE +++ + + + Q + KE+L + + K + +EK+
Sbjct: 461 EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 520
Query: 1524 EKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLR-KLMLEWQFQKRLQESKQKDEDDEEE 1582
Q++M + ++++ + D+ E+ +++R + W ++R+++ Q+ E +
Sbjct: 521 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD 580
Query: 1583 EDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEE 1642
+++ + M+ E + R ++++++E + Q+Q E+M +E E++ ++E
Sbjct: 581 QEEKMREEERMREREKKMREEE--------EMMREQEEKMQEQEEKM--QEQEEKMWEQE 630
Query: 1643 ERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQ 1677
E+ +++EE+ E+ QEE + + +++
Sbjct: 631 EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKE 665
Score = 65.5 bits (158), Expect = 5e-10
Identities = 61/292 (20%), Positives = 138/292 (47%), Gaps = 23/292 (7%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQ----MRTQSLNPAPFSPLTAQQMK 1462
E++ R++ ++ E+E+ R ERE+K RE+E + + M+ Q N QQ +
Sbjct: 436 EKKTRDQEEKMQEEERIR---EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 492
Query: 1463 -PEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDP---WKRD 1518
PE+ L ++ +E + +Q I RD + + ++++ + + W+++
Sbjct: 493 LPEQKEKLWEQEKMQEQEEKIWEQEEKI--RDQEEMWGQEKKMWRQEKMREQEDQMWEQE 550
Query: 1519 AKEKLEKQQQMHIVDMLSKEIQELQSKP---DRSAEESDRLR---KLMLEWQFQKRLQES 1572
K + ++Q+ + + K+ QE + K + E +R+R K M E + R QE
Sbjct: 551 EKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEE 610
Query: 1573 KQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKR 1632
K ++++++ +E ++ + ++ E + M Q+E+ QQ+L E +++
Sbjct: 611 KMQEQEEKMQEQEEK----MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEK 666
Query: 1633 EAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARR 1684
E QE+E+ +++EE+ + +++ +E + E+ R+ + R
Sbjct: 667 LWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRER 718
Score = 60.8 bits (146), Expect = 1e-08
Identities = 66/304 (21%), Positives = 135/304 (44%), Gaps = 27/304 (8%)
Query: 1410 KREEHQRWYEKEKARLEE----ERERKRREQERKLGQ----MRTQSLNPAPFSPLTAQQM 1461
+++E + W ++E+ R +E E+E K QE++L + +R Q L Q+
Sbjct: 289 RKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEE 348
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDS----LSPDPWKR 1517
+ ++ QE +RE Q ++ R ER Q + ++E D D R
Sbjct: 349 QMQEQEEKMWEQEEKMRE-QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLR 407
Query: 1518 DAKEKLEKQQQM--HIVDMLSKEIQELQSKPDRSAEES--------DRLRKLMLEWQFQK 1567
+ +E++ +Q++M + M ++ + Q K R EE +R +K+ E + +
Sbjct: 408 EKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMR 467
Query: 1568 RLQESKQKDEDD--EEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQ 1625
+E QK E++ E+EE + L Q+ + + + + + Q+E+ R Q++
Sbjct: 468 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE--QEEKIRDQEE 525
Query: 1626 LEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRL 1685
+ K+ +E+E + E+E RD E+K +E + E+ ++ + ++
Sbjct: 526 MWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKM 585
Query: 1686 LEPE 1689
E E
Sbjct: 586 REEE 589
Score = 60.5 bits (145), Expect = 1e-08
Identities = 56/296 (18%), Positives = 138/296 (46%), Gaps = 37/296 (12%)
Query: 1407 ERRKREEHQRWYEKEKARLEEER--------ERKRREQERKLGQMRTQSLNPAPFSPLTA 1458
E+ + +E Q W ++EK R +E++ E+K +EQE+K + +
Sbjct: 537 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREE---ERMRE 593
Query: 1459 QQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRD 1518
++ K + + R QE ++E + + Q + + + + +EE W+++
Sbjct: 594 REKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKM---------WEQE 644
Query: 1519 AKEKLEKQQQMHIVDMLSKEIQEL--QSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKD 1576
K E++++M L ++ ++L K + ++ K+ + + +K+ QE ++K
Sbjct: 645 EK-MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT 703
Query: 1577 EDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAED 1636
D E+ +++ E E++ R ++++++E + Q+Q E+M+++E E+
Sbjct: 704 WDQEKMREEE-------SMREREKKMREEE------EMMREQEEKMQEQEEKMQEQE-EE 749
Query: 1637 RARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEAPG 1692
QEE+ QEE+ ++ +++++ + +++ + + E R E + G
Sbjct: 750 MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRG 805
Score = 52.8 bits (125), Expect = 3e-06
Identities = 50/271 (18%), Positives = 119/271 (43%), Gaps = 39/271 (14%)
Query: 1398 LPSAQVAAAERRKREEHQRWYEKEKARLEEERERKR-REQERKLGQMRTQSLNPAPFSPL 1456
LP + E K +E ++ E+E+ E+E+ K+ +EQE+K + +
Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEES----M 715
Query: 1457 TAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK 1516
++ K + + R QE ++E + + Q + E + + +EE P
Sbjct: 716 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLP---- 771
Query: 1517 RDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKD 1576
+ KEKL + ++M + + ++ ++++ + ++ + +++R QE K +
Sbjct: 772 -EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRG-----------QEEKMRG 819
Query: 1577 EDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAED 1636
++++ + +++ + Q+E+ Q++ E + + E+
Sbjct: 820 QEEKMWGQE--------EKMWGQEEKMWG----------QEEKMWGQEEKMEEKMQGQEE 861
Query: 1637 RARQEEERRRQEEERTKRDAEEKRRQEEGYY 1667
+ R++EE+ R +EE+ + E+ R QEE Y
Sbjct: 862 KMREQEEKMRGQEEKMREQEEKMRGQEEKIY 892
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 75.1 bits (183), Expect = 6e-13
Identities = 60/304 (19%), Positives = 144/304 (47%), Gaps = 31/304 (10%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1466
E+ +R+E W ++EK R +EE ++ E+ R+ +M + + + +
Sbjct: 396 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 455
Query: 1467 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAK------ 1520
+R +E IRE + +Q+ R + I +E++ + W+++ K
Sbjct: 456 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKM---WRQEEKIHEQEK 512
Query: 1521 ----EKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLE-WQFQKRLQESKQK 1575
EK ++Q++M + +E +E+ + ++ E+ +++RK + W+ ++++ + ++K
Sbjct: 513 IREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEK 572
Query: 1576 DEDDEE----------EEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQ 1625
+ EE E+++ + R + E + + ++E + Q+Q
Sbjct: 573 IREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 632
Query: 1626 LEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLE-----AERRRQHDE 1680
E+MR++E ++ R++E++ R++EE+ + E + QEE + + E E+ ++ +E
Sbjct: 633 EEKMRRQE--EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 690
Query: 1681 AARR 1684
RR
Sbjct: 691 KMRR 694
Score = 70.1 bits (170), Expect = 2e-11
Identities = 64/291 (21%), Positives = 142/291 (48%), Gaps = 32/291 (10%)
Query: 1409 RKREEHQRWYEKEKARLEE--ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1466
R+ E+ Q W EK + + E+ E+E K REQE K MR Q ++M EK
Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK---MRRQ------------EEMMWEKE 409
Query: 1467 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQ 1526
++R +E + + + ++ + + I +E++ + + KR +EK+ +Q
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 469
Query: 1527 QQMHIVD-MLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDE----- 1580
++ + + ++ ++++ + ++ E+ +++ + + Q++++E +++ E +E
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 529
Query: 1581 ----EEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQ---LEEMRKRE 1633
E+E+ I ++ E R+ M Q+E+ R Q++ +E + RE
Sbjct: 530 EKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIRE 589
Query: 1634 AEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARR 1684
E++ R++EE+ R++EE T+ E+ QEE + E+ ++ +E RR
Sbjct: 590 QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE--QEEKMQEQEEKMRR 638
Score = 67.8 bits (164), Expect = 9e-11
Identities = 78/318 (24%), Positives = 145/318 (45%), Gaps = 53/318 (16%)
Query: 1407 ERRKREEHQRWYEKEKARLEEE----RERKRREQERKLGQ---MRTQSLNPAPFSPLTAQ 1459
E+ +R+E W ++EK R +EE +E K RE E K+ + +R Q + Q
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 469
Query: 1460 QMKPEKPSTLQRPQETV------IRE-----------LQPQQQPRTIERRDLQYITVSKE 1502
+ + E+ + + R +E + IRE + Q++ R E+R Q +E
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 529
Query: 1503 ELSSGDSLSPDPWKRDAK-----EKLEKQQQ--------MHIVDMLSKEIQELQSKPDRS 1549
E + W++ K EK+ KQ++ MH + ++I+E + K R
Sbjct: 530 EKIREQE---EIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQE---EKIREQEEKVWRQ 583
Query: 1550 AEESDRLRKLMLEWQFQKRLQESKQKDEDDE--EEEDDDVDTMLIMQRLEAERRARTAMP 1607
E+ + + E + + R QE ++++++ E+E+ + MQ E + R +
Sbjct: 584 EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 1608 AISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYY 1667
+ + EE+ R+Q EEM + + E QEE+ QEE+ +++ E+ RRQEE +
Sbjct: 644 REQEKKIREQEEKIREQ--EEMMQEQEEKMWEQEEKMCEQEEKMQEQE-EKMRRQEEKMW 700
Query: 1668 S-----RLEAERRRQHDE 1680
R + E+ ++H E
Sbjct: 701 EQEVRLRQQEEKMQEHQE 718
Score = 63.9 bits (154), Expect = 1e-09
Identities = 59/284 (20%), Positives = 139/284 (48%), Gaps = 34/284 (11%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEE--RERKRREQERKLGQMRTQSLNPAPFSPLTAQ 1459
++ E + E+ + ++EK + EE+ + KR+EQE K+ + + + Q
Sbjct: 439 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK---------IREQ 489
Query: 1460 QMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDA 1519
+ K + QE I E Q++ R E+R Q +EE + W++
Sbjct: 490 EEKIREQEEKMWRQEEKIHE---QEKIREEEKRQEQEEMWRQEEKIREQE---EIWRQ-- 541
Query: 1520 KEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLE-WQFQKRLQESKQKDED 1578
KEK+ +Q+ + + K+ +++ + ++ ++ +++R+ + W+ +++++E ++K +
Sbjct: 542 KEKIHEQE-----EKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIRE 596
Query: 1579 DEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRK-----RE 1633
EE+ + + M + + E+ + +Q++E + ++Q E++R+ RE
Sbjct: 597 QEEKIREQEE----MTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIRE 652
Query: 1634 AEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQ 1677
E++ R++EE +++EE+ E+ QEE + E RR++
Sbjct: 653 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 696
Score = 62.0 bits (149), Expect = 5e-09
Identities = 57/287 (19%), Positives = 139/287 (48%), Gaps = 16/287 (5%)
Query: 1398 LPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLT 1457
LP Q+ A +E Q K +A++EE R Q+++ R + +
Sbjct: 319 LPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ 378
Query: 1458 AQQMK-PEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK 1516
Q+ K E+ ++ +E + R+ + + RR + + +E++ + + W+
Sbjct: 379 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM---WE 435
Query: 1517 RDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKD 1576
++ K + E +++MH + + +E +E + + ++ E+ R + W+ +++++E ++K
Sbjct: 436 KEEKIR-ELEEKMHEQEKI-REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 493
Query: 1577 EDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQ---LEEMRKRE 1633
+ EE+ + + +++ E + + ++ + EE+ R+Q+ ++ + E
Sbjct: 494 REQEEKMWRQEEKIHEQEKIREEEKRQEQE------EMWRQEEKIREQEEIWRQKEKIHE 547
Query: 1634 AEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDE 1680
E++ R++EE+ ++EE+ D EEK R++E R E + R Q ++
Sbjct: 548 QEEKIRKQEEKMWRQEEK-MHDQEEKIREQEEKVWRQEEKIREQEEK 593
Score = 59.7 bits (143), Expect = 3e-08
Identities = 60/248 (24%), Positives = 120/248 (48%), Gaps = 49/248 (19%)
Query: 1467 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK---------- 1516
+T ++ + I EL ++ ++E L T++ EEL ++ + +
Sbjct: 246 ATQKKKADRYIEELTKERDALSLE---LYRNTITDEELKEKNAKLQEKLQLVESEKSEIQ 302
Query: 1517 ---RDAKEKLEK------QQQMHI-VDMLSKEIQELQSKPDRSAEESDRLRKLMLE---- 1562
++ K KLE+ QQQ+ D L KE+Q + +K EE++ +L +
Sbjct: 303 LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK 362
Query: 1563 -WQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERR 1621
W+ ++++QE ++K ++ EE+ + + I ++ E RR M ++E+ R
Sbjct: 363 MWRQEEKIQEWEEKIQEQEEKIREQEEK--IREQEEKMRRQEEMMWE-------KEEKMR 413
Query: 1622 RQQQL---EEMRKREAEDRARQEEERRRQEEERTK-----RDAEEKRRQEEGYYSRLEAE 1673
RQ+++ +E + R E+ ++EE+ R+ EE+ R+ EEKR++EE ++ +
Sbjct: 414 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE----KIREQ 469
Query: 1674 RRRQHDEA 1681
+RQ EA
Sbjct: 470 EKRQEQEA 477
Score = 57.0 bits (136), Expect = 2e-07
Identities = 58/280 (20%), Positives = 133/280 (47%), Gaps = 29/280 (10%)
Query: 1410 KREEHQRWYEKEKARLE-EERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPST 1468
K +E + E EK+ ++ +E KR+ + KL L QQ +
Sbjct: 286 KLQEKLQLVESEKSEIQLNVKELKRKLERAKL---------------LLPQQQLQAEADH 330
Query: 1469 LQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQ 1528
L + ++V +LQ Q + + R + +EE W+ +E+ EK ++
Sbjct: 331 LGKELQSVSAKLQAQVEENELWNR----LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 386
Query: 1529 MHIVDMLSKEIQELQSKPDRSAEESDRLRKLM-LEWQFQKRLQESKQKDEDDEEEEDDDV 1587
+ + ++ ++++ + + E+ +++R+ + W+ +++++ ++ + EE+ +
Sbjct: 387 QE--EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 444
Query: 1588 DTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQ 1647
+ M +++ + R I + Q++E + +Q E++R++E + R QEE+ RQ
Sbjct: 445 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR-EQEEKMWRQ 503
Query: 1648 EE---ERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARR 1684
EE E+ K EEKR+++E + + E+ R+ +E R+
Sbjct: 504 EEKIHEQEKIREEEKRQEQEEMWR--QEEKIREQEEIWRQ 541
Score = 52.0 bits (123), Expect = 5e-06
Identities = 56/270 (20%), Positives = 119/270 (44%), Gaps = 19/270 (7%)
Query: 1419 EKEKARLEEERERKRREQERKLGQMR------TQSLNPAPFSPLTAQQMKPEKPSTLQRP 1472
E E+ + +E RRE E ++ +R T+ +S +Q++ E + R
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 228
Query: 1473 QETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR-----DAKEKLEKQQ 1527
++ + +Q + + + +E D+LS + ++ + KEK K Q
Sbjct: 229 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 288
Query: 1528 QMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDV 1587
+ + ++ E E+Q + +R + L+ + Q Q ++ + + V
Sbjct: 289 EK--LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 346
Query: 1588 DTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQ 1647
+ + RL ++ + + +Q+ E + Q+Q E++R E E++ R++EE+ R+
Sbjct: 347 EENELWNRLNQQQEEKMWRQE----EKIQEWEEKIQEQEEKIR--EQEEKIREQEEKMRR 400
Query: 1648 EEERTKRDAEEKRRQEEGYYSRLEAERRRQ 1677
+EE E+ RRQEE + + E RR++
Sbjct: 401 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 430
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
Length = 1293
Score = 73.6 bits (179), Expect = 2e-12
Identities = 81/338 (23%), Positives = 143/338 (42%), Gaps = 50/338 (14%)
Query: 1348 IPATPVAVSQPIRT---DLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVA 1404
IP+ +VS P +L P P V G + +D P P L A+ A
Sbjct: 670 IPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAA 729
Query: 1405 AAER---------------RKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLN 1449
E+ RKR+E R ++E R ++E ERKRRE+E + + ++L
Sbjct: 730 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEAL- 788
Query: 1450 PAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDS 1509
+ + E+ L+R +E R+ Q + R ERR + +EEL
Sbjct: 789 ----------RRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 838
Query: 1510 LSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRL 1569
W R+ +E + ++ + + +E L+ EE +R RK LE Q QK L
Sbjct: 839 EEAAKWAREEEEAQRRLEENRL--RMEEEAARLRH------EEEERKRK-ELEVQRQKEL 889
Query: 1570 QESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQ---QL 1626
+Q+ ++ + Q+ + ++ A+ +P+ S + + Q L
Sbjct: 890 MRQRQQQQEALRR---------LQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSL 940
Query: 1627 EEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEE 1664
E++K E E + EE+RRQ+ E K +++++Q++
Sbjct: 941 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 978
Score = 65.9 bits (159), Expect = 4e-10
Identities = 73/285 (25%), Positives = 129/285 (45%), Gaps = 47/285 (16%)
Query: 1415 QRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQE 1474
Q+ Y + A+ ++ +++Q+ L + Q+L ++ Q + P ++ P
Sbjct: 627 QQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMR----ISDQNIIPSVTRSVSVPDT 682
Query: 1475 TVIRELQPQ-QQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVD 1533
I ELQP QP E + + + D+ +P P A E+L++ ++
Sbjct: 683 GSIWELQPTASQPTVWEGGSVWDLPL--------DTTTPGP----ALEQLQQLEKAKAAK 730
Query: 1534 MLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIM 1593
L +E +E + + R EE R +L +R QE + + +EE + + + +
Sbjct: 731 -LEQERREAEMRAKREEEERKRQEEL-------RRQQEEILRRQQEEERKRREEEELARR 782
Query: 1594 QRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTK 1653
++ EA RR R ++E ++Q EE +++ E+ R+ EERRR+EEER K
Sbjct: 783 KQEEALRRQR-------------EQEIALRRQREEEERQQQEEALRRLEERRREEEERRK 829
Query: 1654 R---------DAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
+ +A + R+EE RLE R R +EAAR E E
Sbjct: 830 QEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 874
Score = 52.4 bits (124), Expect = 4e-06
Identities = 47/170 (27%), Positives = 76/170 (44%), Gaps = 7/170 (4%)
Query: 1526 QQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDD 1585
Q Q ++ ++ Q K S+++ +L L+ ++Q K ++ S Q
Sbjct: 620 QYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK-MRISDQNIIPSVTRSVS 678
Query: 1586 DVDTMLIMQRLEAERRARTAMPAISVLDLLQDEER-----RRQQQLEEMRKREAEDRARQ 1640
DT I + L+ T SV DL D + QQLE+ + + E R+
Sbjct: 679 VPDTGSIWE-LQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERRE 737
Query: 1641 EEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEA 1690
E R ++EEE KR E +R+QEE + E ER+R+ +E R + EA
Sbjct: 738 AEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEA 787
Score = 37.4 bits (85), Expect = 0.14
Identities = 26/131 (19%), Positives = 64/131 (48%), Gaps = 1/131 (0%)
Query: 128 LKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEAL-RQASDKDDRP 186
L+ E +A+ E++ +E + + + L +++++E+K+RE+E L R+ ++ R
Sbjct: 731 LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 790
Query: 187 FQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSDGRPDSG 246
+ +++ R E + E + R +RR+Q++L ++ +E + R +
Sbjct: 791 QREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEE 850
Query: 247 GTLRIYADSLK 257
R+ + L+
Sbjct: 851 AQRRLEENRLR 861
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 73.6 bits (179), Expect = 2e-12
Identities = 81/338 (23%), Positives = 143/338 (42%), Gaps = 50/338 (14%)
Query: 1348 IPATPVAVSQPIRT---DLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVA 1404
IP+ +VS P +L P P V G + +D P P L A+ A
Sbjct: 697 IPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAA 756
Query: 1405 AAER---------------RKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLN 1449
E+ RKR+E R ++E R ++E ERKRRE+E + + ++L
Sbjct: 757 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEAL- 815
Query: 1450 PAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDS 1509
+ + E+ L+R +E R+ Q + R ERR + +EEL
Sbjct: 816 ----------RRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 865
Query: 1510 LSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRL 1569
W R+ +E + ++ + + +E L+ EE +R RK LE Q QK L
Sbjct: 866 EEAAKWAREEEEAQRRLEENRL--RMEEEAARLRH------EEEERKRK-ELEVQRQKEL 916
Query: 1570 QESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQ---QL 1626
+Q+ ++ + Q+ + ++ A+ +P+ S + + Q L
Sbjct: 917 MRQRQQQQEALRR---------LQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSL 967
Query: 1627 EEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEE 1664
E++K E E + EE+RRQ+ E K +++++Q++
Sbjct: 968 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 1005
Score = 65.9 bits (159), Expect = 4e-10
Identities = 73/285 (25%), Positives = 129/285 (45%), Gaps = 47/285 (16%)
Query: 1415 QRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQE 1474
Q+ Y + A+ ++ +++Q+ L + Q+L ++ Q + P ++ P
Sbjct: 654 QQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMR----ISDQNIIPSVTRSVSVPDT 709
Query: 1475 TVIRELQPQ-QQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVD 1533
I ELQP QP E + + + D+ +P P A E+L++ ++
Sbjct: 710 GSIWELQPTASQPTVWEGGSVWDLPL--------DTTTPGP----ALEQLQQLEKAKAAK 757
Query: 1534 MLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIM 1593
L +E +E + + R EE R +L +R QE + + +EE + + + +
Sbjct: 758 -LEQERREAEMRAKREEEERKRQEEL-------RRQQEEILRRQQEEERKRREEEELARR 809
Query: 1594 QRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTK 1653
++ EA RR R ++E ++Q EE +++ E+ R+ EERRR+EEER K
Sbjct: 810 KQEEALRRQR-------------EQEIALRRQREEEERQQQEEALRRLEERRREEEERRK 856
Query: 1654 R---------DAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
+ +A + R+EE RLE R R +EAAR E E
Sbjct: 857 QEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 901
Score = 52.4 bits (124), Expect = 4e-06
Identities = 47/170 (27%), Positives = 76/170 (44%), Gaps = 7/170 (4%)
Query: 1526 QQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDD 1585
Q Q ++ ++ Q K S+++ +L L+ ++Q K ++ S Q
Sbjct: 647 QYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK-MRISDQNIIPSVTRSVS 705
Query: 1586 DVDTMLIMQRLEAERRARTAMPAISVLDLLQDEER-----RRQQQLEEMRKREAEDRARQ 1640
DT I + L+ T SV DL D + QQLE+ + + E R+
Sbjct: 706 VPDTGSIWE-LQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERRE 764
Query: 1641 EEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEA 1690
E R ++EEE KR E +R+QEE + E ER+R+ +E R + EA
Sbjct: 765 AEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEA 814
Score = 37.4 bits (85), Expect = 0.14
Identities = 26/131 (19%), Positives = 64/131 (48%), Gaps = 1/131 (0%)
Query: 128 LKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEAL-RQASDKDDRP 186
L+ E +A+ E++ +E + + + L +++++E+K+RE+E L R+ ++ R
Sbjct: 758 LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 817
Query: 187 FQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSDGRPDSG 246
+ +++ R E + E + R +RR+Q++L ++ +E + R +
Sbjct: 818 QREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEE 877
Query: 247 GTLRIYADSLK 257
R+ + L+
Sbjct: 878 AQRRLEENRLR 888
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 73.6 bits (179), Expect = 2e-12
Identities = 81/338 (23%), Positives = 143/338 (42%), Gaps = 50/338 (14%)
Query: 1348 IPATPVAVSQPIRT---DLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVA 1404
IP+ +VS P +L P P V G + +D P P L A+ A
Sbjct: 676 IPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAA 735
Query: 1405 AAER---------------RKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLN 1449
E+ RKR+E R ++E R ++E ERKRRE+E + + ++L
Sbjct: 736 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEAL- 794
Query: 1450 PAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDS 1509
+ + E+ L+R +E R+ Q + R ERR + +EEL
Sbjct: 795 ----------RRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 844
Query: 1510 LSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRL 1569
W R+ +E + ++ + + +E L+ EE +R RK LE Q QK L
Sbjct: 845 EEAAKWAREEEEAQRRLEENRL--RMEEEAARLRH------EEEERKRK-ELEVQRQKEL 895
Query: 1570 QESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQ---QL 1626
+Q+ ++ + Q+ + ++ A+ +P+ S + + Q L
Sbjct: 896 MRQRQQQQEALRR---------LQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSL 946
Query: 1627 EEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEE 1664
E++K E E + EE+RRQ+ E K +++++Q++
Sbjct: 947 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 984
Score = 65.9 bits (159), Expect = 4e-10
Identities = 73/285 (25%), Positives = 129/285 (45%), Gaps = 47/285 (16%)
Query: 1415 QRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQE 1474
Q+ Y + A+ ++ +++Q+ L + Q+L ++ Q + P ++ P
Sbjct: 633 QQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMR----ISDQNIIPSVTRSVSVPDT 688
Query: 1475 TVIRELQPQ-QQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVD 1533
I ELQP QP E + + + D+ +P P A E+L++ ++
Sbjct: 689 GSIWELQPTASQPTVWEGGSVWDLPL--------DTTTPGP----ALEQLQQLEKAKAAK 736
Query: 1534 MLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIM 1593
L +E +E + + R EE R +L +R QE + + +EE + + + +
Sbjct: 737 -LEQERREAEMRAKREEEERKRQEEL-------RRQQEEILRRQQEEERKRREEEELARR 788
Query: 1594 QRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTK 1653
++ EA RR R ++E ++Q EE +++ E+ R+ EERRR+EEER K
Sbjct: 789 KQEEALRRQR-------------EQEIALRRQREEEERQQQEEALRRLEERRREEEERRK 835
Query: 1654 R---------DAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
+ +A + R+EE RLE R R +EAAR E E
Sbjct: 836 QEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
Score = 52.4 bits (124), Expect = 4e-06
Identities = 47/170 (27%), Positives = 76/170 (44%), Gaps = 7/170 (4%)
Query: 1526 QQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDD 1585
Q Q ++ ++ Q K S+++ +L L+ ++Q K ++ S Q
Sbjct: 626 QYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK-MRISDQNIIPSVTRSVS 684
Query: 1586 DVDTMLIMQRLEAERRARTAMPAISVLDLLQDEER-----RRQQQLEEMRKREAEDRARQ 1640
DT I + L+ T SV DL D + QQLE+ + + E R+
Sbjct: 685 VPDTGSIWE-LQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERRE 743
Query: 1641 EEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEA 1690
E R ++EEE KR E +R+QEE + E ER+R+ +E R + EA
Sbjct: 744 AEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEA 793
Score = 37.4 bits (85), Expect = 0.14
Identities = 26/131 (19%), Positives = 64/131 (48%), Gaps = 1/131 (0%)
Query: 128 LKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEAL-RQASDKDDRP 186
L+ E +A+ E++ +E + + + L +++++E+K+RE+E L R+ ++ R
Sbjct: 737 LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 796
Query: 187 FQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSDGRPDSG 246
+ +++ R E + E + R +RR+Q++L ++ +E + R +
Sbjct: 797 QREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEE 856
Query: 247 GTLRIYADSLK 257
R+ + L+
Sbjct: 857 AQRRLEENRLR 867
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 73.6 bits (179), Expect = 2e-12
Identities = 81/338 (23%), Positives = 143/338 (42%), Gaps = 50/338 (14%)
Query: 1348 IPATPVAVSQPIRT---DLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVA 1404
IP+ +VS P +L P P V G + +D P P L A+ A
Sbjct: 676 IPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAA 735
Query: 1405 AAER---------------RKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLN 1449
E+ RKR+E R ++E R ++E ERKRRE+E + + ++L
Sbjct: 736 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEAL- 794
Query: 1450 PAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDS 1509
+ + E+ L+R +E R+ Q + R ERR + +EEL
Sbjct: 795 ----------RRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 844
Query: 1510 LSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRL 1569
W R+ +E + ++ + + +E L+ EE +R RK LE Q QK L
Sbjct: 845 EEAAKWAREEEEAQRRLEENRL--RMEEEAARLRH------EEEERKRK-ELEVQRQKEL 895
Query: 1570 QESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQ---QL 1626
+Q+ ++ + Q+ + ++ A+ +P+ S + + Q L
Sbjct: 896 MRQRQQQQEALRR---------LQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSL 946
Query: 1627 EEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEE 1664
E++K E E + EE+RRQ+ E K +++++Q++
Sbjct: 947 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 984
Score = 65.9 bits (159), Expect = 4e-10
Identities = 73/285 (25%), Positives = 129/285 (45%), Gaps = 47/285 (16%)
Query: 1415 QRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQE 1474
Q+ Y + A+ ++ +++Q+ L + Q+L ++ Q + P ++ P
Sbjct: 633 QQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMR----ISDQNIIPSVTRSVSVPDT 688
Query: 1475 TVIRELQPQ-QQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVD 1533
I ELQP QP E + + + D+ +P P A E+L++ ++
Sbjct: 689 GSIWELQPTASQPTVWEGGSVWDLPL--------DTTTPGP----ALEQLQQLEKAKAAK 736
Query: 1534 MLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIM 1593
L +E +E + + R EE R +L +R QE + + +EE + + + +
Sbjct: 737 -LEQERREAEMRAKREEEERKRQEEL-------RRQQEEILRRQQEEERKRREEEELARR 788
Query: 1594 QRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTK 1653
++ EA RR R ++E ++Q EE +++ E+ R+ EERRR+EEER K
Sbjct: 789 KQEEALRRQR-------------EQEIALRRQREEEERQQQEEALRRLEERRREEEERRK 835
Query: 1654 R---------DAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
+ +A + R+EE RLE R R +EAAR E E
Sbjct: 836 QEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
Score = 52.4 bits (124), Expect = 4e-06
Identities = 47/170 (27%), Positives = 76/170 (44%), Gaps = 7/170 (4%)
Query: 1526 QQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDD 1585
Q Q ++ ++ Q K S+++ +L L+ ++Q K ++ S Q
Sbjct: 626 QYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK-MRISDQNIIPSVTRSVS 684
Query: 1586 DVDTMLIMQRLEAERRARTAMPAISVLDLLQDEER-----RRQQQLEEMRKREAEDRARQ 1640
DT I + L+ T SV DL D + QQLE+ + + E R+
Sbjct: 685 VPDTGSIWE-LQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERRE 743
Query: 1641 EEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEA 1690
E R ++EEE KR E +R+QEE + E ER+R+ +E R + EA
Sbjct: 744 AEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEA 793
Score = 37.4 bits (85), Expect = 0.14
Identities = 26/131 (19%), Positives = 64/131 (48%), Gaps = 1/131 (0%)
Query: 128 LKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEAL-RQASDKDDRP 186
L+ E +A+ E++ +E + + + L +++++E+K+RE+E L R+ ++ R
Sbjct: 737 LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 796
Query: 187 FQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSDGRPDSG 246
+ +++ R E + E + R +RR+Q++L ++ +E + R +
Sbjct: 797 QREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEE 856
Query: 247 GTLRIYADSLK 257
R+ + L+
Sbjct: 857 AQRRLEENRLR 867
>gi|148746189 multiple PDZ domain protein [Homo sapiens]
Length = 2041
Score = 72.0 bits (175), Expect = 5e-12
Identities = 44/121 (36%), Positives = 67/121 (55%), Gaps = 9/121 (7%)
Query: 969 HTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKK-QNGMGLSIVAAKGA 1027
H + P + ++ F G S + Q P+ ++TL++ +G+G SIV G+
Sbjct: 1927 HQQEPASSSLSFTGLTSSS--------IFQDDLGPPQCKSITLERGPDGLGFSIVGGYGS 1978
Query: 1028 GQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLE 1087
L IYVK+V GAA DGRL GDQ+++V+G+SL G++ E A ++ RT VTL
Sbjct: 1979 PHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLM 2038
Query: 1088 V 1088
V
Sbjct: 2039 V 2039
Score = 64.7 bits (156), Expect = 8e-10
Identities = 37/94 (39%), Positives = 54/94 (57%), Gaps = 4/94 (4%)
Query: 1002 KEPEIITVTLKKQNGMGLSIVAAKGAGQDKL---GIYVKSVVKGGAADVDGRLAAGDQLL 1058
+E E V L K N GL I A G KL GI+VKS+ K A + DGR+ GDQ++
Sbjct: 371 EESETFDVELTK-NVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDGRIQIGDQII 429
Query: 1059 SVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQG 1092
+VDG +L G + ++A E++ T V L + ++G
Sbjct: 430 AVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRG 463
Score = 59.3 bits (142), Expect = 3e-08
Identities = 34/81 (41%), Positives = 50/81 (61%), Gaps = 9/81 (11%)
Query: 1002 KEPEI---ITVTLKKQ--NGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQ 1056
KE E+ +T+ L+K+ G+GLSIV + + G++V +VKGG AD DGRL GDQ
Sbjct: 1716 KEEEVCDTLTIELQKKPGKGLGLSIVGKR----NDTGVFVSDIVKGGIADADGRLMQGDQ 1771
Query: 1057 LLSVDGRSLVGLSQERAAELM 1077
+L V+G + +QE A L+
Sbjct: 1772 ILMVNGEDVRNATQEAVAALL 1792
Score = 54.3 bits (129), Expect = 1e-06
Identities = 28/80 (35%), Positives = 47/80 (58%), Gaps = 6/80 (7%)
Query: 1015 NGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAA 1074
+G+G I+ K G + VK+++ GG AD GRL +GD +L + L G+S E+ A
Sbjct: 265 SGLGFGIIGGKATG-----VIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVA 319
Query: 1075 ELMTRTSSVVTLEVAKQGAI 1094
+++ + + V L +A+ GAI
Sbjct: 320 QVLRQCGNRVKLMIAR-GAI 338
Score = 52.0 bits (123), Expect = 5e-06
Identities = 50/188 (26%), Positives = 81/188 (43%), Gaps = 35/188 (18%)
Query: 981 EGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAG------QDKLGI 1034
EG ES L +NT + +P + + + +G+SIV +G G + GI
Sbjct: 1130 EGEGEESEL--QNTAYSN--WNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGI 1185
Query: 1035 YVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAI 1094
++K V++ A +G L GD+++ VDG L S E+A E + + + V V
Sbjct: 1186 FIKHVLEDSPAGKNGTLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMV------ 1239
Query: 1095 YHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSPESPQL-----PWAE 1149
+++N+P R S P + YN S+ N +S Q+ P
Sbjct: 1240 ----QSIINRP----------RKSPLPSLLHNLYPKYNFSSTNPFADSLQINADKAPSQS 1285
Query: 1150 YSEPKKLP 1157
SEP+K P
Sbjct: 1286 ESEPEKAP 1293
Score = 51.6 bits (122), Expect = 7e-06
Identities = 24/87 (27%), Positives = 50/87 (57%), Gaps = 1/87 (1%)
Query: 1005 EIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRS 1064
E+ + G+G S+V + + +LGI+V+ + +G A DGRL DQ+L+++G++
Sbjct: 136 EVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDGRLKETDQILAINGQA 195
Query: 1065 L-VGLSQERAAELMTRTSSVVTLEVAK 1090
L ++ ++A ++ + V L +A+
Sbjct: 196 LDQTITHQQAISILQKAKDTVQLVIAR 222
Score = 51.6 bits (122), Expect = 7e-06
Identities = 35/108 (32%), Positives = 61/108 (56%), Gaps = 9/108 (8%)
Query: 981 EGADY--ESHLLRENTE--LAQPLRKEPEIITVTLKKQNG-MGLSIVAAKGAGQDKLGIY 1035
+G++Y E L N E + Q + KE T+ + K N +G+++ A K D LG+
Sbjct: 977 KGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGMTVSANK----DGLGMI 1032
Query: 1036 VKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSV 1083
V+S++ GGA DGR+A GD +LS++ S + ++ +A ++ R S +
Sbjct: 1033 VRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI 1080
Score = 49.7 bits (117), Expect = 3e-05
Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 22/131 (16%)
Query: 1012 KKQNGMGLSIVAAKGAGQDKL-GIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQ 1070
K Q G+G++I + +D L G+ +KS+ + G A DGRL GDQ+L+VD +VG
Sbjct: 1488 KDQGGLGIAI-----SEEDTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPI 1542
Query: 1071 ERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFEL 1130
E+ L+ V L + + +P Q + G+ K+ L
Sbjct: 1543 EKFISLLKTAKMTVKLTI--------------HAENPDSQAVPSAAGAASGEKKNSSQSL 1588
Query: 1131 YNNSTQNGSPE 1141
Q+GSPE
Sbjct: 1589 M--VPQSGSPE 1597
Score = 47.4 bits (111), Expect = 1e-04
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 6/86 (6%)
Query: 1012 KKQNGMGLSIVAAKGAGQDKL--GIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLS 1069
K + G+GLSIV G D L I + V + GAA DGRL AGDQ+L V+G L +
Sbjct: 1634 KGRTGLGLSIVG----GSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKAT 1689
Query: 1070 QERAAELMTRTSSVVTLEVAKQGAIY 1095
+ A ++ +T V L + + A Y
Sbjct: 1690 HDEAINVLRQTPQRVRLTLYRDEAPY 1715
Score = 45.4 bits (106), Expect = 5e-04
Identities = 23/75 (30%), Positives = 42/75 (56%), Gaps = 2/75 (2%)
Query: 1012 KKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQE 1071
K +G+GLS+ K + ++ +++ + GAA DGRL D+LL ++G+ L G S +
Sbjct: 1355 KGHSGLGLSLAGNKD--RSRMSVFIVGIDPNGAAGKDGRLQIADELLEINGQILYGRSHQ 1412
Query: 1072 RAAELMTRTSSVVTL 1086
A+ ++ S V +
Sbjct: 1413 NASSIIKCAPSKVKI 1427
Score = 40.8 bits (94), Expect = 0.012
Identities = 32/85 (37%), Positives = 44/85 (51%), Gaps = 10/85 (11%)
Query: 1012 KKQNGMGLSIVAAKGAGQDKLG-----IYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLV 1066
K G+G SI+ QD + I ++S+V GG A+ DGRL GD+L+ V+ +L
Sbjct: 705 KGSKGLGFSILDY----QDPIDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLE 760
Query: 1067 GLSQERAAE-LMTRTSSVVTLEVAK 1090
S E A E L S V + VAK
Sbjct: 761 NSSLEEAVEALKGAPSGTVRIGVAK 785
Score = 39.7 bits (91), Expect = 0.027
Identities = 22/89 (24%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
Query: 1008 TVTLKK--QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSL 1065
TV +KK + +G+SI G+ + I++ + G A +L GD+++++ G S
Sbjct: 1833 TVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTST 1892
Query: 1066 VGLSQERAAELMTRTSSVVTLEVAKQGAI 1094
G++ +A L+ S + ++V G +
Sbjct: 1893 EGMTHTQAVNLLKNASGSIEMQVVAGGDV 1921
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/85 (27%), Positives = 44/85 (51%), Gaps = 9/85 (10%)
Query: 1005 EIITVTLKK---QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVD 1061
EI+ + K +G+G+S+ A G +++SV+ G G+L +GD+LL V+
Sbjct: 550 EIVVAHVSKFSENSGLGISLEATVGHH------FIRSVLPEGPVGHSGKLFSGDELLEVN 603
Query: 1062 GRSLVGLSQERAAELMTRTSSVVTL 1086
G +L+G + + ++ VT+
Sbjct: 604 GITLLGENHQDVVNILKELPIEVTM 628
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
Length = 570
Score = 71.6 bits (174), Expect = 6e-12
Identities = 61/278 (21%), Positives = 132/278 (47%), Gaps = 50/278 (17%)
Query: 1407 ERRKREEHQRWYEKEKARLEEE----RERKRREQERKLGQMRTQSLNPAPFSPLTAQQMK 1462
E+ +R+E W ++EK R +EE +E K RE E K+ + + Q+ K
Sbjct: 316 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK----------IREQEEK 365
Query: 1463 PEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEK 1522
R +E IRE + +Q+ R + I +E++ + + ++ +EK
Sbjct: 366 --------RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMM-----QEQEEK 412
Query: 1523 LEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEE 1582
+ +Q++ + ++ +E+Q + ++ + +++R+ +K+++E ++K + EE
Sbjct: 413 MGEQEEK-----MWEQEEEMQEQEEKMRRQEEKIREQ------EKKIREQEEKIREQEEM 461
Query: 1583 EDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQL---EEMRKREAEDRAR 1639
+ + M + E+ A+ Q+E+ RRQ++ +E + RE E++ R
Sbjct: 462 MQEQEEKMGEQEGKMCEQEAKMQE---------QEEKMRRQEEKIREQEKKIREQEEKIR 512
Query: 1640 QEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQ 1677
++EE +++EE+ E+ QEE + E RR++
Sbjct: 513 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 550
Score = 70.1 bits (170), Expect = 2e-11
Identities = 56/289 (19%), Positives = 142/289 (49%), Gaps = 38/289 (13%)
Query: 1410 KREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTL 1469
+++E + W ++EK +ERE K +EQE K+ + + ++M EK +
Sbjct: 284 QQQEEKMWRQEEKI---QEREEKIQEQEEKIREQEEKMRRQ--------EEMMWEKEEKM 332
Query: 1470 QRPQETV------IRELQPQ--QQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
+R +E + IREL+ + +Q + E+ + + E W+++ K
Sbjct: 333 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 392
Query: 1522 KLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQK-RLQESKQKDEDDE 1580
+ ++++ +M+ ++ +++ + ++ E+ + +++ + + Q+ +++E ++K + E
Sbjct: 393 REQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQE 452
Query: 1581 EEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQ 1640
E+ + + M + E+ + ++E + Q+Q E+MR++ E++ R+
Sbjct: 453 EKIREQEEMMQEQEEKMGEQEGKMC-----------EQEAKMQEQEEKMRRQ--EEKIRE 499
Query: 1641 EEERRRQEEERTKRDAEEKRRQEEGYYSRLE-----AERRRQHDEAARR 1684
+E++ R++EE+ + E + QEE + + E E+ ++ +E RR
Sbjct: 500 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 548
Score = 65.5 bits (158), Expect = 5e-10
Identities = 63/297 (21%), Positives = 137/297 (46%), Gaps = 63/297 (21%)
Query: 1393 ANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAP 1452
A+ +G V+A + + EE++ W RL +++E K QE K+ + +
Sbjct: 255 ADHLGKELQSVSAKLQAQVEENELWN-----RLNQQQEEKMWRQEEKIQEREEK------ 303
Query: 1453 FSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSP 1512
+ Q+ K + R QE ++ E + + RR + + +E++
Sbjct: 304 ---IQEQEEKIREQEEKMRRQEEMMWEKEEKM------RRQEEMMWEKEEKI-------- 346
Query: 1513 DPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQES 1572
R+ +EK+ +Q+++ +E +E + + ++ E+ R + W+ +++++E
Sbjct: 347 ----RELEEKMHEQEKI-------REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 395
Query: 1573 KQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRK- 1631
++K + EE +MQ E + + + + ++E Q+Q E+MR+
Sbjct: 396 EEKIREQEE----------MMQEQEEKMGEQE--------EKMWEQEEEMQEQEEKMRRQ 437
Query: 1632 ----REAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARR 1684
RE E + R++EE+ R++EE + + EEK ++EG EA+ + Q ++ R+
Sbjct: 438 EEKIREQEKKIREQEEKIREQEEMMQ-EQEEKMGEQEGKMCEQEAKMQEQEEKMRRQ 493
Score = 60.1 bits (144), Expect = 2e-08
Identities = 58/286 (20%), Positives = 141/286 (49%), Gaps = 22/286 (7%)
Query: 1410 KREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTL 1469
K +E + E EK+ ++ + +R+ ER + Q L + ++++
Sbjct: 213 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAE--ADHLGKELQSVSAKLQ 270
Query: 1470 QRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQM 1529
+ +E + QQQ + R++ + I +E++ + R+ +EK+ +Q++M
Sbjct: 271 AQVEENELWNRLNQQQEEKMWRQE-EKIQEREEKIQEQEEKI-----REQEEKMRRQEEM 324
Query: 1530 HIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDT 1589
M KE ++++ + + E+ +++R+L + Q++++E ++K +++E+ + +
Sbjct: 325 ----MWEKE-EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 379
Query: 1590 MLIMQRLEAERRARTAMPAISVLD-LLQDEERRRQQQLEEMRKREAEDRARQEEERRRQ- 1647
+ E + R I + ++Q++E + +Q E+M ++E E + ++E+ RR++
Sbjct: 380 EQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEE 439
Query: 1648 ---EEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEA 1690
E+E+ R+ EEK R++E + E+ + E ++ E EA
Sbjct: 440 KIREQEKKIREQEEKIREQE----EMMQEQEEKMGEQEGKMCEQEA 481
Score = 49.3 bits (116), Expect = 3e-05
Identities = 59/233 (25%), Positives = 114/233 (48%), Gaps = 30/233 (12%)
Query: 1473 QETVIRELQPQQQP---RTIERRDLQYI------TVSKEELSSGDSLSP--DPWK--RDA 1519
QE + REL+ Q Q T ++ +LQ V + E + D +S D WK +
Sbjct: 106 QEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGEL 165
Query: 1520 KEKL-----EKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESK- 1573
++ L +K++ ++ L+KE L + R+ + L++ + Q + +L ES+
Sbjct: 166 EQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEK 225
Query: 1574 ---QKDEDDEEEEDDDVDTMLIMQRLEAER-RARTAMPAISVLDLLQDEE-----RRRQQ 1624
Q + + + + + +L Q+L+AE + ++S Q EE R QQ
Sbjct: 226 SEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQ 285
Query: 1625 QLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQ 1677
Q E+M ++E ++ ++ EE+ +++EE+ + E+ RRQEE + + E RR++
Sbjct: 286 QEEKMWRQE--EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 336
Score = 42.4 bits (98), Expect = 0.004
Identities = 56/284 (19%), Positives = 122/284 (42%), Gaps = 25/284 (8%)
Query: 1419 EKEKARLEEERERKRREQERKLGQMR------TQSLNPAPFSPLTAQQMKPEKPSTLQRP 1472
E E+ + +E RRE E ++ +R T+ +S +Q++ E + R
Sbjct: 96 EDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 155
Query: 1473 QETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR-----DAKEKLEKQQ 1527
++ + +Q + + + +E D+LS + ++ + KEK K Q
Sbjct: 156 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 215
Query: 1528 QMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDV 1587
+ + ++ E E+Q + +R + L+ + Q Q ++ + + V
Sbjct: 216 EK--LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 273
Query: 1588 DTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQE----EE 1643
+ + RL ++ + + +Q+ E + Q+Q E++R++E + R ++E +E
Sbjct: 274 EENELWNRLNQQQEEKMWRQE----EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKE 329
Query: 1644 RRRQEEERTKRDAEEKRRQ-EEGYYSR---LEAERRRQHDEAAR 1683
+ + +E + EEK R+ EE + + E E +RQ +E R
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 373
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 71.2 bits (173), Expect = 8e-12
Identities = 74/323 (22%), Positives = 131/323 (40%), Gaps = 70/323 (21%)
Query: 1377 DFDGMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRW-----------YEKEKARL 1425
+FD D L P Q + E + +R+ Y+K R
Sbjct: 120 EFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRD 179
Query: 1426 EEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQ 1485
EE +++ +E+E + ++ KP++ S + E ++ E + Q
Sbjct: 180 AEENKKEDKEKEEE-------------------EEEKPKRGSIGENQVEVMVEEKTTESQ 220
Query: 1486 PRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSK 1545
T+ L +G S +P + + +E+ + H E +
Sbjct: 221 EETVVM-----------SLKNGQISSEEPKQEEEREQGSDEISHH----------EKMEE 259
Query: 1546 PDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEE--EDDDVDTMLIMQRLEAERRAR 1603
D+ E++R R LE + ++R++ + K DE E ++ +R EAE R R
Sbjct: 260 EDKERAEAERAR---LEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERER 316
Query: 1604 TAMPAISVLDLLQDEERR---RQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKR 1660
+++EE+R +Q+++E KR AE+R R +EE +R EER + EEKR
Sbjct: 317 -----------MREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKR 365
Query: 1661 RQEEGYYSRLEAERRRQHDEAAR 1683
EE +R E E + + +E R
Sbjct: 366 AAEERQRARAEEEEKAKVEEQKR 388
Score = 63.2 bits (152), Expect = 2e-09
Identities = 64/298 (21%), Positives = 145/298 (48%), Gaps = 20/298 (6%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1466
ERR+ EE +R E+EK R EER+R + E+E++ + R + + Q++K E+
Sbjct: 307 ERREAEERERMREEEK-RAAEERQRIK-EEEKRAAEERQRIKEEEKRAAEERQRIKEEEK 364
Query: 1467 STLQ-----RPQETVIRELQPQQQPRTIERRD--LQYITVSKEELSSGDSLSPDPWKRDA 1519
+ R +E +++ Q++ + +E + +Q + E++ + W +
Sbjct: 365 RAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKV---EQKIEGKWVNEK 421
Query: 1520 KEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDED- 1578
K + +K Q + ++ ++Q+K ++ E+ +K ++ + K+ +E K++ +
Sbjct: 422 KAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSF 481
Query: 1579 -DEEEEDDDVDTM---LIMQRLEAERRARTAMPAISVLDLLQDE---ERRRQQQLEEMRK 1631
D ++ +V + + +L+ + + +D + E + ++LEE+R+
Sbjct: 482 MDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRR 541
Query: 1632 REAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
R E + + E+ +++++E E K+++EE E E+RR+ +EA R+L E E
Sbjct: 542 RRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEE 599
Score = 62.4 bits (150), Expect = 4e-09
Identities = 102/432 (23%), Positives = 173/432 (40%), Gaps = 59/432 (13%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
++ E+R EE QR E+EK R EER+R + E++R + + + + Q+
Sbjct: 330 RIKEEEKRAAEERQRIKEEEK-RAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKR 388
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
+ QET I+ + +Q+ IE + + E+ + D L K+ +E
Sbjct: 389 NKQLEEKKHAMQETKIKGEKVEQK---IEGKWVN------EKKAQEDKLQTAVLKKQGEE 439
Query: 1522 KLEKQQ------QMHIVDMLSKEIQELQSKPDRSAEES-----DRLRKLMLEWQFQKRLQ 1570
K K Q Q +EI++ + K D+ +E DR +
Sbjct: 440 KGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFM 499
Query: 1571 ESKQKDEDD-----------EEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEE 1619
K K ++ + +E + + +RLE RR R + + L+ ++
Sbjct: 500 THKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETES-EEFEKLKQKQ 558
Query: 1620 RRRQQQLEEMRKREAEDR-ARQEEERRRQEEE--RTKRDAEEKRRQEEGYYSRLEAERRR 1676
+ +LEE++K+ E R +EEE+RR++EE R R+ EEKRR +E E ERRR
Sbjct: 559 QEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKE------EIERRR 612
Query: 1677 QHDEAARRLLEPEAPGLCRPPLPRDYEPPSPSPAPGAPPPPPQRNASYLKTQVLSPDSLF 1736
EAA + + GL D + P P + A +L V +
Sbjct: 613 A--EAAEKRQKMPEDGL------SDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVK 664
Query: 1737 TAKFVA----YNEEEEEEDCSLAGPNS----YPGSTGAAVGAHDACRDAKEKRSKSQDAD 1788
+ A + E+ ++ G S P ++ V A + R+ K K
Sbjct: 665 STHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPA-EGVRNIKSMWEKGNVFS 723
Query: 1789 SPGSSGAPENLT 1800
SP ++G P T
Sbjct: 724 SPTAAGTPNKET 735
Score = 60.5 bits (145), Expect = 1e-08
Identities = 69/300 (23%), Positives = 128/300 (42%), Gaps = 31/300 (10%)
Query: 1406 AERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEK 1465
A +R ++ + + + R +ER R+++E+E LGQ+ Q A S +
Sbjct: 26 AYQRNDDDEEEAARERRRRARQERLRQKQEEE-SLGQVTDQVEVNAQNSVPDEEAKTTTT 84
Query: 1466 PSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEK 1525
+ ++ E E +++ R +R LQ ++E DP DA L
Sbjct: 85 NTQVEGDDEAAFLERLARREERRQKR--LQEALERQKEF--------DPTITDASLSLPS 134
Query: 1526 QQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKR----LQESKQKDEDDEE 1581
++ + D E E + K + E + + +QK +E+K++D++ EE
Sbjct: 135 RRMQN--DTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEE 192
Query: 1582 EEDD--------DVDTMLIMQRLEAERRARTAMPA-----ISVLDLLQDEERRR-QQQLE 1627
EE++ + ++++ E + T + + IS + Q+EER + ++
Sbjct: 193 EEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEIS 252
Query: 1628 EMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLE 1687
K E ED+ R E ER R E E +R E+ ++ +R+EAE + E RR E
Sbjct: 253 HHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAE 312
Score = 39.3 bits (90), Expect = 0.036
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 16/152 (10%)
Query: 1551 EESDRLRKLMLEWQFQKRLQESK---QKDEDDEEEEDDDVDTMLIMQRLEAERRAR---- 1603
++ +R R+L + + + RL+ + Q+++DDEEE + +RL ++
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 1604 -TAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQ 1662
T ++ + + DEE + ++ E +D A E R+EE R KR E RQ
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQV---EGDDEAAFLERLARREERRQKRLQEALERQ 118
Query: 1663 EEGYYSRLEA-----ERRRQHDEAARRLLEPE 1689
+E + +A RR Q+D A E E
Sbjct: 119 KEFDPTITDASLSLPSRRMQNDTAENETTEKE 150
Score = 31.2 bits (69), Expect = 9.7
Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 6/56 (10%)
Query: 1615 LQDEERRRQ---QQLEEMR---KREAEDRARQEEERRRQEEERTKRDAEEKRRQEE 1664
+ D ERRR+ Q+ EEMR +R A R +EE +E R R +++QEE
Sbjct: 1 MDDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEE 56
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 70.5 bits (171), Expect = 1e-11
Identities = 83/353 (23%), Positives = 145/353 (41%), Gaps = 28/353 (7%)
Query: 1387 LPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQE-RKL-GQMR 1444
L P Q GL S E+ W+E+E L+ E ER+R+E R+L + +
Sbjct: 177 LAQDPQHEQGGLESRPCLDQNGHPGEDKPTWHEEEPNPLDSEEERRRQEDYWRELEAKCK 236
Query: 1445 TQSLNPAPFSPLTAQQMKPEKPSTLQ--RPQETVIRELQPQQQPRTIERRDLQYITVSKE 1502
Q A L Q+++ + + R QE + E + Q+ P ER +E
Sbjct: 237 RQKAEAAEKRRLEEQRLQALERRLWEENRRQELLEEEGEGQEPPLEAER-------APRE 289
Query: 1503 ELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLE 1562
E SL W+ + + E+++++ + + + Q++ R EE RL + +
Sbjct: 290 EQQR--SLEAPGWEDAERREREERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRRQ 347
Query: 1563 WQFQKRLQESKQKDEDDEEE-----EDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQD 1617
+ + R E ++ E++E E E + + + LE R + L +
Sbjct: 348 EEEEGRCAEELKRQEEEEAEGWEELEQQEAEVQGPPEALEETGEGRRGAEE----EDLGE 403
Query: 1618 EERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRL--EAERR 1675
EE Q LE+ R + +E + E R +++ER K + + + +E G EAERR
Sbjct: 404 EEEEGQAHLEDWRGQLSE--LLNDFEERLEDQERLKPEGQREHSEEPGICEEQNPEAERR 461
Query: 1676 RQHDEAARRLLEPEAPGLCRPPLPRDYEP--PSPSPAPGAPPPPPQRNASYLK 1726
R+ + + PG D EP P A PP ++ A+ L+
Sbjct: 462 REQQGRSGDFQGADRPGPEEKREEGDTEPLLKQEGPVEAAQPPVERKEAAALE 514
Score = 47.4 bits (111), Expect = 1e-04
Identities = 76/343 (22%), Positives = 133/343 (38%), Gaps = 60/343 (17%)
Query: 1390 PPSANQIGLPSAQVAAAERRKREEHQRWY-EKEKARLEEE---RERKRREQERKLGQMRT 1445
P Q L + AERR+REE +R E+E+ RL+ + ER+R E++ +L + R
Sbjct: 287 PREEQQRSLEAPGWEDAERREREERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRR 346
Query: 1446 QSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELS 1505
Q A+++K ++ + +E +E + Q P +E +E+L
Sbjct: 347 QEEEEGR----CAEELKRQEEEEAEGWEELEQQEAEVQGPPEALEETGEGRRGAEEEDLG 402
Query: 1506 SGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQF 1565
E++ Q H+ D ++ EL + + E+
Sbjct: 403 EE----------------EEEGQAHLEDWRG-QLSELLNDFEERLED------------- 432
Query: 1566 QKRLQESKQKDEDDE----EEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERR 1621
Q+RL+ Q++ +E EE++ + + +R E + R+ A D EE+R
Sbjct: 433 QERLKPEGQREHSEEPGICEEQNPEAE-----RRREQQGRSGDFQGA----DRPGPEEKR 483
Query: 1622 RQQQLEEMRKREAEDRARQEE-ERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDE 1680
+ E + K+E A Q ER+ R EE R QE + Q
Sbjct: 484 EEGDTEPLLKQEGPVEAAQPPVERKEAAALEQGRKVEELRWQEVDERQTMPRPYTFQVSS 543
Query: 1681 AARRLLEPE--------APGLCRPPLPRDYEPPSPSPAPGAPP 1715
+++L P+ A P++ + P SP A P
Sbjct: 544 GGKQILFPKVNLSPVTPAKDTGLTAAPQEPKAPKASPVQHALP 586
Score = 31.6 bits (70), Expect = 7.4
Identities = 87/426 (20%), Positives = 145/426 (34%), Gaps = 47/426 (11%)
Query: 1107 PMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSPES-PQLPWAEYSEPKKLPGDDRLMKN 1165
P Q+ SD G+ + +E + S E+ PQ P A E K P + +
Sbjct: 723 PAWQKFSDG-GTETSKQSTEAESIRKRPMLGPSEETAPQPPPAGVRELGKGPEKSEMHRE 781
Query: 1166 RADHRSSPNVANQPPS---------PGGKSAYASGTTAKITSVSTGNLCTEEQTPPPRPE 1216
AD A PS P A+ TT+ + + G + P +
Sbjct: 782 PADTTEGCKFAKDLPSFLVPSLPYPPQKVVAHTEFTTSSDSETANGIAKPDPVMPGGEEK 841
Query: 1217 AYPIPTQTYTREY-FTFPASKSQDRMAPPQNQWPNYEEKPHMHT----DSNHSSIAIQRV 1271
A P + Y F + ++ ++K H T D+ + R
Sbjct: 842 ASPFGIKLRRTNYSLRFNCDQQAEQK----------KKKRHSSTGDSADAGPPAAGSARG 891
Query: 1272 TRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSL----DSSTSSQEHLNHSSKS 1327
+ E + L + R +A R+ ++ ++S + SSQ K+
Sbjct: 892 EKEMEGVALKHGPSLPQERKQAPSTRRDSAEPSSSRSVPVAHPGPPPASSQTPAPEHDKA 951
Query: 1328 VTPASTLTKSGPGRWKTPAAIPATPVA-VSQPIRTDLPP-----PPPPPPVHYAGDFDGM 1381
K T PA+P++ +S+P +L P P P D +
Sbjct: 952 ANKMPLAQKPALAPKPTSQTPPASPLSKLSRPYLVELLSRRAGRPDPEPSEPSKEDQESS 1011
Query: 1382 SMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLG 1441
P PP P + + A ER+ ++EK E RK +
Sbjct: 1012 DRRPPSPPGPEERKGQKRDEEEEATERKPASPPLPATQQEKPSQTPEAGRKEKPM----- 1066
Query: 1442 QMRTQSLNPAPFSPLTAQQMKPEKP--STLQRPQETVIRELQPQQQPRTIERRDLQYITV 1499
QS + S LT ++++ +P TL ++ RE Q ++ R R Q +
Sbjct: 1067 ---LQSRHSLDGSKLT-EKVETAQPLWITLALQKQKGFREQQATREERKQAREAKQAEKL 1122
Query: 1500 SKEELS 1505
SKE +S
Sbjct: 1123 SKENVS 1128
>gi|93204861 protein phosphatase 1, regulatory (inhibitor) subunit 9A
[Homo sapiens]
Length = 1098
Score = 70.5 bits (171), Expect = 1e-11
Identities = 38/91 (41%), Positives = 59/91 (64%), Gaps = 4/91 (4%)
Query: 1005 EIITVTLKK-QNGMGLSIVA---AKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1060
E+ V L+K ++G+G+SI+ AG +KLGI+VK+V +GGAA DGR+ DQ++ V
Sbjct: 501 ELFPVELEKDEDGLGISIIGMGVGADAGLEKLGIFVKTVTEGGAAQRDGRIQVNDQIVEV 560
Query: 1061 DGRSLVGLSQERAAELMTRTSSVVTLEVAKQ 1091
DG SLVG++Q AA ++ T V + ++
Sbjct: 561 DGISLVGVTQNFAATVLRNTKGNVRFVIGRE 591
Score = 34.3 bits (77), Expect = 1.1
Identities = 69/360 (19%), Positives = 136/360 (37%), Gaps = 59/360 (16%)
Query: 1390 PPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQS-- 1447
P +++ +Q ERR+RE ++ Y + A +E E E+E ++G + S
Sbjct: 593 PGQVSEVAQLISQTLEQERRQRELLEQHYAQYDADDDETGEYATDEEEDEVGPVLPGSDM 652
Query: 1448 --------LNPAPFSPLTAQQMK-PEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYIT 1498
N FSP K K LQ E+Q + +
Sbjct: 653 AIEVFELPENEDMFSPSELDTSKLSHKFKELQIKHAVTEAEIQKLKTKLQAAENEKVRWE 712
Query: 1499 VSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRK 1558
+ K +L + + + +E Q H V ++ ++E QS+ ++ ++ +K
Sbjct: 713 LEKTQLQQNIEENKERMLKLESYWIEAQTLCHTV---NEHLKETQSQYQALEKKYNKAKK 769
Query: 1559 LMLEWQ-----FQKRLQESKQKDEDDEEEEDDDVDTMLIMQR-LEAE------------- 1599
L+ ++Q F KR + ++K ED E+ +V + + R LEAE
Sbjct: 770 LIKDFQQKELDFIKRQEAERKKIEDLEKAHLVEVQGLQVRIRDLEAEVFRLLKQNGTQVN 829
Query: 1600 -----RRARTAMPAISVLDLLQDEERRRQQ--------------QLEEMRKREAEDRARQ 1640
RT++ +S D +++ + ++ + E + + + RA+
Sbjct: 830 NNNNIFERRTSLGEVSKGDTMENLDGKQTSCQDGLSQDLNEAVPETERLDSKALKTRAQL 889
Query: 1641 EEERRRQEEERTK-------RDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEAPGL 1693
+ RRQ RT+ D E+ ++ ++ + + + EP+ PGL
Sbjct: 890 SVKNRRQRPSRTRLYDSVSSTDGEDSLERKNFTFNDDFSPSSTSSADLSGLGAEPKTPGL 949
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 69.3 bits (168), Expect = 3e-11
Identities = 69/266 (25%), Positives = 123/266 (46%), Gaps = 17/266 (6%)
Query: 1428 ERERKRREQERK-----LGQMRTQSLN-PAPFSPLTAQQMKPEKPSTLQRPQETVIRELQ 1481
+ E KRR+Q K L + + LN P+ S ++ K EK + R + L
Sbjct: 197 DEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFR--RFPVAPLI 254
Query: 1482 PQQQPRTIERRDLQYITVSKEE---LSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKE 1538
P I + D+ I + +++ +S S D K+ +EK +K+++ ++ +E
Sbjct: 255 PYP---LITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRE 311
Query: 1539 IQ-ELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLE 1597
+ E + + +R E +R R+ E + ++ + + +D D +E D D D R +
Sbjct: 312 RERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDR-D 370
Query: 1598 AERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAE-DRARQEEERRRQEEERTKRDA 1656
ER + + +D ER R+++ E R+RE E +R R+ E R +E ER K
Sbjct: 371 RERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKK 430
Query: 1657 EEKRRQEEGYYSRLEAERRRQHDEAA 1682
++ EE Y R + ER+ + EAA
Sbjct: 431 RDREEDEEDAYERRKLERKLREKEAA 456
Score = 67.8 bits (164), Expect = 9e-11
Identities = 88/360 (24%), Positives = 160/360 (44%), Gaps = 63/360 (17%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKR-REQERKLGQMRTQSLNPAPFSPLTAQQMKPEK 1465
ER + E +R E+E+ R E ERER+R RE+ER+ + R + + E+
Sbjct: 394 ERERERERERERERERER-EREREREREREREREKDKKRDRE--------------EDEE 438
Query: 1466 PSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEK 1525
+ +R E +RE + Q R ++ +++ ++E ++++A+ + E+
Sbjct: 439 DAYERRKLERKLREKEAAYQER-LKNWEIRERKKTRE------------YEKEAEREEER 485
Query: 1526 QQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDD 1585
+++M +K ++E D ++ R L+ + + R +E + DE D + E +
Sbjct: 486 RREMA---KEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEM-EADERDRKREKE 541
Query: 1586 DVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERR 1645
+++ I QRL AE P + + Q+ ERRRQ Q+++ + E E+ +QE+E +
Sbjct: 542 ELEE--IRQRLLAEGHPD---PDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEK 596
Query: 1646 RQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEAPG---LCRPPLPRDY 1702
R+E + EE+ Q+ L +A P PG C +P +
Sbjct: 597 REE----PMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHEN 652
Query: 1703 EPPSPSPAP-----------GAPPPPPQRNASYLKTQVLSPDSLFTAKFVAYNEEEEEED 1751
P P GA P Q N+ +K + L DS+F KF E+E+ +D
Sbjct: 653 SPDQQQPEEHRPKIGLSLKLGASNSPGQPNS--VKRKKLPVDSVFN-KF----EDEDSDD 705
Score = 67.4 bits (163), Expect = 1e-10
Identities = 78/358 (21%), Positives = 145/358 (40%), Gaps = 64/358 (17%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1466
E+ K+E+ ++ EKE+ E ERER+R +ER+ + R + ++ + E+
Sbjct: 294 EKGKKEKERQEIEKERRERERERERERERREREREREREREREKE-----KERERERERD 348
Query: 1467 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQ 1526
R +E + + + R ER + S+ S D +R+ + + E++
Sbjct: 349 RDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERE 408
Query: 1527 QQMHIVDMLSKEIQ---ELQSKPDRSAEESDRLRKLMLE----------------WQFQK 1567
++ +E + E K DR +E D + LE W+ ++
Sbjct: 409 REREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRE 468
Query: 1568 RLQESKQKDEDDEEEE-------------------DDDVDTMLIMQRLEAERRARTAMPA 1608
R + + + E + EEE DDD D + ++R R
Sbjct: 469 RKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDRE-- 526
Query: 1609 ISVLDLLQDEERRRQQQLEEMRKR---------EAE-DRARQEEERRRQEEERTKRDAEE 1658
++ + + +R +++LEE+R+R +AE R QE ERRRQ + + + ++EE
Sbjct: 527 -KEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEE 585
Query: 1659 KRRQEEGYYSRLEAERRRQHDEAARRLLEPEAPGLCRPPLPRDYEPPSPSPAPGAPPP 1716
+ +++ E+ + +E EPE +P L PS S A G P
Sbjct: 586 EEEEKQ--------EKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATP 635
Score = 45.8 bits (107), Expect = 4e-04
Identities = 57/245 (23%), Positives = 102/245 (41%), Gaps = 36/245 (14%)
Query: 1465 KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLE 1524
+P T+ E + E + +++ + I+ I EL++ S ++ KEK E
Sbjct: 184 RPETVTNDDEEALDE-ETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKE 242
Query: 1525 KQQQMHIV------DMLSKE----IQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQ 1574
+ V +++KE I+ + K D + E + R K+L+E K
Sbjct: 243 DIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDT------HKKLEEEKG 296
Query: 1575 KDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREA 1634
K E + +E + + + E ERR R + ++ ER R+++ E R+RE
Sbjct: 297 KKEKERQEIEKERRERERERERERERRER---------EREREREREREKEKERERERER 347
Query: 1635 E-DRAR---------QEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARR 1684
+ DR R +E +R R E + R+ + R +E+ E ER R+ + R
Sbjct: 348 DRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERER 407
Query: 1685 LLEPE 1689
E E
Sbjct: 408 ERERE 412
Score = 34.3 bits (77), Expect = 1.1
Identities = 38/188 (20%), Positives = 78/188 (41%), Gaps = 31/188 (16%)
Query: 1398 LPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLT 1457
L + A ER K E + + + E ERE +RR + K + + L
Sbjct: 450 LREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDD--- 506
Query: 1458 AQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR 1517
K + S LQ+ +E++ ++ R E+ +L+ I ++ L + PD +
Sbjct: 507 RDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEI---RQRLLAEGHPDPDAELQ 563
Query: 1518 DAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDE 1577
+++ E+++Q +++ +P+ EE ++ QE ++K E
Sbjct: 564 RMEQEAERRRQ-----------PQIKQEPESEEEEEEK--------------QEKEEKRE 598
Query: 1578 DDEEEEDD 1585
+ EEE++
Sbjct: 599 EPMEEEEE 606
Score = 31.2 bits (69), Expect = 9.7
Identities = 24/114 (21%), Positives = 56/114 (49%), Gaps = 3/114 (2%)
Query: 121 DREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQAS 180
DRE R +N++ + + + ++E+E + + ++E++ +++RE+E R+
Sbjct: 370 DRE-RSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKD 428
Query: 181 DKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQ 234
K DR ED R ++ E ++ + N E + +R++ ++ EK +
Sbjct: 429 KKRDREEDEEDAYERRKLERKLRE-KEAAYQERLKNWE-IRERKKTREYEKEAE 480
>gi|112382257 InaD-like [Homo sapiens]
Length = 1801
Score = 69.3 bits (168), Expect = 3e-11
Identities = 37/88 (42%), Positives = 54/88 (61%), Gaps = 6/88 (6%)
Query: 1005 EIITVTLKKQ--NGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDG 1062
EI V L+K+ G+GLSIV + G+++ +VKGGAAD+DGRL GDQ+LSV+G
Sbjct: 1530 EIFPVDLQKKAGRGLGLSIVGKRNGS----GVFISDIVKGGAADLDGRLIQGDQILSVNG 1585
Query: 1063 RSLVGLSQERAAELMTRTSSVVTLEVAK 1090
+ SQE A ++ +V LE+ +
Sbjct: 1586 EDMRNASQETVATILKCAQGLVQLEIGR 1613
Score = 54.7 bits (130), Expect = 8e-07
Identities = 27/79 (34%), Positives = 47/79 (59%), Gaps = 5/79 (6%)
Query: 1015 NGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAA 1074
+G+G IV K +G + V+++V GG AD DGRL GD +L + G ++ G++ E+ A
Sbjct: 256 SGLGFGIVGGKTSG-----VVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQGMTSEQVA 310
Query: 1075 ELMTRTSSVVTLEVAKQGA 1093
+++ + V + VA+ A
Sbjct: 311 QVLRNCGNSVRMLVARDPA 329
Score = 54.7 bits (130), Expect = 8e-07
Identities = 44/163 (26%), Positives = 70/163 (42%), Gaps = 26/163 (15%)
Query: 1012 KKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQE 1071
K +NG+GLS+ K + ++ I+V + G A DGR+ GD+LL ++ + L G S +
Sbjct: 1244 KDKNGLGLSLAGNKD--RSRMSIFVVGINPEGPAAADGRMRIGDELLEINNQILYGRSHQ 1301
Query: 1072 RAAELM-TRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSG----------- 1119
A+ ++ T S V + + + A+ T PS I D+ G+
Sbjct: 1302 NASAIIKTAPSKVKLVFIRNEDAVNQMAVTPFPVPSSSPSSIEDQSGTEPISSEEDGSVE 1361
Query: 1120 ---KPRPKSEGFEL---------YNNSTQNGSPESPQLPWAEY 1150
K P+SE F+L Y S E P P + Y
Sbjct: 1362 VGIKQLPESESFKLAVSQMKQQKYPTKVSFSSQEIPLAPASSY 1404
Score = 53.9 bits (128), Expect = 1e-06
Identities = 43/130 (33%), Positives = 60/130 (46%), Gaps = 11/130 (8%)
Query: 999 PLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLL 1058
P+ E+I K ++G+GLSIV K + I + V + GAA DGRL AGDQ+L
Sbjct: 1429 PIVPGQEMIIEISKGRSGLGLSIVGGKDTPLN--AIVIHEVYEEGAAARDGRLWAGDQIL 1486
Query: 1059 SVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQR------- 1111
V+G L S E A + +T V L V + A Y L P + ++
Sbjct: 1487 EVNGVDLRNSSHEEAITALRQTPQKVRLVVYRDEAHYRDEENLEIFPVDLQKKAGRGLGL 1546
Query: 1112 --ISDRRGSG 1119
+ R GSG
Sbjct: 1547 SIVGKRNGSG 1556
Score = 51.6 bits (122), Expect = 7e-06
Identities = 35/117 (29%), Positives = 60/117 (51%), Gaps = 7/117 (5%)
Query: 976 WTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIY 1035
WT D+ S + ++AQ ++ E I + G+G S+VA + K+ I+
Sbjct: 110 WTPKLGNEDFNSVI----QQMAQG--RQIEYIDIERPSTGGLGFSVVALRSQNLGKVDIF 163
Query: 1036 VKSVVKGGAADVDGRLAAGDQLLSVDGRSL-VGLSQERAAELMTRTSSVVTLEVAKQ 1091
VK V G AD D RL DQ+L+++ L +S ++A L+ +T+ + L VA++
Sbjct: 164 VKDVQPGSVADRDQRLKENDQILAINHTPLDQNISHQQAIALLQQTTGSLRLIVARE 220
Score = 47.4 bits (111), Expect = 1e-04
Identities = 27/91 (29%), Positives = 49/91 (53%), Gaps = 4/91 (4%)
Query: 1005 EIITVTLKKQNG--MGLSIVAAKGAGQ--DKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1060
E V L +++G +G+ IV G + GIYVKS++ G AA +G + D++++V
Sbjct: 362 ETYNVELVRKDGQSLGIRIVGYVGTSHTGEASGIYVKSIIPGSAAYHNGHIQVNDKIVAV 421
Query: 1061 DGRSLVGLSQERAAELMTRTSSVVTLEVAKQ 1091
DG ++ G + E++ VV L + ++
Sbjct: 422 DGVNIQGFANHDVVEVLRNAGQVVHLTLVRR 452
Score = 44.3 bits (103), Expect = 0.001
Identities = 20/86 (23%), Positives = 43/86 (50%)
Query: 1003 EPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDG 1062
EP + + + + +G+SI +G+ + +++ + G A +L GD+++S++G
Sbjct: 1673 EPRTVEINRELSDALGISIAGGRGSPLGDIPVFIAMIQASGVAARTQKLKVGDRIVSING 1732
Query: 1063 RSLVGLSQERAAELMTRTSSVVTLEV 1088
+ L GLS L+ + L+V
Sbjct: 1733 QPLDGLSHADVVNLLKNAYGRIILQV 1758
Score = 40.0 bits (92), Expect = 0.021
Identities = 32/135 (23%), Positives = 54/135 (40%), Gaps = 14/135 (10%)
Query: 1004 PEIITVTLKKQNGMGLSIVAAKGA------GQDKLGIYVKSVVKGGAADVDGRLAAGDQL 1057
P I+ + + +G+SIV + G++ GI++K V++ A L GD++
Sbjct: 1066 PRIVEIFREPNVSLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTNALKTGDKI 1125
Query: 1058 LSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAI------YHGLATLL--NQPSPMM 1109
L V G L S A E + + V V + H A + NQ
Sbjct: 1126 LEVSGVDLQNASHSEAVEAIKNAGNPVVFIVQSLSSTPRVIPNVHNKANKITGNQNQDTQ 1185
Query: 1110 QRISDRRGSGKPRPK 1124
++ R+G+ P K
Sbjct: 1186 EKKEKRQGTAPPPMK 1200
Score = 39.3 bits (90), Expect = 0.036
Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 13/108 (12%)
Query: 982 GADYESHLLRENTELAQP--LRKEPEIITV-TLKKQNGMGLSIVAAKGAGQDKLGIYVKS 1038
G DYE + +T++A L+K +++ + TL+ +G+ + + G Y+ S
Sbjct: 536 GPDYEVMVATLDTQIADDAELQKYSKLLPIHTLR----LGVEVDSFDGHH------YISS 585
Query: 1039 VVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTL 1086
+V GG D G L D+LL V+G L G S+ A + TL
Sbjct: 586 IVSGGPVDTLGLLQPEDELLEVNGMQLYGKSRREAVSFLKEVPPPFTL 633
>gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo
sapiens]
Length = 817
Score = 68.6 bits (166), Expect = 5e-11
Identities = 68/213 (31%), Positives = 102/213 (47%), Gaps = 25/213 (11%)
Query: 890 EPFIPTDLIENVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPN 949
E F DL++ V+ ++ A S E +++ D + P+ PE G IP
Sbjct: 385 EDFSEADLVD--VSAYSGLGEDSAGSALEEDDEDDEEDGEPPYE-PESGCV-----EIP- 435
Query: 950 GLQEFLDPLCQRGFCRLIPHTRSPGTWTIYFEGADYESHL-----LRENTELAQPLRKEP 1004
GL E DP R I + +P + DY+ + + E R E
Sbjct: 436 GLSEEEDPAPSRK----IHFSTAPIQVFSTYSNEDYDRRNEDVDPMAASAEYELEKRVER 491
Query: 1005 -EIITVTLKKQN-GMGLSIVAAKGAGQD----KLGIYVKSVVKGGAADVDGRLAAGDQLL 1058
E+ V L+K + G+G+SI+ GAG D KLGI+VK+V +GGAA DGR+ D L+
Sbjct: 492 LELFPVELEKDSEGLGISIIGM-GAGADMGLEKLGIFVKTVTEGGAAHRDGRIQVNDLLV 550
Query: 1059 SVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQ 1091
VDG SLVG++Q AA ++ T V + ++
Sbjct: 551 EVDGTSLVGVTQSFAASVLRNTKGRVRFMIGRE 583
Score = 35.8 bits (81), Expect = 0.39
Identities = 73/338 (21%), Positives = 117/338 (34%), Gaps = 27/338 (7%)
Query: 1279 REDKAYQLERHRIEAAMDRKSDSDMWINQSSS----LDSSTSSQEHLNHSSKSVTPASTL 1334
+E A +L R DRK D + N S+ LD+ S ++ S A +
Sbjct: 163 KEAAARRLLRQERAGLQDRKLDVVVRFNGSTEALDKLDADAVSPT-VSQLSAVFEKADSR 221
Query: 1335 T--KSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPS 1392
T GPG + VS+ R PPPPPPP +GD P P
Sbjct: 222 TGLHRGPGLPRAAGVPQVNSKLVSKRSRVFQPPPPPPPAP--SGDAPAEKERCPAGQQPP 279
Query: 1393 ANQIGLPSAQVAAAERRK----REEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSL 1448
+++ E RK E E E A E + + G +
Sbjct: 280 QHRVAPARPPPKPREVRKIKPVEVEESGESEAESAPGEVIQAEVTVHAALENGSTVATAA 339
Query: 1449 NPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTI-ERRDLQYITVSKEELSSG 1507
+PAP P AQ ++ + + P+ V P P + E + + ++S+
Sbjct: 340 SPAPEEP-KAQAAPEKEAAAVAPPERGVGNGRAPDVAPEEVDESKKEDFSEADLVDVSAY 398
Query: 1508 DSLSPD----PWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEW 1563
L D + D ++ E + + + EI L + D + RK+
Sbjct: 399 SGLGEDSAGSALEEDDEDDEEDGEPPYEPESGCVEIPGLSEEEDPAPS-----RKIHFS- 452
Query: 1564 QFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERR 1601
+Q +D + ++DVD M E E+R
Sbjct: 453 --TAPIQVFSTYSNEDYDRRNEDVDPMAASAEYELEKR 488
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 68.2 bits (165), Expect = 7e-11
Identities = 83/332 (25%), Positives = 143/332 (43%), Gaps = 48/332 (14%)
Query: 1464 EKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKL 1523
++PST Q + IR+ QP ++ I+ +D +I ++++ D + + +E+
Sbjct: 276 QRPSTEQLLKHPFIRD-QPNERQVRIQLKD--HIDRTRKKRGEKDETEYEYSGSEEEEEE 332
Query: 1524 EKQQQ---MHIVDM-----LSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQK 1575
+Q+ IV++ L ++ LQ + + E S+ LR+ L + Q R QE ++
Sbjct: 333 VPEQEGEPSSIVNVPGESTLRRDFLRLQQE---NKERSEALRRQQLLQEQQLREQEEYKR 389
Query: 1576 DEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAE 1635
E ++ + + E +RR R A Q+ E+RR++Q E+ R E E
Sbjct: 390 QLLAERQKRIEQQKEQRRRLEEQQRREREARRQ-------QEREQRRREQEEKRRLEELE 442
Query: 1636 DRARQEEERRRQEEERTK---------RDAEEKRRQEEGYYSRL-------------EAE 1673
R ++EEERRR EEE+ + R EE++R E +L E E
Sbjct: 443 RRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREME 502
Query: 1674 RRRQHDEAARRLLEPEAPGLCRPPLPRDYEPPSPSPAPGAPPPPPQRNASYLKTQVLSPD 1733
RQ + R+L + +A L L D+ P P + PPPPQ+ S P
Sbjct: 503 EHRQAERLQRQLQQEQAYLL---SLQHDHRRPHPQHS--QQPPPPQQERSKPSFHAPEPK 557
Query: 1734 SLFTAKFVAYNEEEEEEDCSLAGPNSYPGSTG 1765
+ + A E+ + + P + TG
Sbjct: 558 AHYEPADRAREVEDRFRKTNHSSPEAQSKQTG 589
Score = 42.0 bits (97), Expect = 0.005
Identities = 37/145 (25%), Positives = 71/145 (48%), Gaps = 11/145 (7%)
Query: 1407 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1466
+RR+ EE QR + +AR ++ERE++RREQE K R + L ++ + EK
Sbjct: 405 QRRRLEEQQR--REREARRQQEREQRRREQEEK---RRLEELERRRKEEEERRRAEEEK- 458
Query: 1467 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQ 1526
++R QE + R+L+ +Q+ + ++ L +E+ + + + E+L++Q
Sbjct: 459 RRVEREQEYIRRQLEEEQRHLEVLQQQL-----LQEQAMLLECRWREMEEHRQAERLQRQ 513
Query: 1527 QQMHIVDMLSKEIQELQSKPDRSAE 1551
Q +LS + + P S +
Sbjct: 514 LQQEQAYLLSLQHDHRRPHPQHSQQ 538
Score = 33.9 bits (76), Expect = 1.5
Identities = 67/326 (20%), Positives = 127/326 (38%), Gaps = 77/326 (23%)
Query: 1409 RKREEHQRWYEKEKA-RLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPS 1467
R++EE++R E+ R+E+++E++RR +E Q + E+ +
Sbjct: 382 REQEEYKRQLLAERQKRIEQQKEQRRRLEE----------------------QQRREREA 419
Query: 1468 TLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQ 1527
Q+ +E RE + +++ +ERR KEE + + K ++E++Q
Sbjct: 420 RRQQEREQRRREQEEKRRLEELERR-------RKEEEERRRA-------EEEKRRVEREQ 465
Query: 1528 QMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDV 1587
+ +I L +E + L+ + +E L L W + ++E +Q
Sbjct: 466 E-YIRRQLEEEQRHLEVLQQQLLQEQAML--LECRW---REMEEHRQ------------- 506
Query: 1588 DTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQE----EE 1643
AER R + L LQ + RR Q + ++R++ E
Sbjct: 507 ----------AERLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFHAPEP 556
Query: 1644 RRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEAPGLCRPPLPRDYE 1703
+ E R+ E++ R+ +S EA+ ++ R+LEP P + E
Sbjct: 557 KAHYEPADRAREVEDRFRKTN--HSSPEAQSKQ-----TGRVLEPPVPSRSESFSNGNSE 609
Query: 1704 PPSPSPAPGAPPPPPQRNASYLKTQV 1729
P+ A P + + LK V
Sbjct: 610 SVHPALQRPAEPQVQWSHLASLKNNV 635
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 67.8 bits (164), Expect = 9e-11
Identities = 74/316 (23%), Positives = 147/316 (46%), Gaps = 53/316 (16%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
Q A AE+ +E+ Q E + + E E +Q+++L Q + + L Q+
Sbjct: 2304 QRALAEKMLKEKMQAVQEATRLKAEAEL----LQQQKELAQEQARRL----------QED 2349
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
K + L + R L+ ++Q + + + + + E+S + + + +R K+
Sbjct: 2350 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2409
Query: 1522 KLEKQQQMHIVDMLSKE----IQELQSKPDRSAEESDRLRKLM--LEWQFQKRLQESKQK 1575
E +++H ++ ++E +Q L+ + +S +++RLR+ + LE + +K QE+K
Sbjct: 2410 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2469
Query: 1576 DEDDEEEED------------------DDVDTMLIMQRLEAERRARTAM---PAISVLDL 1614
EE + + D++L +R + +A+ ++
Sbjct: 2470 QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ 2529
Query: 1615 LQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAER 1674
L++E++R+QQQ+E+ R+R A EE RRRQ E AEE R+++ +LE +R
Sbjct: 2530 LREEQQRQQQQMEQERQRLV---ASMEEARRRQHE------AEEGVRRKQEELQQLEQQR 2580
Query: 1675 RRQHD---EAARRLLE 1687
R+Q + E +RL E
Sbjct: 2581 RQQEELLAEENQRLRE 2596
Score = 65.1 bits (157), Expect = 6e-10
Identities = 77/315 (24%), Positives = 134/315 (42%), Gaps = 36/315 (11%)
Query: 1401 AQVAAAERRKREEHQRWYEKEKA----RLEEERERKRREQERKLGQMRTQSLNPAPFSPL 1456
A++A E+ E R +++A RLEE+ + + + E +L Q+R S S L
Sbjct: 1852 AEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKAS-----DSEL 1906
Query: 1457 TAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK 1516
Q+ E +R E I L+ + + +L+ EL S + D +
Sbjct: 1907 ERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELEL------ELGRIRSNAEDTLR 1960
Query: 1517 RDAKEKLEKQQQMHIV---DMLSKEIQELQSKPDRSAEESDRLRKLMLEW--QFQKRLQE 1571
+ +LE +Q + + +E +E K + EE+ R RK LE + + +++E
Sbjct: 1961 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2020
Query: 1572 SKQKDEDDEEEEDDDVDTM--LIMQRLEAERRA-------------RTAMPAISVLDLLQ 1616
+++ E E+E + +RL+AE +A +T SVLD L+
Sbjct: 2021 ARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR 2080
Query: 1617 DEERRRQQQLEEMRKREAEDRARQEEERRRQEE-ERTKRDAEEKRRQEEGYYSRLEAERR 1675
E ++ EE + + + RR+ EE ER K+ AEE+ + + E R+
Sbjct: 2081 GEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK 2140
Query: 1676 RQHDEAARRLLEPEA 1690
EAARR +A
Sbjct: 2141 EAEQEAARRAQAEQA 2155
Score = 63.9 bits (154), Expect = 1e-09
Identities = 79/314 (25%), Positives = 139/314 (44%), Gaps = 41/314 (13%)
Query: 1395 QIGLPSAQVAAAERRKREEHQRWYEKEKARLEE---ERERKRREQERKLGQMRTQSLNPA 1451
Q+ AQ A R+ +E Q+ ++E R EE + ++++R + +L Q+R S
Sbjct: 1374 QLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1433
Query: 1452 PFSPLTAQQMKPEKPSTLQRPQET-VIR-ELQPQQQPRTIERRDLQYITVSKEELSSGDS 1509
A+Q + + S L+ +E V+R +L+ ++ R +LQ + EE +
Sbjct: 1434 QAK---ARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQ-- 1488
Query: 1510 LSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQ---ELQSKPDRSAE---ESDRLRKLMLEW 1563
KR A+E+ E+ ++ + D ++ Q EL S+ AE E R + + E
Sbjct: 1489 ------KRQAQEEAERLRRQ-VQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1541
Query: 1564 QFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPA--------------I 1609
+ Q E + + + E V + EAE +++ A A +
Sbjct: 1542 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1601
Query: 1610 SVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSR 1669
+V L ++ ERR QQQ E R RE +R + + + E R + AEE +Q+ S
Sbjct: 1602 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQK----SL 1657
Query: 1670 LEAERRRQHDEAAR 1683
+AE +Q +EA R
Sbjct: 1658 AQAEAEKQKEEAER 1671
Score = 57.4 bits (137), Expect = 1e-07
Identities = 83/341 (24%), Positives = 138/341 (40%), Gaps = 77/341 (22%)
Query: 1409 RKREEHQRWYEKEKARLEEERERKRR-----EQERKLGQMRTQSLNPAPFSPLTAQQMKP 1463
R+ EE +R E+++A EERER E++R+L + Q+ Q +
Sbjct: 1342 RRMEEEERLAEQQRA---EERERLAEVEAALEKQRQLAEAHAQA----------KAQAER 1388
Query: 1464 EKPSTLQRPQETVIRE----LQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDA 1519
E QR QE V+R + QQQ R+I+ +LQ + S E + + +R
Sbjct: 1389 EAKELQQRMQEEVVRREEAAVDAQQQKRSIQE-ELQQLRQSSEAEIQAKARQAEAAERS- 1446
Query: 1520 KEKLEKQQQMHIVDM------------------LSKEIQELQSKPDRSAEESDRLRKLML 1561
+L ++++ +V + L +E +++ ++ EE++RLR+ +
Sbjct: 1447 --RLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1504
Query: 1562 EWQFQKRLQE----SKQKDEDDEEEEDDDVDTMLIMQRL---EAERRARTAMP--AISVL 1612
+ +KR E S+ K E + E L RL EAERR R A A V
Sbjct: 1505 DESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQ 1564
Query: 1613 DLLQDEERRRQQQLEEMR------------------------KREAEDRARQEEERRRQE 1648
L+ +R + +L+ R + EAE RA+Q+ E R
Sbjct: 1565 VALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAR 1624
Query: 1649 EERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
EE + + + E RL+AE Q A+ E +
Sbjct: 1625 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQ 1665
Score = 54.3 bits (129), Expect = 1e-06
Identities = 67/278 (24%), Positives = 118/278 (42%), Gaps = 51/278 (18%)
Query: 1406 AERRKREEHQRWYEKEKARLEE-ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPE 1464
AER+++ E E+ K R+ E R + R E++ + + + + + A Q K
Sbjct: 2370 AERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT 2429
Query: 1465 KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLE 1524
TL E+Q QQ ER + +E+ + +++AK
Sbjct: 2430 LVQTL---------EIQRQQSDHDAERLREAIAELEREK---------EKLQQEAKLLQL 2471
Query: 1525 KQQQMHIVDMLSKEIQELQSKPDRSAEESDRL---------RKLMLEWQFQKRLQESKQK 1575
K ++M V + +QE Q+ E D L K LE FQ + +++Q
Sbjct: 2472 KSEEMQTVQQ-EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL 2530
Query: 1576 DEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAE 1635
E+ + ++ Q++E ER+ A +E RRRQ + EE +R+ E
Sbjct: 2531 REEQQRQQ----------QQMEQERQRLVAS---------MEEARRRQHEAEEGVRRKQE 2571
Query: 1636 DRARQEEERRRQEE---ERTKRDAEEKRRQEEGYYSRL 1670
+ + E++RR+QEE E +R E+ + EE + + L
Sbjct: 2572 ELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2609
Score = 53.1 bits (126), Expect = 2e-06
Identities = 82/330 (24%), Positives = 141/330 (42%), Gaps = 47/330 (14%)
Query: 1398 LPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLT 1457
+P A A + R+E E E R E+ E +R ++ + ++ L +
Sbjct: 1236 MPLADSQAVREQLRQEQALLEEIE--RHGEKVEECQRFAKQYINAIKDYELQLVTYKAQL 1293
Query: 1458 AQQMKPEKPSTLQRPQETVIRELQPQQ----QPRTIERRDLQYITVSKEELSSGDSLSPD 1513
P K +Q E+VI+E + + T+ + +++I+ + + + L+ +
Sbjct: 1294 EPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLA-E 1352
Query: 1514 PWKRDAKEKL-------EKQQQMHIVDMLSKEIQELQSKP--DRSAEESDRLRKLMLEWQ 1564
+ + +E+L EKQ+Q+ +K E ++K R EE R + ++ Q
Sbjct: 1353 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQ 1412
Query: 1565 FQKR-LQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQ 1623
QKR +QE Q+ E E ++ EA R+R + + LQ E RQ
Sbjct: 1413 QQKRSIQEELQQLRQSSEAE-----IQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQ 1467
Query: 1624 Q-----QLEEMRKR----EAEDRARQEE----ERRRQEEERTKRDAE-----------EK 1659
+ +L+ +R R EA+ R QEE R+ Q+E + KR AE E
Sbjct: 1468 RGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1527
Query: 1660 RRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
R+++ LE E R Q +EA RRL + E
Sbjct: 1528 AREKQRALQALE-ELRLQAEEAERRLRQAE 1556
Score = 52.8 bits (125), Expect = 3e-06
Identities = 84/343 (24%), Positives = 145/343 (42%), Gaps = 71/343 (20%)
Query: 1406 AERRKREEHQRWYEKEKARLEEERE---RKRREQERKLGQMRTQSLNPAPFSPLTAQQMK 1462
AE + E+ ++ E+E ARL+ E +KR+E E +L ++R A L A + +
Sbjct: 1720 AETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR------AEMEVLLASKAR 1773
Query: 1463 PEKPSTLQRPQETVIRELQPQQ-QPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
E+ S + E + L+ + + R + + +++E D ++ A+
Sbjct: 1774 AEEES--RSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEA 1831
Query: 1522 KLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKR-LQESKQKDEDDE 1580
+ +++ + ++ E + E++RLR+L + FQ+R L+E + + D
Sbjct: 1832 ERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADI 1891
Query: 1581 EEE--------DDDVDTM--LIMQRLEAERRARTAMPAISVL------------------ 1612
EE D +++ L+ L R+ + A+
Sbjct: 1892 EERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRI 1951
Query: 1613 -----DLLQDEERR-----RQQQL---EEMRKREAEDRARQ----EEERRRQ------EE 1649
D L+ +E+ RQ+QL EE R+REAE+R ++ EEE RQ E
Sbjct: 1952 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2011
Query: 1650 ERTKRDAEEKRRQEEGYYSRLEAERRRQ---HDEAARRLLEPE 1689
ER K EE RR E R E E RQ EAA++ L+ E
Sbjct: 2012 ERLKAKVEEARRLRE----RAEQESARQLQLAQEAAQKRLQAE 2050
Score = 50.4 bits (119), Expect = 2e-05
Identities = 76/291 (26%), Positives = 121/291 (41%), Gaps = 36/291 (12%)
Query: 1403 VAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMK 1462
+A AE K++E + + + EE+ R+R E++L + R + TAQQ
Sbjct: 1657 LAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR-------QLAEGTAQQRL 1709
Query: 1463 PEKPSTLQRPQETVIRELQPQQQPRTIER--RDLQYITVSKEELSSGDSLSPDPWKRDAK 1520
+ ++ ET E Q Q + R R+ T ++EL + + +
Sbjct: 1710 AAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLA 1769
Query: 1521 EKLEKQQQMHIVDMLSKEIQELQSKPDRS-AEESDRLRKLMLEWQFQKRLQESKQKDEDD 1579
K +++ SK+ E ++ R AEE+ RLR L E + Q++L E ED
Sbjct: 1770 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE-----ED- 1823
Query: 1580 EEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEER---RRQQQLEEMRKREAED 1636
QR EAER + AI L+ E + ++ E +R AED
Sbjct: 1824 -----------AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1872
Query: 1637 RARQEEERRRQEEE--RTKRDAEEKRRQ-EEGYYSRLEAERRRQHDEAARR 1684
A Q RRR EE+ + K D EE+ Q + S LE ++ D +R
Sbjct: 1873 EAFQ---RRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1920
Score = 50.1 bits (118), Expect = 2e-05
Identities = 86/319 (26%), Positives = 133/319 (41%), Gaps = 41/319 (12%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
QV +RKR+ + KA E RE++R Q L ++R Q A + +Q
Sbjct: 1502 QVQDESQRKRQAEVELASRVKAEAEAAREKQRALQA--LEELRLQ----AEEAERRLRQA 1555
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
+ E+ +Q ET R + + Q + R T E + ++ + +A+
Sbjct: 1556 EVERARQVQVALETAQRSAEAELQSK---RASFAEKTAQLERSLQEEHVAVAQLREEAER 1612
Query: 1522 KLEKQQQMHIV-DMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQES---KQKDE 1577
+ ++Q + + +E++ Q K A E+ RLR E QK L ++ KQK+E
Sbjct: 1613 RAQQQAEAERAREEAERELERWQLK----ANEALRLRLQAEEVAQQKSLAQAEAEKQKEE 1668
Query: 1578 DDEE-------EEDDDVDTMLIMQRLEAERR-----ARTAMPAISVLDLLQDE----ERR 1621
+ E EE L Q LE +R+ A+ + A L L+ E E++
Sbjct: 1669 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1728
Query: 1622 RQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAE------EKRRQEEGYYSRLEAERR 1675
RQ LEE R + A ++R+ E E K AE K R EE S E ++
Sbjct: 1729 RQL-LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQ 1787
Query: 1676 RQHDEAAR-RLLEPEAPGL 1693
R EA R R L EA L
Sbjct: 1788 RLEAEAGRFRELAEEAARL 1806
Score = 49.7 bits (117), Expect = 3e-05
Identities = 62/289 (21%), Positives = 123/289 (42%), Gaps = 55/289 (19%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
Q+AA E R+R E + +K A EEE R+R+ ++ +++ + + ++
Sbjct: 1974 QLAAEEERRRREAEERVQKSLAA-EEEAARQRKAALEEVERLKAK----VEEARRLRERA 2028
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
+ E LQ QE + LQ +++ V ++E +L
Sbjct: 2029 EQESARQLQLAQEAAQKRLQAEEKAHAF--------AVQQKEQELQQTL----------- 2069
Query: 1522 KLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEE 1581
QQ+ ++D L E + + R+AEE++ R Q ++ +S+++ E+ E
Sbjct: 2070 ----QQEQSVLDQLRGEAEAAR----RAAEEAEEARV-----QAEREAAQSRRQVEEAER 2116
Query: 1582 EEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQE 1641
+ Q E + +AR A + E+ R++ + E R+ +AE A ++
Sbjct: 2117 ----------LKQSAEEQAQARAQAQAAA-------EKLRKEAEQEAARRAQAEQAALRQ 2159
Query: 1642 EERRRQEEERTKRDAEEKRRQEEGYYSRLEAER-RRQHDEAARRLLEPE 1689
++ E E+ K+ AE+ RQ+ L R + + + + LL+ E
Sbjct: 2160 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2208
Score = 48.9 bits (115), Expect = 4e-05
Identities = 74/326 (22%), Positives = 129/326 (39%), Gaps = 58/326 (17%)
Query: 1393 ANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEE------------------------- 1427
A Q L Q A AE K ++ ++KA++E+
Sbjct: 2152 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2211
Query: 1428 ------ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQ 1481
E R+R + E +L +R Q S L A +++ E + + R ++ R LQ
Sbjct: 2212 LKAEATEAARQRSQVEEELFSVRVQM---EELSKLKA-RIEAENRALILRDKDNTQRFLQ 2267
Query: 1482 PQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQE 1541
+ + + ++V+ +E + L A+E L +Q+ + ML +++Q
Sbjct: 2268 EEAEKMKQVAEEAARLSVAAQEAARLRQL--------AEEDLAQQRAL-AEKMLKEKMQA 2318
Query: 1542 LQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERR 1601
+Q AE ++ L + +RLQE K++ EE T + LEAER+
Sbjct: 2319 VQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEE-----TQGFQRTLEAERQ 2373
Query: 1602 ARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRR 1661
+ M A E R + ++ EM + +A + R++ EE K E
Sbjct: 2374 RQLEMSA---------EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELAT 2424
Query: 1662 QEEGYYSRLEAERRRQHDEAARRLLE 1687
QE+ + +R+Q D A RL E
Sbjct: 2425 QEKVTLVQTLEIQRQQSDHDAERLRE 2450
Score = 48.5 bits (114), Expect = 6e-05
Identities = 70/285 (24%), Positives = 122/285 (42%), Gaps = 37/285 (12%)
Query: 1419 EKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIR 1478
E +K + +EE ER RR+ + + + R + A A+ + EK LQ +E ++
Sbjct: 1486 EAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAR-EKQRALQALEELRLQ 1544
Query: 1479 ELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEK---LEKQ-QQMHI-VD 1533
+ +++ R E + + V+ E + EK LE+ Q+ H+ V
Sbjct: 1545 AEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVA 1604
Query: 1534 MLSKEIQ---ELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTM 1590
L +E + + Q++ +R+ EE++R + WQ + + ++ ++
Sbjct: 1605 QLREEAERRAQQQAEAERAREEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAE 1661
Query: 1591 LIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEE 1650
Q+ EAER AR RR + + + +R+RE A QE E++RQ E
Sbjct: 1662 AEKQKEEAEREAR----------------RRGKAEEQAVRQREL---AEQELEKQRQLAE 1702
Query: 1651 RTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEAPGLCR 1695
T ++R E RL AE + E R+LLE E L R
Sbjct: 1703 GT----AQQRLAAEQELIRLRAE--TEQGEQQRQLLEEELARLQR 1741
Score = 47.4 bits (111), Expect = 1e-04
Identities = 63/292 (21%), Positives = 113/292 (38%), Gaps = 46/292 (15%)
Query: 1422 KARLEEERERKRREQERKLGQMR-----TQSLNPAPFSPLTAQQMKPEKPSTLQRPQETV 1476
KAR E ER R E ++ +R T+ L A + + E+ +R +
Sbjct: 1436 KARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEE 1495
Query: 1477 IRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLS 1536
L+ Q Q + +R + S+ K +A+ EKQ+ + ++ L
Sbjct: 1496 AERLRRQVQDESQRKRQAEVELASRV-------------KAEAEAAREKQRALQALEELR 1542
Query: 1537 KEIQELQSKPDRSAEESDRLRKLMLEW---------------------QFQKRLQESKQK 1575
+ +E + + ++ E R ++ LE Q ++ LQE
Sbjct: 1543 LQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVA 1602
Query: 1576 DEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAE 1635
EE + Q+ EAER A + L +E R + Q EE+ ++++
Sbjct: 1603 VAQLREEAERRAQ-----QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSL 1657
Query: 1636 DRARQEEERRRQEEERTKRDAEEKR--RQEEGYYSRLEAERRRQHDEAARRL 1685
+A E+++ E E +R E++ RQ E LE +R+ A +RL
Sbjct: 1658 AQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1709
Score = 47.0 bits (110), Expect = 2e-04
Identities = 68/323 (21%), Positives = 132/323 (40%), Gaps = 70/323 (21%)
Query: 1404 AAAERRKREEHQRWYEKEKARLEEERE----RKRREQERKLGQMRTQSLNPAPFSPLTAQ 1459
A A RR EE E+AR++ ERE R++ E+ +L Q + + A+
Sbjct: 2083 AEAARRAAEE------AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2136
Query: 1460 QMKPEKPSTLQR---PQETVIRELQP----QQQPRTIERRDLQYITVSKEELSSGDSLSP 1512
+++ E R ++ +R+ Q ++ + + L+ ++EL++
Sbjct: 2137 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTT------ 2190
Query: 1513 DPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQES 1572
+L+ ++ H ++L +E+Q L+++ A E+ R R + E F R+Q
Sbjct: 2191 --------LRLQLEETDHQKNLLDEELQRLKAE----ATEAARQRSQVEEELFSVRVQME 2238
Query: 1573 KQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEE---- 1628
+ + R+EAE RA + LQ+E + +Q EE
Sbjct: 2239 ELSK---------------LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARL 2283
Query: 1629 ---------MRKREAEDRARQE-------EERRRQEEERTKRDAEEKRRQEEGYYSRLEA 1672
+R+ ED A+Q +E+ + +E T+ AE + Q++ ++ +A
Sbjct: 2284 SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQA 2343
Query: 1673 ERRRQHDEAARRLLEPEAPGLCR 1695
R ++ E + L E G R
Sbjct: 2344 RRLQEDKEQMAQQLAEETQGFQR 2366
Score = 43.9 bits (102), Expect = 0.001
Identities = 71/291 (24%), Positives = 127/291 (43%), Gaps = 29/291 (9%)
Query: 1413 EHQR-WYEKEKARLEEERE---RKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPST 1468
+HQ+ ++E RL+ E R+R + E +L +R Q S L A+ ++ E +
Sbjct: 2199 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQM---EELSKLKAR-IEAENRAL 2254
Query: 1469 LQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQ 1528
+ R ++ R LQ + + + ++V+ +E + L A+E L +Q+
Sbjct: 2255 ILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQL--------AEEDLAQQRA 2306
Query: 1529 MHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVD 1588
+ ML +++Q +Q AE ++ L + +RLQE K++ EE
Sbjct: 2307 L-AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQ 2365
Query: 1589 TMLIMQR-------LEAER-RARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQ 1640
L +R EAER + R A + + +D +R R+Q E K + A Q
Sbjct: 2366 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2425
Query: 1641 EEERRRQ--EEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
E+ Q E +R + D + +R +E + LE E+ + EA L+ E
Sbjct: 2426 EKVTLVQTLEIQRQQSDHDAERLREA--IAELEREKEKLQQEAKLLQLKSE 2474
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 67.8 bits (164), Expect = 9e-11
Identities = 74/316 (23%), Positives = 147/316 (46%), Gaps = 53/316 (16%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
Q A AE+ +E+ Q E + + E E +Q+++L Q + + L Q+
Sbjct: 2308 QRALAEKMLKEKMQAVQEATRLKAEAEL----LQQQKELAQEQARRL----------QED 2353
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
K + L + R L+ ++Q + + + + + E+S + + + +R K+
Sbjct: 2354 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2413
Query: 1522 KLEKQQQMHIVDMLSKE----IQELQSKPDRSAEESDRLRKLM--LEWQFQKRLQESKQK 1575
E +++H ++ ++E +Q L+ + +S +++RLR+ + LE + +K QE+K
Sbjct: 2414 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2473
Query: 1576 DEDDEEEED------------------DDVDTMLIMQRLEAERRARTAM---PAISVLDL 1614
EE + + D++L +R + +A+ ++
Sbjct: 2474 QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ 2533
Query: 1615 LQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAER 1674
L++E++R+QQQ+E+ R+R A EE RRRQ E AEE R+++ +LE +R
Sbjct: 2534 LREEQQRQQQQMEQERQRLV---ASMEEARRRQHE------AEEGVRRKQEELQQLEQQR 2584
Query: 1675 RRQHD---EAARRLLE 1687
R+Q + E +RL E
Sbjct: 2585 RQQEELLAEENQRLRE 2600
Score = 65.1 bits (157), Expect = 6e-10
Identities = 77/315 (24%), Positives = 134/315 (42%), Gaps = 36/315 (11%)
Query: 1401 AQVAAAERRKREEHQRWYEKEKA----RLEEERERKRREQERKLGQMRTQSLNPAPFSPL 1456
A++A E+ E R +++A RLEE+ + + + E +L Q+R S S L
Sbjct: 1856 AEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKAS-----DSEL 1910
Query: 1457 TAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK 1516
Q+ E +R E I L+ + + +L+ EL S + D +
Sbjct: 1911 ERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELEL------ELGRIRSNAEDTLR 1964
Query: 1517 RDAKEKLEKQQQMHIV---DMLSKEIQELQSKPDRSAEESDRLRKLMLEW--QFQKRLQE 1571
+ +LE +Q + + +E +E K + EE+ R RK LE + + +++E
Sbjct: 1965 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2024
Query: 1572 SKQKDEDDEEEEDDDVDTM--LIMQRLEAERRA-------------RTAMPAISVLDLLQ 1616
+++ E E+E + +RL+AE +A +T SVLD L+
Sbjct: 2025 ARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR 2084
Query: 1617 DEERRRQQQLEEMRKREAEDRARQEEERRRQEE-ERTKRDAEEKRRQEEGYYSRLEAERR 1675
E ++ EE + + + RR+ EE ER K+ AEE+ + + E R+
Sbjct: 2085 GEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK 2144
Query: 1676 RQHDEAARRLLEPEA 1690
EAARR +A
Sbjct: 2145 EAEQEAARRAQAEQA 2159
Score = 63.9 bits (154), Expect = 1e-09
Identities = 79/314 (25%), Positives = 139/314 (44%), Gaps = 41/314 (13%)
Query: 1395 QIGLPSAQVAAAERRKREEHQRWYEKEKARLEE---ERERKRREQERKLGQMRTQSLNPA 1451
Q+ AQ A R+ +E Q+ ++E R EE + ++++R + +L Q+R S
Sbjct: 1378 QLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1437
Query: 1452 PFSPLTAQQMKPEKPSTLQRPQET-VIR-ELQPQQQPRTIERRDLQYITVSKEELSSGDS 1509
A+Q + + S L+ +E V+R +L+ ++ R +LQ + EE +
Sbjct: 1438 QAK---ARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQ-- 1492
Query: 1510 LSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQ---ELQSKPDRSAE---ESDRLRKLMLEW 1563
KR A+E+ E+ ++ + D ++ Q EL S+ AE E R + + E
Sbjct: 1493 ------KRQAQEEAERLRRQ-VQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1545
Query: 1564 QFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPA--------------I 1609
+ Q E + + + E V + EAE +++ A A +
Sbjct: 1546 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1605
Query: 1610 SVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSR 1669
+V L ++ ERR QQQ E R RE +R + + + E R + AEE +Q+ S
Sbjct: 1606 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQK----SL 1661
Query: 1670 LEAERRRQHDEAAR 1683
+AE +Q +EA R
Sbjct: 1662 AQAEAEKQKEEAER 1675
Score = 57.4 bits (137), Expect = 1e-07
Identities = 83/341 (24%), Positives = 138/341 (40%), Gaps = 77/341 (22%)
Query: 1409 RKREEHQRWYEKEKARLEEERERKRR-----EQERKLGQMRTQSLNPAPFSPLTAQQMKP 1463
R+ EE +R E+++A EERER E++R+L + Q+ Q +
Sbjct: 1346 RRMEEEERLAEQQRA---EERERLAEVEAALEKQRQLAEAHAQA----------KAQAER 1392
Query: 1464 EKPSTLQRPQETVIRE----LQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDA 1519
E QR QE V+R + QQQ R+I+ +LQ + S E + + +R
Sbjct: 1393 EAKELQQRMQEEVVRREEAAVDAQQQKRSIQE-ELQQLRQSSEAEIQAKARQAEAAERS- 1450
Query: 1520 KEKLEKQQQMHIVDM------------------LSKEIQELQSKPDRSAEESDRLRKLML 1561
+L ++++ +V + L +E +++ ++ EE++RLR+ +
Sbjct: 1451 --RLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1508
Query: 1562 EWQFQKRLQE----SKQKDEDDEEEEDDDVDTMLIMQRL---EAERRARTAMP--AISVL 1612
+ +KR E S+ K E + E L RL EAERR R A A V
Sbjct: 1509 DESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQ 1568
Query: 1613 DLLQDEERRRQQQLEEMR------------------------KREAEDRARQEEERRRQE 1648
L+ +R + +L+ R + EAE RA+Q+ E R
Sbjct: 1569 VALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAR 1628
Query: 1649 EERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
EE + + + E RL+AE Q A+ E +
Sbjct: 1629 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQ 1669
Score = 54.3 bits (129), Expect = 1e-06
Identities = 67/278 (24%), Positives = 118/278 (42%), Gaps = 51/278 (18%)
Query: 1406 AERRKREEHQRWYEKEKARLEE-ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPE 1464
AER+++ E E+ K R+ E R + R E++ + + + + + A Q K
Sbjct: 2374 AERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT 2433
Query: 1465 KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLE 1524
TL E+Q QQ ER + +E+ + +++AK
Sbjct: 2434 LVQTL---------EIQRQQSDHDAERLREAIAELEREK---------EKLQQEAKLLQL 2475
Query: 1525 KQQQMHIVDMLSKEIQELQSKPDRSAEESDRL---------RKLMLEWQFQKRLQESKQK 1575
K ++M V + +QE Q+ E D L K LE FQ + +++Q
Sbjct: 2476 KSEEMQTVQQ-EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL 2534
Query: 1576 DEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAE 1635
E+ + ++ Q++E ER+ A +E RRRQ + EE +R+ E
Sbjct: 2535 REEQQRQQ----------QQMEQERQRLVAS---------MEEARRRQHEAEEGVRRKQE 2575
Query: 1636 DRARQEEERRRQEE---ERTKRDAEEKRRQEEGYYSRL 1670
+ + E++RR+QEE E +R E+ + EE + + L
Sbjct: 2576 ELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2613
Score = 53.1 bits (126), Expect = 2e-06
Identities = 82/330 (24%), Positives = 141/330 (42%), Gaps = 47/330 (14%)
Query: 1398 LPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLT 1457
+P A A + R+E E E R E+ E +R ++ + ++ L +
Sbjct: 1240 MPLADSQAVREQLRQEQALLEEIE--RHGEKVEECQRFAKQYINAIKDYELQLVTYKAQL 1297
Query: 1458 AQQMKPEKPSTLQRPQETVIRELQPQQ----QPRTIERRDLQYITVSKEELSSGDSLSPD 1513
P K +Q E+VI+E + + T+ + +++I+ + + + L+ +
Sbjct: 1298 EPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLA-E 1356
Query: 1514 PWKRDAKEKL-------EKQQQMHIVDMLSKEIQELQSKP--DRSAEESDRLRKLMLEWQ 1564
+ + +E+L EKQ+Q+ +K E ++K R EE R + ++ Q
Sbjct: 1357 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQ 1416
Query: 1565 FQKR-LQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQ 1623
QKR +QE Q+ E E ++ EA R+R + + LQ E RQ
Sbjct: 1417 QQKRSIQEELQQLRQSSEAE-----IQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQ 1471
Query: 1624 Q-----QLEEMRKR----EAEDRARQEE----ERRRQEEERTKRDAE-----------EK 1659
+ +L+ +R R EA+ R QEE R+ Q+E + KR AE E
Sbjct: 1472 RGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1531
Query: 1660 RRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
R+++ LE E R Q +EA RRL + E
Sbjct: 1532 AREKQRALQALE-ELRLQAEEAERRLRQAE 1560
Score = 52.8 bits (125), Expect = 3e-06
Identities = 84/343 (24%), Positives = 145/343 (42%), Gaps = 71/343 (20%)
Query: 1406 AERRKREEHQRWYEKEKARLEEERE---RKRREQERKLGQMRTQSLNPAPFSPLTAQQMK 1462
AE + E+ ++ E+E ARL+ E +KR+E E +L ++R A L A + +
Sbjct: 1724 AETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR------AEMEVLLASKAR 1777
Query: 1463 PEKPSTLQRPQETVIRELQPQQ-QPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
E+ S + E + L+ + + R + + +++E D ++ A+
Sbjct: 1778 AEEES--RSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEA 1835
Query: 1522 KLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKR-LQESKQKDEDDE 1580
+ +++ + ++ E + E++RLR+L + FQ+R L+E + + D
Sbjct: 1836 ERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADI 1895
Query: 1581 EEE--------DDDVDTM--LIMQRLEAERRARTAMPAISVL------------------ 1612
EE D +++ L+ L R+ + A+
Sbjct: 1896 EERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRI 1955
Query: 1613 -----DLLQDEERR-----RQQQL---EEMRKREAEDRARQ----EEERRRQ------EE 1649
D L+ +E+ RQ+QL EE R+REAE+R ++ EEE RQ E
Sbjct: 1956 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2015
Query: 1650 ERTKRDAEEKRRQEEGYYSRLEAERRRQ---HDEAARRLLEPE 1689
ER K EE RR E R E E RQ EAA++ L+ E
Sbjct: 2016 ERLKAKVEEARRLRE----RAEQESARQLQLAQEAAQKRLQAE 2054
Score = 50.4 bits (119), Expect = 2e-05
Identities = 76/291 (26%), Positives = 121/291 (41%), Gaps = 36/291 (12%)
Query: 1403 VAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMK 1462
+A AE K++E + + + EE+ R+R E++L + R + TAQQ
Sbjct: 1661 LAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR-------QLAEGTAQQRL 1713
Query: 1463 PEKPSTLQRPQETVIRELQPQQQPRTIER--RDLQYITVSKEELSSGDSLSPDPWKRDAK 1520
+ ++ ET E Q Q + R R+ T ++EL + + +
Sbjct: 1714 AAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLA 1773
Query: 1521 EKLEKQQQMHIVDMLSKEIQELQSKPDRS-AEESDRLRKLMLEWQFQKRLQESKQKDEDD 1579
K +++ SK+ E ++ R AEE+ RLR L E + Q++L E ED
Sbjct: 1774 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE-----ED- 1827
Query: 1580 EEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEER---RRQQQLEEMRKREAED 1636
QR EAER + AI L+ E + ++ E +R AED
Sbjct: 1828 -----------AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1876
Query: 1637 RARQEEERRRQEEE--RTKRDAEEKRRQ-EEGYYSRLEAERRRQHDEAARR 1684
A Q RRR EE+ + K D EE+ Q + S LE ++ D +R
Sbjct: 1877 EAFQ---RRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1924
Score = 50.1 bits (118), Expect = 2e-05
Identities = 86/319 (26%), Positives = 133/319 (41%), Gaps = 41/319 (12%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
QV +RKR+ + KA E RE++R Q L ++R Q A + +Q
Sbjct: 1506 QVQDESQRKRQAEVELASRVKAEAEAAREKQRALQA--LEELRLQ----AEEAERRLRQA 1559
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
+ E+ +Q ET R + + Q + R T E + ++ + +A+
Sbjct: 1560 EVERARQVQVALETAQRSAEAELQSK---RASFAEKTAQLERSLQEEHVAVAQLREEAER 1616
Query: 1522 KLEKQQQMHIV-DMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQES---KQKDE 1577
+ ++Q + + +E++ Q K A E+ RLR E QK L ++ KQK+E
Sbjct: 1617 RAQQQAEAERAREEAERELERWQLK----ANEALRLRLQAEEVAQQKSLAQAEAEKQKEE 1672
Query: 1578 DDEE-------EEDDDVDTMLIMQRLEAERR-----ARTAMPAISVLDLLQDE----ERR 1621
+ E EE L Q LE +R+ A+ + A L L+ E E++
Sbjct: 1673 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1732
Query: 1622 RQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAE------EKRRQEEGYYSRLEAERR 1675
RQ LEE R + A ++R+ E E K AE K R EE S E ++
Sbjct: 1733 RQL-LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQ 1791
Query: 1676 RQHDEAAR-RLLEPEAPGL 1693
R EA R R L EA L
Sbjct: 1792 RLEAEAGRFRELAEEAARL 1810
Score = 49.7 bits (117), Expect = 3e-05
Identities = 62/289 (21%), Positives = 123/289 (42%), Gaps = 55/289 (19%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
Q+AA E R+R E + +K A EEE R+R+ ++ +++ + + ++
Sbjct: 1978 QLAAEEERRRREAEERVQKSLAA-EEEAARQRKAALEEVERLKAK----VEEARRLRERA 2032
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
+ E LQ QE + LQ +++ V ++E +L
Sbjct: 2033 EQESARQLQLAQEAAQKRLQAEEKAHAF--------AVQQKEQELQQTL----------- 2073
Query: 1522 KLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEE 1581
QQ+ ++D L E + + R+AEE++ R Q ++ +S+++ E+ E
Sbjct: 2074 ----QQEQSVLDQLRGEAEAAR----RAAEEAEEARV-----QAEREAAQSRRQVEEAER 2120
Query: 1582 EEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQE 1641
+ Q E + +AR A + E+ R++ + E R+ +AE A ++
Sbjct: 2121 ----------LKQSAEEQAQARAQAQAAA-------EKLRKEAEQEAARRAQAEQAALRQ 2163
Query: 1642 EERRRQEEERTKRDAEEKRRQEEGYYSRLEAER-RRQHDEAARRLLEPE 1689
++ E E+ K+ AE+ RQ+ L R + + + + LL+ E
Sbjct: 2164 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2212
Score = 48.9 bits (115), Expect = 4e-05
Identities = 74/326 (22%), Positives = 129/326 (39%), Gaps = 58/326 (17%)
Query: 1393 ANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEE------------------------- 1427
A Q L Q A AE K ++ ++KA++E+
Sbjct: 2156 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2215
Query: 1428 ------ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQ 1481
E R+R + E +L +R Q S L A +++ E + + R ++ R LQ
Sbjct: 2216 LKAEATEAARQRSQVEEELFSVRVQM---EELSKLKA-RIEAENRALILRDKDNTQRFLQ 2271
Query: 1482 PQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQE 1541
+ + + ++V+ +E + L A+E L +Q+ + ML +++Q
Sbjct: 2272 EEAEKMKQVAEEAARLSVAAQEAARLRQL--------AEEDLAQQRAL-AEKMLKEKMQA 2322
Query: 1542 LQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERR 1601
+Q AE ++ L + +RLQE K++ EE T + LEAER+
Sbjct: 2323 VQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEE-----TQGFQRTLEAERQ 2377
Query: 1602 ARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRR 1661
+ M A E R + ++ EM + +A + R++ EE K E
Sbjct: 2378 RQLEMSA---------EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELAT 2428
Query: 1662 QEEGYYSRLEAERRRQHDEAARRLLE 1687
QE+ + +R+Q D A RL E
Sbjct: 2429 QEKVTLVQTLEIQRQQSDHDAERLRE 2454
Score = 48.5 bits (114), Expect = 6e-05
Identities = 70/285 (24%), Positives = 122/285 (42%), Gaps = 37/285 (12%)
Query: 1419 EKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIR 1478
E +K + +EE ER RR+ + + + R + A A+ + EK LQ +E ++
Sbjct: 1490 EAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAR-EKQRALQALEELRLQ 1548
Query: 1479 ELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEK---LEKQ-QQMHI-VD 1533
+ +++ R E + + V+ E + EK LE+ Q+ H+ V
Sbjct: 1549 AEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVA 1608
Query: 1534 MLSKEIQ---ELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTM 1590
L +E + + Q++ +R+ EE++R + WQ + + ++ ++
Sbjct: 1609 QLREEAERRAQQQAEAERAREEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAE 1665
Query: 1591 LIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEE 1650
Q+ EAER AR RR + + + +R+RE A QE E++RQ E
Sbjct: 1666 AEKQKEEAEREAR----------------RRGKAEEQAVRQREL---AEQELEKQRQLAE 1706
Query: 1651 RTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEAPGLCR 1695
T ++R E RL AE + E R+LLE E L R
Sbjct: 1707 GT----AQQRLAAEQELIRLRAE--TEQGEQQRQLLEEELARLQR 1745
Score = 47.4 bits (111), Expect = 1e-04
Identities = 63/292 (21%), Positives = 113/292 (38%), Gaps = 46/292 (15%)
Query: 1422 KARLEEERERKRREQERKLGQMR-----TQSLNPAPFSPLTAQQMKPEKPSTLQRPQETV 1476
KAR E ER R E ++ +R T+ L A + + E+ +R +
Sbjct: 1440 KARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEE 1499
Query: 1477 IRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLS 1536
L+ Q Q + +R + S+ K +A+ EKQ+ + ++ L
Sbjct: 1500 AERLRRQVQDESQRKRQAEVELASRV-------------KAEAEAAREKQRALQALEELR 1546
Query: 1537 KEIQELQSKPDRSAEESDRLRKLMLEW---------------------QFQKRLQESKQK 1575
+ +E + + ++ E R ++ LE Q ++ LQE
Sbjct: 1547 LQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVA 1606
Query: 1576 DEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAE 1635
EE + Q+ EAER A + L +E R + Q EE+ ++++
Sbjct: 1607 VAQLREEAERRAQ-----QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSL 1661
Query: 1636 DRARQEEERRRQEEERTKRDAEEKR--RQEEGYYSRLEAERRRQHDEAARRL 1685
+A E+++ E E +R E++ RQ E LE +R+ A +RL
Sbjct: 1662 AQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1713
Score = 47.0 bits (110), Expect = 2e-04
Identities = 68/323 (21%), Positives = 132/323 (40%), Gaps = 70/323 (21%)
Query: 1404 AAAERRKREEHQRWYEKEKARLEEERE----RKRREQERKLGQMRTQSLNPAPFSPLTAQ 1459
A A RR EE E+AR++ ERE R++ E+ +L Q + + A+
Sbjct: 2087 AEAARRAAEE------AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2140
Query: 1460 QMKPEKPSTLQR---PQETVIRELQP----QQQPRTIERRDLQYITVSKEELSSGDSLSP 1512
+++ E R ++ +R+ Q ++ + + L+ ++EL++
Sbjct: 2141 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTT------ 2194
Query: 1513 DPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQES 1572
+L+ ++ H ++L +E+Q L+++ A E+ R R + E F R+Q
Sbjct: 2195 --------LRLQLEETDHQKNLLDEELQRLKAE----ATEAARQRSQVEEELFSVRVQME 2242
Query: 1573 KQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEE---- 1628
+ + R+EAE RA + LQ+E + +Q EE
Sbjct: 2243 ELSK---------------LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARL 2287
Query: 1629 ---------MRKREAEDRARQE-------EERRRQEEERTKRDAEEKRRQEEGYYSRLEA 1672
+R+ ED A+Q +E+ + +E T+ AE + Q++ ++ +A
Sbjct: 2288 SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQA 2347
Query: 1673 ERRRQHDEAARRLLEPEAPGLCR 1695
R ++ E + L E G R
Sbjct: 2348 RRLQEDKEQMAQQLAEETQGFQR 2370
Score = 43.9 bits (102), Expect = 0.001
Identities = 71/291 (24%), Positives = 127/291 (43%), Gaps = 29/291 (9%)
Query: 1413 EHQR-WYEKEKARLEEERE---RKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPST 1468
+HQ+ ++E RL+ E R+R + E +L +R Q S L A+ ++ E +
Sbjct: 2203 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQM---EELSKLKAR-IEAENRAL 2258
Query: 1469 LQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQ 1528
+ R ++ R LQ + + + ++V+ +E + L A+E L +Q+
Sbjct: 2259 ILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQL--------AEEDLAQQRA 2310
Query: 1529 MHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVD 1588
+ ML +++Q +Q AE ++ L + +RLQE K++ EE
Sbjct: 2311 L-AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQ 2369
Query: 1589 TMLIMQR-------LEAER-RARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQ 1640
L +R EAER + R A + + +D +R R+Q E K + A Q
Sbjct: 2370 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2429
Query: 1641 EEERRRQ--EEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
E+ Q E +R + D + +R +E + LE E+ + EA L+ E
Sbjct: 2430 EKVTLVQTLEIQRQQSDHDAERLREA--IAELEREKEKLQQEAKLLQLKSE 2478
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 67.8 bits (164), Expect = 9e-11
Identities = 74/316 (23%), Positives = 147/316 (46%), Gaps = 53/316 (16%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
Q A AE+ +E+ Q E + + E E +Q+++L Q + + L Q+
Sbjct: 2304 QRALAEKMLKEKMQAVQEATRLKAEAEL----LQQQKELAQEQARRL----------QED 2349
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
K + L + R L+ ++Q + + + + + E+S + + + +R K+
Sbjct: 2350 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2409
Query: 1522 KLEKQQQMHIVDMLSKE----IQELQSKPDRSAEESDRLRKLM--LEWQFQKRLQESKQK 1575
E +++H ++ ++E +Q L+ + +S +++RLR+ + LE + +K QE+K
Sbjct: 2410 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2469
Query: 1576 DEDDEEEED------------------DDVDTMLIMQRLEAERRARTAM---PAISVLDL 1614
EE + + D++L +R + +A+ ++
Sbjct: 2470 QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ 2529
Query: 1615 LQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAER 1674
L++E++R+QQQ+E+ R+R A EE RRRQ E AEE R+++ +LE +R
Sbjct: 2530 LREEQQRQQQQMEQERQRLV---ASMEEARRRQHE------AEEGVRRKQEELQQLEQQR 2580
Query: 1675 RRQHD---EAARRLLE 1687
R+Q + E +RL E
Sbjct: 2581 RQQEELLAEENQRLRE 2596
Score = 65.1 bits (157), Expect = 6e-10
Identities = 77/315 (24%), Positives = 134/315 (42%), Gaps = 36/315 (11%)
Query: 1401 AQVAAAERRKREEHQRWYEKEKA----RLEEERERKRREQERKLGQMRTQSLNPAPFSPL 1456
A++A E+ E R +++A RLEE+ + + + E +L Q+R S S L
Sbjct: 1852 AEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKAS-----DSEL 1906
Query: 1457 TAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK 1516
Q+ E +R E I L+ + + +L+ EL S + D +
Sbjct: 1907 ERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELEL------ELGRIRSNAEDTLR 1960
Query: 1517 RDAKEKLEKQQQMHIV---DMLSKEIQELQSKPDRSAEESDRLRKLMLEW--QFQKRLQE 1571
+ +LE +Q + + +E +E K + EE+ R RK LE + + +++E
Sbjct: 1961 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2020
Query: 1572 SKQKDEDDEEEEDDDVDTM--LIMQRLEAERRA-------------RTAMPAISVLDLLQ 1616
+++ E E+E + +RL+AE +A +T SVLD L+
Sbjct: 2021 ARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR 2080
Query: 1617 DEERRRQQQLEEMRKREAEDRARQEEERRRQEE-ERTKRDAEEKRRQEEGYYSRLEAERR 1675
E ++ EE + + + RR+ EE ER K+ AEE+ + + E R+
Sbjct: 2081 GEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK 2140
Query: 1676 RQHDEAARRLLEPEA 1690
EAARR +A
Sbjct: 2141 EAEQEAARRAQAEQA 2155
Score = 63.9 bits (154), Expect = 1e-09
Identities = 79/314 (25%), Positives = 139/314 (44%), Gaps = 41/314 (13%)
Query: 1395 QIGLPSAQVAAAERRKREEHQRWYEKEKARLEE---ERERKRREQERKLGQMRTQSLNPA 1451
Q+ AQ A R+ +E Q+ ++E R EE + ++++R + +L Q+R S
Sbjct: 1374 QLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1433
Query: 1452 PFSPLTAQQMKPEKPSTLQRPQET-VIR-ELQPQQQPRTIERRDLQYITVSKEELSSGDS 1509
A+Q + + S L+ +E V+R +L+ ++ R +LQ + EE +
Sbjct: 1434 QAK---ARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQ-- 1488
Query: 1510 LSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQ---ELQSKPDRSAE---ESDRLRKLMLEW 1563
KR A+E+ E+ ++ + D ++ Q EL S+ AE E R + + E
Sbjct: 1489 ------KRQAQEEAERLRRQ-VQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1541
Query: 1564 QFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPA--------------I 1609
+ Q E + + + E V + EAE +++ A A +
Sbjct: 1542 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1601
Query: 1610 SVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSR 1669
+V L ++ ERR QQQ E R RE +R + + + E R + AEE +Q+ S
Sbjct: 1602 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQK----SL 1657
Query: 1670 LEAERRRQHDEAAR 1683
+AE +Q +EA R
Sbjct: 1658 AQAEAEKQKEEAER 1671
Score = 57.4 bits (137), Expect = 1e-07
Identities = 83/341 (24%), Positives = 138/341 (40%), Gaps = 77/341 (22%)
Query: 1409 RKREEHQRWYEKEKARLEEERERKRR-----EQERKLGQMRTQSLNPAPFSPLTAQQMKP 1463
R+ EE +R E+++A EERER E++R+L + Q+ Q +
Sbjct: 1342 RRMEEEERLAEQQRA---EERERLAEVEAALEKQRQLAEAHAQA----------KAQAER 1388
Query: 1464 EKPSTLQRPQETVIRE----LQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDA 1519
E QR QE V+R + QQQ R+I+ +LQ + S E + + +R
Sbjct: 1389 EAKELQQRMQEEVVRREEAAVDAQQQKRSIQE-ELQQLRQSSEAEIQAKARQAEAAERS- 1446
Query: 1520 KEKLEKQQQMHIVDM------------------LSKEIQELQSKPDRSAEESDRLRKLML 1561
+L ++++ +V + L +E +++ ++ EE++RLR+ +
Sbjct: 1447 --RLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1504
Query: 1562 EWQFQKRLQE----SKQKDEDDEEEEDDDVDTMLIMQRL---EAERRARTAMP--AISVL 1612
+ +KR E S+ K E + E L RL EAERR R A A V
Sbjct: 1505 DESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQ 1564
Query: 1613 DLLQDEERRRQQQLEEMR------------------------KREAEDRARQEEERRRQE 1648
L+ +R + +L+ R + EAE RA+Q+ E R
Sbjct: 1565 VALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAR 1624
Query: 1649 EERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
EE + + + E RL+AE Q A+ E +
Sbjct: 1625 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQ 1665
Score = 54.3 bits (129), Expect = 1e-06
Identities = 67/278 (24%), Positives = 118/278 (42%), Gaps = 51/278 (18%)
Query: 1406 AERRKREEHQRWYEKEKARLEE-ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPE 1464
AER+++ E E+ K R+ E R + R E++ + + + + + A Q K
Sbjct: 2370 AERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT 2429
Query: 1465 KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLE 1524
TL E+Q QQ ER + +E+ + +++AK
Sbjct: 2430 LVQTL---------EIQRQQSDHDAERLREAIAELEREK---------EKLQQEAKLLQL 2471
Query: 1525 KQQQMHIVDMLSKEIQELQSKPDRSAEESDRL---------RKLMLEWQFQKRLQESKQK 1575
K ++M V + +QE Q+ E D L K LE FQ + +++Q
Sbjct: 2472 KSEEMQTVQQ-EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL 2530
Query: 1576 DEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAE 1635
E+ + ++ Q++E ER+ A +E RRRQ + EE +R+ E
Sbjct: 2531 REEQQRQQ----------QQMEQERQRLVAS---------MEEARRRQHEAEEGVRRKQE 2571
Query: 1636 DRARQEEERRRQEE---ERTKRDAEEKRRQEEGYYSRL 1670
+ + E++RR+QEE E +R E+ + EE + + L
Sbjct: 2572 ELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2609
Score = 53.1 bits (126), Expect = 2e-06
Identities = 82/330 (24%), Positives = 141/330 (42%), Gaps = 47/330 (14%)
Query: 1398 LPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLT 1457
+P A A + R+E E E R E+ E +R ++ + ++ L +
Sbjct: 1236 MPLADSQAVREQLRQEQALLEEIE--RHGEKVEECQRFAKQYINAIKDYELQLVTYKAQL 1293
Query: 1458 AQQMKPEKPSTLQRPQETVIRELQPQQ----QPRTIERRDLQYITVSKEELSSGDSLSPD 1513
P K +Q E+VI+E + + T+ + +++I+ + + + L+ +
Sbjct: 1294 EPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLA-E 1352
Query: 1514 PWKRDAKEKL-------EKQQQMHIVDMLSKEIQELQSKP--DRSAEESDRLRKLMLEWQ 1564
+ + +E+L EKQ+Q+ +K E ++K R EE R + ++ Q
Sbjct: 1353 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQ 1412
Query: 1565 FQKR-LQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQ 1623
QKR +QE Q+ E E ++ EA R+R + + LQ E RQ
Sbjct: 1413 QQKRSIQEELQQLRQSSEAE-----IQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQ 1467
Query: 1624 Q-----QLEEMRKR----EAEDRARQEE----ERRRQEEERTKRDAE-----------EK 1659
+ +L+ +R R EA+ R QEE R+ Q+E + KR AE E
Sbjct: 1468 RGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1527
Query: 1660 RRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
R+++ LE E R Q +EA RRL + E
Sbjct: 1528 AREKQRALQALE-ELRLQAEEAERRLRQAE 1556
Score = 52.8 bits (125), Expect = 3e-06
Identities = 84/343 (24%), Positives = 145/343 (42%), Gaps = 71/343 (20%)
Query: 1406 AERRKREEHQRWYEKEKARLEEERE---RKRREQERKLGQMRTQSLNPAPFSPLTAQQMK 1462
AE + E+ ++ E+E ARL+ E +KR+E E +L ++R A L A + +
Sbjct: 1720 AETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR------AEMEVLLASKAR 1773
Query: 1463 PEKPSTLQRPQETVIRELQPQQ-QPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
E+ S + E + L+ + + R + + +++E D ++ A+
Sbjct: 1774 AEEES--RSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEA 1831
Query: 1522 KLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKR-LQESKQKDEDDE 1580
+ +++ + ++ E + E++RLR+L + FQ+R L+E + + D
Sbjct: 1832 ERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADI 1891
Query: 1581 EEE--------DDDVDTM--LIMQRLEAERRARTAMPAISVL------------------ 1612
EE D +++ L+ L R+ + A+
Sbjct: 1892 EERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRI 1951
Query: 1613 -----DLLQDEERR-----RQQQL---EEMRKREAEDRARQ----EEERRRQ------EE 1649
D L+ +E+ RQ+QL EE R+REAE+R ++ EEE RQ E
Sbjct: 1952 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2011
Query: 1650 ERTKRDAEEKRRQEEGYYSRLEAERRRQ---HDEAARRLLEPE 1689
ER K EE RR E R E E RQ EAA++ L+ E
Sbjct: 2012 ERLKAKVEEARRLRE----RAEQESARQLQLAQEAAQKRLQAE 2050
Score = 50.4 bits (119), Expect = 2e-05
Identities = 76/291 (26%), Positives = 121/291 (41%), Gaps = 36/291 (12%)
Query: 1403 VAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMK 1462
+A AE K++E + + + EE+ R+R E++L + R + TAQQ
Sbjct: 1657 LAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR-------QLAEGTAQQRL 1709
Query: 1463 PEKPSTLQRPQETVIRELQPQQQPRTIER--RDLQYITVSKEELSSGDSLSPDPWKRDAK 1520
+ ++ ET E Q Q + R R+ T ++EL + + +
Sbjct: 1710 AAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLA 1769
Query: 1521 EKLEKQQQMHIVDMLSKEIQELQSKPDRS-AEESDRLRKLMLEWQFQKRLQESKQKDEDD 1579
K +++ SK+ E ++ R AEE+ RLR L E + Q++L E ED
Sbjct: 1770 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE-----ED- 1823
Query: 1580 EEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEER---RRQQQLEEMRKREAED 1636
QR EAER + AI L+ E + ++ E +R AED
Sbjct: 1824 -----------AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1872
Query: 1637 RARQEEERRRQEEE--RTKRDAEEKRRQ-EEGYYSRLEAERRRQHDEAARR 1684
A Q RRR EE+ + K D EE+ Q + S LE ++ D +R
Sbjct: 1873 EAFQ---RRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1920
Score = 50.1 bits (118), Expect = 2e-05
Identities = 86/319 (26%), Positives = 133/319 (41%), Gaps = 41/319 (12%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
QV +RKR+ + KA E RE++R Q L ++R Q A + +Q
Sbjct: 1502 QVQDESQRKRQAEVELASRVKAEAEAAREKQRALQA--LEELRLQ----AEEAERRLRQA 1555
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
+ E+ +Q ET R + + Q + R T E + ++ + +A+
Sbjct: 1556 EVERARQVQVALETAQRSAEAELQSK---RASFAEKTAQLERSLQEEHVAVAQLREEAER 1612
Query: 1522 KLEKQQQMHIV-DMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQES---KQKDE 1577
+ ++Q + + +E++ Q K A E+ RLR E QK L ++ KQK+E
Sbjct: 1613 RAQQQAEAERAREEAERELERWQLK----ANEALRLRLQAEEVAQQKSLAQAEAEKQKEE 1668
Query: 1578 DDEE-------EEDDDVDTMLIMQRLEAERR-----ARTAMPAISVLDLLQDE----ERR 1621
+ E EE L Q LE +R+ A+ + A L L+ E E++
Sbjct: 1669 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1728
Query: 1622 RQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAE------EKRRQEEGYYSRLEAERR 1675
RQ LEE R + A ++R+ E E K AE K R EE S E ++
Sbjct: 1729 RQL-LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQ 1787
Query: 1676 RQHDEAAR-RLLEPEAPGL 1693
R EA R R L EA L
Sbjct: 1788 RLEAEAGRFRELAEEAARL 1806
Score = 49.7 bits (117), Expect = 3e-05
Identities = 62/289 (21%), Positives = 123/289 (42%), Gaps = 55/289 (19%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
Q+AA E R+R E + +K A EEE R+R+ ++ +++ + + ++
Sbjct: 1974 QLAAEEERRRREAEERVQKSLAA-EEEAARQRKAALEEVERLKAK----VEEARRLRERA 2028
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
+ E LQ QE + LQ +++ V ++E +L
Sbjct: 2029 EQESARQLQLAQEAAQKRLQAEEKAHAF--------AVQQKEQELQQTL----------- 2069
Query: 1522 KLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEE 1581
QQ+ ++D L E + + R+AEE++ R Q ++ +S+++ E+ E
Sbjct: 2070 ----QQEQSVLDQLRGEAEAAR----RAAEEAEEARV-----QAEREAAQSRRQVEEAER 2116
Query: 1582 EEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQE 1641
+ Q E + +AR A + E+ R++ + E R+ +AE A ++
Sbjct: 2117 ----------LKQSAEEQAQARAQAQAAA-------EKLRKEAEQEAARRAQAEQAALRQ 2159
Query: 1642 EERRRQEEERTKRDAEEKRRQEEGYYSRLEAER-RRQHDEAARRLLEPE 1689
++ E E+ K+ AE+ RQ+ L R + + + + LL+ E
Sbjct: 2160 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2208
Score = 48.9 bits (115), Expect = 4e-05
Identities = 74/326 (22%), Positives = 129/326 (39%), Gaps = 58/326 (17%)
Query: 1393 ANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEE------------------------- 1427
A Q L Q A AE K ++ ++KA++E+
Sbjct: 2152 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2211
Query: 1428 ------ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQ 1481
E R+R + E +L +R Q S L A +++ E + + R ++ R LQ
Sbjct: 2212 LKAEATEAARQRSQVEEELFSVRVQM---EELSKLKA-RIEAENRALILRDKDNTQRFLQ 2267
Query: 1482 PQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQE 1541
+ + + ++V+ +E + L A+E L +Q+ + ML +++Q
Sbjct: 2268 EEAEKMKQVAEEAARLSVAAQEAARLRQL--------AEEDLAQQRAL-AEKMLKEKMQA 2318
Query: 1542 LQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERR 1601
+Q AE ++ L + +RLQE K++ EE T + LEAER+
Sbjct: 2319 VQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEE-----TQGFQRTLEAERQ 2373
Query: 1602 ARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRR 1661
+ M A E R + ++ EM + +A + R++ EE K E
Sbjct: 2374 RQLEMSA---------EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELAT 2424
Query: 1662 QEEGYYSRLEAERRRQHDEAARRLLE 1687
QE+ + +R+Q D A RL E
Sbjct: 2425 QEKVTLVQTLEIQRQQSDHDAERLRE 2450
Score = 48.5 bits (114), Expect = 6e-05
Identities = 70/285 (24%), Positives = 122/285 (42%), Gaps = 37/285 (12%)
Query: 1419 EKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIR 1478
E +K + +EE ER RR+ + + + R + A A+ + EK LQ +E ++
Sbjct: 1486 EAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAR-EKQRALQALEELRLQ 1544
Query: 1479 ELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEK---LEKQ-QQMHI-VD 1533
+ +++ R E + + V+ E + EK LE+ Q+ H+ V
Sbjct: 1545 AEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVA 1604
Query: 1534 MLSKEIQ---ELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTM 1590
L +E + + Q++ +R+ EE++R + WQ + + ++ ++
Sbjct: 1605 QLREEAERRAQQQAEAERAREEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAE 1661
Query: 1591 LIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEE 1650
Q+ EAER AR RR + + + +R+RE A QE E++RQ E
Sbjct: 1662 AEKQKEEAEREAR----------------RRGKAEEQAVRQREL---AEQELEKQRQLAE 1702
Query: 1651 RTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEAPGLCR 1695
T ++R E RL AE + E R+LLE E L R
Sbjct: 1703 GT----AQQRLAAEQELIRLRAE--TEQGEQQRQLLEEELARLQR 1741
Score = 47.4 bits (111), Expect = 1e-04
Identities = 63/292 (21%), Positives = 113/292 (38%), Gaps = 46/292 (15%)
Query: 1422 KARLEEERERKRREQERKLGQMR-----TQSLNPAPFSPLTAQQMKPEKPSTLQRPQETV 1476
KAR E ER R E ++ +R T+ L A + + E+ +R +
Sbjct: 1436 KARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEE 1495
Query: 1477 IRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLS 1536
L+ Q Q + +R + S+ K +A+ EKQ+ + ++ L
Sbjct: 1496 AERLRRQVQDESQRKRQAEVELASRV-------------KAEAEAAREKQRALQALEELR 1542
Query: 1537 KEIQELQSKPDRSAEESDRLRKLMLEW---------------------QFQKRLQESKQK 1575
+ +E + + ++ E R ++ LE Q ++ LQE
Sbjct: 1543 LQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVA 1602
Query: 1576 DEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAE 1635
EE + Q+ EAER A + L +E R + Q EE+ ++++
Sbjct: 1603 VAQLREEAERRAQ-----QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSL 1657
Query: 1636 DRARQEEERRRQEEERTKRDAEEKR--RQEEGYYSRLEAERRRQHDEAARRL 1685
+A E+++ E E +R E++ RQ E LE +R+ A +RL
Sbjct: 1658 AQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1709
Score = 47.0 bits (110), Expect = 2e-04
Identities = 68/323 (21%), Positives = 132/323 (40%), Gaps = 70/323 (21%)
Query: 1404 AAAERRKREEHQRWYEKEKARLEEERE----RKRREQERKLGQMRTQSLNPAPFSPLTAQ 1459
A A RR EE E+AR++ ERE R++ E+ +L Q + + A+
Sbjct: 2083 AEAARRAAEE------AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2136
Query: 1460 QMKPEKPSTLQR---PQETVIRELQP----QQQPRTIERRDLQYITVSKEELSSGDSLSP 1512
+++ E R ++ +R+ Q ++ + + L+ ++EL++
Sbjct: 2137 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTT------ 2190
Query: 1513 DPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQES 1572
+L+ ++ H ++L +E+Q L+++ A E+ R R + E F R+Q
Sbjct: 2191 --------LRLQLEETDHQKNLLDEELQRLKAE----ATEAARQRSQVEEELFSVRVQME 2238
Query: 1573 KQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEE---- 1628
+ + R+EAE RA + LQ+E + +Q EE
Sbjct: 2239 ELSK---------------LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARL 2283
Query: 1629 ---------MRKREAEDRARQE-------EERRRQEEERTKRDAEEKRRQEEGYYSRLEA 1672
+R+ ED A+Q +E+ + +E T+ AE + Q++ ++ +A
Sbjct: 2284 SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQA 2343
Query: 1673 ERRRQHDEAARRLLEPEAPGLCR 1695
R ++ E + L E G R
Sbjct: 2344 RRLQEDKEQMAQQLAEETQGFQR 2366
Score = 43.9 bits (102), Expect = 0.001
Identities = 71/291 (24%), Positives = 127/291 (43%), Gaps = 29/291 (9%)
Query: 1413 EHQR-WYEKEKARLEEERE---RKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPST 1468
+HQ+ ++E RL+ E R+R + E +L +R Q S L A+ ++ E +
Sbjct: 2199 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQM---EELSKLKAR-IEAENRAL 2254
Query: 1469 LQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQ 1528
+ R ++ R LQ + + + ++V+ +E + L A+E L +Q+
Sbjct: 2255 ILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQL--------AEEDLAQQRA 2306
Query: 1529 MHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVD 1588
+ ML +++Q +Q AE ++ L + +RLQE K++ EE
Sbjct: 2307 L-AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQ 2365
Query: 1589 TMLIMQR-------LEAER-RARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQ 1640
L +R EAER + R A + + +D +R R+Q E K + A Q
Sbjct: 2366 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2425
Query: 1641 EEERRRQ--EEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
E+ Q E +R + D + +R +E + LE E+ + EA L+ E
Sbjct: 2426 EKVTLVQTLEIQRQQSDHDAERLREA--IAELEREKEKLQQEAKLLQLKSE 2474
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 67.8 bits (164), Expect = 9e-11
Identities = 74/316 (23%), Positives = 147/316 (46%), Gaps = 53/316 (16%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
Q A AE+ +E+ Q E + + E E +Q+++L Q + + L Q+
Sbjct: 2272 QRALAEKMLKEKMQAVQEATRLKAEAEL----LQQQKELAQEQARRL----------QED 2317
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
K + L + R L+ ++Q + + + + + E+S + + + +R K+
Sbjct: 2318 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2377
Query: 1522 KLEKQQQMHIVDMLSKE----IQELQSKPDRSAEESDRLRKLM--LEWQFQKRLQESKQK 1575
E +++H ++ ++E +Q L+ + +S +++RLR+ + LE + +K QE+K
Sbjct: 2378 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2437
Query: 1576 DEDDEEEED------------------DDVDTMLIMQRLEAERRARTAM---PAISVLDL 1614
EE + + D++L +R + +A+ ++
Sbjct: 2438 QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ 2497
Query: 1615 LQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAER 1674
L++E++R+QQQ+E+ R+R A EE RRRQ E AEE R+++ +LE +R
Sbjct: 2498 LREEQQRQQQQMEQERQRLV---ASMEEARRRQHE------AEEGVRRKQEELQQLEQQR 2548
Query: 1675 RRQHD---EAARRLLE 1687
R+Q + E +RL E
Sbjct: 2549 RQQEELLAEENQRLRE 2564
Score = 65.1 bits (157), Expect = 6e-10
Identities = 77/315 (24%), Positives = 134/315 (42%), Gaps = 36/315 (11%)
Query: 1401 AQVAAAERRKREEHQRWYEKEKA----RLEEERERKRREQERKLGQMRTQSLNPAPFSPL 1456
A++A E+ E R +++A RLEE+ + + + E +L Q+R S S L
Sbjct: 1820 AEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKAS-----DSEL 1874
Query: 1457 TAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK 1516
Q+ E +R E I L+ + + +L+ EL S + D +
Sbjct: 1875 ERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELEL------ELGRIRSNAEDTLR 1928
Query: 1517 RDAKEKLEKQQQMHIV---DMLSKEIQELQSKPDRSAEESDRLRKLMLEW--QFQKRLQE 1571
+ +LE +Q + + +E +E K + EE+ R RK LE + + +++E
Sbjct: 1929 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 1988
Query: 1572 SKQKDEDDEEEEDDDVDTM--LIMQRLEAERRA-------------RTAMPAISVLDLLQ 1616
+++ E E+E + +RL+AE +A +T SVLD L+
Sbjct: 1989 ARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR 2048
Query: 1617 DEERRRQQQLEEMRKREAEDRARQEEERRRQEE-ERTKRDAEEKRRQEEGYYSRLEAERR 1675
E ++ EE + + + RR+ EE ER K+ AEE+ + + E R+
Sbjct: 2049 GEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK 2108
Query: 1676 RQHDEAARRLLEPEA 1690
EAARR +A
Sbjct: 2109 EAEQEAARRAQAEQA 2123
Score = 63.9 bits (154), Expect = 1e-09
Identities = 79/314 (25%), Positives = 139/314 (44%), Gaps = 41/314 (13%)
Query: 1395 QIGLPSAQVAAAERRKREEHQRWYEKEKARLEE---ERERKRREQERKLGQMRTQSLNPA 1451
Q+ AQ A R+ +E Q+ ++E R EE + ++++R + +L Q+R S
Sbjct: 1342 QLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1401
Query: 1452 PFSPLTAQQMKPEKPSTLQRPQET-VIR-ELQPQQQPRTIERRDLQYITVSKEELSSGDS 1509
A+Q + + S L+ +E V+R +L+ ++ R +LQ + EE +
Sbjct: 1402 QAK---ARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQ-- 1456
Query: 1510 LSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQ---ELQSKPDRSAE---ESDRLRKLMLEW 1563
KR A+E+ E+ ++ + D ++ Q EL S+ AE E R + + E
Sbjct: 1457 ------KRQAQEEAERLRRQ-VQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1509
Query: 1564 QFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPA--------------I 1609
+ Q E + + + E V + EAE +++ A A +
Sbjct: 1510 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1569
Query: 1610 SVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSR 1669
+V L ++ ERR QQQ E R RE +R + + + E R + AEE +Q+ S
Sbjct: 1570 AVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQK----SL 1625
Query: 1670 LEAERRRQHDEAAR 1683
+AE +Q +EA R
Sbjct: 1626 AQAEAEKQKEEAER 1639
Score = 57.4 bits (137), Expect = 1e-07
Identities = 83/341 (24%), Positives = 138/341 (40%), Gaps = 77/341 (22%)
Query: 1409 RKREEHQRWYEKEKARLEEERERKRR-----EQERKLGQMRTQSLNPAPFSPLTAQQMKP 1463
R+ EE +R E+++A EERER E++R+L + Q+ Q +
Sbjct: 1310 RRMEEEERLAEQQRA---EERERLAEVEAALEKQRQLAEAHAQA----------KAQAER 1356
Query: 1464 EKPSTLQRPQETVIRE----LQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDA 1519
E QR QE V+R + QQQ R+I+ +LQ + S E + + +R
Sbjct: 1357 EAKELQQRMQEEVVRREEAAVDAQQQKRSIQE-ELQQLRQSSEAEIQAKARQAEAAERS- 1414
Query: 1520 KEKLEKQQQMHIVDM------------------LSKEIQELQSKPDRSAEESDRLRKLML 1561
+L ++++ +V + L +E +++ ++ EE++RLR+ +
Sbjct: 1415 --RLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1472
Query: 1562 EWQFQKRLQE----SKQKDEDDEEEEDDDVDTMLIMQRL---EAERRARTAMP--AISVL 1612
+ +KR E S+ K E + E L RL EAERR R A A V
Sbjct: 1473 DESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQ 1532
Query: 1613 DLLQDEERRRQQQLEEMR------------------------KREAEDRARQEEERRRQE 1648
L+ +R + +L+ R + EAE RA+Q+ E R
Sbjct: 1533 VALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAR 1592
Query: 1649 EERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
EE + + + E RL+AE Q A+ E +
Sbjct: 1593 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQ 1633
Score = 54.3 bits (129), Expect = 1e-06
Identities = 67/278 (24%), Positives = 118/278 (42%), Gaps = 51/278 (18%)
Query: 1406 AERRKREEHQRWYEKEKARLEE-ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPE 1464
AER+++ E E+ K R+ E R + R E++ + + + + + A Q K
Sbjct: 2338 AERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT 2397
Query: 1465 KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLE 1524
TL E+Q QQ ER + +E+ + +++AK
Sbjct: 2398 LVQTL---------EIQRQQSDHDAERLREAIAELEREK---------EKLQQEAKLLQL 2439
Query: 1525 KQQQMHIVDMLSKEIQELQSKPDRSAEESDRL---------RKLMLEWQFQKRLQESKQK 1575
K ++M V + +QE Q+ E D L K LE FQ + +++Q
Sbjct: 2440 KSEEMQTVQQ-EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL 2498
Query: 1576 DEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAE 1635
E+ + ++ Q++E ER+ A +E RRRQ + EE +R+ E
Sbjct: 2499 REEQQRQQ----------QQMEQERQRLVAS---------MEEARRRQHEAEEGVRRKQE 2539
Query: 1636 DRARQEEERRRQEE---ERTKRDAEEKRRQEEGYYSRL 1670
+ + E++RR+QEE E +R E+ + EE + + L
Sbjct: 2540 ELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2577
Score = 53.1 bits (126), Expect = 2e-06
Identities = 82/330 (24%), Positives = 141/330 (42%), Gaps = 47/330 (14%)
Query: 1398 LPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLT 1457
+P A A + R+E E E R E+ E +R ++ + ++ L +
Sbjct: 1204 MPLADSQAVREQLRQEQALLEEIE--RHGEKVEECQRFAKQYINAIKDYELQLVTYKAQL 1261
Query: 1458 AQQMKPEKPSTLQRPQETVIRELQPQQ----QPRTIERRDLQYITVSKEELSSGDSLSPD 1513
P K +Q E+VI+E + + T+ + +++I+ + + + L+ +
Sbjct: 1262 EPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLA-E 1320
Query: 1514 PWKRDAKEKL-------EKQQQMHIVDMLSKEIQELQSKP--DRSAEESDRLRKLMLEWQ 1564
+ + +E+L EKQ+Q+ +K E ++K R EE R + ++ Q
Sbjct: 1321 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQ 1380
Query: 1565 FQKR-LQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQ 1623
QKR +QE Q+ E E ++ EA R+R + + LQ E RQ
Sbjct: 1381 QQKRSIQEELQQLRQSSEAE-----IQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQ 1435
Query: 1624 Q-----QLEEMRKR----EAEDRARQEE----ERRRQEEERTKRDAE-----------EK 1659
+ +L+ +R R EA+ R QEE R+ Q+E + KR AE E
Sbjct: 1436 RGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1495
Query: 1660 RRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
R+++ LE E R Q +EA RRL + E
Sbjct: 1496 AREKQRALQALE-ELRLQAEEAERRLRQAE 1524
Score = 52.8 bits (125), Expect = 3e-06
Identities = 84/343 (24%), Positives = 145/343 (42%), Gaps = 71/343 (20%)
Query: 1406 AERRKREEHQRWYEKEKARLEEERE---RKRREQERKLGQMRTQSLNPAPFSPLTAQQMK 1462
AE + E+ ++ E+E ARL+ E +KR+E E +L ++R A L A + +
Sbjct: 1688 AETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR------AEMEVLLASKAR 1741
Query: 1463 PEKPSTLQRPQETVIRELQPQQ-QPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
E+ S + E + L+ + + R + + +++E D ++ A+
Sbjct: 1742 AEEES--RSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEA 1799
Query: 1522 KLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKR-LQESKQKDEDDE 1580
+ +++ + ++ E + E++RLR+L + FQ+R L+E + + D
Sbjct: 1800 ERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADI 1859
Query: 1581 EEE--------DDDVDTM--LIMQRLEAERRARTAMPAISVL------------------ 1612
EE D +++ L+ L R+ + A+
Sbjct: 1860 EERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRI 1919
Query: 1613 -----DLLQDEERR-----RQQQL---EEMRKREAEDRARQ----EEERRRQ------EE 1649
D L+ +E+ RQ+QL EE R+REAE+R ++ EEE RQ E
Sbjct: 1920 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 1979
Query: 1650 ERTKRDAEEKRRQEEGYYSRLEAERRRQ---HDEAARRLLEPE 1689
ER K EE RR E R E E RQ EAA++ L+ E
Sbjct: 1980 ERLKAKVEEARRLRE----RAEQESARQLQLAQEAAQKRLQAE 2018
Score = 50.4 bits (119), Expect = 2e-05
Identities = 76/291 (26%), Positives = 121/291 (41%), Gaps = 36/291 (12%)
Query: 1403 VAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMK 1462
+A AE K++E + + + EE+ R+R E++L + R + TAQQ
Sbjct: 1625 LAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR-------QLAEGTAQQRL 1677
Query: 1463 PEKPSTLQRPQETVIRELQPQQQPRTIER--RDLQYITVSKEELSSGDSLSPDPWKRDAK 1520
+ ++ ET E Q Q + R R+ T ++EL + + +
Sbjct: 1678 AAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLA 1737
Query: 1521 EKLEKQQQMHIVDMLSKEIQELQSKPDRS-AEESDRLRKLMLEWQFQKRLQESKQKDEDD 1579
K +++ SK+ E ++ R AEE+ RLR L E + Q++L E ED
Sbjct: 1738 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE-----ED- 1791
Query: 1580 EEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEER---RRQQQLEEMRKREAED 1636
QR EAER + AI L+ E + ++ E +R AED
Sbjct: 1792 -----------AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1840
Query: 1637 RARQEEERRRQEEE--RTKRDAEEKRRQ-EEGYYSRLEAERRRQHDEAARR 1684
A Q RRR EE+ + K D EE+ Q + S LE ++ D +R
Sbjct: 1841 EAFQ---RRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1888
Score = 50.1 bits (118), Expect = 2e-05
Identities = 86/319 (26%), Positives = 133/319 (41%), Gaps = 41/319 (12%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
QV +RKR+ + KA E RE++R Q L ++R Q A + +Q
Sbjct: 1470 QVQDESQRKRQAEVELASRVKAEAEAAREKQRALQA--LEELRLQ----AEEAERRLRQA 1523
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
+ E+ +Q ET R + + Q + R T E + ++ + +A+
Sbjct: 1524 EVERARQVQVALETAQRSAEAELQSK---RASFAEKTAQLERSLQEEHVAVAQLREEAER 1580
Query: 1522 KLEKQQQMHIV-DMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQES---KQKDE 1577
+ ++Q + + +E++ Q K A E+ RLR E QK L ++ KQK+E
Sbjct: 1581 RAQQQAEAERAREEAERELERWQLK----ANEALRLRLQAEEVAQQKSLAQAEAEKQKEE 1636
Query: 1578 DDEE-------EEDDDVDTMLIMQRLEAERR-----ARTAMPAISVLDLLQDE----ERR 1621
+ E EE L Q LE +R+ A+ + A L L+ E E++
Sbjct: 1637 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1696
Query: 1622 RQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAE------EKRRQEEGYYSRLEAERR 1675
RQ LEE R + A ++R+ E E K AE K R EE S E ++
Sbjct: 1697 RQL-LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQ 1755
Query: 1676 RQHDEAAR-RLLEPEAPGL 1693
R EA R R L EA L
Sbjct: 1756 RLEAEAGRFRELAEEAARL 1774
Score = 49.7 bits (117), Expect = 3e-05
Identities = 62/289 (21%), Positives = 123/289 (42%), Gaps = 55/289 (19%)
Query: 1402 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1461
Q+AA E R+R E + +K A EEE R+R+ ++ +++ + + ++
Sbjct: 1942 QLAAEEERRRREAEERVQKSLAA-EEEAARQRKAALEEVERLKAK----VEEARRLRERA 1996
Query: 1462 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1521
+ E LQ QE + LQ +++ V ++E +L
Sbjct: 1997 EQESARQLQLAQEAAQKRLQAEEKAHAF--------AVQQKEQELQQTL----------- 2037
Query: 1522 KLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEE 1581
QQ+ ++D L E + + R+AEE++ R Q ++ +S+++ E+ E
Sbjct: 2038 ----QQEQSVLDQLRGEAEAAR----RAAEEAEEARV-----QAEREAAQSRRQVEEAER 2084
Query: 1582 EEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQE 1641
+ Q E + +AR A + E+ R++ + E R+ +AE A ++
Sbjct: 2085 ----------LKQSAEEQAQARAQAQAAA-------EKLRKEAEQEAARRAQAEQAALRQ 2127
Query: 1642 EERRRQEEERTKRDAEEKRRQEEGYYSRLEAER-RRQHDEAARRLLEPE 1689
++ E E+ K+ AE+ RQ+ L R + + + + LL+ E
Sbjct: 2128 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2176
Score = 48.9 bits (115), Expect = 4e-05
Identities = 74/326 (22%), Positives = 129/326 (39%), Gaps = 58/326 (17%)
Query: 1393 ANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEE------------------------- 1427
A Q L Q A AE K ++ ++KA++E+
Sbjct: 2120 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2179
Query: 1428 ------ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQ 1481
E R+R + E +L +R Q S L A +++ E + + R ++ R LQ
Sbjct: 2180 LKAEATEAARQRSQVEEELFSVRVQM---EELSKLKA-RIEAENRALILRDKDNTQRFLQ 2235
Query: 1482 PQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQE 1541
+ + + ++V+ +E + L A+E L +Q+ + ML +++Q
Sbjct: 2236 EEAEKMKQVAEEAARLSVAAQEAARLRQL--------AEEDLAQQRAL-AEKMLKEKMQA 2286
Query: 1542 LQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERR 1601
+Q AE ++ L + +RLQE K++ EE T + LEAER+
Sbjct: 2287 VQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEE-----TQGFQRTLEAERQ 2341
Query: 1602 ARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRR 1661
+ M A E R + ++ EM + +A + R++ EE K E
Sbjct: 2342 RQLEMSA---------EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELAT 2392
Query: 1662 QEEGYYSRLEAERRRQHDEAARRLLE 1687
QE+ + +R+Q D A RL E
Sbjct: 2393 QEKVTLVQTLEIQRQQSDHDAERLRE 2418
Score = 48.5 bits (114), Expect = 6e-05
Identities = 70/285 (24%), Positives = 122/285 (42%), Gaps = 37/285 (12%)
Query: 1419 EKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIR 1478
E +K + +EE ER RR+ + + + R + A A+ + EK LQ +E ++
Sbjct: 1454 EAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAR-EKQRALQALEELRLQ 1512
Query: 1479 ELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEK---LEKQ-QQMHI-VD 1533
+ +++ R E + + V+ E + EK LE+ Q+ H+ V
Sbjct: 1513 AEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVA 1572
Query: 1534 MLSKEIQ---ELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTM 1590
L +E + + Q++ +R+ EE++R + WQ + + ++ ++
Sbjct: 1573 QLREEAERRAQQQAEAERAREEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAE 1629
Query: 1591 LIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEE 1650
Q+ EAER AR RR + + + +R+RE A QE E++RQ E
Sbjct: 1630 AEKQKEEAEREAR----------------RRGKAEEQAVRQREL---AEQELEKQRQLAE 1670
Query: 1651 RTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPEAPGLCR 1695
T ++R E RL AE + E R+LLE E L R
Sbjct: 1671 GT----AQQRLAAEQELIRLRAE--TEQGEQQRQLLEEELARLQR 1709
Score = 47.4 bits (111), Expect = 1e-04
Identities = 63/292 (21%), Positives = 113/292 (38%), Gaps = 46/292 (15%)
Query: 1422 KARLEEERERKRREQERKLGQMR-----TQSLNPAPFSPLTAQQMKPEKPSTLQRPQETV 1476
KAR E ER R E ++ +R T+ L A + + E+ +R +
Sbjct: 1404 KARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEE 1463
Query: 1477 IRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLS 1536
L+ Q Q + +R + S+ K +A+ EKQ+ + ++ L
Sbjct: 1464 AERLRRQVQDESQRKRQAEVELASRV-------------KAEAEAAREKQRALQALEELR 1510
Query: 1537 KEIQELQSKPDRSAEESDRLRKLMLEW---------------------QFQKRLQESKQK 1575
+ +E + + ++ E R ++ LE Q ++ LQE
Sbjct: 1511 LQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVA 1570
Query: 1576 DEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKREAE 1635
EE + Q+ EAER A + L +E R + Q EE+ ++++
Sbjct: 1571 VAQLREEAERRAQ-----QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSL 1625
Query: 1636 DRARQEEERRRQEEERTKRDAEEKR--RQEEGYYSRLEAERRRQHDEAARRL 1685
+A E+++ E E +R E++ RQ E LE +R+ A +RL
Sbjct: 1626 AQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1677
Score = 47.0 bits (110), Expect = 2e-04
Identities = 68/323 (21%), Positives = 132/323 (40%), Gaps = 70/323 (21%)
Query: 1404 AAAERRKREEHQRWYEKEKARLEEERE----RKRREQERKLGQMRTQSLNPAPFSPLTAQ 1459
A A RR EE E+AR++ ERE R++ E+ +L Q + + A+
Sbjct: 2051 AEAARRAAEE------AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2104
Query: 1460 QMKPEKPSTLQR---PQETVIRELQP----QQQPRTIERRDLQYITVSKEELSSGDSLSP 1512
+++ E R ++ +R+ Q ++ + + L+ ++EL++
Sbjct: 2105 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTT------ 2158
Query: 1513 DPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQES 1572
+L+ ++ H ++L +E+Q L+++ A E+ R R + E F R+Q
Sbjct: 2159 --------LRLQLEETDHQKNLLDEELQRLKAE----ATEAARQRSQVEEELFSVRVQME 2206
Query: 1573 KQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEE---- 1628
+ + R+EAE RA + LQ+E + +Q EE
Sbjct: 2207 ELSK---------------LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARL 2251
Query: 1629 ---------MRKREAEDRARQE-------EERRRQEEERTKRDAEEKRRQEEGYYSRLEA 1672
+R+ ED A+Q +E+ + +E T+ AE + Q++ ++ +A
Sbjct: 2252 SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQA 2311
Query: 1673 ERRRQHDEAARRLLEPEAPGLCR 1695
R ++ E + L E G R
Sbjct: 2312 RRLQEDKEQMAQQLAEETQGFQR 2334
Score = 43.9 bits (102), Expect = 0.001
Identities = 71/291 (24%), Positives = 127/291 (43%), Gaps = 29/291 (9%)
Query: 1413 EHQR-WYEKEKARLEEERE---RKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPST 1468
+HQ+ ++E RL+ E R+R + E +L +R Q S L A+ ++ E +
Sbjct: 2167 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQM---EELSKLKAR-IEAENRAL 2222
Query: 1469 LQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQ 1528
+ R ++ R LQ + + + ++V+ +E + L A+E L +Q+
Sbjct: 2223 ILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQL--------AEEDLAQQRA 2274
Query: 1529 MHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVD 1588
+ ML +++Q +Q AE ++ L + +RLQE K++ EE
Sbjct: 2275 L-AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQ 2333
Query: 1589 TMLIMQR-------LEAER-RARTAMPAISVLDLLQDEERRRQQQLEEMRKREAEDRARQ 1640
L +R EAER + R A + + +D +R R+Q E K + A Q
Sbjct: 2334 RTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQ 2393
Query: 1641 EEERRRQ--EEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLLEPE 1689
E+ Q E +R + D + +R +E + LE E+ + EA L+ E
Sbjct: 2394 EKVTLVQTLEIQRQQSDHDAERLREA--IAELEREKEKLQQEAKLLQLKSE 2442
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,486,507
Number of Sequences: 37866
Number of extensions: 4498811
Number of successful extensions: 71858
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 784
Number of HSP's successfully gapped in prelim test: 1609
Number of HSP's that attempted gapping in prelim test: 29589
Number of HSP's gapped (non-prelim): 23755
length of query: 1834
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1717
effective length of database: 13,817,196
effective search space: 23724125532
effective search space used: 23724125532
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.