Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 90819229
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|90819229 cutaneous T-cell lymphoma-associated antigen 1
isoform 1 [Homo sapiens]
(745 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|90819229 cutaneous T-cell lymphoma-associated antigen 1 isofo... 1509 0.0
gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens] 1303 0.0
gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens] 1303 0.0
gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens] 1303 0.0
gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens] 1201 0.0
gi|56847634 hypothetical protein LOC441294 [Homo sapiens] 1144 0.0
gi|146262005 CTAGE family, member 6 [Homo sapiens] 1140 0.0
gi|224586773 hypothetical protein LOC643854 [Homo sapiens] 1137 0.0
gi|193290160 CTAGE family, member 4 [Homo sapiens] 1131 0.0
gi|122891870 melanoma inhibitory activity family, member 3 [Homo... 226 6e-59
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 83 8e-16
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 82 1e-15
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 82 1e-15
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 82 2e-15
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 82 2e-15
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 82 2e-15
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 81 3e-15
gi|156104908 myosin heavy chain 6 [Homo sapiens] 81 3e-15
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 81 4e-15
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 80 7e-15
gi|118498356 kinectin 1 isoform a [Homo sapiens] 80 9e-15
gi|118498368 kinectin 1 isoform c [Homo sapiens] 80 9e-15
gi|33620775 kinectin 1 isoform a [Homo sapiens] 80 9e-15
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 80 9e-15
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 79 1e-14
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 79 2e-14
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 79 2e-14
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 79 2e-14
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 77 4e-14
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 77 6e-14
>gi|90819229 cutaneous T-cell lymphoma-associated antigen 1 isoform
1 [Homo sapiens]
Length = 745
Score = 1509 bits (3908), Expect = 0.0
Identities = 745/745 (100%), Positives = 745/745 (100%)
Query: 1 MRPDSHPYGFPWELVIRAAVAGFFAVLFLWRSFRSVTSRLYVRREKKFAVALSGLIEEKC 60
MRPDSHPYGFPWELVIRAAVAGFFAVLFLWRSFRSVTSRLYVRREKKFAVALSGLIEEKC
Sbjct: 1 MRPDSHPYGFPWELVIRAAVAGFFAVLFLWRSFRSVTSRLYVRREKKFAVALSGLIEEKC 60
Query: 61 KLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEILCLEK 120
KLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEILCLEK
Sbjct: 61 KLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEILCLEK 120
Query: 121 ELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQD 180
ELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQD
Sbjct: 121 ELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQD 180
Query: 181 AWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTER 240
AWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTER
Sbjct: 181 AWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTER 240
Query: 241 LLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLE 300
LLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLE
Sbjct: 241 LLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLE 300
Query: 301 GERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQ 360
GERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQ
Sbjct: 301 GERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQ 360
Query: 361 ENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFYQK 420
ENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFYQK
Sbjct: 361 ENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFYQK 420
Query: 421 KIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDVPNTA 480
KIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDVPNTA
Sbjct: 421 KIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDVPNTA 480
Query: 481 FGRQHSPYGPSPLGWPSSETRASLYPPTLLEGPLRLSPLLPRGGGRGSRGPGNPPDHQIT 540
FGRQHSPYGPSPLGWPSSETRASLYPPTLLEGPLRLSPLLPRGGGRGSRGPGNPPDHQIT
Sbjct: 481 FGRQHSPYGPSPLGWPSSETRASLYPPTLLEGPLRLSPLLPRGGGRGSRGPGNPPDHQIT 540
Query: 541 KERGESSCDRLTDPHRAPSDAGPLAPPWEQDYRMMFPPPGQSYPDSALPPQRQDRFYSNC 600
KERGESSCDRLTDPHRAPSDAGPLAPPWEQDYRMMFPPPGQSYPDSALPPQRQDRFYSNC
Sbjct: 541 KERGESSCDRLTDPHRAPSDAGPLAPPWEQDYRMMFPPPGQSYPDSALPPQRQDRFYSNC 600
Query: 601 ARLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDNLGNLKVPDSSLPAENEATGPGF 660
ARLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDNLGNLKVPDSSLPAENEATGPGF
Sbjct: 601 ARLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDNLGNLKVPDSSLPAENEATGPGF 660
Query: 661 VPPPLAPIRGLLFPVDTRGPFIRRGPPFPPPPPGTVFGASPDYFSPRDVPGPPRAPFAMR 720
VPPPLAPIRGLLFPVDTRGPFIRRGPPFPPPPPGTVFGASPDYFSPRDVPGPPRAPFAMR
Sbjct: 661 VPPPLAPIRGLLFPVDTRGPFIRRGPPFPPPPPGTVFGASPDYFSPRDVPGPPRAPFAMR 720
Query: 721 NVYLPRGFLPYRPPRPAFFPPAPTF 745
NVYLPRGFLPYRPPRPAFFPPAPTF
Sbjct: 721 NVYLPRGFLPYRPPRPAFFPPAPTF 745
>gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens]
Length = 804
Score = 1303 bits (3373), Expect = 0.0
Identities = 660/745 (88%), Positives = 682/745 (91%), Gaps = 2/745 (0%)
Query: 1 MRPDSHPYGFPWELVIRAAVAGFFAVLF-LWRSFRSVTSRLYVRREKKFAVALSGLIEEK 59
MRPDS+ YGFPWELVI AAV GFFAVLF LWRSFRSV SRLYV REKK A+ LSGLIEEK
Sbjct: 30 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 89
Query: 60 CKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEILCLE 119
KLLEKFSLVQKEYEGYEVESSLK+ASFEKEATEAQSLEATCEKLNR NSEL EILCLE
Sbjct: 90 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE 149
Query: 120 KELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQ 179
KELKEEKSKHSEQ+ELMADISKRIQSLEDESKSLKSQVAEAKMTFK FQ NEERL+I I+
Sbjct: 150 KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK 209
Query: 180 DAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTE 239
DA ENS+LQESQKQLLQEAEVWKEQVSEL KQK TFEDSKVHAEQVLNDKE+HIKTLTE
Sbjct: 210 DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE 269
Query: 240 RLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTL 299
RLLKMKD AML ED+TDDDNLELEMNSESE+GAYLDNPPKGALKKLIHAAKLNASLKTL
Sbjct: 270 RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL 329
Query: 300 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELY 359
EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFE+ENQKLQQKLKVMTELY
Sbjct: 330 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY 389
Query: 360 QENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDL-KEFEKTIHFY 418
QENEMKL+RKL VEE RLEKEEKLSKVDE ISHATEELETYRKRAKDL +E E+TIH Y
Sbjct: 390 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 449
Query: 419 QKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDVPN 478
Q +II HEKKAHDNW AA AERNLNDLRKENAHNRQKLTE E K +LLEKDPY LDVPN
Sbjct: 450 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 509
Query: 479 TAFGRQHSPYGPSPLGWPSSETRASLYPPTLLEGPLRLSPLLPRGGGRGSRGPGNPPDHQ 538
TAFGR+HSPYGPSPLGWPSSETRA L PPTLLEGPLRLSPLLP GGGRGSRGPGNP DHQ
Sbjct: 510 TAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQ 569
Query: 539 ITKERGESSCDRLTDPHRAPSDAGPLAPPWEQDYRMMFPPPGQSYPDSALPPQRQDRFYS 598
IT ERGESSCDRLTDPHRAPSD G L+PPW+QD RMMFPPPGQSYPDSALPPQRQDRF S
Sbjct: 570 ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS 629
Query: 599 NCARLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDNLGNLKVPDSSLPAENEATGP 658
N RLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKD+LGNL VPDSSLPAENEATGP
Sbjct: 630 NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP 689
Query: 659 GFVPPPLAPIRGLLFPVDTRGPFIRRGPPFPPPPPGTVFGASPDYFSPRDVPGPPRAPFA 718
GFVPPPLAPIRG LFPVD RGPF+RRGPPFPPPPPG +FGAS DYF P D PGPP APFA
Sbjct: 690 GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA 749
Query: 719 MRNVYLPRGFLPYRPPRPAFFPPAP 743
MRNVY PRGF PY PPRP FFPP P
Sbjct: 750 MRNVYPPRGFPPYLPPRPGFFPPPP 774
>gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens]
Length = 775
Score = 1303 bits (3373), Expect = 0.0
Identities = 660/745 (88%), Positives = 682/745 (91%), Gaps = 2/745 (0%)
Query: 1 MRPDSHPYGFPWELVIRAAVAGFFAVLF-LWRSFRSVTSRLYVRREKKFAVALSGLIEEK 59
MRPDS+ YGFPWELVI AAV GFFAVLF LWRSFRSV SRLYV REKK A+ LSGLIEEK
Sbjct: 1 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 60
Query: 60 CKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEILCLE 119
KLLEKFSLVQKEYEGYEVESSLK+ASFEKEATEAQSLEATCEKLNR NSEL EILCLE
Sbjct: 61 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE 120
Query: 120 KELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQ 179
KELKEEKSKHSEQ+ELMADISKRIQSLEDESKSLKSQVAEAKMTFK FQ NEERL+I I+
Sbjct: 121 KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK 180
Query: 180 DAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTE 239
DA ENS+LQESQKQLLQEAEVWKEQVSEL KQK TFEDSKVHAEQVLNDKE+HIKTLTE
Sbjct: 181 DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE 240
Query: 240 RLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTL 299
RLLKMKD AML ED+TDDDNLELEMNSESE+GAYLDNPPKGALKKLIHAAKLNASLKTL
Sbjct: 241 RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL 300
Query: 300 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELY 359
EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFE+ENQKLQQKLKVMTELY
Sbjct: 301 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY 360
Query: 360 QENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDL-KEFEKTIHFY 418
QENEMKL+RKL VEE RLEKEEKLSKVDE ISHATEELETYRKRAKDL +E E+TIH Y
Sbjct: 361 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 420
Query: 419 QKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDVPN 478
Q +II HEKKAHDNW AA AERNLNDLRKENAHNRQKLTE E K +LLEKDPY LDVPN
Sbjct: 421 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 480
Query: 479 TAFGRQHSPYGPSPLGWPSSETRASLYPPTLLEGPLRLSPLLPRGGGRGSRGPGNPPDHQ 538
TAFGR+HSPYGPSPLGWPSSETRA L PPTLLEGPLRLSPLLP GGGRGSRGPGNP DHQ
Sbjct: 481 TAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQ 540
Query: 539 ITKERGESSCDRLTDPHRAPSDAGPLAPPWEQDYRMMFPPPGQSYPDSALPPQRQDRFYS 598
IT ERGESSCDRLTDPHRAPSD G L+PPW+QD RMMFPPPGQSYPDSALPPQRQDRF S
Sbjct: 541 ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS 600
Query: 599 NCARLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDNLGNLKVPDSSLPAENEATGP 658
N RLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKD+LGNL VPDSSLPAENEATGP
Sbjct: 601 NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP 660
Query: 659 GFVPPPLAPIRGLLFPVDTRGPFIRRGPPFPPPPPGTVFGASPDYFSPRDVPGPPRAPFA 718
GFVPPPLAPIRG LFPVD RGPF+RRGPPFPPPPPG +FGAS DYF P D PGPP APFA
Sbjct: 661 GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA 720
Query: 719 MRNVYLPRGFLPYRPPRPAFFPPAP 743
MRNVY PRGF PY PPRP FFPP P
Sbjct: 721 MRNVYPPRGFPPYLPPRPGFFPPPP 745
>gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens]
Length = 792
Score = 1303 bits (3373), Expect = 0.0
Identities = 660/745 (88%), Positives = 682/745 (91%), Gaps = 2/745 (0%)
Query: 1 MRPDSHPYGFPWELVIRAAVAGFFAVLF-LWRSFRSVTSRLYVRREKKFAVALSGLIEEK 59
MRPDS+ YGFPWELVI AAV GFFAVLF LWRSFRSV SRLYV REKK A+ LSGLIEEK
Sbjct: 18 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 77
Query: 60 CKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEILCLE 119
KLLEKFSLVQKEYEGYEVESSLK+ASFEKEATEAQSLEATCEKLNR NSEL EILCLE
Sbjct: 78 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE 137
Query: 120 KELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQ 179
KELKEEKSKHSEQ+ELMADISKRIQSLEDESKSLKSQVAEAKMTFK FQ NEERL+I I+
Sbjct: 138 KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK 197
Query: 180 DAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTE 239
DA ENS+LQESQKQLLQEAEVWKEQVSEL KQK TFEDSKVHAEQVLNDKE+HIKTLTE
Sbjct: 198 DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE 257
Query: 240 RLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTL 299
RLLKMKD AML ED+TDDDNLELEMNSESE+GAYLDNPPKGALKKLIHAAKLNASLKTL
Sbjct: 258 RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL 317
Query: 300 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELY 359
EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFE+ENQKLQQKLKVMTELY
Sbjct: 318 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY 377
Query: 360 QENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDL-KEFEKTIHFY 418
QENEMKL+RKL VEE RLEKEEKLSKVDE ISHATEELETYRKRAKDL +E E+TIH Y
Sbjct: 378 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 437
Query: 419 QKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDVPN 478
Q +II HEKKAHDNW AA AERNLNDLRKENAHNRQKLTE E K +LLEKDPY LDVPN
Sbjct: 438 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 497
Query: 479 TAFGRQHSPYGPSPLGWPSSETRASLYPPTLLEGPLRLSPLLPRGGGRGSRGPGNPPDHQ 538
TAFGR+HSPYGPSPLGWPSSETRA L PPTLLEGPLRLSPLLP GGGRGSRGPGNP DHQ
Sbjct: 498 TAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQ 557
Query: 539 ITKERGESSCDRLTDPHRAPSDAGPLAPPWEQDYRMMFPPPGQSYPDSALPPQRQDRFYS 598
IT ERGESSCDRLTDPHRAPSD G L+PPW+QD RMMFPPPGQSYPDSALPPQRQDRF S
Sbjct: 558 ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS 617
Query: 599 NCARLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDNLGNLKVPDSSLPAENEATGP 658
N RLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKD+LGNL VPDSSLPAENEATGP
Sbjct: 618 NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP 677
Query: 659 GFVPPPLAPIRGLLFPVDTRGPFIRRGPPFPPPPPGTVFGASPDYFSPRDVPGPPRAPFA 718
GFVPPPLAPIRG LFPVD RGPF+RRGPPFPPPPPG +FGAS DYF P D PGPP APFA
Sbjct: 678 GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA 737
Query: 719 MRNVYLPRGFLPYRPPRPAFFPPAP 743
MRNVY PRGF PY PPRP FFPP P
Sbjct: 738 MRNVYPPRGFPPYLPPRPGFFPPPP 762
>gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]
Length = 761
Score = 1201 bits (3107), Expect = 0.0
Identities = 621/745 (83%), Positives = 642/745 (86%), Gaps = 45/745 (6%)
Query: 1 MRPDSHPYGFPWELVIRAAVAGFFAVLF-LWRSFRSVTSRLYVRREKKFAVALSGLIEEK 59
MRPDS+ YGFPWELVI AAV GFFAVLF LWRSFRSV SRLYV REKK A+ LSGLIEEK
Sbjct: 30 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 89
Query: 60 CKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEILCLE 119
KLLEKFSLVQKEYEGYEVESSLK+ASFEKEATEAQSLEATCEKLNR NSEL EILCLE
Sbjct: 90 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLE 149
Query: 120 KELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQ 179
KELKEEKSKHSEQ+ELMADISKRIQSLEDESKSLKSQVAEAKMTFK FQ NEERL+I I+
Sbjct: 150 KELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIK 209
Query: 180 DAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTE 239
DA ENS+LQESQKQLLQEAEVWKEQVSEL KQK TFEDSKVHAEQVLNDKE+HIKTLTE
Sbjct: 210 DALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTE 269
Query: 240 RLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTL 299
RLLKMKD AML ED+TDDDNLELEMNSESE+GAYLDNPPKGALKKLIHAAKLNASLKTL
Sbjct: 270 RLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTL 329
Query: 300 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELY 359
EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFE+ENQKLQQKLKVMTELY
Sbjct: 330 EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELY 389
Query: 360 QENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDL-KEFEKTIHFY 418
QENEMKL+RKL VEE RLEKEEKLSKVDE ISHATEELETYRKRAKDL +E E+TIH Y
Sbjct: 390 QENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSY 449
Query: 419 QKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDVPN 478
Q +II HEKKAHDNW AA AERNLNDLRKENAHNRQKLTE E K +LLEKDPY LDVPN
Sbjct: 450 QGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPN 509
Query: 479 TAFGRQHSPYGPSPLGWPSSETRASLYPPTLLEGPLRLSPLLPRGGGRGSRGPGNPPDHQ 538
TAFG RGSRGPGNP DHQ
Sbjct: 510 TAFG-------------------------------------------RGSRGPGNPLDHQ 526
Query: 539 ITKERGESSCDRLTDPHRAPSDAGPLAPPWEQDYRMMFPPPGQSYPDSALPPQRQDRFYS 598
IT ERGESSCDRLTDPHRAPSD G L+PPW+QD RMMFPPPGQSYPDSALPPQRQDRF S
Sbjct: 527 ITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCS 586
Query: 599 NCARLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDNLGNLKVPDSSLPAENEATGP 658
N RLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKD+LGNL VPDSSLPAENEATGP
Sbjct: 587 NSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGP 646
Query: 659 GFVPPPLAPIRGLLFPVDTRGPFIRRGPPFPPPPPGTVFGASPDYFSPRDVPGPPRAPFA 718
GFVPPPLAPIRG LFPVD RGPF+RRGPPFPPPPPG +FGAS DYF P D PGPP APFA
Sbjct: 647 GFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFA 706
Query: 719 MRNVYLPRGFLPYRPPRPAFFPPAP 743
MRNVY PRGF PY PPRP FFPP P
Sbjct: 707 MRNVYPPRGFPPYLPPRPGFFPPPP 731
>gi|56847634 hypothetical protein LOC441294 [Homo sapiens]
Length = 777
Score = 1144 bits (2960), Expect = 0.0
Identities = 583/744 (78%), Positives = 638/744 (85%), Gaps = 4/744 (0%)
Query: 1 MRPDSHPYGFPWELVIRAAVAGFFAVL-FLWRSFRSVTSRLYVRREKKFAVALSGLIEEK 59
MRPD +PYGFP ELV+ AAV GFF VL FLWRSFRSV SRLYV RE+K LSGLIEEK
Sbjct: 30 MRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGATLSGLIEEK 89
Query: 60 CKLLEKFSLVQKEYEGYEVESSLKNASFEKEATE-AQSLEATCEKLNRFNSELVHEILCL 118
CKLLEKFSL+QKEYEGYEVESSL++ASFEK A E A+SLEATCEKLNR NSEL EILCL
Sbjct: 90 CKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDEILCL 149
Query: 119 EKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEI 178
EK+LKEEKSKHS+Q+ELMADISK IQSLEDESKSLKSQ+AEAK+ K F+ +EER I I
Sbjct: 150 EKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAI 209
Query: 179 QDAWKENSELQESQKQLLQ-EAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTL 237
+DA ENS+LQ S KQL Q EAEVWK QVSEL KQK TFEDSKVHAEQVLNDKENHIKTL
Sbjct: 210 KDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTL 269
Query: 238 TERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLK 297
T L MKD A+LEED TDDDNLELE+NS+ E+GA LD+P KGALKKLIHAAKLN SLK
Sbjct: 270 TGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLK 329
Query: 298 TLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTE 357
+LEGERN I IQLSEVDKTKEELTEHIKNLQT+QASLQSEN +FESENQKLQQKLK+MTE
Sbjct: 330 SLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTE 389
Query: 358 LYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKE-FEKTIH 416
YQENEMKLYRKL VEE R+E+EEKLS+V+E +S ATE+LETYRK AKDL+E E+T+H
Sbjct: 390 FYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKLSRATEQLETYRKLAKDLEEELERTVH 449
Query: 417 FYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDV 476
FYQK++I +EK+ HDNW AA TAERNL+DLRKENAHN+QKLTE E K +LLEKDP LDV
Sbjct: 450 FYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNALDV 509
Query: 477 PNTAFGRQHSPYGPSPLGWPSSETRASLYPPTLLEGPLRLSPLLPRGGGRGSRGPGNPPD 536
NTAFGR+H+P GP+PLG SSETRA L P TLLE PL LSP+LP GGGRG RGPGNP D
Sbjct: 510 SNTAFGREHAPNGPAPLGQRSSETRAFLSPQTLLEDPLGLSPVLPEGGGRGPRGPGNPLD 569
Query: 537 HQITKERGESSCDRLTDPHRAPSDAGPLAPPWEQDYRMMFPPPGQSYPDSALPPQRQDRF 596
HQIT ERGE SCDRLTDPHRAPSD G L+ P EQD +MMFPPPGQSYPDSALPPQR+DRF
Sbjct: 570 HQITNERGEPSCDRLTDPHRAPSDTGSLSSPVEQDCKMMFPPPGQSYPDSALPPQREDRF 629
Query: 597 YSNCARLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDNLGNLKVPDSSLPAENEAT 656
YSN RLSG AE RSF M SLDKMDGSMPSEMESSRND KD+LGNL VPDSSLPAENEAT
Sbjct: 630 YSNSERLSGSAEPRSFKMTSLDKMDGSMPSEMESSRNDAKDDLGNLNVPDSSLPAENEAT 689
Query: 657 GPGFVPPPLAPIRGLLFPVDTRGPFIRRGPPFPPPPPGTVFGASPDYFSPRDVPGPPRAP 716
GPGF+PPPLAP+RG LFPVDTRGPF+RRGPPFPPPPPGT+FGAS YF PRD PGPP AP
Sbjct: 690 GPGFIPPPLAPVRGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRDFPGPPHAP 749
Query: 717 FAMRNVYLPRGFLPYRPPRPAFFP 740
FAMRN+Y PRG PY PRP F+P
Sbjct: 750 FAMRNIYPPRGLPPYFHPRPGFYP 773
>gi|146262005 CTAGE family, member 6 [Homo sapiens]
Length = 777
Score = 1140 bits (2950), Expect = 0.0
Identities = 581/744 (78%), Positives = 637/744 (85%), Gaps = 4/744 (0%)
Query: 1 MRPDSHPYGFPWELVIRAAVAGFFAVL-FLWRSFRSVTSRLYVRREKKFAVALSGLIEEK 59
MRPD +PYGFP ELV+ AAV GFF VL FLWRSFRSV SRLYV RE+K LSGLIEEK
Sbjct: 30 MRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGATLSGLIEEK 89
Query: 60 CKLLEKFSLVQKEYEGYEVESSLKNASFEKEATE-AQSLEATCEKLNRFNSELVHEILCL 118
CKLLEKFSL+QKEYEGYEVESSL++ASFEK A E A+SLEATCEKLNR NSEL EILCL
Sbjct: 90 CKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDEILCL 149
Query: 119 EKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEI 178
EK+LKEEKSKHS+Q+ELMADISK IQSLEDESKSLKSQ+AEAK+ K F+ +EER I I
Sbjct: 150 EKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAI 209
Query: 179 QDAWKENSELQESQKQLLQ-EAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTL 237
+DA ENS+LQ S KQL Q EAEVWK +VSEL KQK TFEDSKVHAEQVLNDKENHIKTL
Sbjct: 210 KDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTL 269
Query: 238 TERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLK 297
T L MKD A+LEED TDDDNLELE+NS+ E+GA LD+P KGALKKLIHAAKLN SLK
Sbjct: 270 TGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLK 329
Query: 298 TLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTE 357
+LEGERN I IQLSEVDKTKEELTEHIKNLQT+Q SLQSEN +FESENQKLQQKLK+MTE
Sbjct: 330 SLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTE 389
Query: 358 LYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKE-FEKTIH 416
YQE+EMKLYRKL VEE R+E+EEKLSKV+E +S ATE+LETYRK AKDL+E E+T+H
Sbjct: 390 FYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVH 449
Query: 417 FYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDV 476
FYQK++I +EK+ HDNW AA TAERNL+DLRKENAHN+QKLTE E K +LLEKDP LDV
Sbjct: 450 FYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNALDV 509
Query: 477 PNTAFGRQHSPYGPSPLGWPSSETRASLYPPTLLEGPLRLSPLLPRGGGRGSRGPGNPPD 536
NTAFGR+H+P GP+PLG SSETRA L P TLLE PL LSP+LP GGGRG RGPGNP D
Sbjct: 510 SNTAFGREHAPNGPAPLGQRSSETRAFLSPQTLLEDPLGLSPVLPEGGGRGPRGPGNPLD 569
Query: 537 HQITKERGESSCDRLTDPHRAPSDAGPLAPPWEQDYRMMFPPPGQSYPDSALPPQRQDRF 596
HQIT ERGE SCDRLTDPHRAPSD G L+ P EQD +MMFPPPGQSYPDSALPPQR+DRF
Sbjct: 570 HQITNERGEPSCDRLTDPHRAPSDTGSLSSPVEQDCKMMFPPPGQSYPDSALPPQREDRF 629
Query: 597 YSNCARLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDNLGNLKVPDSSLPAENEAT 656
YSN RLSG AE RSF M SLDKMDGSMPSEMESSRND KD+LGNL VPDSSLPAENEAT
Sbjct: 630 YSNSERLSGSAEPRSFKMTSLDKMDGSMPSEMESSRNDAKDDLGNLNVPDSSLPAENEAT 689
Query: 657 GPGFVPPPLAPIRGLLFPVDTRGPFIRRGPPFPPPPPGTVFGASPDYFSPRDVPGPPRAP 716
GPGF+PPPLAP+RG LFPVDTRGPF+RRGPPFPPPPPGT+FGAS YF PRD PGPP AP
Sbjct: 690 GPGFIPPPLAPVRGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRDFPGPPHAP 749
Query: 717 FAMRNVYLPRGFLPYRPPRPAFFP 740
FAMRN+Y PRG PY PRP F+P
Sbjct: 750 FAMRNIYPPRGLPPYFHPRPGFYP 773
>gi|224586773 hypothetical protein LOC643854 [Homo sapiens]
Length = 777
Score = 1137 bits (2942), Expect = 0.0
Identities = 585/749 (78%), Positives = 636/749 (84%), Gaps = 5/749 (0%)
Query: 1 MRPDSHPYGFPWELVIRAAVAGFFAVL-FLWRSFRSVTSRLYVRREKKFAVALSGLIEEK 59
MRPD +PYGFP ELV+ AAV GFF VL FLWRSFRSV SRLYV RE+K LSGLIEEK
Sbjct: 30 MRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGATLSGLIEEK 89
Query: 60 CKLLEKFSLVQKEYEGYEVESSLKNASFEKEATE-AQSLEATCEKLNRFNSELVHEILCL 118
CKLLEKFSL+QKEYEGYEVESSL++ASFEK A E A+SLEATCEKL+R NSEL EILCL
Sbjct: 90 CKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELEDEILCL 149
Query: 119 EKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEI 178
EK+LKEEKSKHS+Q+ELMADISK IQSLEDESKSLKSQ+AEAK+ K F+ +EER I I
Sbjct: 150 EKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAI 209
Query: 179 QDAWKENSELQESQKQLLQ-EAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTL 237
+DA ENS+LQ S KQL Q EAEVWK QVSEL KQK TFEDSKVHAEQVLNDKENHIKTL
Sbjct: 210 KDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTL 269
Query: 238 TERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLK 297
T L MKD A+LEED TDDDNLEL++NS+ E+GA LD+PPKGALKKLIHAAKLN SLK
Sbjct: 270 TGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLK 329
Query: 298 TLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTE 357
+LEGERN I IQLSEVDKTKEELTEHIKNLQT+QASLQSEN +FESENQKLQQKLK+MTE
Sbjct: 330 SLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTE 389
Query: 358 LYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKE-FEKTIH 416
YQENEMKLYRKL VEE R+E+EEKLS+V+E ISHATEELETYRK AKDL+E E+T+H
Sbjct: 390 FYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVH 449
Query: 417 FYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDV 476
FYQK++I +EK+ HDNW AA TAERNL+DLRKENAHN+QKLTE E K +LLEKDP LDV
Sbjct: 450 FYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFELLEKDPNALDV 509
Query: 477 PNTAFGRQHSPYGPSPLGWPSSETRASLYPPTLLEGPLRLSPLLPRGGGRGSRGPGNPPD 536
NTAFGR+HSP PSPLG PSSETRA P TLLE PLRLSP+LP GGGRG PGNP D
Sbjct: 510 SNTAFGREHSPCSPSPLGRPSSETRAFPSPQTLLEDPLRLSPVLPGGGGRGPSSPGNPLD 569
Query: 537 HQITKERGESSCDRLTDPHRAPSDAGPLAPPWEQDYRMMFPPPGQSYPDSALPPQRQDRF 596
HQIT ERGE S DRL DPHRAPSD G L+ P EQD RMMFPPPGQSYPDS LPPQR+DRF
Sbjct: 570 HQITNERGEPSYDRLIDPHRAPSDTGSLSSPVEQDRRMMFPPPGQSYPDSTLPPQREDRF 629
Query: 597 YSNCARLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDNLGNLKVPDSSLPAENEAT 656
YSN RLSGPAE RSF M SLDKMD SMPSEMESSRND KD+LGNL VPDSSLPAENEAT
Sbjct: 630 YSNSERLSGPAEPRSFKMTSLDKMDRSMPSEMESSRNDAKDDLGNLNVPDSSLPAENEAT 689
Query: 657 GPGFVPPPLAPIRGLLFPVDTRGPFIRRGPPFPPPPPGTVFGASPDYFSPRDVPGPPRAP 716
GPG +PPPLAPI G LFPVDTRGPF+RRGPPFPPPPPGT+FGAS YF PRD PGPP AP
Sbjct: 690 GPGLIPPPLAPISGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRDFPGPPHAP 749
Query: 717 FAMRNVYLPRGFLPYRPPRPAFFPPAPTF 745
FAMRN+Y PRG PY PRP F+ P PTF
Sbjct: 750 FAMRNIYPPRGLPPYLHPRPGFY-PNPTF 777
>gi|193290160 CTAGE family, member 4 [Homo sapiens]
Length = 777
Score = 1131 bits (2925), Expect = 0.0
Identities = 583/749 (77%), Positives = 633/749 (84%), Gaps = 5/749 (0%)
Query: 1 MRPDSHPYGFPWELVIRAAVAGFFAVL-FLWRSFRSVTSRLYVRREKKFAVALSGLIEEK 59
MRPD +PYGFP ELV+ AAV GFF VL FLWRSFRSV SRLYV RE+K LSGLIEEK
Sbjct: 30 MRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGATLSGLIEEK 89
Query: 60 CKLLEKFSLVQKEYEGYEVESSLKNASFEKEATE-AQSLEATCEKLNRFNSELVHEILCL 118
CKLLEKFSL+QKEYEGYEVESSL++ASFEK A E A+SLEATCEKLNR NSEL EILCL
Sbjct: 90 CKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDEILCL 149
Query: 119 EKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEI 178
EK+LKEEKSKHS+Q+ELMADISK IQSLEDESKSLKSQ+AEAK+ K F+ +EER I I
Sbjct: 150 EKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAI 209
Query: 179 QDAWKENSELQESQKQLLQ-EAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTL 237
+DA ENS+LQ S KQL Q EAEVWK +VSEL KQK TFEDSKVHAEQVLNDKENHIKTL
Sbjct: 210 KDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTL 269
Query: 238 TERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLK 297
T L MKD A+LEED TDDDNLELE+NS+ E+GA LD+P KGALKKLIHAAKLN SLK
Sbjct: 270 TGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLK 329
Query: 298 TLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTE 357
+LEGERN I IQLSEVDKTKEELTEHIKNLQT+QASLQSEN +FESENQKLQQKLK+MTE
Sbjct: 330 SLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTE 389
Query: 358 LYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKE-FEKTIH 416
YQENEMKLYRKL VEE R+E+EEKLS+V+E IS ATE LETYRK AKDL+E E+T+H
Sbjct: 390 FYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISRATEGLETYRKLAKDLEEELERTVH 449
Query: 417 FYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDV 476
FYQK++I +EK+ HDNW AA TAERNL+DLRKENAHN+QKLTE E K +LLEKDP LDV
Sbjct: 450 FYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNALDV 509
Query: 477 PNTAFGRQHSPYGPSPLGWPSSETRASLYPPTLLEGPLRLSPLLPRGGGRGSRGPGNPPD 536
NTAFGR+HSP PSPLG PSSETRA P TLLE PLRLSP+LP GGGRG PGNP D
Sbjct: 510 SNTAFGREHSPCSPSPLGRPSSETRAFPSPQTLLEDPLRLSPVLPGGGGRGPSSPGNPLD 569
Query: 537 HQITKERGESSCDRLTDPHRAPSDAGPLAPPWEQDYRMMFPPPGQSYPDSALPPQRQDRF 596
HQIT ERGE S DRL DPHRAPSD G L+ P EQD RMMFPPPGQSYPDS LPPQR+DRF
Sbjct: 570 HQITNERGEPSYDRLIDPHRAPSDTGSLSSPVEQDRRMMFPPPGQSYPDSTLPPQREDRF 629
Query: 597 YSNCARLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDNLGNLKVPDSSLPAENEAT 656
YSN RLSGPAE RSF M SLDKMD SMPSEMESSRND KD+LGNL VPDSSLPAENEAT
Sbjct: 630 YSNSERLSGPAEPRSFKMTSLDKMDRSMPSEMESSRNDAKDDLGNLNVPDSSLPAENEAT 689
Query: 657 GPGFVPPPLAPIRGLLFPVDTRGPFIRRGPPFPPPPPGTVFGASPDYFSPRDVPGPPRAP 716
GPG +PPPLAPI G LFPVDTRGPF+RRGPPFPPPPPGT+FGAS YF PRD PGPP AP
Sbjct: 690 GPGLIPPPLAPISGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRDFPGPPHAP 749
Query: 717 FAMRNVYLPRGFLPYRPPRPAFFPPAPTF 745
FAMRN+Y PRG PY PRP F+ P PTF
Sbjct: 750 FAMRNIYPPRGLPPYLHPRPGFY-PNPTF 777
>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
sapiens]
Length = 1907
Score = 226 bits (576), Expect = 6e-59
Identities = 193/727 (26%), Positives = 333/727 (45%), Gaps = 55/727 (7%)
Query: 1 MRPDSHPYGFPWELVIRAAVAGFFA-VLFLWRSFRSVTSRLYVRREKKFAVALSGLIEEK 59
++P YG PW+ V A G + +FLWR+ V R+Y E++ + L +++E
Sbjct: 1168 VQPGPDFYGLPWKPVFITAFLGIASFAIFLWRTVLVVKDRVYQVTEQQISEKLKTIMKEN 1227
Query: 60 CKLLEKFSLVQ---KEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEIL 116
+L++K S + KE + + E+ +N EA + + T EK N E++ +
Sbjct: 1228 TELVQKLSNYEQKIKESKKHVQETRKQNMILSDEAIKYKDKIKTLEK----NQEILDDTA 1283
Query: 117 C-LEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLE 175
L L+ E+ ++ + +L+++ K I+ L+D S+ +E ++ + +EE+++
Sbjct: 1284 KNLRVMLESEREQNVKNQDLISENKKSIEKLKDVISMNASEFSEVQIALNEAKLSEEKVK 1343
Query: 176 IEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIK 235
E +EN+ L++ ++QL QE E W + +EL +Q ++FE S+ E L K+++I
Sbjct: 1344 SECHRVQEENARLKKKKEQLQQEIEDWSKLHAELSEQIKSFEKSQKDLEVALTHKDDNIN 1403
Query: 236 TLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNAS 295
LT + ++ E + + + + + E G + K +K+++ ++ +
Sbjct: 1404 ALTNCITQLNLLECESESEGQNKGGNDSDELANGEVGGDRNEKMKNQIKQMMDVSRTQTA 1463
Query: 296 LKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVM 355
+ +E + + ++L TK L + +K L+ ++ SLQ+ E E + L+QK++++
Sbjct: 1464 ISVVEEDLKLLQLKLRASVSTKCNLEDQVKKLEDDRNSLQAAKAGLEDECKTLRQKVEIL 1523
Query: 356 TELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLK-EFEKT 414
ELYQ+ EM L +KL EE R E+E +LS DE A EE++TY++R ++++ E +KT
Sbjct: 1524 NELYQQKEMALQKKLSQEEYERQEREHRLSAADEKAVSAAEEVKTYKRRIEEMEDELQKT 1583
Query: 415 IHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGL 474
++ +I HEKKAH+NW A AER + + ++E A+ R KL E+ K+ +L+++P +
Sbjct: 1584 ERSFKNQIATHEKKAHENWLKARAAERAIAEEKREAANLRHKLLELTQKMAMLQEEPVIV 1643
Query: 475 ----DVPNTAFGRQHSPYGPSPLGWPSSETRASLYPPTLLEGPLR-LSPLL--------- 520
PNT + P + PS + PP +E P+R LS L
Sbjct: 1644 KPMPGKPNTQNPPRRGPLSQNGSFGPSPVSGGECSPPLTVEPPVRPLSATLNRRDMPRSE 1703
Query: 521 ----------PRGGGRGSRGPGNPPDHQITKERGESSCDRLTDPHRAPSDA----GPLAP 566
PR S G +P D +S R + P R + P P
Sbjct: 1704 FGSVDGPLPHPRWSAEAS-GKPSPSDPGSGTATMMNSSSRGSSPTRVLDEGKVNMAPKGP 1762
Query: 567 PWEQDYRMMFPPPGQSYPDSALPPQRQDRFYSNCARLSGPAELRSFNMPSLDKMDGSMPS 626
P +M P G P PP R Y +L GP R P M P
Sbjct: 1763 PPFPGVPLMSTPMGGPVP----PPIR----YGPPPQLCGPFGPRPLPPPFGPGM--RPPL 1812
Query: 627 EMESSRNDTKDNLGNLKV-PDSSLPAENEATGPGFVPPPLAPIRGLLFPVDTRGPFIRRG 685
+ +L + P LP G + P I G P T GP
Sbjct: 1813 GLREFAPGVPPGRRDLPLHPRGFLPGHAPFRPLGSLGPREYFIPGTRLPPPTHGP----- 1867
Query: 686 PPFPPPP 692
+PPPP
Sbjct: 1868 QEYPPPP 1874
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 83.2 bits (204), Expect = 8e-16
Identities = 85/462 (18%), Positives = 205/462 (44%), Gaps = 61/462 (13%)
Query: 55 LIEEKCKLLEKFSLVQKEYEGY-----EVESSLKNASFEKEATEAQSLEATCEKLNRFNS 109
L ++ +L EK L + E E++ L+ A F + +L+ E++ R
Sbjct: 185 LKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ---EEMWRQEE 241
Query: 110 ELVHEILCLEKE----------LKEEKSKHSEQNELMADISKRIQSLEDE---------- 149
EL + + K+ L+E++ K EQ E M KR++ E E
Sbjct: 242 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE 301
Query: 150 SKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLL--------QEAEV 201
K L+ Q + + ++ EE++ + + W++ L E +KQ+ QE +
Sbjct: 302 QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM 361
Query: 202 W------KEQVSELIKQKRTFE-DSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEED 254
W +E+ + +Q++ +E + K+ E+ + ++E ++ E + + ++ + EE+
Sbjct: 362 WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 421
Query: 255 VTDDDNLELEMN--SESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSE 312
+ + + E + E ++ + + +K+ + + + G+ +++ Q +
Sbjct: 422 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ-EK 480
Query: 313 VDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTE----LYQENEMKLYR 368
+ + ++++ E + ++ ++ + + ++++L++K + M E QE +M+ +
Sbjct: 481 MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEK 540
Query: 369 KLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFYQKKIILHEKK 428
K +EK ++EEK+ E E R+R K ++E E+ + ++K+ E+K
Sbjct: 541 KTQEQEKKTWDQEEKM-----------REEERMREREKKMREEEEMMREQEEKMQEQEEK 589
Query: 429 AHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKD 470
+ W E + + ++ +K+ E E + K+ E++
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQE 631
Score = 72.8 bits (177), Expect = 1e-12
Identities = 100/544 (18%), Positives = 228/544 (41%), Gaps = 66/544 (12%)
Query: 43 RREKKFAVALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCE 102
R+EK+ L E++ +L E+ L ++E + E E EK + + + E
Sbjct: 280 RQEKRLREQEKELREQEKELREQKKLREQEEQMQEQE--------EKMWEQEEKMREQEE 331
Query: 103 KLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLED-------------- 148
K+ R L + EK+++E++ K +Q E M + +R++ E+
Sbjct: 332 KMWRQEERLWEQ----EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEK 387
Query: 149 --ESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQV 206
E + ++ + + + + + EE+++ + ++ W++ + + Q+ Q+ ++W+++
Sbjct: 388 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 447
Query: 207 SELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDD----NLE 262
+ ++K ++ K+ ++ + +E + E++ + +D + EE + D + + E
Sbjct: 448 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWR-QEKMREQEDQMWEQEEKMRDQEQKMWDQE 506
Query: 263 LEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTE 322
M + E + + K K+ KT E E+ E + +E + E
Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW--DQEEKMREEERMRE 564
Query: 323 HIKNLQTEQASLQSENTHFESENQKL---QQKLKVMTELYQENEMKLYR----------- 368
K ++ E+ ++ + + + +K+ ++K+ E QE E K++
Sbjct: 565 REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE 624
Query: 369 -KLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFYQKKIILHEK 427
K+ +E+ E+EEK+ + +E + E+ E R++ + ++E E+ + ++K+ E+
Sbjct: 625 DKMQEQEEMMWEQEEKMQEQEEKM---WEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681
Query: 428 KAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDVPNTAFGRQHSP 487
K E + + ++ +K+ E K+ E+ +G + R
Sbjct: 682 KMQGQ-------EEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQ 734
Query: 488 YGPSPLGWPSSETRAS---LYPPTLLEGPLRLSPLLPRGGGRGSRGPGNPPDHQITKERG 544
P E R S L P +L + P G G G G+P D+ +E
Sbjct: 735 KEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAG---GEAGEGSPQDNPTAQEIM 791
Query: 545 ESSC 548
+ C
Sbjct: 792 QLFC 795
Score = 62.8 bits (151), Expect = 1e-09
Identities = 66/322 (20%), Positives = 144/322 (44%), Gaps = 27/322 (8%)
Query: 143 IQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVW 202
I+ L E +L ++ +T + + L+ +++ A E SE+Q + K+L ++ E
Sbjct: 161 IEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERA 220
Query: 203 KEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLE 262
K + ++ Q T ++ E+ L ++E I+ E++ + ++ L E E
Sbjct: 221 KFLLPQV--QTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEE---RLREQ-------E 268
Query: 263 LEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTE 322
+M + E + + K+L K K L + Q+ Q ++ + +E++ E
Sbjct: 269 GKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMRE 328
Query: 323 HIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEE 382
+ + ++ L + + QK++ + + M E Q+ ++ + + E++ E+EE
Sbjct: 329 QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE--QDERLREKEERMREQEKMWEQEE 386
Query: 383 KLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFYQKKIILHEKKAHDNWSAAWTAERN 442
K+ +E E R+R K ++E E+T+ ++K+ E+ + W +R
Sbjct: 387 KM-----------QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 435
Query: 443 LNDLRKENAHNRQKLTEIEFKI 464
+KE ++K+ E E KI
Sbjct: 436 PE--QKEKLWEQEKMQEQEEKI 455
Score = 50.1 bits (118), Expect = 8e-06
Identities = 45/197 (22%), Positives = 90/197 (45%), Gaps = 18/197 (9%)
Query: 291 KLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQ 350
K + ++ L ER+ + ++L T EEL + LQ + +SE + + ++L++
Sbjct: 156 KADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKR 215
Query: 351 KL--------KVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMI----SHATEEL 398
KL +V T QE + +L +EK ++EEK+ + +E + E+
Sbjct: 216 KLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQE 275
Query: 399 ETYRKRAKDLKEFEKTIHFY------QKKIILHEKKAHDNWSAAWTAERNLNDLRKENAH 452
E R++ K L+E EK + QKK+ E++ + W E + + ++
Sbjct: 276 EKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWR 335
Query: 453 NRQKLTEIEFKIKLLEK 469
++L E E +++ E+
Sbjct: 336 QEERLWEQEKQMREQEQ 352
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 82.4 bits (202), Expect = 1e-15
Identities = 94/473 (19%), Positives = 198/473 (41%), Gaps = 71/473 (15%)
Query: 24 FAVLFLWRSFRSVTSRLYVRREKKFAVALSGLIEEK--CKLLEKFSLVQKEY---EGYEV 78
F + + RSF +V +++ K L EK + E+F ++ E E
Sbjct: 818 FCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRK 877
Query: 79 ESSLKNASFEKEATEAQ-SLEATCEKLNRFNS---ELVHEILCLEKELKEEKSKHSEQNE 134
E K + KE + Q ++A E L +L+ + LE ++KE + ++ E
Sbjct: 878 ELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEE 937
Query: 135 LMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQ 194
+ A+++ + + LEDE LK + + ++T + + KE + K
Sbjct: 938 INAELTAKKRKLEDECSELKKDIDDLELTLAKVE--------------KEKHATENKVKN 983
Query: 195 LLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEED 254
L +E E +++L K+K+ +++ L +E+ + TLT+ +K++ V LE
Sbjct: 984 LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGS 1043
Query: 255 VTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVD 314
+ + L ++ L + + LEG+ + +++
Sbjct: 1044 LEQEKKLRMD---------------------------LERAKRKLEGDLKLAQESIMDIE 1076
Query: 315 KTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVE- 373
K++L E +K + E ++LQS+ ++ +LQ+K+K + +E E ++ +
Sbjct: 1077 NEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRA 1136
Query: 374 --EKCRLEKEEKLSKVDEMISHA----TEELETYRKRAKDLKEFEKTIHFYQKKIILHE- 426
EK R + +L ++ E + A + ++E +KR EF+K ++ + HE
Sbjct: 1137 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKRE---AEFQKMRRDLEEATLQHEA 1193
Query: 427 -----KKAHDNWSAAW-----TAERNLNDLRKENAHNRQKLTEIEFKIKLLEK 469
+K H + A +R L KE + + ++ ++ ++ + K
Sbjct: 1194 TAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSK 1246
Score = 67.0 bits (162), Expect = 6e-11
Identities = 85/434 (19%), Positives = 181/434 (41%), Gaps = 23/434 (5%)
Query: 51 ALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKE-ATEAQSLEATCEKLNRFNS 109
A S IE K +F ++++ E ++ A+ K+ A L + L R
Sbjct: 1162 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ 1221
Query: 110 ELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQA 169
+L E ++ E+ + S ++ ++ K ++LED+ LKS+ E + A
Sbjct: 1222 KLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTA 1281
Query: 170 NEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLND 229
RL+ E + ++ E + QL + + + +Q+ EL +Q +K L
Sbjct: 1282 QRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQS 1341
Query: 230 KENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHA 289
+ L E+ + ++ A L+ ++ + + ++ E A KK
Sbjct: 1342 SRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKK---- 1397
Query: 290 AKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQ 349
KL L+ E + + + ++KTK+ L +++L + ++ N + ++K +
Sbjct: 1398 -KLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD---VERTNAACAALDKKQR 1453
Query: 350 QKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLK 409
K++ E Q+ E + + +L +K +L K+ + ++LET ++ K+L+
Sbjct: 1454 NFDKILAEWKQKCE-ETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQ 1512
Query: 410 -----------EFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLT 458
E K IH +K E++ + +A AE +L + + +L
Sbjct: 1513 QEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELN 1572
Query: 459 EIEFKI--KLLEKD 470
+++ ++ K+ EKD
Sbjct: 1573 QVKSEVDRKIAEKD 1586
Score = 52.4 bits (124), Expect = 2e-06
Identities = 60/335 (17%), Positives = 133/335 (39%), Gaps = 33/335 (9%)
Query: 88 EKEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLE 147
+K + +E NR +E + + LK+ + + D+ +++ +E
Sbjct: 1622 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVE 1681
Query: 148 DESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVS 207
+ L++++ E + T ++ + + + E E+ DA + QLL Q +
Sbjct: 1682 RRANLLQAEIEELRATLEQTERSRKIAEQELLDA--------SERVQLLH------TQNT 1727
Query: 208 ELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNS 267
LI K+ E + + D + E+ K AM+ E E+
Sbjct: 1728 SLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAE----------ELKK 1777
Query: 268 ESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNL 327
E + A+L+ +KK + + L+ E E+ + L K ++L ++ L
Sbjct: 1778 EQDTSAHLER-----MKKNMEQTVKDLQLRLDEAEQ----LALKGGKKQIQKLEARVREL 1828
Query: 328 QTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKV 387
+ E S Q N +K ++++K +T +E+ + R + +K + + + +
Sbjct: 1829 EGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQA 1888
Query: 388 DEMISHATEELETYRKRAKDLKEFEKTIHFYQKKI 422
+E + L +RK +L+E E+ + ++
Sbjct: 1889 EEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV 1923
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 82.4 bits (202), Expect = 1e-15
Identities = 94/473 (19%), Positives = 198/473 (41%), Gaps = 71/473 (15%)
Query: 24 FAVLFLWRSFRSVTSRLYVRREKKFAVALSGLIEEK--CKLLEKFSLVQKEY---EGYEV 78
F + + RSF +V +++ K L EK + E+F ++ E E
Sbjct: 818 FCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRK 877
Query: 79 ESSLKNASFEKEATEAQ-SLEATCEKLNRFNS---ELVHEILCLEKELKEEKSKHSEQNE 134
E K + KE + Q ++A E L +L+ + LE ++KE + ++ E
Sbjct: 878 ELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEE 937
Query: 135 LMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQ 194
+ A+++ + + LEDE LK + + ++T + + KE + K
Sbjct: 938 INAELTAKKRKLEDECSELKKDIDDLELTLAKVE--------------KEKHATENKVKN 983
Query: 195 LLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEED 254
L +E E +++L K+K+ +++ L +E+ + TLT+ +K++ V LE
Sbjct: 984 LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGS 1043
Query: 255 VTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVD 314
+ + L ++ L + + LEG+ + +++
Sbjct: 1044 LEQEKKLRMD---------------------------LERAKRKLEGDLKLAQESIMDIE 1076
Query: 315 KTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVE- 373
K++L E +K + E ++LQS+ ++ +LQ+K+K + +E E ++ +
Sbjct: 1077 NEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRA 1136
Query: 374 --EKCRLEKEEKLSKVDEMISHA----TEELETYRKRAKDLKEFEKTIHFYQKKIILHE- 426
EK R + +L ++ E + A + ++E +KR EF+K ++ + HE
Sbjct: 1137 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKRE---AEFQKMRRDLEEATLQHEA 1193
Query: 427 -----KKAHDNWSAAW-----TAERNLNDLRKENAHNRQKLTEIEFKIKLLEK 469
+K H + A +R L KE + + ++ ++ ++ + K
Sbjct: 1194 TAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSK 1246
Score = 67.0 bits (162), Expect = 6e-11
Identities = 85/434 (19%), Positives = 181/434 (41%), Gaps = 23/434 (5%)
Query: 51 ALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKE-ATEAQSLEATCEKLNRFNS 109
A S IE K +F ++++ E ++ A+ K+ A L + L R
Sbjct: 1162 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ 1221
Query: 110 ELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQA 169
+L E ++ E+ + S ++ ++ K ++LED+ LKS+ E + A
Sbjct: 1222 KLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTA 1281
Query: 170 NEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLND 229
RL+ E + ++ E + QL + + + +Q+ EL +Q +K L
Sbjct: 1282 QRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQS 1341
Query: 230 KENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHA 289
+ L E+ + ++ A L+ ++ + + ++ E A KK
Sbjct: 1342 SRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKK---- 1397
Query: 290 AKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQ 349
KL L+ E + + + ++KTK+ L +++L + ++ N + ++K +
Sbjct: 1398 -KLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD---VERTNAACAALDKKQR 1453
Query: 350 QKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLK 409
K++ E Q+ E + + +L +K +L K+ + ++LET ++ K+L+
Sbjct: 1454 NFDKILAEWKQKCE-ETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQ 1512
Query: 410 -----------EFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLT 458
E K IH +K E++ + +A AE +L + + +L
Sbjct: 1513 QEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELN 1572
Query: 459 EIEFKI--KLLEKD 470
+++ ++ K+ EKD
Sbjct: 1573 QVKSEVDRKIAEKD 1586
Score = 52.4 bits (124), Expect = 2e-06
Identities = 60/335 (17%), Positives = 133/335 (39%), Gaps = 33/335 (9%)
Query: 88 EKEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLE 147
+K + +E NR +E + + LK+ + + D+ +++ +E
Sbjct: 1622 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVE 1681
Query: 148 DESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVS 207
+ L++++ E + T ++ + + + E E+ DA + QLL Q +
Sbjct: 1682 RRANLLQAEIEELRATLEQTERSRKIAEQELLDA--------SERVQLLH------TQNT 1727
Query: 208 ELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNS 267
LI K+ E + + D + E+ K AM+ E E+
Sbjct: 1728 SLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAE----------ELKK 1777
Query: 268 ESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNL 327
E + A+L+ +KK + + L+ E E+ + L K ++L ++ L
Sbjct: 1778 EQDTSAHLER-----MKKNMEQTVKDLQLRLDEAEQ----LALKGGKKQIQKLEARVREL 1828
Query: 328 QTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKV 387
+ E S Q N +K ++++K +T +E+ + R + +K + + + +
Sbjct: 1829 EGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQA 1888
Query: 388 DEMISHATEELETYRKRAKDLKEFEKTIHFYQKKI 422
+E + L +RK +L+E E+ + ++
Sbjct: 1889 EEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV 1923
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 82.0 bits (201), Expect = 2e-15
Identities = 85/427 (19%), Positives = 200/427 (46%), Gaps = 20/427 (4%)
Query: 51 ALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSE 110
ALS + +K K + KE + +E + E+ + L+ + + SE
Sbjct: 241 ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSE 300
Query: 111 LVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQAN 170
+ + L+++L+ K +Q +L A+ + L+ S L++QV E ++ + Q
Sbjct: 301 IQLNVKELKRKLERAKLLLPQQ-QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 359
Query: 171 EERL---EIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTF---EDSKVHAE 224
EE++ E +IQ+ W+E ++QE ++++ ++ E +EQ ++ +Q+ E+ E
Sbjct: 360 EEKMWRQEEKIQE-WEE--KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 416
Query: 225 QVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNL--ELEMNSESEDGAYLDNPPKGA 282
+++ +KE ++ E + + ++ + LEE + + + + + E E E + +
Sbjct: 417 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 476
Query: 283 LKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFE 342
K K+ + + + +++ Q ++ + +E++ E K + E+ Q E +
Sbjct: 477 AKMWRQEEKIREQEEKIREQEEKMWRQEEKIHE-QEKIREEEKRQEQEEMWRQEEKIREQ 535
Query: 343 SENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYR 402
E + ++K+ E ++ E K++R+ EEK ++EEK+ + +E + E++ R
Sbjct: 536 EEIWRQKEKIHEQEEKIRKQEEKMWRQ---EEKMH-DQEEKIREQEEKVWRQEEKI---R 588
Query: 403 KRAKDLKEFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEF 462
++ + ++E E+ I ++ E+K + E + + ++ +K+ E E
Sbjct: 589 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEK 648
Query: 463 KIKLLEK 469
KI+ E+
Sbjct: 649 KIREQEE 655
Score = 72.8 bits (177), Expect = 1e-12
Identities = 72/371 (19%), Positives = 155/371 (41%), Gaps = 54/371 (14%)
Query: 124 EEKSKHSEQNELMADISKRIQS---LEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQD 180
E+K+ H Q L ++ ++ + L + L+ + ++ K+ + L + D
Sbjct: 171 EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHD 230
Query: 181 AWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTER 240
+WK EL+++ + + + + EL K++ E + T+T+
Sbjct: 231 SWKFAGELEQALSAVATQKKKADRYIEELTKERDAL------------SLELYRNTITDE 278
Query: 241 LLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLE 300
LK K+ + + + + E+++N + LK+ + AKL + L+
Sbjct: 279 ELKEKNAKLQEKLQLVESEKSEIQLNVKE-------------LKRKLERAKLLLPQQQLQ 325
Query: 301 GERNQIYIQLSEVDK------TKEELTEHIKNLQTEQASLQSEN-THFESENQKLQQKLK 353
E + + +L V + EL + Q E+ Q E +E + Q+ ++K++
Sbjct: 326 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 385
Query: 354 VMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEEL----ETYRKRAKDLK 409
E +E E K+ R +E+ EKEEK+ + +EM+ E++ E ++ + ++
Sbjct: 386 EQEEKIREQEEKMRR----QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 441
Query: 410 EFEKTIHFYQK-----------KIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLT 458
E E+ +H +K + I ++K + + W E + + ++ +K+
Sbjct: 442 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMW 501
Query: 459 EIEFKIKLLEK 469
E KI EK
Sbjct: 502 RQEEKIHEQEK 512
Score = 69.7 bits (169), Expect = 9e-12
Identities = 76/390 (19%), Positives = 173/390 (44%), Gaps = 30/390 (7%)
Query: 29 LWRSFRSVTSRLYVRREKKFAVALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFE 88
LW R+E+K + E++ K+ E+ ++++ E + + E
Sbjct: 351 LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 410
Query: 89 KEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLED 148
K + + + EK+ R E++ E E++++E + K EQ ++ KR Q E
Sbjct: 411 KMRRQEEMMWEKEEKMRR-QEEMMWE---KEEKIRELEEKMHEQEKIREQEEKR-QEEEK 465
Query: 149 ESKSLKSQVAEAKM--TFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQV 206
+ K Q EAKM ++ + EE++ + + W++ ++ E +K ++E E +EQ
Sbjct: 466 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEK--IREEEKRQEQ- 522
Query: 207 SELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMN 266
E+ +Q+ + E++ KE I E++ K ++ + EE + D + E
Sbjct: 523 EEMWRQEEKIREQ----EEIWRQKEK-IHEQEEKIRKQEEKMWRQEEKMHDQE----EKI 573
Query: 267 SESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKN 326
E E+ + K K+ + + + Q ++ + +E++ E +
Sbjct: 574 REQEEKVWRQEE-----KIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 628
Query: 327 LQTEQASLQSENTHFESENQKL---QQKLKVMTELYQENEMKLYR---KLIVEEKCRLEK 380
+Q ++ ++ + + +K+ ++K++ E+ QE E K++ K+ +E+ E+
Sbjct: 629 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 688
Query: 381 EEKLSKVDEMISHATEELETYRKRAKDLKE 410
EEK+ + +E + L ++ ++ +E
Sbjct: 689 EEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 49.3 bits (116), Expect = 1e-05
Identities = 44/278 (15%), Positives = 125/278 (44%), Gaps = 19/278 (6%)
Query: 57 EEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEIL 116
EEK + EK +E E + + + EK + + + EK+ R ++ +
Sbjct: 457 EEKRQEEEKI----REQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEK 512
Query: 117 CLEKELKEEKSKHSEQNELMAD---ISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEER 173
E+E ++E+ + Q E + + I ++ + + ++ + ++ Q + ++ EE+
Sbjct: 513 IREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEK 572
Query: 174 LEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTF---EDSKVHAEQVLNDK 230
+ + + W++ +++E ++++ ++ E +EQ +Q+ E+ E+ + ++
Sbjct: 573 IREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 632
Query: 231 ENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAA 290
E ++ E++ + + + EE + + + EM E E+ + K
Sbjct: 633 EEKMRRQEEKIREQEKKIREQEEKIREQE----EMMQEQEEKMWEQEE-----KMCEQEE 683
Query: 291 KLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ 328
K+ + + + +++ Q + + +E++ EH ++L+
Sbjct: 684 KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 81.6 bits (200), Expect = 2e-15
Identities = 88/435 (20%), Positives = 200/435 (45%), Gaps = 37/435 (8%)
Query: 51 ALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSE 110
ALS + +K K + KE + +E + E+ + L+ + + SE
Sbjct: 180 ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSE 239
Query: 111 LVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQAN 170
+ + L+++L+ K +Q +L A+ + L+ S L++QV E ++ + Q
Sbjct: 240 IQLNVKELKRKLERAKLLLPQQ-QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 298
Query: 171 EERL---EIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTF----------- 216
EE++ E +IQ+ W+E ++QE ++++ ++ E +EQ ++ +Q+
Sbjct: 299 EEKMWRQEEKIQE-WEE--KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 355
Query: 217 ------EDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNL--ELEMNSE 268
E+ E+++ +KE ++ E + + ++ + LEE + + + + + E E
Sbjct: 356 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 415
Query: 269 SEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ 328
E + + K K+ + + + +++ Q ++ + +E++ E K +
Sbjct: 416 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE-QEKIREEEKRQE 474
Query: 329 TEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVD 388
E+ Q E H + E + ++K+ E ++ E K++R+ EEK R E+EEK+ + +
Sbjct: 475 QEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ---EEKIR-EQEEKIREQE 530
Query: 389 EMISHATEELETYRKRAKDLKEFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRK 448
E + E++ R++ + +E EK ++++ I E+K + W E + + +
Sbjct: 531 EKMWRQEEKI---REQEEMWREEEK---MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEE 584
Query: 449 ENAHNRQKLTEIEFK 463
+ +K+ E E K
Sbjct: 585 KVWRQEEKIREQEEK 599
Score = 76.3 bits (186), Expect = 1e-13
Identities = 85/470 (18%), Positives = 213/470 (45%), Gaps = 43/470 (9%)
Query: 29 LWRSFRSVTSRLYVRREKKFAVALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFE 88
LW R+E+K + E++ K+ E+ ++++ E + + +E
Sbjct: 290 LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM---WE 346
Query: 89 KEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLED 148
KE + E EK + + E+ + E++ K Q E+M + ++I+ LE+
Sbjct: 347 KEEKMRRQEEMMWEKEEKMRRQ--------EEMMWEKEEKMRRQEEMMWEKEEKIRELEE 398
Query: 149 ---ESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLL-QEAEVWK- 203
E + ++ Q E + ++ + E+R E E + W++ +++E ++++ QE ++W+
Sbjct: 399 KMHEQEKIREQ-EEKRQEEEKIREQEKRQEQEAK-MWRQEEKIREQEEKIREQEKKMWRQ 456
Query: 204 -------EQVSELIKQKRTFE----DSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLE 252
E++ E K++ E + K+H ++ + ++ + E++ K ++ V E
Sbjct: 457 EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE 516
Query: 253 EDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSE 312
E + + + ++ + E + + + K++ K E E+ Q Q +
Sbjct: 517 EKIREQEE---KIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQE--QEDK 571
Query: 313 VDKTKEELTEHIKNLQTEQASLQSENTHFESENQKL---QQKLKVMTELYQENEMKLYR- 368
+ + +E++ E + + ++ ++ + + + +K+ ++K++ E QE E K+
Sbjct: 572 MWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQ 631
Query: 369 --KLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFYQKKIILHE 426
K+ +E+ E+EEK+ + +E + E+++ ++ + + E+ I +KKI E
Sbjct: 632 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ---EQEETMWRQEEKIREQEKKIREQE 688
Query: 427 KKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDV 476
+K + E + + ++ +K+ E E K++ E+ + +V
Sbjct: 689 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Score = 70.5 bits (171), Expect = 5e-12
Identities = 73/381 (19%), Positives = 157/381 (41%), Gaps = 60/381 (15%)
Query: 124 EEKSKHSEQNELMADISKRIQS---LEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQD 180
E+K+ H Q L ++ ++ + L + L+ + ++ K+ + L + D
Sbjct: 110 EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHD 169
Query: 181 AWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTER 240
+WK EL+++ + + + + EL K++ E + T+T+
Sbjct: 170 SWKFAGELEQALSAVATQKKKADRYIEELTKERDAL------------SLELYRNTITDE 217
Query: 241 LLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLE 300
LK K+ + + + + E+++N + LK+ + AKL + L+
Sbjct: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKE-------------LKRKLERAKLLLPQQQLQ 264
Query: 301 GERNQIYIQLSEVDK------TKEELTEHIKNLQTEQASLQSEN-THFESENQKLQQKLK 353
E + + +L V + EL + Q E+ Q E +E + Q+ ++K++
Sbjct: 265 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324
Query: 354 VMTELYQENEMKLYR----------KLIVEEKCRLEKEEKLSKVDEMISHATEEL----E 399
E +E E K+ R K+ +E+ EKEEK+ + +EM+ E++ E
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 384
Query: 400 TYRKRAKDLKEFEKTIHFYQK-----------KIILHEKKAHDNWSAAWTAERNLNDLRK 448
++ + ++E E+ +H +K + I ++K + + W E + + +
Sbjct: 385 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 444
Query: 449 ENAHNRQKLTEIEFKIKLLEK 469
+ +K+ E KI EK
Sbjct: 445 KIREQEKKMWRQEEKIHEQEK 465
Score = 62.8 bits (151), Expect = 1e-09
Identities = 56/359 (15%), Positives = 161/359 (44%), Gaps = 32/359 (8%)
Query: 57 EEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEIL 116
+E+ K+ E+ ++E + + E ++ EK + + + EK++ E
Sbjct: 414 QEEEKIREQEKRQEQEAKMWRQEEKIREQE-EKIREQEKKMWRQEEKIHEQEKIREEEKR 472
Query: 117 CLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEI 176
++E+ ++ K EQ E+ ++ + + ++ + ++ Q + ++ + EE++
Sbjct: 473 QEQEEMWRQEEKIHEQEEIW----RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE 528
Query: 177 EIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKT 236
+ + W++ +++E + E+W+E +++ E K+ E+ ++E+ +
Sbjct: 529 QEEKMWRQEEKIREQE-------EMWRE-------EEKMHEQEKIWEEEKRQEQEDKMWR 574
Query: 237 LTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLI--HAAKLNA 294
E++ + ++ V EE + + + E E E+ + ++ I K+
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQE----EKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE 630
Query: 295 SLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKL---QQK 351
+ + + Q ++ + +E++ E + +Q ++ ++ + + +K+ ++K
Sbjct: 631 QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEK 690
Query: 352 LKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKE 410
++ E+ QE E K++ +E+ E+EEK+ + +E + E++ R + +E
Sbjct: 691 IREQEEMMQEQEEKMWE----QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 745
Score = 44.3 bits (103), Expect = 4e-04
Identities = 30/209 (14%), Positives = 95/209 (45%), Gaps = 8/209 (3%)
Query: 29 LWRSFRSVTSRLYVRREKKFAVALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFE 88
+WR + + + E+K + ++ K+ E+ V ++ E + + E
Sbjct: 546 MWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE 605
Query: 89 KEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRI----Q 144
K + + + EK+ ++ + E++++E++ EQ E M + +++ +
Sbjct: 606 KMWKQEEKIREQEEKIQEQEEKIREQ----EEKIREQEEMTQEQEEKMGEQEEKMCEQEE 661
Query: 145 SLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKE 204
++++ +++ Q + + K+ + EE++ + + ++ ++ E ++++ ++ E +E
Sbjct: 662 KMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 721
Query: 205 QVSELIKQKRTFEDSKVHAEQVLNDKENH 233
Q ++ +Q+ + +V Q + H
Sbjct: 722 QEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 81.6 bits (200), Expect = 2e-15
Identities = 92/426 (21%), Positives = 180/426 (42%), Gaps = 68/426 (15%)
Query: 24 FAVLFLWRSFRSVTSRLYVRREKKFAVALSGLIEEK--CKLLEKFS-----LVQKEYEGY 76
F + + R+F +V +++ K L EK + E+F L + E +
Sbjct: 816 FCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRK 875
Query: 77 EVESSLKNASFEKE------ATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHS 130
E+E + EK EA SL E+ + +L+ + LE ++KE +
Sbjct: 876 ELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCD----QLIKTKIQLEAKIKEVTERAE 931
Query: 131 EQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQE 190
++ E+ A+++ + + LEDE LK + + ++T + + KE +
Sbjct: 932 DEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE--------------KEKHATEN 977
Query: 191 SQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAM 250
K L +E E +++L K+K+ +++ L +E+ + TLT+ +K
Sbjct: 978 KVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIK------- 1030
Query: 251 LEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQL 310
LE+ V D LE + E E +D L + + LEG+
Sbjct: 1031 LEQQVDD-----LEGSLEQEKKIRMD---------------LERAKRKLEGDLKLAQEST 1070
Query: 311 SEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKL 370
+++ K++L E +K + E + LQS+ ++ +LQ+K+K + +E E ++ +
Sbjct: 1071 MDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAER 1130
Query: 371 IVE---EKCRLEKEEKLSKVDEMISHA----TEELETYRKRAKDLKEFEKTIHFYQKKII 423
EK R + +L ++ E + A + ++E +KR EF+K ++ +
Sbjct: 1131 ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKRE---AEFQKMRRDLEEATL 1187
Query: 424 LHEKKA 429
HE A
Sbjct: 1188 QHEATA 1193
Score = 67.0 bits (162), Expect = 6e-11
Identities = 83/434 (19%), Positives = 181/434 (41%), Gaps = 23/434 (5%)
Query: 51 ALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKE-ATEAQSLEATCEKLNRFNS 109
A S IE K +F ++++ E ++ A+ K+ A L + L R
Sbjct: 1160 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ 1219
Query: 110 ELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQA 169
+L E ++ E+ + S ++ ++ K ++LED+ +K++ E + A
Sbjct: 1220 KLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTA 1279
Query: 170 NEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLND 229
RL+ E + ++ E QL + + + +Q+ EL +Q +K L
Sbjct: 1280 QRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQS 1339
Query: 230 KENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHA 289
+ L E+ + ++ A L+ ++ ++ + ++ E A KK
Sbjct: 1340 SRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKK---- 1395
Query: 290 AKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQ 349
KL L+ E + + + ++KTK+ L +++L + ++ N + ++K +
Sbjct: 1396 -KLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMID---VERTNAACAALDKKQR 1451
Query: 350 QKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLK 409
K++ E Q+ E + + +L +K +L K+ + ++LET ++ K+L+
Sbjct: 1452 NFDKILAEWKQKCE-ETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQ 1510
Query: 410 -----------EFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLT 458
E K IH +K E++ + +A AE +L + + +L
Sbjct: 1511 QEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELN 1570
Query: 459 EIEFKI--KLLEKD 470
+++ ++ K+ EKD
Sbjct: 1571 QVKSEVDRKIAEKD 1584
Score = 52.0 bits (123), Expect = 2e-06
Identities = 62/338 (18%), Positives = 132/338 (39%), Gaps = 39/338 (11%)
Query: 88 EKEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLE 147
+K + +E NR +E + + LK+ + + D+ +++ +E
Sbjct: 1620 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVE 1679
Query: 148 DESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVS 207
+ L++++ E + T ++ + + + E E+ DA + QLL Q +
Sbjct: 1680 RRANLLQAEIEELRATLEQTERSRKIAEQELLDA--------SERVQLLH------TQNT 1725
Query: 208 ELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNS 267
LI K+ E + + D + E+ K AM+ E E+
Sbjct: 1726 SLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAE----------ELKK 1775
Query: 268 ESEDGAYLDNPPKG---ALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHI 324
E + A+L+ K +K L H A L+G + QI ++L +
Sbjct: 1776 EQDTSAHLERMKKNLEQTVKDLQHRLD-EAEQLALKGGKKQI-----------QKLEARV 1823
Query: 325 KNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKL 384
+ L+ E S Q N +K ++K+K +T +E+ + R + +K + + +
Sbjct: 1824 RELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYK 1883
Query: 385 SKVDEMISHATEELETYRKRAKDLKEFEKTIHFYQKKI 422
+ +E + L +R+ +L+E E+ + ++
Sbjct: 1884 RQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQV 1921
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 81.3 bits (199), Expect = 3e-15
Identities = 97/431 (22%), Positives = 188/431 (43%), Gaps = 70/431 (16%)
Query: 57 EEKCKLLEKFSLVQKEYEGYEV---ESSLKNASFEKEATEAQSLEATCEKLNRFNSE--- 110
+E + E+F+ +++ E E E K S +E + Q L+ E+ N ++E
Sbjct: 847 KEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQ-LQVQAEQDNLADAEERC 905
Query: 111 --LVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQ 168
L+ + LE ++KE + ++ E+ A+++ + + LEDE LK + + ++T + +
Sbjct: 906 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVE 965
Query: 169 ANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLN 228
KE + K L +E E +++L K+K+ +++ A L
Sbjct: 966 --------------KEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQ 1011
Query: 229 DKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIH 288
+E+ + TLT+ +K LE+ V D LE + E E +D
Sbjct: 1012 AEEDKVNTLTKAKVK-------LEQQVDD-----LEGSLEQEKKVRMD------------ 1047
Query: 289 AAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKL 348
L + + LEG+ + +++ K++L E +K E +L + ++ +L
Sbjct: 1048 ---LERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 349 QQKLKVMTELYQENEMKLYRKLIVE---EKCRLEKEEKLSKVDEMISHA----TEELETY 401
Q+KLK + +E E +L + EK R + +L ++ E + A + ++E
Sbjct: 1105 QKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMN 1164
Query: 402 RKRAKDLKEFEKTIHFYQKKIILHE------KKAHDNWSAAWTAERNLNDLRKENAHNRQ 455
+KR EF+K ++ + HE +K H + S A E+ N R + ++
Sbjct: 1165 KKRE---AEFQKMRRDLEEATLQHEATAAALRKKHAD-SVAELGEQIDNLQRVKQKLEKE 1220
Query: 456 KLTEIEFKIKL 466
K EFK++L
Sbjct: 1221 K---SEFKLEL 1228
Score = 62.8 bits (151), Expect = 1e-09
Identities = 91/508 (17%), Positives = 195/508 (38%), Gaps = 100/508 (19%)
Query: 46 KKFAVALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLN 105
KK A +++ L E+ L ++KE +++E ++ E+ +LE C L
Sbjct: 1194 KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTL- 1252
Query: 106 RFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLE----------DESKSLKS 155
E ++ E +SK E + D++ + L+ DE ++L S
Sbjct: 1253 -------------EDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALIS 1299
Query: 156 QVAEAKMTF-KRFQANEERLEIEIQ--------------------DAWKENSELQESQKQ 194
Q+ K+T+ ++ + + +LE E++ + ++E +E + ++
Sbjct: 1300 QLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR 1359
Query: 195 LLQEAEV----WKEQV-SELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVA 249
+L +A W+ + ++ I++ E++K Q L + E ++ + + ++
Sbjct: 1360 VLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKH 1419
Query: 250 MLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIH----AAKLNASLKTLEGERNQ 305
L+ ++ D L +++ + A LD + K L + + L++ + E
Sbjct: 1420 RLQNEIED---LMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS 1476
Query: 306 IYIQLSEVDKTKEELTEHIKNLQTEQASLQSE---------------------NTHFESE 344
+ +L ++ EE EH++ + E +LQ E E+E
Sbjct: 1477 LSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAE 1536
Query: 345 NQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHA---------- 394
+LQ L+ + E K+ R + + + E E KL++ DE + A
Sbjct: 1537 KMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDS 1596
Query: 395 ------------TEELETYRKRAKDLKEFEKTIHFYQKKIILHEKKAHDNWSAAWTAERN 442
E L +K DL E E + + +K+ S +
Sbjct: 1597 LQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQ 1656
Query: 443 LNDLRKENAHNRQKLTEIEFKIKLLEKD 470
L+D + N ++ + +E + LL+ +
Sbjct: 1657 LDDAVRANDDLKENIAIVERRNNLLQAE 1684
Score = 54.7 bits (130), Expect = 3e-07
Identities = 91/463 (19%), Positives = 178/463 (38%), Gaps = 106/463 (22%)
Query: 41 YVRREKKFAVALSGLIEE---KCKLLEKFSLVQKEYEG--YEVESSLKNASFEKEATEAQ 95
+ R K +S L E+ K + + V+K+ E E++S+L+ A E E +
Sbjct: 1498 FKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGK 1557
Query: 96 SLEATCEKLNRFNSELVHEILCLEKELKEEKSKH-----SEQNELMADISKRIQSLEDES 150
L A E N+ +E+ ++ ++E+++ K H S Q L A+ R ++L +
Sbjct: 1558 ILRAQLE-FNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKK 1616
Query: 151 KS-------------LKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQES------ 191
K AEA+ K Q+ + +I++ DA + N +L+E+
Sbjct: 1617 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVER 1676
Query: 192 --------------------------QKQLLQEAE---VWKEQVSELIKQKRTFE----- 217
+++L++ +E + Q + LI QK+ +
Sbjct: 1677 RNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQ 1736
Query: 218 ---DSKVHAEQVLNDKENHIKTLT------ERLLKMKDGVAMLEEDVTDDDNLELEMNSE 268
+ + ++ N +E K +T E L K +D A LE ++ N E
Sbjct: 1737 LQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE---------RMKKNME 1787
Query: 269 SEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ 328
+K L H A L+G + Q+ ++L ++ L+
Sbjct: 1788 Q------------TIKDLQHRLD-EAEQIALKGGKKQL-----------QKLEARVRELE 1823
Query: 329 TEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVD 388
E + Q N +K ++++K +T +E+ L R + +K +L+ + + +
Sbjct: 1824 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 1883
Query: 389 EMISHATEELETYRKRAKDLKEFEKTIHFYQKKIILHEKKAHD 431
E A L +RK +L E E+ + ++ K+ D
Sbjct: 1884 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRD 1926
Score = 47.4 bits (111), Expect = 5e-05
Identities = 59/294 (20%), Positives = 126/294 (42%), Gaps = 20/294 (6%)
Query: 184 ENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLK 243
+++E ++ + +E KE + + +++ E+ V Q ND + ++ + L
Sbjct: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 244 MKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGER 303
++ L ++ + EMN ED + N A K+ KL L+ +
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEM-NAELTAKKR-----KLEDECSELKRDI 954
Query: 304 NQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQENE 363
+ + + L++V+K K +KNL E A L E + LQ+ + + Q E
Sbjct: 955 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE 1014
Query: 364 MKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFYQKKI- 422
K+ + + K +LE++ VD++ +E + + ++ E + Q+ I
Sbjct: 1015 DKV--NTLTKAKVKLEQQ-----VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM 1067
Query: 423 -ILHEKKAHDNWSAAWTAERNLNDLRKEN-----AHNRQKLTEIEFKIKLLEKD 470
+ ++K+ D E N + R E+ + ++KL E++ +I+ LE++
Sbjct: 1068 DLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEE 1121
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 81.3 bits (199), Expect = 3e-15
Identities = 100/459 (21%), Positives = 198/459 (43%), Gaps = 69/459 (15%)
Query: 65 KFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNS---ELVHEILCLEKE 121
K +L + E E+E + + EK + Q ++A + LN +L+ + LE +
Sbjct: 862 KETLEKSEARRKELEEKMVSLLQEKNDLQLQ-VQAEQDNLNDAEERCDQLIKNKIQLEAK 920
Query: 122 LKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQD- 180
+KE + ++ E+ A+++ + + LEDE LK + + ++T + + + E ++++
Sbjct: 921 VKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 980
Query: 181 -------------AWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVL 227
KE LQE+ +Q L + +V +++V+ L K K E E L
Sbjct: 981 TEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSL 1040
Query: 228 NDKENHIKTLTERLLKMKDGVAMLEEDVTD--DDNLELE------------MNSESEDGA 273
++ L K++ + + +E + D +D L+LE NS+ ED
Sbjct: 1041 EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQ 1100
Query: 274 YLDNPPKGALKKLIHAAKLNASLKTLEGERN---QIYIQLSEVDKTKEELTEHIKNLQTE 330
L + LK+ + A++ + LE ER ++ S++ + EE++E ++
Sbjct: 1101 VLALQLQKKLKE--NQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGA 1158
Query: 331 QASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRK-------------LIVEEKCR 377
+ N E+E QK+++ L+ T ++ L +K + K +
Sbjct: 1159 TSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQK 1218
Query: 378 LEKEEKLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFYQKKIILHEKKAHDNWSAAW 437
LEKE+ K++ + T +E K +L++ +T+ E +A++
Sbjct: 1219 LEKEKSEFKLE--LDDVTSNMEQIIKAKANLEKVSRTL----------EDQANEYRVKLE 1266
Query: 438 TAERNLND-------LRKENAHNRQKLTEIEFKIKLLEK 469
A+R+LND L+ EN ++L E E I L +
Sbjct: 1267 EAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTR 1305
Score = 74.3 bits (181), Expect = 4e-13
Identities = 93/433 (21%), Positives = 179/433 (41%), Gaps = 46/433 (10%)
Query: 41 YVRREKKFAVALSGLIE---EKCKLLEKFSLVQK--EYEGYEVESSLKNASFEKEATEAQ 95
+ R K +S L E E K + + V+K E E E++S+L+ A E E +
Sbjct: 1500 FKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGK 1559
Query: 96 SLEATCEKLNRFNSELVHEILCLEKELKEEKSKH-----SEQNELMADISKR-------- 142
L A E N+ +E+ ++ ++E+++ K H S Q L A+ R
Sbjct: 1560 ILRAQLE-FNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKK 1618
Query: 143 -----IQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQ 197
+ +E + AEA+ K Q+ + +I++ DA + N +L+E+ + +
Sbjct: 1619 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVER 1678
Query: 198 EAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIK-------TLTERLLKMKDGVAM 250
+ + ++ EL E S+ AEQ L + ++ +L + KM+ +
Sbjct: 1679 RNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQ 1738
Query: 251 L----EEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQI 306
L EE V + N E + D A + K K+ +A L K +E +
Sbjct: 1739 LQSEVEEAVQECRNAEEKAKKAITDAAMMAEELK---KEQDTSAHLERMKKNMEQTIKDL 1795
Query: 307 YIQLSEVD--------KTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTEL 358
+L E + K ++L ++ L+ E + Q N +K ++++K +T
Sbjct: 1796 QHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQ 1855
Query: 359 YQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFY 418
+E++ L R + +K +L+ + + +E A L +RK +L E E+
Sbjct: 1856 TEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIA 1915
Query: 419 QKKIILHEKKAHD 431
+ ++ K+ D
Sbjct: 1916 ESQVNKLRAKSRD 1928
Score = 69.3 bits (168), Expect = 1e-11
Identities = 88/426 (20%), Positives = 174/426 (40%), Gaps = 29/426 (6%)
Query: 55 LIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHE 114
L E K KL ++ ++ E + S + + E + L E+ N + L +
Sbjct: 1388 LEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 1447
Query: 115 ILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERL 174
+K L E K K+ E ++S + E++SL +++ FK A EE L
Sbjct: 1448 QRNFDKILAEWKQKYEESQS-------ELESSQKEARSLSTEL------FKLKNAYEESL 1494
Query: 175 EIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHI 234
E ++ +EN LQE L ++ + V EL K ++ E K+ + L + E +
Sbjct: 1495 E-HLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASL 1553
Query: 235 KTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNA 294
+ ++L+ + ++ ++ + E + E E +L+ + A +
Sbjct: 1554 EHEEGKILRAQLEFNQIKAEI---ERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSR 1610
Query: 295 S-----LKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQ 349
+ K +EG+ N++ IQLS ++ E + +K+LQ+ Q + N L+
Sbjct: 1611 NEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK 1670
Query: 350 QKLKVM---TELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMI----SHATEELETYR 402
+ + ++ L Q +L + E+ R E++L + E + S T + +
Sbjct: 1671 ENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKK 1730
Query: 403 KRAKDLKEFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEF 462
K DL + + + ++ E+KA + A L + +AH + +E
Sbjct: 1731 KMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQ 1790
Query: 463 KIKLLE 468
IK L+
Sbjct: 1791 TIKDLQ 1796
Score = 67.8 bits (164), Expect = 4e-11
Identities = 93/402 (23%), Positives = 172/402 (42%), Gaps = 48/402 (11%)
Query: 76 YEVESSLKNASFEKEAT----EAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSE 131
++++ LK+A EKE E ++ T EK EL +++ L +E + + +
Sbjct: 836 FKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQA 895
Query: 132 QNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQES 191
+ + + D +R L L+++V E ERLE D + N+EL
Sbjct: 896 EQDNLNDAEERCDQLIKNKIQLEAKVKEMN----------ERLE----DEEEMNAELTAK 941
Query: 192 QKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAML 251
+++L E K+ + +L E + E+ + EN +K LTE + + + +A L
Sbjct: 942 KRKLEDECSELKKDIDDL-------ELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKL 994
Query: 252 EEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLS 311
T + E + ++ D ++ +L K KL + LEG Q
Sbjct: 995 ----TKEKKALQEAHQQALDDLQVEEDKVNSLSK--SKVKLEQQVDDLEGSLEQEKKVRM 1048
Query: 312 EVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKL-----QQKLKVMTELYQENEMKL 366
++++ K +L +K Q L+++ E + +K QQ K+ E Q ++L
Sbjct: 1049 DLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDE--QVLALQL 1106
Query: 367 YRKLIVEEKCRLEK-EEKL-------SKVDEMISHATEELETYRKRAKDLKEFEKT-IHF 417
+KL E + R+E+ EE+L +KV+++ S + ELE +R ++ I
Sbjct: 1107 QKKL-KENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEM 1165
Query: 418 YQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTE 459
+K+ +K D A E LRK++A + +L E
Sbjct: 1166 NKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGE 1207
Score = 60.5 bits (145), Expect = 6e-09
Identities = 88/388 (22%), Positives = 169/388 (43%), Gaps = 40/388 (10%)
Query: 55 LIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEK--LNRFNSELV 112
L +K KL ++ S ++K+ + ++E +L EK ATE + T E L+ ++L
Sbjct: 938 LTAKKRKLEDECSELKKDID--DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 995
Query: 113 HEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEE 172
E L++ ++ + + + +SK LE + L+ + + K + +
Sbjct: 996 KEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKR 1055
Query: 173 RLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQV---LND 229
+LE +++ + +L+ + QL E K++ ++ +Q ED +V A Q+ L +
Sbjct: 1056 KLEGDLKLTQESIMDLENDKLQL---EEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKE 1112
Query: 230 KENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSE--SEDGAYLDNPPKGALKKLI 287
+ I+ L E L + A +E+ + D + ELE SE E G + K+
Sbjct: 1113 NQARIEELEEELEAERTARAKVEK-LRSDLSRELEEISERLEEAGGATSVQIEMNKKREA 1171
Query: 288 HAAKLNASLK--TLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESE- 344
K+ L+ TL+ E ++ D EL E I NLQ + L+ E + F+ E
Sbjct: 1172 EFQKMRRDLEEATLQHEATAAALRKKHADSV-AELGEQIDNLQRVKQKLEKEKSEFKLEL 1230
Query: 345 ---NQKLQQKLKVMTELYQ-----ENEMKLYRKLIVE----------EKCRLEKE----- 381
++Q +K L + E++ YR + E ++ +L+ E
Sbjct: 1231 DDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELA 1290
Query: 382 EKLSKVDEMISHATEELETYRKRAKDLK 409
+L + + +IS T +Y ++ +DLK
Sbjct: 1291 RQLEEKEALISQLTRGKLSYTQQMEDLK 1318
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 80.9 bits (198), Expect = 4e-15
Identities = 112/507 (22%), Positives = 209/507 (41%), Gaps = 66/507 (13%)
Query: 24 FAVLFLWRSFRSVTSRLYVRREKKFAVALSGLIEEK--CKLLEKFSLVQKEY---EGYEV 78
F + + RSF +V ++ K L EK + E F ++E E
Sbjct: 816 FCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRK 875
Query: 79 ESSLKNASFEKEATEAQSLEATCEKLNRFNSE-----LVHEILCLEKELKEEKSKHSEQN 133
E K S +E + Q L+ E N ++E L+ + LE ++KE + E+
Sbjct: 876 ELEEKMVSLLQEKNDLQ-LQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEE 934
Query: 134 ELMADISKRIQSLEDESKSLKSQVAEAKMTF----KRFQANEER----------LEIEIQ 179
E+ +++ + ++LED+ SLK + + ++T K A E + LE I
Sbjct: 935 EMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENIS 994
Query: 180 DAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTE 239
KE LQE+ +Q L + +V +++V+ LIK E E L ++ L
Sbjct: 995 KLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLER 1054
Query: 240 RLLKMKDGVAMLEEDVTDDDNLELEMNSE--------SEDGAYLDNPPKGALKKLIHAAK 291
K++ + M +E + D +N + ++ + S+ A +D+ +L+ +
Sbjct: 1055 AKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKE 1114
Query: 292 LNASLKTLEGE-------RNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESE 344
L A ++ LE E R +I Q S++ + EE++E ++ ++ N E+E
Sbjct: 1115 LQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAE 1174
Query: 345 NQKLQQKLKVMTELYQENEMKLYRKLI---------------VEEKCRLEKEEKLSKVDE 389
QK+++ L+ T ++ L +K V++K EK E ++D+
Sbjct: 1175 FQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDD 1234
Query: 390 MISHATEELETYRKRAKDLKEFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLND--LR 447
M S+ +E K +++ +T+ +I KA D + N+ L+
Sbjct: 1235 MASN----IEALSKSKSNIERTCRTVEDQFSEI-----KAKDEQQTQLIHDLNMQKARLQ 1285
Query: 448 KENAHNRQKLTEIEFKIKLLEKDPYGL 474
+N ++ E E I L K L
Sbjct: 1286 TQNGELSHRVEEKESLISQLTKSKQAL 1312
Score = 70.5 bits (171), Expect = 5e-12
Identities = 100/435 (22%), Positives = 195/435 (44%), Gaps = 47/435 (10%)
Query: 55 LIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHE 114
L E K KL ++ +Q+ E E +S K AS EK Q L+ E L R
Sbjct: 1390 LEEAKKKLAQR---LQEAEENTETANS-KCASLEKTK---QRLQGEVEDLMRDLERSHTA 1442
Query: 115 ILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERL 174
L+K+ + +E + + + +++ + ES+SL +++ FK A EE +
Sbjct: 1443 CATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTEL------FKMRNAYEEVV 1496
Query: 175 EIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHI 234
+ +++ +EN LQE L ++ + + E K K+ E K + L + E +
Sbjct: 1497 D-QLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSL 1555
Query: 235 KTLTERLLKMKDGVAMLEEDVT------DDDNLELEMNSESEDGAYLDNPPKGALKKLIH 288
+ ++L+++ ++ ++ ++ D++ +L+ NS+ A L + ++
Sbjct: 1556 EHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEA-LQSVLDAEIRSRND 1614
Query: 289 AAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFES---EN 345
A +L K +EG+ N++ IQL + ++ E K+L+T Q L+ H + N
Sbjct: 1615 ALRLK---KKMEGDLNEMEIQLGH---SNRQMAETQKHLRTVQGQLKDSQLHLDDALRSN 1668
Query: 346 QKLQQKLKVMTE-----LYQENEMKLYRKLIVEEKCRLEKEEKL---SKVDEMISHATEE 397
+ L+++L ++ L + EMK+ + E RL ++E L +V + S T
Sbjct: 1669 EDLKEQLAIVERRNGLLLEELEEMKVALEQ-TERTRRLSEQELLDASDRVQLLHSQNTSL 1727
Query: 398 LETYRKRAKDLKEFEKTI-HFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKE---NAHN 453
+ T +K D+ + + + + Q+ EK AA AE +L+KE +AH
Sbjct: 1728 INTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAE----ELKKEQDTSAHL 1783
Query: 454 RQKLTEIEFKIKLLE 468
+ +E +K L+
Sbjct: 1784 ERMKKNLEQTVKDLQ 1798
Score = 64.7 bits (156), Expect = 3e-10
Identities = 100/471 (21%), Positives = 200/471 (42%), Gaps = 58/471 (12%)
Query: 29 LWRSFRSVTSRLYVRREKKFAVALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASF- 87
L R ++ RL ++ + A S IE K +F ++++ E ++ A+
Sbjct: 1143 LARELEEISERL-----EEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLR 1197
Query: 88 EKEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLE 147
+K+A L + L R +L E L+ E+ + S ++ ++I + +++E
Sbjct: 1198 KKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVE 1257
Query: 148 DESKSLKSQ-------VAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAE 200
D+ +K++ + + M R Q L +++ S+L +S++ L Q+ E
Sbjct: 1258 DQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLE 1317
Query: 201 VWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDN 260
K Q+ E K K ++ HA L + L E+ + ++ A L+ ++ ++
Sbjct: 1318 ELKRQMEEETKAK----NAMAHA---LQSSRHDCDLLREQYEEEQEAKAELQRALSKANS 1370
Query: 261 LELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEEL 320
+ ++ E A KK KL L+ E + + ++KTK+ L
Sbjct: 1371 EVAQWRTKYETDAIQRTEELEEAKK-----KLAQRLQEAEENTETANSKCASLEKTKQRL 1425
Query: 321 TEHIKNL-------QTEQASLQSENTHFESENQKLQQKL---KVMTELYQENEMKLYRKL 370
+++L T A+L + +F+ + +QKL + E Q+ L +L
Sbjct: 1426 QGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTEL 1485
Query: 371 ---------IVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFYQKK 421
+V++ L +E K + E IS TE++ + K+L+E EKT KK
Sbjct: 1486 FKMRNAYEEVVDQLETLRRENK--NLQEEISDLTEQI---AETGKNLQEAEKT-----KK 1535
Query: 422 IILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKI--KLLEKD 470
++ EK D A E +L + + +L++++ ++ K++EKD
Sbjct: 1536 LVEQEKS--DLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKD 1584
Score = 37.4 bits (85), Expect = 0.051
Identities = 36/171 (21%), Positives = 71/171 (41%), Gaps = 8/171 (4%)
Query: 53 SGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELV 112
+ LI K KL + Q E E ES +K T+A + +K ++ L
Sbjct: 1725 TSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1784
Query: 113 HEILCLEKELKEEKSKHSEQNEL--------MADISKRIQSLEDESKSLKSQVAEAKMTF 164
LE+ +K+ + + E +L + + R++ LE+E + + AEA
Sbjct: 1785 RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGA 1844
Query: 165 KRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRT 215
+++ + + + ++ K LQ+ +L + + +K Q E +Q T
Sbjct: 1845 HKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANT 1895
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 80.1 bits (196), Expect = 7e-15
Identities = 91/447 (20%), Positives = 201/447 (44%), Gaps = 37/447 (8%)
Query: 51 ALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSE 110
ALS + +K K + KE + +E + E+ + L+ + + SE
Sbjct: 180 ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSE 239
Query: 111 LVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQAN 170
+ + L+++L+ K +Q +L A+ + L+ S L++QV E ++ + Q
Sbjct: 240 IQLNVKELKRKLERAKLLLPQQ-QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 298
Query: 171 EERL---EIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTF---EDSKVHAE 224
EE++ E +IQ+ W+E ++QE ++++ ++ E +EQ ++ +Q+ E+ E
Sbjct: 299 EEKMWRQEEKIQE-WEE--KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 355
Query: 225 QVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNL--ELEMNSESEDGAYLDNPPKGA 282
+++ +KE ++ L E + + ++ + LEE + + + + + E E E + +
Sbjct: 356 EMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 415
Query: 283 LKKLIHAAKLNASLKTLEGERNQIYIQ---LSEVDKTKEE---------LTEHIKNLQTE 330
K K+ + + + +++ Q + E +K +EE + K + E
Sbjct: 416 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 475
Query: 331 QASLQSENTHFESENQK-------LQQKLKVMTELYQENEMKLYR---KLIVEEKCRLEK 380
+ Q E H + + +K ++K+ E +E E K++R K+ +E+ E+
Sbjct: 476 EIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ 535
Query: 381 EEKLSKVDEMISHATE---ELETYRKRAKDLKEFEKTIHFYQKKIILHEKKAHDNWSAAW 437
EEK+ + +EM+ E E E + + ++ E+ I ++KI ++K + W
Sbjct: 536 EEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIW 595
Query: 438 TAERNLNDLRKENAHNRQKLTEIEFKI 464
E + + + +K+ E E K+
Sbjct: 596 EQEEKIREQEEMMQEQEEKMWEQEEKM 622
Score = 74.7 bits (182), Expect = 3e-13
Identities = 89/412 (21%), Positives = 187/412 (45%), Gaps = 34/412 (8%)
Query: 70 QKEYEGYEVESSLKNA-SFEKEATEAQSLEATCEK-LNRFNSELVHEILCLEKELKEEKS 127
Q E E ++ S L ++ F E +A S AT +K +R+ EL E L EL
Sbjct: 155 QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTI 214
Query: 128 KHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQA--NEERLEIEIQDAWKEN 185
E E A + +++Q +E E ++ V E K +R + +++L+ E KE
Sbjct: 215 TDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 274
Query: 186 SELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHA-EQVLNDKENHIKTLTERLLKM 244
+ + ++E E+W ++++ ++K ++ K+ E+ + ++E I+ E++ +
Sbjct: 275 QSVSAKLQAQVEENELWN-RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333
Query: 245 KDGVAMLEEDVTDDDNL---ELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEG 301
++ + EE + + + + EM E E+ +L + E
Sbjct: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEE----------------KMRRLEEMMWEKEE 377
Query: 302 ERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQE 361
+ ++ ++ E +K +E+ K + E+ Q + E++ + ++K++ E +E
Sbjct: 378 KIRELEEKMHEQEKIREQ---EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 434
Query: 362 NEMKLYRKLI-VEEKCRLEKEEKLSKVDEMISHAT---EELETYRKRAKDLKEFEKTIHF 417
E K++R+ + E+ ++ +EEK + +EM E+ E +R++ K + E EK I
Sbjct: 435 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK-MHEQEK-IRK 492
Query: 418 YQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEK 469
++K+ E+K HD E + ++ +K+ E E KI+ E+
Sbjct: 493 QEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEE 544
Score = 72.4 bits (176), Expect = 1e-12
Identities = 72/371 (19%), Positives = 155/371 (41%), Gaps = 54/371 (14%)
Query: 124 EEKSKHSEQNELMADISKRIQS---LEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQD 180
E+K+ H Q L ++ ++ + L + L+ + ++ K+ + L + D
Sbjct: 110 EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHD 169
Query: 181 AWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTER 240
+WK EL+++ + + + + EL K++ E + T+T+
Sbjct: 170 SWKFAGELEQALSAVATQKKKADRYIEELTKERDAL------------SLELYRNTITDE 217
Query: 241 LLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLE 300
LK K+ + + + + E+++N + LK+ + AKL + L+
Sbjct: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKE-------------LKRKLERAKLLLPQQQLQ 264
Query: 301 GERNQIYIQLSEVDK------TKEELTEHIKNLQTEQASLQSEN-THFESENQKLQQKLK 353
E + + +L V + EL + Q E+ Q E +E + Q+ ++K++
Sbjct: 265 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324
Query: 354 VMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEEL----ETYRKRAKDLK 409
E +E E K+ R +E+ EKEEK+ + +EM+ E++ E ++ + ++
Sbjct: 325 EQEEKIREQEEKMRR----QEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIR 380
Query: 410 EFEKTIHFYQK-----------KIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLT 458
E E+ +H +K + I ++K + + W E + + ++ +K+
Sbjct: 381 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 440
Query: 459 EIEFKIKLLEK 469
E KI EK
Sbjct: 441 RQEEKIHEQEK 451
Score = 67.8 bits (164), Expect = 4e-11
Identities = 66/387 (17%), Positives = 176/387 (45%), Gaps = 19/387 (4%)
Query: 29 LWRSFRSVTSRLYVRREKKFAVALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFE 88
LW R+E+K + E++ K+ E+ ++++ E + + E
Sbjct: 290 LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 349
Query: 89 KEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLED 148
K + + + EK+ R + + E++++E + K EQ ++ KR Q E
Sbjct: 350 KMRRQEEMMWEKEEKMRRLEEMMWEK----EEKIRELEEKMHEQEKIREQEEKR-QEEEK 404
Query: 149 ESKSLKSQVAEAKM--TFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQV 206
+ K Q EAKM ++ + EE++ + + W++ ++ E +K ++E E +EQ
Sbjct: 405 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK--IREEEKRQEQE 462
Query: 207 SELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMN 266
++++ E ++ ++ ++ I+ E++ + ++ + EE + + + +M
Sbjct: 463 EMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEE---KMW 519
Query: 267 SESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKN 326
+ E + + +K+ ++ + GE+ + + ++ + +E++ E +
Sbjct: 520 RQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEK 579
Query: 327 LQTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYR---KLIVEEKCRLEKEEK 383
++ ++ ++ + E + + ++K++ E+ QE E K++ K+ +E+ E+EEK
Sbjct: 580 IREQKEKIREQ----EEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 635
Query: 384 LSKVDEMISHATEELETYRKRAKDLKE 410
+ + +E + L ++ ++ +E
Sbjct: 636 MRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 65.5 bits (158), Expect = 2e-10
Identities = 66/342 (19%), Positives = 154/342 (45%), Gaps = 40/342 (11%)
Query: 57 EEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEIL 116
EEK + LE+ + +KE + E+E + +E E + E + + E ++
Sbjct: 362 EEKMRRLEEM-MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK-RQEQEAKMW 419
Query: 117 CLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEI 176
E++++E++ K EQ + M ++I E + K Q E EE++
Sbjct: 420 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE------EMWRQEEKIR- 472
Query: 177 EIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKT 236
E ++ W++ ++ E +K QE +VW++ E+ ++D+E I+
Sbjct: 473 EQEEIWRQKEKMHEQEKIRKQEEKVWRQ-------------------EEKMHDQEEKIRE 513
Query: 237 LTERLLKMKDGVAMLEEDVTDDDNL---ELEMNSESEDGAYLDNPPKGALKKLIHAAKLN 293
E++ + ++ + EE + + + + EM E E+ +K+ K+
Sbjct: 514 QEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE------EKMQEQEKMR 567
Query: 294 ASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLK 353
+ + + +I Q ++ + +E++ E + ++ ++ +Q + + +K+ ++ +
Sbjct: 568 RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627
Query: 354 VMTELYQENEMKLYRKLIVEEKCRL-EKEEKLSKVDEMISHA 394
M E QE +M+ + + E++ RL ++EEK+ + E + A
Sbjct: 628 KMQE--QEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 667
Score = 38.9 bits (89), Expect = 0.018
Identities = 31/200 (15%), Positives = 93/200 (46%), Gaps = 9/200 (4%)
Query: 29 LWRSFRSVTSRLYVRR-EKKFAVALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASF 87
+WR + + +R+ E+K + +++ K+ E+ + ++ E +
Sbjct: 477 IWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQE 536
Query: 88 EKEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLE 147
EK + + ++ EK+ ++ + ++++ ++ K EQ E + + ++I+ E
Sbjct: 537 EKIREQEEMMQEQEEKMGEQEEKMQEQ-----EKMRRQEEKIREQEEKIREQKEKIREQE 591
Query: 148 DESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVS 207
++ + ++ E + + Q EE++ + + ++ ++QE ++++ ++ E EQ
Sbjct: 592 EKIWEQEEKIREQE---EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 648
Query: 208 ELIKQKRTFEDSKVHAEQVL 227
L +Q+ ++ + H E +
Sbjct: 649 RLRQQEEKMQEHQEHLEAAI 668
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 79.7 bits (195), Expect = 9e-15
Identities = 86/426 (20%), Positives = 172/426 (40%), Gaps = 56/426 (13%)
Query: 69 VQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSK 128
++++Y E + K ++E + ++ E +L E ++ +++ ++
Sbjct: 451 LRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAE 510
Query: 129 HSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSEL 188
H + D+ + + E+E +SL S++ + ++ ++ + +L Q + L
Sbjct: 511 HEAAQQ---DLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESL 567
Query: 189 QESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQ---VLNDKENHIKTLTERLLKMK 245
Q + +L++ E K Q+ + Q + V AE+ V+ +K+ IK + L +
Sbjct: 568 QMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASER 627
Query: 246 DGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQ 305
D + EE++ D N+ + +E + L N A +L E +
Sbjct: 628 DRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHEL-------------EKMQQS 674
Query: 306 IYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMK 365
+Y++ ++ +E+L I N E L +N +SE QKLQ + +M
Sbjct: 675 VYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQM- 733
Query: 366 LYRKLIVEEKCRLEKEEKLSKVDEM-------ISHATEELETYR-------KRAKDLK-- 409
EKC EK+EKL V+E+ ++ EEL R K +DLK
Sbjct: 734 --------EKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAK 785
Query: 410 ------------EFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKL 457
E +K IH KI E+ E+ + DL++E ++++
Sbjct: 786 QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEI 845
Query: 458 TEIEFK 463
++ +
Sbjct: 846 GNVQLE 851
Score = 66.2 bits (160), Expect = 1e-10
Identities = 100/438 (22%), Positives = 187/438 (42%), Gaps = 38/438 (8%)
Query: 42 VRREKKFAVALSGLIEEKCKLLE---------KFSLVQKEYEGYEVESSLKNASFEKEAT 92
V+ EK ++++ ++E LL+ K L +KE + L++ E E+
Sbjct: 848 VQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESL 907
Query: 93 EAQSLEATCEKLNRFNSELVHEILCL-----EKELKEEKSKHSEQNELMADISKRIQSLE 147
+A E L +S E L + E ELK ++ E+ ++ ++ +Q ++
Sbjct: 908 KAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQ 967
Query: 148 DESKSLKSQVAEAK----MTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWK 203
DE+K KSQ+ + K F +EE L++ I + KE S L L E +
Sbjct: 968 DENKLFKSQIEQLKQQNYQQASSFPPHEELLKV-ISEREKEISGLWNELDSLKDAVEHQR 1026
Query: 204 EQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLEL 263
++ ++L ++ ++ E++L DK N KT ER ++ + V + ++V ++
Sbjct: 1027 KKNNDLREKNWEAMEALASTEKMLQDKVN--KTSKERQQQV-EAVELEAKEVLKKLFPKV 1083
Query: 264 EMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLE---GERNQIYIQLS-EVDKTKEE 319
+ S G +L K A K+ + + +K LE E ++++ L E +K K
Sbjct: 1084 SVPSNLSYGEWLHGFEKKA-KECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSV 1142
Query: 320 LTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLE 379
L E LQ Q S++ E ++ + + + +K M + +E +L R L E K
Sbjct: 1143 LAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELER-LRSENKDIEN 1201
Query: 380 KEEKLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFYQKKIILHEKKAHDNWSAAWTA 439
+ ++ + A E TY ++LK+ + +KK D++S A
Sbjct: 1202 LRREREHLEMELEKAEMERSTYVTEVRELKDLLTEL----------QKKLDDSYSEAVRQ 1251
Query: 440 ERNLNDLRKENAHNRQKL 457
LN L+ + KL
Sbjct: 1252 NEELNLLKAQLNETLTKL 1269
Score = 49.7 bits (117), Expect = 1e-05
Identities = 103/500 (20%), Positives = 207/500 (41%), Gaps = 93/500 (18%)
Query: 57 EEKCKLLEKF---SLVQKEYEGYEVES-SLKNASFEKEATEAQ-------SLEATCEKLN 105
+EK K +E+ L+Q + E+ + +N+S KE + + S + E+L
Sbjct: 741 DEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELK 800
Query: 106 RFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDE----------SKSLKS 155
+ E +I +E+ L+ E K + + + + D+ + I++L++E S+ S
Sbjct: 801 KVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITS 860
Query: 156 QVAEAK--MTFKRFQANEERLEIE------------IQDAWKENSELQESQKQLLQEAEV 201
+V E + + K Q N + +E +QD +EN L+ +++ Q
Sbjct: 861 KVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLK 920
Query: 202 WKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKD----GVAMLEEDVTD 257
S+ FE+ ++ VL +KEN +K L E +LK ++ L +DV D
Sbjct: 921 EASSASQ-------FEELEI----VLKEKENELKRL-EAMLKERESDLSSKTQLLQDVQD 968
Query: 258 DDNL---ELEMNSESEDGAYLDNPPKGALKKLI--HAAKLNASLKTLEGERNQIYIQLSE 312
++ L ++E + PP L K+I +++ L+ ++ + Q +
Sbjct: 969 ENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKK 1028
Query: 313 VDKTKEELTEHIKNLQTEQASLQSENTHFESENQ---------------KLQQKLKVMTE 357
+ +E+ E ++ L + + LQ + E Q KL K+ V +
Sbjct: 1029 NNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSN 1088
Query: 358 LYQENEMKLYRKLIVE--------EKCRLEKEEKLSKVDEMISHATEELETYRKRAKD-- 407
L + + K E E+ ++ E KL + DEM + E E Y+ +
Sbjct: 1089 LSYGEWLHGFEKKAKECMAGTSGSEEVKV-LEHKLKEADEMHTLLQLECEKYKSVLAETE 1147
Query: 408 --LKEFEKTIHFYQKKIILHEKKAHDN----WSAAWTAERNLNDLRK-----ENAHNRQK 456
L++ ++++ + K + ++H S+ ++E+ L LR EN ++
Sbjct: 1148 GILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRRERE 1207
Query: 457 LTEIEFKIKLLEKDPYGLDV 476
E+E + +E+ Y +V
Sbjct: 1208 HLEMELEKAEMERSTYVTEV 1227
Score = 49.3 bits (116), Expect = 1e-05
Identities = 73/372 (19%), Positives = 160/372 (43%), Gaps = 44/372 (11%)
Query: 120 KELKEEKSKHSEQ-NELMADISKRIQSLEDESKSLKSQV----AEAKMTFKRFQANEERL 174
K+L +E E+ N ++ + RI +LE E ++++ E + +FQ E++
Sbjct: 356 KQLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQM 415
Query: 175 EIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKR---------TFEDSKVHAEQ 225
E EI +EN L+++ + E +Q +EL K ++ T + K+ E+
Sbjct: 416 EAEIAHLKQENGILRDAVSNTTNQLE--SKQSAELNKLRQDYARLVNELTEKTGKLQQEE 473
Query: 226 VLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKK 285
V K+N + T+ +++++ EE + + + + A D K K+
Sbjct: 474 V--QKKNAEQAATQLKVQLQEAERRWEEVQS-----YIRKRTAEHEAAQQDLQSKFVAKE 526
Query: 286 LIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESEN 345
L++ L + Q+ +L ++ +++++ ++LQ + + +N +++
Sbjct: 527 -NEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQI 585
Query: 346 QKLQQKLKVMT-------ELY-----QENEMKLYRKLIVEEKCRL-EKEEKLSKVDEM-- 390
Q+ ++ T EL+ ++ ++K + E+ RL KEE+L + M
Sbjct: 586 QQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNF 645
Query: 391 -ISHATEELETYRKR----AKDLKEFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLND 445
+ ++L+ A +L++ +++++ KI L E++ S + LND
Sbjct: 646 LLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILND 705
Query: 446 LRKENAHNRQKL 457
K QKL
Sbjct: 706 QNKALKSEVQKL 717
Score = 35.4 bits (80), Expect = 0.19
Identities = 32/174 (18%), Positives = 72/174 (41%), Gaps = 4/174 (2%)
Query: 85 ASFEKEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQ 144
+SF E + L + + + E H + LEK E + +E EL +++ +
Sbjct: 1180 SSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQK 1239
Query: 145 SLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKE 204
L+D Q E + + +L E + K +L ++Q+ L E+ +
Sbjct: 1240 KLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSL----ELIQS 1295
Query: 205 QVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDD 258
++ + E+S V E ++KE +L + + +++ + + + +T +
Sbjct: 1296 KIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKE 1349
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 79.7 bits (195), Expect = 9e-15
Identities = 86/426 (20%), Positives = 172/426 (40%), Gaps = 56/426 (13%)
Query: 69 VQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSK 128
++++Y E + K ++E + ++ E +L E ++ +++ ++
Sbjct: 451 LRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAE 510
Query: 129 HSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSEL 188
H + D+ + + E+E +SL S++ + ++ ++ + +L Q + L
Sbjct: 511 HEAAQQ---DLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESL 567
Query: 189 QESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQ---VLNDKENHIKTLTERLLKMK 245
Q + +L++ E K Q+ + Q + V AE+ V+ +K+ IK + L +
Sbjct: 568 QMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASER 627
Query: 246 DGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQ 305
D + EE++ D N+ + +E + L N A +L E +
Sbjct: 628 DRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHEL-------------EKMQQS 674
Query: 306 IYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMK 365
+Y++ ++ +E+L I N E L +N +SE QKLQ + +M
Sbjct: 675 VYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQM- 733
Query: 366 LYRKLIVEEKCRLEKEEKLSKVDEM-------ISHATEELETYR-------KRAKDLK-- 409
EKC EK+EKL V+E+ ++ EEL R K +DLK
Sbjct: 734 --------EKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAK 785
Query: 410 ------------EFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKL 457
E +K IH KI E+ E+ + DL++E ++++
Sbjct: 786 QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEI 845
Query: 458 TEIEFK 463
++ +
Sbjct: 846 GNVQLE 851
Score = 63.9 bits (154), Expect = 5e-10
Identities = 88/415 (21%), Positives = 174/415 (41%), Gaps = 54/415 (13%)
Query: 42 VRREKKFAVALSGLIEEKCKLLE---------KFSLVQKEYEGYEVESSLKNASFEKEAT 92
V+ EK ++++ ++E LL+ K L +KE + L++ E E+
Sbjct: 848 VQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESL 907
Query: 93 EAQSLEATCEKLNRFNSELVHEILCL-----EKELKEEKSKHSEQNELMADISKRIQSLE 147
+A E L +S E L + E ELK ++ E+ ++ ++ +Q ++
Sbjct: 908 KAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQ 967
Query: 148 DESKSLKSQVAEAK----MTFKRFQANEERLEI------EIQDAWKENSELQES------ 191
DE+K KSQ+ + K F +EE L++ EI W E L+++
Sbjct: 968 DENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRK 1027
Query: 192 -QKQLLQEAEVWKEQVSELIKQ--KRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGV 248
+ Q+ E + + E++K+ + S + + L+ E K ++ V
Sbjct: 1028 KNNERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEE-V 1086
Query: 249 AMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYI 308
+LE + + D + + E E + +G L+KL +++E E N+ +
Sbjct: 1087 KVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKL---------QRSVEQEENKWKV 1137
Query: 309 QLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYR 368
++ E KT IK +Q+ S + E SEN+ ++ + L EM+L +
Sbjct: 1138 KVDESHKT-------IKQMQSSFTSSEQELERLRSENKDIENLRREREHL----EMELEK 1186
Query: 369 KLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFYQKKII 423
+ E E ++++E ++ E +K A DL + ++++ Q KI+
Sbjct: 1187 AEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIV 1241
Score = 52.4 bits (124), Expect = 2e-06
Identities = 102/483 (21%), Positives = 200/483 (41%), Gaps = 88/483 (18%)
Query: 57 EEKCKLLEKF---SLVQKEYEGYEVES-SLKNASFEKEATEAQ-------SLEATCEKLN 105
+EK K +E+ L+Q + E+ + +N+S KE + + S + E+L
Sbjct: 741 DEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELK 800
Query: 106 RFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDE----------SKSLKS 155
+ E +I +E+ L+ E K + + + + D+ + I++L++E S+ S
Sbjct: 801 KVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITS 860
Query: 156 QVAEAK--MTFKRFQANEERLEIE------------IQDAWKENSELQESQKQLLQEAEV 201
+V E + + K Q N + +E +QD +EN L+ +++ Q
Sbjct: 861 KVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLK 920
Query: 202 WKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKD----GVAMLEEDVTD 257
S+ FE+ ++ VL +KEN +K L E +LK ++ L +DV D
Sbjct: 921 EASSASQ-------FEELEI----VLKEKENELKRL-EAMLKERESDLSSKTQLLQDVQD 968
Query: 258 DDNL---ELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVD 314
++ L ++E + PP L K+I + K + G N E+D
Sbjct: 969 ENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISERE-----KEISGLWN-------ELD 1016
Query: 315 KTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVE- 373
K+ + K Q +++ + +KL K+ V + L + + K E
Sbjct: 1017 SLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKEC 1076
Query: 374 -------EKCRLEKEEKLSKVDEMISHATEELETYRKRAKD----LKEFEKTIHFYQKKI 422
E+ ++ E KL + DEM + E E Y+ + L++ ++++ + K
Sbjct: 1077 MAGTSGSEEVKV-LEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKW 1135
Query: 423 ILHEKKAHDN----WSAAWTAERNLNDLRK-----ENAHNRQKLTEIEFKIKLLEKDPYG 473
+ ++H S+ ++E+ L LR EN ++ E+E + +E+ Y
Sbjct: 1136 KVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYV 1195
Query: 474 LDV 476
+V
Sbjct: 1196 TEV 1198
Score = 49.3 bits (116), Expect = 1e-05
Identities = 73/372 (19%), Positives = 160/372 (43%), Gaps = 44/372 (11%)
Query: 120 KELKEEKSKHSEQ-NELMADISKRIQSLEDESKSLKSQV----AEAKMTFKRFQANEERL 174
K+L +E E+ N ++ + RI +LE E ++++ E + +FQ E++
Sbjct: 356 KQLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQM 415
Query: 175 EIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKR---------TFEDSKVHAEQ 225
E EI +EN L+++ + E +Q +EL K ++ T + K+ E+
Sbjct: 416 EAEIAHLKQENGILRDAVSNTTNQLE--SKQSAELNKLRQDYARLVNELTEKTGKLQQEE 473
Query: 226 VLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKK 285
V K+N + T+ +++++ EE + + + + A D K K+
Sbjct: 474 V--QKKNAEQAATQLKVQLQEAERRWEEVQS-----YIRKRTAEHEAAQQDLQSKFVAKE 526
Query: 286 LIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESEN 345
L++ L + Q+ +L ++ +++++ ++LQ + + +N +++
Sbjct: 527 -NEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQI 585
Query: 346 QKLQQKLKVMT-------ELY-----QENEMKLYRKLIVEEKCRL-EKEEKLSKVDEM-- 390
Q+ ++ T EL+ ++ ++K + E+ RL KEE+L + M
Sbjct: 586 QQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNF 645
Query: 391 -ISHATEELETYRKR----AKDLKEFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLND 445
+ ++L+ A +L++ +++++ KI L E++ S + LND
Sbjct: 646 LLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILND 705
Query: 446 LRKENAHNRQKL 457
K QKL
Sbjct: 706 QNKALKSEVQKL 717
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 79.7 bits (195), Expect = 9e-15
Identities = 86/426 (20%), Positives = 172/426 (40%), Gaps = 56/426 (13%)
Query: 69 VQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSK 128
++++Y E + K ++E + ++ E +L E ++ +++ ++
Sbjct: 451 LRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAE 510
Query: 129 HSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSEL 188
H + D+ + + E+E +SL S++ + ++ ++ + +L Q + L
Sbjct: 511 HEAAQQ---DLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESL 567
Query: 189 QESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQ---VLNDKENHIKTLTERLLKMK 245
Q + +L++ E K Q+ + Q + V AE+ V+ +K+ IK + L +
Sbjct: 568 QMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASER 627
Query: 246 DGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQ 305
D + EE++ D N+ + +E + L N A +L E +
Sbjct: 628 DRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHEL-------------EKMQQS 674
Query: 306 IYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMK 365
+Y++ ++ +E+L I N E L +N +SE QKLQ + +M
Sbjct: 675 VYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQM- 733
Query: 366 LYRKLIVEEKCRLEKEEKLSKVDEM-------ISHATEELETYR-------KRAKDLK-- 409
EKC EK+EKL V+E+ ++ EEL R K +DLK
Sbjct: 734 --------EKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAK 785
Query: 410 ------------EFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKL 457
E +K IH KI E+ E+ + DL++E ++++
Sbjct: 786 QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEI 845
Query: 458 TEIEFK 463
++ +
Sbjct: 846 GNVQLE 851
Score = 66.2 bits (160), Expect = 1e-10
Identities = 100/438 (22%), Positives = 187/438 (42%), Gaps = 38/438 (8%)
Query: 42 VRREKKFAVALSGLIEEKCKLLE---------KFSLVQKEYEGYEVESSLKNASFEKEAT 92
V+ EK ++++ ++E LL+ K L +KE + L++ E E+
Sbjct: 848 VQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESL 907
Query: 93 EAQSLEATCEKLNRFNSELVHEILCL-----EKELKEEKSKHSEQNELMADISKRIQSLE 147
+A E L +S E L + E ELK ++ E+ ++ ++ +Q ++
Sbjct: 908 KAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQ 967
Query: 148 DESKSLKSQVAEAK----MTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWK 203
DE+K KSQ+ + K F +EE L++ I + KE S L L E +
Sbjct: 968 DENKLFKSQIEQLKQQNYQQASSFPPHEELLKV-ISEREKEISGLWNELDSLKDAVEHQR 1026
Query: 204 EQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLEL 263
++ ++L ++ ++ E++L DK N KT ER ++ + V + ++V ++
Sbjct: 1027 KKNNDLREKNWEAMEALASTEKMLQDKVN--KTSKERQQQV-EAVELEAKEVLKKLFPKV 1083
Query: 264 EMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLE---GERNQIYIQLS-EVDKTKEE 319
+ S G +L K A K+ + + +K LE E ++++ L E +K K
Sbjct: 1084 SVPSNLSYGEWLHGFEKKA-KECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSV 1142
Query: 320 LTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLE 379
L E LQ Q S++ E ++ + + + +K M + +E +L R L E K
Sbjct: 1143 LAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELER-LRSENKDIEN 1201
Query: 380 KEEKLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFYQKKIILHEKKAHDNWSAAWTA 439
+ ++ + A E TY ++LK+ + +KK D++S A
Sbjct: 1202 LRREREHLEMELEKAEMERSTYVTEVRELKDLLTEL----------QKKLDDSYSEAVRQ 1251
Query: 440 ERNLNDLRKENAHNRQKL 457
LN L+ + KL
Sbjct: 1252 NEELNLLKAQLNETLTKL 1269
Score = 49.7 bits (117), Expect = 1e-05
Identities = 103/500 (20%), Positives = 207/500 (41%), Gaps = 93/500 (18%)
Query: 57 EEKCKLLEKF---SLVQKEYEGYEVES-SLKNASFEKEATEAQ-------SLEATCEKLN 105
+EK K +E+ L+Q + E+ + +N+S KE + + S + E+L
Sbjct: 741 DEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELK 800
Query: 106 RFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDE----------SKSLKS 155
+ E +I +E+ L+ E K + + + + D+ + I++L++E S+ S
Sbjct: 801 KVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITS 860
Query: 156 QVAEAK--MTFKRFQANEERLEIE------------IQDAWKENSELQESQKQLLQEAEV 201
+V E + + K Q N + +E +QD +EN L+ +++ Q
Sbjct: 861 KVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLK 920
Query: 202 WKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKD----GVAMLEEDVTD 257
S+ FE+ ++ VL +KEN +K L E +LK ++ L +DV D
Sbjct: 921 EASSASQ-------FEELEI----VLKEKENELKRL-EAMLKERESDLSSKTQLLQDVQD 968
Query: 258 DDNL---ELEMNSESEDGAYLDNPPKGALKKLI--HAAKLNASLKTLEGERNQIYIQLSE 312
++ L ++E + PP L K+I +++ L+ ++ + Q +
Sbjct: 969 ENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKK 1028
Query: 313 VDKTKEELTEHIKNLQTEQASLQSENTHFESENQ---------------KLQQKLKVMTE 357
+ +E+ E ++ L + + LQ + E Q KL K+ V +
Sbjct: 1029 NNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSN 1088
Query: 358 LYQENEMKLYRKLIVE--------EKCRLEKEEKLSKVDEMISHATEELETYRKRAKD-- 407
L + + K E E+ ++ E KL + DEM + E E Y+ +
Sbjct: 1089 LSYGEWLHGFEKKAKECMAGTSGSEEVKV-LEHKLKEADEMHTLLQLECEKYKSVLAETE 1147
Query: 408 --LKEFEKTIHFYQKKIILHEKKAHDN----WSAAWTAERNLNDLRK-----ENAHNRQK 456
L++ ++++ + K + ++H S+ ++E+ L LR EN ++
Sbjct: 1148 GILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRRERE 1207
Query: 457 LTEIEFKIKLLEKDPYGLDV 476
E+E + +E+ Y +V
Sbjct: 1208 HLEMELEKAEMERSTYVTEV 1227
Score = 49.3 bits (116), Expect = 1e-05
Identities = 73/372 (19%), Positives = 160/372 (43%), Gaps = 44/372 (11%)
Query: 120 KELKEEKSKHSEQ-NELMADISKRIQSLEDESKSLKSQV----AEAKMTFKRFQANEERL 174
K+L +E E+ N ++ + RI +LE E ++++ E + +FQ E++
Sbjct: 356 KQLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQM 415
Query: 175 EIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKR---------TFEDSKVHAEQ 225
E EI +EN L+++ + E +Q +EL K ++ T + K+ E+
Sbjct: 416 EAEIAHLKQENGILRDAVSNTTNQLE--SKQSAELNKLRQDYARLVNELTEKTGKLQQEE 473
Query: 226 VLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKK 285
V K+N + T+ +++++ EE + + + + A D K K+
Sbjct: 474 V--QKKNAEQAATQLKVQLQEAERRWEEVQS-----YIRKRTAEHEAAQQDLQSKFVAKE 526
Query: 286 LIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESEN 345
L++ L + Q+ +L ++ +++++ ++LQ + + +N +++
Sbjct: 527 -NEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQI 585
Query: 346 QKLQQKLKVMT-------ELY-----QENEMKLYRKLIVEEKCRL-EKEEKLSKVDEM-- 390
Q+ ++ T EL+ ++ ++K + E+ RL KEE+L + M
Sbjct: 586 QQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNF 645
Query: 391 -ISHATEELETYRKR----AKDLKEFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLND 445
+ ++L+ A +L++ +++++ KI L E++ S + LND
Sbjct: 646 LLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILND 705
Query: 446 LRKENAHNRQKL 457
K QKL
Sbjct: 706 QNKALKSEVQKL 717
Score = 35.4 bits (80), Expect = 0.19
Identities = 32/174 (18%), Positives = 72/174 (41%), Gaps = 4/174 (2%)
Query: 85 ASFEKEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQ 144
+SF E + L + + + E H + LEK E + +E EL +++ +
Sbjct: 1180 SSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQK 1239
Query: 145 SLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKE 204
L+D Q E + + +L E + K +L ++Q+ L E+ +
Sbjct: 1240 KLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSL----ELIQS 1295
Query: 205 QVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDD 258
++ + E+S V E ++KE +L + + +++ + + + +T +
Sbjct: 1296 KIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKE 1349
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 79.7 bits (195), Expect = 9e-15
Identities = 65/346 (18%), Positives = 165/346 (47%), Gaps = 31/346 (8%)
Query: 119 EKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEI 178
+KEL+E++ + EQ E M + ++++ E++ + ++ E + K+ + E+++ +
Sbjct: 340 QKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE---KQMREQEQKMRDQE 396
Query: 179 QDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLT 238
+ W+++ L+E ++++ ++ ++W EQV ++ ++K+ E K +Q +K + +
Sbjct: 397 ERMWEQDERLREKEERMREQEKMW-EQVEKMREEKKMQEQEKKTRDQ--EEKMQEEERIR 453
Query: 239 ERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKT 298
ER KM++ + E + E + E+ + + ++L + +
Sbjct: 454 EREKKMREEEETMRE--------QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 505
Query: 299 LEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTEL 358
++ + +I+ Q ++ + +EE+ K + ++ + E+ +E E + Q+ K+
Sbjct: 506 MQEQEEKIWEQEEKI-RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW--- 561
Query: 359 YQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFY 418
+ E ++ +K +EK ++EEK+ E E R+R K ++E E+ +
Sbjct: 562 --DQEERMEKKTQEQEKKTWDQEEKM-----------REEERMREREKKMREEEEMMREQ 608
Query: 419 QKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKI 464
++K+ E+K + W E + + ++ +K+ E E K+
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM 654
Score = 76.3 bits (186), Expect = 1e-13
Identities = 94/481 (19%), Positives = 209/481 (43%), Gaps = 70/481 (14%)
Query: 43 RREKKFAVALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCE 102
R+EK+ L E++ +L E+ L ++E + E E EK + + + E
Sbjct: 318 RQEKRLREQEKELREQEKELREQKELREQEEQMQEQE--------EKMWEQEEKMREQEE 369
Query: 103 KLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEA-K 161
K+ R L + EK+++E++ K +Q E M + +R++ E+ + + + K
Sbjct: 370 KMWRQEERLWEQ----EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEK 425
Query: 162 MTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTF--EDS 219
M ++ +E+ + ++ +E ++E +K++ +E E +EQ ++ KQ+ ++
Sbjct: 426 MREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 485
Query: 220 KVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNL--------ELEMNSESED 271
K +Q L +++ + E++ + ++ + EE + D + + E E ED
Sbjct: 486 KEWQQQRLPEQKEKLWE-QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 544
Query: 272 GAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQ 331
+ ++ + + KT E E+ E + +E + E K ++ E+
Sbjct: 545 QMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTW--DQEEKMREEERMREREKKMREEE 602
Query: 332 ASLQSENTHFESENQKLQQKLKVM---TELYQENEMKLY---------------RKLIVE 373
++ + + + +K+Q++ + M E QE E K++ ++ + E
Sbjct: 603 EMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE 662
Query: 374 EKCRL-------------EKEEKLSKVDEMISHATE------------ELETYRKRAKDL 408
+K +L E+EEK+ + ++M E E E+ R+R K +
Sbjct: 663 QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKM 722
Query: 409 KEFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLE 468
+E E+ + ++K+ E+K + W E + + ++E +Q+L E + K+ E
Sbjct: 723 REEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWE-QEEKMWEQQRLPEQKEKLWEHE 781
Query: 469 K 469
K
Sbjct: 782 K 782
Score = 69.7 bits (169), Expect = 9e-12
Identities = 93/428 (21%), Positives = 182/428 (42%), Gaps = 37/428 (8%)
Query: 51 ALSGLIEEKCKLLEKFSLVQKEYEGYEVE---SSLKNASFEKEATEAQSLEATCEKLNRF 107
ALS + K + KE + +E +++ N +K+ E Q EKL
Sbjct: 184 ALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQ------EKLPLA 237
Query: 108 NSELVHEILCLEKELKE--EKSK----HSEQNELMADISKRIQSLEDESKSLKSQVAEAK 161
SE EI KELK E++K + N L ++ ++ + L ++ K ++ Q +
Sbjct: 238 ESEK-SEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMW 296
Query: 162 MTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQ--VSELIKQKRTFEDS 219
+R + E ++ + + W++ L+E +K+L ++ + +EQ + E +Q + E+
Sbjct: 297 RQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEK 356
Query: 220 KVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNS---ESEDGAYLD 276
E+ + ++E + ERL + + + E+ + D + E + E E+
Sbjct: 357 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ 416
Query: 277 NPPKGALKKLIHAAKLNASLKTL--EGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASL 334
++K+ K+ K + E+ Q ++ E +K E E ++ Q E+
Sbjct: 417 EKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMRE-QEEKMQK 475
Query: 335 QSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHA 394
Q EN + E + QQ+L E E E K+ +E+ E+EEK+ +EM
Sbjct: 476 QEENMWEQEEKEWQQQRLPEQKEKLWEQE-----KMQEQEEKIWEQEEKIRDQEEMWGQE 530
Query: 395 TE--ELETYRKRAKDLKEFEKTIHFYQKKI----ILHEKKAHDNWSAAWTAERNLNDLRK 448
+ E R++ + E E+ + ++K+ EKK + W E + + +
Sbjct: 531 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE--E 588
Query: 449 ENAHNRQK 456
E R+K
Sbjct: 589 ERMREREK 596
Score = 67.8 bits (164), Expect = 4e-11
Identities = 69/353 (19%), Positives = 159/353 (45%), Gaps = 29/353 (8%)
Query: 57 EEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEIL 116
EEK + E+ Q+E + + K ++E + EK R E++ E
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE-- 607
Query: 117 CLEKELKEEKSKHSEQNELMADISKRIQSLEDE--SKSLKSQVAEAKMTFKRFQANEERL 174
E++++E++ K EQ E M + +++Q E++ + K E KM ++RL
Sbjct: 608 -QEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW------EQQRL 660
Query: 175 EIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQ---KRTFEDSKVHAEQVLNDKE 231
+ + W E+ ++QE +K QE ++W+++ E Q K+T++ K+ E+ + ++E
Sbjct: 661 PEQKEKLW-EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRERE 719
Query: 232 NHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNS---ESEDGAYLDNPPKGALKKLIH 288
++ E + + ++ + EE + + + E E E+ + +KL
Sbjct: 720 KKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE 779
Query: 289 AAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKL 348
K+ E+ +I+ Q ++ +E++ + ++ ++ ++ + + +K+
Sbjct: 780 HEKMQ--------EQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831
Query: 349 ---QQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEEL 398
++K+ E E K+ K+ +E+ E+EEK+ +E + E++
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKM 884
Score = 66.6 bits (161), Expect = 8e-11
Identities = 94/468 (20%), Positives = 196/468 (41%), Gaps = 53/468 (11%)
Query: 42 VRREKKFAVALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATC 101
+R EKK +++ K+ E+ + ++E + E E +++ EK + +++
Sbjct: 426 MREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQE-EKMQKQEENMWEQE 484
Query: 102 EKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAK 161
EK E + L +KE E+ K EQ E + + ++I+ E+ K + K
Sbjct: 485 EK------EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 538
Query: 162 MTFKRFQA--NEERLEIEIQDAWKENSELQESQKQLLQEAEVW--------KEQVSELIK 211
M + Q EE++ + Q W + +++ ++ QE + W +E++ E K
Sbjct: 539 MREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQE--QEKKTWDQEEKMREEERMREREK 596
Query: 212 QKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESED 271
+ R E+ E+ + ++E ++ E++ + ++ + EE + + + E E E+
Sbjct: 597 KMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE----EKMWEQEE 652
Query: 272 GAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQ 331
+ +KL K+ K E E +I+ Q KT+E+ E+
Sbjct: 653 KMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEE-KIWEQEKMEKKTQEQ----------EK 701
Query: 332 ASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMI 391
+ E E ++ ++K++ E+ +E E K+ + EEK + ++EE + ++M
Sbjct: 702 KTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQ---EEKMQEQEEEMWEQEEKMW 758
Query: 392 SHATEELETYRKRAKDLKEFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENA 451
EE ++R + KE K+ HEK W E + D ++
Sbjct: 759 EQ--EEKMWEQQRLPEQKE----------KLWEHEKMQEQ--EKIWEQEEKMRDQEEKMR 804
Query: 452 HNRQKLTEIEFKIKLLEKDPYGLDVPNTAFGRQHSPYGPSPLGWPSSE 499
+K+ E K++ E+ +G + +G++ +G W E
Sbjct: 805 GQEEKMRGQEEKMRGQEEKMWGQE--EKMWGQEEKMWGQEEKMWGQEE 850
Score = 65.5 bits (158), Expect = 2e-10
Identities = 80/403 (19%), Positives = 182/403 (45%), Gaps = 41/403 (10%)
Query: 55 LIEEKCKLLEKFSLVQKEYEGYEVESSLKNASF-----------EKEATEAQSLEATCEK 103
L E+K KL E+ + ++E + +E E +++ EK + + EK
Sbjct: 493 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 552
Query: 104 LNRFNSELVHEILCLEKELKEEKSKHSEQNELMAD---ISKRIQSLEDESKSLKSQVAEA 160
+ ++ + +EK+ +E++ K +Q E M + + +R + + +E + ++ Q E
Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ--EE 610
Query: 161 KMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKR------ 214
KM Q EE+++ + + W++ ++QE ++++ ++ E EQ ++ +Q+R
Sbjct: 611 KM-----QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKE 665
Query: 215 -TFEDSKVHAEQVLNDKENHI-------KTLTERLLKMKDGVAMLEEDVTDDDNLELEMN 266
+E K+ ++ + ++E I K E+ K D M EE+ + E +M
Sbjct: 666 KLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRE--REKKMR 723
Query: 267 SESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKN 326
E E + + +K+ + + E+ + + + + KE+L EH K
Sbjct: 724 EEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 783
Query: 327 LQTEQASLQSENTHFESENQKLQ-QKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLS 385
+ E+ Q E + E + Q +K++ E + E K++ + EEK ++E+
Sbjct: 784 QEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQ---EEKMWGQEEKMWG 840
Query: 386 KVDEMISHATEELETYRKRAKDLKEFEKTIHFYQKKIILHEKK 428
+ ++M + E + + + ++E E+ + ++K+ E+K
Sbjct: 841 QEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEK 883
Score = 55.1 bits (131), Expect = 2e-07
Identities = 53/214 (24%), Positives = 96/214 (44%), Gaps = 19/214 (8%)
Query: 251 LEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQL 310
+EE + D L LE+ Y + LKK A+L L E E+++I + +
Sbjct: 199 IEELTKERDALSLEL--------YRNTITNEELKK--KNAELQEKLPLAESEKSEIQLNV 248
Query: 311 SEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKL 370
E+ + E + +QT +LQ E E E ++ ++K++ E E +L +
Sbjct: 249 KELKRKLERAKFLLPQVQTN--TLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQ- 305
Query: 371 IVEEKCRLEKEEKLSKVDEMISHATEELETYRKRA---KDLKEFEKTIHFYQKKIILHEK 427
E K R E+EEK+ + ++ + +EL K K+L+E E+ + ++K+ E+
Sbjct: 306 --EGKMR-EQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEE 362
Query: 428 KAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIE 461
K + W E L + K+ QK+ + E
Sbjct: 363 KMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 396
Score = 35.8 bits (81), Expect = 0.15
Identities = 28/185 (15%), Positives = 89/185 (48%), Gaps = 5/185 (2%)
Query: 61 KLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSEL--VHEILCL 118
K+ E+ S+ ++E + E E ++ EK + + ++ E++ ++ E +
Sbjct: 708 KMREEESMREREKKMREEEEMMREQE-EKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWE 766
Query: 119 EKELKEEKSKHSEQNELMAD--ISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEI 176
++ L E+K K E ++ I ++ + + D+ + ++ Q + + ++ + EE++
Sbjct: 767 QQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWG 826
Query: 177 EIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKT 236
+ + W + ++ ++++ + E +E++ ++ R E+ E+ + ++E ++
Sbjct: 827 QEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRG 886
Query: 237 LTERL 241
E++
Sbjct: 887 QEEKI 891
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 79.3 bits (194), Expect = 1e-14
Identities = 86/414 (20%), Positives = 187/414 (45%), Gaps = 19/414 (4%)
Query: 70 QKEYEGYEVESSLKNA-SFEKEATEAQSLEATCEK-LNRFNSELVHEILCLEKELKEEKS 127
Q E E ++ S L ++ F E +A S AT +K +R+ EL E L EL
Sbjct: 143 QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTI 202
Query: 128 KHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQA--NEERLEIEIQDAWKEN 185
E E A + +++Q +E E ++ V E K +R + +++L+ E KE
Sbjct: 203 TDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 262
Query: 186 SELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHA-EQVLNDKENHIKTLTERLLKM 244
+ + ++E E+W ++++ ++K ++ K+ E+ + ++E I+ E++ +
Sbjct: 263 QSVSAKLQAQVEENELWN-RLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQ 321
Query: 245 KDGVAMLEEDVTDDDNLELEMNS---ESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEG 301
++ + EE + + + E E E+ + + +K K+ K E
Sbjct: 322 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 381
Query: 302 ERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHF---ESENQKLQQKLKVMTEL 358
E +++ Q ++ + +E++ E + +Q ++ + + E E Q+ ++K++ E
Sbjct: 382 EA-KMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEK 440
Query: 359 YQENEMKLYRKLIVEEKCRLEKE---EKLSKVDEMISHATEELETYRKRAKDLKEFEKTI 415
+E E K+ + EEK R ++E E+ K+ E E+ +++ + ++ E+ I
Sbjct: 441 IREQEKKIREQ---EEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKI 497
Query: 416 HFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEK 469
+KKI E+K + E + + ++ +K+ E E K++ E+
Sbjct: 498 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 551
Score = 70.9 bits (172), Expect = 4e-12
Identities = 73/387 (18%), Positives = 184/387 (47%), Gaps = 39/387 (10%)
Query: 55 LIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEA----QSLEATCEKLNRFNSE 110
L E+ KL EK LV+ E E++ ++K + E + Q L+A + L +
Sbjct: 207 LKEKNAKLQEKLQLVESEKS--EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 264
Query: 111 LVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQA- 169
+ ++ +E + + +Q E M ++IQ E++ + + ++ E + +R +
Sbjct: 265 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEM 324
Query: 170 ---NEERLEIEIQDAWKENSELQESQKQLLQEAEV----WKEQVSELIK--QKRTFEDSK 220
EE++ + + W++ +++E ++++ ++ ++ K Q E I+ +KR +++K
Sbjct: 325 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384
Query: 221 V-HAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPP 279
+ E+ + ++E I+ E + + ++ + EE + + E EM + E
Sbjct: 385 MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQ---EEEMQEQEE--------- 432
Query: 280 KGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENT 339
K K+ K + + +I Q + + +E++ E + ++A +Q +
Sbjct: 433 ----KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488
Query: 340 HFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRL-EKEEKLSKVDEMISHATEEL 398
+ +K++++ K + E QE +++ +++ E++ ++ E+EEK+ + +E + E+
Sbjct: 489 KMRRQEEKIREQEKKIRE--QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ---EQE 543
Query: 399 ETYRKRAKDLKEFEKTIHFYQKKIILH 425
E R++ + ++E E + ++K+ H
Sbjct: 544 EKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 53.9 bits (128), Expect = 5e-07
Identities = 45/318 (14%), Positives = 145/318 (45%), Gaps = 33/318 (10%)
Query: 38 SRLYVRREKKFAVALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSL 97
+RL ++E+K + E + K+ E+ ++++ E + + EK + + +
Sbjct: 280 NRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 339
Query: 98 EATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLE--DESKSLKS 155
EK+ E +HE +++++E++ K E+ ++ ++ Q + + + ++
Sbjct: 340 WEKEEKIREL-EEKMHE----QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 394
Query: 156 QVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQK-- 213
Q + + + Q EE++ + + W++ E+QE ++++ ++ E +EQ ++ +Q+
Sbjct: 395 QEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEK 454
Query: 214 -RTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDG 272
R E+ E+ + ++E + ++ + ++ + EE + + E ++ + E
Sbjct: 455 IREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQ---EKKIREQEE-- 509
Query: 273 AYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQA 332
K+ + ++ + +++ Q ++ + +E++ E + ++ ++
Sbjct: 510 ------------------KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 551
Query: 333 SLQSENTHFESENQKLQQ 350
++ + + +K+Q+
Sbjct: 552 KMREQEVRLRQQEEKMQE 569
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 79.0 bits (193), Expect = 2e-14
Identities = 111/517 (21%), Positives = 211/517 (40%), Gaps = 106/517 (20%)
Query: 50 VALSGLIEEKCKLLEKFSLV-----------QKEYEGYEVESSLKNASFEKEATEAQSLE 98
+AL GL E+K KL+++ + Q++++ + E + S+E + EA+ ++
Sbjct: 1574 LALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQ 1633
Query: 99 ATCEKLNRFNSELVHEILCLE-------KELKEEKSKHSEQNELMADISK----RIQSLE 147
E + + EL ++ E K+L+E + + E E M +K +I LE
Sbjct: 1634 HVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELE 1693
Query: 148 DESKSLKSQVAEAKMTFKR-----------FQANEERLEIEIQDAWKENSELQESQKQLL 196
+E+ L+++V A T K + ER+++E + K+ L + L
Sbjct: 1694 EENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLS 1753
Query: 197 QEAEVWKEQVSELIKQKRTFEDSKVHAEQ------------------------------- 225
+E + K Q+ + ++ E ++ H Q
Sbjct: 1754 EEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSE 1813
Query: 226 -----------VLNDKENH--IKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDG 272
V D +H I +++ ++K+ +A LEE+ N E E+E
Sbjct: 1814 SVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEE--KQKNKEFSQTLENEKN 1871
Query: 273 AYLD--NPPKGALKKLIH-AAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQT 329
L + G LK L K+N + ++ E +++ ++ K++L E + N
Sbjct: 1872 TLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLA 1931
Query: 330 EQ-----------ASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRL 378
E Q +N ESE + L+ K ++EL +E + + K VE + R
Sbjct: 1932 ELNGSIGNYCQDVTDAQIKNELLESEMKNLK---KCVSELEEEKQQLVKEKTKVESEIRK 1988
Query: 379 EKEEKLS---KVDEMISHATEELETYRKRAKDLKEFEKTIHFYQKKIILHEKKAHDNWSA 435
E EK+ K SHA E E +++ +++K+ +K YQ+KI E+
Sbjct: 1989 EYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFV 2048
Query: 436 AWTAERNLNDLRKEN-----AHNRQKLTEI-EFKIKL 466
++++L ++ KEN H ++ E+ FK+ L
Sbjct: 2049 QTESQKDL-EITKENLAQAVEHRKKAQAELASFKVLL 2084
Score = 72.4 bits (176), Expect = 1e-12
Identities = 84/372 (22%), Positives = 164/372 (44%), Gaps = 41/372 (11%)
Query: 118 LEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKR-------FQAN 170
LE+ L++ + KH ++ + M + ++ +L E L+ + E ++T + Q N
Sbjct: 2123 LERRLEQAEEKHLKEKKNMQE---KLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEN 2179
Query: 171 EERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDK 230
+ ++ K S LQ+ + +++ EA+ W+ + S+ I+ K K VL D+
Sbjct: 2180 LDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQ 2239
Query: 231 ENHIKTLTERLLKMKDGVAMLEEDVTD-DDNLELEMNSESEDGAYLDNPPKGALKKLIHA 289
++ ++ + ++K ++ LE D + + E+ + + L K L +L
Sbjct: 2240 ---LRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEET 2296
Query: 290 AKLNAS----LKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ----TEQASLQSENTHF 341
L S L LE E + QL+++ + E+ E NL+ ++A +Q+ +
Sbjct: 2297 RHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSY 2356
Query: 342 ESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETY 401
E LQ ++ + L++E MK +K+I LS +E I A EL
Sbjct: 2357 EQLETDLQASRELTSRLHEEINMK-EQKII----------SLLSGKEEAIQVAIAELR-- 2403
Query: 402 RKRAKDLKEFEKTI-HFYQKKIILHE--KKAHDNWSAAWTAERNLNDLRKENAHNRQKLT 458
++ K++KE E + ++ I+L E KKA D + L ++KEN + +L
Sbjct: 2404 QQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLM---ETLKTIKKENIQQKAQLD 2460
Query: 459 EIEFKIKLLEKD 470
+ L+ D
Sbjct: 2461 SFVKSMSSLQND 2472
Score = 66.2 bits (160), Expect = 1e-10
Identities = 126/554 (22%), Positives = 223/554 (40%), Gaps = 136/554 (24%)
Query: 45 EKKFAVALSG------LIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEA------T 92
E+KF+ A+ L E+ C +L K L Q E++ ++ +K+ T
Sbjct: 2212 ERKFSDAIQSKEEEIRLKEDNCSVL-KDQLRQMSIHMEELKINISRLEHDKQIWESKAQT 2270
Query: 93 EAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSK-HSEQNELMADISKRIQSLEDESK 151
E Q + C+ L N EL+ +L+E + HS QNEL LE E K
Sbjct: 2271 EVQLQQKVCDTLQGENKELL-------SQLEETRHLYHSSQNELA--------KLESELK 2315
Query: 152 SLKSQVAEAKMTFKRFQANEERLE--IEIQDAWKENSELQESQKQLLQEAEVWKEQVSEL 209
SLK Q+ + + ++ + + LE I Q+A +NS+ S +QL + + +E S L
Sbjct: 2316 SLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKF--SYEQLETDLQASRELTSRL 2373
Query: 210 IKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDG-VAMLEEDVTDDDNLELEMNSE 268
++ E + +L+ KE I+ L + D + LE ++ ++ + + E
Sbjct: 2374 HEEINMKEQKII---SLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEE 2430
Query: 269 SEDGAYLDNPPKGALK-----KLIHAAKLNA---SLKTLEGERNQI---YIQL------- 310
++ N LK + A+L++ S+ +L+ +R++I Y QL
Sbjct: 2431 NKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSI 2490
Query: 311 ------------SEVDKTKEE---LTEHIKNLQTEQASLQSENTHFESE-NQKL-----Q 349
+E +K KEE L H+ +L +E A L +E + + NQ + Q
Sbjct: 2491 ILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQ 2550
Query: 350 QKLKVMTELYQENEMK-LYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDL 408
QK + +L Q E++ Y KL EEK + E EE + + EE + K + L
Sbjct: 2551 QKQLLEVQLQQNKELENKYAKL--EEKLK-ESEEANEDLRRSFNALQEEKQDLSKEIESL 2607
Query: 409 K-------------EFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKE------ 449
K + E T+ Y ++ + E++ H + ++++ + +L +E
Sbjct: 2608 KVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQK 2667
Query: 450 --------------------------------NAHNR-----QKLTEIEFKIKLLEKDPY 472
A R + L E+E K+ ++ K+
Sbjct: 2668 EAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENK 2727
Query: 473 GLDVPNTAFGRQHS 486
GL +FGR S
Sbjct: 2728 GLTAQIQSFGRSMS 2741
Score = 61.2 bits (147), Expect = 3e-09
Identities = 108/474 (22%), Positives = 195/474 (41%), Gaps = 80/474 (16%)
Query: 35 SVTSRLYVRREKKFAVALSGLIEEKCKLLE---KFSLVQKEYEGYEVESSLKNASFEKEA 91
S T R V +K+ + KC+ +E K ++ +KE E + L+ EK A
Sbjct: 1030 SETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLE----EKLA 1085
Query: 92 TEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKS---------KHSEQNELMA----- 137
E Q +A +++N+ + ++I L+ E+ E ++ + + +A
Sbjct: 1086 AEEQ-FQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKET 1144
Query: 138 ----------------DISKRIQSLEDESKSLKSQVAEA----KMTFKRFQANEERLEIE 177
++ ++I +LE E + L+ ++ EA K K+ Q E L E
Sbjct: 1145 VVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREE 1204
Query: 178 IQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKT- 236
++ + + LQE + +E E +Q+ +L Q R D K+ + + +E+ T
Sbjct: 1205 LKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPS---TDQQESCSSTP 1261
Query: 237 -LTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNAS 295
L E L K + + NL + S SED + AL+ A++ A
Sbjct: 1262 GLEEPLFKATE---QHHTQPVLESNLCPDWPSHSEDAS--------ALQGGTSVAQIKAQ 1310
Query: 296 LKTLEGERNQIYIQL----SEVDKTKEE---LTEHIKNLQTEQASLQSENTHFESENQKL 348
LK +E E+ ++ +++ SE+ K EE L E I E SL++ + E + L
Sbjct: 1311 LKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESL 1370
Query: 349 QQKLK--VMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAK 406
QQKL+ + E+ +L KL +K +KEE +S + +S L +
Sbjct: 1371 QQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEII 1430
Query: 407 DLKEFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEI 460
+ ++ K +H + + K HD + L+ E +QK EI
Sbjct: 1431 EQEDLIKALHTQLEM----QAKEHD---------ERIKQLQVELCEMKQKPEEI 1471
Score = 57.4 bits (137), Expect = 5e-08
Identities = 86/423 (20%), Positives = 165/423 (39%), Gaps = 57/423 (13%)
Query: 72 EYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSE 131
+YE +L + EA+S + E L+ EL + + + SE
Sbjct: 783 DYESQTAHDNLLTEQIHSLSIEAKSKDVKIE--------------VLQNELDDVQLQFSE 828
Query: 132 QNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQES 191
Q+ L I+SL+ + ++ +S+V E + + E L + E +++ +
Sbjct: 829 QSTL-------IRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQL 881
Query: 192 QKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKE----NHIKTLTERLLKMKDG 247
+ ++ E ++ + E +Q S LN+++ IKTL E+L +
Sbjct: 882 LLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRA 941
Query: 248 VAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIY 307
+E V +D+ + + Y + P G + K +L L+ E Q
Sbjct: 942 EEAKKEQVEEDNEVSSGLKQN-----YDEMSPAGQISK----EELQHEFDLLKKENEQRK 992
Query: 308 IQLSEVDKTKEELTEHIKNLQTEQASL-----------QSENTHFESENQKLQQKLKVMT 356
+L ++EL + + L+ E A+L ++E E + + + K +T
Sbjct: 993 RKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVT 1052
Query: 357 ELYQENEMKLYRKLIVEEK------CRLEKEEKLSKVDEMISHATEELETYRKRAKDLKE 410
Q E+++Y K + EK R + EEKL+ ++ + + +T + + +
Sbjct: 1053 SKCQ--EIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDL 1110
Query: 411 FEKTIHFYQ---KKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLL 467
+ I Q +K+I A D S A E + + K E+E KI L
Sbjct: 1111 LQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWK-PELEEKILAL 1169
Query: 468 EKD 470
EK+
Sbjct: 1170 EKE 1172
Score = 55.8 bits (133), Expect = 1e-07
Identities = 78/404 (19%), Positives = 158/404 (39%), Gaps = 56/404 (13%)
Query: 52 LSGLIEEK--------CKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEK 103
LSG + EK +++E+ L++ + E+++ + ++ E ++ E+
Sbjct: 1411 LSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEE 1470
Query: 104 LN-------RFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQ 156
+ + +L ++ ++ LKE KS E + I + +SL D + +Q
Sbjct: 1471 IGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQ 1530
Query: 157 VAEAKMTFKRF---QANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQK 213
E R Q ++L E+ + EN L S + L E E +L+K+
Sbjct: 1531 NKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEI 1590
Query: 214 RTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGA 273
+ + SK+ +K ++ E LL+ + V+ E + ++ + E ++
Sbjct: 1591 ESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERI---QHVVEAVRQEKQE-- 1645
Query: 274 YLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHI----KNLQT 329
L L++ E + + QL E ++ EE+ E + K+ Q
Sbjct: 1646 ------------------LYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQ 1687
Query: 330 EQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDE 389
+ L+ EN +E K E + + +L E+ ++E E K
Sbjct: 1688 KILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEEL---ERVKMEYETLSKKFQS 1744
Query: 390 MISHATEELETYRKRAKDLK-EFEKTIHFYQKKIILHEKKAHDN 432
++S E ++ + +DLK + E + K+ L + HDN
Sbjct: 1745 LMS----EKDSLSEEVQDLKHQIEGNV---SKQANLEATEKHDN 1781
Score = 55.8 bits (133), Expect = 1e-07
Identities = 80/400 (20%), Positives = 160/400 (40%), Gaps = 67/400 (16%)
Query: 49 AVALSGLIEEKCKLLEKFS--LVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNR 106
A +++ E LEK + L+ K+ + + S L E + QS L
Sbjct: 2789 AFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQL-----EDSYNQVQSFSKAMASLQN 2843
Query: 107 FNSELVHEILCLEKELKEEKSKH------SEQNELMADISKRIQSLEDESKSLKSQVAEA 160
L +E LEK K E+ K S + + K + SL+++ L ++
Sbjct: 2844 ERDHLWNE---LEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNL 2900
Query: 161 KMTFKRFQANEERLEI-----EIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRT 215
+ + Q N+E E+ ++Q+ + Q Q++L QE W+ ++ +L +K +
Sbjct: 2901 QQQY--LQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSS 2958
Query: 216 FEDSKVHAEQ----VLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESED 271
+E + ++ ++DK+ + L + +++ + + S S D
Sbjct: 2959 WEIHERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPD 3018
Query: 272 GAY------------LDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEE 319
G+ L++ K +K + +LN++ L E+N + IQL + ++ E
Sbjct: 3019 GSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRE 3078
Query: 320 LTEHIKNLQTEQASLQSE----------------------NTHFESENQKLQQKLKVMTE 357
+H +L A L+ + H +S+ ++L++ + +E
Sbjct: 3079 NQQHYGDLLNHCAVLEKQVQELQAGPLNIDVAPGAPQEKNGVHRKSDPEELREPQQSFSE 3138
Query: 358 LYQE-----NEMKLYRKLIVEEK-CRLEKEEKLSKVDEMI 391
Q+ E+ RKL+ EE+ R+ E LS +E I
Sbjct: 3139 AQQQLCNTRQEVNELRKLLEEERDQRVAAENALSVAEEQI 3178
Score = 55.5 bits (132), Expect = 2e-07
Identities = 77/362 (21%), Positives = 152/362 (41%), Gaps = 81/362 (22%)
Query: 79 ESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMAD 138
ESSL E+ +TE QS T E+++ ++ + ELK K + + D
Sbjct: 629 ESSLPAVEKEQASTEHQS--RTSEEISLNDAGV---------ELKSTKQDGDKSLSAVPD 677
Query: 139 ISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQE 198
I Q +DE + LKSQ+ E ++ F + Q E+ L E K++
Sbjct: 678 IG---QCHQDELERLKSQILELELNFHKAQEIYEK-------------NLDEKAKEI--- 718
Query: 199 AEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDD 258
+++LI++ + D+ A L+++ + + + + L + + A ++
Sbjct: 719 -----SNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVK------ 767
Query: 259 DNLELEMN-SESEDGAYLDNPPKGA----LKKLIHAAKLNA-----SLKTLEGERNQIYI 308
+LEMN +E+E LD + A L + IH+ + A ++ L+ E + + +
Sbjct: 768 ---QLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQL 824
Query: 309 QLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYR 368
Q SE L ++N ++E H S+ ++L Q L
Sbjct: 825 QFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALS--------------- 869
Query: 369 KLIVEEKCRLEKEEKLSKVDEMISHATEELETYRK--RAKDLKEFEKTIHFYQKKIILHE 426
+KE +++K+D+++ ++ET ++ KD + E + +K + L+E
Sbjct: 870 ----------QKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNE 919
Query: 427 KK 428
+K
Sbjct: 920 EK 921
Score = 55.1 bits (131), Expect = 2e-07
Identities = 78/383 (20%), Positives = 167/383 (43%), Gaps = 55/383 (14%)
Query: 77 EVESSLKNASFEKEATEAQS----LEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQ 132
E+ S+ N + ++ T+AQ LE+ + L + SEL E +++L +EK+K +
Sbjct: 1932 ELNGSIGN--YCQDVTDAQIKNELLESEMKNLKKCVSELEEE----KQQLVKEKTK--VE 1983
Query: 133 NELMADISKRIQSLEDE------SKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENS 186
+E+ + ++IQ + E +K L+ + E + K+ Q + R + +I +
Sbjct: 1984 SEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2043
Query: 187 ELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKD 246
L+ Q + ++ E+ KE +++ ++ ++ + + +L+D ++ + LK+K
Sbjct: 2044 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKK 2103
Query: 247 GVAMLEEDVTD-----DDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEG 301
+ +E V D++LE + E K +KL + L+ G
Sbjct: 2104 ELQSNKESVKSQMKQKDEDLERRLEQAEEKHL---KEKKNMQEKLDALRREKVHLEETIG 2160
Query: 302 ERNQIYIQLSEVDKTKEELTEHIKNLQTEQA-------SLQSENTHFESENQKLQQKLKV 354
E I + L++ DK ++L E++ + T+ A SLQ + E +K ++K
Sbjct: 2161 E---IQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSD 2217
Query: 355 MTELYQE----------------NEMKLYRKLIVEEKCRLEKEEKL--SKVDEMISHATE 396
+ +E +M ++ + + RLE ++++ SK + +
Sbjct: 2218 AIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQK 2277
Query: 397 ELETYRKRAKD-LKEFEKTIHFY 418
+T + K+ L + E+T H Y
Sbjct: 2278 VCDTLQGENKELLSQLEETRHLY 2300
Score = 53.5 bits (127), Expect = 7e-07
Identities = 81/378 (21%), Positives = 158/378 (41%), Gaps = 42/378 (11%)
Query: 89 KEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLED 148
K++ + Q LE ++ N EL ++ LE++LKE + + + + + Q L
Sbjct: 2547 KDSQQKQLLEVQLQQ----NKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSK 2602
Query: 149 ESKSLKSQVAEAKMTFKRFQAN------EERLEIEIQDAWKENSELQESQKQLLQEAE-- 200
E +SLK +++ Q +L+++ ++ + ++ SQK++ + E
Sbjct: 2603 EIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEEL 2662
Query: 201 --VWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDV--- 255
V KE ++ + + + H N +T ER+ ++ + +E+ +
Sbjct: 2663 VCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMV 2722
Query: 256 -TDDDNLELEMNSESEDGAYLDNPPKGALKKLIH-AAKLNASLKTLEGERNQIYIQ---- 309
++ L ++ S + L N A ++L K +ASLK L + Q +
Sbjct: 2723 TKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERD 2782
Query: 310 --LSE----VDKTKEELTEHIKNLQTEQASLQSENTHFESENQ----KLQQKLKVMTELY 359
LSE ++ T+E H++ L + S + H S+ + ++Q K M L
Sbjct: 2783 ALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQ 2842
Query: 360 QE-----NEMKLYRKLIVEEKCRLEKEEKLSKVD-EMISHATEELETYRKR-AKDLKEFE 412
E NE++ +RK E K R + S + + + A L+ R R K+LK +
Sbjct: 2843 NERDHLWNELEKFRK-SEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQ 2901
Query: 413 KT-IHFYQKKIILHEKKA 429
+ + Q+ LH KA
Sbjct: 2902 QQYLQINQEITELHPLKA 2919
Score = 46.6 bits (109), Expect = 8e-05
Identities = 91/471 (19%), Positives = 184/471 (39%), Gaps = 53/471 (11%)
Query: 46 KKFAVALSGLIEEK-CKLLEKFSLVQKEYEGYE-------VESSLKNASFEKEATEAQSL 97
++ V L +I +K +L +K +Q+E + + + + K S K E ++
Sbjct: 58 EQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQ 117
Query: 98 EATCEKLNRFNSELV--HEILCLEKELKEEKSKHS--EQNELMADISKRIQSLEDESKSL 153
T + E + H+ E+E++ EK KH E+ EL++ + ++ + E +
Sbjct: 118 GGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQ 177
Query: 154 KSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSEL---- 209
S E + K+ Q E+ I A ++ +++ +Q+++E + E L
Sbjct: 178 SSTEMEEFVMMKQ-QLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDE 236
Query: 210 IKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDN--------- 260
+ Q T D + +Q L + ++ E L+ V +L++++T +
Sbjct: 237 LLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQL 296
Query: 261 --LELEMNSESEDGAYLDNPPKGALKKL-IHAAKLNASLKTLEGERNQIYIQLSEVDKTK 317
+E E N+ K L+K+ + A+ S L+ E + + Q + + +
Sbjct: 297 QQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQ 356
Query: 318 EEL------------------TEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELY 359
EL T HI +LQ LQS + +N KL Q
Sbjct: 357 AELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQS 416
Query: 360 QENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFYQ 419
+ +L +L + K + +L + T + Y + + + E+ I Q
Sbjct: 417 AQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVT--EENIASLQ 474
Query: 420 KKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKD 470
K+++ E + A + L +L+ EN ++T +E + + E D
Sbjct: 475 KRVVELENEK----GALLLSSIELEELKAENEKLSSQITLLEAQNRTGEAD 521
Score = 42.4 bits (98), Expect = 0.002
Identities = 68/339 (20%), Positives = 144/339 (42%), Gaps = 18/339 (5%)
Query: 90 EATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDE 149
E Q L KL LV ++ L++E + ++N+++ S+++Q +E E
Sbjct: 247 ETEMQQKLRVLQRKLEEHEESLVGRAQVVDL-LQQELTAAEQRNQIL---SQQLQQMEAE 302
Query: 150 SKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSEL 209
+L++ V + K E++E+E+ + LQE LL++ E + +EL
Sbjct: 303 HNTLRNTVETEREESKILL---EKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAEL 359
Query: 210 IKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSES 269
+ E K AE + +K +HI +L + +++ L++ + L + N ++
Sbjct: 360 ESRYSALEQ-KHKAE--MEEKTSHILSLQKTGQELQSACDALKDQ---NSKLLQDKNEQA 413
Query: 270 EDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQT 329
A + L++ + +++ L L ++++ Q S D E T+ + +
Sbjct: 414 VQSAQTIQQLEDQLQQ--KSKEISQFLNRLPLQQHETASQTSFPDVYNEG-TQAVT--EE 468
Query: 330 EQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDE 389
ASLQ E+E L + EL ENE + ++E + R + ++
Sbjct: 469 NIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEIS 528
Query: 390 MISHATEELETYRKRAKDLKEFEKTIHFYQKKIILHEKK 428
++ A + + + +D+ E + + ++L E K
Sbjct: 529 IVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMK 567
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 78.6 bits (192), Expect = 2e-14
Identities = 106/425 (24%), Positives = 181/425 (42%), Gaps = 65/425 (15%)
Query: 77 EVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELM 136
E E K+ K + +E E++ R + +L+ E L ++L+ E +E E+
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910
Query: 137 ADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLL 196
A ++ + Q LE+ L+S+V E + + Q +++++ IQD +E + +E +Q L
Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDL-EEQLDEEEGARQKL 969
Query: 197 Q------EAEVWK---------EQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERL 241
Q EA++ K +Q S+ IK+K+ ED L ++E K L +
Sbjct: 970 QLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIR 1029
Query: 242 LKMKDGVAMLEEDVTDDDNL--ELEMNSESEDGAYLDNPPKGA-LKKLIHAAKLNASLKT 298
K + ++ LEE + ++ ELE DG D + A L+ I KL + K
Sbjct: 1030 NKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKK- 1088
Query: 299 LEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTEL 358
E E + + K + ++ LQ + A LQ + FESE + K +L
Sbjct: 1089 -EEELQGALARGDDETLHKNNALKVVRELQAQIAELQED---FESEKASRNKAEKQKRDL 1144
Query: 359 YQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFY 418
+E E + E E+ L + A +EL T KR +++ E
Sbjct: 1145 SEE-----------LEALKTELEDTLD-----TTAAQQELRT--KREQEVAEL------- 1179
Query: 419 QKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTE-----IEFKIKLLEKDPYG 473
KK + E K H E + D+R+ +A ++L+E FK LEK+ G
Sbjct: 1180 -KKALEEETKNH---------EAQIQDMRQRHATALEELSEQLEQAKRFKAN-LEKNKQG 1228
Query: 474 LDVPN 478
L+ N
Sbjct: 1229 LETDN 1233
Score = 76.3 bits (186), Expect = 1e-13
Identities = 83/441 (18%), Positives = 184/441 (41%), Gaps = 46/441 (10%)
Query: 89 KEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLED 148
K E ++ E+ + + + LE +L++ + E+ ++S RI+ LE+
Sbjct: 1284 KLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEE 1343
Query: 149 ESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSE-------LQESQKQLLQEAEV 201
E SL+ Q E + K + L+ ++ D K+ + L+E++K+LL++AE
Sbjct: 1344 EKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEA 1403
Query: 202 WKEQVSELIKQKRTFEDSKVHAEQVLN------DKENHIKTLTERLLKMKDGVAMLEEDV 255
+++ E E +K +Q L+ D + + + E+ K D + E+ +
Sbjct: 1404 LSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSI 1463
Query: 256 T-----DDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAK----LNASLKTLEGERNQI 306
+ + D E E + L + AL+ + L A ++ L ++ +
Sbjct: 1464 SARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDV 1523
Query: 307 YIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQ------ 360
+ E++K+K L + ++ ++T+ L+ E E +L+ ++ M ++
Sbjct: 1524 GKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTR 1583
Query: 361 ----ENEMKLYRKLIVEEKCRLEKEEK--------LSKVDEMISHATEELETYRKR---- 404
E + +L K + E + LE E K K++ + ++E K
Sbjct: 1584 DEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEV 1643
Query: 405 AKDLKEFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKI 464
K L++ + + YQ+++ + ++ + +E+ L L E +++L E
Sbjct: 1644 IKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERAR 1703
Query: 465 KLL--EKDPYGLDVPNTAFGR 483
+ E+D ++ N+A G+
Sbjct: 1704 RHAEQERDELADEITNSASGK 1724
Score = 69.7 bits (169), Expect = 9e-12
Identities = 107/487 (21%), Positives = 206/487 (42%), Gaps = 70/487 (14%)
Query: 30 WRSFRSVTSRLYVRREKKFAVALSGLIEEKCKLLEKFSLVQKEYEGYE-------VESSL 82
WR F V L V R+++ L EE K+ EK + V+ E E E E ++
Sbjct: 835 WRVFTKVKPLLQVTRQEE---ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNI 891
Query: 83 KNASFEKEA---TEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADI 139
+ E EA+ + A + E++H+ LE ++EE+ E+N+++ +
Sbjct: 892 LAEQLQAETELFAEAEEMRARLAAKKQELEEILHD---LESRVEEEE----ERNQILQNE 944
Query: 140 SKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEA 199
K++Q+ + L+ Q+ E + ++ Q + E +I+ +E L++ + ++E
Sbjct: 945 KKKMQA---HIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEK 1001
Query: 200 EVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLK---------------- 243
++ +++++E Q E+ + ++ N +E I L ERL K
Sbjct: 1002 KLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLD 1061
Query: 244 -----MKDGVAMLEEDVTDDDNLELEMNSESEDGAYL--DNPPKGALKKLIHAAKLNASL 296
++D +A L+ + D+ L+L E GA D+ L +L A +
Sbjct: 1062 GETTDLQDQIAELQAQI-DELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQI 1120
Query: 297 KTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTE-------QASLQSENTHFESENQKLQ 349
L+ + ++ +K K +L+E ++ L+TE A+ Q T E E +L+
Sbjct: 1121 AELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELK 1180
Query: 350 QKLKVMTELY--QENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRK---- 403
+ L+ T+ + Q +M+ +EE E+ E+ + + + LET K
Sbjct: 1181 KALEEETKNHEAQIQDMRQRHATALEELS--EQLEQAKRFKANLEKNKQGLETDNKELAC 1238
Query: 404 RAKDLKEFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKL-TEIEF 462
K L++ + +KK+ ++ H S + LR E A KL E++
Sbjct: 1239 EVKVLQQVKAESEHKRKKLDAQVQELHAKVSEG-------DRLRVELAEKASKLQNELDN 1291
Query: 463 KIKLLEK 469
LLE+
Sbjct: 1292 VSTLLEE 1298
Score = 67.8 bits (164), Expect = 4e-11
Identities = 102/452 (22%), Positives = 182/452 (40%), Gaps = 74/452 (16%)
Query: 47 KFAVALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNR 106
K A ALS +EEK +K ++K + E + + A +LE +K +
Sbjct: 1399 KDAEALSQRLEEKALAYDK---LEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFD- 1454
Query: 107 FNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLK-----SQVAEAK 161
++L EK + ++ ++ E ++ E E+K+L + EAK
Sbjct: 1455 -------QLLAEEKSISARYAEERDRAEA--------EAREKETKALSLARALEEALEAK 1499
Query: 162 MTFKR----FQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFE 217
F+R +A+ E L D K EL++S++ L Q+ E + Q+ EL + + E
Sbjct: 1500 EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1559
Query: 218 DSKVHAEQVL-------------NDKENH------IKTLTERLLKMKD-----GVAMLEE 253
D+K+ E + D++N IK + E +++D +A+ +
Sbjct: 1560 DAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASK 1619
Query: 254 DVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEV 313
+ D +LE E+ + A D K K L+ R++I+ Q E
Sbjct: 1620 KKMEIDLKDLEAQIEAANKA-RDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES 1678
Query: 314 DKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVE 373
+K + L I LQ E AS + H E E +L ++ + +++
Sbjct: 1679 EKKLKSLEAEILQLQEELASSERARRHAEQERDELADEI---------TNSASGKSALLD 1729
Query: 374 EKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKEFEKTIHFYQKKIILHEKKAHDNW 433
EK RL E ++++++E + +E R F KT Q + E A
Sbjct: 1730 EKRRL--EARIAQLEEELEEEQSNMELLNDR------FRKTT--LQVDTLNAELAAER-- 1777
Query: 434 SAAWTAERNLNDLRKENAHNRQKLTEIEFKIK 465
SAA ++ L ++N + KL E+E +K
Sbjct: 1778 SAAQKSDNARQQLERQNKELKAKLQELEGAVK 1809
Score = 65.9 bits (159), Expect = 1e-10
Identities = 107/483 (22%), Positives = 186/483 (38%), Gaps = 78/483 (16%)
Query: 38 SRLYVRREKKFAVALSGLIEEKCKLLE----KFSLVQKEYEGYEVESSLKNASFEKEATE 93
+R ++ EK A A +EE+ LLE KF +K E E S + A E++A
Sbjct: 965 ARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKN 1024
Query: 94 AQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSL 153
+ E + I LE+ LK+E+ E + + L+D+ L
Sbjct: 1025 LAKIRNKQEVM----------ISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAEL 1074
Query: 154 KSQVAEAKMTFKRFQANEERLE----------IEIQDAWKENSELQESQKQLLQEAEVWK 203
++Q+ E K+ + EE L+ + +A K ELQ +L ++ E K
Sbjct: 1075 QAQIDELKLQLAK---KEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEK 1131
Query: 204 EQVSELIKQKRTFEDS----KVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDD 259
++ KQKR + K E L+ + T+R ++ + LEE+ + +
Sbjct: 1132 ASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHE 1191
Query: 260 NLELEMN------------------------SESEDGAYLDNPPKGALKKLIHAAKLNA- 294
+M +++ G DN K++ K +
Sbjct: 1192 AQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESE 1251
Query: 295 -SLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASL-------QSENTHFESENQ 346
K L+ + +++ ++SE D+ + EL E LQ E ++ + + F +
Sbjct: 1252 HKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAA 1311
Query: 347 KLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAK 406
L+ +L+ EL QE + +KL + + R +EEK S + EE E R
Sbjct: 1312 SLESQLQDTQELLQE---ETRQKLNLSSRIRQLEEEKNS-----LQEQQEEEEEAR---- 1359
Query: 407 DLKEFEKTIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKL 466
K EK + Q ++ +KK D+ + E L K+ Q+L E
Sbjct: 1360 --KNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDK 1417
Query: 467 LEK 469
LEK
Sbjct: 1418 LEK 1420
Score = 42.0 bits (97), Expect = 0.002
Identities = 42/204 (20%), Positives = 86/204 (42%), Gaps = 15/204 (7%)
Query: 53 SGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELV 112
S L++EK +L + + +++E E + L N F K + +L A +
Sbjct: 1725 SALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSD 1784
Query: 113 HEILCLEKELKEEKSKHSE-----QNELMADISK---RIQSLEDESKSLKSQVAEAKMTF 164
+ LE++ KE K+K E +++ A IS +I LE++ + + A A
Sbjct: 1785 NARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLV 1844
Query: 165 KRFQANEERLEIEIQDAWKENSELQES-------QKQLLQEAEVWKEQVSELIKQKRTFE 217
+R + + + ++++D + + +E KQL ++ E +E+ + +R +
Sbjct: 1845 RRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQ 1904
Query: 218 DSKVHAEQVLNDKENHIKTLTERL 241
A + + TL RL
Sbjct: 1905 RELDDATEANEGLSREVSTLKNRL 1928
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 78.6 bits (192), Expect = 2e-14
Identities = 95/415 (22%), Positives = 170/415 (40%), Gaps = 75/415 (18%)
Query: 59 KCKLLEKFSLVQKEYEGYEVESSLKNASFEK--------------------EATEAQSLE 98
K KLL++ + ++KE E +E S K F E + + +E
Sbjct: 971 KKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIE 1030
Query: 99 ATCE---------------KLNRFNSEL--VHEILCLEKELKEEKSKHS------EQNEL 135
+ E KLN+ EL +HEI EKE + + K E+ E+
Sbjct: 1031 SLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEM 1090
Query: 136 MADIS----------KRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKEN 185
+I+ + L+++ K + V + +A+ E+LE+++ + KEN
Sbjct: 1091 NKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKEN 1150
Query: 186 SELQESQKQLLQEAEVWKEQVSELIKQKRTFED-------SKVHAEQVLNDKENHIKTLT 238
+ LQE +L AE K +VSEL + +T ++ S + + L DK K L+
Sbjct: 1151 TFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLS 1210
Query: 239 ERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLD----------NPPKGALKKLIH 288
E L D E + + EL S S+ A L + L K
Sbjct: 1211 EELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCT 1270
Query: 289 AAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKL 348
++L A L+ L E+N + I + EE IK+++ + SL +E + E
Sbjct: 1271 VSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQ 1330
Query: 349 QQ----KLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELE 399
QQ K +T+L +E + +++E+ + EK+ ++S + + ++ +L+
Sbjct: 1331 QQAASEKESCITQLKKELSENINAVTLMKEELK-EKKVEISSLSKQLTDLNVQLQ 1384
Score = 73.6 bits (179), Expect = 6e-13
Identities = 94/450 (20%), Positives = 208/450 (46%), Gaps = 45/450 (10%)
Query: 29 LWRSFRSVTSRLYVRREKKFAVALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFE 88
L R + +T +L R E++F + +E+ K S +++ E +L+ +
Sbjct: 489 LARKEQELTKKLQTR-EREFQEQMKVALEKSQSEYLKISQEKEQQESL----ALEELELQ 543
Query: 89 KEA--TEAQS-LEATCEKLNRFNSELVHEILCLEKELKEEKSK--------HSEQNELMA 137
K+A TE+++ L ++ + + ++ LEK L+E K++ +E+N+
Sbjct: 544 KKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNK 603
Query: 138 DISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQ 197
+I+ ++ + E +SLK Q + + ++ Q +++ + E++ K + ++ ++ LL+
Sbjct: 604 EITVMVEKHKTELESLKHQ--QDALWTEKLQVLKQQYQTEME---KLREKCEQEKETLLK 658
Query: 198 EAEV-WKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVT 256
+ E+ ++ + E+ ++T E V + L + + + + K+++ +++L+ D T
Sbjct: 659 DKEIIFQAHIEEM--NEKTLEKLDVKQTE-LESLSSELSEVLKARHKLEEELSVLK-DQT 714
Query: 257 DDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKT 316
D ELE + + + +K+ H + + K L+ + NQ+ + L E DK
Sbjct: 715 DKMKQELEAKMDEQKNHH-QQQVDSIIKE--HEVSIQRTEKALKDQINQLELLLKERDKH 771
Query: 317 KEELTEHIKNLQTE----QASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIV 372
+E H++NL+ + + LQ + + Q Q T+ Y+E +L +KL+
Sbjct: 772 LKEHQAHVENLEADIKRSEGELQQASAKLD-VFQSYQSATHEQTKAYEEQLAQLQQKLLD 830
Query: 373 EEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDL-KEFEKTIHFYQKKIILHEKKAHD 431
E R+ +++++V+ EL+ ++ + +DL ++ EK ++K+
Sbjct: 831 LETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKV--------- 881
Query: 432 NWSAAWTAERNLNDLRKENAHNRQKLTEIE 461
S E L D KE +Q L E E
Sbjct: 882 -KSLTQVYESKLEDGNKEQEQTKQILVEKE 910
Score = 61.6 bits (148), Expect = 3e-09
Identities = 88/395 (22%), Positives = 166/395 (42%), Gaps = 67/395 (16%)
Query: 77 EVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELM 136
E + + A+FE+ + + T E + +E+ +I +EK +EE+ L
Sbjct: 403 EQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERIS------LQ 456
Query: 137 ADISKRIQSLEDE-SKSLKSQVAEA-KMTFKRFQANEERLEIEIQDAWKENSE-----LQ 189
++S+ Q + D KS + Q+A+ K+ K E+ L ++Q +E E L+
Sbjct: 457 QELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALE 516
Query: 190 ESQKQLLQEAEVWKEQVS----ELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMK 245
+SQ + L+ ++ ++Q S EL QK+ +E L D + +T R+L+++
Sbjct: 517 KSQSEYLKISQEKEQQESLALEELELQKKAI---LTESENKLRDLQQEAETYRTRILELE 573
Query: 246 DGVAMLEEDVTDDDN--------LELEMNSESEDGAYLDNPPKGALKKLIH------AAK 291
LE+ + ++ N LE E N +++ + K L+ L H K
Sbjct: 574 SS---LEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEK 630
Query: 292 LNASLKTLEGERNQI----------------YIQLSEVDKTKEELTEHIKNLQTEQASLQ 335
L + + E ++ I + +++ E+ E + QTE SL
Sbjct: 631 LQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLS 690
Query: 336 SENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHAT 395
SE + KL+++L V+ + Q ++MK +E K +K +VD +I
Sbjct: 691 SELSEVLKARHKLEEELSVLKD--QTDKMKQE----LEAKMDEQKNHHQQQVDSIIKEHE 744
Query: 396 EELETYRKRAKD--------LKEFEKTIHFYQKKI 422
++ K KD LKE +K + +Q +
Sbjct: 745 VSIQRTEKALKDQINQLELLLKERDKHLKEHQAHV 779
Score = 60.8 bits (146), Expect = 4e-09
Identities = 87/424 (20%), Positives = 178/424 (41%), Gaps = 92/424 (21%)
Query: 79 ESSLKNASF--------------------------EKEATE---------AQSLEATCEK 103
E + N SF EKEA + A E+ +
Sbjct: 1284 EQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQ 1343
Query: 104 LNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMT 163
L + SE ++ + +++ELKE+K + S ++ + D++ ++Q+ S+ EA ++
Sbjct: 1344 LKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQN------SISLSEKEAAIS 1397
Query: 164 FKRFQANEERLEI--EIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQ--------K 213
R Q +EE+ E+ ++QD + L + + L++ + W + SE K+ +
Sbjct: 1398 SLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQ 1457
Query: 214 RTFEDSKVHAE---QVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDD--------DNLE 262
T ++ ++ E + +K+ I L E L + L+ ++ DD NLE
Sbjct: 1458 NTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLE 1517
Query: 263 LEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQL-----------S 311
E+ S++ L++ +K I LN LK +++ + +L
Sbjct: 1518 TELKSQTARIMELED---HITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGE 1574
Query: 312 EVDKTKEELTEHIKNLQTE----QASLQSENTHFESENQKLQQKLKVMTELYQENEMKLY 367
E D +E E I L+ + +A L+++ E N ++ K + + L E +
Sbjct: 1575 EKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESA 1634
Query: 368 RKLIVEEKCRLEKEEKLSKV-DEMISHATEELETYRKRAKD--------LKEFEKTIHFY 418
KL + + + E+K++ + +++S E+ E Y+K + L+E E+ +H
Sbjct: 1635 AKL---AELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHIL 1691
Query: 419 QKKI 422
++K+
Sbjct: 1692 EEKL 1695
Score = 58.2 bits (139), Expect = 3e-08
Identities = 86/417 (20%), Positives = 192/417 (46%), Gaps = 34/417 (8%)
Query: 63 LEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSELVHEILCLEKEL 122
L++ S ++ Y+ + + ++E++ + Q E ++ V E+ +K++
Sbjct: 793 LQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDV 852
Query: 123 KEEKSKHSEQ-NELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDA 181
E H Q +LM + K+ +E + KSL +QV E+K+ N+E+ + +
Sbjct: 853 CTELDAHKIQVQDLMQQLEKQNSEMEQKVKSL-TQVYESKLE----DGNKEQEQTK---- 903
Query: 182 WKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDK-ENHIKTLTER 240
L E + +LQ E K+++ E++ QK + ++ +H +LN++ E K ++
Sbjct: 904 ----QILVEKENMILQMREGQKKEI-EILTQKLSAKEDSIH---ILNEEYETKFKNQEKK 955
Query: 241 LLKMKDGVAMLEEDVTDD-DNLELEMNSESEDGAY-LDNPPKGALKKLIHAAKLNA---- 294
+ K+K ++E + + E ++ E E+ A L K K++ A+ N+
Sbjct: 956 MEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGIS 1015
Query: 295 -SLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLK 353
++ LE + + L+EV + EL + I ++ ++ + Q+E E +LQ+K +
Sbjct: 1016 DAVSRLETNQKEQIESLTEVH--RRELNDVI-SIWEKKLNQQAEELQ-EIHEIQLQEKEQ 1071
Query: 354 VMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKEFEK 413
+ EL Q+ + K + ++ KEE + K D ++ E+L+ L + E
Sbjct: 1072 EVAELKQKILLFGCEKEEMNKEITWLKEEGV-KQDTTLNELQEQLKQKSAHVNSLAQDET 1130
Query: 414 TIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKD 470
+ + +K+ E + + + L +L+ +++K++E+ K+K +++
Sbjct: 1131 KLKAHLEKL---EVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEE 1184
Score = 56.6 bits (135), Expect = 8e-08
Identities = 91/439 (20%), Positives = 192/439 (43%), Gaps = 78/439 (17%)
Query: 36 VTSRLYVRREKKFAVALSGLIEE-KCKLLEKFSLVQKEYEGYEVESSLKNASFEKEATE- 93
VT+ ++REKK L G++ + + K L + + +++E + +++A +
Sbjct: 161 VTAYQMLQREKK---KLQGILSQSQDKSLRRIAELREELQ------------MDQQAKKH 205
Query: 94 -AQSLEATCEKLNRFNSELVHEILCLEKELKE-----EKSKHSEQNELMADISKRIQSLE 147
+ +A+ E+ +++ S L ++ L++ L+ + K Q E A++ + ++ E
Sbjct: 206 LQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENPE 265
Query: 148 DESKSLKSQVAEAKMTFKRFQANEERLEI------EIQDAWKENSELQESQKQLLQEAEV 201
+ + + K T + Q +R E E + KE L S+K+ LQE
Sbjct: 266 SDGEPVVEDGTSVK-TLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLD 324
Query: 202 WKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTL--------TERLLKMKDGVAMLEE 253
+ Q E IK E +K+ + L D +N I+ L E +M + + M EE
Sbjct: 325 ERLQELEKIKDLHMAEKTKLITQ--LRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEE 382
Query: 254 DVTDDDNLELEMNSESED-GAYLDNPPKGALKKLIHA---------------AKLNASLK 297
++ + +M ++ E+ + + A ++L A A+++ +K
Sbjct: 383 EIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIK 442
Query: 298 TLE--GERNQIYIQLSEVDKTKEELTEHIKNLQTEQASL-------------QSENTHFE 342
T+E E +I +Q E+ + K+E+ + +K EQ + Q +
Sbjct: 443 TIEKTSEEERISLQ-QELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQ 501
Query: 343 SENQKLQQKLKVMTELYQENEMKL-----YRKLIVEEKCRLEKEEKLSKVDEMISHATEE 397
+ ++ Q+++KV E Q +K+ ++ + E+ L+K+ L++ + + +E
Sbjct: 502 TREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQE 561
Query: 398 LETYRKRAKDLK-EFEKTI 415
ETYR R +L+ EK++
Sbjct: 562 AETYRTRILELESSLEKSL 580
Score = 55.1 bits (131), Expect = 2e-07
Identities = 84/371 (22%), Positives = 166/371 (44%), Gaps = 49/371 (13%)
Query: 56 IEEKCKLLEKFSLVQKEY-------EGYEVESSLKNASFEKEATEAQSLEATCE----KL 104
+EEK K K+SL+ ++ + + +L+N F+ Q E TC+ K+
Sbjct: 1801 LEEKNK---KYSLIVAQHVEKEGGKNNIQAKQNLENV-FDDVQKTLQEKELTCQILEQKI 1856
Query: 105 NRFNSELVHEILCLEKELKEEKSKHSEQNEL--MADISKRIQSLED--ESKSLKSQVAEA 160
+S LV + E++E SK+ + L M +K + LE+ E KS KS + +
Sbjct: 1857 KELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKS-KSHLVQP 1915
Query: 161 KMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVW-KEQVSELIKQKRTFEDS 219
K+ +A LE ++ A +E +L + +L ++ + KE EL K+ ++
Sbjct: 1916 KL-LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQE 1974
Query: 220 KVHAEQVLNDKEN----HIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESE-DGAY 274
+ E++ ++E+ H TL + + + +A E+++ + ++ +N E +
Sbjct: 1975 R--EEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQEL--EMTIKETINKAQEVEAEL 2030
Query: 275 LDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASL 334
L++ + + L A+ + LK +I +D +EE+T +++LQT+ L
Sbjct: 2031 LESHQEETNQLLKKIAEKDDDLKRTAKRYEEI------LDAREEEMTAKVRDLQTQLEEL 2084
Query: 335 QSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVD--EMIS 392
Q +K QQKL+ +N + + + +K L + KL + + E I
Sbjct: 2085 Q----------KKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIH 2134
Query: 393 HATEELETYRK 403
+ + L+ Y K
Sbjct: 2135 NLEDRLKKYEK 2145
Score = 53.5 bits (127), Expect = 7e-07
Identities = 89/496 (17%), Positives = 208/496 (41%), Gaps = 81/496 (16%)
Query: 46 KKFAVALSGLIEEKCKL---LEKFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCE 102
K+ + ++ L +++ KL LEK + ++ SLK +F +E + L+ E
Sbjct: 1116 KQKSAHVNSLAQDETKLKAHLEKLEV--------DLNKSLKENTFLQE--QLVELKMLAE 1165
Query: 103 KLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDE------------- 149
+ R SEL ++ ++E + KS H + N+ + D S + L +E
Sbjct: 1166 EDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTE 1225
Query: 150 -----------------SKSLKSQVAEAKMTFKRFQ-------ANEERLEIEIQDAWKEN 185
+ ++ S+++ + + + LE +++ +E
Sbjct: 1226 ALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQ 1285
Query: 186 SELQESQKQLLQEAE-------VWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLT 238
+ L S +Q + E K + L+ +K + + +Q ++KE+ I L
Sbjct: 1286 NTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLK 1345
Query: 239 ERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKT 298
+ L + + V +++E++ + ++E++S S+ L+ + ++ A +++ K
Sbjct: 1346 KELSENINAVTLMKEELKEK---KVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQ 1402
Query: 299 LEGERNQIYIQLSE-------VDKTKEELTEHIKNLQTE----QASLQSENTHFESENQK 347
+ E+ ++ Q+ + + K K E + + + + QS T ++ ++
Sbjct: 1403 YDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKE 1462
Query: 348 LQQKLKVMT-ELYQENE-MKLYRKLIVEEKCRL-----EKEEKLSKVDEMISHATEELET 400
LQ +L++ + E Y+++E + L ++ + ++ R E E+ SK+++ S+ EL++
Sbjct: 1463 LQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKS 1522
Query: 401 YRKRAKDLKEF--EKTIHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLT 458
R +L++ +KTI +L + ++ L ++ ++
Sbjct: 1523 QTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQK-LQHFQELGEEKDNRVK 1581
Query: 459 EIEFKIKLLEKDPYGL 474
E E KI LE Y +
Sbjct: 1582 EAEEKILTLENQVYSM 1597
Score = 53.5 bits (127), Expect = 7e-07
Identities = 93/436 (21%), Positives = 174/436 (39%), Gaps = 85/436 (19%)
Query: 32 SFRSVTSRLYVRREKKFAVALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEA 91
S +S L ++ + + + L E K K +K + ++K+ L + EKE
Sbjct: 1614 SVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQ---------LLSQMEEKEE 1664
Query: 92 TEAQSLEATCEKLNRFNSELVHEILCLEKELKEEKSKHSE-------------------- 131
+ E+ +LN E E+ LE++LK +S SE
Sbjct: 1665 QYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEA 1724
Query: 132 ------QNELMADISKRIQSLEDESKSLKSQVAEAKMTFK-----RFQANEERLEIEIQD 180
Q IS ++L ++ K L+ E + T R Q E +++E +
Sbjct: 1725 DSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAE 1784
Query: 181 AWKE---------NSELQESQKQ--LLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLND 229
A + EL+E K+ L+ V KE I+ K+ E+ ++ L +
Sbjct: 1785 AKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQE 1844
Query: 230 K-------ENHIKTLTERLLKMKDGVAMLEEDVTDD-DNLEL--EMNSESEDGAYLDNPP 279
K E IK L L++ K+ + E++T + L+ +M+ ++ L+
Sbjct: 1845 KELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENT 1904
Query: 280 KGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENT 339
+ K + KL L +E + N + +L+ ++ K++L + I LQ + L+ E+
Sbjct: 1905 EEKSKSHLVQPKL---LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH- 1960
Query: 340 HFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELE 399
QQ+L+++ + Y + EEK + E+E+ K + + E
Sbjct: 1961 ---------QQELEILKKEYDQER---------EEKIKQEQEDLELKHNSTLKQLMREFN 2002
Query: 400 TYRKRAKDLKEFEKTI 415
T + A+ +E E TI
Sbjct: 2003 T--QLAQKEQELEMTI 2016
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 77.4 bits (189), Expect = 4e-14
Identities = 115/518 (22%), Positives = 214/518 (41%), Gaps = 104/518 (20%)
Query: 43 RREKKFAVALSGLIEEKCKLLEKFSLVQKEYEGYEVESS---LKNASFEKEATEAQSLEA 99
++ ++ V+ GL E +L + K+ + E E ++N + +K E +
Sbjct: 749 KKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSK 808
Query: 100 TCEKLNRFNSELVHEILCLEKE---LKEEKSKHSEQNEL----MADISKRIQSLEDESKS 152
E+L + N L E LEK+ L++E + +Q E+ + + + +I +LE E+K+
Sbjct: 809 RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKT 868
Query: 153 LKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQ 212
L ++ K + R + E+ + ++ A + L ++ L+ E ++ ++L K
Sbjct: 869 LSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKL 928
Query: 213 KRTFEDSKVHAEQVLNDK----------ENHIKTLTERLLKMKDGV-----AMLEEDVTD 257
E ++ E++L+D+ E+ +++ ++ L++K+ A LEE
Sbjct: 929 THELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNY 988
Query: 258 DDNLELEMNS-----------ESEDGAYLDNPP----------------KGALK---KLI 287
+ L E+ + + E+ +PP + LK +LI
Sbjct: 989 NQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLI 1048
Query: 288 HAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQK 347
+ NA TL+ E+ + QL +++ L I LQ + SLQ +NT +++N K
Sbjct: 1049 EVERNNA---TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAK 1105
Query: 348 LQ------------------QKLKVMTELYQENE---------MKLYRKLIVE-EKCRLE 379
LQ Q L + L ENE LY LI + EK L
Sbjct: 1106 LQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELL 1165
Query: 380 KEEKLSKVDEMIS-HAT-----EELETYRKRAKD-----------LKEFEKTIHFYQKKI 422
E + S+ + +IS H T + LE + +D L++ EK + Q+K+
Sbjct: 1166 HERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKM 1225
Query: 423 ILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEI 460
+L E K H+ +A + ND K TE+
Sbjct: 1226 LL-ENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEV 1262
Score = 73.9 bits (180), Expect = 5e-13
Identities = 105/455 (23%), Positives = 196/455 (43%), Gaps = 56/455 (12%)
Query: 64 EKFSLVQKEYEGYEVES--------SLKNASFEKEATEAQSLEATCEKLN-RFNSELVH- 113
EK +++E E E+ S KN +F+ E+ E ++ + E L R N E +
Sbjct: 656 EKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKC 715
Query: 114 ------EILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRF 167
++ KEL+ EK + + EL+ K+ + LE + L + + T +
Sbjct: 716 ASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENS 775
Query: 168 QANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVL 227
++LE E+QD EN LQ++ L+E ++ +++ +L K+ ++ E E+
Sbjct: 776 NKKIQQLESELQDLEMENQTLQKN----LEELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Query: 228 NDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESED-GAYLDNPPKGALKKL 286
E K L ++ ++KD LEE+ NLE E + S++ G Y ++ +
Sbjct: 832 KQLEKENKRLRQQ-AEIKD--TTLEENNVKIGNLEKENKTLSKEIGIYKESCVR------ 882
Query: 287 IHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHI--KNLQTEQASLQSENTHFESE 344
LK LE E ++ + + KT L E + + L+T+Q + E E E
Sbjct: 883 ---------LKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELE 933
Query: 345 NQKLQQKLKVMTELYQENEMKLYR-KLIVEEKCRLE-KEEKLSKVDEMISHAT------- 395
L ++ + E ++ KL KL K LE KEEK++ ++ + +T
Sbjct: 934 KIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLR 993
Query: 396 EELETYRKRAKDLKEFEKTIHFYQKKIILH------EKKAHDNWSAAWTAERNLNDLRKE 449
+EL+T +K + LK+ + Q + E+++ + + L ++ +
Sbjct: 994 QELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERN 1053
Query: 450 NAHNRQKLTEIEFKIKLLEKDPYGLDVPNTAFGRQ 484
NA + + ++ ++K LE L A RQ
Sbjct: 1054 NATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1088
Score = 72.0 bits (175), Expect = 2e-12
Identities = 91/442 (20%), Positives = 190/442 (42%), Gaps = 41/442 (9%)
Query: 65 KFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSEL------VHEILCL 118
+ L + + E + S ++A ++ E +L ++++ SE+ +H+I
Sbjct: 285 EIELKRLQQENMNLLSDARSARMYRD--ELDALREKAVRVDKLESEVSRYKERLHDIEFY 342
Query: 119 E---KELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLE 175
+ +ELKE+ E ++ D + ++ D+ L+ + + K + +
Sbjct: 343 KARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDR 402
Query: 176 IEIQDAWKENSELQESQKQLLQEAEV--WK-EQVSELIKQKRTFEDSKVHAEQVLNDK-- 230
+I++ +EN L+ +QKQ + E+ W+ EQ+S + + S H L
Sbjct: 403 KKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRL 462
Query: 231 ---ENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLI 287
E ++LT+ + +++ V +E + + +E E S+ L+N
Sbjct: 463 LKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILEN---------- 512
Query: 288 HAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQK 347
+ SL+ + + + ++++KT E L E N + + L+ EN H
Sbjct: 513 EIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE---NSERQIKILEQENEHLNQTVSS 569
Query: 348 LQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKD 407
L+Q+ ++ E ++ K I+ E + E KLSK++ +ELE Y+++ +
Sbjct: 570 LRQRSQISAEARVKDIEK--ENKILHESIK-ETSSKLSKIEFEKRQIKKELEHYKEKGER 626
Query: 408 LKEFEKTIHFYQKKIILHEKKAHD---NWSAAWTAERNLNDLRKENAHNRQKL---TEIE 461
+E E +H +K+ L +KK + E+ ++L +EN ++ L +
Sbjct: 627 AEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLT 686
Query: 462 FKIKLLEKDPYGLDVPNTAFGR 483
F+++ LEK+ LD N R
Sbjct: 687 FQLESLEKENSQLDEENLELRR 708
Score = 62.0 bits (149), Expect = 2e-09
Identities = 95/443 (21%), Positives = 200/443 (45%), Gaps = 86/443 (19%)
Query: 117 CLEKELKEEKSKHSEQNELMADISKRI----QSLEDESKSL---KSQVAEAKMTFKRFQ- 168
C +K +S+ EL AD +I Q LE++++ L K ++ + ++ KR Q
Sbjct: 235 CGSPGMKRTESRQHLSVEL-ADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQ 293
Query: 169 --------ANEERLEIEIQDAWKENS---ELQESQ----KQLLQEAEVWKEQVSELIKQK 213
A R+ + DA +E + + ES+ K+ L + E +K +V EL +
Sbjct: 294 ENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDN 353
Query: 214 RTFEDSKVHAEQVLND---KENHIKTLTERLLKMKDGV-----------AMLEEDVTDDD 259
+ ++K E L + + + L + L++K + +EE + ++
Sbjct: 354 QVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENM 413
Query: 260 NLELEMNSESEDGAYLDNPPKGALKKLIHAAKLN-ASLKTLEGERNQI-YIQLSEVDKTK 317
LE+ ++ +L L+++ ++L+ A K+L E N++ +L +++
Sbjct: 414 TLEMAQKQSMDESLHLG----WELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMEN 469
Query: 318 EELTEHIKNLQTEQASLQ---SENTHFESENQKLQQKLKVM-TELYQENE----MKLYRK 369
+ LT+ ++ L+T S++ S+ E ENQ+L +K++++ E+ QE + + K
Sbjct: 470 QSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSK 529
Query: 370 LIVEEKCRLEK---------EEKLSKVDEMISHATEELETYRKRA--------KDLKEFE 412
+++EK +LEK E ++ +++ H + + + R+R+ KD+++
Sbjct: 530 DLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKEN 589
Query: 413 KTIH--------------FYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLT 458
K +H F +++I + + A E L+ L KEN ++K+T
Sbjct: 590 KILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKIT 649
Query: 459 EIEF---KIKLLEKDPYGLDVPN 478
++ KI+ LE++ L+ N
Sbjct: 650 NLKITCEKIEALEQENSELEREN 672
Score = 59.3 bits (142), Expect = 1e-08
Identities = 94/399 (23%), Positives = 175/399 (43%), Gaps = 59/399 (14%)
Query: 44 REKKFAVALSGLIEEKC----KLLEKFSLVQKEYEGYE--------VESSLKNASFEKEA 91
+E+K A AL +EE +L ++ V+K YE + V+SS S E
Sbjct: 971 KEEKIA-ALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS-PPISGEDNK 1028
Query: 92 TEAQSLEATCEKLN---------RFNSELVHEILCLEKELKEEKSKHSEQNELMADISKR 142
E +S E T E L R N+ L E L+ +LK+ +++++ + + ++
Sbjct: 1029 WERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1088
Query: 143 IQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWK--ENSELQESQKQLLQEAE 200
SL++++ +L++Q AK+ + N + + Q+A + S L+ + +++E E
Sbjct: 1089 TVSLQEQNTTLQTQ--NAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKERE 1146
Query: 201 VWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLE---EDVTD 257
K LIK E +H Q + ++L + +K LE D+ D
Sbjct: 1147 DLKSLYDSLIKDHEKLE--LLHERQA-----SEYESLISKHGTLKSAHKNLEVEHRDLED 1199
Query: 258 DDNLELEMNSESEDGAYLDNPPKGALKKLIHAAK----LNASLKTLEGERNQIYIQLSEV 313
N L+ + ED L+ K +K++ K + A K L GE +++ S++
Sbjct: 1200 RYNQLLKQKGQLED---LEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQL 1256
Query: 314 DKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVM--TELYQENEMKLYRKLI 371
K E L KNL++ + + E T E+E KL+++ + + T N+ +L +L
Sbjct: 1257 LKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQL- 1315
Query: 372 VEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKE 410
K LE+E + H ++++T + + L E
Sbjct: 1316 ---KGNLEEENR---------HLLDQIQTLMLQNRTLLE 1342
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 77.0 bits (188), Expect = 6e-14
Identities = 115/519 (22%), Positives = 214/519 (41%), Gaps = 105/519 (20%)
Query: 43 RREKKFAVALSGLIEEKCKLLEKFSLVQKEYEGYEVESS---LKNASFEKEATEAQSLEA 99
++ ++ V+ GL E +L + K+ + E E ++N + +K E +
Sbjct: 749 KKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSK 808
Query: 100 TCEKLNRFNSELVHEILCLEKE---LKEEKSKHSEQNEL----MADISKRIQSLEDESKS 152
E+L + N L E LEK+ L++E + +Q E+ + + + +I +LE E+K+
Sbjct: 809 RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKT 868
Query: 153 LKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQ 212
L ++ K + R + E+ + ++ A + L ++ L+ E ++ ++L K
Sbjct: 869 LSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKL 928
Query: 213 KRTFEDSKVHAEQVLNDK-----------ENHIKTLTERLLKMKDGV-----AMLEEDVT 256
E ++ E++L+D+ E+ +++ ++ L++K+ A LEE
Sbjct: 929 THELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTN 988
Query: 257 DDDNLELEMNS-----------ESEDGAYLDNPP----------------KGALK---KL 286
+ L E+ + + E+ +PP + LK +L
Sbjct: 989 YNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRL 1048
Query: 287 IHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQ 346
I + NA TL+ E+ + QL +++ L I LQ + SLQ +NT +++N
Sbjct: 1049 IEVERNNA---TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNA 1105
Query: 347 KLQ------------------QKLKVMTELYQENE---------MKLYRKLIVE-EKCRL 378
KLQ Q L + L ENE LY LI + EK L
Sbjct: 1106 KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLEL 1165
Query: 379 EKEEKLSKVDEMIS-HAT-----EELETYRKRAKD-----------LKEFEKTIHFYQKK 421
E + S+ + +IS H T + LE + +D L++ EK + Q+K
Sbjct: 1166 LHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEK 1225
Query: 422 IILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEI 460
++L E K H+ +A + ND K TE+
Sbjct: 1226 MLL-ENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEV 1263
Score = 72.0 bits (175), Expect = 2e-12
Identities = 91/442 (20%), Positives = 190/442 (42%), Gaps = 41/442 (9%)
Query: 65 KFSLVQKEYEGYEVESSLKNASFEKEATEAQSLEATCEKLNRFNSEL------VHEILCL 118
+ L + + E + S ++A ++ E +L ++++ SE+ +H+I
Sbjct: 285 EIELKRLQQENMNLLSDARSARMYRD--ELDALREKAVRVDKLESEVSRYKERLHDIEFY 342
Query: 119 E---KELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLE 175
+ +ELKE+ E ++ D + ++ D+ L+ + + K + +
Sbjct: 343 KARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDR 402
Query: 176 IEIQDAWKENSELQESQKQLLQEAEV--WK-EQVSELIKQKRTFEDSKVHAEQVLNDK-- 230
+I++ +EN L+ +QKQ + E+ W+ EQ+S + + S H L
Sbjct: 403 KKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRL 462
Query: 231 ---ENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLI 287
E ++LT+ + +++ V +E + + +E E S+ L+N
Sbjct: 463 LKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILEN---------- 512
Query: 288 HAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQK 347
+ SL+ + + + ++++KT E L E N + + L+ EN H
Sbjct: 513 EIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE---NSERQIKILEQENEHLNQTVSS 569
Query: 348 LQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKD 407
L+Q+ ++ E ++ K I+ E + E KLSK++ +ELE Y+++ +
Sbjct: 570 LRQRSQISAEARVKDIEK--ENKILHESIK-ETSSKLSKIEFEKRQIKKELEHYKEKGER 626
Query: 408 LKEFEKTIHFYQKKIILHEKKAHD---NWSAAWTAERNLNDLRKENAHNRQKL---TEIE 461
+E E +H +K+ L +KK + E+ ++L +EN ++ L +
Sbjct: 627 AEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLT 686
Query: 462 FKIKLLEKDPYGLDVPNTAFGR 483
F+++ LEK+ LD N R
Sbjct: 687 FQLESLEKENSQLDEENLELRR 708
Score = 70.9 bits (172), Expect = 4e-12
Identities = 97/451 (21%), Positives = 195/451 (43%), Gaps = 47/451 (10%)
Query: 64 EKFSLVQKEYEGYEVES--------SLKNASFEKEATEAQSLEATCEKLN-RFNSELVH- 113
EK +++E E E+ S KN +F+ E+ E ++ + E L R N E +
Sbjct: 656 EKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKC 715
Query: 114 ------EILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRF 167
++ KEL+ EK + + EL+ K+ + LE + L + + T +
Sbjct: 716 ASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENS 775
Query: 168 QANEERLEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVL 227
++LE E+QD EN LQ++ L+E ++ +++ +L K+ ++ E E+
Sbjct: 776 NKKIQQLESELQDLEMENQTLQKN----LEELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Query: 228 NDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESED-GAYLDN-----PPKG 281
E K L ++ ++KD LEE+ NLE E + S++ G Y ++ +
Sbjct: 832 KQLEKENKRLRQQ-AEIKD--TTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEK 888
Query: 282 ALKKLIHAAKLN-ASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNL-QTEQASLQSENT 339
K+L+ A ++ +L TL + ++ +++ E+LT ++ + ++ L E +
Sbjct: 889 ENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQS 948
Query: 340 HFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELE 399
+S + L+ KL E L + L ++E+ E +L + +EL+
Sbjct: 949 TDDSRYKLLESKL----------ESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELK 998
Query: 400 TYRKRAKDLKEFEKTIHFYQKKIILH------EKKAHDNWSAAWTAERNLNDLRKENAHN 453
T +K + LK+ + Q + E+++ + + L ++ + NA
Sbjct: 999 TVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATL 1058
Query: 454 RQKLTEIEFKIKLLEKDPYGLDVPNTAFGRQ 484
+ + ++ ++K LE L A RQ
Sbjct: 1059 QAEKQALKTQLKQLETQNNNLQAQILALQRQ 1089
Score = 62.0 bits (149), Expect = 2e-09
Identities = 95/443 (21%), Positives = 200/443 (45%), Gaps = 86/443 (19%)
Query: 117 CLEKELKEEKSKHSEQNELMADISKRI----QSLEDESKSL---KSQVAEAKMTFKRFQ- 168
C +K +S+ EL AD +I Q LE++++ L K ++ + ++ KR Q
Sbjct: 235 CGSPGMKRTESRQHLSVEL-ADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQ 293
Query: 169 --------ANEERLEIEIQDAWKENS---ELQESQ----KQLLQEAEVWKEQVSELIKQK 213
A R+ + DA +E + + ES+ K+ L + E +K +V EL +
Sbjct: 294 ENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDN 353
Query: 214 RTFEDSKVHAEQVLND---KENHIKTLTERLLKMKDGV-----------AMLEEDVTDDD 259
+ ++K E L + + + L + L++K + +EE + ++
Sbjct: 354 QVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENM 413
Query: 260 NLELEMNSESEDGAYLDNPPKGALKKLIHAAKLN-ASLKTLEGERNQI-YIQLSEVDKTK 317
LE+ ++ +L L+++ ++L+ A K+L E N++ +L +++
Sbjct: 414 TLEMAQKQSMDESLHLG----WELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMEN 469
Query: 318 EELTEHIKNLQTEQASLQ---SENTHFESENQKLQQKLKVM-TELYQENE----MKLYRK 369
+ LT+ ++ L+T S++ S+ E ENQ+L +K++++ E+ QE + + K
Sbjct: 470 QSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSK 529
Query: 370 LIVEEKCRLEK---------EEKLSKVDEMISHATEELETYRKRA--------KDLKEFE 412
+++EK +LEK E ++ +++ H + + + R+R+ KD+++
Sbjct: 530 DLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKEN 589
Query: 413 KTIH--------------FYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLT 458
K +H F +++I + + A E L+ L KEN ++K+T
Sbjct: 590 KILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKIT 649
Query: 459 EIEF---KIKLLEKDPYGLDVPN 478
++ KI+ LE++ L+ N
Sbjct: 650 NLKITCEKIEALEQENSELEREN 672
Score = 59.3 bits (142), Expect = 1e-08
Identities = 94/399 (23%), Positives = 175/399 (43%), Gaps = 59/399 (14%)
Query: 44 REKKFAVALSGLIEEKC----KLLEKFSLVQKEYEGYE--------VESSLKNASFEKEA 91
+E+K A AL +EE +L ++ V+K YE + V+SS S E
Sbjct: 972 KEEKIA-ALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS-PPISGEDNK 1029
Query: 92 TEAQSLEATCEKLN---------RFNSELVHEILCLEKELKEEKSKHSEQNELMADISKR 142
E +S E T E L R N+ L E L+ +LK+ +++++ + + ++
Sbjct: 1030 WERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1089
Query: 143 IQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWK--ENSELQESQKQLLQEAE 200
SL++++ +L++Q AK+ + N + + Q+A + S L+ + +++E E
Sbjct: 1090 TVSLQEQNTTLQTQ--NAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKERE 1147
Query: 201 VWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLE---EDVTD 257
K LIK E +H Q + ++L + +K LE D+ D
Sbjct: 1148 DLKSLYDSLIKDHEKLE--LLHERQA-----SEYESLISKHGTLKSAHKNLEVEHRDLED 1200
Query: 258 DDNLELEMNSESEDGAYLDNPPKGALKKLIHAAK----LNASLKTLEGERNQIYIQLSEV 313
N L+ + ED L+ K +K++ K + A K L GE +++ S++
Sbjct: 1201 RYNQLLKQKGQLED---LEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQL 1257
Query: 314 DKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVM--TELYQENEMKLYRKLI 371
K E L KNL++ + + E T E+E KL+++ + + T N+ +L +L
Sbjct: 1258 LKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQL- 1316
Query: 372 VEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKE 410
K LE+E + H ++++T + + L E
Sbjct: 1317 ---KGNLEEENR---------HLLDQIQTLMLQNRTLLE 1343
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,188,475
Number of Sequences: 37866
Number of extensions: 2082507
Number of successful extensions: 19934
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 415
Number of HSP's successfully gapped in prelim test: 1412
Number of HSP's that attempted gapping in prelim test: 10315
Number of HSP's gapped (non-prelim): 6626
length of query: 745
length of database: 18,247,518
effective HSP length: 110
effective length of query: 635
effective length of database: 14,082,258
effective search space: 8942233830
effective search space used: 8942233830
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.