Guide to the Human Genome
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Search of human proteins with 90193624

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|90193624 integrator complex subunit 6 isoform c [Homo
sapiens]
         (115 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|90193624 integrator complex subunit 6 isoform c [Homo sapiens]     232   5e-62
gi|11024694 integrator complex subunit 6 isoform a [Homo sapiens]     228   8e-61
gi|90193622 integrator complex subunit 6 isoform b [Homo sapiens]     204   9e-54
gi|94536743 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B [Ho...   202   4e-53
gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo s...    31   0.24 
gi|50363228 RAB11 family interacting protein 1 isoform 1 [Homo s...    31   0.24 
gi|38261962 activating transcription factor 7 interacting protei...    28   1.6  
gi|139394579 zinc finger and BTB domain containing 40 [Homo sapi...    27   2.7  
gi|139394556 zinc finger and BTB domain containing 40 [Homo sapi...    27   2.7  
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  27   3.5  
gi|9845285 cytochrome P450, family 26, subfamily b, polypeptide ...    27   3.5  
gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s...    26   5.9  
gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo s...    26   5.9  
gi|14249342 internexin neuronal intermediate filament protein, a...    26   7.7  
gi|62952502 cytochrome P450, family 26, subfamily C, polypeptide...    26   7.7  

>gi|90193624 integrator complex subunit 6 isoform c [Homo sapiens]
          Length = 115

 Score =  232 bits (591), Expect = 5e-62
 Identities = 115/115 (100%), Positives = 115/115 (100%)

Query: 1   MPILLFLIDTSASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPY 60
           MPILLFLIDTSASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPY
Sbjct: 1   MPILLFLIDTSASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPY 60

Query: 61  AIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQVG 115
           AIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQVG
Sbjct: 61  AIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQVG 115


>gi|11024694 integrator complex subunit 6 isoform a [Homo sapiens]
          Length = 887

 Score =  228 bits (581), Expect = 8e-61
 Identities = 113/113 (100%), Positives = 113/113 (100%)

Query: 1   MPILLFLIDTSASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPY 60
           MPILLFLIDTSASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPY
Sbjct: 1   MPILLFLIDTSASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPY 60

Query: 61  AIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQ 113
           AIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQ
Sbjct: 61  AIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQ 113


>gi|90193622 integrator complex subunit 6 isoform b [Homo sapiens]
          Length = 874

 Score =  204 bits (520), Expect = 9e-54
 Identities = 100/100 (100%), Positives = 100/100 (100%)

Query: 14  MNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATF 73
           MNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATF
Sbjct: 1   MNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATF 60

Query: 74  MNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQ 113
           MNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQ
Sbjct: 61  MNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQ 100


>gi|94536743 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B [Homo
           sapiens]
          Length = 861

 Score =  202 bits (515), Expect = 4e-53
 Identities = 97/113 (85%), Positives = 108/113 (95%)

Query: 1   MPILLFLIDTSASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPY 60
           MPILLFLIDTSASMNQR+ LGT+YLD AKGAVE F+KLRARDPASRGDRYMLVT++EPPY
Sbjct: 1   MPILLFLIDTSASMNQRTDLGTSYLDIAKGAVELFLKLRARDPASRGDRYMLVTYDEPPY 60

Query: 61  AIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQ 113
            IKAGWKENHATFM+ELKNLQA GLTTLGQ+LR++FDLLNLNRL++GIDNYGQ
Sbjct: 61  CIKAGWKENHATFMSELKNLQASGLTTLGQALRSSFDLLNLNRLISGIDNYGQ 113


>gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo
           sapiens]
          Length = 1283

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 17/74 (22%), Positives = 29/74 (39%)

Query: 38  LRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFD 97
           LRA+ P    D Y ++   +  YA     +   A    E    +   L + G +      
Sbjct: 30  LRAKGPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATFELPSLLSSGPAAAATLQ 89

Query: 98  LLNLNRLVTGIDNY 111
           L  L+R + G+D +
Sbjct: 90  LTVLHRALLGLDKF 103


>gi|50363228 RAB11 family interacting protein 1 isoform 1 [Homo
           sapiens]
          Length = 649

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 17/74 (22%), Positives = 29/74 (39%)

Query: 38  LRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFD 97
           LRA+ P    D Y ++   +  YA     +   A    E    +   L + G +      
Sbjct: 30  LRAKGPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATFELPSLLSSGPAAAATLQ 89

Query: 98  LLNLNRLVTGIDNY 111
           L  L+R + G+D +
Sbjct: 90  LTVLHRALLGLDKF 103


>gi|38261962 activating transcription factor 7 interacting protein
            [Homo sapiens]
          Length = 1270

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 11   SASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTF-EEPPYAIKAGWKEN 69
            S S+ Q+ HL    + +  G V ++  L      +  D Y L  + EEP   + + WK+ 
Sbjct: 1157 STSLPQKPHLKLARVQSQNGIVLSWSVLEVDRSCATVDSYHLYAYHEEPSATVPSQWKK- 1215

Query: 70   HATFMNELKNLQAEGLTTLGQ 90
                + E+K L      TL Q
Sbjct: 1216 ----IGEVKALPLPMACTLTQ 1232


>gi|139394579 zinc finger and BTB domain containing 40 [Homo
           sapiens]
          Length = 1239

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 16/34 (47%), Positives = 19/34 (55%)

Query: 68  ENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNL 101
           EN    M E K L AEGL  L Q+++T F  L L
Sbjct: 405 ENLLHRMTEEKTLTAEGLVKLLQAVKTTFPNLGL 438


>gi|139394556 zinc finger and BTB domain containing 40 [Homo
           sapiens]
          Length = 1239

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 16/34 (47%), Positives = 19/34 (55%)

Query: 68  ENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNL 101
           EN    M E K L AEGL  L Q+++T F  L L
Sbjct: 405 ENLLHRMTEEKTLTAEGLVKLLQAVKTTFPNLGL 438


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 13/31 (41%), Positives = 18/31 (58%)

Query: 58  PPYAIKAGWKENHATFMNELKNLQAEGLTTL 88
           PP +  AG  +NH   MN LK+  A+  +TL
Sbjct: 630 PPVSSMAGNTKNHPMLMNLLKDNPAQDFSTL 660


>gi|9845285 cytochrome P450, family 26, subfamily b, polypeptide 1
           [Homo sapiens]
          Length = 512

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 4/50 (8%)

Query: 21  GTTYLDTAKGA--VETFMK--LRARDPASRGDRYMLVTFEEPPYAIKAGW 66
           GT  LDT  G   ++  +K  +R   P S G R +L TFE   + I  GW
Sbjct: 341 GTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELDGFQIPKGW 390


>gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
           sapiens]
          Length = 1223

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 13/69 (18%)

Query: 21  GTTYLDTAKGAVETFMKLRARDPASR--GDRYMLVTFE-----EPP------YAIKAGWK 67
           G  Y++TA+   ET MK+R   P +   GD   L  F+     EPP      ++    WK
Sbjct: 192 GLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWK 251

Query: 68  ENHATFMNE 76
           EN     N+
Sbjct: 252 ENKFPLSNQ 260


>gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo
           sapiens]
          Length = 387

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 13/69 (18%)

Query: 21  GTTYLDTAKGAVETFMKLRARDPASR--GDRYMLVTFE-----EPP------YAIKAGWK 67
           G  Y++TA+   ET MK+R   P +   GD   L  F+     EPP      ++    WK
Sbjct: 159 GLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWK 218

Query: 68  ENHATFMNE 76
           EN     N+
Sbjct: 219 ENKFPLSNQ 227


>gi|14249342 internexin neuronal intermediate filament protein,
           alpha [Homo sapiens]
          Length = 499

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 23/98 (23%), Positives = 48/98 (48%), Gaps = 12/98 (12%)

Query: 12  ASMNQRSHLGTTYLDTAKGAVETFMK-LRARDPASRGDR-------YMLVTFEEPPYAIK 63
           A++N+++   T  +  ++  +  + + L+AR     G R         ++  EE   A  
Sbjct: 292 ANLNEQAARSTEAIRASREEIHEYRRQLQARTIEIEGLRGANESLERQILELEERHSAEV 351

Query: 64  AGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNL 101
           AG++++     N+L+N ++E    + + LR   DLLN+
Sbjct: 352 AGYQDSIGQLENDLRNTKSE----MARHLREYQDLLNV 385


>gi|62952502 cytochrome P450, family 26, subfamily C, polypeptide 1
           [Homo sapiens]
          Length = 522

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 14/29 (48%), Positives = 14/29 (48%)

Query: 38  LRARDPASRGDRYMLVTFEEPPYAIKAGW 66
           LR   P S G R  L TFE   Y I  GW
Sbjct: 377 LRLLPPVSGGYRTALRTFELDGYQIPKGW 405


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,638,628
Number of Sequences: 37866
Number of extensions: 123840
Number of successful extensions: 254
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 243
Number of HSP's gapped (non-prelim): 16
length of query: 115
length of database: 18,247,518
effective HSP length: 85
effective length of query: 30
effective length of database: 15,028,908
effective search space: 450867240
effective search space used: 450867240
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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