Guide to the Human Genome
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Search of human proteins with 89993692

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|89993692 mouse double minute 2 homolog isoform MDM2b [Homo
sapiens]
         (111 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|89993692 mouse double minute 2 homolog isoform MDM2b [Homo sa...   223   2e-59
gi|223890205 mouse double minute 2 homolog isoform MDM2h [Homo s...   178   9e-46
gi|89993691 mouse double minute 2 homolog isoform MDM2e [Homo sa...   178   9e-46
gi|89993693 mouse double minute 2 homolog isoform MDM2d [Homo sa...   178   9e-46
gi|89993690 mouse double minute 2 homolog isoform MDM2a [Homo sa...   178   9e-46
gi|89993689 mouse double minute 2 homolog isoform MDM2 [Homo sap...   178   9e-46
gi|223890201 mouse double minute 2 homolog isoform MDM2g [Homo s...   167   2e-42
gi|223890197 mouse double minute 2 homolog isoform MDM2f [Homo s...   117   2e-27
gi|223890207 mouse double minute 2 homolog isoform MDM2i [Homo s...   105   6e-24
gi|88702791 mouse double minute 4 homolog [Homo sapiens]               73   4e-14
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap...    31   0.24 
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap...    31   0.24 
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [...    28   2.1  
gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [...    28   2.1  
gi|27436910 partner and localizer of BRCA2 [Homo sapiens]              27   2.7  
gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens]                27   4.6  
gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens]                27   4.6  
gi|160420295 hypothetical protein LOC85459 [Homo sapiens]              27   4.6  
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]             26   6.0  
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]             26   6.0  

>gi|89993692 mouse double minute 2 homolog isoform MDM2b [Homo
           sapiens]
          Length = 111

 Score =  223 bits (569), Expect = 2e-59
 Identities = 111/111 (100%), Positives = 111/111 (100%)

Query: 1   MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
           MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1   MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60

Query: 61  FYLGQYIMTKRLYDEKQQHIVYCSNDCANLFPLVDLSIRELYISNYITLGI 111
           FYLGQYIMTKRLYDEKQQHIVYCSNDCANLFPLVDLSIRELYISNYITLGI
Sbjct: 61  FYLGQYIMTKRLYDEKQQHIVYCSNDCANLFPLVDLSIRELYISNYITLGI 111


>gi|223890205 mouse double minute 2 homolog isoform MDM2h [Homo
           sapiens]
          Length = 442

 Score =  178 bits (451), Expect = 9e-46
 Identities = 90/101 (89%), Positives = 94/101 (93%), Gaps = 1/101 (0%)

Query: 1   MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
           MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1   MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60

Query: 61  FYLGQYIMTKRLYDEKQQHIVYCSND-CANLFPLVDLSIRE 100
           FYLGQYIMTKRLYDEKQQHIVYCSND   +LF +   S++E
Sbjct: 61  FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKE 101


>gi|89993691 mouse double minute 2 homolog isoform MDM2e [Homo
           sapiens]
          Length = 179

 Score =  178 bits (451), Expect = 9e-46
 Identities = 90/101 (89%), Positives = 94/101 (93%), Gaps = 1/101 (0%)

Query: 1   MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
           MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1   MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60

Query: 61  FYLGQYIMTKRLYDEKQQHIVYCSND-CANLFPLVDLSIRE 100
           FYLGQYIMTKRLYDEKQQHIVYCSND   +LF +   S++E
Sbjct: 61  FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKE 101


>gi|89993693 mouse double minute 2 homolog isoform MDM2d [Homo
           sapiens]
          Length = 172

 Score =  178 bits (451), Expect = 9e-46
 Identities = 90/101 (89%), Positives = 94/101 (93%), Gaps = 1/101 (0%)

Query: 1   MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
           MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1   MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60

Query: 61  FYLGQYIMTKRLYDEKQQHIVYCSND-CANLFPLVDLSIRE 100
           FYLGQYIMTKRLYDEKQQHIVYCSND   +LF +   S++E
Sbjct: 61  FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKE 101


>gi|89993690 mouse double minute 2 homolog isoform MDM2a [Homo
           sapiens]
          Length = 249

 Score =  178 bits (451), Expect = 9e-46
 Identities = 90/101 (89%), Positives = 94/101 (93%), Gaps = 1/101 (0%)

Query: 1   MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
           MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1   MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60

Query: 61  FYLGQYIMTKRLYDEKQQHIVYCSND-CANLFPLVDLSIRE 100
           FYLGQYIMTKRLYDEKQQHIVYCSND   +LF +   S++E
Sbjct: 61  FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKE 101


>gi|89993689 mouse double minute 2 homolog isoform MDM2 [Homo
           sapiens]
          Length = 497

 Score =  178 bits (451), Expect = 9e-46
 Identities = 90/101 (89%), Positives = 94/101 (93%), Gaps = 1/101 (0%)

Query: 1   MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
           MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1   MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60

Query: 61  FYLGQYIMTKRLYDEKQQHIVYCSND-CANLFPLVDLSIRE 100
           FYLGQYIMTKRLYDEKQQHIVYCSND   +LF +   S++E
Sbjct: 61  FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKE 101


>gi|223890201 mouse double minute 2 homolog isoform MDM2g [Homo
           sapiens]
          Length = 444

 Score =  167 bits (423), Expect = 2e-42
 Identities = 84/95 (88%), Positives = 88/95 (92%), Gaps = 1/95 (1%)

Query: 7   MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 66
           MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY
Sbjct: 1   MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 60

Query: 67  IMTKRLYDEKQQHIVYCSND-CANLFPLVDLSIRE 100
           IMTKRLYDEKQQHIVYCSND   +LF +   S++E
Sbjct: 61  IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKE 95


>gi|223890197 mouse double minute 2 homolog isoform MDM2f [Homo
          sapiens]
          Length = 452

 Score =  117 bits (293), Expect = 2e-27
 Identities = 58/61 (95%), Positives = 60/61 (98%)

Query: 1  MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
          MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE +
Sbjct: 1  MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEKI 60

Query: 61 F 61
          +
Sbjct: 61 Y 61


>gi|223890207 mouse double minute 2 homolog isoform MDM2i [Homo
          sapiens]
          Length = 295

 Score =  105 bits (263), Expect = 6e-24
 Identities = 53/54 (98%), Positives = 53/54 (98%)

Query: 7  MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
          MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE L
Sbjct: 1  MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEDL 54


>gi|88702791 mouse double minute 4 homolog [Homo sapiens]
          Length = 490

 Score = 73.2 bits (178), Expect = 4e-14
 Identities = 32/53 (60%), Positives = 43/53 (81%)

Query: 34 VRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSND 86
          VRPK  LLK+L + GAQ + +T+KEV+ YLGQYIM K+LYD+++QH+VYC  D
Sbjct: 27 VRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGD 79


>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
           sapiens]
          Length = 839

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 10/67 (14%)

Query: 25  IPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCS 84
           IP S QE  + P PL L+ ++S  AQ           Y   Y ++ R  D++  ++ Y  
Sbjct: 140 IPCSMQENSLGPFPLFLQQVESDAAQN----------YTVFYSISGRGVDKEPLNLFYIE 189

Query: 85  NDCANLF 91
            D  NLF
Sbjct: 190 RDTGNLF 196


>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
           sapiens]
          Length = 896

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 10/67 (14%)

Query: 25  IPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCS 84
           IP S QE  + P PL L+ ++S  AQ           Y   Y ++ R  D++  ++ Y  
Sbjct: 140 IPCSMQENSLGPFPLFLQQVESDAAQN----------YTVFYSISGRGVDKEPLNLFYIE 189

Query: 85  NDCANLF 91
            D  NLF
Sbjct: 190 RDTGNLF 196


>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a
           [Homo sapiens]
          Length = 1336

 Score = 27.7 bits (60), Expect = 2.1
 Identities = 14/44 (31%), Positives = 25/44 (56%), Gaps = 1/44 (2%)

Query: 15  PTDGAVTTSQIPASEQETL-VRPKPLLLKLLKSVGAQKDTYTMK 57
           PTDG+ + +  P+ +QE L  +PK   L+ LK   + +   ++K
Sbjct: 439 PTDGSTSPTSTPSEDQEALGKKPKAPALRFLKRTLSNESEESVK 482


>gi|54112380 F-box and leucine-rich repeat protein 10 isoform b
           [Homo sapiens]
          Length = 1265

 Score = 27.7 bits (60), Expect = 2.1
 Identities = 14/44 (31%), Positives = 25/44 (56%), Gaps = 1/44 (2%)

Query: 15  PTDGAVTTSQIPASEQETL-VRPKPLLLKLLKSVGAQKDTYTMK 57
           PTDG+ + +  P+ +QE L  +PK   L+ LK   + +   ++K
Sbjct: 408 PTDGSTSPTSTPSEDQEALGKKPKAPALRFLKRTLSNESEESVK 451


>gi|27436910 partner and localizer of BRCA2 [Homo sapiens]
          Length = 1186

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 1/53 (1%)

Query: 29  EQETLVRPKPLLLKLLKSVGAQKDTYTMKE-VLFYLGQYIMTKRLYDEKQQHI 80
           E E L +PK L L+    + A+K + T+ E +LF    Y+ T R     Q+ +
Sbjct: 371 ESEILSQPKSLSLEATSPLSAEKHSCTVPEGLLFPAEYYVRTTRSMSNCQRKV 423


>gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens]
          Length = 562

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 18/61 (29%), Positives = 28/61 (45%)

Query: 16  TDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDE 75
           TD + T   I   E     RP+P ++ ++   G+ K T ++K    Y  QYI    L  +
Sbjct: 110 TDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRK 169

Query: 76  K 76
           K
Sbjct: 170 K 170


>gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens]
          Length = 536

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 18/61 (29%), Positives = 28/61 (45%)

Query: 16  TDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDE 75
           TD + T   I   E     RP+P ++ ++   G+ K T ++K    Y  QYI    L  +
Sbjct: 84  TDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRK 143

Query: 76  K 76
           K
Sbjct: 144 K 144


>gi|160420295 hypothetical protein LOC85459 [Homo sapiens]
          Length = 2601

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 11/58 (18%)

Query: 2   VRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEV 59
           V   ++C++   VP    + T QIP+         K L  KLL  + +QK  +T+K +
Sbjct: 360 VTEAEICSSETDVPL--VMKTQQIPS---------KVLFKKLLNKIRSQKSLWTIKSM 406


>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
          Length = 888

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 13/32 (40%), Positives = 18/32 (56%)

Query: 9   NTNMSVPTDGAVTTSQIPASEQETLVRPKPLL 40
           NT+ SVPT    T  Q+   ++  L R +PLL
Sbjct: 161 NTSPSVPTTTTATEEQVSEPKKWNLRRNRPLL 192


>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
          Length = 948

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 13/32 (40%), Positives = 18/32 (56%)

Query: 9   NTNMSVPTDGAVTTSQIPASEQETLVRPKPLL 40
           NT+ SVPT    T  Q+   ++  L R +PLL
Sbjct: 161 NTSPSVPTTTTATEEQVSEPKKWNLRRNRPLL 192


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.134    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,771,214
Number of Sequences: 37866
Number of extensions: 137877
Number of successful extensions: 339
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 324
Number of HSP's gapped (non-prelim): 20
length of query: 111
length of database: 18,247,518
effective HSP length: 81
effective length of query: 30
effective length of database: 15,180,372
effective search space: 455411160
effective search space used: 455411160
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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