Guide to the Human Genome
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Search of human proteins with 14149771

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14149771 WD repeat domain 54 [Homo sapiens]
         (334 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14149771 WD repeat domain 54 [Homo sapiens]                        688   0.0  
gi|215272341 WD repeat domain 58 isoform 2 [Homo sapiens]              45   7e-05
gi|31543164 WD repeat domain 58 isoform 1 [Homo sapiens]               45   7e-05
gi|56243583 WD repeat domain 18 [Homo sapiens]                         40   0.004
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho...    39   0.005
gi|118402582 cell division cycle 20 [Homo sapiens]                     39   0.007
gi|5803221 WD repeat-containing protein 3 [Homo sapiens]               39   0.008
gi|53759148 retinoblastoma binding protein 5 [Homo sapiens]            38   0.014
gi|18874090 WD repeat domain 48 [Homo sapiens]                         37   0.025
gi|221219020 NYD-SP11 protein [Homo sapiens]                           36   0.055
gi|113865883 WD repeat domain 38 [Homo sapiens]                        36   0.055
gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [H...    36   0.055
gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [H...    36   0.055
gi|83779014 katanin p80 subunit B 1 [Homo sapiens]                     35   0.072
gi|4759276 RNA, U3 small nucleolar interacting protein 2 [Homo s...    35   0.12 
gi|21703352 myofibrillogenesis regulator 1 isoform 2 [Homo sapiens]    35   0.12 
gi|116642887 myofibrillogenesis regulator 1 isoform 1 [Homo sapi...    35   0.12 
gi|94400919 WD repeat domain 90 [Homo sapiens]                         35   0.12 
gi|13324688 bromodomain and WD repeat domain containing 2 [Homo ...    35   0.12 
gi|23199987 WD repeat domain 5B [Homo sapiens]                         35   0.12 
gi|4503513 eukaryotic translation initiation factor 3, subunit 2...    34   0.16 
gi|66932902 SREBF chaperone protein [Homo sapiens]                     33   0.27 
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ...    33   0.27 
gi|14149696 SEC31 homolog B [Homo sapiens]                             33   0.27 
gi|5174447 guanine nucleotide binding protein (G protein), beta ...    33   0.36 
gi|16554629 WD repeat domain 5 [Homo sapiens]                          33   0.36 
gi|16554627 WD repeat domain 5 [Homo sapiens]                          33   0.36 
gi|22749275 CDC20 cell division cycle 20 homolog B isoform 1 [Ho...    33   0.36 
gi|224593764 CDC20 cell division cycle 20 homolog B isoform 2 [H...    33   0.36 
gi|22749037 WD repeat domain 65 [Homo sapiens]                         33   0.36 

>gi|14149771 WD repeat domain 54 [Homo sapiens]
          Length = 334

 Score =  688 bits (1775), Expect = 0.0
 Identities = 334/334 (100%), Positives = 334/334 (100%)

Query: 1   MFRWERSIPLRGSAAALCNNLSVLQLPARNLTYFGVVHGPSAQLLSAAPEGVPLAQRQLH 60
           MFRWERSIPLRGSAAALCNNLSVLQLPARNLTYFGVVHGPSAQLLSAAPEGVPLAQRQLH
Sbjct: 1   MFRWERSIPLRGSAAALCNNLSVLQLPARNLTYFGVVHGPSAQLLSAAPEGVPLAQRQLH 60

Query: 61  AKEGAGVSPPLITQVHWCVLPFRVLLVLTSHRGIQMYESNGYTMVYWHALDSGDASPVQA 120
           AKEGAGVSPPLITQVHWCVLPFRVLLVLTSHRGIQMYESNGYTMVYWHALDSGDASPVQA
Sbjct: 61  AKEGAGVSPPLITQVHWCVLPFRVLLVLTSHRGIQMYESNGYTMVYWHALDSGDASPVQA 120

Query: 121 VFARGIAASGHFICVGTWSGRVLVFDIPAKGPNIVLSEELAGHQMPITDIATEPAQGQDC 180
           VFARGIAASGHFICVGTWSGRVLVFDIPAKGPNIVLSEELAGHQMPITDIATEPAQGQDC
Sbjct: 121 VFARGIAASGHFICVGTWSGRVLVFDIPAKGPNIVLSEELAGHQMPITDIATEPAQGQDC 180

Query: 181 VADMVTADDSGLLCVWRSGPEFTLLTRIPGFGVPCPSVQLWQGIIAAGYGNGQVHLYEAT 240
           VADMVTADDSGLLCVWRSGPEFTLLTRIPGFGVPCPSVQLWQGIIAAGYGNGQVHLYEAT
Sbjct: 181 VADMVTADDSGLLCVWRSGPEFTLLTRIPGFGVPCPSVQLWQGIIAAGYGNGQVHLYEAT 240

Query: 241 TGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVHIWKLSRNPESGYIEVEHCHGECV 300
           TGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVHIWKLSRNPESGYIEVEHCHGECV
Sbjct: 241 TGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVHIWKLSRNPESGYIEVEHCHGECV 300

Query: 301 ADTQLCGARFCDSSGNSFAVTGYDLAEIRRFSSV 334
           ADTQLCGARFCDSSGNSFAVTGYDLAEIRRFSSV
Sbjct: 301 ADTQLCGARFCDSSGNSFAVTGYDLAEIRRFSSV 334


>gi|215272341 WD repeat domain 58 isoform 2 [Homo sapiens]
          Length = 296

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 45/191 (23%), Positives = 75/191 (39%), Gaps = 15/191 (7%)

Query: 121 VFARGIAASGHFICVGTWSGRVLVFDIPAKGPNIVLSEE------LAGHQMPITDIATEP 174
           +F++ ++  G F+  G   G++ +F + +   +    E          H  P+  + +  
Sbjct: 27  IFSQSVSPCGKFLAAGNNYGQIAIFSLSSALSSEAKEESKKPVVTFQAHDGPVYSMVSTD 86

Query: 175 ----AQGQDCVADMVTAD--DSGLLCVWRSGPEFTLLTRIPGFGVPCPSVQLWQGIIAAG 228
               + G   V   + A+    G   +WR  P +     +P        V     +I AG
Sbjct: 87  RHLLSAGDGEVKAWLWAEMLKKGCKELWRRQPPYRTSLEVPEINALL-LVPKENSLILAG 145

Query: 229 YGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVHIWKLSRNPESG 288
            G+ Q+H  +  TG     +  H   I  L L     ++LS GED  V +W L    E  
Sbjct: 146 -GDCQLHTMDLETGTFTRVLRGHTDYIHCLALRERSPEVLSGGEDGAVRLWDLRTAKEVQ 204

Query: 289 YIEVEHCHGEC 299
            IEV + H EC
Sbjct: 205 TIEV-YKHEEC 214


>gi|31543164 WD repeat domain 58 isoform 1 [Homo sapiens]
          Length = 341

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 45/191 (23%), Positives = 75/191 (39%), Gaps = 15/191 (7%)

Query: 121 VFARGIAASGHFICVGTWSGRVLVFDIPAKGPNIVLSEE------LAGHQMPITDIATEP 174
           +F++ ++  G F+  G   G++ +F + +   +    E          H  P+  + +  
Sbjct: 27  IFSQSVSPCGKFLAAGNNYGQIAIFSLSSALSSEAKEESKKPVVTFQAHDGPVYSMVSTD 86

Query: 175 ----AQGQDCVADMVTAD--DSGLLCVWRSGPEFTLLTRIPGFGVPCPSVQLWQGIIAAG 228
               + G   V   + A+    G   +WR  P +     +P        V     +I AG
Sbjct: 87  RHLLSAGDGEVKAWLWAEMLKKGCKELWRRQPPYRTSLEVPEINALL-LVPKENSLILAG 145

Query: 229 YGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVHIWKLSRNPESG 288
            G+ Q+H  +  TG     +  H   I  L L     ++LS GED  V +W L    E  
Sbjct: 146 -GDCQLHTMDLETGTFTRVLRGHTDYIHCLALRERSPEVLSGGEDGAVRLWDLRTAKEVQ 204

Query: 289 YIEVEHCHGEC 299
            IEV + H EC
Sbjct: 205 TIEV-YKHEEC 214


>gi|56243583 WD repeat domain 18 [Homo sapiens]
          Length = 432

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 16/48 (33%), Positives = 27/48 (56%)

Query: 234 VHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVHIWKL 281
           +HL+E +TGNL V ++ H + +  L    +    +S G+D  V +W L
Sbjct: 103 IHLWEVSTGNLLVILSRHYQDVSCLQFTGDSSHFISGGKDCLVLVWSL 150


>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
            sapiens]
          Length = 3526

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 26/110 (23%), Positives = 48/110 (43%), Gaps = 9/110 (8%)

Query: 184  MVTADDSGLLCVWRSGPE------FTLLTRIPGFG--VPCPSVQLWQGIIAAGYGNGQVH 235
            ++T   S ++CVW  G         TL   + G    V C +  L   II +G  +    
Sbjct: 3093 VITGGTSTVVCVWEMGTSKEKAKTVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCI 3152

Query: 236  LYEATTGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVHIWKLSRNP 285
            +++    +   Q+  H   + AL +    G ++S    T++H+W ++ NP
Sbjct: 3153 IWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCA-GTYIHVWSINGNP 3201


>gi|118402582 cell division cycle 20 [Homo sapiens]
          Length = 499

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 2/71 (2%)

Query: 224 IIAAGYGNGQVHLYEATTGNLHVQ-INAHARAICALDLASEVGKLLSAGEDTFVHIWKLS 282
           I+++G  +G +H ++      HV  ++ H++ +C L  A +   L S G D  V++W  S
Sbjct: 280 ILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWP-S 338

Query: 283 RNPESGYIEVE 293
              E G++ ++
Sbjct: 339 APGEGGWVPLQ 349


>gi|5803221 WD repeat-containing protein 3 [Homo sapiens]
          Length = 943

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 17/55 (30%), Positives = 28/55 (50%)

Query: 225 IAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVHIW 279
           +A GY +G + ++   +G  +V  N H  AI  L      G+L S  +DT + +W
Sbjct: 80  LAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVW 134



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 16/55 (29%), Positives = 29/55 (52%)

Query: 225 IAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVHIW 279
           +  G   G++ LY+  +GNL   I+AH  A+ ++ L+ +    ++ G D  V  W
Sbjct: 469 VVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFW 523



 Score = 28.9 bits (63), Expect = 6.7
 Identities = 19/89 (21%), Positives = 35/89 (39%)

Query: 213 VPCPSVQLWQGIIAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAGE 272
           V C  +     +IA G  +  V ++    G+ H  + AH  ++  L    +     +AG+
Sbjct: 594 VICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGK 653

Query: 273 DTFVHIWKLSRNPESGYIEVEHCHGECVA 301
           D  +  W   +      +E  H    C+A
Sbjct: 654 DHKIKQWDADKFEHIQTLEGHHQEIWCLA 682


>gi|53759148 retinoblastoma binding protein 5 [Homo sapiens]
          Length = 538

 Score = 37.7 bits (86), Expect = 0.014
 Identities = 17/59 (28%), Positives = 32/59 (54%)

Query: 221 WQGIIAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVHIW 279
           W  ++A G  +G++ +++  T  +   I+AH   +C+L  + +  KL+SA  D  V  W
Sbjct: 35  WGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQW 93


>gi|18874090 WD repeat domain 48 [Homo sapiens]
          Length = 677

 Score = 37.0 bits (84), Expect = 0.025
 Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 9/81 (11%)

Query: 235 HLYEATTGNLHVQINAHAR---------AICALDLASEVGKLLSAGEDTFVHIWKLSRNP 285
           H  + T G   VQ++   R          + AL L   + +L +AG D+ + IW ++++ 
Sbjct: 4   HHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHK 63

Query: 286 ESGYIEVEHCHGECVADTQLC 306
           +  YI     H + V D  LC
Sbjct: 64  QDPYIASMEHHTDWVNDIVLC 84


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 35.8 bits (81), Expect = 0.055
 Identities = 31/138 (22%), Positives = 51/138 (36%), Gaps = 16/138 (11%)

Query: 159 ELAGHQMPITDIATEPAQGQDCVADMVTADDSGLLCVW--------------RSGPEFTL 204
           EL G  + I  + + P  G + V D+V    SG L                 + G     
Sbjct: 139 ELGGTGLQIAHMVSMP--GDELVQDIVLNGPSGSLLALCETVVRVLMHQGKGQLGEVKRF 196

Query: 205 LTRIPGFGVPCPSVQLWQGIIAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEV 264
            +   G  + C      QG + AG   G++ ++    G+      AH   +  +    E 
Sbjct: 197 TSTSSGSSITCCFTCFDQGFLYAGNQAGEIQVWSLQQGHPLHSFQAHQSGVICIRSRPEA 256

Query: 265 GKLLSAGEDTFVHIWKLS 282
             LL+AG D+ +  W L+
Sbjct: 257 HTLLTAGSDSLIKEWNLT 274


>gi|113865883 WD repeat domain 38 [Homo sapiens]
          Length = 314

 Score = 35.8 bits (81), Expect = 0.055
 Identities = 15/57 (26%), Positives = 32/57 (56%)

Query: 223 GIIAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVHIW 279
           G++A+G  +  +H+++ TT +L +Q+  H   + ++  + +   L SAG    V +W
Sbjct: 204 GLLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVW 260



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 16/57 (28%), Positives = 30/57 (52%)

Query: 225 IAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVHIWKL 281
           +A+G  + +V L++  +G +   +  H  +I + D +  V  L +   D+ VHIW L
Sbjct: 120 LASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDL 176


>gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [Homo
           sapiens]
          Length = 532

 Score = 35.8 bits (81), Expect = 0.055
 Identities = 15/61 (24%), Positives = 36/61 (59%), Gaps = 2/61 (3%)

Query: 224 IIAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVHIWKLSR 283
           ++ +G  +G+V +++  +GN+ + ++AH   + A+ +  +  K++S GE+  V +W    
Sbjct: 381 LMVSGNMDGRVRIHDLRSGNIALSLSAHQLRVSAVQM--DDWKIVSGGEEGLVSVWDYRM 438

Query: 284 N 284
           N
Sbjct: 439 N 439


>gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [Homo
           sapiens]
          Length = 598

 Score = 35.8 bits (81), Expect = 0.055
 Identities = 15/61 (24%), Positives = 36/61 (59%), Gaps = 2/61 (3%)

Query: 224 IIAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVHIWKLSR 283
           ++ +G  +G+V +++  +GN+ + ++AH   + A+ +  +  K++S GE+  V +W    
Sbjct: 447 LMVSGNMDGRVRIHDLRSGNIALSLSAHQLRVSAVQM--DDWKIVSGGEEGLVSVWDYRM 504

Query: 284 N 284
           N
Sbjct: 505 N 505


>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
          Length = 655

 Score = 35.4 bits (80), Expect = 0.072
 Identities = 26/128 (20%), Positives = 55/128 (42%), Gaps = 7/128 (5%)

Query: 158 EELAGHQMPITDIATEPAQGQDCVADMVTADDSGLLCVWRSGPEFTLLTRIPGFGVPCPS 217
           +E+  H   ++ +    A G+     + T  D   + +W       +++ + G   P  S
Sbjct: 14  QEIVAHASNVSSLVLGKASGRL----LATGGDDCRVNLWSINKPNCIMS-LTGHTSPVES 68

Query: 218 VQLW--QGIIAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAGEDTF 275
           V+L   + +I AG  +G + +++     +   +  H   IC+LD       + S  +DT 
Sbjct: 69  VRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTN 128

Query: 276 VHIWKLSR 283
           + +W + R
Sbjct: 129 IKLWDIRR 136


>gi|4759276 RNA, U3 small nucleolar interacting protein 2 [Homo
           sapiens]
          Length = 475

 Score = 34.7 bits (78), Expect = 0.12
 Identities = 39/168 (23%), Positives = 65/168 (38%), Gaps = 20/168 (11%)

Query: 160 LAGHQMPITDIATEPAQGQDCVADMVTADDSGLLCVW--RSGPEFTLLTRI--------P 209
           L GHQ+ IT +   P    D  A    A D  ++  W   SG +  ++ R         P
Sbjct: 142 LRGHQLSITCLVVTP----DDSAIFSAAKDCSII-KWSVESGRKLHVIPRAKKGAEGKPP 196

Query: 210 GFG--VPCPSVQLWQGIIAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKL 267
           G    V C ++      +A+G  +  + ++EA +         H  A+  L       +L
Sbjct: 197 GHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQL 256

Query: 268 LSAGEDTFVHIWKLSRNPESGYIEVEHCHGECVADTQLCGARFCDSSG 315
            S   D  V +W ++   E+ Y+E    H + VA         C ++G
Sbjct: 257 YSTSHDRSVKVWNVA---ENSYVETLFGHQDAVAALDALSRECCVTAG 301


>gi|21703352 myofibrillogenesis regulator 1 isoform 2 [Homo sapiens]
          Length = 361

 Score = 34.7 bits (78), Expect = 0.12
 Identities = 42/146 (28%), Positives = 58/146 (39%), Gaps = 8/146 (5%)

Query: 17  LCNNLSVLQLPARNLTYFGVVHGPSAQLLSAAPEGVPLAQRQLHAKEGAGVSPPLITQVH 76
           L N + VL +P  +  Y  ++    AQL  A     P A +    KEG  +   L T  H
Sbjct: 91  LFNGVKVLPIPVLSDNYSYLIIDTQAQLAVAVDPSDPRAVQASIEKEGVTLVAILCTHKH 150

Query: 77  WCVLPFRVLLVLTSHRGIQMYESNGYTMVY-WHALDSGDASPVQAVFARGIAASGHFICV 135
           W        L    HR  ++Y S    + Y  H L   D   V  +  R +A  GH    
Sbjct: 151 WDHSGGNRDL-SRRHRDCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGH---- 205

Query: 136 GTWSGRVLVFD-IPAKGPNIVLSEEL 160
            T    V + D  P KGP+ + S +L
Sbjct: 206 -TQGHLVYLLDGEPYKGPSCLFSGDL 230


>gi|116642887 myofibrillogenesis regulator 1 isoform 1 [Homo
           sapiens]
          Length = 385

 Score = 34.7 bits (78), Expect = 0.12
 Identities = 42/146 (28%), Positives = 58/146 (39%), Gaps = 8/146 (5%)

Query: 17  LCNNLSVLQLPARNLTYFGVVHGPSAQLLSAAPEGVPLAQRQLHAKEGAGVSPPLITQVH 76
           L N + VL +P  +  Y  ++    AQL  A     P A +    KEG  +   L T  H
Sbjct: 115 LFNGVKVLPIPVLSDNYSYLIIDTQAQLAVAVDPSDPRAVQASIEKEGVTLVAILCTHKH 174

Query: 77  WCVLPFRVLLVLTSHRGIQMYESNGYTMVY-WHALDSGDASPVQAVFARGIAASGHFICV 135
           W        L    HR  ++Y S    + Y  H L   D   V  +  R +A  GH    
Sbjct: 175 WDHSGGNRDL-SRRHRDCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGH---- 229

Query: 136 GTWSGRVLVFD-IPAKGPNIVLSEEL 160
            T    V + D  P KGP+ + S +L
Sbjct: 230 -TQGHLVYLLDGEPYKGPSCLFSGDL 254


>gi|94400919 WD repeat domain 90 [Homo sapiens]
          Length = 1748

 Score = 34.7 bits (78), Expect = 0.12
 Identities = 33/152 (21%), Positives = 69/152 (45%), Gaps = 18/152 (11%)

Query: 135  VGTWSGRVLVFDIPAKGPNIVLSEELAGHQMPITDIATEPAQGQDCVADMVTADDSGLLC 194
            VGT +G  L F   A+G +  L   ++GH+  + ++   P +         T  + G + 
Sbjct: 1410 VGTTAG-TLWFVSWAEGTSTRL---ISGHRSKVNEVVFSPGESH-----CATCSEDGSVR 1460

Query: 195  VWRSGP-----EFTLLTR---IPGFGVPCPSVQLWQGIIAAGYGNGQVHLYEATTGNLHV 246
            VW         +F +L +      +  PC   +  Q  +AAGYG+G + ++  +   + +
Sbjct: 1461 VWALASMELVIQFQVLNQSCLCLAWSPPCCG-RPEQQRLAAGYGDGSLRIFSVSRTAMEL 1519

Query: 247  QINAHARAICALDLASEVGKLLSAGEDTFVHI 278
            +++ H  A+  +  +++   +LS  +D  V +
Sbjct: 1520 KMHPHPVALTTVAFSTDGQTVLSGDKDGLVAV 1551


>gi|13324688 bromodomain and WD repeat domain containing 2 [Homo
           sapiens]
          Length = 1224

 Score = 34.7 bits (78), Expect = 0.12
 Identities = 13/46 (28%), Positives = 29/46 (63%)

Query: 217 SVQLWQGIIAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLAS 262
           +++++Q ++A G  NG V +Y  T+G LH +++ H+  +  ++  S
Sbjct: 480 NIKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTS 525


>gi|23199987 WD repeat domain 5B [Homo sapiens]
          Length = 330

 Score = 34.7 bits (78), Expect = 0.12
 Identities = 30/122 (24%), Positives = 51/122 (41%), Gaps = 8/122 (6%)

Query: 160 LAGHQMPITDIATEPAQGQDCVADMVTADDSGLLCVW--RSGPEFTLLTRIPGFGVPCPS 217
           L GH + I+D+A      +     +V+A D   L +W  RSG     L     + V C +
Sbjct: 79  LYGHNLEISDVAWSSDSSR-----LVSASDDKTLKLWDVRSGKCLKTLKGHSNY-VFCCN 132

Query: 218 VQLWQGIIAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVH 277
                 +I +G  +  V ++E  TG     ++AH+  + A+        ++S   D    
Sbjct: 133 FNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCR 192

Query: 278 IW 279
           IW
Sbjct: 193 IW 194


>gi|4503513 eukaryotic translation initiation factor 3, subunit 2
           beta, 36kDa [Homo sapiens]
          Length = 325

 Score = 34.3 bits (77), Expect = 0.16
 Identities = 17/72 (23%), Positives = 37/72 (51%), Gaps = 7/72 (9%)

Query: 209 PGFGVPCPSVQLWQGI-------IAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLA 261
           P   +PC   ++   +       I AG+ +G+++ Y A +G + V +  H+R I  + L+
Sbjct: 138 PYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLS 197

Query: 262 SEVGKLLSAGED 273
            ++   ++A +D
Sbjct: 198 RDMTMFVTASKD 209


>gi|66932902 SREBF chaperone protein [Homo sapiens]
          Length = 1279

 Score = 33.5 bits (75), Expect = 0.27
 Identities = 33/121 (27%), Positives = 56/121 (46%), Gaps = 11/121 (9%)

Query: 163  HQMPITDIATEPAQGQDCVADMVTADDSGLLCVWRSGPEFTLLTRIPGFGVPCPSVQLWQ 222
            HQ PIT  A + A G+     +VT      L V+R      L T + G      +V + Q
Sbjct: 1078 HQKPIT--ALKAAAGR-----LVTGSQDHTLRVFRLEDSCCLFT-LQGHSGAITTVYIDQ 1129

Query: 223  G-IIAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVHIWKL 281
              ++A+G  +G + L++  TG+    + AH   + +L   +    ++S+G D  + IW  
Sbjct: 1130 TMVLASGGQDGAICLWDVLTGSRVSHVFAHRGDVTSLTCTTSC--VISSGLDDLISIWDR 1187

Query: 282  S 282
            S
Sbjct: 1188 S 1188


>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
           sapiens]
          Length = 421

 Score = 33.5 bits (75), Expect = 0.27
 Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 1/61 (1%)

Query: 222 QGIIAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLL-SAGEDTFVHIWK 280
           Q ++A G  NG++ +++  TG L + +  H   +  L  A +   +L SA  D  + +W 
Sbjct: 140 QLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWD 199

Query: 281 L 281
           L
Sbjct: 200 L 200


>gi|14149696 SEC31 homolog B [Homo sapiens]
          Length = 1179

 Score = 33.5 bits (75), Expect = 0.27
 Identities = 25/67 (37%), Positives = 34/67 (50%), Gaps = 7/67 (10%)

Query: 223 GIIAAGYGNGQVHLYEAT----TGNLHV--QINAHARAICALDLASEVGKLLSAG-EDTF 275
           G+I  G  NG + LY  T    +G   V  Q   H  A+ ALDL    G LL++G  D+ 
Sbjct: 86  GVIVGGGDNGMLILYNVTHILSSGKEPVIAQKQKHTGAVRALDLNPFQGNLLASGASDSE 145

Query: 276 VHIWKLS 282
           + IW L+
Sbjct: 146 IFIWDLN 152


>gi|5174447 guanine nucleotide binding protein (G protein), beta
           polypeptide 2-like 1 [Homo sapiens]
          Length = 317

 Score = 33.1 bits (74), Expect = 0.36
 Identities = 39/184 (21%), Positives = 78/184 (42%), Gaps = 30/184 (16%)

Query: 154 IVLSEELAGHQMPITDIATEPAQGQDCVADMVTADDSGLLCVWRSGPEFTLLTRIPGFGV 213
           + L   L GH   +T IAT P Q  D +   ++A     + +W+   + T       +G+
Sbjct: 5   MTLRGTLKGHNGWVTQIATTP-QFPDMI---LSASRDKTIIMWKLTRDET------NYGI 54

Query: 214 PCPSVQLWQGIIA------------AGYGNGQVHLYEATTGNLHVQINAHARAICALDLA 261
           P  +++     ++            +G  +G + L++ TTG    +   H + + ++  +
Sbjct: 55  PQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFS 114

Query: 262 SEVGKLLSAGEDTFVHIWKLSRNPESGYIEVEHCHGECVADTQLCGARFCDSSGNSFAVT 321
           S+  +++S   D  + +W  +      Y   +  H E V+    C  RF  +S N   V+
Sbjct: 115 SDNRQIVSGSRDKTIKLW--NTLGVCKYTVQDESHSEWVS----C-VRFSPNSSNPIIVS 167

Query: 322 -GYD 324
            G+D
Sbjct: 168 CGWD 171


>gi|16554629 WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score = 33.1 bits (74), Expect = 0.36
 Identities = 27/122 (22%), Positives = 52/122 (42%), Gaps = 8/122 (6%)

Query: 160 LAGHQMPITDIATEPAQGQDCVADMVTADDSGLLCVWRSGPEFTLLTRIPGFG--VPCPS 217
           ++GH++ I+D+A            +V+A D   L +W       L T + G    V C +
Sbjct: 83  ISGHKLGISDVAWSSDSNL-----LVSASDDKTLKIWDVSSGKCLKT-LKGHSNYVFCCN 136

Query: 218 VQLWQGIIAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVH 277
                 +I +G  +  V +++  TG     + AH+  + A+    +   ++S+  D    
Sbjct: 137 FNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCR 196

Query: 278 IW 279
           IW
Sbjct: 197 IW 198


>gi|16554627 WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score = 33.1 bits (74), Expect = 0.36
 Identities = 27/122 (22%), Positives = 52/122 (42%), Gaps = 8/122 (6%)

Query: 160 LAGHQMPITDIATEPAQGQDCVADMVTADDSGLLCVWRSGPEFTLLTRIPGFG--VPCPS 217
           ++GH++ I+D+A            +V+A D   L +W       L T + G    V C +
Sbjct: 83  ISGHKLGISDVAWSSDSNL-----LVSASDDKTLKIWDVSSGKCLKT-LKGHSNYVFCCN 136

Query: 218 VQLWQGIIAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVH 277
                 +I +G  +  V +++  TG     + AH+  + A+    +   ++S+  D    
Sbjct: 137 FNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCR 196

Query: 278 IW 279
           IW
Sbjct: 197 IW 198


>gi|22749275 CDC20 cell division cycle 20 homolog B isoform 1 [Homo
           sapiens]
          Length = 515

 Score = 33.1 bits (74), Expect = 0.36
 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 2/57 (3%)

Query: 224 IIAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAG-EDTFVHIW 279
           I+++G   G+V+ ++      HV    H +A+CAL  + + G+LLS+G  D  + IW
Sbjct: 327 ILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPD-GRLLSSGCSDGLLTIW 382


>gi|224593764 CDC20 cell division cycle 20 homolog B isoform 2 [Homo
           sapiens]
          Length = 477

 Score = 33.1 bits (74), Expect = 0.36
 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 2/57 (3%)

Query: 224 IIAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAG-EDTFVHIW 279
           I+++G   G+V+ ++      HV    H +A+CAL  + + G+LLS+G  D  + IW
Sbjct: 327 ILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPD-GRLLSSGCSDGLLTIW 382


>gi|22749037 WD repeat domain 65 [Homo sapiens]
          Length = 698

 Score = 33.1 bits (74), Expect = 0.36
 Identities = 19/78 (24%), Positives = 32/78 (41%)

Query: 223 GIIAAGYGNGQVHLYEATTGNLHVQINAHARAICALDLASEVGKLLSAGEDTFVHIWKLS 282
           G + A      +H+Y  T+      +  H   I ++   ++  KL+S G D  V+ W LS
Sbjct: 483 GHLFAAVNGNVIHVYTTTSLENISSLKGHTGKIRSIVWNADDSKLISGGTDGAVYEWNLS 542

Query: 283 RNPESGYIEVEHCHGECV 300
                    ++ C   CV
Sbjct: 543 TGKRETECVLKSCSYNCV 560


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,537,465
Number of Sequences: 37866
Number of extensions: 627918
Number of successful extensions: 1590
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 1497
Number of HSP's gapped (non-prelim): 136
length of query: 334
length of database: 18,247,518
effective HSP length: 103
effective length of query: 231
effective length of database: 14,347,320
effective search space: 3314230920
effective search space used: 3314230920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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