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Search of human proteins with 87196600
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|87196600 polyserase 3 [Homo sapiens]
(553 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|87196600 polyserase 3 [Homo sapiens] 1172 0.0
gi|58218970 protease, serine, 36 [Homo sapiens] 318 6e-87
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 210 3e-54
gi|13994276 marapsin [Homo sapiens] 172 6e-43
gi|117956391 protease, serine, 33 [Homo sapiens] 172 7e-43
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 167 2e-41
gi|4506153 prostasin preproprotein [Homo sapiens] 165 1e-40
gi|11545839 protease, serine, 22 [Homo sapiens] 154 2e-37
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 142 6e-34
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 138 2e-32
gi|11415040 matriptase [Homo sapiens] 137 3e-32
gi|40254871 transmembrane protease, serine 11E [Homo sapiens] 135 7e-32
gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens] 135 7e-32
gi|205360905 testis-specific serine protease 1 [Homo sapiens] 134 3e-31
gi|33695155 hepsin [Homo sapiens] 133 5e-31
gi|4504481 hepsin [Homo sapiens] 133 5e-31
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 133 5e-31
gi|4505881 plasminogen [Homo sapiens] 132 6e-31
gi|5803197 testisin isoform 1 [Homo sapiens] 130 2e-30
gi|21614531 testisin isoform 2 [Homo sapiens] 130 2e-30
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 130 4e-30
gi|110815798 ovochymase 1 [Homo sapiens] 129 5e-30
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 127 2e-29
gi|110578663 hypothetical protein LOC203074 [Homo sapiens] 125 1e-28
gi|34098976 marapsin 2 [Homo sapiens] 125 1e-28
gi|4503627 coagulation factor XI precursor [Homo sapiens] 124 2e-28
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] 124 3e-28
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 122 7e-28
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 122 7e-28
gi|194018492 transmembrane protease, serine 11F [Homo sapiens] 122 7e-28
>gi|87196600 polyserase 3 [Homo sapiens]
Length = 553
Score = 1172 bits (3032), Expect = 0.0
Identities = 553/553 (100%), Positives = 553/553 (100%)
Query: 1 MKWCWGPVLLIAGATVLMEGLQAAQRACGQRGPGPPKPQEGNTVPGEWPWQASVRRQGAH 60
MKWCWGPVLLIAGATVLMEGLQAAQRACGQRGPGPPKPQEGNTVPGEWPWQASVRRQGAH
Sbjct: 1 MKWCWGPVLLIAGATVLMEGLQAAQRACGQRGPGPPKPQEGNTVPGEWPWQASVRRQGAH 60
Query: 61 ICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAY 120
ICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAY
Sbjct: 61 ICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAY 120
Query: 121 NHYSQGSDLALLQLAHPTTHTPLCLPQPAHRFPFGASCWATGWDQDTSDAPGTLRNLRLR 180
NHYSQGSDLALLQLAHPTTHTPLCLPQPAHRFPFGASCWATGWDQDTSDAPGTLRNLRLR
Sbjct: 121 NHYSQGSDLALLQLAHPTTHTPLCLPQPAHRFPFGASCWATGWDQDTSDAPGTLRNLRLR 180
Query: 181 LISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQA 240
LISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQA
Sbjct: 181 LISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQA 240
Query: 241 GIISFASSCAQEDAPVLLTNTAAHSSWLQARVQGAAFLAQSPETPEMSDEDSCVACGSLR 300
GIISFASSCAQEDAPVLLTNTAAHSSWLQARVQGAAFLAQSPETPEMSDEDSCVACGSLR
Sbjct: 241 GIISFASSCAQEDAPVLLTNTAAHSSWLQARVQGAAFLAQSPETPEMSDEDSCVACGSLR 300
Query: 301 TAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAPEEWSVGLGTRP 360
TAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAPEEWSVGLGTRP
Sbjct: 301 TAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAPEEWSVGLGTRP 360
Query: 361 EEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGERGWVLG 420
EEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGERGWVLG
Sbjct: 361 EEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGERGWVLG 420
Query: 421 RARPGAGISSLQTVPVTLLGPRACSRLHAAPGGDGSPILPGMVCTSAVGELPSCEGLSGA 480
RARPGAGISSLQTVPVTLLGPRACSRLHAAPGGDGSPILPGMVCTSAVGELPSCEGLSGA
Sbjct: 421 RARPGAGISSLQTVPVTLLGPRACSRLHAAPGGDGSPILPGMVCTSAVGELPSCEGLSGA 480
Query: 481 PLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSSLDWQVYFAEEPEPEAEP 540
PLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSSLDWQVYFAEEPEPEAEP
Sbjct: 481 PLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSSLDWQVYFAEEPEPEAEP 540
Query: 541 GSCLANISQPTSC 553
GSCLANISQPTSC
Sbjct: 541 GSCLANISQPTSC 553
>gi|58218970 protease, serine, 36 [Homo sapiens]
Length = 855
Score = 318 bits (816), Expect = 6e-87
Identities = 200/539 (37%), Positives = 275/539 (51%), Gaps = 47/539 (8%)
Query: 28 CGQRGPGPPKPQEGNTVPGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAATE- 86
CG+ P N PG WPWQ S+ G HIC GSL+A +WVL+AAHCF E
Sbjct: 38 CGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEP 97
Query: 87 LNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTT----HTP 142
WSV+LG ++G GA VAA+ +P Y+ G+DLALL+LA P + P
Sbjct: 98 AAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWP 157
Query: 143 LCLPQPAHRFPFGASCWATGW----DQDTSDAPGTLRNLRLRLISRPTCNCIYNQLHQRH 198
+CLP+ +HRF G +CWATGW + D P L+ + LRL+ TC C+Y+Q +
Sbjct: 158 VCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFN 217
Query: 199 LSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLL 258
L+ PGMLC G G + CQGDSGGP++C E G W QAGI SF C + + P +
Sbjct: 218 LTLQILPGMLCAGYPEGRRDTCQGDSGGPLVC-EEGGRWFQAGITSFGFGCGRRNRPGVF 276
Query: 259 TNTAAHSSWLQARVQGA----AFLAQSPET---PEMSDEDSCVACGSLRTAGPQAGAPSP 311
T A + +W++ +V G+ AF Q +T P+ E++C +L G +A P
Sbjct: 277 TAVATYEAWIREQVMGSEPGPAFPTQPQKTQSDPQEPREENCTI--ALPECG-KAPRPGA 333
Query: 312 WPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAPEE-------WSVGLGTRPEEWG 364
WPWEA++M G C GALVSE VL A CF+ + + W V L +RP
Sbjct: 334 WPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLLPSRPRAER 393
Query: 365 LKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGER----GWVLG 420
+ +L+ H + + D+ALL L PV L A+ RP+CLP+P+H+ G R W G
Sbjct: 394 VARLVQHENASW-DNASDLALLQLRTPVNLSAASRPVCLPHPEHYFLPGSRCRLARW--G 450
Query: 421 RARPGAGISSLQTVPVTLLGPRACSRLHAAPGG----DGSPILPGMVCTS--AVGELPSC 474
R P G +L + LLG C L+ G G P P +C + E+ SC
Sbjct: 451 RGEPALGPGAL--LEAELLGGWWCHCLYGRQGAAVPLPGDP--PHALCPAYQEKEEVGSC 506
Query: 475 EGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSSLDWQVYFAEE 533
S L+ + GTWFLAG+ F C RP F L + W+S + Y ++
Sbjct: 507 WNDSRWSLLCQEEGTWFLAGIRDFPSGC---LRPRAFFPLQTHGPWISHVTRGAYLEDQ 562
Score = 154 bits (388), Expect = 3e-37
Identities = 100/262 (38%), Positives = 126/262 (48%), Gaps = 19/262 (7%)
Query: 279 AQSPETPEMSDEDSCVACGSLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLT 338
A SP E D D S R G P WPW+ L H G CGG+L++ VL+
Sbjct: 25 ALSPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLS 84
Query: 339 AAHCFIGRQAPE---EWSVGLGTRPEEWGL--------KQLILHGAYTHPEGGYDMALLL 387
AAHCF+ E EWSV LG ++ L +++ Y+ E G D+ALL
Sbjct: 85 AAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLR 144
Query: 388 LAQPVTLGASLRPLCLPYPDHHLPDGERGWVLG-----RARPGAGISSLQTVPVTLLGPR 442
LA P +LG ++ P+CLP H G W G A P LQ V + LLG
Sbjct: 145 LASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEA 204
Query: 443 ACSRLHAAPGGDG--SPILPGMVCTS-AVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFG 499
C L++ PG ILPGM+C G +C+G SG PLV E G WF AG+ SFG
Sbjct: 205 TCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFG 264
Query: 500 DACQGPARPAVFTALPAYEDWV 521
C RP VFTA+ YE W+
Sbjct: 265 FGCGRRNRPGVFTAVATYEAWI 286
Score = 150 bits (378), Expect = 4e-36
Identities = 155/530 (29%), Positives = 216/530 (40%), Gaps = 77/530 (14%)
Query: 35 PPKPQEGNTV-----------PGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCF---- 79
P +P+E N PG WPW+A V G+ C G+LV+++WVL A CF
Sbjct: 310 PQEPREENCTIALPECGKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPN 369
Query: 80 -EKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPT 138
+ +L++W V+L S P AE V A + + SDLALLQL P
Sbjct: 370 SSDSPPRDLDAWRVLLPS------RPRAERV---ARLVQHENASWDNASDLALLQLRTPV 420
Query: 139 THT----PLCLPQPAHRFPFGASCWATGWDQ-DTSDAPGTLRNLRLRLISRPTCNCIYNQ 193
+ P+CLP P H F G+ C W + + + PG L L L+ C+C+Y +
Sbjct: 421 NLSAASRPVCLPHPEHYFLPGSRCRLARWGRGEPALGPGAL--LEAELLGGWWCHCLYGR 478
Query: 194 LHQRHLSNPARPGMLCGGPQPGVQ-GPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQE 252
P LC Q + G C DS +LC E +G W AGI F S C +
Sbjct: 479 QGAAVPLPGDPPHALCPAYQEKEEVGSCWNDSRWSLLCQE-EGTWFLAGIRDFPSGCLR- 536
Query: 253 DAPVLLTNTAAHSSWLQARVQGAAFLAQ----------SPETPEMSDEDSCVACGSLRTA 302
P H W+ +GA Q ET ACG A
Sbjct: 537 --PRAFFPLQTHGPWISHVTRGAYLEDQLAWDWGPDGEETETQTCPPHTEHGACGLRLEA 594
Query: 303 GPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFI--GRQAPEEWSVGLG--- 357
P WPW A + G C G L++ VL A HC + G V LG
Sbjct: 595 APVGVL---WPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAG 651
Query: 358 --TRPEEWGLKQLILHGAYTHPEG-GYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGE 414
+ P+ + +L++ G +ALL L+ V S P+CL +P +P G
Sbjct: 652 ASSLPQGHQVSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICL-HP-AGIPPGA 709
Query: 415 RGWVLGRARPGAGISSLQTVPVTLLGPRACSRLHAAPGGDGSPILPGMVCT-SAVGELPS 473
WVLG P + V++L R C L+ + PG +C A G+
Sbjct: 710 SCWVLGWKEPQDRVP--VAAAVSILTQRICDCLYQ------GILPPGTLCVLYAEGQENR 761
Query: 474 CEGLSGAPLVHEV-RGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVS 522
CE S PL+ ++ G+W L G+ A QG +F A+ E W+S
Sbjct: 762 CEMTSAPPLLCQMTEGSWILVGM-----AVQGSRE--LFAAIGPEEAWIS 804
Score = 98.6 bits (244), Expect = 1e-20
Identities = 79/293 (26%), Positives = 117/293 (39%), Gaps = 51/293 (17%)
Query: 1 MKWCWGPVLLIAGATVLMEGLQAAQRACGQRGPGPPKPQEGNT--------VPGEWPWQA 52
+ W WGP +G + + C PP + G V WPW A
Sbjct: 563 LAWDWGP-----------DGEETETQTC------PPHTEHGACGLRLEAAPVGVLWPWLA 605
Query: 53 SVRRQGAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSPGAEEVG-- 110
V G +C+G L+A WVL A HC + +T + V LG L P +V
Sbjct: 606 EVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSL-PQGHQVSRL 664
Query: 111 VAALQLPRAYNHYSQGSDLALLQLAHPTTHTPLCLPQPAH--RFPFGASCWATGWDQDTS 168
V +++LP+ H LALL+L+ +P LP H P GASCW GW +
Sbjct: 665 VISIRLPQ---HLGLRPPLALLELSSRVEPSPSALPICLHPAGIPPGASCWVLGWKEPQD 721
Query: 169 DAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPV 228
P + ++++ C+C+Y + PG LC G + C+ S P+
Sbjct: 722 RVPVA---AAVSILTQRICDCLYQGI--------LPPGTLCVLYAEGQENRCEMTSAPPL 770
Query: 229 LCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQARVQGAAFLAQS 281
LC +G W+ G+ A + + L +W+ V A FL S
Sbjct: 771 LCQMTEGSWILVGM-------AVQGSRELFAAIGPEEAWISQTVGEANFLPPS 816
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 210 bits (534), Expect = 3e-54
Identities = 155/583 (26%), Positives = 247/583 (42%), Gaps = 87/583 (14%)
Query: 20 GLQAAQRACGQRGPGPPKPQEGNTVPGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCF 79
GLQ A R G+ G PGE+PWQAS+R H C +++ W+++AAHCF
Sbjct: 192 GLQPAWRMAGRIVGGM------EASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCF 245
Query: 80 EKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTT 139
+ + W +G+ G V + YN + D+A+L+L P
Sbjct: 246 NEFQ--DPTKWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLP 303
Query: 140 H----TPLCLPQPAHRFPFGASCWATGWD---QDTSDAPGTLRNLRLRLISRPTCNCIYN 192
P+CLP H FP C +GW +D P L+ + L+ + C +Y
Sbjct: 304 FGRHIQPVCLPAATHIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALCASLYG 363
Query: 193 QLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQE 252
+ M+C G G CQGDSGGP++C EP G + AGI+S+ CA+
Sbjct: 364 --------HSLTDRMVCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEA 415
Query: 253 DAPVLLTNTAAHSSW-LQARVQGAAFLAQ---------------SPETPEMSDEDSCVA- 295
P + W L+A + + LA SPE+P +S +
Sbjct: 416 RRPGVYARVTRLRDWILEATTKASMPLAPTMAPAPAAPSTAWPTSPESPVVSTPTKSMQA 475
Query: 296 ----------------CGS-------LRTAGPQAGAPSPWPWEARLMHQGQLACGGALVS 332
CG+ R G A PW+ L + CG +V
Sbjct: 476 LSTVPLDWVTVPKLQECGARPAMEKPTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVG 535
Query: 333 EEAVLTAAHCFIGRQAPEEWS-------VGLGTRPEEWGLKQLILHGAYTHPEGGYDMAL 385
+ +L+AAHCF + + + +GLG P + GL++++LH Y +D+A+
Sbjct: 536 DRWLLSAAHCFNHTKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAV 595
Query: 386 LLLAQPVTLGASLRPLCLPYPDHHLPDGERGWVLGRARPGAGISS----LQTVPVTLLGP 441
L LA P+ ++P+CLP P G + + G G ++ LQ V ++
Sbjct: 596 LELASPLAFNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQ 655
Query: 442 RACSRLHAAPGGDGSPILPGMVCTSAV-GELPSCEGLSGAPLV-HEVRGTWFLAGLHSFG 499
+ CS L+ + M+C + G++ SC+G SG PL E G ++LAG+ S+G
Sbjct: 656 KTCSVLY------NFSLTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWG 709
Query: 500 DACQGPARPAVFTALPAYEDWVSSLDWQVYFAEEPEPEAEPGS 542
C +P V+T + + W+ + + +P P + P +
Sbjct: 710 IGCAQVKKPGVYTRITRLKGWILEI-----MSSQPLPMSPPST 747
Score = 140 bits (353), Expect = 3e-33
Identities = 88/237 (37%), Positives = 118/237 (49%), Gaps = 23/237 (9%)
Query: 46 GEWPWQASV-RRQGAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSP 104
GEWPWQ S+ R+ H C LVA+ W+L+AAHCF+ + W+ LG+ G
Sbjct: 836 GEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYG--DPKQWAAFLGTPFLSGAEG 893
Query: 105 GAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHT----PLCLPQPAHRFPFGASCWA 160
E V A + YN Y+ D+ALL+LA P + P+CLP+PA R P G C
Sbjct: 894 QLERV--ARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRPPDGTRCVI 951
Query: 161 TGWD--QDTSDAPGTLRNLRLRLISRPTCNCIYN-QLHQRHLSNPARPGMLCGG-PQPGV 216
TGW ++ L+ +RL+S TC Y Q+ R MLC G PQ GV
Sbjct: 952 TGWGSVREGGSMARQLQKAAVRLLSEQTCRRFYPVQISSR---------MLCAGFPQGGV 1002
Query: 217 QGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQARVQ 273
C GD+GGP+ C EP G WV G+ S+ C + P + T AA W+ +Q
Sbjct: 1003 DS-CSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQHIQ 1058
Score = 137 bits (344), Expect = 3e-32
Identities = 90/296 (30%), Positives = 126/296 (42%), Gaps = 25/296 (8%)
Query: 28 CGQRGPGPPKPQEG----NTVPGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAA 83
CG R P KP GE PWQ S++ H C ++V D W+L+AAHCF
Sbjct: 492 CGAR-PAMEKPTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHTK 550
Query: 84 ATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHT-- 141
++ + LG+ GL ++G+ + L YN DLA+L+LA P
Sbjct: 551 VEQVRAH---LGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKY 607
Query: 142 --PLCLPQPAHRFPFGASCWATGW---DQDTSDAPGTLRNLRLRLISRPTCNCIYN-QLH 195
P+CLP +FP G C +GW + + P L+ + +I + TC+ +YN L
Sbjct: 608 IQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNFSLT 667
Query: 196 QRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAP 255
R M+C G G CQGDSGGP+ C E G + AGI+S+ CAQ P
Sbjct: 668 DR---------MICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKP 718
Query: 256 VLLTNTAAHSSWLQARVQGAAFLAQSPETPEMSDEDSCVACGSLRTAGPQAGAPSP 311
+ T W+ + P T M S L G P+P
Sbjct: 719 GVYTRITRLKGWILEIMSSQPLPMSPPSTTRMLATTSPRTTAGLTVPGATPSRPTP 774
Score = 118 bits (296), Expect = 1e-26
Identities = 89/260 (34%), Positives = 118/260 (45%), Gaps = 29/260 (11%)
Query: 282 PETPEMSDEDSCVACGSL-----RTAGPQAGAPSPWPWEARL-MHQGQLACGGALVSEEA 335
P+ PE + CG R G A WPW+ L + + + CG LV+E
Sbjct: 803 PDAPEATTHTQLPDCGLAPAALTRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERW 862
Query: 336 VLTAAHCFIGRQAPEEWSVGLGTRPEEWGLKQLILHGA--YTHPEGG-----YDMALLLL 388
+L+AAHCF P++W+ LGT P G + + A Y HP YD+ALL L
Sbjct: 863 LLSAAHCFDVYGDPKQWAAFLGT-PFLSGAEGQLERVARIYKHPFYNLYTLDYDVALLEL 921
Query: 389 AQPVTLGASLRPLCLPYPDHHLPDGER----GWVLGRARPGAGIS-SLQTVPVTLLGPRA 443
A PV +RP+CLP P PDG R GW G R G ++ LQ V LL +
Sbjct: 922 AGPVRRSRLVRPICLPEPAPRPPDGTRCVITGW--GSVREGGSMARQLQKAAVRLLSEQT 979
Query: 444 CSRLHAAPGGDGSPILPGMVCTS-AVGELPSCEGLSGAPLV-HEVRGTWFLAGLHSFGDA 501
C R + I M+C G + SC G +G PL E G W L G+ S+G
Sbjct: 980 CRRFYPV------QISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYG 1033
Query: 502 CQGPARPAVFTALPAYEDWV 521
C P P V+T + A W+
Sbjct: 1034 CGRPHFPGVYTRVAAVRGWI 1053
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 172 bits (437), Expect = 6e-43
Identities = 88/236 (37%), Positives = 132/236 (55%), Gaps = 12/236 (5%)
Query: 42 NTVPGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREG 101
+T GEWPWQ S++R G+H C GSL+A+ WVLTAAHCF + T L + V+LG+ Q
Sbjct: 40 DTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSL--YQVLLGARQLVQ 97
Query: 102 LSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHT----PLCLPQPAHRFPFGAS 157
P A V ++ Y + +D+AL++L P T P+CLP P+ F G +
Sbjct: 98 PGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMN 157
Query: 158 CWATGW----DQDTSDAPGTLRNLRLRLISRPTCNCIYNQ-LHQRHLSNPARPGMLCGGP 212
CW TGW ++D P L+ L + +I P CN +Y++ + + MLC G
Sbjct: 158 CWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGF 217
Query: 213 QPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWL 268
+ G + C+GDSGGP++CL W+QAG+IS+ CA+++ P + AH +W+
Sbjct: 218 EEGKKDACKGDSGGPLVCLVGQS-WLQAGVISWGEGCARQNRPGVYIRVTAHHNWI 272
Score = 104 bits (259), Expect = 2e-22
Identities = 75/251 (29%), Positives = 110/251 (43%), Gaps = 21/251 (8%)
Query: 292 SCVACGSLRT----AGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQ 347
+ ACG R G Q WPW+ + G CGG+L++E+ VLTAAHCF
Sbjct: 22 AATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTS 81
Query: 348 APEEWSVGLGTR------PEEW--GLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLR 399
+ V LG R P ++Q+ + Y D+AL+ L PV +
Sbjct: 82 ETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYIL 141
Query: 400 PLCLPYPDHHLPDGERGWVLGRARPG-----AGISSLQTVPVTLLGPRACSRLHAAP--- 451
P+CLP P G WV G P LQ + V ++ C+ L++
Sbjct: 142 PVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEF 201
Query: 452 GGDGSPILPGMVCTS-AVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAV 510
G I M+C G+ +C+G SG PLV V +W AG+ S+G+ C RP V
Sbjct: 202 GYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGV 261
Query: 511 FTALPAYEDWV 521
+ + A+ +W+
Sbjct: 262 YIRVTAHHNWI 272
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 172 bits (436), Expect = 7e-43
Identities = 106/274 (38%), Positives = 143/274 (52%), Gaps = 15/274 (5%)
Query: 8 VLLIAGATVLMEGLQAAQRACGQRGPGPPKPQEGNTVPGEWPWQASVRRQGAHICSGSLV 67
+LL+ GA +G ++A ACGQ + GEWPWQAS++ +GAH+C GSL+
Sbjct: 11 LLLVLGAAGT-QGRKSA--ACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLI 67
Query: 68 ADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGS 127
A WVLTAAHCF + A + V LG+L+ SP V V + LP Y+
Sbjct: 68 APQWVLTAAHCFPRRALPA--EYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARG 125
Query: 128 DLALLQLAHPTTHT----PLCLPQPAHRFPFGASCWATGWDQDTSDAP----GTLRNLRL 179
DLALLQL P + P+CLP P R P G C TGW P L+ +R+
Sbjct: 126 DLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRV 185
Query: 180 RLISRPTCNCIYN-QLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWV 238
L+ TC+ +Y+ PG LC G G + CQGDSGGP+ CL+ G WV
Sbjct: 186 PLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQ-SGSWV 244
Query: 239 QAGIISFASSCAQEDAPVLLTNTAAHSSWLQARV 272
G++S+ CA + P + T+ A +S W+QARV
Sbjct: 245 LVGVVSWGKGCALPNRPGVYTSVATYSPWIQARV 278
Score = 144 bits (362), Expect = 3e-34
Identities = 93/253 (36%), Positives = 127/253 (50%), Gaps = 27/253 (10%)
Query: 295 ACG----SLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAPE 350
ACG S R G + G WPW+A + H+G CGG+L++ + VLTAAHCF R P
Sbjct: 27 ACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPA 86
Query: 351 EWSVGLG------TRPEEWG--LKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLC 402
E+ V LG T P +++++L Y+ D+ALL L +PV L A ++P+C
Sbjct: 87 EYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVC 146
Query: 403 LPYPDHHLPDGE----RGWVLGRARPGAGISS---LQTVPVTLLGPRACSRLHAAPGGDG 455
LP P P G GW G RPG + LQ V V LL R C L+ G D
Sbjct: 147 LPVPGARPPPGTPCRVTGW--GSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHV-GADV 203
Query: 456 SP----ILPGMVCTS-AVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAV 510
+LPG +C G +C+G SG PL G+W L G+ S+G C P RP V
Sbjct: 204 PQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGV 263
Query: 511 FTALPAYEDWVSS 523
+T++ Y W+ +
Sbjct: 264 YTSVATYSPWIQA 276
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 167 bits (424), Expect = 2e-41
Identities = 89/248 (35%), Positives = 127/248 (51%), Gaps = 14/248 (5%)
Query: 28 CGQRGPGPPKPQEGNTVPGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAATEL 87
CG +GP + GEWPWQAS++ +G HIC G+L+AD WV+TAAHCF++ +
Sbjct: 568 CGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMAST 627
Query: 88 NSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHT----PL 143
W+V LG + + PG V+ L L + S D+ALLQL HP + P+
Sbjct: 628 VLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPV 687
Query: 144 CLPQPAHRFPFGASCWATGWDQDTSDAP--GTLRNLRLRLISRPTCNCIYNQLHQRHLSN 201
CLP +H F G CW TGW P L+ + ++LI + C+ +Y
Sbjct: 688 CLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRY-------- 739
Query: 202 PARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNT 261
P MLC G + G + CQGDSGGP++C G W AG++S+ C + + + T
Sbjct: 740 QVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRI 799
Query: 262 AAHSSWLQ 269
SW+Q
Sbjct: 800 TGVISWIQ 807
Score = 130 bits (327), Expect = 3e-30
Identities = 90/262 (34%), Positives = 128/262 (48%), Gaps = 26/262 (9%)
Query: 282 PETPEMSDEDSCVACG----SLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVL 337
P+ + SDE+ C CG S R G + WPW+A L +G+ CGGAL+++ V+
Sbjct: 555 PDCRDGSDEEHC-DCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVI 613
Query: 338 TAAHCF--IGRQAPEEWSVGLGT--RPEEW------GLKQLILHGAYTHPEGGYDMALLL 387
TAAHCF + W+V LG + W + +L+LH + YD+ALL
Sbjct: 614 TAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQ 673
Query: 388 LAQPVTLGASLRPLCLPYPDHHLPDGERGWVL--GRARPGAGIS-SLQTVPVTLLGPRAC 444
L PV A++RP+CLP H G W+ G R G IS +LQ V V L+ C
Sbjct: 674 LDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLC 733
Query: 445 SRLHAAPGGDGSPILPGMVCTS-AVGELPSCEGLSGAPLV-HEVRGTWFLAGLHSFGDAC 502
S ++ + P M+C G+ +C+G SG PLV + G WFLAGL S+G C
Sbjct: 734 SEVYR------YQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGC 787
Query: 503 QGPARPAVFTALPAYEDWVSSL 524
P V+T + W+ +
Sbjct: 788 GRPNYFGVYTRITGVISWIQQV 809
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 165 bits (417), Expect = 1e-40
Identities = 95/273 (34%), Positives = 140/273 (51%), Gaps = 12/273 (4%)
Query: 8 VLLIAGATVLMEGLQAAQRACGQRGPGPPKPQEGNTVPGEWPWQASVRRQGAHICSGSLV 67
+LL G G + A+ CG P + V G+WPWQ S+ +G H+C GSLV
Sbjct: 17 ILLYLGLLRSGTGAEGAEAPCGV-APQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLV 75
Query: 68 ADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGS 127
++ WVL+AAHCF E ++ V LG+ Q + S A+ + + +Y
Sbjct: 76 SEQWVLSAAHCFPSEHHKE--AYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQG 133
Query: 128 DLALLQLAHPTTHT----PLCLPQPAHRFPFGASCWATGWDQDTSD----APGTLRNLRL 179
D+ALLQL+ P T + P+CLP FP G C TGW P L+ L +
Sbjct: 134 DIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEV 193
Query: 180 RLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQ 239
LISR TCNC+YN + + + M+C G G + CQGDSGGP+ C +G W
Sbjct: 194 PLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSC-PVEGLWYL 252
Query: 240 AGIISFASSCAQEDAPVLLTNTAAHSSWLQARV 272
GI+S+ +C + P + T ++++SW+Q++V
Sbjct: 253 TGIVSWGDACGARNRPGVYTLASSYASWIQSKV 285
Score = 138 bits (347), Expect = 2e-32
Identities = 89/274 (32%), Positives = 128/274 (46%), Gaps = 21/274 (7%)
Query: 290 EDSCVACGSLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAP 349
E C R G + WPW+ + ++G CGG+LVSE+ VL+AAHCF
Sbjct: 34 EAPCGVAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHK 93
Query: 350 EEWSVGLGTR--------PEEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPL 401
E + V LG + LK +I H +Y D+ALL L++P+T +RP+
Sbjct: 94 EAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPI 153
Query: 402 CLPYPDHHLPDG----ERGWVLGRARPGAGI---SSLQTVPVTLLGPRACSRLHAAPGGD 454
CLP + P+G GW G P + LQ + V L+ C+ L+
Sbjct: 154 CLPAANASFPNGLHCTVTGW--GHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKP 211
Query: 455 GSP--ILPGMVCTSAV-GELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVF 511
P + MVC V G +C+G SG PL V G W+L G+ S+GDAC RP V+
Sbjct: 212 EEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVY 271
Query: 512 TALPAYEDWVSSLDWQVYFAEEPE-PEAEPGSCL 544
T +Y W+ S ++ P+ E++P S L
Sbjct: 272 TLASSYASWIQSKVTELQPRVVPQTQESQPDSNL 305
>gi|11545839 protease, serine, 22 [Homo sapiens]
Length = 317
Score = 154 bits (389), Expect = 2e-37
Identities = 97/284 (34%), Positives = 146/284 (51%), Gaps = 30/284 (10%)
Query: 8 VLLIAGATVLMEGLQAAQRACGQRGPGPPKPQEGNTVPG-------EWPWQASVRRQGAH 60
+LL+A +L ACG KPQ+ N V G EWPW S+++ G H
Sbjct: 21 LLLLASTAILNAARIPVPPACG-------KPQQLNRVVGGEDSTDSEWPWIVSIQKNGTH 73
Query: 61 ICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAY 120
C+GSL+ WV+TAAHCF K + +SV+LG+ Q +++VGVA ++ P
Sbjct: 74 HCAGSLLTSRWVITAAHCF-KDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVE-PHPV 131
Query: 121 NHYSQG--SDLALLQLAHPTTHT----PLCLPQPAHRFPFGASCWATGW----DQDTSDA 170
+ +G +D+AL++L + P+CLP + P CW +GW D
Sbjct: 132 YSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPH 191
Query: 171 PGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLC 230
P TL+ L++ +I C+ +Y + P MLC G G + C GDSGGP++C
Sbjct: 192 PQTLQKLKVPIIDSEVCSHLY---WRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMC 248
Query: 231 LEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQARVQG 274
+ DG W+ AGIIS+ CA+ + P + + +AH SW++ VQG
Sbjct: 249 -QVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQG 291
Score = 124 bits (311), Expect = 2e-28
Identities = 81/250 (32%), Positives = 119/250 (47%), Gaps = 21/250 (8%)
Query: 295 ACGSL----RTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGR-QAP 349
ACG R G + S WPW + G C G+L++ V+TAAHCF P
Sbjct: 40 ACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKP 99
Query: 350 EEWSVGLG--------TRPEEWGLKQLILHGAYTHPEGGY-DMALLLLAQPVTLGASLRP 400
+SV LG +R ++ G+ + H Y+ EG D+AL+ L + + + P
Sbjct: 100 YLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLP 159
Query: 401 LCLPYPDHHLPDGERGWVLGRARPGAGI-----SSLQTVPVTLLGPRACSRLHAAPGGDG 455
+CLP HLP W+ G G+ +LQ + V ++ CS L+ G G
Sbjct: 160 ICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQG 219
Query: 456 SPILPGMVCTSAV-GELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTAL 514
PI M+C + GE +C G SG PL+ +V G W LAG+ S+G+ C RP V+ +L
Sbjct: 220 -PITEDMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISL 278
Query: 515 PAYEDWVSSL 524
A+ WV +
Sbjct: 279 SAHRSWVEKI 288
>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
Length = 321
Score = 142 bits (359), Expect = 6e-34
Identities = 86/233 (36%), Positives = 122/233 (52%), Gaps = 15/233 (6%)
Query: 300 RTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAPEEWSVGLGT- 358
R G A WPW+A L + CGG+L+S + VLTAAHCF G ++ V LG
Sbjct: 37 RIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGEL 96
Query: 359 ----RPEEWGLKQLILHGAYT-HPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDG 413
P ++Q+ILH + + P D+AL+ L+ PVTL + + P+CLP G
Sbjct: 97 EITLSPHFSTVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPG 156
Query: 414 ERGWVLG-----RARPGAGISSLQTVPVTLLGPRACSRLHAAPGGDGSPILPGMVCTSAV 468
R WV G P SL+ V V+++ C R + PGG S + P M+C
Sbjct: 157 IRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGG--SILQPDMLCARGP 214
Query: 469 GELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWV 521
G+ +C+ SG PLV +V G W AG+ S+G+ C P RP V+T +PAY +W+
Sbjct: 215 GD--ACQDDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWI 265
Score = 136 bits (343), Expect = 4e-32
Identities = 94/282 (33%), Positives = 143/282 (50%), Gaps = 34/282 (12%)
Query: 6 GPVLLIAGATVLMEGLQAAQRACG--QRGPGPPKPQEGNTVP-GEWPWQASVRRQGAHIC 62
G +LL+A V L+ Q CG Q + G+ P G WPWQAS+R + H+C
Sbjct: 7 GLLLLLAVPGV---SLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRVHVC 63
Query: 63 SGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNH 122
GSL++ WVLTAAHCF + + + + V LG L+ LSP V L +
Sbjct: 64 GGSLLSPQWVLTAAHCF--SGSLNSSDYQVHLGELEIT-LSPHFSTVRQIILHSSPSGQP 120
Query: 123 YSQGSDLALLQLAHPTTHT----PLCLPQPAHRFPFGASCWATGW----DQDTSDAPGTL 174
+ G D+AL++L+ P T + P+CLP+ + F G CW TGW + + P +L
Sbjct: 121 GTSG-DIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSL 179
Query: 175 RNLRLRLISRPTCNCIYNQLHQRHLSNPA----RPGMLCGGPQPGVQGPCQGDSGGPVLC 230
R +++ ++ TC +R P +P MLC G CQ DSGGP++C
Sbjct: 180 REVKVSVVDTETC--------RRDYPGPGGSILQPDMLCA---RGPGDACQDDSGGPLVC 228
Query: 231 LEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQARV 272
+ +G WVQAGI+S+ C + + P + T A+ +W++ +
Sbjct: 229 -QVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHI 269
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 138 bits (347), Expect = 2e-32
Identities = 84/255 (32%), Positives = 121/255 (47%), Gaps = 19/255 (7%)
Query: 27 ACGQRGPGPPKPQEGN-TVPGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAAT 85
ACG R + GN ++ +WPWQAS++ QG H+C GS++ W++TAAHC
Sbjct: 206 ACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLP 265
Query: 86 ELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHT---- 141
+ SW++ +G + L A V + Y G+D+AL++LA P T
Sbjct: 266 K--SWTIQVGLVSL--LDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQ 321
Query: 142 PLCLPQPAHRFPFGASCWATGW---DQDTSDAPGTLRNLRLRLISRPTCNCIYNQLHQRH 198
P+CLP FP G CW +GW + DA L + + LIS CN H+
Sbjct: 322 PVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICN------HRDV 375
Query: 199 LSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLL 258
P MLC G G CQGDSGGP++C E W G SF CA+ + P +
Sbjct: 376 YGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQE-RRLWKLVGATSFGIGCAEVNKPGVY 434
Query: 259 TNTAAHSSWLQARVQ 273
T + W+ +++
Sbjct: 435 TRVTSFLDWIHEQME 449
Score = 135 bits (341), Expect = 7e-32
Identities = 82/245 (33%), Positives = 120/245 (48%), Gaps = 20/245 (8%)
Query: 293 CVACG-----SLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQ 347
C ACG S R G S WPW+A L QG CGG++++ ++TAAHC
Sbjct: 204 CTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLY 263
Query: 348 APEEWSVGLG-----TRPEEWGL-KQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPL 401
P+ W++ +G P L ++++ H Y G D+AL+ LA P+T ++P+
Sbjct: 264 LPKSWTIQVGLVSLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPV 323
Query: 402 CLPYPDHHLPDGERGWV--LGRARPGAGISS--LQTVPVTLLGPRACSRLHAAPGGDGSP 457
CLP + + PDG+ W G GAG +S L V L+ + C+ G
Sbjct: 324 CLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVY----GGI 379
Query: 458 ILPGMVCTS-AVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPA 516
I P M+C G + SC+G SG PLV + R W L G SFG C +P V+T + +
Sbjct: 380 ISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTS 439
Query: 517 YEDWV 521
+ DW+
Sbjct: 440 FLDWI 444
>gi|11415040 matriptase [Homo sapiens]
Length = 855
Score = 137 bits (345), Expect = 3e-32
Identities = 77/235 (32%), Positives = 118/235 (50%), Gaps = 19/235 (8%)
Query: 46 GEWPWQASVRRQG-AHICSGSLVADTWVLTAAHCFEKAAA---TELNSWSVVLGSL-QRE 100
GEWPWQ S+ G HIC SL++ W+++AAHC+ ++ W+ LG Q +
Sbjct: 624 GEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTAFLGLHDQSQ 683
Query: 101 GLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHT----PLCLPQPAHRFPFGA 156
+PG +E + + +N ++ D+ALL+L P ++ P+CLP +H FP G
Sbjct: 684 RSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPDASHVFPAGK 743
Query: 157 SCWATGWDQDTSDAPGTL--RNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQP 214
+ W TGW G L + +R+I++ TC + L P M+C G
Sbjct: 744 AIWVTGWGHTQYGGTGALILQKGEIRVINQTTCENL--------LPQQITPRMMCVGFLS 795
Query: 215 GVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQ 269
G CQGDSGGP+ +E DG QAG++S+ CAQ + P + T W++
Sbjct: 796 GGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWIK 850
Score = 119 bits (297), Expect = 9e-27
Identities = 84/260 (32%), Positives = 117/260 (45%), Gaps = 33/260 (12%)
Query: 288 SDEDSCVACG------SLRTAGPQAGAPSPWPWEARLMHQGQ-LACGGALVSEEAVLTAA 340
SDE C CG R G WPW+ L GQ CG +L+S +++AA
Sbjct: 597 SDEKDC-DCGLRSFTRQARVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAA 655
Query: 341 HCFIGRQA-----PEEWSVGLGTRPE---------EWGLKQLILHGAYTHPEGGYDMALL 386
HC+I + P +W+ LG + E LK++I H + YD+ALL
Sbjct: 656 HCYIDDRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALL 715
Query: 387 LLAQPVTLGASLRPLCLPYPDHHLPDGERGWVLGRARP---GAGISSLQTVPVTLLGPRA 443
L +P + +RP+CLP H P G+ WV G G G LQ + ++
Sbjct: 716 ELEKPAEYSSMVRPICLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVINQTT 775
Query: 444 CSRLHAAPGGDGSPILPGMVCTSAV-GELPSCEGLSGAPLVH-EVRGTWFLAGLHSFGDA 501
C L I P M+C + G + SC+G SG PL E G F AG+ S+GD
Sbjct: 776 CENLLP------QQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDG 829
Query: 502 CQGPARPAVFTALPAYEDWV 521
C +P V+T LP + DW+
Sbjct: 830 CAQRNKPGVYTRLPLFRDWI 849
>gi|40254871 transmembrane protease, serine 11E [Homo sapiens]
Length = 423
Score = 135 bits (341), Expect = 7e-32
Identities = 78/235 (33%), Positives = 120/235 (51%), Gaps = 13/235 (5%)
Query: 298 SLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAPEEW--SVG 355
SLR G WPW+A L G CG L++ +++AAHCF + P W S G
Sbjct: 189 SLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFG 248
Query: 356 LGTRPEEW--GLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDG 413
+ +P + GL+++I+H Y HP YD++L L+ PV ++ +CLP + G
Sbjct: 249 VTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPG 308
Query: 414 ERGWVLG---RARPGAGISSLQTVPVTLLGPRACSRLHAAPGGDGSPILPGMVCTSAV-G 469
+ +V G G + L+ VTL+ C+ P I P M+C ++ G
Sbjct: 309 DVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNE----PQAYNDAITPRMLCAGSLEG 364
Query: 470 ELPSCEGLSGAPLV-HEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSS 523
+ +C+G SG PLV + R W+LAG+ S+GD C P +P V+T + A DW++S
Sbjct: 365 KTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITS 419
Score = 123 bits (309), Expect = 4e-28
Identities = 73/234 (31%), Positives = 115/234 (49%), Gaps = 22/234 (9%)
Query: 46 GEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAATELNS--WSVVLGSLQREGLS 103
GEWPWQAS++ G+H C +L+ TW+++AAHCF T N W+ G +
Sbjct: 201 GEWPWQASLQWDGSHRCGATLINATWLVSAAHCF----TTYKNPARWTASFGVT----IK 252
Query: 104 PGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHTP----LCLPQPAHRFPFGASCW 159
P + G+ + + Y H S D++L +L+ P +T +CLP ++ F G +
Sbjct: 253 PSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMF 312
Query: 160 ATGWDQDTSD--APGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQ 217
TG+ +D + LR ++ LI TCN + ++ P MLC G G
Sbjct: 313 VTGFGALKNDGYSQNHLRQAQVTLIDATTCN------EPQAYNDAITPRMLCAGSLEGKT 366
Query: 218 GPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQAR 271
CQGDSGGP++ + W AGI+S+ CA+ + P + T A W+ ++
Sbjct: 367 DACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSK 420
>gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]
Length = 423
Score = 135 bits (341), Expect = 7e-32
Identities = 78/235 (33%), Positives = 120/235 (51%), Gaps = 13/235 (5%)
Query: 298 SLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAPEEW--SVG 355
SLR G WPW+A L G CG L++ +++AAHCF + P W S G
Sbjct: 189 SLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFG 248
Query: 356 LGTRPEEW--GLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDG 413
+ +P + GL+++I+H Y HP YD++L L+ PV ++ +CLP + G
Sbjct: 249 VTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPG 308
Query: 414 ERGWVLG---RARPGAGISSLQTVPVTLLGPRACSRLHAAPGGDGSPILPGMVCTSAV-G 469
+ +V G G + L+ VTL+ C+ P I P M+C ++ G
Sbjct: 309 DVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNE----PQAYNDAITPRMLCAGSLEG 364
Query: 470 ELPSCEGLSGAPLV-HEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSS 523
+ +C+G SG PLV + R W+LAG+ S+GD C P +P V+T + A DW++S
Sbjct: 365 KTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITS 419
Score = 123 bits (309), Expect = 4e-28
Identities = 73/234 (31%), Positives = 115/234 (49%), Gaps = 22/234 (9%)
Query: 46 GEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAATELNS--WSVVLGSLQREGLS 103
GEWPWQAS++ G+H C +L+ TW+++AAHCF T N W+ G +
Sbjct: 201 GEWPWQASLQWDGSHRCGATLINATWLVSAAHCF----TTYKNPARWTASFGVT----IK 252
Query: 104 PGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHTP----LCLPQPAHRFPFGASCW 159
P + G+ + + Y H S D++L +L+ P +T +CLP ++ F G +
Sbjct: 253 PSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMF 312
Query: 160 ATGWDQDTSD--APGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQ 217
TG+ +D + LR ++ LI TCN + ++ P MLC G G
Sbjct: 313 VTGFGALKNDGYSQNHLRQAQVTLIDATTCN------EPQAYNDAITPRMLCAGSLEGKT 366
Query: 218 GPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQAR 271
CQGDSGGP++ + W AGI+S+ CA+ + P + T A W+ ++
Sbjct: 367 DACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSK 420
>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
Length = 318
Score = 134 bits (336), Expect = 3e-31
Identities = 80/257 (31%), Positives = 119/257 (46%), Gaps = 18/257 (7%)
Query: 25 QRACGQRGPGPPKPQEGNTVPGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAA 84
+ ACG R + G WPWQAS+R + H C GSL++ WVL+AAHCF+K
Sbjct: 43 EEACGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYY 102
Query: 85 TELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQG---SDLALLQLAHPTTHT 141
+ W+V LG L N + G +D+ALL+LA T+
Sbjct: 103 P--SEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYN 160
Query: 142 ----PLCLPQPAHRFPFGASCWATGWDQDTSDA-----PGTLRNLRLRLISRPTCNCIYN 192
P+C+ F CW TGW + P LR ++ +++ CN ++
Sbjct: 161 AYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFE 220
Query: 193 QLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQE 252
Q R + M C G + G C+GDSGGP++C + DG W Q GI+S+ C Q
Sbjct: 221 QPSSRSM---IWDSMFCAGAEDGSVDTCKGDSGGPLVC-DKDGLWYQVGIVSWGMDCGQP 276
Query: 253 DAPVLLTNTAAHSSWLQ 269
+ P + TN + + W++
Sbjct: 277 NRPGVYTNISVYFHWIR 293
Score = 117 bits (294), Expect = 2e-26
Identities = 82/249 (32%), Positives = 115/249 (46%), Gaps = 23/249 (9%)
Query: 295 ACGSLR----TAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAPE 350
ACG AG A WPW+A L + + CGG+L+S VL+AAHCF P
Sbjct: 45 ACGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPS 104
Query: 351 EWSVGLG---TRPEEWGLK----QLILHGAYTHPEG----GYDMALLLLAQPVTLGASLR 399
EW+V LG +RP W L+ + + +P+ D+ALL LA VT A ++
Sbjct: 105 EWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYNAYIQ 164
Query: 400 PLCLPYPDHHLPDGERGWVLG------RARPGAGISSLQTVPVTLLGPRACSRLHAAPGG 453
P+C+ + WV G P +L+ VT+L C+ L P
Sbjct: 165 PICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQP-S 223
Query: 454 DGSPILPGMVCTSAV-GELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFT 512
S I M C A G + +C+G SG PLV + G W+ G+ S+G C P RP V+T
Sbjct: 224 SRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYT 283
Query: 513 ALPAYEDWV 521
+ Y W+
Sbjct: 284 NISVYFHWI 292
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 133 bits (334), Expect = 5e-31
Identities = 89/262 (33%), Positives = 120/262 (45%), Gaps = 21/262 (8%)
Query: 21 LQAAQRACGQRGPGPPKPQEG-NTVPGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCF 79
L A + CG+R + G +T G WPWQ S+R GAH+C GSL++ WVLTAAHCF
Sbjct: 146 LAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCF 205
Query: 80 EKAAATELNSWSVVLGSLQR---EGLSPGAEEVGVAALQLP-RAYNHYSQGSDLALLQLA 135
+ L+ W V G++ + GL G + V LP R N +D+AL+ L+
Sbjct: 206 PERNRV-LSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLS 264
Query: 136 HPTTHT----PLCLPQPAHRFPFGASCWATGW--DQDTSDAPGTLRNLRLRLISRPTCNC 189
P T P+CLP G C TGW Q G L+ R+ +IS CN
Sbjct: 265 SPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCN- 323
Query: 190 IYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLC---LEPDGHWVQAGIISFA 246
N +P M C G G CQGDSGGP +C + W GI+S+
Sbjct: 324 -----GADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG 378
Query: 247 SSCAQEDAPVLLTNTAAHSSWL 268
+ CA P + T + W+
Sbjct: 379 TGCALAQKPGVYTKVSDFREWI 400
Score = 102 bits (254), Expect = 9e-22
Identities = 78/257 (30%), Positives = 116/257 (45%), Gaps = 34/257 (13%)
Query: 293 CVACGSL-----RTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGR- 346
C CG R G + + WPW+ L + G CGG+L+S + VLTAAHCF R
Sbjct: 150 CQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERN 209
Query: 347 QAPEEWSVGLGTRPE------EWGLKQLILHGAY------THPEGGYDMALLLLAQPVTL 394
+ W V G + + G++ ++ HG Y E D+AL+ L+ P+ L
Sbjct: 210 RVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPL 269
Query: 395 GASLRPLCLPYPDHHLPDGERGWVLGRARP---GAGISSLQTVPVTLLGPRACSRLHAAP 451
++P+CLP L DG+ V G G LQ V ++ C+
Sbjct: 270 TEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCN------ 323
Query: 452 GGD--GSPILPGMVCTS-AVGELPSCEGLSGAPLVHE--VRGT--WFLAGLHSFGDACQG 504
G D G+ I P M C G + +C+G SG P V E + T W L G+ S+G C
Sbjct: 324 GADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCAL 383
Query: 505 PARPAVFTALPAYEDWV 521
+P V+T + + +W+
Sbjct: 384 AQKPGVYTKVSDFREWI 400
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 133 bits (334), Expect = 5e-31
Identities = 89/262 (33%), Positives = 120/262 (45%), Gaps = 21/262 (8%)
Query: 21 LQAAQRACGQRGPGPPKPQEG-NTVPGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCF 79
L A + CG+R + G +T G WPWQ S+R GAH+C GSL++ WVLTAAHCF
Sbjct: 146 LAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCF 205
Query: 80 EKAAATELNSWSVVLGSLQR---EGLSPGAEEVGVAALQLP-RAYNHYSQGSDLALLQLA 135
+ L+ W V G++ + GL G + V LP R N +D+AL+ L+
Sbjct: 206 PERNRV-LSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLS 264
Query: 136 HPTTHT----PLCLPQPAHRFPFGASCWATGW--DQDTSDAPGTLRNLRLRLISRPTCNC 189
P T P+CLP G C TGW Q G L+ R+ +IS CN
Sbjct: 265 SPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCN- 323
Query: 190 IYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLC---LEPDGHWVQAGIISFA 246
N +P M C G G CQGDSGGP +C + W GI+S+
Sbjct: 324 -----GADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG 378
Query: 247 SSCAQEDAPVLLTNTAAHSSWL 268
+ CA P + T + W+
Sbjct: 379 TGCALAQKPGVYTKVSDFREWI 400
Score = 102 bits (254), Expect = 9e-22
Identities = 78/257 (30%), Positives = 116/257 (45%), Gaps = 34/257 (13%)
Query: 293 CVACGSL-----RTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGR- 346
C CG R G + + WPW+ L + G CGG+L+S + VLTAAHCF R
Sbjct: 150 CQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERN 209
Query: 347 QAPEEWSVGLGTRPE------EWGLKQLILHGAY------THPEGGYDMALLLLAQPVTL 394
+ W V G + + G++ ++ HG Y E D+AL+ L+ P+ L
Sbjct: 210 RVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPL 269
Query: 395 GASLRPLCLPYPDHHLPDGERGWVLGRARP---GAGISSLQTVPVTLLGPRACSRLHAAP 451
++P+CLP L DG+ V G G LQ V ++ C+
Sbjct: 270 TEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCN------ 323
Query: 452 GGD--GSPILPGMVCTS-AVGELPSCEGLSGAPLVHE--VRGT--WFLAGLHSFGDACQG 504
G D G+ I P M C G + +C+G SG P V E + T W L G+ S+G C
Sbjct: 324 GADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCAL 383
Query: 505 PARPAVFTALPAYEDWV 521
+P V+T + + +W+
Sbjct: 384 AQKPGVYTKVSDFREWI 400
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 133 bits (334), Expect = 5e-31
Identities = 90/259 (34%), Positives = 119/259 (45%), Gaps = 27/259 (10%)
Query: 28 CGQRGPGPPKPQEGNTV-PGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAATE 86
CG R P + G +V PG WPWQASV H C GS++A WV+TAAHC
Sbjct: 209 CGAR-PLASRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLAR 267
Query: 87 LNSWSVVLGSLQREGLSP--GAEEVGVAALQLPRAYNHYSQGSDLALLQLA----HPTTH 140
L+SW V G + + P GA + L A NH D+ALL+L T
Sbjct: 268 LSSWRVHAGLVSHSAVRPHQGALVERIIPHPLYSAQNH---DYDVALLRLQTALNFSDTV 324
Query: 141 TPLCLPQPAHRFPFGASCWATGWDQ---DTSDAPGTLRNLRLRLISRPTCN--CIYNQLH 195
+CLP FP G+ CW +GW + + L++ + L S CN C+Y
Sbjct: 325 GAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVY---- 380
Query: 196 QRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGH-WVQAGIISFASSCAQEDA 254
S P MLC G G CQGDSGGP++C PDG W G++S+ CA+ +
Sbjct: 381 ----SGALTPRMLCAGYLDGRADACQGDSGGPLVC--PDGDTWRLVGVVSWGRGCAEPNH 434
Query: 255 PVLLTNTAAHSSWLQARVQ 273
P + A W+ Q
Sbjct: 435 PGVYAKVAEFLDWIHDTAQ 453
Score = 115 bits (287), Expect = 1e-25
Identities = 78/247 (31%), Positives = 113/247 (45%), Gaps = 22/247 (8%)
Query: 293 CVACGSL----RTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQA 348
C CG+ R G Q+ AP WPW+A + + CGG++++ V+TAAHC +
Sbjct: 206 CSECGARPLASRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRL 265
Query: 349 PE--EWSVGLG------TRPEEWGL-KQLILHGAYTHPEGGYDMALLLLAQPVTLGASLR 399
W V G RP + L +++I H Y+ YD+ALL L + ++
Sbjct: 266 ARLSSWRVHAGLVSHSAVRPHQGALVERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVG 325
Query: 400 PLCLPYPDHHLPDGERGWVLG--RARPGAGISS--LQTVPVTLLGPRACSRLHAAPGGDG 455
+CLP + H P G R WV G P SS LQ V L + C+ G
Sbjct: 326 AVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVYSGA-- 383
Query: 456 SPILPGMVCTSAV-GELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTAL 514
+ P M+C + G +C+G SG PLV TW L G+ S+G C P P V+ +
Sbjct: 384 --LTPRMLCAGYLDGRADACQGDSGGPLVCPDGDTWRLVGVVSWGRGCAEPNHPGVYAKV 441
Query: 515 PAYEDWV 521
+ DW+
Sbjct: 442 AEFLDWI 448
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 132 bits (333), Expect = 6e-31
Identities = 79/231 (34%), Positives = 115/231 (49%), Gaps = 21/231 (9%)
Query: 45 PGEWPWQASVR-RQGAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLS 103
P WPWQ S+R R G H C G+L++ WVLTAAHC EK+ +S+ V+LG+ Q L
Sbjct: 589 PHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRP--SSYKVILGAHQEVNLE 646
Query: 104 PGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHT----PLCLPQPAHRFPFGASCW 159
P +E+ V+ L L D+ALL+L+ P T P CLP P + C+
Sbjct: 647 PHVQEIEVSRLFLE------PTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECF 700
Query: 160 ATGWDQDTSD-APGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQG 218
TGW + G L+ +L +I CN L+ + LC G G
Sbjct: 701 ITGWGETQGTFGAGLLKEAQLPVIENKVCN------RYEFLNGRVQSTELCAGHLAGGTD 754
Query: 219 PCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQ 269
CQGDSGGP++C E D + +Q G+ S+ CA+ + P + + +W++
Sbjct: 755 SCQGDSGGPLVCFEKDKYILQ-GVTSWGLGCARPNKPGVYVRVSRFVTWIE 804
Score = 96.3 bits (238), Expect = 7e-20
Identities = 71/234 (30%), Positives = 106/234 (45%), Gaps = 16/234 (6%)
Query: 300 RTAGPQAGAPSPWPWEARLMHQ-GQLACGGALVSEEAVLTAAHCFIGRQAPEEWSVGLGT 358
R G P WPW+ L + G CGG L+S E VLTAAHC P + V LG
Sbjct: 580 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGA 639
Query: 359 RPE---EWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGER 415
E E ++++ + + P D+ALL L+ P + + P CLP P++ + D
Sbjct: 640 HQEVNLEPHVQEIEVSRLFLEPTRK-DIALLKLSSPAVITDKVIPACLPSPNYVVADRTE 698
Query: 416 ----GWVLGRARPGAGISSLQTVPVTLLGPRACSRLHAAPGGDGSPILPGMVCTSAV-GE 470
GW + GAG+ +PV + + C+R G S L C + G
Sbjct: 699 CFITGWGETQGTFGAGLLKEAQLPV--IENKVCNRYEFLNGRVQSTEL----CAGHLAGG 752
Query: 471 LPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSSL 524
SC+G SG PLV + + L G+ S+G C P +P V+ + + W+ +
Sbjct: 753 TDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGV 806
>gi|5803197 testisin isoform 1 [Homo sapiens]
Length = 314
Score = 130 bits (328), Expect = 2e-30
Identities = 78/253 (30%), Positives = 121/253 (47%), Gaps = 18/253 (7%)
Query: 46 GEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEK-AAATELNSWSVVLGSLQRE---- 100
G WPWQ S+R +H+C SL++ W LTAAHCFE + ++ + W V G L
Sbjct: 51 GRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFW 110
Query: 101 GLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHT----PLCLPQPAHRFPFGA 156
L V+ + L Y S D+AL++L+ P T+T P+CL F
Sbjct: 111 SLQAYYTRYFVSNIYLSPRYLGNSP-YDIALVKLSAPVTYTKHIQPICLQASTFEFENRT 169
Query: 157 SCWATGW----DQDTSDAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGP 212
CW TGW + + +P TL+ +++ +I+ CN ++ + R M+C G
Sbjct: 170 DCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFR---KDIFGDMVCAGN 226
Query: 213 QPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQARV 272
G + C GDSGGP+ C +G W Q G++S+ C + + P + TN + H W+Q +
Sbjct: 227 AQGGKDACFGDSGGPLAC-NKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLM 285
Query: 273 QGAAFLAQSPETP 285
+ P P
Sbjct: 286 AQSGMSQPDPSWP 298
Score = 95.5 bits (236), Expect = 1e-19
Identities = 76/259 (29%), Positives = 108/259 (41%), Gaps = 26/259 (10%)
Query: 300 RTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCF---IGRQAPEEWSVGL 356
R G + WPW+ L CG +L+S LTAAHCF P W V
Sbjct: 41 RIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQF 100
Query: 357 G---TRPEEWGLK----QLILHGAYTHPE----GGYDMALLLLAQPVTLGASLRPLCLPY 405
G + P W L+ + + Y P YD+AL+ L+ PVT ++P+CL
Sbjct: 101 GQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQA 160
Query: 406 PDHHLPDGERGWVLG-------RARPGAGISSLQTVPVTLLGPRACSRLHAAPGGDGSPI 458
+ WV G A P +LQ V V ++ C+ L I
Sbjct: 161 STFEFENRTDCWVTGWGYIKEDEALPSP--HTLQEVQVAIINNSMCNHLFLKYSFR-KDI 217
Query: 459 LPGMVCT-SAVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAY 517
MVC +A G +C G SG PL G W+ G+ S+G C P RP V+T + +
Sbjct: 218 FGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHH 277
Query: 518 EDWVSSLDWQVYFAEEPEP 536
+W+ L Q + +P+P
Sbjct: 278 FEWIQKLMAQSGMS-QPDP 295
>gi|21614531 testisin isoform 2 [Homo sapiens]
Length = 312
Score = 130 bits (328), Expect = 2e-30
Identities = 78/252 (30%), Positives = 120/252 (47%), Gaps = 18/252 (7%)
Query: 46 GEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQRE----G 101
G WPWQ S+R +H+C SL++ W LTAAHCFE ++ + W V G L
Sbjct: 51 GRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFE-TDLSDPSGWMVQFGQLTSMPSFWS 109
Query: 102 LSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHT----PLCLPQPAHRFPFGAS 157
L V+ + L Y S D+AL++L+ P T+T P+CL F
Sbjct: 110 LQAYYTRYFVSNIYLSPRYLGNSP-YDIALVKLSAPVTYTKHIQPICLQASTFEFENRTD 168
Query: 158 CWATGW----DQDTSDAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQ 213
CW TGW + + +P TL+ +++ +I+ CN ++ + R M+C G
Sbjct: 169 CWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFR---KDIFGDMVCAGNA 225
Query: 214 PGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQARVQ 273
G + C GDSGGP+ C +G W Q G++S+ C + + P + TN + H W+Q +
Sbjct: 226 QGGKDACFGDSGGPLAC-NKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMA 284
Query: 274 GAAFLAQSPETP 285
+ P P
Sbjct: 285 QSGMSQPDPSWP 296
Score = 96.7 bits (239), Expect = 5e-20
Identities = 76/257 (29%), Positives = 108/257 (42%), Gaps = 24/257 (9%)
Query: 300 RTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCF-IGRQAPEEWSVGLG- 357
R G + WPW+ L CG +L+S LTAAHCF P W V G
Sbjct: 41 RIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETDLSDPSGWMVQFGQ 100
Query: 358 --TRPEEWGLK----QLILHGAYTHPE----GGYDMALLLLAQPVTLGASLRPLCLPYPD 407
+ P W L+ + + Y P YD+AL+ L+ PVT ++P+CL
Sbjct: 101 LTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQAST 160
Query: 408 HHLPDGERGWVLG-------RARPGAGISSLQTVPVTLLGPRACSRLHAAPGGDGSPILP 460
+ WV G A P +LQ V V ++ C+ L I
Sbjct: 161 FEFENRTDCWVTGWGYIKEDEALPSP--HTLQEVQVAIINNSMCNHLFLKYSFR-KDIFG 217
Query: 461 GMVCT-SAVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYED 519
MVC +A G +C G SG PL G W+ G+ S+G C P RP V+T + + +
Sbjct: 218 DMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFE 277
Query: 520 WVSSLDWQVYFAEEPEP 536
W+ L Q + +P+P
Sbjct: 278 WIQKLMAQSGMS-QPDP 293
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 130 bits (326), Expect = 4e-30
Identities = 75/234 (32%), Positives = 114/234 (48%), Gaps = 17/234 (7%)
Query: 47 EWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSPGA 106
+WPWQ S+ HIC G+L+ WVLTAAHCF L W V G+ L
Sbjct: 336 KWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGT---SNLHQLP 392
Query: 107 EEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHT----PLCLPQPAHRFPFGASCWATG 162
E +A + + Y D+AL++L+ P T + P CLP F +CW TG
Sbjct: 393 EAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITG 452
Query: 163 W--DQDTSDAPGT-LRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGP 219
+ ++T D LR +++ LI CN ++ +L+ P M+C G G +
Sbjct: 453 FGKTRETDDKTSPFLREVQVNLIDFKKCNDYL--VYDSYLT----PRMMCAGDLRGGRDS 506
Query: 220 CQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQARVQ 273
CQGDSGGP++C E + W AG+ S+ + C Q + P + T W+ ++++
Sbjct: 507 CQGDSGGPLVC-EQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKME 559
Score = 122 bits (307), Expect = 7e-28
Identities = 83/255 (32%), Positives = 119/255 (46%), Gaps = 21/255 (8%)
Query: 293 CVACG----SLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFI--GR 346
C CG + R G + S WPW+ L CGG L+ + VLTAAHCF
Sbjct: 314 CSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTRE 373
Query: 347 QAPEEWSVGLGTR-----PEEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPL 401
+ E W V GT PE + ++I++ YT E YD+AL+ L++P+TL A + P
Sbjct: 374 KVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPA 433
Query: 402 CLPYPDHHLPDGERGWVLG----RARPGAGISSLQTVPVTLLGPRACSRLHAAPGGDGSP 457
CLP E W+ G R L+ V V L+ + C+ S
Sbjct: 434 CLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVY----DSY 489
Query: 458 ILPGMVCTSAV-GELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPA 516
+ P M+C + G SC+G SG PLV E W+LAG+ S+G C +P V+T +
Sbjct: 490 LTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTE 549
Query: 517 YEDWV-SSLDWQVYF 530
W+ S ++ +V F
Sbjct: 550 VLPWIYSKMESEVRF 564
>gi|110815798 ovochymase 1 [Homo sapiens]
Length = 1134
Score = 129 bits (325), Expect = 5e-30
Identities = 86/305 (28%), Positives = 135/305 (44%), Gaps = 29/305 (9%)
Query: 45 PGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSP 104
P WPWQ +R G + C G+++ W+LTAAHC + SW+++ G R L
Sbjct: 583 PHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQ--LKNNPLSWTIIAGDHDRN-LKE 639
Query: 105 GAEEVGVAA-LQLPRAYNHYSQGSDLALLQLAHPTTHT----PLCLPQPAHRFPFGASCW 159
E+V A + + +N S SD+AL+QL+ P + P+CLP A C
Sbjct: 640 STEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHSAEPLFSSEICA 699
Query: 160 ATGWDQDTSDA--PGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGG-PQPGV 216
TGW ++D L+ +++ ++ R C Y H ++ M+C G G
Sbjct: 700 VTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEK----MICAGFAASGE 755
Query: 217 QGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQARVQGAA 276
+ CQGDSGGP++C +G +V GI+S+ + C Q P + W+Q+++ G A
Sbjct: 756 KDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLDWIQSKINGPA 815
Query: 277 FLAQS-----------PETPEMSDEDSCVACGSLRTAGPQAGAPSPWPWEARLMHQGQLA 325
L + P TP C P+ P+P L ++G+L
Sbjct: 816 SLQTNNKCKTLKQQLPPPTPSPDSASWPGCCSEAELEKPRGFFPTP---RYLLDYRGRLE 872
Query: 326 CGGAL 330
C L
Sbjct: 873 CSWVL 877
Score = 113 bits (283), Expect = 4e-25
Identities = 80/245 (32%), Positives = 117/245 (47%), Gaps = 26/245 (10%)
Query: 298 SLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAPEEWSVGLG 357
S R AG + P WPW+ L G CGGA+++ +LTAAHC + P W++ G
Sbjct: 572 SRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAG 631
Query: 358 --------TRPEEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHH 409
+ + K +I+H + D+AL+ L+ P+ + +RP+CLP+
Sbjct: 632 DHDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHSAEP 691
Query: 410 LPDGE----RGWVLGRARPGAGISS-LQTVPVTLLGPRACSRLH--AAPGGDGSPILPGM 462
L E GW G G++S LQ + V +L C + A PGG I M
Sbjct: 692 LFSSEICAVTGW--GSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGG----ITEKM 745
Query: 463 VCT--SAVGELPSCEGLSGAPLV--HEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYE 518
+C +A GE C+G SG PLV HE G + L G+ S+G C P +P VF + +
Sbjct: 746 ICAGFAASGEKDFCQGDSGGPLVCRHE-NGPFVLYGIVSWGAGCVQPWKPGVFARVMIFL 804
Query: 519 DWVSS 523
DW+ S
Sbjct: 805 DWIQS 809
Score = 112 bits (281), Expect = 7e-25
Identities = 73/248 (29%), Positives = 112/248 (45%), Gaps = 12/248 (4%)
Query: 16 VLMEGLQAAQRACGQRGPGPPKPQEGNTVPGEWPWQASVRRQGAHICSGSLVADTWVLTA 75
+ M +++ + A G R +TV G PWQ S++ H C GSL+ + V+TA
Sbjct: 27 IRMVNMKSKEPAVGSRFFSRISSWRNSTVTGH-PWQVSLKSDEHHFCGGSLIQEDRVVTA 85
Query: 76 AHCFEKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGS-DLALLQL 134
AHC + + +L + +V G + + V+ + YN S D+ALL L
Sbjct: 86 AHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYL 145
Query: 135 AHPTTH----TPLCLPQPAHRFPFGASCWATGWDQ--DTSDAPGTLRNLRLRLISRPTCN 188
H P+CLP + G C ++GW + TS+ L+ + L ++ CN
Sbjct: 146 KHKVKFGNAVQPICLPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACN 205
Query: 189 CIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASS 248
+ ++ L MLC G CQGDSGGP++C G W+ AGI S+ +
Sbjct: 206 TVLKSMNLPPLGRT----MLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVAG 261
Query: 249 CAQEDAPV 256
CA PV
Sbjct: 262 CAGGSVPV 269
Score = 72.8 bits (177), Expect = 8e-13
Identities = 62/214 (28%), Positives = 99/214 (46%), Gaps = 22/214 (10%)
Query: 313 PWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAPE---------EWSVGLGTRPEE- 362
PW+ L CGG+L+ E+ V+TAAHC + E+S+ + E+
Sbjct: 59 PWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQN 118
Query: 363 WGLKQLILHGAYTHPE-GGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDG----ERGW 417
+ ++I H Y E D+ALL L V G +++P+CLP D + G GW
Sbjct: 119 IPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGW 178
Query: 418 VLGRARPGAGISS-LQTVPVTLLGPRACSRLHAAPGGDGSPILPGMVCTSAVG-ELPSCE 475
G+ + S+ LQ + + ++ RAC+ + + P+ M+C + +C+
Sbjct: 179 --GKISKTSEYSNVLQEMELPIMDDRACNTV--LKSMNLPPLGRTMLCAGFPDWGMDACQ 234
Query: 476 GLSGAPLV-HEVRGTWFLAGLHSFGDACQGPARP 508
G SG PLV G W LAG+ S+ C G + P
Sbjct: 235 GDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVP 268
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 127 bits (320), Expect = 2e-29
Identities = 71/248 (28%), Positives = 119/248 (47%), Gaps = 19/248 (7%)
Query: 42 NTVPGEWPWQASVRRQ---GAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQ 98
N+ GEWPWQ S++ + H+C GSL+ WVLTAAHCF+ ++ W + G L
Sbjct: 396 NSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDV--WRIYSGILN 453
Query: 99 REGLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHT----PLCLPQPAHRFPF 154
++ + + + + Y D+AL++L P +T P+CLP
Sbjct: 454 LSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTI 513
Query: 155 GASCWATGW--DQDTSDAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGP 212
+CW TGW ++ + L+ + + L++ C +R+ M+C G
Sbjct: 514 YTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEC-------QKRYQDYKITQRMVCAGY 566
Query: 213 QPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQARV 272
+ G + C+GDSGGP++C + +G W GI S+ CA+ + P + T A + W+ +
Sbjct: 567 KEGGKDACKGDSGGPLVC-KHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKT 625
Query: 273 QGAAFLAQ 280
Q + AQ
Sbjct: 626 QSSDGKAQ 633
Score = 108 bits (271), Expect = 1e-23
Identities = 74/248 (29%), Positives = 110/248 (44%), Gaps = 20/248 (8%)
Query: 289 DEDSCVACGSLRTAGPQAGAPSPWPWEARL---MHQGQLACGGALVSEEAVLTAAHCFIG 345
D C S R G + WPW+ L + + CGG+L+ + VLTAAHCF G
Sbjct: 379 DNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDG 438
Query: 346 RQAPEEWSVGLG-------TRPEEWG-LKQLILHGAYTHPEGGYDMALLLLAQPVTLGAS 397
+ W + G T+ + +K++I+H Y EG +D+AL+ L P+
Sbjct: 439 LPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEF 498
Query: 398 LRPLCLPYPDHHLPDGERGWVLG---RARPGAGISSLQTVPVTLLGPRACSRLHAAPGGD 454
+P+CLP WV G G + LQ V + L+ C + +
Sbjct: 499 QKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRY-----Q 553
Query: 455 GSPILPGMVCTS-AVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTA 513
I MVC G +C+G SG PLV + G W L G+ S+G+ C +P V+T
Sbjct: 554 DYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTK 613
Query: 514 LPAYEDWV 521
+ Y DW+
Sbjct: 614 VAEYMDWI 621
>gi|110578663 hypothetical protein LOC203074 [Homo sapiens]
Length = 352
Score = 125 bits (314), Expect = 1e-28
Identities = 100/338 (29%), Positives = 149/338 (44%), Gaps = 58/338 (17%)
Query: 20 GLQAAQRACGQRGPGPPKPQ------------EGNT-----------VPGEWPWQASVRR 56
G+ RA G P PP P EG T GE+PWQ S++
Sbjct: 28 GVAILGRARGAHRPQPPHPPSPVSECGDRSIFEGRTRYSRITGGMEAEVGEFPWQVSIQA 87
Query: 57 QGAHICSGSLVADTWVLTAAHCF--EKAAATELNSWSVVLGSLQREGLSPGAEEVGVAAL 114
+ C GS++ W+LTAAHC E+ EL SVVLG+ + SP E VA++
Sbjct: 88 RSEPFCGGSILNKWWILTAAHCLYSEELFPEEL---SVVLGT--NDLTSPSMEIKEVASI 142
Query: 115 QLPRAYNHYSQGSDLALLQLAHP----TTHTPLCLP-QPAHRFPFGASCWATGWDQ---- 165
L + + + +D+ALL LA P P+CLP QP CW GW Q
Sbjct: 143 ILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGP--ATWRECWVAGWGQTNAA 200
Query: 166 DTSDAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSG 225
D + L + ++ C+ ++ +L + MLC G + C+GDSG
Sbjct: 201 DKNSVKTDLMKAPMVIMDWEECSKMFPKLTK---------NMLCAGYKNESYDACKGDSG 251
Query: 226 GPVLCL-EPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQ--ARVQGAAFLAQSP 282
GP++C EP W Q GIIS+ SC +++ P + T+ ++ W++ +++G F A+
Sbjct: 252 GPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKVTQLEGRPFNAEKR 311
Query: 283 ETPEMSDEDSCVACGSLRTAGPQAGAPSPWPWEARLMH 320
T GS + P+ G+P W L H
Sbjct: 312 RTSVKQK-----PMGSPVSGVPEPGSPRSWLLLCPLSH 344
Score = 92.8 bits (229), Expect = 7e-19
Identities = 76/274 (27%), Positives = 122/274 (44%), Gaps = 29/274 (10%)
Query: 300 RTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQA-PEEWSVGLGT 358
R G +PW+ + + + CGG+++++ +LTAAHC + PEE SV LGT
Sbjct: 67 RITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGT 126
Query: 359 RP------EEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPD 412
E + +ILH + D+ALLLLA P+ L P+CLP
Sbjct: 127 NDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGPATW 186
Query: 413 GERGWVLGRARPGAG-----ISSLQTVPVTLLGPRACSRLHAAPGGDGSPILPGMVCTSA 467
E WV G + A + L P+ ++ CS++ + M+C
Sbjct: 187 RE-CWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMF-------PKLTKNMLCAGY 238
Query: 468 VGE-LPSCEGLSGAPLV--HEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDW---V 521
E +C+G SG PLV E W+ G+ S+G +C P ++T+L Y W V
Sbjct: 239 KNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKV 298
Query: 522 SSLDWQVYFAEEPEPEAEP---GSCLANISQPTS 552
+ L+ + + AE+ + GS ++ + +P S
Sbjct: 299 TQLEGRPFNAEKRRTSVKQKPMGSPVSGVPEPGS 332
>gi|34098976 marapsin 2 [Homo sapiens]
Length = 326
Score = 125 bits (313), Expect = 1e-28
Identities = 82/244 (33%), Positives = 121/244 (49%), Gaps = 27/244 (11%)
Query: 34 GPPKPQEGNTVPGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVV 93
G P P+ +WPWQ SV G H+C GS++ + WVL+AAHCF + ++ V
Sbjct: 63 GVPAPER------KWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVG 116
Query: 94 LGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQL----AHPTTHTPLCLPQPA 149
L +L+ G EV L P ++ G D+AL+QL + P+CL P
Sbjct: 117 LVNLRVAGNHTQWYEVNRVILH-PTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPE 175
Query: 150 HRFPFGASCWATGW-----DQDTSDAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPAR 204
A+CWATGW +TSD L+ ++L LI P C+ +Y H+S
Sbjct: 176 VNLT-SANCWATGWGLVSKQGETSD---ELQEMQLPLILEPWCHLLYG-----HMSY-IM 225
Query: 205 PGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAH 264
P MLC G + C+GDSGGP++C E + W+Q GI+S+ C+ P + + +
Sbjct: 226 PDMLCAGDILNAKTVCEGDSGGPLVC-EFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYF 284
Query: 265 SSWL 268
S W+
Sbjct: 285 SKWI 288
Score = 110 bits (276), Expect = 3e-24
Identities = 84/265 (31%), Positives = 129/265 (48%), Gaps = 25/265 (9%)
Query: 275 AAFLAQSPETPEMSDEDSCVACGSLRTAGP-QAGAPSP---WPWEARLMHQGQLACGGAL 330
AA + + PE +S S VACG G G P+P WPW+ + + G CGG++
Sbjct: 31 AALVHRQPENQGISLTGS-VACGRPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGGSI 89
Query: 331 VSEEAVLTAAHCFIGRQAPEEWS--VGL------GTRPEEWGLKQLILHGAYT--HPEGG 380
++E VL+AAHCF + + + VGL G + + + ++ILH Y HP GG
Sbjct: 90 LNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMYHPIGG 149
Query: 381 YDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGE---RGWVLGRARPGAGISSLQTVPVT 437
D+AL+ L + S+ P+CL P+ +L GW L ++ G LQ + +
Sbjct: 150 -DVALVQLKTRIVFSESVLPVCLATPEVNLTSANCWATGWGLV-SKQGETSDELQEMQLP 207
Query: 438 LLGPRACSRLHAAPGGDGSPILPGMVCTSAVGELPS-CEGLSGAPLVHEVRGTWFLAGLH 496
L+ C L+ G S I+P M+C + + CEG SG PLV E +W G+
Sbjct: 208 LILEPWCHLLY----GHMSYIMPDMLCAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIV 263
Query: 497 SFGDACQGPARPAVFTALPAYEDWV 521
S+G C P P V+ ++ + W+
Sbjct: 264 SWGRGCSNPLYPGVYASVSYFSKWI 288
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 124 bits (311), Expect = 2e-28
Identities = 71/240 (29%), Positives = 112/240 (46%), Gaps = 19/240 (7%)
Query: 43 TVPGEWPWQASVRRQGA---HICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQR 99
+V GEWPWQ ++ H+C GS++ + W+LTAAHCF + ++ V G L +
Sbjct: 394 SVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKI--LRVYSGILNQ 451
Query: 100 EGLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHT----PLCLPQPAHRFPFG 155
+ GV + + Y G D+ALL+L +T P+CLP R
Sbjct: 452 SEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIY 511
Query: 156 ASCWATGWD--QDTSDAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQ 213
CW TGW + TL+ ++ L++ C +R+ + M+C G +
Sbjct: 512 TDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEEC-------QKRYRGHKITHKMICAGYR 564
Query: 214 PGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQARVQ 273
G + C+GDSGGP+ C + + W GI S+ CAQ + P + TN + W+ + Q
Sbjct: 565 EGGKDACKGDSGGPLSC-KHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQ 623
Score = 109 bits (272), Expect = 7e-24
Identities = 73/247 (29%), Positives = 109/247 (44%), Gaps = 20/247 (8%)
Query: 290 EDSCVACGSLRTAGPQAGAPSPWPWEARLMHQGQLA---CGGALVSEEAVLTAAHCFIGR 346
++ C R G A WPW+ L CGG+++ + +LTAAHCF G
Sbjct: 377 DNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGV 436
Query: 347 QAPEEWSVGLGTRPEE--------WGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASL 398
++P+ V G + +G++++I+H Y E GYD+ALL L V S
Sbjct: 437 ESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQ 496
Query: 399 RPLCLPYPDHHLPDGERGWVLG---RARPGAGISSLQTVPVTLLGPRACSRLHAAPGGDG 455
RP+CLP WV G R ++LQ + L+ C + + G
Sbjct: 497 RPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYR-----G 551
Query: 456 SPILPGMVCTS-AVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTAL 514
I M+C G +C+G SG PL + W L G+ S+G+ C RP V+T +
Sbjct: 552 HKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNV 611
Query: 515 PAYEDWV 521
Y DW+
Sbjct: 612 VEYVDWI 618
>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
Length = 2040
Score = 124 bits (310), Expect = 3e-28
Identities = 75/235 (31%), Positives = 116/235 (49%), Gaps = 30/235 (12%)
Query: 45 PGEWPWQASVR-RQGAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLS 103
P WPWQ S+R R G H C G+L++ WVLTAAHC +K++ +S+ V+LG+ Q L
Sbjct: 1828 PHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLKKSSRP--SSYKVILGAHQEVNLE 1885
Query: 104 PGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHT----PLCLPQPAHRFPFGASCW 159
+E+ V+ L L +D+ALL+L+ P T P CLP P + C+
Sbjct: 1886 SHVQEIEVSRLFLEPTQ------ADIALLKLSRPAVITDKVMPACLPSPDYMVTARTECY 1939
Query: 160 ATGWDQDTSD-APGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQG 218
TGW + G L+ +L +I CN Y + HL+
Sbjct: 1940 ITGWGETQGTFGTGLLKEAQLLVIENEVCN-HYKYICAEHLARGT--------------D 1984
Query: 219 PCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQARVQ 273
CQGDSGGP++C E D + +Q G+ S+ CA+ + P + + +W++ ++
Sbjct: 1985 SCQGDSGGPLVCFEKDKYILQ-GVTSWGLGCARPNKPGVYARVSRFVTWIEGMMR 2038
Score = 90.5 bits (223), Expect = 4e-18
Identities = 65/230 (28%), Positives = 100/230 (43%), Gaps = 35/230 (15%)
Query: 309 PSPWPWEARLMHQ-GQLACGGALVSEEAVLTAAHCFIGRQAPEEWSVGLGTRPE---EWG 364
P WPW+ L + G+ CGG L+S E VLTAAHC P + V LG E E
Sbjct: 1828 PHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAHQEVNLESH 1887
Query: 365 LKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGER----GWVLG 420
++++ + + P D+ALL L++P + + P CLP PD+ + GW G
Sbjct: 1888 VQEIEVSRLFLEPTQA-DIALLKLSRPAVITDKVMPACLPSPDYMVTARTECYITGW--G 1944
Query: 421 RARPGAGISSLQTVPVTLLGPRACSRL------HAAPGGDGSPILPGMVCTSAVGELPSC 474
+ G L+ + ++ C+ H A G D SC
Sbjct: 1945 ETQGTFGTGLLKEAQLLVIENEVCNHYKYICAEHLARGTD------------------SC 1986
Query: 475 EGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSSL 524
+G SG PLV + + L G+ S+G C P +P V+ + + W+ +
Sbjct: 1987 QGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEGM 2036
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 122 bits (307), Expect = 7e-28
Identities = 75/241 (31%), Positives = 109/241 (45%), Gaps = 17/241 (7%)
Query: 42 NTVPGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREG 101
+ +PG WPWQ S+ Q H+C GS++ W++TAAHC EK + W+ G L++
Sbjct: 298 SALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWH-WTAFAGILRQSF 356
Query: 102 LSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHT----PLCLPQPAHRFPFGAS 157
+ GA + P Y+ ++ +D+AL++L P T P+CLP P
Sbjct: 357 MFYGAGYQVEKVISHPN-YDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQL 415
Query: 158 CWATGW--DQDTSDAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPG 215
CW +GW ++ L ++ LI CN Y N P M+C G G
Sbjct: 416 CWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRY------VYDNLITPAMICAGFLQG 469
Query: 216 VQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWL--QARVQ 273
CQGDSGGP L + W G S+ S CA+ P + N + W+ Q R
Sbjct: 470 NVDSCQGDSGGP-LVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRAD 528
Query: 274 G 274
G
Sbjct: 529 G 529
Score = 112 bits (279), Expect = 1e-24
Identities = 70/248 (28%), Positives = 111/248 (44%), Gaps = 23/248 (9%)
Query: 293 CVACG-------SLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCF-I 344
C+ACG R G ++ P WPW+ L Q CGG++++ E ++TAAHC
Sbjct: 278 CIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEK 337
Query: 345 GRQAPEEWSVGLGTRPEE-------WGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGAS 397
P W+ G + + ++++I H Y D+AL+ L +P+T
Sbjct: 338 PLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDL 397
Query: 398 LRPLCLPYPDHHLPDGERGWVLG---RARPGAGISSLQTVPVTLLGPRACSRLHAAPGGD 454
++P+CLP P L + W+ G G L V L+ + C+ +
Sbjct: 398 VKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVY---- 453
Query: 455 GSPILPGMVCTSAV-GELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTA 513
+ I P M+C + G + SC+G SG PLV W+L G S+G C RP V+
Sbjct: 454 DNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGN 513
Query: 514 LPAYEDWV 521
+ + DW+
Sbjct: 514 VMVFTDWI 521
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 122 bits (307), Expect = 7e-28
Identities = 75/241 (31%), Positives = 109/241 (45%), Gaps = 17/241 (7%)
Query: 42 NTVPGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREG 101
+ +PG WPWQ S+ Q H+C GS++ W++TAAHC EK + W+ G L++
Sbjct: 261 SALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWH-WTAFAGILRQSF 319
Query: 102 LSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHT----PLCLPQPAHRFPFGAS 157
+ GA + P Y+ ++ +D+AL++L P T P+CLP P
Sbjct: 320 MFYGAGYQVEKVISHPN-YDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQL 378
Query: 158 CWATGW--DQDTSDAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPG 215
CW +GW ++ L ++ LI CN Y N P M+C G G
Sbjct: 379 CWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRY------VYDNLITPAMICAGFLQG 432
Query: 216 VQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWL--QARVQ 273
CQGDSGGP L + W G S+ S CA+ P + N + W+ Q R
Sbjct: 433 NVDSCQGDSGGP-LVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRAD 491
Query: 274 G 274
G
Sbjct: 492 G 492
Score = 112 bits (279), Expect = 1e-24
Identities = 70/248 (28%), Positives = 111/248 (44%), Gaps = 23/248 (9%)
Query: 293 CVACG-------SLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCF-I 344
C+ACG R G ++ P WPW+ L Q CGG++++ E ++TAAHC
Sbjct: 241 CIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEK 300
Query: 345 GRQAPEEWSVGLGTRPEE-------WGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGAS 397
P W+ G + + ++++I H Y D+AL+ L +P+T
Sbjct: 301 PLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDL 360
Query: 398 LRPLCLPYPDHHLPDGERGWVLG---RARPGAGISSLQTVPVTLLGPRACSRLHAAPGGD 454
++P+CLP P L + W+ G G L V L+ + C+ +
Sbjct: 361 VKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVY---- 416
Query: 455 GSPILPGMVCTSAV-GELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTA 513
+ I P M+C + G + SC+G SG PLV W+L G S+G C RP V+
Sbjct: 417 DNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGN 476
Query: 514 LPAYEDWV 521
+ + DW+
Sbjct: 477 VMVFTDWI 484
>gi|194018492 transmembrane protease, serine 11F [Homo sapiens]
Length = 438
Score = 122 bits (307), Expect = 7e-28
Identities = 80/237 (33%), Positives = 118/237 (49%), Gaps = 28/237 (11%)
Query: 46 GEWPWQASVRRQGA-HICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSP 104
GEWPWQAS++ G+ H C SL+++TW+LTAAHCF K + W G+ ++P
Sbjct: 216 GEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWK--NKDPTQWIATFGAT----ITP 269
Query: 105 GAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHTPL----CLPQPAHRFPFGASCWA 160
A + V + L Y+ + +D+AL+QL+ + + CLP + + P S +
Sbjct: 270 PAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSVFV 329
Query: 161 TGWDQDTSDAP--GTLRNLRLRLISRPTCN--CIYNQLHQRHLSNPARPGMLCGGPQPGV 216
TG+ D P TLR R+ IS CN +Y+ L PGMLC G G
Sbjct: 330 TGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGL--------ITPGMLCAGFMEGK 381
Query: 217 QGPCQGDSGGPVLCLEPDGH--WVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQAR 271
C+GDSGGP++ D H W GI+S+ SCA P + T + W+ ++
Sbjct: 382 IDACKGDSGGPLVY---DNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWIASK 435
Score = 112 bits (281), Expect = 7e-25
Identities = 71/230 (30%), Positives = 113/230 (49%), Gaps = 13/230 (5%)
Query: 303 GPQAGAPSPWPWEARLMHQGQ-LACGGALVSEEAVLTAAHCFIGRQAPEEWSVGLG---T 358
G + WPW+A L G CG +L+S +LTAAHCF + P +W G T
Sbjct: 209 GRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQWIATFGATIT 268
Query: 359 RPE-EWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGERGW 417
P + ++++ILH Y D+AL+ L+ V ++ +CLP LP +
Sbjct: 269 PPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSVF 328
Query: 418 VLGRAR---PGAGISSLQTVPVTLLGPRACSRLHAAPGGDGSPILPGMVCTSAV-GELPS 473
V G G ++L+ V + C+R G I PGM+C + G++ +
Sbjct: 329 VTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDG----LITPGMLCAGFMEGKIDA 384
Query: 474 CEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSS 523
C+G SG PLV++ W++ G+ S+G +C P +P V+T + Y DW++S
Sbjct: 385 CKGDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWIAS 434
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,615,536
Number of Sequences: 37866
Number of extensions: 1622099
Number of successful extensions: 5940
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 165
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 4726
Number of HSP's gapped (non-prelim): 637
length of query: 553
length of database: 18,247,518
effective HSP length: 107
effective length of query: 446
effective length of database: 14,195,856
effective search space: 6331351776
effective search space used: 6331351776
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.