Guide to the Human Genome
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Search of human proteins with 84662750

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|84662750 hypothetical protein LOC284083 [Homo sapiens]
         (570 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|84662750 hypothetical protein LOC284083 [Homo sapiens]            1166   0.0  
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    48   3e-05
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        43   9e-04
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        42   0.001
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        42   0.001
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         42   0.002
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    42   0.002
gi|153251865 hypothetical protein LOC84226 [Homo sapiens]              41   0.003
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]    41   0.003
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]                41   0.003
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]                41   0.003
gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti...    40   0.006
gi|148612879 polyhomeotic like 3 [Homo sapiens]                        40   0.006
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         40   0.006
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]     40   0.006
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]     40   0.006
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             39   0.010
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        39   0.013
gi|22035604 mitogen-activated protein kinase kinase kinase kinas...    39   0.013
gi|169218320 PREDICTED: similar to BCL2-associated transcription...    39   0.017
gi|117938254 BCL2-associated transcription factor 1 isoform 3 [H...    39   0.017
gi|117938251 BCL2-associated transcription factor 1 isoform 2 [H...    39   0.017
gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Hom...    39   0.017
gi|239582741 FERM and PDZ domain containing 1 [Homo sapiens]           38   0.022
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    38   0.022
gi|91208420 bassoon protein [Homo sapiens]                             38   0.022
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     38   0.022
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          38   0.029
gi|60097902 filaggrin [Homo sapiens]                                   38   0.029
gi|83367077 mucin 16 [Homo sapiens]                                    38   0.029

>gi|84662750 hypothetical protein LOC284083 [Homo sapiens]
          Length = 570

 Score = 1166 bits (3017), Expect = 0.0
 Identities = 570/570 (100%), Positives = 570/570 (100%)

Query: 1   MVKTNKPGAKVAVSAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTT 60
           MVKTNKPGAKVAVSAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTT
Sbjct: 1   MVKTNKPGAKVAVSAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTT 60

Query: 61  PHSASDYPRSVSLQSGPGHYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHASSRQ 120
           PHSASDYPRSVSLQSGPGHYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHASSRQ
Sbjct: 61  PHSASDYPRSVSLQSGPGHYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHASSRQ 120

Query: 121 WKVSPPREEAARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSK 180
           WKVSPPREEAARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSK
Sbjct: 121 WKVSPPREEAARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSK 180

Query: 181 VQNPQGARVPRRILSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQ 240
           VQNPQGARVPRRILSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQ
Sbjct: 181 VQNPQGARVPRRILSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQ 240

Query: 241 RRVPVEESETGPYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYS 300
           RRVPVEESETGPYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYS
Sbjct: 241 RRVPVEESETGPYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYS 300

Query: 301 AYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSEGSH 360
           AYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSEGSH
Sbjct: 301 AYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSEGSH 360

Query: 361 KSSMFVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKPSIHAELELTPRPLPPRSLPR 420
           KSSMFVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKPSIHAELELTPRPLPPRSLPR
Sbjct: 361 KSSMFVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKPSIHAELELTPRPLPPRSLPR 420

Query: 421 YGPDSSWWPLLNPEVETPQSQLTTPDFEPKCSPSLDLLLSGFKIDSSPFCEDLKFQREKA 480
           YGPDSSWWPLLNPEVETPQSQLTTPDFEPKCSPSLDLLLSGFKIDSSPFCEDLKFQREKA
Sbjct: 421 YGPDSSWWPLLNPEVETPQSQLTTPDFEPKCSPSLDLLLSGFKIDSSPFCEDLKFQREKA 480

Query: 481 SLSPPSPPKEFPSWAPLSEVPQTPKHTCKQPIQRFTAFFLDVSEEMYNRVIWWLKGLCFS 540
           SLSPPSPPKEFPSWAPLSEVPQTPKHTCKQPIQRFTAFFLDVSEEMYNRVIWWLKGLCFS
Sbjct: 481 SLSPPSPPKEFPSWAPLSEVPQTPKHTCKQPIQRFTAFFLDVSEEMYNRVIWWLKGLCFS 540

Query: 541 LLWAHCGSLGDGRTGEEWHLCIYRAGSFRR 570
           LLWAHCGSLGDGRTGEEWHLCIYRAGSFRR
Sbjct: 541 LLWAHCGSLGDGRTGEEWHLCIYRAGSFRR 570


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 119/502 (23%), Positives = 168/502 (33%), Gaps = 73/502 (14%)

Query: 27  PQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSLQSGPGHYAVPTPR 86
           P +G    ++S+   +    +P+ RR  +A           P S SL S     A P   
Sbjct: 201 PTEGPRKSVSSASEHSTTEPSPAARRRPSAG-----GGLQRPASRSLSSS----ATPLSS 251

Query: 87  GTETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARR-GSESKSGREVGH 145
              +GP    +  +  H    K + L +    R  +V+PPR++AA   G  S S      
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQA---LRPPQVTPPRKDAAPALGPLSSSPL---- 304

Query: 146 HASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQ---NPQGARVPRRILSYPKDEAV 202
            A+  P       +   D         L   PP        P     P  + + P   A 
Sbjct: 305 -ATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT 363

Query: 203 QTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRVPVEESETGPYGPIPSKPKA 262
                    TT  +++P  PSL            QT    + V  S T P    P  P A
Sbjct: 364 PPSQAPPSMTTPPMQAP--PSL------------QTIPP-IQVPHSLTSPSLQAPPSPLA 408

Query: 263 LYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYSAYPETKPSAKVLVSSQVESNVR 322
           L  ++   + L    L+ +     +S R    SL   S    T P +  L         +
Sbjct: 409 L-SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPL---------Q 458

Query: 323 TPIRGNSEVGRRVTISPGVQSVEP--THHVTVPSVSEGSHKS----SMFVTPEPIYKQQT 376
            P+   +    + ++SP V  +    T H      S  SH      S  + P P+  Q +
Sbjct: 459 APLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMP-PLETQSS 517

Query: 377 QKPPEI----TYMSQGPTPRYPELSQKPSIHAELELTP----RPLPPRSLPRYGPDSSWW 428
             PP +      ++  P    P L+  P   A   LT      P  P   P   P S   
Sbjct: 518 LAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPS--- 574

Query: 429 PLLNPEVETPQSQLTTPDFEPKC--SPSLDLLLSGFKIDSSPFCEDLKFQREKASL---- 482
           PL  P  ETP S  T P   P    SP L  L S      SP            +L    
Sbjct: 575 PLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP---PLSPLATPPPQAPPXLALPPLQ 631

Query: 483 SPPSPPKEFPSWAPLSEVPQTP 504
           +PPSPP   P     +  PQ P
Sbjct: 632 APPSPPASPPLSPLATPSPQAP 653



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 53/207 (25%), Positives = 70/207 (33%), Gaps = 36/207 (17%)

Query: 340 GVQSVEPTHHVTVP----SVSEGSHKSSMFVTPEPIYKQQTQKPPEITYMSQGPT--PRY 393
           G+Q++ P   VT P    + + G   SS   TP P   +    PP     +  P   P  
Sbjct: 276 GLQALRPPQ-VTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPS 334

Query: 394 PELSQK-----PSIHAELELTPRPLPPRSLPRYGPDSSWWPLLN--------PEVETPQS 440
           P L+       PS  A   L   P PP + P   P S   P +         P ++ P S
Sbjct: 335 PPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHS 394

Query: 441 QLTTPDFEPKCSPSLDLLLSGFKIDSSPFCE---------------DLKFQREKASLSPP 485
            LT+P  +   SP     L       SP  +                L      AS  P 
Sbjct: 395 -LTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453

Query: 486 SPPKEFPSWAPLSEVPQTPKHTCKQPI 512
           SPP + P   P S   QT       P+
Sbjct: 454 SPPLQAPLSLPASPPLQTSLSPAVSPL 480



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 41/149 (27%), Positives = 54/149 (36%), Gaps = 30/149 (20%)

Query: 380 PEITYMSQGPTP-RYPELSQKPSIHAELELTPRPLPPRSLPRYGPDSSWWPLLNPEVETP 438
           P  T  SQ P     P L   PS  A   ++P   PP   P         PL  P ++ P
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP--------PLAAPPLQVP 738

Query: 439 QSQLTTPDFEPKCSPS--LDLLLSG----------FKIDSSPFCEDLKFQREKASLSPP- 485
            S   +P   P  +P   +  LL+             +  SP  +    Q   A  +PP 
Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP-QAPPALATPPL 797

Query: 486 ----SPPKEFPSWAPLS---EVPQTPKHT 507
               SPP  FP  AP S    +P +P  T
Sbjct: 798 QALPSPPASFPGQAPFSPSASLPMSPLAT 826


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 109/533 (20%), Positives = 195/533 (36%), Gaps = 84/533 (15%)

Query: 3    KTNKPGAKVAVSAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPS-------HRRSEA 55
            KT + G++ A  A   SE+      +  H      + +S+ ++  P+       H  +  
Sbjct: 1080 KTRQDGSQEAPEAPLSSEL------EPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTST 1133

Query: 56   AHPTTPHSASDYPRSVSLQSGPGHYAVPTPRG-TETGPRTESSRHSSPHLKSQKTQTLAS 114
            A P TP   S   RS + +S     +V TP     T P  + S  +   + S+ T  +  
Sbjct: 1134 AQPVTPKPTSQATRSRTNRS-----SVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTR 1188

Query: 115  HASSRQWKVSPPREEAARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILE 174
               SR    +P  E       E +         +S P +++T     + +KN    +  E
Sbjct: 1189 GRKSRSSVKTP--ETVVPTALELQPSTSTDRPVTSEPTSQAT-----RGRKNRSSVKTPE 1241

Query: 175  DDPPSKVQNPQGARVPRRILSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSS---- 230
               P+  +        + + S P  +A +    +    T E   P +P L    S+    
Sbjct: 1242 PVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPV 1301

Query: 231  CVSADYQTAQRRVPVEESETGPYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSAR 290
                  +T + R  +   +T P   +P+ P+           L++S   D     + ++R
Sbjct: 1302 TPKPTSRTTRSRTNMSSVKT-PETVVPTAPE-----------LQISTSTDQPVTPKPTSR 1349

Query: 291  VDPESLHKYSAYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHV 350
                  +  S      P + V ++ ++  +  T      E   R T     +S   T   
Sbjct: 1350 TTRSRTNMSSV---KNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPET 1406

Query: 351  TVPSVS--EGSHKSSMFVTPEPIYK-------QQTQKPPEITYMSQGPTPRYPELSQKPS 401
             VP+    E S  +   VTPEP  +       + + K PE         P  PEL  +PS
Sbjct: 1407 LVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETV------VPTAPEL--QPS 1458

Query: 402  IHAELELTPRPLPPRSLPRYGPDSSWWPLLNPEVETPQSQLTTPDFEPKCSPSLDLLLSG 461
               +  +TP P    +  R    S         V+TP++ + T   E + S S D     
Sbjct: 1459 TSTDQPVTPEPTSQATRGRTDRSS---------VKTPETVVPTAP-ELQASASTDQ---- 1504

Query: 462  FKIDSSPFCEDLKFQREKASLSP-----PSPPKEFPSWAPLSEVPQTPKHTCK 509
              + S P     + ++ ++S+       P+ P+  PS +  ++ P TP+ T +
Sbjct: 1505 -PVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTS--TDQPVTPEPTSR 1554



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 93/456 (20%), Positives = 156/456 (34%), Gaps = 65/456 (14%)

Query: 77   PGHYAVPTPRGTETGPR---TESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARR 133
            PG  + P P G+++G R       RH    L  +                 PP E+A+R 
Sbjct: 977  PGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCK----------------MPPAEKASRI 1020

Query: 134  GSESKSGREVGHHAS-------SIPDAKSTHQ--LSFQDQKNNLQSQILEDDPPSKVQNP 184
             +  K  R  G   S       ++P+A +  Q  L+ Q QK+     +L    PS     
Sbjct: 1021 RAAEKVSR--GDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPT- 1077

Query: 185  QGARVPRRILSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRVP 244
               R  R+  S    EA  +  ++      +IR+ +S  +              A    P
Sbjct: 1078 --VRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPF----------PATSAAP 1125

Query: 245  VEESETGPYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYSAYPE 304
                 T    P+  KP     +    S    S +K  + V   +  + P +        E
Sbjct: 1126 EPHPSTSTAQPVTPKP----TSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSE 1181

Query: 305  TKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSEGSHKSSM 364
              P+++V    +  S+V+TP    + V   + + P   +  P         + G    S 
Sbjct: 1182 --PTSQVTRGRKSRSSVKTP---ETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSS 1236

Query: 365  FVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKPSIHAELELTPRPLPPRSLPRYGPD 424
              TPEP+     +  P  T   Q  T      + +   +     TP P+ P + P   P 
Sbjct: 1237 VKTPEPVVPTAPELQPS-TSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVP-TAPELRPS 1294

Query: 425  SSWWPLLNPE-------VETPQSQLTTPDFEPKCSPSLDLLLSGFK-IDSSPFCEDLKFQ 476
            +S    + P+         T  S + TP+     +P L +  S  + +   P     + +
Sbjct: 1295 TSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSR 1354

Query: 477  REKASLSPPSPPKEFPSWAPLS---EVPQTPKHTCK 509
               +S+  P          P S   E P TP+ T +
Sbjct: 1355 TNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSR 1390


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 100/450 (22%), Positives = 154/450 (34%), Gaps = 89/450 (19%)

Query: 14   SAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSL 73
            + ++G   T  + P          +  SA V L+ +   S ++ PTT  SAS      S 
Sbjct: 1823 TTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSE 1882

Query: 74   QSGPGHYA------VPTP-RGTETGPRTESSR-HSSP------HLKSQKT------QTLA 113
            +S   H +       P+P R T +G   ES+  HSSP      H     T      ++  
Sbjct: 1883 ESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 1942

Query: 114  SHASSRQWKVSPPREEAAR-------------------RGSESKSGR---EVGHHASS-- 149
            SH+S+     SPP   +A                      S + SGR       H+S   
Sbjct: 1943 SHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDA 2002

Query: 150  -----IPDAKSTHQLSFQDQKNNLQSQILEDDP-PSKVQNPQGARVPRRILSYPKDEAVQ 203
                 +P   +T  L  +   + + S  +E    P     P  +       S P+  A  
Sbjct: 2003 TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATT 2062

Query: 204  TEP-------IQRITTTSEIR-----------SPRSPSLLEHGSSCVSADYQTAQRRVPV 245
              P       +   +TTS  R           S  +P L  H ++  S+   T    +P 
Sbjct: 2063 LSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 2122

Query: 246  EESETGPYGPIP---SKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYSAY 302
              + +GP        S P +    ++  S   LS  ++S   H       P S H     
Sbjct: 2123 STTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHS-----SPGSTHTTLFP 2177

Query: 303  PETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSEGSHKS 362
              T  S  V  S++V S+  +P    + +    + SPG+Q           S +  +H +
Sbjct: 2178 DSTTSSGIVEASTRVHSSTGSP---RTTLSPASSTSPGLQG---------ESTAFQTHPA 2225

Query: 363  SMFVTPEPIYKQQTQKPPEITY-MSQGPTP 391
            S   TP P            TY  S G TP
Sbjct: 2226 STHTTPSPPSTATAPVEESTTYHRSPGSTP 2255



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 106/464 (22%), Positives = 149/464 (32%), Gaps = 66/464 (14%)

Query: 14  SAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSL 73
           +   G   T  + P         S   SA V L+ ++  S ++ PTT  SAS      S 
Sbjct: 412 TTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSE 471

Query: 74  QSGPGHYA------VPTPRGTETGPRTESSR--HSSP------HLKSQKT------QTLA 113
           +S P H +       P P  + T    E S   H SP      H     T      ++  
Sbjct: 472 ESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESAT 531

Query: 114 SHASSRQWKVSPPREEAAR-----------------RGSESKSGREVGHHAS-SIPDAKS 155
            H S+   K S P   AA                  R S + SGR     AS S PDA +
Sbjct: 532 FHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMA 591

Query: 156 THQLSFQDQKNNLQSQILEDDPPSKVQNPQGARVPRRILSYPKDEAVQTEPIQRITTTSE 215
           T  L       +  S ++ D  PS + +          +         T+P     +T+ 
Sbjct: 592 TTVL----PAGSTPSVLVGDSTPSPISSGS--------METTALPGSTTKPGLSEKSTTF 639

Query: 216 IRSPRSPSLLEHGSSCVSADYQTAQRRVPVEESETGPYGPIPSKPKALYRNMNLDSLLKL 275
             SPRSP      +S  S+           EES T    P  +   A   +  +  L + 
Sbjct: 640 YSSPRSPDTTHLPASMTSSGVS--------EESTTSHSRPGSTHTTAFPGSTTMPGLSQE 691

Query: 276 SVLKDSDGVHRVSARVDPESLHKYSAYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRV 335
           S    S         + P S    S  PE          S+  S   T +  N+     +
Sbjct: 692 STASHS-SPGPTDTTLSPGSTTASSLGPE-----YTTFHSRPGSTETTLLPDNTTASGLL 745

Query: 336 TISPGVQSVEPTHHVTV-PSVSEGSHKSSMFVTPEPIYKQQTQKPPEITYMSQGP-TPRY 393
             S  V S   + H T+ P+ S      S      P  K     PP  T     P T  +
Sbjct: 746 EASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSH 805

Query: 394 PELSQKPSIHAELELTPRPLPPRSLPRYGPDSSWWPLLNPEVET 437
              S  P+ H     T   L   S   +    S   +  PE +T
Sbjct: 806 GSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDT 849



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 87/416 (20%), Positives = 136/416 (32%), Gaps = 54/416 (12%)

Query: 3    KTNKPGAKVAVSAQRGSEVTTNTSPQQ-GHGYVLASSHRSAAVSLNPSHRRSEAAHPTTP 61
            K  +P      SA      T++ SP      ++ A S  S  V  + ++  S  +  T  
Sbjct: 784  KDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMH 843

Query: 62   HSASDYP-----RSVSLQSGPGHYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHA 116
               SD        S +  S   H     P  T       +S HSSP        T  +H 
Sbjct: 844  FPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPG------STATTHF 897

Query: 117  SSRQWKVSPPREEAARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDD 176
                       E  A   S+  +G  V      +P   +T  L  +   + + S  +E  
Sbjct: 898  PDSSTTSGRSEESTASHSSQDATGTIV------LPARSTTSVLLGESTTSPISSGSMETT 951

Query: 177  P-PSKVQNPQGARVPRRILSYPKDEAVQTEP-------IQRITTTSEIR----------- 217
              P     P  +       S P+  A    P       +   +TTS  R           
Sbjct: 952  ALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPD 1011

Query: 218  SPRSPSLLEHGSSCVSADYQTAQRRVPVEESETGPYGPIPSKPKALYRNMNLDSLLKL-S 276
            S  +P L  H ++  S+   T    +P   + +GP     +   +   + + D+ L   S
Sbjct: 1012 STTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS---SGSTDTALSPGS 1068

Query: 277  VLKDSDGVHRVSARVDPESLHKYSAYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVT 336
                S G    +   +P S H       T  S  V  S++V S+  +P    + +    +
Sbjct: 1069 TTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP---RTTLSPASS 1125

Query: 337  ISPGVQSVEPTHHVTVPSVSEGSHKSSMFVTPEPIYKQQTQKPPEITY-MSQGPTP 391
             SPG+Q           S +  +H +S   TP P            TY  S G TP
Sbjct: 1126 TSPGLQG---------ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 1172



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 89/406 (21%), Positives = 133/406 (32%), Gaps = 60/406 (14%)

Query: 18   GSEVTTNTS-PQQGHGYVLASS-------HRSAAVSLNPSHRRSEAAHPTTPHSASDYPR 69
            G E TT+ S P   H  V  +S         S  V  +          P TP ++     
Sbjct: 2352 GEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEE 2411

Query: 70   SVSLQSGPG--HYAVPTPRGTETGPRTESSRHSSPHLKSQ--------------KTQTLA 113
              +  S P   H  + T   T +G   ES+        +Q              ++ T  
Sbjct: 2412 PTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFP 2471

Query: 114  SHASSRQWKVSPPREEAARRGSESKSGR--EVGHHASSIPDAKSTHQLSFQDQKNNLQSQ 171
            S + S    +SP R   +    ES   R        +++P + +T  LS +       S 
Sbjct: 2472 SSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEK-------ST 2524

Query: 172  ILEDDPPSKVQNPQGARVPRRILSYPKDEAVQTEPIQ--RITTTSEIRSPRSPSLLEHGS 229
                 P S    P     P    S    E   T   Q     TT+   S  +P L  H +
Sbjct: 2525 TFYTSPRS----PDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHST 2580

Query: 230  SCVSADYQTAQRRVPVEESETGPYGPIP---SKPKALYRNMNLDSLLKLSVLKDSDGVHR 286
            +  S+   T    +P   + +GP        S P +    ++  S   LS  ++S   H 
Sbjct: 2581 TSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHS 2640

Query: 287  VSARVDPESLHKYSAYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEP 346
                  P S H       T  S  V  S++V S+  +P    + +    + SPG+Q    
Sbjct: 2641 -----SPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP---RTTLSPASSTSPGLQGEST 2692

Query: 347  THHVTVPSVSEGSHKSSMFVTPEPIYKQQTQKPPEITY-MSQGPTP 391
            T           +H +S   TP P            TY  S G TP
Sbjct: 2693 TFQ---------THPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 2729



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 52/217 (23%), Positives = 79/217 (36%), Gaps = 10/217 (4%)

Query: 14   SAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSL 73
            + ++G   T  + P          +  SA V L+ +   S ++ PTT  SAS      S 
Sbjct: 3380 TTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSE 3439

Query: 74   QSGPGHYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARR 133
            +S   H    +P  T T P    +R ++  L  + T T  S   S Q    P  +  + R
Sbjct: 3440 ESTTVH---SSPVATATTP--SPARSTTSGLVEEST-TYHSSPGSTQTMHFPESDTTSGR 3493

Query: 134  GSES-KSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNPQGARVPRR 192
            G ES  S     H  SS P   S          ++  S      P S   +    R    
Sbjct: 3494 GEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTS---GRSEES 3550

Query: 193  ILSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGS 229
              S+   +A  T  +   +TTS +    + S +  GS
Sbjct: 3551 TASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 3587



 Score = 32.7 bits (73), Expect = 0.92
 Identities = 52/217 (23%), Positives = 78/217 (35%), Gaps = 10/217 (4%)

Query: 14   SAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSL 73
            + ++G   T  + P          +  SA V L+ +   S ++ PTT  SAS      S 
Sbjct: 4463 TTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSE 4522

Query: 74   QSGPGHYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARR 133
            +S   H    +P  T T P    +R ++  L  + T T  S   S Q    P     + R
Sbjct: 4523 ESTTVH---SSPVATATTP--SPARSTTSGLVEEST-TYHSSPGSTQTMHFPESNTTSGR 4576

Query: 134  GSES-KSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNPQGARVPRR 192
            G ES  S     H  SS P   S          ++  S      P S   +    R    
Sbjct: 4577 GEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTS---GRSEES 4633

Query: 193  ILSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGS 229
              S+   +A  T  +   +TTS +    + S +  GS
Sbjct: 4634 TASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 4670



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 6/102 (5%)

Query: 17   RGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSLQSG 76
            +G   T  T P   H      S  +A V  + ++ RS  + PTT   AS      S +S 
Sbjct: 2688 QGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKST 2747

Query: 77   PGHYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHASS 118
              H + P   GT     T SS HS+   + + T +  S  S+
Sbjct: 2748 IFH-SSPDASGT-----TPSSAHSTTSGRGESTTSRISPGST 2783


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 109/521 (20%), Positives = 190/521 (36%), Gaps = 70/521 (13%)

Query: 14   SAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSL 73
            ++QR S   +N+SP+     +  SS RS ++S   S  +S  +   +   +S  P+  S 
Sbjct: 736  TSQRRSR--SNSSPEMKKSRI--SSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKS- 790

Query: 74   QSGP--GHYAVPTPRG-TETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEA 130
            Q+ P         P+  + T PR   S  S P  +  KT +  SH+SS     SP     
Sbjct: 791  QTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSS-----SP--HPK 843

Query: 131  ARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNP-----Q 185
             + G+  + G        SI   ++  Q     +++  +S     DP  K + P      
Sbjct: 844  VKSGTPPRQG--------SITSPQANEQSVTPQRRSCFES---SPDPELKSRTPSRHSCS 892

Query: 186  GARVPRRILSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRVPV 245
            G+  PR   S P  ++    P +  +   ++++  SP    H  S   +  +   R  P 
Sbjct: 893  GSSPPRVKSSTPPRQS----PSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPR 948

Query: 246  EESETGPYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYSAYPET 305
                  P   + S+    Y +              S    +V     P   H  S  P  
Sbjct: 949  RSRSVSPCSNVESRLLPRYSHSG-----------SSSPDTKVKPETPPRQSHSGSISPYP 997

Query: 306  KPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSEGSHKSSMF 365
            K  A+      + S  ++P          V   PG  S+      + P         S F
Sbjct: 998  KVKAQTPPGPSL-SGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPP------GESYF 1050

Query: 366  VTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKPSIHAELELTPRPLPPRSLPRYGPDS 425
                   K Q+Q  P+    +  P  R    S+ PS+ ++ + +P+    RS       +
Sbjct: 1051 GVSSLQLKGQSQTSPDHRSDTSSPEVRQSH-SESPSLQSKSQTSPKGGRSRSSSPVTELA 1109

Query: 426  SWWPLLNPEVETPQSQLTTPDFEPKCS---------PSLD--LLLSGFKIDSSPFCEDLK 474
            S  P+     E   S +      P+ S         P++D   LL   +++++   E + 
Sbjct: 1110 SRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMA 1169

Query: 475  F-QREKASLSPPSPPKEFPSWAPLSEVPQTP---KHTCKQP 511
               +E A+ SPP    +F  + P+ + P++    K T + P
Sbjct: 1170 LPPQEDATASPPRQKDKFSPF-PVQDRPESSLVFKDTLRTP 1209



 Score = 37.7 bits (86), Expect = 0.029
 Identities = 106/470 (22%), Positives = 164/470 (34%), Gaps = 64/470 (13%)

Query: 14  SAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSL 73
           SA+RG   + + + + G       + R  + S  P+ RRS +  PT   S S  P     
Sbjct: 556 SARRGRSHSRSPATR-GRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTP----A 610

Query: 74  QSGPGHYAVPTPRGTET-GPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAAR 132
           + G      P  R + T  P    SR  SP  +S ++++       R    +P R   +R
Sbjct: 611 RRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSR 670

Query: 133 -RGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNPQGARVPR 191
            R    +SGR     + S   A+     S   ++   +S+ L     S  + PQ  R   
Sbjct: 671 SRTPARRSGR-----SRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQ-RRGRS 724

Query: 192 RILSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRVPVEESETG 251
              S  K+++  ++   R  ++ E++  R  S     S  +S+    A+ R+ +  S +G
Sbjct: 725 GSSSERKNKSRTSQRRSRSNSSPEMKKSRISS---RRSRSLSSPRSKAKSRLSLRRSLSG 781

Query: 252 PYGPIP---------------SKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESL 296
              P P               S+PKA  R        + S    S    + S     +S 
Sbjct: 782 S-SPCPKQKSQTPPRRSRSGSSQPKAKSRTPP-----RRSRSSSSPPPKQKSKTPSRQSH 835

Query: 297 HKYSAYPETK----PSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTV 352
              S +P+ K    P    + S Q      TP R +       +  P ++S  P+ H   
Sbjct: 836 SSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSC---FESSPDPELKSRTPSRH--- 889

Query: 353 PSVSEGSHKSSMFVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKPSIHAELELTPRP 412
            S S  S       TP      ++  P         P  R    S  PS      +T R 
Sbjct: 890 -SCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPS---PSRVTSRT 945

Query: 413 LPPRS-------------LPRYGPDSSWWPLLNPEVETPQSQLTTPDFEP 449
            P RS             LPRY    S  P    + ETP  Q  +    P
Sbjct: 946 TPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISP 995



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 39/174 (22%), Positives = 64/174 (36%), Gaps = 24/174 (13%)

Query: 2    VKTNKPGAKVAVSAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTP 61
            V +  P  K AV   R  E T     ++      +SS  S++ S + S   S ++  ++ 
Sbjct: 2579 VPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2638

Query: 62   HSASDYPRSVSLQSGPGHYAVPTPRGTETGPRTE------------------------SS 97
             S+S    S    + PG  A+P P   +  P  E                          
Sbjct: 2639 SSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVER 2698

Query: 98   RHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSESKSGREVGHHASSIP 151
            R  SP    +  Q+ +S   SR+ +    R  + +R  E+ S R + H +S  P
Sbjct: 2699 RRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752



 Score = 33.1 bits (74), Expect = 0.70
 Identities = 33/121 (27%), Positives = 46/121 (38%), Gaps = 15/121 (12%)

Query: 46  LNPSHRRSEAAHPTTPHSASDYPRSVSLQSGP--------GHYAVPTPRGTETGPRTESS 97
           +NP    S     + P S    P+S S +S P          +A  +P   +  P   S 
Sbjct: 391 VNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSH 450

Query: 98  RH--SSPHLKSQ-----KTQTLASHASSRQWKVSPPREEAARRGSESKSGREVGHHASSI 150
           R   SSP  K++     K     SH  SR+   S     A R  S S++  + GH  S  
Sbjct: 451 REISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRS 510

Query: 151 P 151
           P
Sbjct: 511 P 511



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 86/368 (23%), Positives = 124/368 (33%), Gaps = 61/368 (16%)

Query: 25   TSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSAS-------DYPRSVSLQSGP 77
            +SP+   G     S RS + S +P  R  + +   + HS S       D PR+ S     
Sbjct: 1423 SSPEMKDGLPRTPSRRSRSGS-SPGLR--DGSGTPSRHSLSGSSPGMKDIPRTPSRGRSE 1479

Query: 78   GHYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSES 137
               + P P+     PR  S   SSP L + K  T     S  +  V          G  S
Sbjct: 1480 CDSS-PEPKALPQTPRPRSRSPSSPEL-NNKCLTPQRERSGSESSVDQKTVARTPLGQRS 1537

Query: 138  KSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNPQGARVPRRILSYP 197
            +SG              S+ +L  +   +  +    +  P SK +     R   R  S P
Sbjct: 1538 RSG--------------SSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSP 1583

Query: 198  KDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRVPVEESETGPYGPIP 257
            + ++               +S  SP     GSS    D   A  R     S++ P    P
Sbjct: 1584 EVDS---------------KSRLSPRRSRSGSSPEVKDKPRAAPRAQ-SGSDSSPEPKAP 1627

Query: 258  SKPKALYRNMNLDSLLK-------LSVLKDSDGVHRVSARVDPESLHKYSAYPETKPSAK 310
            + P+AL R     S  K        S   +S   H   +R       + S  P+TK    
Sbjct: 1628 A-PRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRG-SRSSPEPKTKSRTP 1685

Query: 311  VLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSEGSHKSSMFVTPEP 370
                S   S   T     S   R  + SP  +S  P  H   PSVS          +PEP
Sbjct: 1686 PRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVS----------SPEP 1735

Query: 371  IYKQQTQK 378
              K ++ +
Sbjct: 1736 AEKSRSSR 1743



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 36/135 (26%), Positives = 48/135 (35%), Gaps = 13/135 (9%)

Query: 37   SSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSLQSGPGHYAVPTPRGTETGPRTES 96
            SS      S  P  RRS  + P     A    RS S  S P           ET  RT  
Sbjct: 1674 SSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSP-----------ETRSRTPP 1722

Query: 97   SRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSESKSGREVG-HHASSIPDAKS 155
                SP + S +     S +S R+   S PR +   R   S S +  G   + S    + 
Sbjct: 1723 RHRRSPSVSSPEPAE-KSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREK 1781

Query: 156  THQLSFQDQKNNLQS 170
            T     +D+  + QS
Sbjct: 1782 TRTTRRRDRSGSSQS 1796



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 9/135 (6%)

Query: 14   SAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSA----SDYPR 69
            SA    E  + T P+  H    + S    A     S RR  A+ P T  ++    S  P+
Sbjct: 1709 SASSSPETRSRTPPR--HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK 1766

Query: 70   SVSLQSGPGHYAVPTPRGTETGPRTESSRHSS---PHLKSQKTQTLASHASSRQWKVSPP 126
               LQ           R T    R+ SS+ +S      +S+   T      S     SP 
Sbjct: 1767 PRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPA 1826

Query: 127  REEAARRGSESKSGR 141
            R+E++R  S  + GR
Sbjct: 1827 RQESSRTSSRRRRGR 1841


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 116/548 (21%), Positives = 177/548 (32%), Gaps = 110/548 (20%)

Query: 37  SSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSLQSGPGHYAVPTPRGTETGPRTES 96
           S  RS   S +PSH R    H +   S S   R  S +  P       PR     PR   
Sbjct: 282 SKSRSRTRSRSPSHTRPRRRHRSRSRSYSP-RRRPSPRRRPSPRRRTPPRRMPPPPRHRR 340

Query: 97  SRHSSP---HLKSQKTQTLASHASSRQWKVSPPREEAARRGSESKSGREVGHHAS----- 148
           SR  SP     +S  + + +S +SS     SPP++   R  S  +  R +   AS     
Sbjct: 341 SR--SPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRR 398

Query: 149 ------SIPDAKSTHQLSFQDQKNNLQS-----------QILEDDPPSKVQNPQGARVPR 191
                 + P  K+ H  + Q      +S           ++ +     K ++P  A  PR
Sbjct: 399 HRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPR 458

Query: 192 RI--LSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRVPVEESE 249
           ++      +D+  +      +    + R     S  + GSS  S D +   +R  V+  E
Sbjct: 459 KVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDER--PKRSHVKNGE 516

Query: 250 TG------PYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYSAYP 303
            G      P       P+   +  +     + S         R  +   P    +     
Sbjct: 517 VGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRR----T 572

Query: 304 ETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSEGSHKSS 363
            T P  +   S        +P R +  + RR + SP      P      P          
Sbjct: 573 PTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSP-----PPKRRTASP---------- 617

Query: 364 MFVTPEPIYKQQTQKPPEITYMSQGPTP----------RYPELSQK-------------- 399
               P P  ++ +  PP    +S  P P          R P LS K              
Sbjct: 618 ----PPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREA 673

Query: 400 --PSIHAELELTPRPLPPRSLP-----RYGPDSSWWPLLNPEVETPQSQLTTPDFEPK-- 450
             P  +     +PRP  P++       R G  SS     +P   T   +  +   EPK  
Sbjct: 674 RSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKI 733

Query: 451 ---CSP---SLDLLLSGFKIDSSPFCEDLKFQREKASLSPPSPPKEFPSWAPLSE-VPQT 503
               SP   S+  + S   +  SP         E A+  PP+PP    S +P +   P  
Sbjct: 734 KKAASPSPQSVRRVSSSRSVSGSP---------EPAAKKPPAPPSPVQSQSPSTNWSPAV 784

Query: 504 PKHTCKQP 511
           P    K P
Sbjct: 785 PVKKAKSP 792



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 46/178 (25%), Positives = 72/178 (40%), Gaps = 21/178 (11%)

Query: 16  QRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSLQS 75
           QR S VT   SP       L+S HR  + S + S R + +  P   HS S  PR+    S
Sbjct: 643 QRSSPVTKRRSPS------LSSKHRKGS-SPSRSTREARSPQPNKRHSPSPRPRAPQTSS 695

Query: 76  GPGHYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHASSRQ-WKVSPPREEAARRG 134
            P     P  RG  + P+    R  SP   ++  + ++     ++  K + P  ++ RR 
Sbjct: 696 SP----PPVRRGASSSPQ----RRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRV 747

Query: 135 SESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNPQGARVPRR 192
           S S+S       A+  P A  +  +  Q    N    +    P  K ++P  +  P R
Sbjct: 748 SSSRSVSGSPEPAAKKPPAPPS-PVQSQSPSTNWSPAV----PVKKAKSPTPSPSPPR 800



 Score = 36.6 bits (83), Expect = 0.064
 Identities = 85/420 (20%), Positives = 141/420 (33%), Gaps = 79/420 (18%)

Query: 15  AQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSLQ 74
           A +  +V  + S +   G + A+            +++S +   ++  S  + P+   ++
Sbjct: 454 APKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVK 513

Query: 75  SG---------PGHYAVPTPRGT--ETGPRTESSRHSSPH-LKSQKTQTLASHASSRQWK 122
           +G         P   A P+PR    ET PR    R  SP   + +++ + A     R+  
Sbjct: 514 NGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTP 573

Query: 123 VSPPREEAARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQ 182
             PPR    RR       R         P  +  +  S   ++           PP   +
Sbjct: 574 TPPPR----RRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASP------PPPPKR 623

Query: 183 NPQGARVPRRILSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRR 242
               +  P+R +S+         P QR +  ++ RSP   S    GSS       T + R
Sbjct: 624 RASPSPPPKRRVSH------SPPPKQRSSPVTKRRSPSLSSKHRKGSS---PSRSTREAR 674

Query: 243 VPVEESETGPYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYSAY 302
            P       P  P P  P+                   S    R  A   P+   + S  
Sbjct: 675 SPQPNKRHSP-SPRPRAPQT----------------SSSPPPVRRGASSSPQ--RRQSPS 715

Query: 303 PETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSEGSHKS 362
           P T+P                         RRV+ +P  + ++     +  SV   S   
Sbjct: 716 PSTRPI------------------------RRVSRTPEPKKIKKAASPSPQSVRRVSSSR 751

Query: 363 SMFVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKPSIHAELELTPRPLPPRSLPRYG 422
           S+  +PEP  K+    P  +   SQ P+  +   S    +      TP P PPR+  + G
Sbjct: 752 SVSGSPEPAAKKPPAPPSPV--QSQSPSTNW---SPAVPVKKAKSPTPSPSPPRNSDQEG 806


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 51/169 (30%), Positives = 72/169 (42%), Gaps = 18/169 (10%)

Query: 351 TVPSVSEG-SHKSSMFVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKPSIHAELELT 409
           T+ SV+E  +   S F  PEP     T +P  +    QG        S +P     L+  
Sbjct: 357 TIRSVAEQHTPVCSRFSPPEP-GDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCE 415

Query: 410 PRPLPPRSL---PRY-GPDSSWWPLLNPEVETPQSQLTTPDFEPKCSPSLDLLLSG--FK 463
            +PL    +   P+   P +   PLL P  E+P S    P+  P   P     LS    +
Sbjct: 416 AKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSP--PPEESPTSPPPEASRLSPPPEE 473

Query: 464 IDSSPFCEDLKFQR--EKASLSPP------SPPKEFPSWAPLSEVPQTP 504
           + +SP  E L   R  E++ LSPP      SPP E   ++PL E P +P
Sbjct: 474 LPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSP 522



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 90/403 (22%), Positives = 143/403 (35%), Gaps = 59/403 (14%)

Query: 83  PTPRGTETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVS---PPREEAARRGSESKS 139
           P P    T P  E+SR S P  +S  +        S   + S   PP EE+       +S
Sbjct: 556 PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEES 615

Query: 140 GREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNPQGARVPRRILSYPKD 199
                  AS +        +S   +++ +        PP +V       V  R LS P +
Sbjct: 616 PLSPPPEASRLSPPPEDSPMSPPPEESPMS-------PPPEVSRLSPLPVVSR-LSPPPE 667

Query: 200 EAVQTEPIQRITTTSEIRSPR-------SPSLLEHGSSCVSADYQTAQRRVPVEESETGP 252
           E+  + P +   T+    + R       SP+      S  S   + +   +P+EES   P
Sbjct: 668 ESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEES---P 724

Query: 253 YGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYSAYPETKPSAKVL 312
             P+P +P+   R               S+G H +S R +   L      P   P A+  
Sbjct: 725 LLPLPEEPQLCPR---------------SEGPH-LSPRPEEPHLSPRPEEPHLSPQAEEP 768

Query: 313 -VSSQVESNVRTPIRGNSEVGRRVT---ISPGVQSVEPTHHVTVPSVSEGSHKSSMFVTP 368
            +S Q E      +     +  +     +SP  + +  +     P +S    +  +   P
Sbjct: 769 HLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQP 828

Query: 369 EPIY-KQQTQKP-----PEITYMSQGPTPRYPELSQKPS----------IHAELELTPRP 412
           E  +   Q+++P     PE +++S  P    P LS +P              EL L P P
Sbjct: 829 EESHLSPQSEEPCLSPRPEESHLS--PELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPP 886

Query: 413 LPPRSLPRYGPDSSWWPLLNPEVETPQSQLTTPDFEPKCSPSL 455
             P   P  G  +   P   P    P+    +P  EP  SP L
Sbjct: 887 GEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL 929



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 35/132 (26%), Positives = 54/132 (40%), Gaps = 16/132 (12%)

Query: 377  QKPPEITYMSQGPTPRYPELSQKPSI---HAELELTPRPLPPRSLPRYGPDSSWWPLLNP 433
            Q+PP    ++  P P +P++ +  S    +A+  LTPRP PP       P  S   L  P
Sbjct: 2350 QEPPPAQALAPSP-PSHPDIFRPGSYTDPYAQPPLTPRPQPP-------PPESCCAL--P 2399

Query: 434  EVETPQSQLTTPDFEPKCSPSLDLLLSGFKIDSSPFCEDL---KFQREKASLSPPSPPKE 490
                P    +     P+   S    L+   + +  FC      +FQ       PPS P+ 
Sbjct: 2400 PRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQS 2459

Query: 491  FPSWAPLSEVPQ 502
               +APL + P+
Sbjct: 2460 RDPFAPLHKPPR 2471



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 101/438 (23%), Positives = 143/438 (32%), Gaps = 67/438 (15%)

Query: 83  PTPRGTETGPRTESSRHSSPHLK---SQKTQTLASHASSRQWKVSPPREEAARRGSESKS 139
           P P  + T P  E+SR S P  +   S   + L       +  +SPP EE+         
Sbjct: 451 PPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEES--------- 501

Query: 140 GREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNPQGARVPRRILSYPKD 199
                      P +       F   + +  S   E  P   ++ P         LS P +
Sbjct: 502 -----------PLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE 550

Query: 200 EAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRVPVEESETGPYGPIPSK 259
           E+  + P + + T+    + R           +S   + +    P EES   P  P  S+
Sbjct: 551 ESPLSPPPEELPTSPPPEASR-----------LSPPPEESPMSPPPEESPMSP-PPEASR 598

Query: 260 PKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYSAYPETKPSAKVLVSSQVES 319
               +    L    + S L       R+S    P      S  PE  P     +S   E 
Sbjct: 599 LFPPFEESPLSPPPEESPLSPPPEASRLS---PPPEDSPMSPPPEESP-----MSPPPEV 650

Query: 320 NVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSEGSHKSSMFVTPEPIYKQQTQKP 379
           +  +P+   S +      SP     E +     P  S  S       T  P        P
Sbjct: 651 SRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPP 710

Query: 380 PEITYMS----QGPTPRYPELSQKPSIHAELELTPRPLPPRSLPRYGPDSSWWPLLNPEV 435
           PE + MS    + P    PE  Q         L+PRP  P   PR  P+    P L+P+ 
Sbjct: 711 PEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPR--PEE---PHLSPQA 765

Query: 436 ETPQSQLTTPDFEPKC------SPSLDLLLSGFKIDSSPFCEDLKFQREKASLSPP---- 485
           E P     +P  E  C       P L     G  +   P    L  Q E+  LSP     
Sbjct: 766 EEPH---LSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEP 822

Query: 486 --SPPKEFPSWAPLSEVP 501
             SP  E    +P SE P
Sbjct: 823 CLSPQPEESHLSPQSEEP 840



 Score = 30.0 bits (66), Expect = 6.0
 Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 3/66 (4%)

Query: 352  VPSVSEGSHKSSMFVTPEPIYKQQTQKPPEITYMSQGPTP--RYPELSQKPSIHAELELT 409
            VP+  +    S   +TP P+   +   P  +T   Q P P  R P   Q     A L   
Sbjct: 2411 VPASPQSQSSSQSPLTPRPL-SAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKP 2469

Query: 410  PRPLPP 415
            PRP PP
Sbjct: 2470 PRPQPP 2475


>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
          Length = 1984

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 87/355 (24%), Positives = 130/355 (36%), Gaps = 30/355 (8%)

Query: 19   SEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSLQSGPG 78
            SE +  +S ++ H      SH S +   + S        P+  +  S   RS    S  G
Sbjct: 1570 SERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERG 1629

Query: 79   HYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSESK 138
             ++ P+ R +  GP     RH SP  +S ++ +  SH SS + +   P + + R  SE  
Sbjct: 1630 LHS-PSQR-SHRGP--SQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSER- 1684

Query: 139  SGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNPQGARVPRRILS--- 195
                  H + S    +S  Q S +               PSK  +   AR   R  S   
Sbjct: 1685 -----SHCSPSERRHRSPSQRSHRGPSER------RHHSPSKRSHRSPARRSHRSPSERS 1733

Query: 196  -YPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRR--VPVEESETGP 252
             +   E     P +R   +   RS  SPS   H S         ++RR   P E+S   P
Sbjct: 1734 HHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSP 1793

Query: 253  YGPIPSKPKALYRNMNLD----SLLKLSVLKDSDGVHRVSARVDPESLHKYSAYPETKPS 308
                   P    R+  L+    SLL+ S    S+     S       + + S  P  K  
Sbjct: 1794 SERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSH 1853

Query: 309  AKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSEGSHKSS 363
               L  S+   + R   RG+S  G +   SP  +S      +     SE SH+SS
Sbjct: 1854 LSPLERSRCSPSER---RGHSSSG-KTCHSPSERSHRSPSGMRQGRTSERSHRSS 1904


>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
          Length = 861

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 99/462 (21%), Positives = 149/462 (32%), Gaps = 106/462 (22%)

Query: 14  SAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSL 73
           +   G   T  + P         S   SA V L+ ++  S ++ PTT  SAS      S 
Sbjct: 268 TTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSE 327

Query: 74  QSGPGHYA------VPTPRGTETGPRTESSR--HSSP------HLKSQKT------QTLA 113
           +S P H +       P P  + T    E S   H SP      H     T      ++  
Sbjct: 328 ESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESAT 387

Query: 114 SHASSRQWKVSPPREEAAR-----------------RGSESKSGREVGHHAS-SIPDAKS 155
            H S+   K S P   AA                  R S + SGR     AS S PDA +
Sbjct: 388 FHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMA 447

Query: 156 THQLSFQDQKNNLQSQILEDDPPSKV------------------------------QNPQ 185
           T  L       +  S ++ D  PS +                              ++P 
Sbjct: 448 TTVL----PAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPD 503

Query: 186 GARVPRRILSYPKDEAVQTEPIQ--RITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRV 243
              +P R+ S    E   T   +     TT+   S   P L +  ++  S+   T     
Sbjct: 504 TTHLPARMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLS 563

Query: 244 P--VEESETGP-YGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVH--------------R 286
           P     S  GP Y    S P +    +  D+     +L+ S  VH               
Sbjct: 564 PGSTTASSLGPEYTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTRSPHTTLSPAGS 623

Query: 287 VSARVDPESLHKYSAYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEP 346
            + + +  + H + +  +T+P+     S+ VE +               T S G  S  P
Sbjct: 624 TTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPS---------------TTSHGSPSSIP 668

Query: 347 THHVTVPSVSEGSHKSSMFVTPEPIYKQQTQKPPEITYMSQG 388
           T H++  S + G  + S      P   Q    P   T   +G
Sbjct: 669 TTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRG 710


>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
          Length = 1240

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 63/249 (25%), Positives = 80/249 (32%), Gaps = 38/249 (15%)

Query: 269 LDSLLKLSVLKDSDGVHRVSARVDPESLHKYSAYPETKPSAKVLVSSQVESNVRTPIRGN 328
           L+SL+  +VL  SD        V    L   S     +PS  V     V++N+    RG+
Sbjct: 315 LESLVNRAVLLASDAQECTLEEVVERLL---SVKGRPRPSPLVKAHKSVQANLDQSQRGS 371

Query: 329 SEVGRRVTISPGVQSVEPTHHVTVPSVSEGSHKSSMFVTPEPIYKQQTQKPPEITYMSQG 388
           S      T  P V+  +P        V     +S + V+     +QQ   PP        
Sbjct: 372 SPQNT-TTPKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPP-----PPP 425

Query: 389 PTPRYPELSQKPSIHAELELTPRPLPPRSLPRYGPDSSWWPLLNPEVETPQSQLTTPDFE 448
           P P  P  S +P         P P PP  LP  G  +   P   P    P      P   
Sbjct: 426 PPPLLPGSSAEP---------PPPPPPPPLPSVGAKA--LPTAPPPPPLPGLGAMAPPAP 474

Query: 449 PKCSPSLDLLLSG---FKIDSSPFCEDLKFQREKASLSPPSPPKEFP--SWAPLSEVPQT 503
           P   P     L G   F     P    L          PP PP   P   W P    P  
Sbjct: 475 PLPPP-----LPGSCEFLPPPPPPLPGLG--------CPPPPPPLLPGMGWGPPPPPPPL 521

Query: 504 PKHTCKQPI 512
              TC  P+
Sbjct: 522 LPCTCSPPV 530


>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
          Length = 1249

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 63/249 (25%), Positives = 80/249 (32%), Gaps = 38/249 (15%)

Query: 269 LDSLLKLSVLKDSDGVHRVSARVDPESLHKYSAYPETKPSAKVLVSSQVESNVRTPIRGN 328
           L+SL+  +VL  SD        V    L   S     +PS  V     V++N+    RG+
Sbjct: 315 LESLVNRAVLLASDAQECTLEEVVERLL---SVKGRPRPSPLVKAHKSVQANLDQSQRGS 371

Query: 329 SEVGRRVTISPGVQSVEPTHHVTVPSVSEGSHKSSMFVTPEPIYKQQTQKPPEITYMSQG 388
           S      T  P V+  +P        V     +S + V+     +QQ   PP        
Sbjct: 372 SPQNT-TTPKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPP-----PPP 425

Query: 389 PTPRYPELSQKPSIHAELELTPRPLPPRSLPRYGPDSSWWPLLNPEVETPQSQLTTPDFE 448
           P P  P  S +P         P P PP  LP  G  +   P   P    P      P   
Sbjct: 426 PPPLLPGSSAEP---------PPPPPPPPLPSVGAKA--LPTAPPPPPLPGLGAMAPPAP 474

Query: 449 PKCSPSLDLLLSG---FKIDSSPFCEDLKFQREKASLSPPSPPKEFP--SWAPLSEVPQT 503
           P   P     L G   F     P    L          PP PP   P   W P    P  
Sbjct: 475 PLPPP-----LPGSCEFLPPPPPPLPGLG--------CPPPPPPLLPGMGWGPPPPPPPL 521

Query: 504 PKHTCKQPI 512
              TC  P+
Sbjct: 522 LPCTCSPPV 530


>gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial
           [Homo sapiens]
          Length = 909

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 103/513 (20%), Positives = 164/513 (31%), Gaps = 89/513 (17%)

Query: 19  SEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSLQSGPG 78
           S  TT T+      +  + S         PS         TT HS   Y  S++    P 
Sbjct: 34  SITTTETTSHSTPSFTSSISTTETTSHSTPSFTSLITITETTSHSTPSYTTSITTTETPS 93

Query: 79  HYAVPTPRGTETGPRTESSRHSSPHLKSQKTQT-LASHASSRQWKVSPPREEAARRGSES 137
           H    TP  T +   TE+  HS+P   S  T T   SH        S P   ++ R +E+
Sbjct: 94  H---STPSYTTSITTTETPSHSTPSFTSSITTTETTSH--------STPSFTSSIRTTET 142

Query: 138 KSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNPQGARVPRRILSYP 197
            S     +   S   + +  + +     + + S    + P S   +   +       S+ 
Sbjct: 143 TS-----YSTPSFTSSNTITETTSHSTPSYITSITTTETPSSSTPSFSSSITTTETTSH- 196

Query: 198 KDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRVPVEESETGPYGPIP 257
                 T       TT+E  S  +PS     ++  +  + T      +  SET    P  
Sbjct: 197 -----STPGFTSSITTTETTSHSTPSFTSSITTTETTSHDTPSFTSSITTSET----PSH 247

Query: 258 SKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYSAYPETKPSAKVLVSSQV 317
           S P +        SL+  +         + ++   P      +    T  SA    SS  
Sbjct: 248 STPSS-------TSLITTT---------KTTSHSTPSFTSSITTTETTSHSAHSFTSS-- 289

Query: 318 ESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVT------VPSVSEGSHKSSMFVTPEPI 371
                                  + + E T H T      + +    SH ++ F +   I
Sbjct: 290 -----------------------ITTTETTSHNTRSFTSSITTTETNSHSTTSFTS--SI 324

Query: 372 YKQQTQKPPEITYMSQGPTPRYPELSQKPSIHAELELTPRPLPPRSLPRYGPDSSWWPLL 431
              +T      ++ S   T          +  +E  +TP P+ P SL    P +S   L 
Sbjct: 325 TTTETTSHSTPSFSSSITTTETXXXXXXXT--SETAVTPTPVTPSSLSTDIPTTSLRTLT 382

Query: 432 NPEVETPQSQLTTPDFEPKCSPSLDLLLSGFKIDSSPFCEDLKFQREKASLSPPSPPKEF 491
              V T  S  TT DF    +    L      I SSP  +  +      + SP       
Sbjct: 383 PSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQSTETSSLVGTTSP------- 435

Query: 492 PSWAPLSEVPQTPKHTCKQPIQRFTAFFLDVSE 524
                +S V  T + T   PI  F+   + + E
Sbjct: 436 ----TMSTVRMTLRITENTPISSFSTSIVVIPE 464


>gi|148612879 polyhomeotic like 3 [Homo sapiens]
          Length = 995

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 83/364 (22%), Positives = 144/364 (39%), Gaps = 64/364 (17%)

Query: 88  TETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSESKSGREVGHHA 147
           ++ GP   +S+  S  +   KT   +S  S R      P  E+ ++G ES S   +   +
Sbjct: 241 SQNGPPKSTSQTQSLTICHNKTTVTSSKISQRD-----PSPESNKKG-ESPS---LESRS 291

Query: 148 SSIPDAKSTHQLSFQDQKNNLQ-------SQILEDDPPSKVQNPQGARVPRRILSYPKDE 200
           +++    S HQL      + +Q        QI    PPSKV + Q       IL      
Sbjct: 292 TAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQ------LILQQ---- 341

Query: 201 AVQTEPIQRITTTSEIRSPRSPS-----LLEHGSSCVSADYQTAQRRVPVEESETGPYGP 255
             Q + IQ IT  +  + P  PS     L  HG     ++ Q+ Q   P++ S   P   
Sbjct: 342 --QQQQIQPITLQNSTQDP-PPSQHCIPLQNHGLPPAPSNAQS-QHCSPIQ-SHPSPLTV 396

Query: 256 IPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYSAYPETKPSAKVLVSS 315
            P++ ++  +++ +      S  +    +    A + P  L   +  P   P+ +   ++
Sbjct: 397 SPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPG--PNLQQSTAN 454

Query: 316 QVESNVR-----------TPIRGNSEVGRRVTISPGVQSVEPTHH---------VTVPSV 355
           QV++  +           +P+     V +   +SPG Q V P+H          + + S 
Sbjct: 455 QVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASP 514

Query: 356 SEGSHKSSMFVTPEPIYKQQT-QKPPEITYMSQGPTPRYPEL---SQKPSIHAELELTPR 411
            + S      + P P+   Q+ Q  PEI  +SQG       L    + P+  A ++L  +
Sbjct: 515 PQMSTSPPAQIPPLPLQSMQSLQVQPEI--LSQGQVLVQNALVSEEELPAAEALVQLPFQ 572

Query: 412 PLPP 415
            LPP
Sbjct: 573 TLPP 576



 Score = 36.2 bits (82), Expect = 0.083
 Identities = 46/225 (20%), Positives = 88/225 (39%), Gaps = 35/225 (15%)

Query: 210 ITTTSEIRSPRSPSLLE-----HGSSCVSADYQTAQRRVPVEESETGPYGPIPSKPKALY 264
           + ++S+   P+S S  +     H  + V++  + +QR    E ++ G    + S+  A+ 
Sbjct: 237 VLSSSQNGPPKSTSQTQSLTICHNKTTVTSS-KISQRDPSPESNKKGESPSLESRSTAVT 295

Query: 265 RNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYSAYPETKPSAKVLVSSQVESNVRTP 324
           R  ++  L+  +              + P SL K+   P   P +KV       S+ +  
Sbjct: 296 RTSSIHQLIAPASYSP----------IQPHSLIKHQQIPLHSPPSKV-------SHHQLI 338

Query: 325 IRGNSEVGRRVTISPGVQSVEPTHHVT---------VPSVSEGSHKSSMFVTPEP--IYK 373
           ++   +  + +T+    Q   P+ H            PS ++  H S +   P P  +  
Sbjct: 339 LQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSP 398

Query: 374 QQTQKPPEITYMSQGPTPRYPELSQKPSIHAELELTPRPLPPRSL 418
            Q+Q   +   +S  P P  P  S    IH +  + P PL   +L
Sbjct: 399 NQSQSAQQSVVVSP-PPPHSPSQSPTIIIHPQALIQPHPLVSSAL 442


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 53/229 (23%), Positives = 88/229 (38%), Gaps = 27/229 (11%)

Query: 122  KVSPPREEAARRGSESKSGREVGHHASSIPDAKSTHQL-------SFQDQKNNLQSQILE 174
            + S  + E  +  SE   G + G     +P  K+T  L       S +D+   LQ ++ E
Sbjct: 1720 QASAEKAELKKGSSEESLGEDPGLAPEPLPTVKATSPLIEETPIGSIKDKVKALQKRV-E 1778

Query: 175  DDPPSKVQNPQGARVPRRILSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSA 234
            D+   + + P   +    +   PK    +  P    +  SE  +P SPS      S +S+
Sbjct: 1779 DEQKGRSKLPIRVKGKEDV---PKKTTHRPHPAASPSLKSERHAPGSPSPKTERHSTLSS 1835

Query: 235  DYQTAQRRVPVE-ESETGPYGPIPSKPKALYRN--MNLDSLLKLSVLKDSDGVHRVSARV 291
              +T +R  PV   S+T  + P+    K    +   +     K S +  S    R S   
Sbjct: 1836 SAKT-ERHPPVSPSSKTEKHSPVSPSAKTERHSPASSSSKTEKHSPVSPSTKTERHS--- 1891

Query: 292  DPESLHKYSAYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPG 340
             P S  K   +P   PS K        ++ R P+  +    +   +SPG
Sbjct: 1892 -PVSSTKTERHPPVSPSGK--------TDKRPPVSPSGRTEKHPPVSPG 1931


>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
          Length = 1512

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 88/418 (21%), Positives = 153/418 (36%), Gaps = 71/418 (16%)

Query: 53  SEAAHPTTPHSASDYPRSVSLQSGPGHYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTL 112
           SEA+   + HS S   R+   +SG           + +G R +S+  +S    S+K +  
Sbjct: 226 SEASKSRSRHSHSGEERAEVAKSGSS---------SSSGGRRKSASATSSSSSSRKDRDS 276

Query: 113 ASHASSRQWKVSPPR--EEAARRGSESKSGREVGHHASSIP------DAKSTHQLSFQDQ 164
            +H S  +    PP   +E  +   E K+  +      S+       D+  +H+ S    
Sbjct: 277 KAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRAS---- 332

Query: 165 KNNLQSQILEDDPPSKVQNPQGARVPR--------------RILSYPKDEAVQTEPIQRI 210
             +L+S+     P     +P   R+PR              R  SY +   V   P    
Sbjct: 333 -QSLRSR-KSPSPAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSS- 389

Query: 211 TTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRVPVEESETGPYGPIPSKPKALYRNMNLD 270
           ++    RSP SP L   G S   + Y +   R               S+ ++ + +++  
Sbjct: 390 SSWRRSRSPYSPVLRRSGKSRSRSPYSSRHSRSRSRHRL--------SRSRSRHSSISPS 441

Query: 271 SLLKLSVLKDSDGVHRVSARVDPESLHKYSAYPETKPSAKVLVSSQVESNVRTPIRGNSE 330
           +L   S L      ++ +   +     + +   E   +A+    +   SN  TP +GN+E
Sbjct: 442 TLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAAKASNTSTPTKGNTE 501

Query: 331 VGRRVTISPGVQSVE--PTHHVTVPSVSEGSHKSSMFVTPEP----------IYKQQTQK 378
                + +  V+ V+     H   PS S G+ K+    T  P          I  + T+K
Sbjct: 502 TSASASQTNHVKDVKKIKIEHAPSPS-SGGTLKNDKAKTKPPLQVTKVENNLIVDKATKK 560

Query: 379 PPEITYMSQGPTPRYPELSQK-------PSIHAE-----LELTPRPLPPRSLPRYGPD 424
              +   S+    +   +S K       PSI A+     + L    LPP  LP   P+
Sbjct: 561 AVIVGKESKSAATKEESVSLKEKTKPLTPSIGAKEKEQHVALVTSTLPPLPLPPMLPE 618


>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
          Length = 1452

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 88/418 (21%), Positives = 153/418 (36%), Gaps = 71/418 (16%)

Query: 53  SEAAHPTTPHSASDYPRSVSLQSGPGHYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTL 112
           SEA+   + HS S   R+   +SG           + +G R +S+  +S    S+K +  
Sbjct: 226 SEASKSRSRHSHSGEERAEVAKSGSS---------SSSGGRRKSASATSSSSSSRKDRDS 276

Query: 113 ASHASSRQWKVSPPR--EEAARRGSESKSGREVGHHASSIP------DAKSTHQLSFQDQ 164
            +H S  +    PP   +E  +   E K+  +      S+       D+  +H+ S    
Sbjct: 277 KAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRAS---- 332

Query: 165 KNNLQSQILEDDPPSKVQNPQGARVPR--------------RILSYPKDEAVQTEPIQRI 210
             +L+S+     P     +P   R+PR              R  SY +   V   P    
Sbjct: 333 -QSLRSR-KSPSPAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSS- 389

Query: 211 TTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRVPVEESETGPYGPIPSKPKALYRNMNLD 270
           ++    RSP SP L   G S   + Y +   R               S+ ++ + +++  
Sbjct: 390 SSWRRSRSPYSPVLRRSGKSRSRSPYSSRHSRSRSRHRL--------SRSRSRHSSISPS 441

Query: 271 SLLKLSVLKDSDGVHRVSARVDPESLHKYSAYPETKPSAKVLVSSQVESNVRTPIRGNSE 330
           +L   S L      ++ +   +     + +   E   +A+    +   SN  TP +GN+E
Sbjct: 442 TLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAAKASNTSTPTKGNTE 501

Query: 331 VGRRVTISPGVQSVE--PTHHVTVPSVSEGSHKSSMFVTPEP----------IYKQQTQK 378
                + +  V+ V+     H   PS S G+ K+    T  P          I  + T+K
Sbjct: 502 TSASASQTNHVKDVKKIKIEHAPSPS-SGGTLKNDKAKTKPPLQVTKVENNLIVDKATKK 560

Query: 379 PPEITYMSQGPTPRYPELSQK-------PSIHAE-----LELTPRPLPPRSLPRYGPD 424
              +   S+    +   +S K       PSI A+     + L    LPP  LP   P+
Sbjct: 561 AVIVGKESKSAATKEESVSLKEKTKPLTPSIGAKEKEQHVALVTSTLPPLPLPPMLPE 618


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 39.3 bits (90), Expect = 0.010
 Identities = 76/281 (27%), Positives = 100/281 (35%), Gaps = 58/281 (20%)

Query: 7   PGAKVAVSAQ-RGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSAS 65
           P  + A S+Q RG         ++        S  SA+       RR   A P     + 
Sbjct: 364 PSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSL 423

Query: 66  DYPRSVSLQSGPGHYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSP 125
              RS S  SG G  A P P     GP   S R    H K  K +   +  +S     SP
Sbjct: 424 SRARSSS-DSGSGRGA-PGP-----GPEPGSERGHGGHGKRAKERPPRARPAS----TSP 472

Query: 126 -PREEAARRGSESKSG-REVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQN 183
            P     R G E KS  R  G H  S   ++S          +  +S+  E  P S  ++
Sbjct: 473 SPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSP---------SKSRSRSAEKRPHSPSRS 523

Query: 184 PQGARVPRRILSYPKD--------EAVQTEPIQRITTTSEIRSPR--SPSLLE------- 226
           P     P++ LS  KD        EA  T   +R  + S IR  R  SPS +E       
Sbjct: 524 PS----PKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSA 579

Query: 227 -------------HGSSCVSADYQT-AQRRVPVEESETGPY 253
                          SSC+S+DY T +  R P      G Y
Sbjct: 580 RKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSY 620


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 38.9 bits (89), Expect = 0.013
 Identities = 105/464 (22%), Positives = 148/464 (31%), Gaps = 66/464 (14%)

Query: 14  SAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSL 73
           +   G   T  + P         S   SA V L+ ++  S ++ PTT  SAS      S 
Sbjct: 333 TTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSE 392

Query: 74  QSGPGHYA------VPTPRGTETGPRTESSR--HSSP------HLKSQKT------QTLA 113
           +S P H +       P P  + T    E S   H SP      H     T      ++  
Sbjct: 393 ESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESAT 452

Query: 114 SHASSRQWKVSPPREEAAR-----------------RGSESKSGREVGHHAS-SIPDAKS 155
            H S+   K S P   AA                  R S + SGR     AS S PDA +
Sbjct: 453 FHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMA 512

Query: 156 THQLSFQDQKNNLQSQILEDDPPSKVQNPQGARVPRRILSYPKDEAVQTEPIQRITTTSE 215
           T  L       +  S ++ D  PS + +          +         T+P     +T+ 
Sbjct: 513 TTVL----PAGSTPSVLVGDSTPSPISSGS--------METTALPGSTTKPGLSEKSTTF 560

Query: 216 IRSPRSPSLLEHGSSCVSADYQTAQRRVPVEESETGPYGPIPSKPKALYRNMNLDSLLKL 275
             SPRSP      +S  S+           EES T    P  +   A   +  +  L + 
Sbjct: 561 YSSPRSPDTTHLPASMTSSGVS--------EESTTSHSRPGSTHTTAFPGSTTMPGLSQE 612

Query: 276 SVLKDSDGVHRVSARVDPESLHKYSAYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRV 335
           S    S         + P S    S  PE          S+  S   T +  N+     +
Sbjct: 613 STASHS-SPGPTDTTLSPGSTTASSLGPE-----YTTFHSRPGSTETTLLPDNTTASGLL 666

Query: 336 TISPGVQSVEPTHHVTV-PSVSEGSHKSSMFVTPEPIYKQQTQKPPEITYMSQGP-TPRY 393
             S  V S   + H T+ P+ S      S      P        PP  T     P T  +
Sbjct: 667 EASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSH 726

Query: 394 PELSQKPSIHAELELTPRPLPPRSLPRYGPDSSWWPLLNPEVET 437
              S  P+ H     T   L   S   +    S   +  PE +T
Sbjct: 727 GSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDT 770



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 93/437 (21%), Positives = 152/437 (34%), Gaps = 58/437 (13%)

Query: 14   SAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASD-----YP 68
            + ++G   T  + P          +  SA V L+ +   S ++ PTT  SAS        
Sbjct: 1130 TTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSE 1189

Query: 69   RSVSLQSGP-GHYAVPTP-RGTETGPRTESSR-HSSP------HLKSQKT------QTLA 113
             S ++ S P      P+P R T +G   ES+  HSSP      H     T      ++  
Sbjct: 1190 ESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 1249

Query: 114  SHASSRQWKVSPPREEAARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQIL 173
            SH+S+     SPP   +A     +      G  A++     ST     ++   +  S   
Sbjct: 1250 SHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDT 1309

Query: 174  EDDPPSKVQNPQGARVPRRILSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVS 233
                P         R+      Y    +++T      TT         P L    +   S
Sbjct: 1310 NGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATT---------PGLSAKSTILYS 1360

Query: 234  ADYQTAQRRVPVEESETGPYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDP 293
            +     Q   P   + +     I  +P +LY                + G+ + S     
Sbjct: 1361 SSRSPDQTLSPASMTSSS----ISGEPTSLYSQAESTHTTAFPASTTTSGLSQEST---- 1412

Query: 294  ESLHKYSAYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRV-TISPGVQSV-----EPT 347
             + H      ET  S   + +S       TP   +S+ G  + T+SP   +V     E T
Sbjct: 1413 -TFHSKPGSTETTLSPGSITTSSFAQEFTTP---HSQPGSALSTVSPASTTVPGLSEEST 1468

Query: 348  HHVTVPSVSEG---SHKSSMFVTPEPIYKQQTQKP--PEITYMSQGPTPRYPELSQK-PS 401
               + P  +E    SH ++M +  +    Q T  P  P  T+     T    ++ Q+  +
Sbjct: 1469 TFYSSPGSTETTAFSHSNTMSIHSQ----QSTPFPDSPGFTHTVLPATLTTTDIGQESTA 1524

Query: 402  IHAELELT-PRPLPPRS 417
             H+  + T   PLP RS
Sbjct: 1525 FHSSSDATGTTPLPARS 1541


>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 2 [Homo sapiens]
          Length = 1320

 Score = 38.9 bits (89), Expect = 0.013
 Identities = 52/218 (23%), Positives = 78/218 (35%), Gaps = 33/218 (15%)

Query: 44  VSLNPSHRRSEAAH---PTTPHSASDYPRSVSLQSGPGHYAVPTPRGTETGPRTESSRHS 100
           +SL   HRR    H   P  P      P S        HY  P  R  E   R   + HS
Sbjct: 522 LSLQHDHRRPHPQHSQQPPPPQQERSKP-SFHAPEPKAHYE-PADRAREVEDRFRKTNHS 579

Query: 101 SPHLKSQKT-QTLASHASSRQWKVSPPREEAARRGSESKSGREV---------------- 143
           SP  +S++T + L     SR    S    E+     +  +  +V                
Sbjct: 580 SPEAQSKQTGRVLEPPVPSRSESFSNGNSESVHPALQRPAEPQVQWSHLASLKNNVSPVS 639

Query: 144 GHHASSIPDAK-STHQLSFQDQKNNLQSQILEDDPPSKVQNPQGARVPRRILSYPKDEAV 202
             H+ S P  K + H L  QD     +S++L     SK + P   +      ++ + ++ 
Sbjct: 640 RSHSFSDPSPKFAHHHLRSQDPCPPSRSEVLSQSSDSKSEAPDPTQ-----KAWSRSDSD 694

Query: 203 QTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQ 240
           +  P   + TTS     RSP L    S    +  Q +Q
Sbjct: 695 EVPPRVPVRTTS-----RSPVLSRRDSPLQGSGQQNSQ 727



 Score = 30.0 bits (66), Expect = 6.0
 Identities = 86/399 (21%), Positives = 145/399 (36%), Gaps = 43/399 (10%)

Query: 13  VSAQRGSEVTTNTSPQQGHGYVLASS----HRSAAVSLNPSHRRSEAAHPTTPHSASDYP 68
           VS    S   ++ SP+  H ++ +       RS  +S + S  +SEA  PT       + 
Sbjct: 635 VSPVSRSHSFSDPSPKFAHHHLRSQDPCPPSRSEVLSQS-SDSKSEAPDPTQ----KAWS 689

Query: 69  RSVSLQSGPGHYAVPTPRGT----ETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVS 124
           RS S +  P      T R         P   S + +S   +   T ++       + +  
Sbjct: 690 RSDSDEVPPRVPVRTTSRSPVLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKL 749

Query: 125 PPREEAARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNP 184
            PR  +      S SG + G H  S   +    ++    +     SQ LE    + V+ P
Sbjct: 750 VPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLE----NAVKKP 805

Query: 185 QGARVPRRILSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRVP 244
           +  +   R L  P  E   T   + +    ++R P   +     SS  S         V 
Sbjct: 806 EDKKEVFRPLK-PAGEVDLTALAKELRAVEDVRPPHKVTDYS-SSSEESGTTDEEDDDVE 863

Query: 245 VEESETGPYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYSAYPE 304
            E ++    GP  ++  +   ++NL +        +++ V  +    D ES       P 
Sbjct: 864 QEGADESTSGPEDTRAAS---SLNLSN-------GETESVKTMIVHDDVES------EPA 907

Query: 305 TKPSAK-VLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSEGSHKSS 363
             PS +  L+  Q +S   T  +  S       I P +  + P+   TV SV   S    
Sbjct: 908 MTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSCDG- 966

Query: 364 MFVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKPSI 402
             + PE I +  T+K    + ++  PT   P+ S  P I
Sbjct: 967 --MRPEAIRQDPTRKG---SVVNVNPTNTRPQ-SDTPEI 999


>gi|169218320 PREDICTED: similar to BCL2-associated transcription
           factor 1 isoform 2 [Homo sapiens]
          Length = 869

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 28/121 (23%), Positives = 44/121 (36%)

Query: 29  QGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSLQSGPGHYAVPTPRGT 88
           +G GY      R       P   R  +  P    S S  P+  S+ S            +
Sbjct: 74  RGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRS 133

Query: 89  ETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSESKSGREVGHHAS 148
              PR+ SSR SSP+ KS  ++   S     +     P+EE+  +    +  ++   H  
Sbjct: 134 SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDP 193

Query: 149 S 149
           S
Sbjct: 194 S 194


>gi|117938254 BCL2-associated transcription factor 1 isoform 3 [Homo
           sapiens]
          Length = 747

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 28/121 (23%), Positives = 44/121 (36%)

Query: 29  QGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSLQSGPGHYAVPTPRGT 88
           +G GY      R       P   R  +  P    S S  P+  S+ S            +
Sbjct: 76  RGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRS 135

Query: 89  ETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSESKSGREVGHHAS 148
              PR+ SSR SSP+ KS  ++   S     +     P+EE+  +    +  ++   H  
Sbjct: 136 SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDP 195

Query: 149 S 149
           S
Sbjct: 196 S 196


>gi|117938251 BCL2-associated transcription factor 1 isoform 2 [Homo
           sapiens]
          Length = 869

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 28/121 (23%), Positives = 44/121 (36%)

Query: 29  QGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSLQSGPGHYAVPTPRGT 88
           +G GY      R       P   R  +  P    S S  P+  S+ S            +
Sbjct: 74  RGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRS 133

Query: 89  ETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSESKSGREVGHHAS 148
              PR+ SSR SSP+ KS  ++   S     +     P+EE+  +    +  ++   H  
Sbjct: 134 SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDP 193

Query: 149 S 149
           S
Sbjct: 194 S 194


>gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Homo
           sapiens]
          Length = 920

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 28/121 (23%), Positives = 44/121 (36%)

Query: 29  QGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSLQSGPGHYAVPTPRGT 88
           +G GY      R       P   R  +  P    S S  P+  S+ S            +
Sbjct: 76  RGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRS 135

Query: 89  ETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSESKSGREVGHHAS 148
              PR+ SSR SSP+ KS  ++   S     +     P+EE+  +    +  ++   H  
Sbjct: 136 SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDP 195

Query: 149 S 149
           S
Sbjct: 196 S 196


>gi|239582741 FERM and PDZ domain containing 1 [Homo sapiens]
          Length = 1578

 Score = 38.1 bits (87), Expect = 0.022
 Identities = 45/185 (24%), Positives = 70/185 (37%), Gaps = 30/185 (16%)

Query: 305  TKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSEGSHKSSM 364
            + P+ K++ S  +++    P+ G  ++       P  QS EP      P     + +  +
Sbjct: 1151 SSPAGKIVTSLSLDA----PVTGTEQIPPHPPRDPQGQSREP------PGQGCQAQEQKL 1200

Query: 365  FVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKPSIHAELELTPRPLPPRSLPRYGPD 424
            FV        +    P+     Q  +P  P    K    A   +T + + PR       D
Sbjct: 1201 FV--------ELDLDPDFFLGKQTVSPAVPPEGIKAE--APNHVTGQDIAPR-------D 1243

Query: 425  SSWWPLLNPEVETPQSQLTTPDFEPKCSPSLDLLLSGFKIDSSPFCEDLKFQREKASLSP 484
            S  W   NPE   P+  L  P  +P    S   LLS  K DSS  C  L  ++     +P
Sbjct: 1244 SPEWVCFNPEPSLPEP-LPCPQEDPHLETSNHCLLSEGKSDSSSIC--LSAEKSFLCFAP 1300

Query: 485  PSPPK 489
             S P+
Sbjct: 1301 ESHPE 1305


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
           sapiens]
          Length = 2036

 Score = 38.1 bits (87), Expect = 0.022
 Identities = 87/416 (20%), Positives = 136/416 (32%), Gaps = 54/416 (12%)

Query: 3   KTNKPGAKVAVSAQRGSEVTTNTSPQQ-GHGYVLASSHRSAAVSLNPSHRRSEAAHPTTP 61
           K  +P      SA      T++ SP      ++ A S  S  V  + ++  S  +  T  
Sbjct: 271 KDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMH 330

Query: 62  HSASDYP-----RSVSLQSGPGHYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHA 116
              SD        S +  S   H     P  T       +S HSSP        T  +H 
Sbjct: 331 FPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPG------STATTHF 384

Query: 117 SSRQWKVSPPREEAARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDD 176
                      E  A   S+  +G  V      +P   +T  L  +   + + S  +E  
Sbjct: 385 PDSSTTSGRSEESTASHSSQDATGTIV------LPARSTTSVLLGESTTSPISSGSMETT 438

Query: 177 P-PSKVQNPQGARVPRRILSYPKDEAVQTEP-------IQRITTTSEIR----------- 217
             P     P  +       S P+  A    P       +   +TTS  R           
Sbjct: 439 ALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPD 498

Query: 218 SPRSPSLLEHGSSCVSADYQTAQRRVPVEESETGPYGPIPSKPKALYRNMNLDSLLKL-S 276
           S  +P L  H ++  S+   T    +P   + +GP     +   +   + + D+ L   S
Sbjct: 499 STTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS---SGSTDTALSPGS 555

Query: 277 VLKDSDGVHRVSARVDPESLHKYSAYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVT 336
               S G    +   +P S H       T  S  V  S++V S+  +P    + +    +
Sbjct: 556 TTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP---RTTLSPASS 612

Query: 337 ISPGVQSVEPTHHVTVPSVSEGSHKSSMFVTPEPIYKQQTQKPPEITY-MSQGPTP 391
            SPG+Q           S +  +H +S   TP P            TY  S G TP
Sbjct: 613 TSPGLQG---------ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 659



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 37/145 (25%), Positives = 59/145 (40%), Gaps = 10/145 (6%)

Query: 14   SAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSL 73
            + ++G   T  + P          +  SA V L+ +   S ++ PTT  SAS      S 
Sbjct: 1310 TTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSE 1369

Query: 74   QSGPGHYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHAS--SRQWKVSPPREEAA 131
            +S   H    +P  T T P    +R ++  L  + T   A H+S  S Q    P    A+
Sbjct: 1370 ESTTVH---SSPVATATTP--SPARSTTSGLVEEST---AYHSSPGSTQTMHFPESSTAS 1421

Query: 132  RRGSESKSGREVGHHASSIPDAKST 156
             R  ES++      H  S P + ++
Sbjct: 1422 GRSEESRTSHSSTTHTISSPPSTTS 1446


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 38.1 bits (87), Expect = 0.022
 Identities = 46/194 (23%), Positives = 74/194 (38%), Gaps = 10/194 (5%)

Query: 62   HSASDYPRSVSLQSG--PGHYAVPTPRGTETGPRTESSRHSSPH-LKSQKTQTLASHASS 118
            H   D+ R     +G  PG  A   P   + G R E+  HS P    +   +    + SS
Sbjct: 3645 HRHGDHGRHSGRHTGEEPGRRAAK-PHARDLG-RHEARPHSQPSSAPAMPKKGQPGYPSS 3702

Query: 119  RQWKVSPPREEAARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPP 178
             ++        A    S+SK G    H   +   +K+  Q   Q Q         +   P
Sbjct: 3703 AEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSP 3762

Query: 179  SKVQNPQGARVPRRILSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQT 238
            S  Q P GA   R+  +  + + +  +P Q+  T + ++    P+    GS+   A  Q 
Sbjct: 3763 SSRQIPSGA-ASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPT--TRGSA--PAASQP 3817

Query: 239  AQRRVPVEESETGP 252
            A +  P   + TGP
Sbjct: 3818 AGKPQPGPSTATGP 3831



 Score = 30.0 bits (66), Expect = 6.0
 Identities = 98/453 (21%), Positives = 147/453 (32%), Gaps = 87/453 (19%)

Query: 5    NKPGAKVAVSAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLN--------PSHRRSEAA 56
            N   A +    Q G  +T  TSP Q    V  S+  S+  S            H   E  
Sbjct: 1292 NAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQ 1351

Query: 57   HPTTPHSASDYPRSVSLQSG----------------------PGHYAVP-TPRGTETGPR 93
             P   HS+   P S S + G                      P  Y  P +P G+E  P 
Sbjct: 1352 DPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPS 1411

Query: 94   TESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSESKSGREVGHHASSIPDA 153
              S+ HS  H     + T A++ S  +     P   AA       +GR       S  D 
Sbjct: 1412 PSSTAHSYGH-----SPTTANYGSQTEDLPQAPSGLAA-------AGRAAREKPLSASDG 1459

Query: 154  KSTHQLSFQDQKNNLQSQILEDDPPSKVQNPQ-------GARVPRRILSY---------- 196
            +         Q +   S      PP    +P        G   PR    +          
Sbjct: 1460 EGG-----TPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPA 1514

Query: 197  ---PKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSS--------CVSADYQTAQRRVPV 245
               P+     T        T     P +P L+   SS         +++D  +  R V  
Sbjct: 1515 SDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHA 1574

Query: 246  EESETGPYGPIPSKPKAL-YRNMNLDSLLKLSVLKDS-DGVHRV-SARVD-PESLHKYSA 301
              S +    P  ++P    Y      S+ +L        G  RV SA  D P +L+ + A
Sbjct: 1575 SASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGWGA 1634

Query: 302  YPETKPS----AKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSE 357
             P    S    + V  +S+VE   RTP  G + V  R  + P    +     + + S++ 
Sbjct: 1635 LPAENISLCRISSVPGTSRVEPGPRTP--GTAVVDLRTAVKP-TPIILTDQGMDLTSLAV 1691

Query: 358  GSHKSSMFVTPEPIYKQQTQKPPEITYMSQGPT 390
             + K  + + P P  +    +P  I   +Q  T
Sbjct: 1692 EARKYGLALDPIPGRQSTAVQPLVINLNAQEHT 1724


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 38.1 bits (87), Expect = 0.022
 Identities = 81/386 (20%), Positives = 147/386 (38%), Gaps = 40/386 (10%)

Query: 124 SPPREEAARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQN 183
           SPP EEAA    E+KS   V   A S  +AKS        +K   +S       P++V++
Sbjct: 503 SPPAEEAASPEKEAKS--PVKEEAKSPAEAKS-------PEKEEAKS-------PAEVKS 546

Query: 184 PQGARVPRRILSYPKDEAVQTEPIQRITTTSEIRSP---RSPSLLEHGSSCVSADYQTAQ 240
           P+ A+ P +  +    EA   E  +   + +E++SP   +SP+  E  S   +   + A+
Sbjct: 547 PEKAKSPAKEEAKSPPEAKSPEK-EEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK 605

Query: 241 RRVPVEESETGPYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYS 300
             V  EE+++      P K +A        + +K      S       +    +S  K  
Sbjct: 606 SPVK-EEAKSPAEAKSPVKEEA-----KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEE 659

Query: 301 AYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSEG-S 359
           A    K  + V   ++     ++P++  ++   +   SP  +  +       P   E  S
Sbjct: 660 AKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAK-SPVKEEAKSPEKAKSPVKEEAKS 718

Query: 360 HKSSMFVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKPSIHAELELTPRPLPPRSLP 419
            + +     E     +  K P           + PE ++   + +    TP     RS  
Sbjct: 719 PEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPA 778

Query: 420 RYGPDSSWWPLLNPEVETPQSQLTTPDFEPKCSPSLDLLLSGFKIDSSPFCEDLKFQREK 479
              P+ +  P +  EV++P+ +  +P  E   +P  ++          P  E++K   ++
Sbjct: 779 DKFPEKAKSP-VKEEVKSPE-KAKSPLKEDAKAPEKEI----------PKKEEVKSPVKE 826

Query: 480 ASLSPPSPPKEFPSWAPLSEVPQTPK 505
                    KE P  A   + P TPK
Sbjct: 827 EEKPQEVKVKEPPKKAEEEKAPATPK 852



 Score = 36.2 bits (82), Expect = 0.083
 Identities = 36/153 (23%), Positives = 62/153 (40%), Gaps = 14/153 (9%)

Query: 122 KVSPPREEAARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKV 181
           K   P +E A+   ++KS  +    A S   AKS  +   +  +        E   P K 
Sbjct: 637 KAKSPTKEEAKSPEKAKSPEK--EEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694

Query: 182 QNP--QGARVPRRILSYPKDEAVQTE----PIQRITTTSE-IRSP-----RSPSLLEHGS 229
           ++P  + A+ P +  S  K+EA   E    P++    T E  +SP     +SP   +   
Sbjct: 695 KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE 754

Query: 230 SCVSADYQTAQRRVPVEESETGPYGPIPSKPKA 262
              + D ++ + + P +E    P    P K K+
Sbjct: 755 KAKTLDVKSPEAKTPAKEEARSPADKFPEKAKS 787


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 37.7 bits (86), Expect = 0.029
 Identities = 98/468 (20%), Positives = 155/468 (33%), Gaps = 43/468 (9%)

Query: 3   KTNKPGAKVAVSAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPH 62
           K    G  +  S ++    T  +S  + +      S R  + S + S RRS +      H
Sbjct: 241 KVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRS-RPQSHSQSRSPRRSRSGSQKRTH 299

Query: 63  SASDYPRSVSLQSGPGHYAVPTPRG--TETGPRTESSRHSSPHLKSQKTQTLASHASSRQ 120
           S     RS S +         T +G  ++ G  ++S  HS    KSQ          S  
Sbjct: 300 SRV---RSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKG--KSQNQSRTPRRGRSHN 354

Query: 121 WKVSPPREEAARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSK 180
           W  +P +E +        S +E  H  SS P  +S      Q    N Q        P+K
Sbjct: 355 WSRNPSKERS--HSHSRSSSKERDHRGSSSPRKESGRS---QSGSPNKQRDHSRSRSPNK 409

Query: 181 VQNPQGARVPRRILSYPKDEAVQTEPIQRITTTSEIRSP---------RSPSLLEHGSSC 231
            ++   +R P     Y   +  ++    +    S  RSP         RSP+     S  
Sbjct: 410 ARDRSRSRSP-----YKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRS 464

Query: 232 VSAD--YQTAQRRVPVEESETGPYG-PIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVS 288
            S +     ++ R P +E +    G P   +     R+ + +   + S     +  HR S
Sbjct: 465 RSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRS 524

Query: 289 ARVDPESLHKYSAYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTH 348
                E   + S  P  +       S   E   R     + E  RR   SP   S E   
Sbjct: 525 RSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSP---SKERER 581

Query: 349 HVTVPSVSEGSHKSSMFVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKPSIHAELEL 408
             +  S  E  H  S     +  Y +      E  + S+  TP       K   H++   
Sbjct: 582 RQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAH-SRSRTP------SKEGNHSQSRT 634

Query: 409 TPRPLPP--RSLPRYGPDSSWWPLLNPEVETPQSQLTTPDFEPKCSPS 454
           + +   P   ++PR  PD    P     +   ++   T    P   PS
Sbjct: 635 SSKESDPSQSTVPR-SPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPS 681


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 37.7 bits (86), Expect = 0.029
 Identities = 38/152 (25%), Positives = 60/152 (39%), Gaps = 13/152 (8%)

Query: 20   EVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSLQSGPGH 79
            +V+T+   +  HG+   S+             R E A  ++ HSAS Y +  +++  PG 
Sbjct: 3065 QVSTHEQSESSHGWTGPSTRGRQG-------SRHEQAQDSSRHSASQYGQD-TIRGHPG- 3115

Query: 80   YAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSESKS 139
                + RG   G   E S  SS H  S  + T +   S      S  R  +    +E +S
Sbjct: 3116 ----SSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQS 3171

Query: 140  GREVGHHASSIPDAKSTHQLSFQDQKNNLQSQ 171
            G    H  S   +A +   +S   Q    QS+
Sbjct: 3172 GDSSRHSVSRHHEASTHADISRHSQAVQGQSE 3203



 Score = 36.6 bits (83), Expect = 0.064
 Identities = 34/145 (23%), Positives = 58/145 (40%), Gaps = 12/145 (8%)

Query: 14   SAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSH-RRSEAAHPTTPHSASDYPRSVS 72
            SA    +  T+ +    HG  ++ SH  A  S    H  R + +  ++ HS   + ++ S
Sbjct: 1322 SADSSRQSGTHHTESSSHGQAVS-SHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASS 1380

Query: 73   LQSGPGHYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAAR 132
                 GH      RG+     T S  HS    +   TQ++++H  +   + S       +
Sbjct: 1381 AVRDSGH------RGSSGSQVTNSEGHS----EDSDTQSVSAHGQAGPHQQSHKESARGQ 1430

Query: 133  RGSESKSGREVGHHASSIPDAKSTH 157
             G  S   R   +  SS   ++STH
Sbjct: 1431 SGESSGRSRSFLYQVSSHEQSESTH 1455



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 35/137 (25%), Positives = 54/137 (39%), Gaps = 9/137 (6%)

Query: 14   SAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSL 73
            S  RGS V+ + S  +GH     S  RS + S N      E +   + H  S +      
Sbjct: 2236 SRPRGSSVSQD-SDSEGHSE--DSERRSGSASRNHHGSAQEQSRDGSRHPRSHHED---- 2288

Query: 74   QSGPGHYAVPTPR-GTETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAAR 132
            ++G GH A  + + GT     +   + +S H +  ++     H S  Q      R     
Sbjct: 2289 RAGHGHSAESSRQSGTHHAENSSGGQAASSH-EQARSSAGERHGSHHQQSADSSRHSGIG 2347

Query: 133  RGSESKSGREVGHHASS 149
             G  S + R+ GH  SS
Sbjct: 2348 HGQASSAVRDSGHRGSS 2364



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 38/144 (26%), Positives = 56/144 (38%), Gaps = 23/144 (15%)

Query: 14   SAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHR-------RSEAAHPTTPHSASD 66
            S  +GS V+ + S  QGH     S   S + S N  HR       R  + HPT+ H    
Sbjct: 3532 SRNQGSSVSQD-SDSQGHSE--DSERWSGSASRN--HRGSAQEQSRDGSRHPTSHHED-- 3584

Query: 67   YPRSVSLQSGPGHYAVPTPR-GTETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSP 125
                   ++G GH A  + + GT     +   + +S H +  ++     H S  Q     
Sbjct: 3585 -------RAGHGHSAESSRQSGTHHAENSSGGQAASSH-EQARSSAGERHGSHHQQSADS 3636

Query: 126  PREEAARRGSESKSGREVGHHASS 149
             R      G  S + R+ GH  SS
Sbjct: 3637 SRHSGIGHGQASSAVRDSGHRGSS 3660



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 39/154 (25%), Positives = 57/154 (37%), Gaps = 26/154 (16%)

Query: 14   SAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSL 73
            S  R +   T    Q G G   + SH   A S   S R     H       S  PR+   
Sbjct: 2184 SGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSR-----HSLVGQGQSSGPRT--- 2235

Query: 74   QSGPGHYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPR------ 127
                       PRG+     ++S  HS    +   + +   H S+++      R      
Sbjct: 2236 ---------SRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHH 2286

Query: 128  EEAARRGSESKSGREVG-HHA--SSIPDAKSTHQ 158
            E+ A  G  ++S R+ G HHA  SS   A S+H+
Sbjct: 2287 EDRAGHGHSAESSRQSGTHHAENSSGGQAASSHE 2320



 Score = 33.1 bits (74), Expect = 0.70
 Identities = 37/152 (24%), Positives = 59/152 (38%), Gaps = 13/152 (8%)

Query: 20   EVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSLQSGPGH 79
            +V+T+   +  HG+   S+             R E A  ++ HSAS   +  +++  PG 
Sbjct: 2741 QVSTHEQSESSHGWTGPSTRGRQG-------SRHEQAQDSSRHSASQDGQD-TIRGHPG- 2791

Query: 80   YAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSESKS 139
                + RG   G   E S  SS H  S  + T +   S      S  R  +    +E +S
Sbjct: 2792 ----SSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQS 2847

Query: 140  GREVGHHASSIPDAKSTHQLSFQDQKNNLQSQ 171
            G    H  S   +A +   +S   Q    QS+
Sbjct: 2848 GDGSRHSGSRHHEASTHADISRHSQAVQGQSE 2879



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 43/176 (24%), Positives = 69/176 (39%), Gaps = 11/176 (6%)

Query: 14   SAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSL 73
            S ++GS V+ + S  +GH     S   S + S N  HR S  A   + H  S +PRS   
Sbjct: 939  SRRQGSSVSQD-SDSEGHSE--DSERWSGSASRN--HRGS--AQEQSRHG-SRHPRSHHE 990

Query: 74   -QSGPGHYAVPTPRGTETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAAR 132
             ++G GH A  + +       T S   ++   +  ++     H S  Q      R     
Sbjct: 991  DRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIP 1050

Query: 133  RGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNPQGAR 188
            R   S + R+ GH  SS   A  +   S +    ++       D P +  + + AR
Sbjct: 1051 RRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGH--GQDGPHQQSHQESAR 1104


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 37.7 bits (86), Expect = 0.029
 Identities = 83/429 (19%), Positives = 156/429 (36%), Gaps = 54/429 (12%)

Query: 2    VKTNKPGAKVAVSAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTP 61
            V T+ P     +  Q  S +T+            +++ RSA++S  P+   ++ +     
Sbjct: 8687 VSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATERSASLSGMPTGATTKVSRT--- 8743

Query: 62   HSASDYPRSVSLQSGPGHYAVPTPRGTETGPRTESSRHSSPHLKSQKT-QTLASHASSRQ 120
              A    R+ +   GP    +     TET  R  +   ++   +   T +T  S ASS+ 
Sbjct: 8744 -EALSLGRTST--PGPAQSTISPEISTETITRISTPLTTTGSAEMTITPKTGHSGASSQG 8800

Query: 121  WKVSPPREEAARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSK 180
                     A+  G+ S +     H   + P ++    +S+  + +     + +  PPS 
Sbjct: 8801 TFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPSRPS-----VEKTSPPSS 8855

Query: 181  VQNPQGARVPRRILSYPKDEAVQTEPIQ--------RITTTSEIRSPRSPSLLEHGSSCV 232
            + +      P  + S P  E+  + P++         + TT  + +   P      S  +
Sbjct: 8856 LVSLSAVTSPSPLYSTPS-ESSHSSPLRVTSLFTPVMMKTTDMLDTSLEPVTTSPPSMNI 8914

Query: 233  SADYQTAQRRVPVEESETGPYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVD 292
            ++D   A  +  +E                          ++LS       +  +SAR  
Sbjct: 8915 TSDESLATSKATMETEA-----------------------IQLSENTAVTQMGTISAR-- 8949

Query: 293  PESLHKYSAYPE-TKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVT 351
             E    Y   PE +K ++ V+ SS ++  V T I  +SE+ R    S    +  P    T
Sbjct: 8950 QEFYSSYPGLPEPSKVTSPVVTSSTIKDIVSTTIPASSEITRIEMESTSTLTPTPRETST 9009

Query: 352  VPSVSEGSHKSSM---FVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKPSIHAELEL 408
               +   +  S++    +T   I    TQ    +   S+GP+P    +SQ  S      L
Sbjct: 9010 SQEIHSATKPSTVPYKALTSATIEDSMTQ----VMSSSRGPSPDQSTMSQDISTEVITRL 9065

Query: 409  TPRPLPPRS 417
            +  P+   S
Sbjct: 9066 STSPIKTES 9074


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,884,719
Number of Sequences: 37866
Number of extensions: 1470602
Number of successful extensions: 6077
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 345
Number of HSP's that attempted gapping in prelim test: 5335
Number of HSP's gapped (non-prelim): 1059
length of query: 570
length of database: 18,247,518
effective HSP length: 108
effective length of query: 462
effective length of database: 14,157,990
effective search space: 6540991380
effective search space used: 6540991380
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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