Guide to the Human Genome
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Search of human proteins with 83977452

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|83977452 discoidin domain receptor family, member 1 isoform
c [Homo sapiens]
         (919 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|83977452 discoidin domain receptor family, member 1 isoform c...  1902   0.0  
gi|83977450 discoidin domain receptor family, member 1 isoform a...  1885   0.0  
gi|38327632 discoidin domain receptor family, member 1 isoform b...  1789   0.0  
gi|62420886 discoidin domain receptor family, member 2 precursor...   905   0.0  
gi|62420884 discoidin domain receptor family, member 2 precursor...   905   0.0  
gi|65506745 neurotrophic tyrosine kinase, receptor, type 2 isofo...   241   3e-63
gi|21361306 neurotrophic tyrosine kinase, receptor, type 2 isofo...   241   3e-63
gi|59889560 neurotrophic tyrosine kinase, receptor, type 3 isofo...   235   1e-61
gi|59889558 neurotrophic tyrosine kinase, receptor, type 1 isofo...   231   2e-60
gi|4585712 neurotrophic tyrosine kinase, receptor, type 1 isofor...   231   2e-60
gi|56118210 neurotrophic tyrosine kinase, receptor, type 1 isofo...   231   2e-60
gi|59889562 neurotrophic tyrosine kinase, receptor, type 3 isofo...   226   1e-58
gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens]    219   9e-57
gi|134152725 receptor tyrosine kinase-like orphan receptor 1 iso...   202   9e-52
gi|119395738 insulin receptor isoform Short precursor [Homo sapi...   198   2e-50
gi|119395736 insulin receptor isoform Long precursor [Homo sapiens]   198   2e-50
gi|31657140 insulin receptor-related receptor precursor [Homo sa...   191   2e-48
gi|19743898 receptor tyrosine kinase-like orphan receptor 2 prec...   191   2e-48
gi|19924165 proto-oncogene c-ros-1 protein precursor [Homo sapiens]   191   2e-48
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a...   191   4e-48
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b...   191   4e-48
gi|4557665 insulin-like growth factor 1 receptor precursor [Homo...   189   1e-47
gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]             186   9e-47
gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]               186   9e-47
gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]             186   9e-47
gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]             186   9e-47
gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]             186   9e-47
gi|47524177 fibroblast growth factor receptor 4 isoform 2 precur...   184   3e-46
gi|47524175 fibroblast growth factor receptor 4 isoform 1 precur...   184   3e-46
gi|47524173 fibroblast growth factor receptor 4 isoform 1 precur...   184   3e-46

>gi|83977452 discoidin domain receptor family, member 1 isoform c
           [Homo sapiens]
          Length = 919

 Score = 1902 bits (4928), Expect = 0.0
 Identities = 919/919 (100%), Positives = 919/919 (100%)

Query: 1   MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAAR 60
           MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAAR
Sbjct: 1   MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAAR 60

Query: 61  HSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRL 120
           HSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRL
Sbjct: 61  HSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRL 120

Query: 121 RYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV 180
           RYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
Sbjct: 121 RYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV 180

Query: 181 ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDD 240
           ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDD
Sbjct: 181 ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDD 240

Query: 241 FRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGG 300
           FRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGG
Sbjct: 241 FRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGG 300

Query: 301 VECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS 360
           VECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
Sbjct: 301 VECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS 360

Query: 361 EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILI 420
           EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILI
Sbjct: 361 EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILI 420

Query: 421 GCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPRE 480
           GCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPRE
Sbjct: 421 GCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPRE 480

Query: 481 PPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNT 540
           PPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNT
Sbjct: 481 PPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNT 540

Query: 541 QAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGP 600
           QAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGP
Sbjct: 541 QAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGP 600

Query: 601 PRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPD 660
           PRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPD
Sbjct: 601 PRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPD 660

Query: 661 ATKNASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLS 720
           ATKNASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLS
Sbjct: 661 ATKNASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLS 720

Query: 721 AHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV 780
           AHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV
Sbjct: 721 AHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV 780

Query: 781 GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLW 840
           GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLW
Sbjct: 781 GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLW 840

Query: 841 EVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQ 900
           EVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQ
Sbjct: 841 EVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQ 900

Query: 901 RPPFSQLHRFLAEDALNTV 919
           RPPFSQLHRFLAEDALNTV
Sbjct: 901 RPPFSQLHRFLAEDALNTV 919


>gi|83977450 discoidin domain receptor family, member 1 isoform a
           [Homo sapiens]
          Length = 913

 Score = 1885 bits (4883), Expect = 0.0
 Identities = 913/919 (99%), Positives = 913/919 (99%), Gaps = 6/919 (0%)

Query: 1   MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAAR 60
           MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAAR
Sbjct: 1   MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAAR 60

Query: 61  HSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRL 120
           HSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRL
Sbjct: 61  HSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRL 120

Query: 121 RYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV 180
           RYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
Sbjct: 121 RYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV 180

Query: 181 ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDD 240
           ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDD
Sbjct: 181 ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDD 240

Query: 241 FRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGG 300
           FRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGG
Sbjct: 241 FRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGG 300

Query: 301 VECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS 360
           VECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
Sbjct: 301 VECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS 360

Query: 361 EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILI 420
           EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILI
Sbjct: 361 EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILI 420

Query: 421 GCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPRE 480
           GCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPRE
Sbjct: 421 GCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPRE 480

Query: 481 PPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNT 540
           PPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNT
Sbjct: 481 PPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNT 540

Query: 541 QAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGP 600
           QAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGP
Sbjct: 541 QAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGP 600

Query: 601 PRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPD 660
           PRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPD
Sbjct: 601 PRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPD 660

Query: 661 ATKNASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLS 720
           ATKNA      RNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLS
Sbjct: 661 ATKNA------RNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLS 714

Query: 721 AHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV 780
           AHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV
Sbjct: 715 AHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV 774

Query: 781 GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLW 840
           GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLW
Sbjct: 775 GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLW 834

Query: 841 EVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQ 900
           EVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQ
Sbjct: 835 EVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQ 894

Query: 901 RPPFSQLHRFLAEDALNTV 919
           RPPFSQLHRFLAEDALNTV
Sbjct: 895 RPPFSQLHRFLAEDALNTV 913


>gi|38327632 discoidin domain receptor family, member 1 isoform b
           [Homo sapiens]
          Length = 876

 Score = 1789 bits (4633), Expect = 0.0
 Identities = 876/919 (95%), Positives = 876/919 (95%), Gaps = 43/919 (4%)

Query: 1   MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAAR 60
           MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAAR
Sbjct: 1   MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAAR 60

Query: 61  HSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRL 120
           HSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRL
Sbjct: 61  HSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRL 120

Query: 121 RYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV 180
           RYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
Sbjct: 121 RYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV 180

Query: 181 ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDD 240
           ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDD
Sbjct: 181 ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDD 240

Query: 241 FRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGG 300
           FRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGG
Sbjct: 241 FRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGG 300

Query: 301 VECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS 360
           VECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
Sbjct: 301 VECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS 360

Query: 361 EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILI 420
           EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILI
Sbjct: 361 EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILI 420

Query: 421 GCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPRE 480
           GCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPRE
Sbjct: 421 GCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPRE 480

Query: 481 PPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNT 540
           PPPYQEPRPRGNPPHSAPCVPNGS                                    
Sbjct: 481 PPPYQEPRPRGNPPHSAPCVPNGS------------------------------------ 504

Query: 541 QAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGP 600
            AYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGP
Sbjct: 505 -AYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGP 563

Query: 601 PRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPD 660
           PRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPD
Sbjct: 564 PRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPD 623

Query: 661 ATKNASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLS 720
           ATKNA      RNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLS
Sbjct: 624 ATKNA------RNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLS 677

Query: 721 AHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV 780
           AHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV
Sbjct: 678 AHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV 737

Query: 781 GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLW 840
           GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLW
Sbjct: 738 GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLW 797

Query: 841 EVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQ 900
           EVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQ
Sbjct: 798 EVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQ 857

Query: 901 RPPFSQLHRFLAEDALNTV 919
           RPPFSQLHRFLAEDALNTV
Sbjct: 858 RPPFSQLHRFLAEDALNTV 876


>gi|62420886 discoidin domain receptor family, member 2 precursor
           [Homo sapiens]
          Length = 855

 Score =  905 bits (2339), Expect = 0.0
 Identities = 480/916 (52%), Positives = 598/916 (65%), Gaps = 74/916 (8%)

Query: 3   PEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHS 62
           P  L  L LLL + S     K   +PA CRY LGM    IPD DI+ASS WS+STAA++ 
Sbjct: 5   PRMLLVLFLLLPILSS---AKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYG 61

Query: 63  RLESSDGDGAWCPAGSVFPKE-EEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLR 121
           RL+S +GDGAWCP   V P + +E+LQ+DL  LH + LVGTQGRHAGG G EF+  Y++ 
Sbjct: 62  RLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKIN 121

Query: 122 YSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVE 181
           YSRDG RW+ W++R G++V+ GN +P  + LKDL PP+VAR VRF P  D  M+VC+RVE
Sbjct: 122 YSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVE 181

Query: 182 LYGCLWRDGLLSYTAPVGQTMYL--SEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLD 239
           LYGC+W DGL+SY AP GQ   L     +YLNDS YDG  VG     GLGQL DGV GLD
Sbjct: 182 LYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDG-AVGYSMTEGLGQLTDGVSGLD 240

Query: 240 DFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPG 299
           DF ++ E  VWPGYDYVGW N S ++GY+E+ FEFDR+R F  M+VHCNNM   G ++  
Sbjct: 241 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK 300

Query: 300 GVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLF 359
            V+C FR   A  WE   +   L  +  +P AR V+VPL  R+A  ++C++ FA  W++F
Sbjct: 301 EVQCYFR-SEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMF 359

Query: 360 SEISFISDV-VNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAI 418
           SEI+F SD  + N+S AL    P +P               + P    P+ K + S T I
Sbjct: 360 SEITFQSDAAMYNNSEAL----PTSP---------------MAPTTYDPMLKVDDSNTRI 400

Query: 419 LIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGP 478
           LIGCLVAII +LL II ++LWR  W+++L KA RR+L++E+TV LS+P D+ + NN    
Sbjct: 401 LIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNN--- 457

Query: 479 REPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPT 538
                      R + P           +    P Y+         P       P +A   
Sbjct: 458 -----------RSSSPSEQGSNSTYDRIFPLRPDYQ--------EPSRLIRKLPEFAPGE 498

Query: 539 NTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGD 598
                SG  ++P +P  P         VPHYAEADIV LQGVTGGNTY+VPA+    +  
Sbjct: 499 EESGCSG-VVKPVQPSGP-------EGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSG 550

Query: 599 GPPRVD-FPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKIL 657
               V+ FPR  L FKEKLGEGQFGEVHLCEV+  +     DF L+V    P+LVAVK+L
Sbjct: 551 KDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKML 610

Query: 658 RPDATKNASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQ 717
           R DA KNA      RNDFLKE+KIMSRLKDPNII LL VC+ DDPLCMIT+YMENGDLNQ
Sbjct: 611 RADANKNA------RNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQ 664

Query: 718 FLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRN 777
           FLS H+         P +  ++   T+SY  L  +A QIASGM+YL++LNFVHRDLATRN
Sbjct: 665 FLSRHE---------PPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRN 715

Query: 778 CLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGV 837
           CLVG+N+TIKIADFGMSRNLY+GDYYR+QGRAVLPIRWM+WE IL+GKFTTASDVWAFGV
Sbjct: 716 CLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGV 775

Query: 838 TLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRE 897
           TLWE    C+ QP+ QL+DEQVIEN GEFFRDQGRQ YL +P  CP  +Y+LML CW R+
Sbjct: 776 TLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRD 835

Query: 898 SEQRPPFSQLHRFLAE 913
           ++ RP F ++H  L +
Sbjct: 836 TKNRPSFQEIHLLLLQ 851


>gi|62420884 discoidin domain receptor family, member 2 precursor
           [Homo sapiens]
          Length = 855

 Score =  905 bits (2339), Expect = 0.0
 Identities = 480/916 (52%), Positives = 598/916 (65%), Gaps = 74/916 (8%)

Query: 3   PEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHS 62
           P  L  L LLL + S     K   +PA CRY LGM    IPD DI+ASS WS+STAA++ 
Sbjct: 5   PRMLLVLFLLLPILSS---AKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYG 61

Query: 63  RLESSDGDGAWCPAGSVFPKE-EEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLR 121
           RL+S +GDGAWCP   V P + +E+LQ+DL  LH + LVGTQGRHAGG G EF+  Y++ 
Sbjct: 62  RLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKIN 121

Query: 122 YSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVE 181
           YSRDG RW+ W++R G++V+ GN +P  + LKDL PP+VAR VRF P  D  M+VC+RVE
Sbjct: 122 YSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVE 181

Query: 182 LYGCLWRDGLLSYTAPVGQTMYL--SEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLD 239
           LYGC+W DGL+SY AP GQ   L     +YLNDS YDG  VG     GLGQL DGV GLD
Sbjct: 182 LYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDG-AVGYSMTEGLGQLTDGVSGLD 240

Query: 240 DFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPG 299
           DF ++ E  VWPGYDYVGW N S ++GY+E+ FEFDR+R F  M+VHCNNM   G ++  
Sbjct: 241 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK 300

Query: 300 GVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLF 359
            V+C FR   A  WE   +   L  +  +P AR V+VPL  R+A  ++C++ FA  W++F
Sbjct: 301 EVQCYFR-SEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMF 359

Query: 360 SEISFISDV-VNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAI 418
           SEI+F SD  + N+S AL    P +P               + P    P+ K + S T I
Sbjct: 360 SEITFQSDAAMYNNSEAL----PTSP---------------MAPTTYDPMLKVDDSNTRI 400

Query: 419 LIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGP 478
           LIGCLVAII +LL II ++LWR  W+++L KA RR+L++E+TV LS+P D+ + NN    
Sbjct: 401 LIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNN--- 457

Query: 479 REPPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPT 538
                      R + P           +    P Y+         P       P +A   
Sbjct: 458 -----------RSSSPSEQGSNSTYDRIFPLRPDYQ--------EPSRLIRKLPEFAPGE 498

Query: 539 NTQAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGD 598
                SG  ++P +P  P         VPHYAEADIV LQGVTGGNTY+VPA+    +  
Sbjct: 499 EESGCSG-VVKPVQPSGP-------EGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSG 550

Query: 599 GPPRVD-FPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKIL 657
               V+ FPR  L FKEKLGEGQFGEVHLCEV+  +     DF L+V    P+LVAVK+L
Sbjct: 551 KDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKML 610

Query: 658 RPDATKNASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQ 717
           R DA KNA      RNDFLKE+KIMSRLKDPNII LL VC+ DDPLCMIT+YMENGDLNQ
Sbjct: 611 RADANKNA------RNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQ 664

Query: 718 FLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRN 777
           FLS H+         P +  ++   T+SY  L  +A QIASGM+YL++LNFVHRDLATRN
Sbjct: 665 FLSRHE---------PPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRN 715

Query: 778 CLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGV 837
           CLVG+N+TIKIADFGMSRNLY+GDYYR+QGRAVLPIRWM+WE IL+GKFTTASDVWAFGV
Sbjct: 716 CLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGV 775

Query: 838 TLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRE 897
           TLWE    C+ QP+ QL+DEQVIEN GEFFRDQGRQ YL +P  CP  +Y+LML CW R+
Sbjct: 776 TLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRD 835

Query: 898 SEQRPPFSQLHRFLAE 913
           ++ RP F ++H  L +
Sbjct: 836 TKNRPSFQEIHLLLLQ 851


>gi|65506745 neurotrophic tyrosine kinase, receptor, type 2 isoform
           c precursor [Homo sapiens]
          Length = 822

 Score =  241 bits (614), Expect = 3e-63
 Identities = 144/310 (46%), Positives = 189/310 (60%), Gaps = 42/310 (13%)

Query: 607 RSRLRFKEKLGEGQFGEVHLCEVDS---PQDLVSLDFPLNVRKGHPLLVAVKILRPDATK 663
           R  +  K +LGEG FG+V L E  +    QD +              LVAVK L+ DA+ 
Sbjct: 535 RHNIVLKRELGEGAFGKVFLAECYNLCPEQDKI--------------LVAVKTLK-DASD 579

Query: 664 NASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQ 723
           NA      R DF +E ++++ L+  +I++  GVCV+ DPL M+ +YM++GDLN+FL AH 
Sbjct: 580 NA------RKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 633

Query: 724 LEDKA-AEGAPGDGQAAQGPT-ISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVG 781
            +    AEG P        PT ++   +LH+A QIA+GM YLA+ +FVHRDLATRNCLVG
Sbjct: 634 PDAVLMAEGNP--------PTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVG 685

Query: 782 ENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWE 841
           EN  +KI DFGMSR++Y+ DYYRV G  +LPIRWM  E I+  KFTT SDVW+ GV LWE
Sbjct: 686 ENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWE 745

Query: 842 VLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQR 901
           +    + QP+ QL++ +VIE        QGR   L RP  CPQ +YELML CW RE   R
Sbjct: 746 IFTYGK-QPWYQLSNNEVIECI-----TQGR--VLQRPRTCPQEVYELMLGCWQREPHMR 797

Query: 902 PPFSQLHRFL 911
                +H  L
Sbjct: 798 KNIKGIHTLL 807


>gi|21361306 neurotrophic tyrosine kinase, receptor, type 2 isoform
           a precursor [Homo sapiens]
          Length = 838

 Score =  241 bits (614), Expect = 3e-63
 Identities = 144/310 (46%), Positives = 189/310 (60%), Gaps = 42/310 (13%)

Query: 607 RSRLRFKEKLGEGQFGEVHLCEVDS---PQDLVSLDFPLNVRKGHPLLVAVKILRPDATK 663
           R  +  K +LGEG FG+V L E  +    QD +              LVAVK L+ DA+ 
Sbjct: 551 RHNIVLKRELGEGAFGKVFLAECYNLCPEQDKI--------------LVAVKTLK-DASD 595

Query: 664 NASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQ 723
           NA      R DF +E ++++ L+  +I++  GVCV+ DPL M+ +YM++GDLN+FL AH 
Sbjct: 596 NA------RKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 649

Query: 724 LEDKA-AEGAPGDGQAAQGPT-ISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVG 781
            +    AEG P        PT ++   +LH+A QIA+GM YLA+ +FVHRDLATRNCLVG
Sbjct: 650 PDAVLMAEGNP--------PTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVG 701

Query: 782 ENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWE 841
           EN  +KI DFGMSR++Y+ DYYRV G  +LPIRWM  E I+  KFTT SDVW+ GV LWE
Sbjct: 702 ENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWE 761

Query: 842 VLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQR 901
           +    + QP+ QL++ +VIE        QGR   L RP  CPQ +YELML CW RE   R
Sbjct: 762 IFTYGK-QPWYQLSNNEVIECI-----TQGR--VLQRPRTCPQEVYELMLGCWQREPHMR 813

Query: 902 PPFSQLHRFL 911
                +H  L
Sbjct: 814 KNIKGIHTLL 823


>gi|59889560 neurotrophic tyrosine kinase, receptor, type 3 isoform
           b precursor [Homo sapiens]
          Length = 825

 Score =  235 bits (600), Expect = 1e-61
 Identities = 136/306 (44%), Positives = 188/306 (61%), Gaps = 31/306 (10%)

Query: 607 RSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNAS 666
           R  +  K +LGEG FG+V L E           + L+  K   +LVAVK L+        
Sbjct: 535 RRDIVLKRELGEGAFGKVFLAEC----------YNLSPTKDK-MLVAVKALKDP------ 577

Query: 667 FSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLED 726
            +L +R DF +E ++++ L+  +I++  GVC   DPL M+ +YM++GDLN+FL AH  + 
Sbjct: 578 -TLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDA 636

Query: 727 KAAEGAPGDGQAAQGP-TISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFT 785
                   DGQ  Q    +    +LH+A+QIASGM YLA+ +FVHRDLATRNCLVG N  
Sbjct: 637 MILV----DGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLL 692

Query: 786 IKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLML 845
           +KI DFGMSR++Y+ DYYRV G  +LPIRWM  E I+  KFTT SDVW+FGV LWE+   
Sbjct: 693 VKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTY 752

Query: 846 CRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFS 905
            + QP+ QL++ +VIE        QGR   L RP  CP+ +Y++ML CW RE +QR    
Sbjct: 753 GK-QPWFQLSNTEVIECI-----TQGR--VLERPRVCPKEVYDVMLGCWQREPQQRLNIK 804

Query: 906 QLHRFL 911
           ++++ L
Sbjct: 805 EIYKIL 810


>gi|59889558 neurotrophic tyrosine kinase, receptor, type 1 isoform
           1 [Homo sapiens]
          Length = 790

 Score =  231 bits (589), Expect = 2e-60
 Identities = 134/302 (44%), Positives = 185/302 (61%), Gaps = 30/302 (9%)

Query: 607 RSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNAS 666
           R  +  K +LGEG FG+V L E  +            + +   +LVAVK L+ +A+++A 
Sbjct: 501 RRDIVLKWELGEGAFGKVFLAECHNL-----------LPEQDKMLVAVKALK-EASESA- 547

Query: 667 FSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLED 726
                R DF +E ++++ L+  +I+R  GVC +  PL M+ +YM +GDLN+FL +H  + 
Sbjct: 548 -----RQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDA 602

Query: 727 KAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTI 786
           K   G       A GP +    LL VA+Q+A+GM YLA L+FVHRDLATRNCLVG+   +
Sbjct: 603 KLLAGGE---DVAPGP-LGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVV 658

Query: 787 KIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLC 846
           KI DFGMSR++Y+ DYYRV GR +LPIRWM  E IL  KFTT SDVW+FGV LWE+    
Sbjct: 659 KIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYG 718

Query: 847 RAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQ 906
           + QP+ QL++ + I+        QGR+  L RP ACP  +Y +M  CW RE +QR     
Sbjct: 719 K-QPWYQLSNTEAIDCI-----TQGRE--LERPRACPPEVYAIMRGCWQREPQQRHSIKD 770

Query: 907 LH 908
           +H
Sbjct: 771 VH 772


>gi|4585712 neurotrophic tyrosine kinase, receptor, type 1 isoform 2
           [Homo sapiens]
          Length = 796

 Score =  231 bits (589), Expect = 2e-60
 Identities = 134/302 (44%), Positives = 185/302 (61%), Gaps = 30/302 (9%)

Query: 607 RSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNAS 666
           R  +  K +LGEG FG+V L E  +            + +   +LVAVK L+ +A+++A 
Sbjct: 507 RRDIVLKWELGEGAFGKVFLAECHNL-----------LPEQDKMLVAVKALK-EASESA- 553

Query: 667 FSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLED 726
                R DF +E ++++ L+  +I+R  GVC +  PL M+ +YM +GDLN+FL +H  + 
Sbjct: 554 -----RQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDA 608

Query: 727 KAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTI 786
           K   G       A GP +    LL VA+Q+A+GM YLA L+FVHRDLATRNCLVG+   +
Sbjct: 609 KLLAGGE---DVAPGP-LGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVV 664

Query: 787 KIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLC 846
           KI DFGMSR++Y+ DYYRV GR +LPIRWM  E IL  KFTT SDVW+FGV LWE+    
Sbjct: 665 KIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYG 724

Query: 847 RAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQ 906
           + QP+ QL++ + I+        QGR+  L RP ACP  +Y +M  CW RE +QR     
Sbjct: 725 K-QPWYQLSNTEAIDCI-----TQGRE--LERPRACPPEVYAIMRGCWQREPQQRHSIKD 776

Query: 907 LH 908
           +H
Sbjct: 777 VH 778


>gi|56118210 neurotrophic tyrosine kinase, receptor, type 1 isoform
           3 [Homo sapiens]
          Length = 760

 Score =  231 bits (589), Expect = 2e-60
 Identities = 134/302 (44%), Positives = 185/302 (61%), Gaps = 30/302 (9%)

Query: 607 RSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNAS 666
           R  +  K +LGEG FG+V L E  +            + +   +LVAVK L+ +A+++A 
Sbjct: 471 RRDIVLKWELGEGAFGKVFLAECHNL-----------LPEQDKMLVAVKALK-EASESA- 517

Query: 667 FSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLED 726
                R DF +E ++++ L+  +I+R  GVC +  PL M+ +YM +GDLN+FL +H  + 
Sbjct: 518 -----RQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDA 572

Query: 727 KAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTI 786
           K   G       A GP +    LL VA+Q+A+GM YLA L+FVHRDLATRNCLVG+   +
Sbjct: 573 KLLAGGE---DVAPGP-LGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVV 628

Query: 787 KIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLC 846
           KI DFGMSR++Y+ DYYRV GR +LPIRWM  E IL  KFTT SDVW+FGV LWE+    
Sbjct: 629 KIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYG 688

Query: 847 RAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQ 906
           + QP+ QL++ + I+        QGR+  L RP ACP  +Y +M  CW RE +QR     
Sbjct: 689 K-QPWYQLSNTEAIDCI-----TQGRE--LERPRACPPEVYAIMRGCWQREPQQRHSIKD 740

Query: 907 LH 908
           +H
Sbjct: 741 VH 742


>gi|59889562 neurotrophic tyrosine kinase, receptor, type 3 isoform
           a precursor [Homo sapiens]
          Length = 839

 Score =  226 bits (575), Expect = 1e-58
 Identities = 136/320 (42%), Positives = 188/320 (58%), Gaps = 45/320 (14%)

Query: 607 RSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNAS 666
           R  +  K +LGEG FG+V L E           + L+  K   +LVAVK L+        
Sbjct: 535 RRDIVLKRELGEGAFGKVFLAEC----------YNLSPTKDK-MLVAVKALKDP------ 577

Query: 667 FSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLED 726
            +L +R DF +E ++++ L+  +I++  GVC   DPL M+ +YM++GDLN+FL AH  + 
Sbjct: 578 -TLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDA 636

Query: 727 KAAEGAPGDGQAAQGP-TISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFT 785
                   DGQ  Q    +    +LH+A+QIASGM YLA+ +FVHRDLATRNCLVG N  
Sbjct: 637 MILV----DGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLL 692

Query: 786 IKIADFGMSRNLYAGDYYR--------------VQGRAVLPIRWMAWECILMGKFTTASD 831
           +KI DFGMSR++Y+ DYYR              V G  +LPIRWM  E I+  KFTT SD
Sbjct: 693 VKIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESD 752

Query: 832 VWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELML 891
           VW+FGV LWE+    + QP+ QL++ +VIE        QGR   L RP  CP+ +Y++ML
Sbjct: 753 VWSFGVILWEIFTYGK-QPWFQLSNTEVIECI-----TQGR--VLERPRVCPKEVYDVML 804

Query: 892 RCWSRESEQRPPFSQLHRFL 911
            CW RE +QR    ++++ L
Sbjct: 805 GCWQREPQQRLNIKEIYKIL 824


>gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens]
          Length = 869

 Score =  219 bits (558), Expect = 9e-57
 Identities = 127/320 (39%), Positives = 178/320 (55%), Gaps = 42/320 (13%)

Query: 603 VDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDAT 662
           +++PR+ + +   +GEG FG V   +  +P  L    F +         VAVK+L+ +A+
Sbjct: 568 LEYPRNNIEYVRDIGEGAFGRVF--QARAPGLLPYEPFTM---------VAVKMLKEEAS 616

Query: 663 KNASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFL--- 719
            +       + DF +E  +M+   +PNI++LLGVC    P+C++ +YM  GDLN+FL   
Sbjct: 617 ADM------QADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSM 670

Query: 720 --------SAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHR 771
                   S   L  +A   +PG       P +S    L +A Q+A+GM YL+   FVHR
Sbjct: 671 SPHTVCSLSHSDLSMRAQVSSPGP------PPLSCAEQLCIARQVAAGMAYLSERKFVHR 724

Query: 772 DLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASD 831
           DLATRNCLVGEN  +KIADFG+SRN+Y+ DYY+      +PIRWM  E I   ++TT SD
Sbjct: 725 DLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESD 784

Query: 832 VWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELML 891
           VWA+GV LWE+      QP+  +  E+VI     + RD      LS P  CP  LY LM 
Sbjct: 785 VWAYGVVLWEIFSY-GLQPYYGMAHEEVI----YYVRDGN---ILSCPENCPVELYNLMR 836

Query: 892 RCWSRESEQRPPFSQLHRFL 911
            CWS+    RP F+ +HR L
Sbjct: 837 LCWSKLPADRPSFTSIHRIL 856


>gi|134152725 receptor tyrosine kinase-like orphan receptor 1
           isoform 1 [Homo sapiens]
          Length = 937

 Score =  202 bits (515), Expect = 9e-52
 Identities = 114/305 (37%), Positives = 173/305 (56%), Gaps = 28/305 (9%)

Query: 604 DFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATK 663
           + P S +RF E+LGE  FG+++   +  P     +D        H  LVA+K L+ D   
Sbjct: 467 ELPLSAVRFMEELGECAFGKIYKGHLYLP----GMD--------HAQLVAIKTLK-DYNN 513

Query: 664 NASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQ 723
              ++     +F +E  +M+ L  PNI+ LLG   Q+ P+CM+ +Y+  GDL++FL    
Sbjct: 514 PQQWT-----EFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRS 568

Query: 724 LEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGEN 783
                   +  DG      ++ +   LH+A QIA+GM YL++  FVH+DLA RN L+GE 
Sbjct: 569 PHSDVGCSSDEDGTVKS--SLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQ 626

Query: 784 FTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVL 843
             +KI+D G+SR +Y+ DYYRVQ +++LPIRWM  E I+ GKF++ SD+W+FGV LWE+ 
Sbjct: 627 LHVKISDLGLSREIYSADYYRVQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIF 686

Query: 844 MLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPP 903
                QP+   ++++VIE        + RQ+ L     CP  +Y LM  CW+    +RP 
Sbjct: 687 SF-GLQPYYGFSNQEVIEMV------RKRQL-LPCSEDCPPRMYSLMTECWNEIPSRRPR 738

Query: 904 FSQLH 908
           F  +H
Sbjct: 739 FKDIH 743


>gi|119395738 insulin receptor isoform Short precursor [Homo sapiens]
          Length = 1370

 Score =  198 bits (503), Expect = 2e-50
 Identities = 118/315 (37%), Positives = 174/315 (55%), Gaps = 34/315 (10%)

Query: 600  PPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRP 659
            P   +  R ++    +LG+G FG V+     + +D++  +    V        AVK    
Sbjct: 1001 PDEWEVSREKITLLRELGQGSFGMVY---EGNARDIIKGEAETRV--------AVK---- 1045

Query: 660  DATKNASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFL 719
              T N S SL  R +FL E  +M      +++RLLGV  +  P  ++ + M +GDL  +L
Sbjct: 1046 --TVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYL 1103

Query: 720  SAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCL 779
             + + E   AE  PG       P  +   ++ +AA+IA GM YL    FVHRDLA RNC+
Sbjct: 1104 RSLRPE---AENNPGR------PPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCM 1154

Query: 780  VGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTL 839
            V  +FT+KI DFGM+R++Y  DYYR  G+ +LP+RWMA E +  G FTT+SD+W+FGV L
Sbjct: 1155 VAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVL 1214

Query: 840  WEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESE 899
            WE+  L   QP+  L++EQV+    +F  D G   YL +P  CP+ + +LM  CW    +
Sbjct: 1215 WEITSLAE-QPYQGLSNEQVL----KFVMDGG---YLDQPDNCPERVTDLMRMCWQFNPK 1266

Query: 900  QRPPFSQLHRFLAED 914
             RP F ++   L +D
Sbjct: 1267 MRPTFLEIVNLLKDD 1281


>gi|119395736 insulin receptor isoform Long precursor [Homo sapiens]
          Length = 1382

 Score =  198 bits (503), Expect = 2e-50
 Identities = 118/315 (37%), Positives = 174/315 (55%), Gaps = 34/315 (10%)

Query: 600  PPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRP 659
            P   +  R ++    +LG+G FG V+     + +D++  +    V        AVK    
Sbjct: 1013 PDEWEVSREKITLLRELGQGSFGMVY---EGNARDIIKGEAETRV--------AVK---- 1057

Query: 660  DATKNASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFL 719
              T N S SL  R +FL E  +M      +++RLLGV  +  P  ++ + M +GDL  +L
Sbjct: 1058 --TVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYL 1115

Query: 720  SAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCL 779
             + + E   AE  PG       P  +   ++ +AA+IA GM YL    FVHRDLA RNC+
Sbjct: 1116 RSLRPE---AENNPGR------PPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCM 1166

Query: 780  VGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTL 839
            V  +FT+KI DFGM+R++Y  DYYR  G+ +LP+RWMA E +  G FTT+SD+W+FGV L
Sbjct: 1167 VAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVL 1226

Query: 840  WEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESE 899
            WE+  L   QP+  L++EQV+    +F  D G   YL +P  CP+ + +LM  CW    +
Sbjct: 1227 WEITSLAE-QPYQGLSNEQVL----KFVMDGG---YLDQPDNCPERVTDLMRMCWQFNPK 1278

Query: 900  QRPPFSQLHRFLAED 914
             RP F ++   L +D
Sbjct: 1279 MRPTFLEIVNLLKDD 1293


>gi|31657140 insulin receptor-related receptor precursor [Homo
            sapiens]
          Length = 1297

 Score =  191 bits (486), Expect = 2e-48
 Identities = 122/317 (38%), Positives = 168/317 (52%), Gaps = 38/317 (11%)

Query: 600  PPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRP 659
            P   + PR ++    +LG+G FG V+                  + +G   L A +   P
Sbjct: 969  PDEWEVPREQISIIRELGQGSFGMVYE----------------GLARG---LEAGEESTP 1009

Query: 660  DATKNASFSLFSRN--DFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQ 717
             A K  +     R   +FLKE  +M   K  +++RLLGV  Q  P  +I + M  GDL  
Sbjct: 1010 VALKTVNELASPRECIEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKS 1069

Query: 718  FLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRN 777
             L + + E   AE  PG  Q A G       ++ +A +IA GM YLA   FVHRDLA RN
Sbjct: 1070 HLRSLRPE---AENNPGLPQPALGE------MIQMAGEIADGMAYLAANKFVHRDLAARN 1120

Query: 778  CLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGV 837
            C+V ++FT+KI DFGM+R++Y  DYYR  G+ +LP+RWMA E +  G FTT SDVW+FGV
Sbjct: 1121 CMVSQDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGV 1180

Query: 838  TLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRE 897
             LWE++ L   QP+  L++EQV+    +F  D G    L     CP  L ELM RCW   
Sbjct: 1181 VLWEIVTLAE-QPYQGLSNEQVL----KFVMDGG---VLEELEGCPLQLQELMSRCWQPN 1232

Query: 898  SEQRPPFSQLHRFLAED 914
               RP F+ +   + E+
Sbjct: 1233 PRLRPSFTHILDSIQEE 1249


>gi|19743898 receptor tyrosine kinase-like orphan receptor 2
           precursor [Homo sapiens]
          Length = 943

 Score =  191 bits (486), Expect = 2e-48
 Identities = 112/301 (37%), Positives = 166/301 (55%), Gaps = 28/301 (9%)

Query: 608 SRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNASF 667
           S +RF E+LGE +FG+V+   +  P                   VA+K L+  A      
Sbjct: 471 SAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQ-----------AVAIKTLKDKAEGPL-- 517

Query: 668 SLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDK 727
               R +F  E  + +RL+ PN++ LLGV  +D PL MI  Y  +GDL++FL        
Sbjct: 518 ----REEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSD 573

Query: 728 AAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIK 787
              G+  D +  +   +  P  +H+ AQIA+GM YL++ + VH+DLATRN LV +   +K
Sbjct: 574 V--GSTDDDRTVKS-ALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVK 630

Query: 788 IADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCR 847
           I+D G+ R +YA DYY++ G ++LPIRWMA E I+ GKF+  SD+W++GV LWEV     
Sbjct: 631 ISDLGLFREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSY-G 689

Query: 848 AQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQL 907
            QP+   +++ V+E        + RQV L  P  CP  +Y LM+ CW+    +RP F  +
Sbjct: 690 LQPYCGYSNQDVVEMI------RNRQV-LPCPDDCPAWVYALMIECWNEFPSRRPRFKDI 742

Query: 908 H 908
           H
Sbjct: 743 H 743


>gi|19924165 proto-oncogene c-ros-1 protein precursor [Homo sapiens]
          Length = 2347

 Score =  191 bits (486), Expect = 2e-48
 Identities = 121/347 (34%), Positives = 188/347 (54%), Gaps = 48/347 (13%)

Query: 571  EADIVTLQGVTGG-----NTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVH 625
            + ++  L+G+  G       YA+  LP     +  P   FPR +L  +  LG G FGEV+
Sbjct: 1903 DKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPA--FPREKLTLRLLLGSGAFGEVY 1960

Query: 626  LCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNASFSLFSRNDFLKEVKIMSRL 685
                    +  ++D  L V  G  + VAVK L+  +T           +FLKE  +MS+ 
Sbjct: 1961 --------EGTAVDI-LGVGSGE-IKVAVKTLKKGSTDQEKI------EFLKEAHLMSKF 2004

Query: 686  KDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTIS 745
              PNI++ LGVC+ ++P  +I + ME GDL  +L   ++                GP ++
Sbjct: 2005 NHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMA------------TFYGPLLT 2052

Query: 746  YPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVG-ENFT----IKIADFGMSRNLYAG 800
               L+ +   I+ G  YL  ++F+HRDLA RNCLV  +++T    +KI DFG++R++Y  
Sbjct: 2053 LVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKN 2112

Query: 801  DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVI 860
            DYYR +G  +LP+RWMA E ++ G FTT SDVW+FG+ +WE+L L   QP+   ++  V+
Sbjct: 2113 DYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGH-QPYPAHSNLDVL 2171

Query: 861  ENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQL 907
                 + +  GR   L  P  CP  L+ LM +CW++E +QRP F ++
Sbjct: 2172 ----NYVQTGGR---LEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRI 2211


>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
           [Homo sapiens]
          Length = 1130

 Score =  191 bits (484), Expect = 4e-48
 Identities = 112/306 (36%), Positives = 160/306 (52%), Gaps = 50/306 (16%)

Query: 604 DFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATK 663
           +  R+ +  K KLG GQ+GEV+                  V K + L VAVK L+ D  +
Sbjct: 236 EMERTDITMKHKLGGGQYGEVYE----------------GVWKKYSLTVAVKTLKEDTME 279

Query: 664 NASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQ 723
                     +FLKE  +M  +K PN+++LLGVC ++ P  +IT++M  G+L  +L    
Sbjct: 280 V--------EEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECN 331

Query: 724 LEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGEN 783
            ++                 ++  +LL++A QI+S M YL   NF+HRDLA RNCLVGEN
Sbjct: 332 RQE-----------------VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN 374

Query: 784 FTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVL 843
             +K+ADFG+SR L  GD Y     A  PI+W A E +   KF+  SDVWAFGV LWE+ 
Sbjct: 375 HLVKVADFGLSR-LMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIA 433

Query: 844 MLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPP 903
                 P+  +   QV E   + +R       + RP  CP+ +YELM  CW      RP 
Sbjct: 434 TY-GMSPYPGIDLSQVYELLEKDYR-------MERPEGCPEKVYELMRACWQWNPSDRPS 485

Query: 904 FSQLHR 909
           F+++H+
Sbjct: 486 FAEIHQ 491


>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
           [Homo sapiens]
          Length = 1149

 Score =  191 bits (484), Expect = 4e-48
 Identities = 112/306 (36%), Positives = 160/306 (52%), Gaps = 50/306 (16%)

Query: 604 DFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATK 663
           +  R+ +  K KLG GQ+GEV+                  V K + L VAVK L+ D  +
Sbjct: 255 EMERTDITMKHKLGGGQYGEVYE----------------GVWKKYSLTVAVKTLKEDTME 298

Query: 664 NASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQ 723
                     +FLKE  +M  +K PN+++LLGVC ++ P  +IT++M  G+L  +L    
Sbjct: 299 V--------EEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECN 350

Query: 724 LEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGEN 783
            ++                 ++  +LL++A QI+S M YL   NF+HRDLA RNCLVGEN
Sbjct: 351 RQE-----------------VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN 393

Query: 784 FTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVL 843
             +K+ADFG+SR L  GD Y     A  PI+W A E +   KF+  SDVWAFGV LWE+ 
Sbjct: 394 HLVKVADFGLSR-LMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIA 452

Query: 844 MLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPP 903
                 P+  +   QV E   + +R       + RP  CP+ +YELM  CW      RP 
Sbjct: 453 TY-GMSPYPGIDLSQVYELLEKDYR-------MERPEGCPEKVYELMRACWQWNPSDRPS 504

Query: 904 FSQLHR 909
           F+++H+
Sbjct: 505 FAEIHQ 510


>gi|4557665 insulin-like growth factor 1 receptor precursor [Homo
            sapiens]
          Length = 1367

 Score =  189 bits (480), Expect = 1e-47
 Identities = 116/318 (36%), Positives = 167/318 (52%), Gaps = 40/318 (12%)

Query: 600  PPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRP 659
            P   +  R ++    +LG+G FG V+    +     V  D P          VA+K    
Sbjct: 989  PDEWEVAREKITMSRELGQGSFGMVY----EGVAKGVVKDEP-------ETRVAIK---- 1033

Query: 660  DATKNASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFL 719
              T N + S+  R +FL E  +M      +++RLLGV  Q  P  +I + M  GDL  +L
Sbjct: 1034 --TVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYL 1091

Query: 720  SAHQLEDKAAEGAPGDGQAAQGPTISYPML---LHVAAQIASGMRYLATLNFVHRDLATR 776
             + + E +              P ++ P L   + +A +IA GM YL    FVHRDLA R
Sbjct: 1092 RSLRPEME------------NNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAAR 1139

Query: 777  NCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFG 836
            NC+V E+FT+KI DFGM+R++Y  DYYR  G+ +LP+RWM+ E +  G FTT SDVW+FG
Sbjct: 1140 NCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFG 1199

Query: 837  VTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSR 896
            V LWE+  L   QP+  L++EQV+     F  + G    L +P  CP  L+ELM  CW  
Sbjct: 1200 VVLWEIATLAE-QPYQGLSNEQVL----RFVMEGG---LLDKPDNCPDMLFELMRMCWQY 1251

Query: 897  ESEQRPPFSQLHRFLAED 914
              + RP F ++   + E+
Sbjct: 1252 NPKMRPSFLEIISSIKEE 1269


>gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]
          Length = 1167

 Score =  186 bits (472), Expect = 9e-47
 Identities = 111/306 (36%), Positives = 156/306 (50%), Gaps = 50/306 (16%)

Query: 604 DFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATK 663
           +  R+ +  K KLG GQ+GEV++                 V K + L VAVK L+ D  +
Sbjct: 267 EMERTDITMKHKLGGGQYGEVYV----------------GVWKKYSLTVAVKTLKEDTME 310

Query: 664 NASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQ 723
                     +FLKE  +M  +K PN+++LLGVC  + P  ++T+YM  G+L  +L    
Sbjct: 311 V--------EEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECN 362

Query: 724 LEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGEN 783
            E+  A                  +LL++A QI+S M YL   NF+HRDLA RNCLVGEN
Sbjct: 363 REEVTAV-----------------VLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN 405

Query: 784 FTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVL 843
             +K+ADFG+SR L  GD Y     A  PI+W A E +    F+  SDVWAFGV LWE+ 
Sbjct: 406 HVVKVADFGLSR-LMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIA 464

Query: 844 MLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPP 903
                 P+  +   QV +   + +R       + +P  CP  +YELM  CW      RP 
Sbjct: 465 TY-GMSPYPGIDLSQVYDLLEKGYR-------MEQPEGCPPKVYELMRACWKWSPADRPS 516

Query: 904 FSQLHR 909
           F++ H+
Sbjct: 517 FAETHQ 522


>gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]
          Length = 1182

 Score =  186 bits (472), Expect = 9e-47
 Identities = 111/306 (36%), Positives = 156/306 (50%), Gaps = 50/306 (16%)

Query: 604 DFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATK 663
           +  R+ +  K KLG GQ+GEV++                 V K + L VAVK L+ D  +
Sbjct: 282 EMERTDITMKHKLGGGQYGEVYV----------------GVWKKYSLTVAVKTLKEDTME 325

Query: 664 NASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQ 723
                     +FLKE  +M  +K PN+++LLGVC  + P  ++T+YM  G+L  +L    
Sbjct: 326 V--------EEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECN 377

Query: 724 LEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGEN 783
            E+  A                  +LL++A QI+S M YL   NF+HRDLA RNCLVGEN
Sbjct: 378 REEVTAV-----------------VLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN 420

Query: 784 FTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVL 843
             +K+ADFG+SR L  GD Y     A  PI+W A E +    F+  SDVWAFGV LWE+ 
Sbjct: 421 HVVKVADFGLSR-LMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIA 479

Query: 844 MLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPP 903
                 P+  +   QV +   + +R       + +P  CP  +YELM  CW      RP 
Sbjct: 480 TY-GMSPYPGIDLSQVYDLLEKGYR-------MEQPEGCPPKVYELMRACWKWSPADRPS 531

Query: 904 FSQLHR 909
           F++ H+
Sbjct: 532 FAETHQ 537


>gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]
          Length = 542

 Score =  186 bits (472), Expect = 9e-47
 Identities = 111/306 (36%), Positives = 156/306 (50%), Gaps = 50/306 (16%)

Query: 604 DFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATK 663
           +  R+ +  K KLG GQ+GEV++                 V K + L VAVK L+ D  +
Sbjct: 261 EMERTDITMKHKLGGGQYGEVYV----------------GVWKKYSLTVAVKTLKEDTME 304

Query: 664 NASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQ 723
                     +FLKE  +M  +K PN+++LLGVC  + P  ++T+YM  G+L  +L    
Sbjct: 305 V--------EEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECN 356

Query: 724 LEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGEN 783
            E+  A                  +LL++A QI+S M YL   NF+HRDLA RNCLVGEN
Sbjct: 357 REEVTAV-----------------VLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN 399

Query: 784 FTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVL 843
             +K+ADFG+SR L  GD Y     A  PI+W A E +    F+  SDVWAFGV LWE+ 
Sbjct: 400 HVVKVADFGLSR-LMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIA 458

Query: 844 MLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPP 903
                 P+  +   QV +   + +R       + +P  CP  +YELM  CW      RP 
Sbjct: 459 TY-GMSPYPGIDLSQVYDLLEKGYR-------MEQPEGCPPKVYELMRACWKWSPADRPS 510

Query: 904 FSQLHR 909
           F++ H+
Sbjct: 511 FAETHQ 516


>gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]
          Length = 1064

 Score =  186 bits (472), Expect = 9e-47
 Identities = 111/306 (36%), Positives = 156/306 (50%), Gaps = 50/306 (16%)

Query: 604 DFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATK 663
           +  R+ +  K KLG GQ+GEV++                 V K + L VAVK L+ D  +
Sbjct: 267 EMERTDITMKHKLGGGQYGEVYV----------------GVWKKYSLTVAVKTLKEDTME 310

Query: 664 NASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQ 723
                     +FLKE  +M  +K PN+++LLGVC  + P  ++T+YM  G+L  +L    
Sbjct: 311 V--------EEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECN 362

Query: 724 LEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGEN 783
            E+  A                  +LL++A QI+S M YL   NF+HRDLA RNCLVGEN
Sbjct: 363 REEVTAV-----------------VLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN 405

Query: 784 FTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVL 843
             +K+ADFG+SR L  GD Y     A  PI+W A E +    F+  SDVWAFGV LWE+ 
Sbjct: 406 HVVKVADFGLSR-LMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIA 464

Query: 844 MLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPP 903
                 P+  +   QV +   + +R       + +P  CP  +YELM  CW      RP 
Sbjct: 465 TY-GMSPYPGIDLSQVYDLLEKGYR-------MEQPEGCPPKVYELMRACWKWSPADRPS 516

Query: 904 FSQLHR 909
           F++ H+
Sbjct: 517 FAETHQ 522


>gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]
          Length = 1146

 Score =  186 bits (472), Expect = 9e-47
 Identities = 111/306 (36%), Positives = 156/306 (50%), Gaps = 50/306 (16%)

Query: 604 DFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATK 663
           +  R+ +  K KLG GQ+GEV++                 V K + L VAVK L+ D  +
Sbjct: 246 EMERTDITMKHKLGGGQYGEVYV----------------GVWKKYSLTVAVKTLKEDTME 289

Query: 664 NASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQ 723
                     +FLKE  +M  +K PN+++LLGVC  + P  ++T+YM  G+L  +L    
Sbjct: 290 V--------EEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECN 341

Query: 724 LEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGEN 783
            E+  A                  +LL++A QI+S M YL   NF+HRDLA RNCLVGEN
Sbjct: 342 REEVTAV-----------------VLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN 384

Query: 784 FTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVL 843
             +K+ADFG+SR L  GD Y     A  PI+W A E +    F+  SDVWAFGV LWE+ 
Sbjct: 385 HVVKVADFGLSR-LMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIA 443

Query: 844 MLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPP 903
                 P+  +   QV +   + +R       + +P  CP  +YELM  CW      RP 
Sbjct: 444 TY-GMSPYPGIDLSQVYDLLEKGYR-------MEQPEGCPPKVYELMRACWKWSPADRPS 495

Query: 904 FSQLHR 909
           F++ H+
Sbjct: 496 FAETHQ 501


>gi|47524177 fibroblast growth factor receptor 4 isoform 2 precursor
           [Homo sapiens]
          Length = 762

 Score =  184 bits (468), Expect = 3e-46
 Identities = 121/322 (37%), Positives = 172/322 (53%), Gaps = 28/322 (8%)

Query: 589 PALPPGAVG-DGP--PRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVR 645
           PAL  G V  D P  P  +FPR RL   + LGEG FG+V   E                R
Sbjct: 403 PALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDP---------AR 453

Query: 646 KGHPLLVAVKILRPDATKNASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCM 705
                 VAVK+L+ +A+      L S    ++ +K++ R K  NII LLGVC Q+ PL +
Sbjct: 454 PDQASTVAVKMLKDNASDKDLADLVSE---MEVMKLIGRHK--NIINLLGVCTQEGPLYV 508

Query: 706 ITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLAT 765
           I +    G+L +FL A +      + +P   ++++GP +S+P+L+  A Q+A GM+YL +
Sbjct: 509 IVECAAKGNLREFLRARR--PPGPDLSPDGPRSSEGP-LSFPVLVSCAYQVARGMQYLES 565

Query: 766 LNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGK 825
              +HRDLA RN LV E+  +KIADFG++R ++  DYY+      LP++WMA E +    
Sbjct: 566 RKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRV 625

Query: 826 FTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQG 885
           +T  SDVW+FG+ LWE+  L    P+  +  E++     E  R       + RPP CP  
Sbjct: 626 YTHQSDVWSFGILLWEIFTL-GGSPYPGIPVEELFSLLREGHR-------MDRPPHCPPE 677

Query: 886 LYELMLRCWSRESEQRPPFSQL 907
           LY LM  CW     QRP F QL
Sbjct: 678 LYGLMRECWHAAPSQRPTFKQL 699


>gi|47524175 fibroblast growth factor receptor 4 isoform 1 precursor
           [Homo sapiens]
          Length = 802

 Score =  184 bits (468), Expect = 3e-46
 Identities = 121/322 (37%), Positives = 172/322 (53%), Gaps = 28/322 (8%)

Query: 589 PALPPGAVG-DGP--PRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVR 645
           PAL  G V  D P  P  +FPR RL   + LGEG FG+V   E                R
Sbjct: 443 PALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDP---------AR 493

Query: 646 KGHPLLVAVKILRPDATKNASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCM 705
                 VAVK+L+ +A+      L S    ++ +K++ R K  NII LLGVC Q+ PL +
Sbjct: 494 PDQASTVAVKMLKDNASDKDLADLVSE---MEVMKLIGRHK--NIINLLGVCTQEGPLYV 548

Query: 706 ITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLAT 765
           I +    G+L +FL A +      + +P   ++++GP +S+P+L+  A Q+A GM+YL +
Sbjct: 549 IVECAAKGNLREFLRARR--PPGPDLSPDGPRSSEGP-LSFPVLVSCAYQVARGMQYLES 605

Query: 766 LNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGK 825
              +HRDLA RN LV E+  +KIADFG++R ++  DYY+      LP++WMA E +    
Sbjct: 606 RKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRV 665

Query: 826 FTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQG 885
           +T  SDVW+FG+ LWE+  L    P+  +  E++     E  R       + RPP CP  
Sbjct: 666 YTHQSDVWSFGILLWEIFTL-GGSPYPGIPVEELFSLLREGHR-------MDRPPHCPPE 717

Query: 886 LYELMLRCWSRESEQRPPFSQL 907
           LY LM  CW     QRP F QL
Sbjct: 718 LYGLMRECWHAAPSQRPTFKQL 739


>gi|47524173 fibroblast growth factor receptor 4 isoform 1 precursor
           [Homo sapiens]
          Length = 802

 Score =  184 bits (468), Expect = 3e-46
 Identities = 121/322 (37%), Positives = 172/322 (53%), Gaps = 28/322 (8%)

Query: 589 PALPPGAVG-DGP--PRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVR 645
           PAL  G V  D P  P  +FPR RL   + LGEG FG+V   E                R
Sbjct: 443 PALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDP---------AR 493

Query: 646 KGHPLLVAVKILRPDATKNASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCM 705
                 VAVK+L+ +A+      L S    ++ +K++ R K  NII LLGVC Q+ PL +
Sbjct: 494 PDQASTVAVKMLKDNASDKDLADLVSE---MEVMKLIGRHK--NIINLLGVCTQEGPLYV 548

Query: 706 ITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLAT 765
           I +    G+L +FL A +      + +P   ++++GP +S+P+L+  A Q+A GM+YL +
Sbjct: 549 IVECAAKGNLREFLRARR--PPGPDLSPDGPRSSEGP-LSFPVLVSCAYQVARGMQYLES 605

Query: 766 LNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGK 825
              +HRDLA RN LV E+  +KIADFG++R ++  DYY+      LP++WMA E +    
Sbjct: 606 RKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRV 665

Query: 826 FTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQG 885
           +T  SDVW+FG+ LWE+  L    P+  +  E++     E  R       + RPP CP  
Sbjct: 666 YTHQSDVWSFGILLWEIFTL-GGSPYPGIPVEELFSLLREGHR-------MDRPPHCPPE 717

Query: 886 LYELMLRCWSRESEQRPPFSQL 907
           LY LM  CW     QRP F QL
Sbjct: 718 LYGLMRECWHAAPSQRPTFKQL 739


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,011,963
Number of Sequences: 37866
Number of extensions: 2567929
Number of successful extensions: 16662
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 594
Number of HSP's successfully gapped in prelim test: 623
Number of HSP's that attempted gapping in prelim test: 11459
Number of HSP's gapped (non-prelim): 4164
length of query: 919
length of database: 18,247,518
effective HSP length: 111
effective length of query: 808
effective length of database: 14,044,392
effective search space: 11347868736
effective search space used: 11347868736
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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