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Search of human proteins with 8393516
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
(373 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo s... 756 0.0
gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sap... 756 0.0
gi|116268111 short chain dehydrogenase/reductase family 42E, mem... 174 2e-43
gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family pr... 145 4e-35
gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo ... 145 4e-35
gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo ... 145 4e-35
gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s... 125 5e-29
gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens] 113 2e-25
gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 105 9e-23
gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens] 71 2e-12
gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ... 65 8e-11
gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ... 65 8e-11
gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens] 50 3e-06
gi|56118217 UDP-galactose-4-epimerase [Homo sapiens] 45 8e-05
gi|56237023 UDP-galactose-4-epimerase [Homo sapiens] 45 8e-05
gi|189083684 UDP-galactose-4-epimerase [Homo sapiens] 45 8e-05
gi|33519455 methionine adenosyltransferase II, beta isoform 2 [H... 39 0.008
gi|11034825 methionine adenosyltransferase II, beta isoform 1 [H... 37 0.037
gi|169163903 PREDICTED: hypothetical protein [Homo sapiens] 32 0.71
gi|239747712 PREDICTED: hypothetical protein XP_002348233 [Homo ... 32 0.71
gi|6681764 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9... 32 0.71
gi|40068481 SET domain containing 3 isoform a [Homo sapiens] 32 1.2
gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens] 30 3.5
gi|239741578 PREDICTED: hypothetical protein XP_002342256 [Homo ... 30 3.5
gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens] 30 3.5
gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens] 30 3.5
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 30 4.6
gi|115430219 lambda-crystallin [Homo sapiens] 30 4.6
gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens] 29 6.0
gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens] 29 6.0
>gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
Length = 373
Score = 756 bits (1952), Expect = 0.0
Identities = 373/373 (100%), Positives = 373/373 (100%)
Query: 1 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR 60
MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR
Sbjct: 1 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR 60
Query: 61 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV 120
GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV
Sbjct: 61 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV 120
Query: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE 180
NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE
Sbjct: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE 180
Query: 181 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV 240
RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV
Sbjct: 181 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV 240
Query: 241 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA 300
ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA
Sbjct: 241 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA 300
Query: 301 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME 360
YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME
Sbjct: 301 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME 360
Query: 361 RTVQSFRHLRRVK 373
RTVQSFRHLRRVK
Sbjct: 361 RTVQSFRHLRRVK 373
>gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
Length = 373
Score = 756 bits (1952), Expect = 0.0
Identities = 373/373 (100%), Positives = 373/373 (100%)
Query: 1 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR 60
MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR
Sbjct: 1 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR 60
Query: 61 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV 120
GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV
Sbjct: 61 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV 120
Query: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE 180
NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE
Sbjct: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE 180
Query: 181 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV 240
RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV
Sbjct: 181 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV 240
Query: 241 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA 300
ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA
Sbjct: 241 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA 300
Query: 301 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME 360
YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME
Sbjct: 301 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME 360
Query: 361 RTVQSFRHLRRVK 373
RTVQSFRHLRRVK
Sbjct: 361 RTVQSFRHLRRVK 373
>gi|116268111 short chain dehydrogenase/reductase family 42E, member
1 [Homo sapiens]
Length = 393
Score = 174 bits (440), Expect = 2e-43
Identities = 110/333 (33%), Positives = 172/333 (51%), Gaps = 16/333 (4%)
Query: 34 QNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN-PQ-VRFFLGDLCSRQDL 91
++Q + + GGSG+ G + L G V +FDI P+ ++F GD+ D+
Sbjct: 5 RSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLSDV 64
Query: 92 YPALKG--VNTVFHCASPPPSSN---NKELFYRVNYIGTKNVIETCKEAGVQKLILTSSA 146
A + V VFH AS S N+ L VN GT N+++ C+ V +L+ TS+
Sbjct: 65 EKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTF 124
Query: 147 SVIFEGVDIKNGTEDLPYAMKPI--DYYTETKILQERAVLGANDPEKN-----FLTTAIR 199
+VIF G I+NG E LPY + D+Y+ TK + E+ VL AN + T A+R
Sbjct: 125 NVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTCALR 184
Query: 200 PHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDS- 258
P GI+GP + + +P ++ G KFV G+ ++LV+F V+N+V HILA+E L D
Sbjct: 185 PAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRADKG 244
Query: 259 -TLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPV 317
G+ + I++ P+ + F ++ GL Y P +P + Y A L ++ ++ +
Sbjct: 245 HIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFILGRL 304
Query: 318 IQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQ 350
QP T V G HY+S E+AKK +GY+
Sbjct: 305 YNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYK 337
>gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family
protein ENSP00000330812 [Homo sapiens]
Length = 422
Score = 145 bits (367), Expect = 4e-35
Identities = 109/375 (29%), Positives = 176/375 (46%), Gaps = 16/375 (4%)
Query: 6 SEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVN 65
S P R + P+ K + ++ V GG G+LG + L G +V
Sbjct: 3 SNPPRSSLEACKAAGQAPQQKTQA-KPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVI 61
Query: 66 VFDIQ--QGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNK---ELFYRV 120
+ D + Q +P+ +F D+ + LY A +GV+ VFH AS S K E +
Sbjct: 62 LLDRRRPQWELSPETKFIQADVRDEEALYHAFEGVDCVFHVASYGMSGAEKLQKEQIESI 121
Query: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTED-LPYAM--KPIDYYTETKI 177
N GTK VI+ C V +LI TS+ +V F G I+ G ED +PY + +D+Y+ TK
Sbjct: 122 NVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKA 181
Query: 178 LQERAVLGAND---PEKNFLTTAI-RPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKN 233
+ ++ L AN P L T + RP GI+GP + + +P + + F G+ K
Sbjct: 182 IADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKA 241
Query: 234 LVDFTFVENVVHGHILAAEQLS--RDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAP 291
+++ V N+V H+LAAE L+ + G+A++I + E + + +++ + L Y P
Sbjct: 242 RMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQP 301
Query: 292 KYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQP 351
+P Y A ++ L + + P+ L P T V H + +A+ +GY P
Sbjct: 302 WIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361
Query: 352 -LVTMDDAMERTVQS 365
DA+E VQS
Sbjct: 362 DKFRFADAVELYVQS 376
>gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo
sapiens]
Length = 422
Score = 145 bits (367), Expect = 4e-35
Identities = 109/375 (29%), Positives = 176/375 (46%), Gaps = 16/375 (4%)
Query: 6 SEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVN 65
S P R + P+ K + ++ V GG G+LG + L G +V
Sbjct: 3 SNPPRSSLEACKAAGQAPQQKTQA-KPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVI 61
Query: 66 VFDIQ--QGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNK---ELFYRV 120
+ D + Q +P+ +F D+ + LY A +GV+ VFH AS S K E +
Sbjct: 62 LLDRRRPQWELSPETKFIQADVRDEEALYHAFEGVDCVFHVASYGMSGAEKLQKEQIESI 121
Query: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTED-LPYAM--KPIDYYTETKI 177
N GTK VI+ C V +LI TS+ +V F G I+ G ED +PY + +D+Y+ TK
Sbjct: 122 NVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKA 181
Query: 178 LQERAVLGAND---PEKNFLTTAI-RPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKN 233
+ ++ L AN P L T + RP GI+GP + + +P + + F G+ K
Sbjct: 182 IADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKA 241
Query: 234 LVDFTFVENVVHGHILAAEQLS--RDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAP 291
+++ V N+V H+LAAE L+ + G+A++I + E + + +++ + L Y P
Sbjct: 242 RMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQP 301
Query: 292 KYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQP 351
+P Y A ++ L + + P+ L P T V H + +A+ +GY P
Sbjct: 302 WIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361
Query: 352 -LVTMDDAMERTVQS 365
DA+E VQS
Sbjct: 362 DKFRFADAVELYVQS 376
>gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo
sapiens]
Length = 422
Score = 145 bits (367), Expect = 4e-35
Identities = 109/375 (29%), Positives = 176/375 (46%), Gaps = 16/375 (4%)
Query: 6 SEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVN 65
S P R + P+ K + ++ V GG G+LG + L G +V
Sbjct: 3 SNPPRSSLEACKAAGQAPQQKTQA-KPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVI 61
Query: 66 VFDIQ--QGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNK---ELFYRV 120
+ D + Q +P+ +F D+ + LY A +GV+ VFH AS S K E +
Sbjct: 62 LLDRRRPQWELSPETKFIQADVRDEEALYRAFEGVDCVFHVASYGMSGAEKLQKEQIESI 121
Query: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTED-LPYAM--KPIDYYTETKI 177
N GTK VI+ C V +LI TS+ +V F G I+ G ED +PY + +D+Y+ TK
Sbjct: 122 NVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKA 181
Query: 178 LQERAVLGAND---PEKNFLTTAI-RPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKN 233
+ ++ L AN P L T + RP GI+GP + + +P + + F G+ K
Sbjct: 182 IADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKA 241
Query: 234 LVDFTFVENVVHGHILAAEQLS--RDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAP 291
+++ V N+V H+LAAE L+ + G+A++I + E + + +++ + L Y P
Sbjct: 242 RMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQP 301
Query: 292 KYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQP 351
+P Y A ++ L + + P+ L P T V H + +A+ +GY P
Sbjct: 302 WIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361
Query: 352 -LVTMDDAMERTVQS 365
DA+E VQS
Sbjct: 362 DKFRFADAVELYVQS 376
>gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
steroid delta-isomerase 7 isoform a [Homo sapiens]
Length = 369
Score = 125 bits (315), Expect = 5e-29
Identities = 103/345 (29%), Positives = 157/345 (45%), Gaps = 23/345 (6%)
Query: 42 VIGGSGFLGQHMVEQLLARGYAVN---VFDIQQG-------FDNPQVRFFLGDLCSRQDL 91
V GG GFLG+H+V LL R + VFD G +V GD+ ++
Sbjct: 14 VTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTAIQGDVTQAHEV 73
Query: 92 YPALKGVNTVFHCASPPP--SSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI 149
A+ G + V H A + + + VN GT+NVIE C + G + L+ TSS V+
Sbjct: 74 AAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVV 133
Query: 150 ---FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKN----FLTTAIRPHG 202
+G G ED PY Y +K L E VL AN + +T A+RP G
Sbjct: 134 GPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRGGLPLVTCALRPTG 193
Query: 203 IFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDSTL-G 261
I+G + + R G F +V NV H+LAA +L + +TL G
Sbjct: 194 IYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVLAARELEQRATLMG 253
Query: 262 GKAFHITNDEPI-PFWTFLSRIL--TGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVI 318
G+ + + P + F L GL + +PYW+ +LA L +LL ++ P++
Sbjct: 254 GQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLLVFLAALNALLQWLLRPLV 313
Query: 319 QLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTV 363
P P +A+A T S ++A++ GY+PL + +D+ RT+
Sbjct: 314 LYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRTRTI 358
>gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens]
Length = 372
Score = 113 bits (283), Expect = 2e-25
Identities = 99/354 (27%), Positives = 168/354 (47%), Gaps = 33/354 (9%)
Query: 40 CTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVR-------------FFLGDLC 86
C V G G LGQ +V L+ + + + F P++R GD+
Sbjct: 5 CLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAF-RPELREEFSKLQNRTKLTVLEGDIL 63
Query: 87 SRQDLYPALKGVNTVFH--CASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTS 144
L A + V+ V H C ++E VN GT+ ++E C +A V I TS
Sbjct: 64 DEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 123
Query: 145 SASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE-KN---FLTT 196
S V ++ + I+NG E+ P Y +K L E+AVL AN KN T
Sbjct: 124 SIEVAGPNSYKEI-IQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLYTC 182
Query: 197 AIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQL-- 254
A+RP I+G P L + EA N + +G V+ +V NV HILA L
Sbjct: 183 ALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFST-VNPVYVGNVAWAHILALRALRD 241
Query: 255 -SRDSTLGGKAFHITNDEPIPFWTFLSRILT---GLNYEAPKYHIPYWVAYYLALLLSLL 310
+ ++ G+ ++I++D P + L+ IL+ GL ++ ++ +P + Y++ LL ++
Sbjct: 242 PKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDS-RWSLPLTLMYWIGFLLEVV 300
Query: 311 VMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTVQ 364
++SP+ QP F V L+ + +S ++A++ + Y+PL + ++A ++TV+
Sbjct: 301 SFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVE 354
>gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
Length = 373
Score = 105 bits (261), Expect = 9e-23
Identities = 94/354 (26%), Positives = 165/354 (46%), Gaps = 33/354 (9%)
Query: 40 CTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVR-------------FFLGDLC 86
C V G GFLGQ ++ L+ + + + F P++R GD+
Sbjct: 6 CLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAF-GPELREEFSKLQNKTKLTVLEGDIL 64
Query: 87 SRQDLYPALKGVNTVFH--CASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTS 144
L A + V+ + H C ++E VN GT+ ++E C +A V I TS
Sbjct: 65 DEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 124
Query: 145 SASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE-KN---FLTT 196
S V ++ + I+NG E+ P Y +K L E+AVL AN KN T
Sbjct: 125 SIEVAGPNSYKEI-IQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTLYTC 183
Query: 197 AIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLS- 255
A+RP I+G L + EA N + +G V+ +V NV HILA L
Sbjct: 184 ALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFST-VNPVYVGNVAWAHILALRALQD 242
Query: 256 --RDSTLGGKAFHITNDEPIPFWTFLSRILT---GLNYEAPKYHIPYWVAYYLALLLSLL 310
+ ++ G+ ++I++D P + L+ L+ GL ++ ++ P + Y++ LL ++
Sbjct: 243 PKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDS-RWSFPLSLMYWIGFLLEIV 301
Query: 311 VMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTVQ 364
++ P+ +P F V L+ + +S ++A++ + Y+PL + ++A ++TV+
Sbjct: 302 SFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVE 355
>gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens]
Length = 420
Score = 70.9 bits (172), Expect = 2e-12
Identities = 69/275 (25%), Positives = 122/275 (44%), Gaps = 20/275 (7%)
Query: 7 EPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNV 66
EP+R+++ L + + ++ +++ KR + GG+GF+G H+ ++L+ G+ V V
Sbjct: 60 EPLREKIR--DLEKSFTQKYPPVKFLSEKDRKRILITGGAGFVGSHLTDKLMMDGHEVTV 117
Query: 67 FDIQQGFDNPQVRFFLG----DLCSRQDLYPALKGVNTVFHCASPPPSSN---NKELFYR 119
D V ++G +L + + P V+ ++H ASP N N +
Sbjct: 118 VDNFFTGRKRNVEHWIGHENFELINHDVVEPLYIEVDQIYHLASPASPPNYMYNPIKTLK 177
Query: 120 VNYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPID---YYTETK 176
N IGT N++ K G + +L +S S ++ ++ +ED + PI Y E K
Sbjct: 178 TNTIGTLNMLGLAKRVGAR--LLLASTSEVYGDPEVHPQSEDYWGHVNPIGPRACYDEGK 235
Query: 177 ILQERAVLGANDPEKNFLTTAIRPHGIFGPR----DPQLVPILIEAARNGKMKFVIGNGK 232
+ E + A ++ R FGPR D ++V I A G+ V G+G
Sbjct: 236 RVAE-TMCYAYMKQEGVEVRVARIFNTFGPRMHMNDGRVVSNFILQALQGEPLTVYGSGS 294
Query: 233 NLVDFTFVENVVHGHI-LAAEQLSRDSTLGGKAFH 266
F +V ++V+G + L +S LG H
Sbjct: 295 QTRAFQYVSDLVNGLVALMNSNVSSPVNLGNPEEH 329
>gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
steroid delta-isomerase 7 isoform b [Homo sapiens]
Length = 196
Score = 65.5 bits (158), Expect = 8e-11
Identities = 53/161 (32%), Positives = 72/161 (44%), Gaps = 15/161 (9%)
Query: 42 VIGGSGFLGQHMVEQLLARGYAVN---VFDIQQG-------FDNPQVRFFLGDLCSRQDL 91
V GG GFLG+H+V LL R + VFD G +V GD+ ++
Sbjct: 14 VTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTAIQGDVTQAHEV 73
Query: 92 YPALKGVNTVFHCASPPP--SSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI 149
A+ G + V H A + + + VN GT+NVIE C + G + L+ TSS V+
Sbjct: 74 AAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVV 133
Query: 150 ---FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGAN 187
+G G ED PY Y +K L E VL AN
Sbjct: 134 GPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEAN 174
>gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
steroid delta-isomerase 7 isoform b [Homo sapiens]
Length = 196
Score = 65.5 bits (158), Expect = 8e-11
Identities = 53/161 (32%), Positives = 72/161 (44%), Gaps = 15/161 (9%)
Query: 42 VIGGSGFLGQHMVEQLLARGYAVN---VFDIQQG-------FDNPQVRFFLGDLCSRQDL 91
V GG GFLG+H+V LL R + VFD G +V GD+ ++
Sbjct: 14 VTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTAIQGDVTQAHEV 73
Query: 92 YPALKGVNTVFHCASPPP--SSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI 149
A+ G + V H A + + + VN GT+NVIE C + G + L+ TSS V+
Sbjct: 74 AAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVV 133
Query: 150 ---FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGAN 187
+G G ED PY Y +K L E VL AN
Sbjct: 134 GPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEAN 174
>gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens]
Length = 350
Score = 50.4 bits (119), Expect = 3e-06
Identities = 54/231 (23%), Positives = 93/231 (40%), Gaps = 23/231 (9%)
Query: 37 AKRCTVIGGSGFLGQHMVEQLL------------ARGYAVNVFDIQQGFDNPQVRFFLGD 84
AKR V GG+GF+ HM+ L+ Y ++ +++ + +F GD
Sbjct: 17 AKRVLVTGGAGFIASHMIVSLVEDYPNYMIINLDKLDYCASLKNLETISNKQNYKFIQGD 76
Query: 85 LCSRQ--DLYPALKGVNTVFHCASPPP---SSNNKELFYRVNYIGTKNVIETCKEAGVQK 139
+C L + ++ V H A+ S F VN GT ++ EA V+K
Sbjct: 77 ICDSHFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSAAHEARVEK 136
Query: 140 LILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKNFLTTAIR 199
I S+ V +D K E P +P + Y +K E V + K F R
Sbjct: 137 FIYVSTDEVYGGSLD-KEFDESSP--KQPTNPYASSKAAAECFVQSYWEQYK-FPVVITR 192
Query: 200 PHGIFGPRD--PQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHI 248
++GP +++P I ++ + + G+G +F + +VV +
Sbjct: 193 SSNVYGPHQYPEKVIPKFISLLQHNRKCCIHGSGLQTRNFLYATDVVEAFL 243
>gi|56118217 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 45.4 bits (106), Expect = 8e-05
Identities = 70/264 (26%), Positives = 104/264 (39%), Gaps = 53/264 (20%)
Query: 37 AKRCTVIGGSGFLGQHMVEQLLARGYAVNVFD-----IQQGFDNPQ------------VR 79
A++ V GG+G++G H V +LL GY V D + G P+ V
Sbjct: 2 AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVE 61
Query: 80 FFLGDLCSRQDLYPALKGVN--TVFHCASPPP--SSNNKEL-FYRVNYIGTKNVIETCKE 134
F D+ + L K + V H A S K L +YRVN GT ++E K
Sbjct: 62 FEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKA 121
Query: 135 AGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE 190
GV+ L+ +SSA+V + +D + T + Y ++K E + +
Sbjct: 122 HGVKNLVFSSSATVYGNPQYLPLDEAHPTGGC------TNPYGKSKFFIEEMIRDLCQAD 175
Query: 191 KN--------FLTTAIRPHGIFGPRDPQ-----LVPILIEAARNGKMKF-VIGNGKNLVD 236
K F T G G DPQ L+P + + A + V GN + D
Sbjct: 176 KTWNAVLLRYFNPTGAHASGCIG-EDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTED 234
Query: 237 FTFVENVVH------GHILAAEQL 254
T V + +H GHI A +L
Sbjct: 235 GTGVRDYIHVVDLAKGHIAALRKL 258
>gi|56237023 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 45.4 bits (106), Expect = 8e-05
Identities = 70/264 (26%), Positives = 104/264 (39%), Gaps = 53/264 (20%)
Query: 37 AKRCTVIGGSGFLGQHMVEQLLARGYAVNVFD-----IQQGFDNPQ------------VR 79
A++ V GG+G++G H V +LL GY V D + G P+ V
Sbjct: 2 AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVE 61
Query: 80 FFLGDLCSRQDLYPALKGVN--TVFHCASPPP--SSNNKEL-FYRVNYIGTKNVIETCKE 134
F D+ + L K + V H A S K L +YRVN GT ++E K
Sbjct: 62 FEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKA 121
Query: 135 AGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE 190
GV+ L+ +SSA+V + +D + T + Y ++K E + +
Sbjct: 122 HGVKNLVFSSSATVYGNPQYLPLDEAHPTGGC------TNPYGKSKFFIEEMIRDLCQAD 175
Query: 191 KN--------FLTTAIRPHGIFGPRDPQ-----LVPILIEAARNGKMKF-VIGNGKNLVD 236
K F T G G DPQ L+P + + A + V GN + D
Sbjct: 176 KTWNAVLLRYFNPTGAHASGCIG-EDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTED 234
Query: 237 FTFVENVVH------GHILAAEQL 254
T V + +H GHI A +L
Sbjct: 235 GTGVRDYIHVVDLAKGHIAALRKL 258
>gi|189083684 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 45.4 bits (106), Expect = 8e-05
Identities = 70/264 (26%), Positives = 104/264 (39%), Gaps = 53/264 (20%)
Query: 37 AKRCTVIGGSGFLGQHMVEQLLARGYAVNVFD-----IQQGFDNPQ------------VR 79
A++ V GG+G++G H V +LL GY V D + G P+ V
Sbjct: 2 AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVE 61
Query: 80 FFLGDLCSRQDLYPALKGVN--TVFHCASPPP--SSNNKEL-FYRVNYIGTKNVIETCKE 134
F D+ + L K + V H A S K L +YRVN GT ++E K
Sbjct: 62 FEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKA 121
Query: 135 AGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE 190
GV+ L+ +SSA+V + +D + T + Y ++K E + +
Sbjct: 122 HGVKNLVFSSSATVYGNPQYLPLDEAHPTGGC------TNPYGKSKFFIEEMIRDLCQAD 175
Query: 191 KN--------FLTTAIRPHGIFGPRDPQ-----LVPILIEAARNGKMKF-VIGNGKNLVD 236
K F T G G DPQ L+P + + A + V GN + D
Sbjct: 176 KTWNAVLLRYFNPTGAHASGCIG-EDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTED 234
Query: 237 FTFVENVVH------GHILAAEQL 254
T V + +H GHI A +L
Sbjct: 235 GTGVRDYIHVVDLAKGHIAALRKL 258
>gi|33519455 methionine adenosyltransferase II, beta isoform 2 [Homo
sapiens]
Length = 323
Score = 38.9 bits (89), Expect = 0.008
Identities = 38/171 (22%), Positives = 78/171 (45%), Gaps = 15/171 (8%)
Query: 23 PKVNADIEKVNQN-QAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVRFF 81
P++ D+E+ N +R V G +G LG+ + ++ + + GF + +F
Sbjct: 2 PEMPEDMEQEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHA----VGCGFRRARPKFE 57
Query: 82 LGDLCSRQDLYPALKGV--NTVFHCAS---PPPSSNNKELFYRVNYIGTKNVIETCKEAG 136
+L ++ + + + HCA+ P N + ++N + N+ + + A
Sbjct: 58 QVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAK--EAAA 115
Query: 137 VQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGAN 187
V ++ S+ +F+G + ED+P P++ Y +TK+ E+AVL N
Sbjct: 116 VGAFLIYISSDYVFDGTNPPYREEDIP---APLNLYGKTKLDGEKAVLENN 163
>gi|11034825 methionine adenosyltransferase II, beta isoform 1 [Homo
sapiens]
Length = 334
Score = 36.6 bits (83), Expect = 0.037
Identities = 34/155 (21%), Positives = 70/155 (45%), Gaps = 14/155 (9%)
Query: 38 KRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKG 97
+R V G +G LG+ + ++ + + GF + +F +L ++ +
Sbjct: 29 RRVLVTGATGLLGRAVHKEFQQNNWHA----VGCGFRRARPKFEQVNLLDSNAVHHIIHD 84
Query: 98 V--NTVFHCAS---PPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFEG 152
+ + HCA+ P N + ++N + N+ + + A V ++ S+ +F+G
Sbjct: 85 FQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAK--EAAAVGAFLIYISSDYVFDG 142
Query: 153 VDIKNGTEDLPYAMKPIDYYTETKILQERAVLGAN 187
+ ED+P P++ Y +TK+ E+AVL N
Sbjct: 143 TNPPYREEDIP---APLNLYGKTKLDGEKAVLENN 174
>gi|169163903 PREDICTED: hypothetical protein [Homo sapiens]
Length = 113
Score = 32.3 bits (72), Expect = 0.71
Identities = 28/111 (25%), Positives = 43/111 (38%), Gaps = 25/111 (22%)
Query: 17 HLTEDTPK-VNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN 75
HL +D PK D+E V Q GF G H V ++ + + V F
Sbjct: 21 HLLDDQPKGEGGDVEHVQQR-----------GFAGSHFVSMVIPKAWKKEV------FSG 63
Query: 76 PQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRVNYIGTK 126
P+ F+ G + S + PA T+ +SN + R + + TK
Sbjct: 64 PRPVFWAGTVTSHGAMAPARAAAGTLL-------ASNMSLISVRSSLVNTK 107
>gi|239747712 PREDICTED: hypothetical protein XP_002348233 [Homo
sapiens]
Length = 113
Score = 32.3 bits (72), Expect = 0.71
Identities = 28/111 (25%), Positives = 43/111 (38%), Gaps = 25/111 (22%)
Query: 17 HLTEDTPK-VNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN 75
HL +D PK D+E V Q GF G H V ++ + + V F
Sbjct: 21 HLLDDQPKGEGGDVEHVQQR-----------GFAGSHFVSMVIPKAWKKEV------FSG 63
Query: 76 PQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRVNYIGTK 126
P+ F+ G + S + PA T+ +SN + R + + TK
Sbjct: 64 PRPVFWAGTVTSHGAMAPARAAAGTLL-------ASNMSLISVRSSLVNTK 107
>gi|6681764 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9,
39kDa [Homo sapiens]
Length = 377
Score = 32.3 bits (72), Expect = 0.71
Identities = 52/237 (21%), Positives = 94/237 (39%), Gaps = 42/237 (17%)
Query: 41 TVIGGSGFLGQHMVEQLLARGYAV---------NVFDIQQGFDNPQVRFFLGDLCSRQDL 91
TV G +GFLG+++V L G V ++ ++ D Q+ F D + +
Sbjct: 57 TVFGATGFLGRYVVNHLGRMGSQVIIPYRCDKYDIMHLRPMGDLGQLLFLEWDARDKDSI 116
Query: 92 YPALKGVNTVFHCASPPPSSNN---KELFYRVNYIGTKNVIETCKEAGVQKLILTSSASV 148
++ N V + + N +++F ++ + + + KEAGV+K I S +
Sbjct: 117 RRVVQHSNVVINLIGRDWETKNFDFEDVFVKI----PQAIAQLSKEAGVEKFIHVSHLN- 171
Query: 149 IFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKNFLTTAIRPHGIFGPRD 208
+IK+ + Y K + E+ V A PE ++P IFG R+
Sbjct: 172 ----ANIKSSSR-----------YLRNKAVGEKVVRDA-FPE----AIIVKPSDIFG-RE 210
Query: 209 PQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDSTLGGKAF 265
+ + R G + K + +V +V G + A +D GK+F
Sbjct: 211 DRFLNSFASMHRFGPIPLGSLGWKTVKQPVYVVDVSKGIVNAV----KDPDANGKSF 263
>gi|40068481 SET domain containing 3 isoform a [Homo sapiens]
Length = 594
Score = 31.6 bits (70), Expect = 1.2
Identities = 14/43 (32%), Positives = 20/43 (46%)
Query: 237 FTFVENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFL 279
F E + H+L + R TLG F ++ D + WTFL
Sbjct: 388 FCMTEEELKEHLLGDSAIDRIFTLGNSEFPVSWDNEVKLWTFL 430
>gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]
Length = 323
Score = 30.0 bits (66), Expect = 3.5
Identities = 15/38 (39%), Positives = 20/38 (52%)
Query: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145
P N K LF V+ T +E CK+AG+ K I S+
Sbjct: 130 PKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSN 167
>gi|239741578 PREDICTED: hypothetical protein XP_002342256 [Homo
sapiens]
Length = 113
Score = 30.0 bits (66), Expect = 3.5
Identities = 27/111 (24%), Positives = 43/111 (38%), Gaps = 25/111 (22%)
Query: 17 HLTEDTPK-VNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN 75
+L +D PK D+E V Q GF G H V ++ + + V F
Sbjct: 21 YLLDDQPKGEGGDVEHVQQR-----------GFAGSHFVSMVIPKAWKKEV------FSG 63
Query: 76 PQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRVNYIGTK 126
P+ F+ G + S + PA T+ +SN + R + + TK
Sbjct: 64 PRPVFWAGTVTSHGAMAPARAAAGTLL-------ASNMSLISVRSSLVNTK 107
>gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]
Length = 326
Score = 30.0 bits (66), Expect = 3.5
Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 3/75 (4%)
Query: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSAS-VIFEGVDIKNGTEDLPYA- 165
P N K L+++ N T +E CK+AG+ K + S+ + E + K G + P +
Sbjct: 133 PRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSN 192
Query: 166 -MKPIDYYTETKILQ 179
++ Y+T+ K+L+
Sbjct: 193 QVECHPYFTQPKLLK 207
>gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]
Length = 323
Score = 30.0 bits (66), Expect = 3.5
Identities = 15/38 (39%), Positives = 21/38 (55%)
Query: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145
P N K +F V+ T V+E CK+AG+ K I S+
Sbjct: 130 PKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSN 167
>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
Length = 1039
Score = 29.6 bits (65), Expect = 4.6
Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 7/86 (8%)
Query: 14 ARTHLTEDTP-KVNADIEKVNQNQAKRCTVIGGS-GFLGQHMVEQLLARGYAVNVFDIQQ 71
A + ED ++N +E+VN+ AK V G + ++++LA N +I
Sbjct: 651 ANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILA-----NYQEIVF 705
Query: 72 GFDNPQVRFFLGDLCSRQDLYPALKG 97
+PQ + + + C RQD A+ G
Sbjct: 706 ARTSPQQKLIIVEGCQRQDAVVAVTG 731
>gi|115430219 lambda-crystallin [Homo sapiens]
Length = 319
Score = 29.6 bits (65), Expect = 4.6
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 35 NQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQ 71
+ A C VI GSG +G+ + G+ V ++DI+Q
Sbjct: 3 SSAAGCVVIVGSGVIGRSWAMLFASGGFQVKLYDIEQ 39
>gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]
Length = 323
Score = 29.3 bits (64), Expect = 6.0
Identities = 15/38 (39%), Positives = 20/38 (52%)
Query: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145
P N K LF V+ T +E CK+AG+ K I S+
Sbjct: 130 PKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSN 167
>gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]
Length = 323
Score = 29.3 bits (64), Expect = 6.0
Identities = 15/38 (39%), Positives = 20/38 (52%)
Query: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145
P N K LF V+ T +E CK+AG+ K I S+
Sbjct: 130 PKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSN 167
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,000,212
Number of Sequences: 37866
Number of extensions: 600689
Number of successful extensions: 1233
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1178
Number of HSP's gapped (non-prelim): 37
length of query: 373
length of database: 18,247,518
effective HSP length: 104
effective length of query: 269
effective length of database: 14,309,454
effective search space: 3849243126
effective search space used: 3849243126
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.