Search of human proteins with 82546832

Search of human proteins with 82546832

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|82546832 SEC8 protein isoform b [Homo sapiens]
         (473 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|82546832 SEC8 protein isoform b [Homo sapiens]                     914   0.0  
gi|82546830 SEC8 protein isoform a [Homo sapiens]                     914   0.0  
gi|215982794 myosin VA isoform 2 [Homo sapiens]                        48   2e-05
gi|215982791 myosin VA isoform 1 [Homo sapiens]                        48   2e-05
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    44   4e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    44   4e-04
gi|71061468 centromere protein E [Homo sapiens]                        44   4e-04
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]     41   0.002
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    41   0.003
gi|149363642 coiled-coil domain containing 144A [Homo sapiens]         39   0.010
gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]           38   0.023
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       37   0.030
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       37   0.030
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        37   0.030
gi|4758650 kinesin family member 5C [Homo sapiens]                     37   0.030
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    37   0.039
gi|112420968 coiled-coil domain containing 158 [Homo sapiens]          37   0.039
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]            37   0.051
gi|34878904 synaptonemal complex protein 1 [Homo sapiens]              37   0.051
gi|224458301 family with sequence similarity 186, member A [Homo...    36   0.066
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         36   0.087
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         36   0.087
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               36   0.087
gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens]        35   0.19 
gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens]      34   0.33 
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 33   0.43 
gi|54792740 transmembrane and coiled-coil domain family 2 [Homo ...    33   0.43 
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]          33   0.56 
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]          33   0.56 
gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]          33   0.56 

>gi|82546832 SEC8 protein isoform b [Homo sapiens]
          Length = 473

 Score =  914 bits (2362), Expect = 0.0
 Identities = 473/473 (100%), Positives = 473/473 (100%)

Query: 1   MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDE 60
           MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDE
Sbjct: 1   MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDE 60

Query: 61  LIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIE 120
           LIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIE
Sbjct: 61  LIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIE 120

Query: 121 HKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLE 180
           HKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLE
Sbjct: 121 HKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLE 180

Query: 181 LHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRK 240
           LHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRK
Sbjct: 181 LHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRK 240

Query: 241 FLDTSHYSTAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAII 300
           FLDTSHYSTAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAII
Sbjct: 241 FLDTSHYSTAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAII 300

Query: 301 ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVL 360
           ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVL
Sbjct: 301 ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVL 360

Query: 361 GYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYAS 420
           GYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYAS
Sbjct: 361 GYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYAS 420

Query: 421 TGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQG 473
           TGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQG
Sbjct: 421 TGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQG 473


>gi|82546830 SEC8 protein isoform a [Homo sapiens]
          Length = 974

 Score =  914 bits (2362), Expect = 0.0
 Identities = 473/473 (100%), Positives = 473/473 (100%)

Query: 1   MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDE 60
           MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDE
Sbjct: 1   MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDE 60

Query: 61  LIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIE 120
           LIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIE
Sbjct: 61  LIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIE 120

Query: 121 HKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLE 180
           HKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLE
Sbjct: 121 HKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLE 180

Query: 181 LHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRK 240
           LHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRK
Sbjct: 181 LHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRK 240

Query: 241 FLDTSHYSTAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAII 300
           FLDTSHYSTAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAII
Sbjct: 241 FLDTSHYSTAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAII 300

Query: 301 ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVL 360
           ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVL
Sbjct: 301 ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVL 360

Query: 361 GYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYAS 420
           GYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYAS
Sbjct: 361 GYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYAS 420

Query: 421 TGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQG 473
           TGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQG
Sbjct: 421 TGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQG 473


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 69/322 (21%), Positives = 139/322 (43%), Gaps = 33/322 (10%)

Query: 40   RENEKGRLE----EAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKE 95
            RE +K ++E    E Y+K    ++  I+Q   ++    + Y+ + E++TN         E
Sbjct: 903  RELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETE 962

Query: 96   NLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASK------- 148
             L S    L    +E +      +    VL+L +EI  ++   + LEQ  + K       
Sbjct: 963  KLRSDLERLQLSEEEAK------VATGRVLSLQEEIAKLR---KDLEQTRSEKKCIEEHA 1013

Query: 149  -HYLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKM--NLHLVLIDELHRHLYIKST 205
              Y   T+ LVS ++     L Q +   + R+   +K+M   +   L++E  +     + 
Sbjct: 1014 DRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLND 1073

Query: 206  SRVVQRN--KEKGKISSLVKDASVPLIDVTNLPTP-RKFLDTSHYSTAG----SSSVREI 258
             R+  +N   E  ++     D    +  + ++P P  K  D++H S       SS + E 
Sbjct: 1074 ERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAE- 1132

Query: 259  NLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQV 318
             ++DI    E   E+   L M + +K   ++ ++ +  + + + L+++ +Q++ RS  + 
Sbjct: 1133 -MEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVL-RSKAKE 1190

Query: 319  ADSGYQRGENVTVENQPRLLLE 340
             +    RG  +  E+  R  LE
Sbjct: 1191 EERPQIRGAELEYESLKRQELE 1212



 Score = 30.4 bits (67), Expect = 3.6
 Identities = 38/189 (20%), Positives = 79/189 (41%), Gaps = 26/189 (13%)

Query: 36   DVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKE 95
            D+E   +EK  +EE  ++  ++ ++L+     E T   +  +++  RI     ++ +  E
Sbjct: 998  DLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETME 1057

Query: 96   NLLSCKMLLHCKRDELRKLWIE-GIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYL--- 151
              L          +E ++L ++   E     NLL+E   +++    L++ M    ++   
Sbjct: 1058 KKLV---------EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKP 1108

Query: 152  --SATDMLVSAVES---LEGPLLQVEGLSDLRLELHSKKMNLHLVLIDELHRHLYIKSTS 206
                TD   S+ ES       + ++E +     E   KK+ L +         L++K   
Sbjct: 1109 GHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDM--------SLFLKLQK 1160

Query: 207  RVVQRNKEK 215
            RV +  +EK
Sbjct: 1161 RVTELEQEK 1169


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 69/322 (21%), Positives = 139/322 (43%), Gaps = 33/322 (10%)

Query: 40   RENEKGRLE----EAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKE 95
            RE +K ++E    E Y+K    ++  I+Q   ++    + Y+ + E++TN         E
Sbjct: 903  RELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETE 962

Query: 96   NLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASK------- 148
             L S    L    +E +      +    VL+L +EI  ++   + LEQ  + K       
Sbjct: 963  KLRSDLERLQLSEEEAK------VATGRVLSLQEEIAKLR---KDLEQTRSEKKCIEEHA 1013

Query: 149  -HYLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKM--NLHLVLIDELHRHLYIKST 205
              Y   T+ LVS ++     L Q +   + R+   +K+M   +   L++E  +     + 
Sbjct: 1014 DRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLND 1073

Query: 206  SRVVQRN--KEKGKISSLVKDASVPLIDVTNLPTP-RKFLDTSHYSTAG----SSSVREI 258
             R+  +N   E  ++     D    +  + ++P P  K  D++H S       SS + E 
Sbjct: 1074 ERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAE- 1132

Query: 259  NLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQV 318
             ++DI    E   E+   L M + +K   ++ ++ +  + + + L+++ +Q++ RS  + 
Sbjct: 1133 -MEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVL-RSKAKE 1190

Query: 319  ADSGYQRGENVTVENQPRLLLE 340
             +    RG  +  E+  R  LE
Sbjct: 1191 EERPQIRGAELEYESLKRQELE 1212



 Score = 30.4 bits (67), Expect = 3.6
 Identities = 38/189 (20%), Positives = 79/189 (41%), Gaps = 26/189 (13%)

Query: 36   DVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKE 95
            D+E   +EK  +EE  ++  ++ ++L+     E T   +  +++  RI     ++ +  E
Sbjct: 998  DLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETME 1057

Query: 96   NLLSCKMLLHCKRDELRKLWIE-GIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYL--- 151
              L          +E ++L ++   E     NLL+E   +++    L++ M    ++   
Sbjct: 1058 KKLV---------EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKP 1108

Query: 152  --SATDMLVSAVES---LEGPLLQVEGLSDLRLELHSKKMNLHLVLIDELHRHLYIKSTS 206
                TD   S+ ES       + ++E +     E   KK+ L +         L++K   
Sbjct: 1109 GHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDM--------SLFLKLQK 1160

Query: 207  RVVQRNKEK 215
            RV +  +EK
Sbjct: 1161 RVTELEQEK 1169


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 67/296 (22%), Positives = 122/296 (41%), Gaps = 37/296 (12%)

Query: 38  EDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENL 97
           E+ ENE   LE+  E   + +  L +    E   A+    S  ER      K+K+  ++ 
Sbjct: 628 EELENELHHLEKENELLQKKITNLKIT--CEKIEALEQENSELER---ENRKLKKTLDSF 682

Query: 98  LSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQC-MASKHYLSATDM 156
            +    L     E  +L  E +E      L   +E++K    K+ Q  + +K   S  + 
Sbjct: 683 KNLTFQLESLEKENSQLDEENLE------LRRNVESLKCASMKMAQLQLENKELESEKEQ 736

Query: 157 LVSAVESLEGPLLQVEGLSDLRLELHSKKMNLHLVL------IDELHRHLY-IKSTSRVV 209
           L   +E L+    + E L      L  +   L   L      I +L   L  ++  ++ +
Sbjct: 737 LKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTL 796

Query: 210 QRNKEKGKISS-----LVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDIK 264
           Q+N E+ KISS     L K+      + + L   +K L+  +      + +++  L++  
Sbjct: 797 QKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN 856

Query: 265 EDLELDPEENSTLF--MGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQV 318
             +    +EN TL   +GI  +   +LK+           LE+E K++VKR+T  +
Sbjct: 857 VKIGNLEKENKTLSKEIGIYKESCVRLKE-----------LEKENKELVKRATIDI 901


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 67/296 (22%), Positives = 122/296 (41%), Gaps = 37/296 (12%)

Query: 38  EDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENL 97
           E+ ENE   LE+  E   + +  L +    E   A+    S  ER      K+K+  ++ 
Sbjct: 628 EELENELHHLEKENELLQKKITNLKIT--CEKIEALEQENSELER---ENRKLKKTLDSF 682

Query: 98  LSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQC-MASKHYLSATDM 156
            +    L     E  +L  E +E      L   +E++K    K+ Q  + +K   S  + 
Sbjct: 683 KNLTFQLESLEKENSQLDEENLE------LRRNVESLKCASMKMAQLQLENKELESEKEQ 736

Query: 157 LVSAVESLEGPLLQVEGLSDLRLELHSKKMNLHLVL------IDELHRHLY-IKSTSRVV 209
           L   +E L+    + E L      L  +   L   L      I +L   L  ++  ++ +
Sbjct: 737 LKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTL 796

Query: 210 QRNKEKGKISS-----LVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDIK 264
           Q+N E+ KISS     L K+      + + L   +K L+  +      + +++  L++  
Sbjct: 797 QKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN 856

Query: 265 EDLELDPEENSTLF--MGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQV 318
             +    +EN TL   +GI  +   +LK+           LE+E K++VKR+T  +
Sbjct: 857 VKIGNLEKENKTLSKEIGIYKESCVRLKE-----------LEKENKELVKRATIDI 901


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 57/292 (19%), Positives = 128/292 (43%), Gaps = 25/292 (8%)

Query: 32   STSDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYT---ELTTAIRTYQSITERITNSRN 88
            S + + +D +  +  L+   ++   ++ E++ +H     EL  A    +   E I   R 
Sbjct: 1439 SVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRV 1498

Query: 89   KIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASK 148
             + + +  + + +  L    D+L+    E  E +   N    I+ I +V +K+ +    K
Sbjct: 1499 NLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFN----IKQISEVQEKVNELKQFK 1554

Query: 149  HYLSATDMLVSAVESLEGPLLQV-----EGLSDLRLELHSKKMNLHLVLIDELHRHLYIK 203
             +  A D   SA++S+E  +L++     E   ++++ +  K+    +    ++ R    +
Sbjct: 1555 EHRKAKD---SALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKE 1611

Query: 204  STSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDI 263
            +T  +V + KE     S  K+     +   N  T  K  +  H         +++NL++I
Sbjct: 1612 NTKEIVAKMKE-----SQEKEYQFLKMTAVN-ETQEKMCEIEHLKE--QFETQKLNLENI 1663

Query: 264  K-EDLELDPEENSTL-FMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKR 313
            + E++ L    +  L  M  + K    L+ + ET+K   ++L++ L++ + R
Sbjct: 1664 ETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITR 1715



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 65/331 (19%), Positives = 148/331 (44%), Gaps = 37/331 (11%)

Query: 49   EAYEKCDR--DLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHC 106
            E    CDR  +++E + +   +L    +   ++ E ++  + KI ++ ENL   K  L  
Sbjct: 1114 ELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEI-ENL---KNELKN 1169

Query: 107  KRDELRKLWIEGIEHKHVLNL-LDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLE 165
            K   L  +  E +E    LN   +E+++I +  + L++    K + +  D L   +  +E
Sbjct: 1170 KELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQ--KSFETERDHLRGYIREIE 1227

Query: 166  GPLLQVEGLSDLRL-ELHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKD 224
               LQ +   +L++  +H K+   H   IDEL R +  K+   +  ++ EK   + L ++
Sbjct: 1228 ATGLQTK--EELKIAHIHLKE---HQETIDELRRSVSEKTAQIINTQDLEKSH-TKLQEE 1281

Query: 225  ASVPLIDVTNLPTPRKFLDTSHY-----------STAGSSSVREINLQDIKEDLELDPEE 273
              V   +   LP  ++  +T              +T  S+++  I ++ ++ + +    +
Sbjct: 1282 IPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQ 1341

Query: 274  NSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQVADSGYQRGENVTV-- 331
                     IK L K +   +T+K  +E    +LK+ ++ +  ++ +S  ++ +++ +  
Sbjct: 1342 EE-------IKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKE 1394

Query: 332  -ENQPRLLLELLELLFDKFNAVAAAHSVVLG 361
             +N+   ++  +E    K +A+      +LG
Sbjct: 1395 KDNETTKIVSEMEQFKPKDSALLRIEIEMLG 1425



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 61/292 (20%), Positives = 121/292 (41%), Gaps = 31/292 (10%)

Query: 35   DDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVK 94
            ++ E    E   L +  +K D  L  L     TEL+   +  Q  T  +    N+++Q+K
Sbjct: 838  EENERMNQEIVNLSKEAQKFDSSLGAL----KTELSYKTQELQEKTREVQERLNEMEQLK 893

Query: 95   ENLLSCKMLLHCKRDELRKLWIEGIEH--KHVLNLLDEIENIKQVPQKL--EQCMASKHY 150
            E L +    L     E + L  E ++   + V  L  E +++KQ+ + L  E+       
Sbjct: 894  EQLENRDSTLQTVERE-KTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDI 952

Query: 151  LSATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKMN-LHLVLIDELHRHLYIKSTSRVV 209
                +M +   E L   L          L+ H + +N L   + +E+ R+L+++  +   
Sbjct: 953  HDTVNMNIDTQEQLRNALES--------LKQHQETINTLKSKISEEVSRNLHMEENTGET 1004

Query: 210  QRNKEKGKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREIN-LQDI----- 263
             +++ + K+  + K   +   +   L    K  +         S ++E N LQ +     
Sbjct: 1005 -KDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVI 1063

Query: 264  --KEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKR 313
              KE L+ D +EN    + + I+   +L+ + + +K   E + QE    +K+
Sbjct: 1064 AEKEQLKTDLKEN----IEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKK 1111


>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
          Length = 1979

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 56/257 (21%), Positives = 110/257 (42%), Gaps = 24/257 (9%)

Query: 37   VEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKEN 96
            +ED+   K +L ++ ++  +++DE   QH     T  + +    E I + +  I+Q+K  
Sbjct: 919  IEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQ 978

Query: 97   LLSCKMLLHCKRDEL------RKLWIEGIEHKHVLNLLDEIENIKQVPQK-LEQCMASKH 149
            L   +  +     ++      + L IE    KH L+  +    +K + ++ LE  + ++ 
Sbjct: 979  LHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKERELEIKLLNEK 1038

Query: 150  YLSATDMLVSAVESLEGPLLQVEGLSDLRLE-LHSK-KMNLHLVLIDELHRHL--YIKST 205
             +S T  +    +   G L Q+    DL ++ LH++     H   +  L + L  Y    
Sbjct: 1039 NISLTKQIDQLSKDEVGKLTQIIQQKDLEIQALHARISSTSHTQDVVYLQQQLQAYAMER 1098

Query: 206  SRVVQRNKEKGKISSLVKDASVPLIDVT--------NLPTPRKFLDTSHYSTAGSSSVRE 257
             +V     EK + +S +K     ++D+          L    K L T  + ++G    RE
Sbjct: 1099 EKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENKKLST-RFESSGQDMFRE 1157

Query: 258  I--NLQDI--KEDLELD 270
               NL  I  ++D+E+D
Sbjct: 1158 TIQNLSRIIREKDIEID 1174


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 56/262 (21%), Positives = 112/262 (42%), Gaps = 36/262 (13%)

Query: 41   ENEKGRLEEAYEKCD---RDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENL 97
            + EK +L++  ++ +   +D  +  + +  E+    R  + + +++TN  NKI+ +++ +
Sbjct: 1132 QKEKKQLQKTMQELELVKKDAQQTTLMNM-EIADYERLMKELNQKLTNKNNKIEDLEQEI 1190

Query: 98   LSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDML 157
               K      ++E+  L         V    ++   IKQ+  K ++ +A         ++
Sbjct: 1191 KIQKQKQETLQEEITSL------QSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLI 1244

Query: 158  VSAVESLEGPL----LQVE----GLSDLRLELHSKKMNLHLVLIDELHRHLYIKSTSRVV 209
            + A  SL+G L     QVE     L+++  E H  K++ HL    E H+        RV 
Sbjct: 1245 LQA--SLKGELEASQQQVEVYKIQLAEITSEKH--KIHEHLKTSAEQHQRTLSAYQQRVT 1300

Query: 210  QRNKE----KGKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVRE-------- 257
               +E    K + +++  +     + V N+   +K    S   T G+   RE        
Sbjct: 1301 ALQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQ 1360

Query: 258  --INLQDIKEDLELDPEENSTL 277
              I LQD + +L+++  E  TL
Sbjct: 1361 LKIKLQDSQNNLQINVSELQTL 1382


>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
          Length = 1427

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 65/307 (21%), Positives = 135/307 (43%), Gaps = 36/307 (11%)

Query: 79   ITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVP 138
            ++E+++N+ +KI        S ++ LH  RD L +   E +  + V   L + +  K+  
Sbjct: 968  LSEKLSNAESKIN-------SLQIQLHNTRDALGR---ESLILERVQRDLSQTQCQKKET 1017

Query: 139  QKLEQCMASK--HYLSATDMLVSAVESLEGP-LLQVEGLSDLRLELHSKKMNLHLVLIDE 195
            +++ Q   SK   Y++  + +   +  L+   +L  + L D   + +S++     +  D+
Sbjct: 1018 EQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQ-DQ 1076

Query: 196  LHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSV 255
             H      S ++ +Q   EK  +S  +++ +  L+D  N    R  +D      AG    
Sbjct: 1077 FH------SAAKNLQAESEKQILS--LQEKNKELMDEYNHLKER--MDQCEKEKAG---- 1122

Query: 256  REINLQDIKED-----LELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQI 310
            R+I+L + +E      L LD E N  L +   +  +  ++K  ET++   ++L+QE+  +
Sbjct: 1123 RKIDLTEAQETVPSRCLHLDAE-NEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNL 1181

Query: 311  VKRSTTQVADSGYQRGENVTVENQPRLLLE--LLELLFDKFNAVAAAHSVVLGYLQDTVV 368
                   + + G      + +E + R  +E  L E +       A +H  ++   +D   
Sbjct: 1182 KSYMERNMLERGKAEWHKLLIEERARKEIEEKLNEAILTLQKQAAVSHEQLVQLREDNTT 1241

Query: 369  TPLTQQE 375
            +  TQ E
Sbjct: 1242 SIKTQME 1248


>gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]
          Length = 1194

 Score = 37.7 bits (86), Expect = 0.023
 Identities = 34/149 (22%), Positives = 68/149 (45%), Gaps = 8/149 (5%)

Query: 4   EAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDELIV 63
           E A  + R+ V + ++   +L   +  L   +++     E G+ EEA  K  RDL E + 
Sbjct: 239 EEALERQRAEVCQLRERLAVLCRQMSQLE--EELGTAHRELGKAEEANSKLQRDLKEALA 296

Query: 64  QH---YTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKL--WIEG 118
           Q       +TT  + Y S     T+  +   +++  L S + L     ++ R+L  W++ 
Sbjct: 297 QREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDD 356

Query: 119 IEHKHVLNLLDEIENIKQVPQKLEQCMAS 147
            + K +   L + E + ++  +L Q +A+
Sbjct: 357 AKQK-LQQTLQKAETLPEIEAQLAQRVAA 384


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 37.4 bits (85), Expect = 0.030
 Identities = 71/379 (18%), Positives = 158/379 (41%), Gaps = 58/379 (15%)

Query: 14  VSKSKDPSGLLISVIRTLSTSDDVEDR-----ENEKGRL--EEAYEKCDRDLDEL----- 61
           V+K  +   L   +  TL +   +E R     E+E+ R+  EE+ +   +D+ E      
Sbjct: 523 VAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALK 582

Query: 62  --IVQHYTEL---TTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWI 116
             I Q ++++   T+A    + + + I     +IKQ +++L S +  L  K +EL+ +  
Sbjct: 583 AQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQN 642

Query: 117 EGIEHKHVLNLLDEIENIK-QVPQKLEQCMASKHYLSATDMLV--SAVESLEGPLLQVEG 173
                K  +  L  + N +     +LE+   S +       L+       +   + + + 
Sbjct: 643 MNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKI 702

Query: 174 LSDLRLELHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVT 233
           L+D    L S+   L  ++ ++ ++ + ++   + +Q   EK                  
Sbjct: 703 LNDQNKALKSEVQKLQTLVSEQPNKDV-VEQMEKCIQEKDEK------------------ 743

Query: 234 NLPTPRKFLDTSHYSTAGS----SSVREINLQDIKEDLELDPEENSTLFMGILIKGL--- 286
            L T  + L+T     A      +++R  N    KE  +L  ++N  +    L++ L   
Sbjct: 744 -LKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKV 802

Query: 287 -----AKLKKIPETVKAII------ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQP 335
                 K+K + E ++A +      E+  Q+LKQ +K    ++ +   ++ + +++ ++ 
Sbjct: 803 IHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKV 862

Query: 336 RLLLELLELLFDKFNAVAA 354
           + L  LL+   ++ N + A
Sbjct: 863 QELQNLLKGKEEQMNTMKA 881


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 37.4 bits (85), Expect = 0.030
 Identities = 71/379 (18%), Positives = 158/379 (41%), Gaps = 58/379 (15%)

Query: 14  VSKSKDPSGLLISVIRTLSTSDDVEDR-----ENEKGRL--EEAYEKCDRDLDEL----- 61
           V+K  +   L   +  TL +   +E R     E+E+ R+  EE+ +   +D+ E      
Sbjct: 523 VAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALK 582

Query: 62  --IVQHYTEL---TTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWI 116
             I Q ++++   T+A    + + + I     +IKQ +++L S +  L  K +EL+ +  
Sbjct: 583 AQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQN 642

Query: 117 EGIEHKHVLNLLDEIENIK-QVPQKLEQCMASKHYLSATDMLV--SAVESLEGPLLQVEG 173
                K  +  L  + N +     +LE+   S +       L+       +   + + + 
Sbjct: 643 MNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKI 702

Query: 174 LSDLRLELHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVT 233
           L+D    L S+   L  ++ ++ ++ + ++   + +Q   EK                  
Sbjct: 703 LNDQNKALKSEVQKLQTLVSEQPNKDV-VEQMEKCIQEKDEK------------------ 743

Query: 234 NLPTPRKFLDTSHYSTAGS----SSVREINLQDIKEDLELDPEENSTLFMGILIKGL--- 286
            L T  + L+T     A      +++R  N    KE  +L  ++N  +    L++ L   
Sbjct: 744 -LKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKV 802

Query: 287 -----AKLKKIPETVKAII------ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQP 335
                 K+K + E ++A +      E+  Q+LKQ +K    ++ +   ++ + +++ ++ 
Sbjct: 803 IHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKV 862

Query: 336 RLLLELLELLFDKFNAVAA 354
           + L  LL+   ++ N + A
Sbjct: 863 QELQNLLKGKEEQMNTMKA 881


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 37.4 bits (85), Expect = 0.030
 Identities = 71/379 (18%), Positives = 158/379 (41%), Gaps = 58/379 (15%)

Query: 14  VSKSKDPSGLLISVIRTLSTSDDVEDR-----ENEKGRL--EEAYEKCDRDLDEL----- 61
           V+K  +   L   +  TL +   +E R     E+E+ R+  EE+ +   +D+ E      
Sbjct: 523 VAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALK 582

Query: 62  --IVQHYTEL---TTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWI 116
             I Q ++++   T+A    + + + I     +IKQ +++L S +  L  K +EL+ +  
Sbjct: 583 AQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQN 642

Query: 117 EGIEHKHVLNLLDEIENIK-QVPQKLEQCMASKHYLSATDMLV--SAVESLEGPLLQVEG 173
                K  +  L  + N +     +LE+   S +       L+       +   + + + 
Sbjct: 643 MNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKI 702

Query: 174 LSDLRLELHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVT 233
           L+D    L S+   L  ++ ++ ++ + ++   + +Q   EK                  
Sbjct: 703 LNDQNKALKSEVQKLQTLVSEQPNKDV-VEQMEKCIQEKDEK------------------ 743

Query: 234 NLPTPRKFLDTSHYSTAGS----SSVREINLQDIKEDLELDPEENSTLFMGILIKGL--- 286
            L T  + L+T     A      +++R  N    KE  +L  ++N  +    L++ L   
Sbjct: 744 -LKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKV 802

Query: 287 -----AKLKKIPETVKAII------ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQP 335
                 K+K + E ++A +      E+  Q+LKQ +K    ++ +   ++ + +++ ++ 
Sbjct: 803 IHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKV 862

Query: 336 RLLLELLELLFDKFNAVAA 354
           + L  LL+   ++ N + A
Sbjct: 863 QELQNLLKGKEEQMNTMKA 881


>gi|4758650 kinesin family member 5C [Homo sapiens]
          Length = 957

 Score = 37.4 bits (85), Expect = 0.030
 Identities = 55/256 (21%), Positives = 105/256 (41%), Gaps = 24/256 (9%)

Query: 68  ELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHK-HVLN 126
           E T A      +   + +  N+ KQ++   +     ++    EL    +   +H+  + +
Sbjct: 583 EFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKS 642

Query: 127 LLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKM 186
           L D ++N++Q  ++LE+   S+  LS     + A E +     Q +    L     +++M
Sbjct: 643 LTDYMQNMEQKRRQLEE---SQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEM 699

Query: 187 NLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPL-IDVTNLPTPRKFLDTS 245
              L    E HR  + K  SR+    +EK KI   ++D +  L ++   L          
Sbjct: 700 KKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKL---------- 749

Query: 246 HYSTAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQ 305
                 SS   ++ ++D + +++L   E   L      +    LK + ETV   ++ L  
Sbjct: 750 ------SSDYNKLKIEDQEREMKL---EKLLLLNDKREQAREDLKGLEETVSRELQTLHN 800

Query: 306 ELKQIVKRSTTQVADS 321
             K  V+  TT+V  S
Sbjct: 801 LRKLFVQDLTTRVKKS 816


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 37.0 bits (84), Expect = 0.039
 Identities = 67/311 (21%), Positives = 126/311 (40%), Gaps = 44/311 (14%)

Query: 25   ISVIRTLST--SDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITER 82
            + V+R L    ++  ED E+EK    +A EK  RDL E +    TEL   + T  +  E 
Sbjct: 1110 LKVVRELQAQIAELQEDFESEKASRNKA-EKQKRDLSEELEALKTELEDTLDTTAAQQEL 1168

Query: 83   ITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLE 142
             T    ++ ++K+ L         K  E +   I+ +  +H   L +  E ++Q  +   
Sbjct: 1169 RTKREQEVAELKKALEE-----ETKNHEAQ---IQDMRQRHATALEELSEQLEQAKRFKA 1220

Query: 143  QCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKMNLHLVLIDELHR---- 198
                +K  L   +  ++          +V+ L  ++ E   K+  L    + ELH     
Sbjct: 1221 NLEKNKQGLETDNKELAC---------EVKVLQQVKAESEHKRKKLD-AQVQELHAKVSE 1270

Query: 199  --HLYIKSTSRVVQRNKEKGKISSLVKDASVPLI----DVTNL-----PTPRKFLDTSHY 247
               L ++   +  +   E   +S+L+++A    I    D  +L      T     + +  
Sbjct: 1271 GDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQ 1330

Query: 248  STAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAI------IE 301
                SS +R+  L++ K  L+   EE       +  + LA   ++ +T K +      IE
Sbjct: 1331 KLNLSSRIRQ--LEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIE 1388

Query: 302  RLEQELKQIVK 312
             LE+  K+++K
Sbjct: 1389 SLEEAKKKLLK 1399


>gi|112420968 coiled-coil domain containing 158 [Homo sapiens]
          Length = 1113

 Score = 37.0 bits (84), Expect = 0.039
 Identities = 79/439 (17%), Positives = 180/439 (41%), Gaps = 44/439 (10%)

Query: 37  VEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKEN 96
           V    +E    +  YE    +L++ +V   +ELT A       ++   N  ++++++  +
Sbjct: 326 VSQLRSELREAKRMYEDKTEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLAD 385

Query: 97  LLSCKMLLHCKRDELRKLWIEGIEHKHVL-NLLDEIENIKQVPQKLEQCMASKHYLSATD 155
           L   +  L  ++++ ++LW     +   + +L  E++N     Q+LE  + +        
Sbjct: 386 LHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDNRNMEVQRLEALLKALK-SECQG 444

Query: 156 MLVSAVESLEGPLLQVEGLSDLRLELHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEK 215
            +   + +++G    +E +S L  +L S K  L  V+ +   + + ++S+ R        
Sbjct: 445 QMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERT------- 497

Query: 216 GKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDIKE-DLELDPEEN 274
             IS L           T+L    + ++ ++       S  ++ LQ+++    E D   N
Sbjct: 498 --ISDL----------TTSLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRN 545

Query: 275 STLFMGILIKGLAKLKKIPETVK-AIIERLEQELKQIVKRSTTQVADSGYQRGENVTVE- 332
                   ++   +  K+  T K  +IE L Q+++ + +        +G  + E   +E 
Sbjct: 546 --------VQTECEALKLQMTEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEK 597

Query: 333 --NQPRLLLELLELLFDKFNAVAAAHSVVLGYLQDTVVTPLTQQEDIKLYDMADVWVKIQ 390
             N  R+ L+ L++L DK +A        +  L+   V  L      +L  + D+  +  
Sbjct: 598 EINDRRMELKELKILKDKKDAKIRELEARVSDLELEKV-KLVNAGSERLRAVKDIKQERD 656

Query: 391 DVLQMLLTEYLDMKN--------TRTASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLF 442
            +L  + T   ++ N         R     S ++   +   +     A+ + ++ +N+L 
Sbjct: 657 QLLNEVKTSRSELNNLSEEYEVLKRNFRNKSEEMEMTTNKLKMQLKSAQSELEQTRNTLK 716

Query: 443 KFE-SSSHAISMSAYLREQ 460
             E S  HA+ ++  +++Q
Sbjct: 717 SMEGSDGHAMKVAMGMQKQ 735


>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
          Length = 4024

 Score = 36.6 bits (83), Expect = 0.051
 Identities = 37/175 (21%), Positives = 82/175 (46%), Gaps = 11/175 (6%)

Query: 28   IRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSR 87
            +  + +S D+  +  E+GR   A +K  RD+   ++Q    LT  + T   + ER+  S 
Sbjct: 990  LEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLT--VVTIDRMLERLKKSN 1047

Query: 88   NKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMAS 147
              ++ + + L      L  KR    + +   + +  +L +L E ++  +V   L++C   
Sbjct: 1048 ELLELILKGL---NEYLEKKRLFFPRFFF--LSNDELLEILSETKDPTRVQPHLKKCFEG 1102

Query: 148  KHYLSATDML-VSAVESLEG---PLLQVEGLSDLRLELHSKKMNLHLVLIDELHR 198
               +  T+ L ++ ++S EG    L+++   +  R ++    + L  V+I+ +H+
Sbjct: 1103 IAKVEFTETLDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHK 1157


>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
          Length = 976

 Score = 36.6 bits (83), Expect = 0.051
 Identities = 65/323 (20%), Positives = 135/323 (41%), Gaps = 33/323 (10%)

Query: 17  SKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTY 76
           +K+   + +S+ R++ST             LEE  +   + + +L  +  T++  + +  
Sbjct: 321 TKELEDIKVSLQRSVSTQK----------ALEEDLQIATKTICQLTEEKETQMEESNKAR 370

Query: 77  QSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQ 136
            + +  +T     +  ++E L + +  L    D+L+ L +E  +    L  + ++ N K+
Sbjct: 371 AAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKE 430

Query: 137 VP-QKLEQCMASKHYLSATDMLVSAV-ESLEGPLLQVEGLSDLR-LELHSKKMNLHLVLI 193
           V  ++L++ +  K  L   +     + E L+G   ++ GL   R  E+H  ++ L  +  
Sbjct: 431 VELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITT 490

Query: 194 DELHRHLYIKSTSRVVQRNKEKG--------KISSLVKDASVPLIDVTNLPTPRKFLDTS 245
            E +    +K     ++  K K         K+S   K+ +    D+T L    +  D +
Sbjct: 491 SEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMT-LELKNQQEDIN 549

Query: 246 HYSTAGSSSVREI-NLQD----IKEDLELDPEENSTLFMGILIK------GLAKLKKIPE 294
           +        +++I NLQ+    ++ +LE   EE       +  K          L+K  E
Sbjct: 550 NNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVE 609

Query: 295 TVKAIIERLEQELKQIVKRSTTQ 317
                IE L+QE K + K+ T +
Sbjct: 610 NKNKYIEELQQENKALKKKGTAE 632



 Score = 29.3 bits (64), Expect = 8.1
 Identities = 60/342 (17%), Positives = 143/342 (41%), Gaps = 57/342 (16%)

Query: 47  LEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHC 106
           LE+ Y+K   D ++ +     ++T      + +T  +  SR+K+ Q++E           
Sbjct: 253 LEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEK-------TKL 305

Query: 107 KRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEG 166
           + + L+    + IE +H  +L  E+E+IK         ++ +  +S    L   ++    
Sbjct: 306 QSENLK----QSIEKQH--HLTKELEDIK---------VSLQRSVSTQKALEEDLQIATK 350

Query: 167 PLLQVEGLSDLRLELHSKKMNLHLVLIDELHRHL-----YIKSTSRVVQRNKEKGKISSL 221
            + Q+    + ++E  +K    H  ++ E    +      +++  + +++N+++ KI ++
Sbjct: 351 TICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTM 410

Query: 222 -VKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDIKEDLELDPEENSTLFMG 280
            ++  S  L ++T L                 ++ +E+ L+++K+ L    E+ + L+  
Sbjct: 411 ELQKKSSELEEMTKL-----------------TNNKEVELEELKKVL---GEKETLLYEN 450

Query: 281 ILIKGLA-KLKKIPETVKAIIERLEQELKQIVKRSTTQVADSGYQRGE----NVTVENQP 335
              + +A +LK   + +  +++  E+E+  +  + T       Y   E       +EN+ 
Sbjct: 451 KQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEK 510

Query: 336 RLLLELLELLFDKFNAVAAAHSVVLGYLQDTVVTPLTQQEDI 377
               EL        N ++  +  +     D  +    QQEDI
Sbjct: 511 LKNTELT----SHCNKLSLENKELTQETSDMTLELKNQQEDI 548


>gi|224458301 family with sequence similarity 186, member A [Homo
           sapiens]
          Length = 2351

 Score = 36.2 bits (82), Expect = 0.066
 Identities = 46/216 (21%), Positives = 89/216 (41%), Gaps = 19/216 (8%)

Query: 215 KGKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDIKEDLELDPEEN 274
           KG+I SLV+  S+   D T  P   K     H+ ++G+ + +E   ++ KE+L    + +
Sbjct: 579 KGEIRSLVEPLSMIQFDDTAEPQKGKIKGKKHHISSGTITSKEEKTEE-KEELTKQVKSH 637

Query: 275 STLFMGILIKGLAKLKKIPETVKAIIERLE--------QELKQIVKRSTTQVADSGYQRG 326
                  L+K L+++ K       ++E  +        +E ++ +     Q  D+  +  
Sbjct: 638 Q------LVKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAF 691

Query: 327 ENVTVENQPRLLLELLELLFDKFNAVAAAHSVVLGYLQDTVVTPLTQQEDIKLYD-MADV 385
           +  TV  +  LL        +K   + A        + +TV   L + +D K  + + + 
Sbjct: 692 DKKTVPKEEELLKRAEA---EKLGIIKAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEK 748

Query: 386 WVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYAST 421
            +K + V+  +   +         SE S  LSY ST
Sbjct: 749 PIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYEST 784


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 35.8 bits (81), Expect = 0.087
 Identities = 70/384 (18%), Positives = 157/384 (40%), Gaps = 39/384 (10%)

Query: 37  VEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKEN 96
           +E  E+E    +   E+ +R+L+E+ V + TE    ++  Q     I      I Q+  N
Sbjct: 157 LEMMESELAGKQHEIEELNRELEEMRVTYGTE---GLQQLQEFEAAIKQRDGIITQLTAN 213

Query: 97  LLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDM 156
           L   +     ++DE  + ++E  E    L +       +Q+ Q  E    S H  +A D+
Sbjct: 214 LQQARR----EKDETMREFLELTEQSQKLQI-----QFQQL-QASETLRNSTHSSTAADL 263

Query: 157 LVSAVESLEGPLLQVEGLSDLRLELHSKK--MNLHLVLIDELHRHLYIKSTSRVVQRNKE 214
           L  A + +     Q+E    L  +   KK    + +  + E  +   ++   +V   NKE
Sbjct: 264 L-QAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKE 322

Query: 215 KGKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDIKEDLEL----- 269
           + +     K+  +  ++   +   +K L+     T     + E+  Q ++++ E+     
Sbjct: 323 EIQ----EKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKL 378

Query: 270 ----------DPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQVA 319
                        E     MG + +   +  K  +    I++R+EQE ++ +++   ++ 
Sbjct: 379 ELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELD 438

Query: 320 DSGYQRGENVTVENQPRLLLELLELLF----DKFNAVAAAHSVVLGYLQDTVVTPLTQQE 375
           +   Q+   +  E   + + ++ E+      +  NA+ +  ++ +   Q  ++     + 
Sbjct: 439 EMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINEL 498

Query: 376 DIKLYDMADVWVKIQDVLQMLLTE 399
           +IKL D      K+++ L ++L E
Sbjct: 499 NIKLQDTNSQKEKLKEELGLILEE 522


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 35.8 bits (81), Expect = 0.087
 Identities = 70/384 (18%), Positives = 157/384 (40%), Gaps = 39/384 (10%)

Query: 37  VEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKEN 96
           +E  E+E    +   E+ +R+L+E+ V + TE    ++  Q     I      I Q+  N
Sbjct: 157 LEMMESELAGKQHEIEELNRELEEMRVTYGTE---GLQQLQEFEAAIKQRDGIITQLTAN 213

Query: 97  LLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDM 156
           L   +     ++DE  + ++E  E    L +       +Q+ Q  E    S H  +A D+
Sbjct: 214 LQQARR----EKDETMREFLELTEQSQKLQI-----QFQQL-QASETLRNSTHSSTAADL 263

Query: 157 LVSAVESLEGPLLQVEGLSDLRLELHSKK--MNLHLVLIDELHRHLYIKSTSRVVQRNKE 214
           L  A + +     Q+E    L  +   KK    + +  + E  +   ++   +V   NKE
Sbjct: 264 L-QAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKE 322

Query: 215 KGKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDIKEDLEL----- 269
           + +     K+  +  ++   +   +K L+     T     + E+  Q ++++ E+     
Sbjct: 323 EIQ----EKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKL 378

Query: 270 ----------DPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQVA 319
                        E     MG + +   +  K  +    I++R+EQE ++ +++   ++ 
Sbjct: 379 ELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELD 438

Query: 320 DSGYQRGENVTVENQPRLLLELLELLF----DKFNAVAAAHSVVLGYLQDTVVTPLTQQE 375
           +   Q+   +  E   + + ++ E+      +  NA+ +  ++ +   Q  ++     + 
Sbjct: 439 EMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINEL 498

Query: 376 DIKLYDMADVWVKIQDVLQMLLTE 399
           +IKL D      K+++ L ++L E
Sbjct: 499 NIKLQDTNSQKEKLKEELGLILEE 522


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 35.8 bits (81), Expect = 0.087
 Identities = 84/399 (21%), Positives = 167/399 (41%), Gaps = 39/399 (9%)

Query: 41   ENEKG---RLEEAYEKCDRDLDELIVQHYTELTTAI---RTYQSITERITNSRNKIKQVK 94
            ENEKG   +L++  ++    + +L  +   E TT     R    +T+ + +   ++++V 
Sbjct: 1107 ENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVG 1166

Query: 95   ENLLSCKMLLHCKRDELRKLWIE-------------GIEHKHVLNLLD---EIENIKQVP 138
             + L+   +   +  + +KL  +              ++ +H  +L +   ++EN++QV 
Sbjct: 1167 GSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVK 1226

Query: 139  QKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDL---RLELHSKKMNLHLVLIDE 195
            QKLE+  +        D L++ VE +       E L  L   RL   + K++    L ++
Sbjct: 1227 QKLEKDKSDLQL--EVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLAND 1284

Query: 196  L---HRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNL--PTPRKFLDTSHYSTA 250
            L      L+ +S   + +  +++  I+ L ++ S     + +L     ++    S  + A
Sbjct: 1285 LAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHA 1344

Query: 251  GSSSVREINL--QDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELK 308
               + R+ +L  +  +E+ E+  E + TL   +  + +    K    V    E LE   K
Sbjct: 1345 LQKAQRDCDLLREQYEEEQEVKAELHRTL-SKVNAEMVQWRMKYENNVIQRTEDLEDAKK 1403

Query: 309  QIVKRSTTQVADSGYQRGENVTVEN-QPRLLLELLELLFDKFNAVAAAHSVVLGYLQDTV 367
            ++  R        G     N ++E  + +L LEL + L D     +AA  +    LQ   
Sbjct: 1404 ELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGK 1463

Query: 368  VTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNT 406
                 +Q+  +   + D     Q  +Q L TE L +KNT
Sbjct: 1464 ALADWKQKHEESQALLDA---SQKEVQALSTELLKLKNT 1499



 Score = 29.3 bits (64), Expect = 8.1
 Identities = 47/241 (19%), Positives = 98/241 (40%), Gaps = 23/241 (9%)

Query: 33   TSDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQ 92
            T DD+   E +   L +A  K ++ +DEL      E    +   + +  ++  +    ++
Sbjct: 1018 TLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCEREL-HKLEGNLKLNRE 1076

Query: 93   VKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLS 152
              ENL S +  L    +ELRK  +E      +  +  ++EN K +  +L++ +       
Sbjct: 1077 SMENLESSQRHL---AEELRKKELE------LSQMNSKVENEKGLVAQLQKTVKE----- 1122

Query: 153  ATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKMNLHLVLIDELHRHLYIKSTSRVVQRN 212
                L + ++ L+   L+ E  +  ++E     +   L  ++E    +   S +++    
Sbjct: 1123 ----LQTQIKDLK-EKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITK 1177

Query: 213  KEKGKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDIKEDLELDPE 272
            K++ K   L +D     +   +  T    L   H  +      +  NLQ +K+ LE D  
Sbjct: 1178 KQETKFQKLHRDMEEATL---HFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKS 1234

Query: 273  E 273
            +
Sbjct: 1235 D 1235


>gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens]
          Length = 388

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 63/300 (21%), Positives = 122/300 (40%), Gaps = 42/300 (14%)

Query: 61  LIVQHYTELTTAIRTYQSITERITNSRNKIKQVK------ENLLSC-KMLLHCKRDELRK 113
           L+ +    L T  + Y+++ E +T    + + +K      EN L   K LL+  R+E+  
Sbjct: 2   LLKEKEDSLMTCQQIYKALQEELTVKEKQEEDIKRRINLAENELEITKTLLNQTREEVLT 61

Query: 114 LWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEG 173
           L     +++  L L+   ++I+Q+ + L Q + S              E +E  L +   
Sbjct: 62  L-----KNERELMLISHQKSIEQLQETLRQKLLSDDNWK---------EKIEAELAKERA 107

Query: 174 LSDLRLE----LHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPL 229
              +  E    L  ++  L L +  E H+ +  K      ++ + + KIS L+  A+  L
Sbjct: 108 QHLVEFEEQALLFKEETKLQLDIEKEKHQDVIQKYKK---EQEELQMKISDLITGATRDL 164

Query: 230 IDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKL 289
                + T ++ L  SH      S+ +E  ++++K  +          F   L K +   
Sbjct: 165 RQ--EVTTLKEKLHKSHTRYTEESNSKEKEIENLKNLV--------AEFESRLKKEIDSN 214

Query: 290 KKIPETVKAIIERLEQELKQIVKRSTTQVADSGYQRGENV----TVENQPRLLLELLELL 345
             + E ++  +E+   ELK+++   T  +      + EN     TV  +     EL E L
Sbjct: 215 DSVSENLRKEMEQKSDELKRVMLAQTQLIEQFNQSQEENTFLQETVRRECEERFELTEAL 274


>gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens]
          Length = 757

 Score = 33.9 bits (76), Expect = 0.33
 Identities = 53/239 (22%), Positives = 105/239 (43%), Gaps = 41/239 (17%)

Query: 36  DVEDRENEKGRLEEAYEKCDRDLDELIVQ-----HYTELTTAIRTYQSITERITNSRNKI 90
           +++ + +E     + YEK +++LDE+I+Q     +  E    + +Y       T ++ ++
Sbjct: 515 ELQAQNSEHQARLDIYEKLEKELDEIIMQTAEIENEDEAERVLFSYGYGANVPTTAKRRL 574

Query: 91  KQ-----------VKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDE-----IENI 134
           KQ            K+N L  K L H ++D++ +L  E      +LN   +     IE++
Sbjct: 575 KQSVHLARRVLQLEKQNSLILKDLEH-RKDQVTQLSQELDRANSLLNQTQQPYRYLIESV 633

Query: 135 KQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLEL---HSKKMNLHLV 191
           +Q   K++    S   ++  +  VS +   +  LLQ +    L LE    H +++     
Sbjct: 634 RQRDSKIDSLTES---IAQLEKDVSNLNKEKSALLQTKNQMALDLEQLLNHREELAAMKQ 690

Query: 192 LIDELH-RH-----LYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRKFLDT 244
           ++ ++H +H     L  K+  + V  N++        K  +VP     N+ TP+  L T
Sbjct: 691 ILVKMHSKHSENSLLLTKTEPKHVTENQKS-------KTLNVPKEHEDNIFTPKPTLFT 742


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 33.5 bits (75), Expect = 0.43
 Identities = 81/376 (21%), Positives = 159/376 (42%), Gaps = 66/376 (17%)

Query: 29   RTLSTSDDVEDRENEKGRLEEAYEKCDRDLDEL------IVQHYTELTTAIR------TY 76
            R  S +D++ D  NE  + ++AY K  R+ +E+      + +    LT+ ++        
Sbjct: 1811 RENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKPLTDNK 1870

Query: 77   QSITERITNSRNKIK-----QVKENLLSCKMLLHCKRDELR----KLW---IEGIEHK-- 122
            QS+ E +     K++     +V+E  L      + K + +R    K W   IEGI +K  
Sbjct: 1871 QSLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLK 1930

Query: 123  ----HVLNLLDEIENIKQVPQKLE-QCMASKHYLSATDMLVS---AVESLEGPLLQVEGL 174
                 V  L  ++  +K +  K + + +  +  L  T M V     + +LE    ++E L
Sbjct: 1931 EKEGEVFTLTKQLNTLKDLFAKADKEKLTLQRKLKTTGMTVDQVLGIRALESE-KELEEL 1989

Query: 175  SDLRLELHSK--KMNLHLVL-----IDELH---RHLYIKSTSRVVQRNKE---KGKISSL 221
                L+L +    M  H  L     +++LH   R+L  K  +   Q +K+   K  IS +
Sbjct: 1990 KKRNLDLENDILYMRAHQALPRDSVVEDLHLQNRYLQEKLHALEKQFSKDTYSKPSISGI 2049

Query: 222  VKDASVPL---IDVTNLPTPRKFLDTSHYSTAGSSSVREI--NLQDIKEDLELDPEENST 276
              D        +   NL    + ++        +  +  +   ++D+KE  E   +E + 
Sbjct: 2050 ESDDHCQREQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKEKAE 2109

Query: 277  L--------FMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQVADSGYQRGEN 328
            +          G   K + +L+K    +K ++E++++E +Q+ K S    +    ++  N
Sbjct: 2110 VQRKLGHVRGSGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTS----EKMAN 2165

Query: 329  VTVENQPRLLLELLEL 344
            +  EN+ +L  EL +L
Sbjct: 2166 IEQENE-KLKAELEKL 2180


>gi|54792740 transmembrane and coiled-coil domain family 2 [Homo
           sapiens]
          Length = 709

 Score = 33.5 bits (75), Expect = 0.43
 Identities = 20/88 (22%), Positives = 45/88 (51%), Gaps = 4/88 (4%)

Query: 51  YEKCDRDLDELIVQHYTELTTAIRTYQSITERIT-NSRNKIKQVKENLLSC---KMLLHC 106
           YE+ +  L++L   H  E+T   +   S+ E++   S  + + ++E + SC      L  
Sbjct: 562 YERLEEQLNDLTELHQNEMTNLKQELASMEEKVAYQSYERARDIQEAVESCLTRVTKLEL 621

Query: 107 KRDELRKLWIEGIEHKHVLNLLDEIENI 134
           ++ + + + +EG+E+ +   LL +  N+
Sbjct: 622 QQQQQQVVQLEGVENANARALLGKFINV 649


>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
          Length = 445

 Score = 33.1 bits (74), Expect = 0.56
 Identities = 36/155 (23%), Positives = 67/155 (43%), Gaps = 34/155 (21%)

Query: 35  DDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAI-----RTYQSITERITNSRNK 89
           ++ + R  E  RL E  EK    L   +++H TE++  +       YQ + E   + R +
Sbjct: 293 EEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRER 352

Query: 90  IKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKH 149
           I+ + +       ++HC             + K V  +++EIE++K   +KL+Q    K 
Sbjct: 353 IRHLDD-------MVHC-------------QQKKVKQMVEEIESLK---KKLQQ----KQ 385

Query: 150 YLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSK 184
            L     L+  +  LEG   +++   D   E  +K
Sbjct: 386 LLIL--QLLEKISFLEGENNELQSRLDYLTETQAK 418


>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
          Length = 550

 Score = 33.1 bits (74), Expect = 0.56
 Identities = 36/155 (23%), Positives = 67/155 (43%), Gaps = 34/155 (21%)

Query: 35  DDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAI-----RTYQSITERITNSRNK 89
           ++ + R  E  RL E  EK    L   +++H TE++  +       YQ + E   + R +
Sbjct: 293 EEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRER 352

Query: 90  IKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKH 149
           I+ + +       ++HC             + K V  +++EIE++K   +KL+Q    K 
Sbjct: 353 IRHLDD-------MVHC-------------QQKKVKQMVEEIESLK---KKLQQ----KQ 385

Query: 150 YLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSK 184
            L     L+  +  LEG   +++   D   E  +K
Sbjct: 386 LLIL--QLLEKISFLEGENNELQSRLDYLTETQAK 418


>gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]
          Length = 466

 Score = 33.1 bits (74), Expect = 0.56
 Identities = 36/155 (23%), Positives = 67/155 (43%), Gaps = 34/155 (21%)

Query: 35  DDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAI-----RTYQSITERITNSRNK 89
           ++ + R  E  RL E  EK    L   +++H TE++  +       YQ + E   + R +
Sbjct: 293 EEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRER 352

Query: 90  IKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKH 149
           I+ + +       ++HC             + K V  +++EIE++K   +KL+Q    K 
Sbjct: 353 IRHLDD-------MVHC-------------QQKKVKQMVEEIESLK---KKLQQ----KQ 385

Query: 150 YLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSK 184
            L     L+  +  LEG   +++   D   E  +K
Sbjct: 386 LLIL--QLLEKISFLEGENNELQSRLDYLTETQAK 418


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.352 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,699,797
Number of Sequences: 37866
Number of extensions: 648542
Number of successful extensions: 2192
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 86
Number of HSP's that attempted gapping in prelim test: 2139
Number of HSP's gapped (non-prelim): 150
length of query: 473
length of database: 18,247,518
effective HSP length: 106
effective length of query: 367
effective length of database: 14,233,722
effective search space: 5223775974
effective search space used: 5223775974
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.