Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 81158226
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|81158226 neuronal cell adhesion molecule isoform A precursor
[Homo sapiens]
(1304 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|81158226 neuronal cell adhesion molecule isoform A precursor ... 2655 0.0
gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 2096 0.0
gi|237858675 neurofascin isoform 1 precursor [Homo sapiens] 1096 0.0
gi|237858677 neurofascin isoform 2 precursor [Homo sapiens] 1037 0.0
gi|237858679 neurofascin isoform 3 precursor [Homo sapiens] 1032 0.0
gi|89903008 neurofascin isoform 4 precursor [Homo sapiens] 1032 0.0
gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo... 918 0.0
gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo ... 913 0.0
gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo s... 912 0.0
gi|27894376 cell adhesion molecule with homology to L1CAM precur... 879 0.0
gi|237858680 neurofascin isoform 5 precursor [Homo sapiens] 672 0.0
gi|237858682 neurofascin isoform 6 precursor [Homo sapiens] 662 0.0
gi|4827022 contactin 2 precursor [Homo sapiens] 372 e-102
gi|75709184 contactin 3 [Homo sapiens] 365 e-100
gi|28373129 contactin 5 isoform short [Homo sapiens] 358 2e-98
gi|7657359 contactin 5 isoform long [Homo sapiens] 358 2e-98
gi|28373122 contactin 4 isoform a precursor [Homo sapiens] 352 1e-96
gi|7657361 contactin 6 [Homo sapiens] 333 5e-91
gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens] 308 2e-83
gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens] 308 2e-83
gi|119220552 sidekick 1 [Homo sapiens] 272 2e-72
gi|28373126 contactin 4 isoform c precursor [Homo sapiens] 265 3e-70
gi|222352127 sidekick 2 [Homo sapiens] 264 5e-70
gi|157311649 neogenin homolog 1 [Homo sapiens] 229 2e-59
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa... 224 4e-58
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 221 3e-57
gi|110431348 deleted in colorectal carcinoma [Homo sapiens] 218 3e-56
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 211 5e-54
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 209 1e-53
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 198 2e-50
>gi|81158226 neuronal cell adhesion molecule isoform A precursor [Homo
sapiens]
Length = 1304
Score = 2655 bits (6882), Expect = 0.0
Identities = 1304/1304 (100%), Positives = 1304/1304 (100%)
Query: 1 MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDP 60
MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDP
Sbjct: 1 MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDP 60
Query: 61 RENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 120
RENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV
Sbjct: 61 RENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 120
Query: 121 YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW 180
YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW
Sbjct: 121 YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW 180
Query: 181 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVIS 240
MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVIS
Sbjct: 181 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVIS 240
Query: 241 VDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP 300
VDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP
Sbjct: 241 VDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP 300
Query: 301 IIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA 360
IIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA
Sbjct: 301 IIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA 360
Query: 361 PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFS 420
PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFS
Sbjct: 361 PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFS 420
Query: 421 NVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFG 480
NVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFG
Sbjct: 421 NVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFG 480
Query: 481 SPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL 540
SPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL
Sbjct: 481 SPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL 540
Query: 541 EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH 600
EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH
Sbjct: 541 EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH 600
Query: 601 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLD 660
LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLD
Sbjct: 601 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLD 660
Query: 661 KSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFR 720
KSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFR
Sbjct: 661 KSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFR 720
Query: 721 VMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGL 780
VMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGL
Sbjct: 721 VMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGL 780
Query: 781 QYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHS 840
QYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHS
Sbjct: 781 QYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHS 840
Query: 841 GEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIE 900
GEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIE
Sbjct: 841 GEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIE 900
Query: 901 KKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKI 960
KKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKI
Sbjct: 901 KKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKI 960
Query: 961 VNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNF 1020
VNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNF
Sbjct: 961 VNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNF 1020
Query: 1021 STRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAET 1080
STRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAET
Sbjct: 1021 STRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAET 1080
Query: 1081 YANISWEYEGPEHVNFYVEYGVAGSKEEWRKEIVNGSRSFFGLKGLMPGTAYKVRVGAVG 1140
YANISWEYEGPEHVNFYVEYGVAGSKEEWRKEIVNGSRSFFGLKGLMPGTAYKVRVGAVG
Sbjct: 1081 YANISWEYEGPEHVNFYVEYGVAGSKEEWRKEIVNGSRSFFGLKGLMPGTAYKVRVGAVG 1140
Query: 1141 DSGFVSSEDVFETGPAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPV 1200
DSGFVSSEDVFETGPAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPV
Sbjct: 1141 DSGFVSSEDVFETGPAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPV 1200
Query: 1201 KEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGE 1260
KEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGE
Sbjct: 1201 KEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGE 1260
Query: 1261 GVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNSFV 1304
GVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNSFV
Sbjct: 1261 GVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNSFV 1304
>gi|81158224 neuronal cell adhesion molecule isoform B precursor [Homo
sapiens]
Length = 1183
Score = 2096 bits (5430), Expect = 0.0
Identities = 1035/1051 (98%), Positives = 1035/1051 (98%), Gaps = 16/1051 (1%)
Query: 1 MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDP 60
MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLD LVQPPTITQQSPKDYIIDP
Sbjct: 1 MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLD------LVQPPTITQQSPKDYIIDP 54
Query: 61 RENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 120
RENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV
Sbjct: 55 RENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 114
Query: 121 YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW 180
YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW
Sbjct: 115 YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW 174
Query: 181 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVIS 240
MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVIS
Sbjct: 175 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVIS 234
Query: 241 VDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP 300
VDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP
Sbjct: 235 VDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP 294
Query: 301 IIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA 360
IIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA
Sbjct: 295 IIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA 354
Query: 361 PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFS 420
PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFS
Sbjct: 355 PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFS 414
Query: 421 NVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFG 480
NVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFG
Sbjct: 415 NVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFG 474
Query: 481 SPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL 540
SPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL
Sbjct: 475 SPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL 534
Query: 541 EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH 600
EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH
Sbjct: 535 EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH 594
Query: 601 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLD 660
LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVV DVPNPPFDLELTDQLD
Sbjct: 595 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVV----------DVPNPPFDLELTDQLD 644
Query: 661 KSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFR 720
KSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFR
Sbjct: 645 KSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFR 704
Query: 721 VMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGL 780
VMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGL
Sbjct: 705 VMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGL 764
Query: 781 QYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHS 840
QYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHS
Sbjct: 765 QYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHS 824
Query: 841 GEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIE 900
GEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIE
Sbjct: 825 GEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIE 884
Query: 901 KKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKI 960
KKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKI
Sbjct: 885 KKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKI 944
Query: 961 VNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNF 1020
VNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNF
Sbjct: 945 VNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNF 1004
Query: 1021 STRYKFYFYAQTSAGSGSQITEEAVTTVDEA 1051
STRYKFYFYAQTSAGSGSQITEEAVTTVDEA
Sbjct: 1005 STRYKFYFYAQTSAGSGSQITEEAVTTVDEA 1035
Score = 363 bits (933), Expect = e-100
Identities = 343/1095 (31%), Positives = 474/1095 (43%), Gaps = 140/1095 (12%)
Query: 285 GNVLSLECIAE-GLPTPIIYWAKEDGM-LPKNRTVYKNFEKTLQIIHVSEADSG-NYQCI 341
G L L C GLP PII+W LP++ V + L +V D+ +Y C
Sbjct: 154 GQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICY 213
Query: 342 AKNALGAIHHT--------ISVRV--------------------------KAAPYWITAP 367
A+ +HT ISV+V + P ++T
Sbjct: 214 AR-----FNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPE 268
Query: 368 QNLVLSPGEDGTLI---CRANGNPKPRISWLT-NGVPIEIAPDDPSRKIDGDTIIFSNVQ 423
N G ++ C A G P P I W +G+ + + K T+ +V
Sbjct: 269 GNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGM---LPKNRTVYKNFEKTLQIIHVS 325
Query: 424 ERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPL 483
E S YQC A N G + V V A P I P N + L C G+P
Sbjct: 326 EADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLS--PGEDGTLICRANGNPK 383
Query: 484 PTIEWF-KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLG--MAKNEVHL 540
P I W G +D + T+ Q+ S+ Y C A N+ G +A V++
Sbjct: 384 PRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNV 443
Query: 541 EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV--DK 598
+ P + V +C T+ W K + E V +
Sbjct: 444 LAEPPRILTPANTLYQVIANRPALLDCAFFGSPLP--TIEWFKGAKGSALHEDIYVLHEN 501
Query: 599 DHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPT-----PTPAPVYDVPNPPFDL 653
L + D +GTYTCVA L L + PT P A V F+
Sbjct: 502 GTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFEC 561
Query: 654 ELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSP 713
++ S+ + W + +F ++ + + + + SGT T
Sbjct: 562 KVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLV----VADVSDDDSGTYTCVA----- 612
Query: 714 YVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGF 773
+L S ++ L+ P+ P +E ++ ++W P G
Sbjct: 613 --------------NTTLDSVSASAVLSVVDVPNP-PFDLELTDQLDKSVQLSWTP--GD 655
Query: 774 ESNGPGLQYKVSWRQ---KDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFA 830
++N P ++ + + K G + V + + +P +V Y +V A+N +G +
Sbjct: 656 DNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSP-YVNYSFRVMAVNSIGKS 714
Query: 831 -PEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQ 889
P A + P P V + W P+ G Y++ W+ +
Sbjct: 715 LPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVS-WRQK 773
Query: 890 SSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPE 949
+ + + ++ G F Y + V+ +N G P + ++ E
Sbjct: 774 DGDDEWTSVVVANVSKY-------IVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGE 826
Query: 950 GVPS-APSSLKI--VNPTLDSLTLEWDPPSHPN--GILTEYTLKYQPINSTHELGPL-VD 1003
+P AP ++++ VN TL + WDP + G L Y + Y S+ + ++
Sbjct: 827 DLPMVAPGNVRVNVVNSTLAEV--HWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIE 884
Query: 1004 LKI---PANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGA 1060
KI +KT L L + Y G G + T + P
Sbjct: 885 KKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAP----- 939
Query: 1061 GKVQAVNPRISNLTAAAAETYANISWEYEGPEHVN-----FYVEYGVAGSKEEWRKEI-- 1113
++ VNP + +LT E++ P H N + ++Y S E +
Sbjct: 940 SSLKIVNPTLDSLTL-----------EWDPPSHPNGILTEYTLKYQPINSTHELGPLVDL 988
Query: 1114 -VNGSRSFFGLKGLMPGTAYKVRVGA---VGDSGFVSSEDVFETGPAMASRQVDIATQGW 1169
+ +++ + LK L T YK A G ++ E V AMASRQVDIATQGW
Sbjct: 989 KIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMASRQVDIATQGW 1048
Query: 1170 FIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAE 1229
FIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAE
Sbjct: 1049 FIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAE 1108
Query: 1230 DHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGNE 1289
DHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGNE
Sbjct: 1109 DHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGNE 1168
Query: 1290 SSEAPSPVNAMNSFV 1304
SSEAPSPVNAMNSFV
Sbjct: 1169 SSEAPSPVNAMNSFV 1183
>gi|237858675 neurofascin isoform 1 precursor [Homo sapiens]
Length = 1240
Score = 1096 bits (2834), Expect = 0.0
Identities = 603/1301 (46%), Positives = 806/1301 (61%), Gaps = 95/1301 (7%)
Query: 20 ILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFS 79
+L L + A+E+P+DP + +L QPPTIT+QS KD+I+DPR+NI+I+CEAKG P PSF
Sbjct: 15 LLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFH 74
Query: 80 WTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 139
WTRN F+I KDP V+M+ +GTL+I+ S G+ E YEG YQC ARN+ G A+SN I +
Sbjct: 75 WTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRL 134
Query: 140 RPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLN 199
+ S+SPLW KE L+P+ +Q G L L C PP GLP P+IFWM +S + + Q +RVSQG N
Sbjct: 135 QVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHN 194
Query: 200 GDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYG 259
GDLYFSNV+ +D + DY C ARF+ T TIQQK P ++KV++
Sbjct: 195 GDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTT------------------ 236
Query: 260 AKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK 319
+ ER P+F+ P+G AS++ LRG L LECIA G+PTP I W K+ G LP ++ ++
Sbjct: 237 -RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFE 295
Query: 320 NFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT 379
NF K L+I +VSE DSG Y C+A N +G+I HTISVRVKAAPYW+ P+NL+L+PGEDG
Sbjct: 296 NFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGR 355
Query: 380 LICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYG 439
L+CRANGNPKP + W+ NG P++ AP +P+R++ GDTIIF + Q S AVYQCN SNE+G
Sbjct: 356 LVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 415
Query: 440 YLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE 499
YLLANAFV+VL PPR+L+P N L +VI LDC FFGSP+PT+ WFK +GS L
Sbjct: 416 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG 475
Query: 500 DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 559
Y ++ENG+LEI + +K+ G YTCVA N LG A+N+V LE+KDPT I + PE V +R
Sbjct: 476 GNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARR 535
Query: 560 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVAN 619
G+ V EC+VKHD +L LTV WLKD+ L R + D L + V++ D G+YTCVA+
Sbjct: 536 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVAS 595
Query: 620 TTLDSVSASAVLSVVAPTPTP-----APVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNN 674
T LD A A L+V+A TP A P+ P DLELTD ++SV+L+W PGD NN
Sbjct: 596 TELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANN 655
Query: 675 SPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSE 734
SPIT +++++E+ +PG+WH ++ G+ +A L+LSPYVNY FRV+A+N +G S PS
Sbjct: 656 SPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSL 715
Query: 735 ASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDE 794
SE+Y T + P+ NP V+G G+ +N+ ITW P+N + GP L+Y V WR+++ +
Sbjct: 716 PSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREA 775
Query: 795 WTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRV 854
W +V V S+Y+V TP +VPY I+VQA ND G PEP V+G+SGEDLP AP RV
Sbjct: 776 WNNVTVWG-SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPS-APRRFRV 833
Query: 855 NVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGM 914
N + WD + G + GY + Y + +K ++ +E F ++T
Sbjct: 834 RQPNLETINLEWDHP--EHPNGIMIGYTLKY-VAFNGTKVGKQIVE----NFSPNQTKFT 886
Query: 915 LPGLEPFSHY--TLNVRVVNGKG-----EGPASPDRVFNTPEGVPSAPSSLKIVNPTLDS 967
+ +P S Y TL+ R G G E PA P+ TP P PTL
Sbjct: 887 VQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEA--TPTAAP----------PTL-- 932
Query: 968 LTLEWDPPSHPNGILTEYTLKYQPINSTHELG--PLVDLKIPANKTRWTLKNLNFSTRYK 1025
PP+ + I +T E P++ P
Sbjct: 933 ------PPTTVGATGAVSSTDATAIAATTEATTVPIIPTVAPTT---------------- 970
Query: 1026 FYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAG-KVQAVNP---RISNLTAAAAETY 1081
A T+ + + T A TT E+ PP +G K+ P I N+T +
Sbjct: 971 ---IATTTTVATTTTTTAAATTTTES---PPTTTSGTKIHESAPDEQSIWNVTVLPNSKW 1024
Query: 1082 ANISWEYEGPEHVNFYVEYGVAGSKEEWRKEIVNGSRSFFGLKGLMPGTAYKVRVGAVGD 1141
ANI+W++ +F VEY S + V L L PG Y +RV + +
Sbjct: 1025 ANITWKHNFGPGTDFVVEY--IDSNHTKKTVPVKAQAQPIQLTDLYPGMTYTLRVYSRDN 1082
Query: 1142 SGFVSSEDVFETGPAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVK 1201
G S+ F T A + Q DIATQGWFIGLMCA+ALL+LILLIVCFI+R++GGKYPV+
Sbjct: 1083 EGISSTVITFMTSTAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVR 1142
Query: 1202 EKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEG 1261
EK+D PE KE+DG+F +YSD ED+KPL +GS+T D T+K+++SDDSLVDYGEG
Sbjct: 1143 EKKDVPLGPE--DPKEEDGSF-DYSD-EDNKPL-QGSQTSLDGTIKQQESDDSLVDYGEG 1197
Query: 1262 VNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNS 1302
GQFNEDGSFIGQY+ KK+KE EGNESSEA SPVNA+ S
Sbjct: 1198 GEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYS 1238
>gi|237858677 neurofascin isoform 2 precursor [Homo sapiens]
Length = 1189
Score = 1037 bits (2681), Expect = 0.0
Identities = 511/1037 (49%), Positives = 698/1037 (67%), Gaps = 15/1037 (1%)
Query: 20 ILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFS 79
+L L + A+E+P+D L QPPTIT+QS KD+I+DPR+NI+I+CEAKG P PSF
Sbjct: 15 LLCLLSLGGAIEIPMD------LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFH 68
Query: 80 WTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 139
WTRN F+I KDP V+M+ +GTL+I+ S G+ E YEG YQC ARN+ G A+SN I +
Sbjct: 69 WTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRL 128
Query: 140 RPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLN 199
+ S+SPLW KE L+P+ +Q G L L C PP GLP P+IFWM +S + + Q +RVSQG N
Sbjct: 129 QVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHN 188
Query: 200 GDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYG 259
GDLYFSNV+ +D + DY C ARF+ T TIQQK P ++KV++ ND+ N D Y
Sbjct: 189 GDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPD--MYS 246
Query: 260 AKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK 319
A+ ER P+F+ P+G AS++ LRG L LECIA G+PTP I W K+ G LP ++ ++
Sbjct: 247 ARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFE 306
Query: 320 NFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT 379
NF K L+I +VSE DSG Y C+A N +G+I HTISVRVKAAPYW+ P+NL+L+PGEDG
Sbjct: 307 NFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGR 366
Query: 380 LICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYG 439
L+CRANGNPKP + W+ NG P++ AP +P+R++ GDTIIF + Q S AVYQCN SNE+G
Sbjct: 367 LVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 426
Query: 440 YLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE 499
YLLANAFV+VL PPR+L+P N L +VI LDC FFGSP+PT+ WFK +GS L
Sbjct: 427 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG 486
Query: 500 DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 559
Y ++ENG+LEI + +K+ G YTCVA N LG A+N+V LE+KDPT I + PE V +R
Sbjct: 487 GNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARR 546
Query: 560 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVAN 619
G+ V EC+VKHD +L LTV WLKD+ L R + D L + V++ D G+YTCVA+
Sbjct: 547 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVAS 606
Query: 620 TTLDSVSASAVLSVVAPTPTP-----APVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNN 674
T LD A A L+V+A TP A P+ P DLELTD ++SV+L+W PGD NN
Sbjct: 607 TELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANN 666
Query: 675 SPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSE 734
SPIT +++++E+ +PG+WH ++ G+ +A L+LSPYVNY FRV+A+N +G S PS
Sbjct: 667 SPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSL 726
Query: 735 ASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDE 794
SE+Y T + P+ NP V+G G+ +N+ ITW P+N + GP L+Y V WR+++ +
Sbjct: 727 PSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREA 786
Query: 795 WTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRV 854
W +V V S+Y+V TP +VPY I+VQA ND G PEP V+G+SGED P AP V+V
Sbjct: 787 WNNVTVWG-SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKV 845
Query: 855 NVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGM 914
V+NST + W+ V +++G L+ YR YYW+ S K +++ +F G + G+
Sbjct: 846 RVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGV 905
Query: 915 LPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDP 974
+ L P+S+Y L + VVNG+G+GP S + F TPEGVPSAP ++ P L+++ LEWD
Sbjct: 906 VSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDH 965
Query: 975 PSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSA 1034
P HPNGI+ YTLKY N T ++G + N+T++T++ + +RY+F A+T
Sbjct: 966 PEHPNGIMIGYTLKYVAFNGT-KVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQV 1024
Query: 1035 GSGSQITEEAVTTVDEA 1051
GSG +TEE+ +EA
Sbjct: 1025 GSGEAVTEESPAPPNEA 1041
Score = 283 bits (724), Expect = 8e-76
Identities = 338/1258 (26%), Positives = 522/1258 (41%), Gaps = 199/1258 (15%)
Query: 142 SRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNS-FQRLPQSERVS-QGLN 199
++ P TK+ + + ++++ C G P P W NS F + + RVS + +
Sbjct: 32 TQPPTITKQSAKDHIVDPRDNILIECEAK-GNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 90
Query: 200 GDL---YFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTE 256
G L + S PE+ +Y C+AR + + + V
Sbjct: 91 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQV-------------------- 130
Query: 257 FYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAE-GLPTPIIYWAKED-GMLPKN 314
+KS L P+ N G L+L+C GLP+P+I+W + ++
Sbjct: 131 ---SKSP-------LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD 180
Query: 315 RTVYKNFEKTLQIIHVSEAD-SGNYQCIAKNALGAIHHTISVR----------------- 356
+ V + L +V D +Y C NA HTI +
Sbjct: 181 KRVSQGHNGDLYFSNVMLQDMQTDYSC---NARFHFTHTIQQKNPFTLKVLTNHPYNDSS 237
Query: 357 -------------VKAAPYWI----TAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGV 399
+ P ++ TA +VL G D L C A+G P P I+W G
Sbjct: 238 LRNHPDMYSARGVAERTPSFMYPQGTASSQMVLR-GMDLLLECIASGVPTPDIAWYKKGG 296
Query: 400 PIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILT 458
+ P D ++ + + + +NV E S Y C ASN+ G + V V A P +
Sbjct: 297 DL---PSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDE 353
Query: 459 PANTLYQVIANRPALLDCAFFGSPLPTIEWF-KGAKGSALHEDIYVLHENGTLEIPVAQK 517
P N + + L C G+P PT++W G + + T+ Q
Sbjct: 354 PKNLI--LAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQI 411
Query: 518 DSTGTYTCVARNKLGMAKNEVHLEIKD--PTWIVKQPEYAVVQRGSMVSFECKVKHDHTL 575
S Y C N+ G + + D P + + + V + +C
Sbjct: 412 SSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIP 471
Query: 576 SLTVLWLKDNR--ELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 633
+L W K+ + L + L + + +D G YTCVA L L V
Sbjct: 472 TLR--WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV 529
Query: 634 VAPTPTPAPVYDVPNPPF-------DLELTDQLDKSVQL--SWTPGDDNNSPITKFIIEY 684
PT +Y +P LE + D S++L SW DD I + +
Sbjct: 530 KDPTR----IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLK-DDEPLYIGNRMKKE 584
Query: 685 EDAMHKPGLWHHQ----TEVSGT---QTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASE 737
+D++ G+ T V+ T Q A+ L+ + + + ++ K P +
Sbjct: 585 DDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRD 644
Query: 738 QYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTS 797
LT +E ++ +TW P G +N P Y V + + D++
Sbjct: 645 LELTDLAER---------------SVRLTWIP--GDANNSPITDYVVQFEE----DQFQP 683
Query: 798 VVVANVSKY------IVSGTPTFVPYLIKVQALNDMGFAPE--PAVVMGHSGEDLPMVAP 849
V + SKY V +V Y +V A+N++G + P+ SG P P
Sbjct: 684 GVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAP-PESNP 742
Query: 850 GNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGS 909
G+V+ E+ W P+ S G Y I W+ +R R + +
Sbjct: 743 GDVKGEGTRKNNMEITWTPMNATSAFGPNLRY-IVKWR-----RRETREAWNNVTVWGSR 796
Query: 910 KTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVP-SAPSSLKIVNPTLDSL 968
G P P Y + V+ N G+GP + + E P +AP+ +K+ ++
Sbjct: 797 YVVGQTPVYVP---YEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAI 853
Query: 969 TLEWDP--PSHPNGILTEYTLKYQPINSTHE----LGPLVDLKIPANKTRWTLKNLNFST 1022
+L+W+ G L EY Y +S + P ++ R + L +
Sbjct: 854 SLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYS 913
Query: 1023 RYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYA 1082
YK G G + + TT + P + + P + +
Sbjct: 914 NYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPR-----RFRVRQPNLETI--------- 959
Query: 1083 NISWEYEGPEHVN-----FYVEYGVAGSKEEWRKEIVNG---SRSFFGLKGLMPGTAYKV 1134
N+ W++ PEH N + ++Y VA + + K+IV +++ F ++ P + Y+
Sbjct: 960 NLEWDH--PEHPNGIMIGYTLKY-VAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRF 1016
Query: 1135 RVGAVGDSGFVSSEDVFETGPA----------MASRQVDIATQGWFIGLMCAVALLILIL 1184
+ A G S E V E PA + Q DIATQGWFIGLMCA+ALL+LIL
Sbjct: 1017 TLSARTQVG--SGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIALLVLIL 1074
Query: 1185 LIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDR 1244
LIVCFI+R++GGKYPV+EK+D PE KE+DG+F +YSD ED+KPL+ GS+T D
Sbjct: 1075 LIVCFIKRSRGGKYPVREKKDVPLGPE--DPKEEDGSF-DYSD-EDNKPLQ-GSQTSLDG 1129
Query: 1245 TVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNS 1302
T+K+++SDDSLVDYGEG GQFNEDGSFIGQY+ KK+KE EGNESSEA SPVNA+ S
Sbjct: 1130 TIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYS 1187
>gi|237858679 neurofascin isoform 3 precursor [Homo sapiens]
Length = 1174
Score = 1032 bits (2668), Expect = 0.0
Identities = 507/1032 (49%), Positives = 694/1032 (67%), Gaps = 20/1032 (1%)
Query: 20 ILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFS 79
+L L + A+E+P+D L QPPTIT+QS KD+I+DPR+NI+I+CEAKG P PSF
Sbjct: 15 LLCLLSLGGAIEIPMD------LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFH 68
Query: 80 WTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 139
WTRN F+I KDP V+M+ +GTL+I+ S G+ E YEG YQC ARN+ G A+SN I +
Sbjct: 69 WTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRL 128
Query: 140 RPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLN 199
+ S+SPLW KE L+P+ +Q G L L C PP GLP P+IFWM +S + + Q +RVSQG N
Sbjct: 129 QVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHN 188
Query: 200 GDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYG 259
GDLYFSNV+ +D + DY C ARF+ T TIQQK P ++KV++ ND+ N D Y
Sbjct: 189 GDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPD--MYS 246
Query: 260 AKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK 319
A+ ER P+F+ P+G AS++ LRG L LECIA G+PTP I W K+ G LP ++ ++
Sbjct: 247 ARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFE 306
Query: 320 NFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT 379
NF K L+I +VSE DSG Y C+A N +G+I HTISVRVKAAPYW+ P+NL+L+PGEDG
Sbjct: 307 NFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGR 366
Query: 380 LICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYG 439
L+CRANGNPKP + W+ NG P++ AP +P+R++ GDTIIF + Q S AVYQCN SNE+G
Sbjct: 367 LVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 426
Query: 440 YLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE 499
YLLANAFV+VL PPR+L+P N L +VI LDC FFGSP+PT+ WFK +GS L
Sbjct: 427 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG 486
Query: 500 DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 559
Y ++ENG+LEI + +K+ G YTCVA N LG A+N+V LE+KDPT I + PE V +R
Sbjct: 487 GNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARR 546
Query: 560 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVAN 619
G+ V EC+VKHD +L LTV WLKD+ L R + D L + V++ D G+YTCVA+
Sbjct: 547 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVAS 606
Query: 620 TTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITK 679
T LD A A L+V+ P+ P DLELTD ++SV+L+W PGD NNSPIT
Sbjct: 607 TELDQDLAKAYLTVLGR----------PDRPRDLELTDLAERSVRLTWIPGDANNSPITD 656
Query: 680 FIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQY 739
+++++E+ +PG+WH ++ G+ +A L+LSPYVNY FRV+A+N +G S PS SE+Y
Sbjct: 657 YVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERY 716
Query: 740 LTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVV 799
T + P+ NP V+G G+ +N+ ITW P+N + GP L+Y V WR+++ + W +V
Sbjct: 717 RTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVT 776
Query: 800 VANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNS 859
V S+Y+V TP +VPY I+VQA ND G PEP V+G+SGED P AP V+V V+NS
Sbjct: 777 VWG-SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNS 835
Query: 860 TLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLE 919
T + W+ V +++G L+ YR YYW+ S K +++ +F G + G++ L
Sbjct: 836 TAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLF 895
Query: 920 PFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPN 979
P+S+Y L + VVNG+G+GP S + F TPEGVPSAP ++ P L+++ LEWD P HPN
Sbjct: 896 PYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPN 955
Query: 980 GILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQ 1039
GI+ YTLKY N T ++G + N+T++T++ + +RY+F A+T GSG
Sbjct: 956 GIMIGYTLKYVAFNGT-KVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEA 1014
Query: 1040 ITEEAVTTVDEA 1051
+TEE+ +EA
Sbjct: 1015 VTEESPAPPNEA 1026
Score = 288 bits (736), Expect = 3e-77
Identities = 332/1245 (26%), Positives = 517/1245 (41%), Gaps = 188/1245 (15%)
Query: 142 SRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNS-FQRLPQSERVS-QGLN 199
++ P TK+ + + ++++ C G P P W NS F + + RVS + +
Sbjct: 32 TQPPTITKQSAKDHIVDPRDNILIECEAK-GNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 90
Query: 200 GDL---YFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTE 256
G L + S PE+ +Y C+AR + + + V
Sbjct: 91 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQV-------------------- 130
Query: 257 FYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAE-GLPTPIIYWAKED-GMLPKN 314
+KS L P+ N G L+L+C GLP+P+I+W + ++
Sbjct: 131 ---SKSP-------LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD 180
Query: 315 RTVYKNFEKTLQIIHVSEAD-SGNYQCIAKNALGAIHHTISVR----------------- 356
+ V + L +V D +Y C NA HTI +
Sbjct: 181 KRVSQGHNGDLYFSNVMLQDMQTDYSC---NARFHFTHTIQQKNPFTLKVLTNHPYNDSS 237
Query: 357 -------------VKAAPYWI----TAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGV 399
+ P ++ TA +VL G D L C A+G P P I+W G
Sbjct: 238 LRNHPDMYSARGVAERTPSFMYPQGTASSQMVLR-GMDLLLECIASGVPTPDIAWYKKGG 296
Query: 400 PIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILT 458
+ P D ++ + + + +NV E S Y C ASN+ G + V V A P +
Sbjct: 297 DL---PSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDE 353
Query: 459 PANTLYQVIANRPALLDCAFFGSPLPTIEWF-KGAKGSALHEDIYVLHENGTLEIPVAQK 517
P N + + L C G+P PT++W G + + T+ Q
Sbjct: 354 PKNLI--LAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQI 411
Query: 518 DSTGTYTCVARNKLGMAKNEVHLEIKD--PTWIVKQPEYAVVQRGSMVSFECKVKHDHTL 575
S Y C N+ G + + D P + + + V + +C
Sbjct: 412 SSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIP 471
Query: 576 SLTVLWLKDNR--ELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 633
+L W K+ + L + L + + +D G YTCVA L L V
Sbjct: 472 TLR--WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV 529
Query: 634 VAPTPTPAPVYDVPNPPFDLELTDQLDK---SVQLSWTPGDDNNSPITKFIIEYEDAMHK 690
PT +Y +P DQ+ + +VQL D + +T ++ ++ ++
Sbjct: 530 KDPTR----IYRMPE--------DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYI 577
Query: 691 PGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNP 750
+ + A+ Y + L + ++ YLT PD+ P
Sbjct: 578 GNRMKKEDDSLTIFGVAERDQGSYTCVA---------STELDQDLAKAYLTVLGRPDR-P 627
Query: 751 TAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKY---- 806
+E ++ +TW P G +N P Y V + + D++ V + SKY
Sbjct: 628 RDLELTDLAERSVRLTWIP--GDANNSPITDYVVQFEE----DQFQPGVWHDHSKYPGSV 681
Query: 807 --IVSGTPTFVPYLIKVQALNDMGFAPE--PAVVMGHSGEDLPMVAPGNVRVNVVNSTLA 862
V +V Y +V A+N++G + P+ SG P PG+V+
Sbjct: 682 NSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAP-PESNPGDVKGEGTRKNNM 740
Query: 863 EVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFS 922
E+ W P+ S G Y I W+ +R R + + G P P
Sbjct: 741 EITWTPMNATSAFGPNLRY-IVKWR-----RRETREAWNNVTVWGSRYVVGQTPVYVP-- 792
Query: 923 HYTLNVRVVNGKGEGPASPDRVFNTPEGVP-SAPSSLKIVNPTLDSLTLEWDP--PSHPN 979
Y + V+ N G+GP + + E P +AP+ +K+ +++L+W+
Sbjct: 793 -YEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQ 851
Query: 980 GILTEYTLKYQPINSTHE----LGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAG 1035
G L EY Y +S + P ++ R + L + YK G
Sbjct: 852 GQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRG 911
Query: 1036 SGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISWEYEGPEHVN 1095
G + + TT + P + + P + + N+ W++ PEH N
Sbjct: 912 DGPRSETKEFTTPEGVPSAPR-----RFRVRQPNLETI---------NLEWDH--PEHPN 955
Query: 1096 -----FYVEYGVAGSKEEWRKEIVNG---SRSFFGLKGLMPGTAYKVRVGAVGDSGFVSS 1147
+ ++Y VA + + K+IV +++ F ++ P + Y+ + A G S
Sbjct: 956 GIMIGYTLKY-VAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVG--SG 1012
Query: 1148 EDVFETGPA----------MASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGK 1197
E V E PA + Q DIATQGWFIGLMCA+ALL+LILLIVCFI+R++GGK
Sbjct: 1013 EAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGK 1072
Query: 1198 YPVKEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVD 1257
YPV+EK+D PE KE+DG+F +YSD ED+KPL+ GS+T D T+K+++SDDSLVD
Sbjct: 1073 YPVREKKDVPLGPE--DPKEEDGSF-DYSD-EDNKPLQ-GSQTSLDGTIKQQESDDSLVD 1127
Query: 1258 YGEGVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNS 1302
YGEG GQFNEDGSFIGQY+ KK+KE EGNESSEA SPVNA+ S
Sbjct: 1128 YGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYS 1172
>gi|89903008 neurofascin isoform 4 precursor [Homo sapiens]
Length = 1169
Score = 1032 bits (2668), Expect = 0.0
Identities = 507/1032 (49%), Positives = 694/1032 (67%), Gaps = 20/1032 (1%)
Query: 20 ILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFS 79
+L L + A+E+P+D L QPPTIT+QS KD+I+DPR+NI+I+CEAKG P PSF
Sbjct: 15 LLCLLSLGGAIEIPMD------LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFH 68
Query: 80 WTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 139
WTRN F+I KDP V+M+ +GTL+I+ S G+ E YEG YQC ARN+ G A+SN I +
Sbjct: 69 WTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRL 128
Query: 140 RPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLN 199
+ S+SPLW KE L+P+ +Q G L L C PP GLP P+IFWM +S + + Q +RVSQG N
Sbjct: 129 QVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHN 188
Query: 200 GDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYG 259
GDLYFSNV+ +D + DY C ARF+ T TIQQK P ++KV++ ND+ N D Y
Sbjct: 189 GDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPD--MYS 246
Query: 260 AKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK 319
A+ ER P+F+ P+G AS++ LRG L LECIA G+PTP I W K+ G LP ++ ++
Sbjct: 247 ARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFE 306
Query: 320 NFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT 379
NF K L+I +VSE DSG Y C+A N +G+I HTISVRVKAAPYW+ P+NL+L+PGEDG
Sbjct: 307 NFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGR 366
Query: 380 LICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYG 439
L+CRANGNPKP + W+ NG P++ AP +P+R++ GDTIIF + Q S AVYQCN SNE+G
Sbjct: 367 LVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 426
Query: 440 YLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE 499
YLLANAFV+VL PPR+L+P N L +VI LDC FFGSP+PT+ WFK +GS L
Sbjct: 427 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG 486
Query: 500 DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 559
Y ++ENG+LEI + +K+ G YTCVA N LG A+N+V LE+KDPT I + PE V +R
Sbjct: 487 GNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARR 546
Query: 560 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVAN 619
G+ V EC+VKHD +L LTV WLKD+ L R + D L + V++ D G+YTCVA+
Sbjct: 547 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVAS 606
Query: 620 TTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITK 679
T LD A A L+V+ P+ P DLELTD ++SV+L+W PGD NNSPIT
Sbjct: 607 TELDQDLAKAYLTVLGR----------PDRPRDLELTDLAERSVRLTWIPGDANNSPITD 656
Query: 680 FIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQY 739
+++++E+ +PG+WH ++ G+ +A L+LSPYVNY FRV+A+N +G S PS SE+Y
Sbjct: 657 YVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERY 716
Query: 740 LTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVV 799
T + P+ NP V+G G+ +N+ ITW P+N + GP L+Y V WR+++ + W +V
Sbjct: 717 RTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVT 776
Query: 800 VANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNS 859
V S+Y+V TP +VPY I+VQA ND G PEP V+G+SGED P AP V+V V+NS
Sbjct: 777 VWG-SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNS 835
Query: 860 TLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLE 919
T + W+ V +++G L+ YR YYW+ S K +++ +F G + G++ L
Sbjct: 836 TAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLF 895
Query: 920 PFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPN 979
P+S+Y L + VVNG+G+GP S + F TPEGVPSAP ++ P L+++ LEWD P HPN
Sbjct: 896 PYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPN 955
Query: 980 GILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQ 1039
GI+ YTLKY N T ++G + N+T++T++ + +RY+F A+T GSG
Sbjct: 956 GIMIGYTLKYVAFNGT-KVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEA 1014
Query: 1040 ITEEAVTTVDEA 1051
+TEE+ +EA
Sbjct: 1015 VTEESPAPPNEA 1026
Score = 291 bits (746), Expect = 2e-78
Identities = 330/1238 (26%), Positives = 516/1238 (41%), Gaps = 179/1238 (14%)
Query: 142 SRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNS-FQRLPQSERVS-QGLN 199
++ P TK+ + + ++++ C G P P W NS F + + RVS + +
Sbjct: 32 TQPPTITKQSAKDHIVDPRDNILIECEAK-GNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 90
Query: 200 GDL---YFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTE 256
G L + S PE+ +Y C+AR + + + V
Sbjct: 91 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQV-------------------- 130
Query: 257 FYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAE-GLPTPIIYWAKED-GMLPKN 314
+KS L P+ N G L+L+C GLP+P+I+W + ++
Sbjct: 131 ---SKSP-------LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD 180
Query: 315 RTVYKNFEKTLQIIHVSEAD-SGNYQCIAKNALGAIHHTISVR----------------- 356
+ V + L +V D +Y C NA HTI +
Sbjct: 181 KRVSQGHNGDLYFSNVMLQDMQTDYSC---NARFHFTHTIQQKNPFTLKVLTNHPYNDSS 237
Query: 357 -------------VKAAPYWI----TAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGV 399
+ P ++ TA +VL G D L C A+G P P I+W G
Sbjct: 238 LRNHPDMYSARGVAERTPSFMYPQGTASSQMVLR-GMDLLLECIASGVPTPDIAWYKKGG 296
Query: 400 PIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILT 458
+ P D ++ + + + +NV E S Y C ASN+ G + V V A P +
Sbjct: 297 DL---PSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDE 353
Query: 459 PANTLYQVIANRPALLDCAFFGSPLPTIEWF-KGAKGSALHEDIYVLHENGTLEIPVAQK 517
P N + + L C G+P PT++W G + + T+ Q
Sbjct: 354 PKNLI--LAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQI 411
Query: 518 DSTGTYTCVARNKLGMAKNEVHLEIKD--PTWIVKQPEYAVVQRGSMVSFECKVKHDHTL 575
S Y C N+ G + + D P + + + V + +C
Sbjct: 412 SSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIP 471
Query: 576 SLTVLWLKDNR--ELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 633
+L W K+ + L + L + + +D G YTCVA L L V
Sbjct: 472 TLR--WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV 529
Query: 634 VAPTPTPAPVYDVPNPPFDLELTDQLDK---SVQLSWTPGDDNNSPITKFIIEYEDAMHK 690
PT +Y +P DQ+ + +VQL D + +T ++ ++ ++
Sbjct: 530 KDPTR----IYRMPE--------DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYI 577
Query: 691 PGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNP 750
+ + A+ Y + L + ++ YLT PD+ P
Sbjct: 578 GNRMKKEDDSLTIFGVAERDQGSYTCVA---------STELDQDLAKAYLTVLGRPDR-P 627
Query: 751 TAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKY---- 806
+E ++ +TW P G +N P Y V + + D++ V + SKY
Sbjct: 628 RDLELTDLAERSVRLTWIP--GDANNSPITDYVVQFEE----DQFQPGVWHDHSKYPGSV 681
Query: 807 --IVSGTPTFVPYLIKVQALNDMGFAPE--PAVVMGHSGEDLPMVAPGNVRVNVVNSTLA 862
V +V Y +V A+N++G + P+ SG P PG+V+
Sbjct: 682 NSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAP-PESNPGDVKGEGTRKNNM 740
Query: 863 EVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFS 922
E+ W P+ S G Y I W+ +R R + + G P P
Sbjct: 741 EITWTPMNATSAFGPNLRY-IVKWR-----RRETREAWNNVTVWGSRYVVGQTPVYVP-- 792
Query: 923 HYTLNVRVVNGKGEGPASPDRVFNTPEGVP-SAPSSLKIVNPTLDSLTLEWDP--PSHPN 979
Y + V+ N G+GP + + E P +AP+ +K+ +++L+W+
Sbjct: 793 -YEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQ 851
Query: 980 GILTEYTLKYQPINSTHE----LGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAG 1035
G L EY Y +S + P ++ R + L + YK G
Sbjct: 852 GQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRG 911
Query: 1036 SGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISWEYEGPEHVN 1095
G + + TT + P + + P + + N+ W++ PEH N
Sbjct: 912 DGPRSETKEFTTPEGVPSAPR-----RFRVRQPNLETI---------NLEWDH--PEHPN 955
Query: 1096 -----FYVEYGVAGSKEEWRKEIVNG---SRSFFGLKGLMPGTAYKVRVGA---VGDSGF 1144
+ ++Y VA + + K+IV +++ F ++ P + Y+ + A VG
Sbjct: 956 GIMIGYTLKY-VAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEA 1014
Query: 1145 VSSEDVFETGPAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKE 1204
V+ E A + Q DIATQGWFIGLMCA+ALL+LILLIVCFI+R++GGKYPV+EK+
Sbjct: 1015 VTEESPAPPNEAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVREKK 1074
Query: 1205 DAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNG 1264
D PE KE+DG+F +YSD ED+KPL+ GS+T D T+K+++SDDSLVDYGEG G
Sbjct: 1075 DVPLGPE--DPKEEDGSF-DYSD-EDNKPLQ-GSQTSLDGTIKQQESDDSLVDYGEGGEG 1129
Query: 1265 QFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNS 1302
QFNEDGSFIGQY+ KK+KE EGNESSEA SPVNA+ S
Sbjct: 1130 QFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYS 1167
>gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo
sapiens]
Length = 1248
Score = 918 bits (2373), Expect = 0.0
Identities = 510/1290 (39%), Positives = 733/1290 (56%), Gaps = 70/1290 (5%)
Query: 21 LFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSW 80
L LC +++P E+L++PP IT+QSP+ ++ P ++I ++CEA GKP F W
Sbjct: 11 LLLCSPCLLIQIP------EELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRW 64
Query: 81 TRNGTHFDIDKDPLVTM--KPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIV 138
TR+G HF ++ VT+ P +G+ I + A+ ++G+Y+C A N+ G A+S+ I
Sbjct: 65 TRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIR 124
Query: 139 VRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGL 198
+ +P W KE ++P+ ++ G+S+VLPC PP P I+WM++ + Q ERV+ G
Sbjct: 125 LMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQ 184
Query: 199 NGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFY 258
NG+LYF+NVL D DYIC+A F T+TI QK+PI ++V + + + D
Sbjct: 185 NGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMID------------ 232
Query: 259 GAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVY 318
R P L P ++S+ L+G L LECIAEG PTP I W + G +P +R Y
Sbjct: 233 -------RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTY 285
Query: 319 KNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDG 378
+N KTLQ++ V E D G Y+C+A+N+LG+ H V V+AAPYW+ PQ+ + PGE
Sbjct: 286 QNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETA 345
Query: 379 TLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEY 438
L C+ G P+P ++W NG+P+E D +I +I SNVQ + V QC A N +
Sbjct: 346 RLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRH 405
Query: 439 GYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALH 498
G LLANA++ V+ P +ILT N Y + A L C FG+P+P+++W + L
Sbjct: 406 GLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQ 465
Query: 499 EDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQ 558
++ + + NGTL I Q + TG Y C+A N +L++KD T I + P + +
Sbjct: 466 DERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEK 525
Query: 559 RGSMVSFECKVKHDHTLSLTVLWLKDNR---ELPSDERFTVDKDHLVVADVSDDDSGTYT 615
+GS V+F C+ D +L ++ W D R EL +++ ++ LV+ + D G Y+
Sbjct: 526 KGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYS 585
Query: 616 CVANTTLDSVSASAVLSVV-APTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNN 674
CVA+T LD V + A L VV +P P P V DL L Q V++SW+P +D+N
Sbjct: 586 CVASTELDVVESRAQLLVVGSPGPVPRLVLS------DLHLLTQ--SQVRVSWSPAEDHN 637
Query: 675 SPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSE 734
+PI K+ IE+ED P W+ +V G QT+ LKLSPYV+Y+FRV A+N G PS
Sbjct: 638 APIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSP 697
Query: 735 ASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDE 794
SE +T + P+KNP V+G G+E N+VITWKPL + N P +QY+V WR +
Sbjct: 698 VSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGP 757
Query: 795 WTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRV 854
W +V++ +VS T TFVPY IKVQA+N G PEP V +G+SGED P P +
Sbjct: 758 WQEQIVSD-PFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGI 816
Query: 855 NVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGM 914
++NS+ V W PV L ++GHL+GY + YW+ S K ++RHI K + + T +
Sbjct: 817 EILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVI 876
Query: 915 LPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDP 974
L GL P+S Y L V+ NG+G GPAS + F+TPEGVP P +L + + SL L W P
Sbjct: 877 LSGLRPYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQP 935
Query: 975 PSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSA 1034
P NG+LT Y L Y P++ + +L+ P +T L +L+ RY+F A T
Sbjct: 936 PLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTH-NLTDLSPHLRYRFQLQATTKE 994
Query: 1035 GSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISW-EYEGPEH 1093
G G I E T+ +GI D G N++A A E Y+ +SW EG +
Sbjct: 995 GPGEAIVREG-GTMALSGI--SDFG------------NISATAGENYSVVSWVPKEGQCN 1039
Query: 1094 VNFYVEYGVAGSKE---EWRKEIVNGSRSFFGLKGLMPGTAYKVRVGAVGDSGFVSSEDV 1150
F++ + G ++ + V+ ++S + L P T Y++ + + F V
Sbjct: 1040 FRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTDYEIHL--FKERMFRHQMAV 1097
Query: 1151 FETGPA-MASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHAD 1209
G + AT+GWFIG + A+ LL+L+LLI+CFI+R+KGGKY VK+KED D
Sbjct: 1098 KTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVD 1157
Query: 1210 PEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPS-DRTVKKEDSDDSLVDYGEGVNGQFNE 1268
E +PMK D TFGEYSD E+ GS PS + +K SDDSL DYG V+ QFNE
Sbjct: 1158 SEARPMK--DETFGEYSDNEEK---AFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNE 1212
Query: 1269 DGSFIGQYSGKKEKEPAEGNESSEAPSPVN 1298
DGSFIGQYSGKKEKE A GN+SS A SP+N
Sbjct: 1213 DGSFIGQYSGKKEKEAAGGNDSSGATSPIN 1242
>gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 1253
Score = 913 bits (2360), Expect = 0.0
Identities = 508/1290 (39%), Positives = 733/1290 (56%), Gaps = 65/1290 (5%)
Query: 21 LFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSW 80
L LC +++P + + +++PP IT+QSP+ ++ P ++I ++CEA GKP F W
Sbjct: 11 LLLCSPCLLIQIPEEYEG-HHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRW 69
Query: 81 TRNGTHFDIDKDPLVTM--KPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIV 138
TR+G HF ++ VT+ P +G+ I + A+ ++G+Y+C A N+ G A+S+ I
Sbjct: 70 TRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIR 129
Query: 139 VRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGL 198
+ +P W KE ++P+ ++ G+S+VLPC PP P I+WM++ + Q ERV+ G
Sbjct: 130 LMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQ 189
Query: 199 NGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFY 258
NG+LYF+NVL D DYIC+A F T+TI QK+PI ++V + + + D
Sbjct: 190 NGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMID------------ 237
Query: 259 GAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVY 318
R P L P ++S+ L+G L LECIAEG PTP I W + G +P +R Y
Sbjct: 238 -------RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTY 290
Query: 319 KNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDG 378
+N KTLQ++ V E D G Y+C+A+N+LG+ H V V+AAPYW+ PQ+ + PGE
Sbjct: 291 QNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETA 350
Query: 379 TLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEY 438
L C+ G P+P ++W NG+P+E D +I +I SNVQ + V QC A N +
Sbjct: 351 RLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRH 410
Query: 439 GYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALH 498
G LLANA++ V+ P +ILT N Y + A L C FG+P+P+++W + L
Sbjct: 411 GLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQ 470
Query: 499 EDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQ 558
++ + + NGTL I Q + TG Y C+A N +L++KD T I + P + +
Sbjct: 471 DERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEK 530
Query: 559 RGSMVSFECKVKHDHTLSLTVLWLKDNR---ELPSDERFTVDKDHLVVADVSDDDSGTYT 615
+GS V+F C+ D +L ++ W D R EL +++ ++ LV+ + D G Y+
Sbjct: 531 KGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYS 590
Query: 616 CVANTTLDSVSASAVLSVV-APTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNN 674
CVA+T LD V + A L VV +P P P V DL L Q V++SW+P +D+N
Sbjct: 591 CVASTELDVVESRAQLLVVGSPGPVPRLVLS------DLHLLTQ--SQVRVSWSPAEDHN 642
Query: 675 SPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSE 734
+PI K+ IE+ED P W+ +V G QT+ LKLSPYV+Y+FRV A+N G PS
Sbjct: 643 APIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSP 702
Query: 735 ASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDE 794
SE +T + P+KNP V+G G+E N+VITWKPL + N P +QY+V WR +
Sbjct: 703 VSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGP 762
Query: 795 WTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRV 854
W +V++ +VS T TFVPY IKVQA+N G PEP V +G+SGED P P +
Sbjct: 763 WQEQIVSD-PFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGI 821
Query: 855 NVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGM 914
++NS+ V W PV L ++GHL+GY + YW+ S K ++RHI K + + T +
Sbjct: 822 EILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVI 881
Query: 915 LPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDP 974
L GL P+S Y L V+ NG+G GPAS + F+TPEGVP P +L + + SL L W P
Sbjct: 882 LSGLRPYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQP 940
Query: 975 PSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSA 1034
P NG+LT Y L Y P++ + +L+ P +T L +L+ RY+F A T
Sbjct: 941 PLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTH-NLTDLSPHLRYRFQLQATTKE 999
Query: 1035 GSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISW-EYEGPEH 1093
G G I E T+ +GI D G N++A A E Y+ +SW EG +
Sbjct: 1000 GPGEAIVREG-GTMALSGI--SDFG------------NISATAGENYSVVSWVPKEGQCN 1044
Query: 1094 VNFYVEYGVAGSKE---EWRKEIVNGSRSFFGLKGLMPGTAYKVRVGAVGDSGFVSSEDV 1150
F++ + G ++ + V+ ++S + L P T Y++ + + F V
Sbjct: 1045 FRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTDYEIHL--FKERMFRHQMAV 1102
Query: 1151 FETGPA-MASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHAD 1209
G + AT+GWFIG + A+ LL+L+LLI+CFI+R+KGGKY VK+KED D
Sbjct: 1103 KTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVD 1162
Query: 1210 PEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPS-DRTVKKEDSDDSLVDYGEGVNGQFNE 1268
E +PMK D TFGEYSD E+ GS PS + +K SDDSL DYG V+ QFNE
Sbjct: 1163 SEARPMK--DETFGEYSDNEEK---AFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNE 1217
Query: 1269 DGSFIGQYSGKKEKEPAEGNESSEAPSPVN 1298
DGSFIGQYSGKKEKE A GN+SS A SP+N
Sbjct: 1218 DGSFIGQYSGKKEKEAAGGNDSSGATSPIN 1247
>gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 1257
Score = 912 bits (2356), Expect = 0.0
Identities = 507/1291 (39%), Positives = 733/1291 (56%), Gaps = 63/1291 (4%)
Query: 21 LFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSW 80
L LC +++P + + +++PP IT+QSP+ ++ P ++I ++CEA GKP F W
Sbjct: 11 LLLCSPCLLIQIPEEYEG-HHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRW 69
Query: 81 TRNGTHFDIDKDPLVTM--KPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIV 138
TR+G HF ++ VT+ P +G+ I + A+ ++G+Y+C A N+ G A+S+ I
Sbjct: 70 TRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIR 129
Query: 139 VRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGL 198
+ +P W KE ++P+ ++ G+S+VLPC PP P I+WM++ + Q ERV+ G
Sbjct: 130 LMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQ 189
Query: 199 NGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFY 258
NG+LYF+NVL D DYIC+A F T+TI QK+PI ++V + + + D
Sbjct: 190 NGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMID------------ 237
Query: 259 GAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVY 318
R P L P ++S+ L+G L LECIAEG PTP I W + G +P +R Y
Sbjct: 238 -------RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTY 290
Query: 319 KNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDG 378
+N KTLQ++ V E D G Y+C+A+N+LG+ H V V+AAPYW+ PQ+ + PGE
Sbjct: 291 QNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETA 350
Query: 379 TLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEY 438
L C+ G P+P ++W NG+P+E D +I +I SNVQ + V QC A N +
Sbjct: 351 RLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRH 410
Query: 439 GYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALH 498
G LLANA++ V+ P +ILT N Y + A L C FG+P+P+++W + L
Sbjct: 411 GLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQ 470
Query: 499 EDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQ 558
++ + + NGTL I Q + TG Y C+A N +L++KD T I + P + +
Sbjct: 471 DERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEK 530
Query: 559 RGSMVSFECKVKHDHTLSLTVLWLKDNR---ELPSDERFTVDKDHLVVADVSDDDSGTYT 615
+GS V+F C+ D +L ++ W D R EL +++ ++ LV+ + D G Y+
Sbjct: 531 KGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYS 590
Query: 616 CVANTTLDSVSASAVLSVV-APTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNN 674
CVA+T LD V + A L VV +P P P V DL L Q V++SW+P +D+N
Sbjct: 591 CVASTELDVVESRAQLLVVGSPGPVPRLVLS------DLHLLTQ--SQVRVSWSPAEDHN 642
Query: 675 SPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSE 734
+PI K+ IE+ED P W+ +V G QT+ LKLSPYV+Y+FRV A+N G PS
Sbjct: 643 APIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSP 702
Query: 735 ASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDE 794
SE +T + P+KNP V+G G+E N+VITWKPL + N P +QY+V WR +
Sbjct: 703 VSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGP 762
Query: 795 WTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRV 854
W +V++ +VS T TFVPY IKVQA+N G PEP V +G+SGED P P +
Sbjct: 763 WQEQIVSD-PFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGI 821
Query: 855 NVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGM 914
++NS+ V W PV L ++GHL+GY + YW+ S K ++RHI K + + T +
Sbjct: 822 EILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVI 881
Query: 915 LPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDP 974
L GL P+S Y L V+ NG+G GPAS + F+TPEGVP P +L + + SL L W P
Sbjct: 882 LSGLRPYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQP 940
Query: 975 PSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSA 1034
P NG+LT Y L Y P++ + +L+ P +T L +L+ RY+F A T
Sbjct: 941 PLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTH-NLTDLSPHLRYRFQLQATTKE 999
Query: 1035 GSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISW-EYEGPEH 1093
G G I E T+ +GI D G N++A A E Y+ +SW EG +
Sbjct: 1000 GPGEAIVREG-GTMALSGI--SDFG------------NISATAGENYSVVSWVPKEGQCN 1044
Query: 1094 VNFYVEYGVAGSKE---EWRKEIVNGSRSFFGLKGLMPGTAYKVRVGAVGDSGFVSSEDV 1150
F++ + G ++ + V+ ++S + L P T Y++ + + F V
Sbjct: 1045 FRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTDYEIHL--FKERMFRHQMAV 1102
Query: 1151 FETGPA-MASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHAD 1209
G + AT+GWFIG + A+ LL+L+LLI+CFI+R+KGGKY VK+KED D
Sbjct: 1103 KTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVD 1162
Query: 1210 PEIQPMKEDDGTFGEYSDAE-DHKPLKKGSRTPS-DRTVKKEDSDDSLVDYGEGVNGQFN 1267
E +PMK D TFGEY E D++ GS PS + +K SDDSL DYG V+ QFN
Sbjct: 1163 SEARPMK--DETFGEYRSLESDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFN 1220
Query: 1268 EDGSFIGQYSGKKEKEPAEGNESSEAPSPVN 1298
EDGSFIGQYSGKKEKE A GN+SS A SP+N
Sbjct: 1221 EDGSFIGQYSGKKEKEAAGGNDSSGATSPIN 1251
>gi|27894376 cell adhesion molecule with homology to L1CAM precursor
[Homo sapiens]
Length = 1224
Score = 879 bits (2271), Expect = 0.0
Identities = 514/1305 (39%), Positives = 716/1305 (54%), Gaps = 103/1305 (7%)
Query: 12 LSAGRVPLILFLCQMIS-ALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEA 70
L G + ++FL S A+E+P + Q PTI +QS E I+CEA
Sbjct: 6 LGRGLIVYLMFLLLKFSKAIEIP------SSVQQVPTIIKQSKVQVAFPFDEYFQIECEA 59
Query: 71 KGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERG 130
KG P P+FSWT++G F ++ P + I +EG ++G Y+C A N+ G
Sbjct: 60 KGNPEPTFSWTKDGNPFYFTDHRII---PSNNSGTFRIPNEGHISHFQGKYRCFASNKLG 116
Query: 131 AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQ 190
A+S I P + KEK++P+ ++ G +VLPC PP GLPP I+WM+ + + Q
Sbjct: 117 IAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVLPCNPPKGLPPLHIYWMNIELEHIEQ 176
Query: 191 SERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAA 250
ERV GDLYF+NV +D+R DY C+A F +TI QK P+ + V S+ ND+ ++
Sbjct: 177 DERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRLRTIVQKMPMKLTVNSLKHANDSSSS 236
Query: 251 NLSDTEFYGAKSSRERPPTFLTP---EGNASNKEELRGNVLSLECIAEGLPTPIIYWAKE 307
++ A S ++R P L P G+ S+ L+G +L LEC AEGLPTP + W K
Sbjct: 237 TEIGSK---ANSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKI 293
Query: 308 DGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAP 367
G LPK R +N+ KTL+I +VS D GNY+C A N LG H V V+ P W P
Sbjct: 294 GGDLPKGRETKENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEEPPRWTKKP 353
Query: 368 QNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII-----FSNV 422
Q+ V S G +G L+C A G P+P I W NG P++ P GD + F+N+
Sbjct: 354 QSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPVDNHP------FAGDVVFPREISFTNL 407
Query: 423 QERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSP 482
Q +AVYQC ASN +G +LANA ++V+ P I T Y + A L C FF SP
Sbjct: 408 QPNHTAVYQCEASNVHGTILANANIDVVDVRPLIQTKDGENYATVVGYSAFLHCEFFASP 467
Query: 483 LPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEI 542
+ W K + L Y ++ENGTL+I ++ G+Y+C N +G +L+I
Sbjct: 468 EAVVSWQKVEEVKPLEGRRYHIYENGTLQINRTTEEDAGSYSCWVENAIGKTAVTANLDI 527
Query: 543 KDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTL--SLTVLWLKDNRELP----SDERFTV 596
++ T + P+ + + M+ C+ K D L SL + W KD D R +
Sbjct: 528 RNATKLRVSPKNPRIPKLHMLELHCESKCDSHLKHSLKLSWSKDGEAFEINGTEDGRIII 587
Query: 597 DKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELT 656
D +L +++V+ +D G Y C A+T LDS A T V DVP+PP +L L+
Sbjct: 588 DGANLTISNVTLEDQGIYCCSAHTALDS----------AADITQVTVLDVPDPPENLHLS 637
Query: 657 DQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVN 716
++ ++SV+L+W G D+NS I+++I+E+E +PG W T V G +TT L L+P+V
Sbjct: 638 ERQNRSVRLTWEAGADHNSNISEYIVEFEGNKEEPGRWEELTRVQGKKTTVILPLAPFVR 697
Query: 717 YSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESN 776
Y FRV+AVN +G+S PS+ S+ + T + PD+NP + S+P ++I W+PL E N
Sbjct: 698 YQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKWEPLKSMEQN 757
Query: 777 GPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVV 836
GPGL+Y+V+W+ + EW V N + +++ + PY +KVQA+N +G P+P V
Sbjct: 758 GPGLEYRVTWKPQGAPVEWEEETVTNHTLRVMTPA-VYAPYDVKVQAINQLGSGPDPQSV 816
Query: 837 MGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNR 896
+SGED P AP V+V+NSTL +V W VP + G L+GY+I +WKT+S
Sbjct: 817 TLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTVPKDRVHGRLKGYQINWWKTKSLLDGRT 876
Query: 897 RHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPS 956
E IL F G + GM+P L+ FS + L V N KG GP S +F TPEGVP P+
Sbjct: 877 HPKEVNILRFSGQRNSGMVPSLDAFSEFHLTVLAYNSKGAGPESEPYIFQTPEGVPEQPT 936
Query: 957 SLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPA-NKTRWTL 1015
LK++ D+ TL W P NG LT Y L+YQ IN T+E+G L D+ I +K W L
Sbjct: 937 FLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYEIGELNDINITTPSKPSWHL 996
Query: 1016 KNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTA 1075
NLN +T+YKFY A TS G G ITEE+ +T+ E G GK+ VN
Sbjct: 997 SNLNATTKYKFYLRACTSQGCGKPITEES-STLGEG-----SKGIGKISGVN-------- 1042
Query: 1076 AAAETYANISWEYEGPEHVNFYVEYGVAGSKEEWRKEIVNGSRSFFGLKGLMPGTAYKVR 1135
+T+ +E G EH+ V + W
Sbjct: 1043 LTQKTHPIEVFE-PGAEHI-------VRLMTKNW-------------------------- 1068
Query: 1136 VGAVGDSGFVSSEDVFET-GPAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNK 1194
GD+ + +DV ET G A DI+TQGWFIGLMCA+ALL L+LL VCF++RN+
Sbjct: 1069 ----GDNDSI-FQDVIETRGREYAGLYDDISTQGWFIGLMCAIALLTLLLLTVCFVKRNR 1123
Query: 1195 GGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDS 1254
GGKY VKEKED H DPEIQ +K D TFGEYSD+ D KPL KGS +R ++ +S DS
Sbjct: 1124 GGKYSVKEKEDLHPDPEIQSVK--DETFGEYSDS-DEKPL-KGSLRSLNRDMQPTESADS 1179
Query: 1255 LVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNA 1299
LV+YGEG +G F+EDGSFIG Y+G KEK E N SS A P+ A
Sbjct: 1180 LVEYGEGDHGLFSEDGSFIGAYAGSKEKGSVESNGSSTATFPLRA 1224
>gi|237858680 neurofascin isoform 5 precursor [Homo sapiens]
Length = 619
Score = 672 bits (1734), Expect = 0.0
Identities = 326/619 (52%), Positives = 429/619 (69%), Gaps = 19/619 (3%)
Query: 20 ILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFS 79
+L L + A+E+P+DP + +L QPPTIT+QS KD+I+DPR+NI+I+CEAKG P PSF
Sbjct: 15 LLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFH 74
Query: 80 WTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 139
WTRN F+I KDP V+M+ +GTL+I+ S G+ E YEG YQC ARN+ G A+SN I +
Sbjct: 75 WTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRL 134
Query: 140 RPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLN 199
+ S+SPLW KE L+P+ +Q G L L C PP GLP P+IFWM +S + + Q +RVSQG N
Sbjct: 135 QVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHN 194
Query: 200 GDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYG 259
GDLYFSNV+ +D + DY C ARF+ T TIQQK P ++KV++
Sbjct: 195 GDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTT------------------ 236
Query: 260 AKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK 319
+ ER P+F+ P+G AS++ LRG L LECIA G+PTP I W K+ G LP ++ ++
Sbjct: 237 -RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFE 295
Query: 320 NFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT 379
NF K L+I +VSE DSG Y C+A N +G+I HTISVRVKAAPYW+ P+NL+L+PGEDG
Sbjct: 296 NFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGR 355
Query: 380 LICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYG 439
L+CRANGNPKP + W+ NG P++ AP +P+R++ GDTIIF + Q S AVYQCN SNE+G
Sbjct: 356 LVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 415
Query: 440 YLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE 499
YLLANAFV+VL PPR+L+P N L +VI LDC FFGSP+PT+ WFK +GS L
Sbjct: 416 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG 475
Query: 500 DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 559
Y ++ENG+LEI + +K+ G YTCVA N LG A+N+V LE+KDPT I + PE V +R
Sbjct: 476 GNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARR 535
Query: 560 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVAN 619
G+ V EC+VKHD +L LTV WLKD+ L R + D L + V++ D G+YTCVA+
Sbjct: 536 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVAS 595
Query: 620 TTLDSVSASAVLSVVAPTP 638
T LD A A L+V+ P
Sbjct: 596 TELDQDLAKAYLTVLGNCP 614
>gi|237858682 neurofascin isoform 6 precursor [Homo sapiens]
Length = 613
Score = 662 bits (1708), Expect = 0.0
Identities = 325/619 (52%), Positives = 426/619 (68%), Gaps = 25/619 (4%)
Query: 20 ILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFS 79
+L L + A+E+P+D L QPPTIT+QS KD+I+DPR+NI+I+CEAKG P PSF
Sbjct: 15 LLCLLSLGGAIEIPMD------LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFH 68
Query: 80 WTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 139
WTRN F+I KDP V+M+ +GTL+I+ S G+ E YEG YQC ARN+ G A+SN I +
Sbjct: 69 WTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRL 128
Query: 140 RPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLN 199
+ S+SPLW KE L+P+ +Q G L L C PP GLP P+IFWM +S + + Q +RVSQG N
Sbjct: 129 QVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHN 188
Query: 200 GDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYG 259
GDLYFSNV+ +D + DY C ARF+ T TIQQK P ++KV++
Sbjct: 189 GDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTT------------------ 230
Query: 260 AKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK 319
+ ER P+F+ P+G AS++ LRG L LECIA G+PTP I W K+ G LP ++ ++
Sbjct: 231 -RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFE 289
Query: 320 NFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT 379
NF K L+I +VSE DSG Y C+A N +G+I HTISVRVKAAPYW+ P+NL+L+PGEDG
Sbjct: 290 NFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGR 349
Query: 380 LICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYG 439
L+CRANGNPKP + W+ NG P++ AP +P+R++ GDTIIF + Q S AVYQCN SNE+G
Sbjct: 350 LVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 409
Query: 440 YLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE 499
YLLANAFV+VL PPR+L+P N L +VI LDC FFGSP+PT+ WFK +GS L
Sbjct: 410 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG 469
Query: 500 DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 559
Y ++ENG+LEI + +K+ G YTCVA N LG A+N+V LE+KDPT I + PE V +R
Sbjct: 470 GNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARR 529
Query: 560 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVAN 619
G+ V EC+VKHD +L LTV WLKD+ L R + D L + V++ D G+YTCVA+
Sbjct: 530 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVAS 589
Query: 620 TTLDSVSASAVLSVVAPTP 638
T LD A A L+V+ P
Sbjct: 590 TELDQDLAKAYLTVLGNCP 608
>gi|4827022 contactin 2 precursor [Homo sapiens]
Length = 1040
Score = 372 bits (954), Expect = e-102
Identities = 285/951 (29%), Positives = 426/951 (44%), Gaps = 75/951 (7%)
Query: 62 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 121
E +++ C A+ PP ++ W NGT ++ + G + IM+ KA+ GVY
Sbjct: 55 EQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGN----LVIMNPTKAQD-AGVY 109
Query: 122 QCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWM 181
QC A N G VS ++R ++KE+ +P+ G ++LPC PP P W+
Sbjct: 110 QCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWL 169
Query: 182 DNSFQR-LPQSER--VSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKV 238
N F +P R VSQ G+LY + D +Y C A + S K
Sbjct: 170 LNEFPNFIPTDGRHFVSQ-TTGNLYIARTNASDLG-NYSCLATSH--------MDFSTKS 219
Query: 239 ISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLP 298
+ +AA DT + A S + R P + L G ++LEC A G P
Sbjct: 220 VFSKFAQLNLAAE--DTRLF-APSIKARFP---------AETYALVGQQVTLECFAFGNP 267
Query: 299 TPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVK 358
P I W K DG L T E TLQI VS D G Y+C A+N+ G + V+
Sbjct: 268 VPRIKWRKVDGSLSPQWTTA---EPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQ 324
Query: 359 AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII 418
A P W+ + G + C A G P+P + WL NG P+ A + + GD +
Sbjct: 325 AQPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPL--ASQNRVEVLAGD-LR 381
Query: 419 FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI-LTPANTLYQVIANRPALLDCA 477
FS + S +YQC A N++G + A+A + V A P L P L L+ C
Sbjct: 382 FSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQ 441
Query: 478 FFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNE 537
+P + W KG + ++ + +GTL I + G YTC A N +G A +
Sbjct: 442 PRAAPKAVVLWSKGTE-ILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANST 500
Query: 538 VHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDE----- 592
L ++D T I P A + G ++ +C HD T+ LT W D+ + D+
Sbjct: 501 GILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHY 560
Query: 593 RFTVDKD---HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNP 649
R T K+ L + + G YTC+A T +DS S A + V P P P
Sbjct: 561 RRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGP----------PGP 610
Query: 650 PFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWH----HQTEVSGTQT 705
P + + D D ++QLSW+ G DN+SPI K+ ++ G W + + G
Sbjct: 611 PGGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTP--PAGKWKQVRTNPANIEGNAE 668
Query: 706 TAQ-LKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLV 764
TAQ L L+P+++Y FRV+A N +G PS S + T+ + P P+ + G G P L+
Sbjct: 669 TAQVLGLTPWMDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELI 728
Query: 765 ITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPT---FVPYLIKV 821
+ W P++ NG G Y +S+R++ T+ V ++Y V + + P+ +K+
Sbjct: 729 VNWTPMSREYQNGDGFGYLLSFRRQGSTHWQTARVPGADAQYFVYSNESVRPYTPFEVKI 788
Query: 822 QALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGY 881
++ N G PE + +S E+ P VAP V V+S+ V W+PV + + G L GY
Sbjct: 789 RSYNRRGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQ-QDMNGILLGY 847
Query: 882 RIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASP 941
I YWK R + G T + GL P + Y + VR N G GPASP
Sbjct: 848 EIRYWKAGDKEAAADR------VRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTGPASP 901
Query: 942 DRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDP--PSHPNGILTEYTLKYQ 990
T + P P + SL+++WDP P +T Y + YQ
Sbjct: 902 SANATTMKPPPRRPPGNISWTFSSSSLSIKWDPVVPFRNESAVTGYKMLYQ 952
Score = 89.7 bits (221), Expect = 2e-17
Identities = 104/419 (24%), Positives = 163/419 (38%), Gaps = 60/419 (14%)
Query: 46 PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLI 105
P+I + P + + + ++C A G P P W + +D ++ P T
Sbjct: 239 PSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWRK------VDG----SLSPQWTTAE 288
Query: 106 INIMSEGKAETYEGVYQCTARNERGA-AVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLV 164
+ + EG Y+C A N +G V I+V+ P W K + G +L
Sbjct: 289 PTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQ--AQPEWLK-VISDTEADIGSNLR 345
Query: 165 LPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNH 224
C G P P + W+ N + L RV + L GDL FS + ED+ Y C A H
Sbjct: 346 WGC-AAAGKPRPTVRWLRNG-EPLASQNRV-EVLAGDLRFSKLSLEDSGM-YQCVAENKH 401
Query: 225 TQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELR 284
TI ++V+ ++ D R P L P R
Sbjct: 402 -GTIYASAELAVQALAPD--------------------FRLNPVRRLIPAA--------R 432
Query: 285 GNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKN 344
G + + C P ++ W+K +L + V + TL I ++S +D G Y C A+N
Sbjct: 433 GGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAEN 492
Query: 345 ALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRI--SWLTNGVPIE 402
+G + T + V+ A AP + ++ G++ TL C A+ +P + +W + PI+
Sbjct: 493 FMGKANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPID 552
Query: 403 IAPDDPS--------RKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP 453
D P ++ GD I N Q R Y C A A V V P
Sbjct: 553 F--DKPGGHYRRTNVKETIGDLTIL-NAQLRHGGKYTCMAQTVVDSASKEATVLVRGPP 608
Score = 58.9 bits (141), Expect = 3e-08
Identities = 84/373 (22%), Positives = 137/373 (36%), Gaps = 78/373 (20%)
Query: 41 DLVQPPTITQQSPK------DYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPL 94
D VQ I Q P+ D D N+ C A GKP P+ W RNG +PL
Sbjct: 315 DTVQGRIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNG-------EPL 367
Query: 95 VTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEP 154
+ L ++ + G+YQC A N+ G ++ + + +P + +L P
Sbjct: 368 ASQN-RVEVLAGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDF---RLNP 423
Query: 155 ----ITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPE 210
I G +++PC+P P ++ W + + L S RV+ +G L N+
Sbjct: 424 VRRLIPAARGGEILIPCQPR-AAPKAVVLWSKGT-EILVNSSRVTVTPDGTLIIRNISRS 481
Query: 211 DTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTF 270
D + Y C+A N +SV+ D T+A + +D
Sbjct: 482 DEGK-YTCFAE-NFMGKANSTGILSVR----DATKITLAPSSADINL------------- 522
Query: 271 LTPEGNASNKEELRGNVLSLECIAEGLPTP--IIYWAKEDGMLP-------KNRTVYKNF 321
G+ L+L+C A PT W +D + RT K
Sbjct: 523 --------------GDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKET 568
Query: 322 EKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLI 381
L I++ G Y C+A+ + + +V V+ PG G ++
Sbjct: 569 IGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRG-------------PPGPPGGVV 615
Query: 382 CRANGNPKPRISW 394
R G+ ++SW
Sbjct: 616 VRDIGDTTIQLSW 628
Score = 56.6 bits (135), Expect = 2e-07
Identities = 61/271 (22%), Positives = 105/271 (38%), Gaps = 33/271 (12%)
Query: 373 SPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQC 432
S E L CRA +P W NG +++ P + + G+ +I + + + + VYQC
Sbjct: 52 STEEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLVIMNPTKAQDAGVYQC 111
Query: 433 NASNEYGYLLAN------AFVNVLAEPPRILTPANTLYQVI--ANRPALLDCAFFGSPLP 484
ASN G +++ F+ ++ R A+ + V+ N PA P
Sbjct: 112 LASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPA-------HYPGL 164
Query: 485 TIEWFKGAKGSALHED--IYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEV---- 538
+ W + + D +V G L I G Y+C+A + + + V
Sbjct: 165 SYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKF 224
Query: 539 ---HLEIKD-----PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPS 590
+L +D P+ + P G V+ EC + + W K + L
Sbjct: 225 AQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPV--PRIKWRKVDGSL-- 280
Query: 591 DERFTVDKDHLVVADVSDDDSGTYTCVANTT 621
++T + L + VS +D GTY C A +
Sbjct: 281 SPQWTTAEPTLQIPSVSFEDEGTYECEAENS 311
>gi|75709184 contactin 3 [Homo sapiens]
Length = 1028
Score = 365 bits (936), Expect = e-100
Identities = 276/935 (29%), Positives = 413/935 (44%), Gaps = 77/935 (8%)
Query: 62 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 121
+ I + CEA+G P P + W NG+ DID K G L++ I +T G Y
Sbjct: 44 KKITLHCEARGNPSPHYRWQLNGS--DIDMSMEHRYKLNGGNLVV-INPNRNWDT--GTY 98
Query: 122 QCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWM 181
QC A N G VS ++ + + + ++++ GQ +VL C PP W+
Sbjct: 99 QCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWI 158
Query: 182 DNSFQRLPQ--SERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVI 239
N + + S R G LY S V P D +Y C T P + +
Sbjct: 159 FNEYPSFVEEDSRRFVSQETGHLYISKVEPSDV-GNYTCVVTSMVTNARVLGSPTPLVLR 217
Query: 240 SVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPT 299
S + + Y K + P T +G+ + LEC A G P
Sbjct: 218 SDGVMGE-----------YEPKIEVQFPETL----------PAAKGSTVKLECFALGNPI 256
Query: 300 PIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKA 359
P I W + DG+ ++ + F L+I + + D+G+Y+CIA+N+ G + A
Sbjct: 257 PQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYA 316
Query: 360 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIF 419
P+W+ +++ ++ + CRA+G PKP WL NG + + + +I+ +
Sbjct: 317 KPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVL---EERTQIENGALTI 373
Query: 420 SNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI-LTPANTLYQVIANRPALLDCAF 478
SN+ S ++QC A N++G + ++A + V+A P P L QV LDC
Sbjct: 374 SNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKP 433
Query: 479 FGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEV 538
SP W KG HE I +L++ G L+I K GTYTC+A N+ G A
Sbjct: 434 RASPRALSSWKKGDVSVQEHERISLLNDGG-LKIANVTKADAGTYTCMAENQFGKANGTT 492
Query: 539 HLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW-----LKDNRELPS--D 591
HL + +PT I P V G V C+V+HD L + W L D ++ S +
Sbjct: 493 HLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFE 552
Query: 592 ERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPF 651
+ L++ ++ SG Y C+ T +DSVS++A L V P PP
Sbjct: 553 KVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGS----------PGPPE 602
Query: 652 DLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEV-----SGTQTT 706
++++ + D + QLSW G DN+SP+ + I+ W T V T T
Sbjct: 603 NVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVG--WQTVTTVPEVIDGKTHTA 660
Query: 707 AQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVIT 766
++L+P+V Y FRV+A N IG PS SE+ T+ + P+ P+ V G G LVIT
Sbjct: 661 TVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVIT 720
Query: 767 WKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVA--NVSKYIV--SGTPTFVPYLIKVQ 822
W P+ NG G Y V++R G W VV + +Y+ + PY +KV
Sbjct: 721 WDPVPEELQNGEGFGYVVAFRPL-GVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVG 779
Query: 823 ALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYR 882
N+ G P V S E+ P VAP V N ++S+ EV W+ +P K GHL GY
Sbjct: 780 VYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYE 839
Query: 883 IYYW----KTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGP 938
+ YW K +SSSK + G++T L GL+ Y VR N G GP
Sbjct: 840 VRYWNGGGKEESSSK----------MKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGP 889
Query: 939 ASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD 973
S T + PS P + N T + L W+
Sbjct: 890 FSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWE 924
Score = 147 bits (372), Expect = 5e-35
Identities = 190/814 (23%), Positives = 322/814 (39%), Gaps = 121/814 (14%)
Query: 325 LQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAP-----------------YWITAP 367
L I V +D GNY C+ + + + RV +P + P
Sbjct: 181 LYISKVEPSDVGNYTCVVTSMV------TNARVLGSPTPLVLRSDGVMGEYEPKIEVQFP 234
Query: 368 QNLVLSPGEDGTLICRANGNPKPRISWL-TNGVPIEIAPDDPSRKIDGDTIIFSNVQERS 426
+ L + G L C A GNP P+I+W ++G+P + RK G + N Q+
Sbjct: 235 ETLPAAKGSTVKLECFALGNPIPQINWRRSDGLPF--SSKIKLRKFSG-VLEIPNFQQED 291
Query: 427 SAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTI 486
+ Y+C A N G +A + A+P + + ++ +C G P P+
Sbjct: 292 AGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDV--EIAVEDSLYWECRASGKPKPSY 349
Query: 487 EWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPT 546
W K L E + ENG L I +G + C+A NK G+ + L++
Sbjct: 350 RWLKNGAALVLEERTQI--ENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKV---- 403
Query: 547 WIVKQPEYAV--------VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDK 598
+ P+++ VQ GS+VS +CK + + W K + + ER ++
Sbjct: 404 -VASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSS--WKKGDVSVQEHERISLLN 460
Query: 599 DH-LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTD 657
D L +A+V+ D+GTYTC+A + + L V PT + P +++++
Sbjct: 461 DGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTR-------ITLAPSNMDVS- 512
Query: 658 QLDKSVQLSWTPGDDNNSPITKFIIE--YEDAM---HKPGLWHHQTEVSGTQTTAQLKLS 712
+ +SV L P + P+ I + A+ K G H +V G+ + + +
Sbjct: 513 -VGESVIL---PCQVQHDPLLDIIFTWYFNGALADFKKDG--SHFEKVGGSSSGDLMIRN 566
Query: 713 PYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNG 772
+ +S + + + G S A++ + + P +N E + ++WK G
Sbjct: 567 IQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQ---LSWK--EG 621
Query: 773 FESNGPGLQYKVSWRQKDGDDEWTSVVVANV------SKYIVSGTPTFVPYLIKVQALND 826
+++ P + Y + R T V V + +V P +V Y +V A N
Sbjct: 622 KDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELNP-WVEYEFRVVASNK 680
Query: 827 MGFAPEPAVVMG--HSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIY 884
+G EP++ + E +P V P V + + + WDPVP + G GY +
Sbjct: 681 IG-GGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVA 739
Query: 885 Y-------W-KTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGE 936
+ W +T +S R++ + + P+S Y + V V N KGE
Sbjct: 740 FRPLGVTTWIQTVVTSPDTPRYVFRN-------------ESIVPYSPYEVKVGVYNNKGE 786
Query: 937 GPASP-DRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD--PPSHPNGILTEYTLKYQPIN 993
GP SP VF+ E APS + + + + + W+ P NG L Y ++Y
Sbjct: 787 GPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGG 846
Query: 994 STHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGI 1053
E +K+ N+T L+ L + Y A SAG+G VTT
Sbjct: 847 GKEESSS--KMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPS 904
Query: 1054 LPPDVGAGKVQAVNPRISNLTAAAAETYANISWE 1087
PP N+ A +T ++WE
Sbjct: 905 QPP--------------GNVVWNATDTKVLLNWE 924
Score = 116 bits (291), Expect = 1e-25
Identities = 211/934 (22%), Positives = 349/934 (37%), Gaps = 131/934 (14%)
Query: 268 PTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYW---AKEDGMLPKNRTVYKNFEKT 324
P F+ N+ ++L C A G P+P W + M ++R YK
Sbjct: 26 PVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDIDMSMEHR--YKLNGGN 83
Query: 325 LQIIHVSEA-DSGNYQCIAKNALGAI-HHTISVRVKAAPYWITAPQNLV-LSPGEDGTLI 381
L +I+ + D+G YQC A N+LG I ++ + T ++ V + G+ L+
Sbjct: 84 LVVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLL 143
Query: 382 CRANGNPKPR-----ISWLTNGVPIEIAPDDPSRKIDGDT--IIFSNVQERSSAVYQCNA 434
C P P +W+ N P +D R + +T + S V+ Y C
Sbjct: 144 C----GPPPHSGELSYAWIFNEYP-SFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVV 198
Query: 435 SNEYGYLLANAFV------------NVLAE-PPRILTPANTLYQVIANRPALLDCAFFGS 481
++ ++ NA V V+ E P+I L+C G+
Sbjct: 199 TS----MVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGN 254
Query: 482 PLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLG--MAKNEVH 539
P+P I W + + G I + +G LEIP Q++ G+Y C+A N G +A+ +
Sbjct: 255 PIPQINW-RRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLT 313
Query: 540 LEIKDPTWI--VKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVD 597
K P W+ +K E AV + +EC+ S WLK+ L +ER ++
Sbjct: 314 YYAK-PHWVQLIKDVEIAV---EDSLYWECRASGKPKPSYR--WLKNGAALVLEERTQIE 367
Query: 598 KDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTD 657
L ++++S DSG + C+A V +SA L VVA P D P +
Sbjct: 368 NGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAP------DFSKNPMKKLVQV 421
Query: 658 QLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNY 717
Q+ V L P SP + K + + E LK++
Sbjct: 422 QVGSLVSLDCKP---RASP------RALSSWKKGDVSVQEHERISLLNDGGLKIANVTKA 472
Query: 718 ---SFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPD------------N 762
++ MA N GK+ + + +T+ + P+ ++ E +
Sbjct: 473 DAGTYTCMAENQFGKA--NGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLD 530
Query: 763 LVITW---KPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLI 819
++ TW L F+ +G S +K G +++ N+ + SG Y+
Sbjct: 531 IIFTWYFNGALADFKKDG-------SHFEKVGGSSSGDLMIRNI-QLKHSG-----KYVC 577
Query: 820 KVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQ 879
VQ D + +V G G P NV+V+ + T A++ W K +
Sbjct: 578 MVQTGVDSVSSAADLIVRGSPG------PPENVKVDEITDTTAQLSWKEG--KDNHSPVI 629
Query: 880 GYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTH-GMLPGLEPFSHYTLNVRVVNGKGEG- 937
Y I S + + + I KTH + L P+ Y V N G G
Sbjct: 630 SYSIQARTPFSVGWQTVTTVPEVI----DGKTHTATVVELNPWVEYEFRVVASNKIGGGE 685
Query: 938 PASPDRVFNTPEGVPSA-PSSLKIVNPTLDSLTLEWDPPSH--PNGILTEYTLKYQPINS 994
P+ P T E VP PS + + L + WDP NG Y + ++P+
Sbjct: 686 PSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGV 745
Query: 995 THELGPLVDLKIPANKTRWTLKNLNF----STRYKFYFYAQTSAGSGSQITEEAVTTVDE 1050
T + +V + R+ +N + K Y G S +T + +E
Sbjct: 746 TTWIQTVV---TSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVT-TVFSAEEE 801
Query: 1051 AGILPPDVGAGKVQAVNPRISNLTAAAAETYANISWEYEGPEHVNFYVEYGVAGSKEEWR 1110
+ P V A + + +S + I W+ + + V Y G KEE
Sbjct: 802 PTVAPSQVSANSLSSSEIEVS---------WNTIPWKLSNGHLLGYEVRYWNGGGKEESS 852
Query: 1111 KEI-VNGSRSFFGLKGLMPGTAYKVRVGAVGDSG 1143
++ V G+ + L+GL AY V A +G
Sbjct: 853 SKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAG 886
Score = 83.6 bits (205), Expect = 1e-15
Identities = 94/393 (23%), Positives = 158/393 (40%), Gaps = 48/393 (12%)
Query: 46 PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLI 105
P I Q P+ + ++C A G P P +W R+ + + ++ +G L
Sbjct: 227 PKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSD---GLPFSSKIKLRKFSGVLE 283
Query: 106 INIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVL 165
I + A G Y+C A N RG V+ + ++ P W + ++ + + SL
Sbjct: 284 IPNFQQEDA----GSYECIAENSRGKNVARGRLTYYAK-PHWV-QLIKDVEIAVEDSLYW 337
Query: 166 PCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHT 225
CR G P P W+ N L ER +Q NG L SN+ D+ + C A H
Sbjct: 338 ECRAS-GKPKPSYRWLKNG-AALVLEER-TQIENGALTISNLSVTDSGM-FQCIAENKHG 393
Query: 226 QTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRG 285
+ +KV++ A + P L + G
Sbjct: 394 LVYSSAE---LKVVA------------------SAPDFSKNPMKKLV--------QVQVG 424
Query: 286 NVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNA 345
+++SL+C P + W K D + ++ + + L+I +V++AD+G Y C+A+N
Sbjct: 425 SLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQ 484
Query: 346 LGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRI--SWLTNGVPIEI 403
G + T + V AP N+ +S GE L C+ +P I +W NG +
Sbjct: 485 FGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADF 544
Query: 404 APDDPS-RKIDGDT---IIFSNVQERSSAVYQC 432
D K+ G + ++ N+Q + S Y C
Sbjct: 545 KKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVC 577
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 358 bits (919), Expect = 2e-98
Identities = 276/964 (28%), Positives = 428/964 (44%), Gaps = 86/964 (8%)
Query: 39 LEDLVQPPTITQQSPKDYII---DPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLV 95
L + V + Q P D I + + + CE +G P PS+ W RNGT D++ D
Sbjct: 17 LSESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRY 76
Query: 96 TMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPI 155
++ GT II+ SE K G YQC A N G+ +S ++ + ++ +
Sbjct: 77 SLIDGT--FIISNPSEAKDS---GHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAV 131
Query: 156 TLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRL--PQSERVSQGLNGDLYFSNVLPEDTR 213
+++ GQ +VL C PP P I W+ N F S R G+LY S V D
Sbjct: 132 SVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVG 191
Query: 214 EDYICYAR--FNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFL 271
YIC + + + + P++++ ND + Y K P T
Sbjct: 192 S-YICLVKNTVTNARVLSPPTPLTLR-------NDGVMGE------YEPKIEVHFPFTVT 237
Query: 272 TPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVS 331
+G + +EC A G P P I W K +G +P + K+ + L+I +V
Sbjct: 238 AA----------KGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKS-QAVLEIPNVQ 286
Query: 332 EADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPR 391
D+G Y+C A+N+ G ++V P+W+ + L G C+A G P+P
Sbjct: 287 LDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPT 346
Query: 392 ISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLA 451
WL NGVP+ +P ++G ++ NV + + +YQC A N+YG + A+A + +LA
Sbjct: 347 YRWLKNGVPL--SPQSRVEMVNG-VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILA 403
Query: 452 EPPRI-LTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTL 510
P L V ++ +++C GSP PTI W KG + ++ I +L + G+L
Sbjct: 404 SAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPD-GSL 462
Query: 511 EIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVK 570
I A K G Y C N G A+ L +K+PT I P+ + G + CK
Sbjct: 463 RILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNCKAI 522
Query: 571 HDHTLSLTVLWLKDNRELPSDE--------RFTVDKDHLVVADVSDDDSGTYTCVANTTL 622
HD +L +T W + + +E R L++ ++ +G Y C TT
Sbjct: 523 HDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTA 582
Query: 623 DSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFII 682
DSVS A L V P P PP + + + + + LSW+P DN+SPI+ + +
Sbjct: 583 DSVSDEAELLVRGP----------PGPPGIVIVEEITESTATLSWSPAADNHSPISSYNL 632
Query: 683 EYEDAMHKPGLWHHQTE------VSGTQTTAQ-LKLSPYVNYSFRVMAVNSIGKSLPSEA 735
+ P QT ++G +A + L+P+V Y FRV+A N IG PS
Sbjct: 633 Q----ARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTP 688
Query: 736 SEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEW 795
S T + P PT V G LVI W+P++ NG G Y V++R +G W
Sbjct: 689 SRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFR-PNGTRGW 747
Query: 796 TSVVV--ANVSKYIV--SGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGN 851
+V + SK+I P P+ +KV N+ G P +V+ S E P AP +
Sbjct: 748 KEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTD 807
Query: 852 VRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKT 911
V+ V+ + V W + K G QG+ + YWK + + +G+++
Sbjct: 808 VKATSVSVSEILVAWKHI--KESLGRPQGFEVGYWKDMEQED------TAETVKTRGNES 859
Query: 912 HGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPS-APSSLKIVNPTLDSLTL 970
+L GLE + Y VR NG G GP S + T + PS APS+L+ ++L
Sbjct: 860 FVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRWEQQG-SQVSL 918
Query: 971 EWDP 974
W+P
Sbjct: 919 GWEP 922
Score = 40.8 bits (94), Expect = 0.009
Identities = 42/198 (21%), Positives = 80/198 (40%), Gaps = 12/198 (6%)
Query: 950 GVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQ-PINSTHELGPLVDLKIPA 1008
G P P + + T + TL W P + + ++ Y L+ + P + + V I
Sbjct: 595 GPPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITG 654
Query: 1009 NKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNP 1068
+ +LN Y+F A G+G T + +EA P V +
Sbjct: 655 DMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEA---VPKTAPTNVSGRSG 711
Query: 1069 RISNLTAAAAETYANISWEYEGPEHVNFYVEYGVAGSKEEWRKEIVNGSRS---FFGLKG 1125
R L A + +S E++ E + V + G++ W++++V S + + +
Sbjct: 712 RRHELVIA----WEPVSEEFQNGEGFGYIVAFRPNGTR-GWKEKMVTSSEASKFIYRDES 766
Query: 1126 LMPGTAYKVRVGAVGDSG 1143
+ P T ++V+VG + G
Sbjct: 767 VPPLTPFEVKVGVYNNKG 784
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 358 bits (918), Expect = 2e-98
Identities = 274/952 (28%), Positives = 424/952 (44%), Gaps = 86/952 (9%)
Query: 51 QSPKDYII---DPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIIN 107
Q P D I + + + CE +G P PS+ W RNGT D++ D ++ GT II+
Sbjct: 103 QEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGT--FIIS 160
Query: 108 IMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPC 167
SE K G YQC A N G+ +S ++ + ++ ++++ GQ +VL C
Sbjct: 161 NPSEAKDS---GHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMC 217
Query: 168 RPPIGLPPPIIFWMDNSFQRL--PQSERVSQGLNGDLYFSNVLPEDTREDYICYAR--FN 223
PP P I W+ N F S R G+LY S V D YIC +
Sbjct: 218 SPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGS-YICLVKNTVT 276
Query: 224 HTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEEL 283
+ + + P++++ ND + Y K P T
Sbjct: 277 NARVLSPPTPLTLR-------NDGVMGE------YEPKIEVHFPFTVTAA---------- 313
Query: 284 RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAK 343
+G + +EC A G P P I W K +G +P + K+ + L+I +V D+G Y+C A+
Sbjct: 314 KGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKS-QAVLEIPNVQLDDAGIYECRAE 372
Query: 344 NALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEI 403
N+ G ++V P+W+ + L G C+A G P+P WL NGVP+
Sbjct: 373 NSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPL-- 430
Query: 404 APDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI-LTPANT 462
+P ++G ++ NV + + +YQC A N+YG + A+A + +LA P L
Sbjct: 431 SPQSRVEMVNG-VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKK 489
Query: 463 LYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGT 522
V ++ +++C GSP PTI W KG + ++ I +L + G+L I A K G
Sbjct: 490 TIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPD-GSLRILNASKSDEGK 548
Query: 523 YTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWL 582
Y C N G A+ L +K+PT I P+ + G + CK HD +L +T W
Sbjct: 549 YVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWT 608
Query: 583 KDNRELPSDE--------RFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVV 634
+ + +E R L++ ++ +G Y C TT DSVS A L V
Sbjct: 609 LKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVR 668
Query: 635 APTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLW 694
P P PP + + + + + LSW+P DN+SPI+ + ++ P
Sbjct: 669 GP----------PGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQ----ARSPFSL 714
Query: 695 HHQTE------VSGTQTTAQ-LKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPD 747
QT ++G +A + L+P+V Y FRV+A N IG PS S T + P
Sbjct: 715 GWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPK 774
Query: 748 KNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVV--ANVSK 805
PT V G LVI W+P++ NG G Y V++R +G W +V + SK
Sbjct: 775 TAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFR-PNGTRGWKEKMVTSSEASK 833
Query: 806 YIV--SGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAE 863
+I P P+ +KV N+ G P +V+ S E P AP +V+ V+ +
Sbjct: 834 FIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEIL 893
Query: 864 VHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSH 923
V W + K G QG+ + YWK + + +G+++ +L GLE +
Sbjct: 894 VAWKHI--KESLGRPQGFEVGYWKDMEQED------TAETVKTRGNESFVILTGLEGNTL 945
Query: 924 YTLNVRVVNGKGEGPASPDRVFNTPEGVPS-APSSLKIVNPTLDSLTLEWDP 974
Y VR NG G GP S + T + PS APS+L+ ++L W+P
Sbjct: 946 YHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRWEQQG-SQVSLGWEP 996
Score = 46.6 bits (109), Expect = 2e-04
Identities = 36/133 (27%), Positives = 62/133 (46%), Gaps = 14/133 (10%)
Query: 39 LEDLVQPPTIT-QQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM 97
L+ L PT Q K I+ + +VI+C+ +G P P+ SW + + ++ + +
Sbjct: 473 LKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDR--AVRENKRIAI 530
Query: 98 KPGTGTLIINIMSEGKAETYEGVYQCTARNERGAA--VSNNIVVRPSRSPLWTKEKLEPI 155
P I+N +++ EG Y C N G+A +++ V P+R L K
Sbjct: 531 LPDGSLRILN-----ASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKR----T 581
Query: 156 TLQSGQSLVLPCR 168
L G+S+VL C+
Sbjct: 582 ELTVGESIVLNCK 594
Score = 40.8 bits (94), Expect = 0.009
Identities = 42/198 (21%), Positives = 80/198 (40%), Gaps = 12/198 (6%)
Query: 950 GVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQ-PINSTHELGPLVDLKIPA 1008
G P P + + T + TL W P + + ++ Y L+ + P + + V I
Sbjct: 669 GPPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITG 728
Query: 1009 NKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNP 1068
+ +LN Y+F A G+G T + +EA P V +
Sbjct: 729 DMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEA---VPKTAPTNVSGRSG 785
Query: 1069 RISNLTAAAAETYANISWEYEGPEHVNFYVEYGVAGSKEEWRKEIVNGSRS---FFGLKG 1125
R L A + +S E++ E + V + G++ W++++V S + + +
Sbjct: 786 RRHELVIA----WEPVSEEFQNGEGFGYIVAFRPNGTR-GWKEKMVTSSEASKFIYRDES 840
Query: 1126 LMPGTAYKVRVGAVGDSG 1143
+ P T ++V+VG + G
Sbjct: 841 VPPLTPFEVKVGVYNNKG 858
>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
Length = 1026
Score = 352 bits (904), Expect = 1e-96
Identities = 277/954 (29%), Positives = 423/954 (44%), Gaps = 82/954 (8%)
Query: 45 PPTITQQSPKDYIIDPRENIV-IQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 103
P I + SP + +D E V + CE KG P P W NGT D D ++ G+
Sbjct: 26 PIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGS-- 83
Query: 104 LIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSL 163
L+IN + K + G YQCTA N G VS ++ + + ++++ GQ +
Sbjct: 84 LLIN--NPNKTQD-AGTYQCTATNSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQGM 140
Query: 164 VLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFN 223
VL C PP W+ N + + R G+LY + V D +Y C
Sbjct: 141 VLLCGPPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVG-NYTCVV--- 196
Query: 224 HTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEEL 283
T T+ + + + ND + Y K + P T T
Sbjct: 197 -TNTVTNHKVLGPPTPLILR-NDGVMGE------YEPKIEVQFPETVPTA---------- 238
Query: 284 RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAK 343
+G + LEC A G P P I W + DG + L+I + + D+G Y+C+A+
Sbjct: 239 KGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKSNGILEIPNFQQEDAGLYECVAE 298
Query: 344 NALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEI 403
N+ G + A P WI ++ ++ E+ C+ANG PKP WL NG P+ +
Sbjct: 299 NSRGKNVARGQLTFYAQPNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGEPL-L 357
Query: 404 APDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP---RILTPA 460
D +I+ T+ + V + +YQC A N++G + +NA ++V+A P R L
Sbjct: 358 TRD--RIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKR 415
Query: 461 NTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDST 520
TL +V +++C SP P W KG +E I + E+G L I K
Sbjct: 416 VTLVKV--GGEVVIECKPKASPKPVYTWKKGRDILKENERI-TISEDGNLRIINVTKSDA 472
Query: 521 GTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVL 580
G+YTC+A N G A + +L +KDPT ++ P V G + C+V HDH+L +
Sbjct: 473 GSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFT 532
Query: 581 WLKDNRELPSDERFTVDKDH------------LVVADVSDDDSGTYTCVANTTLDSVSAS 628
W + + D D DH L++ ++ +G Y C+ T++D +SA+
Sbjct: 533 WSFNGHLIDFDR----DGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAA 588
Query: 629 AVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAM 688
A L V P P PP + + + D + QLSW PG DN+SPIT ++I+
Sbjct: 589 ADLIVRGP----------PGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPF 638
Query: 689 HKPGLWHHQTEV-----SGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKA 743
W + V T T + L+P+V Y FR +A N IG PS SE+ T+
Sbjct: 639 SVG--WQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEE 696
Query: 744 SEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEW--TSVVVA 801
+ P+ P V G G LVITW+ + NG G Y V++R G W T + A
Sbjct: 697 ALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPY-GKMIWMLTVLASA 755
Query: 802 NVSKYIV--SGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNS 859
+ S+Y+ F P+ +KV N+ G P + +S E+ P P ++ +++
Sbjct: 756 DASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSA 815
Query: 860 TLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLE 919
T EV W PL+ RG +QGY + YW+ + + R KI T G++T + L+
Sbjct: 816 TDIEVFW-ASPLEKNRGRIQGYEVKYWRHEDKEENAR-----KIRTV-GNQTSTKITNLK 868
Query: 920 PFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD 973
Y L V+ N G GP+S T + PS P I N + + L WD
Sbjct: 869 GSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWD 922
Score = 145 bits (367), Expect = 2e-34
Identities = 197/794 (24%), Positives = 308/794 (38%), Gaps = 107/794 (13%)
Query: 314 NRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALG----------AIHHTISVRVKAAP-Y 362
NR L I V ++D GNY C+ N + I V + P
Sbjct: 168 NRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKI 227
Query: 363 WITAPQNLVLSPGEDGTLICRANGNPKPRISWL-TNGVPIEIAPDDPSRKIDGDTIIFSN 421
+ P+ + + G L C A GNP P I W +G PI A K +G + N
Sbjct: 228 EVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPI--ARKARRHKSNG-ILEIPN 284
Query: 422 VQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGS 481
Q+ + +Y+C A N G +A + A+P I N ++ V +C G
Sbjct: 285 FQQEDAGLYECVAENSRGKNVARGQLTFYAQPNWI-QKINDIH-VAMEENVFWECKANGR 342
Query: 482 PLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLE 541
P PT +W K + + I + E GTL I + G Y C+A NK G+ + L
Sbjct: 343 PKPTYKWLKNGEPLLTRDRIQI--EQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELS 400
Query: 542 IKDPTWIVKQPEYA--------VVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDER 593
+ I P+++ +V+ G V ECK K T W K L +ER
Sbjct: 401 V-----IAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYT--WKKGRDILKENER 453
Query: 594 FTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFD 652
T+ +D +L + +V+ D+G+YTC+A + S++ L V PT V PP
Sbjct: 454 ITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTR-------VMVPPSS 506
Query: 653 LELTDQLDKSVQLSWTPGDDNNSPIT------KFIIEYEDAMHKPGLWHHQTEVSGTQTT 706
+++T + +S+ L D++ I +I+++ + G H V G +
Sbjct: 507 MDVT--VGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFD----RDG--DHFERVGGQDSA 558
Query: 707 AQLKLSPYVNYSFRVMAVNSIGKSLPS-EASEQYLTKASE-----PDKNPTAVEGLGSEP 760
L + R + + GK + + S L+ A++ P P AV
Sbjct: 559 GDLMI--------RNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITD 610
Query: 761 DNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSV------VVANVSKYIVSGTPTF 814
++W+P G +++ P Y + R W +V + V G +
Sbjct: 611 TTAQLSWRP--GPDNHSPITMYVIQARTPFSVG-WQAVSTVPELIDGKTFTATVVGLNPW 667
Query: 815 VPYLIKVQALNDMGFA-PEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKS 873
V Y + A N +G P + E LP V P NV + + + W+ VP +
Sbjct: 668 VEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEEL 727
Query: 874 IRGHLQGY--------RIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYT 925
G GY ++ + T +S R++ F+ H PFS +
Sbjct: 728 QNGRGFGYVVAFRPYGKMIWMLTVLASADASRYV------FRNESVH-------PFSPFE 774
Query: 926 LNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLE--WDPPSHPN-GIL 982
+ V V N KGEGP SP V + E P+ P + I +L + +E W P N G +
Sbjct: 775 VKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPA-SIFARSLSATDIEVFWASPLEKNRGRI 833
Query: 983 TEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITE 1042
Y +KY E + + N+T + NL S Y A SAG+G
Sbjct: 834 QGYEVKYWRHEDKEENARKI--RTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSAT 891
Query: 1043 EAVTTVDEAGILPP 1056
VTT PP
Sbjct: 892 VNVTTRKPPPSQPP 905
Score = 55.1 bits (131), Expect = 4e-07
Identities = 45/183 (24%), Positives = 79/183 (43%), Gaps = 6/183 (3%)
Query: 713 PYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITW-KPLN 771
P+ + +V N+ G+ S + Y + EP K P ++ ++ + W PL
Sbjct: 769 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAE-EEPTKPPASIFARSLSATDIEVFWASPLE 827
Query: 772 GFESNGPGLQYKVSWRQKDGDDEWTSV-VVANVSKYIVSGTPTFVPYLIKVQALNDMGFA 830
G + K WR +D ++ + V N + ++ V Y + V+A N G
Sbjct: 828 KNRGRIQGYEVKY-WRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTG 886
Query: 831 PEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYY-WKTQ 889
P A V + + P PGN+ N +S + ++WD V ++GY++ Y W Q
Sbjct: 887 PSSATVNVTTRKPPPSQPPGNIIWNSSDSKII-LNWDQVKALDNESEVKGYKVLYRWNRQ 945
Query: 890 SSS 892
SS+
Sbjct: 946 SST 948
>gi|7657361 contactin 6 [Homo sapiens]
Length = 1028
Score = 333 bits (855), Expect = 5e-91
Identities = 271/956 (28%), Positives = 404/956 (42%), Gaps = 73/956 (7%)
Query: 40 EDLVQPPTITQQSPKDYIID---PRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVT 96
+ L+ P TQ+ P D I + +++ C A G P P + W +NGT DID
Sbjct: 20 DGLLSRPIFTQE-PHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGT--DIDFTMSYH 76
Query: 97 MKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPIT 156
+ G+L IN + G+YQC A N G +S ++ + + + ++
Sbjct: 77 YRLDGGSLAIN---SPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVS 133
Query: 157 LQSGQSLVLPCRPPIGLPPPIIFWM--DNSFQRLPQSERVSQGLNGDLYFSNVLPEDTRE 214
++ GQ +VL C PP W DN + R G+LY + V P D
Sbjct: 134 VREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVG- 192
Query: 215 DYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPE 274
+Y C+ Q Q P + + D + Y K P T
Sbjct: 193 NYTCFITNKEAQRSVQGPPTPLV-----QRTDGVMGE------YEPKIEVRFPETI---- 237
Query: 275 GNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEAD 334
+ + + + LEC A G P P I W + DG + Y + L+I + + D
Sbjct: 238 ------QAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQED 291
Query: 335 SGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISW 394
G Y+CIA N G + A P W QN LS ++ C+A+G P P +W
Sbjct: 292 EGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTW 351
Query: 395 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 454
L NG E + +I+ T+I + + S VYQC A N+Y + ANA + VLA P
Sbjct: 352 LKNG---ERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAP 408
Query: 455 RIL-TPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIP 513
+P V ++ C P I W +G + + I++L E+G+L+I
Sbjct: 409 DFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLL-EDGSLKIY 467
Query: 514 VAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDH 573
+ G+YTC+A N+ G AKN L +K+ T I P V G + C+V HD
Sbjct: 468 NITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDP 527
Query: 574 TLSLTVLWLKDN------RELPSDERFTVDK-DHLVVADVSDDDSGTYTCVANTTLDSVS 626
++ + +W + + + ER + L++ ++ SG Y C TTL+S+S
Sbjct: 528 SIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLS 587
Query: 627 ASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYED 686
A A + V P P PP D+++ D + QLSW G DNNSPI F I+
Sbjct: 588 AVADIIVRGP----------PGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRT 637
Query: 687 AMHKPGLWHHQTEV-----SGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLT 741
W V T + LSP+V Y FRV+A NSIG PSE SE T
Sbjct: 638 PFSVG--WQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRT 695
Query: 742 KASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVA 801
KAS P P + G G LVITW+ + NG G Y + +R G W+ V+
Sbjct: 696 KASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPV-GSTTWSKEKVS 754
Query: 802 NVSK----YIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVV 857
+V Y P+ +KV N+ G V + +SGED P +AP +
Sbjct: 755 SVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSF 814
Query: 858 NSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPG 917
+++ EV W+ + G + GY + YW S + + G+ T + G
Sbjct: 815 SASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGK------IRVSGNVTTKNITG 868
Query: 918 LEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD 973
L+ + Y +VR N G GP+SP T + PS P + T L L W+
Sbjct: 869 LKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWE 924
Score = 117 bits (294), Expect = 6e-26
Identities = 173/772 (22%), Positives = 299/772 (38%), Gaps = 63/772 (8%)
Query: 314 NRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGA----------IHHTISVRVKAAP-Y 362
NR L I V +D GNY C N + T V + P
Sbjct: 170 NRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKI 229
Query: 363 WITAPQNLVLSPGEDGTLICRANGNPKPRISWLT-NGVPIEIAPDDPSRKIDGDTIIFSN 421
+ P+ + + L C A GNP P ISW +G P+ P + N
Sbjct: 230 EVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPL---PGKVKYSKSQAILEIPN 286
Query: 422 VQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGS 481
Q+ Y+C ASN G LA + A P NT + N L +C G
Sbjct: 287 FQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDN--LLWECKASGK 344
Query: 482 PLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGM--AKNEVH 539
P P W K G L+ + + ENGTL I + +G Y C A NK + A E+
Sbjct: 345 PNPWYTWLKN--GERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELR 402
Query: 540 LEIKDPTWIVKQP--EYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDER-FTV 596
+ P + K P + + VQ G + CK +++ W + L +R F +
Sbjct: 403 VLASAPDFS-KSPVKKKSFVQVGGDIVIGCKPNAFPRAAIS--WKRGTETLRQSKRIFLL 459
Query: 597 DKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELT 656
+ L + +++ D+G+YTC+A + + L V T V VP D+ +
Sbjct: 460 EDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERT-----VITVPPSKMDVTVG 514
Query: 657 DQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVN 716
+ + Q+S P + + + + K G+ H + + G + + ++
Sbjct: 515 ESIVLPCQVSHDPSIE---VVFVWFFNGDVIDLKKGVAHFE-RIGGESVGDLMIRNIQLH 570
Query: 717 YSFRVMA-VNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFES 775
+S + + V + +SL + A + + VE + S L +W+ G ++
Sbjct: 571 HSGKYLCTVQTTLESLSAVAD--IIVRGPPGPPEDVQVEDISSTTSQL--SWRA--GPDN 624
Query: 776 NGPGLQYKVSWRQKDGDDEWTSVV----VANVSKY--IVSGTPTFVPYLIKVQALNDMGF 829
N P + + R W +V + N Y V G +V Y +V A N +G
Sbjct: 625 NSPIQIFTIQTRTPFSVG-WQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGI 683
Query: 830 AP--EPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWK 887
EP+ ++ + +P+VAP N+ + + + W+ +P + G GY I +
Sbjct: 684 GEPSEPSELL-RTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRP 742
Query: 888 TQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNT 947
S++ ++K+ + + S+ + P S + + V V N +GEG S + +
Sbjct: 743 VGSTTWS-----KEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYS 797
Query: 948 PEGVPS-APSSLKIVNPTLDSLTLEWDPPS--HPNGILTEYTLKYQPINSTHELGPLVDL 1004
E P AP + + + + + W+ + G + Y + Y +S + + +
Sbjct: 798 GEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESM--IGKI 855
Query: 1005 KIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPP 1056
++ N T + L +T Y A +AG+G VTT PP
Sbjct: 856 RVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPP 907
Score = 33.5 bits (75), Expect = 1.4
Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 6/130 (4%)
Query: 700 VSGTQTTAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGS 758
VSG TT + L Y V A N+ G PS TK S P + P + +
Sbjct: 857 VSGNVTTKNITGLKANTIYFASVRAYNTAGTG-PSSPPVNVTTKKSPPSQPPANIAWKLT 915
Query: 759 EPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYL 818
L + W+ + E+ L YK+ +RQ + + + N S ++ P YL
Sbjct: 916 N-SKLCLNWEHVKTMENESEVLGYKILYRQ-NRQSKTHILETNNTSAELL--VPFEEDYL 971
Query: 819 IKVQALNDMG 828
I+++ ++D G
Sbjct: 972 IEIRTVSDGG 981
>gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]
Length = 1018
Score = 308 bits (789), Expect = 2e-83
Identities = 262/958 (27%), Positives = 413/958 (43%), Gaps = 102/958 (10%)
Query: 64 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQC 123
+ + C A+ P P + W N D+ D + G L+IN + K G+Y C
Sbjct: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVG---GNLVINNPDKQKDA---GIYYC 114
Query: 124 TARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIF-WMD 182
A N G S + + E+ + ++ G+ +VL C PP P + + W+
Sbjct: 115 LASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLL 174
Query: 183 NSFQ---RLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARF-NHTQTIQQKQPISVKV 238
N F + + VSQ NG+LY +NV D + +Y C+ + T+++ K + +
Sbjct: 175 NEFPVFITMDKRRFVSQ-TNGNLYIANVEASD-KGNYSCFVSSPSITKSVFSK---FIPL 229
Query: 239 ISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLP 298
I + E ++++ P + + L G ++LEC A G P
Sbjct: 230 IPIPE-----------------RTTKPYPADIVV---QFKDVYALMGQNVTLECFALGNP 269
Query: 299 TPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVK 358
P I W K +P + + L+I ++ D G Y+C A+N G H + V+
Sbjct: 270 VPDIRWRKVLEPMPSTAEISTS-GAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQ 328
Query: 359 AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII 418
A P W+ + + G D C A G P P I WL NG G+ +
Sbjct: 329 AFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYH----------KGELRL 378
Query: 419 FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI-LTPANTLYQVIANRPALLDCA 477
+ +V ++ +YQC A N YG + ANA + +LA P + P +++C
Sbjct: 379 Y-DVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECK 437
Query: 478 FFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNE 537
+P P W KG + ++ ++ E+G+LEI ++ G YTC A N G A +
Sbjct: 438 PKAAPKPKFSWSKGTEW-LVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANST 496
Query: 538 VHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW------LKDNRE-LPS 590
L I DPT I+ P A + G + +C D L LT +W + N+E +
Sbjct: 497 GTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHY 556
Query: 591 DERFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNP 649
F +D + L++ + +G YTC A T +D+ SASA L V P P P
Sbjct: 557 QRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGP----------PGP 606
Query: 650 PFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIE--------YEDAMHKPGLWHHQTEVS 701
P L + D SV L+W+ G DN+SPI+K+ I+ ++DA P + +
Sbjct: 607 PGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPI------IE 660
Query: 702 GTQTTAQ-LKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEP 760
G A+ + L P++ Y FRV+A N++G+ PS S + T + P+ P+ V G G
Sbjct: 661 GNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRN 720
Query: 761 DNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVAN--VSKYIVSGTPTFVP-- 816
L ITW PL+ G Y V+++ DG +EW V V N +Y V T P
Sbjct: 721 RELTITWAPLSREYHYGNNFGYIVAFKPFDG-EEWKKVTVTNPDTGRY-VHKDETMSPST 778
Query: 817 -YLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIR 875
+ +KV+A N+ G P V + +S +D P AP V V V++S+ VHW+ V K +
Sbjct: 779 AFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIV- 837
Query: 876 GHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKG 935
+ Y+I YW + R + + L L P + Y + V N G
Sbjct: 838 ---ESYQIRYWAAHDKEEAANR------VQVTSQEYSARLENLLPDTQYFIEVGACNSAG 888
Query: 936 EGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD--PPSHPNGILTEYTLKYQP 991
GP S T + PS P + + + WD +T Y + Y+P
Sbjct: 889 CGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRP 946
Score = 83.6 bits (205), Expect = 1e-15
Identities = 96/392 (24%), Positives = 158/392 (40%), Gaps = 39/392 (9%)
Query: 265 ERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT 324
E+P + PE E L G V SL C A P P+ W +G + Y
Sbjct: 45 EQPINTIYPE------ESLEGKV-SLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGN 97
Query: 325 LQIIHV-SEADSGNYQCIAKNALGAIHHTISVRV--KAAPYWITAPQNLVLSPGEDGTLI 381
L I + + D+G Y C+A N G + T + P+ + + G+ L+
Sbjct: 98 LVINNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLL 157
Query: 382 CRANGNPKPRIS--WLTNGVPIEIAPDDPSRKIDGDT---IIFSNVQERSSAVYQCNASN 436
C + +S WL N P+ I D R+ T + +NV+ Y C S+
Sbjct: 158 CDPPYHFPDDLSYRWLLNEFPVFITMD--KRRFVSQTNGNLYIANVEASDKGNYSCFVSS 215
Query: 437 -EYGYLLANAFVNVLAEPPRILT--PANTLYQ-----VIANRPALLDCAFFGSPLPTIEW 488
+ + F+ ++ P R PA+ + Q + + L+C G+P+P I W
Sbjct: 216 PSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRW 275
Query: 489 FKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD-PTW 547
K + +I L+I Q + G Y C A N G K++ + ++ P W
Sbjct: 276 RKVLEPMPSTAEIST--SGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEW 333
Query: 548 IVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVS 607
V+ V GS + + C T+ WLK+ + K L + DV+
Sbjct: 334 -VEHINDTEVDIGSDLYWPCVATGKPI--PTIRWLKNG--------YAYHKGELRLYDVT 382
Query: 608 DDDSGTYTCVANTTLDSVSASAVLSVVAPTPT 639
+++G Y C+A T ++ A+A L ++A PT
Sbjct: 383 FENAGMYQCIAENTYGAIYANAELKILALAPT 414
Score = 73.2 bits (178), Expect = 2e-12
Identities = 95/427 (22%), Positives = 164/427 (38%), Gaps = 73/427 (17%)
Query: 45 PPTITQQSPKDYIIDPRE-------NIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM 97
P T+ P D ++ ++ N+ ++C A G P P W + ++ P
Sbjct: 233 PERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK-----VLEPMPSTAE 287
Query: 98 KPGTGTL--IINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPI 155
+G + I NI E EG+Y+C A N RG + + P W E +
Sbjct: 288 ISTSGAVLKIFNIQLED-----EGIYECEAENIRGKD-KHQARIYVQAFPEWV-EHINDT 340
Query: 156 TLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTRED 215
+ G L PC G P P I W+ N + R+ D+ F N
Sbjct: 341 EVDIGSDLYWPC-VATGKPIPTIRWLKNGYAYHKGELRLY-----DVTFENA------GM 388
Query: 216 YICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEG 275
Y C A + + +K++++ PTF E
Sbjct: 389 YQCIAENTYGAIYANAE---LKILAL-------------------------APTF---EM 417
Query: 276 NASNKEEL--RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEA 333
N K+ L +G + +EC + P P W+K L + + + +L+I +++
Sbjct: 418 NPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRN 477
Query: 334 DSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRIS 393
D G Y C A+N G + T ++ + I AP N ++ GE+ T+ C A+ +P ++
Sbjct: 478 DGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLT 537
Query: 394 --WLTNGVPIEIAPDD----PSRKIDGD-TIIFSNVQERSSAVYQCNASNEYGYLLANAF 446
W NG I+ ++ + +D + ++ N Q + + Y C A A+A
Sbjct: 538 FVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASAD 597
Query: 447 VNVLAEP 453
+ V P
Sbjct: 598 LVVRGPP 604
Score = 44.7 bits (104), Expect = 6e-04
Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 8/102 (7%)
Query: 39 LEDLVQPPTITQQSPKDYIIDPREN-IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM 97
L+ L PT K I+ + ++I+C+ K P P FSW++ GT + ++ ++
Sbjct: 406 LKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK-GTEWLVNSSRILIW 464
Query: 98 KPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 139
+ G+L IN ++ G+Y C A N RG A S +V
Sbjct: 465 E--DGSLEINNITRNDG----GIYTCFAENNRGKANSTGTLV 500
Score = 43.5 bits (101), Expect = 0.001
Identities = 76/347 (21%), Positives = 128/347 (36%), Gaps = 41/347 (11%)
Query: 817 YLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRG 876
Y Q + D A VV G G PG +R+ + +T + W RG
Sbjct: 581 YTCTAQTIVDNSSASADLVVRGPPGP------PGGLRIEDIRATSVALTWS-------RG 627
Query: 877 HLQGYRI--YYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGK 934
I Y +T++ + + + +G+ L P+ Y V N
Sbjct: 628 SDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTL 687
Query: 935 GEG-PASPDRVFNTPEGVPS-APSSLKIVNPTLDSLTLEWDPPS--HPNGILTEYTLKYQ 990
G G P+ P T P+ APS + LT+ W P S + G Y + ++
Sbjct: 688 GRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFK 747
Query: 991 PINSTHELGPLVDLKIPANKTRWTLKN--LNFSTRYKFYFYAQTSAGSGSQITEEAVTTV 1048
P + E V + P + R+ K+ ++ ST ++ A + G G + +
Sbjct: 748 PFDG--EEWKKVTVTNP-DTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSA 804
Query: 1049 DEA-GILPPDVGAGKVQAVNPRISNLTAAAAETYANISWEYEGPEHVNFY-VEYGVAGSK 1106
+A P +VG + + ++ WE+ + V Y + Y A K
Sbjct: 805 QDAPSEAPTEVGV--------------KVLSSSEISVHWEHVLEKIVESYQIRYWAAHDK 850
Query: 1107 EEWRKEIVNGSRSFFG-LKGLMPGTAYKVRVGAVGDSGFVSSEDVFE 1152
EE + S+ + L+ L+P T Y + VGA +G D+ E
Sbjct: 851 EEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIE 897
>gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens]
Length = 1007
Score = 308 bits (789), Expect = 2e-83
Identities = 262/958 (27%), Positives = 413/958 (43%), Gaps = 102/958 (10%)
Query: 64 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQC 123
+ + C A+ P P + W N D+ D + G L+IN + K G+Y C
Sbjct: 50 VSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVG---GNLVINNPDKQKDA---GIYYC 103
Query: 124 TARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIF-WMD 182
A N G S + + E+ + ++ G+ +VL C PP P + + W+
Sbjct: 104 LASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLL 163
Query: 183 NSFQ---RLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARF-NHTQTIQQKQPISVKV 238
N F + + VSQ NG+LY +NV D + +Y C+ + T+++ K + +
Sbjct: 164 NEFPVFITMDKRRFVSQ-TNGNLYIANVEASD-KGNYSCFVSSPSITKSVFSK---FIPL 218
Query: 239 ISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLP 298
I + E ++++ P + + L G ++LEC A G P
Sbjct: 219 IPIPE-----------------RTTKPYPADIVV---QFKDVYALMGQNVTLECFALGNP 258
Query: 299 TPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVK 358
P I W K +P + + L+I ++ D G Y+C A+N G H + V+
Sbjct: 259 VPDIRWRKVLEPMPSTAEISTS-GAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQ 317
Query: 359 AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII 418
A P W+ + + G D C A G P P I WL NG G+ +
Sbjct: 318 AFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYH----------KGELRL 367
Query: 419 FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI-LTPANTLYQVIANRPALLDCA 477
+ +V ++ +YQC A N YG + ANA + +LA P + P +++C
Sbjct: 368 Y-DVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECK 426
Query: 478 FFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNE 537
+P P W KG + ++ ++ E+G+LEI ++ G YTC A N G A +
Sbjct: 427 PKAAPKPKFSWSKGTEW-LVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANST 485
Query: 538 VHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW------LKDNRE-LPS 590
L I DPT I+ P A + G + +C D L LT +W + N+E +
Sbjct: 486 GTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHY 545
Query: 591 DERFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNP 649
F +D + L++ + +G YTC A T +D+ SASA L V P P P
Sbjct: 546 QRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGP----------PGP 595
Query: 650 PFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIE--------YEDAMHKPGLWHHQTEVS 701
P L + D SV L+W+ G DN+SPI+K+ I+ ++DA P + +
Sbjct: 596 PGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPI------IE 649
Query: 702 GTQTTAQ-LKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEP 760
G A+ + L P++ Y FRV+A N++G+ PS S + T + P+ P+ V G G
Sbjct: 650 GNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRN 709
Query: 761 DNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVAN--VSKYIVSGTPTFVP-- 816
L ITW PL+ G Y V+++ DG +EW V V N +Y V T P
Sbjct: 710 RELTITWAPLSREYHYGNNFGYIVAFKPFDG-EEWKKVTVTNPDTGRY-VHKDETMSPST 767
Query: 817 -YLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIR 875
+ +KV+A N+ G P V + +S +D P AP V V V++S+ VHW+ V K +
Sbjct: 768 AFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIV- 826
Query: 876 GHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKG 935
+ Y+I YW + R + + L L P + Y + V N G
Sbjct: 827 ---ESYQIRYWAAHDKEEAANR------VQVTSQEYSARLENLLPDTQYFIEVGACNSAG 877
Query: 936 EGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD--PPSHPNGILTEYTLKYQP 991
GP S T + PS P + + + WD +T Y + Y+P
Sbjct: 878 CGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRP 935
Score = 83.6 bits (205), Expect = 1e-15
Identities = 96/392 (24%), Positives = 158/392 (40%), Gaps = 39/392 (9%)
Query: 265 ERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT 324
E+P + PE E L G V SL C A P P+ W +G + Y
Sbjct: 34 EQPINTIYPE------ESLEGKV-SLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGN 86
Query: 325 LQIIHV-SEADSGNYQCIAKNALGAIHHTISVRV--KAAPYWITAPQNLVLSPGEDGTLI 381
L I + + D+G Y C+A N G + T + P+ + + G+ L+
Sbjct: 87 LVINNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLL 146
Query: 382 CRANGNPKPRIS--WLTNGVPIEIAPDDPSRKIDGDT---IIFSNVQERSSAVYQCNASN 436
C + +S WL N P+ I D R+ T + +NV+ Y C S+
Sbjct: 147 CDPPYHFPDDLSYRWLLNEFPVFITMD--KRRFVSQTNGNLYIANVEASDKGNYSCFVSS 204
Query: 437 -EYGYLLANAFVNVLAEPPRILT--PANTLYQ-----VIANRPALLDCAFFGSPLPTIEW 488
+ + F+ ++ P R PA+ + Q + + L+C G+P+P I W
Sbjct: 205 PSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRW 264
Query: 489 FKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD-PTW 547
K + +I L+I Q + G Y C A N G K++ + ++ P W
Sbjct: 265 RKVLEPMPSTAEIST--SGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEW 322
Query: 548 IVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVS 607
V+ V GS + + C T+ WLK+ + K L + DV+
Sbjct: 323 -VEHINDTEVDIGSDLYWPCVATGKPI--PTIRWLKNG--------YAYHKGELRLYDVT 371
Query: 608 DDDSGTYTCVANTTLDSVSASAVLSVVAPTPT 639
+++G Y C+A T ++ A+A L ++A PT
Sbjct: 372 FENAGMYQCIAENTYGAIYANAELKILALAPT 403
Score = 73.2 bits (178), Expect = 2e-12
Identities = 95/427 (22%), Positives = 164/427 (38%), Gaps = 73/427 (17%)
Query: 45 PPTITQQSPKDYIIDPRE-------NIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM 97
P T+ P D ++ ++ N+ ++C A G P P W + ++ P
Sbjct: 222 PERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK-----VLEPMPSTAE 276
Query: 98 KPGTGTL--IINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPI 155
+G + I NI E EG+Y+C A N RG + + P W E +
Sbjct: 277 ISTSGAVLKIFNIQLED-----EGIYECEAENIRGKD-KHQARIYVQAFPEWV-EHINDT 329
Query: 156 TLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTRED 215
+ G L PC G P P I W+ N + R+ D+ F N
Sbjct: 330 EVDIGSDLYWPC-VATGKPIPTIRWLKNGYAYHKGELRLY-----DVTFENA------GM 377
Query: 216 YICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEG 275
Y C A + + +K++++ PTF E
Sbjct: 378 YQCIAENTYGAIYANAE---LKILAL-------------------------APTF---EM 406
Query: 276 NASNKEEL--RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEA 333
N K+ L +G + +EC + P P W+K L + + + +L+I +++
Sbjct: 407 NPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRN 466
Query: 334 DSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRIS 393
D G Y C A+N G + T ++ + I AP N ++ GE+ T+ C A+ +P ++
Sbjct: 467 DGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLT 526
Query: 394 --WLTNGVPIEIAPDD----PSRKIDGD-TIIFSNVQERSSAVYQCNASNEYGYLLANAF 446
W NG I+ ++ + +D + ++ N Q + + Y C A A+A
Sbjct: 527 FVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASAD 586
Query: 447 VNVLAEP 453
+ V P
Sbjct: 587 LVVRGPP 593
Score = 44.7 bits (104), Expect = 6e-04
Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 8/102 (7%)
Query: 39 LEDLVQPPTITQQSPKDYIIDPREN-IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM 97
L+ L PT K I+ + ++I+C+ K P P FSW++ GT + ++ ++
Sbjct: 395 LKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK-GTEWLVNSSRILIW 453
Query: 98 KPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 139
+ G+L IN ++ G+Y C A N RG A S +V
Sbjct: 454 E--DGSLEINNITRNDG----GIYTCFAENNRGKANSTGTLV 489
Score = 43.5 bits (101), Expect = 0.001
Identities = 76/347 (21%), Positives = 128/347 (36%), Gaps = 41/347 (11%)
Query: 817 YLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRG 876
Y Q + D A VV G G PG +R+ + +T + W RG
Sbjct: 570 YTCTAQTIVDNSSASADLVVRGPPGP------PGGLRIEDIRATSVALTWS-------RG 616
Query: 877 HLQGYRI--YYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGK 934
I Y +T++ + + + +G+ L P+ Y V N
Sbjct: 617 SDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTL 676
Query: 935 GEG-PASPDRVFNTPEGVPS-APSSLKIVNPTLDSLTLEWDPPS--HPNGILTEYTLKYQ 990
G G P+ P T P+ APS + LT+ W P S + G Y + ++
Sbjct: 677 GRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFK 736
Query: 991 PINSTHELGPLVDLKIPANKTRWTLKN--LNFSTRYKFYFYAQTSAGSGSQITEEAVTTV 1048
P + E V + P + R+ K+ ++ ST ++ A + G G + +
Sbjct: 737 PFDG--EEWKKVTVTNP-DTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSA 793
Query: 1049 DEA-GILPPDVGAGKVQAVNPRISNLTAAAAETYANISWEYEGPEHVNFY-VEYGVAGSK 1106
+A P +VG + + ++ WE+ + V Y + Y A K
Sbjct: 794 QDAPSEAPTEVGV--------------KVLSSSEISVHWEHVLEKIVESYQIRYWAAHDK 839
Query: 1107 EEWRKEIVNGSRSFFG-LKGLMPGTAYKVRVGAVGDSGFVSSEDVFE 1152
EE + S+ + L+ L+P T Y + VGA +G D+ E
Sbjct: 840 EEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIE 886
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 272 bits (695), Expect = 2e-72
Identities = 296/1175 (25%), Positives = 480/1175 (40%), Gaps = 115/1175 (9%)
Query: 29 ALEVPLDPKLLEDLVQPPTITQQS-PKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHF 87
AL++ L L +D V P T+ P+ ++ R +V+ C A+G P F W R+
Sbjct: 88 ALQLHLLRALAQDDVAPYFKTEPGLPQIHLEGNR--LVLTCLAEGSWPLEFKWMRD---- 141
Query: 88 DIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVS--NNIVVRPSRSP 145
D +T II + + A G Y+C RN GA + + + V S
Sbjct: 142 ----DSELTTYSSEYKYIIPSLQKLDA----GFYRCVVRNRMGALLQRKSEVQVAYMGSF 193
Query: 146 LWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFS 205
+ T ++ T+ G++ +L P P P + W + +P S R++ L L
Sbjct: 194 MDTDQRK---TVSQGRAAILNLLPITSYPRPQVTWFREGHKIIP-SNRIAITLENQLVIL 249
Query: 206 NVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRE 265
D Y+ Q + +K E + +LS G +
Sbjct: 250 ATTTSDAGAYYV--------QAVNEKN---------GENKTSPFIHLSIARDVGTPETMA 292
Query: 266 RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP--IIYWAKEDGMLPKNRTVYKNFEK 323
PT + P GN S + +LECIA P + W K +G+ + + +F +
Sbjct: 293 --PTIVVPPGNRS--VVAGSSETTLECIASARPVEDLSVTW-KRNGV--RITSGLHSFGR 345
Query: 324 TLQIIHVSEADSGNYQCIAK---NALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTL 380
L I + + AD+G Y C A +A T + + PY+ P++ + + E+
Sbjct: 346 RLTISNPTSADTGPYVCEAALPGSAFEPARATAFLFIIEPPYFTAEPESRISAEVEETVD 405
Query: 381 I-CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYG 439
I C+A G P P + W + + I + + + + ++ S ++QC ASNE G
Sbjct: 406 IGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGGLRIQKLRPEDSGIFQCFASNEGG 465
Query: 440 YLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKG----AKGS 495
+ + +++V P + T V A+L C G+P P I W + A GS
Sbjct: 466 EIQTHTYLDVTNIAP-VFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGS 524
Query: 496 ALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYA 555
+ ++L E+G L+I G YTC A N G L + + T IV PE
Sbjct: 525 -VRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDH 583
Query: 556 VVQRGSMVSFECKVKHDHTLSLTVLWLKDNREL--PSDERFTVDKD-HLVVADVSDDDSG 612
VV +G+ + C HD +SL +W KDN L S R V+KD L+++ D G
Sbjct: 584 VVIKGTTATLHCGATHDPRVSLRYVWKKDNVALTPSSTSRIVVEKDGSLLISQTWSGDIG 643
Query: 613 TYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDD 672
Y+C + + S A L V+ +P + PN +V LSW D
Sbjct: 644 DYSCEIVSEGGNDSRMARLEVIELPHSPQNLLVSPN--------SSHSHAVVLSWVRPFD 695
Query: 673 NNSPITKFIIEYED--AMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKS 730
NSPI +I+E + + K L + E++G + L+P Y FRV AVN +G+
Sbjct: 696 GNSPILYYIVELSENNSPWKVHLSNVGPEMTGVTVSG---LTPARTYQFRVCAVNEVGRG 752
Query: 731 LPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQK- 789
S + + + P P + G ++++ W+P E NG Y + +R
Sbjct: 753 QYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAG 812
Query: 790 -DGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVA 848
G+ + ++ V+ +V+ + Y I+V A N G V ++ + +P
Sbjct: 813 LPGEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAP 872
Query: 849 PGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQG 908
P NV+ VNST + W+P P + I G QGY++ W + I F G
Sbjct: 873 PQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVTIAP---DFHG 929
Query: 909 SKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSL 968
HG + L+ F+ Y +V G+GP S ++ T E P A L SL
Sbjct: 930 VH-HGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSL 988
Query: 969 TLEWDPPSHPNGILTEYTLKYQPINS-----THELGPLVDLKIPANKTRWTLKNLNFSTR 1023
+ W P NGI+T Y + ++ TH L + + ++ L+ T
Sbjct: 989 KVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHTLN--------STTHEYKIQGLSSLTT 1040
Query: 1024 YKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYAN 1083
Y A T+ G+G VT+ + +PPD+ V ISN++ +A
Sbjct: 1041 YTIDVAAVTAVGTG------LVTSSTISSGVPPDLPGAPSNLV---ISNISPRSATLQFR 1091
Query: 1084 ISWEYEGPEHVNFYV---EYGVAGSKEEW---RKEIVNGSRSFFGLKGLMPGTAYKVR-- 1135
Y+G ++ ++ + G G +EEW +E + L P T Y+ R
Sbjct: 1092 PG--YDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMK 1149
Query: 1136 -VGAVGDSGFVSSEDVFET---GPAMASRQVDIAT 1166
V VG S + S V +T P +A V + T
Sbjct: 1150 QVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRT 1184
Score = 176 bits (445), Expect = 2e-43
Identities = 168/688 (24%), Positives = 288/688 (41%), Gaps = 72/688 (10%)
Query: 647 PNPPFDLELTDQLD---KSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGT 703
P PP +L L Q + +S++L W PG D SPI F ++ + G W +
Sbjct: 1477 PAPPREL-LVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPR--GEWQTYSSSISH 1533
Query: 704 QTTAQL--KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPD 761
+ TA + +L P+ +Y R+ A N IG S S +E T P + P +V
Sbjct: 1534 EATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTS 1593
Query: 762 NLVITWKPLNGFESNGPGLQYKVSWRQKD-----GDDEWT--------SVVVANVSKYIV 808
+++I W+P NG Y++ +R+ + G + T + + A S V
Sbjct: 1594 SVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTV 1653
Query: 809 SGTPT-----------FVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVV 857
+ + T + Y + + A N +G +P A V GE P +AP NV+V +
Sbjct: 1654 NSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPL 1713
Query: 858 NSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPG 917
++ EV WDP P +S G++QGY+IYYW+ S ++ + K+L L
Sbjct: 1714 TASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEK----MKVLFLPEPVVR--LKN 1767
Query: 918 LEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSH 977
L + Y +++ N G+GP S + T + P APS L T +L + W P+
Sbjct: 1768 LTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAA 1827
Query: 978 PNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1037
NGIL Y + Y+P+ + +V +++ N RW LK + + ++F Q
Sbjct: 1828 ANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRW-LKVRDLTKGVTYFFRVQ------ 1880
Query: 1038 SQITEEAVTTVDEAGILPPDVGAGKVQAV--NPRISNLTAAAAETYANISWEYEGPEHVN 1095
T+ L ++ AG + +PR +T +A+E + + G
Sbjct: 1881 -------ARTITYGPELQANITAGPAEGSPGSPRDVLVTKSASELTLQWTEGHSGDTPTT 1933
Query: 1096 FYVEYGVAGSKEEWR---KEIVNGSRSF-FGLKGLMPGTAYKVRVGAVGDSGFVSSEDVF 1151
YV + W K+I + S+ L L G Y+ RV AV ++G+ E
Sbjct: 1934 GYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGY--GEPSN 1991
Query: 1152 ETGPAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPE 1211
+ A + + WF+ +M +L++++L++ + + KY ++
Sbjct: 1992 PSTAVSAQVEAPFYEEWWFLLVMALSSLIVILLVVFALVLHGQNKKY-----KNCSTGKG 2046
Query: 1212 IQPMKE----DDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQFN 1267
I M+E D+G F + H +K + S L E + ++N
Sbjct: 2047 ISTMEESVTLDNGGFAALELSSRHLNVKSTFSKKNGTRSPPRPSPGGLHYSDEDICNKYN 2106
Query: 1268 EDGSFIGQYSGKKEKEPAEGNESSEAPS 1295
G+ + + KEK A+ +ES S
Sbjct: 2107 --GAVLTESVSLKEKS-ADASESEATDS 2131
Score = 154 bits (388), Expect = 7e-37
Identities = 140/554 (25%), Positives = 243/554 (43%), Gaps = 43/554 (7%)
Query: 621 TLDSVSASAVLS--VVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPIT 678
T+D + +AV + V + T + D+P P +L +++ +S L + PG D + I+
Sbjct: 1042 TIDVAAVTAVGTGLVTSSTISSGVPPDLPGAPSNLVISNISPRSATLQFRPGYDGKTSIS 1101
Query: 679 KFIIEYE-----DAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPS 733
++I+E + D L+ + E Q L+PY +Y FR+ VN +G S S
Sbjct: 1102 RWIVEGQVGAIGDEEEWVTLYEEENEPDA-QMLEIPNLTPYTHYRFRMKQVNIVGPSPYS 1160
Query: 734 EASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNG--PGLQYKVSWRQKDG 791
+S T + PD PT+V + +L + W PL + NG + Y++ + + D
Sbjct: 1161 PSSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDL 1220
Query: 792 DDEWTSVVVAN--VSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAP 849
+ VV++ ++ + ++ Y +++QA N +G P VV G + E +P AP
Sbjct: 1221 QSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAP 1280
Query: 850 GNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGS 909
NV V+ST + W VP + G + GY+I + + + R HI +G+
Sbjct: 1281 ENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILF-RAKDLDPEPRSHI------VRGN 1333
Query: 910 KTH-GMLPGLEPFSHYTLNVRVVNGKGEG-PASPDRVFNTPEGVPSAPSSLKIVNPTLDS 967
T +L GL F Y L V G G P++P + T + P P L L S
Sbjct: 1334 HTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTS 1393
Query: 968 LTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFY 1027
+ + W PP PNGI+ Y + Y+ +S+ +++ A ++T +L + Y F
Sbjct: 1394 VRIVWQPPEEPNGIILGYQIAYRLASSSPH--TFTTVEVGATVRQFTATDLAPESAYIFR 1451
Query: 1028 FYAQTSAGSGSQITEEAVTTVDEAGILPPD---VGAGKVQAVNPRISNLTAAAAETYANI 1084
A+T G G + +TT PP V +V A + R+ + +
Sbjct: 1452 LSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGS-------- 1503
Query: 1085 SWEYEGPEHVNFYVEYGVAGSKEEWR--KEIVNGSRSFFGLKGLMPGTAYKVRVGA---V 1139
+G + ++ + EW+ ++ + + L P T+YK+R+ A +
Sbjct: 1504 ----DGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDI 1559
Query: 1140 GDSGFVSSEDVFET 1153
GDS F S + T
Sbjct: 1560 GDSDFSSETEAVTT 1573
Score = 109 bits (273), Expect = 2e-23
Identities = 131/511 (25%), Positives = 204/511 (39%), Gaps = 43/511 (8%)
Query: 645 DVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQ 704
D P PP L + SV++ W P ++ N I + I Y A P H T V
Sbjct: 1376 DAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSP---HTFTTVEVGA 1432
Query: 705 TTAQLK---LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEP-DKNPTAVEGLGSEP 760
T Q L+P Y FR+ A G P EA+ K P V
Sbjct: 1433 TVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTA 1492
Query: 761 DNLVITWKPLNGFESNGPGLQYKVSWRQKDGDD--EWTSVVVANVSKYIVSGTPTFVPYL 818
+L + W P G + P + + R+ + ++S + + +V F Y
Sbjct: 1493 RSLRLQWVP--GSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYK 1550
Query: 819 IKVQALNDMG---FAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIR 875
++++A ND+G F+ E V + +D+P PG+V ++ + W P +S+
Sbjct: 1551 LRLKATNDIGDSDFSSETEAVT--TLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLN 1608
Query: 876 GHLQGYRIYYWK--------TQSSSKRN--RRHIE----KKILTFQGSKTHGM--LPGLE 919
G LQGYRIYY + T++ + +N H E T S T M L L+
Sbjct: 1609 GLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLK 1668
Query: 920 PFSHYTLNVRVVNGKGEGPAS-PDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD--PPS 976
+ Y + + N GE PAS P VF AP ++++ T L + WD PP
Sbjct: 1669 KYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPE 1728
Query: 977 HPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGS 1036
NG + Y + Y +S +E + L +P R LKNL T+Y A +AG
Sbjct: 1729 SQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVR--LKNLTSHTKYLVSISAFNAAGD 1786
Query: 1037 GSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAA----ETYANISWEYEGPE 1092
G + + T A P + ++ + +S AAA + Y + +
Sbjct: 1787 GPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQ 1846
Query: 1093 HVNFYVEYGVAGSKEEWRK--EIVNGSRSFF 1121
V+ V V G+ + W K ++ G FF
Sbjct: 1847 GVSKVVTVEVRGNWQRWLKVRDLTKGVTYFF 1877
Score = 47.0 bits (110), Expect = 1e-04
Identities = 36/112 (32%), Positives = 47/112 (41%), Gaps = 7/112 (6%)
Query: 639 TPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWH--- 695
T P P P D+ +T + + L WT G ++P T ++IE + GLW
Sbjct: 1895 TAGPAEGSPGSPRDVLVTKSASE-LTLQWTEGHSGDTPTTGYVIEARPS--DEGLWDMFV 1951
Query: 696 HQTEVSGTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEP 746
S T T L KL V Y FRV+AVN G PS S + P
Sbjct: 1952 KDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAP 2003
>gi|28373126 contactin 4 isoform c precursor [Homo sapiens]
Length = 698
Score = 265 bits (676), Expect = 3e-70
Identities = 191/616 (31%), Positives = 288/616 (46%), Gaps = 54/616 (8%)
Query: 382 CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL 441
C+ANG PKP WL NG P+ + D +I+ T+ + V + +YQC A N++G +
Sbjct: 9 CKANGRPKPTYKWLKNGEPL-LTRD--RIQIEQGTLNITIVNLSDAGMYQCLAENKHGVI 65
Query: 442 LANAFVNVLAEPP---RILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALH 498
+NA ++V+A P R L TL +V +++C SP P W KG +
Sbjct: 66 FSNAELSVIAVGPDFSRTLLKRVTLVKV--GGEVVIECKPKASPKPVYTWKKGRDILKEN 123
Query: 499 EDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQ 558
E I + E+G L I K G+YTC+A N G A + +L +KDPT ++ P V
Sbjct: 124 ERI-TISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVT 182
Query: 559 RGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH------------LVVADV 606
G + C+V HDH+L + W + + D D DH L++ ++
Sbjct: 183 VGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDR----DGDHFERVGGQDSAGDLMIRNI 238
Query: 607 SDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLS 666
+G Y C+ T++D +SA+A L V P P PP + + + D + QLS
Sbjct: 239 QLKHAGKYVCMVQTSVDRLSAAADLIVRGP----------PGPPEAVTIDEITDTTAQLS 288
Query: 667 WTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEV-----SGTQTTAQLKLSPYVNYSFRV 721
W PG DN+SPIT ++I+ W + V T T + L+P+V Y FR
Sbjct: 289 WRPGPDNHSPITMYVIQARTPFSVG--WQAVSTVPELIDGKTFTATVVGLNPWVEYEFRT 346
Query: 722 MAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQ 781
+A N IG PS SE+ T+ + P+ P V G G LVITW+ + NG G
Sbjct: 347 VAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFG 406
Query: 782 YKVSWRQKDGDDEW--TSVVVANVSKYIV--SGTPTFVPYLIKVQALNDMGFAPEPAVVM 837
Y V++R G W T + A+ S+Y+ F P+ +KV N+ G P +
Sbjct: 407 YVVAFRPY-GKMIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTV 465
Query: 838 GHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRR 897
+S E+ P P ++ +++T EV W PL+ RG +QGY + YW+ + + R
Sbjct: 466 VYSAEEEPTKPPASIFARSLSATDIEVFW-ASPLEKNRGRIQGYEVKYWRHEDKEENAR- 523
Query: 898 HIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSS 957
KI T G++T + L+ Y L V+ N G GP+S T + PS P
Sbjct: 524 ----KIRTV-GNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPG 578
Query: 958 LKIVNPTLDSLTLEWD 973
I N + + L WD
Sbjct: 579 NIIWNSSDSKIILNWD 594
Score = 115 bits (289), Expect = 2e-25
Identities = 153/623 (24%), Positives = 243/623 (39%), Gaps = 94/623 (15%)
Query: 475 DCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMA 534
+C G P PT +W K + + I + E GTL I + G Y C+A NK G+
Sbjct: 8 ECKANGRPKPTYKWLKNGEPLLTRDRIQI--EQGTLNITIVNLSDAGMYQCLAENKHGVI 65
Query: 535 KNEVHLEIKDPTWIVKQPEYA--------VVQRGSMVSFECKVKHDHTLSLTVLWLKDNR 586
+ L + I P+++ +V+ G V ECK K T W K
Sbjct: 66 FSNAELSV-----IAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYT--WKKGRD 118
Query: 587 ELPSDERFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYD 645
L +ER T+ +D +L + +V+ D+G+YTC+A + S++ L V PT
Sbjct: 119 ILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPT-------R 171
Query: 646 VPNPPFDLELTDQLDKSVQLSWTPGDDNNSPI------TKFIIEYEDAMHKPGLWHHQTE 699
V PP +++T + +S+ L D++ I +I+++ + G H
Sbjct: 172 VMVPPSSMDVT--VGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFD----RDG--DHFER 223
Query: 700 VSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSL-PSEASEQYLTKASE-----PDKNPTAV 753
V G + L + R + + GK + + S L+ A++ P P AV
Sbjct: 224 VGGQDSAGDLMI--------RNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAV 275
Query: 754 EGLGSEPDNLVITWKPLNGFESNGPGLQY--------KVSWRQKDGDDEWTSVVVANVSK 805
++W+P G +++ P Y V W+ E ++
Sbjct: 276 TIDEITDTTAQLSWRP--GPDNHSPITMYVIQARTPFSVGWQAVSTVPE---LIDGKTFT 330
Query: 806 YIVSGTPTFVPYLIKVQALNDMGFA-PEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEV 864
V G +V Y + A N +G P + E LP V P NV + + +
Sbjct: 331 ATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVI 390
Query: 865 HWDPVPLKSIRGHLQGY--------RIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLP 916
W+ VP + G GY ++ + T +S R++ F+ H
Sbjct: 391 TWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYV------FRNESVH---- 440
Query: 917 GLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLE--WDP 974
PFS + + V V N KGEGP SP V + E P+ P + I +L + +E W
Sbjct: 441 ---PFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPA-SIFARSLSATDIEVFWAS 496
Query: 975 PSHPN-GILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTS 1033
P N G + Y +KY E ++ N+T + NL S Y A S
Sbjct: 497 PLEKNRGRIQGYEVKYWRHEDKEENAR--KIRTVGNQTSTKITNLKGSVLYHLAVKAYNS 554
Query: 1034 AGSGSQITEEAVTTVDEAGILPP 1056
AG+G VTT PP
Sbjct: 555 AGTGPSSATVNVTTRKPPPSQPP 577
Score = 71.6 bits (174), Expect = 5e-12
Identities = 55/180 (30%), Positives = 89/180 (49%), Gaps = 19/180 (10%)
Query: 62 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVT---MKPGTGTLIINIMSEGKAETYE 118
EN+ +C+A G+P P++ W +NG +PL+T ++ GTL I I++ A
Sbjct: 3 ENVFWECKANGRPKPTYKWLKNG-------EPLLTRDRIQIEQGTLNITIVNLSDA---- 51
Query: 119 GVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITL-QSGQSLVLPCRPPIGLPPPI 177
G+YQC A N+ G SN + + P +++ L+ +TL + G +V+ C+P P P+
Sbjct: 52 GMYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKAS-PKPV 110
Query: 178 IFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVK 237
W L ++ER++ +G+L NV D Y C A NH T + VK
Sbjct: 111 YTWKKGR-DILKENERITISEDGNLRIINVTKSDA-GSYTCIAT-NHFGTASSTGNLVVK 167
Score = 63.5 bits (153), Expect = 1e-09
Identities = 46/176 (26%), Positives = 81/176 (46%), Gaps = 7/176 (3%)
Query: 285 GNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKN 344
G + +EC + P P+ W K +L +N + + + L+II+V+++D+G+Y CIA N
Sbjct: 94 GGEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATN 153
Query: 345 ALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRI--SWLTNGVPIE 402
G T ++ VK + P ++ ++ GE L C+ + I +W NG I+
Sbjct: 154 HFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLID 213
Query: 403 IAPD-DPSRKIDGD----TIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP 453
D D ++ G ++ N+Q + + Y C L A A + V P
Sbjct: 214 FDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPP 269
Score = 59.3 bits (142), Expect = 2e-08
Identities = 53/196 (27%), Positives = 89/196 (45%), Gaps = 22/196 (11%)
Query: 291 ECIAEGLPTPIIYWAKE-DGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAI 349
EC A G P P W K + +L ++R + + TL I V+ +D+G YQC+A+N G I
Sbjct: 8 ECKANGRPKPTYKWLKNGEPLLTRDRIQIE--QGTLNITIVNLSDAGMYQCLAENKHGVI 65
Query: 350 --HHTISVRVKAAPYWITAPQNLVL-SPGEDGTLICRANGNPKPRISW------LTNGVP 400
+ +SV + T + + L G + + C+ +PKP +W L
Sbjct: 66 FSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKENER 125
Query: 401 IEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPA 460
I I+ D R I NV + + Y C A+N +G + + V+ +P R++ P
Sbjct: 126 ITISEDGNLRII--------NVTKSDAGSYTCIATNHFGTASSTGNL-VVKDPTRVMVPP 176
Query: 461 NTLYQVIANRPALLDC 476
+++ V +L C
Sbjct: 177 SSM-DVTVGESIVLPC 191
Score = 55.1 bits (131), Expect = 4e-07
Identities = 45/183 (24%), Positives = 79/183 (43%), Gaps = 6/183 (3%)
Query: 713 PYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITW-KPLN 771
P+ + +V N+ G+ S + Y + EP K P ++ ++ + W PL
Sbjct: 441 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAE-EEPTKPPASIFARSLSATDIEVFWASPLE 499
Query: 772 GFESNGPGLQYKVSWRQKDGDDEWTSV-VVANVSKYIVSGTPTFVPYLIKVQALNDMGFA 830
G + K WR +D ++ + V N + ++ V Y + V+A N G
Sbjct: 500 KNRGRIQGYEVKY-WRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTG 558
Query: 831 PEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYY-WKTQ 889
P A V + + P PGN+ N +S + ++WD V ++GY++ Y W Q
Sbjct: 559 PSSATVNVTTRKPPPSQPPGNIIWNSSDSKII-LNWDQVKALDNESEVKGYKVLYRWNRQ 617
Query: 890 SSS 892
SS+
Sbjct: 618 SST 620
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 264 bits (674), Expect = 5e-70
Identities = 257/1067 (24%), Positives = 439/1067 (41%), Gaps = 90/1067 (8%)
Query: 64 IVIQCEAKGKPPPSFSWTRNG---THFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 120
+V+ C A+G P F W N T F ++ ++T T+ G
Sbjct: 44 LVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSLD---------------RTHAGF 88
Query: 121 YQCTARNERGAAVSNNIVVRPSRSPLWTK-EKLEPITLQSGQSLVLPCRPPIGLPPPIIF 179
Y+C RN GA + V+ + + + EK + ++ G++ V+ P P +
Sbjct: 89 YRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVS--HGEAAVIRAPRIASFPQPQVT 146
Query: 180 WMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVI 239
W + +++P S R++ L L + + D Y+ + + QPI++ V
Sbjct: 147 WFRDG-RKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDN-KTSQPITLTVE 204
Query: 240 SVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPT 299
+V D IA PT + P N S + ++LEC+A P
Sbjct: 205 NVGGPADPIA------------------PTIIIPPKNTSVVAGT--SEVTLECVANARPL 244
Query: 300 PIIY--WAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIA---KNALGAIHHTIS 354
++ W K+DG+L N + L I + + +D+G Y+C A +++ ++
Sbjct: 245 IKLHIIW-KKDGVLLSGGISDHN--RRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAY 301
Query: 355 VRVKAAPYWITAPQNLVLSPGEDGTLI-CRANGNPKPRISWLTNGVPIEIAPDDPSRKID 413
+ V P ++ P+ + + E I C+A G P P I+W + +E+ R+ +
Sbjct: 302 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRN 361
Query: 414 GDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPAL 473
+ S + + ++QC A N G + + ++ V + P I T VI +
Sbjct: 362 DGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNI-TRGPLDSTVIDGMSVV 420
Query: 474 LDCAFFGSPLPTIEWFKGAK---GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNK 530
L C G+P P I W KG + ++ + E+G+L I GTYTC+A N
Sbjct: 421 LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNS 480
Query: 531 LGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPS 590
G+ + L + T I K P+ V +G+ S C V HD +++ +W KD L +
Sbjct: 481 RGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT 540
Query: 591 DE--RFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVP 647
+ R +D++ L ++ D GTYTC + + S SA L V P
Sbjct: 541 ESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPE------ 594
Query: 648 NPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTA 707
+P L ++ +++ L+WT D NSP+ ++I+E + + + T T
Sbjct: 595 HPVATLSTVER--RAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTV 652
Query: 708 QLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITW 767
+ L P +Y FR+ AVN +GK S+ +E+ P P V G +++I W
Sbjct: 653 K-GLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQW 711
Query: 768 KPLNGFESNG--PGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALN 825
+P NG G + ++ ++ A+V+ ++ + Y I+V A N
Sbjct: 712 QPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYN 771
Query: 826 DMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYY 885
G + V + + +P V PGNV NST W+ + I G QGY++
Sbjct: 772 SAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIA 831
Query: 886 WKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVF 945
W+ + + FQ S G + GL+ F+ Y +V G+GP S ++
Sbjct: 832 WEPEQEEEVTMVTARPN---FQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLV 888
Query: 946 NTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLK 1005
T E VP L SL + W P NGILT Y + ++ N T+ V
Sbjct: 889 RTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTN---TRVTHY 945
Query: 1006 IPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQA 1065
+P + + L T Y A TS G G Q++ +++ + P G +
Sbjct: 946 LPNVTLEYRVTGLTALTTYTIEVAAMTSKGQG-QVSASTISSGVPPELPGPPTNLG-ISN 1003
Query: 1066 VNPRISNLTAAAAETYANISWEYEGPEHVNFYV---EYGVAGSKEEW 1109
+ PR L Y+G ++ ++ + GV G EEW
Sbjct: 1004 IGPRSVTLQFRPG---------YDGKTSISRWLVEAQVGVVGEGEEW 1041
Score = 203 bits (516), Expect = 1e-51
Identities = 166/591 (28%), Positives = 259/591 (43%), Gaps = 59/591 (9%)
Query: 645 DVPNPPFD--LELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWH-HQTEVS 701
D P PP ++ D +SV LSW PG D SP+ + I+ + G W H VS
Sbjct: 1398 DRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTREL--PSGRWALHSASVS 1455
Query: 702 GTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEP 760
++ + +L P+ +Y FRV A N IG S SE SE T + PD+ PT +
Sbjct: 1456 HNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTT 1515
Query: 761 DNLVITWKPLNGFESNGPGLQYKVSWRQ--------------KDGDDEWTSVV----VAN 802
+++I W+P + NG L +++ +R+ + W + + N
Sbjct: 1516 TSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRN 1575
Query: 803 VSK-----YIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVV 857
+S+ Y + Y I++ N +G P GE +P AP NV V+
Sbjct: 1576 LSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGA 1635
Query: 858 NSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPG 917
+T +V W+P PL S G +QGY+IY+W+ Q R ++ +++ T ++ L
Sbjct: 1636 TATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQ------RGNLTERVKTLFLAENSVKLKN 1689
Query: 918 LEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSH 977
L ++ Y ++V N G+GP S T + PSAPSS+K T S+ + W+ P
Sbjct: 1690 LTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQF 1749
Query: 978 PNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRW-TLKNLNFSTRYKFYFYAQTSAGS 1036
PNGIL Y L Y+P + + +V + + N W +K+L Y+F A+T
Sbjct: 1750 PNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFT-Y 1808
Query: 1037 GSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISWEYEGPEH--V 1094
G +I T E PP V P I ++A A I W P +
Sbjct: 1809 GPEIEANVTTGPGEGAPGPPGV---------PIIVRYSSAIA-----IHWSSGDPGKGPI 1854
Query: 1095 NFYVEYGVAGSKEEWR---KEIVNGSRSF-FGLKGLMPGTAYKVRVGAVGDSGFVSSEDV 1150
YV + W K+I S+ F + L PG +Y RV AV D GF +
Sbjct: 1855 TRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSP 1914
Query: 1151 FETGPAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVK 1201
++ PA + + WF+ ++ V L+ ++LL+ I R + KY K
Sbjct: 1915 SQSVPAQKAN--PFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKK 1963
Score = 166 bits (420), Expect = 1e-40
Identities = 147/545 (26%), Positives = 232/545 (42%), Gaps = 43/545 (7%)
Query: 625 VSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEY 684
VSAS + S V P ++P PP +L +++ +SV L + PG D + I+++++E
Sbjct: 979 VSASTISSGVPP--------ELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEA 1030
Query: 685 EDAMHKPG----LWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYL 740
+ + G L H + ++ L+P+ YSFR+ VN +G S PS+ S +
Sbjct: 1031 QVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQ 1090
Query: 741 TKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNG--PGLQYKVSWRQKDGDDEWTSV 798
T + PD P V + +L + W PL E NG + YK+ + + DG + S
Sbjct: 1091 TLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSH 1150
Query: 799 VVANVSK--YIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNV 856
VV + + Y + + Y ++VQA N +G P V+G + E +P P NV
Sbjct: 1151 VVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALA 1210
Query: 857 VNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLP 916
S+ V W VP G + GY++ Y + S ++ +E S L
Sbjct: 1211 TTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVE------GNSSRSAQLT 1264
Query: 917 GLEPFSHYTLNVRVVNGKGEG-PASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPP 975
GL + Y + V G+G P+ P + T + VP P + S+ L W PP
Sbjct: 1265 GLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPP 1324
Query: 976 SHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAG 1035
+ PNGI+ Y + ++ +N+T V++ P+ + ++T L + Y F AQT G
Sbjct: 1325 AAPNGIILAYQITHR-LNTTTANTATVEVLAPSAR-QYTATGLKPESVYLFRITAQTRKG 1382
Query: 1036 SGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISWE--YEGPEH 1093
G VTT PP P + A +SWE +G
Sbjct: 1383 WGEAAEALVVTTEKRDRPQPPS---------RPMVQQEDVRARSVL--LSWEPGSDGLSP 1431
Query: 1094 VNFYVEYGVAGSKEEW--RKEIVNGSRSFFGLKGLMPGTAYKVRVGA---VGDSGFVSSE 1148
V +Y W V+ + S F + L P T+YK RV A +GDS F
Sbjct: 1432 VRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEES 1491
Query: 1149 DVFET 1153
+ T
Sbjct: 1492 ESLTT 1496
Score = 79.7 bits (195), Expect = 2e-14
Identities = 101/386 (26%), Positives = 151/386 (39%), Gaps = 40/386 (10%)
Query: 283 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK-NFEKTLQIIHVSEADSGNYQCI 341
L GN L L C+AEG W E L NR + K + E I + +G Y+CI
Sbjct: 39 LEGNRLVLTCMAEG------SWPLEFKWLHNNRELTKFSLEYRYMITSLDRTHAGFYRCI 92
Query: 342 AKNALGA-IHHTISVRVKAAPYWITAPQNLVLSPGEDGTLIC-RANGNPKPRISWLTNGV 399
+N +GA + V+V + ++ +S GE + R P+P+++W +G
Sbjct: 93 VRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGR 152
Query: 400 PIEIAPDDPSRKI----DGDTIIFSNVQERS-----SAVYQCNASNEYGYLLANAFVNV- 449
I PS +I + +I S V + AV N N+ + NV
Sbjct: 153 KI-----PPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVG 207
Query: 450 -LAEP--PRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE 506
A+P P I+ P V L+C PL + G L I
Sbjct: 208 GPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGI--SDH 265
Query: 507 NGTLEIPVAQKDSTGTYTCVARNKLGMAKNEV---HLEIKDPTWIVKQPE-YAVVQRGSM 562
N L IP G Y C A + + V +L + +P VK+PE + + +
Sbjct: 266 NRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKV 325
Query: 563 VSFECKVKHDHTLSLTVLWLKDNR--ELPSDERFTVDKD-HLVVADVSDDDSGTYTCVAN 619
V C+ K S+T W KD E+ RF D L ++ + DD+G + C A
Sbjct: 326 VDIPCQAKGVPPPSIT--WYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFAR 383
Query: 620 TTLDSVSASAVLSV--VAPTPTPAPV 643
V S L+V +AP T P+
Sbjct: 384 NAAGEVQTSTYLAVTSIAPNITRGPL 409
Score = 61.6 bits (148), Expect = 5e-09
Identities = 41/140 (29%), Positives = 70/140 (50%), Gaps = 9/140 (6%)
Query: 42 LVQPPTITQQSPKDYIIDPRENIV-IQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPG 100
+++PP ++ P+ +I E +V I C+AKG PPPS +W ++ +++K +
Sbjct: 304 VLEPPQFVKE-PERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRND 362
Query: 101 TGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSG 160
G I ++ + G++QC ARN G ++ + S +P T+ L+ T+ G
Sbjct: 363 GGLQISGLVPDD-----TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDS-TVIDG 416
Query: 161 QSLVLPCRPPIGLPPPIIFW 180
S+VL C G P P I W
Sbjct: 417 MSVVLACETS-GAPRPAITW 435
Score = 35.4 bits (80), Expect = 0.36
Identities = 37/167 (22%), Positives = 65/167 (38%), Gaps = 6/167 (3%)
Query: 46 PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKP-GTGTL 104
P IT+ P D + ++V+ CE G P P+ +W + L P +G+L
Sbjct: 402 PNITR-GPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSL 460
Query: 105 IINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLV 164
+I+ A G Y C A N RG ++ +V +R+ + + + + + S+V
Sbjct: 461 LISPTHISDA----GTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMV 516
Query: 165 LPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPED 211
+ I+ D + R+ NG L+ S D
Sbjct: 517 CGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGD 563
>gi|157311649 neogenin homolog 1 [Homo sapiens]
Length = 1461
Score = 229 bits (583), Expect = 2e-59
Identities = 218/803 (27%), Positives = 344/803 (42%), Gaps = 79/803 (9%)
Query: 283 LRGNVLSLECIAEGLPTPIIYWAKEDG------------MLPKNRTVYKNFEKTLQIIHV 330
+RG+ + L C A P+P I W K+DG +LP N ++H
Sbjct: 65 VRGSSVILNCSAYSEPSPKIEW-KKDGTFLNLVSDDRRQLLPDGSLFISN------VVHS 117
Query: 331 --SEADSGNYQCIAK-NALGA-IHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANG 386
++ D G YQC+A +LG I T + V P + + P+ + G + L C N
Sbjct: 118 KHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNCEVNA 177
Query: 387 NPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAF 446
+ P + W N P+ + DD K+ ++ SN E +Y+C + ++
Sbjct: 178 DLVPFVRWEQNRQPLLL--DDRVIKLPSGMLVISNATEGDGGLYRCVVESGGPPKYSDEV 235
Query: 447 -VNVLAEPPRI-----LTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKG-SALHE 499
+ VL +P I L + L +VI + +L C G P PTI+W K +
Sbjct: 236 ELKVLPDPEVISDLVFLKQPSPLVRVI-GQDVVLPCVASGLPTPTIKWMKNEEALDTESS 294
Query: 500 DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 559
+ VL G+LEI +D GTY C+A N + + L ++ +KQP
Sbjct: 295 ERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHE 354
Query: 560 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVA 618
+ FEC+V T TV W+K+ + + F + K+H L V + D G Y C+A
Sbjct: 355 SMDIVFECEVTGKPT--PTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIA 412
Query: 619 NTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSW-TPGDDNNSPI 677
+ + A A L ++ PA +P+ P D+ + + ++L+W TP D +
Sbjct: 413 ENDVGNAQAGAQLIIL--EHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDN 470
Query: 678 TKFIIEYEDAMHKPGLWHHQTEVSG----TQTTAQLKLSPYVNYSFRVMAVNSIG---KS 730
+ + Y K G+ + E + Q T Q L P Y FRVMA N G S
Sbjct: 471 LTYSVFYT----KEGIARERVENTSHPGEMQVTIQ-NLMPATVYIFRVMAQNKHGSGESS 525
Query: 731 LPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWK-PLNGFESNGPGLQYKVSWRQK 789
P Q + P N + + P ++ +TW+ P++G NG YK+ + +K
Sbjct: 526 APLRVETQPEVQLPGPAPN---LRAYAASPTSITVTWETPVSG---NGEIQNYKLYYMEK 579
Query: 790 DGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAP 849
G D+ V V++ S Y ++G + Y +V A N G V + D+P AP
Sbjct: 580 -GTDKEQDVDVSSHS-YTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAP 637
Query: 850 GNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGS 909
N+ + V NS +HW P + G + GY+I Y K S + G+
Sbjct: 638 QNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKASRKSDVTETLV-------SGT 690
Query: 910 KTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEG------VPSAPSSLKIVNP 963
+ ++ GL+ + Y V + G GPA+ T E VP PSSL V P
Sbjct: 691 QLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLH-VRP 749
Query: 964 TLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTR 1023
+ S+ + W PP + N ++ Y + Y I S H VD K + +T++NL+ S+
Sbjct: 750 LVTSIVVSWTPPENQNIVVRGYAIGY-GIGSPHAQTIKVDYK----QRYYTIENLDPSSH 804
Query: 1024 YKFYFYAQTSAGSGSQITEEAVT 1046
Y A + G G + E AVT
Sbjct: 805 YVITLKAFNNVGEGIPLYESAVT 827
Score = 177 bits (449), Expect = 6e-44
Identities = 245/1084 (22%), Positives = 406/1084 (37%), Gaps = 150/1084 (13%)
Query: 53 PKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEG 112
P D + ++++ C A +P P W ++GT ++ D + P I N++
Sbjct: 59 PVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSK 118
Query: 113 KAETYEGVYQCTARNER-GAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPI 171
+ EG YQC A E G +S + + P +T + EP ++ +G + +L C
Sbjct: 119 HNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQP-EPSSVYAGNNAILNCEVNA 177
Query: 172 GLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQK 231
L P + W N Q L +RV + +G L SN D Y C +
Sbjct: 178 DLVP-FVRWEQNR-QPLLLDDRVIKLPSGMLVISNATEGDGGL-YRCVVESGGPPKYSDE 234
Query: 232 QPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLE 291
+ +KV+ E+ +SD F S R + G + L
Sbjct: 235 --VELKVLPDPEV-------ISDLVFLKQPSPLVR----------------VIGQDVVLP 269
Query: 292 CIAEGLPTPIIYWAKEDGMLP--KNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAI 349
C+A GLPTP I W K + L + + +L+I V+E D+G Y CIA N I
Sbjct: 270 CVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETI 329
Query: 350 HHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPS 409
+ V+A P ++ P N+ D C G P P + W+ NG + P D
Sbjct: 330 EAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMV--IPSDYF 387
Query: 410 RKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIAN 469
+ + + + + YQC A N+ G A A + +L P P + +
Sbjct: 388 KIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGP-------LPS 440
Query: 470 RPALLDCAFFGSPLPTIEWFKGAK---GSALHEDIYVLHEN------------GTLEIPV 514
P + + + + W A G L ++ E G +++ +
Sbjct: 441 APRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTI 500
Query: 515 AQKDSTGTYT--CVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHD 572
Y +A+NK G ++ L ++ V+ P A R S
Sbjct: 501 QNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPE-VQLPGPAPNLRAYAAS-------- 551
Query: 573 HTLSLTVLW---LKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASA 629
S+TV W + N E+ + + + ++K DV D S +YT S
Sbjct: 552 -PTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDV-DVSSHSYTINGLKKYTEYSFRV 609
Query: 630 VL------SVVAPTPTPAPVYDVPNP-PFDLELTDQLDKSVQLSWTPGDD--NNSPITKF 680
V V P + DVP+ P +L L + KS+ + W P N IT +
Sbjct: 610 VAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGY 669
Query: 681 IIEYEDAMHKPGLWHHQTEVSGTQTTAQLK-LSPYVNYSFRVMA--VNSIGKSLPSEASE 737
I Y A K + +T VSGTQ + ++ L Y+FRV A +N G + ++E
Sbjct: 670 KIRYRKASRKSDVT--ETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAE 727
Query: 738 QYLTKASEPDKNPTAVEGLGSEP--DNLVITWKPLN-----------GFESNGPGLQ-YK 783
+ + E + P L P ++V++W P G+ P Q K
Sbjct: 728 TFESDLDET-RVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIK 786
Query: 784 VSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAP---EPAVVMGHS 840
V ++Q+ Y + Y+I ++A N++G E AV H+
Sbjct: 787 VDYKQR---------------YYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHT 831
Query: 841 G-----------------EDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQG-YR 882
+ PM+ P V+ ++++ + W L + Y
Sbjct: 832 DTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYY 891
Query: 883 IYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPD 942
WKT + ++ L++ ++ GL+P + Y +V V G+ S
Sbjct: 892 TVRWKTNIPANTKYKNANATTLSY-------LVTGLKPNTLYEFSVMVTKGRRSSTWSMT 944
Query: 943 RVFNTPEGVP-SAPSSLKIVNPTLDSLTL--EWDPPSHPNGILTEYTLKYQPINSTHELG 999
T E VP S P + +V+ T+ W PPS NG +T Y + Y + E+
Sbjct: 945 AHGTTFELVPTSPPKDVTVVSKEGKPKTIIVNWQPPSEANGKITGYII-YYSTDVNAEIH 1003
Query: 1000 PLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSG--SQITEEAVTTVDEAGILPPD 1057
V + N+ ++ L T Y F A+ S G G S+ + D + +P D
Sbjct: 1004 DWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKADSSDKMPND 1063
Query: 1058 VGAG 1061
+G
Sbjct: 1064 QASG 1067
Score = 142 bits (359), Expect = 2e-33
Identities = 189/833 (22%), Positives = 333/833 (39%), Gaps = 105/833 (12%)
Query: 354 SVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKID 413
S+R Y++ P + + G L C A P P+I W +G + + DD + +
Sbjct: 46 SIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLP 105
Query: 414 GDTIIFSNV-----QERSSAVYQCNASNE-YGYLLANAFVNVLAEPPRILTPANTLYQVI 467
++ SNV + YQC A+ E G +++ ++A PR T V
Sbjct: 106 DGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPR-FTSQPEPSSVY 164
Query: 468 ANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVA 527
A A+L+C +P + W + + L + + L +G L I A + G Y CV
Sbjct: 165 AGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKL-PSGMLVISNATEGDGGLYRCVV 223
Query: 528 RNKLGMAKNEVHLEIK---DPTWI-----VKQPEYAVVQRGSMVSFECKVKHDHTLSLTV 579
+ G K +E+K DP I +KQP V G V C T T+
Sbjct: 224 ESG-GPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPT--PTI 280
Query: 580 LWLKDNREL--PSDERFT-VDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVA- 635
W+K+ L S ER + L ++DV++DD+GTY C+A+ +++ A A L+V A
Sbjct: 281 KWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQ 340
Query: 636 ----PTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKP 691
PT ++ + F+ E+T + +V+ W D P F I E
Sbjct: 341 PEFLKQPTNIYAHESMDIVFECEVTGKPTPTVK--WVKNGDMVIPSDYFKIVKE------ 392
Query: 692 GLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPT 751
H +V G + + ++ +A N +G ++A Q + + P
Sbjct: 393 ----HNLQVLGLVKSDE--------GFYQCIAENDVGN---AQAGAQLIIL----EHAPA 433
Query: 752 AVEGLGSEPDNLV----------ITWKPLNGFESNGPGLQYKVSWRQKD-GDDEWTSVVV 800
L S P ++V +TW+ + +G L Y V + ++ + +
Sbjct: 434 TTGPLPSAPRDVVASLVSTRFIKLTWR-TPASDPHGDNLTYSVFYTKEGIARERVENTSH 492
Query: 801 ANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPG-NVRVNVVNS 859
+ + Y+ +V A N G A + + ++ + P N+R +
Sbjct: 493 PGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASP 552
Query: 860 TLAEVHWD-PVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGL 918
T V W+ PV S G +Q Y++YY + + +++ S + GL
Sbjct: 553 TSITVTWETPV---SGNGEIQNYKLYYMEKGTDKEQD----------VDVSSHSYTINGL 599
Query: 919 EPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPS-APSSLKIVNPTLDSLTLEWDP--P 975
+ ++ Y+ V N G G ++PD T VPS AP +L + S+ + W P P
Sbjct: 600 KKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAP 659
Query: 976 SHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAG 1035
+ NG +T Y ++Y+ + + + + + + ++ L+ T Y F A T G
Sbjct: 660 ATQNGQITGYKIRYRKASRKSD---VTETLVSGTQLSQLIEGLDRGTEYNFRVAALTING 716
Query: 1036 SGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISWEYEGPEHVN 1095
+G + T + D+ +V V S+L T +SW PE+ N
Sbjct: 717 TGPATDWLSAETFES------DLDETRVPEVP---SSLHVRPLVTSIVVSW--TPPENQN 765
Query: 1096 FYVE-----YGVAGSKEEWRKEIVNGSRSFFGLKGLMPGTAYKVRVGAVGDSG 1143
V YG+ + K V+ + ++ ++ L P + Y + + A + G
Sbjct: 766 IVVRGYAIGYGIGSPHAQTIK--VDYKQRYYTIENLDPSSHYVITLKAFNNVG 816
Score = 48.5 bits (114), Expect = 4e-05
Identities = 42/160 (26%), Positives = 69/160 (43%), Gaps = 13/160 (8%)
Query: 30 LEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDI 89
L+V DP+++ DLV + Q SP +I +++V+ C A G P P+ W +N D
Sbjct: 237 LKVLPDPEVISDLV---FLKQPSPLVRVIG--QDVVLPCVASGLPTPTIKWMKNEEALDT 291
Query: 90 DKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTK 149
+ + + G G+L I+ ++E A G Y C A N + + P + K
Sbjct: 292 ESSERLVLLAG-GSLEISDVTEDDA----GTYFCIADN-GNETIEAQAELTVQAQPEFLK 345
Query: 150 EKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLP 189
+ I +V C G P P + W+ N +P
Sbjct: 346 QPTN-IYAHESMDIVFECE-VTGKPTPTVKWVKNGDMVIP 383
Score = 43.9 bits (102), Expect = 0.001
Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 14/108 (12%)
Query: 48 ITQQSPKDYIIDPRE-------NIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPG 100
+T Q+ +++ P +IV +CE GKP P+ W +NG I D +K
Sbjct: 335 LTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNG-DMVIPSDYFKIVKEH 393
Query: 101 TGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWT 148
N+ G ++ EG YQC A N+ G A + ++ +P T
Sbjct: 394 ------NLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATT 435
Score = 40.8 bits (94), Expect = 0.009
Identities = 55/205 (26%), Positives = 81/205 (39%), Gaps = 23/205 (11%)
Query: 951 VPSAPSSLKIVNPTLDSLTLEW-DPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPAN 1009
+PSAP + + + L W P S P+G Y++ Y E V+
Sbjct: 438 LPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARER---VENTSHPG 494
Query: 1010 KTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPR 1069
+ + T++NL +T Y F AQ GSG V T E VQ P
Sbjct: 495 EMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPE------------VQLPGPA 542
Query: 1070 ISNLTAAAAETYANISWEYE---GPEHVNFYVEYGVAGSKEEWRKEIVNGSRSFFGLKGL 1126
+ AA+ T ++WE E N+ + Y G+ +E + V+ S + + GL
Sbjct: 543 PNLRAYAASPTSITVTWETPVSGNGEIQNYKLYYMEKGTDKE---QDVDVSSHSYTINGL 599
Query: 1127 MPGTAYKVRVGAVGDSG-FVSSEDV 1150
T Y RV A G VS+ DV
Sbjct: 600 KKYTEYSFRVVAYNKHGPGVSTPDV 624
>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
sapiens]
Length = 2113
Score = 224 bits (571), Expect = 4e-58
Identities = 259/1064 (24%), Positives = 419/1064 (39%), Gaps = 128/1064 (12%)
Query: 42 LVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGT 101
+V P +PK +++ C G P + W RN T + + +
Sbjct: 370 MVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRN-TELVLPDEAISIRGLSN 428
Query: 102 GTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ 161
TL+I +++ G YQC A + A I+ +P E + + G+
Sbjct: 429 ETLLIT----SAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKV-VNPGE 483
Query: 162 SLVLPCRPPIGLPPPIIFW-MDNSFQRLPQSERVSQGLNGD---LYFSNVLPEDTRED-- 215
L C G PPP + W +D+ S R +Q D + NV R+
Sbjct: 484 QFSLMCAAK-GAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGV 542
Query: 216 YICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEG 275
Y C AR NL + Y A+ + PP+
Sbjct: 543 YRCTAR-----------------------------NLVGSAEYQARINVRGPPSIRAMR- 572
Query: 276 NASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKN--RTVYKNFEKTLQIIHVSEA 333
N + G + C G P I W K+ +LP N + V++N TL++ V +
Sbjct: 573 ---NITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFEN--GTLKLTDVQKG 627
Query: 334 -DSGNYQC-IAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLI---CRANGNP 388
D G Y C + +I ++ V VK P Q P G L+ C +
Sbjct: 628 MDEGEYLCSVLIQPQLSISQSVHVAVKVPPLI----QPFEFPPASIGQLLYIPCVVSSGD 683
Query: 389 KP-RISWLTNG-VPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAF 446
P RI+W +G V I + K ++ S+V + + Y C ASN +
Sbjct: 684 MPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQ 743
Query: 447 VNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE 506
+ V P ++ P N I + +L+C+ G P P + W K AKGS + + +
Sbjct: 744 LIVRVPPRFVVQPNNQ--DGIYGKAGVLNCSVDGYPPPKVMW-KHAKGSGNPQQYHPVPL 800
Query: 507 NGTLEI---------PVAQKDSTGTYTCVARNKLGM-AKNEVHLEIKDPTWIVKQPEYAV 556
G ++I V ++D G Y C A N +G + L +K P I P +
Sbjct: 801 TGRIQILPNSSLLIRHVLEED-IGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTTI 859
Query: 557 VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDE--RFTV-DKDH-------LVVADV 606
+G C + + + + W K + + D R+ + KD+ L +
Sbjct: 860 AIKGHAKELNCTARGERPI--IIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPA 917
Query: 607 SDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLS 666
DS ++C A + L+V P P+PP +LE+ + +S+ L
Sbjct: 918 DRGDSVFFSCHAINSYGEDRGLIQLTVQEP----------PDPP-ELEIREVKARSMNLR 966
Query: 667 WTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQL-KLSPYVNYSFRVMAVN 725
WT D NS IT F IEY++ +S T A + L P YS R+ + N
Sbjct: 967 WTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFN 1026
Query: 726 SIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVS 785
IG+S PS+ T+ + PD P V ++ +TWK NG Y++
Sbjct: 1027 KIGRSEPSKELT-ISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIG 1085
Query: 786 WRQKD-GDDEWTSVV----VANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHS 840
+R+ G + S+V + Y + F Y + VQA N G P + + +
Sbjct: 1086 YRENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATT 1145
Query: 841 GEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIE 900
ED+P P NVR + S +A + W P ++ G L+GYR+ +W + E
Sbjct: 1146 LEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWG----E 1201
Query: 901 KKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKI 960
+ +T + L G+E F++Y++ V G+G S T E VP P+ +K
Sbjct: 1202 MQNITTTRERVE--LRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKA 1259
Query: 961 VNPTLDSLTLEWDPPSHPNGILTEYTL------KYQPINSTHELGPLVDLKIPANKTRWT 1014
V + S+ + W PP+ PNG++ +YT+ QP S +E P + +
Sbjct: 1260 VPSSASSVVVSWLPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSP--------EQLFYR 1311
Query: 1015 LKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDV 1058
+ +LN +Y + A TSAG G+ + T++ AG P +
Sbjct: 1312 IAHLNRGQQYLLWVAAVTSAGRGNSSEK---VTIEPAGKAPAKI 1352
Score = 166 bits (421), Expect = 1e-40
Identities = 264/1156 (22%), Positives = 434/1156 (37%), Gaps = 162/1156 (14%)
Query: 57 IIDPRENIVIQCEAKGKPPPSFSWT-------RNGTHFDIDKDPLVTMKPGTGTLIINIM 109
+++P E + C AKG PPP+ +W R+G+H + TM GT +N+
Sbjct: 478 VVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSH----RTNQYTMSDGTTISHMNVT 533
Query: 110 SEGKAETYEGVYQCTARNERGAA-VSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCR 168
G GVY+CTARN G+A I VR S + IT +G+ ++ CR
Sbjct: 534 --GPQIRDGGVYRCTARNLVGSAEYQARINVRGPPSI----RAMRNITAVAGRDTLINCR 587
Query: 169 PPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTI 228
IG P I W ++ LP + R NG L ++V +Y+C +I
Sbjct: 588 V-IGYPYYSIKWYKDALL-LPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSI 645
Query: 229 QQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVL 288
Q ++VKV + + EF PP + G +L
Sbjct: 646 SQSVHVAVKVPPL----------IQPFEF---------PPASI-------------GQLL 673
Query: 289 SLECIAEGLPTPI-IYWAKEDGMLPKNRTVY---KNFEKTLQIIHVSEADSGNYQCIAKN 344
+ C+ PI I W K+ ++ V K F +LQI VS +GNY CIA N
Sbjct: 674 YIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASN 733
Query: 345 ALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLT---NGVPI 401
A + + V+ P ++ P N G+ G L C +G P P++ W +G P
Sbjct: 734 AAATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQ 793
Query: 402 EIAPDDPSRKID---GDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILT 458
+ P + +I +++ +V E Y C ASN G ++ + + P I +
Sbjct: 794 QYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITS 853
Query: 459 PANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLH-----ENG----- 508
NT I L+C G I W KG + + D + + +NG
Sbjct: 854 HPNTTI-AIKGHAKELNCTARGERPIIIRWEKG--DTVIDPDRVMRYAIATKDNGDEVVS 910
Query: 509 TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQ-RGSMVSFEC 567
TL++ A + + ++C A N G + + L +++P PE + + + ++
Sbjct: 911 TLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPP---DPPELEIREVKARSMNLRW 967
Query: 568 KVKHDHTLSLTVLWLK--------DNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVAN 619
+ D +T ++ D ++ + T+++ ++V D+ + +
Sbjct: 968 TQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIV--DLHPASVYSIRMYSF 1025
Query: 620 TTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSW-TPGDD-NNSPI 677
+ S L++ P PP D+ L +S+Q++W P + N I
Sbjct: 1026 NKIGRSEPSKELTISTEEAAP------DGPPMDVTLQPVTSQSIQVTWKAPKKELQNGVI 1079
Query: 678 TKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQL---KLSPYVNYSFRVMAVNSIGKSLPSE 734
+ I Y + + E+ T + L + Y V A N G PS
Sbjct: 1080 RGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTG-PSS 1138
Query: 735 ASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDE 794
+ T P + P V L D VI+W NG Y+V + D E
Sbjct: 1139 SEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGE 1198
Query: 795 WTSV--VVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNV 852
W + + + + G F Y ++V A G +V+ + ED+P P +
Sbjct: 1199 WGEMQNITTTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPG-PPAGI 1257
Query: 853 RVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTH 912
+ +++ V W P P K G ++ Y I+ S + F
Sbjct: 1258 KAVPSSASSVVVSWLP-PTKP-NGVIRKYTIFCSSPGSGQPAPSEYETSPEQLFY----- 1310
Query: 913 GMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEW 972
+ L Y L V V G G +S ++V P G AP+ + T+ T W
Sbjct: 1311 -RIAHLNRGQQYLLWVAAVTSAGRGNSS-EKVTIEPAG--KAPAKIISFGGTV---TTPW 1363
Query: 973 DPPSHPNGILTEYTLKYQPINSTHELGPLV-------DLKIPANKTRWTLKNLNFSTRYK 1025
+ + L P NS + P V D IP + L + N + +
Sbjct: 1364 ---------MKDVRL---PCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLR 1411
Query: 1026 --------FYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRIS-NLTAA 1076
+Y T+ G I + V PPD PR++ + T+A
Sbjct: 1412 AVKAEDSGYYTCTATNTGGFDTIIVNLLVQV------PPD---------QPRLTVSKTSA 1456
Query: 1077 AAETYANISWEYEGPEHVNFYVEYGVAGSKEEWRKEIVNGSRSFFGLKGLMPGTAYKVRV 1136
++ T I + G F ++Y V S EEW+ ++ S F L L GT YKV++
Sbjct: 1457 SSITLTWIPGDNGGSSIRGFVLQYSVDNS-EEWKDVFISSSERSFKLDSLKCGTWYKVKL 1515
Query: 1137 GAVGDSGFVSSEDVFE 1152
A G ++ E
Sbjct: 1516 AAKNSVGSGRISEIIE 1531
Score = 123 bits (308), Expect = 1e-27
Identities = 148/590 (25%), Positives = 231/590 (39%), Gaps = 53/590 (8%)
Query: 64 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETY--EGVY 121
+V+ C A G P + W T DI P + GTL + S ++ + Y
Sbjct: 103 VVVPCPAAGSPSAALRWYL-ATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDNDY 161
Query: 122 QCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPP--PIIF 179
CTA N G S NI V+ +T ++E G V C P + ++
Sbjct: 162 FCTAENAAGKIRSPNIRVKAVFREPYTV-RVEDQRSMRGNVAVFKCLIPSSVQEYVSVVS 220
Query: 180 WMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVI 239
W ++ +P+ R +G LY S+V ED Y C + ++ +Q
Sbjct: 221 WEKDTVSIIPE-HRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSN------- 272
Query: 240 SVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPT 299
A LS T+ E PT L ++E G+ + L C A G P
Sbjct: 273 ---------GARLSVTD------PAESIPTILD---GFHSQEVWAGHTVELPCTASGYPI 314
Query: 300 PIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKA 359
P I W K+ LP + K L I + DSG Y C N G+ T + V
Sbjct: 315 PAIRWLKDGRPLPADSRWTKRITG-LTISDLRTEDSGTYICEVTNTFGSAEATGILMVID 373
Query: 360 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDD--PSRKIDGDTI 417
+ P+ L G L C G+P+ I W N + PD+ R + +T+
Sbjct: 374 PLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRN--TELVLPDEAISIRGLSNETL 431
Query: 418 IFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCA 477
+ ++ Q+ S YQC A+ + A + + PRI++ + V L CA
Sbjct: 432 LITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKV-VNPGEQFSLMCA 490
Query: 478 FFGSPLPTIEWFKG----AKGSALHEDIYVLHENGT---LEIPVAQKDSTGTYTCVARNK 530
G+P PT+ W + + + Y + + T + + Q G Y C ARN
Sbjct: 491 AKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNL 550
Query: 531 LGMAKNEVHLEIKDPTWI-VKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELP 589
+G A+ + + ++ P I + AV R ++++ C+V S + W KD LP
Sbjct: 551 VGSAEYQARINVRGPPSIRAMRNITAVAGRDTLIN--CRVIGYPYYS--IKWYKDALLLP 606
Query: 590 SDERFTV-DKDHLVVADVSDD-DSGTYTC-VANTTLDSVSASAVLSVVAP 636
+ R V + L + DV D G Y C V S+S S ++V P
Sbjct: 607 DNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVP 656
Score = 67.0 bits (162), Expect = 1e-10
Identities = 69/309 (22%), Positives = 115/309 (37%), Gaps = 22/309 (7%)
Query: 346 LGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLI-CRANGNPKPRISW-LTNGVPIEI 403
L ++H V + Y++ V G ++ C A G+P + W L G I
Sbjct: 70 LDSLHKARPEDVGTSLYFVNDSLQQVTFSSSVGVVVPCPAAGSPSAALRWYLATGDDIYD 129
Query: 404 APDDPSRKIDGDTIIFSNVQERSSAV-----YQCNASNEYGYLLA-NAFVNVLAEPPRIL 457
P +G ++ ++ Y C A N G + + N V + P +
Sbjct: 130 VPHIRHVHANGTLQLYPFSPSAFNSFIHDNDYFCTAENAAGKIRSPNIRVKAVFREPYTV 189
Query: 458 TPANTLYQVIANRPALLDCAFFGSP---LPTIEWFKGAKGSALHEDIYVLHENGTLEIPV 514
+ + + A+ C S + + W K ++ + G V
Sbjct: 190 RVEDQ--RSMRGNVAVFKCLIPSSVQEYVSVVSWEKDTVSIIPEHRFFITYHGGLYISDV 247
Query: 515 AQKDSTGTYTCVARNKLG---MAKNEVHLEIKDPT----WIVKQPEYAVVQRGSMVSFEC 567
++D+ TY C+ ++K N L + DP I+ V G V C
Sbjct: 248 QKEDALSTYRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPC 307
Query: 568 KVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSA 627
++ WLKD R LP+D R+T L ++D+ +DSGTY C T S A
Sbjct: 308 TASGYPIPAIR--WLKDGRPLPADSRWTKRITGLTISDLRTEDSGTYICEVTNTFGSAEA 365
Query: 628 SAVLSVVAP 636
+ +L V+ P
Sbjct: 366 TGILMVIDP 374
Score = 66.6 bits (161), Expect = 1e-10
Identities = 86/371 (23%), Positives = 142/371 (38%), Gaps = 33/371 (8%)
Query: 292 CIAEGLPTPIIYWAKEDGM----LPKNRTVYKNFEKTLQIIHVSEA------DSGNYQCI 341
C A G P+ + W G +P R V+ N TLQ+ S + +Y C
Sbjct: 107 CPAAGSPSAALRWYLATGDDIYDVPHIRHVHAN--GTLQLYPFSPSAFNSFIHDNDYFCT 164
Query: 342 AKNALGAIHHTISVRVKAA---PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLT-N 397
A+NA G I ++RVKA PY + + G C + + +S ++
Sbjct: 165 AENAAGKIRSP-NIRVKAVFREPYTVRVEDQRSMR-GNVAVFKCLIPSSVQEYVSVVSWE 222
Query: 398 GVPIEIAPDDPSRKIDGDTIIFSNVQERSS-AVYQCNASNEYG--YLLANAFVNVLAEP- 453
+ I P+ + S+VQ+ + + Y+C ++Y +N + +P
Sbjct: 223 KDTVSIIPEHRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTDPA 282
Query: 454 ---PRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTL 510
P IL ++ +V A L C G P+P I W K G L D L
Sbjct: 283 ESIPTILDGFHS-QEVWAGHTVELPCTASGYPIPAIRWLKD--GRPLPADSRWTKRITGL 339
Query: 511 EIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVK 570
I + + +GTY C N G A+ L + DP + P+ GS V C +
Sbjct: 340 TISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALT 399
Query: 571 HDHTLSLTVLWLKDNRELPSDERFTV---DKDHLVVADVSDDDSGTYTCVANTTLDSVSA 627
T+ W ++ + DE ++ + L++ SG Y C A +
Sbjct: 400 GSP--EFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQD 457
Query: 628 SAVLSVVAPTP 638
A++++ TP
Sbjct: 458 FAIIALEDGTP 468
Score = 46.6 bits (109), Expect = 2e-04
Identities = 61/280 (21%), Positives = 106/280 (37%), Gaps = 32/280 (11%)
Query: 579 VLWLKDNRE--LP---SDERFTVDKDHLVVADVSDDDSGTYTCVANTT--LDSVSASAVL 631
V W KD+ + +P R L++ V +DSG YTC A T D++ + ++
Sbjct: 1381 VKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLV 1440
Query: 632 SVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKP 691
V P L ++ S+ L+W PGD+ S I F+++Y ++
Sbjct: 1441 QVPPDQPR-------------LTVSKTSASSITLTWIPGDNGGSSIRGFVLQY--SVDNS 1485
Query: 692 GLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEP--DKN 749
W S ++ L Y ++ A NS+G SE E T EP K+
Sbjct: 1486 EEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEA-KTHGREPSFSKD 1544
Query: 750 PTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVS 809
+ S L L G+ + G + V + G W + + + ++
Sbjct: 1545 QHLFTHINSTHARL-----NLQGWNNGGCPITAIVLEYRPKGTWAWQGLRANSSGEVFLT 1599
Query: 810 GTPTFVPYLIKVQALNDMGFAPEPA--VVMGHSGEDLPMV 847
Y ++++A N G E A + + G +P +
Sbjct: 1600 ELREATWYELRMRACNSAGCGNETAQFATLDYDGSTIPPI 1639
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 221 bits (564), Expect = 3e-57
Identities = 254/1030 (24%), Positives = 413/1030 (40%), Gaps = 102/1030 (9%)
Query: 43 VQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTG 102
V+ P SP+ + + C G SW RNG + K+ +T G
Sbjct: 310 VKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRIT-----G 364
Query: 103 TLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQS 162
N++ + ++ G YQC R ++ +A VV +P E + + +
Sbjct: 365 INHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKV-VSPAEP 423
Query: 163 LVLPCRPPIGLPPPIIFW-MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYAR 221
+ L C G P P I W +D+ S R+SQ + + NV + Y
Sbjct: 424 VSLMCNVK-GTPLPTITWTLDDDPILKGGSHRISQMITSE---GNV---------VSYLN 470
Query: 222 FNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKE 281
+ +Q + + A N + Y A+ + R P + P N +
Sbjct: 471 ISSSQ------------VRDGGVYRCTANNSAGVVLYQARIN-VRGPASIRPMKNIT--- 514
Query: 282 ELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKN-RTVYKNFEKTLQIIHVS-EADSGNYQ 339
+ G + C G P I W K +LP N R V TL++ V E D G Y
Sbjct: 515 AIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYT 574
Query: 340 C-IAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKP-RISWLTN 397
C + + ++ V VK P+ I + S G+ + C P I+W +
Sbjct: 575 CNVLVQPQLSTSQSVHVTVKVPPF-IQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKD 633
Query: 398 GVPIEIAPDDPSRKID-GDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI 456
G PI + ID ++ SN+ + Y C A NE + + + V P +
Sbjct: 634 GRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFV 693
Query: 457 LTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGS--------ALHEDIYVLHENG 508
+ P + I + +L+C+ G P+PTI W K +KG+ AL+ I VL NG
Sbjct: 694 VQPRDQ--DGIYGKAVILNCSAEGYPVPTIVW-KFSKGAGVPQFQPIALNGRIQVL-SNG 749
Query: 509 TLEIPVAQKDSTGTYTCVARNKLGM-AKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFEC 567
+L I ++ +G Y C N +G ++L +K P I P + +G C
Sbjct: 750 SLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKKEMSC 809
Query: 568 KVKHDHTLSLTVLWLKDNREL-PSDERFTVDKDH--------LVVADVSDDDSGTYTCVA 618
+ + V W K++R + P R+ V L + +DSG ++C A
Sbjct: 810 TAHGEKPI--IVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHA 867
Query: 619 NTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPIT 678
+ L+V P P+PP ++E+ D +++ L WT G D NSPIT
Sbjct: 868 INSYGEDRGIIQLTVQEP----------PDPP-EIEIKDVKARTITLRWTMGFDGNSPIT 916
Query: 679 KFIIEYEDAMHKPGLWHHQTEVSGTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSEASE 737
+ IE ++ +VS +A + + P YS R+ A N IGKS PS
Sbjct: 917 GYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELT 976
Query: 738 QYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQ-KDGDDEWT 796
+A+ PD P V ++ +TWK NG Y++ +R+ G +
Sbjct: 977 ITADEAA-PDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQF 1035
Query: 797 SVVVANVSK----YIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNV 852
+++ + S Y + F Y + VQA N G P ++ + ED+P P NV
Sbjct: 1036 NIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENV 1095
Query: 853 RVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTH 912
+ + + W + +++ G LQG+R+ YW + K I T Q S
Sbjct: 1096 QAIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGELGE---IKNITTTQPSLE- 1151
Query: 913 GMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEW 972
L GLE +++Y++ V G+G S T E VP P+ +K + + + W
Sbjct: 1152 --LDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSW 1209
Query: 973 DPPSHPNGILTEYTL----KYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYF 1028
PP NGI+ +YT+ Y + S E P + + + NL+ + +Y +
Sbjct: 1210 LPPLKLNGIIRKYTVFCSHPYPTVISEFEASP--------DSFSYRIPNLSRNRQYSVWV 1261
Query: 1029 YAQTSAGSGS 1038
A TSAG G+
Sbjct: 1262 VAVTSAGRGN 1271
Score = 112 bits (281), Expect = 2e-24
Identities = 141/597 (23%), Positives = 227/597 (38%), Gaps = 59/597 (9%)
Query: 40 EDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKP 99
EDL S ++ + ++ C A G PP + W T +I P +
Sbjct: 18 EDLHSSLYFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYL-ATGEEIYDVPGIRHVH 76
Query: 100 GTGTLIINIMSEGKAET--YEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITL 157
GTL I T ++ Y CTA N G S ++ ++ +T + T+
Sbjct: 77 PNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIRSQDVHIKAVLREPYTVRVEDQKTM 136
Query: 158 QSGQSLVLPCRPPIGLPP--PIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTRED 215
+ G V C P + ++ W ++ L R G LY +V ED +
Sbjct: 137 R-GNVAVFKCIIPSSVEAYITVVSWEKDTVS-LVSGSRFLITSTGALYIKDVQNEDGLYN 194
Query: 216 YICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEG 275
Y C R H T + +Q S ++ D N P+ L
Sbjct: 195 YRCITR--HRYTGETRQSNSARLFVSDPANSA--------------------PSILD--- 229
Query: 276 NASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT---LQIIHVSE 332
+++ + G + L C A G P P W K++ L + F+KT L I ++
Sbjct: 230 GFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSG----RFQKTVTGLLIENIRP 285
Query: 333 ADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRI 392
+DSG+Y C N G + VK +P+ + S G +L C G +
Sbjct: 286 SDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQEL 345
Query: 393 SWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE 452
SW NG + + I+ + +I ++ + YQC + L A +V V+ E
Sbjct: 346 SWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKD--KLSAQDYVQVVLE 403
Query: 453 --PPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKG----AKGSALHEDIYVLHE 506
P+I++ A + V P L C G+PLPTI W KG + H ++
Sbjct: 404 DGTPKIIS-AFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGS-HRISQMITS 461
Query: 507 NGT----LEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSM 562
G L I +Q G Y C A N G+ + + ++ P I + G
Sbjct: 462 EGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKNITAI-AGRD 520
Query: 563 VSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH--LVVADVSDD-DSGTYTC 616
C+V S + W K++ LP + R +++ L ++DV + D G YTC
Sbjct: 521 TYIHCRVIGYPYYS--IKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTC 575
Score = 61.6 bits (148), Expect = 5e-09
Identities = 72/291 (24%), Positives = 117/291 (40%), Gaps = 35/291 (12%)
Query: 567 CKVKHDHTLSLTVLWLKDNRELPS-----DERFTVDKDHLVVADVSDDDSGTYTCVANTT 621
CK D S V W+KD+ PS R ++ V +DSG Y+C+AN
Sbjct: 1307 CKAVGDP--SPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNN 1364
Query: 622 LDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFI 681
S L V P P L ++ S+ LSW PGD+ S I +I
Sbjct: 1365 WGSDEIILNLQVQVPPDQPR-----------LTVSKTTSSSITLSWLPGDNGGSSIRGYI 1413
Query: 682 IEY-EDAMHKPGLWHHQTEVSGTQTTAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASE-Q 738
++Y ED + G + +S ++ + +L+ L Y F + A N +G SE E +
Sbjct: 1414 LQYSEDNSEQWGSF----PISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAK 1469
Query: 739 YLTKASEPDKNPTAVEGLGSEPDNL-VITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTS 797
L K + K + + L +I W + P + + +R G WT+
Sbjct: 1470 TLGKEPQFSKEQELFASINTTRVRLNLIGWN-----DGGCPITSFTLEYR-PFGTTVWTT 1523
Query: 798 VVVANVSK-YIVSGTPTFVPYLIKVQALNDMGFAPEPA--VVMGHSGEDLP 845
++SK YI+ Y ++++ N G A + A + + G +P
Sbjct: 1524 AQRTSLSKSYILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTIP 1574
Score = 54.3 bits (129), Expect = 7e-07
Identities = 115/533 (21%), Positives = 197/533 (36%), Gaps = 77/533 (14%)
Query: 645 DVPN-PPFDLELTDQLDKSVQLSWTPGDDN--NSPITKFIIEYEDAMHKPGLWHHQTEVS 701
DVP+ PP +++ +S+ +SW+ N + F + Y A G ++
Sbjct: 1086 DVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYW-ANLMDGELGEIKNIT 1144
Query: 702 GTQTTAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTA-VEGLGSE 759
TQ + +L L Y NYS +V+A G + SEQ T+ E P A V+ +
Sbjct: 1145 TTQPSLELDGLEKYTNYSIQVLAFTRAGDGV---RSEQIFTRTKEDVPGPPAGVKAAAAS 1201
Query: 760 PDNLVITWKP---LNGFESNGPGL---QYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPT 813
+ ++W P LNG Y + + + S + N+S+
Sbjct: 1202 ASMVFVSWLPPLKLNGIIRKYTVFCSHPYPTVISEFEASPDSFSYRIPNLSRNR------ 1255
Query: 814 FVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPM--VAPGNVRVNVVNSTLAEVHWDPV-- 869
Y + V A+ G G+S E + + +A R+ + T+ +
Sbjct: 1256 --QYSVWVVAVTSAG--------RGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVL 1305
Query: 870 PLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVR 929
P K++ + W S+ + ++T G ++ FS+ + +R
Sbjct: 1306 PCKAVGDPSPAVK---WMKDSNGTPS-------LVTIDGRRSI--------FSNGSFIIR 1347
Query: 930 VVNGKGEGP---------ASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNG 980
V + G S + + N VP L + T S+TL W P +
Sbjct: 1348 TVKAEDSGYYSCIANNNWGSDEIILNLQVQVPPDQPRLTVSKTTSSSITLSWLPGDNGGS 1407
Query: 981 ILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQI 1040
+ Y L+Y NS + G I ++ + L+NL T YKF AQ G G
Sbjct: 1408 SIRGYILQYSEDNS-EQWG---SFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPG--- 1460
Query: 1041 TEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISWEYEGPEHVNFYVEY 1100
++ + EA L + K Q + I N T I W G +F +EY
Sbjct: 1461 ---RISEIIEAKTLGKEPQFSKEQELFASI-NTTRVRLNL---IGWNDGGCPITSFTLEY 1513
Query: 1101 GVAGSKEEWRKEIVNGSRSFFGLKGLMPGTAYKVRVGAVGDSGFVSSEDVFET 1153
G+ + + S+S+ L L T Y++++ +G + F T
Sbjct: 1514 RPFGTTVWTTAQRTSLSKSYI-LYDLQEATWYELQMRVCNSAGCAEKQANFAT 1565
Score = 53.9 bits (128), Expect = 1e-06
Identities = 81/349 (23%), Positives = 131/349 (37%), Gaps = 69/349 (19%)
Query: 42 LVQPPTITQQSPKDYI-----IDPRE--------NIVIQCEA-KGKPPPSFSWTRNGTHF 87
LVQP T QS + I P E + I C G P + +W ++G
Sbjct: 578 LVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPI 637
Query: 88 DIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAV-SNNIVVRPSRSPL 146
+ T +L I+ +S + G Y C ARNE A + ++VR +
Sbjct: 638 PGSLGVTIDNIDFTSSLRISNLSL----MHNGNYTCIARNEAAAVEHQSQLIVRVPPKFV 693
Query: 147 WTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDN------SFQRLPQSERVSQGLNG 200
+ I G++++L C G P P I W + FQ + + R+ NG
Sbjct: 694 VQPRDQDGI---YGKAVILNCSAE-GYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNG 749
Query: 201 DLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGA 260
L +V+ ED+ Y+C ++++ + A++S + +
Sbjct: 750 SLLIKHVVEEDSGY-YLC------------------------KVSNDVGADVSKSMYLTV 784
Query: 261 KSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGM--------LP 312
K P +T N + + G + C A G I+ W KED + L
Sbjct: 785 KI-----PAMITSYPNTTLATQ--GQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLV 837
Query: 313 KNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAP 361
+ V + TLQI+ DSG + C A N+ G I + V+ P
Sbjct: 838 STKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPP 886
Score = 51.2 bits (121), Expect = 6e-06
Identities = 62/246 (25%), Positives = 99/246 (40%), Gaps = 26/246 (10%)
Query: 918 LEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNP-TLDSLTLEWDPPS 976
+ P S Y++ + N G+ S + E P P + P + S+ + W P
Sbjct: 950 IHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPK 1009
Query: 977 H--PNGILTEYTLKYQPINSTHELG-PLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTS 1033
NGI+ Y + Y+ ++ ++ + + +TL NLN T+Y A
Sbjct: 1010 KHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNR 1069
Query: 1034 AGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISWEYEGPEH 1093
AG+G E TT+++ PP+ VQA+ A + +ISW E
Sbjct: 1070 AGTGPSSQEIITTTLEDVPSYPPE----NVQAI---------ATSPESISISWSTLSKEA 1116
Query: 1094 VN-----FYVEYGVAGSKEEWRKEIVN--GSRSFFGLKGLMPGTAYKVRVGAVGDSG-FV 1145
+N F V Y A + EI N ++ L GL T Y ++V A +G V
Sbjct: 1117 LNGILQGFRVIYW-ANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGV 1175
Query: 1146 SSEDVF 1151
SE +F
Sbjct: 1176 RSEQIF 1181
Score = 50.1 bits (118), Expect = 1e-05
Identities = 78/351 (22%), Positives = 124/351 (35%), Gaps = 31/351 (8%)
Query: 341 IAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLI-CRANGNPKPRISW-LTNG 398
+A + + + S + ++ Y++ A V+ GTL+ C A G P + W L G
Sbjct: 4 LALSLFQSFANVFSEDLHSSLYFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYLATG 63
Query: 399 VPIEIAPDDPSRKIDGDTIIFSNVQERSSAV-----YQCNASNEYGYLLANA--FVNVLA 451
I P +G IF S + Y C A N G + + VL
Sbjct: 64 EEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIRSQDVHIKAVLR 123
Query: 452 EPPRILTPANTLYQVIANRPALLDCAFFGSP---LPTIEWFKGAKGSALHEDIYVLHENG 508
EP + + + A+ C S + + W K S + +++ G
Sbjct: 124 EPYTVRVEDQ---KTMRGNVAVFKCIIPSSVEAYITVVSWEKDTV-SLVSGSRFLITSTG 179
Query: 509 TLEIP-VAQKDSTGTYTCVARNKLG---MAKNEVHLEIKDPT----WIVKQPEYAVVQRG 560
L I V +D Y C+ R++ N L + DP I+ ++ G
Sbjct: 180 ALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAG 239
Query: 561 SMVSFECK-VKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVAN 619
V CK + H WLKDN L RF L++ ++ DSG+Y C +
Sbjct: 240 QRVELPCKALGHPEP---DYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYVCEVS 296
Query: 620 TTLDSVSASAVLSVVAP---TPTPAPVYDVPNPPFDLELTDQLDKSVQLSW 667
+ L V P T +P V L + + +LSW
Sbjct: 297 NRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSW 347
Score = 47.0 bits (110), Expect = 1e-04
Identities = 36/148 (24%), Positives = 61/148 (41%), Gaps = 13/148 (8%)
Query: 319 KNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDG 378
+N + ++ ++ V+ A GN I T+ KA +T + +D
Sbjct: 1253 RNRQYSVWVVAVTSAGRGNSSEII---------TVEPLAKAPARILTFSGTVTTPWMKDI 1303
Query: 379 TLICRANGNPKPRISWL--TNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASN 436
L C+A G+P P + W+ +NG P + D + I V+ S Y C A+N
Sbjct: 1304 VLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANN 1363
Query: 437 EYG--YLLANAFVNVLAEPPRILTPANT 462
+G ++ N V V + PR+ T
Sbjct: 1364 NWGSDEIILNLQVQVPPDQPRLTVSKTT 1391
Score = 42.7 bits (99), Expect = 0.002
Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 4/96 (4%)
Query: 453 PPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDI---YVLHENGT 509
P RILT + T+ + +L C G P P ++W K + G+ I + NG+
Sbjct: 1285 PARILTFSGTVTTPWM-KDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGS 1343
Query: 510 LEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDP 545
I + + +G Y+C+A N G + ++L+++ P
Sbjct: 1344 FIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVP 1379
Score = 39.3 bits (90), Expect = 0.025
Identities = 33/140 (23%), Positives = 59/140 (42%), Gaps = 16/140 (11%)
Query: 228 IQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNV 287
+ + + SV V++V T A + +E + + P LT G +
Sbjct: 1251 LSRNRQYSVWVVAV-----TSAGRGNSSEIITVEPLAKAPARILTFSGTVTTPWM---KD 1302
Query: 288 LSLECIAEGLPTPIIYWAKEDGMLPK------NRTVYKNFEKTLQIIHVSEADSGNYQCI 341
+ L C A G P+P + W K+ P R+++ N ++ + DSG Y CI
Sbjct: 1303 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAE--DSGYYSCI 1360
Query: 342 AKNALGAIHHTISVRVKAAP 361
A N G+ ++++V+ P
Sbjct: 1361 ANNNWGSDEIILNLQVQVPP 1380
Score = 32.3 bits (72), Expect = 3.0
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 11/95 (11%)
Query: 62 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIIN---IMSEGKAETYE 118
++IV+ C+A G P P+ W + D + P + G ++ N I+ KAE
Sbjct: 1301 KDIVLPCKAVGDPSPAVKWMK-----DSNGTPSLVTIDGRRSIFSNGSFIIRTVKAED-S 1354
Query: 119 GVYQCTARNERGA--AVSNNIVVRPSRSPLWTKEK 151
G Y C A N G+ + N V P P T K
Sbjct: 1355 GYYSCIANNNWGSDEIILNLQVQVPPDQPRLTVSK 1389
>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
Length = 1447
Score = 218 bits (555), Expect = 3e-56
Identities = 212/799 (26%), Positives = 331/799 (41%), Gaps = 61/799 (7%)
Query: 278 SNKEELRGNVLSLECIAEG-LPTPIIYWAKED-----GMLPKNRTVYKNFEKTLQIIHVS 331
S+ +RG + L+C AE P+I W K+ GM + + + I+H
Sbjct: 47 SDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSR 106
Query: 332 --EADSGNYQCIAK--NALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGN 387
+ D G YQC A ++ I T V V +++ +++ G+ L C G
Sbjct: 107 HHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGE 166
Query: 388 PKPRISWLTNGVPIEIAPDDPSRKI--DGDTIIFSNVQERSSAVYQCNASNEYGYLLAN- 444
P P I W N + P D SR + + S +Q +Y+C+A N N
Sbjct: 167 PMPTIHWQKNQQDLTPIPGD-SRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNE 225
Query: 445 AFVNVLAEPPR------ILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALH 498
A V +L++P + P+N + I + A+L+C G P P+ W +G + L
Sbjct: 226 AEVRILSDPGLHRQLYFLQRPSNVV--AIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLR 283
Query: 499 EDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQ 558
Y L L I D +G YTCV K L + P W + P
Sbjct: 284 SKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAY 343
Query: 559 RGSMVSFECKVKHDHTLSLTVLWLKD-NRELPSDERFTVDKDHLVVADVSDDDSGTYTCV 617
+ FEC V TV W+K+ + +PSD V +L + V D G Y CV
Sbjct: 344 ESMDIEFECTVSGKPV--PTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCV 401
Query: 618 ANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPI 677
A + SA L V P + V +P+ P D+ + V+LSW P + I
Sbjct: 402 AENEAGNAQTSAQLIVPKPAIPSSSV--LPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNI 459
Query: 678 TKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASE 737
F + + + T+ Q T L P Y+FRV+A N G P E+S
Sbjct: 460 QTFTVFFSREGDNRERALNTTQPGSLQLTVG-NLKPEAMYTFRVVAYNEWG---PGESS- 514
Query: 738 QYLTKASEPD-KNPTAVEGL---GSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDD 793
Q + A++P+ + P VE L + P +++ITW+P +NGP Y++ +
Sbjct: 515 QPIKVATQPELQVPGPVENLQAVSTSPTSILITWEP--PAYANGPVQGYRLFCTEVSTGK 572
Query: 794 EWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVR 853
E ++ V +S Y + G F Y ++ A N G + + D+P P NV
Sbjct: 573 E-QNIEVDGLS-YKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVS 630
Query: 854 VNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHG 913
+ VVNS +V W P P + G + GY+I + KT + T + +
Sbjct: 631 LEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEME---------TLEPNNLWY 681
Query: 914 MLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEG------VPSAPSSLKIVNPTLDS 967
+ GLE S Y+ V + G GP S TPE VP PSSL V P +
Sbjct: 682 LFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLH-VRPQTNC 740
Query: 968 LTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFY 1027
+ + W PP +PN ++ Y + Y + E +++ + + ++++ L S+ Y
Sbjct: 741 IIMSWTPPLNPNIVVRGYIIGYGVGSPYAE-----TVRVDSKQRYYSIERLESSSHYVIS 795
Query: 1028 FYAQTSAGSGSQITEEAVT 1046
A +AG G + E A T
Sbjct: 796 LKAFNNAGEGVPLYESATT 814
Score = 147 bits (371), Expect = 6e-35
Identities = 238/1066 (22%), Positives = 395/1066 (37%), Gaps = 161/1066 (15%)
Query: 53 PKDYIIDPRENIVIQCEAKG-KPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSE 111
P D + N+++ C A+ + P W ++G H + D LI NI+
Sbjct: 46 PSDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHS 105
Query: 112 GKAETYEGVYQCTAR-NERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPP 170
+ EG+YQC A + G+ +S V + PL + E +T G +++L C
Sbjct: 106 RHHKPDEGLYQCEASLGDSGSIISRTAKVAVA-GPLRFLSQTESVTAFMGDTVLLKCE-V 163
Query: 171 IGLPPPIIFWMDN--SFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTI 228
IG P P I W N +P RV +G L S + P D Y C AR
Sbjct: 164 IGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDI-GIYRCSAR------- 215
Query: 229 QQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVL 288
P S + N+ LSD + +RP SN + G
Sbjct: 216 ---NPASSRT-----GNEAEVRILSDPGLHRQLYFLQRP----------SNVVAIEGKDA 257
Query: 289 SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNF-EKTLQIIHVSEADSGNYQCIAKNALG 347
LEC G P P W + + ++ Y L I +V++ DSG Y C+
Sbjct: 258 VLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNE 317
Query: 348 AIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDD 407
I + + V P+++ P NL D C +G P P ++W+ NG + P D
Sbjct: 318 NISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNG--DVVIPSD 375
Query: 408 PSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVI 467
+ + G + V + YQC A NE G NA + P+ P+++ V+
Sbjct: 376 YFQIVGGSNLRILGVVKSDEGFYQCVAENEAG----NAQTSAQLIVPKPAIPSSS---VL 428
Query: 468 ANRPALLDCAFFGSPLPTIEWF--KGAKGSALHEDIYVLHEN------------GTLEIP 513
+ P + S + W AKG+ ++ E G+L++
Sbjct: 429 PSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLT 488
Query: 514 VA--QKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAV---VQRGSMVSFECK 568
V + ++ T+ VA N+ G E P + QPE V V+ VS
Sbjct: 489 VGNLKPEAMYTFRVVAYNEWGPG------ESSQPIKVATQPELQVPGPVENLQAVS---- 538
Query: 569 VKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVS-------DDDSGTYTCVANTT 621
S+ + W E P+ V L +VS + D +Y
Sbjct: 539 ---TSPTSILITW-----EPPAYANGPVQGYRLFCTEVSTGKEQNIEVDGLSYKLEGLKK 590
Query: 622 LDSVSASAVL------SVVAPTPTPAPVYDVPN-PPFDLELTDQLDKSVQLSW--TPGDD 672
S + V T + DVP+ PP ++ L +S+++SW P
Sbjct: 591 FTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGT 650
Query: 673 NNSPITKFIIEYE--------DAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAV 724
N IT + I + + + LW+ T G + +Q YSF+V A+
Sbjct: 651 QNGFITGYKIRHRKTTRRGEMETLEPNNLWYLFT---GLEKGSQ--------YSFQVSAM 699
Query: 725 NSIGKSLPS-----EASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKP-------LNG 772
G PS E E L ++ PD+ P+++ + + + ++++W P + G
Sbjct: 700 TVNGTGPPSNWYTAETPENDLDESQVPDQ-PSSLH-VRPQTNCIIMSWTPPLNPNIVVRG 757
Query: 773 F-ESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVS---------GTPTFVPYLIK-- 820
+ G G Y + R ++ + + S Y++S G P + +
Sbjct: 758 YIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSI 817
Query: 821 VQALNDMGFAP----EPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHW--DPVPLKSI 874
+ + + P P V S PM+ P V+ + V W + VP
Sbjct: 818 TDPTDPVDYYPLLDDFPTSVPDLS---TPMLPPVGVQAVALTHDAVRVSWADNSVPKNQK 874
Query: 875 RGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGK 934
++ Y + W+T S+ + + L++ + GL+P + Y +V V +
Sbjct: 875 TSEVRLYTV-RWRTSFSASAKYKSEDTTSLSYTAT-------GLKPNTMYEFSVMVTKNR 926
Query: 935 GEGPASPDRVFNTPEGVP-SAPSSLKIV--NPTLDSLTLEWDPPSHPNGILTEYTLKYQP 991
S T E P SAP L ++ ++ + W PP NG +T Y L Y
Sbjct: 927 RSSTWSMTAHATTYEAAPTSAPKDLTVITREGKPRAVIVSWQPPLEANGKITAYILFY-T 985
Query: 992 INSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1037
++ + + I ++ + +LN T Y F A+ S G G
Sbjct: 986 LDKNIPIDDWIMETISGDRLTHQIMDLNLDTMYYFRIQARNSKGVG 1031
Score = 140 bits (354), Expect = 6e-33
Identities = 228/1060 (21%), Positives = 383/1060 (36%), Gaps = 141/1060 (13%)
Query: 150 EKLEPITLQSGQSLVLPCRPPIGLPPPIIFWM-DNSFQRLPQSERVSQGLNGDLYFSNVL 208
E + +T++ G +++L C P+I W D L ER Q NG L N+L
Sbjct: 45 EPSDAVTMRGG-NVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNIL 103
Query: 209 PEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPP 268
H++ + + + S+ + I+ AK + P
Sbjct: 104 ---------------HSRHHKPDEGLYQCEASLGDSGSIISRT--------AKVAVAGPL 140
Query: 269 TFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGML---PKNRTVYKNFEKTL 325
FL+ + + G+ + L+C G P P I+W K L P + V L
Sbjct: 141 RFLSQTESVT---AFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGAL 197
Query: 326 QIIHVSEADSGNYQCIAKN-ALGAIHHTISVRVKAAP------YWITAPQNLVLSPGEDG 378
QI + D G Y+C A+N A + VR+ + P Y++ P N+V G+D
Sbjct: 198 QISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDA 257
Query: 379 TLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEY 438
L C +G P P +WL I++ S + G ++ SNV + S +Y C + +
Sbjct: 258 VLECCVSGYPPPSFTWLRGEEVIQLRSKKYSL-LGGSNLLISNVTDDDSGMYTCVVTYKN 316
Query: 439 GYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALH 498
+ A+A + VL PP L + LY + +C G P+PT+ W K +
Sbjct: 317 ENISASAELTVLV-PPWFLNHPSNLY-AYESMDIEFECTVSGKPVPTVNWMKNGD-VVIP 373
Query: 499 EDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDP-----TWIVKQPE 553
D + + L I K G Y CVA N+ G A+ L + P + + P
Sbjct: 374 SDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPR 433
Query: 554 ----YAVVQRGSMVSFECKVKHDHTL-SLTVLWLK--DNRELPSDERFTVDKDHLVVADV 606
V R +S+ + + + TV + + DNRE + L V ++
Sbjct: 434 DVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNRERALNTT-QPGSLQLTVGNL 492
Query: 607 SDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLS 666
+ T+ VA +S + V P VP P +L+ S+ ++
Sbjct: 493 KPEAMYTFRVVAYNEWGPGESSQPIKVATQ-----PELQVPGPVENLQAVSTSPTSILIT 547
Query: 667 WTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNS 726
W P N P+ + + + EV G + L + YS R +A N
Sbjct: 548 WEPPAYANGPVQGYRLFCTEVSTGK---EQNIEVDGLSYKLE-GLKKFTEYSLRFLAYNR 603
Query: 727 IGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSW 786
G + ++ +T + P P V ++ ++W P NG YK+
Sbjct: 604 YGPGVSTD-DITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRH 662
Query: 787 RQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGE---D 843
R+ E ++ N+ Y+ +G Y +V A+ G P + E D
Sbjct: 663 RKTTRRGEMETLEPNNLW-YLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLD 721
Query: 844 LPMVA--PGNVRVNVVNSTLAEVHWDPV--PLKSIRGHLQGYRI---YYWKTQSSSKRNR 896
V P ++ V + + + W P P +RG++ GY + Y + SK+
Sbjct: 722 ESQVPDQPSSLHVRPQTNCII-MSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRY 780
Query: 897 RHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEG--------------PASPD 942
IE+ LE SHY ++++ N GEG P P
Sbjct: 781 YSIER----------------LESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPV 824
Query: 943 RVF----NTPEGVPSA------PSSLKIVNPTLDSLTLEWDPPSHPNGILTE----YTLK 988
+ + P VP P ++ V T D++ + W S P T YT++
Sbjct: 825 DYYPLLDDFPTSVPDLSTPMLPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVR 884
Query: 989 YQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTV 1048
++ S D +T L +T Y+F + S + TT
Sbjct: 885 WRTSFSASAKYKSED----TTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTY 940
Query: 1049 DEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISWE--YEGPEHVNFYVEYGVAGSK 1106
+ A P ++ +T +SW+ E + Y+ +
Sbjct: 941 EAAPTSAPK-----------DLTVITREGKPRAVIVSWQPPLEANGKITAYILFYTLDKN 989
Query: 1107 ---EEWRKEIVNGSRSFFGLKGLMPGTAYKVRVGAVGDSG 1143
++W E ++G R + L T Y R+ A G
Sbjct: 990 IPIDDWIMETISGDRLTHQIMDLNLDTMYYFRIQARNSKG 1029
Score = 43.1 bits (100), Expect = 0.002
Identities = 34/141 (24%), Positives = 57/141 (40%), Gaps = 13/141 (9%)
Query: 51 QSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMS 110
Q P + + ++ V++C G PPPSF+W R + + ++ G+ LI N+
Sbjct: 244 QRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQL-RSKKYSLLGGSNLLISNVTD 302
Query: 111 EGKAETYEGVYQC--TARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCR 168
+ G+Y C T +NE +A + V+ P W + + C
Sbjct: 303 DD-----SGMYTCVVTYKNENISASAELTVLVPP----WFLNHPSNLYAYESMDIEFECT 353
Query: 169 PPIGLPPPIIFWMDNSFQRLP 189
G P P + WM N +P
Sbjct: 354 VS-GKPVPTVNWMKNGDVVIP 373
Score = 35.4 bits (80), Expect = 0.36
Identities = 71/332 (21%), Positives = 124/332 (37%), Gaps = 45/332 (13%)
Query: 646 VPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQT 705
VP+ P L + Q + + +SWTP + N + +II Y + P + V Q
Sbjct: 725 VPDQPSSLHVRPQTN-CIIMSWTPPLNPNIVVRGYIIGY--GVGSP--YAETVRVDSKQR 779
Query: 706 TAQL-KLSPYVNYSFRVMAVNSIGKSLP--SEASEQYLTKASEP-------DKNPTAVEG 755
+ +L +Y + A N+ G+ +P A+ + +T ++P D PT+V
Sbjct: 780 YYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPD 839
Query: 756 LGSEP-------------DNLVITWKPLNGFESNGPGLQ---YKVSWRQK-DGDDEWTSV 798
L + D + ++W N N + Y V WR ++ S
Sbjct: 840 LSTPMLPPVGVQAVALTHDAVRVSWAD-NSVPKNQKTSEVRLYTVRWRTSFSASAKYKSE 898
Query: 799 VVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVN 858
++S Y +G Y V + + + E P AP ++ V
Sbjct: 899 DTTSLS-YTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITRE 957
Query: 859 ST--LAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKIL-TFQGSKTHGML 915
V W P PL++ G + Y ++Y ++ I+ I+ T G + +
Sbjct: 958 GKPRAVIVSWQP-PLEA-NGKITAYILFYTLDKNIP------IDDWIMETISGDRLTHQI 1009
Query: 916 PGLEPFSHYTLNVRVVNGKGEGPASPDRVFNT 947
L + Y ++ N KG GP S +F T
Sbjct: 1010 MDLNLDTMYYFRIQARNSKGVGPLSDPILFRT 1041
Score = 34.7 bits (78), Expect = 0.61
Identities = 36/127 (28%), Positives = 55/127 (43%), Gaps = 11/127 (8%)
Query: 624 SVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIE 683
S++A A APT P + + + ++V +SW P + N IT +I+
Sbjct: 932 SMTAHATTYEAAPTSAPKDLTVITR--------EGKPRAVIVSWQPPLEANGKITAYILF 983
Query: 684 YEDAMHKP-GLWHHQTEVSGTQTTAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLT 741
Y + P W +T +SG + T Q+ L+ Y FR+ A NS G S+
Sbjct: 984 YTLDKNIPIDDWIMET-ISGDRLTHQIMDLNLDTMYYFRIQARNSKGVGPLSDPILFRTL 1042
Query: 742 KASEPDK 748
K PDK
Sbjct: 1043 KVEHPDK 1049
>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2b [Homo sapiens]
Length = 1378
Score = 211 bits (536), Expect = 5e-54
Identities = 234/965 (24%), Positives = 381/965 (39%), Gaps = 127/965 (13%)
Query: 21 LFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSW 80
L LC L V +D L PP I + P D I+ E + C+A+G+P P+ W
Sbjct: 9 LLLCGF---LYVRVDGSRLRQEDFPPRIVEH-PSDVIVSKGEPTTLNCKAEGRPTPTIEW 64
Query: 81 TRNGTHFDIDKDPLVTMK---PGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNI 137
++G + DKD + + P + I+ +++ EG Y C ARN G AVS N
Sbjct: 65 YKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNA 124
Query: 138 VVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQG 197
+ + ++ + + +G+ +L C+PP G P P I+W + + + ER+S
Sbjct: 125 SLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIR 184
Query: 198 LNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEF 257
G L SN D Y C T + ++ D+ A L+ E
Sbjct: 185 -GGKLMISNTRKSDAGM-YTCVG----TNMVGER--------------DSDPAELTVFE- 223
Query: 258 YGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTV 317
PTFL N+ L + C +G P P + W K+D LP+ R
Sbjct: 224 ---------RPTFLR---RPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYD 271
Query: 318 YKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGED 377
K+ + TL+I D G Y CIA+N +G + + ++ V+A P ++ P++ +++ G
Sbjct: 272 IKD-DYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRT 330
Query: 378 GTLICRANGNPKPRISWLTNGVPIEIAPDDP-------SRKIDGDTIIFSNVQERSSAVY 430
T C GNP+P + W G + P+ P S GD I +N+Q + Y
Sbjct: 331 VTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTI-TNIQRSDAGYY 389
Query: 431 QCNASNEYGYLLANAFVNV----LAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTI 486
C A G +LA A + V PP I+ + + ALL C G PLP I
Sbjct: 390 ICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVI 449
Query: 487 EWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPT 546
W K + + E GTL+I + TGTYTCVA + G L++ +
Sbjct: 450 SWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESG 509
Query: 547 WIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADV 606
+ + Y + S + +V S+T+ W T+ ++
Sbjct: 510 ATISK-NYDLSDLPGPPS-KPQVTDVTKNSVTLSWQPGTPG-------TLPASAYIIEAF 560
Query: 607 SDDDSGTYTCVAN---TTLDSVSA---------------SAVLSVVAPTPTPAPVYDVPN 648
S S ++ VAN TTL +V LS +P P D+
Sbjct: 561 SQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISP 620
Query: 649 P-------PFDLELTDQLDK----------SVQLSWTPGDDNNSPITKFIIEYE--DAMH 689
P EL D L + +VQ++WT D I + + Y +
Sbjct: 621 PAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTV-DRQPQFIQGYRVMYRQTSGLQ 679
Query: 690 KPGLWHHQTEVSGTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTK--ASEP 746
W + T+ +A L L V Y +V + + + SE+ T+ S P
Sbjct: 680 ATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAP 739
Query: 747 DKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKY 806
++ T + ++ ++W P NG +YK+ + V A +
Sbjct: 740 PQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSV 799
Query: 807 IVSGTPTFVPYLIKVQALNDMGFA----PEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLA 862
I+ G + Y ++V A G P+P +++G E ++ N N + +
Sbjct: 800 IIGGLFPGIQYRVEVAASTSAGVGVKSEPQP-IIIGRRNE--VVITENN---NSITEQIT 853
Query: 863 EVHWDPVPLKSIRGH----LQGYRIY-YWKTQSSSKRNRRHIEKKILTFQ----GSKTHG 913
+V P + I G L G+ I+ YW+ ++ R+ + +TFQ G ++G
Sbjct: 854 DVVKQPAFIAGIGGACWVILMGFSIWLYWR-----RKKRKGLSNYAVTFQRGDGGLMSNG 908
Query: 914 MLPGL 918
PGL
Sbjct: 909 SRPGL 913
Score = 166 bits (420), Expect = 1e-40
Identities = 203/821 (24%), Positives = 336/821 (40%), Gaps = 108/821 (13%)
Query: 284 RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTL--------QIIHV--SEA 333
+G +L C AEG PTP I W K+ + ++ ++ L +I+H S+
Sbjct: 44 KGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKP 103
Query: 334 DSGNYQCIAKNALG-AIHHTISVRVKAA-PYWITAPQNLVLSPGEDGTLICRA-NGNPKP 390
D G+Y C+A+N LG A+ S+ V + P ++V++ GE L C+ G+P+P
Sbjct: 104 DEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEP 163
Query: 391 RISWLTNGVPIEIAPDDPSRKID--GDTIIFSNVQERSSAVYQCNASNEYGYLLAN-AFV 447
I W + V I DD +I G ++ SN ++ + +Y C +N G ++ A +
Sbjct: 164 TIYWKKDKVRI----DDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAEL 219
Query: 448 NVLAEPPRILTPANTLYQVIANRPAL-LDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE 506
V P + P N QV+ A+ C G P PT+ W K + L Y + +
Sbjct: 220 TVFERPTFLRRPIN---QVVLEEEAVEFRCQVQGDPQPTVRWKKD--DADLPRGRYDIKD 274
Query: 507 NGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFE 566
+ TL I GTY C+A N++G + L ++ P V +P +V +G V+F
Sbjct: 275 DYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFP 334
Query: 567 CKVKHDHTLSLTVLWLKD--------NRELPSDERFTVD-KDHLVVADVSDDDSGTYTCV 617
C+ K + V W K+ N+ + R +V L + ++ D+G Y C
Sbjct: 335 CETKGNP--QPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQ 392
Query: 618 ANTTLDSVSASA---VLSVVAPTPTPAPVYDVPNPPFDLELTDQL------DKSVQLSWT 668
A T S+ A A V V+ P P + N ++ T L D +SW
Sbjct: 393 ALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWL 452
Query: 669 ------PGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVM 722
PG D + I+ + + L + +GT T S ++S
Sbjct: 453 KEGFTFPGRD-----PRATIQEQGTLQIKNL---RISDTGTYTCVATSSSGETSWS---- 500
Query: 723 AVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQY 782
AV + +S + + L+ P P + +++ ++W+P G P Y
Sbjct: 501 AVLDVTESGATISKNYDLSDLPGPPSKPQVTD---VTKNSVTLSWQP--GTPGTLPASAY 555
Query: 783 KVSWRQKDGDDEWTSVV-VANVSKYIVSGTPTFVPYLIKVQALNDMGFA-PEPA------ 834
+ + + W +V + Y V G YL V+A+N G + P P
Sbjct: 556 IIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRT 615
Query: 835 --VVMGHSGEDLPMVAP--GNVRVN-----VVNSTLAEVHW--DPVPLKSIRGHLQGYRI 883
+ G D V G+V V V+ T +V W D P +QGYR+
Sbjct: 616 QDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQP-----QFIQGYRV 670
Query: 884 YYWKTQS-SSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPD 942
Y +T + + ++++ K+ T + +L L+ Y + VR + +G S
Sbjct: 671 MYRQTSGLQATSSWQNLDAKVPT----ERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSES 726
Query: 943 RVFNTPEGVPSAP----SSLKIVNPTLDSLTLEWD--PPSHPNGILTEYTLKYQPINSTH 996
+ T E PSAP + L + + S+++ WD PP H NGI+ EY + +
Sbjct: 727 KTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRF 786
Query: 997 ELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1037
+ VD I + + L +Y+ A TSAG G
Sbjct: 787 HINKTVDAAIRS----VIIGGLFPGIQYRVEVAASTSAGVG 823
Score = 120 bits (301), Expect = 8e-27
Identities = 212/908 (23%), Positives = 338/908 (37%), Gaps = 126/908 (13%)
Query: 361 PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDP-SRKI---DGDT 416
P + P ++++S GE TL C+A G P P I W +G +E DDP S ++ G
Sbjct: 31 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 90
Query: 417 IIFSNVQERSS----AVYQCNASNEYGYLLA-NAFVNV-LAEPPRILTPANTLYQVIANR 470
V R S Y C A N G ++ NA + V L P + + V A
Sbjct: 91 FFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVV--VAAGE 148
Query: 471 PALLDCAF-FGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARN 529
PA+L+C G P PTI W K K ++ + G L I +K G YTCV N
Sbjct: 149 PAILECQPPRGHPEPTIYWKKD-KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTN 207
Query: 530 KLGMAKNE-VHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNREL 588
+G ++ L + + +++P VV V F C+V+ D TV W KD+ +L
Sbjct: 208 MVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDP--QPTVRWKKDDADL 265
Query: 589 PSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPN 648
P D L + D GTY C+A + + ASA L+V AP
Sbjct: 266 PRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAP------------ 313
Query: 649 PPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMH-----KPGLWHHQTEVS-- 701
P F + DQ+ + P + +P + E + + +P + + VS
Sbjct: 314 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 373
Query: 702 GTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPD 761
G T ++ S Y + + V G L E P P ++G ++
Sbjct: 374 GDLTITNIQRSDAGYYICQALTV--AGSILAKAQLEVTDVLTDRPP--PIILQGPANQ-- 427
Query: 762 NLVITWKPLNGFESNGPGLQYKVSWRQKD----GDDEWTSVV---VANVSKYIVSGTPTF 814
L + L ++ G L +SW ++ G D ++ + +S T T+
Sbjct: 428 TLAVDGTALLKCKATGDPLPV-ISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTY 486
Query: 815 VPYLIKVQALNDMGFAPEPAVV-MGHSG---------EDLPMVAPGNVRVNVVNSTLAEV 864
A + G AV+ + SG DLP P +V V +
Sbjct: 487 T-----CVATSSSGETSWSAVLDVTESGATISKNYDLSDLPG-PPSKPQVTDVTKNSVTL 540
Query: 865 HWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHY 924
W P ++ + +S + H++ + T +G L P + Y
Sbjct: 541 SWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRG---------LRPNTIY 591
Query: 925 TLNVRVVNGKGEGPASP--DRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPS--HPNG 980
VR +N +G SP D V P+ + V L + + P P
Sbjct: 592 LFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTT 651
Query: 981 ILTEYTLKYQP---------------INSTHELGPLVDLKIPANKTRWTLKNLNFSTRYK 1025
+ +T+ QP + +T L D K+P ++ L NL Y+
Sbjct: 652 VQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNL-DAKVPTERSA-VLVNLKKGVTYE 709
Query: 1026 FYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAE-TYANI 1084
+ G + V T +EA PP ++ LT + T ++
Sbjct: 710 IKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQ-----------SVTVLTVGSYNSTSISV 758
Query: 1085 SWEYEGPEHVNFYV-EYGVAGSKEEWRKEI---VNGSRSFFGLKGLMPGTAYKVRVGAVG 1140
SW+ P+H N + EY + E R I V+ + + GL PG Y+V V A
Sbjct: 759 SWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAAST 818
Query: 1141 DSGF-VSSED------------VFETGPAMASRQVDIATQGWFI-GLMCAVALLILILLI 1186
+G V SE + E ++ + D+ Q FI G+ A ++++ I
Sbjct: 819 SAGVGVKSEPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSI 878
Query: 1187 VCFIRRNK 1194
+ RR K
Sbjct: 879 WLYWRRKK 886
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 209 bits (533), Expect = 1e-53
Identities = 227/941 (24%), Positives = 373/941 (39%), Gaps = 124/941 (13%)
Query: 45 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMK---PGT 101
PP I + P D I+ E + C+A+G+P P+ W ++G + DKD + + P
Sbjct: 46 PPRIVEH-PSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSG 104
Query: 102 GTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ 161
+ I+ +++ EG Y C ARN G AVS N + + ++ + + +G+
Sbjct: 105 SLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGE 164
Query: 162 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYAR 221
+L C+PP G P P I+W + + + ER+S G L SN D Y C
Sbjct: 165 PAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIR-GGKLMISNTRKSDAGM-YTCVG- 221
Query: 222 FNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKE 281
T + ++ D+ A L+ E PTFL N+
Sbjct: 222 ---TNMVGER--------------DSDPAELTVFE----------RPTFLR---RPINQV 251
Query: 282 ELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCI 341
L + C +G P P + W K+D LP+ R K+ + TL+I D G Y CI
Sbjct: 252 VLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKD-DYTLRIKKTMSTDEGTYMCI 310
Query: 342 AKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPI 401
A+N +G + + ++ V+A P ++ P++ +++ G T C GNP+P + W G
Sbjct: 311 AENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQN 370
Query: 402 EIAPDDP-------SRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNV----L 450
+ P+ P S GD I +N+Q + Y C A G +LA A + V
Sbjct: 371 LLFPNQPQQPNSRCSVSPTGDLTI-TNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLT 429
Query: 451 AEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTL 510
PP I+ + + ALL C G PLP I W K + + E GTL
Sbjct: 430 DRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTL 489
Query: 511 EIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVK 570
+I + TGTYTCVA + G L++ + + + Y + S + +V
Sbjct: 490 QIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISK-NYDLSDLPGPPS-KPQVT 547
Query: 571 HDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVAN---TTLDSVSA 627
S+T+ W T+ ++ S S ++ VAN TTL +V
Sbjct: 548 DVTKNSVTLSWQPGTPG-------TLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRG 600
Query: 628 ---------------SAVLSVVAPTPTPAPVYDVPNP-------PFDLELTDQLDK---- 661
LS +P P D+ P EL D L +
Sbjct: 601 LRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNP 660
Query: 662 ------SVQLSWTPGDDNNSPITKFIIEYE--DAMHKPGLWHHQTEVSGTQTTAQL-KLS 712
+VQ++WT D I + + Y + W + T+ +A L L
Sbjct: 661 VVLTPTTVQVTWTV-DRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLK 719
Query: 713 PYVNYSFRVMAVNSIGKSLPSEASEQYLTK--ASEPDKNPTAVEGLGSEPDNLVITWKPL 770
V Y +V + + + SE+ T+ S P ++ T + ++ ++W P
Sbjct: 720 KGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPP 779
Query: 771 NGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFA 830
NG +YK+ + V A + I+ G + Y ++V A G
Sbjct: 780 PPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVG 839
Query: 831 ----PEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGH----LQGYR 882
P+P +++G E ++ N N + + +V P + I G L G+
Sbjct: 840 VKSEPQP-IIIGRRNE--VVITENN---NSITEQITDVVKQPAFIAGIGGACWVILMGFS 893
Query: 883 IY-YWKTQSSSKRNRRHIEKKILTFQ----GSKTHGMLPGL 918
I+ YW+ ++ R+ + +TFQ G ++G PGL
Sbjct: 894 IWLYWR-----RKKRKGLSNYAVTFQRGDGGLMSNGSRPGL 929
Score = 166 bits (420), Expect = 1e-40
Identities = 203/821 (24%), Positives = 336/821 (40%), Gaps = 108/821 (13%)
Query: 284 RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTL--------QIIHV--SEA 333
+G +L C AEG PTP I W K+ + ++ ++ L +I+H S+
Sbjct: 60 KGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKP 119
Query: 334 DSGNYQCIAKNALG-AIHHTISVRVKAA-PYWITAPQNLVLSPGEDGTLICRA-NGNPKP 390
D G+Y C+A+N LG A+ S+ V + P ++V++ GE L C+ G+P+P
Sbjct: 120 DEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEP 179
Query: 391 RISWLTNGVPIEIAPDDPSRKID--GDTIIFSNVQERSSAVYQCNASNEYGYLLAN-AFV 447
I W + V I DD +I G ++ SN ++ + +Y C +N G ++ A +
Sbjct: 180 TIYWKKDKVRI----DDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAEL 235
Query: 448 NVLAEPPRILTPANTLYQVIANRPAL-LDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE 506
V P + P N QV+ A+ C G P PT+ W K + L Y + +
Sbjct: 236 TVFERPTFLRRPIN---QVVLEEEAVEFRCQVQGDPQPTVRWKKD--DADLPRGRYDIKD 290
Query: 507 NGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFE 566
+ TL I GTY C+A N++G + L ++ P V +P +V +G V+F
Sbjct: 291 DYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFP 350
Query: 567 CKVKHDHTLSLTVLWLKD--------NRELPSDERFTVD-KDHLVVADVSDDDSGTYTCV 617
C+ K + V W K+ N+ + R +V L + ++ D+G Y C
Sbjct: 351 CETKGNP--QPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQ 408
Query: 618 ANTTLDSVSASA---VLSVVAPTPTPAPVYDVPNPPFDLELTDQL------DKSVQLSWT 668
A T S+ A A V V+ P P + N ++ T L D +SW
Sbjct: 409 ALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWL 468
Query: 669 ------PGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVM 722
PG D + I+ + + L + +GT T S ++S
Sbjct: 469 KEGFTFPGRD-----PRATIQEQGTLQIKNL---RISDTGTYTCVATSSSGETSWS---- 516
Query: 723 AVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQY 782
AV + +S + + L+ P P + +++ ++W+P G P Y
Sbjct: 517 AVLDVTESGATISKNYDLSDLPGPPSKPQVTD---VTKNSVTLSWQP--GTPGTLPASAY 571
Query: 783 KVSWRQKDGDDEWTSVV-VANVSKYIVSGTPTFVPYLIKVQALNDMGFA-PEPA------ 834
+ + + W +V + Y V G YL V+A+N G + P P
Sbjct: 572 IIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRT 631
Query: 835 --VVMGHSGEDLPMVAP--GNVRVN-----VVNSTLAEVHW--DPVPLKSIRGHLQGYRI 883
+ G D V G+V V V+ T +V W D P +QGYR+
Sbjct: 632 QDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQP-----QFIQGYRV 686
Query: 884 YYWKTQS-SSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPD 942
Y +T + + ++++ K+ T + +L L+ Y + VR + +G S
Sbjct: 687 MYRQTSGLQATSSWQNLDAKVPT----ERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSES 742
Query: 943 RVFNTPEGVPSAP----SSLKIVNPTLDSLTLEWD--PPSHPNGILTEYTLKYQPINSTH 996
+ T E PSAP + L + + S+++ WD PP H NGI+ EY + +
Sbjct: 743 KTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRF 802
Query: 997 ELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1037
+ VD I + + L +Y+ A TSAG G
Sbjct: 803 HINKTVDAAIRS----VIIGGLFPGIQYRVEVAASTSAGVG 839
Score = 120 bits (301), Expect = 8e-27
Identities = 212/908 (23%), Positives = 338/908 (37%), Gaps = 126/908 (13%)
Query: 361 PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDP-SRKI---DGDT 416
P + P ++++S GE TL C+A G P P I W +G +E DDP S ++ G
Sbjct: 47 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 106
Query: 417 IIFSNVQERSS----AVYQCNASNEYGYLLA-NAFVNV-LAEPPRILTPANTLYQVIANR 470
V R S Y C A N G ++ NA + V L P + + V A
Sbjct: 107 FFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVV--VAAGE 164
Query: 471 PALLDCAF-FGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARN 529
PA+L+C G P PTI W K K ++ + G L I +K G YTCV N
Sbjct: 165 PAILECQPPRGHPEPTIYWKKD-KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTN 223
Query: 530 KLGMAKNE-VHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNREL 588
+G ++ L + + +++P VV V F C+V+ D TV W KD+ +L
Sbjct: 224 MVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDP--QPTVRWKKDDADL 281
Query: 589 PSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPN 648
P D L + D GTY C+A + + ASA L+V AP
Sbjct: 282 PRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAP------------ 329
Query: 649 PPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMH-----KPGLWHHQTEVS-- 701
P F + DQ+ + P + +P + E + + +P + + VS
Sbjct: 330 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 389
Query: 702 GTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPD 761
G T ++ S Y + + V G L E P P ++G ++
Sbjct: 390 GDLTITNIQRSDAGYYICQALTV--AGSILAKAQLEVTDVLTDRPP--PIILQGPANQ-- 443
Query: 762 NLVITWKPLNGFESNGPGLQYKVSWRQKD----GDDEWTSVV---VANVSKYIVSGTPTF 814
L + L ++ G L +SW ++ G D ++ + +S T T+
Sbjct: 444 TLAVDGTALLKCKATGDPLPV-ISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTY 502
Query: 815 VPYLIKVQALNDMGFAPEPAVV-MGHSG---------EDLPMVAPGNVRVNVVNSTLAEV 864
A + G AV+ + SG DLP P +V V +
Sbjct: 503 T-----CVATSSSGETSWSAVLDVTESGATISKNYDLSDLPG-PPSKPQVTDVTKNSVTL 556
Query: 865 HWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHY 924
W P ++ + +S + H++ + T +G L P + Y
Sbjct: 557 SWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRG---------LRPNTIY 607
Query: 925 TLNVRVVNGKGEGPASP--DRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPS--HPNG 980
VR +N +G SP D V P+ + V L + + P P
Sbjct: 608 LFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTT 667
Query: 981 ILTEYTLKYQP---------------INSTHELGPLVDLKIPANKTRWTLKNLNFSTRYK 1025
+ +T+ QP + +T L D K+P ++ L NL Y+
Sbjct: 668 VQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNL-DAKVPTERSA-VLVNLKKGVTYE 725
Query: 1026 FYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAE-TYANI 1084
+ G + V T +EA PP ++ LT + T ++
Sbjct: 726 IKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQ-----------SVTVLTVGSYNSTSISV 774
Query: 1085 SWEYEGPEHVNFYV-EYGVAGSKEEWRKEI---VNGSRSFFGLKGLMPGTAYKVRVGAVG 1140
SW+ P+H N + EY + E R I V+ + + GL PG Y+V V A
Sbjct: 775 SWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAAST 834
Query: 1141 DSGF-VSSED------------VFETGPAMASRQVDIATQGWFI-GLMCAVALLILILLI 1186
+G V SE + E ++ + D+ Q FI G+ A ++++ I
Sbjct: 835 SAGVGVKSEPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSI 894
Query: 1187 VCFIRRNK 1194
+ RR K
Sbjct: 895 WLYWRRKK 902
Score = 40.0 bits (92), Expect = 0.015
Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 10/113 (8%)
Query: 22 FLCQMISALEVPLDPKLLE--DLV--QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPS 77
++CQ ++ L LE D++ +PP I Q P + + +++C+A G P P
Sbjct: 405 YICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPV 464
Query: 78 FSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERG 130
SW + G F +DP T++ GTL I + G Y C A + G
Sbjct: 465 ISWLKEGFTFP-GRDPRATIQE-QGTLQIKNLRISDT----GTYTCVATSSSG 511
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 198 bits (504), Expect = 2e-50
Identities = 214/830 (25%), Positives = 347/830 (41%), Gaps = 105/830 (12%)
Query: 361 PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFS 420
P +I P++ G + +C+A G PKPRI+W+ G + + DG +
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL- 91
Query: 421 NVQ----ERSSAVYQCNASNEYGYLLANAFVNVLAE---PPRI--LTPANTLYQVIANRP 471
+Q +R A+Y+C A+N G + +A ++VL E PP + L V R
Sbjct: 92 RIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKART 151
Query: 472 ALLDCAFFGSPLPTIEWFKG--AKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARN 529
A + CA G+P P I WFK A +G L+I +++ G Y CVA N
Sbjct: 152 ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATN 211
Query: 530 KLGM-----AKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKD 584
G A V + P + + P V G V+ C V W+
Sbjct: 212 SAGTRYSAPANLYVRVRRVAPRFSI-PPSSQEVMPGGSVNLTCVAV--GAPMPYVKWMMG 268
Query: 585 NRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVY 644
EL ++ V ++ L +++V S YTCVA ++L + A+A ++V A
Sbjct: 269 AEELTKEDEMPVGRNVLELSNVV--RSANYTCVAISSLGMIEATAQVTVKA--------- 317
Query: 645 DVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQ 704
+P PP DL +T+ SV L+W G N+ P+T + I+Y A G EV G
Sbjct: 318 -LPKPPIDLVVTETTATSVTLTWDSG--NSEPVTYYGIQYRAA----GTEGPFQEVDGVA 370
Query: 705 TTAQL--KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDN 762
TT LSP+ Y+FRV+AVNSIG+ PSEA + T P P V+
Sbjct: 371 TTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEA-VRARTGEQAPSSPPRRVQARMLSAST 429
Query: 763 LVITWKPLNGFESNGPGLQYKVSWR--QKDGDDEWTSVVVANVSKYIVSGTPTFVP---Y 817
+++ W+P E NG Y+V + + + W N +++ + +P Y
Sbjct: 430 MLVQWEPPE--EPNGLVRGYRVYYTPDSRRPPNAWHK---HNTDAGLLTTVGSLLPGITY 484
Query: 818 LIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGH 877
++V A +G P + + + +P P + + V + T ++ W P + I
Sbjct: 485 SLRVLAFTAVGDGPPSPTIQVKTQQGVP-AQPADFQAEVESDTRIQLSWLLPPQERI--- 540
Query: 878 LQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEG 937
Y + YW + ++++ +TF + ++ L L+P + Y + + G G
Sbjct: 541 -IMYELVYWAAEDEDQQHK-------VTFDPTSSY-TLEDLKPDTLYRFQLAARSDMGVG 591
Query: 938 PASPDRVFNTPEGVPSAPSSLKIVNPTLDSLT--LEWDPP--SHPNGILTEYTLKYQPIN 993
+P T + PSAP K++ ++ S T + W PP NG++T+Y++ Y+ ++
Sbjct: 592 VFTPTIEARTAQSTPSAPPQ-KVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVD 650
Query: 994 STHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGI 1053
+VD I + W L L T Y+ + A T G G + + V T DE
Sbjct: 651 GEDRGRHVVD-GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRT-DE--- 705
Query: 1054 LPPDVGAGKVQAVNPRISNLTAAAAETYANISWEYEGPEHVN-----FYVEY-------- 1100
DV +G + V N TA ++ W+ P + + V Y
Sbjct: 706 ---DVPSGPPRKVEVEPLNSTA------VHVYWKLPVPSKQHGQIRGYQVTYVRLENGEP 756
Query: 1101 -------GVAGSKEEWRKEIVNGSRSFFGLKGLMPGTAYKVRVGAVGDSG 1143
V ++ +WR E + + GL P T Y V V A G
Sbjct: 757 RGLPIIQDVMLAEAQWRPEESEDYET--TISGLTPETTYSVTVAAYTTKG 804
Score = 179 bits (453), Expect = 2e-44
Identities = 207/903 (22%), Positives = 350/903 (38%), Gaps = 90/903 (9%)
Query: 283 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEK------TLQIIHVSEADSG 336
L G V S C A G P P I W K+ + R F+ +Q + V + D
Sbjct: 45 LSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRV-QRDEA 103
Query: 337 NYQCIAKNALGAIHHTISVRV-------KAAPYWITAPQNLVLSPGEDGTLICRANGNPK 389
Y+C A N+LG I+ + + V P PQ V+ T++C A GNP
Sbjct: 104 IYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPD 163
Query: 390 PRISWLTNGVPIEIAPDDPS-RKIDGDTIIFSNVQERSSAVYQCNASNEYGYLL---ANA 445
P ISW + +P++ A + +++ + + +E Y+C A+N G AN
Sbjct: 164 PEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANL 223
Query: 446 FVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLH 505
+V V PR P ++ +V+ L C G+P+P ++W GA+ +++ V
Sbjct: 224 YVRVRRVAPRFSIPPSS-QEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPV-- 280
Query: 506 ENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSF 565
G + ++ + YTCVA + LGM + + +K + K P VV + S
Sbjct: 281 --GRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKA---LPKPPIDLVVTETTATSV 335
Query: 566 ECKVKHDHTLSLT---VLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTL 622
++ +T + + E P E V + +S + +A ++
Sbjct: 336 TLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSI 395
Query: 623 DSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFII 682
S +V A T AP +PP ++ ++ + W P ++ N + + +
Sbjct: 396 GRGPPSE--AVRARTGEQAP----SSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRV 449
Query: 683 EY-EDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLT 741
Y D+ P WH +G TT L P + YS RV+A ++G PS + Q T
Sbjct: 450 YYTPDSRRPPNAWHKHNTDAGLLTTVG-SLLPGITYSLRVLAFTAVGDGPPS-PTIQVKT 507
Query: 742 KASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVA 801
+ P P + + ++W + Y++ + + +D+ V
Sbjct: 508 QQGVP-AQPADFQAEVESDTRIQLSWL----LPPQERIIMYELVYWAAEDEDQQHKVTFD 562
Query: 802 NVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTL 861
S Y + Y ++ A +DMG + + + P P V + ST
Sbjct: 563 PTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTT 622
Query: 862 AEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGM--LPGLE 919
V W P P S G + Y + Y + RH+ I S+ H L GLE
Sbjct: 623 VRVSWVPPPADSRNGVITQYSVAYEAVDGEDR--GRHVVDGI-----SREHSSWDLVGLE 675
Query: 920 PFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPS---SLKIVNPTLDSLTLEWDPPS 976
++ Y + VR G GP S + T E VPS P ++ +N T + + PS
Sbjct: 676 KWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPS 735
Query: 977 HPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRW----------TLKNLNFSTRYKF 1026
+G + Y + Y + + G + + + +W T+ L T Y
Sbjct: 736 KQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSV 795
Query: 1027 YFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISW 1086
A T+ G G++ + VTT AV R + + + A A + W
Sbjct: 796 TVAAYTTKGDGARSKPKIVTTTG---------------AVPGRPTMMISTTAMNTALLQW 840
Query: 1087 ----EYEGPEHVNFYVEYGVAGSKEEWRKEIVNGSR--SFFGLKGLMPGTAYKVRVGAVG 1140
E G E + + ++Y A +E R ++ + F + GL GT Y R+ A
Sbjct: 841 HPPKELPG-ELLGYRLQYCRA---DEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKN 896
Query: 1141 DSG 1143
+G
Sbjct: 897 RAG 899
Score = 133 bits (335), Expect = 1e-30
Identities = 140/559 (25%), Positives = 230/559 (41%), Gaps = 56/559 (10%)
Query: 610 DSGTYTCVANTTLDSVSASAVLSVVA-----PTPT--PAPVYDVPNPPFDLELTDQLDKS 662
D+G T V + + VL+ A P+PT VP P D + + D
Sbjct: 468 DAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTR 527
Query: 663 VQLSWTPGDDNNSPITKFII---EYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSF 719
+QLSW + + + E ED HK + + + T LK P Y F
Sbjct: 528 IQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTF-----DPTSSYTLEDLK--PDTLYRF 580
Query: 720 RVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPG 779
++ A + +G + + E T S P P V + + ++W P NG
Sbjct: 581 QLAARSDMGVGVFTPTIEAR-TAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVI 639
Query: 780 LQYKVSWRQKDGDDEWTSVVVA---NVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVV 836
QY V++ DG+D VV S + + G + Y + V+A D+G PE + V
Sbjct: 640 TQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPV 699
Query: 837 MGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD-PVPLKSIRGHLQGYRIYYWKTQSSSKRN 895
+ + ED+P P V V +NST V+W PVP K G ++GY++ Y + ++ R
Sbjct: 700 LVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQ-HGQIRGYQVTYVRLENGEPRG 758
Query: 896 RRHIEKKILT------FQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPE 949
I+ +L + + GL P + Y++ V KG+G S ++ T
Sbjct: 759 LPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTG 818
Query: 950 GVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPAN 1009
VP P ++ I +++ L+W PP G L Y L+Y + + +
Sbjct: 819 AVPGRP-TMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARP----NTIDFGKD 873
Query: 1010 KTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPR 1069
+T+ L+ T Y F A+ AG G + +E T P D+ +G Q N
Sbjct: 874 DQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRT--------PEDLPSGFPQ--NLH 923
Query: 1070 ISNLTAAAAETYANISWE-----YEGPEHVNFYVEYGVAGSKEEWRKEIVNGSRSFFGLK 1124
++ LT + E ++W+ +++ V + S++E + I +R F L
Sbjct: 924 VTGLTTSTTE----LAWDPPVLAERNGRIISYTVVFRDINSQQE-LQNITTDTR--FTLT 976
Query: 1125 GLMPGTAYKVRVGAVGDSG 1143
GL P T Y ++V A G
Sbjct: 977 GLKPDTTYDIKVRAWTSKG 995
Score = 133 bits (334), Expect = 1e-30
Identities = 237/1084 (21%), Positives = 401/1084 (36%), Gaps = 168/1084 (15%)
Query: 68 CEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARN 127
C+A G+P P +W + G + ++ G G+++ + + + E +Y+CTA N
Sbjct: 54 CQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR--IQPLRVQRDEAIYECTATN 111
Query: 128 ERG---AAVSNNIVVRPSRSPLWTKEKLEPI--TLQSGQSLVLPCRPPIGLPPPIIFWMD 182
G + +++ P + + P ++ ++ + C G P P I W
Sbjct: 112 SLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAG-GNPDPEISWFK 170
Query: 183 NSFQRLPQSE--RVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVIS 240
+ P + R+ Q +G L + E + Y C A + + V+V
Sbjct: 171 DFLPVDPATSNGRIKQLRSGALQIESS-EESDQGKYECVATNSAGTRYSAPANLYVRV-- 227
Query: 241 VDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP 300
R P F P S++E + G ++L C+A G P P
Sbjct: 228 -----------------------RRVAPRFSIPP---SSQEVMPGGSVNLTCVAVGAPMP 261
Query: 301 IIYW-------AKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTI 353
+ W KED M P R V L++ +V S NY C+A ++LG I T
Sbjct: 262 YVKWMMGAEELTKEDEM-PVGRNV-------LELSNV--VRSANYTCVAISSLGMIEATA 311
Query: 354 SVRVKAAPYWITAPQNLVLS-PGEDGTLICRANGNPKPRISWLTNGVPIEIA-PDDPSRK 411
V VKA P P +LV++ + +GN +P + G+ A + P ++
Sbjct: 312 QVTVKALP---KPPIDLVVTETTATSVTLTWDSGNSEPVTYY---GIQYRAAGTEGPFQE 365
Query: 412 IDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRP 471
+DG V ++ + +EY + + A ++ PP A T Q ++ P
Sbjct: 366 VDG-------VATTRYSIGGLSPFSEYAFRVL-AVNSIGRGPPSEAVRARTGEQAPSSPP 417
Query: 472 ALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVA---QKDSTGTYTCVAR 528
+ + ++W + + L V + + P A G T V
Sbjct: 418 RRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGS 477
Query: 529 NKLG-------MAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW 581
G +A V PT VK + Q F+ +V+ D + L+ W
Sbjct: 478 LLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQ---PADFQAEVESDTRIQLS--W 532
Query: 582 LKDNRELPSDERFTVDKDHLVVADVSDDDSG---TYTCVANTTLDSVSASAV-------- 630
L LP ER + + LV D+D T+ ++ TL+ + +
Sbjct: 533 L-----LPPQERIIMYE--LVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAAR 585
Query: 631 ----LSVVAPTPTPAPVYDVPN-PPFDLELTDQLDKSVQLSWT--PGDDNNSPITKFIIE 683
+ V PT P+ PP + +V++SW P D N IT++ +
Sbjct: 586 SDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVA 645
Query: 684 YEDAMHKPGLWHHQTEVSGTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTK 742
YE + H +S ++ L L + Y V A +G P S L +
Sbjct: 646 YEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVG---PGPESSPVLVR 702
Query: 743 ASE--PDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVV 800
E P P VE + + WK + +G Y+V++ + + + ++
Sbjct: 703 TDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPII 762
Query: 801 ANVS--------------KYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPM 846
+V + +SG Y + V A G + + +P
Sbjct: 763 QDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPG 822
Query: 847 VAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTF 906
+ +N+ L + H P K + G L GYR+ Y + + + F
Sbjct: 823 RPTMMISTTAMNTALLQWH----PPKELPGELLGYRLQYCRADEA--------RPNTIDF 870
Query: 907 QGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSA-PSSLKIVNPTL 965
H + GL + Y + N G G ++ TPE +PS P +L + T
Sbjct: 871 GKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEF-EKEIRTPEDLPSGFPQNLHVTGLTT 929
Query: 966 DSLTLEWDPP--SHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTR 1023
+ L WDPP + NG + YT+ ++ INS EL + TR+TL L T
Sbjct: 930 STTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNI------TTDTRFTLTGLKPDTT 983
Query: 1024 YKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYAN 1083
Y A TS GSG ++ ++ +P + +V A N R+ AAA +T
Sbjct: 984 YDIKVRAWTSKGSG------PLSPSIQSRTMPVE----QVFAKNFRV----AAAMKTSVL 1029
Query: 1084 ISWE 1087
+SWE
Sbjct: 1030 LSWE 1033
Score = 65.9 bits (159), Expect = 2e-10
Identities = 94/429 (21%), Positives = 158/429 (36%), Gaps = 53/429 (12%)
Query: 634 VAPTPTPAPVY-----DVPN-PPFDLELTDQLDKSVQLSWT-------PGDDNNSPITKF 680
V P P +PV DVP+ PP +E+ +V + W G +T
Sbjct: 690 VGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYV 749
Query: 681 IIE---------YEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSL 731
+E +D M W + E S T L+P YS V A + G
Sbjct: 750 RLENGEPRGLPIIQDVMLAEAQW--RPEESEDYETTISGLTPETTYSVTVAAYTTKGDGA 807
Query: 732 PSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDG 791
S+ + +T PT + + + ++ W P E G L Y++ + + D
Sbjct: 808 RSKP--KIVTTTGAVPGRPTMMIST-TAMNTALLQWHPPK--ELPGELLGYRLQYCRADE 862
Query: 792 DDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGN 851
T + + V+G Y+ ++ A N G E + + EDLP P N
Sbjct: 863 ARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEI-RTPEDLPSGFPQN 921
Query: 852 VRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKT 911
+ V + ++ E+ WDP L G + Y + + S E + +T + T
Sbjct: 922 LHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQ-------ELQNIT---TDT 971
Query: 912 HGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLE 971
L GL+P + Y + VR KG GP SP T + ++ S+ L
Sbjct: 972 RFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLS 1031
Query: 972 WD-PPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYA 1030
W+ P S+ + + + Q + ++ + R + +L +T Y F
Sbjct: 1032 WEVPDSYKSAVPFKILYNGQSV------------EVDGHSMRKLIADLQPNTEYSFVLMN 1079
Query: 1031 QTSAGSGSQ 1039
+ S+ G Q
Sbjct: 1080 RGSSAGGLQ 1088
Score = 45.4 bits (106), Expect = 3e-04
Identities = 61/268 (22%), Positives = 104/268 (38%), Gaps = 18/268 (6%)
Query: 21 LFLCQMISAL-EVPLDPKL--LEDLVQPPTITQ--QSPKDYIIDPRENIVIQCEAKGKPP 75
++ C ++L E+ KL LE+ PP P+ +++ + C A G P
Sbjct: 104 IYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPD 163
Query: 76 PSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVS- 134
P SW ++ D + +G L I E E+ +G Y+C A N G S
Sbjct: 164 PEISWFKDFLPVDPATSNGRIKQLRSGALQI----ESSEESDQGKYECVATNSAGTRYSA 219
Query: 135 -NNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSER 193
N+ VR R + G S+ L C +G P P + WM + + L + +
Sbjct: 220 PANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTC-VAVGAPMPYVKWMMGA-EELTKEDE 277
Query: 194 VSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLS 253
+ G N L SNV+ +Y C A + I+ ++VK + ++ + +
Sbjct: 278 MPVGRN-VLELSNVV---RSANYTCVA-ISSLGMIEATAQVTVKALPKPPIDLVVTETTA 332
Query: 254 DTEFYGAKSSRERPPTFLTPEGNASNKE 281
+ S P T+ + A+ E
Sbjct: 333 TSVTLTWDSGNSEPVTYYGIQYRAAGTE 360
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,652,506
Number of Sequences: 37866
Number of extensions: 2914923
Number of successful extensions: 16688
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 298
Number of HSP's successfully gapped in prelim test: 219
Number of HSP's that attempted gapping in prelim test: 6208
Number of HSP's gapped (non-prelim): 4837
length of query: 1304
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1190
effective length of database: 13,930,794
effective search space: 16577644860
effective search space used: 16577644860
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.