Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 77404397

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|77404397 staphylococcal nuclease domain containing 1 [Homo
sapiens]
         (910 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|77404397 staphylococcal nuclease domain containing 1 [Homo sa...  1812   0.0  
gi|38505161 tudor domain containing 1 [Homo sapiens]                   58   5e-08
gi|94421471 ring finger protein 17 [Homo sapiens]                      56   1e-07
gi|58197558 tudor domain containing 6 [Homo sapiens]                   54   9e-07
gi|145312259 tudor and KH domain containing isoform a [Homo sapi...    49   2e-05
gi|145312246 tudor and KH domain containing isoform b [Homo sapi...    49   2e-05
gi|145312270 tudor and KH domain containing isoform a [Homo sapi...    49   2e-05
gi|145312256 tudor and KH domain containing isoform a [Homo sapi...    49   2e-05
gi|169163653 PREDICTED: similar to tudor domain containing 1 [Ho...    48   4e-05
gi|169164192 PREDICTED: similar to tudor domain containing 1 [Ho...    48   4e-05
gi|169163210 PREDICTED: similar to tudor domain containing 1 [Ho...    48   4e-05
gi|112293287 tudor domain containing 7 [Homo sapiens]                  46   2e-04
gi|40255178 tudor domain containing 5 [Homo sapiens]                   44   5e-04
gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]          41   0.006
gi|170784859 serine/threonine kinase 31 isoform b [Homo sapiens]       39   0.029
gi|14602443 serine/threonine kinase 31 isoform a [Homo sapiens]        39   0.029
gi|170784856 serine/threonine kinase 31 isoform b [Homo sapiens]       39   0.029
gi|166851804 tudor domain containing 9 [Homo sapiens]                  36   0.14 
gi|28416940 Shwachman-Bodian-Diamond syndrome protein [Homo sapi...    35   0.32 
gi|189571674 cadherin-like 23 isoform 1 precursor [Homo sapiens]       33   1.2  
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]       32   2.7  
gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]             32   3.5  
gi|9910266 kinesin family member 15 [Homo sapiens]                     31   6.0  
gi|148806891 hypothetical protein LOC54906 [Homo sapiens]              31   6.0  
gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens]          30   7.8  
gi|90669307 cyclin B3 isoform 3 [Homo sapiens]                         30   7.8  
gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap...    30   7.8  
gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap...    30   7.8  

>gi|77404397 staphylococcal nuclease domain containing 1 [Homo
           sapiens]
          Length = 910

 Score = 1812 bits (4694), Expect = 0.0
 Identities = 910/910 (100%), Positives = 910/910 (100%)

Query: 1   MASSAQSGGSSGGPAVPTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLA 60
           MASSAQSGGSSGGPAVPTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLA
Sbjct: 1   MASSAQSGGSSGGPAVPTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLA 60

Query: 61  RRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNG 120
           RRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNG
Sbjct: 61  RRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNG 120

Query: 121 ENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTI 180
           ENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTI
Sbjct: 121 ENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTI 180

Query: 181 ENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGSET 240
           ENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGSET
Sbjct: 181 ENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGSET 240

Query: 241 PEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWS 300
           PEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWS
Sbjct: 241 PEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWS 300

Query: 301 IAVYTRGAEKLRAAERFAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKL 360
           IAVYTRGAEKLRAAERFAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKL
Sbjct: 301 IAVYTRGAEKLRAAERFAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKL 360

Query: 361 NSGDYKTIHLSSIRPPRLEGENTQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVD 420
           NSGDYKTIHLSSIRPPRLEGENTQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVD
Sbjct: 361 NSGDYKTIHLSSIRPPRLEGENTQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVD 420

Query: 421 YIRPASPATETVPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELL 480
           YIRPASPATETVPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELL
Sbjct: 421 YIRPASPATETVPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELL 480

Query: 481 AAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRL 540
           AAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRL
Sbjct: 481 AAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRL 540

Query: 541 KLYLPKETCLITFLLAGIECPRGARNLPGLVQEGEPFSEEATLFTKELVLQREVEVEVES 600
           KLYLPKETCLITFLLAGIECPRGARNLPGLVQEGEPFSEEATLFTKELVLQREVEVEVES
Sbjct: 541 KLYLPKETCLITFLLAGIECPRGARNLPGLVQEGEPFSEEATLFTKELVLQREVEVEVES 600

Query: 601 MDKAGNFIGWLHIDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAH 660
           MDKAGNFIGWLHIDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAH
Sbjct: 601 MDKAGNFIGWLHIDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAH 660

Query: 661 YEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIAS 720
           YEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIAS
Sbjct: 661 YEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIAS 720

Query: 721 HPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTL 780
           HPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTL
Sbjct: 721 HPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTL 780

Query: 781 SPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHV 840
           SPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHV
Sbjct: 781 SPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHV 840

Query: 841 TLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRA 900
           TLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRA
Sbjct: 841 TLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRA 900

Query: 901 DDADEFGYSR 910
           DDADEFGYSR
Sbjct: 901 DDADEFGYSR 910


>gi|38505161 tudor domain containing 1 [Homo sapiens]
          Length = 1189

 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 37/95 (38%), Positives = 51/95 (53%), Gaps = 6/95 (6%)

Query: 687 VTEITDDLHFYVQ--DVETGTQLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKF-VDG 743
           VTE      FYVQ    E    + +L  +++   A+    E  Y P +GE CIAK+ VD 
Sbjct: 270 VTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVH--EKDYIPVKGEVCIAKYTVDQ 327

Query: 744 EWYRARVEKVE-SPAKIHVFYIDYGNREVLPSTRL 777
            W RA ++ V+    K HV YIDYGN E++P  R+
Sbjct: 328 TWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRI 362



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 4/117 (3%)

Query: 687 VTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKFV-DGEW 745
           V  I     F+ Q +++G +L +L  ++       PP    Y P  G+ C A+F  D +W
Sbjct: 500 VAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFY-PAIGDICCAQFSEDDQW 558

Query: 746 YRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQ 802
           YRA V    S   + V Y+DYGN E+L   RL  + P      LP QA +   A ++
Sbjct: 559 YRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLE--LPMQAIKCVLAGVK 613



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 5/97 (5%)

Query: 709 KLMENMRNDIASH--PPVEGSYAPRRGEFCIAKFV-DGEWYRARVEKVESPAKIHVFYID 765
           K + ++   +A H    +   +    G+ C A F  DG WYRA V+++     + V ++D
Sbjct: 740 KKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVD 799

Query: 766 YGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQ 802
           YGN E + +  L  +S  F    LP Q      A IQ
Sbjct: 800 YGNIEEVTADELRMISSTFLN--LPFQGIRCQLADIQ 834



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 27/59 (45%), Positives = 31/59 (52%), Gaps = 6/59 (10%)

Query: 720  SHPPVEGSYAPRRGEFCIAKFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRL 777
            S PP    Y PR G+ C AK+  D  WYRA V    S   + V Y DYGN E LP  R+
Sbjct: 985  SRPP----YRPRIGDACCAKYTSDDFWYRAVVLGT-SDTDVEVLYADYGNIETLPLCRV 1038


>gi|94421471 ring finger protein 17 [Homo sapiens]
          Length = 1623

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 73/317 (23%), Positives = 131/317 (41%), Gaps = 33/317 (10%)

Query: 569 GLVQEGEPFSEEATLFTKELVLQR-----EVEVEVESMDKAGNFIGWLHIDGANLSVLLV 623
           GL+++ +P ++  +L  K++V Q      E E +VE +    N    + +      VL+V
Sbjct: 564 GLLKDIQPLAQPCSL--KDIVPQNSNEGWEEEAKVEFLKMVNNKAVSMKVFREEDGVLIV 621

Query: 624 EHALSKVH-FTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKERSASY 682
           +      +  +++     +  L   E AK K + + +H+E+       P +  KE +   
Sbjct: 622 DLQKPPPNKISSDMPVSLRDALVFMELAKFKSQSLRSHFEKNTTLHYHPPILPKEMTDV- 680

Query: 683 KPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSY-APRRGEFCIAKFV 741
             V V  I     FY+Q +E G  +  L++ +     S          P + + C+AKF 
Sbjct: 681 -SVTVCHINSPGDFYLQLIE-GLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKFE 738

Query: 742 DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFI 801
           DG WYRA+V  +    ++ V Y+D+GN   +    +  +   F     P +A +   A+I
Sbjct: 739 DGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLN--APEKAIKCKLAYI 796

Query: 802 QVPQ-------------DDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHVTLQFADSK 848
           +  +             ++ A+   +   V  I     LL     S G P +T    + +
Sbjct: 797 EPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTTSINDQ 856

Query: 849 GDVGLGLVKEGLVMVEV 865
                 LVKEGL   E+
Sbjct: 857 ------LVKEGLASYEI 867



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 67/333 (20%), Positives = 137/333 (41%), Gaps = 60/333 (18%)

Query: 574  GEPFSEEATLFTKELVLQREVEVEVESMDKAGNFIGW------LHIDGANLSVLLVEHAL 627
            G  +  +A    ++L+ +R+V++ +  + K      W      L+ DG +LS  +  +  
Sbjct: 1300 GNVWQPDAIEVLQQLLSKRQVDIHIMELPKNP----WEKLSIHLYFDGMSLSYFMAYYKY 1355

Query: 628  SKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQ-PVEEVMPVLEEKERSASYKP-- 684
                 T E     K    ++   K ++E+    +EE    E   P+L     S+   P  
Sbjct: 1356 CTSEHTEEM---LKEKPRSDHDKKYEEEQWEIRFEELLSAETDTPLLPPYLSSSLPSPGE 1412

Query: 685  VFVTEIT-----DDLHFYVQDVETGTQ--------------------LEKLMENMRNDIA 719
            ++  ++      ++++  +  +ET  Q                    L++ ++ +   + 
Sbjct: 1413 LYAVQVKHVVSPNEVYICLDSIETSNQSNQHSDTDDSGVSGESESESLDEALQRVNKKVE 1472

Query: 720  SHPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVE--SPAKIHVFYIDYGNREVLPSTRL 777
            + PP+      R    C+A++ DG WYRA++  ++  +P  I V ++DYG+   L   RL
Sbjct: 1473 ALPPLTDF---RTEMPCLAEYDDGLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLTLNRL 1529

Query: 778  GTLSPAFSTRVLPAQATEYAFAFIQVPQDDDART----------DAVDSVVRDIQNTQCL 827
              + P+   R  PA+A +   A  + P  D   T          +A+ +++  +Q  Q  
Sbjct: 1530 CQI-PSHLMR-YPARAIKVLLAGFKPPLRDLGETRIPYCPKWSMEALWAMIDCLQGKQ-- 1585

Query: 828  LNVEHLSAGCPHVTLQFADSKGDVGLGLVKEGL 860
            L    ++     +   + D +  V + LV+ GL
Sbjct: 1586 LYAVSMAPAPEQIVTLYDDEQHPVHMPLVEMGL 1618



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 37/124 (29%), Positives = 54/124 (43%), Gaps = 10/124 (8%)

Query: 663  EQPVEEVMPVLEEKERSASYKPVFVTEIT--DDLHFYVQDVETGTQLEKLME----NMRN 716
            EQ V E    + E   +  YKP  +  +   +     V D  T   + KL E     M N
Sbjct: 1153 EQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVVPKLSEFELIKMTN 1212

Query: 717  DIASHPPVEGSYAP---RRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLP 773
            +I S+    G   P   ++GE C  +  D  WYR +V +V   A + V Y+D+G  E +P
Sbjct: 1213 EIQSNLKCLGLLEPYFWKKGEACAVRGSDTLWYRGKVMEVVGGA-VRVQYLDHGFTEKIP 1271

Query: 774  STRL 777
               L
Sbjct: 1272 QCHL 1275



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 30/129 (23%), Positives = 52/129 (40%), Gaps = 28/129 (21%)

Query: 666 VEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQ---DVETGTQLEKLMENMRNDIASHP 722
           +EE++    E    +S + VFV+ + D  HFY++    ++    LEK +    N  +   
Sbjct: 404 IEEII----EDNVESSAELVFVSHVIDPCHFYIRKYSQIKDAKVLEKKVNEFCNRSSHLD 459

Query: 723 PVEGSYAPRRGEFCIAKFVDGEWYRARVEK-------------------VESPAKIHVFY 763
           P +      R    ++   +G W R  + +                   V   A I +F 
Sbjct: 460 PSDILELGAR--IFVSSIKNGMWCRGTITELIPIEGRNTRKPCSPTRLFVHEVALIQIFM 517

Query: 764 IDYGNREVL 772
           +D+GN EVL
Sbjct: 518 VDFGNSEVL 526


>gi|58197558 tudor domain containing 6 [Homo sapiens]
          Length = 2096

 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 4/127 (3%)

Query: 685  VFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKFV-DG 743
            V+V+ I D   FYVQ +E   ++  L E + N + + P        +RG+   A F  D 
Sbjct: 1309 VYVSHINDLSDFYVQLIEDEAEISHLSERL-NSVKTRPEYYVGPPLQRGDMICAVFPEDN 1367

Query: 744  EWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQV 803
             WYRA +++ +    + V +IDYGN  V+ + ++G L       +LP      +    +V
Sbjct: 1368 LWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLD--LVNAILPGLCIHCSLQGFEV 1425

Query: 804  PQDDDAR 810
            P + +++
Sbjct: 1426 PDNKNSK 1432



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 41/135 (30%), Positives = 63/135 (46%), Gaps = 27/135 (20%)

Query: 685  VFVTEITDDLHFYVQDVETG----------TQLEKLMENMRNDIASHPPVEGSYAPRRGE 734
            V++T I D   FY Q               TQL K++ N++    +            G 
Sbjct: 990  VYITHIDDPWTFYCQLARNANILEQLSCSITQLSKVLLNLKTSPLNP-----------GT 1038

Query: 735  FCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTL-SPAFSTRVLPAQA 793
             C+AK+ DG WYR  V + E P K  VF++D+GN  V+ S  L  + S A+   +LP QA
Sbjct: 1039 LCLAKYTDGNWYRGIVIEKE-PKK--VFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQA 1095

Query: 794  TEYAFAFI--QVPQD 806
               + + I   +P++
Sbjct: 1096 VRCSLSDIPDHIPEE 1110



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 54/244 (22%), Positives = 98/244 (40%), Gaps = 25/244 (10%)

Query: 567 LPGLVQEGEPFSEEATLFTKELVLQREVEVEVESMDKAGN--FIGWLHIDGANLSVLLVE 624
           L GL   G  +S       K L+L + V  ++E      +  ++     DG NL+ +   
Sbjct: 378 LYGLWDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYYVSLYGEDGINLNRV--- 434

Query: 625 HALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEV-----MPVLEE-KER 678
                  F  +       +L ++   +++ E       + P EEV     +P L   + +
Sbjct: 435 -------FGVQSCCLADRVLQSQATEEEEPE---TSQSQSPAEEVDEEISLPALRSIRLK 484

Query: 679 SASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYA-PRRGEFCI 737
             ++    V  + +   F+++  +      KLM  M    +S   ++G    P   + C 
Sbjct: 485 MNAFYDAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCC 544

Query: 738 AKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYA 797
            K+ +  +YRA V K++  + + VF +D GN E +    +  L P F  R LP  A +  
Sbjct: 545 VKWKENGYYRAIVTKLDDKS-VDVFLVDRGNSENVDWYDVRMLLPQF--RQLPILAVKCT 601

Query: 798 FAFI 801
            A I
Sbjct: 602 LADI 605



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 16/50 (32%), Positives = 32/50 (64%), Gaps = 1/50 (2%)

Query: 736 CIAK-FVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAF 784
           C+AK  V+ +W RA +  ++S   ++V ++DYG+RE++    + ++S  F
Sbjct: 823 CLAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEF 872



 Score = 35.0 bits (79), Expect = 0.32
 Identities = 17/53 (32%), Positives = 29/53 (54%), Gaps = 1/53 (1%)

Query: 733 GEFCIAKFVDGEWYRARVEKVESPAK-IHVFYIDYGNREVLPSTRLGTLSPAF 784
           G  C +  +DG WYRA + +   P +   V ++DYG +E++  + L  L P +
Sbjct: 314 GSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEY 366


>gi|145312259 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 64/265 (24%), Positives = 112/265 (42%), Gaps = 23/265 (8%)

Query: 643 LLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKERSAS-----YKPVFVTEITDDLHFY 697
           ++S E + ++  +  +   E Q + E MP+ E      S     Y  V+V+      HF+
Sbjct: 264 VVSKEGSWEKPSDDSFQKSEAQAIPE-MPMFEIPSPDFSFHADEYLEVYVSASEHPNHFW 322

Query: 698 VQDVETGT-QLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKF-VDGEWYRARVEKVES 755
           +Q V + + QL+KL+  M     +  P +       G+   A    +G WYRARV     
Sbjct: 323 IQIVGSRSLQLDKLVNEMTQHYENSVPED--LTVHVGDIVAAPLPTNGSWYRARVLGTLE 380

Query: 756 PAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVD 815
              + ++++D+G+    P   L  L   F +  LP QA E + A I  P  D    +A+D
Sbjct: 381 NGNLDLYFVDFGDNGDCPLKDLRALRSDFLS--LPFQAIECSLARI-APSGDQWEEEALD 437

Query: 816 SVVRDIQNTQCLLNVEHLS-------AGCPHVTLQFADS--KGDVGLGLVKEGLVMVEVR 866
              R          V  +S       +  P + L    +  K D+GL LV +G   +E+ 
Sbjct: 438 EFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYA-IELP 496

Query: 867 KEKQFQKVITEYLNAQESAKSARLN 891
           ++ +  + + + L    +   A L+
Sbjct: 497 EDIEENRAVPDMLKDMATETDASLS 521


>gi|145312246 tudor and KH domain containing isoform b [Homo
           sapiens]
          Length = 516

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 64/265 (24%), Positives = 112/265 (42%), Gaps = 23/265 (8%)

Query: 643 LLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKERSAS-----YKPVFVTEITDDLHFY 697
           ++S E + ++  +  +   E Q + E MP+ E      S     Y  V+V+      HF+
Sbjct: 219 VVSKEGSWEKPSDDSFQKSEAQAIPE-MPMFEIPSPDFSFHADEYLEVYVSASEHPNHFW 277

Query: 698 VQDVETGT-QLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKF-VDGEWYRARVEKVES 755
           +Q V + + QL+KL+  M     +  P +       G+   A    +G WYRARV     
Sbjct: 278 IQIVGSRSLQLDKLVNEMTQHYENSVPED--LTVHVGDIVAAPLPTNGSWYRARVLGTLE 335

Query: 756 PAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVD 815
              + ++++D+G+    P   L  L   F +  LP QA E + A I  P  D    +A+D
Sbjct: 336 NGNLDLYFVDFGDNGDCPLKDLRALRSDFLS--LPFQAIECSLARI-APSGDQWEEEALD 392

Query: 816 SVVRDIQNTQCLLNVEHLS-------AGCPHVTLQFADS--KGDVGLGLVKEGLVMVEVR 866
              R          V  +S       +  P + L    +  K D+GL LV +G   +E+ 
Sbjct: 393 EFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYA-IELP 451

Query: 867 KEKQFQKVITEYLNAQESAKSARLN 891
           ++ +  + + + L    +   A L+
Sbjct: 452 EDIEENRAVPDMLKDMATETDASLS 476


>gi|145312270 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 64/265 (24%), Positives = 112/265 (42%), Gaps = 23/265 (8%)

Query: 643 LLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKERSAS-----YKPVFVTEITDDLHFY 697
           ++S E + ++  +  +   E Q + E MP+ E      S     Y  V+V+      HF+
Sbjct: 264 VVSKEGSWEKPSDDSFQKSEAQAIPE-MPMFEIPSPDFSFHADEYLEVYVSASEHPNHFW 322

Query: 698 VQDVETGT-QLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKF-VDGEWYRARVEKVES 755
           +Q V + + QL+KL+  M     +  P +       G+   A    +G WYRARV     
Sbjct: 323 IQIVGSRSLQLDKLVNEMTQHYENSVPED--LTVHVGDIVAAPLPTNGSWYRARVLGTLE 380

Query: 756 PAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVD 815
              + ++++D+G+    P   L  L   F +  LP QA E + A I  P  D    +A+D
Sbjct: 381 NGNLDLYFVDFGDNGDCPLKDLRALRSDFLS--LPFQAIECSLARI-APSGDQWEEEALD 437

Query: 816 SVVRDIQNTQCLLNVEHLS-------AGCPHVTLQFADS--KGDVGLGLVKEGLVMVEVR 866
              R          V  +S       +  P + L    +  K D+GL LV +G   +E+ 
Sbjct: 438 EFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYA-IELP 496

Query: 867 KEKQFQKVITEYLNAQESAKSARLN 891
           ++ +  + + + L    +   A L+
Sbjct: 497 EDIEENRAVPDMLKDMATETDASLS 521


>gi|145312256 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 64/265 (24%), Positives = 112/265 (42%), Gaps = 23/265 (8%)

Query: 643 LLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKERSAS-----YKPVFVTEITDDLHFY 697
           ++S E + ++  +  +   E Q + E MP+ E      S     Y  V+V+      HF+
Sbjct: 264 VVSKEGSWEKPSDDSFQKSEAQAIPE-MPMFEIPSPDFSFHADEYLEVYVSASEHPNHFW 322

Query: 698 VQDVETGT-QLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKF-VDGEWYRARVEKVES 755
           +Q V + + QL+KL+  M     +  P +       G+   A    +G WYRARV     
Sbjct: 323 IQIVGSRSLQLDKLVNEMTQHYENSVPED--LTVHVGDIVAAPLPTNGSWYRARVLGTLE 380

Query: 756 PAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVD 815
              + ++++D+G+    P   L  L   F +  LP QA E + A I  P  D    +A+D
Sbjct: 381 NGNLDLYFVDFGDNGDCPLKDLRALRSDFLS--LPFQAIECSLARI-APSGDQWEEEALD 437

Query: 816 SVVRDIQNTQCLLNVEHLS-------AGCPHVTLQFADS--KGDVGLGLVKEGLVMVEVR 866
              R          V  +S       +  P + L    +  K D+GL LV +G   +E+ 
Sbjct: 438 EFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYA-IELP 496

Query: 867 KEKQFQKVITEYLNAQESAKSARLN 891
           ++ +  + + + L    +   A L+
Sbjct: 497 EDIEENRAVPDMLKDMATETDASLS 521


>gi|169163653 PREDICTED: similar to tudor domain containing 1 [Homo
           sapiens]
          Length = 2080

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 52/208 (25%), Positives = 98/208 (47%), Gaps = 12/208 (5%)

Query: 686 FVTEITDDLHFYVQDVETGTQLEKLMENMRN--DIASHPPVEGSYAPRRGEFCIAKFV-D 742
           F+  + +  +F+V+  +   + +++M+N+    D+  +  +     P  G FC A++  D
Sbjct: 633 FIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCENDEMI-LRKPEPGLFCCARYSKD 691

Query: 743 GEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQ 802
             +YRA + ++    KI+V+++DYGN + +P   +  L P F    LPA A   + A I 
Sbjct: 692 RRFYRAVITEING-YKINVYFLDYGNTDSIPFFDVKILLPEFCE--LPALAMCCSLAHI- 747

Query: 803 VPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHVTLQFADSKG--DVGLGLVKEGL 860
            P +D     A+D   + + N   LL V         V +Q  ++    DV   +++ G 
Sbjct: 748 FPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSVEASENIDVISLMLQAGY 807

Query: 861 VMVEVRKEKQFQKVITEY--LNAQESAK 886
                 + + F K ++EY  LN++   K
Sbjct: 808 AEYFQVELEYFPKSVSEYSMLNSESKNK 835



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 27/119 (22%), Positives = 56/119 (47%)

Query: 666 VEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVE 725
           ++ V+  L+      S + V V+       FY Q ++   +LE L  +M     +     
Sbjct: 372 IQHVLDKLQPSLSVGSTESVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQET 431

Query: 726 GSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAF 784
                  G  C+A+  +G+W+R  ++++  P ++ ++++DYG+ E +PS  +  L   F
Sbjct: 432 SPTCDNFGLLCVARRRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDF 490



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 7/107 (6%)

Query: 681  SYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDI--ASHPPVEGSYAPRRGEFCIA 738
            S + V+++ I     FY Q       LE +   +   +   + P     Y   +   CI+
Sbjct: 1111 SEEEVYISHIYSPQKFYCQLGRNNKDLEMIETKITESVNLQNFP----KYDSNKMRVCIS 1166

Query: 739  KFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAF 784
            K+V DG  YRA     +S ++  V+++D+GN++++    L  +S  F
Sbjct: 1167 KYVEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQF 1213



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 29/129 (22%), Positives = 62/129 (48%), Gaps = 6/129 (4%)

Query: 663  EQPVEEVMPVLEEKERSASYKPV----FVTEITDDLHFYVQDVETGTQLEKLMENMRNDI 718
            + P + + P +++  +   Y       +V+ I++  +F++Q  E  + + +L + + N  
Sbjct: 1419 QNPYDLIRPQIKDLPQPQIYLNAKVKGYVSNISNPANFHIQLAENESVIIRLADAL-NAT 1477

Query: 719  ASHPPVEGSYAPRRGEFCIAKFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRL 777
            A       S  P  G+  +A++  D   YRA ++K+       V +IDYGN  ++ ++++
Sbjct: 1478 ARRLRERKSVKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKI 1537

Query: 778  GTLSPAFST 786
              L   F T
Sbjct: 1538 YELQREFLT 1546



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 3/63 (4%)

Query: 732  RGEFCIAKFVDG-EWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLP 790
            +G  C+AK  +  +W+R++VE+     K+ VF +D G  E++P      LS     R +P
Sbjct: 1723 KGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSN--EIRNIP 1780

Query: 791  AQA 793
             QA
Sbjct: 1781 RQA 1783


>gi|169164192 PREDICTED: similar to tudor domain containing 1 [Homo
           sapiens]
          Length = 2080

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 52/208 (25%), Positives = 98/208 (47%), Gaps = 12/208 (5%)

Query: 686 FVTEITDDLHFYVQDVETGTQLEKLMENMRN--DIASHPPVEGSYAPRRGEFCIAKFV-D 742
           F+  + +  +F+V+  +   + +++M+N+    D+  +  +     P  G FC A++  D
Sbjct: 633 FIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCENDEMI-LRKPEPGLFCCARYSKD 691

Query: 743 GEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQ 802
             +YRA + ++    KI+V+++DYGN + +P   +  L P F    LPA A   + A I 
Sbjct: 692 RRFYRAVITEING-YKINVYFLDYGNTDSIPFFDVKILLPEFCE--LPALAMCCSLAHI- 747

Query: 803 VPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHVTLQFADSKG--DVGLGLVKEGL 860
            P +D     A+D   + + N   LL V         V +Q  ++    DV   +++ G 
Sbjct: 748 FPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSVEASENIDVISLMLQAGY 807

Query: 861 VMVEVRKEKQFQKVITEY--LNAQESAK 886
                 + + F K ++EY  LN++   K
Sbjct: 808 AEYFQVELEYFPKSVSEYSMLNSESKNK 835



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 27/119 (22%), Positives = 56/119 (47%)

Query: 666 VEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVE 725
           ++ V+  L+      S + V V+       FY Q ++   +LE L  +M     +     
Sbjct: 372 IQHVLDKLQPSLSVGSTESVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQET 431

Query: 726 GSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAF 784
                  G  C+A+  +G+W+R  ++++  P ++ ++++DYG+ E +PS  +  L   F
Sbjct: 432 SPTCDNFGLLCVARRRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDF 490



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 7/107 (6%)

Query: 681  SYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDI--ASHPPVEGSYAPRRGEFCIA 738
            S + V+++ I     FY Q       LE +   +   +   + P     Y   +   CI+
Sbjct: 1111 SEEEVYISHIYSPQKFYCQLGRNNKDLEMIETKITESVNLQNFP----KYDSNKMRVCIS 1166

Query: 739  KFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAF 784
            K+V DG  YRA     +S ++  V+++D+GN++++    L  +S  F
Sbjct: 1167 KYVEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQF 1213



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 29/129 (22%), Positives = 62/129 (48%), Gaps = 6/129 (4%)

Query: 663  EQPVEEVMPVLEEKERSASYKPV----FVTEITDDLHFYVQDVETGTQLEKLMENMRNDI 718
            + P + + P +++  +   Y       +V+ I++  +F++Q  E  + + +L + + N  
Sbjct: 1419 QNPYDLIRPQIKDLPQPQIYLNAKVKGYVSNISNPANFHIQLAENESVIIRLADAL-NAT 1477

Query: 719  ASHPPVEGSYAPRRGEFCIAKFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRL 777
            A       S  P  G+  +A++  D   YRA ++K+       V +IDYGN  ++ ++++
Sbjct: 1478 ARRLRERKSVKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKI 1537

Query: 778  GTLSPAFST 786
              L   F T
Sbjct: 1538 YELQREFLT 1546



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 3/63 (4%)

Query: 732  RGEFCIAKFVDG-EWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLP 790
            +G  C+AK  +  +W+R++VE+     K+ VF +D G  E++P      LS     R +P
Sbjct: 1723 KGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSN--EIRNIP 1780

Query: 791  AQA 793
             QA
Sbjct: 1781 RQA 1783


>gi|169163210 PREDICTED: similar to tudor domain containing 1 [Homo
           sapiens]
          Length = 2080

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 52/208 (25%), Positives = 98/208 (47%), Gaps = 12/208 (5%)

Query: 686 FVTEITDDLHFYVQDVETGTQLEKLMENMRN--DIASHPPVEGSYAPRRGEFCIAKFV-D 742
           F+  + +  +F+V+  +   + +++M+N+    D+  +  +     P  G FC A++  D
Sbjct: 633 FIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCENDEMI-LRKPEPGLFCCARYSKD 691

Query: 743 GEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQ 802
             +YRA + ++    KI+V+++DYGN + +P   +  L P F    LPA A   + A I 
Sbjct: 692 RRFYRAVITEING-YKINVYFLDYGNTDSIPFFDVKILLPEFCE--LPALAMCCSLAHI- 747

Query: 803 VPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHVTLQFADSKG--DVGLGLVKEGL 860
            P +D     A+D   + + N   LL V         V +Q  ++    DV   +++ G 
Sbjct: 748 FPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSVEASENIDVISLMLQAGY 807

Query: 861 VMVEVRKEKQFQKVITEY--LNAQESAK 886
                 + + F K ++EY  LN++   K
Sbjct: 808 AEYFQVELEYFPKSVSEYSMLNSESKNK 835



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 27/119 (22%), Positives = 56/119 (47%)

Query: 666 VEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVE 725
           ++ V+  L+      S + V V+       FY Q ++   +LE L  +M     +     
Sbjct: 372 IQHVLDKLQPSLSVGSTESVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQET 431

Query: 726 GSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAF 784
                  G  C+A+  +G+W+R  ++++  P ++ ++++DYG+ E +PS  +  L   F
Sbjct: 432 SPTCDNFGLLCVARRRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDF 490



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 7/107 (6%)

Query: 681  SYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDI--ASHPPVEGSYAPRRGEFCIA 738
            S + V+++ I     FY Q       LE +   +   +   + P     Y   +   CI+
Sbjct: 1111 SEEEVYISHIYSPQKFYCQLGRNNKDLEMIETKITESVNLQNFP----KYDSNKMRVCIS 1166

Query: 739  KFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAF 784
            K+V DG  YRA     +S ++  V+++D+GN++++    L  +S  F
Sbjct: 1167 KYVEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQF 1213



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 29/129 (22%), Positives = 62/129 (48%), Gaps = 6/129 (4%)

Query: 663  EQPVEEVMPVLEEKERSASYKPV----FVTEITDDLHFYVQDVETGTQLEKLMENMRNDI 718
            + P + + P +++  +   Y       +V+ I++  +F++Q  E  + + +L + + N  
Sbjct: 1419 QNPYDLIRPQIKDLPQPQIYLNAKVKGYVSNISNPANFHIQLAENESVIIRLADAL-NAT 1477

Query: 719  ASHPPVEGSYAPRRGEFCIAKFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRL 777
            A       S  P  G+  +A++  D   YRA ++K+       V +IDYGN  ++ ++++
Sbjct: 1478 ARRLRERKSVKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKI 1537

Query: 778  GTLSPAFST 786
              L   F T
Sbjct: 1538 YELQREFLT 1546



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 3/63 (4%)

Query: 732  RGEFCIAKFVDG-EWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLP 790
            +G  C+AK  +  +W+R++VE+     K+ VF +D G  E++P      LS     R +P
Sbjct: 1723 KGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSN--EIRNIP 1780

Query: 791  AQA 793
             QA
Sbjct: 1781 RQA 1783


>gi|112293287 tudor domain containing 7 [Homo sapiens]
          Length = 1098

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 40/149 (26%), Positives = 67/149 (44%), Gaps = 4/149 (2%)

Query: 669 VMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSY 728
           V P++   E S S   V ++   + +  YV    +  Q E + + M+   + +P +    
Sbjct: 454 VPPLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQ-ELMEDEMKEYYSKNPKITPVQ 512

Query: 729 APRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRV 788
           A   G+       +  W RA+V   E   KI V Y+DYG  E +  ++   L+P F +  
Sbjct: 513 AVNVGQLLAVNAEEDAWLRAQVISTEEN-KIKVCYVDYGFSENVEKSKAYKLNPKFCS-- 569

Query: 789 LPAQATEYAFAFIQVPQDDDARTDAVDSV 817
           L  QAT+   A ++V  DD      V+S+
Sbjct: 570 LSFQATKCKLAGLEVLSDDPDLVKVVESL 598



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 35/152 (23%), Positives = 65/152 (42%), Gaps = 6/152 (3%)

Query: 654  KEKVWAHYEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMEN 713
            K+ +  H      EE+ P +    +   +  V+V       +F +Q  +   +LE LME 
Sbjct: 886  KKSMVDHTSAFSTEELPPPVH-LSKPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEE 944

Query: 714  MRNDIASHPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLP 773
            M   I  +   E  +     +   A  V+ +W+R  ++ + +   + V+ +DYG  E++ 
Sbjct: 945  M---ILYYSVSEERHIAVEKDQVYAAKVENKWHRVLLKGILTNGLVSVYELDYGKHELVN 1001

Query: 774  STRLGTLSPAFSTRVLPAQATEYAFAFIQVPQ 805
              ++  L   F  R LP QA     A ++  Q
Sbjct: 1002 IRKVQPLVDMF--RKLPFQAVTAQLAGVKCNQ 1031


>gi|40255178 tudor domain containing 5 [Homo sapiens]
          Length = 981

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 9/125 (7%)

Query: 685 VFVTEITDDLHFYVQ--DVETGTQLEKLMENMR----NDIASHPPVEGSYAPRRGEFCIA 738
           VFV  I     FY++    ++   LE +M  MR    N + S   V      + G  C  
Sbjct: 475 VFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCV 534

Query: 739 KFVDGEW-YRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYA 797
           +  + +W YR  + +V    ++ VFY D+GN  ++  + L  L   ++   LPAQA   +
Sbjct: 535 RISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTK--LPAQAIPCS 592

Query: 798 FAFIQ 802
            A+++
Sbjct: 593 LAWVR 597


>gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]
          Length = 903

 Score = 40.8 bits (94), Expect = 0.006
 Identities = 37/130 (28%), Positives = 55/130 (42%), Gaps = 7/130 (5%)

Query: 736 CIAKFVDGEWYRAR-VEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQAT 794
           C A   DG W+RA+ V   E   ++ + Y+DYG  + +    L  +   F T  LP Q  
Sbjct: 765 CAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVT--LPFQGA 822

Query: 795 EYAFAFIQVPQDDDARTDAVDSVVRDIQ-NTQCLLNVEHLS-AGCPHVTL--QFADSKGD 850
           E     +    DDD  +   D+ + ++  NT  L  V   S  G P + L     D    
Sbjct: 823 EVLLDSVMPLSDDDQFSPEADAAMSEMTGNTALLAQVTSYSPTGLPLIQLWSVVGDEVVL 882

Query: 851 VGLGLVKEGL 860
           +   LV+ GL
Sbjct: 883 INRSLVERGL 892


>gi|170784859 serine/threonine kinase 31 isoform b [Homo sapiens]
          Length = 996

 Score = 38.5 bits (88), Expect = 0.029
 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 7/103 (6%)

Query: 673 LEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRR 732
           ++E       + V  + I D + F+ Q +     + K+  ++         V G+  P +
Sbjct: 1   MDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDPNK 60

Query: 733 ---GEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVL 772
              G F      D  WYR +V K+ S  K  V YIDYGN E+L
Sbjct: 61  IYGGLFS----EDQCWYRCKVLKIISVEKCLVRYIDYGNTEIL 99


>gi|14602443 serine/threonine kinase 31 isoform a [Homo sapiens]
          Length = 1019

 Score = 38.5 bits (88), Expect = 0.029
 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 7/103 (6%)

Query: 673 LEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRR 732
           ++E       + V  + I D + F+ Q +     + K+  ++         V G+  P +
Sbjct: 24  MDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDPNK 83

Query: 733 ---GEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVL 772
              G F      D  WYR +V K+ S  K  V YIDYGN E+L
Sbjct: 84  IYGGLFS----EDQCWYRCKVLKIISVEKCLVRYIDYGNTEIL 122


>gi|170784856 serine/threonine kinase 31 isoform b [Homo sapiens]
          Length = 996

 Score = 38.5 bits (88), Expect = 0.029
 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 7/103 (6%)

Query: 673 LEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRR 732
           ++E       + V  + I D + F+ Q +     + K+  ++         V G+  P +
Sbjct: 1   MDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDPNK 60

Query: 733 ---GEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVL 772
              G F      D  WYR +V K+ S  K  V YIDYGN E+L
Sbjct: 61  IYGGLFS----EDQCWYRCKVLKIISVEKCLVRYIDYGNTEIL 99


>gi|166851804 tudor domain containing 9 [Homo sapiens]
          Length = 1382

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 36/154 (23%), Positives = 69/154 (44%), Gaps = 12/154 (7%)

Query: 650  AKQKKEKVWAHYEEQPVEEVMPVLEEKERSASYKPVF----VTEITDDLHFYVQDVETGT 705
            +K +  +V   +++Q V+ +       +RS +   +     VTE+ +  HF+   ++   
Sbjct: 863  SKLRNTRVNVDFQKQTVDPMQVSFNTSDRSQTVTDLLLTIDVTEVVEVGHFWGYRIDENN 922

Query: 706  QLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKFVDGE---WYRARVEKVESPAKIHVF 762
               ++++ +  +I     V     P     C+A F D +   ++RA+V  V S     VF
Sbjct: 923  S--EILKKLTAEINQLTLVPLPTHPHPDLVCLAPFADFDKQRYFRAQVLYV-SGNSAEVF 979

Query: 763  YIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEY 796
            ++DYGN+  +    L  +   F    LP QA E+
Sbjct: 980  FVDYGNKSHVDLHLLMEIPCQFLE--LPFQALEF 1011


>gi|28416940 Shwachman-Bodian-Diamond syndrome protein [Homo
           sapiens]
          Length = 250

 Score = 35.0 bits (79), Expect = 0.32
 Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 5/84 (5%)

Query: 619 SVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKER 678
           +V+L+E A+  +H++ + +   K    A E  KQ KEK+        +  ++PV E K+ 
Sbjct: 129 TVILIERAMKDIHYSVKTNKSTKQ--QALEVIKQLKEKMKIERAHMRLRFILPVNEGKKL 186

Query: 679 SASYKPVFVTEITDDLHFYVQDVE 702
               KP+     ++D   Y Q +E
Sbjct: 187 KEKLKPLIKVIESED---YGQQLE 207


>gi|189571674 cadherin-like 23 isoform 1 precursor [Homo sapiens]
          Length = 3354

 Score = 33.1 bits (74), Expect = 1.2
 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 2/67 (2%)

Query: 447  GINIAEALVSKGLATVIRYRQDDDQRS--SHYDELLAAEARAIKNGKGLHSKKEVPIHRV 504
            GI++        LAT +    ++DQ+      + L AAEA A +      S K  P+H++
Sbjct: 3281 GIHVVHGSTGTLLATDLNSLPEEDQKGLGRSLETLTAAEATAFERNARTESAKSTPLHKL 3340

Query: 505  ADISGDT 511
             D+  +T
Sbjct: 3341 RDVIMET 3347


>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
          Length = 1243

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 18/65 (27%)

Query: 37 GQPRGGPPPERQINLS-----NIRAGNLARRA-------------AATQPDAKDTPDEPW 78
          GQPR GPPP R    S       R+  L+RR+             A+  PD  D PD   
Sbjct: 32 GQPRLGPPPRRARRFSGKAEPRPRSSRLSRRSSVDLGLLSSWSLPASPAPDPPDPPDSAG 91

Query: 79 AFPAR 83
            PAR
Sbjct: 92 PGPAR 96


>gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]
          Length = 2156

 Score = 31.6 bits (70), Expect = 3.5
 Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 8/100 (8%)

Query: 595  EVEVESMDKAGNFIGWLHIDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKK 654
            E +V S++ A  ++  LH +   LS   +    +K H  AE+S   K L+  E    +K+
Sbjct: 1006 ETQVGSLNDA--YLVPLH-EHCTLSQSAINDHNTKSHIAAEKSGPEKKLVYQEINLARKR 1062

Query: 655  EKVWAHYEEQPVEE-----VMPVLEEKERSASYKPVFVTE 689
            + V A  +  P+EE     ++PVL   +  AS   +  T+
Sbjct: 1063 QSVEAAIQVDPIEEETPKDLLPVLMLHQLQASVPGIHKTQ 1102


>gi|9910266 kinesin family member 15 [Homo sapiens]
          Length = 1388

 Score = 30.8 bits (68), Expect = 6.0
 Identities = 31/117 (26%), Positives = 48/117 (41%), Gaps = 24/117 (20%)

Query: 625  HALSKVHFTAERSSYYKSLLSA--EEAAK-------------QKKEKVWA-----HYEEQ 664
            HA  +++   E S  +  LL +  EE  K             QKKE+V       +++ +
Sbjct: 1067 HATEQLNMLTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMR 1126

Query: 665  PVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETG----TQLEKLMENMRND 717
             +E VM    E  +S    P F T +   L    Q++E G    T LE L+  +  D
Sbjct: 1127 QLEHVMDSAAEDPQSPKTPPHFQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNED 1183


>gi|148806891 hypothetical protein LOC54906 [Homo sapiens]
          Length = 2430

 Score = 30.8 bits (68), Expect = 6.0
 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 506  DISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRLKL-YLPKETCLITFLLAGIE 559
            D+SG+    + +LPF  R+   E ++  V +   +KL  + KE C  TFL   +E
Sbjct: 2137 DVSGEATAQEMYLPFPGRSASYEDIIIDVCTNLHVKLRSVVKEACKSTFLFYLVE 2191


>gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens]
          Length = 1621

 Score = 30.4 bits (67), Expect = 7.8
 Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 465  YRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRA 524
            Y Q  +  S+ +D      A       GL    +VP   VA   G  + +   +P  +RA
Sbjct: 1448 YSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKG--KPSSDTVPKPKRA 1505

Query: 525  GRSEAVVEYVFSGSRLKLYLPKET 548
             + + VVE V S S  +  +PK+T
Sbjct: 1506 PKQKKVVEAVNSDSDSEFGIPKKT 1529


>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
          Length = 1395

 Score = 30.4 bits (67), Expect = 7.8
 Identities = 33/106 (31%), Positives = 50/106 (47%), Gaps = 18/106 (16%)

Query: 576 PFSEEATLFTKELVLQREVEVEVE-------SMDKAGNFIGWLHIDGANLSVL--LVEHA 626
           P +EEA+LF K LVL+ E  +E E       S+ K  N     H + + L  L  L E +
Sbjct: 146 PNTEEASLFRKPLVLKEEPTIEDETLINKSLSLKKCSN-----HEEVSLLEKLQPLQEES 200

Query: 627 LSKVHFTAERSSYYKSLLSAEEAAKQK----KEKVWAHYEEQPVEE 668
            S   F  E  ++ K+  + E A  +K    K+K+ A   +Q  +E
Sbjct: 201 DSDDAFVIEPMTFKKTHKTEEAAITKKTLSLKKKMCASQRKQSCQE 246


>gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo
           sapiens]
          Length = 1235

 Score = 30.4 bits (67), Expect = 7.8
 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 8/95 (8%)

Query: 675 EKERSASYKPVFVTEITDDLHFYVQDV-ETGTQLEKL--MENMRNDIASHPPVEGSYAPR 731
           + E S  + P F  E++ D+ F+ +    +G  LE L   + +R ++ S   V  S+   
Sbjct: 725 DTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVG 784

Query: 732 RGEFCIA-----KFVDGEWYRARVEKVESPAKIHV 761
            G F I+      F D +W+  RVE+    A + V
Sbjct: 785 NGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQV 819


>gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo
           sapiens]
          Length = 1308

 Score = 30.4 bits (67), Expect = 7.8
 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 8/95 (8%)

Query: 675 EKERSASYKPVFVTEITDDLHFYVQDV-ETGTQLEKL--MENMRNDIASHPPVEGSYAPR 731
           + E S  + P F  E++ D+ F+ +    +G  LE L   + +R ++ S   V  S+   
Sbjct: 798 DTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVG 857

Query: 732 RGEFCIA-----KFVDGEWYRARVEKVESPAKIHV 761
            G F I+      F D +W+  RVE+    A + V
Sbjct: 858 NGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQV 892


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,138,798
Number of Sequences: 37866
Number of extensions: 1559035
Number of successful extensions: 4314
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 4244
Number of HSP's gapped (non-prelim): 64
length of query: 910
length of database: 18,247,518
effective HSP length: 111
effective length of query: 799
effective length of database: 14,044,392
effective search space: 11221469208
effective search space used: 11221469208
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press