BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|77404397 staphylococcal nuclease domain containing 1 [Homo sapiens] (910 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|77404397 staphylococcal nuclease domain containing 1 [Homo sa... 1812 0.0 gi|38505161 tudor domain containing 1 [Homo sapiens] 58 5e-08 gi|94421471 ring finger protein 17 [Homo sapiens] 56 1e-07 gi|58197558 tudor domain containing 6 [Homo sapiens] 54 9e-07 gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 49 2e-05 gi|145312246 tudor and KH domain containing isoform b [Homo sapi... 49 2e-05 gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 49 2e-05 gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 49 2e-05 gi|169163653 PREDICTED: similar to tudor domain containing 1 [Ho... 48 4e-05 gi|169164192 PREDICTED: similar to tudor domain containing 1 [Ho... 48 4e-05 gi|169163210 PREDICTED: similar to tudor domain containing 1 [Ho... 48 4e-05 gi|112293287 tudor domain containing 7 [Homo sapiens] 46 2e-04 gi|40255178 tudor domain containing 5 [Homo sapiens] 44 5e-04 gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens] 41 0.006 gi|170784859 serine/threonine kinase 31 isoform b [Homo sapiens] 39 0.029 gi|14602443 serine/threonine kinase 31 isoform a [Homo sapiens] 39 0.029 gi|170784856 serine/threonine kinase 31 isoform b [Homo sapiens] 39 0.029 gi|166851804 tudor domain containing 9 [Homo sapiens] 36 0.14 gi|28416940 Shwachman-Bodian-Diamond syndrome protein [Homo sapi... 35 0.32 gi|189571674 cadherin-like 23 isoform 1 precursor [Homo sapiens] 33 1.2 gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] 32 2.7 gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens] 32 3.5 gi|9910266 kinesin family member 15 [Homo sapiens] 31 6.0 gi|148806891 hypothetical protein LOC54906 [Homo sapiens] 31 6.0 gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens] 30 7.8 gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 30 7.8 gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap... 30 7.8 gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap... 30 7.8 >gi|77404397 staphylococcal nuclease domain containing 1 [Homo sapiens] Length = 910 Score = 1812 bits (4694), Expect = 0.0 Identities = 910/910 (100%), Positives = 910/910 (100%) Query: 1 MASSAQSGGSSGGPAVPTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLA 60 MASSAQSGGSSGGPAVPTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLA Sbjct: 1 MASSAQSGGSSGGPAVPTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLA 60 Query: 61 RRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNG 120 RRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNG Sbjct: 61 RRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNG 120 Query: 121 ENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTI 180 ENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTI Sbjct: 121 ENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTI 180 Query: 181 ENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGSET 240 ENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGSET Sbjct: 181 ENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGSET 240 Query: 241 PEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWS 300 PEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWS Sbjct: 241 PEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWS 300 Query: 301 IAVYTRGAEKLRAAERFAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKL 360 IAVYTRGAEKLRAAERFAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKL Sbjct: 301 IAVYTRGAEKLRAAERFAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKL 360 Query: 361 NSGDYKTIHLSSIRPPRLEGENTQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVD 420 NSGDYKTIHLSSIRPPRLEGENTQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVD Sbjct: 361 NSGDYKTIHLSSIRPPRLEGENTQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVD 420 Query: 421 YIRPASPATETVPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELL 480 YIRPASPATETVPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELL Sbjct: 421 YIRPASPATETVPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELL 480 Query: 481 AAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRL 540 AAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRL Sbjct: 481 AAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRL 540 Query: 541 KLYLPKETCLITFLLAGIECPRGARNLPGLVQEGEPFSEEATLFTKELVLQREVEVEVES 600 KLYLPKETCLITFLLAGIECPRGARNLPGLVQEGEPFSEEATLFTKELVLQREVEVEVES Sbjct: 541 KLYLPKETCLITFLLAGIECPRGARNLPGLVQEGEPFSEEATLFTKELVLQREVEVEVES 600 Query: 601 MDKAGNFIGWLHIDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAH 660 MDKAGNFIGWLHIDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAH Sbjct: 601 MDKAGNFIGWLHIDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAH 660 Query: 661 YEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIAS 720 YEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIAS Sbjct: 661 YEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIAS 720 Query: 721 HPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTL 780 HPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTL Sbjct: 721 HPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTL 780 Query: 781 SPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHV 840 SPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHV Sbjct: 781 SPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHV 840 Query: 841 TLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRA 900 TLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRA Sbjct: 841 TLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRA 900 Query: 901 DDADEFGYSR 910 DDADEFGYSR Sbjct: 901 DDADEFGYSR 910 >gi|38505161 tudor domain containing 1 [Homo sapiens] Length = 1189 Score = 57.8 bits (138), Expect = 5e-08 Identities = 37/95 (38%), Positives = 51/95 (53%), Gaps = 6/95 (6%) Query: 687 VTEITDDLHFYVQ--DVETGTQLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKF-VDG 743 VTE FYVQ E + +L +++ A+ E Y P +GE CIAK+ VD Sbjct: 270 VTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVH--EKDYIPVKGEVCIAKYTVDQ 327 Query: 744 EWYRARVEKVE-SPAKIHVFYIDYGNREVLPSTRL 777 W RA ++ V+ K HV YIDYGN E++P R+ Sbjct: 328 TWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRI 362 Score = 56.2 bits (134), Expect = 1e-07 Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 4/117 (3%) Query: 687 VTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKFV-DGEW 745 V I F+ Q +++G +L +L ++ PP Y P G+ C A+F D +W Sbjct: 500 VAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFY-PAIGDICCAQFSEDDQW 558 Query: 746 YRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQ 802 YRA V S + V Y+DYGN E+L RL + P LP QA + A ++ Sbjct: 559 YRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLE--LPMQAIKCVLAGVK 613 Score = 44.7 bits (104), Expect = 4e-04 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 5/97 (5%) Query: 709 KLMENMRNDIASH--PPVEGSYAPRRGEFCIAKFV-DGEWYRARVEKVESPAKIHVFYID 765 K + ++ +A H + + G+ C A F DG WYRA V+++ + V ++D Sbjct: 740 KKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVD 799 Query: 766 YGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQ 802 YGN E + + L +S F LP Q A IQ Sbjct: 800 YGNIEEVTADELRMISSTFLN--LPFQGIRCQLADIQ 834 Score = 43.5 bits (101), Expect = 9e-04 Identities = 27/59 (45%), Positives = 31/59 (52%), Gaps = 6/59 (10%) Query: 720 SHPPVEGSYAPRRGEFCIAKFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRL 777 S PP Y PR G+ C AK+ D WYRA V S + V Y DYGN E LP R+ Sbjct: 985 SRPP----YRPRIGDACCAKYTSDDFWYRAVVLGT-SDTDVEVLYADYGNIETLPLCRV 1038 >gi|94421471 ring finger protein 17 [Homo sapiens] Length = 1623 Score = 56.2 bits (134), Expect = 1e-07 Identities = 73/317 (23%), Positives = 131/317 (41%), Gaps = 33/317 (10%) Query: 569 GLVQEGEPFSEEATLFTKELVLQR-----EVEVEVESMDKAGNFIGWLHIDGANLSVLLV 623 GL+++ +P ++ +L K++V Q E E +VE + N + + VL+V Sbjct: 564 GLLKDIQPLAQPCSL--KDIVPQNSNEGWEEEAKVEFLKMVNNKAVSMKVFREEDGVLIV 621 Query: 624 EHALSKVH-FTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKERSASY 682 + + +++ + L E AK K + + +H+E+ P + KE + Sbjct: 622 DLQKPPPNKISSDMPVSLRDALVFMELAKFKSQSLRSHFEKNTTLHYHPPILPKEMTDV- 680 Query: 683 KPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSY-APRRGEFCIAKFV 741 V V I FY+Q +E G + L++ + S P + + C+AKF Sbjct: 681 -SVTVCHINSPGDFYLQLIE-GLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKFE 738 Query: 742 DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFI 801 DG WYRA+V + ++ V Y+D+GN + + + F P +A + A+I Sbjct: 739 DGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLN--APEKAIKCKLAYI 796 Query: 802 QVPQ-------------DDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHVTLQFADSK 848 + + ++ A+ + V I LL S G P +T + + Sbjct: 797 EPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTTSINDQ 856 Query: 849 GDVGLGLVKEGLVMVEV 865 LVKEGL E+ Sbjct: 857 ------LVKEGLASYEI 867 Score = 43.9 bits (102), Expect = 7e-04 Identities = 67/333 (20%), Positives = 137/333 (41%), Gaps = 60/333 (18%) Query: 574 GEPFSEEATLFTKELVLQREVEVEVESMDKAGNFIGW------LHIDGANLSVLLVEHAL 627 G + +A ++L+ +R+V++ + + K W L+ DG +LS + + Sbjct: 1300 GNVWQPDAIEVLQQLLSKRQVDIHIMELPKNP----WEKLSIHLYFDGMSLSYFMAYYKY 1355 Query: 628 SKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQ-PVEEVMPVLEEKERSASYKP-- 684 T E K ++ K ++E+ +EE E P+L S+ P Sbjct: 1356 CTSEHTEEM---LKEKPRSDHDKKYEEEQWEIRFEELLSAETDTPLLPPYLSSSLPSPGE 1412 Query: 685 VFVTEIT-----DDLHFYVQDVETGTQ--------------------LEKLMENMRNDIA 719 ++ ++ ++++ + +ET Q L++ ++ + + Sbjct: 1413 LYAVQVKHVVSPNEVYICLDSIETSNQSNQHSDTDDSGVSGESESESLDEALQRVNKKVE 1472 Query: 720 SHPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVE--SPAKIHVFYIDYGNREVLPSTRL 777 + PP+ R C+A++ DG WYRA++ ++ +P I V ++DYG+ L RL Sbjct: 1473 ALPPLTDF---RTEMPCLAEYDDGLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLTLNRL 1529 Query: 778 GTLSPAFSTRVLPAQATEYAFAFIQVPQDDDART----------DAVDSVVRDIQNTQCL 827 + P+ R PA+A + A + P D T +A+ +++ +Q Q Sbjct: 1530 CQI-PSHLMR-YPARAIKVLLAGFKPPLRDLGETRIPYCPKWSMEALWAMIDCLQGKQ-- 1585 Query: 828 LNVEHLSAGCPHVTLQFADSKGDVGLGLVKEGL 860 L ++ + + D + V + LV+ GL Sbjct: 1586 LYAVSMAPAPEQIVTLYDDEQHPVHMPLVEMGL 1618 Score = 41.2 bits (95), Expect = 0.004 Identities = 37/124 (29%), Positives = 54/124 (43%), Gaps = 10/124 (8%) Query: 663 EQPVEEVMPVLEEKERSASYKPVFVTEIT--DDLHFYVQDVETGTQLEKLME----NMRN 716 EQ V E + E + YKP + + + V D T + KL E M N Sbjct: 1153 EQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVVPKLSEFELIKMTN 1212 Query: 717 DIASHPPVEGSYAP---RRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLP 773 +I S+ G P ++GE C + D WYR +V +V A + V Y+D+G E +P Sbjct: 1213 EIQSNLKCLGLLEPYFWKKGEACAVRGSDTLWYRGKVMEVVGGA-VRVQYLDHGFTEKIP 1271 Query: 774 STRL 777 L Sbjct: 1272 QCHL 1275 Score = 33.1 bits (74), Expect = 1.2 Identities = 30/129 (23%), Positives = 52/129 (40%), Gaps = 28/129 (21%) Query: 666 VEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQ---DVETGTQLEKLMENMRNDIASHP 722 +EE++ E +S + VFV+ + D HFY++ ++ LEK + N + Sbjct: 404 IEEII----EDNVESSAELVFVSHVIDPCHFYIRKYSQIKDAKVLEKKVNEFCNRSSHLD 459 Query: 723 PVEGSYAPRRGEFCIAKFVDGEWYRARVEK-------------------VESPAKIHVFY 763 P + R ++ +G W R + + V A I +F Sbjct: 460 PSDILELGAR--IFVSSIKNGMWCRGTITELIPIEGRNTRKPCSPTRLFVHEVALIQIFM 517 Query: 764 IDYGNREVL 772 +D+GN EVL Sbjct: 518 VDFGNSEVL 526 >gi|58197558 tudor domain containing 6 [Homo sapiens] Length = 2096 Score = 53.5 bits (127), Expect = 9e-07 Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 4/127 (3%) Query: 685 VFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKFV-DG 743 V+V+ I D FYVQ +E ++ L E + N + + P +RG+ A F D Sbjct: 1309 VYVSHINDLSDFYVQLIEDEAEISHLSERL-NSVKTRPEYYVGPPLQRGDMICAVFPEDN 1367 Query: 744 EWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQV 803 WYRA +++ + + V +IDYGN V+ + ++G L +LP + +V Sbjct: 1368 LWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLD--LVNAILPGLCIHCSLQGFEV 1425 Query: 804 PQDDDAR 810 P + +++ Sbjct: 1426 PDNKNSK 1432 Score = 50.8 bits (120), Expect = 6e-06 Identities = 41/135 (30%), Positives = 63/135 (46%), Gaps = 27/135 (20%) Query: 685 VFVTEITDDLHFYVQDVETG----------TQLEKLMENMRNDIASHPPVEGSYAPRRGE 734 V++T I D FY Q TQL K++ N++ + G Sbjct: 990 VYITHIDDPWTFYCQLARNANILEQLSCSITQLSKVLLNLKTSPLNP-----------GT 1038 Query: 735 FCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTL-SPAFSTRVLPAQA 793 C+AK+ DG WYR V + E P K VF++D+GN V+ S L + S A+ +LP QA Sbjct: 1039 LCLAKYTDGNWYRGIVIEKE-PKK--VFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQA 1095 Query: 794 TEYAFAFI--QVPQD 806 + + I +P++ Sbjct: 1096 VRCSLSDIPDHIPEE 1110 Score = 39.7 bits (91), Expect = 0.013 Identities = 54/244 (22%), Positives = 98/244 (40%), Gaps = 25/244 (10%) Query: 567 LPGLVQEGEPFSEEATLFTKELVLQREVEVEVESMDKAGN--FIGWLHIDGANLSVLLVE 624 L GL G +S K L+L + V ++E + ++ DG NL+ + Sbjct: 378 LYGLWDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYYVSLYGEDGINLNRV--- 434 Query: 625 HALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEV-----MPVLEE-KER 678 F + +L ++ +++ E + P EEV +P L + + Sbjct: 435 -------FGVQSCCLADRVLQSQATEEEEPE---TSQSQSPAEEVDEEISLPALRSIRLK 484 Query: 679 SASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYA-PRRGEFCI 737 ++ V + + F+++ + KLM M +S ++G P + C Sbjct: 485 MNAFYDAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCC 544 Query: 738 AKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYA 797 K+ + +YRA V K++ + + VF +D GN E + + L P F R LP A + Sbjct: 545 VKWKENGYYRAIVTKLDDKS-VDVFLVDRGNSENVDWYDVRMLLPQF--RQLPILAVKCT 601 Query: 798 FAFI 801 A I Sbjct: 602 LADI 605 Score = 36.6 bits (83), Expect = 0.11 Identities = 16/50 (32%), Positives = 32/50 (64%), Gaps = 1/50 (2%) Query: 736 CIAK-FVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAF 784 C+AK V+ +W RA + ++S ++V ++DYG+RE++ + ++S F Sbjct: 823 CLAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEF 872 Score = 35.0 bits (79), Expect = 0.32 Identities = 17/53 (32%), Positives = 29/53 (54%), Gaps = 1/53 (1%) Query: 733 GEFCIAKFVDGEWYRARVEKVESPAK-IHVFYIDYGNREVLPSTRLGTLSPAF 784 G C + +DG WYRA + + P + V ++DYG +E++ + L L P + Sbjct: 314 GSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEY 366 >gi|145312259 tudor and KH domain containing isoform a [Homo sapiens] Length = 561 Score = 48.9 bits (115), Expect = 2e-05 Identities = 64/265 (24%), Positives = 112/265 (42%), Gaps = 23/265 (8%) Query: 643 LLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKERSAS-----YKPVFVTEITDDLHFY 697 ++S E + ++ + + E Q + E MP+ E S Y V+V+ HF+ Sbjct: 264 VVSKEGSWEKPSDDSFQKSEAQAIPE-MPMFEIPSPDFSFHADEYLEVYVSASEHPNHFW 322 Query: 698 VQDVETGT-QLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKF-VDGEWYRARVEKVES 755 +Q V + + QL+KL+ M + P + G+ A +G WYRARV Sbjct: 323 IQIVGSRSLQLDKLVNEMTQHYENSVPED--LTVHVGDIVAAPLPTNGSWYRARVLGTLE 380 Query: 756 PAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVD 815 + ++++D+G+ P L L F + LP QA E + A I P D +A+D Sbjct: 381 NGNLDLYFVDFGDNGDCPLKDLRALRSDFLS--LPFQAIECSLARI-APSGDQWEEEALD 437 Query: 816 SVVRDIQNTQCLLNVEHLS-------AGCPHVTLQFADS--KGDVGLGLVKEGLVMVEVR 866 R V +S + P + L + K D+GL LV +G +E+ Sbjct: 438 EFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYA-IELP 496 Query: 867 KEKQFQKVITEYLNAQESAKSARLN 891 ++ + + + + L + A L+ Sbjct: 497 EDIEENRAVPDMLKDMATETDASLS 521 >gi|145312246 tudor and KH domain containing isoform b [Homo sapiens] Length = 516 Score = 48.9 bits (115), Expect = 2e-05 Identities = 64/265 (24%), Positives = 112/265 (42%), Gaps = 23/265 (8%) Query: 643 LLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKERSAS-----YKPVFVTEITDDLHFY 697 ++S E + ++ + + E Q + E MP+ E S Y V+V+ HF+ Sbjct: 219 VVSKEGSWEKPSDDSFQKSEAQAIPE-MPMFEIPSPDFSFHADEYLEVYVSASEHPNHFW 277 Query: 698 VQDVETGT-QLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKF-VDGEWYRARVEKVES 755 +Q V + + QL+KL+ M + P + G+ A +G WYRARV Sbjct: 278 IQIVGSRSLQLDKLVNEMTQHYENSVPED--LTVHVGDIVAAPLPTNGSWYRARVLGTLE 335 Query: 756 PAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVD 815 + ++++D+G+ P L L F + LP QA E + A I P D +A+D Sbjct: 336 NGNLDLYFVDFGDNGDCPLKDLRALRSDFLS--LPFQAIECSLARI-APSGDQWEEEALD 392 Query: 816 SVVRDIQNTQCLLNVEHLS-------AGCPHVTLQFADS--KGDVGLGLVKEGLVMVEVR 866 R V +S + P + L + K D+GL LV +G +E+ Sbjct: 393 EFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYA-IELP 451 Query: 867 KEKQFQKVITEYLNAQESAKSARLN 891 ++ + + + + L + A L+ Sbjct: 452 EDIEENRAVPDMLKDMATETDASLS 476 >gi|145312270 tudor and KH domain containing isoform a [Homo sapiens] Length = 561 Score = 48.9 bits (115), Expect = 2e-05 Identities = 64/265 (24%), Positives = 112/265 (42%), Gaps = 23/265 (8%) Query: 643 LLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKERSAS-----YKPVFVTEITDDLHFY 697 ++S E + ++ + + E Q + E MP+ E S Y V+V+ HF+ Sbjct: 264 VVSKEGSWEKPSDDSFQKSEAQAIPE-MPMFEIPSPDFSFHADEYLEVYVSASEHPNHFW 322 Query: 698 VQDVETGT-QLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKF-VDGEWYRARVEKVES 755 +Q V + + QL+KL+ M + P + G+ A +G WYRARV Sbjct: 323 IQIVGSRSLQLDKLVNEMTQHYENSVPED--LTVHVGDIVAAPLPTNGSWYRARVLGTLE 380 Query: 756 PAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVD 815 + ++++D+G+ P L L F + LP QA E + A I P D +A+D Sbjct: 381 NGNLDLYFVDFGDNGDCPLKDLRALRSDFLS--LPFQAIECSLARI-APSGDQWEEEALD 437 Query: 816 SVVRDIQNTQCLLNVEHLS-------AGCPHVTLQFADS--KGDVGLGLVKEGLVMVEVR 866 R V +S + P + L + K D+GL LV +G +E+ Sbjct: 438 EFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYA-IELP 496 Query: 867 KEKQFQKVITEYLNAQESAKSARLN 891 ++ + + + + L + A L+ Sbjct: 497 EDIEENRAVPDMLKDMATETDASLS 521 >gi|145312256 tudor and KH domain containing isoform a [Homo sapiens] Length = 561 Score = 48.9 bits (115), Expect = 2e-05 Identities = 64/265 (24%), Positives = 112/265 (42%), Gaps = 23/265 (8%) Query: 643 LLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKERSAS-----YKPVFVTEITDDLHFY 697 ++S E + ++ + + E Q + E MP+ E S Y V+V+ HF+ Sbjct: 264 VVSKEGSWEKPSDDSFQKSEAQAIPE-MPMFEIPSPDFSFHADEYLEVYVSASEHPNHFW 322 Query: 698 VQDVETGT-QLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKF-VDGEWYRARVEKVES 755 +Q V + + QL+KL+ M + P + G+ A +G WYRARV Sbjct: 323 IQIVGSRSLQLDKLVNEMTQHYENSVPED--LTVHVGDIVAAPLPTNGSWYRARVLGTLE 380 Query: 756 PAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVD 815 + ++++D+G+ P L L F + LP QA E + A I P D +A+D Sbjct: 381 NGNLDLYFVDFGDNGDCPLKDLRALRSDFLS--LPFQAIECSLARI-APSGDQWEEEALD 437 Query: 816 SVVRDIQNTQCLLNVEHLS-------AGCPHVTLQFADS--KGDVGLGLVKEGLVMVEVR 866 R V +S + P + L + K D+GL LV +G +E+ Sbjct: 438 EFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYA-IELP 496 Query: 867 KEKQFQKVITEYLNAQESAKSARLN 891 ++ + + + + L + A L+ Sbjct: 497 EDIEENRAVPDMLKDMATETDASLS 521 >gi|169163653 PREDICTED: similar to tudor domain containing 1 [Homo sapiens] Length = 2080 Score = 48.1 bits (113), Expect = 4e-05 Identities = 52/208 (25%), Positives = 98/208 (47%), Gaps = 12/208 (5%) Query: 686 FVTEITDDLHFYVQDVETGTQLEKLMENMRN--DIASHPPVEGSYAPRRGEFCIAKFV-D 742 F+ + + +F+V+ + + +++M+N+ D+ + + P G FC A++ D Sbjct: 633 FIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCENDEMI-LRKPEPGLFCCARYSKD 691 Query: 743 GEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQ 802 +YRA + ++ KI+V+++DYGN + +P + L P F LPA A + A I Sbjct: 692 RRFYRAVITEING-YKINVYFLDYGNTDSIPFFDVKILLPEFCE--LPALAMCCSLAHI- 747 Query: 803 VPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHVTLQFADSKG--DVGLGLVKEGL 860 P +D A+D + + N LL V V +Q ++ DV +++ G Sbjct: 748 FPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSVEASENIDVISLMLQAGY 807 Query: 861 VMVEVRKEKQFQKVITEY--LNAQESAK 886 + + F K ++EY LN++ K Sbjct: 808 AEYFQVELEYFPKSVSEYSMLNSESKNK 835 Score = 47.4 bits (111), Expect = 6e-05 Identities = 27/119 (22%), Positives = 56/119 (47%) Query: 666 VEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVE 725 ++ V+ L+ S + V V+ FY Q ++ +LE L +M + Sbjct: 372 IQHVLDKLQPSLSVGSTESVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQET 431 Query: 726 GSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAF 784 G C+A+ +G+W+R ++++ P ++ ++++DYG+ E +PS + L F Sbjct: 432 SPTCDNFGLLCVARRRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDF 490 Score = 41.6 bits (96), Expect = 0.003 Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 7/107 (6%) Query: 681 SYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDI--ASHPPVEGSYAPRRGEFCIA 738 S + V+++ I FY Q LE + + + + P Y + CI+ Sbjct: 1111 SEEEVYISHIYSPQKFYCQLGRNNKDLEMIETKITESVNLQNFP----KYDSNKMRVCIS 1166 Query: 739 KFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAF 784 K+V DG YRA +S ++ V+++D+GN++++ L +S F Sbjct: 1167 KYVEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQF 1213 Score = 39.7 bits (91), Expect = 0.013 Identities = 29/129 (22%), Positives = 62/129 (48%), Gaps = 6/129 (4%) Query: 663 EQPVEEVMPVLEEKERSASYKPV----FVTEITDDLHFYVQDVETGTQLEKLMENMRNDI 718 + P + + P +++ + Y +V+ I++ +F++Q E + + +L + + N Sbjct: 1419 QNPYDLIRPQIKDLPQPQIYLNAKVKGYVSNISNPANFHIQLAENESVIIRLADAL-NAT 1477 Query: 719 ASHPPVEGSYAPRRGEFCIAKFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRL 777 A S P G+ +A++ D YRA ++K+ V +IDYGN ++ ++++ Sbjct: 1478 ARRLRERKSVKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKI 1537 Query: 778 GTLSPAFST 786 L F T Sbjct: 1538 YELQREFLT 1546 Score = 31.6 bits (70), Expect = 3.5 Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 3/63 (4%) Query: 732 RGEFCIAKFVDG-EWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLP 790 +G C+AK + +W+R++VE+ K+ VF +D G E++P LS R +P Sbjct: 1723 KGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSN--EIRNIP 1780 Query: 791 AQA 793 QA Sbjct: 1781 RQA 1783 >gi|169164192 PREDICTED: similar to tudor domain containing 1 [Homo sapiens] Length = 2080 Score = 48.1 bits (113), Expect = 4e-05 Identities = 52/208 (25%), Positives = 98/208 (47%), Gaps = 12/208 (5%) Query: 686 FVTEITDDLHFYVQDVETGTQLEKLMENMRN--DIASHPPVEGSYAPRRGEFCIAKFV-D 742 F+ + + +F+V+ + + +++M+N+ D+ + + P G FC A++ D Sbjct: 633 FIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCENDEMI-LRKPEPGLFCCARYSKD 691 Query: 743 GEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQ 802 +YRA + ++ KI+V+++DYGN + +P + L P F LPA A + A I Sbjct: 692 RRFYRAVITEING-YKINVYFLDYGNTDSIPFFDVKILLPEFCE--LPALAMCCSLAHI- 747 Query: 803 VPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHVTLQFADSKG--DVGLGLVKEGL 860 P +D A+D + + N LL V V +Q ++ DV +++ G Sbjct: 748 FPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSVEASENIDVISLMLQAGY 807 Query: 861 VMVEVRKEKQFQKVITEY--LNAQESAK 886 + + F K ++EY LN++ K Sbjct: 808 AEYFQVELEYFPKSVSEYSMLNSESKNK 835 Score = 47.4 bits (111), Expect = 6e-05 Identities = 27/119 (22%), Positives = 56/119 (47%) Query: 666 VEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVE 725 ++ V+ L+ S + V V+ FY Q ++ +LE L +M + Sbjct: 372 IQHVLDKLQPSLSVGSTESVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQET 431 Query: 726 GSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAF 784 G C+A+ +G+W+R ++++ P ++ ++++DYG+ E +PS + L F Sbjct: 432 SPTCDNFGLLCVARRRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDF 490 Score = 41.6 bits (96), Expect = 0.003 Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 7/107 (6%) Query: 681 SYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDI--ASHPPVEGSYAPRRGEFCIA 738 S + V+++ I FY Q LE + + + + P Y + CI+ Sbjct: 1111 SEEEVYISHIYSPQKFYCQLGRNNKDLEMIETKITESVNLQNFP----KYDSNKMRVCIS 1166 Query: 739 KFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAF 784 K+V DG YRA +S ++ V+++D+GN++++ L +S F Sbjct: 1167 KYVEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQF 1213 Score = 39.7 bits (91), Expect = 0.013 Identities = 29/129 (22%), Positives = 62/129 (48%), Gaps = 6/129 (4%) Query: 663 EQPVEEVMPVLEEKERSASYKPV----FVTEITDDLHFYVQDVETGTQLEKLMENMRNDI 718 + P + + P +++ + Y +V+ I++ +F++Q E + + +L + + N Sbjct: 1419 QNPYDLIRPQIKDLPQPQIYLNAKVKGYVSNISNPANFHIQLAENESVIIRLADAL-NAT 1477 Query: 719 ASHPPVEGSYAPRRGEFCIAKFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRL 777 A S P G+ +A++ D YRA ++K+ V +IDYGN ++ ++++ Sbjct: 1478 ARRLRERKSVKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKI 1537 Query: 778 GTLSPAFST 786 L F T Sbjct: 1538 YELQREFLT 1546 Score = 31.6 bits (70), Expect = 3.5 Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 3/63 (4%) Query: 732 RGEFCIAKFVDG-EWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLP 790 +G C+AK + +W+R++VE+ K+ VF +D G E++P LS R +P Sbjct: 1723 KGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSN--EIRNIP 1780 Query: 791 AQA 793 QA Sbjct: 1781 RQA 1783 >gi|169163210 PREDICTED: similar to tudor domain containing 1 [Homo sapiens] Length = 2080 Score = 48.1 bits (113), Expect = 4e-05 Identities = 52/208 (25%), Positives = 98/208 (47%), Gaps = 12/208 (5%) Query: 686 FVTEITDDLHFYVQDVETGTQLEKLMENMRN--DIASHPPVEGSYAPRRGEFCIAKFV-D 742 F+ + + +F+V+ + + +++M+N+ D+ + + P G FC A++ D Sbjct: 633 FIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCENDEMI-LRKPEPGLFCCARYSKD 691 Query: 743 GEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQ 802 +YRA + ++ KI+V+++DYGN + +P + L P F LPA A + A I Sbjct: 692 RRFYRAVITEING-YKINVYFLDYGNTDSIPFFDVKILLPEFCE--LPALAMCCSLAHI- 747 Query: 803 VPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHVTLQFADSKG--DVGLGLVKEGL 860 P +D A+D + + N LL V V +Q ++ DV +++ G Sbjct: 748 FPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSVEASENIDVISLMLQAGY 807 Query: 861 VMVEVRKEKQFQKVITEY--LNAQESAK 886 + + F K ++EY LN++ K Sbjct: 808 AEYFQVELEYFPKSVSEYSMLNSESKNK 835 Score = 47.4 bits (111), Expect = 6e-05 Identities = 27/119 (22%), Positives = 56/119 (47%) Query: 666 VEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVE 725 ++ V+ L+ S + V V+ FY Q ++ +LE L +M + Sbjct: 372 IQHVLDKLQPSLSVGSTESVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQET 431 Query: 726 GSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAF 784 G C+A+ +G+W+R ++++ P ++ ++++DYG+ E +PS + L F Sbjct: 432 SPTCDNFGLLCVARRRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDF 490 Score = 41.6 bits (96), Expect = 0.003 Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 7/107 (6%) Query: 681 SYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDI--ASHPPVEGSYAPRRGEFCIA 738 S + V+++ I FY Q LE + + + + P Y + CI+ Sbjct: 1111 SEEEVYISHIYSPQKFYCQLGRNNKDLEMIETKITESVNLQNFP----KYDSNKMRVCIS 1166 Query: 739 KFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAF 784 K+V DG YRA +S ++ V+++D+GN++++ L +S F Sbjct: 1167 KYVEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQF 1213 Score = 39.7 bits (91), Expect = 0.013 Identities = 29/129 (22%), Positives = 62/129 (48%), Gaps = 6/129 (4%) Query: 663 EQPVEEVMPVLEEKERSASYKPV----FVTEITDDLHFYVQDVETGTQLEKLMENMRNDI 718 + P + + P +++ + Y +V+ I++ +F++Q E + + +L + + N Sbjct: 1419 QNPYDLIRPQIKDLPQPQIYLNAKVKGYVSNISNPANFHIQLAENESVIIRLADAL-NAT 1477 Query: 719 ASHPPVEGSYAPRRGEFCIAKFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRL 777 A S P G+ +A++ D YRA ++K+ V +IDYGN ++ ++++ Sbjct: 1478 ARRLRERKSVKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKI 1537 Query: 778 GTLSPAFST 786 L F T Sbjct: 1538 YELQREFLT 1546 Score = 31.6 bits (70), Expect = 3.5 Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 3/63 (4%) Query: 732 RGEFCIAKFVDG-EWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLP 790 +G C+AK + +W+R++VE+ K+ VF +D G E++P LS R +P Sbjct: 1723 KGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSN--EIRNIP 1780 Query: 791 AQA 793 QA Sbjct: 1781 RQA 1783 >gi|112293287 tudor domain containing 7 [Homo sapiens] Length = 1098 Score = 45.8 bits (107), Expect = 2e-04 Identities = 40/149 (26%), Positives = 67/149 (44%), Gaps = 4/149 (2%) Query: 669 VMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSY 728 V P++ E S S V ++ + + YV + Q E + + M+ + +P + Sbjct: 454 VPPLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQ-ELMEDEMKEYYSKNPKITPVQ 512 Query: 729 APRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRV 788 A G+ + W RA+V E KI V Y+DYG E + ++ L+P F + Sbjct: 513 AVNVGQLLAVNAEEDAWLRAQVISTEEN-KIKVCYVDYGFSENVEKSKAYKLNPKFCS-- 569 Query: 789 LPAQATEYAFAFIQVPQDDDARTDAVDSV 817 L QAT+ A ++V DD V+S+ Sbjct: 570 LSFQATKCKLAGLEVLSDDPDLVKVVESL 598 Score = 36.6 bits (83), Expect = 0.11 Identities = 35/152 (23%), Positives = 65/152 (42%), Gaps = 6/152 (3%) Query: 654 KEKVWAHYEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMEN 713 K+ + H EE+ P + + + V+V +F +Q + +LE LME Sbjct: 886 KKSMVDHTSAFSTEELPPPVH-LSKPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEE 944 Query: 714 MRNDIASHPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLP 773 M I + E + + A V+ +W+R ++ + + + V+ +DYG E++ Sbjct: 945 M---ILYYSVSEERHIAVEKDQVYAAKVENKWHRVLLKGILTNGLVSVYELDYGKHELVN 1001 Query: 774 STRLGTLSPAFSTRVLPAQATEYAFAFIQVPQ 805 ++ L F R LP QA A ++ Q Sbjct: 1002 IRKVQPLVDMF--RKLPFQAVTAQLAGVKCNQ 1031 >gi|40255178 tudor domain containing 5 [Homo sapiens] Length = 981 Score = 44.3 bits (103), Expect = 5e-04 Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 9/125 (7%) Query: 685 VFVTEITDDLHFYVQ--DVETGTQLEKLMENMR----NDIASHPPVEGSYAPRRGEFCIA 738 VFV I FY++ ++ LE +M MR N + S V + G C Sbjct: 475 VFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCV 534 Query: 739 KFVDGEW-YRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYA 797 + + +W YR + +V ++ VFY D+GN ++ + L L ++ LPAQA + Sbjct: 535 RISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTK--LPAQAIPCS 592 Query: 798 FAFIQ 802 A+++ Sbjct: 593 LAWVR 597 >gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens] Length = 903 Score = 40.8 bits (94), Expect = 0.006 Identities = 37/130 (28%), Positives = 55/130 (42%), Gaps = 7/130 (5%) Query: 736 CIAKFVDGEWYRAR-VEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQAT 794 C A DG W+RA+ V E ++ + Y+DYG + + L + F T LP Q Sbjct: 765 CAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVT--LPFQGA 822 Query: 795 EYAFAFIQVPQDDDARTDAVDSVVRDIQ-NTQCLLNVEHLS-AGCPHVTL--QFADSKGD 850 E + DDD + D+ + ++ NT L V S G P + L D Sbjct: 823 EVLLDSVMPLSDDDQFSPEADAAMSEMTGNTALLAQVTSYSPTGLPLIQLWSVVGDEVVL 882 Query: 851 VGLGLVKEGL 860 + LV+ GL Sbjct: 883 INRSLVERGL 892 >gi|170784859 serine/threonine kinase 31 isoform b [Homo sapiens] Length = 996 Score = 38.5 bits (88), Expect = 0.029 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 7/103 (6%) Query: 673 LEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRR 732 ++E + V + I D + F+ Q + + K+ ++ V G+ P + Sbjct: 1 MDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDPNK 60 Query: 733 ---GEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVL 772 G F D WYR +V K+ S K V YIDYGN E+L Sbjct: 61 IYGGLFS----EDQCWYRCKVLKIISVEKCLVRYIDYGNTEIL 99 >gi|14602443 serine/threonine kinase 31 isoform a [Homo sapiens] Length = 1019 Score = 38.5 bits (88), Expect = 0.029 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 7/103 (6%) Query: 673 LEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRR 732 ++E + V + I D + F+ Q + + K+ ++ V G+ P + Sbjct: 24 MDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDPNK 83 Query: 733 ---GEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVL 772 G F D WYR +V K+ S K V YIDYGN E+L Sbjct: 84 IYGGLFS----EDQCWYRCKVLKIISVEKCLVRYIDYGNTEIL 122 >gi|170784856 serine/threonine kinase 31 isoform b [Homo sapiens] Length = 996 Score = 38.5 bits (88), Expect = 0.029 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 7/103 (6%) Query: 673 LEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRR 732 ++E + V + I D + F+ Q + + K+ ++ V G+ P + Sbjct: 1 MDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDPNK 60 Query: 733 ---GEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVL 772 G F D WYR +V K+ S K V YIDYGN E+L Sbjct: 61 IYGGLFS----EDQCWYRCKVLKIISVEKCLVRYIDYGNTEIL 99 >gi|166851804 tudor domain containing 9 [Homo sapiens] Length = 1382 Score = 36.2 bits (82), Expect = 0.14 Identities = 36/154 (23%), Positives = 69/154 (44%), Gaps = 12/154 (7%) Query: 650 AKQKKEKVWAHYEEQPVEEVMPVLEEKERSASYKPVF----VTEITDDLHFYVQDVETGT 705 +K + +V +++Q V+ + +RS + + VTE+ + HF+ ++ Sbjct: 863 SKLRNTRVNVDFQKQTVDPMQVSFNTSDRSQTVTDLLLTIDVTEVVEVGHFWGYRIDENN 922 Query: 706 QLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKFVDGE---WYRARVEKVESPAKIHVF 762 ++++ + +I V P C+A F D + ++RA+V V S VF Sbjct: 923 S--EILKKLTAEINQLTLVPLPTHPHPDLVCLAPFADFDKQRYFRAQVLYV-SGNSAEVF 979 Query: 763 YIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEY 796 ++DYGN+ + L + F LP QA E+ Sbjct: 980 FVDYGNKSHVDLHLLMEIPCQFLE--LPFQALEF 1011 >gi|28416940 Shwachman-Bodian-Diamond syndrome protein [Homo sapiens] Length = 250 Score = 35.0 bits (79), Expect = 0.32 Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 5/84 (5%) Query: 619 SVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKER 678 +V+L+E A+ +H++ + + K A E KQ KEK+ + ++PV E K+ Sbjct: 129 TVILIERAMKDIHYSVKTNKSTKQ--QALEVIKQLKEKMKIERAHMRLRFILPVNEGKKL 186 Query: 679 SASYKPVFVTEITDDLHFYVQDVE 702 KP+ ++D Y Q +E Sbjct: 187 KEKLKPLIKVIESED---YGQQLE 207 >gi|189571674 cadherin-like 23 isoform 1 precursor [Homo sapiens] Length = 3354 Score = 33.1 bits (74), Expect = 1.2 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 2/67 (2%) Query: 447 GINIAEALVSKGLATVIRYRQDDDQRS--SHYDELLAAEARAIKNGKGLHSKKEVPIHRV 504 GI++ LAT + ++DQ+ + L AAEA A + S K P+H++ Sbjct: 3281 GIHVVHGSTGTLLATDLNSLPEEDQKGLGRSLETLTAAEATAFERNARTESAKSTPLHKL 3340 Query: 505 ADISGDT 511 D+ +T Sbjct: 3341 RDVIMET 3347 >gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] Length = 1243 Score = 32.0 bits (71), Expect = 2.7 Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 18/65 (27%) Query: 37 GQPRGGPPPERQINLS-----NIRAGNLARRA-------------AATQPDAKDTPDEPW 78 GQPR GPPP R S R+ L+RR+ A+ PD D PD Sbjct: 32 GQPRLGPPPRRARRFSGKAEPRPRSSRLSRRSSVDLGLLSSWSLPASPAPDPPDPPDSAG 91 Query: 79 AFPAR 83 PAR Sbjct: 92 PGPAR 96 >gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens] Length = 2156 Score = 31.6 bits (70), Expect = 3.5 Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 8/100 (8%) Query: 595 EVEVESMDKAGNFIGWLHIDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKK 654 E +V S++ A ++ LH + LS + +K H AE+S K L+ E +K+ Sbjct: 1006 ETQVGSLNDA--YLVPLH-EHCTLSQSAINDHNTKSHIAAEKSGPEKKLVYQEINLARKR 1062 Query: 655 EKVWAHYEEQPVEE-----VMPVLEEKERSASYKPVFVTE 689 + V A + P+EE ++PVL + AS + T+ Sbjct: 1063 QSVEAAIQVDPIEEETPKDLLPVLMLHQLQASVPGIHKTQ 1102 >gi|9910266 kinesin family member 15 [Homo sapiens] Length = 1388 Score = 30.8 bits (68), Expect = 6.0 Identities = 31/117 (26%), Positives = 48/117 (41%), Gaps = 24/117 (20%) Query: 625 HALSKVHFTAERSSYYKSLLSA--EEAAK-------------QKKEKVWA-----HYEEQ 664 HA +++ E S + LL + EE K QKKE+V +++ + Sbjct: 1067 HATEQLNMLTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMR 1126 Query: 665 PVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETG----TQLEKLMENMRND 717 +E VM E +S P F T + L Q++E G T LE L+ + D Sbjct: 1127 QLEHVMDSAAEDPQSPKTPPHFQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNED 1183 >gi|148806891 hypothetical protein LOC54906 [Homo sapiens] Length = 2430 Score = 30.8 bits (68), Expect = 6.0 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 1/55 (1%) Query: 506 DISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRLKL-YLPKETCLITFLLAGIE 559 D+SG+ + +LPF R+ E ++ V + +KL + KE C TFL +E Sbjct: 2137 DVSGEATAQEMYLPFPGRSASYEDIIIDVCTNLHVKLRSVVKEACKSTFLFYLVE 2191 >gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens] Length = 1621 Score = 30.4 bits (67), Expect = 7.8 Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 2/84 (2%) Query: 465 YRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRA 524 Y Q + S+ +D A GL +VP VA G + + +P +RA Sbjct: 1448 YSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKG--KPSSDTVPKPKRA 1505 Query: 525 GRSEAVVEYVFSGSRLKLYLPKET 548 + + VVE V S S + +PK+T Sbjct: 1506 PKQKKVVEAVNSDSDSEFGIPKKT 1529 >gi|90669307 cyclin B3 isoform 3 [Homo sapiens] Length = 1395 Score = 30.4 bits (67), Expect = 7.8 Identities = 33/106 (31%), Positives = 50/106 (47%), Gaps = 18/106 (16%) Query: 576 PFSEEATLFTKELVLQREVEVEVE-------SMDKAGNFIGWLHIDGANLSVL--LVEHA 626 P +EEA+LF K LVL+ E +E E S+ K N H + + L L L E + Sbjct: 146 PNTEEASLFRKPLVLKEEPTIEDETLINKSLSLKKCSN-----HEEVSLLEKLQPLQEES 200 Query: 627 LSKVHFTAERSSYYKSLLSAEEAAKQK----KEKVWAHYEEQPVEE 668 S F E ++ K+ + E A +K K+K+ A +Q +E Sbjct: 201 DSDDAFVIEPMTFKKTHKTEEAAITKKTLSLKKKMCASQRKQSCQE 246 >gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sapiens] Length = 1235 Score = 30.4 bits (67), Expect = 7.8 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 8/95 (8%) Query: 675 EKERSASYKPVFVTEITDDLHFYVQDV-ETGTQLEKL--MENMRNDIASHPPVEGSYAPR 731 + E S + P F E++ D+ F+ + +G LE L + +R ++ S V S+ Sbjct: 725 DTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVG 784 Query: 732 RGEFCIA-----KFVDGEWYRARVEKVESPAKIHV 761 G F I+ F D +W+ RVE+ A + V Sbjct: 785 NGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQV 819 >gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sapiens] Length = 1308 Score = 30.4 bits (67), Expect = 7.8 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 8/95 (8%) Query: 675 EKERSASYKPVFVTEITDDLHFYVQDV-ETGTQLEKL--MENMRNDIASHPPVEGSYAPR 731 + E S + P F E++ D+ F+ + +G LE L + +R ++ S V S+ Sbjct: 798 DTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVG 857 Query: 732 RGEFCIA-----KFVDGEWYRARVEKVESPAKIHV 761 G F I+ F D +W+ RVE+ A + V Sbjct: 858 NGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQV 892 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.134 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 34,138,798 Number of Sequences: 37866 Number of extensions: 1559035 Number of successful extensions: 4314 Number of sequences better than 10.0: 28 Number of HSP's better than 10.0 without gapping: 11 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 4244 Number of HSP's gapped (non-prelim): 64 length of query: 910 length of database: 18,247,518 effective HSP length: 111 effective length of query: 799 effective length of database: 14,044,392 effective search space: 11221469208 effective search space used: 11221469208 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.