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Search of human proteins with 7706659
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706659 paired related homeobox 2 [Homo sapiens]
(253 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706659 paired related homeobox 2 [Homo sapiens] 504 e-143
gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi... 260 7e-70
gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens] 215 3e-56
gi|24497589 aristaless related homeobox [Homo sapiens] 109 2e-24
gi|46249382 paired-like homeobox 2a [Homo sapiens] 109 3e-24
gi|12707580 paired-like homeobox 2b [Homo sapiens] 108 3e-24
gi|126116581 retina and anterior neural fold homeobox [Homo sapi... 108 4e-24
gi|189083681 paired box gene 6 isoform a [Homo sapiens] 107 1e-23
gi|4580424 paired box gene 6 isoform b [Homo sapiens] 107 1e-23
gi|4505615 paired box gene 6 isoform a [Homo sapiens] 107 1e-23
gi|113204604 aristaless-like homeobox 3 [Homo sapiens] 105 3e-23
gi|14249388 retina and anterior neural fold homeobox 2 [Homo sap... 105 5e-23
gi|55743092 aristaless-like homeobox 4 [Homo sapiens] 102 2e-22
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens] 101 7e-22
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 101 7e-22
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 101 7e-22
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 101 7e-22
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 101 7e-22
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 101 7e-22
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 101 7e-22
gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 101 7e-22
gi|152963644 paired-like homeodomain transcription factor 1 [Hom... 100 9e-22
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens] 99 3e-21
gi|14149760 orthopedia homeobox [Homo sapiens] 99 3e-21
gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom... 99 4e-21
gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Hom... 99 4e-21
gi|57232759 intestine-specific homeobox [Homo sapiens] 97 1e-20
gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens] 96 4e-20
gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens] 96 4e-20
gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens] 95 5e-20
>gi|7706659 paired related homeobox 2 [Homo sapiens]
Length = 253
Score = 504 bits (1297), Expect = e-143
Identities = 253/253 (100%), Positives = 253/253 (100%)
Query: 1 MDSAAAAFALDKPALGPGPPPPPPALGPGDCAQARKNFSVSHLLDLEEVAAAGRLAARPG 60
MDSAAAAFALDKPALGPGPPPPPPALGPGDCAQARKNFSVSHLLDLEEVAAAGRLAARPG
Sbjct: 1 MDSAAAAFALDKPALGPGPPPPPPALGPGDCAQARKNFSVSHLLDLEEVAAAGRLAARPG 60
Query: 61 ARAEAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALE 120
ARAEAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALE
Sbjct: 61 ARAEAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALE 120
Query: 121 RVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQ 180
RVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQ
Sbjct: 121 RVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQ 180
Query: 181 EAAIEQPVAPRPTALSPDYLSWTASSPYSTVPPYSPGSSGPATPGVNMANSIASLRLKAK 240
EAAIEQPVAPRPTALSPDYLSWTASSPYSTVPPYSPGSSGPATPGVNMANSIASLRLKAK
Sbjct: 181 EAAIEQPVAPRPTALSPDYLSWTASSPYSTVPPYSPGSSGPATPGVNMANSIASLRLKAK 240
Query: 241 EFSLHHSQVPTVN 253
EFSLHHSQVPTVN
Sbjct: 241 EFSLHHSQVPTVN 253
>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
sapiens]
Length = 245
Score = 260 bits (665), Expect = 7e-70
Identities = 154/244 (63%), Positives = 179/244 (73%), Gaps = 25/244 (10%)
Query: 24 PALG-----PG--DCAQARKNFSVSHLLDLEEVAAAGRLAARPGARAEAREGAAR----E 72
PALG PG D QA+KNFSVSHLLDLEE AG + A A+A+ G A E
Sbjct: 13 PALGGRLDSPGNLDTLQAKKNFSVSHLLDLEE---AGDMVA---AQADENVGEAGRSLLE 66
Query: 73 PSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAF 132
G +SGS+ QD + S K+K+KQRRNRTTFNSSQLQALERVFERTHYPDAF
Sbjct: 67 SPGLTSGSDTPQQDND----QLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAF 122
Query: 133 VREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQE-AAIEQPVAPR 191
VRE+LARRVNL+EARVQVWFQNRRAKFRRNERAMLA+++ASLLKSYS + A+EQP+ PR
Sbjct: 123 VREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQPIVPR 182
Query: 192 PTALSPDYLSWTASSPYSTVPPYSP--GSSGPATPGVNMANSIASLRLKAKEFSLHHSQV 249
P DYLSW +SPYS + YS ++ PA G+NMANSIA+LRLKAKE+SL +QV
Sbjct: 183 PAPRPTDYLSWGTASPYSAMATYSATCANNSPA-QGINMANSIANLRLKAKEYSLQRNQV 241
Query: 250 PTVN 253
PTVN
Sbjct: 242 PTVN 245
>gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]
Length = 217
Score = 215 bits (547), Expect = 3e-56
Identities = 126/197 (63%), Positives = 144/197 (73%), Gaps = 22/197 (11%)
Query: 24 PALG-----PG--DCAQARKNFSVSHLLDLEEVAAAGRLAARPGARAEAREGAAR----E 72
PALG PG D QA+KNFSVSHLLDLEE AG + A A+A+ G A E
Sbjct: 13 PALGGRLDSPGNLDTLQAKKNFSVSHLLDLEE---AGDMVA---AQADENVGEAGRSLLE 66
Query: 73 PSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAF 132
G +SGS+ QD + S K+K+KQRRNRTTFNSSQLQALERVFERTHYPDAF
Sbjct: 67 SPGLTSGSDTPQQDND----QLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAF 122
Query: 133 VREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQE-AAIEQPVAPR 191
VRE+LARRVNL+EARVQVWFQNRRAKFRRNERAMLA+++ASLLKSYS + A+EQP+ PR
Sbjct: 123 VREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQPIVPR 182
Query: 192 PTALSPDYLSWTASSPY 208
P DYLSW +SPY
Sbjct: 183 PAPRPTDYLSWGTASPY 199
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 109 bits (273), Expect = 2e-24
Identities = 77/174 (44%), Positives = 92/174 (52%), Gaps = 26/174 (14%)
Query: 49 VAAAGRLAARPGARAEAREGAAREPSGGS--SGSEAAPQDGE---CPSPGRGSA-AKRKK 102
VAA G +AA A A A EG P +A +DGE C S G S K+
Sbjct: 268 VAATGAVAAAAAA-AVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKR 326
Query: 103 KQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRN 162
KQRR RTTF S QL+ LER F++THYPD F REELA R++L+EARVQVWFQNRRAK+R+
Sbjct: 327 KQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKR 386
Query: 163 ERAMLASRSASLLKSYSQEAAIEQPVAPRPTALSPDYLSWTASSPYSTVPPYSP 216
E+A A P P P LS + SPY P+ P
Sbjct: 387 EKA---------------GAQTHPPGLPFPGPLSATH----PLSPYLDASPFPP 421
Score = 30.4 bits (67), Expect = 1.5
Identities = 15/28 (53%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Query: 3 SAAAAFALDKPALGPGPPPPPPALGPGD 30
+AAAA A P G PPPPPP PG+
Sbjct: 111 AAAAATATAGPR-GEAPPPPPPTARPGE 137
>gi|46249382 paired-like homeobox 2a [Homo sapiens]
Length = 284
Score = 109 bits (272), Expect = 3e-24
Identities = 62/127 (48%), Positives = 78/127 (61%), Gaps = 6/127 (4%)
Query: 96 SAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNR 155
S K+KQRR RTTF S+QL+ LERVF THYPD + REELA +++L+EARVQVWFQNR
Sbjct: 82 SGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNR 141
Query: 156 RAKFRRNERAMLASRSASLLKSYSQEA-AIEQPVAPRPTALSPDYLSWTASSPYSTVPPY 214
RAKFR+ ERA A +A + EA + + + SP T S S PP
Sbjct: 142 RAKFRKQERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSP-----TPDSTASLPPPP 196
Query: 215 SPGSSGP 221
+PG + P
Sbjct: 197 APGLASP 203
>gi|12707580 paired-like homeobox 2b [Homo sapiens]
Length = 314
Score = 108 bits (271), Expect = 3e-24
Identities = 61/139 (43%), Positives = 83/139 (59%), Gaps = 14/139 (10%)
Query: 101 KKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFR 160
K+KQRR RTTF S+QL+ LERVF THYPD + REELA +++L+EARVQVWFQNRRAKFR
Sbjct: 95 KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 154
Query: 161 RNERAMLASRSASLLKSYSQEA-AIEQPVAPRPTALSPDYLSWTASSPYST--------- 210
+ ERA A+ +A+ S +++ + + + PD +P T
Sbjct: 155 KQERAAAAAAAAAKNGSSGKKSDSSRDDESKEAKSTDPDSTGGPGPNPNPTPSCGANGGG 214
Query: 211 ----VPPYSPGSSGPATPG 225
P +PG++GP PG
Sbjct: 215 GGGPSPAGAPGAAGPGGPG 233
>gi|126116581 retina and anterior neural fold homeobox [Homo
sapiens]
Length = 346
Score = 108 bits (270), Expect = 4e-24
Identities = 72/174 (41%), Positives = 88/174 (50%), Gaps = 29/174 (16%)
Query: 59 PGARAEAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAA-----KRKKKQRRNRTTFNS 113
P A A A E A P EA P G P G A + KKK RRNRTTF +
Sbjct: 86 PPAPAPAPEYEAPRPYCPKEPGEARPSPGLPVGPATGEAKLSEEEQPKKKHRRNRTTFTT 145
Query: 114 SQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSAS 173
QL LER FE++HYPD + REELA +VNL E RVQVWFQNRRAK+RR E+ ++S
Sbjct: 146 YQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKLEVSSMKLQ 205
Query: 174 LLKSYSQEAAIEQPVAPRPTALSPDYLSWTASSPYSTVPPY--SPGSSGPATPG 225
+ P+ LS++ S P +T+ P PGS G G
Sbjct: 206 -----------DSPL-----------LSFSRSPPSATLSPLGAGPGSGGGPAGG 237
>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 107 bits (267), Expect = 1e-23
Identities = 71/218 (32%), Positives = 106/218 (48%), Gaps = 30/218 (13%)
Query: 53 GRLAARPG------ARAEAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRR 106
G RPG + + ++ GG + + +GE S + K+K +R
Sbjct: 154 GSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGE-DSDEAQMRLQLKRKLQR 212
Query: 107 NRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAM 166
NRT+F Q++ALE+ FERTHYPD F RE LA +++L EAR+QVWF NRRAK+RR E+
Sbjct: 213 NRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLR 272
Query: 167 LASRSASLLKSY-----SQEAAIEQPVAPRPTALSPDYLSWT--------ASSPYSTVPP 213
R AS S+ S ++ QP+ P+PT + S + ++ YS +PP
Sbjct: 273 NQRRQASNTPSHIPISSSFSTSVYQPI-PQPTTPVSSFTSGSMLGRTDTALTNTYSALPP 331
Query: 214 YSPGSSGPATPGVNMANSIASLRLKAKEFSLHHSQVPT 251
P MAN++ + S + +PT
Sbjct: 332 ---------MPSFTMANNLPMQPPVPSQTSSYSCMLPT 360
>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
Length = 436
Score = 107 bits (267), Expect = 1e-23
Identities = 71/218 (32%), Positives = 106/218 (48%), Gaps = 30/218 (13%)
Query: 53 GRLAARPG------ARAEAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRR 106
G RPG + + ++ GG + + +GE S + K+K +R
Sbjct: 168 GSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGE-DSDEAQMRLQLKRKLQR 226
Query: 107 NRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAM 166
NRT+F Q++ALE+ FERTHYPD F RE LA +++L EAR+QVWF NRRAK+RR E+
Sbjct: 227 NRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLR 286
Query: 167 LASRSASLLKSY-----SQEAAIEQPVAPRPTALSPDYLSWT--------ASSPYSTVPP 213
R AS S+ S ++ QP+ P+PT + S + ++ YS +PP
Sbjct: 287 NQRRQASNTPSHIPISSSFSTSVYQPI-PQPTTPVSSFTSGSMLGRTDTALTNTYSALPP 345
Query: 214 YSPGSSGPATPGVNMANSIASLRLKAKEFSLHHSQVPT 251
P MAN++ + S + +PT
Sbjct: 346 ---------MPSFTMANNLPMQPPVPSQTSSYSCMLPT 374
>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 107 bits (267), Expect = 1e-23
Identities = 71/218 (32%), Positives = 106/218 (48%), Gaps = 30/218 (13%)
Query: 53 GRLAARPG------ARAEAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRR 106
G RPG + + ++ GG + + +GE S + K+K +R
Sbjct: 154 GSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGE-DSDEAQMRLQLKRKLQR 212
Query: 107 NRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAM 166
NRT+F Q++ALE+ FERTHYPD F RE LA +++L EAR+QVWF NRRAK+RR E+
Sbjct: 213 NRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLR 272
Query: 167 LASRSASLLKSY-----SQEAAIEQPVAPRPTALSPDYLSWT--------ASSPYSTVPP 213
R AS S+ S ++ QP+ P+PT + S + ++ YS +PP
Sbjct: 273 NQRRQASNTPSHIPISSSFSTSVYQPI-PQPTTPVSSFTSGSMLGRTDTALTNTYSALPP 331
Query: 214 YSPGSSGPATPGVNMANSIASLRLKAKEFSLHHSQVPT 251
P MAN++ + S + +PT
Sbjct: 332 ---------MPSFTMANNLPMQPPVPSQTSSYSCMLPT 360
>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
Length = 343
Score = 105 bits (263), Expect = 3e-23
Identities = 95/295 (32%), Positives = 129/295 (43%), Gaps = 78/295 (26%)
Query: 13 PALGP-----GPPPPPPA-----LGPGDCAQARKNFSVSHLLD--LEEVAAAGRLAARPG 60
PA GP P PPA LGPG H + E + A+ P
Sbjct: 52 PACGPLEPYLPEPAKPPAKYLQDLGPGPALNG------GHFYEGPAEAEEKTSKAASFPQ 105
Query: 61 ARAEAREGAAREPSGGSSGSEAAPQDGECP-------SPGRGSA---AKRKKKQRRNRTT 110
+ R G P G S + +P G C SPG + AK K K+RRNRTT
Sbjct: 106 LPLDCRGG----PRDGPSNLQGSP--GPCLASLHLPLSPGLPDSMELAKNKSKKRRNRTT 159
Query: 111 FNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNER------ 164
F++ QL+ LE+VF++THYPD + RE+LA R +L+EARVQVWFQNRRAK+R+ ER
Sbjct: 160 FSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQE 219
Query: 165 ---AMLASRSASLLKSYSQEAAIEQPVAPRPTA--------LSPDYLSWTASSPYS---- 209
A+ S+L ++ + P + +SP+ + SPYS
Sbjct: 220 GRNPFTAAYDISVLPRTDSHPQLQNSLWASPGSGSPGGPCLVSPEGIPSPCMSPYSHPHG 279
Query: 210 ----------------------TVPPYSPGSS-GPATPGVNMANSIASLRLKAKE 241
PP G S P++ G + S+ SLR+K KE
Sbjct: 280 SVAGFMGVPAPSAAHPGIYSIHGFPPTLGGHSFEPSSDGDYKSPSLVSLRVKPKE 334
>gi|14249388 retina and anterior neural fold homeobox 2 [Homo
sapiens]
Length = 184
Score = 105 bits (261), Expect = 5e-23
Identities = 78/176 (44%), Positives = 89/176 (50%), Gaps = 32/176 (18%)
Query: 91 SPGRGSAAKR----------KKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARR 140
SPG G A + KKK RRNRTTF + QL LER FE +HYPD + REELA +
Sbjct: 4 SPGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAK 63
Query: 141 VNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQEAAIEQPVAP--RPTALSPD 198
V+L E RVQVWFQNRRAK+RR ER L S S ++ EA P P RP A+S
Sbjct: 64 VHLPEVRVQVWFQNRRAKWRRQER--LESGSGAVAAPRLPEA----PALPFARPPAMSLP 117
Query: 199 YLSWTASSPYSTVP---------PYSPGSSGPATPGVNMANSI----ASLRLKAKE 241
W P VP P S GP A+ ASLRL AKE
Sbjct: 118 LEPWLGPGP-PAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASLRLLAKE 172
>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
Length = 411
Score = 102 bits (255), Expect = 2e-22
Identities = 78/216 (36%), Positives = 103/216 (47%), Gaps = 57/216 (26%)
Query: 84 PQD---GECPSP-GRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELAR 139
PQD + PSP + + K K+RRNRTTF S QL+ LE+VF++THYPD + RE+LA
Sbjct: 190 PQDRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAM 249
Query: 140 RVNLSEARVQVWFQNRRAKFRRNER---------AMLASRSASLLKSYSQEAAIEQP--- 187
R +L+EARVQVWFQNRRAK+R+ ER + LL A I+ P
Sbjct: 250 RTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWL 309
Query: 188 -----VAPRPTALSPDYLSWTASSPYSTVPPYSPGSS----------------------- 219
+P P + P SP++ PP S SS
Sbjct: 310 GNNGAASPVPACVVPCDPVPACMSPHAH-PPGSGASSVTDFLSVSGAGSHVGQTHMGSLF 368
Query: 220 --GPATPGVN----------MANSIASLRLKAKEFS 243
+PG+N +SIA+LR+KAKE S
Sbjct: 369 GAASLSPGLNGYELNGEPDRKTSSIAALRMKAKEHS 404
>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
Length = 331
Score = 101 bits (251), Expect = 7e-22
Identities = 61/126 (48%), Positives = 77/126 (61%), Gaps = 9/126 (7%)
Query: 49 VAAAGRLAARPGARAEARE---GAA---REPSGGSSGSEAAPQ--DGECPSPGRGSAAKR 100
V G G R+ RE GAA REP G +E +P+ D + + G +
Sbjct: 78 VGGGGAGGGAGGGRSPVRELDMGAAERSREP-GSPRLTEVSPELKDRKEDAKGMEDEGQT 136
Query: 101 KKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFR 160
K KQRR+RT F QL LER+F+ THYPDAF+REEL++R+ LSEARVQVWFQNRRAK R
Sbjct: 137 KIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCR 196
Query: 161 RNERAM 166
+ E +
Sbjct: 197 KQENQL 202
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 101 bits (251), Expect = 7e-22
Identities = 70/184 (38%), Positives = 91/184 (49%), Gaps = 13/184 (7%)
Query: 64 EAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVF 123
E+ + A G S +APQ E K+KQRR+RTTF + QL+ LER F
Sbjct: 178 ESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAF 237
Query: 124 ERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQEAA 183
ERTHYPD + REELA+R L+EARVQVWF NRRA++R+ A L+ A
Sbjct: 238 ERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTA 297
Query: 184 IEQPVAP----RPTALSPDYLSWTASSPYSTV---PPYSPG----SSGPATPGVNMANSI 232
+ P P T+ P + S P STV P P S+ P+ P + A +
Sbjct: 298 M--PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCL 355
Query: 233 ASLR 236
S R
Sbjct: 356 PSTR 359
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 101 bits (251), Expect = 7e-22
Identities = 70/184 (38%), Positives = 91/184 (49%), Gaps = 13/184 (7%)
Query: 64 EAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVF 123
E+ + A G S +APQ E K+KQRR+RTTF + QL+ LER F
Sbjct: 179 ESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAF 238
Query: 124 ERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQEAA 183
ERTHYPD + REELA+R L+EARVQVWF NRRA++R+ A L+ A
Sbjct: 239 ERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTA 298
Query: 184 IEQPVAP----RPTALSPDYLSWTASSPYSTV---PPYSPG----SSGPATPGVNMANSI 232
+ P P T+ P + S P STV P P S+ P+ P + A +
Sbjct: 299 M--PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCL 356
Query: 233 ASLR 236
S R
Sbjct: 357 PSTR 360
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 101 bits (251), Expect = 7e-22
Identities = 70/184 (38%), Positives = 91/184 (49%), Gaps = 13/184 (7%)
Query: 64 EAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVF 123
E+ + A G S +APQ E K+KQRR+RTTF + QL+ LER F
Sbjct: 179 ESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAF 238
Query: 124 ERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQEAA 183
ERTHYPD + REELA+R L+EARVQVWF NRRA++R+ A L+ A
Sbjct: 239 ERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTA 298
Query: 184 IEQPVAP----RPTALSPDYLSWTASSPYSTV---PPYSPG----SSGPATPGVNMANSI 232
+ P P T+ P + S P STV P P S+ P+ P + A +
Sbjct: 299 M--PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCL 356
Query: 233 ASLR 236
S R
Sbjct: 357 PSTR 360
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 101 bits (251), Expect = 7e-22
Identities = 70/184 (38%), Positives = 91/184 (49%), Gaps = 13/184 (7%)
Query: 64 EAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVF 123
E+ + A G S +APQ E K+KQRR+RTTF + QL+ LER F
Sbjct: 179 ESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAF 238
Query: 124 ERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQEAA 183
ERTHYPD + REELA+R L+EARVQVWF NRRA++R+ A L+ A
Sbjct: 239 ERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTA 298
Query: 184 IEQPVAP----RPTALSPDYLSWTASSPYSTV---PPYSPG----SSGPATPGVNMANSI 232
+ P P T+ P + S P STV P P S+ P+ P + A +
Sbjct: 299 M--PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCL 356
Query: 233 ASLR 236
S R
Sbjct: 357 PSTR 360
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 101 bits (251), Expect = 7e-22
Identities = 70/184 (38%), Positives = 91/184 (49%), Gaps = 13/184 (7%)
Query: 64 EAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVF 123
E+ + A G S +APQ E K+KQRR+RTTF + QL+ LER F
Sbjct: 179 ESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAF 238
Query: 124 ERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQEAA 183
ERTHYPD + REELA+R L+EARVQVWF NRRA++R+ A L+ A
Sbjct: 239 ERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTA 298
Query: 184 IEQPVAP----RPTALSPDYLSWTASSPYSTV---PPYSPG----SSGPATPGVNMANSI 232
+ P P T+ P + S P STV P P S+ P+ P + A +
Sbjct: 299 M--PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCL 356
Query: 233 ASLR 236
S R
Sbjct: 357 PSTR 360
>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
Length = 479
Score = 101 bits (251), Expect = 7e-22
Identities = 70/184 (38%), Positives = 91/184 (49%), Gaps = 13/184 (7%)
Query: 64 EAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVF 123
E+ + A G S +APQ E K+KQRR+RTTF + QL+ LER F
Sbjct: 179 ESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAF 238
Query: 124 ERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQEAA 183
ERTHYPD + REELA+R L+EARVQVWF NRRA++R+ A L+ A
Sbjct: 239 ERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTA 298
Query: 184 IEQPVAP----RPTALSPDYLSWTASSPYSTV---PPYSPG----SSGPATPGVNMANSI 232
+ P P T+ P + S P STV P P S+ P+ P + A +
Sbjct: 299 M--PTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCL 356
Query: 233 ASLR 236
S R
Sbjct: 357 PSTR 360
>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
Length = 268
Score = 101 bits (251), Expect = 7e-22
Identities = 46/64 (71%), Positives = 55/64 (85%)
Query: 101 KKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFR 160
++KQRRNRTTF QL+ALE VF +THYPD F REELA ++NL+EARVQVWFQNRRAK+R
Sbjct: 35 RRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWR 94
Query: 161 RNER 164
+ ER
Sbjct: 95 KTER 98
>gi|152963644 paired-like homeodomain transcription factor 1 [Homo
sapiens]
Length = 314
Score = 100 bits (250), Expect = 9e-22
Identities = 68/173 (39%), Positives = 84/173 (48%), Gaps = 33/173 (19%)
Query: 1 MDSAAAAFALDKPALGPGPPPPPPA-LGPGDCAQARKNFSVSHLLDLEEVAAAGRLAARP 59
MD+ +L++ G PPPPPP +GP HL ARP
Sbjct: 1 MDAFKGGMSLERLPEGLRPPPPPPHDMGPA-----------FHL-------------ARP 36
Query: 60 GARAEAREGAARE------PSGGSSGSEAAPQDGECPSPGRGSA--AKRKKKQRRNRTTF 111
E E +A E P G P+D G G A +KKKQRR RT F
Sbjct: 37 ADPREPLENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHF 96
Query: 112 NSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNER 164
S QLQ LE F+R YPD +REE+A NL+E RV+VWF+NRRAK+R+ ER
Sbjct: 97 TSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRER 149
>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
Length = 325
Score = 99.4 bits (246), Expect = 3e-21
Identities = 69/220 (31%), Positives = 103/220 (46%), Gaps = 18/220 (8%)
Query: 24 PALGPGDCAQARKNFSVSHLLDLEEVAAAGRLAARPGARAEAREGAAREPSGGSSGSEAA 83
P PGD A + LL E++ G + P + A + + ++P
Sbjct: 38 PGGHPGDLAPNSDPVEGATLLPGEDITTVG---STPASLAVSAKDPDKQPG--------- 85
Query: 84 PQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNL 143
PQ G P+P + + ++KQ+R+RT F +QL LER F +THYPD F+REELA R+ L
Sbjct: 86 PQGG--PNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGL 143
Query: 144 SEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQEAAIEQPVAPRPTALSPDYLSWT 203
+E+RVQVWFQNRRAK+++ ++ R+ L A A+ S+
Sbjct: 144 TESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLCSFH 203
Query: 204 ASSPYSTVPPYSPGSSGPATPGVN----MANSIASLRLKA 239
A+ S P P + MA S++ L A
Sbjct: 204 ANDTRWAAAAMPGVSQLPLPPALGRQQAMAQSLSQCSLAA 243
>gi|14149760 orthopedia homeobox [Homo sapiens]
Length = 325
Score = 99.4 bits (246), Expect = 3e-21
Identities = 69/220 (31%), Positives = 103/220 (46%), Gaps = 18/220 (8%)
Query: 24 PALGPGDCAQARKNFSVSHLLDLEEVAAAGRLAARPGARAEAREGAAREPSGGSSGSEAA 83
P PGD A + LL E++ G + P + A + + ++P
Sbjct: 38 PGGHPGDLAPNSDPVEGATLLPGEDITTVG---STPASLAVSAKDPDKQPG--------- 85
Query: 84 PQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNL 143
PQ G P+P + + ++KQ+R+RT F +QL LER F +THYPD F+REELA R+ L
Sbjct: 86 PQGG--PNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGL 143
Query: 144 SEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQEAAIEQPVAPRPTALSPDYLSWT 203
+E+RVQVWFQNRRAK+++ ++ R+ L A A+ S+
Sbjct: 144 TESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLCSFH 203
Query: 204 ASSPYSTVPPYSPGSSGPATPGVN----MANSIASLRLKA 239
A+ S P P + MA S++ L A
Sbjct: 204 ANDTRWAAAAMPGVSQLPLPPALGRQQAMAQSLSQCSLAA 243
>gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo
sapiens]
Length = 382
Score = 99.0 bits (245), Expect = 4e-21
Identities = 58/133 (43%), Positives = 78/133 (58%), Gaps = 12/133 (9%)
Query: 102 KKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRR 161
+KQRR+RT F + QL+ALE+ F++THYPD +RE LA NL EARVQVWF+NRRAKFR+
Sbjct: 69 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 128
Query: 162 NERAMLASRSASLLKSYSQEAAIEQPVAPRPTALSPDYLSWTASSPYSTVPPYSPGSSGP 221
+R++ + L K E + + A PT PD T PP PGS P
Sbjct: 129 KQRSL---QKEQLQKQKEAEGSHGEGKAEAPT---PDTQLDTEQ------PPRLPGSDPP 176
Query: 222 ATPGVNMANSIAS 234
A ++++ AS
Sbjct: 177 AELHLSLSEQSAS 189
>gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Homo
sapiens]
Length = 377
Score = 99.0 bits (245), Expect = 4e-21
Identities = 58/133 (43%), Positives = 78/133 (58%), Gaps = 12/133 (9%)
Query: 102 KKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRR 161
+KQRR+RT F + QL+ALE+ F++THYPD +RE LA NL EARVQVWF+NRRAKFR+
Sbjct: 64 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 123
Query: 162 NERAMLASRSASLLKSYSQEAAIEQPVAPRPTALSPDYLSWTASSPYSTVPPYSPGSSGP 221
+R++ + L K E + + A PT PD T PP PGS P
Sbjct: 124 KQRSL---QKEQLQKQKEAEGSHGEGKAEAPT---PDTQLDTEQ------PPRLPGSDPP 171
Query: 222 ATPGVNMANSIAS 234
A ++++ AS
Sbjct: 172 AELHLSLSEQSAS 184
>gi|57232759 intestine-specific homeobox [Homo sapiens]
Length = 245
Score = 97.4 bits (241), Expect = 1e-20
Identities = 61/187 (32%), Positives = 91/187 (48%), Gaps = 25/187 (13%)
Query: 31 CAQARKNFSVSHLLDLEEVAAAGRLAARPGARAEAR--EGAAREPSGGSSGSEAAPQDGE 88
C +A K S+S ++ + RP R++ EG E G EAA
Sbjct: 20 CCEAPKKLSLSFSIEA--------ILKRPARRSDMDRPEGPGEEGPG-----EAAASGSG 66
Query: 89 CPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARV 148
P + + +K +RR RTTF + QL LE++F THYPD +R +LA R+NL EARV
Sbjct: 67 LEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARV 126
Query: 149 QVWFQNRRAKFRRNERAMLASRSASLLKSYSQEAAIEQPVAPRPTALSPDYLSWTASSPY 208
Q+WFQN+RAK+R+ E+ + + + + PT L +WT+++
Sbjct: 127 QIWFQNQRAKWRKQEK----------IGNLGAPQQLSEASVALPTNLDVAGPTWTSTALR 176
Query: 209 STVPPYS 215
PP S
Sbjct: 177 RLAPPTS 183
>gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens]
Length = 225
Score = 95.5 bits (236), Expect = 4e-20
Identities = 45/66 (68%), Positives = 53/66 (80%)
Query: 101 KKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFR 160
K KQRR+RT F QL LER+F+ THYPDAF+REEL++R+ LSEARVQVWFQNRRAK R
Sbjct: 114 KLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCR 173
Query: 161 RNERAM 166
+ E M
Sbjct: 174 KQENQM 179
>gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens]
Length = 292
Score = 95.5 bits (236), Expect = 4e-20
Identities = 45/66 (68%), Positives = 53/66 (80%)
Query: 101 KKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFR 160
K KQRR+RT F QL LER+F+ THYPDAF+REEL++R+ LSEARVQVWFQNRRAK R
Sbjct: 114 KLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCR 173
Query: 161 RNERAM 166
+ E M
Sbjct: 174 KQENQM 179
>gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]
Length = 326
Score = 95.1 bits (235), Expect = 5e-20
Identities = 43/62 (69%), Positives = 54/62 (87%)
Query: 103 KQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRN 162
K+RR+RTTF S QL+ LE+VF++THYPD +VRE+LA R L+EARVQVWFQNRRAK+R+
Sbjct: 131 KKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKR 190
Query: 163 ER 164
ER
Sbjct: 191 ER 192
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.126 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,208,317
Number of Sequences: 37866
Number of extensions: 666250
Number of successful extensions: 9906
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 384
Number of HSP's successfully gapped in prelim test: 380
Number of HSP's that attempted gapping in prelim test: 7870
Number of HSP's gapped (non-prelim): 2104
length of query: 253
length of database: 18,247,518
effective HSP length: 100
effective length of query: 153
effective length of database: 14,460,918
effective search space: 2212520454
effective search space used: 2212520454
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.