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Search of human proteins with 7706113
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706113 protocadherin 12 precursor [Homo sapiens]
(1184 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706113 protocadherin 12 precursor [Homo sapiens] 2341 0.0
gi|14589929 protocadherin 18 precursor [Homo sapiens] 593 e-169
gi|157426847 protocadherin 19 isoform a [Homo sapiens] 485 e-137
gi|157426845 protocadherin 19 isoform b [Homo sapiens] 485 e-137
gi|94538350 protocadherin 17 precursor [Homo sapiens] 473 e-133
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 466 e-131
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens] 466 e-131
gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso... 440 e-123
gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precurs... 440 e-123
gi|14270508 protocadherin gamma subfamily B, 7 isoform 2 precurs... 419 e-117
gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precurs... 419 e-117
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs... 416 e-116
gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur... 416 e-116
gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precurs... 416 e-116
gi|14196459 protocadherin gamma subfamily A, 1 isoform 2 precurs... 416 e-116
gi|14270499 protocadherin gamma subfamily B, 4 isoform 2 precurs... 414 e-115
gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precurs... 414 e-115
gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precurs... 414 e-115
gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precurs... 414 e-115
gi|11056030 protocadherin gamma subfamily A, 2 isoform 1 precurs... 414 e-115
gi|14196462 protocadherin gamma subfamily A, 2 isoform 2 precurs... 414 e-115
gi|11128035 protocadherin gamma subfamily B, 2 isoform 1 precurs... 412 e-114
gi|14270493 protocadherin gamma subfamily B, 2 isoform 2 precurs... 412 e-114
gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precurs... 411 e-114
gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precurs... 411 e-114
gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precurs... 409 e-114
gi|7662056 protocadherin gamma subfamily A, 8 isoform 2 precurso... 409 e-114
gi|14196471 protocadherin gamma subfamily A, 5 isoform 2 precurs... 409 e-114
gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precurs... 409 e-114
gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precurs... 407 e-113
>gi|7706113 protocadherin 12 precursor [Homo sapiens]
Length = 1184
Score = 2341 bits (6066), Expect = 0.0
Identities = 1184/1184 (100%), Positives = 1184/1184 (100%)
Query: 1 MMQLLQLLLGLLGPGGYLFLLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRR 60
MMQLLQLLLGLLGPGGYLFLLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRR
Sbjct: 1 MMQLLQLLLGLLGPGGYLFLLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRR 60
Query: 61 QAGAAFQVLQLPQALPIQVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIH 120
QAGAAFQVLQLPQALPIQVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIH
Sbjct: 61 QAGAAFQVLQLPQALPIQVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIH 120
Query: 121 VEIQVLDINDHQPRFPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHF 180
VEIQVLDINDHQPRFPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHF
Sbjct: 121 VEIQVLDINDHQPRFPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHF 180
Query: 181 ALDVIVGPDETKHAELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDN 240
ALDVIVGPDETKHAELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDN
Sbjct: 181 ALDVIVGPDETKHAELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDN 240
Query: 241 SPAFAESSLALEIQEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAK 300
SPAFAESSLALEIQEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAK
Sbjct: 241 SPAFAESSLALEIQEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAK 300
Query: 301 TGQVILRRPLDYEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQP 360
TGQVILRRPLDYEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQP
Sbjct: 301 TGQVILRRPLDYEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQP 360
Query: 361 SLVSEALPKDSFIALVMADDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDR 420
SLVSEALPKDSFIALVMADDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDR
Sbjct: 361 SLVSEALPKDSFIALVMADDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDR 420
Query: 421 EQWPKYTLTLLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLI 480
EQWPKYTLTLLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLI
Sbjct: 421 EQWPKYTLTLLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLI 480
Query: 481 TIKAHDADLGINGKVSYRIQDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDS 540
TIKAHDADLGINGKVSYRIQDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDS
Sbjct: 481 TIKAHDADLGINGKVSYRIQDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDS 540
Query: 541 GQPMLASSVSVWVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGP 600
GQPMLASSVSVWVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGP
Sbjct: 541 GQPMLASSVSVWVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGP 600
Query: 601 AGTDTPPLATHSSRPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNV 660
AGTDTPPLATHSSRPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNV
Sbjct: 601 AGTDTPPLATHSSRPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNV 660
Query: 661 TNASSLIGSEWELEIVVEDQGSPPLQTRALLRVMFVTSVDHLRDSARKPGALSMSMLTVI 720
TNASSLIGSEWELEIVVEDQGSPPLQTRALLRVMFVTSVDHLRDSARKPGALSMSMLTVI
Sbjct: 661 TNASSLIGSEWELEIVVEDQGSPPLQTRALLRVMFVTSVDHLRDSARKPGALSMSMLTVI 720
Query: 721 CLAVLLGIFGLILALFMSICRTEKKDNRAYNCREAESTYRQQPKRPQKHIQKADIHLVPV 780
CLAVLLGIFGLILALFMSICRTEKKDNRAYNCREAESTYRQQPKRPQKHIQKADIHLVPV
Sbjct: 721 CLAVLLGIFGLILALFMSICRTEKKDNRAYNCREAESTYRQQPKRPQKHIQKADIHLVPV 780
Query: 781 LRGQAGEPCEVGQSHKDVDKEAMMEAGWDPCLQAPFHLTPTLYRTLRNQGNQGAPAESRE 840
LRGQAGEPCEVGQSHKDVDKEAMMEAGWDPCLQAPFHLTPTLYRTLRNQGNQGAPAESRE
Sbjct: 781 LRGQAGEPCEVGQSHKDVDKEAMMEAGWDPCLQAPFHLTPTLYRTLRNQGNQGAPAESRE 840
Query: 841 VLQDTVNLLFNHPRQRNASRENLNLPEPQPATGQPRSRPLKVAGSPTGRLAGDQGSEEAP 900
VLQDTVNLLFNHPRQRNASRENLNLPEPQPATGQPRSRPLKVAGSPTGRLAGDQGSEEAP
Sbjct: 841 VLQDTVNLLFNHPRQRNASRENLNLPEPQPATGQPRSRPLKVAGSPTGRLAGDQGSEEAP 900
Query: 901 QRPPASSATLRRQRHLNGKVSPEKESGPRQILRSLVRLSVAAFAERNPVEELTVDSPPVQ 960
QRPPASSATLRRQRHLNGKVSPEKESGPRQILRSLVRLSVAAFAERNPVEELTVDSPPVQ
Sbjct: 901 QRPPASSATLRRQRHLNGKVSPEKESGPRQILRSLVRLSVAAFAERNPVEELTVDSPPVQ 960
Query: 961 QISQLLSLLHQGQFQPKPNHRGNKYLAKPGGSRSAIPDTDGPSARAGGQTDPEQEEGPLD 1020
QISQLLSLLHQGQFQPKPNHRGNKYLAKPGGSRSAIPDTDGPSARAGGQTDPEQEEGPLD
Sbjct: 961 QISQLLSLLHQGQFQPKPNHRGNKYLAKPGGSRSAIPDTDGPSARAGGQTDPEQEEGPLD 1020
Query: 1021 PEEDLSVKQLLEEELSSLLDPSTGLALDRLSAPDPAWMARLSLPLTTNYRDNVISPDAAA 1080
PEEDLSVKQLLEEELSSLLDPSTGLALDRLSAPDPAWMARLSLPLTTNYRDNVISPDAAA
Sbjct: 1021 PEEDLSVKQLLEEELSSLLDPSTGLALDRLSAPDPAWMARLSLPLTTNYRDNVISPDAAA 1080
Query: 1081 TEEPRTFQTFGKAEAPELSPTGTRLASTFVSEMSSLLEMLLEQRSSMPVEAASEALRRLS 1140
TEEPRTFQTFGKAEAPELSPTGTRLASTFVSEMSSLLEMLLEQRSSMPVEAASEALRRLS
Sbjct: 1081 TEEPRTFQTFGKAEAPELSPTGTRLASTFVSEMSSLLEMLLEQRSSMPVEAASEALRRLS 1140
Query: 1141 VCGRTLSLDLATSAASGMKVQGDPGGKTGTEGKSRGSSSSSRCL 1184
VCGRTLSLDLATSAASGMKVQGDPGGKTGTEGKSRGSSSSSRCL
Sbjct: 1141 VCGRTLSLDLATSAASGMKVQGDPGGKTGTEGKSRGSSSSSRCL 1184
>gi|14589929 protocadherin 18 precursor [Homo sapiens]
Length = 1135
Score = 593 bits (1529), Expect = e-169
Identities = 323/783 (41%), Positives = 486/783 (62%), Gaps = 48/783 (6%)
Query: 18 LFLLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERR--RQAGAAFQVLQLPQAL 75
L ++ +V +KY++ EE G+VI +LS+++ + + F+ +Q +
Sbjct: 16 LLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSP 75
Query: 76 PIQVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDV--LATGDLALIHVEIQVLDINDHQP 133
+ V+ + G +S G +DREQLC++ C + FDV L T L L H+E++VLDIND+ P
Sbjct: 76 LLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSP 135
Query: 134 RFPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKH 193
+F + +EISESA++ TRIPLD A DPD G N+LHTY+LS ++ F ++V D K+
Sbjct: 136 QFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKY 195
Query: 194 AELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEI 253
AELIVV+ELDRE+ S ++L LTA D G P +SG+S++K+++ DSNDNSPAF + S +++
Sbjct: 196 AELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQL 255
Query: 254 QEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYE 313
E++ GTLL+ L ATDPD+G NG++ + S H+ P++++TF ID++ G + L + +DYE
Sbjct: 256 LENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYE 315
Query: 314 KNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWAS----QPSLVSEALPK 369
+YE+DVQA+DLGPN IPAHCK++IKV+DVNDN P I++ S + S + E P
Sbjct: 316 ITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPI 375
Query: 370 DSFIALVMADDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLT 429
D+F+ALV D DSG NG + C L GHF+L++T N Y++LTNATLDRE+ +Y+LT
Sbjct: 376 DTFVALVRVQDKDSGLNGEIVCKLHGH-GHFKLQKTYENNYLILTNATLDREKRSEYSLT 434
Query: 430 LLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADL 489
++A+D+G LS K ++QI+DINDN P F++SRYE ENN P ++ T+ A D DL
Sbjct: 435 VIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDL 494
Query: 490 GINGKVSYRIQDS-----PVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQP- 543
G NG+V+Y I +S + V ID + G + A R ++EE++ F V A D G P
Sbjct: 495 GENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPK 554
Query: 544 MLASSVSVWVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGT 603
L S+ +V ++++D NDN P V+ P L + A +++ A +G
Sbjct: 555 QLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESG----------------- 597
Query: 604 DTPPLATHSSRPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNA 663
F +T I A D DSG N E +I +GNE ++FI++P + + NV+
Sbjct: 598 ------------FHVTRIRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVS-M 644
Query: 664 SSLIGSEWELEIVVEDQGSPPLQTRALLRVM---FVTSVDHLRDSARKPGALSMSMLTVI 720
S+ +EWEL ++++D+G+P L T+ LL+ M + SV ++ +L +SM+ +I
Sbjct: 645 DSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFEYAESVTSTAMTSVSQASLDVSMIIII 704
Query: 721 CLAVLLGIFGLILALFMSICRTEKKDNRAYNCREAESTYRQQPKRPQKHIQKADIHLVPV 780
L + + +I+ LF + C EKKD R+YNCR AESTY+ PKRP + I K DI LVP
Sbjct: 705 SLGAICAVLLVIMVLFATRCNREKKDTRSYNCRVAESTYQHHPKRPSRQIHKGDITLVPT 764
Query: 781 LRG 783
+ G
Sbjct: 765 ING 767
Score = 99.8 bits (247), Expect = 1e-20
Identities = 82/249 (32%), Positives = 118/249 (47%), Gaps = 42/249 (16%)
Query: 904 PASSATLRRQRHLNGKVSPEKESGPRQILRSLVRLSVAAFAERNPVEELTVDSPPVQQIS 963
P+SS TL R G++ + Q L SLV +S E +E LT +P V+Q+S
Sbjct: 779 PSSSPTLER-----GQMGSRQSHNSHQSLNSLVTISSNHVPENFSLE-LTHATPAVEQVS 832
Query: 964 QLLSLLHQGQFQPKPNHRGNKYLAKPGGSRSAIPDTDGPSARAGGQTDPEQEEGPLDPEE 1023
QLLS+LHQGQ+QP+P+ RGNKY R A+ D D S + G+ D E + D
Sbjct: 833 QLLSMLHQGQYQPRPSFRGNKY---SRSYRYALQDMDKFSLKDSGRGDSEAGDSDYDLGR 889
Query: 1024 DLSVKQLLEEELSSL------LDPSTGLALDR---LSAPDPAWMARLSLPLTTNYRDNVI 1074
D + +LL E S L + + L + L D WM L P +++YR N+
Sbjct: 890 DSPIDRLLGEGFSDLFLTDGRIPAAMRLCTEECRVLGHSDQCWMPPLPSP-SSDYRSNMF 948
Query: 1075 SP----------------------DAAATEEPRTFQTFGKAEAPELSPTGTRLASTFVSE 1112
P A + E+ ++F TFGK ++P TG S+ +SE
Sbjct: 949 IPGEEFPTQPQQQHPHQSLEDDAQPADSGEKKKSFSTFGK-DSPNDEDTGDTSTSSLLSE 1007
Query: 1113 MSSLLEMLL 1121
MSS+ + LL
Sbjct: 1008 MSSVFQRLL 1016
>gi|157426847 protocadherin 19 isoform a [Homo sapiens]
Length = 1101
Score = 485 bits (1249), Expect = e-137
Identities = 289/767 (37%), Positives = 435/767 (56%), Gaps = 53/767 (6%)
Query: 25 QEVTTLTVKYQVSEEVPSGTVIGKLSQ---ELGREERRRQAGAAFQVLQLPQALPIQVDS 81
Q + +KY V EE +GTVI +++ E G RQA +AF+V+ + ++
Sbjct: 18 QAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQA-SAFRVVSNSAPHLVDINP 76
Query: 82 EEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQE 141
GLL T +++DR+ LCRQ C++S +V+++ + + +++++ D+ND+ P FP + E
Sbjct: 77 SSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSS-MEICVIKVEIKDLNDNAPSFPAAQIE 135
Query: 142 LEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVVKE 201
LEISE+AS TRIPLD A DPD+G + TY L+P+E F L++ D ++ AEL+V K
Sbjct: 136 LEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFAELVVEKS 195
Query: 202 LDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAPGT 261
LDRE S + +TA D G+PP+ GT + + V DSNDN+P F+ES+ A+ + E++ P T
Sbjct: 196 LDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVSVPENSPPNT 255
Query: 262 LLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYEVD 321
+I+L A+DPD+G NG+V + ++ + F ID +G V + LDYE+ YE+D
Sbjct: 256 PVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEGHVYELD 315
Query: 322 VQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSL-VSEALPKDSFIALVMADD 380
VQA+DLGPN IPAHCKV + VLD NDN P I++ + + VSE+ P IALV D
Sbjct: 316 VQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVIALVRVSD 375
Query: 381 LDSGHNGLVHCWLSQELGH--FRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQ 438
DSG NG V C L LG+ FRL+ + +L + LDREQ +Y LT+ A+D G+
Sbjct: 376 RDSGLNGRVQCRL---LGNVPFRLQEYESFS-TILVDGRLDREQHDQYNLTIQARDGGVP 431
Query: 439 PLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSYR 498
L + K ++ I+D NDN P F K Y+V +ENN P +L+++ A D DLG+NG VSY+
Sbjct: 432 MLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSVSYQ 491
Query: 499 I-----QDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWV 553
I +D PV V+I+ N+G++ A RS N+E+ FEF+V+A+D G P L S+ +V V
Sbjct: 492 IVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNATVRV 551
Query: 554 SLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSS 613
+LD NDN P + P L +G A + + N+ G
Sbjct: 552 IILDVNDNTPVITAPPLINGTAEVYIPRNSGIG--------------------------- 584
Query: 614 RPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSEWEL 673
+L+T + A D D G NG Y + G+ F ++ G++ T S S +EL
Sbjct: 585 --YLVTVVKAEDYDEGENGRVTYDMTEGDRG-FFEIDQVNGEVRTTRTFGESS-KSSYEL 640
Query: 674 EIVVEDQGSPPLQTRALLRVMFVTSVDHLRDSARKPGALSMSMLTVICLAVLLGIFGLIL 733
+V D G L AL+ + ++D + G++++S++ +I L + GI + +
Sbjct: 641 IVVAHDHGKTSLSASALVLIYLSPALD----AQESMGSVNLSLIFIIALGSIAGILFVTM 696
Query: 734 ALFMSICRTEKKDNRAYNCREAESTYRQQPK-RPQKHIQKADIHLVP 779
C+ + K+ R YNCR AE +Y Q K +K I K DI LVP
Sbjct: 697 IFVAIKCKRDNKEIRTYNCRIAEYSYGHQKKSSKKKKISKNDIRLVP 743
>gi|157426845 protocadherin 19 isoform b [Homo sapiens]
Length = 1100
Score = 485 bits (1249), Expect = e-137
Identities = 289/767 (37%), Positives = 435/767 (56%), Gaps = 53/767 (6%)
Query: 25 QEVTTLTVKYQVSEEVPSGTVIGKLSQ---ELGREERRRQAGAAFQVLQLPQALPIQVDS 81
Q + +KY V EE +GTVI +++ E G RQA +AF+V+ + ++
Sbjct: 18 QAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQA-SAFRVVSNSAPHLVDINP 76
Query: 82 EEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQE 141
GLL T +++DR+ LCRQ C++S +V+++ + + +++++ D+ND+ P FP + E
Sbjct: 77 SSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSS-MEICVIKVEIKDLNDNAPSFPAAQIE 135
Query: 142 LEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVVKE 201
LEISE+AS TRIPLD A DPD+G + TY L+P+E F L++ D ++ AEL+V K
Sbjct: 136 LEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFAELVVEKS 195
Query: 202 LDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAPGT 261
LDRE S + +TA D G+PP+ GT + + V DSNDN+P F+ES+ A+ + E++ P T
Sbjct: 196 LDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVSVPENSPPNT 255
Query: 262 LLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYEVD 321
+I+L A+DPD+G NG+V + ++ + F ID +G V + LDYE+ YE+D
Sbjct: 256 PVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEGHVYELD 315
Query: 322 VQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSL-VSEALPKDSFIALVMADD 380
VQA+DLGPN IPAHCKV + VLD NDN P I++ + + VSE+ P IALV D
Sbjct: 316 VQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVIALVRVSD 375
Query: 381 LDSGHNGLVHCWLSQELGH--FRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQ 438
DSG NG V C L LG+ FRL+ + +L + LDREQ +Y LT+ A+D G+
Sbjct: 376 RDSGLNGRVQCRL---LGNVPFRLQEYESFS-TILVDGRLDREQHDQYNLTIQARDGGVP 431
Query: 439 PLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSYR 498
L + K ++ I+D NDN P F K Y+V +ENN P +L+++ A D DLG+NG VSY+
Sbjct: 432 MLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSVSYQ 491
Query: 499 I-----QDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWV 553
I +D PV V+I+ N+G++ A RS N+E+ FEF+V+A+D G P L S+ +V V
Sbjct: 492 IVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNATVRV 551
Query: 554 SLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSS 613
+LD NDN P + P L +G A + + N+ G
Sbjct: 552 IILDVNDNTPVITAPPLINGTAEVYIPRNSGIG--------------------------- 584
Query: 614 RPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSEWEL 673
+L+T + A D D G NG Y + G+ F ++ G++ T S S +EL
Sbjct: 585 --YLVTVVKAEDYDEGENGRVTYDMTEGDRG-FFEIDQVNGEVRTTRTFGESS-KSSYEL 640
Query: 674 EIVVEDQGSPPLQTRALLRVMFVTSVDHLRDSARKPGALSMSMLTVICLAVLLGIFGLIL 733
+V D G L AL+ + ++D + G++++S++ +I L + GI + +
Sbjct: 641 IVVAHDHGKTSLSASALVLIYLSPALD----AQESMGSVNLSLIFIIALGSIAGILFVTM 696
Query: 734 ALFMSICRTEKKDNRAYNCREAESTYRQQPK-RPQKHIQKADIHLVP 779
C+ + K+ R YNCR AE +Y Q K +K I K DI LVP
Sbjct: 697 IFVAIKCKRDNKEIRTYNCRIAEYSYGHQKKSSKKKKISKNDIRLVP 743
>gi|94538350 protocadherin 17 precursor [Homo sapiens]
Length = 1159
Score = 473 bits (1217), Expect = e-133
Identities = 312/803 (38%), Positives = 435/803 (54%), Gaps = 99/803 (12%)
Query: 27 VTTLTVKYQVSEEVPSGTVIGKLSQE------LGREERR---RQAGAAFQVLQLPQALPI 77
+T + Y V EE +GTVIG + ++ L ER R +++VL+ +
Sbjct: 16 LTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAPHLL 75
Query: 78 QVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATG-DLALIHVEIQVLDINDHQPRFP 136
VD++ GLL T +R+DRE LCR C +S +V A ++ +I VEIQ DIND+ P F
Sbjct: 76 DVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKVEIQ--DINDNAPSFS 133
Query: 137 KGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEH--FALDVIVGPDETKHA 194
+ E++ISE+A+ TR PL A DPD G N L TY L+ +H F LDV D TK
Sbjct: 134 SDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFP 193
Query: 195 ELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQ 254
EL++ K LDRE + LVLTA D G PP+S T + V V+DSNDNSP F S +E+
Sbjct: 194 ELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELP 253
Query: 255 EDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEK 314
E+A GT++I L ATD D+GPNGEV + S ++P V + FSID KTG + ++ LDYE+
Sbjct: 254 ENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEE 313
Query: 315 NPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIA 374
N E+DVQARDLGPNPIPAHCKV +K++D NDN PSI Q +L SEA P + IA
Sbjct: 314 NGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGAL-SEAAPPGTVIA 372
Query: 375 LVMADDLDSGHNGLVHCWLSQELGH--------------FRLKRTNGNTYMLLTNATLDR 420
LV D DSG NG + C + G F+L+ N Y ++T+ LDR
Sbjct: 373 LVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRPLDR 432
Query: 421 EQWPKYTLTLLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLI 480
E +Y +T++A+D G PL++ K +I+I D NDN P F K Y + ENN+P +L
Sbjct: 433 ETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGEYLG 492
Query: 481 TIKAHDADLGINGKVSYRIQDSPVAHL-----VAIDSNTGEVTAQRSLNYEEMAGFEFQV 535
++ A D DLG NG VSY I S + + V+++ G + A RS N+E+ FEF+V
Sbjct: 493 SVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKV 552
Query: 536 IAEDSGQPM-LASSVSVWVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIET 594
+A+DSG P L S+ +V V++LD NDNAP +V P L + A L V NA G
Sbjct: 553 LAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRNAGLG-------- 604
Query: 595 PNGLGPAGTDTPPLATHSSRPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTG 654
+L++T+ A D+D G +G Y I GN+ HLF ++P +G
Sbjct: 605 ---------------------YLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSG 643
Query: 655 QL------FVNVTNASSLIGSEWELEIVVEDQGSPPLQTRALLRVMFVT----------- 697
++ + +VT EL + V D G P L A L + V+
Sbjct: 644 EIRTLHPFWEDVTPVV-------ELVVKVTDHGKPTLSAVAKLIIRSVSGSLPEGVPRVN 696
Query: 698 SVDHLRDSARKPGALSMSMLTVICLAVLLGIFGLILALFMSICRTEKKDNRAYNCREAES 757
H D + P +++S +++I LA ++ I C+ E K+ R YNCR AE
Sbjct: 697 GEQHHWDMS-LPLIVTLSTISIILLAAMITI--------AVKCKRENKEIRTYNCRIAEY 747
Query: 758 TYRQ--QPKRPQKHIQKADIHLV 778
++ Q K +K I K DI LV
Sbjct: 748 SHPQLGGGKGKKKKINKNDIMLV 770
>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
Length = 1040
Score = 466 bits (1200), Expect = e-131
Identities = 294/802 (36%), Positives = 431/802 (53%), Gaps = 90/802 (11%)
Query: 34 YQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQVDSEEGLLSTGRRLD 93
Y V EE GT +G ++++LG + + A FQ + + + ++ E G+L ++D
Sbjct: 22 YTVQEEQEHGTFVGNIAEDLGLDITKLSA-RGFQTVPNSRTPYLDLNLETGVLYVNEKID 80
Query: 94 REQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQELEISESASLRTR 153
REQ+C+Q C++ +V L L VEI+VLDIND+ P FP+ + +EISESA+ TR
Sbjct: 81 REQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVEISESATPGTR 140
Query: 154 IPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVVKELDREIHSFFDLV 213
PL+ A DPD G N+L Y ++P+ +F+LDV D + AEL++ K LDRE + V
Sbjct: 141 FPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYV 200
Query: 214 LTAYDNGN----------------PP---KSGTSLVKVNVLDSNDNSPAFAESSLALEIQ 254
LTA D G PP ++GT+L+ + VLDSNDN PAF + + +
Sbjct: 201 LTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLP 260
Query: 255 EDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEK 314
E++ PGTL+I+L ATDPD+G NGEV + S H+ P + F + +TG++ + LDYE+
Sbjct: 261 ENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEE 320
Query: 315 NPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIA 374
+P Y+V VQA+DLGPN +PAHCKVL++VLD NDN P I ++++ VSE + +A
Sbjct: 321 SPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEI--SFSTVKEAVSEGAAPGTVVA 378
Query: 375 LVMADDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQD 434
L D DS NG V C L ++ FRLK + N Y ++T A LDRE YTLT++A+D
Sbjct: 379 LFSVTDRDSEENGQVQCELLGDVP-FRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARD 437
Query: 435 QGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGK 494
+G LS K + +Q+SD+NDNAP F + Y+V ENN+P ++ + A D D G N +
Sbjct: 438 RGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQ 497
Query: 495 VSY-----RIQDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPM-LASS 548
++Y +IQ V V+I+S G + A RS +YE++ F FQV A D+G P LA +
Sbjct: 498 LAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGN 557
Query: 549 VSVWVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPL 608
+V + ++D NDNAP +V P+ G GT +
Sbjct: 558 ATVNILIVDQNDNAPAIVAPLP----------------------------GRNGTPAREV 589
Query: 609 ATHSSRP-FLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQL-FVNVTNASSL 666
S+ P +LLT + A DAD G N YSI GNE +LF ++ TG+L A
Sbjct: 590 LPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRD 649
Query: 667 IGSEWELEIVVEDQGSPPLQTRALLRVMFVT---------------SVDHLRDSARKPG- 710
+EL I V D G PPL + A L V V S +H R S G
Sbjct: 650 PQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGE 709
Query: 711 -ALSMSMLTVICLAVLLGIFGLILALFMSICRTEKKDNRAYNCREAE------------- 756
+L ++++ +I L + IF L + + C+ EKK N Y C ++
Sbjct: 710 TSLDLTLILIIALGSVSFIFLLAMIVLAVRCQKEKKLN-IYTCLASDCCLCCCCCGGGGS 768
Query: 757 STYRQQPKRPQKHIQKADIHLV 778
+ +Q + +K + K+DI LV
Sbjct: 769 TCCGRQARARKKKLSKSDIMLV 790
Score = 85.5 bits (210), Expect = 3e-16
Identities = 83/336 (24%), Positives = 151/336 (44%), Gaps = 29/336 (8%)
Query: 26 EVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQVDS---E 82
E++ TVK VSE GTV+ S E Q +L +P ++ S
Sbjct: 357 EISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQC-----ELLGDVPFRLKSSFKN 411
Query: 83 EGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALI---HVEIQVLDINDHQPRFPKGE 139
+ T LDRE D ++ G+ AL +++QV D+ND+ PRF +
Sbjct: 412 YYTIVTEAPLDRE----AGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPV 467
Query: 140 QELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPD-ETKHAELIV 198
++ ++E+ I A D D G N Y++ + + V +++ L
Sbjct: 468 YDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYA 527
Query: 199 VKELDREIHSFFDLVLTAYDNGNPPK-SGTSLVKVNVLDSNDNSPAFA------ESSLAL 251
++ D E F + A D G+P +G + V + ++D NDN+PA + A
Sbjct: 528 LRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAR 587
Query: 252 EI-QEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPL 310
E+ A PG LL ++ A D D G N + + + + ++ F +D +TG++ R +
Sbjct: 588 EVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVR---GNEMNLFRMDWRTGELRTARRV 644
Query: 311 DYEKNP--AYEVDVQARDLGPNPIPAHCKVLIKVLD 344
+++P YE+ ++ RD G P+ + ++++++D
Sbjct: 645 PAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVD 680
>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
Length = 896
Score = 466 bits (1200), Expect = e-131
Identities = 294/802 (36%), Positives = 431/802 (53%), Gaps = 90/802 (11%)
Query: 34 YQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQVDSEEGLLSTGRRLD 93
Y V EE GT +G ++++LG + + A FQ + + + ++ E G+L ++D
Sbjct: 22 YTVQEEQEHGTFVGNIAEDLGLDITKLSA-RGFQTVPNSRTPYLDLNLETGVLYVNEKID 80
Query: 94 REQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQELEISESASLRTR 153
REQ+C+Q C++ +V L L VEI+VLDIND+ P FP+ + +EISESA+ TR
Sbjct: 81 REQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVEISESATPGTR 140
Query: 154 IPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVVKELDREIHSFFDLV 213
PL+ A DPD G N+L Y ++P+ +F+LDV D + AEL++ K LDRE + V
Sbjct: 141 FPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYV 200
Query: 214 LTAYDNGN----------------PP---KSGTSLVKVNVLDSNDNSPAFAESSLALEIQ 254
LTA D G PP ++GT+L+ + VLDSNDN PAF + + +
Sbjct: 201 LTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLP 260
Query: 255 EDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEK 314
E++ PGTL+I+L ATDPD+G NGEV + S H+ P + F + +TG++ + LDYE+
Sbjct: 261 ENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEE 320
Query: 315 NPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIA 374
+P Y+V VQA+DLGPN +PAHCKVL++VLD NDN P I ++++ VSE + +A
Sbjct: 321 SPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEI--SFSTVKEAVSEGAAPGTVVA 378
Query: 375 LVMADDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQD 434
L D DS NG V C L ++ FRLK + N Y ++T A LDRE YTLT++A+D
Sbjct: 379 LFSVTDRDSEENGQVQCELLGDVP-FRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARD 437
Query: 435 QGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGK 494
+G LS K + +Q+SD+NDNAP F + Y+V ENN+P ++ + A D D G N +
Sbjct: 438 RGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQ 497
Query: 495 VSY-----RIQDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPM-LASS 548
++Y +IQ V V+I+S G + A RS +YE++ F FQV A D+G P LA +
Sbjct: 498 LAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGN 557
Query: 549 VSVWVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPL 608
+V + ++D NDNAP +V P+ G GT +
Sbjct: 558 ATVNILIVDQNDNAPAIVAPLP----------------------------GRNGTPAREV 589
Query: 609 ATHSSRP-FLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQL-FVNVTNASSL 666
S+ P +LLT + A DAD G N YSI GNE +LF ++ TG+L A
Sbjct: 590 LPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRD 649
Query: 667 IGSEWELEIVVEDQGSPPLQTRALLRVMFVT---------------SVDHLRDSARKPG- 710
+EL I V D G PPL + A L V V S +H R S G
Sbjct: 650 PQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGE 709
Query: 711 -ALSMSMLTVICLAVLLGIFGLILALFMSICRTEKKDNRAYNCREAE------------- 756
+L ++++ +I L + IF L + + C+ EKK N Y C ++
Sbjct: 710 TSLDLTLILIIALGSVSFIFLLAMIVLAVRCQKEKKLN-IYTCLASDCCLCCCCCGGGGS 768
Query: 757 STYRQQPKRPQKHIQKADIHLV 778
+ +Q + +K + K+DI LV
Sbjct: 769 TCCGRQARARKKKLSKSDIMLV 790
Score = 85.5 bits (210), Expect = 3e-16
Identities = 83/336 (24%), Positives = 151/336 (44%), Gaps = 29/336 (8%)
Query: 26 EVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQVDS---E 82
E++ TVK VSE GTV+ S E Q +L +P ++ S
Sbjct: 357 EISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQC-----ELLGDVPFRLKSSFKN 411
Query: 83 EGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALI---HVEIQVLDINDHQPRFPKGE 139
+ T LDRE D ++ G+ AL +++QV D+ND+ PRF +
Sbjct: 412 YYTIVTEAPLDRE----AGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPV 467
Query: 140 QELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPD-ETKHAELIV 198
++ ++E+ I A D D G N Y++ + + V +++ L
Sbjct: 468 YDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYA 527
Query: 199 VKELDREIHSFFDLVLTAYDNGNPPK-SGTSLVKVNVLDSNDNSPAFA------ESSLAL 251
++ D E F + A D G+P +G + V + ++D NDN+PA + A
Sbjct: 528 LRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAR 587
Query: 252 EI-QEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPL 310
E+ A PG LL ++ A D D G N + + + + ++ F +D +TG++ R +
Sbjct: 588 EVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVR---GNEMNLFRMDWRTGELRTARRV 644
Query: 311 DYEKNP--AYEVDVQARDLGPNPIPAHCKVLIKVLD 344
+++P YE+ ++ RD G P+ + ++++++D
Sbjct: 645 PAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVD 680
>gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor
[Homo sapiens]
Length = 1007
Score = 440 bits (1132), Expect = e-123
Identities = 275/749 (36%), Positives = 410/749 (54%), Gaps = 58/749 (7%)
Query: 4 LLQLLLGLLGPGGYLFLLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAG 63
LL LLL L GP ++Y V EE G ++G +++ LG E RR G
Sbjct: 29 LLLLLLLLPGPAAS-------------QLRYSVPEEQAPGALVGNVARALGLELRRLGPG 75
Query: 64 AA-FQVLQLPQALPIQVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVE 122
L P +++D G L R+DRE LC Q CL+S +VLA +A+ VE
Sbjct: 76 CLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVE 135
Query: 123 IQVLDINDHQPRFPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFAL 182
+++LDIND+ PRFP+ +L++SES + R ++ A DPD G N++ TY LSPSEHF L
Sbjct: 136 VEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFEL 195
Query: 183 DVIVGPDETKHAELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSP 242
D+ + +K EL++ K LDRE + LVLTA D G P +SGT+ + V VLD+NDNSP
Sbjct: 196 DLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSP 255
Query: 243 AFAESSLALEIQEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTG 302
AF +S+ ++++ED+ PGTL++KL A+DPD+G NGE+ + LS + FSIDA TG
Sbjct: 256 AFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTG 315
Query: 303 QVILRRPLDYEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSL 362
+V + LDYE+ +Y++ VQA D GP P+ HCKVL+ ++DVNDN P + +T P
Sbjct: 316 EVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSP-- 373
Query: 363 VSEALPKDSFIALVMADDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQ 422
V E ++ +A++ +D DSG N V L L FRL GN+Y L+ + LDRE+
Sbjct: 374 VPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATL-PFRLNGF-GNSYTLVVSGPLDRER 431
Query: 423 WPKYTLTLLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITI 482
Y +T+ A D G+ L++ + L ++ISDINDN P F + Y + +ENNLP + L T+
Sbjct: 432 VAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTV 491
Query: 483 KAHDADLGINGKVSY-----RIQDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIA 537
+A D D N +V+Y IQ PV V+I+S +G + A S +YE+ F V A
Sbjct: 492 QATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEA 551
Query: 538 EDSGQPMLASSVSVWVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNG 597
+D G P L+S+V+ V ++D ND+AP ++ P + N+S +VP P G
Sbjct: 552 QDKGSPPLSSTVTANVYVVDMNDHAPHILYPTST----------NSSAAFEMVPRTAPAG 601
Query: 598 LGPAGTDTPPLATHSSRPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLF 657
+L+T ++A D+DSG N Y + ++ LF + HTG++
Sbjct: 602 ------------------YLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEI- 642
Query: 658 VNVTNASSLIGSEWELEIVVEDQGSPPLQTRALLRVMFVTSVDHL----RDSARKPGALS 713
GS + L +VV D G P L + V V V + + + P S
Sbjct: 643 RTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYS 702
Query: 714 -MSMLTVICLAVLLGIFGLILALFMSICR 741
+++ +I L+ + IF L+ + +SI +
Sbjct: 703 EITLYLIIALSTVSFIF-LLTIIILSIIK 730
>gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precursor
[Homo sapiens]
Length = 884
Score = 440 bits (1132), Expect = e-123
Identities = 275/749 (36%), Positives = 410/749 (54%), Gaps = 58/749 (7%)
Query: 4 LLQLLLGLLGPGGYLFLLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAG 63
LL LLL L GP ++Y V EE G ++G +++ LG E RR G
Sbjct: 29 LLLLLLLLPGPAAS-------------QLRYSVPEEQAPGALVGNVARALGLELRRLGPG 75
Query: 64 AA-FQVLQLPQALPIQVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVE 122
L P +++D G L R+DRE LC Q CL+S +VLA +A+ VE
Sbjct: 76 CLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVE 135
Query: 123 IQVLDINDHQPRFPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFAL 182
+++LDIND+ PRFP+ +L++SES + R ++ A DPD G N++ TY LSPSEHF L
Sbjct: 136 VEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFEL 195
Query: 183 DVIVGPDETKHAELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSP 242
D+ + +K EL++ K LDRE + LVLTA D G P +SGT+ + V VLD+NDNSP
Sbjct: 196 DLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSP 255
Query: 243 AFAESSLALEIQEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTG 302
AF +S+ ++++ED+ PGTL++KL A+DPD+G NGE+ + LS + FSIDA TG
Sbjct: 256 AFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTG 315
Query: 303 QVILRRPLDYEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSL 362
+V + LDYE+ +Y++ VQA D GP P+ HCKVL+ ++DVNDN P + +T P
Sbjct: 316 EVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSP-- 373
Query: 363 VSEALPKDSFIALVMADDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQ 422
V E ++ +A++ +D DSG N V L L FRL GN+Y L+ + LDRE+
Sbjct: 374 VPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATL-PFRLNGF-GNSYTLVVSGPLDRER 431
Query: 423 WPKYTLTLLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITI 482
Y +T+ A D G+ L++ + L ++ISDINDN P F + Y + +ENNLP + L T+
Sbjct: 432 VAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTV 491
Query: 483 KAHDADLGINGKVSY-----RIQDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIA 537
+A D D N +V+Y IQ PV V+I+S +G + A S +YE+ F V A
Sbjct: 492 QATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEA 551
Query: 538 EDSGQPMLASSVSVWVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNG 597
+D G P L+S+V+ V ++D ND+AP ++ P + N+S +VP P G
Sbjct: 552 QDKGSPPLSSTVTANVYVVDMNDHAPHILYPTST----------NSSAAFEMVPRTAPAG 601
Query: 598 LGPAGTDTPPLATHSSRPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLF 657
+L+T ++A D+DSG N Y + ++ LF + HTG++
Sbjct: 602 ------------------YLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEI- 642
Query: 658 VNVTNASSLIGSEWELEIVVEDQGSPPLQTRALLRVMFVTSVDHL----RDSARKPGALS 713
GS + L +VV D G P L + V V V + + + P S
Sbjct: 643 RTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYS 702
Query: 714 -MSMLTVICLAVLLGIFGLILALFMSICR 741
+++ +I L+ + IF L+ + +SI +
Sbjct: 703 EITLYLIIALSTVSFIF-LLTIIILSIIK 730
>gi|14270508 protocadherin gamma subfamily B, 7 isoform 2 precursor
[Homo sapiens]
Length = 808
Score = 419 bits (1078), Expect = e-117
Identities = 257/748 (34%), Positives = 402/748 (53%), Gaps = 47/748 (6%)
Query: 32 VKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQVDSEEGLLSTGRR 91
++Y + EE+ G+V+G L+++LG A ++ + L VD++ G L R
Sbjct: 33 IRYSIPEELAKGSVVGNLAKDLGLSVLDVSAR---ELRVSAEKLHFSVDAQSGDLLVKDR 89
Query: 92 LDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQELEISESASLR 151
+DREQ+C++ C + + + L + HV + + D+NDH P+F K E LEISES SL
Sbjct: 90 IDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKDEINLEISESVSLG 149
Query: 152 TRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVVKELDREIHSFFD 211
L+ A DPD N+L Y LSP+E+F+L PD K+ EL++ K LDRE S
Sbjct: 150 MGTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNPDGGKYPELVLQKTLDRETQSAHH 209
Query: 212 LVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAPGTLLIKLTATDP 271
LVLTA D G+PP+SGT+ +++ V+D+NDN P F++ + ++ED PGT ++++ ATD
Sbjct: 210 LVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVSLREDVPPGTSILRVKATDQ 269
Query: 272 DQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYEVDVQARDLGPNP 331
D+G N E+ + + + FS+D TG ++ ++PLD+E+ Y ++++A+D G
Sbjct: 270 DEGINSEITYSFFG-VADKAQHVFSLDYTTGNILTQQPLDFEEVERYTINIEAKDRGS-- 326
Query: 332 IPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMADDLDSGHNGLVHC 391
+ CKV+++V+D NDN P I +T S + E P +AL D DSG NG V C
Sbjct: 327 LSTRCKVIVEVVDENDNSPEIIITSLSDQ--IMEDSPPGVVVALFKTRDQDSGENGEVRC 384
Query: 392 WLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQPLSAKKQLSIQIS 451
LS+ + F++ ++ N Y L+T+ LDREQ P+Y +T+ A D+G PLS+ K +++ I+
Sbjct: 385 SLSRGVP-FKIHSSSNNYYKLVTDEALDREQTPEYNVTIAATDRGKPPLSSSKTITLHIT 443
Query: 452 DINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSYRI-----QDSPVAH 506
D+NDNAPVF +S Y V ENN P + + A D D G+NG+VSY + + ++
Sbjct: 444 DVNDNAPVFGQSAYLVHVPENNQPGASIAQVSASDPDFGLNGRVSYSLIASDLESRTLSS 503
Query: 507 LVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVSLLDANDNAPEVV 566
V++ + +G V AQR+ ++E++ FE + A D G P L+++VS+ V + D NDNAP V+
Sbjct: 504 YVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVL 563
Query: 567 QPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSSRPFLLTTIVARDA 626
P L G A DT P A +L+T +VA DA
Sbjct: 564 YPALGPD-------------------------GSALFDTVPRAAQPG--YLVTKVVAVDA 596
Query: 627 DSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSEWELEIVVEDQGSPPLQ 686
DSG N Y + +E LF L TG++ + V L + V D G PPL
Sbjct: 597 DSGHNAWLSYHVVQASEPGLFSLGLRTGEVRM-VRALGDKDSVRQRLLVAVRDGGQPPLS 655
Query: 687 TRALLRVMFVTSVDH-LRDSARKP----GALSMSMLTVICLAVLLGIFGLILALFMSICR 741
A L ++F S+ L D + P M V+ LA++ +F L + L +++
Sbjct: 656 ATATLHLVFADSLQEVLPDFSDHPTPSDSQAEMQFYLVVALALISVLFLLAVILAIALRL 715
Query: 742 TEKKDNRAYNCREAESTYRQQPKRPQKH 769
+ A +C E+ + P P +
Sbjct: 716 RQSFSPTAGDCFESVLCSKSGPVGPPNY 743
>gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precursor
[Homo sapiens]
Length = 929
Score = 419 bits (1078), Expect = e-117
Identities = 257/748 (34%), Positives = 402/748 (53%), Gaps = 47/748 (6%)
Query: 32 VKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQVDSEEGLLSTGRR 91
++Y + EE+ G+V+G L+++LG A ++ + L VD++ G L R
Sbjct: 33 IRYSIPEELAKGSVVGNLAKDLGLSVLDVSAR---ELRVSAEKLHFSVDAQSGDLLVKDR 89
Query: 92 LDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQELEISESASLR 151
+DREQ+C++ C + + + L + HV + + D+NDH P+F K E LEISES SL
Sbjct: 90 IDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKDEINLEISESVSLG 149
Query: 152 TRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVVKELDREIHSFFD 211
L+ A DPD N+L Y LSP+E+F+L PD K+ EL++ K LDRE S
Sbjct: 150 MGTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNPDGGKYPELVLQKTLDRETQSAHH 209
Query: 212 LVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAPGTLLIKLTATDP 271
LVLTA D G+PP+SGT+ +++ V+D+NDN P F++ + ++ED PGT ++++ ATD
Sbjct: 210 LVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVSLREDVPPGTSILRVKATDQ 269
Query: 272 DQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYEVDVQARDLGPNP 331
D+G N E+ + + + FS+D TG ++ ++PLD+E+ Y ++++A+D G
Sbjct: 270 DEGINSEITYSFFG-VADKAQHVFSLDYTTGNILTQQPLDFEEVERYTINIEAKDRGS-- 326
Query: 332 IPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMADDLDSGHNGLVHC 391
+ CKV+++V+D NDN P I +T S + E P +AL D DSG NG V C
Sbjct: 327 LSTRCKVIVEVVDENDNSPEIIITSLSDQ--IMEDSPPGVVVALFKTRDQDSGENGEVRC 384
Query: 392 WLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQPLSAKKQLSIQIS 451
LS+ + F++ ++ N Y L+T+ LDREQ P+Y +T+ A D+G PLS+ K +++ I+
Sbjct: 385 SLSRGVP-FKIHSSSNNYYKLVTDEALDREQTPEYNVTIAATDRGKPPLSSSKTITLHIT 443
Query: 452 DINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSYRI-----QDSPVAH 506
D+NDNAPVF +S Y V ENN P + + A D D G+NG+VSY + + ++
Sbjct: 444 DVNDNAPVFGQSAYLVHVPENNQPGASIAQVSASDPDFGLNGRVSYSLIASDLESRTLSS 503
Query: 507 LVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVSLLDANDNAPEVV 566
V++ + +G V AQR+ ++E++ FE + A D G P L+++VS+ V + D NDNAP V+
Sbjct: 504 YVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVL 563
Query: 567 QPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSSRPFLLTTIVARDA 626
P L G A DT P A +L+T +VA DA
Sbjct: 564 YPALGPD-------------------------GSALFDTVPRAAQPG--YLVTKVVAVDA 596
Query: 627 DSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSEWELEIVVEDQGSPPLQ 686
DSG N Y + +E LF L TG++ + V L + V D G PPL
Sbjct: 597 DSGHNAWLSYHVVQASEPGLFSLGLRTGEVRM-VRALGDKDSVRQRLLVAVRDGGQPPLS 655
Query: 687 TRALLRVMFVTSVDH-LRDSARKP----GALSMSMLTVICLAVLLGIFGLILALFMSICR 741
A L ++F S+ L D + P M V+ LA++ +F L + L +++
Sbjct: 656 ATATLHLVFADSLQEVLPDFSDHPTPSDSQAEMQFYLVVALALISVLFLLAVILAIALRL 715
Query: 742 TEKKDNRAYNCREAESTYRQQPKRPQKH 769
+ A +C E+ + P P +
Sbjct: 716 RQSFSPTAGDCFESVLCSKSGPVGPPNY 743
>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 416 bits (1070), Expect = e-116
Identities = 258/726 (35%), Positives = 396/726 (54%), Gaps = 49/726 (6%)
Query: 20 LLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQV 79
LLG E ++Y V EE+ G+ +G +S++LG E R A +++ + +
Sbjct: 19 LLGTLWETGCTQIRYSVPEELEKGSRVGDISRDLGLEPREL-AERGVRIIPRGRTQLFAL 77
Query: 80 DSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGE 139
+ G L T R+DRE+LC C ++ D+L + + VE++V DIND+ P F + E
Sbjct: 78 NPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRESE 137
Query: 140 QELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVV 199
E++ISE+A+ R PL A DPD G N+L +Y LSP+ HF+L V G D +K+ EL++
Sbjct: 138 LEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGSKYPELVLK 197
Query: 200 KELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAP 259
+ LDRE + LVLTA D G+P ++GT+ ++V VLD+NDN+PAFA+ + E+ A
Sbjct: 198 RALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPENLAL 257
Query: 260 GTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYE 319
GT L+ + ATDPD+G N EV + +++ + F +D +G + LD+E++ Y+
Sbjct: 258 GTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTIGELDHEESGFYQ 316
Query: 320 VDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMAD 379
++VQA D A KVLI VLDVNDN P + +T S S V E P+ + IAL+ +
Sbjct: 317 MEVQAMDNA--GYSARAKVLITVLDVNDNAPEVVLT--SLASSVPENSPRGTLIALLNVN 372
Query: 380 DLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQP 439
D DS NG V C++ L F+L+++ GN Y L+T+ LDREQ P Y +T+ A D+G P
Sbjct: 373 DQDSEENGQVICFIQGNL-PFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGTPP 431
Query: 440 LSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSY-- 497
LS + +S+ ++D NDN PVF ++ Y ENN + L+++ AHD D N +++Y
Sbjct: 432 LSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITYSL 491
Query: 498 ---RIQDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVS 554
IQ + ++ V+I+S+TG + A S +YE+ + +V+A D+G P L+S+VS+ +
Sbjct: 492 AENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLSLF 551
Query: 555 LLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSSR 614
+LD NDNAPE++ P L + STG L P G
Sbjct: 552 VLDQNDNAPEILYPALP---------TDGSTGVELAPRSAEPG----------------- 585
Query: 615 PFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSE---W 671
+L+T +VA D DSG N Y + +E LF + HTG+ V A +L+ +
Sbjct: 586 -YLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGE----VRTARALLDRDALKQ 640
Query: 672 ELEIVVEDQGSPPLQTRALLRVMFVTSVDHL---RDSARKPGALSMSMLTVICLAVLLGI 728
L + V+D G PPL L V S+ + S P S LT+ + + +
Sbjct: 641 SLVVAVQDHGQPPLSATVTLTVAVADSIPQVLADLGSLESPANSETSDLTLYLVVAVAAV 700
Query: 729 FGLILA 734
+ LA
Sbjct: 701 SCVFLA 706
>gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 416 bits (1070), Expect = e-116
Identities = 258/726 (35%), Positives = 396/726 (54%), Gaps = 49/726 (6%)
Query: 20 LLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQV 79
LLG E ++Y V EE+ G+ +G +S++LG E R A +++ + +
Sbjct: 19 LLGTLWETGCTQIRYSVPEELEKGSRVGDISRDLGLEPREL-AERGVRIIPRGRTQLFAL 77
Query: 80 DSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGE 139
+ G L T R+DRE+LC C ++ D+L + + VE++V DIND+ P F + E
Sbjct: 78 NPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRESE 137
Query: 140 QELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVV 199
E++ISE+A+ R PL A DPD G N+L +Y LSP+ HF+L V G D +K+ EL++
Sbjct: 138 LEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGSKYPELVLK 197
Query: 200 KELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAP 259
+ LDRE + LVLTA D G+P ++GT+ ++V VLD+NDN+PAFA+ + E+ A
Sbjct: 198 RALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPENLAL 257
Query: 260 GTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYE 319
GT L+ + ATDPD+G N EV + +++ + F +D +G + LD+E++ Y+
Sbjct: 258 GTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTIGELDHEESGFYQ 316
Query: 320 VDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMAD 379
++VQA D A KVLI VLDVNDN P + +T S S V E P+ + IAL+ +
Sbjct: 317 MEVQAMDNA--GYSARAKVLITVLDVNDNAPEVVLT--SLASSVPENSPRGTLIALLNVN 372
Query: 380 DLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQP 439
D DS NG V C++ L F+L+++ GN Y L+T+ LDREQ P Y +T+ A D+G P
Sbjct: 373 DQDSEENGQVICFIQGNL-PFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGTPP 431
Query: 440 LSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSY-- 497
LS + +S+ ++D NDN PVF ++ Y ENN + L+++ AHD D N +++Y
Sbjct: 432 LSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITYSL 491
Query: 498 ---RIQDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVS 554
IQ + ++ V+I+S+TG + A S +YE+ + +V+A D+G P L+S+VS+ +
Sbjct: 492 AENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLSLF 551
Query: 555 LLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSSR 614
+LD NDNAPE++ P L + STG L P G
Sbjct: 552 VLDQNDNAPEILYPALP---------TDGSTGVELAPRSAEPG----------------- 585
Query: 615 PFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSE---W 671
+L+T +VA D DSG N Y + +E LF + HTG+ V A +L+ +
Sbjct: 586 -YLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGE----VRTARALLDRDALKQ 640
Query: 672 ELEIVVEDQGSPPLQTRALLRVMFVTSVDHL---RDSARKPGALSMSMLTVICLAVLLGI 728
L + V+D G PPL L V S+ + S P S LT+ + + +
Sbjct: 641 SLVVAVQDHGQPPLSATVTLTVAVADSIPQVLADLGSLESPANSETSDLTLYLVVAVAAV 700
Query: 729 FGLILA 734
+ LA
Sbjct: 701 SCVFLA 706
>gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 416 bits (1070), Expect = e-116
Identities = 249/712 (34%), Positives = 387/712 (54%), Gaps = 52/712 (7%)
Query: 32 VKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQVDSEEGLLSTGRR 91
+ Y V EE G+ +G ++++LG + + G +++ + ++ G L T RR
Sbjct: 31 IHYSVPEETDKGSFVGNIAKDLGLQPQELADGGV-RIVSRGRMPLFALNPRSGSLITARR 89
Query: 92 LDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQELEISESASLR 151
+DRE+LC Q PCLVSF++L + L VE++++DIND+ P+F E E +++E +
Sbjct: 90 IDREELCAQSMPCLVSFNILVEDKMKLFPVEVEIIDINDNTPQFQLEELEFKMNEITTPG 149
Query: 152 TRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVVKELDREIHSFFD 211
TR+ L D D G N+L +Y LS + HF+LDV G D +H E+++ LDRE +
Sbjct: 150 TRVSLPFGQDLDVGMNSLQSYQLSSNPHFSLDVQQGADGPQHPEMVLQSPLDREEEAVHH 209
Query: 212 LVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAPGTLLIKLTATDP 271
L+LTA D G P +SGT + + V+D+NDN PAF ++ + + E+ GT L+ + ATDP
Sbjct: 210 LILTASDGGEPVRSGTLRIYIQVVDANDNPPAFTQAQYHINVPENVPLGTQLLMVNATDP 269
Query: 272 DQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYEVDVQARDLGPNP 331
D+G NGEV + ++ V F +D+ TG++ + PLD+E+ Y ++VQA+D
Sbjct: 270 DEGANGEVTYSF-HNVDHRVAQIFRLDSYTGEISNKEPLDFEEYKMYSMEVQAQD--GAG 326
Query: 332 IPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMADDLDSGHNGLVHC 391
+ A KVLIKVLDVNDN P + +T S + V E P + IAL+ D DSG NG C
Sbjct: 327 LMAKVKVLIKVLDVNDNAPEVTIT--SVTTAVPENFPPGTIIALISVHDQDSGDNGYTTC 384
Query: 392 WLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQPLSAKKQLSIQIS 451
++ L F+L++ N Y L+T TLDRE Y +T+ A DQG LS + +S+ ++
Sbjct: 385 FIPGNL-PFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALSTETHISLLVT 443
Query: 452 DINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSY-----RIQDSPVAH 506
DINDN+PVF + Y ENN + +++AHD D N +++Y IQ +P++
Sbjct: 444 DINDNSPVFHQDSYSAYIPENNPRGASIFSVRAHDLDSNENAQITYSLIEDTIQGAPLSA 503
Query: 507 LVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVSLLDANDNAPEVV 566
++I+S+TG + A RS +YE+ + +V+A DSG P L+S+VS+ + LLD NDNAPE++
Sbjct: 504 YLSINSDTGVLYALRSFDYEQFRDMQLKVMARDSGDPPLSSNVSLSLFLLDQNDNAPEIL 563
Query: 567 QPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSSRPFLLTTIVARDA 626
P L + STG L P+ G +L+T +VA D
Sbjct: 564 YPALP---------TDGSTGVELAPLSAEPG------------------YLVTKVVAVDR 596
Query: 627 DSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSE---WELEIVVEDQGSP 683
DSG N Y + +E LF + HTG+ V A +L+ + L + V+D G P
Sbjct: 597 DSGQNAWLSYRLLKASEPGLFSVGLHTGE----VRTARALLDRDALKQSLVVAVQDHGQP 652
Query: 684 PLQTRALLRVMFVTSVDHL------RDSARKPGALSMSMLTVICLAVLLGIF 729
PL L V + + + + KP +++ V+ A + +F
Sbjct: 653 PLSATVTLTVAVADRISDILADLGSLEPSAKPNDSDLTLYLVVAAAAVSCVF 704
Score = 89.4 bits (220), Expect = 2e-17
Identities = 102/366 (27%), Positives = 149/366 (40%), Gaps = 32/366 (8%)
Query: 26 EVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQVDSEEGL 85
EVT +V V E P GT+I +S ++ F LP L VD+ L
Sbjct: 346 EVTITSVTTAVPENFPPGTIIALISVH-DQDSGDNGYTTCFIPGNLPFKLEKLVDNYYRL 404
Query: 86 LSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQELEIS 145
+ T R LDRE L ++ + + D H+ + V DIND+ P F + I
Sbjct: 405 V-TERTLDRE-LISGYNITITAIDQGTPALSTETHISLLVTDINDNSPVFHQDSYSAYIP 462
Query: 146 ESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAE-------LIV 198
E+ I RA D D+ N TY+L D I G + + L
Sbjct: 463 ENNPRGASIFSVRAHDLDSNENAQITYSLIE------DTIQGAPLSAYLSINSDTGVLYA 516
Query: 199 VKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAF------AESSLALE 252
++ D E L + A D+G+PP S + + +LD NDN+P + S +E
Sbjct: 517 LRSFDYEQFRDMQLKVMARDSGDPPLSSNVSLSLFLLDQNDNAPEILYPALPTDGSTGVE 576
Query: 253 IQE-DAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLD 311
+ A PG L+ K+ A D D G N + + L K P + FS+ TG+V R L
Sbjct: 577 LAPLSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGL---FSVGLHTGEVRTARALL 633
Query: 312 YEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDS 371
+ V +D G P+ A + + V D +I A SL A P DS
Sbjct: 634 DRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRISDI------LADLGSLEPSAKPNDS 687
Query: 372 FIALVM 377
+ L +
Sbjct: 688 DLTLYL 693
>gi|14196459 protocadherin gamma subfamily A, 1 isoform 2 precursor
[Homo sapiens]
Length = 823
Score = 416 bits (1070), Expect = e-116
Identities = 249/712 (34%), Positives = 387/712 (54%), Gaps = 52/712 (7%)
Query: 32 VKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQVDSEEGLLSTGRR 91
+ Y V EE G+ +G ++++LG + + G +++ + ++ G L T RR
Sbjct: 31 IHYSVPEETDKGSFVGNIAKDLGLQPQELADGGV-RIVSRGRMPLFALNPRSGSLITARR 89
Query: 92 LDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQELEISESASLR 151
+DRE+LC Q PCLVSF++L + L VE++++DIND+ P+F E E +++E +
Sbjct: 90 IDREELCAQSMPCLVSFNILVEDKMKLFPVEVEIIDINDNTPQFQLEELEFKMNEITTPG 149
Query: 152 TRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVVKELDREIHSFFD 211
TR+ L D D G N+L +Y LS + HF+LDV G D +H E+++ LDRE +
Sbjct: 150 TRVSLPFGQDLDVGMNSLQSYQLSSNPHFSLDVQQGADGPQHPEMVLQSPLDREEEAVHH 209
Query: 212 LVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAPGTLLIKLTATDP 271
L+LTA D G P +SGT + + V+D+NDN PAF ++ + + E+ GT L+ + ATDP
Sbjct: 210 LILTASDGGEPVRSGTLRIYIQVVDANDNPPAFTQAQYHINVPENVPLGTQLLMVNATDP 269
Query: 272 DQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYEVDVQARDLGPNP 331
D+G NGEV + ++ V F +D+ TG++ + PLD+E+ Y ++VQA+D
Sbjct: 270 DEGANGEVTYSF-HNVDHRVAQIFRLDSYTGEISNKEPLDFEEYKMYSMEVQAQD--GAG 326
Query: 332 IPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMADDLDSGHNGLVHC 391
+ A KVLIKVLDVNDN P + +T S + V E P + IAL+ D DSG NG C
Sbjct: 327 LMAKVKVLIKVLDVNDNAPEVTIT--SVTTAVPENFPPGTIIALISVHDQDSGDNGYTTC 384
Query: 392 WLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQPLSAKKQLSIQIS 451
++ L F+L++ N Y L+T TLDRE Y +T+ A DQG LS + +S+ ++
Sbjct: 385 FIPGNL-PFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALSTETHISLLVT 443
Query: 452 DINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSY-----RIQDSPVAH 506
DINDN+PVF + Y ENN + +++AHD D N +++Y IQ +P++
Sbjct: 444 DINDNSPVFHQDSYSAYIPENNPRGASIFSVRAHDLDSNENAQITYSLIEDTIQGAPLSA 503
Query: 507 LVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVSLLDANDNAPEVV 566
++I+S+TG + A RS +YE+ + +V+A DSG P L+S+VS+ + LLD NDNAPE++
Sbjct: 504 YLSINSDTGVLYALRSFDYEQFRDMQLKVMARDSGDPPLSSNVSLSLFLLDQNDNAPEIL 563
Query: 567 QPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSSRPFLLTTIVARDA 626
P L + STG L P+ G +L+T +VA D
Sbjct: 564 YPALP---------TDGSTGVELAPLSAEPG------------------YLVTKVVAVDR 596
Query: 627 DSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSE---WELEIVVEDQGSP 683
DSG N Y + +E LF + HTG+ V A +L+ + L + V+D G P
Sbjct: 597 DSGQNAWLSYRLLKASEPGLFSVGLHTGE----VRTARALLDRDALKQSLVVAVQDHGQP 652
Query: 684 PLQTRALLRVMFVTSVDHL------RDSARKPGALSMSMLTVICLAVLLGIF 729
PL L V + + + + KP +++ V+ A + +F
Sbjct: 653 PLSATVTLTVAVADRISDILADLGSLEPSAKPNDSDLTLYLVVAAAAVSCVF 704
Score = 89.4 bits (220), Expect = 2e-17
Identities = 102/366 (27%), Positives = 149/366 (40%), Gaps = 32/366 (8%)
Query: 26 EVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQVDSEEGL 85
EVT +V V E P GT+I +S ++ F LP L VD+ L
Sbjct: 346 EVTITSVTTAVPENFPPGTIIALISVH-DQDSGDNGYTTCFIPGNLPFKLEKLVDNYYRL 404
Query: 86 LSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQELEIS 145
+ T R LDRE L ++ + + D H+ + V DIND+ P F + I
Sbjct: 405 V-TERTLDRE-LISGYNITITAIDQGTPALSTETHISLLVTDINDNSPVFHQDSYSAYIP 462
Query: 146 ESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAE-------LIV 198
E+ I RA D D+ N TY+L D I G + + L
Sbjct: 463 ENNPRGASIFSVRAHDLDSNENAQITYSLIE------DTIQGAPLSAYLSINSDTGVLYA 516
Query: 199 VKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAF------AESSLALE 252
++ D E L + A D+G+PP S + + +LD NDN+P + S +E
Sbjct: 517 LRSFDYEQFRDMQLKVMARDSGDPPLSSNVSLSLFLLDQNDNAPEILYPALPTDGSTGVE 576
Query: 253 IQE-DAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLD 311
+ A PG L+ K+ A D D G N + + L K P + FS+ TG+V R L
Sbjct: 577 LAPLSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGL---FSVGLHTGEVRTARALL 633
Query: 312 YEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDS 371
+ V +D G P+ A + + V D +I A SL A P DS
Sbjct: 634 DRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRISDI------LADLGSLEPSAKPNDS 687
Query: 372 FIALVM 377
+ L +
Sbjct: 688 DLTLYL 693
>gi|14270499 protocadherin gamma subfamily B, 4 isoform 2 precursor
[Homo sapiens]
Length = 803
Score = 414 bits (1064), Expect = e-115
Identities = 264/750 (35%), Positives = 400/750 (53%), Gaps = 75/750 (10%)
Query: 17 YLFLLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLP---- 72
+LFLL ++Y++ EE+P G+V+G L+ +LG F V +LP
Sbjct: 18 FLFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLG-----------FSVQELPTRKL 66
Query: 73 ----QALPIQVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDI 128
+ V +E G L RLDRE++C + C + F+ +A L HV +++ DI
Sbjct: 67 RVSSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHVNVEIEDI 126
Query: 129 NDHQPRFPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGP 188
NDH P+F + EL+ISESA TR L A D D G NTL Y LSPS+HF+L
Sbjct: 127 NDHTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKS 186
Query: 189 DETKHAELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESS 248
D +K+ E+++ LDRE + L LTA D G PP S T+ + V V D+NDN+P F++
Sbjct: 187 DGSKYPEMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDV 246
Query: 249 LALEIQEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRR 308
+ + E+ PGT ++++TATD D+G N E+ F S+ + F +++ TG++ +
Sbjct: 247 YRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSE---ASQITQFDLNSNTGEITVLN 303
Query: 309 PLDYEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALP 368
LD+E+ Y + ++ARD G + A C V ++V+D NDN P V + S P+L+ E
Sbjct: 304 TLDFEEVKEYSIVLEARDGGG--MIAQCTVEVEVIDENDNAPE--VIFQSLPNLIMEDAE 359
Query: 369 KDSFIALVMADDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTL 428
+ IAL+ D DS HNG V C L ++ F++ ++ NTY L+T+A LDREQ P+Y +
Sbjct: 360 LGTHIALLKVRDKDSRHNGEVTCKLEGDVP-FKILTSSRNTYKLVTDAVLDREQNPEYNI 418
Query: 429 TLLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDAD 488
T+ A D+G PLS+ +++ I D+NDNAPVF +S Y V ENN P + ++A D D
Sbjct: 419 TVTATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVRASDPD 478
Query: 489 LGINGKVSYRIQDSPV-----AHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQP 543
LG NG+VSY I S + + V+I + +G V AQR+ ++E++ FE + A D G P
Sbjct: 479 LGPNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQARDQGSP 538
Query: 544 MLASSVSVWVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGT 603
L+++VS+ V + D NDNAP V+ P L GP G+
Sbjct: 539 ALSANVSLRVLVDDRNDNAPRVLYPAL----------------------------GPDGS 570
Query: 604 DTPPLATHSSRP-FLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTN 662
+ H++ P +L+T +VA DADSG N Y + +E LF L TG+ V
Sbjct: 571 ALFDMVPHAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGE----VRT 626
Query: 663 ASSLIGSE---WELEIVVEDQGSPPLQTRALLRVMFVTSVDH-LRDSARKP------GAL 712
A +L + L + V D G PPL A L ++F S+ L D +P L
Sbjct: 627 ARALGDRDAVRQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDITDRPDPSDLQAEL 686
Query: 713 SMSMLTVICLAVLLGIFGLILALFMSICRT 742
++ + L +L + +ILA+ + + R+
Sbjct: 687 QFYLVVALALISVLFLVAMILAIALRLRRS 716
>gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precursor
[Homo sapiens]
Length = 923
Score = 414 bits (1064), Expect = e-115
Identities = 264/750 (35%), Positives = 400/750 (53%), Gaps = 75/750 (10%)
Query: 17 YLFLLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLP---- 72
+LFLL ++Y++ EE+P G+V+G L+ +LG F V +LP
Sbjct: 18 FLFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLG-----------FSVQELPTRKL 66
Query: 73 ----QALPIQVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDI 128
+ V +E G L RLDRE++C + C + F+ +A L HV +++ DI
Sbjct: 67 RVSSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHVNVEIEDI 126
Query: 129 NDHQPRFPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGP 188
NDH P+F + EL+ISESA TR L A D D G NTL Y LSPS+HF+L
Sbjct: 127 NDHTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKS 186
Query: 189 DETKHAELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESS 248
D +K+ E+++ LDRE + L LTA D G PP S T+ + V V D+NDN+P F++
Sbjct: 187 DGSKYPEMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDV 246
Query: 249 LALEIQEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRR 308
+ + E+ PGT ++++TATD D+G N E+ F S+ + F +++ TG++ +
Sbjct: 247 YRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSE---ASQITQFDLNSNTGEITVLN 303
Query: 309 PLDYEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALP 368
LD+E+ Y + ++ARD G + A C V ++V+D NDN P V + S P+L+ E
Sbjct: 304 TLDFEEVKEYSIVLEARDGGG--MIAQCTVEVEVIDENDNAPE--VIFQSLPNLIMEDAE 359
Query: 369 KDSFIALVMADDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTL 428
+ IAL+ D DS HNG V C L ++ F++ ++ NTY L+T+A LDREQ P+Y +
Sbjct: 360 LGTHIALLKVRDKDSRHNGEVTCKLEGDVP-FKILTSSRNTYKLVTDAVLDREQNPEYNI 418
Query: 429 TLLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDAD 488
T+ A D+G PLS+ +++ I D+NDNAPVF +S Y V ENN P + ++A D D
Sbjct: 419 TVTATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVRASDPD 478
Query: 489 LGINGKVSYRIQDSPV-----AHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQP 543
LG NG+VSY I S + + V+I + +G V AQR+ ++E++ FE + A D G P
Sbjct: 479 LGPNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQARDQGSP 538
Query: 544 MLASSVSVWVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGT 603
L+++VS+ V + D NDNAP V+ P L GP G+
Sbjct: 539 ALSANVSLRVLVDDRNDNAPRVLYPAL----------------------------GPDGS 570
Query: 604 DTPPLATHSSRP-FLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTN 662
+ H++ P +L+T +VA DADSG N Y + +E LF L TG+ V
Sbjct: 571 ALFDMVPHAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGE----VRT 626
Query: 663 ASSLIGSE---WELEIVVEDQGSPPLQTRALLRVMFVTSVDH-LRDSARKP------GAL 712
A +L + L + V D G PPL A L ++F S+ L D +P L
Sbjct: 627 ARALGDRDAVRQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDITDRPDPSDLQAEL 686
Query: 713 SMSMLTVICLAVLLGIFGLILALFMSICRT 742
++ + L +L + +ILA+ + + R+
Sbjct: 687 QFYLVVALALISVLFLVAMILAIALRLRRS 716
>gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precursor
[Homo sapiens]
Length = 871
Score = 414 bits (1063), Expect = e-115
Identities = 266/721 (36%), Positives = 382/721 (52%), Gaps = 45/721 (6%)
Query: 32 VKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQVDSEEGLLSTGRR 91
++Y V EE GT +G ++Q+ + A QV +VD + G L
Sbjct: 31 IRYPVPEESQEGTFVGNVAQDFLLDTDSLSA-RRLQVAGEVNQRHFRVDLDSGALLIKNP 89
Query: 92 LDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQELEISESASLR 151
+DRE LC C+V + + G L + E++++D+NDH PRFP+ + +LEI E+A
Sbjct: 90 IDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAPPG 149
Query: 152 TRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVVKELDREIHSFFD 211
R PL++A D D G N++ +Y LS +EHFALDV D + EL++ K LDRE S +
Sbjct: 150 QRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSDYR 209
Query: 212 LVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAPGTLLIKLTATDP 271
LVLTA D GNPP+SGT+ ++V+VLD NDN+PAF +SS + + E A G +LI+L A+DP
Sbjct: 210 LVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASDP 269
Query: 272 DQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYEVDVQARDLGPNP 331
D GP+G V F+ S H P V + FS+ TG++ L PLD+E YE DV+ARD G
Sbjct: 270 DLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSPA 329
Query: 332 IPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMADDLDSGHNGLVHC 391
+ HC + + +LDVNDN P I VT S+ + E+ + +AL+ D DSG NG V
Sbjct: 330 MEQHCSLRVDLLDVNDNAPYITVT--SELGTLPESAEPGTVVALISVQDPDSGSNGDVSL 387
Query: 392 WLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQPLSAKKQLSIQIS 451
+ L F LK N + L+T LDRE Y + + A D G PLS + + + IS
Sbjct: 388 RIPDHLP-FALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNIS 446
Query: 452 DINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSY-----RIQDSPVAH 506
D+NDN P F + +EV ENN P L ++ A D D G+N +SY R +D +
Sbjct: 447 DVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASS 506
Query: 507 LVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVSLLDANDNAPEVV 566
++++ TG V A RS +YE+ +F+V A D G P L+S+V+V + +LD NDNAP V+
Sbjct: 507 FISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVL 566
Query: 567 QPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSSRPFLLTTIVARDA 626
+P G L P P +G A H L+T + A D
Sbjct: 567 RPRARPGS--------------LCPQALPPSVG---------AGH-----LITKVTAVDL 598
Query: 627 DSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSEWELEIVVEDQGSPPLQ 686
DSG N Y + + LF ++ + G++ V + L +L IVV+D GSPPL
Sbjct: 599 DSGYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADL--PPQKLVIVVKDSGSPPLS 656
Query: 687 TRALLRVMFVTS----VDHLRD-SARKPGALSMSM-LTVICLAVLLGIFGLILALFMSIC 740
T L V V LR+ SA + G +++ L V +A+ FG +AL
Sbjct: 657 TSVTLLVSLEEDTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCL 716
Query: 741 R 741
R
Sbjct: 717 R 717
>gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precursor
[Homo sapiens]
Length = 938
Score = 414 bits (1063), Expect = e-115
Identities = 266/721 (36%), Positives = 382/721 (52%), Gaps = 45/721 (6%)
Query: 32 VKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQVDSEEGLLSTGRR 91
++Y V EE GT +G ++Q+ + A QV +VD + G L
Sbjct: 31 IRYPVPEESQEGTFVGNVAQDFLLDTDSLSA-RRLQVAGEVNQRHFRVDLDSGALLIKNP 89
Query: 92 LDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQELEISESASLR 151
+DRE LC C+V + + G L + E++++D+NDH PRFP+ + +LEI E+A
Sbjct: 90 IDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAPPG 149
Query: 152 TRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVVKELDREIHSFFD 211
R PL++A D D G N++ +Y LS +EHFALDV D + EL++ K LDRE S +
Sbjct: 150 QRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSDYR 209
Query: 212 LVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAPGTLLIKLTATDP 271
LVLTA D GNPP+SGT+ ++V+VLD NDN+PAF +SS + + E A G +LI+L A+DP
Sbjct: 210 LVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASDP 269
Query: 272 DQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYEVDVQARDLGPNP 331
D GP+G V F+ S H P V + FS+ TG++ L PLD+E YE DV+ARD G
Sbjct: 270 DLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSPA 329
Query: 332 IPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMADDLDSGHNGLVHC 391
+ HC + + +LDVNDN P I VT S+ + E+ + +AL+ D DSG NG V
Sbjct: 330 MEQHCSLRVDLLDVNDNAPYITVT--SELGTLPESAEPGTVVALISVQDPDSGSNGDVSL 387
Query: 392 WLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQPLSAKKQLSIQIS 451
+ L F LK N + L+T LDRE Y + + A D G PLS + + + IS
Sbjct: 388 RIPDHLP-FALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNIS 446
Query: 452 DINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSY-----RIQDSPVAH 506
D+NDN P F + +EV ENN P L ++ A D D G+N +SY R +D +
Sbjct: 447 DVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASS 506
Query: 507 LVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVSLLDANDNAPEVV 566
++++ TG V A RS +YE+ +F+V A D G P L+S+V+V + +LD NDNAP V+
Sbjct: 507 FISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVL 566
Query: 567 QPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSSRPFLLTTIVARDA 626
+P G L P P +G A H L+T + A D
Sbjct: 567 RPRARPGS--------------LCPQALPPSVG---------AGH-----LITKVTAVDL 598
Query: 627 DSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSEWELEIVVEDQGSPPLQ 686
DSG N Y + + LF ++ + G++ V + L +L IVV+D GSPPL
Sbjct: 599 DSGYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADL--PPQKLVIVVKDSGSPPLS 656
Query: 687 TRALLRVMFVTS----VDHLRD-SARKPGALSMSM-LTVICLAVLLGIFGLILALFMSIC 740
T L V V LR+ SA + G +++ L V +A+ FG +AL
Sbjct: 657 TSVTLLVSLEEDTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCL 716
Query: 741 R 741
R
Sbjct: 717 R 717
>gi|11056030 protocadherin gamma subfamily A, 2 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 414 bits (1063), Expect = e-115
Identities = 257/725 (35%), Positives = 393/725 (54%), Gaps = 52/725 (7%)
Query: 19 FLLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQ 78
FLL E ++Y V EE+ G+ +G ++++LG E A +++ ++
Sbjct: 18 FLLATLWEARAGQIRYSVREEIDRGSFVGNIAKDLGLEPLAL-AEQGVRIVSRGRSQLFA 76
Query: 79 VDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKG 138
++ G L T R+DRE+LC Q PCL++F++L L + VE+++ DIND+ PRF
Sbjct: 77 LNPRSGSLVTANRIDREELCAQSAPCLLNFNILLEDKLTIYSVEVEITDINDNAPRFGVE 136
Query: 139 EQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIV 198
E EL+ISE+ + RIPL A D D G N L Y L+P++HF+LDV G D K+ EL++
Sbjct: 137 ELELKISETTTPGFRIPLKNAHDADVGENALQKYALNPNDHFSLDVRRGADGNKYPELVL 196
Query: 199 VKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAA 258
+ LDRE + LVL A D G+P SGTS + V VLD+NDN+P F + + I E+
Sbjct: 197 ERSLDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYRISIPENTL 256
Query: 259 PGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAY 318
GT ++ +TATD D+G +V +FL K P E + F + + +G++ + + LDYE +
Sbjct: 257 VGTRILTVTATDADEGYYAQVVYFLEK-SPGETSEVFELKSTSGELTIIKDLDYEDATFH 315
Query: 319 EVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMA 378
E+D++A+D GP + KV++ VLDVNDN P ++T S S VSE + I L
Sbjct: 316 EIDIEAQD-GPG-LLTRAKVIVTVLDVNDNAPEFYMT--SATSSVSEDSLPGTIIGLFNV 371
Query: 379 DDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQ 438
D DSG N C L ++L F+L+++ N Y L+T LDREQ+ Y +TL A+D G
Sbjct: 372 HDRDSGQNAFTTCSLPEDL-PFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGGNP 430
Query: 439 PLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSY- 497
LS + +Q++DINDNAP F ++ Y ENN + ++ AHD D N V+Y
Sbjct: 431 SLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDSNDNAHVTYS 490
Query: 498 ----RIQDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWV 553
+Q +P++ ++I+S+TG + A RS +YE++ + VIA DSG P L+S+VS+ +
Sbjct: 491 FAEDTVQGAPLSSYISINSDTGVLYALRSFDYEQLRDLQVWVIARDSGNPPLSSNVSLSL 550
Query: 554 SLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSS 613
+LD NDNAPE++ P + STG L P G
Sbjct: 551 FVLDQNDNAPEILYPAFP---------TDGSTGVELAPRSAEPG---------------- 585
Query: 614 RPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSE--- 670
+L+T +VA D DSG N Y + +E LF + HTG+ V A +L+ +
Sbjct: 586 --YLVTKVVAVDRDSGQNAWLSYHLLKASEPGLFSVGLHTGE----VRTARALLDRDALK 639
Query: 671 WELEIVVEDQGSPPLQTRALLRVMFVTSV-DHLRD-SARKPGAL----SMSMLTVICLAV 724
L + ++D G PPL L V + D L D + +P A+ +++ V+ +A
Sbjct: 640 QSLVVAIQDHGQPPLSATVTLTVAVADRIPDILADLGSLEPSAIPNDSDLTLYLVVAVAA 699
Query: 725 LLGIF 729
+ +F
Sbjct: 700 VSCVF 704
>gi|14196462 protocadherin gamma subfamily A, 2 isoform 2 precursor
[Homo sapiens]
Length = 823
Score = 414 bits (1063), Expect = e-115
Identities = 257/725 (35%), Positives = 393/725 (54%), Gaps = 52/725 (7%)
Query: 19 FLLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQ 78
FLL E ++Y V EE+ G+ +G ++++LG E A +++ ++
Sbjct: 18 FLLATLWEARAGQIRYSVREEIDRGSFVGNIAKDLGLEPLAL-AEQGVRIVSRGRSQLFA 76
Query: 79 VDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKG 138
++ G L T R+DRE+LC Q PCL++F++L L + VE+++ DIND+ PRF
Sbjct: 77 LNPRSGSLVTANRIDREELCAQSAPCLLNFNILLEDKLTIYSVEVEITDINDNAPRFGVE 136
Query: 139 EQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIV 198
E EL+ISE+ + RIPL A D D G N L Y L+P++HF+LDV G D K+ EL++
Sbjct: 137 ELELKISETTTPGFRIPLKNAHDADVGENALQKYALNPNDHFSLDVRRGADGNKYPELVL 196
Query: 199 VKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAA 258
+ LDRE + LVL A D G+P SGTS + V VLD+NDN+P F + + I E+
Sbjct: 197 ERSLDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYRISIPENTL 256
Query: 259 PGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAY 318
GT ++ +TATD D+G +V +FL K P E + F + + +G++ + + LDYE +
Sbjct: 257 VGTRILTVTATDADEGYYAQVVYFLEK-SPGETSEVFELKSTSGELTIIKDLDYEDATFH 315
Query: 319 EVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMA 378
E+D++A+D GP + KV++ VLDVNDN P ++T S S VSE + I L
Sbjct: 316 EIDIEAQD-GPG-LLTRAKVIVTVLDVNDNAPEFYMT--SATSSVSEDSLPGTIIGLFNV 371
Query: 379 DDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQ 438
D DSG N C L ++L F+L+++ N Y L+T LDREQ+ Y +TL A+D G
Sbjct: 372 HDRDSGQNAFTTCSLPEDL-PFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGGNP 430
Query: 439 PLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSY- 497
LS + +Q++DINDNAP F ++ Y ENN + ++ AHD D N V+Y
Sbjct: 431 SLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDSNDNAHVTYS 490
Query: 498 ----RIQDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWV 553
+Q +P++ ++I+S+TG + A RS +YE++ + VIA DSG P L+S+VS+ +
Sbjct: 491 FAEDTVQGAPLSSYISINSDTGVLYALRSFDYEQLRDLQVWVIARDSGNPPLSSNVSLSL 550
Query: 554 SLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSS 613
+LD NDNAPE++ P + STG L P G
Sbjct: 551 FVLDQNDNAPEILYPAFP---------TDGSTGVELAPRSAEPG---------------- 585
Query: 614 RPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSE--- 670
+L+T +VA D DSG N Y + +E LF + HTG+ V A +L+ +
Sbjct: 586 --YLVTKVVAVDRDSGQNAWLSYHLLKASEPGLFSVGLHTGE----VRTARALLDRDALK 639
Query: 671 WELEIVVEDQGSPPLQTRALLRVMFVTSV-DHLRD-SARKPGAL----SMSMLTVICLAV 724
L + ++D G PPL L V + D L D + +P A+ +++ V+ +A
Sbjct: 640 QSLVVAIQDHGQPPLSATVTLTVAVADRIPDILADLGSLEPSAIPNDSDLTLYLVVAVAA 699
Query: 725 LLGIF 729
+ +F
Sbjct: 700 VSCVF 704
>gi|11128035 protocadherin gamma subfamily B, 2 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 412 bits (1058), Expect = e-114
Identities = 259/752 (34%), Positives = 404/752 (53%), Gaps = 63/752 (8%)
Query: 19 FLLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQ 78
FLL + ++Y + EE+ +V+G L+++LG R A ++ +
Sbjct: 20 FLLSLFPGALPVQIRYSIPEELAKNSVVGNLAKDLGLSVRDLPAR---KLRVSAEKEYFT 76
Query: 79 VDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKG 138
V+ E G L R+DREQ+C + C++ FD +A L + ++ + V DIND+ P F +
Sbjct: 77 VNPESGDLLVSDRIDREQICGKQPLCVLDFDTVAENPLNIFYIAVIVQDINDNTPLFKQT 136
Query: 139 EQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIV 198
+ L+I ES T PLD ALD D GPN+L Y L+ +E+F L PD K+ ELI+
Sbjct: 137 KINLKIGESTKPGTTFPLDPALDSDVGPNSLQRYHLNDNEYFDLAEKQTPDGRKYPELIL 196
Query: 199 VKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAA 258
LDRE HS LVLTA D G+PP+SGT+ +++ V D+NDN P F++ + ++ED
Sbjct: 197 KHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRIKVTDANDNPPVFSQDVYRVTLREDVP 256
Query: 259 PGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAY 318
PG ++++TATD D+G N E+ + ++ +V F+++ KTG++ + LD+E +Y
Sbjct: 257 PGFFVLQVTATDRDEGINAEITYSFH-NVDEQVKHFFNLNEKTGEITTKDDLDFEIASSY 315
Query: 319 EVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMA 378
+ ++A+D P + AHC + +++LD ND P + VT S P + E P + IAL+
Sbjct: 316 TLSIEAKD--PGDLAAHCSIQVEILDDNDCAPEVIVTSVSTP--LPEDSPPGTVIALIKT 371
Query: 379 DDLDSGHNGLVHCWLSQELGH--FRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQG 436
D DSG NG V+C Q LG+ F LK ++ N Y L+T+ LDRE+ P+Y LT+ A D G
Sbjct: 372 RDRDSGENGEVYC---QVLGNAKFILKSSSKNYYKLVTDGALDREEIPEYNLTITATDGG 428
Query: 437 LQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVS 496
PLS+ +++ ISD+NDNAPVF+++ Y V ENN P + I A D DLG +G+VS
Sbjct: 429 KPPLSSSIIVTLHISDVNDNAPVFQQTSYMVHVAENNPPGASIAQISASDPDLGPSGQVS 488
Query: 497 YRIQDSP-----VAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSV 551
Y I S + V++ + +G V AQR+ ++E++ FE + A D G P L+++VS+
Sbjct: 489 YSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSL 548
Query: 552 WVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATH 611
V + D NDNAP V+ P L GP G+ +
Sbjct: 549 RVLVGDLNDNAPRVLYPAL----------------------------GPDGSALFDMVPR 580
Query: 612 SSRP-FLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSL---I 667
++ P +L+T +VA DADSG N Y + +E LF L TG+ V A +L
Sbjct: 581 AAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGE----VRTARALGDRD 636
Query: 668 GSEWELEIVVEDQGSPPLQTRALLRVMFVTSVDHL-------RDSARKPGALSMSMLTVI 720
+ L + V D G PPL A L ++F S+ + R+ + L ++ +
Sbjct: 637 AARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLPDLSDRREPSDPQAKLQFYLVVAL 696
Query: 721 CLAVLLGIFGLILALFMSICRTEKKDNRAYNC 752
L +L +ILA+ + + + + D A++C
Sbjct: 697 ALISVLFFLAVILAISLRLRLSSRSD--AWDC 726
>gi|14270493 protocadherin gamma subfamily B, 2 isoform 2 precursor
[Homo sapiens]
Length = 811
Score = 412 bits (1058), Expect = e-114
Identities = 259/752 (34%), Positives = 404/752 (53%), Gaps = 63/752 (8%)
Query: 19 FLLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQ 78
FLL + ++Y + EE+ +V+G L+++LG R A ++ +
Sbjct: 20 FLLSLFPGALPVQIRYSIPEELAKNSVVGNLAKDLGLSVRDLPAR---KLRVSAEKEYFT 76
Query: 79 VDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKG 138
V+ E G L R+DREQ+C + C++ FD +A L + ++ + V DIND+ P F +
Sbjct: 77 VNPESGDLLVSDRIDREQICGKQPLCVLDFDTVAENPLNIFYIAVIVQDINDNTPLFKQT 136
Query: 139 EQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIV 198
+ L+I ES T PLD ALD D GPN+L Y L+ +E+F L PD K+ ELI+
Sbjct: 137 KINLKIGESTKPGTTFPLDPALDSDVGPNSLQRYHLNDNEYFDLAEKQTPDGRKYPELIL 196
Query: 199 VKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAA 258
LDRE HS LVLTA D G+PP+SGT+ +++ V D+NDN P F++ + ++ED
Sbjct: 197 KHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRIKVTDANDNPPVFSQDVYRVTLREDVP 256
Query: 259 PGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAY 318
PG ++++TATD D+G N E+ + ++ +V F+++ KTG++ + LD+E +Y
Sbjct: 257 PGFFVLQVTATDRDEGINAEITYSFH-NVDEQVKHFFNLNEKTGEITTKDDLDFEIASSY 315
Query: 319 EVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMA 378
+ ++A+D P + AHC + +++LD ND P + VT S P + E P + IAL+
Sbjct: 316 TLSIEAKD--PGDLAAHCSIQVEILDDNDCAPEVIVTSVSTP--LPEDSPPGTVIALIKT 371
Query: 379 DDLDSGHNGLVHCWLSQELGH--FRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQG 436
D DSG NG V+C Q LG+ F LK ++ N Y L+T+ LDRE+ P+Y LT+ A D G
Sbjct: 372 RDRDSGENGEVYC---QVLGNAKFILKSSSKNYYKLVTDGALDREEIPEYNLTITATDGG 428
Query: 437 LQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVS 496
PLS+ +++ ISD+NDNAPVF+++ Y V ENN P + I A D DLG +G+VS
Sbjct: 429 KPPLSSSIIVTLHISDVNDNAPVFQQTSYMVHVAENNPPGASIAQISASDPDLGPSGQVS 488
Query: 497 YRIQDSP-----VAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSV 551
Y I S + V++ + +G V AQR+ ++E++ FE + A D G P L+++VS+
Sbjct: 489 YSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSL 548
Query: 552 WVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATH 611
V + D NDNAP V+ P L GP G+ +
Sbjct: 549 RVLVGDLNDNAPRVLYPAL----------------------------GPDGSALFDMVPR 580
Query: 612 SSRP-FLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSL---I 667
++ P +L+T +VA DADSG N Y + +E LF L TG+ V A +L
Sbjct: 581 AAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGE----VRTARALGDRD 636
Query: 668 GSEWELEIVVEDQGSPPLQTRALLRVMFVTSVDHL-------RDSARKPGALSMSMLTVI 720
+ L + V D G PPL A L ++F S+ + R+ + L ++ +
Sbjct: 637 AARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLPDLSDRREPSDPQAKLQFYLVVAL 696
Query: 721 CLAVLLGIFGLILALFMSICRTEKKDNRAYNC 752
L +L +ILA+ + + + + D A++C
Sbjct: 697 ALISVLFFLAVILAISLRLRLSSRSD--AWDC 726
>gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 411 bits (1057), Expect = e-114
Identities = 251/734 (34%), Positives = 403/734 (54%), Gaps = 52/734 (7%)
Query: 20 LLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQV 79
LLG E+ + Y V EE G+V+G ++++LG R A +++ + +
Sbjct: 19 LLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPREL-AERGVRIVSRGRTQLFAL 77
Query: 80 DSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGE 139
+ G L T R+DRE+LC + C+ + ++L + ++ VE++++D+ND+ P F +
Sbjct: 78 NPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQ 137
Query: 140 QELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVV 199
+E++++E+ + R PL A DPD G N+L Y L+ + +F+LDV G D K+ EL++
Sbjct: 138 REIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLE 197
Query: 200 KELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAP 259
+ LDRE + LVLTA+D G+P +SGT+ + + ++D+NDN+P F + + ++E+
Sbjct: 198 RALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSVRENVPV 257
Query: 260 GTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYE 319
GT L+ + ATDPD+G NG+V + K + ++ F +++ +G + + LDYE + Y+
Sbjct: 258 GTRLLTVKATDPDEGANGDVTYSFRK-VRDKISQLFQLNSLSGDITILGGLDYEDSGFYD 316
Query: 320 VDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMAD 379
+DV+A D GP + A KVL+ VLD NDN P + VT S S V E+ + IAL
Sbjct: 317 IDVEAHD-GPG-LRARSKVLVTVLDENDNAPEVTVT--SLTSSVQESSSPGTVIALFNVH 372
Query: 380 DLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQP 439
D DSG NGLV C + L F L++T GN Y LLT+ TLDRE+ +Y +T+ A DQG P
Sbjct: 373 DSDSGGNGLVTCSIPDNL-PFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQGTPP 431
Query: 440 LSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSYRI 499
LS + +S+Q+ DINDN P F + Y ENN ++++ A D D G N +++Y +
Sbjct: 432 LSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARITYSL 491
Query: 500 -----QDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVS 554
Q +P++ V+I+SNTG + A S +YE+ + + A DSG P L+S+VS+ +
Sbjct: 492 AEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSLSLF 551
Query: 555 LLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSSR 614
+LD NDN PE++ P + STG L P +G
Sbjct: 552 VLDQNDNVPEILYPTFP---------TDGSTGVELAPRSADSG----------------- 585
Query: 615 PFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSE---W 671
+L+T +VA D DSG N YS+ +E LF + HTG+ V A +L+ +
Sbjct: 586 -YLVTKVVAVDRDSGQNAWLSYSLLKSSEPGLFAVGLHTGE----VRTARALLDRDALKQ 640
Query: 672 ELEIVVEDQGSPPLQTRALLRVMFVTSV-DHLRD-SARKPGA----LSMSMLTVICLAVL 725
L +VV+D G PPL L V S+ D L D + KP A +++ V+ +A +
Sbjct: 641 RLVVVVQDHGQPPLSATVTLTVAVADSIPDVLADLGSLKPSADPDDSGLTLYLVVAVAAV 700
Query: 726 LGIFGLILALFMSI 739
+F + + +++
Sbjct: 701 SCVFLAFVTVLLAL 714
>gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 411 bits (1057), Expect = e-114
Identities = 251/734 (34%), Positives = 403/734 (54%), Gaps = 52/734 (7%)
Query: 20 LLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQV 79
LLG E+ + Y V EE G+V+G ++++LG R A +++ + +
Sbjct: 19 LLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPREL-AERGVRIVSRGRTQLFAL 77
Query: 80 DSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGE 139
+ G L T R+DRE+LC + C+ + ++L + ++ VE++++D+ND+ P F +
Sbjct: 78 NPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQ 137
Query: 140 QELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVV 199
+E++++E+ + R PL A DPD G N+L Y L+ + +F+LDV G D K+ EL++
Sbjct: 138 REIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLE 197
Query: 200 KELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAP 259
+ LDRE + LVLTA+D G+P +SGT+ + + ++D+NDN+P F + + ++E+
Sbjct: 198 RALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSVRENVPV 257
Query: 260 GTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYE 319
GT L+ + ATDPD+G NG+V + K + ++ F +++ +G + + LDYE + Y+
Sbjct: 258 GTRLLTVKATDPDEGANGDVTYSFRK-VRDKISQLFQLNSLSGDITILGGLDYEDSGFYD 316
Query: 320 VDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMAD 379
+DV+A D GP + A KVL+ VLD NDN P + VT S S V E+ + IAL
Sbjct: 317 IDVEAHD-GPG-LRARSKVLVTVLDENDNAPEVTVT--SLTSSVQESSSPGTVIALFNVH 372
Query: 380 DLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQP 439
D DSG NGLV C + L F L++T GN Y LLT+ TLDRE+ +Y +T+ A DQG P
Sbjct: 373 DSDSGGNGLVTCSIPDNL-PFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQGTPP 431
Query: 440 LSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSYRI 499
LS + +S+Q+ DINDN P F + Y ENN ++++ A D D G N +++Y +
Sbjct: 432 LSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARITYSL 491
Query: 500 -----QDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVS 554
Q +P++ V+I+SNTG + A S +YE+ + + A DSG P L+S+VS+ +
Sbjct: 492 AEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSLSLF 551
Query: 555 LLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSSR 614
+LD NDN PE++ P + STG L P +G
Sbjct: 552 VLDQNDNVPEILYPTFP---------TDGSTGVELAPRSADSG----------------- 585
Query: 615 PFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSE---W 671
+L+T +VA D DSG N YS+ +E LF + HTG+ V A +L+ +
Sbjct: 586 -YLVTKVVAVDRDSGQNAWLSYSLLKSSEPGLFAVGLHTGE----VRTARALLDRDALKQ 640
Query: 672 ELEIVVEDQGSPPLQTRALLRVMFVTSV-DHLRD-SARKPGA----LSMSMLTVICLAVL 725
L +VV+D G PPL L V S+ D L D + KP A +++ V+ +A +
Sbjct: 641 RLVVVVQDHGQPPLSATVTLTVAVADSIPDVLADLGSLKPSADPDDSGLTLYLVVAVAAV 700
Query: 726 LGIFGLILALFMSI 739
+F + + +++
Sbjct: 701 SCVFLAFVTVLLAL 714
>gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 409 bits (1052), Expect = e-114
Identities = 250/734 (34%), Positives = 398/734 (54%), Gaps = 52/734 (7%)
Query: 20 LLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQV 79
LLG E+ ++Y V EE G+ +G +S++LG + R+ A +++ + +
Sbjct: 19 LLGTLWEIGRGQIRYSVPEETDKGSFVGNISKDLGLDPRKL-AKHGVRIVSRGRTQLFAL 77
Query: 80 DSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGE 139
+ G L T R+DRE+LC Q CL++ + L L VEI+++DIND+ P+F +
Sbjct: 78 NPRSGSLITAGRIDREELCAQSPRCLININTLVEDKGKLFGVEIEIIDINDNNPKFQVED 137
Query: 140 QELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVV 199
E++I+E A R PL A+DPD G N+L +Y LSP+ HF+LDV G + + EL++
Sbjct: 138 LEVKINEIAVPGARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDVQTGDNGAINPELVLE 197
Query: 200 KELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAP 259
+ LDRE + LVLTA D G PP+S T + V VLD+NDN+P F +++ E+ P
Sbjct: 198 RALDREEEAAHHLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVKVLENMPP 257
Query: 260 GTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYE 319
GT L+ +TA+DPD+G NG+V + K + + F ++ TG++ + + LDYE+ YE
Sbjct: 258 GTRLLTVTASDPDEGINGKVAYKFRK-INEKQTPLFQLNENTGEISIAKSLDYEECSFYE 316
Query: 320 VDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMAD 379
+++QA D+G + K+LI V DVNDN P + +T P ++ +LP + IA +
Sbjct: 317 MEIQAEDVG--ALLGRTKLLISVEDVNDNRPEVIITSLFSP-VLENSLP-GTVIAFLSVH 372
Query: 380 DLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQP 439
D DSG NG V C+ L F+L+++ GN Y L+T LDRE Y +T++A D G P
Sbjct: 373 DQDSGKNGQVVCYTRDNL-PFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDLGTPP 431
Query: 440 LSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSYRI 499
LS + Q+++ ++DINDN P F + Y ENNL + ++ AHD D N +V+Y +
Sbjct: 432 LSTETQIALHVADINDNPPTFPHASYSAYILENNLRGASIFSLTAHDPDSQENAQVTYSV 491
Query: 500 -----QDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVS 554
Q +P++ ++I+S+TG + A +S +YE++ + V A DSG P L+S++S+ +
Sbjct: 492 TEDTLQGAPLSSYISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGDPPLSSNMSLSLF 551
Query: 555 LLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSSR 614
+LD NDNAPE++ P L + STG L P + R
Sbjct: 552 VLDQNDNAPEILYPALP---------TDGSTGVELAP------------------RSAER 584
Query: 615 PFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSE---W 671
+L+T +VA D DSG N Y + +E LF + HTG+ V A +L+ +
Sbjct: 585 GYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGE----VRTARALLDRDALKQ 640
Query: 672 ELEIVVEDQGSPPLQTRALLRVMFVTSVDHLRDS------ARKPGALSMSMLTVICLAVL 725
L + V+D G PPL L V S+ + + P S+++ V+ +A +
Sbjct: 641 SLVVAVQDHGQPPLSATVTLTVAVADSIPEVLTELGSLKPSVDPNDSSLTLYLVVAVAAI 700
Query: 726 LGIFGLILALFMSI 739
+F +A+ + +
Sbjct: 701 SCVFLAFVAVLLGL 714
>gi|7662056 protocadherin gamma subfamily A, 8 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 409 bits (1052), Expect = e-114
Identities = 250/734 (34%), Positives = 398/734 (54%), Gaps = 52/734 (7%)
Query: 20 LLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQV 79
LLG E+ ++Y V EE G+ +G +S++LG + R+ A +++ + +
Sbjct: 19 LLGTLWEIGRGQIRYSVPEETDKGSFVGNISKDLGLDPRKL-AKHGVRIVSRGRTQLFAL 77
Query: 80 DSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGE 139
+ G L T R+DRE+LC Q CL++ + L L VEI+++DIND+ P+F +
Sbjct: 78 NPRSGSLITAGRIDREELCAQSPRCLININTLVEDKGKLFGVEIEIIDINDNNPKFQVED 137
Query: 140 QELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVV 199
E++I+E A R PL A+DPD G N+L +Y LSP+ HF+LDV G + + EL++
Sbjct: 138 LEVKINEIAVPGARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDVQTGDNGAINPELVLE 197
Query: 200 KELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAP 259
+ LDRE + LVLTA D G PP+S T + V VLD+NDN+P F +++ E+ P
Sbjct: 198 RALDREEEAAHHLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVKVLENMPP 257
Query: 260 GTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYE 319
GT L+ +TA+DPD+G NG+V + K + + F ++ TG++ + + LDYE+ YE
Sbjct: 258 GTRLLTVTASDPDEGINGKVAYKFRK-INEKQTPLFQLNENTGEISIAKSLDYEECSFYE 316
Query: 320 VDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMAD 379
+++QA D+G + K+LI V DVNDN P + +T P ++ +LP + IA +
Sbjct: 317 MEIQAEDVG--ALLGRTKLLISVEDVNDNRPEVIITSLFSP-VLENSLP-GTVIAFLSVH 372
Query: 380 DLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQP 439
D DSG NG V C+ L F+L+++ GN Y L+T LDRE Y +T++A D G P
Sbjct: 373 DQDSGKNGQVVCYTRDNL-PFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDLGTPP 431
Query: 440 LSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSYRI 499
LS + Q+++ ++DINDN P F + Y ENNL + ++ AHD D N +V+Y +
Sbjct: 432 LSTETQIALHVADINDNPPTFPHASYSAYILENNLRGASIFSLTAHDPDSQENAQVTYSV 491
Query: 500 -----QDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVS 554
Q +P++ ++I+S+TG + A +S +YE++ + V A DSG P L+S++S+ +
Sbjct: 492 TEDTLQGAPLSSYISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGDPPLSSNMSLSLF 551
Query: 555 LLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSSR 614
+LD NDNAPE++ P L + STG L P + R
Sbjct: 552 VLDQNDNAPEILYPALP---------TDGSTGVELAP------------------RSAER 584
Query: 615 PFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSE---W 671
+L+T +VA D DSG N Y + +E LF + HTG+ V A +L+ +
Sbjct: 585 GYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGE----VRTARALLDRDALKQ 640
Query: 672 ELEIVVEDQGSPPLQTRALLRVMFVTSVDHLRDS------ARKPGALSMSMLTVICLAVL 725
L + V+D G PPL L V S+ + + P S+++ V+ +A +
Sbjct: 641 SLVVAVQDHGQPPLSATVTLTVAVADSIPEVLTELGSLKPSVDPNDSSLTLYLVVAVAAI 700
Query: 726 LGIFGLILALFMSI 739
+F +A+ + +
Sbjct: 701 SCVFLAFVAVLLGL 714
>gi|14196471 protocadherin gamma subfamily A, 5 isoform 2 precursor
[Homo sapiens]
Length = 813
Score = 409 bits (1051), Expect = e-114
Identities = 250/724 (34%), Positives = 402/724 (55%), Gaps = 52/724 (7%)
Query: 20 LLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQV 79
LLG E + ++Y + EE+ G+ +G ++++LG E + A +++ + +
Sbjct: 19 LLGTLCEPGSGQIRYSMPEELDKGSFVGNIAKDLGLEPQEL-AERGVRIVSRGRTQLFAL 77
Query: 80 DSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGE 139
+ G L T R+DRE+LC Q C+V+F++L + + VE++++DIND+ PRF E
Sbjct: 78 NPRSGSLVTAGRIDREELCAQSPLCVVNFNILVENKMKIYGVEVEIIDINDNFPRFRDEE 137
Query: 140 QELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVV 199
+++++E+A+ TR+ L A D D G N+L +Y LS + HF+LDV+ G D K+ EL++
Sbjct: 138 LKVKVNENAAAGTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVSGTDGQKYPELVLE 197
Query: 200 KELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAP 259
+ LDRE + DL+LTA D G+P SGT+ ++V VLD+NDN+P F S ++ + E+
Sbjct: 198 QPLDREKETVHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYSVSVPENIPV 257
Query: 260 GTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYE 319
GT L+ LTATDPD+G NG++ + ++ ++ +TF +D+ G++ + LDYE++ Y
Sbjct: 258 GTRLLMLTATDPDEGINGKLTYSF-RNEEEKISETFQLDSNLGEISTLQSLDYEESRFYL 316
Query: 320 VDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMAD 379
++V A+D G + A KV++ V DVNDN P + +T S S +SE + IAL
Sbjct: 317 MEVVAQDGG--ALVASAKVVVTVQDVNDNAPEVILT--SLTSSISEDCLPGTVIALFSVH 372
Query: 380 DLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQP 439
D DSG NG + C + + L F+L+++ N Y LLT LDRE+ Y +TL D G P
Sbjct: 373 DGDSGENGEIACSIPRNL-PFKLEKSVDNYYHLLTTRDLDREETSDYNITLTVMDHGTPP 431
Query: 440 LSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSYRI 499
LS + + ++++D+NDN P F ++ Y S ENN + + ++ AHD D G N +V+Y +
Sbjct: 432 LSTESHIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIFSVTAHDPDSGDNARVTYSL 491
Query: 500 -----QDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVS 554
Q +P++ V+I+S+TG + A RS +YE++ + V A DSG P L+S+VS+ +
Sbjct: 492 AEDTFQGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLSSNVSLSLF 551
Query: 555 LLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSSR 614
+LD NDN PE++ P L + STG L P G
Sbjct: 552 VLDQNDNTPEILYPALP---------TDGSTGVELAPRSAEPG----------------- 585
Query: 615 PFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSE---W 671
+L+T +VA D DSG N Y + +E LF + HTG+ V A +L+ +
Sbjct: 586 -YLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGLHTGE----VRTARALLDRDALKQ 640
Query: 672 ELEIVVEDQGSPPLQTRALLRVMFVTSV-DHLRD-----SARKPGALSMSMLTVICLAVL 725
L + VED G PPL + V + D L D + P L +++ V+ +A +
Sbjct: 641 SLVVAVEDHGQPPLSATFTVTVAVADRIPDILADLGSIKTPIDPEDLDLTLYLVVAVAAV 700
Query: 726 LGIF 729
+F
Sbjct: 701 SCVF 704
>gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 409 bits (1051), Expect = e-114
Identities = 250/724 (34%), Positives = 402/724 (55%), Gaps = 52/724 (7%)
Query: 20 LLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQV 79
LLG E + ++Y + EE+ G+ +G ++++LG E + A +++ + +
Sbjct: 19 LLGTLCEPGSGQIRYSMPEELDKGSFVGNIAKDLGLEPQEL-AERGVRIVSRGRTQLFAL 77
Query: 80 DSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGE 139
+ G L T R+DRE+LC Q C+V+F++L + + VE++++DIND+ PRF E
Sbjct: 78 NPRSGSLVTAGRIDREELCAQSPLCVVNFNILVENKMKIYGVEVEIIDINDNFPRFRDEE 137
Query: 140 QELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVV 199
+++++E+A+ TR+ L A D D G N+L +Y LS + HF+LDV+ G D K+ EL++
Sbjct: 138 LKVKVNENAAAGTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVSGTDGQKYPELVLE 197
Query: 200 KELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAP 259
+ LDRE + DL+LTA D G+P SGT+ ++V VLD+NDN+P F S ++ + E+
Sbjct: 198 QPLDREKETVHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYSVSVPENIPV 257
Query: 260 GTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYE 319
GT L+ LTATDPD+G NG++ + ++ ++ +TF +D+ G++ + LDYE++ Y
Sbjct: 258 GTRLLMLTATDPDEGINGKLTYSF-RNEEEKISETFQLDSNLGEISTLQSLDYEESRFYL 316
Query: 320 VDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMAD 379
++V A+D G + A KV++ V DVNDN P + +T S S +SE + IAL
Sbjct: 317 MEVVAQDGG--ALVASAKVVVTVQDVNDNAPEVILT--SLTSSISEDCLPGTVIALFSVH 372
Query: 380 DLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQP 439
D DSG NG + C + + L F+L+++ N Y LLT LDRE+ Y +TL D G P
Sbjct: 373 DGDSGENGEIACSIPRNL-PFKLEKSVDNYYHLLTTRDLDREETSDYNITLTVMDHGTPP 431
Query: 440 LSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSYRI 499
LS + + ++++D+NDN P F ++ Y S ENN + + ++ AHD D G N +V+Y +
Sbjct: 432 LSTESHIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIFSVTAHDPDSGDNARVTYSL 491
Query: 500 -----QDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVS 554
Q +P++ V+I+S+TG + A RS +YE++ + V A DSG P L+S+VS+ +
Sbjct: 492 AEDTFQGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLSSNVSLSLF 551
Query: 555 LLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSSR 614
+LD NDN PE++ P L + STG L P G
Sbjct: 552 VLDQNDNTPEILYPALP---------TDGSTGVELAPRSAEPG----------------- 585
Query: 615 PFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSE---W 671
+L+T +VA D DSG N Y + +E LF + HTG+ V A +L+ +
Sbjct: 586 -YLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGLHTGE----VRTARALLDRDALKQ 640
Query: 672 ELEIVVEDQGSPPLQTRALLRVMFVTSV-DHLRD-----SARKPGALSMSMLTVICLAVL 725
L + VED G PPL + V + D L D + P L +++ V+ +A +
Sbjct: 641 SLVVAVEDHGQPPLSATFTVTVAVADRIPDILADLGSIKTPIDPEDLDLTLYLVVAVAAV 700
Query: 726 LGIF 729
+F
Sbjct: 701 SCVF 704
>gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precursor
[Homo sapiens]
Length = 863
Score = 407 bits (1047), Expect = e-113
Identities = 261/762 (34%), Positives = 386/762 (50%), Gaps = 53/762 (6%)
Query: 10 GLLGPG---GYLFLLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAF 66
GL+ G G L LLG + +T+ + Y++ EE G +G + LG + A F
Sbjct: 9 GLVSTGRVVGVLLLLGALNKASTV-IHYEIPEEREKGFAVGNVVANLGLDLGSLSA-RRF 66
Query: 67 QVLQLPQALPIQVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVL 126
+V+ +V+ E G + RLDRE+LC C V+ +++ L L VE+ +
Sbjct: 67 RVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQ 126
Query: 127 DINDHQPRFPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIV 186
DIND+ P FP E +LEISE+ + TR PL+ A DPD G N+L TY LS +E+FAL V
Sbjct: 127 DINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQT 186
Query: 187 GPDETKHAELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAE 246
D TK+AEL++ + LDRE LVLTA D G P S + + + VLD+NDN+P F +
Sbjct: 187 REDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQ 246
Query: 247 SSLALEIQEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVIL 306
S + EDA GT ++++ ATD D+GPNGE+ + H V F++D TG + +
Sbjct: 247 SLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTI 306
Query: 307 RRPLDYEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEA 366
+ LD+E +E+ +QA+D G NP AHCKVL++V+DVNDN P I VT P V E
Sbjct: 307 KGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP--VPED 364
Query: 367 LPKDSFIALVMADDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKY 426
P + IAL+ DLD+G NGLV C + L F L + N + L T+A LDRE P+Y
Sbjct: 365 APLGTVIALLSVTDLDAGENGLVTCEVPPGL-PFSLTSSLKNYFTLKTSADLDRETVPEY 423
Query: 427 TLTLLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHD 486
L++ A+D G LSA + +Q+SDINDN P +S Y+V ENNLP ++ + D
Sbjct: 424 NLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWD 483
Query: 487 ADLGINGKVSYRI-----QDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSG 541
D N ++S+ + + V I+ + G V++ L+YE+ FE D G
Sbjct: 484 PDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGG 543
Query: 542 QPMLASSVSVWVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPA 601
P+LA+++SV + + D NDNAP+V+ P P
Sbjct: 544 TPVLATNISVNIFVTDRNDNAPQVLYP------------------------------RPG 573
Query: 602 GTDTPPLATHSSRPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVT 661
G+ L +S L++ +V DAD+G N YS+ LF + HTGQ+
Sbjct: 574 GSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTGQI-STAR 632
Query: 662 NASSLIGSEWELEIVVEDQGSPPLQTRALLRVMFVTSVDHLR---DSARKPGALSMSMLT 718
L ++++D G P L T A L V R S P ++
Sbjct: 633 PVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAPREQKKNLTF 692
Query: 719 VICLAVLLGIFGLILALFMSICRTEKKDNRAYNCREAESTYR 760
+ L+++L G ++ +F I + Y +++ YR
Sbjct: 693 YLLLSLILVSVGFVVTVFGVII------FKVYKWKQSRDLYR 728
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,138,714
Number of Sequences: 37866
Number of extensions: 2488858
Number of successful extensions: 13247
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 194
Number of HSP's successfully gapped in prelim test: 87
Number of HSP's that attempted gapping in prelim test: 6414
Number of HSP's gapped (non-prelim): 1260
length of query: 1184
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1071
effective length of database: 13,968,660
effective search space: 14960434860
effective search space used: 14960434860
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.