Guide to the Human Genome
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Search of human proteins with 13994335

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13994335 Mix-like homeobox protein 1 [Homo sapiens]
         (232 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13994335 Mix-like homeobox protein 1 [Homo sapiens]                474   e-134
gi|126116581 retina and anterior neural fold homeobox [Homo sapi...    92   4e-19
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]                 90   2e-18
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]                  90   2e-18
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]                  90   2e-18
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]                  90   2e-18
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]                  90   2e-18
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]                   90   2e-18
gi|4885363 goosecoid homeobox 2 [Homo sapiens]                         85   6e-17
gi|4505619 paired box 7 isoform 1 [Homo sapiens]                       84   8e-17
gi|7524359 paired box 7 isoform 2 [Homo sapiens]                       84   8e-17
gi|207029223 paired box 7 isoform 3 [Homo sapiens]                     84   8e-17
gi|20070107 orthodenticle homeobox 1 [Homo sapiens]                    84   1e-16
gi|57232759 intestine-specific homeobox [Homo sapiens]                 84   1e-16
gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens]          83   2e-16
gi|7706659 paired related homeobox 2 [Homo sapiens]                    82   3e-16
gi|169881277 PROP paired-like homeobox 1 [Homo sapiens]                82   4e-16
gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens]          82   4e-16
gi|14249388 retina and anterior neural fold homeobox 2 [Homo sap...    82   5e-16
gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom...    81   9e-16
gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Hom...    81   9e-16
gi|113204604 aristaless-like homeobox 3 [Homo sapiens]                 80   1e-15
gi|55743092 aristaless-like homeobox 4 [Homo sapiens]                  80   2e-15
gi|46249382 paired-like homeobox 2a [Homo sapiens]                     79   3e-15
gi|152963644 paired-like homeodomain transcription factor 1 [Hom...    79   4e-15
gi|11056038 visual system homeobox 1 isoform a [Homo sapiens]          79   4e-15
gi|4826912 paired-like homeodomain 3 [Homo sapiens]                    77   1e-14
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]             77   1e-14
gi|4557489 cone-rod homeobox protein [Homo sapiens]                    77   1e-14
gi|14149760 orthopedia homeobox [Homo sapiens]                         77   1e-14

>gi|13994335 Mix-like homeobox protein 1 [Homo sapiens]
          Length = 232

 Score =  474 bits (1221), Expect = e-134
 Identities = 232/232 (100%), Positives = 232/232 (100%)

Query: 1   MATAESRALQFAEGAAFPAYRAPHAGGALLPPPSPAAALLPAPPAGPGPATFAGFLGRDP 60
           MATAESRALQFAEGAAFPAYRAPHAGGALLPPPSPAAALLPAPPAGPGPATFAGFLGRDP
Sbjct: 1   MATAESRALQFAEGAAFPAYRAPHAGGALLPPPSPAAALLPAPPAGPGPATFAGFLGRDP 60

Query: 61  GPAPPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLA 120
           GPAPPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLA
Sbjct: 61  GPAPPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLA 120

Query: 121 ALTLLPESRIQVWFQNRRAKSRRQSGKSFQPLARPEIILNHCAPGTETKCLKPQLPLEVD 180
           ALTLLPESRIQVWFQNRRAKSRRQSGKSFQPLARPEIILNHCAPGTETKCLKPQLPLEVD
Sbjct: 121 ALTLLPESRIQVWFQNRRAKSRRQSGKSFQPLARPEIILNHCAPGTETKCLKPQLPLEVD 180

Query: 181 VNCLPEPNGVGGGISDSSSQGQNFETCSPLSEDIGSKLDSWEEHIFSAFGNF 232
           VNCLPEPNGVGGGISDSSSQGQNFETCSPLSEDIGSKLDSWEEHIFSAFGNF
Sbjct: 181 VNCLPEPNGVGGGISDSSSQGQNFETCSPLSEDIGSKLDSWEEHIFSAFGNF 232


>gi|126116581 retina and anterior neural fold homeobox [Homo
           sapiens]
          Length = 346

 Score = 92.0 bits (227), Expect = 4e-19
 Identities = 57/136 (41%), Positives = 71/136 (52%), Gaps = 14/136 (10%)

Query: 14  GAAFPAYRAPHAGGALLPPPSPAAALLPAPP-AGPGPATFAGFLGRDPGPAPPPPASLGS 72
           GA     +AP  G    PPP+PA    PAP    P P     +  ++PG A P P     
Sbjct: 68  GARPACPKAPEEGSEPSPPPAPA----PAPEYEAPRP-----YCPKEPGEARPSPGLPVG 118

Query: 73  PAPPKGAAA----PSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPES 128
           PA  +   +    P    RR RT+F+  QL  LE  F ++ YPD++ RE LA    LPE 
Sbjct: 119 PATGEAKLSEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEV 178

Query: 129 RIQVWFQNRRAKSRRQ 144
           R+QVWFQNRRAK RRQ
Sbjct: 179 RVQVWFQNRRAKWRRQ 194



 Score = 30.8 bits (68), Expect = 1.0
 Identities = 22/61 (36%), Positives = 24/61 (39%), Gaps = 14/61 (22%)

Query: 8   ALQFAEGAAFPAYRAPHAGGALLPPPSPAAALLPAPPAGPGPATFAGFLGRDPGPAPPPP 67
           ALQ   G   PA   P    A   PP P    L +PP GPG              APPPP
Sbjct: 256 ALQSLPGFGPPAQSLP----ASYTPPPPPPPFLNSPPLGPGLQPL----------APPPP 301

Query: 68  A 68
           +
Sbjct: 302 S 302


>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
          Length = 483

 Score = 89.7 bits (221), Expect = 2e-18
 Identities = 54/137 (39%), Positives = 69/137 (50%), Gaps = 6/137 (4%)

Query: 63  APPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAAL 122
           A  P +  GS    +        QRR RT+F+AEQL+ LE  F RT YPDI+ RE LA  
Sbjct: 195 ASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQR 254

Query: 123 TLLPESRIQVWFQNRRAKSRRQSGKSFQPLARPEIILNHCAPGTETKCLKPQLPLEVDVN 182
             L E+R+QVWF NRRA+ R+Q+G      A   +  NH  PG       P LP      
Sbjct: 255 AKLTEARVQVWFSNRRARWRKQAG------ANQLMAFNHLIPGGFPPTAMPTLPTYQLSE 308

Query: 183 CLPEPNGVGGGISDSSS 199
              +P  +   +SD SS
Sbjct: 309 TSYQPTSIPQAVSDPSS 325


>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
          Length = 403

 Score = 89.7 bits (221), Expect = 2e-18
 Identities = 54/137 (39%), Positives = 69/137 (50%), Gaps = 6/137 (4%)

Query: 63  APPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAAL 122
           A  P +  GS    +        QRR RT+F+AEQL+ LE  F RT YPDI+ RE LA  
Sbjct: 196 ASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQR 255

Query: 123 TLLPESRIQVWFQNRRAKSRRQSGKSFQPLARPEIILNHCAPGTETKCLKPQLPLEVDVN 182
             L E+R+QVWF NRRA+ R+Q+G      A   +  NH  PG       P LP      
Sbjct: 256 AKLTEARVQVWFSNRRARWRKQAG------ANQLMAFNHLIPGGFPPTAMPTLPTYQLSE 309

Query: 183 CLPEPNGVGGGISDSSS 199
              +P  +   +SD SS
Sbjct: 310 TSYQPTSIPQAVSDPSS 326


>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
          Length = 407

 Score = 89.7 bits (221), Expect = 2e-18
 Identities = 54/137 (39%), Positives = 69/137 (50%), Gaps = 6/137 (4%)

Query: 63  APPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAAL 122
           A  P +  GS    +        QRR RT+F+AEQL+ LE  F RT YPDI+ RE LA  
Sbjct: 196 ASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQR 255

Query: 123 TLLPESRIQVWFQNRRAKSRRQSGKSFQPLARPEIILNHCAPGTETKCLKPQLPLEVDVN 182
             L E+R+QVWF NRRA+ R+Q+G      A   +  NH  PG       P LP      
Sbjct: 256 AKLTEARVQVWFSNRRARWRKQAG------ANQLMAFNHLIPGGFPPTAMPTLPTYQLSE 309

Query: 183 CLPEPNGVGGGISDSSS 199
              +P  +   +SD SS
Sbjct: 310 TSYQPTSIPQAVSDPSS 326


>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
          Length = 505

 Score = 89.7 bits (221), Expect = 2e-18
 Identities = 54/137 (39%), Positives = 69/137 (50%), Gaps = 6/137 (4%)

Query: 63  APPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAAL 122
           A  P +  GS    +        QRR RT+F+AEQL+ LE  F RT YPDI+ RE LA  
Sbjct: 196 ASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQR 255

Query: 123 TLLPESRIQVWFQNRRAKSRRQSGKSFQPLARPEIILNHCAPGTETKCLKPQLPLEVDVN 182
             L E+R+QVWF NRRA+ R+Q+G      A   +  NH  PG       P LP      
Sbjct: 256 AKLTEARVQVWFSNRRARWRKQAG------ANQLMAFNHLIPGGFPPTAMPTLPTYQLSE 309

Query: 183 CLPEPNGVGGGISDSSS 199
              +P  +   +SD SS
Sbjct: 310 TSYQPTSIPQAVSDPSS 326


>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
          Length = 484

 Score = 89.7 bits (221), Expect = 2e-18
 Identities = 54/137 (39%), Positives = 69/137 (50%), Gaps = 6/137 (4%)

Query: 63  APPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAAL 122
           A  P +  GS    +        QRR RT+F+AEQL+ LE  F RT YPDI+ RE LA  
Sbjct: 196 ASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQR 255

Query: 123 TLLPESRIQVWFQNRRAKSRRQSGKSFQPLARPEIILNHCAPGTETKCLKPQLPLEVDVN 182
             L E+R+QVWF NRRA+ R+Q+G      A   +  NH  PG       P LP      
Sbjct: 256 AKLTEARVQVWFSNRRARWRKQAG------ANQLMAFNHLIPGGFPPTAMPTLPTYQLSE 309

Query: 183 CLPEPNGVGGGISDSSS 199
              +P  +   +SD SS
Sbjct: 310 TSYQPTSIPQAVSDPSS 326


>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
          Length = 479

 Score = 89.7 bits (221), Expect = 2e-18
 Identities = 54/137 (39%), Positives = 69/137 (50%), Gaps = 6/137 (4%)

Query: 63  APPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAAL 122
           A  P +  GS    +        QRR RT+F+AEQL+ LE  F RT YPDI+ RE LA  
Sbjct: 196 ASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQR 255

Query: 123 TLLPESRIQVWFQNRRAKSRRQSGKSFQPLARPEIILNHCAPGTETKCLKPQLPLEVDVN 182
             L E+R+QVWF NRRA+ R+Q+G      A   +  NH  PG       P LP      
Sbjct: 256 AKLTEARVQVWFSNRRARWRKQAG------ANQLMAFNHLIPGGFPPTAMPTLPTYQLSE 309

Query: 183 CLPEPNGVGGGISDSSS 199
              +P  +   +SD SS
Sbjct: 310 TSYQPTSIPQAVSDPSS 326


>gi|4885363 goosecoid homeobox 2 [Homo sapiens]
          Length = 205

 Score = 84.7 bits (208), Expect = 6e-17
 Identities = 61/148 (41%), Positives = 69/148 (46%), Gaps = 31/148 (20%)

Query: 32  PPSPAAALLPAPPAGPG----------------------PATFAGFLGRDPGP---APPP 66
           PP PA    PA P  PG                      P   AG   R   P    P  
Sbjct: 41  PPQPAGRQSPAKPEEPGAPEAAPCACCCCCGPRAAPCGPPEAAAGLGARLAWPLRLGPAV 100

Query: 67  PASLGSPAPPKGA---AAPSASQRRKR---TSFSAEQLQLLELVFRRTRYPDIHLRERLA 120
           P SLG+PA   GA   A    SQRR R   T FS EQLQ LE +F + +YPD+  RERLA
Sbjct: 101 PLSLGAPAGGSGALPGAVGPGSQRRTRRHRTIFSEEQLQALEALFVQNQYPDVSTRERLA 160

Query: 121 ALTLLPESRIQVWFQNRRAKSRRQSGKS 148
               L E R++VWF+NRRAK R Q   S
Sbjct: 161 GRIRLREERVEVWFKNRRAKWRHQKRAS 188


>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
          Length = 520

 Score = 84.3 bits (207), Expect = 8e-17
 Identities = 46/91 (50%), Positives = 55/91 (60%), Gaps = 6/91 (6%)

Query: 86  QRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVWFQNRRAKSRRQS 145
           QRR RT+F+AEQL+ LE  F RT YPDI+ RE LA  T L E+R+QVWF NRRA+ R+Q+
Sbjct: 217 QRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQA 276

Query: 146 GKSFQPLARPEIILNHCAPGTETKCLKPQLP 176
           G      A      NH  PG       P LP
Sbjct: 277 G------ANQLAAFNHLLPGGFPPTGMPTLP 301


>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
          Length = 518

 Score = 84.3 bits (207), Expect = 8e-17
 Identities = 46/91 (50%), Positives = 55/91 (60%), Gaps = 6/91 (6%)

Query: 86  QRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVWFQNRRAKSRRQS 145
           QRR RT+F+AEQL+ LE  F RT YPDI+ RE LA  T L E+R+QVWF NRRA+ R+Q+
Sbjct: 215 QRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQA 274

Query: 146 GKSFQPLARPEIILNHCAPGTETKCLKPQLP 176
           G      A      NH  PG       P LP
Sbjct: 275 G------ANQLAAFNHLLPGGFPPTGMPTLP 299


>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
          Length = 505

 Score = 84.3 bits (207), Expect = 8e-17
 Identities = 46/91 (50%), Positives = 55/91 (60%), Gaps = 6/91 (6%)

Query: 86  QRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVWFQNRRAKSRRQS 145
           QRR RT+F+AEQL+ LE  F RT YPDI+ RE LA  T L E+R+QVWF NRRA+ R+Q+
Sbjct: 217 QRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQA 276

Query: 146 GKSFQPLARPEIILNHCAPGTETKCLKPQLP 176
           G      A      NH  PG       P LP
Sbjct: 277 G------ANQLAAFNHLLPGGFPPTGMPTLP 301


>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
          Length = 354

 Score = 84.0 bits (206), Expect = 1e-16
 Identities = 43/87 (49%), Positives = 57/87 (65%), Gaps = 7/87 (8%)

Query: 69  SLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPES 128
           S+G PA P+        QRR+RT+F+  QL +LE +F +TRYPDI +RE +A    LPES
Sbjct: 28  SVGYPATPR-------KQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPES 80

Query: 129 RIQVWFQNRRAKSRRQSGKSFQPLARP 155
           R+QVWF+NRRAK R+Q        +RP
Sbjct: 81  RVQVWFKNRRAKCRQQQQSGSGTKSRP 107


>gi|57232759 intestine-specific homeobox [Homo sapiens]
          Length = 245

 Score = 84.0 bits (206), Expect = 1e-16
 Identities = 45/102 (44%), Positives = 59/102 (57%), Gaps = 11/102 (10%)

Query: 44  PAGPGPATFAGFLGRDPGPAPPPPASLGSPAPPKGAAAPSA-SQRRKRTSFSAEQLQLLE 102
           P GPG          + GP     +  G   PPK        S+RR RT+F+ EQL  LE
Sbjct: 49  PEGPG----------EEGPGEAAASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELE 98

Query: 103 LVFRRTRYPDIHLRERLAALTLLPESRIQVWFQNRRAKSRRQ 144
            +F  T YPD+H+R +LAA   LPE+R+Q+WFQN+RAK R+Q
Sbjct: 99  KIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQ 140


>gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens]
          Length = 297

 Score = 82.8 bits (203), Expect = 2e-16
 Identities = 43/79 (54%), Positives = 58/79 (73%), Gaps = 5/79 (6%)

Query: 69  SLGSPAPPKGAAAPSAS---QRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLL 125
           S+G P P   A+ P+A+   QRR+RT+F+  QL +LE +F +TRYPDI +RE +A    L
Sbjct: 28  SVGYPGP--WASCPAATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINL 85

Query: 126 PESRIQVWFQNRRAKSRRQ 144
           PESR+QVWF+NRRAK R+Q
Sbjct: 86  PESRVQVWFKNRRAKCRQQ 104


>gi|7706659 paired related homeobox 2 [Homo sapiens]
          Length = 253

 Score = 82.4 bits (202), Expect = 3e-16
 Identities = 42/72 (58%), Positives = 51/72 (70%), Gaps = 1/72 (1%)

Query: 73  PAPPKGAAAP-SASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQ 131
           P+P +G+AA     QRR RT+F++ QLQ LE VF RT YPD  +RE LA    L E+R+Q
Sbjct: 90  PSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQ 149

Query: 132 VWFQNRRAKSRR 143
           VWFQNRRAK RR
Sbjct: 150 VWFQNRRAKFRR 161


>gi|169881277 PROP paired-like homeobox 1 [Homo sapiens]
          Length = 226

 Score = 82.0 bits (201), Expect = 4e-16
 Identities = 50/114 (43%), Positives = 57/114 (50%)

Query: 74  APPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVW 133
           +P  G      S+RR RT+FS  QL+ LE  F R +YPDI  RE LA  T L E+RIQVW
Sbjct: 57  SPQGGQRGRPHSRRRHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVW 116

Query: 134 FQNRRAKSRRQSGKSFQPLARPEIILNHCAPGTETKCLKPQLPLEVDVNCLPEP 187
           FQNRRAK R+Q     QPLA              T C          V C P P
Sbjct: 117 FQNRRAKQRKQERSLLQPLAHLSPAAFSSFLPESTACPYSYAAPPPPVTCFPHP 170


>gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens]
          Length = 289

 Score = 82.0 bits (201), Expect = 4e-16
 Identities = 41/76 (53%), Positives = 54/76 (71%), Gaps = 7/76 (9%)

Query: 69  SLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPES 128
           S+G PA P+        QRR+RT+F+  QL +LE +F +TRYPDI +RE +A    LPES
Sbjct: 28  SVGYPATPR-------KQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPES 80

Query: 129 RIQVWFQNRRAKSRRQ 144
           R+QVWF+NRRAK R+Q
Sbjct: 81  RVQVWFKNRRAKCRQQ 96


>gi|14249388 retina and anterior neural fold homeobox 2 [Homo
           sapiens]
          Length = 184

 Score = 81.6 bits (200), Expect = 5e-16
 Identities = 62/159 (38%), Positives = 71/159 (44%), Gaps = 26/159 (16%)

Query: 46  GPGPATFAGFLGRDPGPAPPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVF 105
           G GPAT  G LG                    G  AP    RR RT+F+  QL  LE  F
Sbjct: 6   GEGPATEGGGLG-------------------PGEEAPKKKHRRNRTTFTTYQLHQLERAF 46

Query: 106 RRTRYPDIHLRERLAALTLLPESRIQVWFQNRRAKSRRQ------SGKSFQPLARPEIIL 159
             + YPD++ RE LAA   LPE R+QVWFQNRRAK RRQ      SG    P       L
Sbjct: 47  EASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPAL 106

Query: 160 NHCAPGTETKCLKPQL-PLEVDVNCLPEPNGVGGGISDS 197
               P   +  L+P L P    V  LP   G G G+  S
Sbjct: 107 PFARPPAMSLPLEPWLGPGPPAVPGLPRLLGPGPGLQAS 145


>gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo
           sapiens]
          Length = 382

 Score = 80.9 bits (198), Expect = 9e-16
 Identities = 36/59 (61%), Positives = 49/59 (83%)

Query: 86  QRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVWFQNRRAKSRRQ 144
           QRR RT+F+A+QL+ LE  F++T YPD+ +RERLA  T LPE+R+QVWF+NRRAK R++
Sbjct: 71  QRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKK 129


>gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Homo
           sapiens]
          Length = 377

 Score = 80.9 bits (198), Expect = 9e-16
 Identities = 36/59 (61%), Positives = 49/59 (83%)

Query: 86  QRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVWFQNRRAKSRRQ 144
           QRR RT+F+A+QL+ LE  F++T YPD+ +RERLA  T LPE+R+QVWF+NRRAK R++
Sbjct: 66  QRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKK 124


>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
          Length = 343

 Score = 80.5 bits (197), Expect = 1e-15
 Identities = 63/179 (35%), Positives = 76/179 (42%), Gaps = 58/179 (32%)

Query: 22  APHAGGALLPPPSPAAALLPA-------------PPA------GPGPATFAGFLGRDP-- 60
           APH   A  PP  P     PA             PPA      GPGPA   G     P  
Sbjct: 35  APHLHPA--PPRGPRLTRFPACGPLEPYLPEPAKPPAKYLQDLGPGPALNGGHFYEGPAE 92

Query: 61  --------------------GPAPPPPASLGSPAP-------PKGAAAPSASQ------- 86
                               GP   P    GSP P       P     P + +       
Sbjct: 93  AEEKTSKAASFPQLPLDCRGGPRDGPSNLQGSPGPCLASLHLPLSPGLPDSMELAKNKSK 152

Query: 87  -RRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVWFQNRRAKSRRQ 144
            RR RT+FS  QL+ LE VF++T YPD++ RE+LA  T L E+R+QVWFQNRRAK R++
Sbjct: 153 KRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKR 211


>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
          Length = 411

 Score = 79.7 bits (195), Expect = 2e-15
 Identities = 39/84 (46%), Positives = 56/84 (66%)

Query: 61  GPAPPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLA 120
           GP     + L SP     + +    +RR RT+F++ QL+ LE VF++T YPD++ RE+LA
Sbjct: 189 GPQDRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLA 248

Query: 121 ALTLLPESRIQVWFQNRRAKSRRQ 144
             T L E+R+QVWFQNRRAK R++
Sbjct: 249 MRTDLTEARVQVWFQNRRAKWRKR 272


>gi|46249382 paired-like homeobox 2a [Homo sapiens]
          Length = 284

 Score = 79.0 bits (193), Expect = 3e-15
 Identities = 50/121 (41%), Positives = 58/121 (47%), Gaps = 5/121 (4%)

Query: 26  GGALLPPPSPA--AALLPAPPAGPGPATFAGFLGRDPGPAPPPPASLGSPAPPKGAAAPS 83
           GG    P  PA  AA  P P  G             P P    P       P        
Sbjct: 31  GGFQYSPLRPAFPAAGPPCPALGSSNCALGALRDHQPAPYSAVPYKF---FPEPSGLHEK 87

Query: 84  ASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVWFQNRRAKSRR 143
             QRR RT+F++ QL+ LE VF  T YPDI+ RE LA    L E+R+QVWFQNRRAK R+
Sbjct: 88  RKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRK 147

Query: 144 Q 144
           Q
Sbjct: 148 Q 148



 Score = 32.7 bits (73), Expect = 0.27
 Identities = 23/66 (34%), Positives = 27/66 (40%), Gaps = 11/66 (16%)

Query: 23  PHAGGALLPPPSPAAALLPAPPAGPGPATFAGFLGRDPGPAPPP--------PASLGSPA 74
           P +  +L PPP+P  A   +P   P P   A   G  PGP P P         A  G   
Sbjct: 186 PDSTASLPPPPAPGLA---SPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGGGG 242

Query: 75  PPKGAA 80
           P  GAA
Sbjct: 243 PGAGAA 248



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 21/43 (48%), Positives = 23/43 (53%), Gaps = 4/43 (9%)

Query: 25  AGGALLPPPSPAAALLPA-PPAGPGPATFAGFLG---RDPGPA 63
           AGG    P + AA LL A  PA  GP  F+G L    R PGPA
Sbjct: 236 AGGGGGGPGAGAAELLKAWQPAESGPGPFSGVLSSFHRKPGPA 278


>gi|152963644 paired-like homeodomain transcription factor 1 [Homo
           sapiens]
          Length = 314

 Score = 78.6 bits (192), Expect = 4e-15
 Identities = 50/131 (38%), Positives = 69/131 (52%), Gaps = 15/131 (11%)

Query: 29  LLPPPSPAAALLPA----PPAGP--------GPATFAGFLGRDPGPAPPPPASLGSPAPP 76
           L PPP P   + PA     PA P          ++      ++ G  P  P   G+    
Sbjct: 17  LRPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKERGGEPKGPEDSGAGGTG 76

Query: 77  KGAA---APSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVW 133
            G A   A    QRR+RT F+++QLQ LE  F+R RYPD+ +RE +A  T L E R++VW
Sbjct: 77  CGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVW 136

Query: 134 FQNRRAKSRRQ 144
           F+NRRAK R++
Sbjct: 137 FKNRRAKWRKR 147


>gi|11056038 visual system homeobox 1 isoform a [Homo sapiens]
          Length = 365

 Score = 78.6 bits (192), Expect = 4e-15
 Identities = 53/122 (43%), Positives = 67/122 (54%), Gaps = 15/122 (12%)

Query: 30  LPP--PSPAAALLPAPPAGPGPATFAGFLGRDPGPAPPPPASLGSPAPPKG--AAAPSAS 85
           LPP  P PAA   P  P+ P PA     LGR         +   S +  +    A+P+  
Sbjct: 109 LPPRGPEPAA---PLAPSRPPPA-----LGRQKRSDSVSTSDEDSQSEDRNDLKASPTLG 160

Query: 86  QRRKR---TSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVWFQNRRAKSR 142
           +R+KR   T F+A QL+ LE  F    YPD++ RE LA  T LPE RIQVWFQNRRAK R
Sbjct: 161 KRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWR 220

Query: 143 RQ 144
           ++
Sbjct: 221 KR 222


>gi|4826912 paired-like homeodomain 3 [Homo sapiens]
          Length = 302

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 46/111 (41%), Positives = 65/111 (58%), Gaps = 3/111 (2%)

Query: 34  SPAAALLPAPPAGPGPATFAGFLGRDPGPAPPPPASLGSPAPPKGAAAPSASQRRKRTSF 93
           SPA +L  A    P      G  G++   +    ASL   +P  G+      QRR+RT F
Sbjct: 13  SPALSLSDAGTPHPQLPEH-GCKGQEHSDSEKASASLPGGSPEDGSL--KKKQRRQRTHF 69

Query: 94  SAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVWFQNRRAKSRRQ 144
           +++QLQ LE  F+R RYPD+  RE +A  T L E+R++VWF+NRRAK R++
Sbjct: 70  TSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKR 120



 Score = 37.4 bits (85), Expect = 0.011
 Identities = 31/94 (32%), Positives = 38/94 (40%), Gaps = 10/94 (10%)

Query: 31  PPPSPAAALLP----APPAGPGPATFAGFLGRDPGPAPPPPAS------LGSPAPPKGAA 80
           PP S AA+++P    AP   PGP    G  G  PG AP   +S        S A    AA
Sbjct: 190 PPSSIAASMVPSAAAAPGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYASAAAAAAAA 249

Query: 81  APSASQRRKRTSFSAEQLQLLELVFRRTRYPDIH 114
           A S    R   + S   L+L         YP +H
Sbjct: 250 ASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVH 283


>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
          Length = 325

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 53/124 (42%), Positives = 64/124 (51%), Gaps = 10/124 (8%)

Query: 27  GALLPPPSPA--AALLPAPP---AGPGPATFAGFLGRDPGPAPPPPASLGSPAPPK-GAA 80
           G L P   P   A LLP       G  PA+ A    +DP   P P    G P P + G  
Sbjct: 43  GDLAPNSDPVEGATLLPGEDITTVGSTPASLA-VSAKDPDKQPGPQ---GGPNPSQAGQQ 98

Query: 81  APSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVWFQNRRAK 140
                Q+R RT F+  QL  LE  F +T YPDI +RE LA    L ESR+QVWFQNRRAK
Sbjct: 99  QGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAK 158

Query: 141 SRRQ 144
            +++
Sbjct: 159 WKKR 162


>gi|4557489 cone-rod homeobox protein [Homo sapiens]
          Length = 299

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 39/76 (51%), Positives = 53/76 (69%), Gaps = 2/76 (2%)

Query: 82  PSA--SQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVWFQNRRA 139
           PSA   QRR+RT+F+  QL+ LE +F +T+YPD++ RE +A    LPESR+QVWF+NRRA
Sbjct: 33  PSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRA 92

Query: 140 KSRRQSGKSFQPLARP 155
           K R+Q  +  Q    P
Sbjct: 93  KCRQQRQQQKQQQQPP 108


>gi|14149760 orthopedia homeobox [Homo sapiens]
          Length = 325

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 53/124 (42%), Positives = 64/124 (51%), Gaps = 10/124 (8%)

Query: 27  GALLPPPSPA--AALLPAPP---AGPGPATFAGFLGRDPGPAPPPPASLGSPAPPK-GAA 80
           G L P   P   A LLP       G  PA+ A    +DP   P P    G P P + G  
Sbjct: 43  GDLAPNSDPVEGATLLPGEDITTVGSTPASLA-VSAKDPDKQPGPQ---GGPNPSQAGQQ 98

Query: 81  APSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVWFQNRRAK 140
                Q+R RT F+  QL  LE  F +T YPDI +RE LA    L ESR+QVWFQNRRAK
Sbjct: 99  QGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAK 158

Query: 141 SRRQ 144
            +++
Sbjct: 159 WKKR 162


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,414,197
Number of Sequences: 37866
Number of extensions: 875130
Number of successful extensions: 20883
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 791
Number of HSP's successfully gapped in prelim test: 1217
Number of HSP's that attempted gapping in prelim test: 9168
Number of HSP's gapped (non-prelim): 8773
length of query: 232
length of database: 18,247,518
effective HSP length: 99
effective length of query: 133
effective length of database: 14,498,784
effective search space: 1928338272
effective search space used: 1928338272
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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