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Search of human proteins with 13994263
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13994263 FERM domain containing 8 [Homo sapiens]
(464 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13994263 FERM domain containing 8 [Homo sapiens] 934 0.0
gi|37221184 krev interaction trapped 1 isoform 1 [Homo sapiens] 100 2e-21
gi|37221182 krev interaction trapped 1 isoform 1 [Homo sapiens] 100 2e-21
gi|37221187 krev interaction trapped 1 isoform 1 [Homo sapiens] 100 2e-21
gi|31581522 krev interaction trapped 1 isoform 1 [Homo sapiens] 100 2e-21
gi|61742817 krev interaction trapped 1 isoform 2 [Homo sapiens] 100 2e-21
gi|156938343 talin 2 [Homo sapiens] 40 0.003
gi|223029410 talin 1 [Homo sapiens] 38 0.017
gi|117500790 FERM domain containing 3 [Homo sapiens] 38 0.022
gi|118766347 zinc finger CCCH-type domain containing 6 [Homo sap... 38 0.022
gi|22749387 zinc finger, CCHC domain containing 5 [Homo sapiens] 37 0.050
gi|21735483 transient receptor potential cation channel, subfami... 35 0.11
gi|40789265 beta 1,4-N-acetylgalactosaminyltransferase-transfera... 35 0.19
gi|21450705 leucine rich repeat containing 45 [Homo sapiens] 35 0.19
gi|87042275 erythrocyte protein band 4.1-like 4 [Homo sapiens] 33 0.55
gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens] 32 0.94
gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens] 32 0.94
gi|32967260 neurofibromin 2 isoform 5 [Homo sapiens] 32 0.94
gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens] 32 0.94
gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens] 32 0.94
gi|10092691 tight junction protein 3 [Homo sapiens] 32 0.94
gi|24307933 transcription factor EB [Homo sapiens] 32 1.6
gi|31317301 nitric oxide synthase 1 (neuronal) adaptor protein i... 31 2.7
gi|71274186 hypothetical protein LOC85449 [Homo sapiens] 31 2.7
gi|154354983 regulating synaptic membrane exocytosis 2 isoform a... 30 3.6
gi|154354981 regulating synaptic membrane exocytosis 2 isoform b... 30 3.6
gi|66392190 transmembrane protein 41B [Homo sapiens] 30 3.6
gi|221136939 pre-mRNA processing factor 31 homolog [Homo sapiens] 30 4.6
gi|110349786 Alstrom syndrome 1 [Homo sapiens] 30 4.6
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo... 30 4.6
>gi|13994263 FERM domain containing 8 [Homo sapiens]
Length = 464
Score = 934 bits (2415), Expect = 0.0
Identities = 464/464 (100%), Positives = 464/464 (100%)
Query: 1 MDGTEGSAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSLSAHELHRA 60
MDGTEGSAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSLSAHELHRA
Sbjct: 1 MDGTEGSAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSLSAHELHRA 60
Query: 61 VREVLQLPDIALDVFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDE 120
VREVLQLPDIALDVFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDE
Sbjct: 61 VREVLQLPDIALDVFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDE 120
Query: 121 PFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQL 180
PFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQL
Sbjct: 121 PFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQL 180
Query: 181 GPYQPGRPAACDLREKLDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQEV 240
GPYQPGRPAACDLREKLDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQEV
Sbjct: 181 GPYQPGRPAACDLREKLDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQEV 240
Query: 241 SSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLEG 300
SSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLEG
Sbjct: 241 SSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLEG 300
Query: 301 VHVIDSREKHVLLGLRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVNKLLKIYSKQAEL 360
VHVIDSREKHVLLGLRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVNKLLKIYSKQAEL
Sbjct: 301 VHVIDSREKHVLLGLRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVNKLLKIYSKQAEL 360
Query: 361 MSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSLAPVQRPKLRRQGSVVSSRIQHLSTI 420
MSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSLAPVQRPKLRRQGSVVSSRIQHLSTI
Sbjct: 361 MSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSLAPVQRPKLRRQGSVVSSRIQHLSTI 420
Query: 421 DYVEDGKGIRRVKPKRTTSFFSRQLSLGQGSYTVVQPGDSLEQG 464
DYVEDGKGIRRVKPKRTTSFFSRQLSLGQGSYTVVQPGDSLEQG
Sbjct: 421 DYVEDGKGIRRVKPKRTTSFFSRQLSLGQGSYTVVQPGDSLEQG 464
>gi|37221184 krev interaction trapped 1 isoform 1 [Homo sapiens]
Length = 736
Score = 100 bits (250), Expect = 2e-21
Identities = 72/263 (27%), Positives = 123/263 (46%), Gaps = 22/263 (8%)
Query: 61 VREVLQLPDIALDVFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDE 120
+ E ++L F +W+ S L +QLKP H+P + R WPE+L T+ D +
Sbjct: 447 IMEGMRLSQETQQYFTIWICSENLSLQLKPYHKPLQHVRDWPEILAELTNL---DPQRET 503
Query: 121 PFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQL 180
P L RR+V P E QI D + +L++EA+ N+L Y L +L+ ++
Sbjct: 504 PQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIVY 563
Query: 181 GPYQPGRPAACDLREK-LDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQE 239
G Y+ + L E+ L S +P K ++A +L+ Y+
Sbjct: 564 GNYESKKHKQGFLNEENLKSIVPVTKLK-------------SKAPHWTNRILHEYK---N 607
Query: 240 VSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLE 299
+S+ G + R +L C E+P YG AFF G++ A H+ PV V ++++
Sbjct: 608 LSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHK--VIPVYVGVNIK 665
Query: 300 GVHVIDSREKHVLLGLRFQELSW 322
G+H+++ K +L+ L++ W
Sbjct: 666 GLHLLNMETKALLISLKYGCFMW 688
>gi|37221182 krev interaction trapped 1 isoform 1 [Homo sapiens]
Length = 736
Score = 100 bits (250), Expect = 2e-21
Identities = 72/263 (27%), Positives = 123/263 (46%), Gaps = 22/263 (8%)
Query: 61 VREVLQLPDIALDVFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDE 120
+ E ++L F +W+ S L +QLKP H+P + R WPE+L T+ D +
Sbjct: 447 IMEGMRLSQETQQYFTIWICSENLSLQLKPYHKPLQHVRDWPEILAELTNL---DPQRET 503
Query: 121 PFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQL 180
P L RR+V P E QI D + +L++EA+ N+L Y L +L+ ++
Sbjct: 504 PQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIVY 563
Query: 181 GPYQPGRPAACDLREK-LDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQE 239
G Y+ + L E+ L S +P K ++A +L+ Y+
Sbjct: 564 GNYESKKHKQGFLNEENLKSIVPVTKLK-------------SKAPHWTNRILHEYK---N 607
Query: 240 VSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLE 299
+S+ G + R +L C E+P YG AFF G++ A H+ PV V ++++
Sbjct: 608 LSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHK--VIPVYVGVNIK 665
Query: 300 GVHVIDSREKHVLLGLRFQELSW 322
G+H+++ K +L+ L++ W
Sbjct: 666 GLHLLNMETKALLISLKYGCFMW 688
>gi|37221187 krev interaction trapped 1 isoform 1 [Homo sapiens]
Length = 736
Score = 100 bits (250), Expect = 2e-21
Identities = 72/263 (27%), Positives = 123/263 (46%), Gaps = 22/263 (8%)
Query: 61 VREVLQLPDIALDVFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDE 120
+ E ++L F +W+ S L +QLKP H+P + R WPE+L T+ D +
Sbjct: 447 IMEGMRLSQETQQYFTIWICSENLSLQLKPYHKPLQHVRDWPEILAELTNL---DPQRET 503
Query: 121 PFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQL 180
P L RR+V P E QI D + +L++EA+ N+L Y L +L+ ++
Sbjct: 504 PQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIVY 563
Query: 181 GPYQPGRPAACDLREK-LDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQE 239
G Y+ + L E+ L S +P K ++A +L+ Y+
Sbjct: 564 GNYESKKHKQGFLNEENLKSIVPVTKLK-------------SKAPHWTNRILHEYK---N 607
Query: 240 VSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLE 299
+S+ G + R +L C E+P YG AFF G++ A H+ PV V ++++
Sbjct: 608 LSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHK--VIPVYVGVNIK 665
Query: 300 GVHVIDSREKHVLLGLRFQELSW 322
G+H+++ K +L+ L++ W
Sbjct: 666 GLHLLNMETKALLISLKYGCFMW 688
>gi|31581522 krev interaction trapped 1 isoform 1 [Homo sapiens]
Length = 736
Score = 100 bits (250), Expect = 2e-21
Identities = 72/263 (27%), Positives = 123/263 (46%), Gaps = 22/263 (8%)
Query: 61 VREVLQLPDIALDVFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDE 120
+ E ++L F +W+ S L +QLKP H+P + R WPE+L T+ D +
Sbjct: 447 IMEGMRLSQETQQYFTIWICSENLSLQLKPYHKPLQHVRDWPEILAELTNL---DPQRET 503
Query: 121 PFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQL 180
P L RR+V P E QI D + +L++EA+ N+L Y L +L+ ++
Sbjct: 504 PQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIVY 563
Query: 181 GPYQPGRPAACDLREK-LDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQE 239
G Y+ + L E+ L S +P K ++A +L+ Y+
Sbjct: 564 GNYESKKHKQGFLNEENLKSIVPVTKLK-------------SKAPHWTNRILHEYK---N 607
Query: 240 VSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLE 299
+S+ G + R +L C E+P YG AFF G++ A H+ PV V ++++
Sbjct: 608 LSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHK--VIPVYVGVNIK 665
Query: 300 GVHVIDSREKHVLLGLRFQELSW 322
G+H+++ K +L+ L++ W
Sbjct: 666 GLHLLNMETKALLISLKYGCFMW 688
>gi|61742817 krev interaction trapped 1 isoform 2 [Homo sapiens]
Length = 688
Score = 100 bits (250), Expect = 2e-21
Identities = 72/263 (27%), Positives = 123/263 (46%), Gaps = 22/263 (8%)
Query: 61 VREVLQLPDIALDVFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDE 120
+ E ++L F +W+ S L +QLKP H+P + R WPE+L T+ D +
Sbjct: 399 IMEGMRLSQETQQYFTIWICSENLSLQLKPYHKPLQHVRDWPEILAELTNL---DPQRET 455
Query: 121 PFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQL 180
P L RR+V P E QI D + +L++EA+ N+L Y L +L+ ++
Sbjct: 456 PQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIVY 515
Query: 181 GPYQPGRPAACDLREK-LDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQE 239
G Y+ + L E+ L S +P K ++A +L+ Y+
Sbjct: 516 GNYESKKHKQGFLNEENLKSIVPVTKLK-------------SKAPHWTNRILHEYK---N 559
Query: 240 VSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLE 299
+S+ G + R +L C E+P YG AFF G++ A H+ PV V ++++
Sbjct: 560 LSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHK--VIPVYVGVNIK 617
Query: 300 GVHVIDSREKHVLLGLRFQELSW 322
G+H+++ K +L+ L++ W
Sbjct: 618 GLHLLNMETKALLISLKYGCFMW 640
>gi|156938343 talin 2 [Homo sapiens]
Length = 2542
Score = 40.4 bits (93), Expect = 0.003
Identities = 49/197 (24%), Positives = 79/197 (40%), Gaps = 34/197 (17%)
Query: 118 MDEPFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCR 177
+DE R FF + + D L LLY +A+ ++L +P E G +
Sbjct: 187 VDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQ 246
Query: 178 VQLGPY--QPGRPAACDLREKLDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYR 235
+Q GP+ +P DL+E FLP K+ RGA E+ + ++
Sbjct: 247 IQFGPHVEHKHKPGFLDLKE----FLPKEYIKQ----------RGA-----EKRIFQEHK 287
Query: 236 QVQEVSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVA 295
E+S EA + Y+ L YG +FF V + +G + P +
Sbjct: 288 NCGEMSE---IEAKV-----KYVKLARSLRTYGVSFF--LVKEKMKG---KNKLVPRLLG 334
Query: 296 ISLEGVHVIDSREKHVL 312
I+ + V +D + K VL
Sbjct: 335 ITKDSVMRVDEKTKEVL 351
>gi|223029410 talin 1 [Homo sapiens]
Length = 2541
Score = 38.1 bits (87), Expect = 0.017
Identities = 43/186 (23%), Positives = 73/186 (39%), Gaps = 31/186 (16%)
Query: 127 RNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQLGPYQPG 186
R FF + + D L LLY +A+ ++L +P + C++Q GP+
Sbjct: 194 RRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQ 253
Query: 187 RPAACDLREKLDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQEVSSDGGC 246
+ A L L FLP K+ GE+ + A++ ++S
Sbjct: 254 KHKAGFL--DLKDFLPKEYVKQ----------------KGERKIFQAHKNCGQMSE---I 292
Query: 247 EAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLEGVHVIDS 306
EA + Y+ L YG +FF V + +G + P + I+ E V +D
Sbjct: 293 EAKV-----RYVKLARSLKTYGVSFF--LVKEKMKG---KNKLVPRLLGITKECVMRVDE 342
Query: 307 REKHVL 312
+ K V+
Sbjct: 343 KTKEVI 348
>gi|117500790 FERM domain containing 3 [Homo sapiens]
Length = 597
Score = 37.7 bits (86), Expect = 0.022
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Query: 121 PFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQL 180
P+ R F+P L+I +E LLY + K ++ R C D LGA + + +L
Sbjct: 102 PYTMCFRVKFYP-HEPLKIKEELTRYLLYLQIKRDIFHGRLLCSFSDAAYLGACIVQAEL 160
Query: 181 GPYQP 185
G Y P
Sbjct: 161 GDYDP 165
>gi|118766347 zinc finger CCCH-type domain containing 6 [Homo
sapiens]
Length = 1189
Score = 37.7 bits (86), Expect = 0.022
Identities = 50/205 (24%), Positives = 77/205 (37%), Gaps = 33/205 (16%)
Query: 218 GRGARAGPGEQGLLNAYRQVQEVSSDGGCEAALGTHYRAYLLKCHELPFY-GCAFFHGEV 276
G + PGE L Y +Q + +Y + + + P G +HGE
Sbjct: 572 GSSYQQSPGEMQLNTNYESLQNPAE------FYDNYYAQHSIHNFQPPNNSGDGMWHGEF 625
Query: 277 ---------DKP-----AQGFLHRGGRKPVSVAISLEGVHVIDSREKHVLLGLRFQE--- 319
D P + G R G P+ V L V R V L R+QE
Sbjct: 626 AQQQPPVVQDSPNHGSGSDGSSTRTGHGPLPVPGLLPAVQ----RALFVRLTQRYQEDEE 681
Query: 320 --LSWDHTSP--EEEEPILWLEFDGDSEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAA 375
+ H +P EE++ + W + EG+ V +LK KQ E + + + ELS
Sbjct: 682 QTSTQPHRAPSKEEDDTVNWYSSSEEEEGSSVKSILKTLQKQTETLRNQQQPSTELSTPT 741
Query: 376 EPAGPQDSATGSP-SDPSSSLAPVQ 399
+P ++ + G+ DP P Q
Sbjct: 742 DPRLAKEKSKGNQVVDPRLRTIPRQ 766
>gi|22749387 zinc finger, CCHC domain containing 5 [Homo sapiens]
Length = 475
Score = 36.6 bits (83), Expect = 0.050
Identities = 35/133 (26%), Positives = 54/133 (40%), Gaps = 24/133 (18%)
Query: 301 VHVIDSREKHVLLGLRF--QELSWDHTSPEEEEPILWLEFDGDSEGTPVNKLLKIYSKQA 358
+H + E HV QEL+WD E LW++F + ++L ++ A
Sbjct: 329 IHQLCQGEGHVATHFHLIAQELNWD-------ESTLWIQFQEGLASSIQDELS--HTSPA 379
Query: 359 ELMSSLIEYCIELSQAAE--PAGPQDSATG-SPSDPSSSLAPVQRPKLRRQGSVVSSRIQ 415
+S LI CI L + + P G SA G P P + P+Q +
Sbjct: 380 TNLSDLITQCISLEEKPDPNPLGKSSSAEGDGPESPPAENQPMQ----------AAINCP 429
Query: 416 HLSTIDYVEDGKG 428
H+S ++V KG
Sbjct: 430 HISEAEWVRWHKG 442
>gi|21735483 transient receptor potential cation channel, subfamily
V, member 3 [Homo sapiens]
Length = 790
Score = 35.4 bits (80), Expect = 0.11
Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Query: 326 SPEEEEPILWLEFDGDSEGTPVNKLLK-IYSKQAELMSSLIEYCIE--LSQAAEPAGPQD 382
+P ++ +LE +G V K ++SK M S I CI P PQD
Sbjct: 35 TPTKKSAHFFLEIEGFEPNPTVAKTSPPVFSKP---MDSNIRQCISGNCDDMDSPQSPQD 91
Query: 383 SATGSPSDPSSSLAPVQRPKLRRQGSVVSSRI 414
T +PS+P+S A + + + RR+ + RI
Sbjct: 92 DVTETPSNPNSPSAQLAKEEQRRKKRRLKKRI 123
>gi|40789265 beta 1,4-N-acetylgalactosaminyltransferase-transferase
4 [Homo sapiens]
Length = 1039
Score = 34.7 bits (78), Expect = 0.19
Identities = 22/58 (37%), Positives = 33/58 (56%), Gaps = 6/58 (10%)
Query: 357 QAELMSSLIEYCIELSQAAEP-AGPQDSATGSPSDPSSSLAPVQRPKLRRQGSVVSSR 413
+ EL+ SL E ++AA P +GPQ A +P+ P ++LAP P+ R G+ SR
Sbjct: 440 EGELLDSL-----EPTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSR 492
>gi|21450705 leucine rich repeat containing 45 [Homo sapiens]
Length = 670
Score = 34.7 bits (78), Expect = 0.19
Identities = 54/199 (27%), Positives = 83/199 (41%), Gaps = 17/199 (8%)
Query: 124 QFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQLGPY 183
+FRR+ R E VL+ L++ +G + A VE C ALG L+ R L
Sbjct: 3 EFRRSYSRLCRESGAEPQEAVLQQLHQLPRGRLDLATQSLTVETCRALGKLLPRETLCTE 62
Query: 184 QPGRPAACDLREKLDSFLPAHLCKRGQSLFAALRGRGARAGPGEQ--GLLNAYRQVQEVS 241
+ C L E+ + L LC F L+G RA E LL + +Q ++
Sbjct: 63 LV--LSDCMLSEEGATLLLRGLCANTVLRFLDLKGNNLRAAGAEALGKLLQQNKSIQSLT 120
Query: 242 SDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLEG- 300
+ +LGT A+ C L G +D H+G + +A++L+G
Sbjct: 121 LEWN---SLGTWDDAFATFCGGLAANGAL---QRLDLRNNQISHKGAEE---LALALKGN 171
Query: 301 --VHVIDSREKHV-LLGLR 316
+ +D R +V LLG R
Sbjct: 172 TTLQQLDLRWNNVGLLGGR 190
>gi|87042275 erythrocyte protein band 4.1-like 4 [Homo sapiens]
Length = 686
Score = 33.1 bits (74), Expect = 0.55
Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Query: 142 EEVLRL-LYEEAKGNVLAARYPCDVEDCEALGALVCRVQLGPYQPGRPAA 190
EE+ R + + K +VL R PC V LGA + +LG Y P + A
Sbjct: 108 EEITRYQFFLQVKQDVLQGRLPCPVNTAAQLGAYAIQSELGDYDPYKHTA 157
>gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 32.3 bits (72), Expect = 0.94
Identities = 18/73 (24%), Positives = 31/73 (42%)
Query: 113 DDDVAMDEPFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALG 172
D DV+ +EP F+P+ E ++ E L + + K +L + C E L
Sbjct: 83 DHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLA 142
Query: 173 ALVCRVQLGPYQP 185
+ + + G Y P
Sbjct: 143 SYAVQAKYGDYDP 155
>gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 32.3 bits (72), Expect = 0.94
Identities = 18/73 (24%), Positives = 31/73 (42%)
Query: 113 DDDVAMDEPFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALG 172
D DV+ +EP F+P+ E ++ E L + + K +L + C E L
Sbjct: 83 DHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLA 142
Query: 173 ALVCRVQLGPYQP 185
+ + + G Y P
Sbjct: 143 SYAVQAKYGDYDP 155
>gi|32967260 neurofibromin 2 isoform 5 [Homo sapiens]
Length = 548
Score = 32.3 bits (72), Expect = 0.94
Identities = 18/73 (24%), Positives = 31/73 (42%)
Query: 113 DDDVAMDEPFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALG 172
D DV+ +EP F+P+ E ++ E L + + K +L + C E L
Sbjct: 41 DHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLA 100
Query: 173 ALVCRVQLGPYQP 185
+ + + G Y P
Sbjct: 101 SYAVQAKYGDYDP 113
>gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 32.3 bits (72), Expect = 0.94
Identities = 18/73 (24%), Positives = 31/73 (42%)
Query: 113 DDDVAMDEPFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALG 172
D DV+ +EP F+P+ E ++ E L + + K +L + C E L
Sbjct: 83 DHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLA 142
Query: 173 ALVCRVQLGPYQP 185
+ + + G Y P
Sbjct: 143 SYAVQAKYGDYDP 155
>gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens]
Length = 595
Score = 32.3 bits (72), Expect = 0.94
Identities = 18/73 (24%), Positives = 31/73 (42%)
Query: 113 DDDVAMDEPFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALG 172
D DV+ +EP F+P+ E ++ E L + + K +L + C E L
Sbjct: 83 DHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLA 142
Query: 173 ALVCRVQLGPYQP 185
+ + + G Y P
Sbjct: 143 SYAVQAKYGDYDP 155
>gi|10092691 tight junction protein 3 [Homo sapiens]
Length = 952
Score = 32.3 bits (72), Expect = 0.94
Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 341 DSEGTPVNKLLKIYSKQAELMSSLIEYCIELSQA--AEPAGPQDSATGSPSDPSSSLAPV 398
DS+ +P+ + + + + + + + + ELSQA + P A SP + S + +PV
Sbjct: 304 DSDSSPLEEGVTMADEMSSPPADISDLASELSQAPPSHIPPPPRHAQRSP-EASQTDSPV 362
Query: 399 QRPKLRRQGSVVSSRI 414
+ P+LRR+ SV S I
Sbjct: 363 ESPRLRRESSVDSRTI 378
>gi|24307933 transcription factor EB [Homo sapiens]
Length = 476
Score = 31.6 bits (70), Expect = 1.6
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 5 EGSAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSLSAHELHRA 60
EG G P P H S S+ + D++ L DD+++PLA + L S + E +A
Sbjct: 408 EGPPGYPEPLAPGHGSPFPSLSKKDLDLM--LLDDSLLPLASDPLLSTMSPEASKA 461
>gi|31317301 nitric oxide synthase 1 (neuronal) adaptor protein
isoform 1 [Homo sapiens]
Length = 506
Score = 30.8 bits (68), Expect = 2.7
Identities = 15/37 (40%), Positives = 27/37 (72%), Gaps = 1/37 (2%)
Query: 289 RKPVSVAISLEGVHVIDSREKHVLLGLRFQELSWDHT 325
+K VS+ +S++GV VI ++K +LL L+ +E +WD +
Sbjct: 69 KKKVSIMVSVDGVKVILKKKKKLLL-LQKKEWTWDES 104
>gi|71274186 hypothetical protein LOC85449 [Homo sapiens]
Length = 1200
Score = 30.8 bits (68), Expect = 2.7
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 5/69 (7%)
Query: 362 SSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSLAPVQRPK----LRRQGSVVSSRIQH- 416
SSL++ IE + A+P G AT S + V R L+R+G +R+QH
Sbjct: 736 SSLLQASIEEFEKADPPGGMQEATRCLSKSKELMEAVLRDPGLLGLQREGGATLARLQHD 795
Query: 417 LSTIDYVED 425
S +D+ D
Sbjct: 796 ASRLDFSPD 804
>gi|154354983 regulating synaptic membrane exocytosis 2 isoform a
[Homo sapiens]
Length = 1349
Score = 30.4 bits (67), Expect = 3.6
Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 15/107 (14%)
Query: 355 SKQAELMSSLIEYCIELSQAAEPAGP----QDSATGSPSDPSSSLAPVQRPKLRRQGSVV 410
S++ M + Y +E ++ A+ GP Q + SP P S P+ RP LRR S+
Sbjct: 398 SERRAAMENQRSYSMERTREAQ--GPSSYAQRTTNHSPPTPRRSPLPIDRPDLRRTDSL- 454
Query: 411 SSRIQHLSTIDYVEDGKGIRRVKPKRTTSFFSRQLSLGQGSYTVVQP 457
R QH +++ +R+ K ++ + R SL V+P
Sbjct: 455 --RKQH-----HLDPSSAVRKTKREKMETML-RNDSLSSDQSESVRP 493
>gi|154354981 regulating synaptic membrane exocytosis 2 isoform b
[Homo sapiens]
Length = 1163
Score = 30.4 bits (67), Expect = 3.6
Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 15/107 (14%)
Query: 355 SKQAELMSSLIEYCIELSQAAEPAGP----QDSATGSPSDPSSSLAPVQRPKLRRQGSVV 410
S++ M + Y +E ++ A+ GP Q + SP P S P+ RP LRR S+
Sbjct: 206 SERRAAMENQRSYSMERTREAQ--GPSSYAQRTTNHSPPTPRRSPLPIDRPDLRRTDSL- 262
Query: 411 SSRIQHLSTIDYVEDGKGIRRVKPKRTTSFFSRQLSLGQGSYTVVQP 457
R QH +++ +R+ K ++ + R SL V+P
Sbjct: 263 --RKQH-----HLDPSSAVRKTKREKMETML-RNDSLSSDQSESVRP 301
>gi|66392190 transmembrane protein 41B [Homo sapiens]
Length = 291
Score = 30.4 bits (67), Expect = 3.6
Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 6/61 (9%)
Query: 2 DGTEGSAGQPGPAERSHRSSVSSVGARAAD------VLVYLADDTVVPLAVENLPSLSAH 55
DG G+ G P R H+ S V A +A V ++L+ V+ L +N P LS
Sbjct: 22 DGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEE 81
Query: 56 E 56
E
Sbjct: 82 E 82
>gi|221136939 pre-mRNA processing factor 31 homolog [Homo sapiens]
Length = 499
Score = 30.0 bits (66), Expect = 4.6
Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 5/62 (8%)
Query: 328 EEEEPIL---WLEFDGDSEGTPVNKLLKIYSKQ--AELMSSLIEYCIELSQAAEPAGPQD 382
EEEEP + E D G V + K++ + AE+M + EY + ++A+E GP +
Sbjct: 26 EEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMFAEIMMKIEEYISKQAKASEVMGPVE 85
Query: 383 SA 384
+A
Sbjct: 86 AA 87
>gi|110349786 Alstrom syndrome 1 [Homo sapiens]
Length = 4169
Score = 30.0 bits (66), Expect = 4.6
Identities = 26/98 (26%), Positives = 49/98 (50%), Gaps = 7/98 (7%)
Query: 351 LKIYSKQAELMSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSLAPV---QRPKLRRQG 407
L ++ +QA L S L E +++S +GP D TG+P+ S+S A ++P Q
Sbjct: 818 LLVFYQQALLDSHLPEEALKVSAV---SGPADGKTGTPAVTSTSSASSSLGEKPSAFYQQ 874
Query: 408 SVVSSRIQHLSTIDYVEDGKGIRRVK-PKRTTSFFSRQ 444
++ +S + + + G G ++ P +SF+S +
Sbjct: 875 TLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHR 912
>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 457
Score = 30.0 bits (66), Expect = 4.6
Identities = 23/92 (25%), Positives = 39/92 (42%), Gaps = 23/92 (25%)
Query: 97 LGRQWPELLLRFTSAPDDDVAMDEPFLQ--FRRNVFFPKRRELQIH----DEEVLRLLYE 150
L +QW + L + PDD + +D L ++ ++FF + H D ++LR+
Sbjct: 92 LRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRI--- 148
Query: 151 EAKGNVLAA--------------RYPCDVEDC 168
GNVL + +P DV+ C
Sbjct: 149 SRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,947,574
Number of Sequences: 37866
Number of extensions: 973327
Number of successful extensions: 3282
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 3241
Number of HSP's gapped (non-prelim): 60
length of query: 464
length of database: 18,247,518
effective HSP length: 106
effective length of query: 358
effective length of database: 14,233,722
effective search space: 5095672476
effective search space used: 5095672476
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.