Guide to the Human Genome
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Search of human proteins with 7662020

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7662020 hypothetical protein LOC9766 [Homo sapiens]
         (303 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7662020 hypothetical protein LOC9766 [Homo sapiens]                615   e-176
gi|148539593 sushi domain containing 4 isoform a [Homo sapiens]       132   4e-31
gi|148886654 polydom [Homo sapiens]                                    40   0.002
gi|62739186 complement factor H isoform a precursor [Homo sapiens]     38   0.010
gi|118442839 complement factor H-related 1 [Homo sapiens]              38   0.010
gi|239758115 PREDICTED: similar to complement factor H-related 1...    38   0.010
gi|239758113 PREDICTED: similar to complement factor H-related 1...    38   0.010
gi|62739188 complement factor H isoform b precursor [Homo sapiens]     36   0.048
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap...    36   0.048
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa...    36   0.048
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap...    36   0.048
gi|5031695 H factor (complement)-like 3 [Homo sapiens]                 36   0.048
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi...    35   0.063
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi...    35   0.063
gi|42544177 complement component (3d/Epstein Barr virus) recepto...    35   0.063
gi|54792123 complement component (3d/Epstein Barr virus) recepto...    35   0.063
gi|134254450 patched isoform S [Homo sapiens]                          35   0.063
gi|134254435 patched isoform S [Homo sapiens]                          35   0.063
gi|134254468 patched isoform S [Homo sapiens]                          35   0.063
gi|134254452 patched isoform S [Homo sapiens]                          35   0.063
gi|134254432 patched isoform L' [Homo sapiens]                         35   0.063
gi|134254466 patched isoform M [Homo sapiens]                          35   0.063
gi|134254446 patched isoform L [Homo sapiens]                          35   0.063
gi|5454086 sushi-repeat-containing protein, X-linked [Homo sapiens]    35   0.063
gi|56117838 secreted frizzled-related protein 1 [Homo sapiens]         35   0.082
gi|110611237 coagulation factor XIII B subunit precursor [Homo s...    35   0.082
gi|195972857 Rho/Rac guanine nucleotide exchange factor 18 isofo...    34   0.14 
gi|41327769 Rho/Rac guanine nucleotide exchange factor 18 isofor...    34   0.14 
gi|153266841 apolipoprotein H precursor [Homo sapiens]                 34   0.14 
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]            34   0.14 

>gi|7662020 hypothetical protein LOC9766 [Homo sapiens]
          Length = 303

 Score =  615 bits (1587), Expect = e-176
 Identities = 303/303 (100%), Positives = 303/303 (100%)

Query: 1   MCHGRIAPKSTSVFAVASVGHGVFLPLVILCTLLGDGLASVCPLPPEPENGGYICHPRPC 60
           MCHGRIAPKSTSVFAVASVGHGVFLPLVILCTLLGDGLASVCPLPPEPENGGYICHPRPC
Sbjct: 1   MCHGRIAPKSTSVFAVASVGHGVFLPLVILCTLLGDGLASVCPLPPEPENGGYICHPRPC 60

Query: 61  RDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRLNEDKDTHTSLGVPTLS 120
           RDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRLNEDKDTHTSLGVPTLS
Sbjct: 61  RDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRLNEDKDTHTSLGVPTLS 120

Query: 121 IVASTASSVALILLLVVLFVLLQPKLKSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEA 180
           IVASTASSVALILLLVVLFVLLQPKLKSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEA
Sbjct: 121 IVASTASSVALILLLVVLFVLLQPKLKSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEA 180

Query: 181 VYGSSGHCVPPADPRVQIVLSEGSGPSGRSVPREQQLPDQGACSSAGGEDEAPGQSGLCE 240
           VYGSSGHCVPPADPRVQIVLSEGSGPSGRSVPREQQLPDQGACSSAGGEDEAPGQSGLCE
Sbjct: 181 VYGSSGHCVPPADPRVQIVLSEGSGPSGRSVPREQQLPDQGACSSAGGEDEAPGQSGLCE 240

Query: 241 AWGSRASETVMVHQATTSSWVAGSGNRQLAHKETADSENSDIQSLLSLTSEEYTDDIPLL 300
           AWGSRASETVMVHQATTSSWVAGSGNRQLAHKETADSENSDIQSLLSLTSEEYTDDIPLL
Sbjct: 241 AWGSRASETVMVHQATTSSWVAGSGNRQLAHKETADSENSDIQSLLSLTSEEYTDDIPLL 300

Query: 301 KEA 303
           KEA
Sbjct: 301 KEA 303


>gi|148539593 sushi domain containing 4 isoform a [Homo sapiens]
          Length = 490

 Score =  132 bits (332), Expect = 4e-31
 Identities = 82/204 (40%), Positives = 113/204 (55%), Gaps = 16/204 (7%)

Query: 41  VCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEI 100
           VCPLPP   +G ++CHPRPC +    G+V+E+ C  GY L  DYKY+TC+ GEW P+ ++
Sbjct: 242 VCPLPPMVSHGDFVCHPRPC-ERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEWFPSYQV 300

Query: 101 SCRLNED--KDTHTSLGVPTLSIVASTASSVALILLLVVLFVLLQPKLKSFHHSR-RDQG 157
            C  +E     TH +L + T  IVA TA+SV L+LLLV+L  + Q K K+    R   + 
Sbjct: 301 YCIKSEQTWPSTHETL-LTTWKIVAFTATSVLLVLLLVILARMFQTKFKAHFPPRGPPRS 359

Query: 158 VSGDQVSIMVDGVQVALPSYEEAVYGSSGHCVPPADPRVQIVLSEGSGPSGRSVPREQQL 217
            S D   ++VDGV V LPSY+EAV G      P        + S G    G  +P + Q 
Sbjct: 360 SSSDPDFVVVDGVPVMLPSYDEAVSGGLSALGP------GYMASVG---QGCPLPVDDQS 410

Query: 218 PDQGACSSAGGEDEAPGQSGLCEA 241
           P   A   +G  D  PG+S  C++
Sbjct: 411 PP--AYPGSGDTDTGPGESETCDS 432



 Score = 31.6 bits (70), Expect = 0.91
 Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 13/78 (16%)

Query: 41  VCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCK--NGE--WKP 96
           VC  P  PENG       P       GSV  + C +G+ LKG  K L  K  NG   W P
Sbjct: 56  VCADPGIPENG----FRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIP 111

Query: 97  A-----MEISCRLNEDKD 109
           +     ++  CR+ + +D
Sbjct: 112 SDNSICVQEDCRIPQIED 129


>gi|148886654 polydom [Homo sapiens]
          Length = 3571

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 11/77 (14%)

Query: 42   CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWK----PA 97
            C +PP  ENG +        D   AGS + Y C  GY L GD +     NG W       
Sbjct: 1690 CGVPPPLENGFHSA------DDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSC 1743

Query: 98   MEI-SCRLNEDKDTHTS 113
            +++  C +  D   H S
Sbjct: 1744 LDVDECAVGSDCSEHAS 1760



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 4/66 (6%)

Query: 38   LASVCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPA 97
            +A  C  PP      Y       +    AGSV+ + C EG++L    K    + G+W P+
Sbjct: 2079 IAHFCEKPPSVS---YSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPS 2135

Query: 98   -MEISC 102
             M I C
Sbjct: 2136 PMSIQC 2141



 Score = 35.8 bits (81), Expect = 0.048
 Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 6/53 (11%)

Query: 42   CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEW 94
            C  P  PENG          +  T G+ + + C EGY L G  K    ++GEW
Sbjct: 1789 CKAPGNPENG------HSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEW 1835



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 6/61 (9%)

Query: 42   CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEIS 101
            C  PP  +NG          +    GS +++ C EGY L GD  +   K+G+W       
Sbjct: 2264 CGKPPPIQNGFMK------GENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPK 2317

Query: 102  C 102
            C
Sbjct: 2318 C 2318



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 6/56 (10%)

Query: 42   CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPA 97
            C  PP   NG      +   D  T    IEY C EG++L+G    +   NG W  A
Sbjct: 2833 CSSPPVSANG------QVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGA 2882



 Score = 32.7 bits (73), Expect = 0.41
 Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 10/55 (18%)

Query: 42   CPLPPEPENGGYICHPRPCRDPL--TAGSVIEYLCAEGYMLKGDYKYLTCKNGEW 94
            C  P  PENG        C + L  T GS + Y C +GY L GD +     N  W
Sbjct: 1847 CGKPAIPENG--------CIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSW 1893



 Score = 32.7 bits (73), Expect = 0.41
 Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 10/66 (15%)

Query: 42   CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAM--- 98
            C LP  PENG             + GS ++Y C  G++L G    L  +N +W  A    
Sbjct: 2717 CDLPTAPENGFLRF------TETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRC 2770

Query: 99   -EISCR 103
              ISC+
Sbjct: 2771 EAISCK 2776



 Score = 32.0 bits (71), Expect = 0.69
 Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 9/60 (15%)

Query: 40  SVCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYML---KGDYKYLTCKNGEWKP 96
           S C +P  P NG +IC P         G      C EGY       D  Y   ++G WKP
Sbjct: 725 SPCEIPFTPVNGDFICTPD------NTGVNCTLTCLEGYDFTEGSTDKYYCAYEDGVWKP 778



 Score = 32.0 bits (71), Expect = 0.69
 Identities = 15/39 (38%), Positives = 20/39 (51%), Gaps = 2/39 (5%)

Query: 67   GSVIEYLCAEGYMLKGDYKYLTCKNGEW--KPAMEISCR 103
            G +I Y C  GYML+G  + +  +NG W   P     CR
Sbjct: 3435 GDMITYSCYSGYMLEGFLRSVCLENGTWTSPPICRAVCR 3473



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 19/62 (30%), Positives = 25/62 (40%), Gaps = 14/62 (22%)

Query: 54   ICHPRPCRDPLTAG------------SVIEYLCAEGYMLKGDYKYLTC-KNGEWKPAMEI 100
            +C P  C  P +              S ++  C EGY +  D    TC K+G W P   I
Sbjct: 3116 VCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPE-RI 3174

Query: 101  SC 102
            SC
Sbjct: 3175 SC 3176



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 21/77 (27%), Positives = 29/77 (37%), Gaps = 13/77 (16%)

Query: 41   VCPLPPEPENGGYICHPRPCRDPL------------TAGSVIEYLCAEGYMLKGDYKYLT 88
            VC    +   G  IC    C  PL            T G  + Y C  GY L+G  +   
Sbjct: 3280 VCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHC 3339

Query: 89   CKNGEWKPAMEISCRLN 105
             +NG W   + + C+ N
Sbjct: 3340 TENGTWSHPVPL-CKPN 3355



 Score = 28.9 bits (63), Expect = 5.9
 Identities = 17/59 (28%), Positives = 26/59 (44%), Gaps = 6/59 (10%)

Query: 42   CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEI 100
            C  P  PE+G  +          T  S I Y C  GY L+G+ + +  +N +W   + I
Sbjct: 3241 CGKPESPEHGFVV------GSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAI 3293



 Score = 28.5 bits (62), Expect = 7.7
 Identities = 17/59 (28%), Positives = 24/59 (40%), Gaps = 6/59 (10%)

Query: 38   LASVCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKP 96
            LA  C  PP       + H  P       G +  Y C++GY L  + + L    G+W P
Sbjct: 2017 LAVSCDEPP------IVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVP 2069


>gi|62739186 complement factor H isoform a precursor [Homo sapiens]
          Length = 1231

 Score = 38.1 bits (87), Expect = 0.010
 Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 4/53 (7%)

Query: 42   CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEW 94
            C  PP  +NG     P     P    S +EY C   Y L+G+ K +TC+NG+W
Sbjct: 1109 CGPPPPIDNGDITSFPLSVYAP---ASSVEYQCQNLYQLEGN-KRITCRNGQW 1157



 Score = 35.8 bits (81), Expect = 0.048
 Identities = 20/55 (36%), Positives = 22/55 (40%), Gaps = 15/55 (27%)

Query: 55  CHPRPCRDP---------LTAGSVIEY------LCAEGYMLKGDYKYLTCKNGEW 94
           C  RPC  P         LT G+V EY       C EGY L G+  Y  C    W
Sbjct: 80  CQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGW 134



 Score = 32.0 bits (71), Expect = 0.69
 Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 4/60 (6%)

Query: 48  PENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEW---KP-AMEISCR 103
           PENG  +            G  + ++C  GY ++GD +     +G W   KP  +EISC+
Sbjct: 152 PENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCK 211



 Score = 31.6 bits (70), Expect = 0.91
 Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 4/53 (7%)

Query: 42  CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEW 94
           C  PPE  NG         ++      V+EY C   +++KG  K + C +GEW
Sbjct: 630 CGPPPELLNGNV---KEKTKEEYGHSEVVEYYCNPRFLMKGPNK-IQCVDGEW 678


>gi|118442839 complement factor H-related 1 [Homo sapiens]
          Length = 330

 Score = 38.1 bits (87), Expect = 0.010
 Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 4/53 (7%)

Query: 42  CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEW 94
           C  PP  +NG     P     P    S +EY C   Y L+G+ K +TC+NG+W
Sbjct: 208 CGPPPPIDNGDITSFPLSVYAP---ASSVEYQCQNLYQLEGN-KRITCRNGQW 256


>gi|239758115 PREDICTED: similar to complement factor H-related 1
           isoform 2 [Homo sapiens]
          Length = 271

 Score = 38.1 bits (87), Expect = 0.010
 Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 4/53 (7%)

Query: 42  CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEW 94
           C  PP  +NG     P     P    S +EY C   Y L+G+ K +TC+NG+W
Sbjct: 149 CGPPPPIDNGDITSFPLSVYAP---ASSVEYQCQNLYQLEGN-KRITCRNGQW 197


>gi|239758113 PREDICTED: similar to complement factor H-related 1
           isoform 1 [Homo sapiens]
          Length = 330

 Score = 38.1 bits (87), Expect = 0.010
 Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 4/53 (7%)

Query: 42  CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEW 94
           C  PP  +NG     P     P    S +EY C   Y L+G+ K +TC+NG+W
Sbjct: 208 CGPPPPIDNGDITSFPLSVYAP---ASSVEYQCQNLYQLEGN-KRITCRNGQW 256


>gi|62739188 complement factor H isoform b precursor [Homo sapiens]
          Length = 449

 Score = 35.8 bits (81), Expect = 0.048
 Identities = 20/55 (36%), Positives = 22/55 (40%), Gaps = 15/55 (27%)

Query: 55  CHPRPCRDP---------LTAGSVIEY------LCAEGYMLKGDYKYLTCKNGEW 94
           C  RPC  P         LT G+V EY       C EGY L G+  Y  C    W
Sbjct: 80  CQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGW 134



 Score = 32.0 bits (71), Expect = 0.69
 Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 4/60 (6%)

Query: 48  PENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEW---KP-AMEISCR 103
           PENG  +            G  + ++C  GY ++GD +     +G W   KP  +EISC+
Sbjct: 152 PENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCK 211


>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo
           sapiens]
          Length = 3667

 Score = 35.8 bits (81), Expect = 0.048
 Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 7/52 (13%)

Query: 39  ASVCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCK 90
           +++CP P EPENG  I          + GS +++ C E Y+L+G  K +TC+
Sbjct: 443 SNLCPDPGEPENGKRI------GSDFSLGSTVQFSCDEDYVLQG-AKSITCQ 487



 Score = 31.6 bits (70), Expect = 0.91
 Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 7/51 (13%)

Query: 42   CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNG 92
            CP P  P +G  I       D    G V+ + C +GY L+G + ++TC  G
Sbjct: 2012 CPEPQTPSSGIKI------GDRYMVGDVVSFQCDQGYSLQG-HSHITCMPG 2055



 Score = 28.9 bits (63), Expect = 5.9
 Identities = 13/27 (48%), Positives = 17/27 (62%), Gaps = 1/27 (3%)

Query: 67   GSVIEYLCAEGYMLKGDYKYLTCKNGE 93
            GS + Y C  GY+L+G Y  LTC  G+
Sbjct: 1680 GSTVTYYCDAGYVLQG-YSTLTCIMGD 1705



 Score = 28.5 bits (62), Expect = 7.7
 Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 1/36 (2%)

Query: 65   TAGSVIEYLCAEGYMLKGDYKYLTCKNGEW-KPAME 99
            T G+V+ Y C  GY L G    +   NG+W KP  E
Sbjct: 2914 TYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPE 2949



 Score = 28.5 bits (62), Expect = 7.7
 Identities = 24/100 (24%), Positives = 40/100 (40%), Gaps = 14/100 (14%)

Query: 60   CRDPLTAG------------SVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRLNED 107
            C DP T G            S + Y C  GY+L G  +     NG W    +  C+  + 
Sbjct: 3016 CGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSW-TGRQPECKAVQC 3074

Query: 108  KDTHTSLGVPTLSIVASTASSVALILLLVVLFVLLQPKLK 147
             +  T+       I  +T SS ++I   +  ++L  P ++
Sbjct: 3075 GNPGTTANGKVFRIDGTTFSS-SVIYSCMEGYILSGPSVR 3113


>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
           sapiens]
          Length = 3538

 Score = 35.8 bits (81), Expect = 0.048
 Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 7/52 (13%)

Query: 39  ASVCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCK 90
           +++CP P EPENG  I          + GS +++ C E Y+L+G  K +TC+
Sbjct: 379 SNLCPDPGEPENGKRI------GSDFSLGSTVQFSCDEDYVLQG-AKSITCQ 423



 Score = 31.6 bits (70), Expect = 0.91
 Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 7/51 (13%)

Query: 42   CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNG 92
            CP P  P +G  I       D    G V+ + C +GY L+G + ++TC  G
Sbjct: 1948 CPEPQTPSSGIKI------GDRYMVGDVVSFQCDQGYSLQG-HSHITCMPG 1991



 Score = 28.9 bits (63), Expect = 5.9
 Identities = 13/27 (48%), Positives = 17/27 (62%), Gaps = 1/27 (3%)

Query: 67   GSVIEYLCAEGYMLKGDYKYLTCKNGE 93
            GS + Y C  GY+L+G Y  LTC  G+
Sbjct: 1616 GSTVTYYCDAGYVLQG-YSTLTCIMGD 1641



 Score = 28.5 bits (62), Expect = 7.7
 Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 1/36 (2%)

Query: 65   TAGSVIEYLCAEGYMLKGDYKYLTCKNGEW-KPAME 99
            T G+V+ Y C  GY L G    +   NG+W KP  E
Sbjct: 2785 TYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPE 2820



 Score = 28.5 bits (62), Expect = 7.7
 Identities = 24/100 (24%), Positives = 40/100 (40%), Gaps = 14/100 (14%)

Query: 60   CRDPLTAG------------SVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRLNED 107
            C DP T G            S + Y C  GY+L G  +     NG W    +  C+  + 
Sbjct: 2887 CGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSW-TGRQPECKAVQC 2945

Query: 108  KDTHTSLGVPTLSIVASTASSVALILLLVVLFVLLQPKLK 147
             +  T+       I  +T SS ++I   +  ++L  P ++
Sbjct: 2946 GNPGTTANGKVFRIDGTTFSS-SVIYSCMEGYILSGPSVR 2984


>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo
           sapiens]
          Length = 3707

 Score = 35.8 bits (81), Expect = 0.048
 Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 7/52 (13%)

Query: 39  ASVCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCK 90
           +++CP P EPENG  I          + GS +++ C E Y+L+G  K +TC+
Sbjct: 483 SNLCPDPGEPENGKRI------GSDFSLGSTVQFSCDEDYVLQG-AKSITCQ 527



 Score = 31.6 bits (70), Expect = 0.91
 Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 7/51 (13%)

Query: 42   CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNG 92
            CP P  P +G  I       D    G V+ + C +GY L+G + ++TC  G
Sbjct: 2052 CPEPQTPSSGIKI------GDRYMVGDVVSFQCDQGYSLQG-HSHITCMPG 2095



 Score = 28.9 bits (63), Expect = 5.9
 Identities = 13/27 (48%), Positives = 17/27 (62%), Gaps = 1/27 (3%)

Query: 67   GSVIEYLCAEGYMLKGDYKYLTCKNGE 93
            GS + Y C  GY+L+G Y  LTC  G+
Sbjct: 1720 GSTVTYYCDAGYVLQG-YSTLTCIMGD 1745



 Score = 28.5 bits (62), Expect = 7.7
 Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 1/36 (2%)

Query: 65   TAGSVIEYLCAEGYMLKGDYKYLTCKNGEW-KPAME 99
            T G+V+ Y C  GY L G    +   NG+W KP  E
Sbjct: 2954 TYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPE 2989



 Score = 28.5 bits (62), Expect = 7.7
 Identities = 24/100 (24%), Positives = 40/100 (40%), Gaps = 14/100 (14%)

Query: 60   CRDPLTAG------------SVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRLNED 107
            C DP T G            S + Y C  GY+L G  +     NG W    +  C+  + 
Sbjct: 3056 CGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSW-TGRQPECKAVQC 3114

Query: 108  KDTHTSLGVPTLSIVASTASSVALILLLVVLFVLLQPKLK 147
             +  T+       I  +T SS ++I   +  ++L  P ++
Sbjct: 3115 GNPGTTANGKVFRIDGTTFSS-SVIYSCMEGYILSGPSVR 3153


>gi|5031695 H factor (complement)-like 3 [Homo sapiens]
          Length = 270

 Score = 35.8 bits (81), Expect = 0.048
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 4/56 (7%)

Query: 39  ASVCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEW 94
           A  C  PP  +NG           P   GS +EY C   Y L+G+   +TC+NG+W
Sbjct: 146 AEKCGPPPPIDNGDITSFLLSVYAP---GSSVEYQCQNLYQLEGN-NQITCRNGQW 197


>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
          Length = 2489

 Score = 35.4 bits (80), Expect = 0.063
 Identities = 26/87 (29%), Positives = 36/87 (41%), Gaps = 10/87 (11%)

Query: 20   GHGVFLPLVILCTLLGDGLASVCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYM 79
            G+GV+      C L    + + CP PP+ +NG YI        P   G  I Y+C  GY+
Sbjct: 2279 GNGVWSSPAPRCEL---SVPAACPHPPKIQNGHYIGGHVSLYLP---GMTISYICDPGYL 2332

Query: 80   LKGDYKYLTCKNGEWKP----AMEISC 102
            L G         G W        E++C
Sbjct: 2333 LVGKGFIFCTDQGIWSQLDHYCKEVNC 2359



 Score = 32.3 bits (72), Expect = 0.53
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 3/56 (5%)

Query: 41   VCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKP 96
            VC  PPE  +G    H    +D  + G  + Y C  GY L+G         G+W P
Sbjct: 1646 VCQPPPEILHGE---HTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSP 1698



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 17/62 (27%), Positives = 24/62 (38%), Gaps = 10/62 (16%)

Query: 46  PEPENGGYICHPRPC----------RDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWK 95
           PE  +   +C P P           +D  + G  + Y C  GY L+G         G+W 
Sbjct: 288 PELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWS 347

Query: 96  PA 97
           PA
Sbjct: 348 PA 349



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 17/62 (27%), Positives = 24/62 (38%), Gaps = 10/62 (16%)

Query: 46  PEPENGGYICHPRPC----------RDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWK 95
           PE  +   +C P P           +D  + G  + Y C  GY L+G         G+W 
Sbjct: 738 PELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWS 797

Query: 96  PA 97
           PA
Sbjct: 798 PA 799



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 17/62 (27%), Positives = 24/62 (38%), Gaps = 10/62 (16%)

Query: 46   PEPENGGYICHPRPC----------RDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWK 95
            PE  +   +C P P           +D  + G  + Y C  GY L+G         G+W 
Sbjct: 1188 PELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWS 1247

Query: 96   PA 97
            PA
Sbjct: 1248 PA 1249



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 17/56 (30%), Positives = 23/56 (41%), Gaps = 3/56 (5%)

Query: 41   VCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKP 96
            VC  PPE  +G    H    +D  + G  + Y C   Y L+G         G+W P
Sbjct: 2099 VCQPPPEILHGE---HTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSP 2151



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 15/60 (25%), Positives = 27/60 (45%), Gaps = 3/60 (5%)

Query: 45  PPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRL 104
           PP  ENG  +   R      +   V+E+ C  G+++KG  +       +W+P +    R+
Sbjct: 240 PPNVENGILVSDNRSL---FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 296



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 15/60 (25%), Positives = 27/60 (45%), Gaps = 3/60 (5%)

Query: 45  PPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRL 104
           PP  ENG  +   R      +   V+E+ C  G+++KG  +       +W+P +    R+
Sbjct: 690 PPNVENGILVSDNRSL---FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 746



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 15/60 (25%), Positives = 27/60 (45%), Gaps = 3/60 (5%)

Query: 45   PPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRL 104
            PP  ENG  +   R      +   V+E+ C  G+++KG  +       +W+P +    R+
Sbjct: 1140 PPNVENGILVSDNRSL---FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 1196



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 15/60 (25%), Positives = 27/60 (45%), Gaps = 3/60 (5%)

Query: 45   PPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRL 104
            PP  ENG  +   R      +   V+E+ C  G+++KG  +       +W+P +    R+
Sbjct: 1590 PPNVENGILVSDNRSL---FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 1646


>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
          Length = 2039

 Score = 35.4 bits (80), Expect = 0.063
 Identities = 26/87 (29%), Positives = 36/87 (41%), Gaps = 10/87 (11%)

Query: 20   GHGVFLPLVILCTLLGDGLASVCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYM 79
            G+GV+      C L    + + CP PP+ +NG YI        P   G  I Y+C  GY+
Sbjct: 1829 GNGVWSSPAPRCEL---SVPAACPHPPKIQNGHYIGGHVSLYLP---GMTISYICDPGYL 1882

Query: 80   LKGDYKYLTCKNGEWKP----AMEISC 102
            L G         G W        E++C
Sbjct: 1883 LVGKGFIFCTDQGIWSQLDHYCKEVNC 1909



 Score = 32.3 bits (72), Expect = 0.53
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 3/56 (5%)

Query: 41   VCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKP 96
            VC  PPE  +G    H    +D  + G  + Y C  GY L+G         G+W P
Sbjct: 1196 VCQPPPEILHGE---HTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSP 1248



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 17/62 (27%), Positives = 24/62 (38%), Gaps = 10/62 (16%)

Query: 46  PEPENGGYICHPRPC----------RDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWK 95
           PE  +   +C P P           +D  + G  + Y C  GY L+G         G+W 
Sbjct: 288 PELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWS 347

Query: 96  PA 97
           PA
Sbjct: 348 PA 349



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 17/62 (27%), Positives = 24/62 (38%), Gaps = 10/62 (16%)

Query: 46  PEPENGGYICHPRPC----------RDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWK 95
           PE  +   +C P P           +D  + G  + Y C  GY L+G         G+W 
Sbjct: 738 PELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWS 797

Query: 96  PA 97
           PA
Sbjct: 798 PA 799



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 17/56 (30%), Positives = 23/56 (41%), Gaps = 3/56 (5%)

Query: 41   VCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKP 96
            VC  PPE  +G    H    +D  + G  + Y C   Y L+G         G+W P
Sbjct: 1649 VCQPPPEILHGE---HTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSP 1701



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 15/60 (25%), Positives = 27/60 (45%), Gaps = 3/60 (5%)

Query: 45  PPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRL 104
           PP  ENG  +   R      +   V+E+ C  G+++KG  +       +W+P +    R+
Sbjct: 240 PPNVENGILVSDNRSL---FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 296



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 15/60 (25%), Positives = 27/60 (45%), Gaps = 3/60 (5%)

Query: 45  PPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRL 104
           PP  ENG  +   R      +   V+E+ C  G+++KG  +       +W+P +    R+
Sbjct: 690 PPNVENGILVSDNRSL---FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 746



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 15/60 (25%), Positives = 27/60 (45%), Gaps = 3/60 (5%)

Query: 45   PPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRL 104
            PP  ENG  +   R      +   V+E+ C  G+++KG  +       +W+P +    R+
Sbjct: 1140 PPNVENGILVSDNRSL---FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 1196


>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
           isoform 2 [Homo sapiens]
          Length = 1033

 Score = 35.4 bits (80), Expect = 0.063
 Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 7/72 (9%)

Query: 42  CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEW-KPA--- 97
           CP PP+  NG    H        + G  I Y C +GY+L G+   L    G W +PA   
Sbjct: 851 CPPPPKTPNGN---HTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC 907

Query: 98  MEISCRLNEDKD 109
            E++C    D D
Sbjct: 908 KEVNCSSPADMD 919



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 19/84 (22%), Positives = 40/84 (47%), Gaps = 10/84 (11%)

Query: 67   GSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRLNEDKDTHTSLGVPTLSIVASTA 126
            G+V+   C +GYML+G  +     + +W P + + CR         SL      I A   
Sbjct: 934  GAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAV-CR-------SRSLAPVLCGIAAGLI 985

Query: 127  SSVALILLLVVLFVLLQPKLKSFH 150
              +   L+++ L+V+ + + ++++
Sbjct: 986  --LLTFLIVITLYVISKHRARNYY 1007



 Score = 29.3 bits (64), Expect = 4.5
 Identities = 18/55 (32%), Positives = 22/55 (40%), Gaps = 3/55 (5%)

Query: 42  CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKP 96
           C  PP   NG          DP   G+ I+Y C  GY+L G+        G W P
Sbjct: 410 CQAPPNILNGQKEDRHMVRFDP---GTSIKYSCNPGYVLVGEESIQCTSEGVWTP 461


>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
           isoform 1 [Homo sapiens]
          Length = 1092

 Score = 35.4 bits (80), Expect = 0.063
 Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 7/72 (9%)

Query: 42  CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEW-KPA--- 97
           CP PP+  NG    H        + G  I Y C +GY+L G+   L    G W +PA   
Sbjct: 910 CPPPPKTPNGN---HTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC 966

Query: 98  MEISCRLNEDKD 109
            E++C    D D
Sbjct: 967 KEVNCSSPADMD 978



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 19/84 (22%), Positives = 40/84 (47%), Gaps = 10/84 (11%)

Query: 67   GSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRLNEDKDTHTSLGVPTLSIVASTA 126
            G+V+   C +GYML+G  +     + +W P + + CR         SL      I A   
Sbjct: 993  GAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAV-CR-------SRSLAPVLCGIAAGLI 1044

Query: 127  SSVALILLLVVLFVLLQPKLKSFH 150
              +   L+++ L+V+ + + ++++
Sbjct: 1045 --LLTFLIVITLYVISKHRARNYY 1066



 Score = 29.3 bits (64), Expect = 4.5
 Identities = 18/55 (32%), Positives = 22/55 (40%), Gaps = 3/55 (5%)

Query: 42  CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKP 96
           C  PP   NG          DP   G+ I+Y C  GY+L G+        G W P
Sbjct: 410 CQAPPNILNGQKEDRHMVRFDP---GTSIKYSCNPGYVLVGEESIQCTSEGVWTP 461



 Score = 29.3 bits (64), Expect = 4.5
 Identities = 10/32 (31%), Positives = 17/32 (53%)

Query: 66  AGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPA 97
           +G  ++Y C  GY+L G+       +G W P+
Sbjct: 682 SGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPS 713


>gi|134254450 patched isoform S [Homo sapiens]
          Length = 1296

 Score = 35.4 bits (80), Expect = 0.063
 Identities = 30/112 (26%), Positives = 43/112 (38%), Gaps = 10/112 (8%)

Query: 147  KSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCVPPADPRVQIVLSEGSGP 206
            +   H    QG  G    ++V+  +  + ++   V+  S H  PP++PR Q  L  GS P
Sbjct: 1085 EELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHH-PPSNPRQQPHLDSGSLP 1143

Query: 207  SG-------RSVPREQQLPDQGACSSAGGEDEAPGQSGLCE--AWGSRASET 249
             G       R  PRE   P          E    G SG      WG R + +
Sbjct: 1144 PGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARS 1195


>gi|134254435 patched isoform S [Homo sapiens]
          Length = 1296

 Score = 35.4 bits (80), Expect = 0.063
 Identities = 30/112 (26%), Positives = 43/112 (38%), Gaps = 10/112 (8%)

Query: 147  KSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCVPPADPRVQIVLSEGSGP 206
            +   H    QG  G    ++V+  +  + ++   V+  S H  PP++PR Q  L  GS P
Sbjct: 1085 EELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHH-PPSNPRQQPHLDSGSLP 1143

Query: 207  SG-------RSVPREQQLPDQGACSSAGGEDEAPGQSGLCE--AWGSRASET 249
             G       R  PRE   P          E    G SG      WG R + +
Sbjct: 1144 PGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARS 1195


>gi|134254468 patched isoform S [Homo sapiens]
          Length = 1296

 Score = 35.4 bits (80), Expect = 0.063
 Identities = 30/112 (26%), Positives = 43/112 (38%), Gaps = 10/112 (8%)

Query: 147  KSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCVPPADPRVQIVLSEGSGP 206
            +   H    QG  G    ++V+  +  + ++   V+  S H  PP++PR Q  L  GS P
Sbjct: 1085 EELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHH-PPSNPRQQPHLDSGSLP 1143

Query: 207  SG-------RSVPREQQLPDQGACSSAGGEDEAPGQSGLCE--AWGSRASET 249
             G       R  PRE   P          E    G SG      WG R + +
Sbjct: 1144 PGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARS 1195


>gi|134254452 patched isoform S [Homo sapiens]
          Length = 1296

 Score = 35.4 bits (80), Expect = 0.063
 Identities = 30/112 (26%), Positives = 43/112 (38%), Gaps = 10/112 (8%)

Query: 147  KSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCVPPADPRVQIVLSEGSGP 206
            +   H    QG  G    ++V+  +  + ++   V+  S H  PP++PR Q  L  GS P
Sbjct: 1085 EELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHH-PPSNPRQQPHLDSGSLP 1143

Query: 207  SG-------RSVPREQQLPDQGACSSAGGEDEAPGQSGLCE--AWGSRASET 249
             G       R  PRE   P          E    G SG      WG R + +
Sbjct: 1144 PGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARS 1195


>gi|134254432 patched isoform L' [Homo sapiens]
          Length = 1446

 Score = 35.4 bits (80), Expect = 0.063
 Identities = 30/112 (26%), Positives = 43/112 (38%), Gaps = 10/112 (8%)

Query: 147  KSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCVPPADPRVQIVLSEGSGP 206
            +   H    QG  G    ++V+  +  + ++   V+  S H  PP++PR Q  L  GS P
Sbjct: 1235 EELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHH-PPSNPRQQPHLDSGSLP 1293

Query: 207  SG-------RSVPREQQLPDQGACSSAGGEDEAPGQSGLCE--AWGSRASET 249
             G       R  PRE   P          E    G SG      WG R + +
Sbjct: 1294 PGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARS 1345


>gi|134254466 patched isoform M [Homo sapiens]
          Length = 1381

 Score = 35.4 bits (80), Expect = 0.063
 Identities = 30/112 (26%), Positives = 43/112 (38%), Gaps = 10/112 (8%)

Query: 147  KSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCVPPADPRVQIVLSEGSGP 206
            +   H    QG  G    ++V+  +  + ++   V+  S H  PP++PR Q  L  GS P
Sbjct: 1170 EELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHH-PPSNPRQQPHLDSGSLP 1228

Query: 207  SG-------RSVPREQQLPDQGACSSAGGEDEAPGQSGLCE--AWGSRASET 249
             G       R  PRE   P          E    G SG      WG R + +
Sbjct: 1229 PGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARS 1280


>gi|134254446 patched isoform L [Homo sapiens]
          Length = 1447

 Score = 35.4 bits (80), Expect = 0.063
 Identities = 30/112 (26%), Positives = 43/112 (38%), Gaps = 10/112 (8%)

Query: 147  KSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCVPPADPRVQIVLSEGSGP 206
            +   H    QG  G    ++V+  +  + ++   V+  S H  PP++PR Q  L  GS P
Sbjct: 1236 EELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHH-PPSNPRQQPHLDSGSLP 1294

Query: 207  SG-------RSVPREQQLPDQGACSSAGGEDEAPGQSGLCE--AWGSRASET 249
             G       R  PRE   P          E    G SG      WG R + +
Sbjct: 1295 PGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARS 1346


>gi|5454086 sushi-repeat-containing protein, X-linked [Homo sapiens]
          Length = 464

 Score = 35.4 bits (80), Expect = 0.063
 Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 6/61 (9%)

Query: 42  CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEIS 101
           CP    P NGG+      C D     S  EY C+ GY LKG+ + +TC + +       S
Sbjct: 120 CPTLAMPANGGF-----KCVDGAYFNSRCEYYCSPGYTLKGE-RTVTCMDNKAWSGRPAS 173

Query: 102 C 102
           C
Sbjct: 174 C 174


>gi|56117838 secreted frizzled-related protein 1 [Homo sapiens]
          Length = 314

 Score = 35.0 bits (79), Expect = 0.082
 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 7/79 (8%)

Query: 22  GVFLPLVILCTLLGDGLASVCPLPPEPEN-----GGYICHPRPCRDPLTAGSVIEYLCAE 76
           G + P ++ C    +G   +   PP         G  +C P  C + L + ++IE+LCA 
Sbjct: 148 GFYWPEMLKCDKFPEGDVCIAMTPPNATEASKPQGTTVCPP--CDNELKSEAIIEHLCAS 205

Query: 77  GYMLKGDYKYLTCKNGEWK 95
            + L+   K +  +NG+ K
Sbjct: 206 EFALRMKIKEVKKENGDKK 224


>gi|110611237 coagulation factor XIII B subunit precursor [Homo
           sapiens]
          Length = 661

 Score = 35.0 bits (79), Expect = 0.082
 Identities = 29/93 (31%), Positives = 40/93 (43%), Gaps = 12/93 (12%)

Query: 42  CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEIS 101
           C  PP  ENG    H +   +    G  + Y C  GY+L G  + +TC  G+W   +   
Sbjct: 336 CEEPPFIENGAANLHSKIYYN----GDKVTYACKSGYLLHGSNE-ITCNRGKW--TLPPE 388

Query: 102 CRLNEDKDTHTSL---GVPTLSIVAS--TASSV 129
           C  N +   H  +   G     I+AS  T SSV
Sbjct: 389 CVENNENCKHPPVVMNGAVADGILASYATGSSV 421



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 13/76 (17%)

Query: 44  LPPE-PENGGYICHPRPCRDPLTA---------GSVIEYLCAEGYMLKGDYKYLTCKNGE 93
           LPPE  EN     HP    +   A         GS +EY C E Y+L+G  K   C+ G+
Sbjct: 385 LPPECVENNENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGS-KISRCEQGK 443

Query: 94  WK--PAMEISCRLNED 107
           W   P     C +N D
Sbjct: 444 WSSPPVCLEPCTVNVD 459



 Score = 28.9 bits (63), Expect = 5.9
 Identities = 15/48 (31%), Positives = 21/48 (43%), Gaps = 5/48 (10%)

Query: 49  ENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKP 96
           ENG +     P +     G V+++ C E Y L G    + C N  W P
Sbjct: 220 ENGYF----HPVKQTYEEGDVVQFFCHENYYLSGS-DLIQCYNFGWYP 262


>gi|195972857 Rho/Rac guanine nucleotide exchange factor 18 isoform b
            [Homo sapiens]
          Length = 1173

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 8/96 (8%)

Query: 156  QGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCVPP----ADPRVQIVLSEGSGPSGRSV 211
            +G+ G +VS++  GV    P Y E    +     P     A   V I L   +    R  
Sbjct: 985  EGLEGPRVSMLPSGVG---PEYAERPEVARRDSAPTENRLAKSDVPIQLLSATNQFQRQA 1041

Query: 212  PREQQLPDQGACSSAGGEDEAPGQSGLCEAWGSRAS 247
              +QQ+P + A S+ GG+D+  G+S   + W S AS
Sbjct: 1042 AVQQQIPTKLAASTKGGKDKG-GKSRGSQRWESSAS 1076


>gi|41327769 Rho/Rac guanine nucleotide exchange factor 18 isoform a
           [Homo sapiens]
          Length = 1015

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 8/96 (8%)

Query: 156 QGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCVPP----ADPRVQIVLSEGSGPSGRSV 211
           +G+ G +VS++  GV    P Y E    +     P     A   V I L   +    R  
Sbjct: 827 EGLEGPRVSMLPSGVG---PEYAERPEVARRDSAPTENRLAKSDVPIQLLSATNQFQRQA 883

Query: 212 PREQQLPDQGACSSAGGEDEAPGQSGLCEAWGSRAS 247
             +QQ+P + A S+ GG+D+  G+S   + W S AS
Sbjct: 884 AVQQQIPTKLAASTKGGKDKG-GKSRGSQRWESSAS 918


>gi|153266841 apolipoprotein H precursor [Homo sapiens]
          Length = 345

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 5/71 (7%)

Query: 42  CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWK--PAME 99
           CP P  P+N G++ +  P +  L       + C +GY L G  +    K G W   P+ +
Sbjct: 205 CPFPSRPDN-GFVNY--PAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMPSCK 261

Query: 100 ISCRLNEDKDT 110
            SC++   K T
Sbjct: 262 ASCKVPVKKAT 272


>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
          Length = 3487

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 22/65 (33%), Positives = 29/65 (44%), Gaps = 16/65 (24%)

Query: 55   CHPRPCRDPLTA-------------GSVIEYLCAEGYMLKGDYKYLTCK-NGEW--KPAM 98
            C P  CR P T              G  + Y C EG+ LKG  ++ TCK +G W  KP +
Sbjct: 3185 CVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPI 3244

Query: 99   EISCR 103
             +  R
Sbjct: 3245 CLEVR 3249



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 17/50 (34%), Positives = 25/50 (50%), Gaps = 7/50 (14%)

Query: 40  SVCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTC 89
           ++CP P  PE G      +        GS +++ C EGY L+G  K +TC
Sbjct: 341 NMCPDPGIPERG------KRLGSDFRLGSSVQFTCNEGYDLQGS-KRITC 383



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 17/48 (35%), Positives = 23/48 (47%), Gaps = 6/48 (12%)

Query: 42  CPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTC 89
           CP P  P NG      +   D L  GS I +LC EG++     + +TC
Sbjct: 691 CPDPGVPVNG------KRFGDSLQLGSSISFLCDEGFLGTQGSETITC 732


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,268,716
Number of Sequences: 37866
Number of extensions: 673971
Number of successful extensions: 2022
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 69
Number of HSP's that attempted gapping in prelim test: 1807
Number of HSP's gapped (non-prelim): 278
length of query: 303
length of database: 18,247,518
effective HSP length: 102
effective length of query: 201
effective length of database: 14,385,186
effective search space: 2891422386
effective search space used: 2891422386
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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