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Search of human proteins with 7661960
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7661960 Rough Deal homolog, centromere/kinetochore protein
[Homo sapiens]
(2209 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7661960 Rough Deal homolog, centromere/kinetochore protein [H... 4355 0.0
gi|223671870 inhibitor of kappa light polypeptide gene enhancer ... 41 0.011
gi|4504631 inhibitor of kappa light polypeptide gene enhancer in... 41 0.011
gi|153792133 inhibitor of kappa light polypeptide gene enhancer ... 41 0.011
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 36 0.37
gi|46195763 metastasis suppressor 1-like [Homo sapiens] 36 0.37
gi|221316624 dystonin isoform 4 [Homo sapiens] 36 0.48
gi|221316622 dystonin isoform 3 [Homo sapiens] 36 0.48
gi|221316618 dystonin isoform 2 [Homo sapiens] 36 0.48
gi|34577047 dystonin isoform 1 [Homo sapiens] 36 0.48
gi|20357504 dystonin isoform 1eB precursor [Homo sapiens] 36 0.48
gi|34577049 dystonin isoform 1eA precursor [Homo sapiens] 36 0.48
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 36 0.48
gi|41393547 neuroblastoma-amplified protein [Homo sapiens] 35 0.82
gi|157671917 hypothetical protein LOC374864 isoform 2 [Homo sapi... 35 0.82
gi|224586784 hypothetical protein LOC731220 [Homo sapiens] 34 1.4
gi|157671919 hypothetical protein LOC374864 isoform 1 [Homo sapi... 34 1.8
gi|156616301 kelch-like 32 [Homo sapiens] 33 2.4
gi|161702986 ezrin [Homo sapiens] 33 4.1
gi|21614499 ezrin [Homo sapiens] 33 4.1
gi|217416374 hypothetical protein LOC92749 [Homo sapiens] 33 4.1
gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Ho... 33 4.1
gi|160707985 NMDA receptor regulated 1-like protein isoform 3 [H... 33 4.1
gi|157389009 hypothetical protein LOC144608 [Homo sapiens] 33 4.1
gi|93102364 SWAP-70 protein [Homo sapiens] 32 5.3
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 32 5.3
gi|27734829 hypothetical protein LOC256329 [Homo sapiens] 32 5.3
gi|41152093 zinc finger protein 644 isoform 1 [Homo sapiens] 32 5.3
gi|33356130 NMDA receptor regulated 1-like protein isoform 2 [Ho... 32 5.3
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 32 6.9
>gi|7661960 Rough Deal homolog, centromere/kinetochore protein [Homo
sapiens]
Length = 2209
Score = 4355 bits (11296), Expect = 0.0
Identities = 2209/2209 (100%), Positives = 2209/2209 (100%)
Query: 1 MWNDIELLTNDDTGSGYLSVGSRKEHGTALYQVDLLVKISSEKASLNPKIQACSLSDGFI 60
MWNDIELLTNDDTGSGYLSVGSRKEHGTALYQVDLLVKISSEKASLNPKIQACSLSDGFI
Sbjct: 1 MWNDIELLTNDDTGSGYLSVGSRKEHGTALYQVDLLVKISSEKASLNPKIQACSLSDGFI 60
Query: 61 IVADQSVILLDSICRSLQLHLVFDTEVDVVGLCQEGKFLLVGERSGNLHLIHVTSKQTLL 120
IVADQSVILLDSICRSLQLHLVFDTEVDVVGLCQEGKFLLVGERSGNLHLIHVTSKQTLL
Sbjct: 61 IVADQSVILLDSICRSLQLHLVFDTEVDVVGLCQEGKFLLVGERSGNLHLIHVTSKQTLL 120
Query: 121 TNAFVQKANDENRRTYQNLVIEKDGSNEGTYYMLLLTYSGFFCITNLQLLKIQQAIENVD 180
TNAFVQKANDENRRTYQNLVIEKDGSNEGTYYMLLLTYSGFFCITNLQLLKIQQAIENVD
Sbjct: 121 TNAFVQKANDENRRTYQNLVIEKDGSNEGTYYMLLLTYSGFFCITNLQLLKIQQAIENVD 180
Query: 181 FSTAKKLQGQIKSSFISTENYHTLGCLSLVAGDLASEVPVIIGGTGNCAFSKWEPDSSKK 240
FSTAKKLQGQIKSSFISTENYHTLGCLSLVAGDLASEVPVIIGGTGNCAFSKWEPDSSKK
Sbjct: 181 FSTAKKLQGQIKSSFISTENYHTLGCLSLVAGDLASEVPVIIGGTGNCAFSKWEPDSSKK 240
Query: 241 GMTVKNLIDAEIIKGAKKFQLIDNLLFVLDTDNVLSLWDIYTLTPVWNWPSLHVEEFLLT 300
GMTVKNLIDAEIIKGAKKFQLIDNLLFVLDTDNVLSLWDIYTLTPVWNWPSLHVEEFLLT
Sbjct: 241 GMTVKNLIDAEIIKGAKKFQLIDNLLFVLDTDNVLSLWDIYTLTPVWNWPSLHVEEFLLT 300
Query: 301 TEADSPSSVTWQGITNLKLIALTASANKKMKNLMVYSLPTMEILYSLEVSSVSSLVQTGI 360
TEADSPSSVTWQGITNLKLIALTASANKKMKNLMVYSLPTMEILYSLEVSSVSSLVQTGI
Sbjct: 301 TEADSPSSVTWQGITNLKLIALTASANKKMKNLMVYSLPTMEILYSLEVSSVSSLVQTGI 360
Query: 361 STDTIYLLEGVCKNDPKLSEDSVSVLVLRCLTEALPENRLSRLLHKHRFAEAESFAIQFG 420
STDTIYLLEGVCKNDPKLSEDSVSVLVLRCLTEALPENRLSRLLHKHRFAEAESFAIQFG
Sbjct: 361 STDTIYLLEGVCKNDPKLSEDSVSVLVLRCLTEALPENRLSRLLHKHRFAEAESFAIQFG 420
Query: 421 LDVELVYKVKSNHILEKLALSSVDASEQTEWQQLVDDAKENLHKIQDDEFVVNYCLKAQW 480
LDVELVYKVKSNHILEKLALSSVDASEQTEWQQLVDDAKENLHKIQDDEFVVNYCLKAQW
Sbjct: 421 LDVELVYKVKSNHILEKLALSSVDASEQTEWQQLVDDAKENLHKIQDDEFVVNYCLKAQW 480
Query: 481 ITYETTQEMLNYAKTRLLKKEDKTALIYSDGLKEVLRAHAKLTTFYGAFGPEKFSGSSWI 540
ITYETTQEMLNYAKTRLLKKEDKTALIYSDGLKEVLRAHAKLTTFYGAFGPEKFSGSSWI
Sbjct: 481 ITYETTQEMLNYAKTRLLKKEDKTALIYSDGLKEVLRAHAKLTTFYGAFGPEKFSGSSWI 540
Query: 541 EFLNNEDDLKDIFLQLKEGNLVCAQYLWLRHRANFESRFDVKMLESLLNSMSASVSLQKL 600
EFLNNEDDLKDIFLQLKEGNLVCAQYLWLRHRANFESRFDVKMLESLLNSMSASVSLQKL
Sbjct: 541 EFLNNEDDLKDIFLQLKEGNLVCAQYLWLRHRANFESRFDVKMLESLLNSMSASVSLQKL 600
Query: 601 CPWFKNDVIPFVRRTVPEGQIILAKWLEQAARNLELTDKANWPENGLQLAEIFFTAEKTD 660
CPWFKNDVIPFVRRTVPEGQIILAKWLEQAARNLELTDKANWPENGLQLAEIFFTAEKTD
Sbjct: 601 CPWFKNDVIPFVRRTVPEGQIILAKWLEQAARNLELTDKANWPENGLQLAEIFFTAEKTD 660
Query: 661 ELGLASSWHWISLKDYQNTEEVCQLRTLVNNLRELITLHRKYNCKLALSDFEKENTTTIV 720
ELGLASSWHWISLKDYQNTEEVCQLRTLVNNLRELITLHRKYNCKLALSDFEKENTTTIV
Sbjct: 661 ELGLASSWHWISLKDYQNTEEVCQLRTLVNNLRELITLHRKYNCKLALSDFEKENTTTIV 720
Query: 721 FRMFDKVLAPELIPSILEKFIRVYMREHDLQEEELLLLYIEDLLNRCSSKSTSLFETAWE 780
FRMFDKVLAPELIPSILEKFIRVYMREHDLQEEELLLLYIEDLLNRCSSKSTSLFETAWE
Sbjct: 721 FRMFDKVLAPELIPSILEKFIRVYMREHDLQEEELLLLYIEDLLNRCSSKSTSLFETAWE 780
Query: 781 AKAMAVIACLSDTDLIFDAVLKIMYAAVVPWSAAVEQLVKQHLEMDHPKVKLLQESYKLM 840
AKAMAVIACLSDTDLIFDAVLKIMYAAVVPWSAAVEQLVKQHLEMDHPKVKLLQESYKLM
Sbjct: 781 AKAMAVIACLSDTDLIFDAVLKIMYAAVVPWSAAVEQLVKQHLEMDHPKVKLLQESYKLM 840
Query: 841 EMKKLLRGYGIREVNLLNKEIMRVVRYILKQDVPSSLEDALKVAQAFMLSDDEIYSLRII 900
EMKKLLRGYGIREVNLLNKEIMRVVRYILKQDVPSSLEDALKVAQAFMLSDDEIYSLRII
Sbjct: 841 EMKKLLRGYGIREVNLLNKEIMRVVRYILKQDVPSSLEDALKVAQAFMLSDDEIYSLRII 900
Query: 901 DLIDREQGEDCLLLLKSLPPAEAEKTAERVIIWARLALQEEPDHSKEGKAWRMSVAKTSV 960
DLIDREQGEDCLLLLKSLPPAEAEKTAERVIIWARLALQEEPDHSKEGKAWRMSVAKTSV
Sbjct: 901 DLIDREQGEDCLLLLKSLPPAEAEKTAERVIIWARLALQEEPDHSKEGKAWRMSVAKTSV 960
Query: 961 DILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSNSSLVADLREQHI 1020
DILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSNSSLVADLREQHI
Sbjct: 961 DILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSNSSLVADLREQHI 1020
Query: 1021 KAHEVAQAKHKPGSTPEPIAAEVRSPSMESKLHRQALALQMSKQELEAELTLRALKDGNI 1080
KAHEVAQAKHKPGSTPEPIAAEVRSPSMESKLHRQALALQMSKQELEAELTLRALKDGNI
Sbjct: 1021 KAHEVAQAKHKPGSTPEPIAAEVRSPSMESKLHRQALALQMSKQELEAELTLRALKDGNI 1080
Query: 1081 KTALKKCSDLFKYHCNADTGKLLFLTCQKLCQMLADNVPVTVPVGLNLPSMIHDLASQAA 1140
KTALKKCSDLFKYHCNADTGKLLFLTCQKLCQMLADNVPVTVPVGLNLPSMIHDLASQAA
Sbjct: 1081 KTALKKCSDLFKYHCNADTGKLLFLTCQKLCQMLADNVPVTVPVGLNLPSMIHDLASQAA 1140
Query: 1141 TICSPDFLLDALELCKHTLMAVELSRQCQMDDCGILMKASFGTHKDPYEEWSYSDFFSED 1200
TICSPDFLLDALELCKHTLMAVELSRQCQMDDCGILMKASFGTHKDPYEEWSYSDFFSED
Sbjct: 1141 TICSPDFLLDALELCKHTLMAVELSRQCQMDDCGILMKASFGTHKDPYEEWSYSDFFSED 1200
Query: 1201 GIVLESQMVLPVIYELISSLVPLAESKRYPLESTSLPYCSLNEGDGLVLPVINSISALLQ 1260
GIVLESQMVLPVIYELISSLVPLAESKRYPLESTSLPYCSLNEGDGLVLPVINSISALLQ
Sbjct: 1201 GIVLESQMVLPVIYELISSLVPLAESKRYPLESTSLPYCSLNEGDGLVLPVINSISALLQ 1260
Query: 1261 NLQESSQWELALRFVVGSFGTCLQHSVSNFMNATLSEKLFGETTLVKSRHVVMELKEKAV 1320
NLQESSQWELALRFVVGSFGTCLQHSVSNFMNATLSEKLFGETTLVKSRHVVMELKEKAV
Sbjct: 1261 NLQESSQWELALRFVVGSFGTCLQHSVSNFMNATLSEKLFGETTLVKSRHVVMELKEKAV 1320
Query: 1321 IFIRENATTLLHKVFNCRLVDLDLALGYCTLLPQKDVFENLWKLIDKAWQNYDKILAISL 1380
IFIRENATTLLHKVFNCRLVDLDLALGYCTLLPQKDVFENLWKLIDKAWQNYDKILAISL
Sbjct: 1321 IFIRENATTLLHKVFNCRLVDLDLALGYCTLLPQKDVFENLWKLIDKAWQNYDKILAISL 1380
Query: 1381 VGSELASLYQEIEMGLKFRELSTDAQWGIRLGKLGISFQPVFRQHFLTKKDLIKALVENI 1440
VGSELASLYQEIEMGLKFRELSTDAQWGIRLGKLGISFQPVFRQHFLTKKDLIKALVENI
Sbjct: 1381 VGSELASLYQEIEMGLKFRELSTDAQWGIRLGKLGISFQPVFRQHFLTKKDLIKALVENI 1440
Query: 1441 DMDTSLILEYCSTFQLDCDAVLQLFIETLLHNTNAGQGQGDASMDSAKRRHPKLLAKALE 1500
DMDTSLILEYCSTFQLDCDAVLQLFIETLLHNTNAGQGQGDASMDSAKRRHPKLLAKALE
Sbjct: 1441 DMDTSLILEYCSTFQLDCDAVLQLFIETLLHNTNAGQGQGDASMDSAKRRHPKLLAKALE 1500
Query: 1501 MVPLLTSTKDLVISLSGILHKLDPYDYEMIEVVLKVIERADEKITNININQALSILKHLK 1560
MVPLLTSTKDLVISLSGILHKLDPYDYEMIEVVLKVIERADEKITNININQALSILKHLK
Sbjct: 1501 MVPLLTSTKDLVISLSGILHKLDPYDYEMIEVVLKVIERADEKITNININQALSILKHLK 1560
Query: 1561 SYRRISPPVDLEYQYMLEHVITLPSAAQTRLPFHLIFFGTAQNFWKILSTELSEESFPTL 1620
SYRRISPPVDLEYQYMLEHVITLPSAAQTRLPFHLIFFGTAQNFWKILSTELSEESFPTL
Sbjct: 1561 SYRRISPPVDLEYQYMLEHVITLPSAAQTRLPFHLIFFGTAQNFWKILSTELSEESFPTL 1620
Query: 1621 LLISKLMKFSLDTLYVSTAKHVFEKKLKPKLLKLTQAKSSTLINKEITKITQTIESCLLS 1680
LLISKLMKFSLDTLYVSTAKHVFEKKLKPKLLKLTQAKSSTLINKEITKITQTIESCLLS
Sbjct: 1621 LLISKLMKFSLDTLYVSTAKHVFEKKLKPKLLKLTQAKSSTLINKEITKITQTIESCLLS 1680
Query: 1681 IVNPEWAVAIAISLAQDIPEGSFKISALKFCLYLAERWLQNIPSQDEKREKAEALLKKLH 1740
IVNPEWAVAIAISLAQDIPEGSFKISALKFCLYLAERWLQNIPSQDEKREKAEALLKKLH
Sbjct: 1681 IVNPEWAVAIAISLAQDIPEGSFKISALKFCLYLAERWLQNIPSQDEKREKAEALLKKLH 1740
Query: 1741 IQYRRSGTEAVLIAHKLNTEEYLRVIGKPAHLIVSLYEHPSINQRIQNSSGTDYPDIHAA 1800
IQYRRSGTEAVLIAHKLNTEEYLRVIGKPAHLIVSLYEHPSINQRIQNSSGTDYPDIHAA
Sbjct: 1741 IQYRRSGTEAVLIAHKLNTEEYLRVIGKPAHLIVSLYEHPSINQRIQNSSGTDYPDIHAA 1800
Query: 1801 AKEIAEVNEINLEKVWDMLLEKWLCPSTKPGEKPSELFELQEDEALRRVQYLLLSRPIDY 1860
AKEIAEVNEINLEKVWDMLLEKWLCPSTKPGEKPSELFELQEDEALRRVQYLLLSRPIDY
Sbjct: 1801 AKEIAEVNEINLEKVWDMLLEKWLCPSTKPGEKPSELFELQEDEALRRVQYLLLSRPIDY 1860
Query: 1861 SSRMLFVFATSTTTTLGMHQLTFAHRTRALQCLFYLADKETIESLFKKPIEEVKSYLRCI 1920
SSRMLFVFATSTTTTLGMHQLTFAHRTRALQCLFYLADKETIESLFKKPIEEVKSYLRCI
Sbjct: 1861 SSRMLFVFATSTTTTLGMHQLTFAHRTRALQCLFYLADKETIESLFKKPIEEVKSYLRCI 1920
Query: 1921 TFLASFETLNIPITYELFCSSPKEGMIKGLWKNHSHESMAVRLVTELCLEYKIYDLQLWN 1980
TFLASFETLNIPITYELFCSSPKEGMIKGLWKNHSHESMAVRLVTELCLEYKIYDLQLWN
Sbjct: 1921 TFLASFETLNIPITYELFCSSPKEGMIKGLWKNHSHESMAVRLVTELCLEYKIYDLQLWN 1980
Query: 1981 GLLQKLLGFNMIPYLRKVLKAISSIHSLWQVPYFSKAWQRVIQIPLLSASCPLSPDQLSD 2040
GLLQKLLGFNMIPYLRKVLKAISSIHSLWQVPYFSKAWQRVIQIPLLSASCPLSPDQLSD
Sbjct: 1981 GLLQKLLGFNMIPYLRKVLKAISSIHSLWQVPYFSKAWQRVIQIPLLSASCPLSPDQLSD 2040
Query: 2041 CSESLIAVLECPVSGDLDLIGVARQYIQLELPAFALACLMLMPHSEKRHQQIKNFLGSCD 2100
CSESLIAVLECPVSGDLDLIGVARQYIQLELPAFALACLMLMPHSEKRHQQIKNFLGSCD
Sbjct: 2041 CSESLIAVLECPVSGDLDLIGVARQYIQLELPAFALACLMLMPHSEKRHQQIKNFLGSCD 2100
Query: 2101 PQVILKQLEEHMNTGQLAGFSHQIRSLILNNIINKKEFGILAKTKYFQMLKMHAMNTNNI 2160
PQVILKQLEEHMNTGQLAGFSHQIRSLILNNIINKKEFGILAKTKYFQMLKMHAMNTNNI
Sbjct: 2101 PQVILKQLEEHMNTGQLAGFSHQIRSLILNNIINKKEFGILAKTKYFQMLKMHAMNTNNI 2160
Query: 2161 TELVNYLANDLSLDEASVLITEYSKHCGKPVPPDTAPCEILKMFLSGLS 2209
TELVNYLANDLSLDEASVLITEYSKHCGKPVPPDTAPCEILKMFLSGLS
Sbjct: 2161 TELVNYLANDLSLDEASVLITEYSKHCGKPVPPDTAPCEILKMFLSGLS 2209
>gi|223671870 inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase gamma isoform b [Homo sapiens]
Length = 487
Score = 41.2 bits (95), Expect = 0.011
Identities = 74/319 (23%), Positives = 136/319 (42%), Gaps = 44/319 (13%)
Query: 742 RVYMREHDLQEEELLLLYIEDLLNRCSSKSTSLFETAWEAKAMAVIACLSDTDLIFDAVL 801
R+ + + DL+ ++ L + L RC + + + +A+ +++ L ++ +A
Sbjct: 174 RLGLEKLDLKRQKEQALREVEHLKRCQQQMAE-DKASVKAQVTSLLGELQESQSRLEAAT 232
Query: 802 KIMYAAVVPWSAAVEQLVKQHLEMDHPKVKLLQESYKLMEMKKLLRGYGIREVNLLNKEI 861
K A AA EQ + LE + + LQ+ + + + ++G +
Sbjct: 233 KECQALEGRARAASEQA--RQLESER---EALQQQHSVQVDQLRMQGQSVEAA------- 280
Query: 862 MRVVRYILKQDVPSSLEDALKVAQAFMLSDDEIYSLRIIDLIDREQGEDCLLLLKSLPPA 921
+R+ R ++ + + Q F D+ I S + +R++G L + L A
Sbjct: 281 LRMERQAASEEKRKLAQLQVAYHQLFQEYDNHIKSSVVGS--ERKRGMQLEDLKQQLQQA 338
Query: 922 EAEKTAERVIIWARLALQEEPDHSKEGKAWRMSVAKTSVDILKILCDIQKDNLQKKDECE 981
E A +A QE D KE +A + + +V +LK DI K + Q + +
Sbjct: 339 EE----------ALVAKQEVIDKLKE-EAEQHKIVMETVPVLKAQADIYKADFQAERQAR 387
Query: 982 EMLKLFKEVASLQENFEVFLSFEDYS-------NSSLVADLREQHIKAHEVAQAKHKPG- 1033
E L KE+ LQE E +YS S+ + D+R++H+ EV+QA P
Sbjct: 388 EKLAEKKEL--LQEQLEQLQ--REYSKLKASCQESARIEDMRKRHV---EVSQAPLPPAP 440
Query: 1034 ---STPEPIAAEVRSPSME 1049
S+P + ++ RSP E
Sbjct: 441 AYLSSPLALPSQRRSPPEE 459
>gi|4504631 inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase gamma isoform a [Homo sapiens]
Length = 419
Score = 41.2 bits (95), Expect = 0.011
Identities = 74/319 (23%), Positives = 136/319 (42%), Gaps = 44/319 (13%)
Query: 742 RVYMREHDLQEEELLLLYIEDLLNRCSSKSTSLFETAWEAKAMAVIACLSDTDLIFDAVL 801
R+ + + DL+ ++ L + L RC + + + +A+ +++ L ++ +A
Sbjct: 106 RLGLEKLDLKRQKEQALREVEHLKRCQQQMAE-DKASVKAQVTSLLGELQESQSRLEAAT 164
Query: 802 KIMYAAVVPWSAAVEQLVKQHLEMDHPKVKLLQESYKLMEMKKLLRGYGIREVNLLNKEI 861
K A AA EQ + LE + + LQ+ + + + ++G +
Sbjct: 165 KECQALEGRARAASEQA--RQLESER---EALQQQHSVQVDQLRMQGQSVEAA------- 212
Query: 862 MRVVRYILKQDVPSSLEDALKVAQAFMLSDDEIYSLRIIDLIDREQGEDCLLLLKSLPPA 921
+R+ R ++ + + Q F D+ I S + +R++G L + L A
Sbjct: 213 LRMERQAASEEKRKLAQLQVAYHQLFQEYDNHIKSSVVGS--ERKRGMQLEDLKQQLQQA 270
Query: 922 EAEKTAERVIIWARLALQEEPDHSKEGKAWRMSVAKTSVDILKILCDIQKDNLQKKDECE 981
E A +A QE D KE +A + + +V +LK DI K + Q + +
Sbjct: 271 EE----------ALVAKQEVIDKLKE-EAEQHKIVMETVPVLKAQADIYKADFQAERQAR 319
Query: 982 EMLKLFKEVASLQENFEVFLSFEDYS-------NSSLVADLREQHIKAHEVAQAKHKPG- 1033
E L KE+ LQE E +YS S+ + D+R++H+ EV+QA P
Sbjct: 320 EKLAEKKEL--LQEQLEQLQ--REYSKLKASCQESARIEDMRKRHV---EVSQAPLPPAP 372
Query: 1034 ---STPEPIAAEVRSPSME 1049
S+P + ++ RSP E
Sbjct: 373 AYLSSPLALPSQRRSPPEE 391
>gi|153792133 inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase gamma isoform a [Homo sapiens]
Length = 419
Score = 41.2 bits (95), Expect = 0.011
Identities = 74/319 (23%), Positives = 136/319 (42%), Gaps = 44/319 (13%)
Query: 742 RVYMREHDLQEEELLLLYIEDLLNRCSSKSTSLFETAWEAKAMAVIACLSDTDLIFDAVL 801
R+ + + DL+ ++ L + L RC + + + +A+ +++ L ++ +A
Sbjct: 106 RLGLEKLDLKRQKEQALREVEHLKRCQQQMAE-DKASVKAQVTSLLGELQESQSRLEAAT 164
Query: 802 KIMYAAVVPWSAAVEQLVKQHLEMDHPKVKLLQESYKLMEMKKLLRGYGIREVNLLNKEI 861
K A AA EQ + LE + + LQ+ + + + ++G +
Sbjct: 165 KECQALEGRARAASEQA--RQLESER---EALQQQHSVQVDQLRMQGQSVEAA------- 212
Query: 862 MRVVRYILKQDVPSSLEDALKVAQAFMLSDDEIYSLRIIDLIDREQGEDCLLLLKSLPPA 921
+R+ R ++ + + Q F D+ I S + +R++G L + L A
Sbjct: 213 LRMERQAASEEKRKLAQLQVAYHQLFQEYDNHIKSSVVGS--ERKRGMQLEDLKQQLQQA 270
Query: 922 EAEKTAERVIIWARLALQEEPDHSKEGKAWRMSVAKTSVDILKILCDIQKDNLQKKDECE 981
E A +A QE D KE +A + + +V +LK DI K + Q + +
Sbjct: 271 EE----------ALVAKQEVIDKLKE-EAEQHKIVMETVPVLKAQADIYKADFQAERQAR 319
Query: 982 EMLKLFKEVASLQENFEVFLSFEDYS-------NSSLVADLREQHIKAHEVAQAKHKPG- 1033
E L KE+ LQE E +YS S+ + D+R++H+ EV+QA P
Sbjct: 320 EKLAEKKEL--LQEQLEQLQ--REYSKLKASCQESARIEDMRKRHV---EVSQAPLPPAP 372
Query: 1034 ---STPEPIAAEVRSPSME 1049
S+P + ++ RSP E
Sbjct: 373 AYLSSPLALPSQRRSPPEE 391
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 36.2 bits (82), Expect = 0.37
Identities = 41/196 (20%), Positives = 79/196 (40%), Gaps = 21/196 (10%)
Query: 944 HSKEGKAWRMSVAKTSVDILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEV---- 999
H KE K +S+ + + ++ + ++ D+L+ K E+ L+ ++ L + E+
Sbjct: 710 HLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATE 769
Query: 1000 ---FLSFEDYSNSSLVADLREQHIKAHEVAQAKHKPGSTPEPIAAEVRSPSMESKLHRQA 1056
L E SS DL+++ + Q K + + + + S E+K+ +
Sbjct: 770 LSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEE 829
Query: 1057 L-------ALQMSKQELEAELTLRALKDGNIKTALKKCSDLFK-----YHCNADTGKLLF 1104
L ++ K ++E E + L +K L K SD K + GK
Sbjct: 830 LNNRIQTTVTELQKVKMEKEALMTEL--STVKDKLSKVSDSLKNSKSEFEKENQKGKAAI 887
Query: 1105 LTCQKLCQMLADNVPV 1120
L +K C+ L + V
Sbjct: 888 LDLEKTCKELKHQLQV 903
>gi|46195763 metastasis suppressor 1-like [Homo sapiens]
Length = 747
Score = 36.2 bits (82), Expect = 0.37
Identities = 26/91 (28%), Positives = 46/91 (50%), Gaps = 6/91 (6%)
Query: 928 ERVIIWARLALQEEPDHSKEGKAWRMSVAKTSVDILKILCDIQKDNLQKKDECEEMLKLF 987
ER+ W + A Q + DH+KE K R + K S D LK+ +K+ L K D ++
Sbjct: 109 ERIEDWKKAANQLDKDHAKEYKRARHEIKKKSSDTLKLQKKARKELLGKGDLQPQL---- 164
Query: 988 KEVASLQENFEVFLSFEDYSNSSLVADLREQ 1018
++LQ+ +++L E+ ++ L E+
Sbjct: 165 --DSALQDVNDMYLLLEETEKQAVRRALIEE 193
>gi|221316624 dystonin isoform 4 [Homo sapiens]
Length = 5526
Score = 35.8 bits (81), Expect = 0.48
Identities = 69/317 (21%), Positives = 125/317 (39%), Gaps = 31/317 (9%)
Query: 736 ILEKFIRVYMREHDLQEEELLLLYIEDLLNRCSSKSTSLFETAWEAKAMAVIACLSDTDL 795
I + ++ + + +L EEE+ + +++DLLN L T W + +V + L +
Sbjct: 613 IRKPLLKSSLLDQNLTEEEINMKFVQDLLNWVDEMQVQLDRTEWGSDLPSVESHLENHKN 672
Query: 796 I------FDAVLKIMYAAVVPWSAAVEQLVKQHL-EMDHPKVKLLQESYKLMEMKKLLRG 848
+ F++ LK + + +A ++ + L ++ KLL S L
Sbjct: 673 VHRAIEEFESSLKEAKISEIQMTAPLKLTYAEKLHRLESQYAKLLNTSRNQERHLDTLHN 732
Query: 849 YGIREVN---LLNKEIMRVVRYILKQDVPSSLEDALKVAQAFMLSDDEIYSLRIIDLIDR 905
+ R N LN++ V Y + + A+ D + +++ + I
Sbjct: 733 FVSRATNELIWLNEKEEEEVAYDWSERNTNIARKKDYHAELMRELDQKEENIKSVQEIAE 792
Query: 906 EQGEDCLLLLKSLP---PAEAEKTA-ERVIIWARLALQEEPDHSKEGKAW--RMSVAKTS 959
+ LLL++ P EA + A + W Q H KE A+ + AK +
Sbjct: 793 Q------LLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIKENTAYFEFFNDAKEA 846
Query: 960 VDILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSNSSLVADLREQH 1019
D L+ L KD +Q+K C+ + K +QE+ E Y S +A+L
Sbjct: 847 TDYLRNL----KDAIQRKYSCDRSSSIHKLEDLVQESMEEKEELLQY--KSTIANLMG-- 898
Query: 1020 IKAHEVAQAKHKPGSTP 1036
KA + Q K + P
Sbjct: 899 -KAKTIIQLKPRNSDCP 914
>gi|221316622 dystonin isoform 3 [Homo sapiens]
Length = 5537
Score = 35.8 bits (81), Expect = 0.48
Identities = 69/317 (21%), Positives = 125/317 (39%), Gaps = 31/317 (9%)
Query: 736 ILEKFIRVYMREHDLQEEELLLLYIEDLLNRCSSKSTSLFETAWEAKAMAVIACLSDTDL 795
I + ++ + + +L EEE+ + +++DLLN L T W + +V + L +
Sbjct: 624 IRKPLLKSSLLDQNLTEEEINMKFVQDLLNWVDEMQVQLDRTEWGSDLPSVESHLENHKN 683
Query: 796 I------FDAVLKIMYAAVVPWSAAVEQLVKQHL-EMDHPKVKLLQESYKLMEMKKLLRG 848
+ F++ LK + + +A ++ + L ++ KLL S L
Sbjct: 684 VHRAIEEFESSLKEAKISEIQMTAPLKLTYAEKLHRLESQYAKLLNTSRNQERHLDTLHN 743
Query: 849 YGIREVN---LLNKEIMRVVRYILKQDVPSSLEDALKVAQAFMLSDDEIYSLRIIDLIDR 905
+ R N LN++ V Y + + A+ D + +++ + I
Sbjct: 744 FVSRATNELIWLNEKEEEEVAYDWSERNTNIARKKDYHAELMRELDQKEENIKSVQEIAE 803
Query: 906 EQGEDCLLLLKSLP---PAEAEKTA-ERVIIWARLALQEEPDHSKEGKAW--RMSVAKTS 959
+ LLL++ P EA + A + W Q H KE A+ + AK +
Sbjct: 804 Q------LLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIKENTAYFEFFNDAKEA 857
Query: 960 VDILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSNSSLVADLREQH 1019
D L+ L KD +Q+K C+ + K +QE+ E Y S +A+L
Sbjct: 858 TDYLRNL----KDAIQRKYSCDRSSSIHKLEDLVQESMEEKEELLQY--KSTIANLMG-- 909
Query: 1020 IKAHEVAQAKHKPGSTP 1036
KA + Q K + P
Sbjct: 910 -KAKTIIQLKPRNSDCP 925
>gi|221316618 dystonin isoform 2 [Homo sapiens]
Length = 5675
Score = 35.8 bits (81), Expect = 0.48
Identities = 69/317 (21%), Positives = 125/317 (39%), Gaps = 31/317 (9%)
Query: 736 ILEKFIRVYMREHDLQEEELLLLYIEDLLNRCSSKSTSLFETAWEAKAMAVIACLSDTDL 795
I + ++ + + +L EEE+ + +++DLLN L T W + +V + L +
Sbjct: 762 IRKPLLKSSLLDQNLTEEEINMKFVQDLLNWVDEMQVQLDRTEWGSDLPSVESHLENHKN 821
Query: 796 I------FDAVLKIMYAAVVPWSAAVEQLVKQHL-EMDHPKVKLLQESYKLMEMKKLLRG 848
+ F++ LK + + +A ++ + L ++ KLL S L
Sbjct: 822 VHRAIEEFESSLKEAKISEIQMTAPLKLTYAEKLHRLESQYAKLLNTSRNQERHLDTLHN 881
Query: 849 YGIREVN---LLNKEIMRVVRYILKQDVPSSLEDALKVAQAFMLSDDEIYSLRIIDLIDR 905
+ R N LN++ V Y + + A+ D + +++ + I
Sbjct: 882 FVSRATNELIWLNEKEEEEVAYDWSERNTNIARKKDYHAELMRELDQKEENIKSVQEIAE 941
Query: 906 EQGEDCLLLLKSLP---PAEAEKTA-ERVIIWARLALQEEPDHSKEGKAW--RMSVAKTS 959
+ LLL++ P EA + A + W Q H KE A+ + AK +
Sbjct: 942 Q------LLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIKENTAYFEFFNDAKEA 995
Query: 960 VDILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSNSSLVADLREQH 1019
D L+ L KD +Q+K C+ + K +QE+ E Y S +A+L
Sbjct: 996 TDYLRNL----KDAIQRKYSCDRSSSIHKLEDLVQESMEEKEELLQY--KSTIANLMG-- 1047
Query: 1020 IKAHEVAQAKHKPGSTP 1036
KA + Q K + P
Sbjct: 1048 -KAKTIIQLKPRNSDCP 1063
>gi|34577047 dystonin isoform 1 [Homo sapiens]
Length = 5497
Score = 35.8 bits (81), Expect = 0.48
Identities = 69/317 (21%), Positives = 125/317 (39%), Gaps = 31/317 (9%)
Query: 736 ILEKFIRVYMREHDLQEEELLLLYIEDLLNRCSSKSTSLFETAWEAKAMAVIACLSDTDL 795
I + ++ + + +L EEE+ + +++DLLN L T W + +V + L +
Sbjct: 584 IRKPLLKSSLLDQNLTEEEINMKFVQDLLNWVDEMQVQLDRTEWGSDLPSVESHLENHKN 643
Query: 796 I------FDAVLKIMYAAVVPWSAAVEQLVKQHL-EMDHPKVKLLQESYKLMEMKKLLRG 848
+ F++ LK + + +A ++ + L ++ KLL S L
Sbjct: 644 VHRAIEEFESSLKEAKISEIQMTAPLKLTYAEKLHRLESQYAKLLNTSRNQERHLDTLHN 703
Query: 849 YGIREVN---LLNKEIMRVVRYILKQDVPSSLEDALKVAQAFMLSDDEIYSLRIIDLIDR 905
+ R N LN++ V Y + + A+ D + +++ + I
Sbjct: 704 FVSRATNELIWLNEKEEEEVAYDWSERNTNIARKKDYHAELMRELDQKEENIKSVQEIAE 763
Query: 906 EQGEDCLLLLKSLP---PAEAEKTA-ERVIIWARLALQEEPDHSKEGKAW--RMSVAKTS 959
+ LLL++ P EA + A + W Q H KE A+ + AK +
Sbjct: 764 Q------LLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIKENTAYFEFFNDAKEA 817
Query: 960 VDILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSNSSLVADLREQH 1019
D L+ L KD +Q+K C+ + K +QE+ E Y S +A+L
Sbjct: 818 TDYLRNL----KDAIQRKYSCDRSSSIHKLEDLVQESMEEKEELLQY--KSTIANLMG-- 869
Query: 1020 IKAHEVAQAKHKPGSTP 1036
KA + Q K + P
Sbjct: 870 -KAKTIIQLKPRNSDCP 885
>gi|20357504 dystonin isoform 1eB precursor [Homo sapiens]
Length = 3062
Score = 35.8 bits (81), Expect = 0.48
Identities = 69/317 (21%), Positives = 125/317 (39%), Gaps = 31/317 (9%)
Query: 736 ILEKFIRVYMREHDLQEEELLLLYIEDLLNRCSSKSTSLFETAWEAKAMAVIACLSDTDL 795
I + ++ + + +L EEE+ + +++DLLN L T W + +V + L +
Sbjct: 258 IRKPLLKSSLLDQNLTEEEINMKFVQDLLNWVDEMQVQLDRTEWGSDLPSVESHLENHKN 317
Query: 796 I------FDAVLKIMYAAVVPWSAAVEQLVKQHL-EMDHPKVKLLQESYKLMEMKKLLRG 848
+ F++ LK + + +A ++ + L ++ KLL S L
Sbjct: 318 VHRAIEEFESSLKEAKISEIQMTAPLKLTYAEKLHRLESQYAKLLNTSRNQERHLDTLHN 377
Query: 849 YGIREVN---LLNKEIMRVVRYILKQDVPSSLEDALKVAQAFMLSDDEIYSLRIIDLIDR 905
+ R N LN++ V Y + + A+ D + +++ + I
Sbjct: 378 FVSRATNELIWLNEKEEEEVAYDWSERNTNIARKKDYHAELMRELDQKEENIKSVQEIAE 437
Query: 906 EQGEDCLLLLKSLP---PAEAEKTA-ERVIIWARLALQEEPDHSKEGKAW--RMSVAKTS 959
+ LLL++ P EA + A + W Q H KE A+ + AK +
Sbjct: 438 Q------LLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIKENTAYFEFFNDAKEA 491
Query: 960 VDILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSNSSLVADLREQH 1019
D L+ L KD +Q+K C+ + K +QE+ E Y S +A+L
Sbjct: 492 TDYLRNL----KDAIQRKYSCDRSSSIHKLEDLVQESMEEKEELLQY--KSTIANLMG-- 543
Query: 1020 IKAHEVAQAKHKPGSTP 1036
KA + Q K + P
Sbjct: 544 -KAKTIIQLKPRNSDCP 559
>gi|34577049 dystonin isoform 1eA precursor [Homo sapiens]
Length = 5171
Score = 35.8 bits (81), Expect = 0.48
Identities = 69/317 (21%), Positives = 125/317 (39%), Gaps = 31/317 (9%)
Query: 736 ILEKFIRVYMREHDLQEEELLLLYIEDLLNRCSSKSTSLFETAWEAKAMAVIACLSDTDL 795
I + ++ + + +L EEE+ + +++DLLN L T W + +V + L +
Sbjct: 258 IRKPLLKSSLLDQNLTEEEINMKFVQDLLNWVDEMQVQLDRTEWGSDLPSVESHLENHKN 317
Query: 796 I------FDAVLKIMYAAVVPWSAAVEQLVKQHL-EMDHPKVKLLQESYKLMEMKKLLRG 848
+ F++ LK + + +A ++ + L ++ KLL S L
Sbjct: 318 VHRAIEEFESSLKEAKISEIQMTAPLKLTYAEKLHRLESQYAKLLNTSRNQERHLDTLHN 377
Query: 849 YGIREVN---LLNKEIMRVVRYILKQDVPSSLEDALKVAQAFMLSDDEIYSLRIIDLIDR 905
+ R N LN++ V Y + + A+ D + +++ + I
Sbjct: 378 FVSRATNELIWLNEKEEEEVAYDWSERNTNIARKKDYHAELMRELDQKEENIKSVQEIAE 437
Query: 906 EQGEDCLLLLKSLP---PAEAEKTA-ERVIIWARLALQEEPDHSKEGKAW--RMSVAKTS 959
+ LLL++ P EA + A + W Q H KE A+ + AK +
Sbjct: 438 Q------LLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIKENTAYFEFFNDAKEA 491
Query: 960 VDILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSNSSLVADLREQH 1019
D L+ L KD +Q+K C+ + K +QE+ E Y S +A+L
Sbjct: 492 TDYLRNL----KDAIQRKYSCDRSSSIHKLEDLVQESMEEKEELLQY--KSTIANLMG-- 543
Query: 1020 IKAHEVAQAKHKPGSTP 1036
KA + Q K + P
Sbjct: 544 -KAKTIIQLKPRNSDCP 559
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 35.8 bits (81), Expect = 0.48
Identities = 69/317 (21%), Positives = 125/317 (39%), Gaps = 31/317 (9%)
Query: 736 ILEKFIRVYMREHDLQEEELLLLYIEDLLNRCSSKSTSLFETAWEAKAMAVIACLSDTDL 795
I + ++ + + +L EEE+ + +++DLLN L T W + +V + L +
Sbjct: 258 IRKPLLKSSLLDQNLTEEEINMKFVQDLLNWVDEMQVQLDRTEWGSDLPSVESHLENHKN 317
Query: 796 I------FDAVLKIMYAAVVPWSAAVEQLVKQHL-EMDHPKVKLLQESYKLMEMKKLLRG 848
+ F++ LK + + +A ++ + L ++ KLL S L
Sbjct: 318 VHRAIEEFESSLKEAKISEIQMTAPLKLTYAEKLHRLESQYAKLLNTSRNQERHLDTLHN 377
Query: 849 YGIREVN---LLNKEIMRVVRYILKQDVPSSLEDALKVAQAFMLSDDEIYSLRIIDLIDR 905
+ R N LN++ V Y + + A+ D + +++ + I
Sbjct: 378 FVSRATNELIWLNEKEEEEVAYDWSERNTNIARKKDYHAELMRELDQKEENIKSVQEIAE 437
Query: 906 EQGEDCLLLLKSLP---PAEAEKTA-ERVIIWARLALQEEPDHSKEGKAW--RMSVAKTS 959
+ LLL++ P EA + A + W Q H KE A+ + AK +
Sbjct: 438 Q------LLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIKENTAYFEFFNDAKEA 491
Query: 960 VDILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSNSSLVADLREQH 1019
D L+ L KD +Q+K C+ + K +QE+ E Y S +A+L
Sbjct: 492 TDYLRNL----KDAIQRKYSCDRSSSIHKLEDLVQESMEEKEELLQY--KSTIANLMG-- 543
Query: 1020 IKAHEVAQAKHKPGSTP 1036
KA + Q K + P
Sbjct: 544 -KAKTIIQLKPRNSDCP 559
>gi|41393547 neuroblastoma-amplified protein [Homo sapiens]
Length = 2371
Score = 35.0 bits (79), Expect = 0.82
Identities = 31/120 (25%), Positives = 48/120 (40%), Gaps = 27/120 (22%)
Query: 391 LTEALPENRLSRLLHKHRFAEAESFAIQFGLDVELVYKVKSNHILEKLALSSVDASEQTE 450
L PE R + + EA S A +GLD +LVY Q +
Sbjct: 521 LRSTTPEELYQRKIESEEYEEALSLAHTYGLDTDLVY--------------------QRQ 560
Query: 451 WQQL---VDDAKENLHKIQDDEFVVNYCLKAQWITYETTQEMLNYAKTRLLKKEDKTALI 507
W++ V + L KI+ +V++ CL+ + +E+L Y LK D AL+
Sbjct: 561 WRKSAVNVASIQNYLSKIKKRSWVLHECLERVPENVDAAKELLQYG----LKGTDLEALL 616
>gi|157671917 hypothetical protein LOC374864 isoform 2 [Homo sapiens]
Length = 829
Score = 35.0 bits (79), Expect = 0.82
Identities = 84/388 (21%), Positives = 155/388 (39%), Gaps = 54/388 (13%)
Query: 673 LKDYQNTEEVCQLRTLVNNLRELITLHRKYNCKLALSDFEKENTTTIVFRMFDKVLAPEL 732
L D + +E+ L+ E++ LHRK N +L + EN R+ + + E+
Sbjct: 272 LLDSKQNQELQDLKNHYKKKMEVMDLHRKVNEELEEALEACENA-----RLKAQQIKEEI 326
Query: 733 IPSIL--EKFIRVYMREHDLQEEELLLLYIEDLLN---RCSSKSTSLFETAWEAKAM--- 784
I EK I Y RE Q L Y ++N K + E E K+
Sbjct: 327 DKDIYQDEKTIEAYKRE-IYQLNSLFDHYSSSVINVNTNIEEKEEEVTEAIRETKSSKNE 385
Query: 785 --AVIACLSDTDLIFDAV--------------LKIMYAAVVPWSAAVEQLVKQHLEMDHP 828
++ L D ++D + + YAA W + + K +
Sbjct: 386 LHSLSKMLEDLRRVYDQLTWKQKSHENQYLEAVNDFYAAKKTWDIELSDVAKDFSAISLA 445
Query: 829 KVKLLQESYKL-MEMKKLL--RGYGIREVNLLNKEIMRVVRYILKQD--VPSSLEDALKV 883
KL +++ KL +++ K+ IR+ + EI + LK D + + ++A ++
Sbjct: 446 CTKLTEDNKKLEIDINKITVKTNESIRKKSKYESEIKYLTIMKLKNDKHLKNIYKEAYRI 505
Query: 884 AQAFMLSDDEIYSL--RIIDLIDREQGEDCLLLLKSLPPAEAEKTAERVIIWARLALQEE 941
F L+ + + +I ++ + +G + LK L E + A + LQ++
Sbjct: 506 GTLFHLTKHKTDEMEDKIAEVRRKFKGRE--EFLKKLTQGE---------VAAGMVLQKK 554
Query: 942 PDHSKEGKAW-RMSVAKTSVDILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVF 1000
E +A R + K L ++Q+ LQ +DE E + L KE S+ + +F
Sbjct: 555 LYSIYEVQALERKELIKNRAICAMSLAELQEPLLQLEDEAERIRSLDKE-HSVSKRSAIF 613
Query: 1001 LSFEDYSNSSLV--ADLRE--QHIKAHE 1024
E + +++ A + E + +KA E
Sbjct: 614 KDLEATKSKTMIFYAKINELNEELKAKE 641
>gi|224586784 hypothetical protein LOC731220 [Homo sapiens]
Length = 473
Score = 34.3 bits (77), Expect = 1.4
Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 5/70 (7%)
Query: 1944 EGMIKGLWKNHSHESMAVRLVTELCLEYKIYDLQLWNG----LLQKLLGFNMIPYLRKVL 1999
E ++ WK+ +++ + + ++C +K YD+QL+ G LL L I YL+ V
Sbjct: 81 EDLLTSFWKSLQQDTVMLMSLPDVCQLFKCYDVQLYKGIEDVLLHDFLEDVSIQYLKSV- 139
Query: 2000 KAISSIHSLW 2009
+ S LW
Sbjct: 140 QLFSKKFKLW 149
>gi|157671919 hypothetical protein LOC374864 isoform 1 [Homo
sapiens]
Length = 867
Score = 33.9 bits (76), Expect = 1.8
Identities = 77/356 (21%), Positives = 140/356 (39%), Gaps = 49/356 (13%)
Query: 673 LKDYQNTEEVCQLRTLVNNLRELITLHRKYNCKLALSDFEKENTTTIVFRMFDKVLAPEL 732
L D + +E+ L+ E++ LHRK N +L + EN R+ + + E+
Sbjct: 272 LLDSKQNQELQDLKNHYKKKMEVMDLHRKVNEELEEALEACENA-----RLKAQQIKEEI 326
Query: 733 IPSIL--EKFIRVYMREHDLQEEELLLLYIEDLLN---RCSSKSTSLFETAWEAKAM--- 784
I EK I Y RE Q L Y ++N K + E E K+
Sbjct: 327 DKDIYQDEKTIEAYKRE-IYQLNSLFDHYSSSVINVNTNIEEKEEEVTEAIRETKSSKNE 385
Query: 785 --AVIACLSDTDLIFDAV--------------LKIMYAAVVPWSAAVEQLVKQHLEMDHP 828
++ L D ++D + + YAA W + + K +
Sbjct: 386 LHSLSKMLEDLRRVYDQLTWKQKSHENQYLEAVNDFYAAKKTWDIELSDVAKDFSAISLA 445
Query: 829 KVKLLQESYKL-MEMKKLL--RGYGIREVNLLNKEIMRVVRYILKQD--VPSSLEDALKV 883
KL +++ KL +++ K+ IR+ + EI + LK D + + ++A ++
Sbjct: 446 CTKLTEDNKKLEIDINKITVKTNESIRKKSKYESEIKYLTIMKLKNDKHLKNIYKEAYRI 505
Query: 884 AQAFMLSDDEIYSL--RIIDLIDREQGEDCLLLLKSLPPAEAEKTAERVIIWARLALQEE 941
F L+ + + +I ++ + +G + LK L E + A + LQ++
Sbjct: 506 GTLFHLTKHKTDEMEDKIAEVRRKFKGRE--EFLKKLTQGE---------VAAGMVLQKK 554
Query: 942 PDHSKEGKAW-RMSVAKTSVDILKILCDIQKDNLQKKDECEEMLKLFKEVASLQEN 996
E +A R + K L ++Q+ LQ +DE E + L KE + + N
Sbjct: 555 LYSIYEVQALERKELIKNRAICAMSLAELQEPLLQLEDEAERIRSLDKEHSVMLNN 610
>gi|156616301 kelch-like 32 [Homo sapiens]
Length = 620
Score = 33.5 bits (75), Expect = 2.4
Identities = 60/251 (23%), Positives = 98/251 (39%), Gaps = 50/251 (19%)
Query: 1081 KTALKKCSDLFKYHCNADTGKLLFLTCQKLCQMLADNVPVTVPVGLNLPSMIHDLASQAA 1140
K L CSD F+ +F C + + AD V + L L + + A
Sbjct: 57 KAVLAACSDYFR---------AMFSLC--MVESGADEVNLHGVTSLGLKQAL-EFAYTGQ 104
Query: 1141 TICSPDFLLDALELCKHTLMAVELSRQCQMDDCGILMKASFGTHKDPYEEWSYSDFFSED 1200
+ P + D L H L +EL C ++ + + + D Y +D F+
Sbjct: 105 ILLEPGVIQDVLAAGSH-LQLLELLNLCSHY---LIQELNSFNYLDLYR---LADLFN-- 155
Query: 1201 GIVLESQMVLPVIYELISSLVPLAESKRYPLESTSLPYCSLNEGDGLVLPVINSISALLQ 1260
+ L + V+ + + +S L+ K P E +LPYC L E VL S L
Sbjct: 156 -LTLLEKAVIDFLVKHLSELL-----KSRPEEVLTLPYCLLQE----VLK-----SDRLT 200
Query: 1261 NLQESSQWELALRFVVGSFGTCLQHSVS-NFMNATLSEKLFGETTL-----VKSRHVVME 1314
+L E W+LA+R+ L+H+ +M+ L FG + V H +++
Sbjct: 201 SLSEEQIWQLAVRW--------LEHNCHYQYMDELLQYIRFGLMDVDTLHTVALSHPLVQ 252
Query: 1315 LKEKAVIFIRE 1325
E A + E
Sbjct: 253 ASETATALVNE 263
>gi|161702986 ezrin [Homo sapiens]
Length = 586
Score = 32.7 bits (73), Expect = 4.1
Identities = 30/125 (24%), Positives = 63/125 (50%), Gaps = 6/125 (4%)
Query: 969 IQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSNSSLVAD--LREQHIKAHEVA 1026
+++ L+ + + E ++ KE ++E E+ L +DY + A+ L EQ +A ++
Sbjct: 318 LERQQLETEKKRRETVEREKE-QMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLE 376
Query: 1027 QAKHKPGSTPEPIAAEVRSPSMESK--LHRQALALQMSKQELEAELTLRALKDGNIKTAL 1084
+ + + E + A+ R ++ +K L RQA+ S+++L AEL K ++ A
Sbjct: 377 EERKRAQEEAERLEAD-RMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEAR 435
Query: 1085 KKCSD 1089
++ D
Sbjct: 436 RRKED 440
>gi|21614499 ezrin [Homo sapiens]
Length = 586
Score = 32.7 bits (73), Expect = 4.1
Identities = 30/125 (24%), Positives = 63/125 (50%), Gaps = 6/125 (4%)
Query: 969 IQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSNSSLVAD--LREQHIKAHEVA 1026
+++ L+ + + E ++ KE ++E E+ L +DY + A+ L EQ +A ++
Sbjct: 318 LERQQLETEKKRRETVEREKE-QMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLE 376
Query: 1027 QAKHKPGSTPEPIAAEVRSPSMESK--LHRQALALQMSKQELEAELTLRALKDGNIKTAL 1084
+ + + E + A+ R ++ +K L RQA+ S+++L AEL K ++ A
Sbjct: 377 EERKRAQEEAERLEAD-RMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEAR 435
Query: 1085 KKCSD 1089
++ D
Sbjct: 436 RRKED 440
>gi|217416374 hypothetical protein LOC92749 [Homo sapiens]
Length = 740
Score = 32.7 bits (73), Expect = 4.1
Identities = 45/222 (20%), Positives = 90/222 (40%), Gaps = 22/222 (9%)
Query: 444 DASEQTEWQQLVDDAKENLHKI--QDDEFVVNYCLKAQWITYETTQEMLNYAKTRLLKKE 501
D +Q Q++ D + N+ KI + D ++ L+ + Y+ QE L Y L K++
Sbjct: 268 DYEKQLNRQRIWDCEEYNMIKIKLEQDVQILEQQLQQRKAIYQLNQEKLEYNLQVLKKRD 327
Query: 502 DKTALIYSDGLKEVLRAHAKLTTFYGAFGPEKFSGSSWIEFLNNEDDLKDIFLQLKEGNL 561
+++ +I S +++ R H L + + + L + D K + +Q KE
Sbjct: 328 EESTVIKSQQKRKINRLHDILNNLRSKYAKQIKQFQEENQSLTS--DYKRLVMQFKELQK 385
Query: 562 VCAQY----------LWLRHRANFES----RFDVKMLESLLNSMSASVSLQKLCPWFKND 607
+ +WL + + FDV + ++++ + WF N+
Sbjct: 386 AMRHFALIDDEKFWEIWLMNEEEAKDLIARAFDV---DRIIHTHHLGLPWAAPDFWFLNN 442
Query: 608 VIPFVRRTVPEGQIILAKWLEQAARNLELTDKANWPENGLQL 649
V P ++ I+ + L ++ E + A PE+ L L
Sbjct: 443 VGPISQQPQKSATQIVEEMLMRSEEE-EAEEAAAEPESYLDL 483
>gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Homo
sapiens]
Length = 864
Score = 32.7 bits (73), Expect = 4.1
Identities = 49/247 (19%), Positives = 105/247 (42%), Gaps = 15/247 (6%)
Query: 830 VKLLQESYKL-MEMKKLLRGYGIREVNLLNKEIMRVVRYILKQDVPSSLEDALKVAQAFM 888
+K + + KL + ++LR + ++ + + E R RY L Q P+ + A A+
Sbjct: 100 IKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYH 159
Query: 889 LSDDEIYSLRIIDLIDREQGEDCLLLLKSLPPAEAEKTAERVIIWARLALQEEPDHSKEG 948
L D +L++++ + Q +PP + + +I++ ++ E D +E
Sbjct: 160 LLKDYDMALKLLEEFRQTQ---------QVPPNKIDYEYSELILYQNQVMR-EADLLQES 209
Query: 949 KAWRMSVAKTSVDILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSN 1008
K D L ++ +I+ + L K +E ++FK + + N E + +E
Sbjct: 210 LEHIEMYEKQICDKL-LVEEIKGEILLKLGRLKEASEVFKNL--IDRNAENWCYYEGLEK 266
Query: 1009 SSLVADLREQHIKAHEVAQAKHKPGSTPEPIAAEVRSPSMESKLHRQALALQMSKQELEA 1068
+ ++ L E+ ++ +E +H TP + + +L + L + SK
Sbjct: 267 ALQISTL-EERLQIYEEISKQHPKAITPRRLPLTLVPGERFRELMDKFLRVNFSKGCPPL 325
Query: 1069 ELTLRAL 1075
TL++L
Sbjct: 326 FTTLKSL 332
>gi|160707985 NMDA receptor regulated 1-like protein isoform 3 [Homo
sapiens]
Length = 429
Score = 32.7 bits (73), Expect = 4.1
Identities = 49/247 (19%), Positives = 105/247 (42%), Gaps = 15/247 (6%)
Query: 830 VKLLQESYKL-MEMKKLLRGYGIREVNLLNKEIMRVVRYILKQDVPSSLEDALKVAQAFM 888
+K + + KL + ++LR + ++ + + E R RY L Q P+ + A A+
Sbjct: 100 IKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYH 159
Query: 889 LSDDEIYSLRIIDLIDREQGEDCLLLLKSLPPAEAEKTAERVIIWARLALQEEPDHSKEG 948
L D +L++++ + Q +PP + + +I++ ++ E D +E
Sbjct: 160 LLKDYDMALKLLEEFRQTQ---------QVPPNKIDYEYSELILYQNQVMR-EADLLQES 209
Query: 949 KAWRMSVAKTSVDILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSN 1008
K D L ++ +I+ + L K +E ++FK + + N E + +E
Sbjct: 210 LEHIEMYEKQICDKL-LVEEIKGEILLKLGRLKEASEVFKNL--IDRNAENWCYYEGLEK 266
Query: 1009 SSLVADLREQHIKAHEVAQAKHKPGSTPEPIAAEVRSPSMESKLHRQALALQMSKQELEA 1068
+ ++ L E+ ++ +E +H TP + + +L + L + SK
Sbjct: 267 ALQISTL-EERLQIYEEISKQHPKAITPRRLPLTLVPGERFRELMDKFLRVNFSKGCPPL 325
Query: 1069 ELTLRAL 1075
TL++L
Sbjct: 326 FTTLKSL 332
>gi|157389009 hypothetical protein LOC144608 [Homo sapiens]
Length = 245
Score = 32.7 bits (73), Expect = 4.1
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 23/127 (18%)
Query: 921 AEAEKTAERVIIWARLALQEEPDHSKEGKAWRMSVAKTSVDIL------KILCDIQKDNL 974
+E+EK ER+I A++ D + SV T ++ +IL K+N
Sbjct: 3 SESEKDKERLIQAAKMFFFHVQDLA--------SVINTLTELFSRSMNTQILLMAVKNNS 54
Query: 975 QKKDECEEMLKLFKEVASLQENFEVFLSFEDYSNSSLVA---------DLREQHIKAHEV 1025
KD E+MLK+FKE+ S+ + + E + +A ++ E H A EV
Sbjct: 55 YIKDFFEQMLKIFKEMQSVVDARHDKIQKESLCSKVAMAMCSVVQKSTNVEELHQSAKEV 114
Query: 1026 AQAKHKP 1032
++ H P
Sbjct: 115 FKSAHTP 121
>gi|93102364 SWAP-70 protein [Homo sapiens]
Length = 585
Score = 32.3 bits (72), Expect = 5.3
Identities = 51/244 (20%), Positives = 105/244 (43%), Gaps = 23/244 (9%)
Query: 867 YILKQDVPSS-LEDALKVAQAFMLSDDEIYSLRIIDLIDREQGEDCLLLLKSLPP----A 921
++LK ++ S + + LK + +L D+ ++ + + G+ CL L+K +
Sbjct: 232 FVLKPNIISYYVSEDLKDKKGDILLDENC----CVESLPDKDGKKCLFLVKCFDKTFEIS 287
Query: 922 EAEKTAERVIIWA------RLALQEEPDHSKEGKAWRMSVAKTSV----DILKILCDIQK 971
++K ++ I A L L P H KE + R + K + ++ + + ++Q
Sbjct: 288 ASDKKKKQEWIQAIHSTIHLLKLGSPPPH-KEARQRRKELRKKQLAEQEELERQMKELQA 346
Query: 972 DNLQKKDECEEMLKLFKEVAS-LQENFEVFLSFEDYSNSSLVADLREQHIKAHEVAQAKH 1030
N K+ E E + K +E AS E + L + + +L + + ++ +
Sbjct: 347 ANESKQQELEAVRKKLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVA 406
Query: 1031 KPGSTPEPIAAEVRSPSMESKLHRQALALQMSKQELEAELTLRALKDGNIKTALKKCSDL 1090
+ S E VR +E + AL+ +Q + E T+R L+ ++ K ++L
Sbjct: 407 QKSSELEQYLQRVRE--LEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAEL 464
Query: 1091 FKYH 1094
K+H
Sbjct: 465 EKWH 468
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 32.3 bits (72), Expect = 5.3
Identities = 20/50 (40%), Positives = 26/50 (52%)
Query: 994 QENFEVFLSFEDYSNSSLVADLREQHIKAHEVAQAKHKPGSTPEPIAAEV 1043
+E F+ F S ED + SSL + LR Q +A KHK P P A+V
Sbjct: 120 EEEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADV 169
>gi|27734829 hypothetical protein LOC256329 [Homo sapiens]
Length = 634
Score = 32.3 bits (72), Expect = 5.3
Identities = 38/139 (27%), Positives = 61/139 (43%), Gaps = 29/139 (20%)
Query: 371 VCKNDPKLSEDSVSVLVLRCLTEALPENRLSRLLHKHRFAEAES--FAIQFGLDVELVYK 428
VC DP+L+ +S+ + R RLL + R E ++ +AIQ G D L
Sbjct: 47 VCSADPQLALESL-------------DPRTLRLLWRQRELEIQALRWAIQNGEDARLC-- 91
Query: 429 VKSNHILEKLA-------LSSVDASEQTEWQQLVDDAKENLHKIQ-DDEFVVNYCLKAQW 480
HILE++A S + Q + Q+L+ + KE + Q + E + L+
Sbjct: 92 ----HILEEVAGLPPKRSSHSQEKLLQNQVQKLIQELKEQKERAQWEKEHLEERLLQTTR 147
Query: 481 ITYETTQEMLNYAKTRLLK 499
E E+ N K+ LL+
Sbjct: 148 TLQEMEAELQNLQKSCLLQ 166
>gi|41152093 zinc finger protein 644 isoform 1 [Homo sapiens]
Length = 1327
Score = 32.3 bits (72), Expect = 5.3
Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 1/74 (1%)
Query: 1776 LYEHPSINQRIQNSSGTDYPDIHAAAKEIAEVNEINLEKVWDMLLEKWLCPSTKPGEKPS 1835
LY H N R+ SG YP +H +E + +N ++L ++ KP K
Sbjct: 739 LYRHKYENYRMIKKSGESYP-VHFKKEEASSLNSLHLFSSSSNSHNNFISDPHKPDAKRP 797
Query: 1836 ELFELQEDEALRRV 1849
E F+ A++RV
Sbjct: 798 ESFKDHRRVAVKRV 811
>gi|33356130 NMDA receptor regulated 1-like protein isoform 2 [Homo
sapiens]
Length = 311
Score = 32.3 bits (72), Expect = 5.3
Identities = 42/208 (20%), Positives = 91/208 (43%), Gaps = 15/208 (7%)
Query: 830 VKLLQESYKL-MEMKKLLRGYGIREVNLLNKEIMRVVRYILKQDVPSSLEDALKVAQAFM 888
+K + + KL + ++LR + ++ + + E R RY L Q P+ + A A+
Sbjct: 100 IKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYH 159
Query: 889 LSDDEIYSLRIIDLIDREQGEDCLLLLKSLPPAEAEKTAERVIIWARLALQEEPDHSKEG 948
L D +L++++ + Q +PP + + +I++ ++ E D +E
Sbjct: 160 LLKDYDMALKLLEEFRQTQ---------QVPPNKIDYEYSELILYQNQVMR-EADLLQES 209
Query: 949 KAWRMSVAKTSVDILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSN 1008
K D L ++ +I+ + L K +E ++FK + + N E + +E
Sbjct: 210 LEHIEMYEKQICDKL-LVEEIKGEILLKLGRLKEASEVFKNL--IDRNAENWCYYEGLEK 266
Query: 1009 SSLVADLREQHIKAHEVAQAKHKPGSTP 1036
+ ++ L E+ ++ +E +H TP
Sbjct: 267 ALQISTL-EERLQIYEEISKQHPKAITP 293
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 32.0 bits (71), Expect = 6.9
Identities = 46/195 (23%), Positives = 87/195 (44%), Gaps = 33/195 (16%)
Query: 1359 ENLWKLIDKAWQNYDKILAISLVGSELASLYQEIEMGLKFRELSTDAQWGIRLGKLGISF 1418
+N+ K+ ++ + Y + I + SEL+ E+ + LK R+ D + K +
Sbjct: 5301 QNIEKMAEEQKEKYLGLYTI--LPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKA--TS 5356
Query: 1419 QPVFRQHFLTKKDL------IKALVENI---DMDTSLI---LEYCSTFQLDCDAVLQLFI 1466
Q + RQ KDL +KA +N+ D ++ L+ C++ ++ DA +Q F+
Sbjct: 5357 QELSRQIQKLAKDLTTILTKLKAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFL 5416
Query: 1467 ETLLHNTNAGQGQGDASMDSAKRRHPKLLAKALEM-VPLLTSTKDLVISLSGILHKLDPY 1525
E G AK+ + K E+ + ++ + L+ L+ Y
Sbjct: 5417 EQ----------NGQLGKPLAKK-----IGKLTELHQQTIRQAENRLSKLNQAASHLEEY 5461
Query: 1526 DYEMIEVVLKVIERA 1540
+ EM+E++LK IE+A
Sbjct: 5462 N-EMLELILKWIEKA 5475
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,629,534
Number of Sequences: 37866
Number of extensions: 3207902
Number of successful extensions: 9145
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 9065
Number of HSP's gapped (non-prelim): 134
length of query: 2209
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2091
effective length of database: 13,779,330
effective search space: 28812579030
effective search space used: 28812579030
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.