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Search of human proteins with 7661860
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7661860 leucine rich repeat containing 14 [Homo sapiens]
(493 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7661860 leucine rich repeat containing 14 [Homo sapiens] 979 0.0
gi|122937351 hypothetical protein LOC389257 [Homo sapiens] 206 5e-53
gi|46249373 preferentially expressed antigen in melanoma [Homo s... 185 7e-47
gi|46249371 preferentially expressed antigen in melanoma [Homo s... 185 7e-47
gi|46249369 preferentially expressed antigen in melanoma [Homo s... 185 7e-47
gi|46249367 preferentially expressed antigen in melanoma [Homo s... 185 7e-47
gi|5174641 preferentially expressed antigen in melanoma [Homo sa... 185 7e-47
gi|58219004 PRAME family member 6 [Homo sapiens] 177 2e-44
gi|61696142 PRAME family member 5 [Homo sapiens] 175 7e-44
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens] 172 8e-43
gi|59958373 PRAME family member 4 [Homo sapiens] 171 1e-42
gi|169216010 PREDICTED: preferentially expressed antigen in mela... 171 1e-42
gi|169215813 PREDICTED: preferentially expressed antigen in mela... 171 1e-42
gi|148356236 PRAME family member 15 [Homo sapiens] 171 2e-42
gi|61102721 PRAME family member 9 [Homo sapiens] 171 2e-42
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens] 169 5e-42
gi|239746677 PREDICTED: preferentially expressed antigen in mela... 169 7e-42
gi|153792112 PRAME family member 20 [Homo sapiens] 166 6e-41
gi|153945800 PRAME family member 21 [Homo sapiens] 166 6e-41
gi|59676593 PRAME family member 7 [Homo sapiens] 164 1e-40
gi|239741053 PREDICTED: similar to Putative PRAME family member ... 164 1e-40
gi|59676587 PRAME family member 8 [Homo sapiens] 164 2e-40
gi|124249372 PRAME family member 12 [Homo sapiens] 159 7e-39
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens] 152 9e-37
gi|226437621 PRAME family member 11 [Homo sapiens] 149 7e-36
gi|88942379 PREDICTED: PRAME family member [Homo sapiens] 139 8e-33
gi|153791443 PRAME family member 18 [Homo sapiens] 123 4e-28
gi|194306638 PRAME family member 3 [Homo sapiens] 122 7e-28
gi|154800493 PRAME family member 22 [Homo sapiens] 119 5e-27
gi|194306635 PRAME family member 19 [Homo sapiens] 119 5e-27
>gi|7661860 leucine rich repeat containing 14 [Homo sapiens]
Length = 493
Score = 979 bits (2531), Expect = 0.0
Identities = 493/493 (100%), Positives = 493/493 (100%)
Query: 1 MHTLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLS 60
MHTLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLS
Sbjct: 1 MHTLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLS 60
Query: 61 FQQLLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMT 120
FQQLLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMT
Sbjct: 61 FQQLLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMT 120
Query: 121 GLLDDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVNRASYAF 180
GLLDDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVNRASYAF
Sbjct: 121 GLLDDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVNRASYAF 180
Query: 181 LREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGLRGLSVI 240
LREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGLRGLSVI
Sbjct: 181 LREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGLRGLSVI 240
Query: 241 IPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMGSSLLSGRL 300
IPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMGSSLLSGRL
Sbjct: 241 IPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMGSSLLSGRL 300
Query: 301 DQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQLAPFQGLL 360
DQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQLAPFQGLL
Sbjct: 301 DQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQLAPFQGLL 360
Query: 361 QASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKELLRDSVAQ 420
QASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKELLRDSVAQ
Sbjct: 361 QASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKELLRDSVAQ 420
Query: 421 AELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLLASGRAHVLWTT 480
AELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLLASGRAHVLWTT
Sbjct: 421 AELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLLASGRAHVLWTT 480
Query: 481 DIYGRLAADYFSL 493
DIYGRLAADYFSL
Sbjct: 481 DIYGRLAADYFSL 493
>gi|122937351 hypothetical protein LOC389257 [Homo sapiens]
Length = 514
Score = 206 bits (523), Expect = 5e-53
Identities = 160/497 (32%), Positives = 245/497 (49%), Gaps = 25/497 (5%)
Query: 1 MHTLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLS 60
M +L F+S ++ A Q+L + L+PLLFK +++ ++ V R ++ WP
Sbjct: 4 MRSLRFISAEALVSHPQVARQSLDSVAHNLYPLLFKASYLLEQAEVTRAVLGRWPLEEFR 63
Query: 61 FQQLLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMT 120
LL A + L ++R ++A++ GL + + LRV D+T
Sbjct: 64 LGALLGPGADHPQDL-RDRTCRACLEALVRGLADHVLQDRS---------RRRLRVADLT 113
Query: 121 GLLDDGVEQDP--GTMSMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVNRASY 178
G+ D V++ P + W T +ARTC Q AEP A PVEV DL V ++
Sbjct: 114 GIRDVQVQRCPCGRALGRWGRTQLLARTCCELQ----AEPLAAGRPVEVLADLFVTEGNF 169
Query: 179 AFLREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFN-NLGLRGL 237
+ +ALR + +PLR+ C RA+ L + +L+L G LR++++ N L +
Sbjct: 170 EAVVQALRPAGPAPLRVHCPSFRADSLSPSQLLHVLRLAGPGALRKLEVVHNVRLHAGHV 229
Query: 238 SVIIPHVARFQHLASLRLHYVHGDSRQP---SVDGEDNFRYFLA-QMGRFTCLRELSMGS 293
++ V F LASL L D+ + DGED +A ++ + L ELS+
Sbjct: 230 QQLLAQVG-FPRLASLTLPTKAFDAPPTYASTPDGEDPLLASIARELSKMAQLTELSVAF 288
Query: 294 SLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQL 353
S L+G++ LL LQ+PL L+LA CAL D+ FLA HAAHL+ LDLSG++L
Sbjct: 289 STLTGKIPTLLGPLQTPLRVLDLANCALNHTDMAFLADCAHAAHLEVLDLSGHNLVSLYP 348
Query: 354 APFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKEL 413
+ F LL ++ TL L L EC + D+ + + L+ C LR L GNPLS L+ L
Sbjct: 349 STFFRLLSQASRTLRILTLEECGIVDSHVGMLILGLSPCHRLRQLKFLGNPLSARALRRL 408
Query: 414 LRDSVAQAELRTVVHPFPVDCY-EGLPWPPPASVLLEASINEEKFARVEAELHQLLLASG 472
ELR + P P DCY EG + P L + N++K+ + EL +LL +
Sbjct: 409 FTALCELPELRCIEFPVPKDCYPEGAAY--PQDELAMSKFNQQKYDEIAEELRAVLLRAD 466
Query: 473 RAHVLWTTDIYGRLAAD 489
R + +T ++G D
Sbjct: 467 REDIQVSTPLFGSFDPD 483
>gi|46249373 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 185 bits (470), Expect = 7e-47
Identities = 149/489 (30%), Positives = 237/489 (48%), Gaps = 47/489 (9%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
LV L+ + +L+ + A AL LLPRELFP LF AF + + L+ +V WPF L
Sbjct: 26 LVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCLPLGV 85
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ + E+ +AV+ GL L +P R+ L+VLD L
Sbjct: 86 LMKG----------QHLHLETFKAVLDGLDVLL-----AQEVRP--RRWKLQVLD----L 124
Query: 124 DDGVEQDPGTM---------SMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVN 174
QD T+ S + AA T + G + E IPVEV VDL +
Sbjct: 125 RKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLK 184
Query: 175 RAS----YAFLREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFN 230
+ +++L E ++ + LRLCC+ L+ +PM++ +L+++ + +++
Sbjct: 185 EGACDELFSYLIEKVKRKK-NVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCT 243
Query: 231 NLGLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELS 290
L L+ P++ + +L L L ++H S E F +Q CL+ L
Sbjct: 244 -WKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALY 302
Query: 291 MGSSL-LSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLS 349
+ S L GRLDQLL + +PLE+L + C L D+ L++SP + L L LSG L+
Sbjct: 303 VDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLT 362
Query: 350 GSQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAG 409
P Q LL+ ++ATL L EC + D QLLA LP L+ C+ L L YGN +S++
Sbjct: 363 DVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISA 422
Query: 410 LKELLRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLL 469
L+ LL+ + + L V++P P++ YE + +++ E+ A + A L +LL
Sbjct: 423 LQSLLQHLIGLSNLTHVLYPVPLESYED----------IHGTLHLERLAYLHARLRELLC 472
Query: 470 ASGRAHVLW 478
GR ++W
Sbjct: 473 ELGRPSMVW 481
>gi|46249371 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 185 bits (470), Expect = 7e-47
Identities = 149/489 (30%), Positives = 237/489 (48%), Gaps = 47/489 (9%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
LV L+ + +L+ + A AL LLPRELFP LF AF + + L+ +V WPF L
Sbjct: 26 LVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCLPLGV 85
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ + E+ +AV+ GL L +P R+ L+VLD L
Sbjct: 86 LMKG----------QHLHLETFKAVLDGLDVLL-----AQEVRP--RRWKLQVLD----L 124
Query: 124 DDGVEQDPGTM---------SMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVN 174
QD T+ S + AA T + G + E IPVEV VDL +
Sbjct: 125 RKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLK 184
Query: 175 RAS----YAFLREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFN 230
+ +++L E ++ + LRLCC+ L+ +PM++ +L+++ + +++
Sbjct: 185 EGACDELFSYLIEKVKRKK-NVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCT 243
Query: 231 NLGLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELS 290
L L+ P++ + +L L L ++H S E F +Q CL+ L
Sbjct: 244 -WKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALY 302
Query: 291 MGSSL-LSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLS 349
+ S L GRLDQLL + +PLE+L + C L D+ L++SP + L L LSG L+
Sbjct: 303 VDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLT 362
Query: 350 GSQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAG 409
P Q LL+ ++ATL L EC + D QLLA LP L+ C+ L L YGN +S++
Sbjct: 363 DVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISA 422
Query: 410 LKELLRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLL 469
L+ LL+ + + L V++P P++ YE + +++ E+ A + A L +LL
Sbjct: 423 LQSLLQHLIGLSNLTHVLYPVPLESYED----------IHGTLHLERLAYLHARLRELLC 472
Query: 470 ASGRAHVLW 478
GR ++W
Sbjct: 473 ELGRPSMVW 481
>gi|46249369 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 185 bits (470), Expect = 7e-47
Identities = 149/489 (30%), Positives = 237/489 (48%), Gaps = 47/489 (9%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
LV L+ + +L+ + A AL LLPRELFP LF AF + + L+ +V WPF L
Sbjct: 26 LVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCLPLGV 85
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ + E+ +AV+ GL L +P R+ L+VLD L
Sbjct: 86 LMKG----------QHLHLETFKAVLDGLDVLL-----AQEVRP--RRWKLQVLD----L 124
Query: 124 DDGVEQDPGTM---------SMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVN 174
QD T+ S + AA T + G + E IPVEV VDL +
Sbjct: 125 RKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLK 184
Query: 175 RAS----YAFLREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFN 230
+ +++L E ++ + LRLCC+ L+ +PM++ +L+++ + +++
Sbjct: 185 EGACDELFSYLIEKVKRKK-NVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCT 243
Query: 231 NLGLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELS 290
L L+ P++ + +L L L ++H S E F +Q CL+ L
Sbjct: 244 -WKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALY 302
Query: 291 MGSSL-LSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLS 349
+ S L GRLDQLL + +PLE+L + C L D+ L++SP + L L LSG L+
Sbjct: 303 VDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLT 362
Query: 350 GSQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAG 409
P Q LL+ ++ATL L EC + D QLLA LP L+ C+ L L YGN +S++
Sbjct: 363 DVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISA 422
Query: 410 LKELLRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLL 469
L+ LL+ + + L V++P P++ YE + +++ E+ A + A L +LL
Sbjct: 423 LQSLLQHLIGLSNLTHVLYPVPLESYED----------IHGTLHLERLAYLHARLRELLC 472
Query: 470 ASGRAHVLW 478
GR ++W
Sbjct: 473 ELGRPSMVW 481
>gi|46249367 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 185 bits (470), Expect = 7e-47
Identities = 149/489 (30%), Positives = 237/489 (48%), Gaps = 47/489 (9%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
LV L+ + +L+ + A AL LLPRELFP LF AF + + L+ +V WPF L
Sbjct: 26 LVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCLPLGV 85
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ + E+ +AV+ GL L +P R+ L+VLD L
Sbjct: 86 LMKG----------QHLHLETFKAVLDGLDVLL-----AQEVRP--RRWKLQVLD----L 124
Query: 124 DDGVEQDPGTM---------SMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVN 174
QD T+ S + AA T + G + E IPVEV VDL +
Sbjct: 125 RKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLK 184
Query: 175 RAS----YAFLREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFN 230
+ +++L E ++ + LRLCC+ L+ +PM++ +L+++ + +++
Sbjct: 185 EGACDELFSYLIEKVKRKK-NVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCT 243
Query: 231 NLGLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELS 290
L L+ P++ + +L L L ++H S E F +Q CL+ L
Sbjct: 244 -WKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALY 302
Query: 291 MGSSL-LSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLS 349
+ S L GRLDQLL + +PLE+L + C L D+ L++SP + L L LSG L+
Sbjct: 303 VDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLT 362
Query: 350 GSQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAG 409
P Q LL+ ++ATL L EC + D QLLA LP L+ C+ L L YGN +S++
Sbjct: 363 DVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISA 422
Query: 410 LKELLRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLL 469
L+ LL+ + + L V++P P++ YE + +++ E+ A + A L +LL
Sbjct: 423 LQSLLQHLIGLSNLTHVLYPVPLESYED----------IHGTLHLERLAYLHARLRELLC 472
Query: 470 ASGRAHVLW 478
GR ++W
Sbjct: 473 ELGRPSMVW 481
>gi|5174641 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 185 bits (470), Expect = 7e-47
Identities = 149/489 (30%), Positives = 237/489 (48%), Gaps = 47/489 (9%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
LV L+ + +L+ + A AL LLPRELFP LF AF + + L+ +V WPF L
Sbjct: 26 LVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCLPLGV 85
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ + E+ +AV+ GL L +P R+ L+VLD L
Sbjct: 86 LMKG----------QHLHLETFKAVLDGLDVLL-----AQEVRP--RRWKLQVLD----L 124
Query: 124 DDGVEQDPGTM---------SMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVN 174
QD T+ S + AA T + G + E IPVEV VDL +
Sbjct: 125 RKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLK 184
Query: 175 RAS----YAFLREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFN 230
+ +++L E ++ + LRLCC+ L+ +PM++ +L+++ + +++
Sbjct: 185 EGACDELFSYLIEKVKRKK-NVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCT 243
Query: 231 NLGLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELS 290
L L+ P++ + +L L L ++H S E F +Q CL+ L
Sbjct: 244 -WKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALY 302
Query: 291 MGSSL-LSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLS 349
+ S L GRLDQLL + +PLE+L + C L D+ L++SP + L L LSG L+
Sbjct: 303 VDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLT 362
Query: 350 GSQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAG 409
P Q LL+ ++ATL L EC + D QLLA LP L+ C+ L L YGN +S++
Sbjct: 363 DVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISA 422
Query: 410 LKELLRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLL 469
L+ LL+ + + L V++P P++ YE + +++ E+ A + A L +LL
Sbjct: 423 LQSLLQHLIGLSNLTHVLYPVPLESYED----------IHGTLHLERLAYLHARLRELLC 472
Query: 470 ASGRAHVLW 478
GR ++W
Sbjct: 473 ELGRPSMVW 481
>gi|58219004 PRAME family member 6 [Homo sapiens]
Length = 476
Score = 177 bits (449), Expect = 2e-44
Identities = 143/471 (30%), Positives = 228/471 (48%), Gaps = 51/471 (10%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L+ R +L+ Q A L LP ELFP LF AF ++ L+ +V WPF L +
Sbjct: 9 LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRP 68
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ P E+ QAV+ GL A L P R+ L+VLD+ +
Sbjct: 69 LIK------------MPCLEAFQAVLDGLDALLTQG-----VHP--RRWKLQVLDLQDVC 109
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEP-------GPAPIPVEVRVDLRVNRA 176
++ +W + A+AR C + G P+ V V + L+ NR
Sbjct: 110 EN-------FWMVW--SEAMARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLK-NRT 159
Query: 177 SYAFLREALR--SSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGL 234
+L L L LCC+ L+ +P RN ++L++++ C++ V++ + L
Sbjct: 160 LDEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWV-L 218
Query: 235 RGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMGS- 293
L+ P++ ++L L L ++ ++ F Q + CL++LSM S
Sbjct: 219 PILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSV 278
Query: 294 SLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQL 353
S L G LDQLLS L++ L+ L + C LL DL+ L++ P + LK LDLSG L+ L
Sbjct: 279 SFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSL 338
Query: 354 APFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKEL 413
P Q LL+ AATL +L+L +C + D+Q+ A LP L++C L GNP+SMA L+ L
Sbjct: 339 VPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENL 398
Query: 414 LRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAEL 464
L ++ L ++P P + Y+ + ++ +FA++ AEL
Sbjct: 399 LSHTIILKNLCVELYPAPRESYDA-----------DGTLCWSRFAQIRAEL 438
>gi|61696142 PRAME family member 5 [Homo sapiens]
Length = 476
Score = 175 bits (444), Expect = 7e-44
Identities = 143/471 (30%), Positives = 227/471 (48%), Gaps = 51/471 (10%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L+ R +L+ Q A L LP ELFP LF AF ++ L+ +V WPF L +
Sbjct: 9 LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRP 68
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ P E+ QAV+ GL A L P R+ L+VLD+ +
Sbjct: 69 LIK------------MPCLEAFQAVLDGLDALLTQG-----VHP--RRWKLQVLDLQDVC 109
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCIAQQ-------QGGAAEPGPAPIPVEVRVDLRVNRA 176
++ +W + A+A C Q G P+ V V + L+ NR
Sbjct: 110 EN-------FWMVW--SEAMAHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLK-NRT 159
Query: 177 SYAFLREALR--SSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGL 234
+L L L LCC+ L+ +P RN ++L++++ C++ V++ + L
Sbjct: 160 LDEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWV-L 218
Query: 235 RGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMGS- 293
L+ P++ ++L L L ++ ++ F Q + CL++LSM S
Sbjct: 219 PILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSV 278
Query: 294 SLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQL 353
S L G LDQLLS L++ L+ L + C LL DL+ L++ P + LK LDLSG L+ L
Sbjct: 279 SFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSL 338
Query: 354 APFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKEL 413
P Q LL+ AATL +L+L +C + D+Q+ A LP L++C L GNP+SMA L+ L
Sbjct: 339 VPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENL 398
Query: 414 LRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAEL 464
L ++ L ++P P + Y+ + ++ +FA++ AEL
Sbjct: 399 LSHTIILKNLCVELYPAPRESYDA-----------DGTLCWSRFAQIRAEL 438
>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
Length = 476
Score = 172 bits (435), Expect = 8e-43
Identities = 142/471 (30%), Positives = 225/471 (47%), Gaps = 51/471 (10%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L+ R +L+ Q A L LP ELFP LF AF ++ L+ +V WPF L +
Sbjct: 9 LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRP 68
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ P E+ QAV+ GL A L P R+ L+VLD+ +
Sbjct: 69 LIK------------MPCLEAFQAVLDGLDALLTQG-----VHP--RRWKLQVLDLQDVC 109
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCIAQQ-------QGGAAEPGPAPIPVEVRVDLRVNRA 176
++ +W + A+A C Q G P+ V V + L+ NR
Sbjct: 110 EN-------FWMVW--SEAMAHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLK-NRT 159
Query: 177 SYAFLREALR--SSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGL 234
+L L L LCC+ L+ +P RN ++L++++ C++ V++ + L
Sbjct: 160 LDEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWV-L 218
Query: 235 RGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMGS- 293
L+ P++ ++L L L ++ ++ F Q + CL++LSM S
Sbjct: 219 PILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSV 278
Query: 294 SLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQL 353
S L G LDQLLS L++ L+ L + C LL DL+ L++ P + LK LDLSG L+ L
Sbjct: 279 SFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSL 338
Query: 354 APFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKEL 413
P Q LL+ AATL +L+L +C + D+Q+ A LP L+ C L GNP+SMA L+ L
Sbjct: 339 VPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENL 398
Query: 414 LRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAEL 464
L ++ L ++P P + Y+ + ++ +F ++ AEL
Sbjct: 399 LSHTIILKNLCVELYPAPRESYDA-----------DGTLCWSRFPQIRAEL 438
>gi|59958373 PRAME family member 4 [Homo sapiens]
Length = 478
Score = 171 bits (434), Expect = 1e-42
Identities = 142/471 (30%), Positives = 230/471 (48%), Gaps = 51/471 (10%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L+ R +L+ Q A L LP ELFP LF AF ++ L+ +V +WPF L +
Sbjct: 11 LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWPFRRLPLRP 70
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ P E+ QAV+ GL A L+ +P R+ L+VLD+ +
Sbjct: 71 LIK------------MPCLEAFQAVLDGLDALLNLG-----VRP--RRWKLQVLDLQDVC 111
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCI--AQQQGGAAEPGPA-----PIPVEVRVDLRVNRA 176
++ +W + A+A C A++ E P P+ V V + L+ NR
Sbjct: 112 EN-------FWMVW--SEAMAHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLK-NRT 161
Query: 177 SYAFLREALR--SSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGL 234
+L L L LCC+ L+ +P RN ++L++++ C++ V++ + L
Sbjct: 162 LDEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWV-L 220
Query: 235 RGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMGS- 293
L+ P++ ++L L L ++ ++ F Q + CL++L M S
Sbjct: 221 PILTQFTPYLGHMRNLQKLILSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSV 280
Query: 294 SLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQL 353
S L G LDQLLS L++ L+ L + C LL DL+ L++ P + LK LDLSG L+ L
Sbjct: 281 SFLEGHLDQLLSCLKTSLKFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSL 340
Query: 354 APFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKEL 413
P Q LL+ AATL +L+L +C + D+Q+ A LP L++C L GNP+ MA L+ L
Sbjct: 341 VPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENL 400
Query: 414 LRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAEL 464
L ++ L ++P P + Y + ++ +FA++ AEL
Sbjct: 401 LSHTIILKNLCVELYPAPRESYGA-----------DGTLCWSRFAQIRAEL 440
>gi|169216010 PREDICTED: preferentially expressed antigen in
melanoma-like [Homo sapiens]
Length = 520
Score = 171 bits (433), Expect = 1e-42
Identities = 157/497 (31%), Positives = 222/497 (44%), Gaps = 77/497 (15%)
Query: 3 TLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQ 62
+L+ L+ +L + + L L LFP L AF L+ LV WPF L
Sbjct: 69 SLLELAAHSLLSNEASVPLVLEQLTVNLFPPLLTAAFAKGHRKALKALVQAWPFRFLHLG 128
Query: 63 QLLQECAHCSRALLQERPSTESMQAVILGLTA-RLHTSEPGASTQPLCRKHALRVLDMTG 121
L+ + P+ +S+QAV+ GL A H + P RK LR+LD T
Sbjct: 129 SLIVQW-----------PNQDSLQAVVDGLEAFSAHRACP--------RKSELRMLDFT- 168
Query: 122 LLDD--------GVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRV 173
LD G + W +A A T A A P P
Sbjct: 169 -LDSEQVFYCGKGASEALAKFPFWLPSAVKAETPQA-----TARPKPLD----------- 211
Query: 174 NRASYAFLREALRSSVGS--PLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDL---- 227
FL + L S L LCCR L E + + + + +L+ L ++ +++
Sbjct: 212 -----KFLSDLLTKVEQSHGALHLCCRKLHIEKMAVDSLLRILKTLRLDFIQELEVFYWC 266
Query: 228 -RFNNLGLRGLSVIIPHVARFQHLASLRLHYVHGDS----RQPSVDGEDNFRYFLAQMGR 282
F L LS I + R +L SL+L Y R+PS YF +Q+
Sbjct: 267 RDFLVLAEPNLSAI--QLGRIFNLRSLKLFYYKWAFSSWVRRPS-------SYFFSQLTM 317
Query: 283 FTCLRELSMGSSLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLD 342
LR+L + S L G+L +LS L PL SLE+ C LL D+ +L+RS H LKKLD
Sbjct: 318 LGHLRKLHLSHSYLVGKLHYILSCLWVPLHSLEICNCKLLDTDITYLSRSHHTTCLKKLD 377
Query: 343 LSGNDLSGSQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYG 402
LS NDLS P LL+A + TL HL+L C L D L A LP L +C+ L L L
Sbjct: 378 LSVNDLSYMIPGPLGTLLRAVSGTLQHLDLKHCWLKDAHLSALLPALCRCSHLSSLSLSD 437
Query: 403 NPLSMAGLKELLRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEA 462
NP+S A L LL ++ EL+ V++P PVDC L + +NE+K +++A
Sbjct: 438 NPISSACLLSLLEHTMGLMELKQVLYPIPVDCCIYL------HGVCRGPVNEDKLCQLQA 491
Query: 463 ELHQLLLASGRAHVLWT 479
E+ + L A +A + W+
Sbjct: 492 EIQKQLQAMQQADMQWS 508
>gi|169215813 PREDICTED: preferentially expressed antigen in
melanoma-like [Homo sapiens]
Length = 520
Score = 171 bits (433), Expect = 1e-42
Identities = 157/497 (31%), Positives = 222/497 (44%), Gaps = 77/497 (15%)
Query: 3 TLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQ 62
+L+ L+ +L + + L L LFP L AF L+ LV WPF L
Sbjct: 69 SLLELAAHSLLSNEASVPLVLEQLTVNLFPPLLTAAFAKGHRKALKALVQAWPFRFLHLG 128
Query: 63 QLLQECAHCSRALLQERPSTESMQAVILGLTA-RLHTSEPGASTQPLCRKHALRVLDMTG 121
L+ + P+ +S+QAV+ GL A H + P RK LR+LD T
Sbjct: 129 SLIVQW-----------PNQDSLQAVVDGLEAFSAHRACP--------RKSELRMLDFT- 168
Query: 122 LLDD--------GVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRV 173
LD G + W +A A T A A P P
Sbjct: 169 -LDSEQVFYCGKGASEALAKFPFWLPSAVKAETPQA-----TARPKPLD----------- 211
Query: 174 NRASYAFLREALRSSVGS--PLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDL---- 227
FL + L S L LCCR L E + + + + +L+ L ++ +++
Sbjct: 212 -----KFLSDLLTKVEQSHGALHLCCRKLHIEKMAVDSLLRILKTLRLDFIQELEVFYWC 266
Query: 228 -RFNNLGLRGLSVIIPHVARFQHLASLRLHYVHGDS----RQPSVDGEDNFRYFLAQMGR 282
F L LS I + R +L SL+L Y R+PS YF +Q+
Sbjct: 267 RDFLVLAEPNLSAI--QLGRIFNLRSLKLFYYKWAFSSWVRRPS-------SYFFSQLTM 317
Query: 283 FTCLRELSMGSSLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLD 342
LR+L + S L G+L +LS L PL SLE+ C LL D+ +L+RS H LKKLD
Sbjct: 318 LGHLRKLHLSHSYLVGKLHYILSCLWVPLHSLEICNCKLLDTDITYLSRSHHTTCLKKLD 377
Query: 343 LSGNDLSGSQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYG 402
LS NDLS P LL+A + TL HL+L C L D L A LP L +C+ L L L
Sbjct: 378 LSVNDLSYMIPGPLGTLLRAVSGTLQHLDLKHCWLKDAHLSALLPALCRCSHLSSLSLSD 437
Query: 403 NPLSMAGLKELLRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEA 462
NP+S A L LL ++ EL+ V++P PVDC L + +NE+K +++A
Sbjct: 438 NPISSACLLSLLEHTMGLMELKQVLYPIPVDCCIYL------HGVCRGPVNEDKLCQLQA 491
Query: 463 ELHQLLLASGRAHVLWT 479
E+ + L A +A + W+
Sbjct: 492 EIQKQLQAMQQADMQWS 508
>gi|148356236 PRAME family member 15 [Homo sapiens]
Length = 478
Score = 171 bits (432), Expect = 2e-42
Identities = 142/474 (29%), Positives = 227/474 (47%), Gaps = 57/474 (12%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L+ R +L+ Q A L LP ELFP LF AF ++ L+ +V WPF L +
Sbjct: 11 LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRP 70
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ P E+ QAV+ GL A L +P R+ L+VLD+ +
Sbjct: 71 LIK------------MPCLEAFQAVLDGLDALLTQG-----VRP--RRWKLQVLDLQDVC 111
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCIAQQ-------QGGAAEPGPAPIPVEVRVDLRVNRA 176
++ +W + A+A C Q G P+ V V + L+ NR
Sbjct: 112 EN-------FWMVW--SEAMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLK-NRT 161
Query: 177 -----SYAFLREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNN 231
+Y L R + L LCC+ L+ +P RN ++L++++ C++ V++
Sbjct: 162 LDEYLTYLLLWVKQRKDL---LHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW 218
Query: 232 LGLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSM 291
+ L L+ P++ ++L L L ++ ++ F Q + CL++L M
Sbjct: 219 V-LPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYM 277
Query: 292 GS-SLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSG 350
S S L G LDQLLS L++ L+ L + C LL DL+ L++ P + LK LDLSG L+
Sbjct: 278 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 337
Query: 351 SQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGL 410
L P Q LL+ AATL +L+L +C + D+Q+ A LP L++C L GNP+ MA L
Sbjct: 338 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATL 397
Query: 411 KELLRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAEL 464
+ LL ++ L ++P P + Y + ++ +FA++ AEL
Sbjct: 398 ENLLSHTIILKNLCVELYPAPRESYGA-----------DGTLCWSRFAQIRAEL 440
>gi|61102721 PRAME family member 9 [Homo sapiens]
Length = 478
Score = 171 bits (432), Expect = 2e-42
Identities = 142/474 (29%), Positives = 227/474 (47%), Gaps = 57/474 (12%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L+ R +L+ Q A L LP ELFP LF AF ++ L+ +V WPF L +
Sbjct: 11 LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRP 70
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ P E+ QAV+ GL A L +P R+ L+VLD+ +
Sbjct: 71 LIK------------MPCLEAFQAVLDGLDALLTQG-----VRP--RRWKLQVLDLQDVC 111
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCIAQQ-------QGGAAEPGPAPIPVEVRVDLRVNRA 176
++ +W + A+A C Q G P+ V V + L+ NR
Sbjct: 112 EN-------FWMVW--SEAMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLK-NRT 161
Query: 177 -----SYAFLREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNN 231
+Y L R + L LCC+ L+ +P RN ++L++++ C++ V++
Sbjct: 162 LDEYLTYLLLWVKQRKDL---LHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW 218
Query: 232 LGLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSM 291
+ L L+ P++ ++L L L ++ ++ F Q + CL++L M
Sbjct: 219 V-LPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYM 277
Query: 292 GS-SLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSG 350
S S L G LDQLLS L++ L+ L + C LL DL+ L++ P + LK LDLSG L+
Sbjct: 278 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 337
Query: 351 SQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGL 410
L P Q LL+ AATL +L+L +C + D+Q+ A LP L++C L GNP+ MA L
Sbjct: 338 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATL 397
Query: 411 KELLRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAEL 464
+ LL ++ L ++P P + Y + ++ +FA++ AEL
Sbjct: 398 ENLLSHTIILKNLCVELYPAPRESYGA-----------DGTLCWSRFAQIRAEL 440
>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
Length = 513
Score = 169 bits (428), Expect = 5e-42
Identities = 140/470 (29%), Positives = 224/470 (47%), Gaps = 49/470 (10%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L R +L+ Q A L LP ELFP LF AF ++ L+ +V WPF L +
Sbjct: 46 LLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRP 105
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ P E+ QAV+ GL A L +P R+ L+VLD+ +
Sbjct: 106 LIK------------MPCLEAFQAVLDGLDALLTQG-----VRP--RRWKLQVLDLQDVC 146
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPI-----PVEVRVDLRV-NRAS 177
++ +W + A+A C + P P+ V V+L + NR
Sbjct: 147 EN-------FWMVW--SEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 197
Query: 178 YAFLREALR--SSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGLR 235
+L L L LCC+ L+ +P RN ++L++++ C++ V++ + L
Sbjct: 198 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWI-LP 256
Query: 236 GLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMGS-S 294
L+ P++ ++L L L ++ ++ F Q + CL++L M S S
Sbjct: 257 ILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVS 316
Query: 295 LLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQLA 354
L G LDQLLS L++ L+ L + C LL DL+ L++ P + LK LDLSG L+ L
Sbjct: 317 FLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLV 376
Query: 355 PFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKELL 414
P Q LL+ AATL +L+L +C + D+Q+ A LP L++C L GNP+ MA L+ LL
Sbjct: 377 PLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLL 436
Query: 415 RDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAEL 464
++ L ++P P + Y + ++ +FA++ AEL
Sbjct: 437 SHTIILKNLCLELYPAPQESYGA-----------DGTLCWSRFAQIRAEL 475
>gi|239746677 PREDICTED: preferentially expressed antigen in
melanoma-like [Homo sapiens]
Length = 520
Score = 169 bits (427), Expect = 7e-42
Identities = 156/497 (31%), Positives = 221/497 (44%), Gaps = 77/497 (15%)
Query: 3 TLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQ 62
+L+ L+ +L + + L L LFP L AF L+ LV WPF L
Sbjct: 69 SLLELAAHSLLSNEASVPLVLEQLTVNLFPPLLTAAFAKGHRKALKALVQAWPFRFLHLG 128
Query: 63 QLLQECAHCSRALLQERPSTESMQAVILGLTA-RLHTSEPGASTQPLCRKHALRVLDMTG 121
L+ + P+ +S+QAV+ GL A H + P RK LR+LD T
Sbjct: 129 SLIVQW-----------PNQDSLQAVVDGLEAFSAHRACP--------RKSELRMLDFT- 168
Query: 122 LLDD--------GVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRV 173
LD G + W +A A T A A P P
Sbjct: 169 -LDSEQVFYCGKGASEALTKFPFWLPSAVKAETPQA-----TARPKPLD----------- 211
Query: 174 NRASYAFLREALRSSVGS--PLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDL---- 227
FL + L S L LCCR L E + + + + +L+ L ++ +++
Sbjct: 212 -----KFLSDLLTKVEQSHGALHLCCRKLHIEKMAVDSLLRILKTLRLDFIQELEVFYWC 266
Query: 228 -RFNNLGLRGLSVIIPHVARFQHLASLRLHYVHGDS----RQPSVDGEDNFRYFLAQMGR 282
F L LS I + R +L S +L Y R+PS YF +Q+
Sbjct: 267 RDFLVLAEPNLSAI--QLGRIFNLRSFKLFYYKWAFSSWVRRPS-------SYFFSQLTM 317
Query: 283 FTCLRELSMGSSLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLD 342
LR+L + S L G+L +LS L PL SLE+ C LL D+ +L+RS H LKKLD
Sbjct: 318 LGHLRKLHLSHSYLVGKLHYILSCLWVPLHSLEICNCKLLDTDITYLSRSHHTTCLKKLD 377
Query: 343 LSGNDLSGSQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYG 402
LS NDLS P LL+A + TL HL+L C L D L A LP L +C+ L L L
Sbjct: 378 LSVNDLSYMIPGPLGTLLRAVSGTLQHLDLKHCWLKDAHLSALLPALCRCSHLSSLSLSD 437
Query: 403 NPLSMAGLKELLRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEA 462
NP+S A L LL ++ EL+ V++P PVDC L + +NE+K +++A
Sbjct: 438 NPISSACLLSLLEHTMGLMELKQVLYPIPVDCCIYL------HGVCRGPVNEDKLCQLQA 491
Query: 463 ELHQLLLASGRAHVLWT 479
E+ + L A +A + W+
Sbjct: 492 EIQKQLQAMQQADMQWS 508
>gi|153792112 PRAME family member 20 [Homo sapiens]
Length = 475
Score = 166 bits (419), Expect = 6e-41
Identities = 141/474 (29%), Positives = 224/474 (47%), Gaps = 58/474 (12%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L+ R +L+ + A L LP ELFP LF AF + L+ +V WPF L
Sbjct: 9 LLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWPFLRLPLGS 68
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ RP E+ QAV+ GL A L + + R+ L+VLD+ +
Sbjct: 69 LMK------------RPCPETFQAVLDGLDALL-------THRVRLRRWKLQVLDLQDVS 109
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPI-----PVEVRVDLRVNRASY 178
++ +W + A+AR C+ P P+ V +DL + +
Sbjct: 110 EN-------FWMVW--SEAMARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTL 160
Query: 179 ------AFLREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNL 232
FL R + + LCC+ L+ + N +L+ ++ C++ V++ N
Sbjct: 161 DEYFTCLFLWVKQREGL---VHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCN-W 216
Query: 233 GLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNF-RYFLAQMGRFTCLRELSM 291
L L+ P++ + ++L L L + DSR S + + F F Q + CL++L M
Sbjct: 217 TLPVLAEFTPYLGQMRNLRKLVLSDI--DSRYISPEQKKEFVTQFTTQFLKLRCLQKLYM 274
Query: 292 GS-SLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSG 350
S S L G LDQ+LS L++ L L + C LL DL+ L++ P LK LDLSG L+
Sbjct: 275 NSVSFLEGHLDQMLSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLAN 334
Query: 351 SQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGL 410
L P Q LL+ AATL +L+L +C + D+Q+ A LP L++C L GNP+S A L
Sbjct: 335 FSLVPLQVLLEKVAATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATL 394
Query: 411 KELLRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAEL 464
+ LL ++ L ++P P + Y+ + + +FA++ AEL
Sbjct: 395 ENLLCHTIRLNNLCLELYPAPRESYD-----------VRGIVCRSRFAQLGAEL 437
>gi|153945800 PRAME family member 21 [Homo sapiens]
Length = 475
Score = 166 bits (419), Expect = 6e-41
Identities = 141/474 (29%), Positives = 224/474 (47%), Gaps = 58/474 (12%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L+ R +L+ + A L LP ELFP LF AF + L+ +V WPF L
Sbjct: 9 LLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWPFLRLPLGS 68
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ RP E+ QAV+ GL A L + + R+ L+VLD+ +
Sbjct: 69 LMK------------RPCPETFQAVLDGLDALL-------THRVRLRRWKLQVLDLQDVS 109
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPI-----PVEVRVDLRVNRASY 178
++ +W + A+AR C+ P P+ V +DL + +
Sbjct: 110 EN-------FWMVW--SEAMARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTL 160
Query: 179 ------AFLREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNL 232
FL R + + LCC+ L+ + N +L+ ++ C++ V++ N
Sbjct: 161 DEYFTCLFLWVKQREGL---VHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCN-W 216
Query: 233 GLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNF-RYFLAQMGRFTCLRELSM 291
L L+ P++ + ++L L L + DSR S + + F F Q + CL++L M
Sbjct: 217 TLPVLAEFTPYLGQMRNLRKLVLSDI--DSRYISPEQKKEFVTQFTTQFLKLRCLQKLYM 274
Query: 292 GS-SLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSG 350
S S L G LDQ+LS L++ L L + C LL DL+ L++ P LK LDLSG L+
Sbjct: 275 NSVSFLEGHLDQMLSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLAN 334
Query: 351 SQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGL 410
L P Q LL+ AATL +L+L +C + D+Q+ A LP L++C L GNP+S A L
Sbjct: 335 FSLVPLQVLLEKVAATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATL 394
Query: 411 KELLRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAEL 464
+ LL ++ L ++P P + Y+ + + +FA++ AEL
Sbjct: 395 ENLLCHTIRLNNLCLELYPAPRESYD-----------VRGIVCRSRFAQLGAEL 437
>gi|59676593 PRAME family member 7 [Homo sapiens]
Length = 474
Score = 164 bits (416), Expect = 1e-40
Identities = 125/434 (28%), Positives = 215/434 (49%), Gaps = 24/434 (5%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L+ +++L+ Q A + LPRELFP LF AF ++ L+ +V WPF L
Sbjct: 9 LLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWPFTRLPLGS 68
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ P ES+++V+ G+ L T E +P R+ L+VLD+ +
Sbjct: 69 LMKS------------PHLESLKSVLEGVDVLL-TQE----VRP--RQSKLQVLDLRNVD 109
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVNRASYAFLRE 183
++ + G + + A+++ A G P + +++ + R L E
Sbjct: 110 ENFCDIFSGATASFP--EALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLE 167
Query: 184 ALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGLRGLSVIIPH 243
+ G L +CC++L+ +P+ + + +L +++ C++ V++ L L P+
Sbjct: 168 WGKQRKGL-LHVCCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCP-WELSTLVKFAPY 225
Query: 244 VARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMGS-SLLSGRLDQ 302
+ + ++L L L + + P + F +Q + + LSM S S L G LDQ
Sbjct: 226 LGQMRNLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQ 285
Query: 303 LLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQLAPFQGLLQA 362
LL LQ+ LE + + C L DL+ L+ P LK+LDL G L+ P GLL+
Sbjct: 286 LLRCLQASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQ 345
Query: 363 SAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKELLRDSVAQAE 422
ATL L+L +C + D+QL A LP+L++C+ L GN +SMA L+ LLR +V ++
Sbjct: 346 VVATLQTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSK 405
Query: 423 LRTVVHPFPVDCYE 436
L ++P P++ Y+
Sbjct: 406 LSLELYPAPLESYD 419
>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
[Homo sapiens]
Length = 474
Score = 164 bits (416), Expect = 1e-40
Identities = 125/434 (28%), Positives = 215/434 (49%), Gaps = 24/434 (5%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L+ +++L+ Q A + LPRELFP LF AF ++ L+ +V WPF L
Sbjct: 9 LLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWPFTRLPLGS 68
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ P ES+++V+ G+ L T E +P R+ L+VLD+ +
Sbjct: 69 LMKS------------PHLESLKSVLEGVDVLL-TQE----VRP--RQSKLQVLDLRNVD 109
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVNRASYAFLRE 183
++ + G + + A+++ A G P + +++ + R L E
Sbjct: 110 ENFCDIFSGATASFP--EALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLE 167
Query: 184 ALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGLRGLSVIIPH 243
+ G L +CC++L+ +P+ + + +L +++ C++ V++ L L P+
Sbjct: 168 WGKQRKGL-LHVCCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCP-WELSTLVKFAPY 225
Query: 244 VARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMGS-SLLSGRLDQ 302
+ + ++L L L + + P + F +Q + + LSM S S L G LDQ
Sbjct: 226 LGQMRNLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQ 285
Query: 303 LLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQLAPFQGLLQA 362
LL LQ+ LE + + C L DL+ L+ P LK+LDL G L+ P GLL+
Sbjct: 286 LLRCLQASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQ 345
Query: 363 SAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKELLRDSVAQAE 422
ATL L+L +C + D+QL A LP+L++C+ L GN +SMA L+ LLR +V ++
Sbjct: 346 VVATLQTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSK 405
Query: 423 LRTVVHPFPVDCYE 436
L ++P P++ Y+
Sbjct: 406 LSLELYPAPLESYD 419
>gi|59676587 PRAME family member 8 [Homo sapiens]
Length = 474
Score = 164 bits (415), Expect = 2e-40
Identities = 125/434 (28%), Positives = 215/434 (49%), Gaps = 24/434 (5%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L+ +++L+ Q A + LPRELFP LF AF ++ L+ +V WPF L
Sbjct: 9 LLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWPFTRLPLGS 68
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ P ES+++V+ G+ L T E +P R+ L+VLD+ +
Sbjct: 69 LMKS------------PHLESLKSVLEGVDVLL-TQE----VRP--RQSKLQVLDLRNVD 109
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVNRASYAFLRE 183
++ + G + + A+++ A G P + +++ + R L E
Sbjct: 110 ENFCDIFSGATASFP--EALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLE 167
Query: 184 ALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGLRGLSVIIPH 243
+ G L +CC++L+ +P+ + + +L +++ C++ V++ L L P+
Sbjct: 168 WGKQRKGL-LHVCCQELQVFGMPIHSIIEVLNMVELDCIQEVEVCCP-WELSTLVKFAPY 225
Query: 244 VARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMGS-SLLSGRLDQ 302
+ + ++L L L + + P + F +Q + + LSM S S L G LDQ
Sbjct: 226 LGQMRNLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQ 285
Query: 303 LLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQLAPFQGLLQA 362
LL LQ+ LE + + C L DL+ L+ P LK+LDL G L+ P GLL+
Sbjct: 286 LLRCLQASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQ 345
Query: 363 SAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKELLRDSVAQAE 422
ATL L+L +C + D+QL A LP+L++C+ L GN +SMA L+ LLR +V ++
Sbjct: 346 VVATLQTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSK 405
Query: 423 LRTVVHPFPVDCYE 436
L ++P P++ Y+
Sbjct: 406 LSLELYPAPLESYD 419
>gi|124249372 PRAME family member 12 [Homo sapiens]
Length = 483
Score = 159 bits (401), Expect = 7e-39
Identities = 130/445 (29%), Positives = 214/445 (48%), Gaps = 46/445 (10%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L+ + +L+ + A L LPRELFP LF AF + L +V WPF L
Sbjct: 9 LLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWPFTCLPLGS 68
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ C + E +AV+ GL A L +P R+ L+VLD+ +
Sbjct: 69 LMKSC------------NLEIFRAVLEGLDALL-----AQKVRP--RRWKLQVLDLRNV- 108
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCIAQQQ--GGAAEPGPAPIPVEVRVDLRVNRASYAFL 181
D +W +A++ +++++ G PG P+ V +DL L
Sbjct: 109 ------DENFWGIWSGASALSPEALSKRRTAGNCPRPGGQQ-PLMVILDLCFKNG---ML 158
Query: 182 REALRSSVG------SPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGLR 235
E L + L +CC++L+ + + + +L ++ C++ V++
Sbjct: 159 DECLTHFLEWGKQRKGLLHVCCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCP----W 214
Query: 236 GLSVII---PHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMG 292
LS++I P++ + ++L L L +H + P E F +Q + ++L M
Sbjct: 215 ELSILIRFAPYLGQMRNLRKLVLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMH 274
Query: 293 S-SLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGS 351
S S L G LDQLL LQ+PLE++ + C L DL+ L+ P LK+LDL G L+
Sbjct: 275 SVSFLEGHLDQLLRCLQAPLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHF 334
Query: 352 QLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLK 411
P LL+ + ATL L+L +C + D+QL A LP L++C+ L GN +SMA L+
Sbjct: 335 SPEPLSVLLEQAEATLQTLDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALE 394
Query: 412 ELLRDSVAQAELRTVVHPFPVDCYE 436
LLR +V ++L ++P P++ Y+
Sbjct: 395 NLLRHTVGLSKLSLELYPAPLESYD 419
>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
Length = 474
Score = 152 bits (383), Expect = 9e-37
Identities = 123/433 (28%), Positives = 208/433 (48%), Gaps = 24/433 (5%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L+ + +L Q A L LPRELFP LF AF ++ VL+ +V WPFP L
Sbjct: 9 LLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWPFPCLPLGS 68
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ P E + V+ G+ L +P R+ L+VL++ +
Sbjct: 69 LMKT------------PDLEILHYVVDGIDCLL-----AQKVRP--RRRKLQVLELRDVD 109
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVNRASYAFLRE 183
++ G + A+++ + E P + ++V + + +F
Sbjct: 110 ENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSG 169
Query: 184 ALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGLRGLSVIIPH 243
++ GS + LCC + + + N +L+ + ++ +++ +N + P+
Sbjct: 170 WVQHRRGS-VHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEI-WNMCWPCMIVEFSPY 227
Query: 244 VARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMGS-SLLSGRLDQ 302
+++ ++L L + G S D ++ F Q + CL++L M S S L G LDQ
Sbjct: 228 LSQMRNLRKLFIS--DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQ 285
Query: 303 LLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQLAPFQGLLQA 362
LLS L++ L+ L + C LL DL+ L++ P + LK LDLSG L+ L P Q LL+
Sbjct: 286 LLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEK 345
Query: 363 SAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKELLRDSVAQAE 422
AATL +L+L +C + D+Q+ A LP L++C L GNP+SMA L+ LL ++
Sbjct: 346 VAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKN 405
Query: 423 LRTVVHPFPVDCY 435
L ++P P + Y
Sbjct: 406 LCLELYPAPRESY 418
>gi|226437621 PRAME family member 11 [Homo sapiens]
Length = 436
Score = 149 bits (375), Expect = 7e-36
Identities = 125/436 (28%), Positives = 206/436 (47%), Gaps = 49/436 (11%)
Query: 38 AFMDKKTVVLRELVHTWPFPLLSFQQLLQECAHCSRALLQERPSTESMQAVILGLTARLH 97
AF ++ L+ +V WPF L + L++ P E+ QAV+ GL A L
Sbjct: 3 AFSRRRCEALKLMVQAWPFRRLPLRPLIK------------MPCLEAFQAVLDGLDALLT 50
Query: 98 TSEPGASTQPLCRKHALRVLDMTGLLDDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAE 157
+P R+ L+VLD+ + ++ +W + A+A C +
Sbjct: 51 QG-----VRP--RRWKLQVLDLQDVCEN-------FWMVW--SEAMAHGCFLNAKRNKTP 94
Query: 158 PGPAPI-----PVEVRVDLRV-NRASYAFLREALR--SSVGSPLRLCCRDLRAEDLPMRN 209
P P+ V V+L + NR +L L L LCC+ L+ +P RN
Sbjct: 95 VQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRN 154
Query: 210 TVALLQLLDAGCLRRVDLRFNNLGLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDG 269
++L++++ C++ V++ + L L+ P++ ++L L L ++
Sbjct: 155 IRSILKMVNLDCIQEVEVNCKWI-LPILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQK 213
Query: 270 EDNFRYFLAQMGRFTCLRELSMGS-SLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRF 328
++ F Q + CL++L M S S L G LDQLLS L++ L+ L + C LL DL+
Sbjct: 214 KEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKH 273
Query: 329 LARSPHAAHLKKLDLSGNDLSGSQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPI 388
L++ P + LK LDLSG L+ L P Q LL+ AATL +L+L +C + D+Q+ A LP
Sbjct: 274 LSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPA 333
Query: 389 LTQCASLRYLGLYGNPLSMAGLKELLRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLL 448
L++C L GNP+ MA L+ LL ++ L ++P P + Y
Sbjct: 334 LSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQESYGA----------- 382
Query: 449 EASINEEKFARVEAEL 464
+ ++ +FA++ AEL
Sbjct: 383 DGTLCWSRFAQIRAEL 398
>gi|88942379 PREDICTED: PRAME family member [Homo sapiens]
Length = 395
Score = 139 bits (349), Expect = 8e-33
Identities = 84/244 (34%), Positives = 135/244 (55%), Gaps = 2/244 (0%)
Query: 193 LRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGLRGLSVIIPHVARFQHLAS 252
L LCC+ L+ +P RN ++L++++ C++ V++ + L L+ P++ ++L
Sbjct: 97 LHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWV-LPILTQFTPYLGHMRNLQK 155
Query: 253 LRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMGS-SLLSGRLDQLLSTLQSPL 311
L L ++ ++ F Q + CL++L M S S L G LDQLLS L++ L
Sbjct: 156 LVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSL 215
Query: 312 ESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQLAPFQGLLQASAATLLHLE 371
+ L + C LL DL+ L++ P + LK LDLSG L+ L P Q LL+ AATL +L+
Sbjct: 216 KVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLD 275
Query: 372 LTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKELLRDSVAQAELRTVVHPFP 431
L +C + D+Q+ A LP L++C L GNP+SMA L+ LL ++ L ++P P
Sbjct: 276 LDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAP 335
Query: 432 VDCY 435
+ Y
Sbjct: 336 RESY 339
>gi|153791443 PRAME family member 18 [Homo sapiens]
Length = 479
Score = 123 bits (308), Expect = 4e-28
Identities = 119/441 (26%), Positives = 204/441 (46%), Gaps = 47/441 (10%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L+ + +L+ Q A L LPRELFP LF AF ++ VL+ +V WPFP L
Sbjct: 9 LLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWPFPCLPLGS 68
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ P E + V+ G+ L +P R+ L+VL+M +
Sbjct: 69 LMKT------------PDLEILHYVVDGIDCLL-----AQKVRP--RRWKLQVLEMRDV- 108
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAP---IPVEVRVDLRVNRASY-- 178
D ++W ++ + A + E P P++V +D+ + S
Sbjct: 109 ------DENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDE 162
Query: 179 ------AFLREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNL 232
+++ RS + LCC + + + N +L+ + ++ +++ +N
Sbjct: 163 DLSFFSGWVQHRRRS-----VHLCCTKVVNYSMNILNFRNILETVYPDSIQVLEI-WNMC 216
Query: 233 GLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNF-RYFLAQMGRFTCLRELSM 291
++ + ++++ ++L L + G PS + + F + R L+ L M
Sbjct: 217 WPCMVAEVSRYLSQMKNLRKLFIS--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYM 274
Query: 292 GS-SLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSG 350
G LDQL+ L+SPLE+L L + +L EDL+ L P + LK+L+LS L
Sbjct: 275 RRIRFFEGYLDQLIRCLKSPLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRF 334
Query: 351 SQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGL 410
+L P + LL+ AATL L L +C + D++L LP L++C++L +GN SM GL
Sbjct: 335 IRLEPLRALLEKVAATLQTLFLVDCGIGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGL 394
Query: 411 KELLRDSVAQAELRTVVHPFP 431
K+LLR + + L +P P
Sbjct: 395 KDLLRHTGRLSNLSLETYPAP 415
>gi|194306638 PRAME family member 3 [Homo sapiens]
Length = 481
Score = 122 bits (306), Expect = 7e-28
Identities = 114/431 (26%), Positives = 195/431 (45%), Gaps = 27/431 (6%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L+ + +L Q A L LPRELFP LF AF ++ VL+ +V WPFP L
Sbjct: 11 LLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWPFPCLPLGS 70
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ P E + V+ G+ L +P R+ L+VL++ +
Sbjct: 71 LMKT------------PDLEILHYVVDGIDCLL-----AQKVRP--RRRKLQVLELRDVD 111
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVNRASYAFLRE 183
++ G + A+++ + E P + ++V + + +F
Sbjct: 112 ENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSG 171
Query: 184 ALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGLRGLSVIIPH 243
++ GS + LCC + + + N +L+ + ++ +++ + +I+
Sbjct: 172 WVQHRRGS-VHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEI----WNMCWPCMIVEF 226
Query: 244 VARFQHLASLRLHYVHGDSRQ--PSVDGEDNFRYFLAQMGRFTCLRELSMGS-SLLSGRL 300
+ + +LR ++ R S E F + + R L+ L + G L
Sbjct: 227 IRYLSQMRNLRKLFISDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHL 286
Query: 301 DQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQLAPFQGLL 360
DQL+ L+SPLE+L L + L DL+ L R P + LK+L+LS L +L P + LL
Sbjct: 287 DQLIRCLRSPLETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALL 346
Query: 361 QASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKELLRDSVAQ 420
+ AATL L L +C + D++L LP L+ C++L +GN SM GLK+LLR +
Sbjct: 347 EKVAATLQTLFLVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRL 406
Query: 421 AELRTVVHPFP 431
+ L +P P
Sbjct: 407 SNLSLETYPAP 417
>gi|154800493 PRAME family member 22 [Homo sapiens]
Length = 481
Score = 119 bits (299), Expect = 5e-27
Identities = 114/431 (26%), Positives = 194/431 (45%), Gaps = 27/431 (6%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L+ + +L Q A L LPRELFP LF AF ++ VL+ +V WPFP L
Sbjct: 11 LLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWPFPCLPLGS 70
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ P E + V+ G+ L +P R+ L+VL++ +
Sbjct: 71 LMKT------------PDLEILHYVVDGIDCLL-----AQKVRP--RRWKLQVLELRDVD 111
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVNRASYAFLRE 183
++ G + A+++ + E P + ++V + + +F
Sbjct: 112 ENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSG 171
Query: 184 ALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGLRGLSVIIPH 243
++ GS + LCC + + + N +L+ + ++ +++ + +I+
Sbjct: 172 WVQHRRGS-VHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEI----WNMCWPCMIVEF 226
Query: 244 VARFQHLASLRLHYVHGDSRQ--PSVDGEDNFRYFLAQMGRFTCLRELSMGS-SLLSGRL 300
+ +LR ++ R S E F + + R L+ L + G L
Sbjct: 227 SRYLSQMRNLRKLFISDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHL 286
Query: 301 DQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQLAPFQGLL 360
DQL+ L+SPLE+L L + L DL+ L R P + LK+L+LS L +L P + LL
Sbjct: 287 DQLIRCLRSPLETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALL 346
Query: 361 QASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKELLRDSVAQ 420
+ AATL L L +C + D++L LP L+ C++L +GN SM GLK+LLR +
Sbjct: 347 EKVAATLQTLFLVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRL 406
Query: 421 AELRTVVHPFP 431
+ L +P P
Sbjct: 407 SNLSLETYPAP 417
>gi|194306635 PRAME family member 19 [Homo sapiens]
Length = 479
Score = 119 bits (299), Expect = 5e-27
Identities = 118/441 (26%), Positives = 203/441 (46%), Gaps = 47/441 (10%)
Query: 4 LVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQ 63
L+ L+ + +L+ Q A L LPRELFP LF AF ++ VL+ +V WPFP L
Sbjct: 9 LLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWPFPCLPLGS 68
Query: 64 LLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLL 123
L++ P E + V+ G+ L +P R+ L+VL+M +
Sbjct: 69 LMKT------------PDLEILHYVVDGIDCLL-----AQKVRP--RRWKLQVLEMRDV- 108
Query: 124 DDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAP---IPVEVRVDLRVNRASY-- 178
D ++W ++ + A + E P P++V +D+ + S
Sbjct: 109 ------DENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDE 162
Query: 179 ------AFLREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNL 232
+++ RS + LCC + + + N +L+ + ++ +++ +N
Sbjct: 163 DLSFFSGWVQHRRRS-----VHLCCTKVVNYSMNILNFRNILETVYPDSIQVLEI-WNMC 216
Query: 233 GLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNF-RYFLAQMGRFTCLRELSM 291
++ + ++++ ++L L + G PS + + F + R L+ L M
Sbjct: 217 WPCMVAEVSRYLSQMKNLRKLFIS--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYM 274
Query: 292 GS-SLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSG 350
G LDQL+ L+SPLE+L L + +L EDL+ L P + LK+L+LS L
Sbjct: 275 RRIRFFEGYLDQLIRCLKSPLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRF 334
Query: 351 SQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGL 410
+L P + LL+ AATL L L +C + ++L LP L++C++L +GN SM GL
Sbjct: 335 IRLEPLRALLEKVAATLQTLFLVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGL 394
Query: 411 KELLRDSVAQAELRTVVHPFP 431
K+LLR + + L +P P
Sbjct: 395 KDLLRHTGRLSNLSLETYPAP 415
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,892,386
Number of Sequences: 37866
Number of extensions: 860431
Number of successful extensions: 3225
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 3039
Number of HSP's gapped (non-prelim): 170
length of query: 493
length of database: 18,247,518
effective HSP length: 106
effective length of query: 387
effective length of database: 14,233,722
effective search space: 5508450414
effective search space used: 5508450414
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.