Guide to the Human Genome
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Search of human proteins with 7661858

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7661858 Rho GTPase activating protein 11A isoform 1 [Homo
sapiens]
         (1023 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7661858 Rho GTPase activating protein 11A isoform 1 [Homo sap...  2032   0.0  
gi|40788018 Rho GTPase activating protein 11A isoform 2 [Homo sa...   986   0.0  
gi|89886350 Rho GTPase activating protein 11B [Homo sapiens]          438   e-122
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]             85   3e-16
gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a...    85   3e-16
gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b...    85   3e-16
gi|91208437 GEM interacting protein [Homo sapiens]                     82   2e-15
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]            82   3e-15
gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]              81   4e-15
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]    81   4e-15
gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi...    81   4e-15
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi...    81   4e-15
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]        79   2e-14
gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Hom...    79   3e-14
gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Hom...    79   3e-14
gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [H...    79   3e-14
gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]            78   5e-14
gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]         77   6e-14
gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]         77   6e-14
gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]                75   4e-13
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi...    75   4e-13
gi|54860105 nadrin isoform 2 [Homo sapiens]                            75   4e-13
gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapi...    75   4e-13
gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi...    75   4e-13
gi|54860079 nadrin isoform 1 [Homo sapiens]                            74   7e-13
gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a ...    74   9e-13
gi|56119110 family with sequence similarity 13, member A1 isofor...    71   5e-12
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa...    71   6e-12
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa...    71   6e-12
gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b ...    71   6e-12

>gi|7661858 Rho GTPase activating protein 11A isoform 1 [Homo sapiens]
          Length = 1023

 Score = 2032 bits (5265), Expect = 0.0
 Identities = 1023/1023 (100%), Positives = 1023/1023 (100%)

Query: 1    MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 60
            MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
Sbjct: 1    MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 60

Query: 61   EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 120
            EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
Sbjct: 61   EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 120

Query: 121  LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 180
            LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN
Sbjct: 121  LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 180

Query: 181  VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 240
            VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR
Sbjct: 181  VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 240

Query: 241  VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN 300
            VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN
Sbjct: 241  VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN 300

Query: 301  RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF 360
            RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF
Sbjct: 301  RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF 360

Query: 361  NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC 420
            NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC
Sbjct: 361  NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC 420

Query: 421  FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG 480
            FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG
Sbjct: 421  FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG 480

Query: 481  LLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRMSWTGPNNSSFQEVDANEASSM 540
            LLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRMSWTGPNNSSFQEVDANEASSM
Sbjct: 481  LLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRMSWTGPNNSSFQEVDANEASSM 540

Query: 541  VENLEVENSLEPDIMVEKSPATSCELTPSNLNNKHNSNITSSPLSGDENNMTKETLVKVQ 600
            VENLEVENSLEPDIMVEKSPATSCELTPSNLNNKHNSNITSSPLSGDENNMTKETLVKVQ
Sbjct: 541  VENLEVENSLEPDIMVEKSPATSCELTPSNLNNKHNSNITSSPLSGDENNMTKETLVKVQ 600

Query: 601  KAFSESGSNLHALMNQRQSSVTNVGKVKLTEPSYLEDSPEENLFETNDLTIVESKEKYEH 660
            KAFSESGSNLHALMNQRQSSVTNVGKVKLTEPSYLEDSPEENLFETNDLTIVESKEKYEH
Sbjct: 601  KAFSESGSNLHALMNQRQSSVTNVGKVKLTEPSYLEDSPEENLFETNDLTIVESKEKYEH 660

Query: 661  HTGKGEKCFSERDFSPLQTQTFNRETTIKCYSTQMKMEHEKDIHSNMPKDYLSKQEFSSD 720
            HTGKGEKCFSERDFSPLQTQTFNRETTIKCYSTQMKMEHEKDIHSNMPKDYLSKQEFSSD
Sbjct: 661  HTGKGEKCFSERDFSPLQTQTFNRETTIKCYSTQMKMEHEKDIHSNMPKDYLSKQEFSSD 720

Query: 721  EEIKKQQSPKDKLNNKLKENENMMEGNLPKCAAHSKDEARSSFSQQSTCVVTNLSKPRPM 780
            EEIKKQQSPKDKLNNKLKENENMMEGNLPKCAAHSKDEARSSFSQQSTCVVTNLSKPRPM
Sbjct: 721  EEIKKQQSPKDKLNNKLKENENMMEGNLPKCAAHSKDEARSSFSQQSTCVVTNLSKPRPM 780

Query: 781  RIAKQQSLETCEKTVSESSQMTEHRKVSDHIQWFNKLSLNEPNRIKVKSPLKFQRTPVRQ 840
            RIAKQQSLETCEKTVSESSQMTEHRKVSDHIQWFNKLSLNEPNRIKVKSPLKFQRTPVRQ
Sbjct: 781  RIAKQQSLETCEKTVSESSQMTEHRKVSDHIQWFNKLSLNEPNRIKVKSPLKFQRTPVRQ 840

Query: 841  SVRRINSLLEYSRQPTGHKLASLGDTASPLVKSVSCDGALSSCIESASKDSSVSCIKSGP 900
            SVRRINSLLEYSRQPTGHKLASLGDTASPLVKSVSCDGALSSCIESASKDSSVSCIKSGP
Sbjct: 841  SVRRINSLLEYSRQPTGHKLASLGDTASPLVKSVSCDGALSSCIESASKDSSVSCIKSGP 900

Query: 901  KEQKSMSCEESNIGAISKSSMELPSKSFLKMRKHPDSVNASLRSTTVYKQKILSDGQVKV 960
            KEQKSMSCEESNIGAISKSSMELPSKSFLKMRKHPDSVNASLRSTTVYKQKILSDGQVKV
Sbjct: 901  KEQKSMSCEESNIGAISKSSMELPSKSFLKMRKHPDSVNASLRSTTVYKQKILSDGQVKV 960

Query: 961  PLDDLTNHDIVKPVVNNNMGISSGINNRVLRRPSERGRAWYKGSPKHPIGKTQLLPTSKP 1020
            PLDDLTNHDIVKPVVNNNMGISSGINNRVLRRPSERGRAWYKGSPKHPIGKTQLLPTSKP
Sbjct: 961  PLDDLTNHDIVKPVVNNNMGISSGINNRVLRRPSERGRAWYKGSPKHPIGKTQLLPTSKP 1020

Query: 1021 VDL 1023
            VDL
Sbjct: 1021 VDL 1023


>gi|40788018 Rho GTPase activating protein 11A isoform 2 [Homo
           sapiens]
          Length = 501

 Score =  986 bits (2550), Expect = 0.0
 Identities = 495/496 (99%), Positives = 496/496 (100%)

Query: 1   MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 60
           MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
Sbjct: 1   MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 60

Query: 61  EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 120
           EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
Sbjct: 61  EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 120

Query: 121 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 180
           LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN
Sbjct: 121 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 180

Query: 181 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 240
           VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR
Sbjct: 181 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 240

Query: 241 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN 300
           VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN
Sbjct: 241 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN 300

Query: 301 RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF 360
           RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF
Sbjct: 301 RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF 360

Query: 361 NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC 420
           NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC
Sbjct: 361 NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC 420

Query: 421 FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG 480
           FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG
Sbjct: 421 FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG 480

Query: 481 LLFSPDVDEKLPKKGS 496
           LLFSPDVDEKLPKKG+
Sbjct: 481 LLFSPDVDEKLPKKGT 496


>gi|89886350 Rho GTPase activating protein 11B [Homo sapiens]
          Length = 267

 Score =  438 bits (1126), Expect = e-122
 Identities = 220/231 (95%), Positives = 222/231 (96%), Gaps = 5/231 (2%)

Query: 1   MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 60
           MWDQRLV+LALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
Sbjct: 1   MWDQRLVKLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 60

Query: 61  EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 120
           EYGHIPSFLVDACTSLE+HIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
Sbjct: 61  EYGHIPSFLVDACTSLEEHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 120

Query: 121 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 180
           LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKA LLLSCLLADHTVHVLRYFFNFLRN
Sbjct: 121 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAILLLSCLLADHTVHVLRYFFNFLRN 180

Query: 181 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTL 231
           VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSN EKK      V QTL
Sbjct: 181 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNAEKK-----GVYQTL 226


>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
          Length = 698

 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 59/171 (34%), Positives = 84/171 (49%), Gaps = 7/171 (4%)

Query: 42  IGGKIFGVPFNALPHSAVPEYGHIPSFLVDACTSL--EDHIHTEGLFRKSGSVIRLKALK 99
           +GG IFG       H        +   LV+ C     E  +  EGLFR  G    ++ L+
Sbjct: 148 LGGGIFGQRLEETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQ 207

Query: 100 NKVDHGEGCL--SSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATL 157
           +  D GE  L  S+     +A LLK + RELPEP++P   +E  L   QL T+++ + TL
Sbjct: 208 DSFDCGEKPLFDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTL 267

Query: 158 LLS---CLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQ 205
            L+     L     ++LRY   FL  V   S+ NKM   NLA +F PN+L+
Sbjct: 268 ELAKQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILR 318


>gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a
           [Homo sapiens]
          Length = 1071

 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 49/152 (32%), Positives = 80/152 (52%), Gaps = 5/152 (3%)

Query: 83  EGLFRKSGSVIRLKALKNKVDHGE----GCLSSAPPCDIAGLLKQFFRELPEPILPADL- 137
           EG+FR SGS + +  +KN  + GE    G  +      IAG+LK +FR L  P+ P D+ 
Sbjct: 523 EGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIF 582

Query: 138 HEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAV 197
           H+ +        +E+      +  +L   T+ ++RY F FL ++S  S EN MD  NLA+
Sbjct: 583 HDLMACVTMDNLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAI 642

Query: 198 IFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQ 229
            F P+L+   EGH+++S        ++  ++Q
Sbjct: 643 CFGPSLMSVPEGHDQVSCQAHVNELIKTIIIQ 674


>gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b
           [Homo sapiens]
          Length = 836

 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 49/152 (32%), Positives = 80/152 (52%), Gaps = 5/152 (3%)

Query: 83  EGLFRKSGSVIRLKALKNKVDHGE----GCLSSAPPCDIAGLLKQFFRELPEPILPADL- 137
           EG+FR SGS + +  +KN  + GE    G  +      IAG+LK +FR L  P+ P D+ 
Sbjct: 523 EGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIF 582

Query: 138 HEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAV 197
           H+ +        +E+      +  +L   T+ ++RY F FL ++S  S EN MD  NLA+
Sbjct: 583 HDLMACVTMDNLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAI 642

Query: 198 IFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQ 229
            F P+L+   EGH+++S        ++  ++Q
Sbjct: 643 CFGPSLMSVPEGHDQVSCQAHVNELIKTIIIQ 674


>gi|91208437 GEM interacting protein [Homo sapiens]
          Length = 970

 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 25/189 (13%)

Query: 46  IFGVPFNALPHSAVPEYGHIPSFLVDACTSLEDH--IHTEGLFRKSGSVIRLKALKNKVD 103
           +FGV F  LP     E   +P F+V  CT+  +H  +  +G++R SGS +R++ L    +
Sbjct: 548 LFGVDFLQLPRDFPEE---VP-FVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFE 603

Query: 104 HGEGC--LSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQL---------GTEE- 151
           +G     LS   P D++ +LK+F +EL EP++P  L++A +   +          GT   
Sbjct: 604 NGRALVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSP 663

Query: 152 -----KNKATLLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQT 206
                ++  TLL+   L D   + LR+    L  V+ R  ENKM ++NL ++F P LL+ 
Sbjct: 664 SPEVIRSLKTLLVQ--LPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRP 721

Query: 207 SEGHEKMSS 215
            +G    S+
Sbjct: 722 PDGPRAASA 730


>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
          Length = 946

 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 55/154 (35%), Positives = 81/154 (52%), Gaps = 9/154 (5%)

Query: 83  EGLFRKSGSVIRLKALKNKVDHGE-----GCLSSAPPCD-IAGLLKQFFRELPEPILPAD 136
           EG+FR SG+ +R+  +++  + GE     GC  +A   D +AG+LK +FR L  P+ P D
Sbjct: 539 EGIFRVSGAQLRVSEIRDAFERGEDPLVEGC--TAHDLDSVAGVLKLYFRSLEPPLFPPD 596

Query: 137 LHEALLKAQQL-GTEEKNKATLLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNL 195
           L   LL + +L  T E+ +    L   L    + VLRY F FL +++  S EN MD  NL
Sbjct: 597 LFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFLNHLAQYSDENMMDPYNL 656

Query: 196 AVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQ 229
           AV F P LL    G + ++        +Q  +VQ
Sbjct: 657 AVCFGPTLLPVPAGQDPVALQGRVNQLVQTLIVQ 690


>gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]
          Length = 439

 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 64/207 (30%), Positives = 99/207 (47%), Gaps = 23/207 (11%)

Query: 47  FGVPFNALPHSAVPEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKNKVDHG 105
           FGV    L     PE   IP  L +    L+ H + TEG+FR+S +   ++ ++ K + G
Sbjct: 242 FGVSLQHLQEKN-PEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMG 300

Query: 106 EGCLSSAPPCDI---------AGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAT 156
                   P D          A +LK F RELPEP+L  DL+  ++    +   ++  AT
Sbjct: 301 L-------PVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPAT 353

Query: 157 LLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSN 216
           L +   L +    VLR+   FL  +S  S +NKM ++NLAV+F PNLL       K ++ 
Sbjct: 354 LQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWA-----KDAAI 408

Query: 217 TEKKLRLQAAVVQTLIDYASDIGRVPD 243
           T K +       + L+D+  ++   PD
Sbjct: 409 TLKAINPINTFTKFLLDHQGELFPSPD 435


>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
          Length = 771

 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 66/216 (30%), Positives = 100/216 (46%), Gaps = 19/216 (8%)

Query: 60  PEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPC--D 116
           P Y  +P  +   C  LE H + T G+FR   S  R++ L+ + D G            D
Sbjct: 202 PIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHD 261

Query: 117 IAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLAD---HTVHVLRY 173
           +A LLK+F R++P+P+L  +L+ A +    L  EE+     LL  LL      T+H L  
Sbjct: 262 VAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQ 321

Query: 174 FFNFLR-----NVSLRSSE---NKMDSSNLAVIFAPNLLQTSEGHEK-----MSSNTEKK 220
           F + +      N+S    E   NKM S NLA IF PNLL   +  +K      S+  E+ 
Sbjct: 322 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 381

Query: 221 LRLQAAVVQTLIDYASDIGRVPDFILEKIPAMLGID 256
             + A V + + +Y +     PD   E + ++L  D
Sbjct: 382 TAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETD 417


>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
           sapiens]
          Length = 765

 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 66/216 (30%), Positives = 100/216 (46%), Gaps = 19/216 (8%)

Query: 60  PEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPC--D 116
           P Y  +P  +   C  LE H + T G+FR   S  R++ L+ + D G            D
Sbjct: 405 PIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHD 464

Query: 117 IAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLAD---HTVHVLRY 173
           +A LLK+F R++P+P+L  +L+ A +    L  EE+     LL  LL      T+H L  
Sbjct: 465 VAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQ 524

Query: 174 FFNFLR-----NVSLRSSE---NKMDSSNLAVIFAPNLLQTSEGHEK-----MSSNTEKK 220
           F + +      N+S    E   NKM S NLA IF PNLL   +  +K      S+  E+ 
Sbjct: 525 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 584

Query: 221 LRLQAAVVQTLIDYASDIGRVPDFILEKIPAMLGID 256
             + A V + + +Y +     PD   E + ++L  D
Sbjct: 585 TAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETD 620


>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
           sapiens]
          Length = 974

 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 66/216 (30%), Positives = 100/216 (46%), Gaps = 19/216 (8%)

Query: 60  PEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPC--D 116
           P Y  +P  +   C  LE H + T G+FR   S  R++ L+ + D G            D
Sbjct: 405 PIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHD 464

Query: 117 IAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLAD---HTVHVLRY 173
           +A LLK+F R++P+P+L  +L+ A +    L  EE+     LL  LL      T+H L  
Sbjct: 465 VAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQ 524

Query: 174 FFNFLR-----NVSLRSSE---NKMDSSNLAVIFAPNLLQTSEGHEK-----MSSNTEKK 220
           F + +      N+S    E   NKM S NLA IF PNLL   +  +K      S+  E+ 
Sbjct: 525 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 584

Query: 221 LRLQAAVVQTLIDYASDIGRVPDFILEKIPAMLGID 256
             + A V + + +Y +     PD   E + ++L  D
Sbjct: 585 TAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETD 620


>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
          Length = 818

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 56/177 (31%), Positives = 89/177 (50%), Gaps = 12/177 (6%)

Query: 67  SFLVDACTS--LEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLS-----SAPPCDIAG 119
           +F ++AC +  LE  +  EGLFR + S  +LK LK  +D    C+      SA P  IAG
Sbjct: 269 AFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDC---CVVDVQEYSADPHAIAG 325

Query: 120 LLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVH-VLRYFFNFL 178
            LK + RELPEP++  +L++  ++A  +  ++K    L  +C       H  +RY   FL
Sbjct: 326 ALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFL 385

Query: 179 RNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYA 235
             +S     NKM  SN+A++  PNLL            T   L++   +++ +I +A
Sbjct: 386 SKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQI-VGIIEPIIQHA 441


>gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Homo
           sapiens]
          Length = 622

 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 63/215 (29%), Positives = 100/215 (46%), Gaps = 11/215 (5%)

Query: 45  KIFGVPFNAL---PHSAVPEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKN 100
           ++FGVP ++L    H  +P    +P  L    + LE   +  EG+ R  GS  R+K L+ 
Sbjct: 266 RLFGVPLDSLLEADHKVLPST-QVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQ 324

Query: 101 KVDH----GEGCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAT 156
           K++     G          D + LLK+F R+LP P+L A+   A      +   ++    
Sbjct: 325 KLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQV 384

Query: 157 L-LLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSS 215
           L LL  +L +   + L+    FLR V  R   NKM   N++ + APNL        K+  
Sbjct: 385 LHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPK 444

Query: 216 NTEKKLRLQAA-VVQTLIDYASDIGRVPDFILEKI 249
             EK+L   AA VVQ ++ Y   +  V  F++ ++
Sbjct: 445 GKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQV 479


>gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo
           sapiens]
          Length = 622

 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 63/215 (29%), Positives = 100/215 (46%), Gaps = 11/215 (5%)

Query: 45  KIFGVPFNAL---PHSAVPEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKN 100
           ++FGVP ++L    H  +P    +P  L    + LE   +  EG+ R  GS  R+K L+ 
Sbjct: 266 RLFGVPLDSLLEADHKVLPST-QVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQ 324

Query: 101 KVDH----GEGCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAT 156
           K++     G          D + LLK+F R+LP P+L A+   A      +   ++    
Sbjct: 325 KLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQV 384

Query: 157 L-LLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSS 215
           L LL  +L +   + L+    FLR V  R   NKM   N++ + APNL        K+  
Sbjct: 385 LHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPK 444

Query: 216 NTEKKLRLQAA-VVQTLIDYASDIGRVPDFILEKI 249
             EK+L   AA VVQ ++ Y   +  V  F++ ++
Sbjct: 445 GKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQV 479


>gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [Homo
           sapiens]
          Length = 622

 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 63/215 (29%), Positives = 100/215 (46%), Gaps = 11/215 (5%)

Query: 45  KIFGVPFNAL---PHSAVPEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKN 100
           ++FGVP ++L    H  +P    +P  L    + LE   +  EG+ R  GS  R+K L+ 
Sbjct: 266 RLFGVPLDSLLEADHKVLPST-QVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQ 324

Query: 101 KVDH----GEGCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAT 156
           K++     G          D + LLK+F R+LP P+L A+   A      +   ++    
Sbjct: 325 KLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQV 384

Query: 157 L-LLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSS 215
           L LL  +L +   + L+    FLR V  R   NKM   N++ + APNL        K+  
Sbjct: 385 LHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPK 444

Query: 216 NTEKKLRLQAA-VVQTLIDYASDIGRVPDFILEKI 249
             EK+L   AA VVQ ++ Y   +  V  F++ ++
Sbjct: 445 GKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQV 479


>gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]
          Length = 663

 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 67/214 (31%), Positives = 98/214 (45%), Gaps = 11/214 (5%)

Query: 46  IFGVPFNAL---PHSAVPEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKNK 101
           +F VP  AL       VP    IP       + +E+  + TEGL R  G+ IR+K L  +
Sbjct: 321 LFCVPLTALLEQDQRKVPGM-RIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQE 379

Query: 102 VD----HGEGCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKN-KAT 156
           ++     G     S    D A LLK F RELP+P+L  +  +A    Q L T+++  +A 
Sbjct: 380 LEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQAL 439

Query: 157 LLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSN 216
            LL  LL D     L+    FL+ V     +NKM   N+A++ APNL        K S  
Sbjct: 440 NLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQ 499

Query: 217 TEKKLRLQAA-VVQTLIDYASDIGRVPDFILEKI 249
            E  +    A  +  LI Y   +  +P FI+ ++
Sbjct: 500 REFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQV 533


>gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]
          Length = 1528

 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 56/175 (32%), Positives = 89/175 (50%), Gaps = 9/175 (5%)

Query: 46   IFGVPFNA-LPHSAVPEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKNKVD 103
            +FGVP    +  +  P    +P  +  A   L +H +   GLFRKSG   R++AL+   +
Sbjct: 1075 VFGVPLTVNVQRTGQP----LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNE 1130

Query: 104  HGEGCLS--SAPPCDIAGLLKQFFRELPEPILPADLHEALLKA-QQLGTEEKNKATLLLS 160
                C++       D+A +LKQ+FR+LPEP++   L E  L+  Q +  +++ +A     
Sbjct: 1131 GAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAI 1190

Query: 161  CLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSS 215
             LL D    VL+    FL +V+    EN+M  +NLAV  AP+L   +    + SS
Sbjct: 1191 MLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSS 1245


>gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]
          Length = 1091

 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 56/175 (32%), Positives = 89/175 (50%), Gaps = 9/175 (5%)

Query: 46  IFGVPFNA-LPHSAVPEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKNKVD 103
           +FGVP    +  +  P    +P  +  A   L +H +   GLFRKSG   R++AL+   +
Sbjct: 638 VFGVPLTVNVQRTGQP----LPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNE 693

Query: 104 HGEGCLS--SAPPCDIAGLLKQFFRELPEPILPADLHEALLKA-QQLGTEEKNKATLLLS 160
               C++       D+A +LKQ+FR+LPEP++   L E  L+  Q +  +++ +A     
Sbjct: 694 GAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAI 753

Query: 161 CLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSS 215
            LL D    VL+    FL +V+    EN+M  +NLAV  AP+L   +    + SS
Sbjct: 754 MLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSS 808


>gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]
          Length = 555

 Score = 74.7 bits (182), Expect = 4e-13
 Identities = 60/183 (32%), Positives = 90/183 (49%), Gaps = 10/183 (5%)

Query: 65  IPSFLVDACTSL-EDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDI---AGL 120
           IP  L    T L E  + TEGLFR+S SV  ++ ++   + G+  ++     DI   A +
Sbjct: 331 IPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKP-VNFDDYGDIHIPAVI 389

Query: 121 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 180
           LK F RELP+P+L    +E +L    + +  +      +   L +H   VLRY   FL  
Sbjct: 390 LKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHA 449

Query: 181 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 240
           VS  S  NKM+SSNLA +F  NL+  S+G   +S+     +       + LI+Y   I  
Sbjct: 450 VSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNM-----FTELLIEYYEKIFS 504

Query: 241 VPD 243
            P+
Sbjct: 505 TPE 507


>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo
           sapiens]
          Length = 1085

 Score = 74.7 bits (182), Expect = 4e-13
 Identities = 51/171 (29%), Positives = 84/171 (49%), Gaps = 7/171 (4%)

Query: 51  FNALPHSAVPEYGHIPSFLVDACTSLED--HIHTEGLFRKSGSVIRLKALKNKVDHGEGC 108
           FN    + V + G +   +V++C    +   +  +G+FR SGS + +  +KN  + GE  
Sbjct: 504 FNGDLETFVKDSGQVIPLIVESCIRFINLYGLQHQGIFRVSGSQVEVNDIKNSFERGENP 563

Query: 109 L----SSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGT-EEKNKATLLLSCLL 163
           L    S+     +AG+LK +FR L  P+ P +    L+   ++    E+      L   L
Sbjct: 564 LADDQSNHDINSVAGVLKLYFRGLENPLFPKERFNDLISCIRIDNLYERALHIRKLLLTL 623

Query: 164 ADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMS 214
               + V+RY F FL ++S  S EN MD  NLA+ F P L+   E  +++S
Sbjct: 624 PRSVLIVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMPVPEIQDQVS 674


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 74.7 bits (182), Expect = 4e-13
 Identities = 68/239 (28%), Positives = 105/239 (43%), Gaps = 18/239 (7%)

Query: 70  VDACTSL--EDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSS--APPCDIAGLLKQFF 125
           ++AC  L  E  +  EGLFR      +LK LK  +D     L    + P  +AG LK + 
Sbjct: 269 IEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYL 328

Query: 126 RELPEPILPADLHEALLKAQQLGTEEKNKATLLLSC-LLADHTVHVLRYFFNFLRNVSLR 184
           RELPEP++  +L+E   +   +  ++K    L  +C  L        RY   FL  ++  
Sbjct: 329 RELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQT 388

Query: 185 SSENKMDSSNLAVIFAPNLL-QTSEGH-EKMSSNTEKKLRLQAAVVQTLIDYASDIGRVP 242
           S  NKM  SN+A++  PNLL   +EG   +M++ T   +    AV++ +I +A       
Sbjct: 389 SDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATSVHV---VAVIEPIIQHAD------ 439

Query: 243 DFILEKIPAML--GIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKP 299
            F  E++   +      L    S   F  G     G  +RKR  S+       + K  P
Sbjct: 440 WFFPEEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSGTLERKRPASMAVMEGDLVKKESP 498


>gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo
           sapiens]
          Length = 433

 Score = 74.7 bits (182), Expect = 4e-13
 Identities = 60/183 (32%), Positives = 90/183 (49%), Gaps = 10/183 (5%)

Query: 65  IPSFLVDACTSL-EDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDI---AGL 120
           IP  L    T L E  + TEGLFR+S SV  ++ ++   + G+  ++     DI   A +
Sbjct: 209 IPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKP-VNFDDYGDIHIPAVI 267

Query: 121 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 180
           LK F RELP+P+L    +E +L    + +  +      +   L +H   VLRY   FL  
Sbjct: 268 LKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHA 327

Query: 181 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 240
           VS  S  NKM+SSNLA +F  NL+  S+G   +S+     +       + LI+Y   I  
Sbjct: 328 VSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNM-----FTELLIEYYEKIFS 382

Query: 241 VPD 243
            P+
Sbjct: 383 TPE 385


>gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo
           sapiens]
          Length = 464

 Score = 74.7 bits (182), Expect = 4e-13
 Identities = 60/183 (32%), Positives = 90/183 (49%), Gaps = 10/183 (5%)

Query: 65  IPSFLVDACTSL-EDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDI---AGL 120
           IP  L    T L E  + TEGLFR+S SV  ++ ++   + G+  ++     DI   A +
Sbjct: 240 IPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKP-VNFDDYGDIHIPAVI 298

Query: 121 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 180
           LK F RELP+P+L    +E +L    + +  +      +   L +H   VLRY   FL  
Sbjct: 299 LKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHA 358

Query: 181 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 240
           VS  S  NKM+SSNLA +F  NL+  S+G   +S+     +       + LI+Y   I  
Sbjct: 359 VSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNM-----FTELLIEYYEKIFS 413

Query: 241 VPD 243
            P+
Sbjct: 414 TPE 416


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 73.9 bits (180), Expect = 7e-13
 Identities = 55/173 (31%), Positives = 86/173 (49%), Gaps = 10/173 (5%)

Query: 70  VDACTSL--EDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSS--APPCDIAGLLKQFF 125
           ++AC  L  E  +  EGLFR      +LK LK  +D     L    + P  +AG LK + 
Sbjct: 269 IEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYL 328

Query: 126 RELPEPILPADLHEALLKAQQLGTEEKNKATLLLSC-LLADHTVHVLRYFFNFLRNVSLR 184
           RELPEP++  +L+E   +   +  ++K    L  +C  L        RY   FL  ++  
Sbjct: 329 RELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQT 388

Query: 185 SSENKMDSSNLAVIFAPNLL-QTSEGH-EKMSSNTEKKLRLQAAVVQTLIDYA 235
           S  NKM  SN+A++  PNLL   +EG   +M++ T   +    AV++ +I +A
Sbjct: 389 SDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATSVHV---VAVIEPIIQHA 438


>gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a
           [Homo sapiens]
          Length = 1099

 Score = 73.6 bits (179), Expect = 9e-13
 Identities = 48/171 (28%), Positives = 82/171 (47%), Gaps = 7/171 (4%)

Query: 51  FNALPHSAVPEYGHIPSFLVDACTSLED--HIHTEGLFRKSGSVIRLKALKNKVDHGEGC 108
           FN    + + + G     +V++C    +   +  +G+FR  GS + +  +KN  + GE  
Sbjct: 504 FNGSMEAFIKDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDP 563

Query: 109 L----SSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQL-GTEEKNKATLLLSCLL 163
           L    +      +AG+LK +FR L  P+ P +  + L+   +L    E+      +   L
Sbjct: 564 LVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTL 623

Query: 164 ADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMS 214
               + V+RY F FL ++S  S EN MD  NLA+ F P L+   +G + +S
Sbjct: 624 PRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVS 674


>gi|56119110 family with sequence similarity 13, member A1 isoform a
           [Homo sapiens]
          Length = 1023

 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 54/173 (31%), Positives = 83/173 (47%), Gaps = 5/173 (2%)

Query: 45  KIFGVPFNALPHSAVPEYGHIPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALKNKVD 103
           K+FGV    L    + E G IP+ + +    L  H +  EGLFR +G+V  ++ L+ K +
Sbjct: 39  KLFGVSLQELERQGLTENG-IPAVVWNIVEYLTQHGLTQEGLFRVNGNVKVVEQLRLKFE 97

Query: 104 HGEGCL--SSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLL-LS 160
            G           C  A LLK F RELP+ ++ + L    ++  Q G  +  +++L  L 
Sbjct: 98  SGVPVELGKDGDVCSAASLLKLFLRELPDSLITSALQPRFIQLFQDGRNDVQESSLRDLI 157

Query: 161 CLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKM 213
             L D    +L+Y   FL  V+    +N+M+  NLA +F PN      G E M
Sbjct: 158 KELPDTHYCLLKYLCQFLTKVAKHHVQNRMNVHNLATVFGPNCFHVPPGLEGM 210


>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
           sapiens]
          Length = 653

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 53/170 (31%), Positives = 78/170 (45%), Gaps = 7/170 (4%)

Query: 43  GGKIFGVPFNALPHSAVPEYGHIPSFLVDACTSL--EDHIHTEGLFRKSGSVIRLKALKN 100
           GG IFG                +   LV+ C     +  +  EGLFR  G    +K L++
Sbjct: 34  GGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQD 93

Query: 101 KVDHGE--GCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLL 158
             D GE     S+     +A LLK + RELPEP++P   +E  L   +L ++E+      
Sbjct: 94  AFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKE 153

Query: 159 LSCLLADHTV---HVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQ 205
           L+  +    V   ++L+Y   FL  V   S  NKM   NLA +F PN+L+
Sbjct: 154 LAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILR 203


>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
           sapiens]
          Length = 748

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 53/170 (31%), Positives = 78/170 (45%), Gaps = 7/170 (4%)

Query: 43  GGKIFGVPFNALPHSAVPEYGHIPSFLVDACTSL--EDHIHTEGLFRKSGSVIRLKALKN 100
           GG IFG                +   LV+ C     +  +  EGLFR  G    +K L++
Sbjct: 129 GGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQD 188

Query: 101 KVDHGE--GCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLL 158
             D GE     S+     +A LLK + RELPEP++P   +E  L   +L ++E+      
Sbjct: 189 AFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKE 248

Query: 159 LSCLLADHTV---HVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQ 205
           L+  +    V   ++L+Y   FL  V   S  NKM   NLA +F PN+L+
Sbjct: 249 LAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILR 298


>gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b
           [Homo sapiens]
          Length = 1075

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 43/140 (30%), Positives = 70/140 (50%), Gaps = 5/140 (3%)

Query: 80  IHTEGLFRKSGSVIRLKALKNKVDHGEGCL----SSAPPCDIAGLLKQFFRELPEPILPA 135
           +  +G+FR  GS + +  +KN  + GE  L    +      +AG+LK +FR L  P+ P 
Sbjct: 511 LQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPK 570

Query: 136 DLHEALLKAQQL-GTEEKNKATLLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSN 194
           +  + L+   +L    E+      +   L    + V+RY F FL ++S  S EN MD  N
Sbjct: 571 ERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYN 630

Query: 195 LAVIFAPNLLQTSEGHEKMS 214
           LA+ F P L+   +G + +S
Sbjct: 631 LAICFGPTLMHIPDGQDPVS 650


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,710,348
Number of Sequences: 37866
Number of extensions: 1783101
Number of successful extensions: 6622
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 106
Number of HSP's successfully gapped in prelim test: 177
Number of HSP's that attempted gapping in prelim test: 6097
Number of HSP's gapped (non-prelim): 597
length of query: 1023
length of database: 18,247,518
effective HSP length: 112
effective length of query: 911
effective length of database: 14,006,526
effective search space: 12759945186
effective search space used: 12759945186
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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