BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7661690 coiled-coil domain containing 9 [Homo sapiens] (531 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7661690 coiled-coil domain containing 9 [Homo sapiens] 1105 0.0 gi|155029552 hypothetical protein LOC388115 [Homo sapiens] 74 3e-13 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 72 1e-12 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 67 3e-11 gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 67 3e-11 gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 67 3e-11 gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 66 7e-11 gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 65 2e-10 gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 65 2e-10 gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 64 4e-10 gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 62 1e-09 gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 59 8e-09 gi|50962882 G patch domain containing 8 [Homo sapiens] 59 8e-09 gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 58 2e-08 gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 57 5e-08 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 55 1e-07 gi|17975763 myelin transcription factor 1 [Homo sapiens] 55 1e-07 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 55 2e-07 gi|55956788 nucleolin [Homo sapiens] 55 2e-07 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 54 3e-07 gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 54 4e-07 gi|30795231 brain abundant, membrane attached signal protein 1 [... 54 5e-07 gi|221316599 chromogranin B precursor [Homo sapiens] 54 5e-07 gi|60498973 myelin transcription factor 1-like [Homo sapiens] 54 5e-07 gi|78042577 MAP7 domain containing 1 [Homo sapiens] 54 5e-07 gi|33286446 opioid growth factor receptor [Homo sapiens] 53 6e-07 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 53 8e-07 gi|148746195 trichohyalin [Homo sapiens] 53 8e-07 gi|62244004 modulator of estrogen induced transcription isoform ... 53 8e-07 gi|63176611 modulator of estrogen induced transcription isoform ... 53 8e-07 >gi|7661690 coiled-coil domain containing 9 [Homo sapiens] Length = 531 Score = 1105 bits (2857), Expect = 0.0 Identities = 531/531 (100%), Positives = 531/531 (100%) Query: 1 MAATLDLKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRS 60 MAATLDLKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRS Sbjct: 1 MAATLDLKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRS 60 Query: 61 VEKENVAVESEKNLGPSRRSPGTPRPPGASKGGRTPPQQGGRAGMGRASRSWEGSPGEQP 120 VEKENVAVESEKNLGPSRRSPGTPRPPGASKGGRTPPQQGGRAGMGRASRSWEGSPGEQP Sbjct: 61 VEKENVAVESEKNLGPSRRSPGTPRPPGASKGGRTPPQQGGRAGMGRASRSWEGSPGEQP 120 Query: 121 RGGGAGGRGRRGRGRGSPHLSGAGDTSISDRKSKEWEERRRQNIEKMNEEMEKIAEYERN 180 RGGGAGGRGRRGRGRGSPHLSGAGDTSISDRKSKEWEERRRQNIEKMNEEMEKIAEYERN Sbjct: 121 RGGGAGGRGRRGRGRGSPHLSGAGDTSISDRKSKEWEERRRQNIEKMNEEMEKIAEYERN 180 Query: 181 QREGVLEPNPVRNFLDDPRRRSGPLEESERDRREESRRHGRNWGGPDFERVRCGLEHERQ 240 QREGVLEPNPVRNFLDDPRRRSGPLEESERDRREESRRHGRNWGGPDFERVRCGLEHERQ Sbjct: 181 QREGVLEPNPVRNFLDDPRRRSGPLEESERDRREESRRHGRNWGGPDFERVRCGLEHERQ 240 Query: 241 GRRAGLGSAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDG 300 GRRAGLGSAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDG Sbjct: 241 GRRAGLGSAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDG 300 Query: 301 MFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRA 360 MFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRA Sbjct: 301 MFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRA 360 Query: 361 YSDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEE 420 YSDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEE Sbjct: 361 YSDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEE 420 Query: 421 DEEWEDISEDEEEEEIEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEP 480 DEEWEDISEDEEEEEIEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEP Sbjct: 421 DEEWEDISEDEEEEEIEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEP 480 Query: 481 QAPGTPSSPFSPPSGHQPVSDWGEEVELNSPRTTHLAGALSPGEAWPFESV 531 QAPGTPSSPFSPPSGHQPVSDWGEEVELNSPRTTHLAGALSPGEAWPFESV Sbjct: 481 QAPGTPSSPFSPPSGHQPVSDWGEEVELNSPRTTHLAGALSPGEAWPFESV 531 >gi|155029552 hypothetical protein LOC388115 [Homo sapiens] Length = 534 Score = 74.3 bits (181), Expect = 3e-13 Identities = 81/279 (29%), Positives = 107/279 (38%), Gaps = 40/279 (14%) Query: 263 EYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKD-----GPVPAHEPSHR-- 315 +Y +WKQERE+ID RL RHR G WRR WD +K +D G PA S R Sbjct: 234 DYAQWKQEREQIDLARLARHRDAQGDWRRPWDLDKAKSTLQDCSQLRGEGPARAGSRRGP 293 Query: 316 YDDQAWARPPKPP----TFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETK 371 Q PP P G+ A A+ + R R +A + + E + Sbjct: 294 RSHQKLQPPPLLPDGKGRGGQASRPSVAPATGSKARGKERLTGRARRWDMKEDKEELEGQ 353 Query: 372 EGAASPAPETPQPTSPETSPKETPMQPPEI-PAPAHRPPEDEGEENEGEEDEEWEDISED 430 EG+ S ET P+ E + K++ M+ + APA P E +GE Sbjct: 354 EGSQS-TRET--PSEEEQAQKQSGMEQGRLGSAPAASPALASPEGPKGE----------- 399 Query: 431 EEEEEIEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEPQAPGTPSSPF 490 V P Q P+ AP + S G+P E + PG SP Sbjct: 400 ------SVASTASSVPCSP-QEPDLAP--LDLSLGGAGIPGPRESGCVLGLRPGAQESPV 450 Query: 491 SPPSG--HQPVSDWGEEVEL---NSPRTTHLAGALSPGE 524 S P G QP+ + EL P AG PGE Sbjct: 451 SWPEGSKQQPLGWSNHQAELEVQTCPEPQRGAGLPEPGE 489 Score = 71.6 bits (174), Expect = 2e-12 Identities = 33/47 (70%), Positives = 43/47 (91%) Query: 9 SKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAP 55 S++EKDAELD+RI ALR+KN+AL+RRYQEI+EDR++AE G+AVT P Sbjct: 58 SRQEKDAELDRRIVALRKKNQALLRRYQEIQEDRRQAEQGGMAVTTP 104 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 72.4 bits (176), Expect = 1e-12 Identities = 100/452 (22%), Positives = 164/452 (36%), Gaps = 35/452 (7%) Query: 14 DAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRSVEKENVAVESEKN 73 +A D+ +E K A + IEE +A E V V RK E + S+ Sbjct: 577 EAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRK------EKTEILSDDL 630 Query: 74 LGPSRRSPGTPRPPGASKGGRTPPQQGGRAGMGRASRSWEGSPGEQPRGGGAGGRGRRGR 133 + S G + G ++ G G + W+ E+ +G GRG R Sbjct: 631 TDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDE--EREKGEKDKGRGEMER 688 Query: 134 -GRGSPHLSGAGDTSISDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVR 192 G G L+ + D + +E +ER + + ++ N+EME+ E E + E Sbjct: 689 PGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEE 748 Query: 193 NFLDDPRRRSGPLEESERDR------REESRRHGRNWGGPDFERVRCGLEHERQGR---- 242 + + G EE E +R R++ R G+ G + G E E +GR Sbjct: 749 EEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEK 808 Query: 243 -RAGLGSAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGM 301 G G++ RE E +E E +E + G+ + E + E+ +G Sbjct: 809 EEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGE 868 Query: 302 FK----DGPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAA 357 + +G E +++ + GE + + E + + Sbjct: 869 EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEG 928 Query: 358 PRAYSDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENE 417 + + E ++G E + E E E EGEE E Sbjct: 929 EGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE----------EGEGEGEEEGEGEGEEGE 978 Query: 418 GE-EDEEWEDISEDEEEEEIEVEEGDEEEPAQ 448 GE E+EE E E+EE EE EEG+ EE + Sbjct: 979 GEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGE 1010 Score = 48.9 bits (115), Expect = 1e-05 Identities = 98/445 (22%), Positives = 146/445 (32%), Gaps = 62/445 (13%) Query: 6 DLKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRSVEKEN 65 +L KEE + E R+ R QE+EE ++ EG R+ EKE Sbjct: 695 ELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEE-EKEG 753 Query: 66 VAVES---EKNLGPSRRSPGTPRPPGASKGGRTPPQQGGRAGMGRASRSWEGSPGEQPRG 122 E E+ G + G R G ++ G G G + EG E+ G Sbjct: 754 EGKEEGEGEEVEGEREKEEGE-RKKEERAGKEEKGEEEGDQGEGEEEET-EGRGEEKEEG 811 Query: 123 GGA-GGRGRRGRG-RGSPHLSGAGDTSISDRKSKEWEERRRQNIEKMNEEMEKIAEYERN 180 G GG G+G R G G+ + + +E E + K EE E+ E E Sbjct: 812 GEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEE-GEGEEE 870 Query: 181 QREGVLEPNPVRNFLDDPRRRSGPLEESERDRREESRRHGRNWGGPDFERVRCGLEHERQ 240 EG E G EE E + EE G G E + Sbjct: 871 GEEGEGE---------------GEEEEGEGEGEEEGEGEGEEEEG------------EGE 903 Query: 241 GRRAGLGSAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDG 300 G G G + G E E + E E+ + E G+ E + + +G Sbjct: 904 GEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEG------EDGEGEGEEEEGEWEG 957 Query: 301 MFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRA 360 ++G E ++ + GE + E + + Sbjct: 958 EEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017 Query: 361 YSDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEEN--EG 418 + + E +EG E + E R E EGEEN Sbjct: 1018 EGEVEGEVEGEEGEGEGEEEEGEEEGEE------------------REKEGEGEENRRNR 1059 Query: 419 EEDEEWEDISEDEEEEEIEVEEGDE 443 EE+EE E ++ EEE E ++G+E Sbjct: 1060 EEEEEEEGKYQETGEEENERQDGEE 1084 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 67.4 bits (163), Expect = 3e-11 Identities = 93/406 (22%), Positives = 150/406 (36%), Gaps = 21/406 (5%) Query: 137 SPHLSGAGDTSISDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLD 196 S +S DT + K +E+ RQ IEK E E+ E ER +RE E R Sbjct: 278 SREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREK 337 Query: 197 DPRRRSGPLEESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSM 256 + R + +RDR +E R D +R R + + R+ S Sbjct: 338 EKERERERERDRDRDRTKERDRDRDRERDRDRDRERSS-DRNKDRSRSREKSRDRERERE 396 Query: 257 TGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFK---DGPVPAHEPS 313 RER ++ERE+ + +R R+ +R+ + ++ D + + + E + Sbjct: 397 REREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAA 456 Query: 314 HRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEG 373 ++ + W + T E+ + + E RR + K Y D D + G Sbjct: 457 YQERLKNWEIRERKKT-REYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRG 515 Query: 374 AASPAPETPQPTSPETSPKETPMQPPEIP-------APAHRPPEDEGEENEGEEDE---- 422 +A + E ++ + E+ A H P+ E + E E + Sbjct: 516 SALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQP 575 Query: 423 --EWEDISEDEEEEEIEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVP-FSPEEPLLE 479 + E SE+EEEE+ E EE EEP ++ + PE P P P S Sbjct: 576 QIKQEPESEEEEEEKQEKEE-KREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNAT 634 Query: 480 PQAPGTPS-SPFSPPSGHQPVSDWGEEVELNSPRTTHLAGALSPGE 524 P PG S P + P EE + L + SPG+ Sbjct: 635 PNTPGDESPCGIIIPHENSPDQQQPEEHRPKIGLSLKLGASNSPGQ 680 >gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] Length = 770 Score = 67.4 bits (163), Expect = 3e-11 Identities = 102/406 (25%), Positives = 153/406 (37%), Gaps = 76/406 (18%) Query: 157 EERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPL--EESERDRRE 214 E++RR+ E+ E +R+ + LE +R+ + R+ P E+S DR E Sbjct: 19 EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGE 78 Query: 215 ESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRWKQEREKI 274 E P + R H R+ + R E +WK R K Sbjct: 79 EDDSLAIK---PPQQMSRKEKVHHRKDEK-----------------RKE--KWKHARVKE 116 Query: 275 -DQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEF 333 + ER +RHR+ + RREW+ +K M A E S R D+ K + Sbjct: 117 REHERRKRHREEQDKARREWERQKRREM-------AREHSRRERDRLEQLERKRERERKM 169 Query: 334 LSQHKA--EASSRRRRKSSRPQAKAAPRAYS--------DHDDRWETKEGAASPAPETPQ 383 Q K E R RR R + + A R S D+ D+ + + SP P P+ Sbjct: 170 REQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSP-PRPPR 228 Query: 384 PT----SPETSPKETPMQPPEI------------------PAPAHRPPEDEGEENEGEED 421 KE M+ ++ + A E EE E EE+ Sbjct: 229 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 288 Query: 422 EEWEDISEDEEEEEIEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEPQ 481 EE SE+ EEEE E EE +EE + +A E + + E + E LL Sbjct: 289 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV-- 346 Query: 482 APGTPSSPFSPPSGHQPVSDWGEEVELNSPRTTHLAGALSPGEAWP 527 P S F SG ++ EEV +P+++ AL+ G+ P Sbjct: 347 ---VPESRFDRDSGESEEAE--EEVGEGTPQSS----ALTEGDYVP 383 Score = 60.1 bits (144), Expect = 5e-09 Identities = 87/355 (24%), Positives = 140/355 (39%), Gaps = 65/355 (18%) Query: 159 RRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRR---RSGPLEESERDRREE 215 RR ++E EE + +A Q V + D+ R+ + ++E E +RR+ Sbjct: 68 RREDSMEDRGEEDDSLAIKPPQQMS---RKEKVHHRKDEKRKEKWKHARVKEREHERRKR 124 Query: 216 SRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERS--EYLRWKQEREK 273 R E+ + E ERQ RR +M + RER E L K+ERE+ Sbjct: 125 HRE----------EQDKARREWERQKRR-------EMAREHSRRERDRLEQLERKRERER 167 Query: 274 IDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHR--YDDQA----WAR-PPK 326 +E+ + R+ + RR + K ++ V AH + R Y D+ W+R PP+ Sbjct: 168 KMREQQKEQREQKERERRAEERRKEREARRE--VSAHHRTMREDYSDKVKASHWSRSPPR 225 Query: 327 PPT----FGEFLSQHKAEASSRR------------RRKSSRPQAKAAPRAYSDHDDRWET 370 PP G+ K E R RK+S ++ +A ++ E Sbjct: 226 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 285 Query: 371 KEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISED 430 +E E TS E+ +E + E ++ +E E EE E E++SED Sbjct: 286 EE------EEEEGSTSEESEEEEEEEEEEEEETGSN---SEEASEQSAEEVSE-EEMSED 335 Query: 431 EEEEE-----IEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEP 480 EE E + E + + + +A E G P S + P+ P L P Sbjct: 336 EERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLP 390 >gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9 [Homo sapiens] Length = 771 Score = 67.4 bits (163), Expect = 3e-11 Identities = 99/405 (24%), Positives = 154/405 (38%), Gaps = 73/405 (18%) Query: 157 EERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPL--EESERDRRE 214 E++RR+ E+ E +R+ + LE +R+ + R+ P E+S DR E Sbjct: 19 EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGE 78 Query: 215 ESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRWKQEREKI 274 E P + R H R+ + R+ ++ R K++ Sbjct: 79 EDDSLAIK---PPQQMSRKEKVHHRKDEK---------------RKEKKHARVKEKER-- 118 Query: 275 DQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEFL 334 + ER +RHR+ + RREW+ +K M A E S R D+ K + Sbjct: 119 EHERRKRHREEQDKARREWERQKRREM-------AREHSRRERDRLEQLERKRERERKMR 171 Query: 335 SQHKA--EASSRRRRKSSRPQAKAAPRAYS--------DHDDRWETKEGAASPAPETPQP 384 Q K E R RR R + + A R S D+ D+ + + SP P P+ Sbjct: 172 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSP-PRPPRE 230 Query: 385 T----SPETSPKETPMQPPEI------------------PAPAHRPPEDEGEENEGEEDE 422 KE M+ ++ + A E EE E EE+E Sbjct: 231 RFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE 290 Query: 423 EWEDISEDEEEEEIEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEPQA 482 E SE+ EEEE E EE +EE + +A E + + E + E LL Sbjct: 291 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV--- 347 Query: 483 PGTPSSPFSPPSGHQPVSDWGEEVELNSPRTTHLAGALSPGEAWP 527 P S F SG ++ EEV +P+++ AL+ G+ P Sbjct: 348 --VPESRFDRDSGESEEAE--EEVGEGTPQSS----ALTEGDYVP 384 Score = 65.9 bits (159), Expect = 9e-11 Identities = 87/352 (24%), Positives = 138/352 (39%), Gaps = 58/352 (16%) Query: 159 RRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESERDRREESRR 218 RR ++E EE + +A Q V + D+ R+ E++R E R+ Sbjct: 68 RREDSMEDRGEEDDSLAIKPPQQMS---RKEKVHHRKDEKRKEKKHARVKEKEREHERRK 124 Query: 219 HGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERS--EYLRWKQEREKIDQ 276 R E+ + E ERQ RR +M + RER E L K+ERE+ + Sbjct: 125 RHRE------EQDKARREWERQKRR-------EMAREHSRRERDRLEQLERKRERERKMR 171 Query: 277 ERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHR--YDDQA----WAR-PPKPPT 329 E+ + R+ + RR + K ++ V AH + R Y D+ W+R PP+PP Sbjct: 172 EQQKEQREQKERERRAEERRKEREARRE--VSAHHRTMREDYSDKVKASHWSRSPPRPPR 229 Query: 330 ----FGEFLSQHKAEASSRR------------RRKSSRPQAKAAPRAYSDHDDRWETKEG 373 G+ K E R RK+S ++ +A ++ E +E Sbjct: 230 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE- 288 Query: 374 AASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEE 433 E TS E+ +E + E ++ +E E EE E E++SEDEE Sbjct: 289 -----EEEEGSTSEESEEEEEEEEEEEEETGSN---SEEASEQSAEEVSE-EEMSEDEER 339 Query: 434 EE-----IEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEP 480 E + E + + + +A E G P S + P+ P L P Sbjct: 340 ENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSP 391 >gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform 4 [Homo sapiens] Length = 737 Score = 66.2 bits (160), Expect = 7e-11 Identities = 94/378 (24%), Positives = 146/378 (38%), Gaps = 70/378 (18%) Query: 159 RRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESERDRREESRR 218 RR ++E EE + +A Q V + D+ R+ E++R E R+ Sbjct: 34 RREDSMEDRGEEDDSLAIKPPQQMS---RKEKVHHRKDEKRKEKKHARVKEKEREHERRK 90 Query: 219 HGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERS--EYLRWKQEREKIDQ 276 R E+ + E ERQ RR +M + RER E L K+ERE+ + Sbjct: 91 RHRE------EQDKARREWERQKRR-------EMAREHSRRERDRLEQLERKRERERKMR 137 Query: 277 ERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHR--YDDQA----WAR-PPKPPT 329 E+ + R+ + RR + K ++ V AH + R Y D+ W+R PP+PP Sbjct: 138 EQQKEQREQKERERRAEERRKEREARRE--VSAHHRTMREDYSDKVKASHWSRSPPRPPR 195 Query: 330 FGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQPTSPET 389 + R+ K + + + D D A S + E+ + Sbjct: 196 ------ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS---- 245 Query: 390 SPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVEEGDEEEPAQD 449 E EE E EE+EE SE+ EEEE E EE +EE + Sbjct: 246 ----------------------EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 283 Query: 450 HQAPEAAPTGIPCSEQAHGVPFSPEEPLLEPQAPGTPSSPFSPPSGHQPVSDWGEEVELN 509 +A E + + E + E LL P S F SG ++ EEV Sbjct: 284 EEASEQSAEEVSEEEMSEDEERENENHLLV-----VPESRFDRDSGESEEAE--EEVGEG 336 Query: 510 SPRTTHLAGALSPGEAWP 527 +P+++ AL+ G+ P Sbjct: 337 TPQSS----ALTEGDYVP 350 >gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8 [Homo sapiens] Length = 780 Score = 65.1 bits (157), Expect = 2e-10 Identities = 93/380 (24%), Positives = 144/380 (37%), Gaps = 65/380 (17%) Query: 159 RRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESERDRREESRR 218 RR ++E EE + +A Q V + D+ R+ E++R E R+ Sbjct: 68 RREDSMEDRGEEDDSLAIKPPQQMS---RKEKVHHRKDEKRKEKKHARVKEKEREHERRK 124 Query: 219 HGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTG----RERSEYLRWKQEREKI 274 R E+ + E ERQ RR G R+R E L K+ERE+ Sbjct: 125 RHRE------EQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERK 178 Query: 275 DQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHR--YDDQA----WAR-PPKP 327 +E+ + R+ + RR + K ++ V AH + R Y D+ W+R PP+P Sbjct: 179 MREQQKEQREQKERERRAEERRKEREARRE--VSAHHRTMREDYSDKVKASHWSRSPPRP 236 Query: 328 PTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQPTSP 387 P + R+ K + + + D D A S + E+ + Sbjct: 237 PR------ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS-- 288 Query: 388 ETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVEEGDEEEPA 447 E EE E EE+EE SE+ EEEE E EE +EE + Sbjct: 289 ------------------------EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 324 Query: 448 QDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEPQAPGTPSSPFSPPSGHQPVSDWGEEVE 507 +A E + + E + E LL P S F SG ++ EEV Sbjct: 325 NSEEASEQSAEEVSEEEMSEDEERENENHLLV-----VPESRFDRDSGESEEAE--EEVG 377 Query: 508 LNSPRTTHLAGALSPGEAWP 527 +P+++ AL+ G+ P Sbjct: 378 EGTPQSS----ALTEGDYVP 393 >gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform 2 [Homo sapiens] Length = 782 Score = 65.1 bits (157), Expect = 2e-10 Identities = 100/413 (24%), Positives = 159/413 (38%), Gaps = 78/413 (18%) Query: 157 EERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPL--EESERDRRE 214 E++RR+ E+ E +R+ + LE +R+ + R+ P E+S DR E Sbjct: 19 EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGE 78 Query: 215 ES--------RRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLR 266 E ++ R E+V + +R+ +R + E ++ R Sbjct: 79 EDDSLAIKPPQQMSRK------EKVHHRKDEKRKEKRRHRSHSA---------EGGKHAR 123 Query: 267 WKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPK 326 K++ + ER +RHR+ + RREW+ +K M A E S R D+ K Sbjct: 124 VKEKER--EHERRKRHREEQDKARREWERQKRREM-------AREHSRRERDRLEQLERK 174 Query: 327 PPTFGEFLSQHKA--EASSRRRRKSSRPQAKAAPRAYS--------DHDDRWETKEGAAS 376 + Q K E R RR R + + A R S D+ D+ + + S Sbjct: 175 RERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRS 234 Query: 377 PAPETPQPT----SPETSPKETPMQPPEI------------------PAPAHRPPEDEGE 414 P P P+ KE M+ ++ + A E E Sbjct: 235 P-PRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 293 Query: 415 ENEGEEDEEWEDISEDEEEEEIEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPE 474 E E EE+EE SE+ EEEE E EE +EE + +A E + + E + E Sbjct: 294 EEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 353 Query: 475 EPLLEPQAPGTPSSPFSPPSGHQPVSDWGEEVELNSPRTTHLAGALSPGEAWP 527 LL P S F SG ++ EEV +P+++ AL+ G+ P Sbjct: 354 NHLLV-----VPESRFDRDSGESEEAE--EEVGEGTPQSS----ALTEGDYVP 395 Score = 60.8 bits (146), Expect = 3e-09 Identities = 89/355 (25%), Positives = 141/355 (39%), Gaps = 53/355 (14%) Query: 159 RRRQNIEKMNEEMEKIAEYERNQ--REGVLEPNPVRNFLDDPRRRSGPLEESERDR-REE 215 RR ++E EE + +A Q R+ + + R RS E + R +E+ Sbjct: 68 RREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEK 127 Query: 216 SRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERS--EYLRWKQEREK 273 R H R + E+ + E ERQ RR +M + RER E L K+ERE+ Sbjct: 128 EREHERRKRHRE-EQDKARREWERQKRR-------EMAREHSRRERDRLEQLERKRERER 179 Query: 274 IDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHR--YDDQA----WAR-PPK 326 +E+ + R+ + RR + K ++ V AH + R Y D+ W+R PP+ Sbjct: 180 KMREQQKEQREQKERERRAEERRKEREARRE--VSAHHRTMREDYSDKVKASHWSRSPPR 237 Query: 327 PPT----FGEFLSQHKAEASSRR------------RRKSSRPQAKAAPRAYSDHDDRWET 370 PP G+ K E R RK+S ++ +A ++ E Sbjct: 238 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 297 Query: 371 KEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISED 430 +E E TS E+ +E + E ++ +E E EE E E++SED Sbjct: 298 EE------EEEEGSTSEESEEEEEEEEEEEEETGSN---SEEASEQSAEEVSE-EEMSED 347 Query: 431 EEEEE-----IEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEP 480 EE E + E + + + +A E G P S + P+ P L P Sbjct: 348 EERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSP 402 >gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] Length = 780 Score = 63.5 bits (153), Expect = 4e-10 Identities = 99/405 (24%), Positives = 152/405 (37%), Gaps = 64/405 (15%) Query: 157 EERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPL--EESERDRRE 214 E++RR+ E+ E +R+ + LE +R+ + R+ P E+S DR E Sbjct: 19 EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGE 78 Query: 215 ESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRWKQEREKI 274 E P + R H R+ + E ++ R K+ Sbjct: 79 EDDSLAIK---PPQQMSRKEKVHHRKDEKR----KEKCRHHSHSAEGGKHARVKER---- 127 Query: 275 DQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEFL 334 + ER +RHR+ + RREW+ +K M A E S R D+ K + Sbjct: 128 EHERRKRHREEQDKARREWERQKRREM-------AREHSRRERDRLEQLERKRERERKMR 180 Query: 335 SQHKA--EASSRRRRKSSRPQAKAAPRAYS--------DHDDRWETKEGAASPAPETPQP 384 Q K E R RR R + + A R S D+ D+ + + SP P P+ Sbjct: 181 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSP-PRPPRE 239 Query: 385 T----SPETSPKETPMQPPEI------------------PAPAHRPPEDEGEENEGEEDE 422 KE M+ ++ + A E EE E EE+E Sbjct: 240 RFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE 299 Query: 423 EWEDISEDEEEEEIEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEPQA 482 E SE+ EEEE E EE +EE + +A E + + E + E LL Sbjct: 300 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV--- 356 Query: 483 PGTPSSPFSPPSGHQPVSDWGEEVELNSPRTTHLAGALSPGEAWP 527 P S F SG ++ EEV +P+++ AL+ G+ P Sbjct: 357 --VPESRFDRDSGESEEAE--EEVGEGTPQSS----ALTEGDYVP 393 Score = 59.3 bits (142), Expect = 8e-09 Identities = 84/367 (22%), Positives = 135/367 (36%), Gaps = 71/367 (19%) Query: 142 GAGDTSISDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRR 201 G D S++ + ++ + + + K + EK + + G R + RR Sbjct: 77 GEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGG----KHARVKEREHERR 132 Query: 202 SGPLEESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRER 261 EE ++ RRE R+ R R R LE + R RER Sbjct: 133 KRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRE---------------RER 177 Query: 262 SEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHR--YDDQ 319 + K++RE+ ++ER R+ + RRE V AH + R Y D+ Sbjct: 178 KMREQQKEQREQKERERRAEERRKEREARRE--------------VSAHHRTMREDYSDK 223 Query: 320 A----WAR-PPKPPT----FGEFLSQHKAEASSRR------------RRKSSRPQAKAAP 358 W+R PP+PP G+ K E R RK+S ++ +A Sbjct: 224 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAE 283 Query: 359 RAYSDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEG 418 ++ E +E E TS E+ +E + E ++ +E E Sbjct: 284 SGSGSEEEEEEEEE------EEEEGSTSEESEEEEEEEEEEEEETGSN---SEEASEQSA 334 Query: 419 EEDEEWEDISEDEEEEE-----IEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSP 473 EE E E++SEDEE E + E + + + +A E G P S + P Sbjct: 335 EEVSE-EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVP 393 Query: 474 EEPLLEP 480 + P L P Sbjct: 394 DSPALLP 400 >gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform 5 [Homo sapiens] Length = 748 Score = 62.0 bits (149), Expect = 1e-09 Identities = 77/291 (26%), Positives = 115/291 (39%), Gaps = 52/291 (17%) Query: 269 QEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPP 328 +E+E+ + ER +RHR+ + RREW+ +K M A E S R D+ K Sbjct: 91 KEKER-EHERRKRHREEQDKARREWERQKRREM-------AREHSRRERDRLEQLERKRE 142 Query: 329 TFGEFLSQHKA--EASSRRRRKSSRPQAKAAPRAYS--------DHDDRWETKEGAASPA 378 + Q K E R RR R + + A R S D+ D+ + + SP Sbjct: 143 RERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSP- 201 Query: 379 PETPQPT----SPETSPKETPMQPPEI------------------PAPAHRPPEDEGEEN 416 P P+ KE M+ ++ + A E EE Sbjct: 202 PRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEE 261 Query: 417 EGEEDEEWEDISEDEEEEEIEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEP 476 E EE+EE SE+ EEEE E EE +EE + +A E + + E + E Sbjct: 262 EEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENH 321 Query: 477 LLEPQAPGTPSSPFSPPSGHQPVSDWGEEVELNSPRTTHLAGALSPGEAWP 527 LL P S F SG ++ EEV +P+++ AL+ G+ P Sbjct: 322 LLV-----VPESRFDRDSGESEEAE--EEVGEGTPQSS----ALTEGDYVP 361 Score = 60.8 bits (146), Expect = 3e-09 Identities = 89/355 (25%), Positives = 141/355 (39%), Gaps = 53/355 (14%) Query: 159 RRRQNIEKMNEEMEKIAEYERNQ--REGVLEPNPVRNFLDDPRRRSGPLEESERDR-REE 215 RR ++E EE + +A Q R+ + + R RS E + R +E+ Sbjct: 34 RREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEK 93 Query: 216 SRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERS--EYLRWKQEREK 273 R H R + E+ + E ERQ RR +M + RER E L K+ERE+ Sbjct: 94 EREHERRKRHRE-EQDKARREWERQKRR-------EMAREHSRRERDRLEQLERKRERER 145 Query: 274 IDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHR--YDDQA----WAR-PPK 326 +E+ + R+ + RR + K ++ V AH + R Y D+ W+R PP+ Sbjct: 146 KMREQQKEQREQKERERRAEERRKEREARRE--VSAHHRTMREDYSDKVKASHWSRSPPR 203 Query: 327 PPT----FGEFLSQHKAEASSRR------------RRKSSRPQAKAAPRAYSDHDDRWET 370 PP G+ K E R RK+S ++ +A ++ E Sbjct: 204 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 263 Query: 371 KEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISED 430 +E E TS E+ +E + E ++ +E E EE E E++SED Sbjct: 264 EE------EEEEGSTSEESEEEEEEEEEEEEETGSN---SEEASEQSAEEVSE-EEMSED 313 Query: 431 EEEEE-----IEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEP 480 EE E + E + + + +A E G P S + P+ P L P Sbjct: 314 EERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSP 368 >gi|4503509 eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa [Homo sapiens] Length = 1382 Score = 59.3 bits (142), Expect = 8e-09 Identities = 113/483 (23%), Positives = 174/483 (36%), Gaps = 67/483 (13%) Query: 7 LKSKEEKD-AELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRSVEKEN 65 LK +EE++ AE KR E LR E +++ +E+E +++ ELE +E+ Sbjct: 823 LKEREERERAERAKREEELREYQER-VKKLEEVERKKRQRELE------------IEERE 869 Query: 66 VAVESEKNLGPS-----------RRSPGTPR--PPGASKGGRTPPQQGGRAGMGRASRSW 112 E E+ LG S R S GT R P S+ R PP++ R G GR Sbjct: 870 RRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRS 929 Query: 113 EGSPGEQPRGGGAGGRGR--------RGRGRGSPHLSGAGDTSISDRKSKEWEERRRQNI 164 E+PR G R RG G DR S+ + R + Sbjct: 930 HRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSW 989 Query: 165 EKMNEEM--EKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESERDRREESRRHGRN 222 +++ +IA+ +R + P R LD+ R +E RR G Sbjct: 990 RNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPR 1049 Query: 223 WGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRH 282 GG D ER + +G R GL D G + R + ++ + + Sbjct: 1050 RGGADDERSSWRNADDDRGPRRGL---DDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDD 1106 Query: 283 RKP-------TGQWRREWD-------AEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPP 328 R P G WR D AE G +++ + S R DD + R Sbjct: 1107 RGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRN--MDDDRLSRRADDDRFPRRGDDS 1164 Query: 329 TFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDR-WE-TKEGAASPAPETPQPTS 386 G + + + R ++ +R ++ PR ++R W+ KE Sbjct: 1165 RPGPW--RPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKD 1222 Query: 387 PETSPKETPMQPPEIPAPAHRPPEDEGEENEG--EEDEEWEDIS--EDEEEEEIEVEEGD 442 PE +E + R P DEG G EE W D S +D + ++ E D Sbjct: 1223 PE---RERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDD 1279 Query: 443 EEE 445 + Sbjct: 1280 RRD 1282 Score = 47.0 bits (110), Expect = 4e-05 Identities = 96/462 (20%), Positives = 162/462 (35%), Gaps = 60/462 (12%) Query: 26 RKNEALIRRYQEIEEDRKKAELEGVAVTAPRKG--------RSVEKENVAVESEKNLGPS 77 R++E RR + +EDR+ + L PR+G R E++ + + PS Sbjct: 931 RRDEERPRRLGD-DEDREPS-LRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPS 988 Query: 78 RRSPGTPRPP----GASKGG--RTPPQQGGRAGMGRASRSWEGSPGEQ-PRGGGAGGRGR 130 R+ RPP +G + R G+ SW + ++ PR G RG Sbjct: 989 WRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGP 1048 Query: 131 RGRGRGSPHLSGAG-DTSISDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPN 189 R G S D R+ + + R+ ++ + + + +R R G+ + Sbjct: 1049 RRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDD-DRGPRRGMDDDRGPRRGMDDDR 1107 Query: 190 PVRNFLDDPRRRSGPLEESERDR--REESRRHGRNWGGPDFERVRCGLEHERQGRRAG-- 245 R LDD R GP ++ DR R + W D +R+ + +R RR Sbjct: 1108 GPRRGLDDDR---GPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDS 1164 Query: 246 -------LGSAGDMTLSMTGRERS----------EYLRW--KQEREKIDQERLQRHRKPT 286 L G RE S E W ++ER++ +Q+R + + P Sbjct: 1165 RPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPE 1224 Query: 287 GQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPP--KPPTFGEFLSQHKAEASSR 344 + RE D ++ D + D+ W R P + ++ + + + R Sbjct: 1225 RERDRERDVDREDRFRRPR-----------DEGGWRRGPAEESSSWRDSSRRDDRDRDDR 1273 Query: 345 RRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAP 404 RR + R + D D R + + E P +P P Sbjct: 1274 RRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPP 1333 Query: 405 A--HRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVEEGDEE 444 A D E EGE+++ +D E E DE+ Sbjct: 1334 ALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETDED 1375 Score = 43.1 bits (100), Expect = 6e-04 Identities = 64/303 (21%), Positives = 106/303 (34%), Gaps = 61/303 (20%) Query: 156 WEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESERDRREE 215 +EE+ +Q E++ EE E + QR+ R ++ +RR+ ER+ RE Sbjct: 772 YEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERER 831 Query: 216 SRRHGRNWGGPDF-ERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRWKQEREKI 274 + R R ++ ERV+ E ER+ R+ L E E R ++E ++ Sbjct: 832 AERAKREEELREYQERVKKLEEVERKKRQREL-------------EIEERERRREEERRL 878 Query: 275 DQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEFL 334 L R W ++G ++ GP D W R P + Sbjct: 879 GDSSLSRKDS-------RWGDRDSEGTWRKGPEA---------DSEWRRGPPEKEWRR-- 920 Query: 335 SQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQPTSPETSPKE- 393 + + E S RR + PR D +DR P P + Sbjct: 921 GEGRDEDRSHRRDEE-------RPRRLGDDEDR------------------EPSLRPDDD 955 Query: 394 -TPMQPPEIPAPAHRPPEDEGEENEGEEDE--EWEDISEDEEEEEIEVEEGDEEEPAQDH 450 P + + R PE++ G +D+ W + +D I E+ A D Sbjct: 956 RVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDD 1015 Query: 451 QAP 453 + P Sbjct: 1016 RPP 1018 Score = 38.9 bits (89), Expect = 0.012 Identities = 47/184 (25%), Positives = 70/184 (38%), Gaps = 19/184 (10%) Query: 152 KSKEWE-ERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESER 210 + +EW+ E+ R + EE +K E ER++ V + R D+ R GP EES Sbjct: 1199 EEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESS- 1257 Query: 211 DRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRWKQE 270 R+ SRR R+ ER ER+ R G S ER E W++ Sbjct: 1258 SWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRS----EREEVSSWRRA 1313 Query: 271 REKID---QER----------LQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYD 317 ++ D +ER L R R+ RE + EK + + D Sbjct: 1314 DDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETD 1373 Query: 318 DQAW 321 + W Sbjct: 1374 EDGW 1377 Score = 32.7 bits (73), Expect = 0.85 Identities = 68/332 (20%), Positives = 126/332 (37%), Gaps = 50/332 (15%) Query: 148 ISDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNP-VRNFLDDPRRRSGPLE 206 I ++ ++ E+ +++ E++ + +KI +ER +R LE P +++ ++ R + L Sbjct: 669 IMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKR---LEEIPLIKSAYEEQRIKDMDLW 725 Query: 207 ESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYL- 265 E + + R + + ER + LEH+ + R L + + +S Y Sbjct: 726 EQQEEERITTMQ---------LEREKA-LEHKNRMSRM-LEDRDLFVMRLKAARQSVYEE 774 Query: 266 RWKQEREKIDQER---LQRHRKPTGQWRR---------EWDAEKTDGMFKDGPVPAHEPS 313 + KQ E++ +ER L+ ++ + RR E + M K+ Sbjct: 775 KLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAER 834 Query: 314 HRYDDQA---WARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWET 370 + +++ R K Q + E R RR+ + + + S D RW Sbjct: 835 AKREEELREYQERVKKLEEVERKKRQRELEIEERERRREE--ERRLGDSSLSRKDSRWGD 892 Query: 371 K--EGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDIS 428 + EG PE + E PPE R E E+ DEE Sbjct: 893 RDSEGTWRKGPE---------ADSEWRRGPPE---KEWRRGEGRDEDRSHRRDEERPRRL 940 Query: 429 EDEEEEEIEVEEGDEEEPAQ---DHQAPEAAP 457 D+E+ E + D+ P + D + P P Sbjct: 941 GDDEDREPSLRPDDDRVPRRGMDDDRGPRRGP 972 >gi|50962882 G patch domain containing 8 [Homo sapiens] Length = 1502 Score = 59.3 bits (142), Expect = 8e-09 Identities = 122/612 (19%), Positives = 196/612 (32%), Gaps = 144/612 (23%) Query: 7 LKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRSVEKENV 66 L SK+E+ + + + + K + +R + + + K ++ E + RK R +K Sbjct: 662 LPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKS 721 Query: 67 AVESEKNLGPSRRSPGTPRPPGASKGGRTPPQQGGRA---GMGRASRSWEGSPGEQPRGG 123 + ++ GP PG+ G PP++ RA R+ + EGS G++ GG Sbjct: 722 SAPADSERGPKPEPPGS--------GSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGG 773 Query: 124 GA------GGRGRRG--------------RGRGSPHLS--GAGDTSISDRKSKEWEERRR 161 G GGR +G R S H S +GD D S ++ Sbjct: 774 GGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSP 833 Query: 162 QNIEKMNEEMEKIAEYERNQ-------------------------------REGVLEPNP 190 + EE + +E+ R++ R+ + Sbjct: 834 SQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDS 893 Query: 191 VRNFLDDPRRRSGPLEESE----RDRREESRRHGRNWGGPDF------ERVRCGLEHERQ 240 ++ D RR S +S+ + S+RH + D+ R R + Sbjct: 894 YSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRER 953 Query: 241 GRRAGLGSAGDMTLSMT-GRERSEYLRWKQEREKIDQERLQRHRKP---TGQWRREWDAE 296 R G + + S + R RS Q ++R + R P +G +R W E Sbjct: 954 SRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHE 1013 Query: 297 KTDGMFKD----------------------GPVPAHEPSHRYDDQAWARPPKPPTFGEFL 334 + G P + R DD PP Sbjct: 1014 SPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPP--------- 1064 Query: 335 SQHKAEASSRRRRKSSRPQAKAAPRA----YSDHDDRWETKEGAASPAPETPQPTSPETS 390 SQ+ + R P+ K + A + E K + TP P+ Sbjct: 1065 SQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLK 1124 Query: 391 PKETPMQPPEIP--------------APAHRPPEDEGEENEGEEDEEWEDISEDEEEEEI 436 P++P PA R P + EE+ + EE+E+ Sbjct: 1125 DPPQGYFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEES---------GLERGEEQEQS 1175 Query: 437 EVEEG--DEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEPQAP-GTPSS----P 489 E EEG + HQ P TG P + S E P AP GTP+ P Sbjct: 1176 ETEEGPPGSSDALFGHQFPSEETTG-PLLDPPPEESKSGEATADHPVAPLGTPAHSDCYP 1234 Query: 490 FSPPSGHQPVSD 501 P H + D Sbjct: 1235 GDPTISHNYLPD 1246 Score = 31.6 bits (70), Expect = 1.9 Identities = 28/99 (28%), Positives = 39/99 (39%), Gaps = 10/99 (10%) Query: 6 DLKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRSVEKEN 65 DLK +E + R +K E +RR E+ E RK+AE AP G + Sbjct: 168 DLKQREFA-RNVSSRSRKDEKKQEKALRRLHELAEQRKQAE------CAPGSGPMFKPTT 220 Query: 66 VAVE---SEKNLGPSRRSPGTPRPPGASKGGRTPPQQGG 101 VAV+ E + S + GT G +GG Sbjct: 221 VAVDEEGGEDDKDESATNSGTGATASCGLGSEFSTDKGG 259 >gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 436 Score = 57.8 bits (138), Expect = 2e-08 Identities = 88/452 (19%), Positives = 166/452 (36%), Gaps = 36/452 (7%) Query: 11 EEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRSVEKENVAVES 70 +EK+AEL + ++ + + + +E+ K +LE + P++G+ E+E E Sbjct: 10 KEKNAELQEELQLVETEKSEIQLHIKEL-----KRKLETDKIPLPQEGQVREQEGQVREQ 64 Query: 71 EKNLGPSRRSPGTPRPPGASKGGRTPPQQGGRAGMGRASRSWEGSPGEQPRGGGAGGRGR 130 E G R G R + G+ Q+G R EG EQ G+ R Sbjct: 65 E---GQVREQEGQVR----EQEGQVREQEGQVREQEGQVREQEGQVREQE------GQVR 111 Query: 131 RGRGRGSPHLSGAGDTSISDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNP 190 G+ G + + +E E + R+ ++ E+ ++ E E RE + Sbjct: 112 EQEGQVREQ---EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE---QEGQ 165 Query: 191 VRNFLDDPRRRSGPLEESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAG 250 VR R + G + E E RE+ + G G + + G + E+ ++ Sbjct: 166 VREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225 Query: 251 DMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDA--EKTDGMFKDGPVP 308 + + + E Q++E+ Q++ ++ RK Q R + + E+ + M K Sbjct: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285 Query: 309 AHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRW 368 E ++ + E + + E + R+ K + + + W Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEE----QMREQEEQMGKQEEQMWEQKEQMW 341 Query: 369 ETKEGA------ASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDE 422 E KE E Q + +E M+ E + EE GE+ E Sbjct: 342 EQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKE 401 Query: 423 EWEDISEDEEEEEIEVEEGDEEEPAQDHQAPE 454 + + E E+E ++ E E+ Q+ E Sbjct: 402 QMGEQKEQMREQEEQMGEQKEQMRKQEEHMGE 433 >gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] Length = 1332 Score = 56.6 bits (135), Expect = 5e-08 Identities = 85/365 (23%), Positives = 131/365 (35%), Gaps = 56/365 (15%) Query: 159 RRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESERDRREESRR 218 +R++ IE+ EE ++ E +R +RE R + ++R LE+ + RREE RR Sbjct: 393 QRQRRIEEQKEERRRVEEQQRREREQ-------RKLQEKEQQRR--LEDMQALRREEERR 443 Query: 219 HGRNWGGPDFERVRCGLEHERQGRRAG--LGSAGDMTLSMTGRERSEYLRWKQEREKIDQ 276 + E R LE +RQ R L S+ +++ + L+ +Q+++ + Sbjct: 444 QAER----EQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPG 499 Query: 277 ERLQRHRKPTGQ-------WRREWDAEKTDGMFKDGPVPAHEPSHRYDD----QAWARPP 325 +R + G W RE + ++ P+ +P + QA PP Sbjct: 500 DRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPP 559 Query: 326 -----KPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPE 380 PP Q S R +P A PR+ S D T+ AA PA Sbjct: 560 GPLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQ--PTRNLAAFPASH 617 Query: 381 TPQPTSPETSPKETPMQ-----------PPEIPAPAHRPPEDEGEENEGEEDEEWEDISE 429 P P P +P TP E P P+ PP +NE S Sbjct: 618 DPDPAIP--APTATPSARGAVIRQNSDPTSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSI 675 Query: 430 DEEEEEIEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEPQAPGTPSSP 489 + PAQ +A P S A + P+ PG P+ P Sbjct: 676 ---ATALNTSGAGGSRPAQAVRAR-------PRSNSAWQIYLQRRAERGTPKPPGPPAQP 725 Query: 490 FSPPS 494 PP+ Sbjct: 726 PGPPN 730 Score = 35.0 bits (79), Expect = 0.17 Identities = 36/148 (24%), Positives = 53/148 (35%), Gaps = 21/148 (14%) Query: 78 RRSPGTPRPPGASKGGRTPPQQGGRAGMGRASRSWEGSPGEQPRGGG----AGG--RGRR 131 R GTP+PPG PP + R+ WE S P G AG R R Sbjct: 710 RAERGTPKPPGPPAQPPGPPNASSNPDLRRSDPGWERSDSVLPASHGHLPQAGSLERNRV 769 Query: 132 G---RGRGSPHLSGAGDTSISDRKSK-----EWEERRRQNIEKMNEEMEKIAEYERNQRE 183 G + SP LS D +S+ ++ + + +++ +K +Y + E Sbjct: 770 GVSSKPDSSPVLSPGNKAKPDDHRSRPGRPADFVLLKERTLDEAPRPPKKAMDYSSSSEE 829 Query: 184 GVLEPNPVRNFLDDPRRRSGPLEESERD 211 V + DD G E RD Sbjct: 830 -------VESSEDDEEEGEGGPAEGSRD 850 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 55.5 bits (132), Expect = 1e-07 Identities = 63/313 (20%), Positives = 129/313 (41%), Gaps = 29/313 (9%) Query: 150 DRKSKEWEERRRQNIEKMNEEMEKIAEYER--NQREGVLEPNPVRNFLDDPRRRSGPLEE 207 ++K ++ EER + E++ E+ E++ E E+ Q E + E +R + ++ EE Sbjct: 351 EQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIR----EREKKMREEEE 406 Query: 208 SERDRREESRRHGRN-WGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLR 266 + R++ E+ ++ N W + E++ ++ L + + E Sbjct: 407 TMREQEEKMQKQEENMWE-----------QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 455 Query: 267 WKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYD--DQAWARP 324 W+QE + DQE + K WR+E E+ D M++ + +D ++ W + Sbjct: 456 WEQEEKIRDQEEMWGQEKK--MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQD 513 Query: 325 PKPPTFGEFLSQHKA----EASSRRRRKSSRPQAKAAPRAYS-DHDDRWETKEGAASPAP 379 + E + + K E R +K+ + K + ++R +E Sbjct: 514 ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 573 Query: 380 ETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEE-WEDISEDEEEEEIEV 438 E + + +E M+ E E EE E++E+ WE ED+ +E+ E+ Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633 Query: 439 EEGDEEEPAQDHQ 451 ++EE Q+ + Sbjct: 634 -MWEQEEKMQEQE 645 Score = 50.1 bits (118), Expect = 5e-06 Identities = 63/320 (19%), Positives = 123/320 (38%), Gaps = 32/320 (10%) Query: 145 DTSISDRKSKEWE--ERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRS 202 + + +++ K WE E+ R+ EKM + E++ E E+ RE + + D R Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK-------MRDQEERM 361 Query: 203 GPLEESERDRREESRRHGRNWGGPDF----ERVRCGLEHERQGRRAGLGSAGDMTLSMTG 258 +E R++ E R + W + ER+R E E++ R M Sbjct: 362 WEQDERLREKEERMREQEKMWEQEEKMQEEERIR---EREKKMRE----EEETMREQEEK 414 Query: 259 RERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDD 318 ++ E W+QE ++ Q+RL ++ W +E E+ + +++ E R + Sbjct: 415 MQKQEENMWEQEEKEWQQQRLPEQKEKL--WEQEKMQEQEEKIWEQ------EEKIRDQE 466 Query: 319 QAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPA 378 + W + K + Q + + + + D+R KE Sbjct: 467 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ 526 Query: 379 PETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEG----EENEGEEDEEWEDISEDEEEE 434 + Q K+T Q + + E+E E+ EE+E + E +E+ Sbjct: 527 KKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ 586 Query: 435 EIEVEEGDEEEPAQDHQAPE 454 E ++ E +E+ Q+ + E Sbjct: 587 EEKMREQEEKMWEQEEKMQE 606 Score = 48.5 bits (114), Expect = 1e-05 Identities = 63/330 (19%), Positives = 125/330 (37%), Gaps = 35/330 (10%) Query: 150 DRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESE 209 + + +E EE+ + EKM E+ EK+ E E + + D R +E Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 368 Query: 210 RDRREESRRHGRNWGG----PDFERVR---CGLEHERQGRRAGLGSAGDMTLSMTGRERS 262 R++ E R + W + ER+R + E + R +M +E Sbjct: 369 REKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 428 Query: 263 EYLR----------WKQER-----EKI--DQERLQRHRKPTGQ----WRREWDAEKTDGM 301 E+ + W+QE+ EKI +E+++ + GQ WR+E E+ D M Sbjct: 429 EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM 488 Query: 302 FKDGPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAY 361 ++ E + + W + + E L + + +++ + + + Sbjct: 489 WEQ-----EEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQ 543 Query: 362 SDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEED 421 W+ +E E + + +E M+ E E EE E++ Sbjct: 544 EQEKKTWDQEEKMRE--EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE 601 Query: 422 EEWEDISEDEEEEEIEVEEGDEEEPAQDHQ 451 E+ ++ E E+E ++ E +EE+ Q+ + Sbjct: 602 EKMQEQEEKMWEQEEKMWEQEEEDKMQEQE 631 Score = 43.9 bits (102), Expect = 4e-04 Identities = 64/317 (20%), Positives = 114/317 (35%), Gaps = 67/317 (21%) Query: 145 DTSISDRKSKEW--EERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRS 202 + I ++ K W EER R+ KM E+ EK+ E+ RE E Sbjct: 247 EKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKE--------------- 291 Query: 203 GPLEESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERS 262 L E E++ RE+ + + E + Q + + + RE+ Sbjct: 292 --LREQEKELREQKKLREQ--------------EEQMQEQEEKMWEQEEKM-----REQE 330 Query: 263 EYLRWKQEREKIDQERLQR--HRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQA 320 E + W+QE +QE+ R +K Q R W+ +D + E R ++ Sbjct: 331 EKM-WRQEERLWEQEKQMREQEQKMRDQEERMWE--------QDERLREKEERMREQEKM 381 Query: 321 WARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPE 380 W + K + + ++ R+ + + ++ WE +E E Sbjct: 382 WEQEEK------MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE------KE 429 Query: 381 TPQPTSPETSPK---ETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEI- 436 Q PE K + MQ E + EE G+E + W E+E+++ Sbjct: 430 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 489 Query: 437 --EVEEGDEEEPAQDHQ 451 E + D+E+ D + Sbjct: 490 EQEEKMRDQEQKMWDQE 506 Score = 43.5 bits (101), Expect = 5e-04 Identities = 59/311 (18%), Positives = 117/311 (37%), Gaps = 20/311 (6%) Query: 150 DRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNF-----LDDPRRRSGP 204 ++K +E EE R+ EKM ++ E + E E + + P + + + Sbjct: 398 EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE 457 Query: 205 LEESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEY 264 EE RD+ E + + W + + + R D M E+ E Sbjct: 458 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMW--EQDER 515 Query: 265 LRWKQEREKID------QERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDD 318 LR K+ER + +E+++ +K Q ++ WD E+ M ++ + E R ++ Sbjct: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEK--MREEERMREREKKMREEE 573 Query: 319 QAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYS----DHDDRWETKEGA 374 + + E + + E + K + K + + +D+ + +E Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633 Query: 375 ASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEE 434 E Q + +E M+ E + + +G+E + E EE E++ E Sbjct: 634 MWEQEEKMQEQEEKMWEQEEKMREQE-EKMREQEEKMQGQEEKMREQEEKMQGQEEKMRE 692 Query: 435 EIEVEEGDEEE 445 + E G EE+ Sbjct: 693 QEEKMRGQEEK 703 Score = 38.9 bits (89), Expect = 0.012 Identities = 78/467 (16%), Positives = 162/467 (34%), Gaps = 82/467 (17%) Query: 7 LKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRSVEKENV 66 L+ KEE+ E +K E E ++ + I E KK E + + ++EN+ Sbjct: 368 LREKEERMREQEKMWE-----QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 422 Query: 67 AVESEKNLGPSRRSPGTPRPPGASKGGRTPPQQGGRAGMGRASRSWEGSP---GEQPRGG 123 + EK R P K Q + + WE ++ G Sbjct: 423 WEQEEKEWQQQRL------PEQKEKLWEQEKMQE------QEEKIWEQEEKIRDQEEMWG 470 Query: 124 GAGGRGRRGRGRGSPHLSGAGDTSISDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQRE 183 R+ + R + + D++ K W++ E+M E+ E++ E E RE Sbjct: 471 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE-----ERMWEQDERLREKEERMRE 525 Query: 184 GVLEPNPVRNFLDDPRRRSGPLEESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRR 243 +++ EE R+ ++ + + W + R E + R Sbjct: 526 ---------------QKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE----EERMRERE 566 Query: 244 AGLGSAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRRE---WDAEKTDG 300 + +M + + + + +++ EK+ ++ + + W +E W+ E+ D Sbjct: 567 KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDK 626 Query: 301 MFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRA 360 M ++ W + K Q + E + K + K Sbjct: 627 M------------QEQEEMMWEQEEK--------MQEQEEKMWEQEEKMREQEEKMR--- 663 Query: 361 YSDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEE 420 + +++ + +E E Q + +E M+ E + E+ G+E Sbjct: 664 --EQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQE------EKMWGQEEKMWGQE 715 Query: 421 DEEWEDISEDEEEEEIEVEEGDEEEPAQDHQ----APEAAPTGIPCS 463 ++ W E+EE I ++ +E +H+ P P+ + C+ Sbjct: 716 EKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSKVLCN 762 Score = 35.0 bits (79), Expect = 0.17 Identities = 35/188 (18%), Positives = 71/188 (37%), Gaps = 15/188 (7%) Query: 267 WKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPK 326 W+QE E +QE+ R ++ WR+E + +G ++ R +Q Sbjct: 237 WRQEEELREQEKKIRKQEEK-MWRQEERLREQEGKMREQEEKMRRQEKRLREQE------ 289 Query: 327 PPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQPTS 386 + L + + E +++ + Q + + +++ +E E Sbjct: 290 -----KELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344 Query: 387 PETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVEE---GDE 443 + +E M+ E E EE E+++ WE + +EEE I E +E Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREE 404 Query: 444 EEPAQDHQ 451 EE ++ + Sbjct: 405 EETMREQE 412 >gi|17975763 myelin transcription factor 1 [Homo sapiens] Length = 1121 Score = 55.5 bits (132), Expect = 1e-07 Identities = 41/109 (37%), Positives = 58/109 (53%), Gaps = 5/109 (4%) Query: 384 PTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVEEGDE 443 P S E + E + I + E+E EE E EEDEE E+ E+EEEEE E EE +E Sbjct: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEE-EEEEEEEEEEEEEEEE 295 Query: 444 EEPAQDHQAPEAAPTGIPCSEQAH-GVPFSPEEPLLEPQAPGTPSSPFS 491 EE ++ + EAAP I + +H +PE L P++P +P +S Sbjct: 296 EEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPE--LRGPESP-SPKPEYS 341 Score = 42.0 bits (97), Expect = 0.001 Identities = 43/153 (28%), Positives = 62/153 (40%), Gaps = 15/153 (9%) Query: 369 ETKEGAASPA--------PETPQPTSPETSPKETPMQPPEIP-APAHRPPEDEGEENEGE 419 E EGAAS PE + T+ + + P + A + + +G + E Sbjct: 200 EAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEE 259 Query: 420 EDEEWEDISEDEEE--EEIEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPL 477 EDEE E+ E+EEE EE E EE +EEE ++ + E E A V F + Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSH 319 Query: 478 LEPQAPGTPSSPFSPPSGHQPVSDWGEEVELNS 510 Q P SP P ++ VE+ S Sbjct: 320 TSAQKAPELRGPESP----SPKPEYSVIVEVRS 348 Score = 30.0 bits (66), Expect = 5.5 Identities = 26/112 (23%), Positives = 42/112 (37%), Gaps = 6/112 (5%) Query: 358 PRAYSDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENE 417 P++ D +K+ E + E +E + E E+E EE E Sbjct: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 296 Query: 418 GEEDEEWEDISEDEEEEEIEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGV 469 EE+EE E+E ++ +E AQ +APE P + + V Sbjct: 297 EEEEEE----EEEEAAPDVIFQEDTSHTSAQ--KAPELRGPESPSPKPEYSV 342 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 55.1 bits (131), Expect = 2e-07 Identities = 111/519 (21%), Positives = 171/519 (32%), Gaps = 56/519 (10%) Query: 41 DRKKAELEGV-AVTAPRKGRSVEKENVAVESEKNLGPSRRSPGTPRPPGASKGGRTPPQQ 99 D+ + +G + AP + E+ VE+ + G ++ + G +P S+ P + Sbjct: 1823 DQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPE--SEDVEAPEAE 1880 Query: 100 GGRAGMGRASRSWEGSPGEQPRGGGAGGRGRRGRGRGSPHLSGAGDTSISDRKSKEWEER 159 G + E QP GA + A +T D E E Sbjct: 1881 GEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEA 1940 Query: 160 RR-----QNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESERDRRE 214 + Q E + ++ E + + E E V +E ++ Sbjct: 1941 QEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEAL---------EVEVETQEAEG 1991 Query: 215 ESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRWKQEREKI 274 E++ + P+ E E E Q G+ + G E E Q+ E Sbjct: 1992 EAQPESEDVEAPEAEGEMQEAEEEAQPESDGV----EAQPKSEGEEAQEVEGETQKTEGD 2047 Query: 275 DQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEFL 334 Q P E +A++ +G ++ AH S D Q +P + G Sbjct: 2048 AQPESDGVEAPEA----EEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEA 2103 Query: 335 SQHKAEASSRRRRKSSRPQAKA--------APRAYSDHDDRWE-----TKEGAASPAPE- 380 + + EA ++ + +A AP A + E EG A P E Sbjct: 2104 PEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEG 2163 Query: 381 -TPQPTSPETSPKETPMQPPEIPAPAHRPPEDEG---EENEGEEDEEWEDISEDEEEEEI 436 Q E P+ ++ PE A PE EG E EGE E E + E EEE Sbjct: 2164 IEAQEAEEEAQPELEGVEAPEAEGEAQ--PESEGIEAPEAEGEAQPELEGVEAPEAEEEA 2221 Query: 437 EVE-EGDEEEPAQDHQAPEA--APTGIPCSEQAHGVPFSPEEPLLEPQAPGTPSSPFSPP 493 + E EG E A+ PE+ G + E E +P P PP Sbjct: 2222 QPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPP 2281 Query: 494 S--GHQPVSDWGEEVELNSPRTTHLAGALSPGEAWPFES 530 S G P G + +S R A S G W +S Sbjct: 2282 SPGGDTPHQRPGSQTGPSSSR------ASSWGNCWQKDS 2314 Score = 53.9 bits (128), Expect = 4e-07 Identities = 103/494 (20%), Positives = 166/494 (33%), Gaps = 62/494 (12%) Query: 39 EEDRKKAELEGVAVTAPRKGRSVEKENVAVESEKNLGPSRRSPGTPRPPGASKGGRTPPQ 98 ++D K E EG A+ R+G++ E A LG + + G S+ G T Q Sbjct: 1755 DKDPKLGEAEGDAMAQEREGKTHNSETSA---GSELGEAEQEG-----EGISERGETGGQ 1806 Query: 99 QGGRAG--MGRASRSWEGSPGEQPRGGGAGGRGRRGRGRGSPHLSGAGDTSISDRKSKEW 156 G G A+ + PG+ G G G P G E Sbjct: 1807 GSGHEDNLQGEAAAGGDQDPGQSD--GAEGIEAPEAEGEAQPESEGV-----------EA 1853 Query: 157 EERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESERDRREES 216 E E E + + E + EG E P ++ P ESE E+ Sbjct: 1854 PEAEGDAQEAEGEAQPESEDVEAPEAEG--EAQPESEDVETPEAEWEVQPESEGAEAPEA 1911 Query: 217 RRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRWKQEREKIDQ 276 + + P+ E V LE E + G+ QE E+ Q Sbjct: 1912 EKEAQ----PETESVEA-LETEGEDEPESEGAEA------------------QEAEEAAQ 1948 Query: 277 ERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQ 336 E + +P + +AE+ + + V A E + P+ E + Sbjct: 1949 EA-EGQTQPESEVIESQEAEE-EAQPESEDVEALEVEVETQEAEGEAQPE----SEDVEA 2002 Query: 337 HKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQPTSPETSPKETPM 396 +AE + + ++P++ + + EG +T PE+ E P Sbjct: 2003 PEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQ---KTEGDAQPESDGVEAPE 2059 Query: 397 QPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVEEGDEEEPAQDHQAPEAA 456 E E EGE + ED + ++ + + E VE + E AQ + EA Sbjct: 2060 AEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAP 2119 Query: 457 PTGIPCSEQAHGVPFSPEEPLLEPQAPGTPSSPFSPPSGHQPVSDWGEEVELNSPRTTHL 516 T ++ G+ E +P++ G + + QP S+ E E L Sbjct: 2120 ETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEA--QPESEGIEAQEAEEEAQPEL 2177 Query: 517 AGALSP---GEAWP 527 G +P GEA P Sbjct: 2178 EGVEAPEAEGEAQP 2191 Score = 33.9 bits (76), Expect = 0.38 Identities = 35/142 (24%), Positives = 56/142 (39%), Gaps = 6/142 (4%) Query: 335 SQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQPTSPETSPKET 394 ++ +AE S +R SS + + A + ETKEG + ET +E Sbjct: 1272 NEDEAERDSEEQRASSNLE-QLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEG 1330 Query: 395 PMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEE----IEVEEGDEEEPAQDH 450 +Q + + E EG++ E + EE E+ + +EE EV+EG E + Sbjct: 1331 -LQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEA 1389 Query: 451 QAPEAAPTGIPCSEQAHGVPFS 472 G+P HG S Sbjct: 1390 LEEGLKEEGLPEEGSVHGQELS 1411 >gi|55956788 nucleolin [Homo sapiens] Length = 710 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 2/98 (2%) Query: 354 AKAAPRAYSDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEG 413 A AAP + + D+ E E + + + ET+P + +P A EDE Sbjct: 178 AAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDED 237 Query: 414 EE--NEGEEDEEWEDISEDEEEEEIEVEEGDEEEPAQD 449 EE +E E+D++ ED +D++E++ E EE +EEEP ++ Sbjct: 238 EEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKE 275 Score = 48.1 bits (113), Expect = 2e-05 Identities = 46/177 (25%), Positives = 73/177 (41%), Gaps = 15/177 (8%) Query: 295 AEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEFL----SQHKAEASSRRRRKSS 350 A K G K P E +D+ + + + GE + + K A++ ++ Sbjct: 7 AGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVV 66 Query: 351 RPQAKAAPRAYSDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEI--------- 401 P K A + K+ AA+PA +T P T+P + P + Sbjct: 67 SPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKG 126 Query: 402 -PAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVEEGDEEEPAQDHQAPEAAP 457 PA + + E ++EE +D EDEE++E E E+ DE EPA +A AAP Sbjct: 127 AAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAA-MKAAAAAP 182 Score = 37.0 bits (84), Expect = 0.045 Identities = 20/78 (25%), Positives = 37/78 (47%), Gaps = 5/78 (6%) Query: 380 ETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVE 439 E + + E ++P + A A P ++ ++ + E+DE+ +D ED+ E E Sbjct: 154 EEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSE-----E 208 Query: 440 EGDEEEPAQDHQAPEAAP 457 E E PA+ +A + P Sbjct: 209 EAMETTPAKGKKAAKVVP 226 Score = 33.1 bits (74), Expect = 0.65 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 3/62 (4%) Query: 96 PPQQGGRAGMGRASRSWEGSPGEQPRGGGAGGRGR---RGRGRGSPHLSGAGDTSISDRK 152 P +GG G G + G G + GG GGRGR GRG G GD +K Sbjct: 647 PKGEGGFGGRGGGRGGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQGKK 706 Query: 153 SK 154 +K Sbjct: 707 TK 708 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 54.3 bits (129), Expect = 3e-07 Identities = 57/200 (28%), Positives = 73/200 (36%), Gaps = 56/200 (28%) Query: 369 ETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRP-------------------- 408 E +E A+P P P P P P + PP++ P P Sbjct: 828 EPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQL-VPEGTPGGGGPPALEEDLTVININSS 886 Query: 409 -----PEDEGEENEGEEDEEWEDISEDEE----------------EEEIEVEEG--DEEE 445 E+E EE E EE+EE ED E+EE EEE E EEG +EEE Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946 Query: 446 PAQDHQAPEAAPT------GIPCSEQAHGVPFSPEEPLLEPQAPGTPSSPFSPPSGHQPV 499 +D + E G E G +P P L P P S P P +P Sbjct: 947 EEEDEEEEEELEEVEDLEFGTAGGEVEEG---APPPPTLPPALPPPESPPKVQP---EPE 1000 Query: 500 SDWGEEVELNSPRTTHLAGA 519 + G +E+ P T GA Sbjct: 1001 PEPGLLLEVEEPGTEEERGA 1020 Score = 47.0 bits (110), Expect = 4e-05 Identities = 45/132 (34%), Positives = 55/132 (41%), Gaps = 11/132 (8%) Query: 362 SDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEED 421 SD ++ E +E E + E E E E E EE E EE+ Sbjct: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEE 945 Query: 422 EEWEDISEDEEEEEIEVEE-----GDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPE-E 475 EE ED E+EE EE+E E G+ EE A P P +P E V PE E Sbjct: 946 EEEEDEEEEEELEEVEDLEFGTAGGEVEEGA---PPPPTLPPALPPPESPPKVQPEPEPE 1002 Query: 476 P--LLEPQAPGT 485 P LLE + PGT Sbjct: 1003 PGLLLEVEEPGT 1014 Score = 38.1 bits (87), Expect = 0.020 Identities = 57/212 (26%), Positives = 77/212 (36%), Gaps = 24/212 (11%) Query: 306 PVPAHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHD 365 PVP E + + P P+ G S ++ P A+ P ++H Sbjct: 650 PVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHL 709 Query: 366 DRWETKEGAAS------PAPETPQPTS---PETSPKETPMQPPEIPAP---AHRPPEDEG 413 + G S P PE + S P +P TP PP IP R P Sbjct: 710 GL--SVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTP--PPTIPPDETFGGRVPRPAF 765 Query: 414 EENEGEEDEEWE-DISEDEEEEEIEVEEGDEE---EPAQDHQAPEAAPTGIPCSEQAHGV 469 + EE + E + D ++ + V EG P P APTG P + V Sbjct: 766 VHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPP--V 823 Query: 470 PFSPEEPLLEPQAPG-TPSSPFSPPSGHQPVS 500 P + EEP P APG P P PP PV+ Sbjct: 824 P-AKEEPEELPAAPGPLPPPPPPPPPVPGPVT 854 Score = 31.6 bits (70), Expect = 1.9 Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 3/38 (7%) Query: 374 AASPAPETP--QPTSPETSPKETPMQPPEIPAPAHRPP 409 AA P P QP P T P P+ PPE P+P PP Sbjct: 628 AALTHPRVPPLQPMGP-TCPTPAPVPPPEAPSPFRAPP 664 Score = 31.6 bits (70), Expect = 1.9 Identities = 50/230 (21%), Positives = 80/230 (34%), Gaps = 30/230 (13%) Query: 260 ERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQ 319 + EY ++E E+ +E + + E D E+ + + + + ++ Sbjct: 916 DEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEG 975 Query: 320 AWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAP 379 A P PP S K + P+ + P + ++ +E A AP Sbjct: 976 APPPPTLPPALPPPESPPKVQ-----------PEPEPEPGLLLEVEEPGTEEERGADTAP 1024 Query: 380 ETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEE----DEEWEDISED----- 430 +PE P + ++ A PP++ EE +EE ED S+ Sbjct: 1025 TL----APEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPP 1080 Query: 431 ----EEEEEIEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEP 476 EEE E E E +E QD A A I C P P EP Sbjct: 1081 ETPAEEEMETETEAEALQEKEQDDTAAMLADF-IDCPPDDEKPP-PPTEP 1128 >gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4 [Homo sapiens] Length = 2073 Score = 53.9 bits (128), Expect = 4e-07 Identities = 91/408 (22%), Positives = 151/408 (37%), Gaps = 95/408 (23%) Query: 149 SDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPR----RRSGP 204 S+ + +E +E + E+ E+ E+ E E + E ++ +P R L P+ +R P Sbjct: 1069 SEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPR--LTKPQSVAIKRKRP 1126 Query: 205 LEESERDRREESRRHG---------------RNWGGPDFERVR------CGLEHERQGRR 243 ++ R+ R + + D ER C +E E GR+ Sbjct: 1127 FVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRK 1186 Query: 244 AGLGSAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFK 303 L A G++R + E E+ ++ P + + +G K Sbjct: 1187 PVLRKAFQ---HQPGKKR------QTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGS-K 1236 Query: 304 DGPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSD 363 D P P Q W + K Q+K + + + P+ P Sbjct: 1237 DNPEPLK------CKQVWPKGTKRGL--SKWRQNKERKTGFKLNLYTPPETPMEPDEQVT 1288 Query: 364 HDDRWETKEGAASPAP-----------------------ETPQPTSPETSPKETP---MQ 397 +++ ET EG SP+P ET P SP TSP E P + Sbjct: 1289 VEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLI 1348 Query: 398 PPEIPAPAHRPPEDEGEENEGEEDEEWEDI--------SEDEEEEEI------------- 436 PE E+E EE EGEE+E ++ S+++EE EI Sbjct: 1349 KPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDH 1408 Query: 437 EVEEGDEEEPA--QDHQAPEAAPTGIPCSE-QAHGVPFSPEEPLLEPQ 481 E EE ++EEP+ +DH A + + + +E + +P + +LE Q Sbjct: 1409 EEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQ 1456 Score = 43.9 bits (102), Expect = 4e-04 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 6/91 (6%) Query: 368 WETKEGAASPAPETPQPTSPETSPKETPMQPPEI-PAPAHRPP-----EDEGEENEGEED 421 WE +E + + + K + PE P R ++ EE E EED Sbjct: 1018 WEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEED 1077 Query: 422 EEWEDISEDEEEEEIEVEEGDEEEPAQDHQA 452 EE E+ E+EEE+E E EE +EEE ++ Q+ Sbjct: 1078 EEEEEEEEEEEEDEEEEEEEEEEEEEENIQS 1108 Score = 42.4 bits (98), Expect = 0.001 Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 8/76 (10%) Query: 390 SPKETPMQPPEIPAPAHRPPEDEG--------EENEGEEDEEWEDISEDEEEEEIEVEEG 441 SP + + + +P RP E E +E EE+EE E+ E+EEEEE + EE Sbjct: 1035 SPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEE 1094 Query: 442 DEEEPAQDHQAPEAAP 457 +EEE ++ + +++P Sbjct: 1095 EEEEEEEEEENIQSSP 1110 Score = 33.1 bits (74), Expect = 0.65 Identities = 98/512 (19%), Positives = 160/512 (31%), Gaps = 130/512 (25%) Query: 37 EIEEDRKKAELEGVAVTAPRKGRSVEKENVAVES-EKNLGPSRRSPGTPRPPGASKGGRT 95 E+EED +K L P K R E+E KN P R + +G + Sbjct: 1179 EVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSS-NLKEGSKD 1237 Query: 96 PPQQGGRAGMGRASRSWEGSPGEQPRGGGAG-GRGRRGRGRGS---------PHLSGAGD 145 P+ + + W P+G G + R+ + R + P D Sbjct: 1238 NPEPL------KCKQVW-------PKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPD 1284 Query: 146 TSISDRKSKEWEERRRQNI-----EKMNEEMEKIAEYERNQREGVLEP-----NPVRNFL 195 ++ + KE E + E++ E E + E N+RE P +P Sbjct: 1285 EQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPE 1344 Query: 196 DDPRRRSGPLEESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLS 255 DD + EE E + EE G E E G G++ Sbjct: 1345 DDLIKPEEEEEEEEEEEEEEEEEEG---------------EEEEGG--------GNVEKD 1381 Query: 256 MTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHR 315 G + E + EK D RL H + E D E P+H H Sbjct: 1382 PDGAKSQEKEEPEISTEKEDSARLDDHEE-----EEEEDEE-----------PSHNEDHD 1425 Query: 316 YDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAA 375 DD+ + AE + S + + D + + G + Sbjct: 1426 ADDE------------DDSHMESAEVEKEELPRESFKEVLENQETFLDLN----VQPGHS 1469 Query: 376 SPAP----ETPQPTSPETSPKETPMQPPEIPAPAHRPP-----EDEGEENEGEEDEEWE- 425 +P S + PKE P +P PP + + ++N E D E++ Sbjct: 1470 NPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKE 1529 Query: 426 --------DISEDEEEEEIEVEEGDEEEPAQD-----------------HQAPEAAPTGI 460 D + + + E ++++ QD Q+P+ A T Sbjct: 1530 GNPATMEIDSETVQAVQSLTQESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLD 1589 Query: 461 PCSEQAHGVPFS-----PEEPLLEPQAPGTPS 487 C + H P S P + + +P P+ Sbjct: 1590 DCQQSDHSSPVSSVHSHPGQSVRSVNSPSVPA 1621 >gi|30795231 brain abundant, membrane attached signal protein 1 [Homo sapiens] Length = 227 Score = 53.5 bits (127), Expect = 5e-07 Identities = 42/155 (27%), Positives = 69/155 (44%), Gaps = 12/155 (7%) Query: 359 RAYSDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEG 418 + Y+ +D++ + K+ A A T E +PKE+ Q PA A E ++ EG Sbjct: 10 KGYNVNDEKAKEKDKKAEGAA-----TEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEG 64 Query: 419 EEDEEWEDISEDEEEEEIEVEEGDEEEPAQDHQAPE--AAPTGIPCSEQAHGVPFSPEEP 476 + +E+ E E++ EE + EP + A E A P P EQA P + E Sbjct: 65 KAEEK-----EGEKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEA 119 Query: 477 LLEPQAPGTPSSPFSPPSGHQPVSDWGEEVELNSP 511 +A P+ +P +G +P + GE + +P Sbjct: 120 PKAAEAAAAPAESAAPAAGEEPSKEEGEPKKTEAP 154 Score = 38.9 bits (89), Expect = 0.012 Identities = 40/191 (20%), Positives = 66/191 (34%), Gaps = 9/191 (4%) Query: 317 DDQAWARPPKPPTFGEFLSQH-KAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAA 375 + QA A P + E Q + +A + K + + AP+A + + + Sbjct: 41 EPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKAEP 100 Query: 376 SPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEE 435 APE Q + E P APA GEE EE E ++ E Sbjct: 101 PKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEEGE--------PKKTE 152 Query: 436 IEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEPQAPGTPSSPFSPPSG 495 +E + A ++ P + + P + E P P+A G +S P Sbjct: 153 APAAPAAQETKSDGAPASDSKPGSSEAAPSSKETPAATEAPSSTPKAQGPAASAEEPKPV 212 Query: 496 HQPVSDWGEEV 506 P ++ + V Sbjct: 213 EAPAANSDQTV 223 Score = 36.2 bits (82), Expect = 0.077 Identities = 32/109 (29%), Positives = 45/109 (41%), Gaps = 10/109 (9%) Query: 305 GPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDH 364 GP E + A P GE S+ + E +K+ P A AA SD Sbjct: 112 GPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEEGEP-----KKTEAPAAPAAQETKSDG 166 Query: 365 DDRWETKEGAASPAP---ETPQPT-SPETSPK-ETPMQPPEIPAPAHRP 408 ++K G++ AP ETP T +P ++PK + P E P P P Sbjct: 167 APASDSKPGSSEAAPSSKETPAATEAPSSTPKAQGPAASAEEPKPVEAP 215 >gi|221316599 chromogranin B precursor [Homo sapiens] Length = 677 Score = 53.5 bits (127), Expect = 5e-07 Identities = 68/329 (20%), Positives = 124/329 (37%), Gaps = 31/329 (9%) Query: 108 ASRSWEGSPGEQPRGGGAGGRGRRGRGRGSPHLSGAGDTSIS-----DRKSKEWEERRRQ 162 +SR G+PGE+ G + G A + S + S+E + R + Sbjct: 99 SSRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSE 158 Query: 163 NIEKMNEEMEKIAEYERNQR-------EGVLEPNPVRNFLDDPRRRSGPLEESERDRREE 215 ++ +EE E+ Y++ +R + + EP +N + R+++ +++ E R E Sbjct: 159 KSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSE 218 Query: 216 SRRHGRNWGGPDFERVRCGLEHERQGRRAG--LGSAGDMTLSMTGRERSEYLRWKQEREK 273 + G + E+ E+ + +G GS + G+ RS+ +E E+ Sbjct: 219 THAAGHSQ-----EKTH---SREKSSQESGEETGSQENHPQESKGQPRSQ-----EESEE 265 Query: 274 IDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEF 333 +++ K + R + D + G +P+ E H ++ + + GE Sbjct: 266 GEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMA-SLGEK 324 Query: 334 LSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQPTSPETSPKE 393 H + + K P + D WE G S P+P S E+ +E Sbjct: 325 RDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEE 384 Query: 394 TPMQPP--EIPAPAHRPPEDEGEENEGEE 420 P E+ AH E E EE G E Sbjct: 385 DKRNYPSLELDKMAHGYGE-ESEEERGLE 412 Score = 38.9 bits (89), Expect = 0.012 Identities = 70/312 (22%), Positives = 111/312 (35%), Gaps = 69/312 (22%) Query: 11 EEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRSVE-------- 62 E K A K+ E + R QE R+K+ E T ++ E Sbjct: 201 ERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQ 260 Query: 63 ------KENVAVESEKNLGPSRRSPGTPRPPGASKGGRTPPQQGGR------------AG 104 +E+ E +K R G RP +S+GG P ++ G A Sbjct: 261 EESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMAS 320 Query: 105 MG----------RASRSWEGSPGEQPRG-----GGAGGRGRRGRGRGSPHLSGAGDTSIS 149 +G RAS E GE+ +G R RGRGS S Sbjct: 321 LGEKRDHHSTHYRASEE-EPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQS-- 377 Query: 150 DRKSKEWEERRRQNIEKMNEEMEKIAE--YERNQREGVLEPNPVRN-----------FLD 196 + W+E ++N + E++K+A E ++ E LEP R+ F+ Sbjct: 378 ---EESWDEEDKRNYPSL--ELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMS 432 Query: 197 DPRRRSGPLEES----ERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDM 252 D R L E + ++ +++RRH + G E R L + +G GD+ Sbjct: 433 DTREEKRFLGEGHHRVQENQMDKARRHPQ---GAWKELDRNYLNYGEEGAPGKWQQQGDL 489 Query: 253 TLSMTGRERSEY 264 + RE + + Sbjct: 490 QDTKENREEARF 501 >gi|60498973 myelin transcription factor 1-like [Homo sapiens] Length = 1184 Score = 53.5 bits (127), Expect = 5e-07 Identities = 34/116 (29%), Positives = 55/116 (47%), Gaps = 7/116 (6%) Query: 342 SSRRRRKSSRPQAKA------APRAYSDHDDRWETKEGAASPAPETPQPTSPETSPKETP 395 + +R+ + +PQ A A +A S D + +G + + + P Sbjct: 58 AKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEP 117 Query: 396 MQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVEEGDEEEPAQDHQ 451 E R E+E EE + ++DE+ ED+ ++EEEEE E EE +EEE +DHQ Sbjct: 118 GDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEE-EEEEEEEEEENEDHQ 172 Score = 42.0 bits (97), Expect = 0.001 Identities = 20/51 (39%), Positives = 30/51 (58%) Query: 404 PAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVEEGDEEEPAQDHQAPE 454 P EDE + E EE+ E ED +DE+ E++E EE +EEE ++ + E Sbjct: 117 PGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEE 167 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 30/98 (30%) Query: 387 PETSPKETPMQPPEIPAPAHRP-------------------------PEDEGEENEGEED 421 P ++T + P+ PAP +P EDEGEE + D Sbjct: 56 PLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDND 115 Query: 422 EEWEDISED-----EEEEEIEVEEGDEEEPAQDHQAPE 454 E ++ ED EEEEEIE E+ D++E +D + E Sbjct: 116 EPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEE 153 >gi|78042577 MAP7 domain containing 1 [Homo sapiens] Length = 841 Score = 53.5 bits (127), Expect = 5e-07 Identities = 46/171 (26%), Positives = 69/171 (40%), Gaps = 12/171 (7%) Query: 335 SQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWE----TKEGAASPAPETPQPTSPETS 390 ++ + A +R R R A+PRA E +K +SP+ +P SP S Sbjct: 424 NEKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPS 483 Query: 391 PKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVEEGDEEEPAQD- 449 P PP+ P+P +G EE +E + E++ + + +E+E A Sbjct: 484 PGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPA 543 Query: 450 HQAPEAAPTGIPCSEQAHGVPFSPEEP-----LLEPQAPGTPSSPFSPPSG 495 AP AP+ P Q P E P L P AP P +P P +G Sbjct: 544 SPAPSPAPSPTPAPPQKEQPP--AETPTDAAVLTSPPAPAPPVTPSKPMAG 592 Score = 47.8 bits (112), Expect = 3e-05 Identities = 79/367 (21%), Positives = 122/367 (33%), Gaps = 68/367 (18%) Query: 90 SKGGRTPPQQGGRAGMGRASRSWEGSPGEQPRGGGAGGRGRRGRGRGSPHLSGAGDTSIS 149 S+ T P+ G G G PG P G AG RG H S A + Sbjct: 311 SRSAVTLPRNGRDQGRGC-------DPGRGPTWGRAGASLARGPQPDRTHPSAA--VPVC 361 Query: 150 DRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESE 209 R + ++ ER + P PVR R + P+++ E Sbjct: 362 PRSASASPLTPCSVTRSVHRCAPAGERGERRKPNAGGSPAPVRR-----RPEASPVQKKE 416 Query: 210 RDRREESRRHGRNWGGPDFERVRCGLEHERQ-GRRAGLGSAGDMTLSMTGRERSEYLRWK 268 + +E E+ + L ER +R L ++ LS + Sbjct: 417 KKDKEREN-----------EKEKSALARERSLKKRQSLPASPRARLSAS----------- 454 Query: 269 QEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPP 328 ++ + R P+ W R P P+ P H PPKPP Sbjct: 455 -TASELSPKSKARPSSPSTSWHRP-----------ASPCPSPGPGHTL-------PPKPP 495 Query: 329 TFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQPT-SP 387 + + K RR+ ++ + A P S R ++ +A+PA P P SP Sbjct: 496 SPRGTTASPKGRV--RRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSP 553 Query: 388 ETSPKETPMQPPEIPA--------PAHRPPEDEGEENEGEED-EEWEDISEDEEEEEIEV 438 +P + P E P PA PP + G D EE + ++ + E Sbjct: 554 TPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQ 613 Query: 439 EEGDEEE 445 E +E+E Sbjct: 614 REREEQE 620 Score = 43.9 bits (102), Expect = 4e-04 Identities = 94/422 (22%), Positives = 151/422 (35%), Gaps = 71/422 (16%) Query: 30 ALIRRYQEIEEDRKKAELEGVAVTAPRKGRSVEKENVAVESEKNLGPSRRSPGTPRPP-G 88 A +RR E +KK + + K R EKE A+ E++L + P +PR Sbjct: 401 APVRRRPEASPVQKKEKKD--------KERENEKEKSALARERSLKKRQSLPASPRARLS 452 Query: 89 ASKGGRTPPQQGGRAGMGRASRSWE------GSPG---------EQPRGGGAGGRG---R 130 AS P+ +A S SW SPG PRG A +G R Sbjct: 453 ASTASELSPK--SKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRR 510 Query: 131 RGRGRGSPHLSGAGDTSISDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNP 190 + + SP +G D S S R++ +E + + ++ P Sbjct: 511 KEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTD 570 Query: 191 VRNFLDDPRRRSGPLEESE-----RDRRE------ESRRHGRNWGGPDFERVRCGLEHER 239 L P + P+ S+ DR E E RR R + + R E ++ Sbjct: 571 AA-VLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDK 629 Query: 240 QGRRAGLGSAGDMTLSMTG---RERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAE 296 + R L + R + R K + E+ +QERLQ+ ++ RE +AE Sbjct: 630 RMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSRE-EAE 688 Query: 297 KTDGMFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQ-HKAEASSRRRRKSSR---- 351 + E + Q R + E + + K+E S ++++ S+ Sbjct: 689 R----------QRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANA 738 Query: 352 ----PQAKAAPRAYSDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPE--IPAPA 405 P+ A A S + ++ P P+ PQ + P KE P P PA Sbjct: 739 NGSSPEPVKAVEARSPGLQKEAVQK--EEPIPQEPQWSLPS---KELPASLVNGLQPLPA 793 Query: 406 HR 407 H+ Sbjct: 794 HQ 795 Score = 30.8 bits (68), Expect = 3.2 Identities = 20/85 (23%), Positives = 27/85 (31%), Gaps = 10/85 (11%) Query: 325 PKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQP 384 P PP + + + +S Q P E+ G P P PQ Sbjct: 35 PPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEP----------ESPSGQVGPRPAPPQE 84 Query: 385 TSPETSPKETPMQPPEIPAPAHRPP 409 SP + K PP + RPP Sbjct: 85 ESPSSEAKSRGPTPPAMGPRDARPP 109 >gi|33286446 opioid growth factor receptor [Homo sapiens] Length = 677 Score = 53.1 bits (126), Expect = 6e-07 Identities = 97/400 (24%), Positives = 133/400 (33%), Gaps = 55/400 (13%) Query: 80 SPGTPRPPGASKGGRTPPQQ---GGRAGMGRASRSWE---GSPGEQPRGGGAGGRGRRGR 133 SPG P +++G P+ GGR G RS E P E+ +G AGG G Sbjct: 315 SPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRP 374 Query: 134 GRGSPHLSGAGDTSISDRKSKEWEE--RRRQNIEKMNEEMEKIAEYERNQREGVLEPNPV 191 SP S +S R+ E + +EK+ +E A + + R G E Sbjct: 375 EPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGG- 433 Query: 192 RNFLDDPRRRSGPLEESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGD 251 DP P + R + R R E G A + S G Sbjct: 434 ----QDPGEAVQPCRQPLGARVADKVRKRRK-------------VDEGAGDSAAVASGGA 476 Query: 252 MTLSMTGRER-SEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAH 310 TL++ G S + + ++++ R G +T G GP Sbjct: 477 QTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGT---PGSPSETPGPSPAGPA-GD 532 Query: 311 EPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWET 370 EP+ + RP P AE+ S RP A D+ E+ Sbjct: 533 EPAESPSETPGPRPAGPA------GDEPAESPSET--PGPRPAGPAG-------DEPAES 577 Query: 371 KEGAASPAPETPQPTSPETSPKETPMQPPEIPA---PAHRPPEDEGEENEGEE-DEEWED 426 P+P P P SP ETP P PA PA P E G G DE E Sbjct: 578 PSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAES 637 Query: 427 ISEDEEEEEI-----EVEEGDEEEPAQDHQAPEAAPTGIP 461 SE E + E QD + +A +G P Sbjct: 638 PSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677 Score = 30.4 bits (67), Expect = 4.2 Identities = 25/83 (30%), Positives = 33/83 (39%), Gaps = 10/83 (12%) Query: 55 PRKGRSVEKENVAVESEKNLGPSRRSPGTP-RPPGASKGG-------RTPPQQGGRAGMG 106 P+ G S + V ++E GP +PG+P PG S G +P + G G Sbjct: 491 PKAGHS--ENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAG 548 Query: 107 RASRSWEGSPGEQPRGGGAGGRG 129 A SP E P AG G Sbjct: 549 PAGDEPAESPSETPGPRPAGPAG 571 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 52.8 bits (125), Expect = 8e-07 Identities = 58/305 (19%), Positives = 118/305 (38%), Gaps = 8/305 (2%) Query: 150 DRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESE 209 + + +E EE+ + EKM E+ EK+ E E + + D R +E Sbjct: 347 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 406 Query: 210 RDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRWKQ 269 R++ E R + W E++R + + Q ++ M RER + +R ++ Sbjct: 407 REKEERMREQEKMW--EQVEKMREEKKMQEQEKKT-RDQEEKMQEEERIREREKKMREEE 463 Query: 270 EREKIDQERLQRHRKPT-GQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPP 328 E + +E++Q+ + Q +EW ++ + + E +++ W + K Sbjct: 464 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPE--QKEKLWEQEKMQEQEEKIWEQEEKIR 521 Query: 329 TFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQPT--S 386 E Q K + R+ + + W+ +E E + T Sbjct: 522 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQ 581 Query: 387 PETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVEEGDEEEP 446 E +E M+ E E EE E++E+ ++ E E+E +++E +E+ Sbjct: 582 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMW 641 Query: 447 AQDHQ 451 Q+ + Sbjct: 642 EQEEK 646 Score = 50.4 bits (119), Expect = 4e-06 Identities = 59/315 (18%), Positives = 121/315 (38%), Gaps = 31/315 (9%) Query: 145 DTSISDRKSKEWE--ERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRS 202 + + +++ K WE E+ R+ EKM + E++ E E+ RE + + D R Sbjct: 347 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK-------MRDQEERM 399 Query: 203 GPLEESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERS 262 +E R++ E R + W + R ++ + + R M RER Sbjct: 400 WEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTR---DQEEKMQEEERIRERE 456 Query: 263 EYLRWKQEREKIDQERLQRHRKPTG-QWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAW 321 + +R ++E + +E++Q+ + Q +EW ++ + + E +++ W Sbjct: 457 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK--LWEQEKMQEQEEKIW 514 Query: 322 ARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPET 381 + K E Q K + R+ + + W+ +E E Sbjct: 515 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQ 574 Query: 382 PQPT--SPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVE 439 + T E +E M+ E E+ EE+E + E +E+E +++ Sbjct: 575 EKKTWDQEEKMREEERMR--------------EREKKMREEEEMMREQEEKMQEQEEKMQ 620 Query: 440 EGDEEEPAQDHQAPE 454 E +E+ Q+ + E Sbjct: 621 EQEEKMWEQEEKMQE 635 Score = 47.8 bits (112), Expect = 3e-05 Identities = 60/323 (18%), Positives = 118/323 (36%), Gaps = 26/323 (8%) Query: 150 DRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESE 209 D + +E EER R+ EKM E++EK+ E ++ Q + + ++ R R E E Sbjct: 403 DERLREKEERMREQ-EKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIR-----ERE 456 Query: 210 RDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRWKQ 269 + REE + + E++ ++ L + + E W+Q Sbjct: 457 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ 516 Query: 270 EREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPPT 329 E + DQE + K WR+E E+ D M++ + +D + Sbjct: 517 EEKIRDQEEMWGQEKK--MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQ 574 Query: 330 FGEFLSQH---KAEASSRRRRKSSRPQAKAA-----------PRAYSDHDDRWETKEGAA 375 + Q + E R R K R + + + + WE +E Sbjct: 575 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQ 634 Query: 376 SPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPE----DEGEENEGEEDEEWEDISEDE 431 + + +E + +P + E E E+ + +E++ WE ++ Sbjct: 635 EQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEK 694 Query: 432 EEEEIEVEEGDEEEPAQDHQAPE 454 + +E E + D+E+ ++ E Sbjct: 695 KTQEQEKKTWDQEKMREEESMRE 717 Score = 41.6 bits (96), Expect = 0.002 Identities = 100/465 (21%), Positives = 176/465 (37%), Gaps = 48/465 (10%) Query: 10 KEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRSVEKENVAVE 69 KEEK A + EALRR+ EA + + +K ELE + R E N+ Sbjct: 80 KEEKKASHQHQ-EALRREIEAQDHTIRILT--CQKTELETALYYSQDAARKFEDGNLGTP 136 Query: 70 SEKNLGPSRRSPGTPRPPGASKGGRTPPQQGGRAGMGRASRSWEGSPGEQPRGGGAGGRG 129 S NL S+ G+P G P + A GR SW + GE R A Sbjct: 137 SSFNLALSQAFRGSPL--GCVSTSLIPGESKDLA--GRLHHSWHFA-GELQRALSAVSTR 191 Query: 130 RRGRGRGSPHLSGAGDTSISD--RKSKEWEERRRQNIEKMNE----EMEK------IAEY 177 + R L+ D + R + EE +++N E + E EK + E Sbjct: 192 HKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKEL 251 Query: 178 ERN-QREGVLEPNPVRNFLDDPR-RRSGPLEESERDRREESRRHGRNWGGPDFERVRCGL 235 +R +R L P N L + R+ L E E+ R++ + R + + Sbjct: 252 KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMRE 311 Query: 236 EHERQGRRAGLGSAGDMTLSMTGRE-------RSEYLRWKQEREKIDQERLQRHRKPTGQ 288 + E+ R+ + L +E R + + +++ EK+ ++ + + Sbjct: 312 QEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKM 371 Query: 289 WRRE---WDAEK----TDGMFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEA 341 WR+E W+ EK + +D E R ++ R + E + + + E Sbjct: 372 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE-ERMREQEKMWEQVEKMREEK 430 Query: 342 SSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQPTSPETSPKETPM-QPPE 400 + + K +R Q + ++R +E ET + + +E M + E Sbjct: 431 KMQEQEKKTRDQEEK-----MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 485 Query: 401 IPAPAHRPPED-----EGEENEGEEDEEWEDISEDEEEEEIEVEE 440 R PE E E+ + +E++ WE + ++EE+ +E Sbjct: 486 KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE 530 Score = 40.8 bits (94), Expect = 0.003 Identities = 60/315 (19%), Positives = 113/315 (35%), Gaps = 43/315 (13%) Query: 145 DTSISDRKSKEW--EERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRS 202 + I ++ K W EER R+ KM E+ EK+ E+ RE E L R Sbjct: 285 EKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKEL----REQ 340 Query: 203 GPLEESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERS 262 L E E +E+ + + + + ER + RE+ Sbjct: 341 KELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ-----------EKQMREQE 389 Query: 263 EYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWA 322 + +R ++ER ERL+ + + + W E+ + M ++ + E R ++ Sbjct: 390 QKMRDQEERMWEQDERLREKEERMREQEKMW--EQVEKMREEKKMQEQEKKTRDQEE--- 444 Query: 323 RPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETP 382 + + + ++ R+ + + ++ WE +E E Sbjct: 445 ---------KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE------KEWQ 489 Query: 383 QPTSPETSPK---ETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEI--- 436 Q PE K + MQ E + EE G+E + W E+E+++ Sbjct: 490 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 549 Query: 437 EVEEGDEEEPAQDHQ 451 E + D+E+ D + Sbjct: 550 EEKMRDQEQKMWDQE 564 Score = 40.8 bits (94), Expect = 0.003 Identities = 35/150 (23%), Positives = 61/150 (40%), Gaps = 15/150 (10%) Query: 148 ISDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEE 207 + ++K K WE + Q EKM E+ EKI E E+ +++ + + + + R + E Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKK--TQEQEKKTWDQEKMREEESMRE 717 Query: 208 SERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRW 267 E+ REE E +R E ++ +M E W Sbjct: 718 REKKMREEE------------EMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMW 765 Query: 268 KQEREKIDQERLQRHRKPTGQWRREWDAEK 297 +Q+R +E+L H K Q + W+ E+ Sbjct: 766 EQQRLPEQKEKLWEHEKMQEQ-EKIWEQEE 794 Score = 39.7 bits (91), Expect = 0.007 Identities = 67/332 (20%), Positives = 121/332 (36%), Gaps = 34/332 (10%) Query: 150 DRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESE 209 ++K +E E++ R EKM EE E+I E E+ RE + EE E Sbjct: 429 EKKMQEQEKKTRDQEEKMQEE-ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 487 Query: 210 RDRREESRRHGRNWGGPDFERVRCGL---EHERQGRRAGLGSAGDMTLSMTGRERSEYLR 266 ++ + + W + + E + + + G M RE+ + + Sbjct: 488 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM- 546 Query: 267 WKQEREKIDQERL------QRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQA 320 W+QE + DQE+ + +K Q ++ WD E+ M ++ + E R +++ Sbjct: 547 WEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEK--MREEERMREREKKMREEEEM 604 Query: 321 WARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKA---APRAYSDHDDRWETK------ 371 + E Q + E + K + K + + + WE + Sbjct: 605 MREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQK 664 Query: 372 ----EGAASPAPETPQPTSP-----ETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDE 422 E E Q E K+T Q + E+ E E + E Sbjct: 665 EKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMRE 724 Query: 423 EWEDISEDEE---EEEIEVEEGDEEEPAQDHQ 451 E E + E EE E+E +++E +EE Q+ + Sbjct: 725 EEEMMREQEEKMQEQEEKMQEQEEEMWEQEEK 756 Score = 39.7 bits (91), Expect = 0.007 Identities = 54/315 (17%), Positives = 123/315 (39%), Gaps = 37/315 (11%) Query: 148 ISDRKSKEWE-ERRRQNIEKMNEEMEKIAEYER--NQREGVLEPNPVRNFLDDPRRRSGP 204 + ++K K WE E+ ++ EK+ E+ EKI + E Q + + +R D + Sbjct: 493 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 552 Query: 205 LEESER---DRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRER 261 + + E+ D+ E + + +++ E ER R RE Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRER-----------EKKMREE 601 Query: 262 SEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAW 321 E +R ++E+ + +E++Q Q + W+ E+ ++ E +++ W Sbjct: 602 EEMMREQEEKMQEQEEKMQE------QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 655 Query: 322 ARPPKPPTFGEFLSQHKAEASSRRRRKSSR--PQAKAAPRAYSDHDDRWETKEGAASPAP 379 + P + K + + + + + Q K + W+ ++ Sbjct: 656 EQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREE--- 712 Query: 380 ETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVE 439 E+ + + +E M+ E +++ E+ + +E+E WE + E+EE E Sbjct: 713 ESMREREKKMREEEEMMREQE------EKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWE 766 Query: 440 E---GDEEEPAQDHQ 451 + +++E +H+ Sbjct: 767 QQRLPEQKEKLWEHE 781 Score = 33.1 bits (74), Expect = 0.65 Identities = 33/140 (23%), Positives = 58/140 (41%), Gaps = 31/140 (22%) Query: 148 ISDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEE 207 + ++K K WE + Q EK+ E+ EK+ + E R EE Sbjct: 770 LPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMR---------------------GQEE 808 Query: 208 SERDRREESR-RHGRNWGGPDFERVRCGLEHERQGRRAGL-GSAGDMTLSMTG-----RE 260 R + E+ R + + WG E G E + G+ + G M M G RE Sbjct: 809 KMRGQEEKMRGQEEKMWGQ---EEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMRE 865 Query: 261 RSEYLRWKQEREKIDQERLQ 280 + E +R ++E+ + +E+++ Sbjct: 866 QEEKMRGQEEKMREQEEKMR 885 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 52.8 bits (125), Expect = 8e-07 Identities = 73/312 (23%), Positives = 121/312 (38%), Gaps = 31/312 (9%) Query: 150 DRKSKEWEERRRQNIEKMNEEME----KIAEYERNQREGVLEPNPVRNFLDDPRRRSGPL 205 D+ K EERR+Q +++ EE K E ER ++E E R ++ RR+ Sbjct: 576 DQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLK 635 Query: 206 EESERDRR-------EESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTG 258 E + +RR ++ RR R + ER+ L+ E + R A + Sbjct: 636 SEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARE 695 Query: 259 RERSEYLRWKQEREKIDQER----LQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSH 314 R +S +W+ + E R R RK GQ RR+ EK + E +H Sbjct: 696 RIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAH 755 Query: 315 RYDDQAWARPPKPPTFGEFLSQHKAEASSR--RRRKSSRPQAKAAPRAYSDHDDRWETKE 372 R + R +F Q +AE S R+R S+RP + ++R + +E Sbjct: 756 RQQQEEEQR-------RDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEER-QQRE 807 Query: 373 GAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEE 432 P E + + +E +Q E R E + EE + + ED+E Sbjct: 808 QRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQR------RERAQQLQEEEDGLQEDQE 861 Query: 433 EEEIEVEEGDEE 444 + + D++ Sbjct: 862 RRRSQEQRRDQK 873 Score = 50.1 bits (118), Expect = 5e-06 Identities = 63/335 (18%), Positives = 127/335 (37%), Gaps = 47/335 (14%) Query: 152 KSKEWEERRRQNIEKMNEEM-------EKIAEYERNQREGVLEPNPVRNFLDDPRRRSGP 204 + K +ERR Q +++ EE E+ +E+ +R+ L+ + + RR Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD------QEEERRERW 488 Query: 205 LEESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEY 264 L+ E +RRE+ R + ER L+ + + R + L ER E Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ 548 Query: 265 LRWKQEREKIDQERLQRHRKPTGQWRREW----------------DAEKTDGMFKDGPVP 308 L ++E ++++QER ++ K + RR+ E+ + K V Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVE 608 Query: 309 AHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRW 368 E R + + P+ + L + E +++ + + + + + ++R Sbjct: 609 RLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL 668 Query: 369 ETK-------EGAASPAPETPQPTSPETSPKETPMQPPEIPAPA--------HRPPEDEG 413 E + E E Q + E P ++ + A RP + EG Sbjct: 669 EQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEG 728 Query: 414 EENEGEEDEE---WEDISEDEEEEEIEVEEGDEEE 445 + E++E+ E + +EEE ++ +EE+ Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ 763 Score = 50.1 bits (118), Expect = 5e-06 Identities = 67/307 (21%), Positives = 120/307 (39%), Gaps = 40/307 (13%) Query: 151 RKSKEWEERRRQNIEKMNEEMEKIAEYERNQR-EGVLEPNPVRNFLDDPRRRSGPLEESE 209 R +E EERR Q +++ E ++ + E+ +R E L+ V + RR + + Sbjct: 566 RLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERRE----QRLK 621 Query: 210 RDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRWKQ 269 R+ EE RR ER + L E+Q RR + + R + E+ ++ Sbjct: 622 REEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERR 681 Query: 270 EREKIDQERLQ-----RHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARP 324 E+E ++E+ Q + R P QW+ E +A+ + ++RP Sbjct: 682 EQELAEEEQEQARERIKSRIPKWQWQLESEADARQS------------------KVYSRP 723 Query: 325 PKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQP 384 K + + E +RRR+ S Q + RA+ + + ++ E Sbjct: 724 RKQEG-----QRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKS- 777 Query: 385 TSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGE---EDEEWEDISEDEEEEEIEVEEG 441 E + +PP + +E ++ E E+EE E E E E++ Sbjct: 778 ---ERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFL 834 Query: 442 DEEEPAQ 448 +EEE Q Sbjct: 835 EEEEQLQ 841 Score = 49.7 bits (117), Expect = 7e-06 Identities = 98/453 (21%), Positives = 172/453 (37%), Gaps = 31/453 (6%) Query: 10 KEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRSVEKENVAVE 69 +EE++ L++R L+R++E RR QE+ E+ ++ E + P+ +E E A + Sbjct: 661 REEEEERLEQR---LKREHEEE-RREQELAEEEQEQARERIKSRIPKWQWQLESEADARQ 716 Query: 70 SEKNLGPSRRSPGTPRPPGASKGGRTPPQQGGRAGMGRASRSWEGSPGEQPRGGGAGGRG 129 S+ P R+ G R + R + RA R + EQ R + Sbjct: 717 SKVYSRP-RKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE--EQRRDFTWQWQA 773 Query: 130 RRGRGRGSPHLSGAGDTSISDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPN 189 RG LS + EER+++ + EE EK E R QR E Sbjct: 774 EEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEK--EQRRRQRR---ERE 828 Query: 190 PVRNFLDDP-----RRRSGPLEESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRA 244 FL++ R R+ L+E E +E+ R D ++ R LE ER+ RR Sbjct: 829 KELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRD-QKWRWQLEEERKRRRH 887 Query: 245 GLGSAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMF-- 302 L + + + R+ + L+ ++E + ++ +R ++ Q+R E ++ + Sbjct: 888 TLYAKPALQEQL--RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLR 945 Query: 303 -KDGPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAY 361 + E +Y + + GE + + + ++ R+ Q + Sbjct: 946 EEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR 1005 Query: 362 SDHDDR----WETKEGAASPAPETPQPTSPETSPK----ETPMQPPEIPAPAHRPPEDEG 413 + + R WE + + + E K E Q E + G Sbjct: 1006 EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLG 1065 Query: 414 EENEGEEDEEWEDISEDEEEEEIEVEEGDEEEP 446 EE E +E E EEE + E E+ EEP Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEP 1098 Score = 47.4 bits (111), Expect = 3e-05 Identities = 71/310 (22%), Positives = 116/310 (37%), Gaps = 24/310 (7%) Query: 154 KEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESERDRR 213 +E + RR Q + + EE ++E+ +RE L+ + RR E E +R Sbjct: 415 REQQLRREQQLRREQEEERHEQKHEQERREQRLKR-------EQEERRDWLKREEETERH 467 Query: 214 EESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRWKQEREK 273 E+ RR + + ER L+ E + RR + L ER E +QE E Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQ-ERREQQLRREQEERREQRLKRQEEE- 525 Query: 274 IDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEF 333 ERLQ+ + Q RRE + E+ + + K E R + + + Sbjct: 526 ---ERLQQRLRSEQQLRREQE-ERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR 581 Query: 334 LSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQPTSPETSPKE 393 + + + R + + + K + ++R E + P E Q +E Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641 Query: 394 TPMQPPEIPAPAHRPPEDEGEEN--EGEEDEEWEDISEDEEEEEIEVEEGDEEEPAQDHQ 451 Q R ++ E+ EE+E E + E EEE +E EEE Q Sbjct: 642 RRQQQ------LRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE---QEQ 692 Query: 452 APEAAPTGIP 461 A E + IP Sbjct: 693 ARERIKSRIP 702 Score = 47.4 bits (111), Expect = 3e-05 Identities = 109/535 (20%), Positives = 203/535 (37%), Gaps = 97/535 (18%) Query: 5 LDLKSKEEKDAELDK----RIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRS 60 L+ + +EE++ + ++ R E +R+ + L R+Y+E EE +++ E + ++ R Sbjct: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQ---LLREEQEKRR 1192 Query: 61 VEKENVAVESEKNLGPSRRSPGTPRPPGASKGGRTPPQQGGRAGMGRASRSWEGSPGEQP 120 E+E E E+ R+ + + P++ + +G EQ Sbjct: 1193 QERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVY--CKGRENEQF 1250 Query: 121 RGGGAGGRGRRGRGRGSPHLSGAGDTSISDRKSKEWEERRRQNIEKMNEEMEKIAEYERN 180 R R + HL G +++ + W++R R E+ E E+ E +R Sbjct: 1251 RQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRR 1310 Query: 181 QREGVLEPNPVRNFLDDPRRR------------------SGPLEESERDR--REESRRH- 219 R+ E +R ++ RRR PL ERDR REE RH Sbjct: 1311 DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQ 1370 Query: 220 --GRNWGGPD-----FERVRCGLEHERQGR-----------RAGLGSAGDMTLSMTGRER 261 GR + + ER R L+ E+Q R R + LS R+R Sbjct: 1371 EQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR 1430 Query: 262 ------SEYLRWKQEREKIDQE---RLQRHRKPTGQ------------WRREWD------ 294 + R ++ER+ +++E R +RHRK + R+E D Sbjct: 1431 KFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEE 1490 Query: 295 -----AEKTDGMFKDGPVPAHEPSHRY--DDQAWARPPKPPTFGEFLSQHKAEASSRRRR 347 ++ D F++ + + EP ++ ++Q R + F + E RR+ Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQ-------EEQQLRRQ 1543 Query: 348 KSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHR 407 + + + + R + + + + +E E + E Q + + Sbjct: 1544 ERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQ 1603 Query: 408 PPEDEGEENEGEEDE----EWEDISEDEEEEEIEVEEGD----EEEPAQDHQAPE 454 EG++ +E + E E + ++ EE+++ +E D EEEP Q E Sbjct: 1604 LRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQERE 1658 Score = 47.0 bits (110), Expect = 4e-05 Identities = 100/485 (20%), Positives = 177/485 (36%), Gaps = 63/485 (12%) Query: 7 LKSKEEKDAELDKRIEALRRKNE----ALIRRYQEIEEDRKKAELEGVAVTAPRKGRSVE 62 LK +EEK E ++R + L+R+ E L++R +E + R K E E ++ + E Sbjct: 550 LKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE---ERLEQRLKREE 606 Query: 63 KENVAVESEKNLGPSRRSPGTPRPPGASKGGRTPPQQGGRAGMGRASRSWEGSPGEQPRG 122 E + E + R P R K ++ + + R + E+ Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE-- 664 Query: 123 GGAGGRGRRGRGRGSPHLSGAGDTSISDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQ- 181 R + H + +++ + ++ ER + I K ++E A+ +++ Sbjct: 665 -----EERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKV 719 Query: 182 --REGVLEPNPVRNFLDDPRRRS------GPLEESERDRREESRRHGRNWGGPDFERVRC 233 R E R ++ RRR E + R ++EE +R W E+ Sbjct: 720 YSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSER 779 Query: 234 GLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREW 293 G +R R L + L R++ E +E EK + R +R R+ Q+ E Sbjct: 780 G--RQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE 837 Query: 294 D-----------AEKTDGMFKDGPVPAHEPSHRYDDQAW----------------ARPPK 326 + E+ DG+ +D + R DQ W A+P Sbjct: 838 EQLQRRERAQQLQEEEDGLQEDQERRRSQEQRR--DQKWRWQLEEERKRRRHTLYAKPAL 895 Query: 327 PPTF--GEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQP 384 + L Q + E R R+ R Q + R Y + + + +E E + Sbjct: 896 QEQLRKEQQLLQEEEEELQREEREKRRRQEQ--ERQYREEEQLQQEEEQLLREEREKRRR 953 Query: 385 TSPETS-PKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEE---EEIEVEE 440 E K+ +Q E P + +E E + EE E++ ++EE+ EE E Sbjct: 954 QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE-EELQQEEEQLLREEREKRR 1012 Query: 441 GDEEE 445 E E Sbjct: 1013 RQEWE 1017 Score = 46.2 bits (108), Expect = 7e-05 Identities = 59/297 (19%), Positives = 115/297 (38%), Gaps = 22/297 (7%) Query: 151 RKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESER 210 R+ ++ EE+++Q + + + K E R Q+E E R RR L + Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE--QQEERREQQLRREQE 344 Query: 211 DRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRWKQE 270 +RRE+ R + + ER L E++ R + L R + LR +Q+ Sbjct: 345 ERREQQLRREQ-----EEERREQQLRREQEEERREQQLRREQQL-----RREQQLRREQQ 394 Query: 271 REKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPPTF 330 + Q R ++ + Q RRE + + ++ HE H + + + Sbjct: 395 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEER 454 Query: 331 GEFLS-QHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRW---ETKEGAASPAPETPQPTS 386 ++L + + E + RRK + + R +RW E +E Q Sbjct: 455 RDWLKREEETERHEQERRKQQLKRDQEEERR-----ERWLKLEEEERREQQERREQQLRR 509 Query: 387 PETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVEEGDE 443 + +E ++ E + E ++ E++E E + + EEE+ +E E ++ Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSE-QQLRREQEERREQLLKREEEKRLEQERREQ 565 Score = 45.1 bits (105), Expect = 2e-04 Identities = 61/300 (20%), Positives = 108/300 (36%), Gaps = 25/300 (8%) Query: 152 KSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESE-- 209 + K EE+++Q E+ + ++ E E +RE VL + ++P+R+ EE E Sbjct: 219 RRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQL 278 Query: 210 ---------RDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRE 260 R+R+EE ++ R R + E ER+ ++ + R Sbjct: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQ---EEERREQQEERREQQERREQQEERR 335 Query: 261 RSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQA 320 + R ++ER + R Q + Q RRE + E+ + + E R + Q Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQL 395 Query: 321 WARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPE 380 Q + E RR ++ R Q + H+ + E + E Sbjct: 396 RREQQLRRE-----QQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE 450 Query: 381 TPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVEE 440 + +ET E R + + E E E W + E+E E+ E E Sbjct: 451 QEERRDWLKREEETERHEQE------RRKQQLKRDQEEERRERWLKLEEEERREQQERRE 504 Score = 39.3 bits (90), Expect = 0.009 Identities = 72/315 (22%), Positives = 122/315 (38%), Gaps = 43/315 (13%) Query: 150 DRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDP---RRRSGPLE 206 DRK +E E+ R++ E+ E+ ++ R + + V R F++D RR+ G + Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQERDRKF-RLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612 Query: 207 -ESERDR-----------REESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTL 254 ERDR REE + H + ER R LE E Q RR Sbjct: 1613 LRQERDRKFREDEQLLQEREEQQLHRQ-------ERDRKFLEEEPQLRRQEREQQLRHDR 1665 Query: 255 SMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSH 314 RE + L+ +E++ QER ++ R+ Q RR+ K + ++ + E Sbjct: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKF--LQEEQQLRRQELER 1723 Query: 315 RYDDQAWARPPKPPTFGEFLSQHKAEASSRRRR----KSSRPQAKAAPRAYSDHDDRWET 370 ++ ++ R + Q + R R+ + RP+ + + D ++ Sbjct: 1724 KFREEEQLR--------QETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFRE 1775 Query: 371 KEGAASPAPETPQPTSPETSPK--ETPMQPPEIPAPAHRPPEDEGE---ENEGEEDEEWE 425 +E E Q S E+ K E E RP + +G+ E E + EE E Sbjct: 1776 EEQLRQER-EEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834 Query: 426 DISEDEEEEEIEVEE 440 E + + EE Sbjct: 1835 QRLRQERDRQYRAEE 1849 Score = 31.2 bits (69), Expect = 2.5 Identities = 32/138 (23%), Positives = 57/138 (41%), Gaps = 15/138 (10%) Query: 151 RKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESER 210 R +E ++ RRQ ++ E E++ + Q+ E + R F ++ + R E E+ Sbjct: 1756 RPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESD--RKFREEEQLRQ---EREEQ 1810 Query: 211 DRREESRRHGRNWGGPDFE----RVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLR 266 R + R W + R E +RQ R A + + R E Sbjct: 1811 QLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR------AEEQFATQEKSRREEQEL 1864 Query: 267 WKQEREKIDQERLQRHRK 284 W++E +K QER ++ R+ Sbjct: 1865 WQEEEQKRRQERERKLRE 1882 >gi|62244004 modulator of estrogen induced transcription isoform b [Homo sapiens] Length = 1016 Score = 52.8 bits (125), Expect = 8e-07 Identities = 72/319 (22%), Positives = 120/319 (37%), Gaps = 77/319 (24%) Query: 147 SISDRKSKEWEERRRQNIEKMNEEM--EKIAEYERNQREGVLEPNPVRNFLDDPRRRSGP 204 S+ ++ K++ + EKM E+ E + +ER +R ++ RRR Sbjct: 572 SLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFER-----------LRRAMELRRRR--- 617 Query: 205 LEESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEY 264 E +ER+RRE ER+R E E + R RER E Sbjct: 618 -EIAERERRER-------------ERIRIIREREERERL------------QRERERLEI 651 Query: 265 LRWKQEREKIDQERLQRHRKPTGQWRRE--------------------WDAEKTDGMFKD 304 R K ERE++++ERL+R R Q RR+ ++ EK + + + Sbjct: 652 ERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRP 711 Query: 305 GPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRR--------RRKSSRPQAKA 356 V HR DD W+ K + H ++ S ++ R + P++ A Sbjct: 712 RDV-----DHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSA 766 Query: 357 APRAYSDHDDRW--ETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGE 414 + + DR+ +++ A P P+ + + E P P + E + Sbjct: 767 VQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRR 826 Query: 415 ENEGEEDEEWEDISEDEEE 433 E GE DE I D + Sbjct: 827 EVRGERDERRTVIIHDRPD 845 Score = 31.2 bits (69), Expect = 2.5 Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 2/56 (3%) Query: 405 AHRPPEDEGEENEGEEDEEWEDISEDEEEEE--IEVEEGDEEEPAQDHQAPEAAPT 458 AH E EG E+ +ED E ++I E E++ + ++G+EEE ++ EA T Sbjct: 151 AHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKEGSLAEADHT 206 Score = 30.0 bits (66), Expect = 5.5 Identities = 24/68 (35%), Positives = 37/68 (54%), Gaps = 6/68 (8%) Query: 8 KSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRSV---EKE 64 K KE++ E R E LRR E +RR +EI E R++ E E + + R+ R E+E Sbjct: 591 KMKEQRLREHLVRFERLRRAME--LRRRREIAE-RERRERERIRIIREREERERLQRERE 647 Query: 65 NVAVESEK 72 + +E +K Sbjct: 648 RLEIERQK 655 >gi|63176611 modulator of estrogen induced transcription isoform a [Homo sapiens] Length = 1034 Score = 52.8 bits (125), Expect = 8e-07 Identities = 72/319 (22%), Positives = 120/319 (37%), Gaps = 77/319 (24%) Query: 147 SISDRKSKEWEERRRQNIEKMNEEM--EKIAEYERNQREGVLEPNPVRNFLDDPRRRSGP 204 S+ ++ K++ + EKM E+ E + +ER +R ++ RRR Sbjct: 590 SLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFER-----------LRRAMELRRRR--- 635 Query: 205 LEESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEY 264 E +ER+RRE ER+R E E + R RER E Sbjct: 636 -EIAERERRER-------------ERIRIIREREERERL------------QRERERLEI 669 Query: 265 LRWKQEREKIDQERLQRHRKPTGQWRRE--------------------WDAEKTDGMFKD 304 R K ERE++++ERL+R R Q RR+ ++ EK + + + Sbjct: 670 ERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRP 729 Query: 305 GPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRR--------RRKSSRPQAKA 356 V HR DD W+ K + H ++ S ++ R + P++ A Sbjct: 730 RDV-----DHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSA 784 Query: 357 APRAYSDHDDRW--ETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGE 414 + + DR+ +++ A P P+ + + E P P + E + Sbjct: 785 VQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRR 844 Query: 415 ENEGEEDEEWEDISEDEEE 433 E GE DE I D + Sbjct: 845 EVRGERDERRTVIIHDRPD 863 Score = 30.4 bits (67), Expect = 4.2 Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 2/47 (4%) Query: 405 AHRPPEDEGEENEGEEDEEWEDISEDEEEEE--IEVEEGDEEEPAQD 449 AH E EG E+ +ED E ++I E E++ + ++G+EEE +D Sbjct: 151 AHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKD 197 Score = 30.0 bits (66), Expect = 5.5 Identities = 24/68 (35%), Positives = 37/68 (54%), Gaps = 6/68 (8%) Query: 8 KSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRSV---EKE 64 K KE++ E R E LRR E +RR +EI E R++ E E + + R+ R E+E Sbjct: 609 KMKEQRLREHLVRFERLRRAME--LRRRREIAE-RERRERERIRIIREREERERLQRERE 665 Query: 65 NVAVESEK 72 + +E +K Sbjct: 666 RLEIERQK 673 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.129 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,745,961 Number of Sequences: 37866 Number of extensions: 2058318 Number of successful extensions: 36969 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 751 Number of HSP's successfully gapped in prelim test: 1867 Number of HSP's that attempted gapping in prelim test: 15256 Number of HSP's gapped (non-prelim): 13202 length of query: 531 length of database: 18,247,518 effective HSP length: 107 effective length of query: 424 effective length of database: 14,195,856 effective search space: 6019042944 effective search space used: 6019042944 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (22.0 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.