Guide to the Human Genome
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Search of human proteins with 7657671

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7657671 upstream binding transcription factor, RNA
polymerase I isoform a [Homo sapiens]
         (764 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7657671 upstream binding transcription factor, RNA polymerase...  1548   0.0  
gi|115529449 upstream binding transcription factor, RNA polymera...  1454   0.0  
gi|115529451 upstream binding transcription factor, RNA polymera...  1454   0.0  
gi|239741668 PREDICTED: upstream binding transcription factor, R...   255   1e-67
gi|169163306 PREDICTED: upstream binding transcription factor, R...   255   1e-67
gi|221136785 upstream binding transcription factor, RNA polymera...   251   2e-66
gi|239753269 PREDICTED: upstream binding transcription factor, R...   244   2e-64
gi|239741686 PREDICTED: upstream binding transcription factor, R...   244   2e-64
gi|239747816 PREDICTED: upstream binding transcription factor, R...   244   3e-64
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    89   1e-17
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    84   6e-16
gi|4504425 high-mobility group box 1 [Homo sapiens]                    81   3e-15
gi|194688135 high-mobility group box 2 [Homo sapiens]                  79   2e-14
gi|194688133 high-mobility group box 2 [Homo sapiens]                  79   2e-14
gi|11321591 high-mobility group box 2 [Homo sapiens]                   79   2e-14
gi|221219020 NYD-SP11 protein [Homo sapiens]                           78   3e-14
gi|55956788 nucleolin [Homo sapiens]                                   78   4e-14
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    77   5e-14
gi|239744307 PREDICTED: similar to hCG1991922 [Homo sapiens]           76   1e-13
gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]             76   1e-13
gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens]           76   1e-13
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    75   2e-13
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    75   2e-13
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          75   2e-13
gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens]           75   3e-13
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    74   4e-13
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    74   4e-13
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    74   5e-13
gi|21735415 centromere protein B [Homo sapiens]                        72   1e-12
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     72   3e-12

>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 1548 bits (4007), Expect = 0.0
 Identities = 764/764 (100%), Positives = 764/764 (100%)

Query: 1   MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF 60
           MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF
Sbjct: 1   MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF 60

Query: 61  KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF 120
           KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF
Sbjct: 61  KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF 120

Query: 121 RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR 180
           RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR
Sbjct: 121 RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR 180

Query: 181 EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDK 240
           EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDK
Sbjct: 181 EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDK 240

Query: 241 KRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKP 300
           KRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKP
Sbjct: 241 KRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKP 300

Query: 301 PPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLR 360
           PPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLR
Sbjct: 301 PPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLR 360

Query: 361 FLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEE 420
           FLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEE
Sbjct: 361 FLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEE 420

Query: 421 KRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGK 480
           KRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGK
Sbjct: 421 KRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGK 480

Query: 481 LPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKR 540
           LPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKR
Sbjct: 481 LPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKR 540

Query: 541 YERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEI 600
           YERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEI
Sbjct: 541 YERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEI 600

Query: 601 GSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLR 660
           GSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLR
Sbjct: 601 GSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLR 660

Query: 661 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED 720
           GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED
Sbjct: 661 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED 720

Query: 721 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
           GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN
Sbjct: 721 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 1454 bits (3765), Expect = 0.0
 Identities = 727/764 (95%), Positives = 727/764 (95%), Gaps = 37/764 (4%)

Query: 1   MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF 60
           MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF
Sbjct: 1   MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF 60

Query: 61  KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF 120
           KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF
Sbjct: 61  KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF 120

Query: 121 RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR 180
           RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR
Sbjct: 121 RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR 180

Query: 181 EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDK 240
           EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPD                    
Sbjct: 181 EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPD-------------------- 220

Query: 241 KRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKP 300
                            EIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKP
Sbjct: 221 -----------------EIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKP 263

Query: 301 PPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLR 360
           PPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLR
Sbjct: 264 PPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLR 323

Query: 361 FLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEE 420
           FLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEE
Sbjct: 324 FLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEE 383

Query: 421 KRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGK 480
           KRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGK
Sbjct: 384 KRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGK 443

Query: 481 LPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKR 540
           LPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKR
Sbjct: 444 LPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKR 503

Query: 541 YERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEI 600
           YERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEI
Sbjct: 504 YERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEI 563

Query: 601 GSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLR 660
           GSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLR
Sbjct: 564 GSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLR 623

Query: 661 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED 720
           GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED
Sbjct: 624 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED 683

Query: 721 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
           GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN
Sbjct: 684 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 1454 bits (3765), Expect = 0.0
 Identities = 727/764 (95%), Positives = 727/764 (95%), Gaps = 37/764 (4%)

Query: 1   MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF 60
           MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF
Sbjct: 1   MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF 60

Query: 61  KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF 120
           KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF
Sbjct: 61  KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF 120

Query: 121 RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR 180
           RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR
Sbjct: 121 RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR 180

Query: 181 EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDK 240
           EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPD                    
Sbjct: 181 EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPD-------------------- 220

Query: 241 KRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKP 300
                            EIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKP
Sbjct: 221 -----------------EIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKP 263

Query: 301 PPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLR 360
           PPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLR
Sbjct: 264 PPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLR 323

Query: 361 FLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEE 420
           FLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEE
Sbjct: 324 FLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEE 383

Query: 421 KRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGK 480
           KRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGK
Sbjct: 384 KRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGK 443

Query: 481 LPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKR 540
           LPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKR
Sbjct: 444 LPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKR 503

Query: 541 YERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEI 600
           YERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEI
Sbjct: 504 YERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEI 563

Query: 601 GSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLR 660
           GSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLR
Sbjct: 564 GSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLR 623

Query: 661 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED 720
           GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED
Sbjct: 624 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED 683

Query: 721 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
           GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN
Sbjct: 684 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727


>gi|239741668 PREDICTED: upstream binding transcription factor, RNA
           polymerase I-like 3 [Homo sapiens]
          Length = 457

 Score =  255 bits (651), Expect = 1e-67
 Identities = 143/317 (45%), Positives = 201/317 (63%), Gaps = 11/317 (3%)

Query: 10  DLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCK 69
           D++MA P+ Q  WS  D+L LLECM+NNLPS+D+  F +T+SHMDW KVAFK+FSG+MC+
Sbjct: 62  DIKMALPRSQGHWSNADILRLLECMENNLPSDDNGTFSSTQSHMDWGKVAFKNFSGEMCR 121

Query: 70  LKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAK 129
           LKW+EIS  +RKF TL +L+L+A++ VKN  K +K + HPDFPK+PLT Y RFF E   +
Sbjct: 122 LKWLEISCSLRKFSTLKKLVLEAKKCVKNTNKSQKGRNHPDFPKRPLTAYIRFFKENWPQ 181

Query: 130 YAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQN 189
           Y++++P M + +LTKILSKKYKELPE+ K KYIQDFQ+EKQEFE  L RFRE+HPDL Q 
Sbjct: 182 YSQMYPGMRSQELTKILSKKYKELPEQMKQKYIQDFQKEKQEFEEKLVRFREEHPDLDQK 241

Query: 190 AKKSDIPEKPKTP-QQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRL---KW 245
            KKSDI ++ +T  Q+    + ++V    + D   K+VK     Q   ++   +     W
Sbjct: 242 GKKSDISKRIQTKVQKKVQKNIEEVTSLPKTDQFFKKVKFHGEPQKPPMNGYHKFHQDSW 301

Query: 246 IHKALEQ---RKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPP 302
             K L+    R+   EI R + Q+ P+   S++   KS     +++ K + D       P
Sbjct: 302 SSKELQHLSLRERMVEIGRRW-QRIPQ---SQKDHYKSQAELLQKEYKVELDLWLKTLSP 357

Query: 303 NSYSLYCAELMANMKDV 319
             Y+ Y     A  K++
Sbjct: 358 EDYAAYKESTYAKGKNM 374



 Score =  181 bits (459), Expect = 2e-45
 Identities = 123/363 (33%), Positives = 180/363 (49%), Gaps = 57/363 (15%)

Query: 378 KMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESEL 437
           K L +  K+     +K    + G+   + PKRP++A   F +E   Q  +  P +   EL
Sbjct: 138 KKLVLEAKKCVKNTNKS---QKGRNHPDFPKRPLTAYIRFFKENWPQYSQMYPGMRSQEL 194

Query: 438 TRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVI 497
           T++L++ + +L E+ K KY         Q  +K   E EE+                   
Sbjct: 195 TKILSKKYKELPEQMKQKY--------IQDFQKEKQEFEEK------------------- 227

Query: 498 GDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAED--QKRYERELSEMRAPPAAT 555
              L RF+ +             ++++K K   I K  +   QK+ ++ + E+ + P   
Sbjct: 228 ---LVRFREEHP-----------DLDQKGKKSDISKRIQTKVQKKVQKNIEEVTSLPKTD 273

Query: 556 NSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHY 615
              KK+KF GEP+KPPMNGY KF Q+  S+ EL HL L+ERMVEIG RWQRI QSQK+HY
Sbjct: 274 QFFKKVKFHGEPQKPPMNGYHKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQSQKDHY 333

Query: 616 KKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKS 675
           K  AE  QK+YKV LDLW+K+LSP+D AAYKE    K K+M  + GP P   +T  QS S
Sbjct: 334 KSQAELLQKEYKVELDLWLKTLSPEDYAAYKESTYAKGKNMAMMGGPAPSLKQTDPQSSS 393

Query: 676 ES--EEDDEEDEDDEDEDEEEEDD---------ENGDSSEDGGDSSESSSEDESEDGDEN 724
               +E   E +  +    E             E  ++ +  G+  ESS+  +   G++ 
Sbjct: 394 AKGLQEGFGEGQGLQAAGTEASQTIWVNCQVSMEPEENRKKDGEEEESSNSLDCSSGEDM 453

Query: 725 EED 727
           E D
Sbjct: 454 EVD 456



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 62/256 (24%), Positives = 121/256 (47%), Gaps = 40/256 (15%)

Query: 187 IQNAKKS-------DIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSD 239
           ++N  KS       D P++P T    ++      Y ++ P   ++E+   L K++ +L +
Sbjct: 148 VKNTNKSQKGRNHPDFPKRPLTAYIRFFKENWPQYSQMYPGMRSQELTKILSKKYKELPE 207

Query: 240 KKRLKWIHKALEQRKEYEEIMRDYIQKHPELNIS--EEGITKSTLTKAERQL-------- 289
           + + K+I    ++++E+EE +  + ++HP+L+    +  I+K   TK ++++        
Sbjct: 208 QMKQKYIQDFQKEKQEFEEKLVRFREEHPDLDQKGKKSDISKRIQTKVQKKVQKNIEEVT 267

Query: 290 ----------KDKFDGRPTKPPPNSYSLYCAELMAN--MKDVPSTERMVLCSQQWKLLSQ 337
                     K KF G P KPP N Y  +  +  ++  ++ +   ERMV   ++W+ + Q
Sbjct: 268 SLPKTDQFFKKVKFHGEPQKPPMNGYHKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQ 327

Query: 338 KEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQ 397
            +KD Y  + +  +K+Y+VEL  +L++L  E+               K++T    K  A 
Sbjct: 328 SQKDHYKSQAELLQKEYKVELDLWLKTLSPEDYAAY-----------KESTYAKGKNMAM 376

Query: 398 EGGKGGSEKPKRPVSA 413
            GG   S K   P S+
Sbjct: 377 MGGPAPSLKQTDPQSS 392


>gi|169163306 PREDICTED: upstream binding transcription factor, RNA
           polymerase I-like 5 [Homo sapiens]
          Length = 471

 Score =  255 bits (651), Expect = 1e-67
 Identities = 143/317 (45%), Positives = 201/317 (63%), Gaps = 11/317 (3%)

Query: 10  DLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCK 69
           D++MA P+ Q  WS  D+L LLECM+NNLPS+D+  F +T+SHMDW KVAFK+FSG+MC+
Sbjct: 76  DIKMALPRSQGHWSNADILRLLECMENNLPSDDNGTFSSTQSHMDWGKVAFKNFSGEMCR 135

Query: 70  LKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAK 129
           LKW+EIS  +RKF TL +L+L+A++ VKN  K +K + HPDFPK+PLT Y RFF E   +
Sbjct: 136 LKWLEISCSLRKFSTLKKLVLEAKKCVKNTNKSQKGRNHPDFPKRPLTAYIRFFKENWPQ 195

Query: 130 YAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQN 189
           Y++++P M + +LTKILSKKYKELPE+ K KYIQDFQ+EKQEFE  L RFRE+HPDL Q 
Sbjct: 196 YSQMYPGMRSQELTKILSKKYKELPEQMKQKYIQDFQKEKQEFEEKLVRFREEHPDLDQK 255

Query: 190 AKKSDIPEKPKTP-QQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRL---KW 245
            KKSDI ++ +T  Q+    + ++V    + D   K+VK     Q   ++   +     W
Sbjct: 256 GKKSDISKRIQTKVQKKVQKNIEEVTSLPKTDQFFKKVKFHGEPQKPPMNGYHKFHQDSW 315

Query: 246 IHKALEQ---RKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPP 302
             K L+    R+   EI R + Q+ P+   S++   KS     +++ K + D       P
Sbjct: 316 SSKELQHLSLRERMVEIGRRW-QRIPQ---SQKDHYKSQAELLQKEYKVELDLWLKTLSP 371

Query: 303 NSYSLYCAELMANMKDV 319
             Y+ Y     A  K++
Sbjct: 372 EDYAAYKESTYAKGKNM 388



 Score =  181 bits (459), Expect = 2e-45
 Identities = 123/363 (33%), Positives = 180/363 (49%), Gaps = 57/363 (15%)

Query: 378 KMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESEL 437
           K L +  K+     +K    + G+   + PKRP++A   F +E   Q  +  P +   EL
Sbjct: 152 KKLVLEAKKCVKNTNKS---QKGRNHPDFPKRPLTAYIRFFKENWPQYSQMYPGMRSQEL 208

Query: 438 TRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVI 497
           T++L++ + +L E+ K KY         Q  +K   E EE+                   
Sbjct: 209 TKILSKKYKELPEQMKQKY--------IQDFQKEKQEFEEK------------------- 241

Query: 498 GDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAED--QKRYERELSEMRAPPAAT 555
              L RF+ +             ++++K K   I K  +   QK+ ++ + E+ + P   
Sbjct: 242 ---LVRFREEHP-----------DLDQKGKKSDISKRIQTKVQKKVQKNIEEVTSLPKTD 287

Query: 556 NSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHY 615
              KK+KF GEP+KPPMNGY KF Q+  S+ EL HL L+ERMVEIG RWQRI QSQK+HY
Sbjct: 288 QFFKKVKFHGEPQKPPMNGYHKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQSQKDHY 347

Query: 616 KKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKS 675
           K  AE  QK+YKV LDLW+K+LSP+D AAYKE    K K+M  + GP P   +T  QS S
Sbjct: 348 KSQAELLQKEYKVELDLWLKTLSPEDYAAYKESTYAKGKNMAMMGGPAPSLKQTDPQSSS 407

Query: 676 ES--EEDDEEDEDDEDEDEEEEDD---------ENGDSSEDGGDSSESSSEDESEDGDEN 724
               +E   E +  +    E             E  ++ +  G+  ESS+  +   G++ 
Sbjct: 408 AKGLQEGFGEGQGLQAAGTEASQTIWVNCQVSMEPEENRKKDGEEEESSNSLDCSSGEDM 467

Query: 725 EED 727
           E D
Sbjct: 468 EVD 470



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 62/256 (24%), Positives = 121/256 (47%), Gaps = 40/256 (15%)

Query: 187 IQNAKKS-------DIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSD 239
           ++N  KS       D P++P T    ++      Y ++ P   ++E+   L K++ +L +
Sbjct: 162 VKNTNKSQKGRNHPDFPKRPLTAYIRFFKENWPQYSQMYPGMRSQELTKILSKKYKELPE 221

Query: 240 KKRLKWIHKALEQRKEYEEIMRDYIQKHPELNIS--EEGITKSTLTKAERQL-------- 289
           + + K+I    ++++E+EE +  + ++HP+L+    +  I+K   TK ++++        
Sbjct: 222 QMKQKYIQDFQKEKQEFEEKLVRFREEHPDLDQKGKKSDISKRIQTKVQKKVQKNIEEVT 281

Query: 290 ----------KDKFDGRPTKPPPNSYSLYCAELMAN--MKDVPSTERMVLCSQQWKLLSQ 337
                     K KF G P KPP N Y  +  +  ++  ++ +   ERMV   ++W+ + Q
Sbjct: 282 SLPKTDQFFKKVKFHGEPQKPPMNGYHKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQ 341

Query: 338 KEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQ 397
            +KD Y  + +  +K+Y+VEL  +L++L  E+               K++T    K  A 
Sbjct: 342 SQKDHYKSQAELLQKEYKVELDLWLKTLSPEDYAAY-----------KESTYAKGKNMAM 390

Query: 398 EGGKGGSEKPKRPVSA 413
            GG   S K   P S+
Sbjct: 391 MGGPAPSLKQTDPQSS 406


>gi|221136785 upstream binding transcription factor, RNA polymerase
           I-like 1 [Homo sapiens]
          Length = 393

 Score =  251 bits (641), Expect = 2e-66
 Identities = 140/317 (44%), Positives = 202/317 (63%), Gaps = 11/317 (3%)

Query: 13  MAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCKLKW 72
           MA P+ Q  WS +D+L LLECM+NN PS+D+S F +T+SHMDW KVAFK+FSG+MC+LKW
Sbjct: 1   MALPRSQGHWSNKDILRLLECMENNRPSDDNSTFSSTQSHMDWGKVAFKNFSGEMCRLKW 60

Query: 73  VEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAK 132
           +EIS  +RKF TL EL+L+A++ VK   K +K +  PDFPK+PLT Y RFF E   +Y++
Sbjct: 61  LEISCNLRKFGTLKELVLEAKKCVKKMNKSQKYRNGPDFPKRPLTAYNRFFKESWPQYSQ 120

Query: 133 LHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKK 192
           ++P M + +LTKILSKKY+ELPE+ K KYIQDF++EKQEFE  LARFRE+HPDL+Q AKK
Sbjct: 121 MYPGMRSQELTKILSKKYRELPEQMKQKYIQDFRKEKQEFEEKLARFREEHPDLVQKAKK 180

Query: 193 SDIPEKPKTP-QQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRL---KWIHK 248
           S + ++ +   Q+ +  + ++V    + D   K+VK     Q   ++   +     W  K
Sbjct: 181 SSVSKRTQNKVQKKFQKNIEEVRSLPKTDRFFKKVKFHGEPQKPPMNGYHKFHQDSWSSK 240

Query: 249 ALEQ---RKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSY 305
            ++    R+   EI R + Q+ P+   S++   KS   + ++Q K K D       P +Y
Sbjct: 241 EMQHLSVRERMVEIGRRW-QRIPQ---SQKDHFKSQAEELQKQYKVKLDLWLKTLSPENY 296

Query: 306 SLYCAELMANMKDVPST 322
           + Y     A  K++  T
Sbjct: 297 AAYKESTYAKGKNMAMT 313



 Score =  187 bits (474), Expect = 4e-47
 Identities = 136/415 (32%), Positives = 204/415 (49%), Gaps = 75/415 (18%)

Query: 352 KDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPV 411
           K++  E+ R L+ L      R  G  K L +  K+     +K       + G + PKRP+
Sbjct: 49  KNFSGEMCR-LKWLEISCNLRKFGTLKELVLEAKKCVKKMNKSQKY---RNGPDFPKRPL 104

Query: 412 SAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKP 471
           +A   F +E   Q  +  P +   ELT++L++ + +L E+ K KY         Q  RK 
Sbjct: 105 TAYNRFFKESWPQYSQMYPGMRSQELTKILSKKYRELPEQMKQKY--------IQDFRKE 156

Query: 472 GGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWI 531
             E EE+                      LARF+ +             ++ +K K   +
Sbjct: 157 KQEFEEK----------------------LARFREEHP-----------DLVQKAKKSSV 183

Query: 532 KKAAED--QKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELN 589
            K  ++  QK++++ + E+R+ P      KK+KF GEP+KPPMNGY KF Q+  S+ E+ 
Sbjct: 184 SKRTQNKVQKKFQKNIEEVRSLPKTDRFFKKVKFHGEPQKPPMNGYHKFHQDSWSSKEMQ 243

Query: 590 HLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYI 649
           HL ++ERMVEIG RWQRI QSQK+H+K  AEE QKQYKV LDLW+K+LSP++ AAYKE  
Sbjct: 244 HLSVRERMVEIGRRWQRIPQSQKDHFKSQAEELQKQYKVKLDLWLKTLSPENYAAYKEST 303

Query: 650 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
             K K+M    GP+P+  +   QS S              +  +E   E       G DS
Sbjct: 304 YAKGKNMAMTGGPDPRLKQADPQSSSA-------------KGLQEGFGEGQGLQAAGTDS 350

Query: 710 SES--SSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 762
           S++   +   S + +EN + D +++             E S+SS  SSG+  + D
Sbjct: 351 SQTIWVNCHVSMEPEENRKKDREKE-------------ESSNSSDCSSGEEIEVD 392



 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 56/242 (23%), Positives = 112/242 (46%), Gaps = 33/242 (13%)

Query: 194 DIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQR 253
           D P++P T    ++      Y ++ P   ++E+   L K++ +L ++ + K+I    +++
Sbjct: 98  DFPKRPLTAYNRFFKESWPQYSQMYPGMRSQELTKILSKKYRELPEQMKQKYIQDFRKEK 157

Query: 254 KEYEEIMRDYIQKHPEL--NISEEGITKSTLTKAERQL------------------KDKF 293
           +E+EE +  + ++HP+L     +  ++K T  K +++                   K KF
Sbjct: 158 QEFEEKLARFREEHPDLVQKAKKSSVSKRTQNKVQKKFQKNIEEVRSLPKTDRFFKKVKF 217

Query: 294 DGRPTKPPPNSYSLYCAELMAN--MKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKK 351
            G P KPP N Y  +  +  ++  M+ +   ERMV   ++W+ + Q +KD +  + ++ +
Sbjct: 218 HGEPQKPPMNGYHKFHQDSWSSKEMQHLSVRERMVEIGRRWQRIPQSQKDHFKSQAEELQ 277

Query: 352 KDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPV 411
           K Y+V+L  +L++L  E                K++T    K  A  GG     K   P 
Sbjct: 278 KQYKVKLDLWLKTLSPENYAAY-----------KESTYAKGKNMAMTGGPDPRLKQADPQ 326

Query: 412 SA 413
           S+
Sbjct: 327 SS 328


>gi|239753269 PREDICTED: upstream binding transcription factor, RNA
           polymerase I-like 6 [Homo sapiens]
          Length = 400

 Score =  244 bits (624), Expect = 2e-64
 Identities = 138/317 (43%), Positives = 201/317 (63%), Gaps = 11/317 (3%)

Query: 10  DLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCK 69
           D+++A P+ Q  WS  D+L LLECM+NNLP +D+  F +T+SHMDW KVAFK+FSG+MC+
Sbjct: 5   DIKVALPRSQGHWSNADILRLLECMENNLPYDDNGTFSSTQSHMDWGKVAFKNFSGEMCR 64

Query: 70  LKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAK 129
           LKW+EIS  +RKF TL +L+L+A++ VKN  K +K + HPDFPK+ LT Y RFF E   +
Sbjct: 65  LKWLEISCSLRKFSTLKKLVLEAKKCVKNTNKSQKGRNHPDFPKRLLTAYIRFFKENWPQ 124

Query: 130 YAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQN 189
           Y++++P M + ++TKILSKKYKELPE+ K K+IQDF++EKQEFE  LARFRE+HPDL Q 
Sbjct: 125 YSQMYPGMRSQEVTKILSKKYKELPEQMKQKHIQDFRKEKQEFEEKLARFREEHPDLDQK 184

Query: 190 AKKSDIPEKPKTP-QQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRL---KW 245
            KKSDI ++ +T  Q+    + ++V    + D   K+VK     Q   ++  ++     W
Sbjct: 185 GKKSDICKRVQTKVQKKVQKNIEEVRSLPKTDQFFKKVKFHGEPQKPPMNGYQKFHQDSW 244

Query: 246 IHKALEQ---RKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPP 302
             K L+    R+   EI R + Q+ P+   S++   KS     +++ K + D       P
Sbjct: 245 SSKELQHLSLRERMVEIGRRW-QRIPQ---SQKDHYKSQAELLQKEYKVELDLWLKTLSP 300

Query: 303 NSYSLYCAELMANMKDV 319
             Y+ Y     A  K++
Sbjct: 301 EDYAAYKESTYAKGKNM 317



 Score =  182 bits (462), Expect = 1e-45
 Identities = 125/363 (34%), Positives = 182/363 (50%), Gaps = 57/363 (15%)

Query: 378 KMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESEL 437
           K L +  K+     +K    + G+   + PKR ++A   F +E   Q  +  P +   E+
Sbjct: 81  KKLVLEAKKCVKNTNKS---QKGRNHPDFPKRLLTAYIRFFKENWPQYSQMYPGMRSQEV 137

Query: 438 TRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVI 497
           T++L++ + +L E+ K K+         Q  RK   E EE+                   
Sbjct: 138 TKILSKKYKELPEQMKQKH--------IQDFRKEKQEFEEK------------------- 170

Query: 498 GDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAED--QKRYERELSEMRAPPAAT 555
              LARF+ +             ++++K K   I K  +   QK+ ++ + E+R+ P   
Sbjct: 171 ---LARFREEHP-----------DLDQKGKKSDICKRVQTKVQKKVQKNIEEVRSLPKTD 216

Query: 556 NSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHY 615
              KK+KF GEP+KPPMNGYQKF Q+  S+ EL HL L+ERMVEIG RWQRI QSQK+HY
Sbjct: 217 QFFKKVKFHGEPQKPPMNGYQKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQSQKDHY 276

Query: 616 KKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKS 675
           K  AE  QK+YKV LDLW+K+LSP+D AAYKE    K K+M  + GP P   +T  QS S
Sbjct: 277 KSQAELLQKEYKVELDLWLKTLSPEDYAAYKESTYAKGKNMAMMGGPAPSLKQTDPQSSS 336

Query: 676 ES--EEDDEEDEDDEDEDEEEEDD---------ENGDSSEDGGDSSESSSEDESEDGDEN 724
               +E   E +  +    E             E  D+ +  G+  ESS+  +   G++ 
Sbjct: 337 AKGLQEGFGEGQGLQAAGTEASQTIWVNCQVSMEPEDNRKKDGEEEESSNSLDCSSGEDM 396

Query: 725 EED 727
           E D
Sbjct: 397 EVD 399



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 62/256 (24%), Positives = 118/256 (46%), Gaps = 40/256 (15%)

Query: 187 IQNAKKS-------DIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSD 239
           ++N  KS       D P++  T    ++      Y ++ P   ++EV   L K++ +L +
Sbjct: 91  VKNTNKSQKGRNHPDFPKRLLTAYIRFFKENWPQYSQMYPGMRSQEVTKILSKKYKELPE 150

Query: 240 KKRLKWIHKALEQRKEYEEIMRDYIQKHPELNIS--EEGITKSTLTKAERQL-------- 289
           + + K I    ++++E+EE +  + ++HP+L+    +  I K   TK ++++        
Sbjct: 151 QMKQKHIQDFRKEKQEFEEKLARFREEHPDLDQKGKKSDICKRVQTKVQKKVQKNIEEVR 210

Query: 290 ----------KDKFDGRPTKPPPNSYSLYCAELMAN--MKDVPSTERMVLCSQQWKLLSQ 337
                     K KF G P KPP N Y  +  +  ++  ++ +   ERMV   ++W+ + Q
Sbjct: 211 SLPKTDQFFKKVKFHGEPQKPPMNGYQKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQ 270

Query: 338 KEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQ 397
            +KD Y  + +  +K+Y+VEL  +L++L  E+               K++T    K  A 
Sbjct: 271 SQKDHYKSQAELLQKEYKVELDLWLKTLSPEDYAAY-----------KESTYAKGKNMAM 319

Query: 398 EGGKGGSEKPKRPVSA 413
            GG   S K   P S+
Sbjct: 320 MGGPAPSLKQTDPQSS 335


>gi|239741686 PREDICTED: upstream binding transcription factor, RNA
           polymerase I-like 6 [Homo sapiens]
          Length = 400

 Score =  244 bits (624), Expect = 2e-64
 Identities = 138/317 (43%), Positives = 201/317 (63%), Gaps = 11/317 (3%)

Query: 10  DLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCK 69
           D+++A P+ Q  WS  D+L LLECM+NNLP +D+  F +T+SHMDW KVAFK+FSG+MC+
Sbjct: 5   DIKVALPRSQGHWSNADILRLLECMENNLPYDDNGTFSSTQSHMDWGKVAFKNFSGEMCR 64

Query: 70  LKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAK 129
           LKW+EIS  +RKF TL +L+L+A++ VKN  K +K + HPDFPK+ LT Y RFF E   +
Sbjct: 65  LKWLEISCSLRKFSTLKKLVLEAKKCVKNTNKSQKGRNHPDFPKRLLTAYIRFFKENWPQ 124

Query: 130 YAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQN 189
           Y++++P M + ++TKILSKKYKELPE+ K K+IQDF++EKQEFE  LARFRE+HPDL Q 
Sbjct: 125 YSQMYPGMRSQEVTKILSKKYKELPEQMKQKHIQDFRKEKQEFEEKLARFREEHPDLDQK 184

Query: 190 AKKSDIPEKPKTP-QQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRL---KW 245
            KKSDI ++ +T  Q+    + ++V    + D   K+VK     Q   ++  ++     W
Sbjct: 185 GKKSDICKRVQTKVQKKVQKNIEEVRSLPKTDQFFKKVKFHGEPQKPPMNGYQKFHQDSW 244

Query: 246 IHKALEQ---RKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPP 302
             K L+    R+   EI R + Q+ P+   S++   KS     +++ K + D       P
Sbjct: 245 SSKELQHLSLRERMVEIGRRW-QRIPQ---SQKDHYKSQAELLQKEYKVELDLWLKTLSP 300

Query: 303 NSYSLYCAELMANMKDV 319
             Y+ Y     A  K++
Sbjct: 301 EDYAAYKESTYAKGKNM 317



 Score =  182 bits (462), Expect = 1e-45
 Identities = 125/363 (34%), Positives = 182/363 (50%), Gaps = 57/363 (15%)

Query: 378 KMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESEL 437
           K L +  K+     +K    + G+   + PKR ++A   F +E   Q  +  P +   E+
Sbjct: 81  KKLVLEAKKCVKNTNKS---QKGRNHPDFPKRLLTAYIRFFKENWPQYSQMYPGMRSQEV 137

Query: 438 TRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVI 497
           T++L++ + +L E+ K K+         Q  RK   E EE+                   
Sbjct: 138 TKILSKKYKELPEQMKQKH--------IQDFRKEKQEFEEK------------------- 170

Query: 498 GDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAED--QKRYERELSEMRAPPAAT 555
              LARF+ +             ++++K K   I K  +   QK+ ++ + E+R+ P   
Sbjct: 171 ---LARFREEHP-----------DLDQKGKKSDICKRVQTKVQKKVQKNIEEVRSLPKTD 216

Query: 556 NSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHY 615
              KK+KF GEP+KPPMNGYQKF Q+  S+ EL HL L+ERMVEIG RWQRI QSQK+HY
Sbjct: 217 QFFKKVKFHGEPQKPPMNGYQKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQSQKDHY 276

Query: 616 KKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKS 675
           K  AE  QK+YKV LDLW+K+LSP+D AAYKE    K K+M  + GP P   +T  QS S
Sbjct: 277 KSQAELLQKEYKVELDLWLKTLSPEDYAAYKESTYAKGKNMAMMGGPAPSLKQTDPQSSS 336

Query: 676 ES--EEDDEEDEDDEDEDEEEEDD---------ENGDSSEDGGDSSESSSEDESEDGDEN 724
               +E   E +  +    E             E  D+ +  G+  ESS+  +   G++ 
Sbjct: 337 AKGLQEGFGEGQGLQAAGTEASQTIWVNCQVSMEPEDNRKKDGEEEESSNSLDCSSGEDM 396

Query: 725 EED 727
           E D
Sbjct: 397 EVD 399



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 62/256 (24%), Positives = 118/256 (46%), Gaps = 40/256 (15%)

Query: 187 IQNAKKS-------DIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSD 239
           ++N  KS       D P++  T    ++      Y ++ P   ++EV   L K++ +L +
Sbjct: 91  VKNTNKSQKGRNHPDFPKRLLTAYIRFFKENWPQYSQMYPGMRSQEVTKILSKKYKELPE 150

Query: 240 KKRLKWIHKALEQRKEYEEIMRDYIQKHPELNIS--EEGITKSTLTKAERQL-------- 289
           + + K I    ++++E+EE +  + ++HP+L+    +  I K   TK ++++        
Sbjct: 151 QMKQKHIQDFRKEKQEFEEKLARFREEHPDLDQKGKKSDICKRVQTKVQKKVQKNIEEVR 210

Query: 290 ----------KDKFDGRPTKPPPNSYSLYCAELMAN--MKDVPSTERMVLCSQQWKLLSQ 337
                     K KF G P KPP N Y  +  +  ++  ++ +   ERMV   ++W+ + Q
Sbjct: 211 SLPKTDQFFKKVKFHGEPQKPPMNGYQKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQ 270

Query: 338 KEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQ 397
            +KD Y  + +  +K+Y+VEL  +L++L  E+               K++T    K  A 
Sbjct: 271 SQKDHYKSQAELLQKEYKVELDLWLKTLSPEDYAAY-----------KESTYAKGKNMAM 319

Query: 398 EGGKGGSEKPKRPVSA 413
            GG   S K   P S+
Sbjct: 320 MGGPAPSLKQTDPQSS 335


>gi|239747816 PREDICTED: upstream binding transcription factor, RNA
           polymerase I-like 6 [Homo sapiens]
          Length = 400

 Score =  244 bits (622), Expect = 3e-64
 Identities = 138/317 (43%), Positives = 200/317 (63%), Gaps = 11/317 (3%)

Query: 10  DLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCK 69
           D+++A P+ Q  WS  D+L LLECM+NNLP +D+  F +T+SHMDW KVAFK+FSG+MC+
Sbjct: 5   DIKVALPRSQGHWSNADILRLLECMENNLPYDDNGTFSSTQSHMDWGKVAFKNFSGEMCR 64

Query: 70  LKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAK 129
           LKW+EIS  +RKF TL +L+L+A++ VKN  K +K + HPDFPK+ LT Y RFF E   +
Sbjct: 65  LKWLEISCSLRKFSTLKKLVLEAKKCVKNTNKSQKGRNHPDFPKRLLTAYIRFFKENWPQ 124

Query: 130 YAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQN 189
           Y++++P M + ++TKILSKKYKELPE+ K K+IQDF++EKQEFE  LARFRE+HPDL Q 
Sbjct: 125 YSQMYPGMRSQEVTKILSKKYKELPEQMKQKHIQDFRKEKQEFEEKLARFREEHPDLDQK 184

Query: 190 AKKSDIPEKPKTP-QQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRL---KW 245
            KKSDI ++ +T  Q+    + ++V    + D   K+VK     Q   ++   +     W
Sbjct: 185 GKKSDICKRVQTKVQKKVQKNIEEVRSLPKTDQFFKKVKFHGEPQKPPMNGYHKFHQDSW 244

Query: 246 IHKALEQ---RKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPP 302
             K L+    R+   EI R + Q+ P+   S++   KS     +++ K + D       P
Sbjct: 245 SSKELQHLSLRERMVEIGRRW-QRIPQ---SQKDHYKSQAELLQKEYKVELDLWLKTLSP 300

Query: 303 NSYSLYCAELMANMKDV 319
             Y+ Y     A  K++
Sbjct: 301 EDYAAYKESTYAKGKNM 317



 Score =  179 bits (453), Expect = 1e-44
 Identities = 123/363 (33%), Positives = 181/363 (49%), Gaps = 57/363 (15%)

Query: 378 KMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESEL 437
           K L +  K+     +K    + G+   + PKR ++A   F +E   Q  +  P +   E+
Sbjct: 81  KKLVLEAKKCVKNTNKS---QKGRNHPDFPKRLLTAYIRFFKENWPQYSQMYPGMRSQEV 137

Query: 438 TRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVI 497
           T++L++ + +L E+ K K+         Q  RK   E EE+                   
Sbjct: 138 TKILSKKYKELPEQMKQKH--------IQDFRKEKQEFEEK------------------- 170

Query: 498 GDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAED--QKRYERELSEMRAPPAAT 555
              LARF+ +             ++++K K   I K  +   QK+ ++ + E+R+ P   
Sbjct: 171 ---LARFREEHP-----------DLDQKGKKSDICKRVQTKVQKKVQKNIEEVRSLPKTD 216

Query: 556 NSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHY 615
              KK+KF GEP+KPPMNGY KF Q+  S+ EL HL L+ERMVEIG RWQRI QSQK+HY
Sbjct: 217 QFFKKVKFHGEPQKPPMNGYHKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQSQKDHY 276

Query: 616 KKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKS 675
           K  AE  QK+YKV LDLW+K+LSP+D AAYKE    K K+M  + GP P   +T  QS S
Sbjct: 277 KSQAELLQKEYKVELDLWLKTLSPEDYAAYKESTYAKGKNMAMMGGPAPSLKQTDPQSSS 336

Query: 676 ES--EEDDEEDEDDEDEDEEEEDD---------ENGDSSEDGGDSSESSSEDESEDGDEN 724
               +E   E +  +    E             E  ++ +  G+  ESS+  +   G++ 
Sbjct: 337 AKGLQEGFGEGQGLQAAGTEASQTIWVNCQVSMEPEENRKKDGEEEESSNSLDCSSGEDM 396

Query: 725 EED 727
           E D
Sbjct: 397 EVD 399



 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 62/256 (24%), Positives = 118/256 (46%), Gaps = 40/256 (15%)

Query: 187 IQNAKKS-------DIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSD 239
           ++N  KS       D P++  T    ++      Y ++ P   ++EV   L K++ +L +
Sbjct: 91  VKNTNKSQKGRNHPDFPKRLLTAYIRFFKENWPQYSQMYPGMRSQEVTKILSKKYKELPE 150

Query: 240 KKRLKWIHKALEQRKEYEEIMRDYIQKHPELNIS--EEGITKSTLTKAERQL-------- 289
           + + K I    ++++E+EE +  + ++HP+L+    +  I K   TK ++++        
Sbjct: 151 QMKQKHIQDFRKEKQEFEEKLARFREEHPDLDQKGKKSDICKRVQTKVQKKVQKNIEEVR 210

Query: 290 ----------KDKFDGRPTKPPPNSYSLYCAELMAN--MKDVPSTERMVLCSQQWKLLSQ 337
                     K KF G P KPP N Y  +  +  ++  ++ +   ERMV   ++W+ + Q
Sbjct: 211 SLPKTDQFFKKVKFHGEPQKPPMNGYHKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQ 270

Query: 338 KEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQ 397
            +KD Y  + +  +K+Y+VEL  +L++L  E+               K++T    K  A 
Sbjct: 271 SQKDHYKSQAELLQKEYKVELDLWLKTLSPEDYAAY-----------KESTYAKGKNMAM 319

Query: 398 EGGKGGSEKPKRPVSA 413
            GG   S K   P S+
Sbjct: 320 MGGPAPSLKQTDPQSS 335


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 159/670 (23%), Positives = 254/670 (37%), Gaps = 120/670 (17%)

Query: 93  QEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKE 152
           QE  K+  K KK KK  DF +  +       +   A+  K   E   +  T+   +++  
Sbjct: 35  QEPQKSKGKKKKEKKKQDFDEDDILKELEE-LSLEAQGIKADRETVAVKPTENNEEEFTS 93

Query: 153 LPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKK 212
             +KKK +     + +KQ F+ N      D  +L     KS    KPK         +  
Sbjct: 94  KDKKKKGQ-----KGKKQSFDDN------DSEELEDKDSKSKKTAKPKVEMYSGSDDD-- 140

Query: 213 VYLKVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNI 272
                  D   K  K + GK     + K   KW         E +E     I++   +N 
Sbjct: 141 -------DDFNKLPKKAKGK-----AQKSNKKW------DGSEEDEDNSKKIKERSRINS 182

Query: 273 SEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQW 332
           S E   +S      R+ + K   +  KP PN  S        N  D  S          +
Sbjct: 183 SGESGDESDEFLQSRKGQKK--NQKNKPGPNIES-------GNEDDDAS----------F 223

Query: 333 KLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPE-----------EEQQRVLGEEKMLN 381
           K+ +  +K A  K+ ++KK+D E   LR L+   E           +E QR   EE +  
Sbjct: 224 KIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETV-- 281

Query: 382 INKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFS-EEKRRQLQEERPELSESELTRL 440
             K + T      PA E      EK + P +A      ++K++  ++++ E  E E    
Sbjct: 282 --KSKVTVDTGVIPASE------EKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKE---- 329

Query: 441 LARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDY 500
                    EKKK   KA   A++    +    E  ++ +  E  KR EE+  +    + 
Sbjct: 330 --------KEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEER 381

Query: 501 LARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKK 560
           L + K +R K     E       KKE  +  K   E + R E  L  ++A      S   
Sbjct: 382 LEQEKRERKKQ---KEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDS 438

Query: 561 MKFQGEPKKPPM---NGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKK 617
           +     PKK P+      +K  Q+L S      + L    VE+    Q + + ++     
Sbjct: 439 L-----PKKRPIYEDKKRKKIPQQLESKEVSESMELCAA-VEVME--QGVPEKEETPPPV 490

Query: 618 LAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSES 677
             EE++      LD W    S ++    +    NK     K    NP+            
Sbjct: 491 EPEEEEDTEDAGLDDWEAMASDEETEKVE---GNKVHIEVK---ENPE------------ 532

Query: 678 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDG---DENEEDDEDEDDD 734
           EE++EE+E++EDE+ EEE++E G+S    GD  +    DE + G   D+    +   D +
Sbjct: 533 EEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSE 592

Query: 735 EDDDEDEDNE 744
            D D+D   E
Sbjct: 593 YDSDDDRTKE 602


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 83.6 bits (205), Expect = 6e-16
 Identities = 119/614 (19%), Positives = 253/614 (41%), Gaps = 81/614 (13%)

Query: 156 KKKMKYIQDFQREKQ----EFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEK 211
           KK  +YI++  +E+     E  RN     E      +  +K  + E  K+  QL     K
Sbjct: 193 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELK 252

Query: 212 KVYLKVR---PDATTKEVKDSLGKQWSQLSD-----KKRLKWIHKALEQRKEYEEIMRDY 263
           +   + +   P   T  +++ + +Q  +L +     +K+ + + +  E+ +E E  MR+ 
Sbjct: 253 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ 312

Query: 264 IQK--HPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPS 321
            +K    E  + E+   +  L + E++L+++ + R  +           E M   ++   
Sbjct: 313 EEKMWRQEKRLREQ---EKELREQEKELREQKELREQE-----------EQMQEQEEKMW 358

Query: 322 TERMVLCSQQWKLLSQKEK----DAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEE 377
            +   +  Q+ K+  Q+E+    +   ++ +QK +D E  +    E L E+E+ R+  +E
Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE-RMREQE 417

Query: 378 KMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESEL 437
           KM     +Q      +K  QE  K   ++ ++      I   EK+ + +EE     E ++
Sbjct: 418 KMW----EQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKM 473

Query: 438 TRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVI 497
            +    MW    EK+  + +  E   K   + K   + E+  +  E  +  EE+W     
Sbjct: 474 QKQEENMWEQ-EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW----- 527

Query: 498 GDYLARFKNDRVKALKAMEMTWNNMEK---KEKLMWI------KKAAEDQKRYERELSEM 548
           G     ++ ++++  +  +  W   EK   +E+ MW       KK  E +K+   +  +M
Sbjct: 528 GQEKKMWRQEKMREQE--DQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKM 585

Query: 549 RAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRIS 608
           R         KKM+ +               +E++   E      +E+M E   +     
Sbjct: 586 REEERMREREKKMREE---------------EEMMREQEEKMQEQEEKMQEQEEKMWEQE 630

Query: 609 QSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKS-S 667
           +  +E  +K+ E+++K ++    +W +   P+ +    E+   K +   K++    K   
Sbjct: 631 EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH--EKMQEQEKMQEQEEKIWE 688

Query: 668 RTTLQSKSESEEDDEEDEDDEDEDEE---------EEDDENGDSSEDGGDSSESSSEDES 718
           +  ++ K++ +E    D++   E+E          EE++   +  E   +  E   E E 
Sbjct: 689 QEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 748

Query: 719 EDGDENEEDDEDED 732
           E  ++ E+  E E+
Sbjct: 749 EMWEQEEKMWEQEE 762



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 117/597 (19%), Positives = 250/597 (41%), Gaps = 75/597 (12%)

Query: 149 KYKELPEK--KKMKYIQDFQREKQEFERNLARFRE--DHPDLIQNAKKSDIPEKPKTPQQ 204
           K +E  EK  ++ K +++ ++E +E E+ L   +E  +  + +Q  ++    ++ K  +Q
Sbjct: 308 KMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQ 367

Query: 205 ---LWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMR 261
              +W   E+    + +     ++++D   + W Q  ++ R K      E+R   +E M 
Sbjct: 368 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ-DERLREK------EERMREQEKMW 420

Query: 262 DYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPS 321
           + ++K  E    +E   K+   + + Q +++   R  K             M   ++   
Sbjct: 421 EQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKK-------------MREEEETMR 467

Query: 322 TERMVLCSQQWKLLSQKEKDAYHKKC-DQKKKDYEVELLRFLESLPEEEQQRVLGEEKML 380
            +   +  Q+  +  Q+EK+   ++  +QK+K +E E ++  E    E+++++  +E+M 
Sbjct: 468 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 527

Query: 381 NINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRL 440
              KK       K   QE      E+  R         +E++   QEER E    E  + 
Sbjct: 528 GQEKKMWRQ--EKMREQEDQMWEQEEKMR--------DQEQKMWDQEERMEKKTQEQEK- 576

Query: 441 LARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESP--KRAEEIWQQSVIG 498
             + W D  EK + + + RE   K + E +   E+EE+ +  E    ++ E++W+Q    
Sbjct: 577 --KTW-DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE--- 630

Query: 499 DYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSS 558
               + +    K  +  E  W   EK    MW ++   +QK    E  +M+         
Sbjct: 631 ---EKMQEQEEKMWEQEEKMWEQEEK----MWEQQRLPEQKEKLWEHEKMQEQEKMQEQE 683

Query: 559 KKMKFQGEPKKPPMNGYQK-FSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKK 617
           +K+  Q + +K      +K + QE +          +E M E   + +   +  +E  +K
Sbjct: 684 EKIWEQEKMEKKTQEQEKKTWDQEKMRE--------EESMREREKKMREEEEMMREQEEK 735

Query: 618 LAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSES 677
           + E+++K  +   ++W      Q+   +++    + K   + R P  K      +   E 
Sbjct: 736 MQEQEEKMQEQEEEMW-----EQEEKMWEQ----EEKMWEQQRLPEQKEKLWEHEKMQEQ 786

Query: 678 EEDDEEDEDDEDEDEE---EEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 731
           E+  E++E   D++E+   +E+   G   +  G   +   ++E   G E +   ++E
Sbjct: 787 EKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE 843



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 79/392 (20%), Positives = 166/392 (42%), Gaps = 30/392 (7%)

Query: 357 ELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFI 416
           E+ R  E L E+E++    EEKM    +++      K   QE      EK  R       
Sbjct: 273 EMWRQEEELREQEKKIRKQEEKMWR-QEERLREQEGKMREQEEKMWRQEKRLR------- 324

Query: 417 FSEEKRRQLQEERPELSESELTRLLARMWNDLSEK---KKAKYKAREAALKAQSERKPGG 473
              E+ ++L+E+  EL E +  R       +  EK   ++ K + +E  +  Q ER    
Sbjct: 325 ---EQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 381

Query: 474 EREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKK 533
           E++ R +  +   + E +W+Q    D   R K +R   ++  E  W   E+ EK+   KK
Sbjct: 382 EKQMREQEQKMRDQEERMWEQ----DERLREKEER---MREQEKMW---EQVEKMREEKK 431

Query: 534 AAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPL 593
             E +K+   +  +M+         KKM+ + E  +      QK  + +    E      
Sbjct: 432 MQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ-- 489

Query: 594 KERMVEIGSR-WQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNK 652
           ++R+ E   + W++  +  +E  +K+ E+++K  +   ++W +      +   +E     
Sbjct: 490 QQRLPEQKEKLWEQ--EKMQEQEEKIWEQEEK-IRDQEEMWGQEKKMWRQEKMREQEDQM 546

Query: 653 RKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSES 712
            +   K+R    K      + + +++E +++  D E++  EEE     +      +    
Sbjct: 547 WEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR 606

Query: 713 SSEDESEDGDENEEDDEDEDDDEDDDEDEDNE 744
             E++ ++ +E  ++ E++  ++++   E  E
Sbjct: 607 EQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 85/448 (18%), Positives = 179/448 (39%), Gaps = 33/448 (7%)

Query: 127 RAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDL 186
           R +  K+  +  N+   +    + + LPE+K+  + Q+  +E++E          D  ++
Sbjct: 467 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 526

Query: 187 IQNAKKSDIPEKPKTPQ-QLWYTHEK----KVYLKVRPDATTKEVKDSLGKQWSQLSDKK 241
               KK    EK +  + Q+W   EK    +  +  + +   K+ ++   K W Q    +
Sbjct: 527 WGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMR 586

Query: 242 RLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPP 301
             + + +  ++ +E EE+MR+  +K  E    EE +         ++ ++K   +  K  
Sbjct: 587 EEERMREREKKMREEEEMMREQEEKMQE---QEEKM---------QEQEEKMWEQEEKMQ 634

Query: 302 PNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRF 361
                ++  E     ++    E+  L  Q+ KL   ++     K  +Q++K +E E +  
Sbjct: 635 EQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEK 694

Query: 362 LESLPEE---EQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFS 418
                E+   +Q+++  EE M    KK        +  +E  +   EK +     M+   
Sbjct: 695 KTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW--- 751

Query: 419 EEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREER 478
           E++ +  ++E     +  L     ++W     +++ K   +E  ++ Q E+  G E + R
Sbjct: 752 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR 811

Query: 479 GKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQ 538
           G+  +   + E++W Q        +      K     E  W   EK E+    K   +++
Sbjct: 812 GQEEKMRGQEEKMWGQE------EKMWGQEEKMWGQEEKMWGQEEKMEE----KMQGQEE 861

Query: 539 KRYERELSEMRAPPAATNSSKKMKFQGE 566
           K  E+E              +KM+ Q E
Sbjct: 862 KMREQEEKMRGQEEKMREQEEKMRGQEE 889



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 50/239 (20%), Positives = 102/239 (42%), Gaps = 44/239 (18%)

Query: 148 KKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLI-QNAKKSDIPEKPKTPQQLW 206
           K  K+  E++K  + Q+  RE++       + RE+   +  Q  K  +  EK +  ++  
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEM 750

Query: 207 YTHEKKVYLKVRPDATTKEVKDSLGKQWSQ--LSDKKRLKWIHKALEQRK---EYEEIMR 261
           +  E+K++             +   K W Q  L ++K   W H+ +++++   E EE MR
Sbjct: 751 WEQEEKMW-------------EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMR 797

Query: 262 DYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPS 321
           D  +K   +   EE +         R  ++K  G+  K       ++  E          
Sbjct: 798 DQEEK---MRGQEEKM---------RGQEEKMRGQEEKMWGQEEKMWGQE---------- 835

Query: 322 TERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKML 380
            E+M    Q+ K+  Q+EK     +  ++K   + E +R  E    E+++++ G+E+ +
Sbjct: 836 -EKM--WGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891


>gi|4504425 high-mobility group box 1 [Homo sapiens]
          Length = 215

 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 58/192 (30%), Positives = 90/192 (46%), Gaps = 28/192 (14%)

Query: 519 WNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKF 578
           W  M  KEK  +   A  D+ RYERE+     P   T   KK K    PK+PP + +  F
Sbjct: 49  WKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETK--KKFKDPNAPKRPP-SAFFLF 105

Query: 579 SQELLSN--GELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKS 636
             E      GE   L + +   ++G  W   +   K+ Y+K A + +++Y+         
Sbjct: 106 CSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYE--------- 156

Query: 637 LSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEED 696
              +D AAY+     K K       P+          KS+ ++++EEDE+DE+++EEEED
Sbjct: 157 ---KDIAAYRA----KGK-------PDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEED 202

Query: 697 DENGDSSEDGGD 708
           +E+ D  ED  D
Sbjct: 203 EEDEDEEEDDDD 214



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 55/194 (28%), Positives = 96/194 (49%), Gaps = 27/194 (13%)

Query: 400 GKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSE--SELTRLLARMWNDLSEKKKAKYK 457
           GKG  +KP+  +S+   F +  R + +++ P+ S   SE ++  +  W  +S K+K K++
Sbjct: 2   GKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFE 61

Query: 458 AREAALKAQSERK------PGGEREERGKLPESPKRAEEI-------WQQSVIGDYLARF 504
               A KA+ ER+      P GE +++ K P +PKR           ++  + G++    
Sbjct: 62  DMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLS 121

Query: 505 KNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRA---PPAA------T 555
             D  K L  M   WNN    +K  + KKAA+ +++YE++++  RA   P AA       
Sbjct: 122 IGDVAKKLGEM---WNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKA 178

Query: 556 NSSKKMKFQGEPKK 569
             SKK K + E ++
Sbjct: 179 EKSKKKKEEEEDEE 192



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 47/172 (27%), Positives = 73/172 (42%), Gaps = 38/172 (22%)

Query: 328 CSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA 387
           CS++WK +S KEK  +       K  YE E+  ++    E                KK+ 
Sbjct: 45  CSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGE---------------TKKKF 89

Query: 388 TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWND 447
             P +              PKRP SA F+F  E R +++ E P LS  ++ + L  MWN+
Sbjct: 90  KDPNA--------------PKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNN 135

Query: 448 LSEKKKAKYKAREAALKAQSER---------KPGGEREERGKLPESPKRAEE 490
            +   K  Y+ + A LK + E+         KP   ++   K  +S K+ EE
Sbjct: 136 TAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEE 187



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 41/188 (21%), Positives = 90/188 (47%), Gaps = 9/188 (4%)

Query: 106 KKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSN--LDLTKILSKKYKELPEKKKMKYIQ 163
           K  P  P+  ++ Y  F    R ++ K HP+ S    + +K  S+++K +  K+K K+  
Sbjct: 3   KGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFED 62

Query: 164 DFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVR---PD 220
             + +K  +ER +  +    P   +  KK   P  PK P   ++    +   K++   P 
Sbjct: 63  MAKADKARYEREMKTYI---PPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPG 119

Query: 221 ATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKS 280
            +  +V   LG+ W+  +   +  +  KA + +++YE+ +  Y  K  + + +++G+ K+
Sbjct: 120 LSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAK-GKPDAAKKGVVKA 178

Query: 281 TLTKAERQ 288
             +K +++
Sbjct: 179 EKSKKKKE 186



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 46/155 (29%), Positives = 72/155 (46%), Gaps = 12/155 (7%)

Query: 58  VAFKDFSGDMCKLKWVEIS-NEVRKFRTLTELILDAQEHVKNPY---KG--KKLKKHPDF 111
           V F +FS   C  +W  +S  E  KF  + +      E     Y   KG  KK  K P+ 
Sbjct: 36  VNFSEFS-KKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNA 94

Query: 112 PKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQE 171
           PK+P + +F F  E R K    HP +S  D+ K L + +       K  Y +   + K++
Sbjct: 95  PKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEK 154

Query: 172 FERNLARFR-EDHPDLIQNAKKSDI-PEKPKTPQQ 204
           +E+++A +R +  PD    AKK  +  EK K  ++
Sbjct: 155 YEKDIAAYRAKGKPDA---AKKGVVKAEKSKKKKE 186



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 39/175 (22%), Positives = 73/175 (41%), Gaps = 25/175 (14%)

Query: 211 KKVYLKVRPDATTK--EVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHP 268
           ++ + K  PDA+    E      ++W  +S K++ K+   A   +  YE  M+ YI    
Sbjct: 24  REEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPP-- 81

Query: 269 ELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMK----DVPSTER 324
                          K E + K K    P K PP+++ L+C+E    +K     +   + 
Sbjct: 82  ---------------KGETKKKFKDPNAP-KRPPSAFFLFCSEYRPKIKGEHPGLSIGDV 125

Query: 325 MVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRF-LESLPEEEQQRVLGEEK 378
                + W   +  +K  Y KK  + K+ YE ++  +  +  P+  ++ V+  EK
Sbjct: 126 AKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEK 180


>gi|194688135 high-mobility group box 2 [Homo sapiens]
          Length = 209

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 57/182 (31%), Positives = 86/182 (47%), Gaps = 25/182 (13%)

Query: 519 WNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKF 578
           W  M  KEK  +   A  D+ RY+RE+     PP      KK K    PK+PP + +  F
Sbjct: 49  WKTMSAKEKSKFEDMAKSDKARYDREMKNY-VPPKGDKKGKK-KDPNAPKRPP-SAFFLF 105

Query: 579 SQELLSNGELNH--LPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKS 636
             E     +  H  L + +   ++G  W   S   K+ Y++ A + +++Y+         
Sbjct: 106 CSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYE--------- 156

Query: 637 LSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEED 696
              +D AAY+     K KS    +GP     R T   K    ED+EE+E++EDEDEEEED
Sbjct: 157 ---KDIAAYRA----KGKSEAGKKGPG----RPTGSKKKNEPEDEEEEEEEEDEDEEEED 205

Query: 697 DE 698
           ++
Sbjct: 206 ED 207



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 34/163 (20%)

Query: 328 CSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA 387
           CS++WK +S KEK  +       K  Y+ E+  ++                         
Sbjct: 45  CSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYV------------------------- 79

Query: 388 TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWND 447
                 K  ++G K     PKRP SA F+F  E R +++ E P LS  +  + L  MW++
Sbjct: 80  ----PPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSE 135

Query: 448 LSEKKKAKYKAREAALKAQSER-----KPGGEREERGKLPESP 485
            S K K  Y+ + A LK + E+     +  G+ E   K P  P
Sbjct: 136 QSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRP 178



 Score = 60.1 bits (144), Expect = 8e-09
 Identities = 46/195 (23%), Positives = 94/195 (48%), Gaps = 28/195 (14%)

Query: 400 GKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSES--ELTRLLARMWNDLSEKKKAKYK 457
           GKG   KP+  +S+   F +  R + +++ P+ S +  E ++  +  W  +S K+K+K++
Sbjct: 2   GKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFE 61

Query: 458 AREAALKAQSERK------PGGEREERGKLPESPKRAEEIW-------QQSVIGDYLARF 504
               + KA+ +R+      P G+++ + K P +PKR    +       +  +  ++    
Sbjct: 62  DMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLS 121

Query: 505 KNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRA----------PPAA 554
             D  K L  M   W+    K+K  + +KAA+ +++YE++++  RA          P   
Sbjct: 122 IGDTAKKLGEM---WSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRP 178

Query: 555 TNSSKKMKFQGEPKK 569
           T S KK + + E ++
Sbjct: 179 TGSKKKNEPEDEEEE 193



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 40/189 (21%), Positives = 89/189 (47%), Gaps = 3/189 (1%)

Query: 106 KKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSN--LDLTKILSKKYKELPEKKKMKYIQ 163
           K  P+ P+  ++ Y  F    R ++ K HP+ S    + +K  S+++K +  K+K K+  
Sbjct: 3   KGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFED 62

Query: 164 DFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATT 223
             + +K  ++R +  +     D     K  + P++P +   L+ +  +       P  + 
Sbjct: 63  MAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSI 122

Query: 224 KEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLT 283
            +    LG+ WS+ S K +  +  KA + +++YE+ +  Y  K  +    ++G  + T +
Sbjct: 123 GDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAK-GKSEAGKKGPGRPTGS 181

Query: 284 KAERQLKDK 292
           K + + +D+
Sbjct: 182 KKKNEPEDE 190



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 49/169 (28%), Positives = 78/169 (46%), Gaps = 16/169 (9%)

Query: 50  ESHMDWEKVAFKDFSGDMCKLKWVEIS-NEVRKFRTLTELILDAQEH-VKN--PYKGKKL 105
           + H D   V F +FS   C  +W  +S  E  KF  + +      +  +KN  P KG K 
Sbjct: 29  KKHPD-SSVNFAEFS-KKCSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPPKGDKK 86

Query: 106 --KKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQ 163
             KK P+ PK+P + +F F  E R K    HP +S  D  K L + + E   K K  Y Q
Sbjct: 87  GKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQ 146

Query: 164 DFQREKQEFERNLARFR--------EDHPDLIQNAKKSDIPEKPKTPQQ 204
              + K+++E+++A +R        +  P     +KK + PE  +  ++
Sbjct: 147 KAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTGSKKKNEPEDEEEEEE 195



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 48/234 (20%), Positives = 90/234 (38%), Gaps = 57/234 (24%)

Query: 211 KKVYLKVRPDATTK--EVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHP 268
           ++ + K  PD++    E      ++W  +S K++ K+   A   +  Y+  M++Y+    
Sbjct: 24  REEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPP-- 81

Query: 269 ELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMK------DVPST 322
                          K +++ K K    P K PP+++ L+C+E    +K       +  T
Sbjct: 82  ---------------KGDKKGKKKDPNAP-KRPPSAFFLFCSEHRPKIKSEHPGLSIGDT 125

Query: 323 ERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNI 382
            + +   + W   S K+K  Y +K  + K+ YE ++  +                     
Sbjct: 126 AKKL--GEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAY--------------------- 162

Query: 383 NKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESE 436
            + +  S A KK    G   GS+K   P        EE+  +  E+  E  E E
Sbjct: 163 -RAKGKSEAGKK--GPGRPTGSKKKNEPED-----EEEEEEEEDEDEEEEDEDE 208


>gi|194688133 high-mobility group box 2 [Homo sapiens]
          Length = 209

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 57/182 (31%), Positives = 86/182 (47%), Gaps = 25/182 (13%)

Query: 519 WNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKF 578
           W  M  KEK  +   A  D+ RY+RE+     PP      KK K    PK+PP + +  F
Sbjct: 49  WKTMSAKEKSKFEDMAKSDKARYDREMKNY-VPPKGDKKGKK-KDPNAPKRPP-SAFFLF 105

Query: 579 SQELLSNGELNH--LPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKS 636
             E     +  H  L + +   ++G  W   S   K+ Y++ A + +++Y+         
Sbjct: 106 CSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYE--------- 156

Query: 637 LSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEED 696
              +D AAY+     K KS    +GP     R T   K    ED+EE+E++EDEDEEEED
Sbjct: 157 ---KDIAAYRA----KGKSEAGKKGPG----RPTGSKKKNEPEDEEEEEEEEDEDEEEED 205

Query: 697 DE 698
           ++
Sbjct: 206 ED 207



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 34/163 (20%)

Query: 328 CSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA 387
           CS++WK +S KEK  +       K  Y+ E+  ++                         
Sbjct: 45  CSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYV------------------------- 79

Query: 388 TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWND 447
                 K  ++G K     PKRP SA F+F  E R +++ E P LS  +  + L  MW++
Sbjct: 80  ----PPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSE 135

Query: 448 LSEKKKAKYKAREAALKAQSER-----KPGGEREERGKLPESP 485
            S K K  Y+ + A LK + E+     +  G+ E   K P  P
Sbjct: 136 QSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRP 178



 Score = 60.1 bits (144), Expect = 8e-09
 Identities = 46/195 (23%), Positives = 94/195 (48%), Gaps = 28/195 (14%)

Query: 400 GKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSES--ELTRLLARMWNDLSEKKKAKYK 457
           GKG   KP+  +S+   F +  R + +++ P+ S +  E ++  +  W  +S K+K+K++
Sbjct: 2   GKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFE 61

Query: 458 AREAALKAQSERK------PGGEREERGKLPESPKRAEEIW-------QQSVIGDYLARF 504
               + KA+ +R+      P G+++ + K P +PKR    +       +  +  ++    
Sbjct: 62  DMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLS 121

Query: 505 KNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRA----------PPAA 554
             D  K L  M   W+    K+K  + +KAA+ +++YE++++  RA          P   
Sbjct: 122 IGDTAKKLGEM---WSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRP 178

Query: 555 TNSSKKMKFQGEPKK 569
           T S KK + + E ++
Sbjct: 179 TGSKKKNEPEDEEEE 193



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 40/189 (21%), Positives = 89/189 (47%), Gaps = 3/189 (1%)

Query: 106 KKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSN--LDLTKILSKKYKELPEKKKMKYIQ 163
           K  P+ P+  ++ Y  F    R ++ K HP+ S    + +K  S+++K +  K+K K+  
Sbjct: 3   KGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFED 62

Query: 164 DFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATT 223
             + +K  ++R +  +     D     K  + P++P +   L+ +  +       P  + 
Sbjct: 63  MAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSI 122

Query: 224 KEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLT 283
            +    LG+ WS+ S K +  +  KA + +++YE+ +  Y  K  +    ++G  + T +
Sbjct: 123 GDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAK-GKSEAGKKGPGRPTGS 181

Query: 284 KAERQLKDK 292
           K + + +D+
Sbjct: 182 KKKNEPEDE 190



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 49/169 (28%), Positives = 78/169 (46%), Gaps = 16/169 (9%)

Query: 50  ESHMDWEKVAFKDFSGDMCKLKWVEIS-NEVRKFRTLTELILDAQEH-VKN--PYKGKKL 105
           + H D   V F +FS   C  +W  +S  E  KF  + +      +  +KN  P KG K 
Sbjct: 29  KKHPD-SSVNFAEFS-KKCSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPPKGDKK 86

Query: 106 --KKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQ 163
             KK P+ PK+P + +F F  E R K    HP +S  D  K L + + E   K K  Y Q
Sbjct: 87  GKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQ 146

Query: 164 DFQREKQEFERNLARFR--------EDHPDLIQNAKKSDIPEKPKTPQQ 204
              + K+++E+++A +R        +  P     +KK + PE  +  ++
Sbjct: 147 KAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTGSKKKNEPEDEEEEEE 195



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 48/234 (20%), Positives = 90/234 (38%), Gaps = 57/234 (24%)

Query: 211 KKVYLKVRPDATTK--EVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHP 268
           ++ + K  PD++    E      ++W  +S K++ K+   A   +  Y+  M++Y+    
Sbjct: 24  REEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPP-- 81

Query: 269 ELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMK------DVPST 322
                          K +++ K K    P K PP+++ L+C+E    +K       +  T
Sbjct: 82  ---------------KGDKKGKKKDPNAP-KRPPSAFFLFCSEHRPKIKSEHPGLSIGDT 125

Query: 323 ERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNI 382
            + +   + W   S K+K  Y +K  + K+ YE ++  +                     
Sbjct: 126 AKKL--GEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAY--------------------- 162

Query: 383 NKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESE 436
            + +  S A KK    G   GS+K   P        EE+  +  E+  E  E E
Sbjct: 163 -RAKGKSEAGKK--GPGRPTGSKKKNEPED-----EEEEEEEEDEDEEEEDEDE 208


>gi|11321591 high-mobility group box 2 [Homo sapiens]
          Length = 209

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 57/182 (31%), Positives = 86/182 (47%), Gaps = 25/182 (13%)

Query: 519 WNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKF 578
           W  M  KEK  +   A  D+ RY+RE+     PP      KK K    PK+PP + +  F
Sbjct: 49  WKTMSAKEKSKFEDMAKSDKARYDREMKNY-VPPKGDKKGKK-KDPNAPKRPP-SAFFLF 105

Query: 579 SQELLSNGELNH--LPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKS 636
             E     +  H  L + +   ++G  W   S   K+ Y++ A + +++Y+         
Sbjct: 106 CSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYE--------- 156

Query: 637 LSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEED 696
              +D AAY+     K KS    +GP     R T   K    ED+EE+E++EDEDEEEED
Sbjct: 157 ---KDIAAYRA----KGKSEAGKKGPG----RPTGSKKKNEPEDEEEEEEEEDEDEEEED 205

Query: 697 DE 698
           ++
Sbjct: 206 ED 207



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 34/163 (20%)

Query: 328 CSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA 387
           CS++WK +S KEK  +       K  Y+ E+  ++                         
Sbjct: 45  CSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYV------------------------- 79

Query: 388 TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWND 447
                 K  ++G K     PKRP SA F+F  E R +++ E P LS  +  + L  MW++
Sbjct: 80  ----PPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSE 135

Query: 448 LSEKKKAKYKAREAALKAQSER-----KPGGEREERGKLPESP 485
            S K K  Y+ + A LK + E+     +  G+ E   K P  P
Sbjct: 136 QSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRP 178



 Score = 60.1 bits (144), Expect = 8e-09
 Identities = 46/195 (23%), Positives = 94/195 (48%), Gaps = 28/195 (14%)

Query: 400 GKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSES--ELTRLLARMWNDLSEKKKAKYK 457
           GKG   KP+  +S+   F +  R + +++ P+ S +  E ++  +  W  +S K+K+K++
Sbjct: 2   GKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFE 61

Query: 458 AREAALKAQSERK------PGGEREERGKLPESPKRAEEIW-------QQSVIGDYLARF 504
               + KA+ +R+      P G+++ + K P +PKR    +       +  +  ++    
Sbjct: 62  DMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLS 121

Query: 505 KNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRA----------PPAA 554
             D  K L  M   W+    K+K  + +KAA+ +++YE++++  RA          P   
Sbjct: 122 IGDTAKKLGEM---WSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRP 178

Query: 555 TNSSKKMKFQGEPKK 569
           T S KK + + E ++
Sbjct: 179 TGSKKKNEPEDEEEE 193



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 40/189 (21%), Positives = 89/189 (47%), Gaps = 3/189 (1%)

Query: 106 KKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSN--LDLTKILSKKYKELPEKKKMKYIQ 163
           K  P+ P+  ++ Y  F    R ++ K HP+ S    + +K  S+++K +  K+K K+  
Sbjct: 3   KGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFED 62

Query: 164 DFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATT 223
             + +K  ++R +  +     D     K  + P++P +   L+ +  +       P  + 
Sbjct: 63  MAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSI 122

Query: 224 KEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLT 283
            +    LG+ WS+ S K +  +  KA + +++YE+ +  Y  K  +    ++G  + T +
Sbjct: 123 GDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAK-GKSEAGKKGPGRPTGS 181

Query: 284 KAERQLKDK 292
           K + + +D+
Sbjct: 182 KKKNEPEDE 190



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 49/169 (28%), Positives = 78/169 (46%), Gaps = 16/169 (9%)

Query: 50  ESHMDWEKVAFKDFSGDMCKLKWVEIS-NEVRKFRTLTELILDAQEH-VKN--PYKGKKL 105
           + H D   V F +FS   C  +W  +S  E  KF  + +      +  +KN  P KG K 
Sbjct: 29  KKHPD-SSVNFAEFS-KKCSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPPKGDKK 86

Query: 106 --KKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQ 163
             KK P+ PK+P + +F F  E R K    HP +S  D  K L + + E   K K  Y Q
Sbjct: 87  GKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQ 146

Query: 164 DFQREKQEFERNLARFR--------EDHPDLIQNAKKSDIPEKPKTPQQ 204
              + K+++E+++A +R        +  P     +KK + PE  +  ++
Sbjct: 147 KAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTGSKKKNEPEDEEEEEE 195



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 48/234 (20%), Positives = 90/234 (38%), Gaps = 57/234 (24%)

Query: 211 KKVYLKVRPDATTK--EVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHP 268
           ++ + K  PD++    E      ++W  +S K++ K+   A   +  Y+  M++Y+    
Sbjct: 24  REEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPP-- 81

Query: 269 ELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMK------DVPST 322
                          K +++ K K    P K PP+++ L+C+E    +K       +  T
Sbjct: 82  ---------------KGDKKGKKKDPNAP-KRPPSAFFLFCSEHRPKIKSEHPGLSIGDT 125

Query: 323 ERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNI 382
            + +   + W   S K+K  Y +K  + K+ YE ++  +                     
Sbjct: 126 AKKL--GEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAY--------------------- 162

Query: 383 NKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESE 436
            + +  S A KK    G   GS+K   P        EE+  +  E+  E  E E
Sbjct: 163 -RAKGKSEAGKK--GPGRPTGSKKKNEPED-----EEEEEEEEDEDEEEEDEDE 208


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 144/734 (19%), Positives = 300/734 (40%), Gaps = 101/734 (13%)

Query: 92   AQEHVKNPYKGKKLKKHPDF---PKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSK 148
            AQ+      +G+KL +  +     +K L   +     +  K AK   +++  ++  IL++
Sbjct: 1638 AQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLA--EVKNILAQ 1695

Query: 149  KYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYT 208
            K +ELP+++     Q+   +++E  + L     D  +L    ++ +  E     ++    
Sbjct: 1696 KVEELPQRE-----QNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLA 1750

Query: 209  HEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHP 268
             E++     R   + +E K  L ++   L  +K     HK  E+  E EE          
Sbjct: 1751 EEEEALAWQREKLSEEETK--LAQEEELLIQEKEKLAQHK--EKMPEEEE---------- 1796

Query: 269  ELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLC 328
             L    E + +  +  A++  ++++     +   N   LY  + +A  K   + E+  L 
Sbjct: 1797 RLGRKREQLIEKKMKLAQK--RERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLA 1854

Query: 329  SQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQAT 388
             ++  LL  KE+  + KK   + K+   +L  F + L + E++  L +EK   I KK+  
Sbjct: 1855 QRKENLLYNKERLTHSKKQLVQVKN---KLGMFNKILAQVEEK--LTQEKETVIKKKEKL 1909

Query: 389  SPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEE-RPELSESELTRLLARMWND 447
            +   KK  Q       ++ K     M +  E+   Q ++  R EL  ++  + L      
Sbjct: 1910 AETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKR 1969

Query: 448  LSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKND 507
            L+E+K    + +E   K        GE  E  +  +  +  +E++++ +  +       D
Sbjct: 1970 LAEEKMRLVEGKETLSK--------GETPETSRQRKMTQVEQELFERKLSLEEKILLHED 2021

Query: 508  RVKALKAMEMTWNNME----KKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKM-- 561
            R+ A++  E+    +E    ++  +   +K A+  ++  ++   +   PA  N   K   
Sbjct: 2022 RILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQ 2081

Query: 562  -------KFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKE-----RMVEIGSRWQRISQ 609
                   K   E  K        F +E   + E + L +KE     +  E+    +++++
Sbjct: 2082 KLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLAR 2141

Query: 610  SQKE----------HYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKE-----YISNK-R 653
             Q++            +K+ EE+ K  + H ++    L  ++    +E     ++  + R
Sbjct: 2142 KQRKLANKMRRMINKEEKMTEEESKLARKHSEV---ILDDEEEGGIEEEEVIPFLKRRWR 2198

Query: 654  KSMTKLRGPNPKSSRTTLQSKSESEE---------------------DDEEDEDDEDEDE 692
            K     RG  PK   ++   + ESEE                     ++EE+ ++E+E E
Sbjct: 2199 KRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEERE 2258

Query: 693  EE---EDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSS 749
            EE   E++E     E+G +      E+E +   + ++ +E ++ +E  +E E+  SE  +
Sbjct: 2259 EEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEET 2318

Query: 750  SSSSSSGDSSDSDS 763
             S S   +  +S S
Sbjct: 2319 ESLSDEEEEEESCS 2332



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 125/672 (18%), Positives = 268/672 (39%), Gaps = 110/672 (16%)

Query: 124  MEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQ--REKQEFERNLARFRE 181
            ME+ + Y++     S + L+K +  + K++ +      ++  Q  R+K++ +    + ++
Sbjct: 1131 MEEASVYSQWSSSTSVIKLSKDVDSQEKDISKDHIALTLKRLQKIRDKRDKKATAQKLKK 1190

Query: 182  DHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKK 241
             H    +  K++ +  +  TP  +     KKV ++ R  +     + + G   S   D  
Sbjct: 1191 KHK---KKGKEAKVINEETTPPVMEQPVTKKVKIQGRGASGISGRRSTAGDGSSWRDDLC 1247

Query: 242  RLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPP 301
            RL  +  +  Q K                    E +    +T A+  L D+         
Sbjct: 1248 RLMALRISGSQTK------------------MSENLNAELVTFAQEMLVDRHP------- 1282

Query: 302  PNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKK---KDYEVEL 358
              S+ L+  E+   +K      +++L    W ++  ++K  + ++   ++   +    E+
Sbjct: 1283 --SWELF-QEICPLLK---KESKVLLEDLDWDVVPPEKKPIFIQEGAIREDMIQGVTQEV 1336

Query: 359  LRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPA-QEGGK--GGSEKPKRPVSAMF 415
            +R  E +P EE+Q       ML + + Q      KK    E G    G E  K+     F
Sbjct: 1337 IRHKEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTF 1396

Query: 416  IFS-EEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQS-----ER 469
              S ++ R+ +Q+ER      ++ R + +   D+SE+ +      E  +K +      ER
Sbjct: 1397 QKSPKQGRKAVQKER---KVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIER 1453

Query: 470  KPGGE---------REERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWN 520
             P  +         ++  G+  +S K  +E W++ ++ +     +    +A + +     
Sbjct: 1454 TPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQE-----EEKLHQAGEKLSPEEE 1508

Query: 521  NMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQ 580
             +++ +KL W     E ++ +E  LS         + SK+ +++ E +           +
Sbjct: 1509 MLQEDKKLKW----EEWKQVWENMLS---------SKSKEQQYKDEEE-------VTLEE 1548

Query: 581  ELLSNGELNHLPLKE--RMVEIGSRWQRISQSQKEHYKKLAEEQQK--QYKVHLDLWVKS 636
            E+   GE     + E  R ++   +W RI + +    KK A+E++K  Q +  L    + 
Sbjct: 1549 EVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQ 1608

Query: 637  LSPQDRAAYKEY--ISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDE---- 690
            L+ ++R   + Y  I+   + M +  G   +   T  Q   +  ++ E+      +    
Sbjct: 1609 LAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKK 1668

Query: 691  ------DEEEEDDENGDSSEDGGDSSESSSE----DESEDGDENEEDDEDEDDDEDDD-- 738
                  +EE+   + G  +E     ++   E    +++ D  E E   E E+ + D +  
Sbjct: 1669 WEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEEL 1728

Query: 739  ---EDEDNESEG 747
               E+E N+ EG
Sbjct: 1729 SWKEEELNQEEG 1740



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 81/358 (22%), Positives = 156/358 (43%), Gaps = 43/358 (12%)

Query: 121  RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR 180
            R F++ + K AK   ++  +   + LSK+  +L   K +K +Q   R++++  +   +  
Sbjct: 2043 RIFVQGQRKLAKASRKL--IKKRESLSKEPAKL--NKILKALQKLTRDERKLTQEEIKMT 2098

Query: 181  EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDK 240
            +    L    ++  I E+ K   + W   EK+  L       TK+ K  L ++  +L++K
Sbjct: 2099 KMKRALFVKERRLSI-EQSKLDIKEWDFSEKRSEL-------TKDEK-KLARKQRKLANK 2149

Query: 241  KRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEE---GITKSTLTK-AERQLKDKFDGR 296
             R + I+K  +  +E  ++ R    KH E+ + +E   GI +  +    +R+ + + + +
Sbjct: 2150 MR-RMINKEEKMTEEESKLAR----KHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAK 2204

Query: 297  PTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEV 356
                P   +S       + + +V S E      +   LL + EK       ++++++ E 
Sbjct: 2205 RGDKPKEKFS-------SQVDEVESEEHF--SEEMESLLDELEKQESLSSEEEEEREEEE 2255

Query: 357  ELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFI 416
            E  R  E + EEE++R   EE      +KQ      +K  +E  K   EK K  V     
Sbjct: 2256 E--REEEEVREEEEERKEEEEG----EEKQV-----EKEEEEKKKKKKEKKKEEVQEKEE 2304

Query: 417  FSEEKRRQLQEERPE-LSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGG 473
              EEK   + EE  E LS+ E       +  ++  +K+   K ++  L+ Q  +   G
Sbjct: 2305 VFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRG 2362



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 65/329 (19%), Positives = 132/329 (40%), Gaps = 45/329 (13%)

Query: 330  QQWK-----LLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINK 384
            ++WK     +LS K K+       Q K + EV L        EEE  R  GEEK   + +
Sbjct: 1519 EEWKQVWENMLSSKSKE------QQYKDEEEVTL--------EEEVSR-EGEEKEQQVTE 1563

Query: 385  KQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARM 444
            +Q       K A+   K    + KR      +  EE++   +E +    E +L +   ++
Sbjct: 1564 EQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKI 1623

Query: 445  WNDLSEKKKA--KYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQ-------- 494
              D  E  +A  K+  +E  L  + E+      +E  KL +  K+  + W++        
Sbjct: 1624 TQDDREMAQAEGKFAQKEETLAQRGEKL----SQEAEKLAQKRKKLAKKWEKVAREEEKL 1679

Query: 495  SVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAA 554
            +  G  LA  KN   + ++ +     N++ +E     K+ A++ +  E ++ E+      
Sbjct: 1680 AKKGGKLAEVKNILAQKVEELPQREQNLDWQE-----KELAQELEELEWDMEELSWKEEE 1734

Query: 555  TNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEH 614
             N  +    + + K         + +E LS  E      +E +++   +  +  +   E 
Sbjct: 1735 LNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEE 1794

Query: 615  YKKLAEEQQKQYKVHLDL------WVKSL 637
             ++L  ++++  +  + L      W+ S+
Sbjct: 1795 EERLGRKREQLIEKKMKLAQKRERWINSM 1823


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 33/90 (36%), Positives = 61/90 (67%), Gaps = 8/90 (8%)

Query: 665 KSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD--------SSESSSED 716
           K++     S+ E +EDDE+DEDD+D++E++ ++E  +++   G          +++ +ED
Sbjct: 176 KAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAED 235

Query: 717 ESEDGDENEEDDEDEDDDEDDDEDEDNESE 746
           E E+ D+ +EDD+D++DDEDDD+++D E E
Sbjct: 236 EDEEEDDEDEDDDDDEDDEDDDDEDDEEEE 265



 Score = 76.6 bits (187), Expect = 8e-14
 Identities = 36/94 (38%), Positives = 58/94 (61%), Gaps = 12/94 (12%)

Query: 664 PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSS--------- 714
           P + +    + +  +EDDE+DEDDED+D++EEDD   ++ E      + ++         
Sbjct: 172 PAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKN 231

Query: 715 --EDESEDGDENEEDDEDEDDDEDDDEDEDNESE 746
             EDE E+ D+ +EDD+D++DDED D+DED+E E
Sbjct: 232 VAEDEDEEEDDEDEDDDDDEDDED-DDDEDDEEE 264



 Score = 73.9 bits (180), Expect = 5e-13
 Identities = 33/97 (34%), Positives = 60/97 (61%), Gaps = 3/97 (3%)

Query: 646 KEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSED 705
           K  ++   K    +     K+ +   +  S+ EEDD+ +ED+ED+++E+ED++  + +  
Sbjct: 116 KALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAM 175

Query: 706 GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDED 742
              ++  +SEDE    DE++EDDED+DDDE+DD +E+
Sbjct: 176 KAAAAAPASEDED---DEDDEDDEDDDDDEEDDSEEE 209



 Score = 73.2 bits (178), Expect = 9e-13
 Identities = 42/134 (31%), Positives = 63/134 (47%), Gaps = 34/134 (25%)

Query: 661 GPNPKSSRTTLQSKSESEEDDEEDED-DEDEDE---------------EEEDDENGDSSE 704
           G N K   +  +   +SEED+E+DED DEDEDE               E+EDDE+ +  E
Sbjct: 137 GKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDE 196

Query: 705 DGGDSSESSSEDESEDGDE------------------NEEDDEDEDDDEDDDEDEDNESE 746
           D  D  E  SE+E+ +                      +ED+E++D+DEDDD+DED+E +
Sbjct: 197 DDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDD 256

Query: 747 GSSSSSSSSGDSSD 760
                     +  +
Sbjct: 257 DDEDDEEEEEEEEE 270



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 22/55 (40%), Positives = 35/55 (63%), Gaps = 2/55 (3%)

Query: 710 SESSSEDESEDGDENEEDD--EDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 762
           +++    + ED DE E+DD  EDE+DDED+DEDED     +  +++++  S D D
Sbjct: 134 AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDED 188



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 18/58 (31%), Positives = 36/58 (62%)

Query: 707 GDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
           G +++    DE ED D  E++++DED+DED+DE E    + ++++ +S  +  + D +
Sbjct: 137 GKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDED 194



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 22/97 (22%), Positives = 50/97 (51%), Gaps = 24/97 (24%)

Query: 651 NKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSS 710
           ++ ++M        K+++          ED++E+EDDEDED+++++D             
Sbjct: 206 SEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDED------------- 252

Query: 711 ESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEG 747
                      DE+++D++DE+++E+++E+   E+ G
Sbjct: 253 -----------DEDDDDEDDEEEEEEEEEEPVKEAPG 278



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 19/56 (33%), Positives = 37/56 (66%), Gaps = 1/56 (1%)

Query: 708 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDE-DNESEGSSSSSSSSGDSSDSD 762
           +   +  ED  E+ D++ E+DE++D+DED+DEDE +  +  +++++ +S D  D D
Sbjct: 136 NGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDED 191



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 18/58 (31%), Positives = 35/58 (60%), Gaps = 2/58 (3%)

Query: 664 PKSSRTTLQSKSESEEDDEEDEDDE--DEDEEEEDDENGDSSEDGGDSSESSSEDESE 719
           P  ++   + + E E+D++ED+DD+  DED+++EDDE  +  E+     E+  + + E
Sbjct: 226 PVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKE 283



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 14/47 (29%), Positives = 31/47 (65%)

Query: 672 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDES 718
           + + + +++D+ED+DDED++EEEE++E     E  G   +  ++ ++
Sbjct: 243 EDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKA 289



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 15/50 (30%), Positives = 30/50 (60%)

Query: 676 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE 725
           + +EDDE+D+D++DE+EEEE++E       G    E + +  + +  + +
Sbjct: 248 DDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQK 297


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score = 77.4 bits (189), Expect = 5e-14
 Identities = 43/120 (35%), Positives = 66/120 (55%), Gaps = 8/120 (6%)

Query: 645 YKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGD--- 701
           Y+E +      +T L G + +  +    S +E +  DEE+ED+E EDEE+EDDE+G+   
Sbjct: 131 YRESVFKLLPQLTYLDGYD-REDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEE 189

Query: 702 -SSEDGGDSSESSSEDESEDGDENEE---DDEDEDDDEDDDEDEDNESEGSSSSSSSSGD 757
              ED  D      ED+ E  +E EE   D+EDED+DED++E+E  + E     +   G+
Sbjct: 190 FDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGE 249



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 4/78 (5%)

Query: 691 DEEEEDDENGDSSEDGGDSSESSSE--DESEDGDENEEDDE-DEDDDEDDDEDEDNESEG 747
           D E+++  + D+  DG D  E   E  DE ++ DE+ E++E DE+DDED+D + D + + 
Sbjct: 149 DREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDE 208

Query: 748 SSSSSSSSG-DSSDSDSN 764
            S      G D  D D +
Sbjct: 209 VSEEEEEFGLDEEDEDED 226



 Score = 37.7 bits (86), Expect = 0.040
 Identities = 14/60 (23%), Positives = 31/60 (51%)

Query: 705 DGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
           DG D  +  + D   + D  +E++EDE+ ++++DED+++  E          +  + D +
Sbjct: 146 DGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDED 205


>gi|239744307 PREDICTED: similar to hCG1991922 [Homo sapiens]
          Length = 486

 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 55/202 (27%), Positives = 91/202 (45%), Gaps = 30/202 (14%)

Query: 519 WNNMEKKEKLMWIKK-------AAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPP 571
           W NM  KEK  + +        A  D+  Y+RE+     P   T   KK K    PK+PP
Sbjct: 178 WKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGETK--KKFKDPNAPKRPP 235

Query: 572 MNGYQKFSQELLS-NGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHL 630
              +  FS+      GE   L   +   ++G  W   +   K+ Y+K + + +++Y+   
Sbjct: 236 SAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKRSAKLKEKYE--- 292

Query: 631 DLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDE 690
                    +D AAY+        +  K    N    +     K + EE++EEDE+DE+E
Sbjct: 293 ---------KDIAAYR--------AKGKHDAANNGVVKAAKSKKKKEEEENEEDEEDEEE 335

Query: 691 DEEEEDDENGDSSEDGGDSSES 712
           +++E++DE  D  E+ GD  +S
Sbjct: 336 EKDEDEDEEDDEDEEDGDDEQS 357



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 22/142 (15%)

Query: 328 CSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA 387
           CS++WK +S KEK  + +   +             E + + ++     E K   I  K  
Sbjct: 174 CSERWKNMSAKEKGKFGRARGK------------FEDMAKADKAHYKREMKTY-IPPKGE 220

Query: 388 TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWND 447
           T    K P           PKRP SA F++  E   +++ ERP LS  ++ + L  MWN+
Sbjct: 221 TKKKFKDP---------NAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNN 271

Query: 448 LSEKKKAKYKAREAALKAQSER 469
            +   K  Y+ R A LK + E+
Sbjct: 272 TAADDKQPYEKRSAKLKEKYEK 293



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 42/165 (25%), Positives = 76/165 (46%), Gaps = 28/165 (16%)

Query: 429 RPELSESELTRLLARMWNDLSEKKKAKY-----------KAREAALKAQSER--KPGGER 475
           R  ++ SE ++  +  W ++S K+K K+           KA +A  K + +    P GE 
Sbjct: 162 RVSVNFSEFSKKCSERWKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGET 221

Query: 476 EERGKLPESPKRAEEIWQQSVIGDYLARFKNDRV-----KALKAMEMTWNNMEKKEKLMW 530
           +++ K P +PKR    +      +Y  + K +R         K +   WNN    +K  +
Sbjct: 222 KKKFKDPNAPKRPPSAFFL-YFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPY 280

Query: 531 IKKAAEDQKRYERELSEMRAP---PAATN------SSKKMKFQGE 566
            K++A+ +++YE++++  RA     AA N       SKK K + E
Sbjct: 281 EKRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEE 325



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 36/136 (26%), Positives = 58/136 (42%), Gaps = 14/136 (10%)

Query: 58  VAFKDFSGDMCKLKWVEIS-NEVRKFRTLTELILDAQEHVKNPYKG------------KK 104
           V F +FS   C  +W  +S  E  KF        D  +  K  YK             KK
Sbjct: 165 VNFSEFS-KKCSERWKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGETKK 223

Query: 105 LKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQD 164
             K P+ PK+P + +F +F E   K     P +S  D+ K L + +       K  Y + 
Sbjct: 224 KFKDPNAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKR 283

Query: 165 FQREKQEFERNLARFR 180
             + K+++E+++A +R
Sbjct: 284 SAKLKEKYEKDIAAYR 299



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 34/169 (20%), Positives = 79/169 (46%), Gaps = 18/169 (10%)

Query: 132 KLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDH-------- 183
           K+   ++  + +K  S+++K +  K+K K    F R + +FE ++A+  + H        
Sbjct: 160 KVRVSVNFSEFSKKCSERWKNMSAKEKGK----FGRARGKFE-DMAKADKAHYKREMKTY 214

Query: 184 -PDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKV---RPDATTKEVKDSLGKQWSQLSD 239
            P   +  KK   P  PK P   ++ +  +   K+   RP  +  +V   LG+ W+  + 
Sbjct: 215 IPPKGETKKKFKDPNAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAA 274

Query: 240 KKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQ 288
             +  +  ++ + +++YE+ +  Y  K    + +  G+ K+  +K +++
Sbjct: 275 DDKQPYEKRSAKLKEKYEKDIAAYRAKGKH-DAANNGVVKAAKSKKKKE 322



 Score = 33.1 bits (74), Expect = 0.99
 Identities = 38/191 (19%), Positives = 72/191 (37%), Gaps = 33/191 (17%)

Query: 216 KVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEE 275
           KVR      E      ++W  +S K++ K+  +A  + ++  +  + + ++  +  I  +
Sbjct: 160 KVRVSVNFSEFSKKCSERWKNMSAKEKGKF-GRARGKFEDMAKADKAHYKREMKTYIPPK 218

Query: 276 GITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLC------- 328
           G TK              D    K PP+++ LY +E    +K     ER  L        
Sbjct: 219 GETKKKFK----------DPNAPKRPPSAFFLYFSEYGPKIKG----ERPGLSFGDVAKK 264

Query: 329 -SQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA 387
             + W   +  +K  Y K+  + K+ YE ++  +          R  G+    N    +A
Sbjct: 265 LGEMWNNTAADDKQPYEKRSAKLKEKYEKDIAAY----------RAKGKHDAANNGVVKA 314

Query: 388 TSPASKKPAQE 398
                KK  +E
Sbjct: 315 AKSKKKKEEEE 325


>gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]
          Length = 879

 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 56/189 (29%), Positives = 86/189 (45%), Gaps = 28/189 (14%)

Query: 512 LKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPP 571
           LK    TW  +  KEK  +   A  D+  YERE+     P       KK K    PK+PP
Sbjct: 716 LKKCSETWKTIFAKEKGKFEDMAKADKAHYEREMKTYIPPKG--EKKKKFKDPNAPKRPP 773

Query: 572 MNGYQKFSQELLSN--GELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVH 629
           +  +  F  E      GE   L + + + ++   W   + + K+ Y+K A + +++YK  
Sbjct: 774 L-AFFLFCSEYRPKIKGEHPGLSIDDVVKKLAGMWNNTAAADKQFYEKKAAKLKEKYK-- 830

Query: 630 LDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDED 689
                     +D AAY+     K K       PN    R     KS+ ++++EEDE+DE 
Sbjct: 831 ----------KDIAAYRA----KGK-------PNSAKKRVVKAEKSKKKKEEEEDEEDEQ 869

Query: 690 EDEEEEDDE 698
           E+E EEDD+
Sbjct: 870 EEENEEDDD 878



 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 102/448 (22%), Positives = 168/448 (37%), Gaps = 102/448 (22%)

Query: 67  MCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEK 126
           MC  K V  S E R   +    ++D  +   N      L+KH                 K
Sbjct: 492 MCFPKGVPRSQEARTESSQASDMMDTMDVENN----STLEKHSG---------------K 532

Query: 127 RAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDL 186
           R K  +   +++ L   +   +  K L    K++  +  QR ++   R L R R+  P +
Sbjct: 533 RRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRI 592

Query: 187 IQ----NAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQ-WSQLSDKK 241
            +    N K+S++P                         T  EVK +L K+ + Q + KK
Sbjct: 593 PKDENINFKQSELP------------------------VTCGEVKGTLYKERFKQGTSKK 628

Query: 242 RLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPP 301
            ++   K     +E+E        K+ +L+I   G T   L      +++KF   P    
Sbjct: 629 CIQSEDKKWFTPREFEIEGDRGASKNWKLSIRCGGYTLKVL------MENKFLPEPPSTR 682

Query: 302 P--------NSYSLYCAELMANMKD--VPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKK 351
                    N+    C E      D  V  +E +  CS+ WK +  KEK  +       K
Sbjct: 683 KKRILESHNNTLVDPCEEHKKKNPDASVKFSEFLKKCSETWKTIFAKEKGKFEDMAKADK 742

Query: 352 KDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPV 411
             YE E+  ++    E+               KK+   P +              PKRP 
Sbjct: 743 AHYEREMKTYIPPKGEK---------------KKKFKDPNA--------------PKRPP 773

Query: 412 SAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSER-- 469
            A F+F  E R +++ E P LS  ++ + LA MWN+ +   K  Y+ + A LK + ++  
Sbjct: 774 LAFFLFCSEYRPKIKGEHPGLSIDDVVKKLAGMWNNTAAADKQFYEKKAAKLKEKYKKDI 833

Query: 470 -------KPGGEREERGKLPESPKRAEE 490
                  KP   ++   K  +S K+ EE
Sbjct: 834 AAYRAKGKPNSAKKRVVKAEKSKKKKEE 861



 Score = 33.9 bits (76), Expect = 0.58
 Identities = 27/166 (16%), Positives = 73/166 (43%), Gaps = 17/166 (10%)

Query: 595 ERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRK 654
           E + +    W+ I   +K  ++ +A+  +  Y+  +  ++     + +  +K+  + KR 
Sbjct: 714 EFLKKCSETWKTIFAKEKGKFEDMAKADKAHYEREMKTYIPPKG-EKKKKFKDPNAPKRP 772

Query: 655 SMT----------KLRGPNPKSSRTTLQSK------SESEEDDEEDEDDEDEDEEEEDDE 698
            +           K++G +P  S   +  K      + +  D +  E    + +E+   +
Sbjct: 773 PLAFFLFCSEYRPKIKGEHPGLSIDDVVKKLAGMWNNTAAADKQFYEKKAAKLKEKYKKD 832

Query: 699 NGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNE 744
                  G  +S      ++E   + +E++EDE+D+++++ +ED++
Sbjct: 833 IAAYRAKGKPNSAKKRVVKAEKSKKKKEEEEDEEDEQEEENEEDDD 878


>gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens]
          Length = 488

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 57/216 (26%), Positives = 102/216 (47%), Gaps = 44/216 (20%)

Query: 519 WNNMEKKEKLMWIKK-------AAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPP 571
           W NM  KEK  + +        A  D+  Y+RE+     P   T   KK K    PK+PP
Sbjct: 178 WKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGETK--KKFKDPNAPKRPP 235

Query: 572 MNGYQKFSQ-ELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHL 630
              +  FS+      GE   L   +   ++G  W   +   K+ Y+K + + +++Y+   
Sbjct: 236 SAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKRSAKLKEKYE--- 292

Query: 631 DLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQ-SKSESEEDDEEDEDDED 689
                    +D AAY            + +G +  ++   ++ +KS+ ++++EE+E+DE+
Sbjct: 293 ---------KDIAAY------------RAKGKHDAANNGVVKAAKSKKKKEEEENEEDEE 331

Query: 690 EDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE 725
           ++EEE+D+E+ D  +D         EDE EDGD+ +
Sbjct: 332 DEEEEKDEEDEDEEDD---------EDEEEDGDDEQ 358



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 22/142 (15%)

Query: 328 CSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA 387
           CS++WK +S KEK  + +   +             E + + ++     E K   I  K  
Sbjct: 174 CSERWKNMSAKEKGKFGRARGK------------FEDMAKADKAHYKREMKTY-IPPKGE 220

Query: 388 TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWND 447
           T    K P           PKRP SA F++  E   +++ ERP LS  ++ + L  MWN+
Sbjct: 221 TKKKFKDP---------NAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNN 271

Query: 448 LSEKKKAKYKAREAALKAQSER 469
            +   K  Y+ R A LK + E+
Sbjct: 272 TAADDKQPYEKRSAKLKEKYEK 293



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 33/183 (18%)

Query: 603 RWQRISQSQKEHYKKLA---EEQQKQYKVHLDLWVKSLSP---QDRAAYKEYISNKRKSM 656
           RW+ +S  +K  + +     E+  K  K H    +K+  P   + +  +K+  + KR   
Sbjct: 177 RWKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGETKKKFKDPNAPKRPPS 236

Query: 657 T----------KLRGPNPKSSRTTLQSK-----SESEEDDEEDEDDEDEDEEEEDDEN-- 699
                      K++G  P  S   +  K     + +  DD++  +      +E+ +++  
Sbjct: 237 AFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKRSAKLKEKYEKDIA 296

Query: 700 -------GDSSEDGG-DSSESSSEDESEDGDENEEDDEDEDDDEDDDE--DEDNESEGSS 749
                   D++ +G   +++S  + E E+ +E+EED+E+E D+ED+DE  DED E +G  
Sbjct: 297 AYRAKGKHDAANNGVVKAAKSKKKKEEEENEEDEEDEEEEKDEEDEDEEDDEDEEEDGDD 356

Query: 750 SSS 752
             S
Sbjct: 357 EQS 359



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 42/165 (25%), Positives = 76/165 (46%), Gaps = 28/165 (16%)

Query: 429 RPELSESELTRLLARMWNDLSEKKKAKY-----------KAREAALKAQSER--KPGGER 475
           R  ++ SE ++  +  W ++S K+K K+           KA +A  K + +    P GE 
Sbjct: 162 RVSVNFSEFSKKCSERWKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGET 221

Query: 476 EERGKLPESPKRAEEIWQQSVIGDYLARFKNDRV-----KALKAMEMTWNNMEKKEKLMW 530
           +++ K P +PKR    +      +Y  + K +R         K +   WNN    +K  +
Sbjct: 222 KKKFKDPNAPKRPPSAFFL-YFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPY 280

Query: 531 IKKAAEDQKRYERELSEMRAP---PAATN------SSKKMKFQGE 566
            K++A+ +++YE++++  RA     AA N       SKK K + E
Sbjct: 281 EKRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEE 325



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 36/136 (26%), Positives = 58/136 (42%), Gaps = 14/136 (10%)

Query: 58  VAFKDFSGDMCKLKWVEIS-NEVRKFRTLTELILDAQEHVKNPYKG------------KK 104
           V F +FS   C  +W  +S  E  KF        D  +  K  YK             KK
Sbjct: 165 VNFSEFS-KKCSERWKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGETKK 223

Query: 105 LKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQD 164
             K P+ PK+P + +F +F E   K     P +S  D+ K L + +       K  Y + 
Sbjct: 224 KFKDPNAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKR 283

Query: 165 FQREKQEFERNLARFR 180
             + K+++E+++A +R
Sbjct: 284 SAKLKEKYEKDIAAYR 299



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 34/169 (20%), Positives = 79/169 (46%), Gaps = 18/169 (10%)

Query: 132 KLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDH-------- 183
           K+   ++  + +K  S+++K +  K+K K    F R + +FE ++A+  + H        
Sbjct: 160 KVRVSVNFSEFSKKCSERWKNMSAKEKGK----FGRARGKFE-DMAKADKAHYKREMKTY 214

Query: 184 -PDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKV---RPDATTKEVKDSLGKQWSQLSD 239
            P   +  KK   P  PK P   ++ +  +   K+   RP  +  +V   LG+ W+  + 
Sbjct: 215 IPPKGETKKKFKDPNAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAA 274

Query: 240 KKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQ 288
             +  +  ++ + +++YE+ +  Y  K    + +  G+ K+  +K +++
Sbjct: 275 DDKQPYEKRSAKLKEKYEKDIAAYRAKGKH-DAANNGVVKAAKSKKKKE 322



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 44/229 (19%), Positives = 85/229 (37%), Gaps = 44/229 (19%)

Query: 216 KVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEE 275
           KVR      E      ++W  +S K++ K+  +A  + ++  +  + + ++  +  I  +
Sbjct: 160 KVRVSVNFSEFSKKCSERWKNMSAKEKGKF-GRARGKFEDMAKADKAHYKREMKTYIPPK 218

Query: 276 GITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLC------- 328
           G TK              D    K PP+++ LY +E    +K     ER  L        
Sbjct: 219 GETKKKFK----------DPNAPKRPPSAFFLYFSEYGPKIKG----ERPGLSFGDVAKK 264

Query: 329 -SQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA 387
             + W   +  +K  Y K+  + K+ YE ++  +          R  G+    N    +A
Sbjct: 265 LGEMWNNTAADDKQPYEKRSAKLKEKYEKDIAAY----------RAKGKHDAANNGVVKA 314

Query: 388 TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESE 436
                KK  +E  +   ++            EEK  + ++E  +  E E
Sbjct: 315 AKSKKKKEEEENEEDEEDE-----------EEEKDEEDEDEEDDEDEEE 352


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 114/611 (18%), Positives = 240/611 (39%), Gaps = 54/611 (8%)

Query: 154 PEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKV 213
           PE +K    Q  +  ++E E       +DH   I   +K+++         L+Y+ +   
Sbjct: 69  PEDEKKASHQHQEALRREIEA------QDHTIRILTCQKTELETA------LYYSQDAAR 116

Query: 214 YLKVRPDATTKEVKDSLGKQWSQLSDKKRL-----KWIHKALEQRKEYEEIMRDYIQKHP 268
             +      +K++   L   W    + +R       W HK  ++  E     RD +    
Sbjct: 117 KFEDGNLGESKDLAGRLHHSWHFAGELQRALSAVSTW-HKKADRYIEELTKERDALS--- 172

Query: 269 ELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKD----VPSTER 324
            L +    IT   L K   +L++K   R  +   +   L   EL   ++     +P  + 
Sbjct: 173 -LELYRNTITNEELKKKNAELQEKL--RLAESEKSEIQLNVKELKRKLERAKFLLPQVQT 229

Query: 325 MVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINK 384
             L  + W+   +  +     +  ++K   + E LR  E    E+++++  +EK L   +
Sbjct: 230 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQE 289

Query: 385 KQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARM 444
           K+      +   Q+  +   E+ +          +E++   QEE+    E ++ R   R+
Sbjct: 290 KELREQEKELREQKKLREQEEQMQE---------QEEKMWEQEEKMREQEEKMWRQEERL 340

Query: 445 WNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARF 504
           W    + ++ + K R+   +   + +   E+EER       +  E++W+Q        R 
Sbjct: 341 WEQEKQMREQEQKMRDQEERMWEQDERLREKEER------MREQEKMWEQEEKMQEEERI 394

Query: 505 KNDRVKALKAMEMTWNN----MEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKK 560
           + +R K ++  E T       M+K+E+ MW ++  E Q++   E  E           ++
Sbjct: 395 R-EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 453

Query: 561 MKFQGEPK---KPPMNGYQK--FSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHY 615
             ++ E K   +  M G +K  + QE +   E      +E+M +   +     +   E  
Sbjct: 454 KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQD 513

Query: 616 KKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKS 675
           ++L E++++  +    +W +    ++    +E          K+R       R     + 
Sbjct: 514 ERLREKEERM-REQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 572

Query: 676 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 735
           E    ++E++  E E++  E +E     E+     E    ++ E   E EE+D+ ++ +E
Sbjct: 573 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEE 632

Query: 736 DDDEDEDNESE 746
              E E+   E
Sbjct: 633 MMWEQEEKMQE 643



 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 118/618 (19%), Positives = 246/618 (39%), Gaps = 64/618 (10%)

Query: 156 KKKMKYIQDFQREKQ----EFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEK 211
           KK  +YI++  +E+     E  RN     E      +  +K  + E  K+  QL     K
Sbjct: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214

Query: 212 KVYLKVR---PDATTKEVKDSLGKQWSQLSD-----KKRLKWIHKALEQRKEYEEIMRDY 263
           +   + +   P   T  +++ + +Q  +L +     +K+ + + +  E+ +E E  MR+ 
Sbjct: 215 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ 274

Query: 264 IQK--HPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPS 321
            +K    E  + E+   +  L + E++L+++   R  +           E    M++   
Sbjct: 275 EEKMRRQEKRLREQ---EKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEE 331

Query: 322 T-----ERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVE-LLRFLESLPEEEQ----- 370
                 ER+    +Q +   QK +D   +  +Q ++  E E  +R  E + E+E+     
Sbjct: 332 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEE 391

Query: 371 QRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKP-----KRPVSAMFIFSEEKRRQL 425
           +R+   EK +   ++       K   QE      E+      + P     ++ +EK ++ 
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451

Query: 426 QEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESP 485
           +E+  E  + E  R    MW    EKK      R+  ++ Q ++    E + R +  +  
Sbjct: 452 EEKIWE--QEEKIRDQEEMWGQ--EKKMW----RQEKMREQEDQMWEQEEKMRDQEQKMW 503

Query: 486 KRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYEREL 545
            + E +W+Q    D   R K +R++  K M      M +++K    +K   DQ+   RE 
Sbjct: 504 DQEERMWEQ----DERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE 559

Query: 546 SEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSR-W 604
             MR         ++M  + E K        +  +E +   E      +E+M E   + W
Sbjct: 560 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 619

Query: 605 QRISQSQKEHYKKLA-EEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPN 663
           ++  + + +  +++  E+++K  +    +W      +     +E     R+   K++G  
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMW------EQEEKMREQEEKMREQEEKMQGQE 673

Query: 664 PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDE 723
            K             E +E+ +  E++  E+E+   G   +  G   +   ++E   G E
Sbjct: 674 EKM-----------REQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQE 722

Query: 724 NEEDDEDEDDDEDDDEDE 741
              + E+   D+ +   E
Sbjct: 723 EMREKEERIRDQKEKMQE 740



 Score = 66.6 bits (161), Expect = 8e-11
 Identities = 96/488 (19%), Positives = 201/488 (41%), Gaps = 24/488 (4%)

Query: 80  RKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSN 139
           R+ + L E   + +E  K   + KKL++  +  ++     +    + R +  K+  +   
Sbjct: 280 RQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 339

Query: 140 L-DLTKILSKKYKELPEKKKMKYIQDFQ-REKQEFERNLARFREDHPDLIQNAKKSDIPE 197
           L +  K + ++ +++ ++++  + QD + REK+E  R   +  E    + +  +  +  +
Sbjct: 340 LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREK 399

Query: 198 KPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQ--LSDKKRLKWIHKALEQRKE 255
           K +  ++     E+K+  +       + + +   K+W Q  L ++K   W  + +++++E
Sbjct: 400 KMREEEETMREQEEKMQKQ------EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 453

Query: 256 YEEIMRDYIQKHPELNISEEGITKSTLTKAER----QLKDKFDGRPTKPPPNSYSLYCAE 311
                 + I+   E+   E+ + +    + +     + ++K   +  K       ++  +
Sbjct: 454 KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQD 513

Query: 312 LMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKC-DQKKKDYEVELLRFLES-LPEEE 369
                K+    E+  +  Q+ K+  +K+     KK  DQ++K  E E +R  E  + EEE
Sbjct: 514 ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 573

Query: 370 QQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEER 429
           +     EEKM    +K           +E  +   EK       M+   EE + Q QEE 
Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633

Query: 430 PELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAE 489
               E ++     +MW    + ++ + K RE   K Q + +   E+EE+ +  E   R +
Sbjct: 634 MWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQ 693

Query: 490 EIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIK----KAAEDQKRYEREL 545
           E   + + G    +      K     E  W   E +EK   I+    K  E    +E   
Sbjct: 694 E---EKMRGQE-EKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERC 749

Query: 546 SEMRAPPA 553
           SE   PP+
Sbjct: 750 SEPCLPPS 757


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 34/92 (36%), Positives = 45/92 (48%)

Query: 673 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 732
           SKSES+  D + + D  +    +  +N DSS+    S+ S S D S+  D +   D    
Sbjct: 627 SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNS 686

Query: 733 DDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
            D  D  D  N SE S SS SS  DSSDS  +
Sbjct: 687 SDSSDSSDSSNSSESSDSSDSSDSDSSDSSDS 718



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 32/105 (30%), Positives = 51/105 (48%)

Query: 660 RGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESE 719
           +G +  S   +  S + S+  D  D D  D +   + D +   S D  DS  S S + S+
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD 603

Query: 720 DGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
             D ++  D  +  D  D + + ++SE  SS S S  DSSDS+S+
Sbjct: 604 SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648



 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 33/110 (30%), Positives = 57/110 (51%)

Query: 655 SMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSS 714
           S +K      +S  +   SKS+S + +  D  D  +  +  +  N   S D  DSS+SSS
Sbjct: 620 SDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS 679

Query: 715 EDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
             +S +  ++ +  +  +  E  D  + ++S+ S SS SS+ +SSDSDS+
Sbjct: 680 SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSS 729



 Score = 70.5 bits (171), Expect = 6e-12
 Identities = 34/115 (29%), Positives = 49/115 (42%)

Query: 650  SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
            SN   S       +   S  +  S   S+  D  D  D     +  D  +   S D  DS
Sbjct: 1139 SNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1198

Query: 710  SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
            S+SS   +S D  ++ +  +  D  +  D  + NES  SS SS SS  S+ SDS+
Sbjct: 1199 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSS 1253



 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 36/118 (30%), Positives = 56/118 (47%), Gaps = 3/118 (2%)

Query: 650 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEE---DEDDEDEDEEEEDDENGDSSEDG 706
           S K KS +     +  S+ +     S+S+  D     D D  D D  +  D +   S + 
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNS 601

Query: 707 GDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
            DSS+SS   +S D  ++ +   D    E D  D D++S+ S S+SS S D+SDS  +
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS 659



 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 34/117 (29%), Positives = 56/117 (47%), Gaps = 2/117 (1%)

Query: 650 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE--DGG 707
           SN   S       +  S+ ++    S+S+  D  D D  D     +  ++ DSS+  D  
Sbjct: 558 SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSS 617

Query: 708 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
           DSS+S S+    + D ++ D + +  D +  +  DN     SS+SS+S DSSDS  +
Sbjct: 618 DSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDS 674



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 36/119 (30%), Positives = 51/119 (42%), Gaps = 4/119 (3%)

Query: 650 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
           SN   S       N   S  +  S + S+  D  D  D  +     D  +  +S D  DS
Sbjct: 738 SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797

Query: 710 SESS----SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
           S SS    S D S+  D ++ D  +  D  +  +  D+ +   SS SS S D SDSDS+
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS 856



 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 36/104 (34%), Positives = 48/104 (46%), Gaps = 5/104 (4%)

Query: 666 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS----SEDESEDG 721
           SS +       S   D  D  +  +  +  D  N   S D  DSS SS    S D S+  
Sbjct: 718 SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777

Query: 722 DENEEDDEDEDDDEDDDEDEDNESEGSSSSSSS-SGDSSDSDSN 764
           D +   D ++  +  D  D  N S+ S+SS SS S DSSDSDS+
Sbjct: 778 DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 37/117 (31%), Positives = 51/117 (43%), Gaps = 2/117 (1%)

Query: 650  SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
            SN   S       +   S  +  S   S+  D  +  D  +  +  D  +   S D  DS
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081

Query: 710  SESS-SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSS-SSSSGDSSDSDSN 764
            SESS S D S   D ++  D  +  D  D  D  + S+ S+SS SS S DSSDS  +
Sbjct: 1082 SESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1138



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 1/115 (0%)

Query: 650  SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
            SN   S       +   S  +  S   SE  D  D  D  +  +  D  +   S D  +S
Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1180

Query: 710  SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
            S+SS   +S D  ++  D  D  D  D  +  D+     SS SS S DSSDS+ +
Sbjct: 1181 SDSSDSSDSSDSSDSS-DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNES 1234



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 33/117 (28%), Positives = 50/117 (42%), Gaps = 2/117 (1%)

Query: 650  SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
            S+   S       +   S  +  S   S+  D  D  D  +  +  D  +   S D  DS
Sbjct: 1172 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1231

Query: 710  SESSSEDESEDGDE--NEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
            +ESS   +S D  +  N  D  D  D  D   D ++ES+  S S + + + SDSDS+
Sbjct: 1232 NESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSD 1288



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 1/100 (1%)

Query: 666 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE 725
           S+  T  S S    ++  D++D+ +  + + D +   S D  +SS+SS   +S+  D N 
Sbjct: 517 STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS 576

Query: 726 EDDEDEDD-DEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
             D D  D D  D  D D+    +SS SS S DSSDS  +
Sbjct: 577 SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS 616



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 38/127 (29%), Positives = 52/127 (40%), Gaps = 12/127 (9%)

Query: 650 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE--DGG 707
           SN   S       +   S  +  S + S+  D  D  D D     +   + DSS+  +  
Sbjct: 780 SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839

Query: 708 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSS----------SSSSGD 757
           DSS+SS   +  D D +   D     D  D  D  N S+ S SS          SS S +
Sbjct: 840 DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSN 899

Query: 758 SSDSDSN 764
           SSDSDS+
Sbjct: 900 SSDSDSS 906



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 32/115 (27%), Positives = 47/115 (40%)

Query: 650 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
           SN   S       +  +S  +  S   S+  D     D     +  D  +  +S +  DS
Sbjct: 645 SNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS 704

Query: 710 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
           S+SS  D S+  D +  +  D D     D  + + S  SS SS SS  S  SDS+
Sbjct: 705 SDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 759



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 37/117 (31%), Positives = 48/117 (41%), Gaps = 2/117 (1%)

Query: 650 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
           SN   S       +   S  +  S   S+  D  +  D  +  +  D  +  +S D  DS
Sbjct: 729 SNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDS 788

Query: 710 SESS-SEDESEDGD-ENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
           S SS S D S   D  N  D  D  D  D D    ++S  SS SS SS  S  SDS+
Sbjct: 789 SNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 34/118 (28%), Positives = 49/118 (41%), Gaps = 3/118 (2%)

Query: 650 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGD---SSEDG 706
           SN   S       N   S  +  S   S+  +  D +D     +  D  N     +S D 
Sbjct: 750 SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS 809

Query: 707 GDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
            DSS+SS  D S   D +   D  +  +  D  D  + S+GS S SS+  DSS+S  +
Sbjct: 810 SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 36/116 (31%), Positives = 51/116 (43%), Gaps = 3/116 (2%)

Query: 650  SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
            S+   S       +   S  +  S   S+  D  +  D  +  +  D  +  +S D  DS
Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDS 1147

Query: 710  SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGS-SSSSSSSGDSSDSDSN 764
            SESS  D S+  D ++  D  +  D  D  D  N S+ S SS SS S DSSDS  +
Sbjct: 1148 SESS--DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1201



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 32/99 (32%), Positives = 44/99 (44%), Gaps = 1/99 (1%)

Query: 667 SRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS-SEDESEDGDENE 725
           S  +  S   S   D  D  D     +  D  +  +S D  DSS+SS S D S   D N+
Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND 787

Query: 726 EDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
             +  +  D  +  D  N S+ S SS SS  DSS+S  +
Sbjct: 788 SSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDS 826



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 31/115 (26%), Positives = 49/115 (42%)

Query: 650 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
           S+   S       +   S  + +S + S+  D  +  D D  +     ++ DSS     S
Sbjct: 865 SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS 924

Query: 710 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
             S+S D S   D +   D  +  D  +  D  N S+ S+SS SS  +SSDS  +
Sbjct: 925 ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDS 979



 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 1/89 (1%)

Query: 677 SEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDED 736
           ++++D+ D      D  + D  +  +S D  DSS+S S D +   D +  D +  D  + 
Sbjct: 534 NDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDS 593

Query: 737 DDEDEDNESEGSSSSSSS-SGDSSDSDSN 764
           D  D  N S+ S SS SS S DSSDS  +
Sbjct: 594 DSSDSSNSSDSSDSSDSSDSSDSSDSSDS 622



 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 27/90 (30%), Positives = 43/90 (47%)

Query: 675 SESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDD 734
           S+S+  +  D  +  +  +  D  N   S D  DS+ESS+  +S D   + + D  +  +
Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 910

Query: 735 EDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
             D  D  N S+ S SS+SS   +S   SN
Sbjct: 911 SSDSSDSSNSSDSSESSNSSDNSNSSDSSN 940



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 54/245 (22%), Positives = 99/245 (40%), Gaps = 24/245 (9%)

Query: 537 DQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGE--------- 587
           + KR E  +++     + T++  K + +G   K P +G +  ++E+    E         
Sbjct: 351 ESKRVENRITK----ESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHG 406

Query: 588 ----LNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRA 643
                 ++  +  +V I    Q+     K  +     +         D   KS+   D  
Sbjct: 407 MILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPN 466

Query: 644 AYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDD---EDEDEEE-EDDEN 699
           +  E   N   +       N  SSR      S+  +D+    D    ED+D +   D  N
Sbjct: 467 SSDESNGNDDANS---ESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNN 523

Query: 700 GDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSS 759
            DS+ +G + ++ + + +S  G  +  D +  D     D  + ++S+ S S+SSS  DSS
Sbjct: 524 SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSS 583

Query: 760 DSDSN 764
           DSDS+
Sbjct: 584 DSDSS 588



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 36/114 (31%), Positives = 50/114 (43%), Gaps = 15/114 (13%)

Query: 666 SSRTTLQSKSESEEDDEEDEDDE--DEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDE 723
           +S  +  S   S+  D  D  D   D  + E D  + DS  D  DS+ S S D S+  D 
Sbjct: 600 NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS 659

Query: 724 NEEDDEDEDDDEDDDEDEDNESEGSSSS-------------SSSSGDSSDSDSN 764
           +   +  +  D  D  D  + S+ S+SS             SS S DSSDSDS+
Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS 713



 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 31/115 (26%), Positives = 46/115 (40%)

Query: 650 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
           SN   S       +   S  +  S   S   D  D  +  +     D  +   S D   S
Sbjct: 762 SNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821

Query: 710 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
           + S S + S+  D +   D  +  D  D  D D+ +   SS+SS S DSSDS ++
Sbjct: 822 NSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876



 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 28/102 (27%), Positives = 46/102 (45%)

Query: 663 NPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGD 722
           N   S  +  S   S+  D  D  D D     +   + DSS+    S+ S S D S+  +
Sbjct: 828 NSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNE 887

Query: 723 ENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
            +   D  +  +  D +  D+ +   SS SS+S DSS+S ++
Sbjct: 888 SSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 1/115 (0%)

Query: 650 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
           S+   S +     +  S   +  S      D     D  D  +  +  ++ DSS+   DS
Sbjct: 567 SDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDS 626

Query: 710 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
           S+S S D S+   +++  D +  D  D+ +  D+ +  +SS SS S DSSDS S+
Sbjct: 627 SKSES-DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS 680



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 31/100 (31%), Positives = 48/100 (48%), Gaps = 1/100 (1%)

Query: 666 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE-DGGDSSESSSEDESEDGDEN 724
           SS ++  S S    +  +  D  D     E  ++ DSS+ D  DSS+SS+ + S+    N
Sbjct: 671 SSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSN 730

Query: 725 EEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
             D  D  +  D  +  D+ +   SS SS S +SSDS  +
Sbjct: 731 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 34/120 (28%), Positives = 52/120 (43%), Gaps = 5/120 (4%)

Query: 650 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGG-- 707
           S+   S +     N   S  +  S + SE  D  D  D D  +  +   +  S  D    
Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS 731

Query: 708 -DSSESSSEDESEDGDE--NEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
            DSS+SS+  +S D  +  N  D  D  D  +  +  D+     SS SS+S DS+DS ++
Sbjct: 732 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNS 791



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 29/102 (28%), Positives = 49/102 (48%)

Query: 663 NPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGD 722
           N   S+      S+S  D    + + + +   +D++  DS +   DSS+S S D S   D
Sbjct: 503 NGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSD 562

Query: 723 ENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
            ++  D D  D     + + ++S+ S SS S S DSS+S  +
Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDS 604



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 7/122 (5%)

Query: 650 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
           SN           +  SS +     S S +  +  +  +  D  +  D   DSS+   DS
Sbjct: 574 SNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDS 633

Query: 710 SESSSEDESEDGDENEEDDEDEDDD-------EDDDEDEDNESEGSSSSSSSSGDSSDSD 762
           S+S S+ +S D + ++  D  +  D        D  +  D+    SSS SS+S DSSDS 
Sbjct: 634 SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693

Query: 763 SN 764
            +
Sbjct: 694 DS 695



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 31/115 (26%), Positives = 50/115 (43%)

Query: 650  SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
            SN   S +     +  SS ++  S S    +  ++ +  D     +  ++ DSS     S
Sbjct: 898  SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957

Query: 710  SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
            + S S + S+  D N  D  D  +  D  +  D+     SS SS+S DSSDS  +
Sbjct: 958  NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1012



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 33/128 (25%), Positives = 61/128 (47%), Gaps = 1/128 (0%)

Query: 638 SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDD 697
           S +  A+Y    S    + +  +G     S +T  + +     +  + +D+++  +    
Sbjct: 486 SSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKG 545

Query: 698 ENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSS-SG 756
           ++  S  D  DSS SS   +S D D ++ +   + D  D D  + ++S+ S SS+SS S 
Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSS 605

Query: 757 DSSDSDSN 764
           DSSDS  +
Sbjct: 606 DSSDSSDS 613



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 34/101 (33%), Positives = 44/101 (43%), Gaps = 12/101 (11%)

Query: 674 KSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDD 733
           KS+S +   +  D +  D     D +  S  D  DS+ SS  D S D D ++  D D  D
Sbjct: 539 KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSD-SSDSDSSDSSDSDSSD 597

Query: 734 -----------DEDDDEDEDNESEGSSSSSSSSGDSSDSDS 763
                      D  D  D  + S+  S SS S  DSSDSDS
Sbjct: 598 SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS 638



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 2/116 (1%)

Query: 650 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
           S+   S     G +  SS  +  S S    D  +  +  D  +  + +E+ +SS D  DS
Sbjct: 839 SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS-DSSDS 897

Query: 710 SESSSEDESEDGDENEEDDEDEDDDEDDDEDE-DNESEGSSSSSSSSGDSSDSDSN 764
           S SS  D S+  + ++  D     D  +  +  DN +   SS+SS S DSSDS ++
Sbjct: 898 SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 33/101 (32%), Positives = 51/101 (50%), Gaps = 9/101 (8%)

Query: 666  SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE--DGGDSSESSSEDESEDGDE 723
            SS ++  S S    D  +  D  D  +  + +E+ DSS+  D  DSS SS   +S D  +
Sbjct: 1201 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSD 1260

Query: 724  NEEDDEDEDDDE-------DDDEDEDNESEGSSSSSSSSGD 757
            +  D  DE D +       ++  D D++SEGS S+ S+S D
Sbjct: 1261 STSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 35/118 (29%), Positives = 52/118 (44%), Gaps = 3/118 (2%)

Query: 650  SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
            SN   S       +   S  +  S   S+  D  D  D  +  +  D  +   S +  DS
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237

Query: 710  SESS-SEDESEDGDENE-EDDEDEDDDEDDDEDEDNES-EGSSSSSSSSGDSSDSDSN 764
            S+SS S D S   D ++  D  D   D +D+ D  ++S  G+++ S S  DS  SDSN
Sbjct: 1238 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSN 1295



 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 1/116 (0%)

Query: 650 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
           S+   S       +  +S  +  S   S+  D  +  D ++     D  +  +S D  +S
Sbjct: 747 SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNS 806

Query: 710 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSD-SDSN 764
           S+SS   +S D D +   D     D  D  +  + S+ S SS  S  DSS+ SDS+
Sbjct: 807 SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSS 862



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 11/126 (8%)

Query: 650 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
           S+ +   +     +   +  +  S + S   D  D  D  +     D  N   S D  DS
Sbjct: 636 SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS 695

Query: 710 SESSSEDESEDGDENEEDDEDE-------DDDEDDDEDEDNESEGSSSS----SSSSGDS 758
           S SS   +S D  +++  D  +       D D  +  D  + S  S SS    SS+S DS
Sbjct: 696 SNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDS 755

Query: 759 SDSDSN 764
           SDS  +
Sbjct: 756 SDSSDS 761



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 29/129 (22%), Positives = 54/129 (41%)

Query: 636 SLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEE 695
           S S  D +   +   +   S +     +  SS +     S+S   +  D D  +  +  +
Sbjct: 677 SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736

Query: 696 DDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 755
              + DSS+    S+ S S D S+  + ++  D  +  D  D  +  + ++ S+SS SS 
Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSD 796

Query: 756 GDSSDSDSN 764
             +S   SN
Sbjct: 797 SSNSSDSSN 805



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 23/92 (25%), Positives = 41/92 (44%)

Query: 673 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 732
           S S +  D++EDE   D+++EE  +    S+   G   +   +++  D    +  D  E 
Sbjct: 245 SPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEY 304

Query: 733 DDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
            D +  ED  NE +G  +S S    +   + N
Sbjct: 305 YDPEGKEDPHNEVDGDKTSKSEENSAGIPEDN 336



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 28/121 (23%), Positives = 50/121 (41%), Gaps = 10/121 (8%)

Query: 651 NKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDE----------DEEEEDDENG 700
           N+  ++ +  GP    S  +  ++ E  E+   +E +  E            +E +   G
Sbjct: 173 NEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPG 232

Query: 701 DSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSD 760
              + G D+S+ S      D DE+E   +DED++  + +D  N S+G         D  D
Sbjct: 233 TGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHD 292

Query: 761 S 761
           S
Sbjct: 293 S 293



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 19/79 (24%), Positives = 30/79 (37%)

Query: 650  SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
            S+   S       +   S  +  S + S+  D  D  D   D  +E D    S     + 
Sbjct: 1223 SDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNG 1282

Query: 710  SESSSEDESEDGDENEEDD 728
            S+S S+ E  D + +  DD
Sbjct: 1283 SDSDSDSEGSDSNHSTSDD 1301



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 25/96 (26%), Positives = 38/96 (39%), Gaps = 4/96 (4%)

Query: 666 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE 725
           +S  T Q  S+     E +      ++   D+ +G  S +G D      EDE    DE+E
Sbjct: 210 TSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGAD----EDEDEGSGDDEDE 265

Query: 726 EDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDS 761
           E    +D   +    E  +        SS G +SDS
Sbjct: 266 EAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDS 301


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 40/108 (37%), Positives = 64/108 (59%), Gaps = 3/108 (2%)

Query: 642 RAAYKEYISNKRKSMTKL-RGPNPKSSRTTLQSKSES--EEDDEEDEDDEDEDEEEEDDE 698
           R+ Y   ++ KRK+  K  + P PK     +++ S S  E DD +  +D DE EE+E +E
Sbjct: 50  RSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE 109

Query: 699 NGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 746
             + +++ GD  E   E + E+ +E EE+DED+D+D +D EDE+ E E
Sbjct: 110 YSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEE 157



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 30/94 (31%), Positives = 60/94 (63%), Gaps = 3/94 (3%)

Query: 671 LQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED 730
           +  K E E ++  +++DE  DE+EED+E GD  E+  +  E   ED+ EDG++ E+++E+
Sbjct: 99  MDEKEEDEGEEYSEDNDEPGDEDEEDEE-GDREEE--EEIEEEDEDDDEDGEDVEDEEEE 155

Query: 731 EDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
           E+++E+++E+E+NE    +  ++     ++ D N
Sbjct: 156 EEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDN 189



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 40/126 (31%), Positives = 62/126 (49%), Gaps = 41/126 (32%)

Query: 678 EEDDEEDEDDEDEDEE-EEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED------ 730
           +ED+E++E D +E+EE EE+DE  D  EDG D  +   E+E E+ +E EE++ED      
Sbjct: 119 DEDEEDEEGDREEEEEIEEEDE--DDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCH 176

Query: 731 --------EDDDEDDDEDED------------------------NESEGSSSSSSSSGDS 758
                   E DD ++DE ++                         ESE +S++S+S  D 
Sbjct: 177 NTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDD 236

Query: 759 SDSDSN 764
           SD + N
Sbjct: 237 SDKNEN 242


>gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens]
          Length = 487

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 54/202 (26%), Positives = 91/202 (45%), Gaps = 29/202 (14%)

Query: 519 WNNMEKKEKLMWIKK-------AAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPP 571
           W NM  KEK  + +        A  D+  Y+RE+     P   T   KK K    PK+PP
Sbjct: 178 WKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGETK--KKFKDPNAPKRPP 235

Query: 572 MNGYQKFSQELLS-NGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHL 630
              +  FS+      GE   L   +   ++G  W   +   K+ Y+K + + +++Y+   
Sbjct: 236 SAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKRSAKLKEKYE--- 292

Query: 631 DLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDE 690
                    +D AAY+    +   +   ++    K        K E EE++E++ED+E+E
Sbjct: 293 ---------KDIAAYRAKGKHDAANNGVVKAAKSKK-------KKEEEENEEDEEDEEEE 336

Query: 691 DEEEEDDENGDSSEDGGDSSES 712
            +EE++DE  D  E+ GD  +S
Sbjct: 337 KDEEDEDEEDDEDEEDGDDEQS 358



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 22/142 (15%)

Query: 328 CSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA 387
           CS++WK +S KEK  + +   +             E + + ++     E K   I  K  
Sbjct: 174 CSERWKNMSAKEKGKFGRARGK------------FEDMAKADKAHYKREMKTY-IPPKGE 220

Query: 388 TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWND 447
           T    K P           PKRP SA F++  E   +++ ERP LS  ++ + L  MWN+
Sbjct: 221 TKKKFKDP---------NAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNN 271

Query: 448 LSEKKKAKYKAREAALKAQSER 469
            +   K  Y+ R A LK + E+
Sbjct: 272 TAADDKQPYEKRSAKLKEKYEK 293



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 40/182 (21%), Positives = 83/182 (45%), Gaps = 31/182 (17%)

Query: 603 RWQRISQSQKEHYKKLA---EEQQKQYKVHLDLWVKSLSP---QDRAAYKEYISNKRKSM 656
           RW+ +S  +K  + +     E+  K  K H    +K+  P   + +  +K+  + KR   
Sbjct: 177 RWKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGETKKKFKDPNAPKRPPS 236

Query: 657 T----------KLRGPNPKSSRTTLQSK-----SESEEDDEEDEDDEDEDEEEEDDEN-- 699
                      K++G  P  S   +  K     + +  DD++  +      +E+ +++  
Sbjct: 237 AFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKRSAKLKEKYEKDIA 296

Query: 700 -------GDSSEDGG-DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSS 751
                   D++ +G   +++S  + E E+ +E+EED+E+E D+ED+DE++D + E     
Sbjct: 297 AYRAKGKHDAANNGVVKAAKSKKKKEEEENEEDEEDEEEEKDEEDEDEEDDEDEEDGDDE 356

Query: 752 SS 753
            S
Sbjct: 357 QS 358



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 42/165 (25%), Positives = 76/165 (46%), Gaps = 28/165 (16%)

Query: 429 RPELSESELTRLLARMWNDLSEKKKAKY-----------KAREAALKAQSER--KPGGER 475
           R  ++ SE ++  +  W ++S K+K K+           KA +A  K + +    P GE 
Sbjct: 162 RVSVNFSEFSKKCSERWKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGET 221

Query: 476 EERGKLPESPKRAEEIWQQSVIGDYLARFKNDRV-----KALKAMEMTWNNMEKKEKLMW 530
           +++ K P +PKR    +      +Y  + K +R         K +   WNN    +K  +
Sbjct: 222 KKKFKDPNAPKRPPSAFFL-YFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPY 280

Query: 531 IKKAAEDQKRYERELSEMRAP---PAATN------SSKKMKFQGE 566
            K++A+ +++YE++++  RA     AA N       SKK K + E
Sbjct: 281 EKRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEE 325



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 36/136 (26%), Positives = 58/136 (42%), Gaps = 14/136 (10%)

Query: 58  VAFKDFSGDMCKLKWVEIS-NEVRKFRTLTELILDAQEHVKNPYKG------------KK 104
           V F +FS   C  +W  +S  E  KF        D  +  K  YK             KK
Sbjct: 165 VNFSEFS-KKCSERWKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGETKK 223

Query: 105 LKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQD 164
             K P+ PK+P + +F +F E   K     P +S  D+ K L + +       K  Y + 
Sbjct: 224 KFKDPNAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKR 283

Query: 165 FQREKQEFERNLARFR 180
             + K+++E+++A +R
Sbjct: 284 SAKLKEKYEKDIAAYR 299



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 34/169 (20%), Positives = 79/169 (46%), Gaps = 18/169 (10%)

Query: 132 KLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDH-------- 183
           K+   ++  + +K  S+++K +  K+K K    F R + +FE ++A+  + H        
Sbjct: 160 KVRVSVNFSEFSKKCSERWKNMSAKEKGK----FGRARGKFE-DMAKADKAHYKREMKTY 214

Query: 184 -PDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKV---RPDATTKEVKDSLGKQWSQLSD 239
            P   +  KK   P  PK P   ++ +  +   K+   RP  +  +V   LG+ W+  + 
Sbjct: 215 IPPKGETKKKFKDPNAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAA 274

Query: 240 KKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQ 288
             +  +  ++ + +++YE+ +  Y  K    + +  G+ K+  +K +++
Sbjct: 275 DDKQPYEKRSAKLKEKYEKDIAAYRAKGKH-DAANNGVVKAAKSKKKKE 322



 Score = 33.9 bits (76), Expect = 0.58
 Identities = 45/229 (19%), Positives = 82/229 (35%), Gaps = 52/229 (22%)

Query: 216 KVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEE 275
           KVR      E      ++W  +S K++ K+  +A  + ++  +  + + ++  +  I  +
Sbjct: 160 KVRVSVNFSEFSKKCSERWKNMSAKEKGKF-GRARGKFEDMAKADKAHYKREMKTYIPPK 218

Query: 276 GITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLC------- 328
           G TK              D    K PP+++ LY +E    +K     ER  L        
Sbjct: 219 GETKKKFK----------DPNAPKRPPSAFFLYFSEYGPKIKG----ERPGLSFGDVAKK 264

Query: 329 -SQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA 387
             + W   +  +K  Y K+  + K+ YE ++  +          R  G+    N    +A
Sbjct: 265 LGEMWNNTAADDKQPYEKRSAKLKEKYEKDIAAY----------RAKGKHDAANNGVVKA 314

Query: 388 TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESE 436
                KK  +E                   +EE     +EE+ E  E E
Sbjct: 315 AKSKKKKEEEE-------------------NEEDEEDEEEEKDEEDEDE 344


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 74.3 bits (181), Expect = 4e-13
 Identities = 111/482 (23%), Positives = 202/482 (41%), Gaps = 111/482 (23%)

Query: 310  AELMANMKDVPSTERMVLCSQQWKLL--SQKEKDAYHKKCDQKKKDYEVELLRFLESLPE 367
            A++ +  K + S E   +  ++ +LL  S++  +   ++ D+++++ E E     E   E
Sbjct: 1037 AKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEE-----EEEDE 1091

Query: 368  EEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEE---KRRQ 424
            EE++    EE+  NI   Q++ P   KP     +  + K KRP    F+  ++   KRR+
Sbjct: 1092 EEEEEEEEEEEEENI---QSSPPRLTKP-----QSVAIKRKRP----FVLKKKRGRKRRR 1139

Query: 425  LQEERPELSESELTRLLARMWNDLSEKK-----------KAKYKAREAALKAQSERKPGG 473
            +       + SE T +L   +++  E++           + +   R+  L+   + +PG 
Sbjct: 1140 INSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGK 1199

Query: 474  ER---EERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEK-KEKLM 529
            +R   EE GK     K A          D      ND    LK  E + +N E  K K +
Sbjct: 1200 KRQTEEEEGKDNHCFKNA----------DPCRNNMNDDSSNLK--EGSKDNPEPLKCKQV 1247

Query: 530  WIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGE---PKKPPMNGYQKFS---QELL 583
            W K         +R LS+ R      N  +K  F+     P + PM   ++ +   Q+  
Sbjct: 1248 WPKGT-------KRGLSKWRQ-----NKERKTGFKLNLYTPPETPMEPDEQVTVEEQKET 1295

Query: 584  SNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRA 643
            S G+ +  P+            RI +  KE  + L  +++                    
Sbjct: 1296 SEGKTSPSPI------------RIEEEVKETGEALLPQEE-------------------- 1323

Query: 644  AYKEYISNKRKSMTKLRGPNPKSSRTTLQS--KSESEEDDEEDEDDEDEDEEEEDDENGD 701
                   N+R+       PN            K E EE++EE+E++E+E+EE E++E G 
Sbjct: 1324 -------NRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGG 1376

Query: 702  SSEDGGDSSESSSEDESEDGDENEED---DEDEDDDEDDDEDEDNESEGSSSSSSSSGDS 758
            + E   D ++S  ++E E   E E+    D+ E+++E+D+E   NE   +     S  +S
Sbjct: 1377 NVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMES 1436

Query: 759  SD 760
            ++
Sbjct: 1437 AE 1438



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 124/596 (20%), Positives = 214/596 (35%), Gaps = 119/596 (19%)

Query: 231  GKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKST--------L 282
            G     LSD  RL ++         ++ ++ +Y+  H E +IS + I+++T         
Sbjct: 888  GSPEKPLSDLGRLSYL-------AYWKSVILEYLYHHHERHISIKAISRATGMCPHDIAT 940

Query: 283  TKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWK--LLSQKEK 340
            T     + DK DGR          L     M  +K       +   S +W   L+S    
Sbjct: 941  TLQHLHMIDKRDGRFVIIRREKLIL---SHMEKLKTCSRANELDPDSLRWTPILISNAAV 997

Query: 341  DAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGG 400
                   ++++ + E E L    S  E+E+Q +L           +A S  S    Q   
Sbjct: 998  SE-----EEREAEKEAERLMEQASCWEKEEQEILST---------RANSRQSPAKVQSKN 1043

Query: 401  KGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKARE 460
            K       RPV+        +R QL E   E SE E             E+ + + +  E
Sbjct: 1044 KYLHSPESRPVTG-------ERGQLLELSKESSEEEE-----------EEEDEEEEEEEE 1085

Query: 461  AALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVI----GDYLARFKNDRVKALKAME 516
               + + E +   E EE   +  SP R  +   QSV       ++ + K  R +      
Sbjct: 1086 EEEEDEEEEEEEEEEEEEENIQSSPPRLTK--PQSVAIKRKRPFVLKKKRGRKRRRINSS 1143

Query: 517  MTWNNMEKKEKLMWIKKAAEDQKRYERELS---EMRAPPAATNSSKKMKFQGEPKK---- 569
            +T   + +  +++       D++R   +L    E+           +  FQ +P K    
Sbjct: 1144 VTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQT 1203

Query: 570  ---------------PPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEH 614
                           P  N     S  L    + N  PLK + V     W +     K  
Sbjct: 1204 EEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQV-----WPK---GTKRG 1255

Query: 615  YKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNP-------KSS 667
              K  + ++++    L+L+    +P +          K  S  K   P+P       K +
Sbjct: 1256 LSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKT-SPSPIRIEEEVKET 1314

Query: 668  RTTLQSKSESEEDD------------EEDEDD----EDEDEEEEDDENGDSSEDGGDSSE 711
               L  + E+  ++            E+ EDD    E+E+EEEE++E  +  E+G +   
Sbjct: 1315 GEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEG 1374

Query: 712  SSSEDESEDGDENEEDDEDEDDDE-------DDDEDEDNESEGSSSSSSSSGDSSD 760
              + ++  DG +++E +E E   E       DD E+E+ E E  S +     D  D
Sbjct: 1375 GGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDED 1430



 Score = 37.7 bits (86), Expect = 0.040
 Identities = 30/139 (21%), Positives = 62/139 (44%), Gaps = 29/139 (20%)

Query: 652  KRKSMTKLRGPNPKSSRTT---LQSKSESEEDDEEDEDDED--------EDEEEEDDENG 700
            K K+ ++    +P S R T   + + + SEE+ E +++ E         E EE+E     
Sbjct: 970  KLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTR 1029

Query: 701  DSSEDGGDSSESSSE------------------DESEDGDENEEDDEDEDDDEDDDEDED 742
             +S       +S ++                  + S++  E EE++EDE+++E+++E+E+
Sbjct: 1030 ANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEE 1089

Query: 743  NESEGSSSSSSSSGDSSDS 761
            +E E          ++  S
Sbjct: 1090 DEEEEEEEEEEEEEENIQS 1108



 Score = 31.6 bits (70), Expect = 2.9
 Identities = 110/611 (18%), Positives = 219/611 (35%), Gaps = 121/611 (19%)

Query: 146  LSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQL 205
            LSK+  E  E+++ +  ++ + E++E E       E+  +  +N + S  P +   PQ +
Sbjct: 1064 LSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE--ENIQSS--PPRLTKPQSV 1119

Query: 206  WYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQ 265
                ++   LK +     + +  S+  +         +    + L +  +  +  R   Q
Sbjct: 1120 AIKRKRPFVLKKKRGRKRRRINSSVTTE--------TISETTEVLNEPFDNSDEERPMPQ 1171

Query: 266  KHP--ELNISEEGITKSTLTKA------------ERQLKDKFDGRPTKPPPNSYSLYCAE 311
              P  E+ + E+G  K  L KA            E + KD    +   P  N+ +   + 
Sbjct: 1172 LEPTCEIEVEEDG-RKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSN 1230

Query: 312  LMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQ 371
            L    KD P   +   C Q W   +++    + +   ++K  +++ L    E+  E ++Q
Sbjct: 1231 LKEGSKDNPEPLK---CKQVWPKGTKRGLSKWRQN-KERKTGFKLNLYTPPETPMEPDEQ 1286

Query: 372  RVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPE 431
              + E+K  +  K   TSP+  +  +E  + G            +  +E+ R+ +   P 
Sbjct: 1287 VTVEEQKETSEGK---TSPSPIRIEEEVKETGEA----------LLPQEENRREETCAP- 1332

Query: 432  LSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEI 491
                            +S       K  +  +K + E +   E EE     E  +  EE 
Sbjct: 1333 ----------------VSPNTSPGEKPEDDLIKPEEEEEEEEEEEEE----EEEEEGEE- 1371

Query: 492  WQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAP 551
                                    E    N+EK          A+ Q++ E E+S  +  
Sbjct: 1372 ------------------------EEGGGNVEKDPD------GAKSQEKEEPEISTEKED 1401

Query: 552  PAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQ 611
             A  +  ++   + E ++P  N       E  S+ E   +  +E                
Sbjct: 1402 SARLDDHEEE--EEEDEEPSHNEDHDADDEDDSHMESAEVEKEEL--------------P 1445

Query: 612  KEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTL 671
            +E +K++ E Q+      LDL V     Q   +  E + +    +T      PK      
Sbjct: 1446 RESFKEVLENQE----TFLDLNV-----QPGHSNPEVLMDCGVDLTASCNSEPKELAGDP 1496

Query: 672  QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 731
            ++  ES+E+    E  + +D++   + + +  E    + E  SE         +E  E +
Sbjct: 1497 EAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQD 1556

Query: 732  DDDEDDDEDED 742
            D  +D  E ++
Sbjct: 1557 DTFQDCAETQE 1567


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 74.3 bits (181), Expect = 4e-13
 Identities = 80/379 (21%), Positives = 153/379 (40%), Gaps = 35/379 (9%)

Query: 403 GSEKPKRPVSAMF-IFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREA 461
           G EK    V  +  I  E+KRR+ QEE+     +E+ RL      D       + + R+ 
Sbjct: 2   GDEKDSWKVKTLDEILQEKKRRKEQEEK-----AEIKRLKNSDDRDSKRDSLEEGELRDH 56

Query: 462 ALKAQSERKP---GGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMT 518
            ++      P       E+RG+  E    A +  QQ    + +   K+++ K  K   + 
Sbjct: 57  CMEITIRNSPYRREDSMEDRGE--EDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVK 114

Query: 519 WNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKF 578
               E + +    K+  E+Q +  RE    +    A   S++ + + E  +      +K 
Sbjct: 115 EKEREHERR----KRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKM 170

Query: 579 SQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLS 638
            ++     E      +ER  E   + +   +    H++ + E+     KV    W +S  
Sbjct: 171 REQQKEQREQKE---RERRAEERRKEREARREVSAHHRTMREDYSD--KVKASHWSRSPP 225

Query: 639 PQDRAAY---------KEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDED 689
              R  +         KE    +R  ++ L+  +    +T+    S +E     +E++E+
Sbjct: 226 RPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEE 285

Query: 690 EDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEG-- 747
           E+EEEE+    + SE+  +  E   E+   + +E  E   +E  +E+  EDE+ E+E   
Sbjct: 286 EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHL 345

Query: 748 ----SSSSSSSSGDSSDSD 762
                S     SG+S +++
Sbjct: 346 LVVPESRFDRDSGESEEAE 364



 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 76/337 (22%), Positives = 146/337 (43%), Gaps = 45/337 (13%)

Query: 448 LSEKKKAKYKAREAA---LKAQSERKPGGEREERGKLPE---------SPKRAEEIWQQS 495
           L EKK+ K +  +A    LK   +R    +  E G+L +         SP R E+  +  
Sbjct: 17  LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMED- 75

Query: 496 VIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRY------ERELSEMR 549
                  R + D   A+K  +     M +KEK+   K     +K++      ERE  E R
Sbjct: 76  -------RGEEDDSLAIKPPQQ----MSRKEKVHHRKDEKRKEKKHARVKEKERE-HERR 123

Query: 550 APPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQ 609
                     + +++ + ++     + +  ++ L   E      ++R  E   R Q+  Q
Sbjct: 124 KRHREEQDKARREWERQKRREMAREHSRRERDRLEQLE------RKRERERKMREQQKEQ 177

Query: 610 SQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRT 669
            +++  ++ AEE++K+ +       + +S   R   ++Y    + S      P P   R 
Sbjct: 178 REQKERERRAEERRKEREAR-----REVSAHHRTMREDYSDKVKASHWSRSPPRPPRERF 232

Query: 670 TLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDE 729
            L    +  ++++ +E D   D ++  D    +S     S+ES S  E E+ +E EE++E
Sbjct: 233 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 292

Query: 730 ---DEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 763
               E+ +E+++E+E+ E E  S+S  +S  S++  S
Sbjct: 293 GSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 329



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 92/426 (21%), Positives = 164/426 (38%), Gaps = 81/426 (19%)

Query: 359 LRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFS 418
           ++ L+ + +E+++R   EEK      K +    SK+ + E G    E     +      S
Sbjct: 10  VKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEG----ELRDHCMEITIRNS 65

Query: 419 EEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREE- 477
             +R    E+R E  +S    L  +    +S K+K  ++  E   + +  R    ERE  
Sbjct: 66  PYRREDSMEDRGEEDDS----LAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHE 121

Query: 478 -RGKLPESPKRAEEIWQQSVIGDYL---ARFKNDRVKALKAMEMTWNNMEKKEKLMWIKK 533
            R +  E   +A   W++    +     +R + DR++ L+         E++ K+   +K
Sbjct: 122 RRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLE------RKRERERKMREQQK 175

Query: 534 AAEDQKRYERELSEMRAPPAATNS------------SKKMKFQGEPKKPPMNGYQKFSQE 581
              +QK  ER   E R    A               S K+K     + PP          
Sbjct: 176 EQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPR--------- 226

Query: 582 LLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQD 641
                     P +ER  E+G           +  K + EE+ ++  +  DL  + +S  +
Sbjct: 227 ----------PPRERF-ELG-----------DGRKPVKEEKMEERDLLSDL--QDISDSE 262

Query: 642 RAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGD 701
           R       S+             +       S SE  E++EE+       EEEE++E G 
Sbjct: 263 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE-------EEEEEEETGS 315

Query: 702 SSEDGGD-SSESSSEDESEDGDENEEDDE---------DEDDDEDDDEDEDNESEGSSSS 751
           +SE+  + S+E  SE+E  + +E E ++          D D  E ++ +E+       SS
Sbjct: 316 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 375

Query: 752 SSSSGD 757
           + + GD
Sbjct: 376 ALTEGD 381


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
           sapiens]
          Length = 2168

 Score = 73.9 bits (180), Expect = 5e-13
 Identities = 33/84 (39%), Positives = 56/84 (66%), Gaps = 1/84 (1%)

Query: 675 SESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDD 734
           S+  ED  EDE+++DE+E+EEDDE+ D S+D    S+S+SE ++E  +E ++DD+D+D+ 
Sbjct: 601 SKDSEDSNEDEEEDDEEEDEEDDED-DESDDSQSESDSNSESDTEGSEEEDDDDKDQDES 659

Query: 735 EDDDEDEDNESEGSSSSSSSSGDS 758
           + D E E    + + ++SS    S
Sbjct: 660 DSDTEGEKTSMKLNKTTSSVKSPS 683



 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 31/79 (39%), Positives = 48/79 (60%)

Query: 677 SEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDED 736
           S +D E+  +DE+ED+EEED+E+ +  E     SES S  ES+     EEDD+D+D DE 
Sbjct: 600 SSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDES 659

Query: 737 DDEDEDNESEGSSSSSSSS 755
           D + E  ++    + ++SS
Sbjct: 660 DSDTEGEKTSMKLNKTTSS 678



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 33/115 (28%), Positives = 58/115 (50%), Gaps = 1/115 (0%)

Query: 649 ISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 708
           +SN    +      +P  S       ++S+    +D +D +EDEEE DDE  D  +D  D
Sbjct: 568 VSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEE-DDEEEDEEDDEDD 626

Query: 709 SSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 763
            S+ S  +   + + + E  E+EDDD+ D ++ D+++EG  +S   +  +S   S
Sbjct: 627 ESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKS 681



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 24/68 (35%), Positives = 41/68 (60%)

Query: 697 DENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 756
           D +  SS+D  DS+E   ED+ E+ +E++EDDE +D   + D + ++++EGS        
Sbjct: 595 DSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDK 654

Query: 757 DSSDSDSN 764
           D  +SDS+
Sbjct: 655 DQDESDSD 662



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 25/60 (41%), Positives = 42/60 (70%), Gaps = 2/60 (3%)

Query: 707 GDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDE--DNESEGSSSSSSSSGDSSDSDSN 764
           G  S+  S  +SED +E+EE+D++E+D+EDD++DE  D++SE  S+S S +  S + D +
Sbjct: 593 GTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDD 652



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 21/79 (26%), Positives = 38/79 (48%)

Query: 686 DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 745
           D +    ++ +D N D  ED  +  E   ED+  D  ++E D   E D E  +E++D++ 
Sbjct: 595 DSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDK 654

Query: 746 EGSSSSSSSSGDSSDSDSN 764
           +   S S + G+ +    N
Sbjct: 655 DQDESDSDTEGEKTSMKLN 673



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 29/91 (31%), Positives = 55/91 (60%), Gaps = 2/91 (2%)

Query: 667 SRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE-DGGDSSESSSED-ESEDGDEN 724
           +R   Q +S+++  D   +  +D+   ++  E+  +S+ D G SS++SSE   S D D+ 
Sbjct: 209 NRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDL 268

Query: 725 EEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 755
           EED+E+ED   ++ ED+D++SE  +   S++
Sbjct: 269 EEDEEEEDQSIEESEDDDSDSESEAQHKSNN 299



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 11/108 (10%)

Query: 647  EYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDG 706
            +Y+SN R+    + G   K     + +K   + D     D  +E         G      
Sbjct: 1236 DYMSNLRRDKWVVEGKLRKLR--IIHAKKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRRK 1293

Query: 707  GDSSESSSEDESEDGDENEEDDEDEDDDED---------DDEDEDNES 745
            G  S+   +D+ +  D+ +EDDEDE+D ED         +DEDE +++
Sbjct: 1294 GGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQA 1341



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 22/65 (33%), Positives = 37/65 (56%), Gaps = 7/65 (10%)

Query: 662  PNPKSSRTTLQSKSESEEDDEEDEDD----EDEDEEEEDDENG---DSSEDGGDSSESSS 714
            P P   R      S+ ++DD++D DD    +DEDEE+++D+ G   D  ED  +  +++S
Sbjct: 1284 PTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAAS 1343

Query: 715  EDESE 719
             +E E
Sbjct: 1344 VEELE 1348



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 17/63 (26%), Positives = 32/63 (50%)

Query: 664  PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDE 723
            P   R   +   +S+ DD++D+D +D+ +E+++DE     + G  +     EDE +    
Sbjct: 1284 PTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAAS 1343

Query: 724  NEE 726
             EE
Sbjct: 1344 VEE 1346



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 1/72 (1%)

Query: 649 ISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 708
           I +K+     +   +   S +   S + SE     D DD +EDEEEE D++ + SED   
Sbjct: 229 IKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEE-DQSIEESEDDDS 287

Query: 709 SSESSSEDESED 720
            SES ++ +S +
Sbjct: 288 DSESEAQHKSNN 299



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 47/195 (24%), Positives = 83/195 (42%), Gaps = 19/195 (9%)

Query: 360  RFLESLPEEEQQRVLGEEKMLN-INKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFS 418
            + L  L  +E  R   + K+L  + K++    A +   Q+      EK K+      +  
Sbjct: 884  KLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQ 943

Query: 419  EEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREA-ALKAQSERKPGGEREE 477
            +EK +++Q+ R    E EL     R    L  KKK K +A  A  L+A+   K    R +
Sbjct: 944  QEKIKRIQQIR---MEKEL-----RAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQ 995

Query: 478  RGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAED 537
            +  L +  +R        ++    AR K +  + LK  +     + K+ KL        +
Sbjct: 996  QAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKL--------E 1047

Query: 538  QKRYERELS-EMRAP 551
            Q+R E E++ E++ P
Sbjct: 1048 QRRLELEMAKELKKP 1062



 Score = 38.5 bits (88), Expect = 0.024
 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 5/73 (6%)

Query: 658 KLRGPNPKSSRTTLQSKSESEEDDEEDEDDE-----DEDEEEEDDENGDSSEDGGDSSES 712
           K++   P+       S S+S+     D   E     D D+ EED+E  D S +  +  +S
Sbjct: 228 KIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDS 287

Query: 713 SSEDESEDGDENE 725
            SE E++    N+
Sbjct: 288 DSESEAQHKSNNQ 300



 Score = 37.4 bits (85), Expect = 0.053
 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 3/75 (4%)

Query: 663  NPKSSRTTLQSKSESEEDDEEDEDDED--EDEEEEDDENGDSSEDGGDSSESSSEDESED 720
            +P  + T  + +     D + D+DD+D  +D+ +EDDE+ +  ED         EDE E 
Sbjct: 1279 HPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDE- 1337

Query: 721  GDENEEDDEDEDDDE 735
            GD+    +E E   E
Sbjct: 1338 GDQAASVEELEKQIE 1352



 Score = 37.0 bits (84), Expect = 0.069
 Identities = 17/70 (24%), Positives = 33/70 (47%), Gaps = 4/70 (5%)

Query: 681 DEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE----EDDEDEDDDED 736
           D++      E     D ++G SS+   +   SS  D+ E+ +E E    E+ ED+D D +
Sbjct: 231 DKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSE 290

Query: 737 DDEDEDNESE 746
            +    + ++
Sbjct: 291 SEAQHKSNNQ 300



 Score = 36.6 bits (83), Expect = 0.090
 Identities = 13/42 (30%), Positives = 23/42 (54%)

Query: 721  GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 762
            GD + +DD+D+D D+  DED+++E +        +    D D
Sbjct: 1295 GDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDED 1336



 Score = 36.6 bits (83), Expect = 0.090
 Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 2/64 (3%)

Query: 692  EEEEDDENGDSSEDGGDSSESSSEDESEDGDENEE--DDEDEDDDEDDDEDEDNESEGSS 749
            + + DD++ D S+D GD  +   ED+ +   +  +  +DEDE D     E+ + + E  S
Sbjct: 1296 DSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLS 1355

Query: 750  SSSS 753
               S
Sbjct: 1356 KQQS 1359



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 15/78 (19%), Positives = 36/78 (46%)

Query: 669  TTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDD 728
            T    +    +  + D DD+D+D+ ++  +  D  E+  +  +    D  ED DE ++  
Sbjct: 1283 TPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAA 1342

Query: 729  EDEDDDEDDDEDEDNESE 746
              E+ ++  ++    +S+
Sbjct: 1343 SVEELEKQIEKLSKQQSQ 1360



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 1/44 (2%)

Query: 720  DGDENEEDDEDEDDDED-DDEDEDNESEGSSSSSSSSGDSSDSD 762
            D D +++DD+D DD  D DDEDE+++ +     +    D  + D
Sbjct: 1296 DSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGD 1339



 Score = 34.7 bits (78), Expect = 0.34
 Identities = 31/132 (23%), Positives = 57/132 (43%), Gaps = 6/132 (4%)

Query: 602 SRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRG 661
           S  Q  S S     +K  +EQ K     LD  V  +  +D+   K+ + +   S +    
Sbjct: 196 SMGQTKSTSSGGGNRKCNQEQSKNQP--LDARVDKI--KDKKPRKKAMESSSNSDSDSGT 251

Query: 662 PNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSE--SSSEDESE 719
            +  SS     S S+  E+DEE+ED   E+ E++D ++   ++   ++        D   
Sbjct: 252 SSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKA 311

Query: 720 DGDENEEDDEDE 731
           DG +  E  +++
Sbjct: 312 DGQKATEKAQEK 323



 Score = 33.1 bits (74), Expect = 0.99
 Identities = 15/56 (26%), Positives = 27/56 (48%)

Query: 709 SSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
           S  + S  E   G +++     + +D ++DE+ED+E E          D S S+S+
Sbjct: 581 SHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESD 636


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 8/96 (8%)

Query: 661 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED 720
           GPN   + T+L+S+ E EE++EE+E++E+ + EEE++E  +  E+GG+  E   E+E   
Sbjct: 392 GPNATIT-TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEE--- 447

Query: 721 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 756
                E++ D D DE+++EDE++ SEG  +   + G
Sbjct: 448 ----VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQG 479



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 39/99 (39%), Positives = 49/99 (49%), Gaps = 39/99 (39%)

Query: 678 EEDDEEDEDDEDEDEEEEDDENGDS----SED---------------------------- 705
           EE++ E+E D D DEEEE+DE   S    +ED                            
Sbjct: 444 EEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHF 503

Query: 706 --GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDED 742
             GG+ S+S SE+E    D+ EEDDEDEDDD DD+ED D
Sbjct: 504 LEGGEDSDSDSEEE----DDEEEDDEDEDDD-DDEEDGD 537



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 18/29 (62%), Positives = 27/29 (93%), Gaps = 1/29 (3%)

Query: 673 SKSESEEDDEEDEDDEDEDEEEEDDENGD 701
           S S+SEE+D+E+EDDEDED +++D+E+GD
Sbjct: 510 SDSDSEEEDDEEEDDEDED-DDDDEEDGD 537



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 15/48 (31%), Positives = 29/48 (60%)

Query: 661 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 708
           G   ++   TL      E+ D + E+++DE+E++ED+++ D  EDG +
Sbjct: 491 GAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538



 Score = 37.7 bits (86), Expect = 0.040
 Identities = 14/51 (27%), Positives = 29/51 (56%)

Query: 714 SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
           SE E E+ +E EE++E+ + +E+++E E+ E EG         +  + + +
Sbjct: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD 453



 Score = 36.6 bits (83), Expect = 0.090
 Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 4/56 (7%)

Query: 710 SESSSEDESEDGDENEEDDEDEDDDEDDDEDE---DNESEGSSSSSSSSGDSSDSD 762
           SE   E+E E+ +E EE + +E+++E ++E+E   + E  G        GD  DSD
Sbjct: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD-VDSD 457



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 14/42 (33%), Positives = 26/42 (61%), Gaps = 2/42 (4%)

Query: 706 GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEG 747
           GG  + + +     +G+E EE  E+E+++E++ E E+ E EG
Sbjct: 390 GGGPNATITTSLKSEGEEEEE--EEEEEEEEEGEGEEEEEEG 429



 Score = 30.0 bits (66), Expect = 8.4
 Identities = 11/35 (31%), Positives = 21/35 (60%)

Query: 659 LRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEE 693
           L G     S +  +   E +++DE+D+DDE++ +E
Sbjct: 504 LEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 73/333 (21%), Positives = 142/333 (42%), Gaps = 28/333 (8%)

Query: 448 LSEKKKAKYKAREAA---LKAQSERKPGGEREERGKLPE---------SPKRAEEIWQQS 495
           L EKK+ K +  +A    LK   +R    +  E G+L +         SP R E+  +  
Sbjct: 17  LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76

Query: 496 VIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQK--RYERELSEMRAPPA 553
              D     K  +  + K       + ++KEK      +AE  K  R +    E R    
Sbjct: 77  GEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKEREHERRKRHR 136

Query: 554 ATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKE 613
                 + +++ + ++     + +  ++ L   E      ++R  E   R Q+  Q +++
Sbjct: 137 EEQDKARREWERQKRREMAREHSRRERDRLEQLE------RKRERERKMREQQKEQREQK 190

Query: 614 HYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQS 673
             ++ AEE++K+ +       + +S   R   ++Y    + S      P P   R  L  
Sbjct: 191 ERERRAEERRKEREAR-----REVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGD 245

Query: 674 KSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDE---D 730
             +  ++++ +E D   D ++  D    +S     S+ES S  E E+ +E EE++E    
Sbjct: 246 GRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 305

Query: 731 EDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 763
           E+ +E+++E+E+ E E  S+S  +S  S++  S
Sbjct: 306 EESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 338



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 76/383 (19%), Positives = 153/383 (39%), Gaps = 34/383 (8%)

Query: 403 GSEKPKRPVSAMF-IFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKY----K 457
           G EK    V  +  I  E+KRR+ QEE+ E+   + +       + L E +   +     
Sbjct: 2   GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEIT 61

Query: 458 AREAALKAQSERKPGGEREERG--KLPESPKRAEEIW-QQSVIGDYLARFKNDRVKALKA 514
            R +  + +   +  GE ++    K P+   R E++  ++        R  +   +  K 
Sbjct: 62  IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKH 121

Query: 515 MEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNG 574
             +     E++      K+  E+Q +  RE    +    A   S++ + + E  +     
Sbjct: 122 ARVKEREHERR------KRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRER 175

Query: 575 YQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWV 634
            +K  ++     E      +ER  E   + +   +    H++ + E+     KV    W 
Sbjct: 176 ERKMREQQKEQREQKE---RERRAEERRKEREARREVSAHHRTMREDYSD--KVKASHWS 230

Query: 635 KSLSPQDRAAY---------KEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDE 685
           +S     R  +         KE    +R  ++ L+  +    +T+    S +E     +E
Sbjct: 231 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE 290

Query: 686 DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 745
           ++E+E+EEEE+    + SE+  +  E   E+   + +E  E   +E  +E+  EDE+ E+
Sbjct: 291 EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEEREN 350

Query: 746 EG------SSSSSSSSGDSSDSD 762
           E        S     SG+S +++
Sbjct: 351 ENHLLVVPESRFDRDSGESEEAE 373



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 93/435 (21%), Positives = 165/435 (37%), Gaps = 90/435 (20%)

Query: 359 LRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFS 418
           ++ L+ + +E+++R   EEK      K +    SK+ + E G    E     +      S
Sbjct: 10  VKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEG----ELRDHCMEITIRNS 65

Query: 419 EEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKA---REAALKAQSERKPGG-- 473
             +R    E+R E  +S    L  +    +S K+K  ++    R+   +  S    GG  
Sbjct: 66  PYRREDSMEDRGEEDDS----LAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKH 121

Query: 474 ------EREERGKLPESPKRAEEIWQQSVIGDYL---ARFKNDRVKALKAMEMTWNNMEK 524
                 E E R +  E   +A   W++    +     +R + DR++ L+         E+
Sbjct: 122 ARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLE------RKRER 175

Query: 525 KEKLMWIKKAAEDQKRYERELSEMRAPPAATNS------------SKKMKFQGEPKKPPM 572
           + K+   +K   +QK  ER   E R    A               S K+K     + PP 
Sbjct: 176 ERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPR 235

Query: 573 NGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDL 632
                              P +ER  E+G           +  K + EE+ ++  +  DL
Sbjct: 236 -------------------PPRERF-ELG-----------DGRKPVKEEKMEERDLLSDL 264

Query: 633 WVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDE 692
             + +S  +R       S+             +       S SE  E++EE+       E
Sbjct: 265 --QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE-------E 315

Query: 693 EEEDDENGDSSEDGGD-SSESSSEDESEDGDENEEDDE---------DEDDDEDDDEDED 742
           EEE++E G +SE+  + S+E  SE+E  + +E E ++          D D  E ++ +E+
Sbjct: 316 EEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 375

Query: 743 NESEGSSSSSSSSGD 757
                  SS+ + GD
Sbjct: 376 VGEGTPQSSALTEGD 390


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.125    0.352 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,282,242
Number of Sequences: 37866
Number of extensions: 1769249
Number of successful extensions: 72811
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1242
Number of HSP's successfully gapped in prelim test: 828
Number of HSP's that attempted gapping in prelim test: 18657
Number of HSP's gapped (non-prelim): 23060
length of query: 764
length of database: 18,247,518
effective HSP length: 110
effective length of query: 654
effective length of database: 14,082,258
effective search space: 9209796732
effective search space used: 9209796732
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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