Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 7657478
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens]
(311 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens] 610 e-175
gi|223718074 hydroxysteroid (17-beta) dehydrogenase 1 [Homo sapi... 219 3e-57
gi|20149619 dehydrogenase/reductase (SDR family) member 7B [Homo... 103 2e-22
gi|7706318 dehydrogenase/reductase (SDR family) member 7 [Homo s... 96 5e-20
gi|157739938 dehydrogenase/reductase (SDR family) member 7C [Hom... 93 3e-19
gi|44680136 3-hydroxybutyrate dehydrogenase, type 1 precursor [H... 93 3e-19
gi|44680133 3-hydroxybutyrate dehydrogenase, type 1 precursor [H... 93 3e-19
gi|17738292 3-hydroxybutyrate dehydrogenase, type 1 precursor [H... 93 3e-19
gi|50726952 retinol dehydrogenase 5 (11-cis and 9-cis) [Homo sap... 86 4e-17
gi|22507405 short chain dehydrogenase/reductase family 9C, membe... 85 9e-17
gi|4503817 3-ketodihydrosphingosine reductase precursor [Homo sa... 84 1e-16
gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A... 81 1e-15
gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo... 80 3e-15
gi|214010158 NADP-dependent retinol dehydrogenase/reductase [Hom... 80 3e-15
gi|214010156 NADP-dependent retinol dehydrogenase/reductase [Hom... 80 3e-15
gi|22758144 NADP-dependent retinol dehydrogenase/reductase [Homo... 80 3e-15
gi|150247226 retinol dehydrogenase 16 [Homo sapiens] 79 7e-15
gi|32483357 peroxisomal short-chain alcohol dehydrogenase [Homo ... 77 1e-14
gi|5031737 dehydrogenase/reductase member 2 isoform 2 [Homo sapi... 76 3e-14
gi|33667109 dehydrogenase/reductase member 2 isoform 1 [Homo sap... 76 3e-14
gi|119392083 hydroxysteroid (11-beta) dehydrogenase 2 [Homo sapi... 75 6e-14
gi|40254992 carbonic reductase 4 [Homo sapiens] 75 1e-13
gi|40807363 epidermal retinal dehydrogenase 2 [Homo sapiens] 74 2e-13
gi|19743808 hydroxysteroid (17-beta) dehydrogenase 6 [Homo sapiens] 72 6e-13
gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens] 70 3e-12
gi|109715829 short-chain dehydrogenase/reductase [Homo sapiens] 70 3e-12
gi|126723191 dehydrogenase/reductase (SDR family) member 4 like ... 70 3e-12
gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 65 6e-11
gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 65 6e-11
gi|7705855 hydroxysteroid (17-beta) dehydrogenase 12 [Homo sapiens] 65 8e-11
>gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens]
Length = 311
Score = 610 bits (1574), Expect = e-175
Identities = 311/311 (100%), Positives = 311/311 (100%)
Query: 1 MAAAPRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTL 60
MAAAPRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTL
Sbjct: 1 MAAAPRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTL 60
Query: 61 TVAQLDVCSDESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVR 120
TVAQLDVCSDESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVR
Sbjct: 61 TVAQLDVCSDESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVR 120
Query: 121 LVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFI 180
LVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFI
Sbjct: 121 LVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFI 180
Query: 181 SLVEPGPVVTEFEGKLLAQVSMAEFPGTDPETLHYFRDLYLPASRKLFCSVGQNPQDVVQ 240
SLVEPGPVVTEFEGKLLAQVSMAEFPGTDPETLHYFRDLYLPASRKLFCSVGQNPQDVVQ
Sbjct: 181 SLVEPGPVVTEFEGKLLAQVSMAEFPGTDPETLHYFRDLYLPASRKLFCSVGQNPQDVVQ 240
Query: 241 AIVNVISSTRPPLRRQTNIRYSPLTTLKTVDSSGSLYVRTTHRLLFRCPRLLNLGLQCLS 300
AIVNVISSTRPPLRRQTNIRYSPLTTLKTVDSSGSLYVRTTHRLLFRCPRLLNLGLQCLS
Sbjct: 241 AIVNVISSTRPPLRRQTNIRYSPLTTLKTVDSSGSLYVRTTHRLLFRCPRLLNLGLQCLS 300
Query: 301 CGCLPTRVRPR 311
CGCLPTRVRPR
Sbjct: 301 CGCLPTRVRPR 311
>gi|223718074 hydroxysteroid (17-beta) dehydrogenase 1 [Homo
sapiens]
Length = 328
Score = 219 bits (557), Expect = 3e-57
Identities = 134/286 (46%), Positives = 174/286 (60%), Gaps = 5/286 (1%)
Query: 4 APRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETL-EAAAGEALGQ-TLT 61
A VLI+GCSSGIGL LAV+LA DP + ++V AT+RDL + L EAA A +L
Sbjct: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61
Query: 62 VAQLDVCSDESVAQCLSCI-QGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVR 120
QLDV +SVA + +G VDVLV NAG+GL+GPLE L A+ +V D N G VR
Sbjct: 62 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121
Query: 121 LVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFI 180
+++A LP MKRR G ++V SV GL G+ FNDVY ASKFALEG ESLA+ LL F + +
Sbjct: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181
Query: 181 SLVEPGPVVTEFEGKLLAQVSMAEFPGTDPETLHYFRDLYLPASRKLFCSVGQNPQDVVQ 240
SL+E GPV T F K+L TD T H F YL S+++F QNP++V +
Sbjct: 182 SLIECGPVHTAFMEKVLGSPEEV-LDRTDIHTFHRFYQ-YLAHSKQVFREAAQNPEEVAE 239
Query: 241 AIVNVISSTRPPLRRQTNIRYSPLTTLKTVDSSGSLYVRTTHRLLF 286
+ + + +P LR T R+ PL ++ D SGS YV HR +F
Sbjct: 240 VFLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVF 285
>gi|20149619 dehydrogenase/reductase (SDR family) member 7B [Homo
sapiens]
Length = 325
Score = 103 bits (257), Expect = 2e-22
Identities = 80/253 (31%), Positives = 121/253 (47%), Gaps = 36/253 (14%)
Query: 8 VLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETL--EAAAGEALG-QT----- 59
V+I+G +SG+G E A K +V R+ G E L E A A QT
Sbjct: 55 VVITGATSGLGKECAKVFYAAGAK---LVLCGRNGGALEELIRELTASHATKVQTHKPYL 111
Query: 60 ----LTVAQLDVCSDESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNF 115
LT + V + + QC G VD+LVNNAG+ G + ++ + V +TN+
Sbjct: 112 VTFDLTDSGAIVAAAAEILQCF----GYVDILVNNAGISYRGTIMDTTVDVDKRVMETNY 167
Query: 116 FGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQ 175
FG V L KA+LP M +RRQGHIV ISS+ G + F YAASK A + FF+ L ++ Q
Sbjct: 168 FGPVALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQ 227
Query: 176 FNIFISLVEPGPVVTEF-------EGKLLAQVSMAEFPGTDPETLHYFRDLYLPASRKLF 228
+ I ++++ PG + T +G + G P + ++ +
Sbjct: 228 YEIEVTVISPGYIHTNLSVNAITADGSRYGVMDTTTAQGRSP----------VEVAQDVL 277
Query: 229 CSVGQNPQDVVQA 241
+VG+ +DV+ A
Sbjct: 278 AAVGKKKKDVILA 290
>gi|7706318 dehydrogenase/reductase (SDR family) member 7 [Homo
sapiens]
Length = 339
Score = 95.5 bits (236), Expect = 5e-20
Identities = 69/202 (34%), Positives = 104/202 (51%), Gaps = 11/202 (5%)
Query: 8 VLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAA---GEALGQTLTVAQ 64
V ++G SSGIG ELA QL+ K +V + R + + E ++ G + + V
Sbjct: 53 VWVTGASSGIGEELAYQLS---KLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLP 109
Query: 65 LDVC---SDESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRL 121
LD+ S E+ + + G +D+LVNN GM SL + + + N+ G V L
Sbjct: 110 LDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSL 169
Query: 122 VKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQF-NIFI 180
K VLP M R+QG IV ++S++G+ V + Y ASK AL GFF L +L + I +
Sbjct: 170 TKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIV 229
Query: 181 SLVEPGPVVTEF-EGKLLAQVS 201
S + PGPV + E L +V+
Sbjct: 230 SNICPGPVQSNIVENSLAGEVT 251
>gi|157739938 dehydrogenase/reductase (SDR family) member 7C [Homo
sapiens]
Length = 311
Score = 93.2 bits (230), Expect = 3e-19
Identities = 62/191 (32%), Positives = 98/191 (51%), Gaps = 10/191 (5%)
Query: 2 AAAPRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLT 61
A + V+I+ SG+G E A ++ H R +V ++ + E L A + T
Sbjct: 34 AVQNKVVVITDAISGLGKECA-RVFHTGGAR--LVLCGKNWERLENLYDALISVADPSKT 90
Query: 62 VAQLDVCSDESVAQCLSCIQGEV-------DVLVNNAGMGLVGPLEGLSLAAMQNVFDTN 114
V D S C+ + EV D+L+NNA + + GP +SL + + D N
Sbjct: 91 FTPKLVLLDLSDISCVPDVAKEVLDCYGCVDILINNASVKVKGPAHKISLELDKKIMDAN 150
Query: 115 FFGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLL 174
+FG + L KA+LP M RR G IV+++++ G G+ F YAASK A GFF+ L ++
Sbjct: 151 YFGPITLTKALLPNMISRRTGQIVLVNNIQGKFGIPFRTTYAASKHAALGFFDCLRAEVE 210
Query: 175 QFNIFISLVEP 185
++++ IS V P
Sbjct: 211 EYDVVISTVSP 221
>gi|44680136 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
sapiens]
Length = 343
Score = 92.8 bits (229), Expect = 3e-19
Identities = 77/267 (28%), Positives = 123/267 (46%), Gaps = 26/267 (9%)
Query: 6 RTVLISGCSSGIGLELAVQLAHDPKKRYQVVA--TMRDLGKKETLEAAAGEALGQTLTVA 63
+ VL++GC SG G LA H K + V A M+D G E + + L
Sbjct: 56 KAVLVTGCDSGFGFSLA---KHLHSKGFLVFAGCLMKDKGHDGVKELDSLNS--DRLRTV 110
Query: 64 QLDVCSDESVAQCLSCIQGEVDV-------LVNNAGMGLVGPLEGLSLAAMQNVFDTNFF 116
QL+VCS E V + + ++ + LVNNAG+ G +E SL + V + N +
Sbjct: 111 QLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLW 170
Query: 117 GAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQF 176
G VR+ K+ LP + RR +G +V ISS++G Y +KF +E F + L ++
Sbjct: 171 GTVRMTKSFLP-LIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPL 229
Query: 177 NIFISLVEPGPVV--TEFEGKLLAQVSMAEFPGTDPETLH------YFRDLYLPASRKLF 228
+ +S+VEPG + T Q + PE + YF + A + +
Sbjct: 230 GVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKI--AKMETY 287
Query: 229 CSVGQ-NPQDVVQAIVNVISSTRPPLR 254
CS G + V+ A+ + +++T P R
Sbjct: 288 CSSGSTDTSPVIDAVTHALTATTPYTR 314
>gi|44680133 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
sapiens]
Length = 343
Score = 92.8 bits (229), Expect = 3e-19
Identities = 77/267 (28%), Positives = 123/267 (46%), Gaps = 26/267 (9%)
Query: 6 RTVLISGCSSGIGLELAVQLAHDPKKRYQVVA--TMRDLGKKETLEAAAGEALGQTLTVA 63
+ VL++GC SG G LA H K + V A M+D G E + + L
Sbjct: 56 KAVLVTGCDSGFGFSLA---KHLHSKGFLVFAGCLMKDKGHDGVKELDSLNS--DRLRTV 110
Query: 64 QLDVCSDESVAQCLSCIQGEVDV-------LVNNAGMGLVGPLEGLSLAAMQNVFDTNFF 116
QL+VCS E V + + ++ + LVNNAG+ G +E SL + V + N +
Sbjct: 111 QLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLW 170
Query: 117 GAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQF 176
G VR+ K+ LP + RR +G +V ISS++G Y +KF +E F + L ++
Sbjct: 171 GTVRMTKSFLP-LIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPL 229
Query: 177 NIFISLVEPGPVV--TEFEGKLLAQVSMAEFPGTDPETLH------YFRDLYLPASRKLF 228
+ +S+VEPG + T Q + PE + YF + A + +
Sbjct: 230 GVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKI--AKMETY 287
Query: 229 CSVGQ-NPQDVVQAIVNVISSTRPPLR 254
CS G + V+ A+ + +++T P R
Sbjct: 288 CSSGSTDTSPVIDAVTHALTATTPYTR 314
>gi|17738292 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
sapiens]
Length = 343
Score = 92.8 bits (229), Expect = 3e-19
Identities = 77/267 (28%), Positives = 123/267 (46%), Gaps = 26/267 (9%)
Query: 6 RTVLISGCSSGIGLELAVQLAHDPKKRYQVVA--TMRDLGKKETLEAAAGEALGQTLTVA 63
+ VL++GC SG G LA H K + V A M+D G E + + L
Sbjct: 56 KAVLVTGCDSGFGFSLA---KHLHSKGFLVFAGCLMKDKGHDGVKELDSLNS--DRLRTV 110
Query: 64 QLDVCSDESVAQCLSCIQGEVDV-------LVNNAGMGLVGPLEGLSLAAMQNVFDTNFF 116
QL+VCS E V + + ++ + LVNNAG+ G +E SL + V + N +
Sbjct: 111 QLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLW 170
Query: 117 GAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQF 176
G VR+ K+ LP + RR +G +V ISS++G Y +KF +E F + L ++
Sbjct: 171 GTVRMTKSFLP-LIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPL 229
Query: 177 NIFISLVEPGPVV--TEFEGKLLAQVSMAEFPGTDPETLH------YFRDLYLPASRKLF 228
+ +S+VEPG + T Q + PE + YF + A + +
Sbjct: 230 GVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKI--AKMETY 287
Query: 229 CSVGQ-NPQDVVQAIVNVISSTRPPLR 254
CS G + V+ A+ + +++T P R
Sbjct: 288 CSSGSTDTSPVIDAVTHALTATTPYTR 314
>gi|50726952 retinol dehydrogenase 5 (11-cis and 9-cis) [Homo
sapiens]
Length = 318
Score = 85.9 bits (211), Expect = 4e-17
Identities = 65/192 (33%), Positives = 99/192 (51%), Gaps = 15/192 (7%)
Query: 1 MAAAPRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTL 60
+ A+ V I+GC SG G LA+QL ++ ++V+A+ E L+ A L TL
Sbjct: 24 LPASNAFVFITGCDSGFGRLLALQL---DQRGFRVLASCLTPSGAEDLQRVASSRLHTTL 80
Query: 61 TVAQLDVCSDESVAQCLSCIQGEVDV-----LVNNAGM-GLVGPLEGLSLAAMQNVFDTN 114
LD+ +SV Q ++ V LVNNAG+ G++GP L+ Q V + N
Sbjct: 81 ----LDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVN 136
Query: 115 FFGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLL 174
G + + A+LP +++ R G ++ I+SV+G Y SKF LE F +SL +
Sbjct: 137 TMGPIGVTLALLPLLQQAR-GRVINITSVLGRLAANGGG-YCVSKFGLEAFSDSLRRDVA 194
Query: 175 QFNIFISLVEPG 186
F I +S+VEPG
Sbjct: 195 HFGIRVSIVEPG 206
>gi|22507405 short chain dehydrogenase/reductase family 9C, member 7
[Homo sapiens]
Length = 313
Score = 84.7 bits (208), Expect = 9e-17
Identities = 83/278 (29%), Positives = 122/278 (43%), Gaps = 26/278 (9%)
Query: 8 VLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDV 67
V I+GC SG G LA QL + QV+A + L+ L TL LDV
Sbjct: 28 VFITGCDSGFGNLLAKQLVD---RGMQVLAACFTEEGSQKLQRDTSYRLQTTL----LDV 80
Query: 68 CSDESVAQCLSCIQGEVD-----VLVNNAGMGLV-GPLEGLSLAAMQNVFDTNFFGAVRL 121
ES+ ++ +V LVNNAG+GL GP E L+ V + N G + +
Sbjct: 81 TKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIEV 140
Query: 122 VKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFIS 181
+LP +KR R G +V +SS G VI Y SKF +E F +S+ +L F + +
Sbjct: 141 TLHMLPMVKRAR-GRVVNMSSSGGRVAVIGGG-YCVSKFGVEAFSDSIRRELYYFGVKVC 198
Query: 182 LVEPGPVVTEFEGKLLAQVSMAEFPGTDPETLH------YFRDLYLPASRKLFCSVGQNP 235
++EPG T GK + M + P+ YFR +Y + +
Sbjct: 199 IIEPGNYRTAILGKENLESRMRKLWERLPQETRDSYGEDYFR-IYTDKLKNIMQVAEPRV 257
Query: 236 QDVVQAIVNVISSTRPPLR----RQTNIRYSPLTTLKT 269
+DV+ ++ + I S P +R + Y PL L T
Sbjct: 258 RDVINSMEHAIVSRSPRIRYNPGLDAKLLYIPLAKLPT 295
>gi|4503817 3-ketodihydrosphingosine reductase precursor [Homo
sapiens]
Length = 332
Score = 84.3 bits (207), Expect = 1e-16
Identities = 57/188 (30%), Positives = 99/188 (52%), Gaps = 16/188 (8%)
Query: 8 VLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDV 67
V+++G SSGIG +A++ K+ + R+ ++ L A E ++ Q+ +
Sbjct: 35 VVVTGGSSGIGKCIAIECY---KQGAFITLVARN---EDKLLQAKKEIEMHSINDKQVVL 88
Query: 68 CSDESVAQCLSCIQ----------GEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFG 117
C V+Q + ++ G VD+LVN AGM + G E L ++ + + N+ G
Sbjct: 89 CISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLG 148
Query: 118 AVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFN 177
+V +AV+ MK RR G IV +SS G G+ Y+ASKFA+ G E+L +++ +N
Sbjct: 149 SVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYN 208
Query: 178 IFISLVEP 185
++I++ P
Sbjct: 209 VYITVAYP 216
>gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A
[Homo sapiens]
Length = 300
Score = 81.3 bits (199), Expect = 1e-15
Identities = 55/176 (31%), Positives = 85/176 (48%), Gaps = 9/176 (5%)
Query: 2 AAAPRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAG-EALGQTL 60
+ A VLI+G GIG + + A + Q + + D+ K+ E AA LG T
Sbjct: 33 SVAGEIVLITGAGHGIGRQTTYEFA-----KRQSILVLWDINKRGVEETAAECRKLGVTA 87
Query: 61 TVAQLDVCSDESVAQCLSCIQ---GEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFG 117
+D + E + + L+ ++ G+V ++VNNAG L + F+ N G
Sbjct: 88 HAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILG 147
Query: 118 AVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQL 173
+ KA+LP M R GHIV ++SV G +G+ + Y +SKFA GF L +L
Sbjct: 148 HFWITKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSEL 203
>gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo
sapiens]
Length = 319
Score = 79.7 bits (195), Expect = 3e-15
Identities = 69/257 (26%), Positives = 123/257 (47%), Gaps = 24/257 (9%)
Query: 8 VLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDV 67
+ I+GC SG G LA + KK + V+A L+A E L L LDV
Sbjct: 32 IFITGCDSGFG-NLAARTFD--KKGFHVIAACLTESGSTALKAETSERLRTVL----LDV 84
Query: 68 CSDESVAQCLSCIQGEVDV-----LVNNAGM-GLVGPLEGLSLAAMQNVFDTNFFGAVRL 121
E+V + ++ +V L+NNAG+ G++ P + L+L + + N FG + +
Sbjct: 85 TDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISV 144
Query: 122 VKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFIS 181
+LP +K+ QG ++ +SSV G ++ Y SK+A+EGF +SL + F + +S
Sbjct: 145 TLNMLPLVKKA-QGRVINVSSVGGRLAIVGGG-YTPSKYAVEGFNDSLRRDMKAFGVHVS 202
Query: 182 LVEPGPVVTEFEGKL-LAQVSMAEFPGTDPETLHYFRDLYLPAS------RKLFCSVGQN 234
+EPG T + + + +A + P+ + + Y+ S K + ++ +
Sbjct: 203 CIEPGLFKTNLADPVKVIEKKLAIWEQLSPDIKQQYGEGYIEKSLDKLKGNKSYVNMDLS 262
Query: 235 PQDVVQAIVNVISSTRP 251
P VV+ + + ++S P
Sbjct: 263 P--VVECMDHALTSLFP 277
>gi|214010158 NADP-dependent retinol dehydrogenase/reductase [Homo
sapiens]
Length = 319
Score = 79.7 bits (195), Expect = 3e-15
Identities = 69/257 (26%), Positives = 123/257 (47%), Gaps = 24/257 (9%)
Query: 8 VLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDV 67
+ I+GC SG G LA + KK + V+A L+A E L L LDV
Sbjct: 32 IFITGCDSGFG-NLAARTFD--KKGFHVIAACLTESGSTALKAETSERLRTVL----LDV 84
Query: 68 CSDESVAQCLSCIQGEVDV-----LVNNAGM-GLVGPLEGLSLAAMQNVFDTNFFGAVRL 121
E+V + ++ +V L+NNAG+ G++ P + L+L + + N FG + +
Sbjct: 85 TDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISV 144
Query: 122 VKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFIS 181
+LP +K+ QG ++ +SSV G ++ Y SK+A+EGF +SL + F + +S
Sbjct: 145 TLNMLPLVKKA-QGRVINVSSVGGRLAIVGGG-YTPSKYAVEGFNDSLRRDMKAFGVHVS 202
Query: 182 LVEPGPVVTEFEGKL-LAQVSMAEFPGTDPETLHYFRDLYLPAS------RKLFCSVGQN 234
+EPG T + + + +A + P+ + + Y+ S K + ++ +
Sbjct: 203 CIEPGLFKTNLADPVKVIEKKLAIWEQLSPDIKQQYGEGYIEKSLDKLKGNKSYVNMDLS 262
Query: 235 PQDVVQAIVNVISSTRP 251
P VV+ + + ++S P
Sbjct: 263 P--VVECMDHALTSLFP 277
>gi|214010156 NADP-dependent retinol dehydrogenase/reductase [Homo
sapiens]
Length = 319
Score = 79.7 bits (195), Expect = 3e-15
Identities = 69/257 (26%), Positives = 123/257 (47%), Gaps = 24/257 (9%)
Query: 8 VLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDV 67
+ I+GC SG G LA + KK + V+A L+A E L L LDV
Sbjct: 32 IFITGCDSGFG-NLAARTFD--KKGFHVIAACLTESGSTALKAETSERLRTVL----LDV 84
Query: 68 CSDESVAQCLSCIQGEVDV-----LVNNAGM-GLVGPLEGLSLAAMQNVFDTNFFGAVRL 121
E+V + ++ +V L+NNAG+ G++ P + L+L + + N FG + +
Sbjct: 85 TDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISV 144
Query: 122 VKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFIS 181
+LP +K+ QG ++ +SSV G ++ Y SK+A+EGF +SL + F + +S
Sbjct: 145 TLNMLPLVKKA-QGRVINVSSVGGRLAIVGGG-YTPSKYAVEGFNDSLRRDMKAFGVHVS 202
Query: 182 LVEPGPVVTEFEGKL-LAQVSMAEFPGTDPETLHYFRDLYLPAS------RKLFCSVGQN 234
+EPG T + + + +A + P+ + + Y+ S K + ++ +
Sbjct: 203 CIEPGLFKTNLADPVKVIEKKLAIWEQLSPDIKQQYGEGYIEKSLDKLKGNKSYVNMDLS 262
Query: 235 PQDVVQAIVNVISSTRP 251
P VV+ + + ++S P
Sbjct: 263 P--VVECMDHALTSLFP 277
>gi|22758144 NADP-dependent retinol dehydrogenase/reductase [Homo
sapiens]
Length = 319
Score = 79.7 bits (195), Expect = 3e-15
Identities = 69/257 (26%), Positives = 123/257 (47%), Gaps = 24/257 (9%)
Query: 8 VLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDV 67
+ I+GC SG G LA + KK + V+A L+A E L L LDV
Sbjct: 32 IFITGCDSGFG-NLAARTFD--KKGFHVIAACLTESGSTALKAETSERLRTVL----LDV 84
Query: 68 CSDESVAQCLSCIQGEVDV-----LVNNAGM-GLVGPLEGLSLAAMQNVFDTNFFGAVRL 121
E+V + ++ +V L+NNAG+ G++ P + L+L + + N FG + +
Sbjct: 85 TDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISV 144
Query: 122 VKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFIS 181
+LP +K+ QG ++ +SSV G ++ Y SK+A+EGF +SL + F + +S
Sbjct: 145 TLNMLPLVKKA-QGRVINVSSVGGRLAIVGGG-YTPSKYAVEGFNDSLRRDMKAFGVHVS 202
Query: 182 LVEPGPVVTEFEGKL-LAQVSMAEFPGTDPETLHYFRDLYLPAS------RKLFCSVGQN 234
+EPG T + + + +A + P+ + + Y+ S K + ++ +
Sbjct: 203 CIEPGLFKTNLADPVKVIEKKLAIWEQLSPDIKQQYGEGYIEKSLDKLKGNKSYVNMDLS 262
Query: 235 PQDVVQAIVNVISSTRP 251
P VV+ + + ++S P
Sbjct: 263 P--VVECMDHALTSLFP 277
>gi|150247226 retinol dehydrogenase 16 [Homo sapiens]
Length = 317
Score = 78.6 bits (192), Expect = 7e-15
Identities = 66/194 (34%), Positives = 99/194 (51%), Gaps = 15/194 (7%)
Query: 8 VLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDV 67
V I+GC SG G LA QL D + + A + + G E L + L +T+T LDV
Sbjct: 32 VFITGCDSGFGKLLARQL--DARGLRVLAACLTEKGA-EQLRGQTSDRL-ETVT---LDV 84
Query: 68 CSDESVAQCLS----CIQGE-VDVLVNNAGMGL-VGPLEGLSLAAMQNVFDTNFFGAVRL 121
ESVA C++ + + LVNNAG+ L P E L+ + D N G + +
Sbjct: 85 TKTESVAAAAQWVKECVRDKGLWGLVNNAGISLPTAPNELLTKQDFVTILDVNLLGVIDV 144
Query: 122 VKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFIS 181
++LP + RR +G +V +SSVMG +F Y SK+ +E F +SL +L F + ++
Sbjct: 145 TLSLLP-LVRRARGRVVNVSSVMGRVS-LFGGGYCISKYGVEAFSDSLRRELSYFGVKVA 202
Query: 182 LVEPGPVVTEFEGK 195
++EPG T K
Sbjct: 203 MIEPGYFKTAVTSK 216
>gi|32483357 peroxisomal short-chain alcohol dehydrogenase [Homo
sapiens]
Length = 278
Score = 77.4 bits (189), Expect = 1e-14
Identities = 55/195 (28%), Positives = 92/195 (47%), Gaps = 4/195 (2%)
Query: 4 APRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVA 63
A + L++ + GIG +A +LA D + VV++ + + + GE L T TV
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGA--HVVVSSRKQQNVDQAVATLQGEGLSVTGTVC 88
Query: 64 QLDVCSD-ESVAQCLSCIQGEVDVLVNNAGMG-LVGPLEGLSLAAMQNVFDTNFFGAVRL 121
+ D E + + G +D+LV+NA + G + ++ D N +
Sbjct: 89 HVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALM 148
Query: 122 VKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFIS 181
KAV+P M++R G +V++SS+ Y SK AL G ++LAI+L NI ++
Sbjct: 149 TKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVN 208
Query: 182 LVEPGPVVTEFEGKL 196
+ PG + T F L
Sbjct: 209 CLAPGLIKTSFSRML 223
>gi|5031737 dehydrogenase/reductase member 2 isoform 2 [Homo
sapiens]
Length = 280
Score = 76.3 bits (186), Expect = 3e-14
Identities = 64/197 (32%), Positives = 102/197 (51%), Gaps = 17/197 (8%)
Query: 4 APRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVA 63
A R +++G +SGIG +A +LA D VV + R K++ ++ A + G+ L+VA
Sbjct: 35 ANRVAVVTGSTSGIGFAIARRLARDGA---HVVISSR---KQQNVDRAMAKLQGEGLSVA 88
Query: 64 QLDVCS-------DESVAQCLSCIQGEVDVLVNNAGMG-LVGPLEGLSLAAMQNVFDTNF 115
+ VC ++ VA+ L G VD LV +AG+ LVG G S + N
Sbjct: 89 GI-VCHVGKAEDREQLVAKALEHCGG-VDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNV 146
Query: 116 FGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQ 175
L+ +LP M+ RR G ++++SS+ V+ VY SK AL G +LA++L
Sbjct: 147 KSPALLLSQLLPYMENRR-GAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAP 205
Query: 176 FNIFISLVEPGPVVTEF 192
+I ++ V PG + T+F
Sbjct: 206 KDIRVNCVVPGIIKTDF 222
>gi|33667109 dehydrogenase/reductase member 2 isoform 1 [Homo
sapiens]
Length = 300
Score = 76.3 bits (186), Expect = 3e-14
Identities = 64/197 (32%), Positives = 102/197 (51%), Gaps = 17/197 (8%)
Query: 4 APRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVA 63
A R +++G +SGIG +A +LA D VV + R K++ ++ A + G+ L+VA
Sbjct: 35 ANRVAVVTGSTSGIGFAIARRLARDGA---HVVISSR---KQQNVDRAMAKLQGEGLSVA 88
Query: 64 QLDVCS-------DESVAQCLSCIQGEVDVLVNNAGMG-LVGPLEGLSLAAMQNVFDTNF 115
+ VC ++ VA+ L G VD LV +AG+ LVG G S + N
Sbjct: 89 GI-VCHVGKAEDREQLVAKALEHCGG-VDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNV 146
Query: 116 FGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQ 175
L+ +LP M+ RR G ++++SS+ V+ VY SK AL G +LA++L
Sbjct: 147 KSPALLLSQLLPYMENRR-GAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAP 205
Query: 176 FNIFISLVEPGPVVTEF 192
+I ++ V PG + T+F
Sbjct: 206 KDIRVNCVVPGIIKTDF 222
>gi|119392083 hydroxysteroid (11-beta) dehydrogenase 2 [Homo
sapiens]
Length = 405
Score = 75.5 bits (184), Expect = 6e-14
Identities = 57/197 (28%), Positives = 93/197 (47%), Gaps = 12/197 (6%)
Query: 1 MAAAPRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTL 60
+ A R VLI+GC SG G E A +L + V+AT+ +L +E L
Sbjct: 78 LPVATRAVLITGCDSGFGKETAKKL---DSMGFTVLATVLELNSPGAIELRT--CCSPRL 132
Query: 61 TVAQLDVCSDESVAQCLSCIQGEVDV-----LVNNAGMG-LVGPLEGLSLAAMQNVFDTN 114
+ Q+D+ +++ L + LVNNAG +V E +A ++ + N
Sbjct: 133 RLLQMDLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVN 192
Query: 115 FFGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLL 174
FFGA+ L K +LP + R +G IV + S G Y SK A+ ++ + +LL
Sbjct: 193 FFGALELTKGLLP-LLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELL 251
Query: 175 QFNIFISLVEPGPVVTE 191
+ + +S+++PG TE
Sbjct: 252 PWGVKVSIIQPGCFKTE 268
>gi|40254992 carbonic reductase 4 [Homo sapiens]
Length = 237
Score = 74.7 bits (182), Expect = 1e-13
Identities = 60/185 (32%), Positives = 95/185 (51%), Gaps = 10/185 (5%)
Query: 10 ISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDVCS 69
+ G S GIG +A +A +K Y++ R+L E +AAAG+ G L + DV
Sbjct: 7 VFGGSRGIGRAVAQLMA---RKGYRLAVIARNL---EGAKAAAGDLGGDHLAFS-CDVAK 59
Query: 70 DESVAQCLSCIQ---GEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVL 126
+ V ++ G V+ LVN AG+ G L M + TN G++ KA +
Sbjct: 60 EHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM 119
Query: 127 PGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFISLVEPG 186
M +++ G IV + S++GL+G VY+ASK L GF +LA ++ + I +++V PG
Sbjct: 120 RTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179
Query: 187 PVVTE 191
V T+
Sbjct: 180 FVHTD 184
>gi|40807363 epidermal retinal dehydrogenase 2 [Homo sapiens]
Length = 309
Score = 73.6 bits (179), Expect = 2e-13
Identities = 64/175 (36%), Positives = 82/175 (46%), Gaps = 12/175 (6%)
Query: 4 APRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAA--AGEALGQTLT 61
A VLI+G SG+G LA+Q A R V + D+ K+ E A EA G T
Sbjct: 39 AGEIVLITGAGSGLGRLLALQFA-----RLGSVLVLWDINKEGNEETCKMAREA-GATRV 92
Query: 62 VAQLDVCSDES----VAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFG 117
A CS + VA + G+V +L+NNAG+ M+ FD NF
Sbjct: 93 HAYTCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKA 152
Query: 118 AVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQ 172
+ KA LP M GH+V ISS GL GV Y ASKFA GF ES+ ++
Sbjct: 153 HLWTYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVE 207
>gi|19743808 hydroxysteroid (17-beta) dehydrogenase 6 [Homo sapiens]
Length = 317
Score = 72.0 bits (175), Expect = 6e-13
Identities = 80/262 (30%), Positives = 121/262 (46%), Gaps = 28/262 (10%)
Query: 8 VLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDV 67
V I+GC SG G LA QL D + + A + + G E L + L +T+T LDV
Sbjct: 32 VFITGCDSGFGNLLARQL--DARGLRVLAACLTEKGA-EQLRGQTSDRL-ETVT---LDV 84
Query: 68 CSDESVAQCLSCIQGEVDV-----LVNNAGMGLVGPL---EGLSLAAMQNVFDTNFFGAV 119
ES+A ++ V LVNNAG ++ P+ E L+ N+ N G +
Sbjct: 85 TKMESIAAATQWVKEHVGDRGLWGLVNNAG--ILTPITLCEWLNTEDSMNMLKVNLIGVI 142
Query: 120 RLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIF 179
++ ++LP + RR +G IV +SS++G + F Y SK+ +E F + L ++ F +
Sbjct: 143 QVTLSMLP-LVRRARGRIVNVSSILG-RVAFFVGGYCVSKYGVEAFSDILRREIQHFGVK 200
Query: 180 ISLVEPGPVVTEFEGKLLA----QVSMAEFPGTDPETL--HYFRDLY-LPASRKLFCSVG 232
IS+VEPG T + + S E P ET YF LY + L CS
Sbjct: 201 ISIVEPGYFRTGMTNMTQSLERMKQSWKEAPKHIKETYGQQYFDALYNIMKEGLLNCSTN 260
Query: 233 QNPQDVVQAIVNVISSTRPPLR 254
N V + + ++S P R
Sbjct: 261 LNL--VTDCMEHALTSVHPRTR 280
>gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens]
Length = 300
Score = 69.7 bits (169), Expect = 3e-12
Identities = 54/174 (31%), Positives = 79/174 (45%), Gaps = 7/174 (4%)
Query: 8 VLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDV 67
VLI+G GIG A + A K V+ + G +ET AA + LG + +D
Sbjct: 39 VLITGAGHGIGRLTAYEFAKLKSKL--VLWDINKHGLEET--AAKCKGLGAKVHTFVVDC 94
Query: 68 CSDESVAQCLSCIQ---GEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKA 124
+ E + ++ G+V +LVNNAG+ L ++ F+ N KA
Sbjct: 95 SNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKA 154
Query: 125 VLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNI 178
LP M + GHIV ++S G V F Y +SKFA GF ++L +L I
Sbjct: 155 FLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQI 208
>gi|109715829 short-chain dehydrogenase/reductase [Homo sapiens]
Length = 260
Score = 69.7 bits (169), Expect = 3e-12
Identities = 69/253 (27%), Positives = 111/253 (43%), Gaps = 32/253 (12%)
Query: 6 RTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEA-LGQTLTVAQ 64
R L++G S GIG +A L K VV R +G E L A A TL +
Sbjct: 12 RLALVTGASGGIGAAVARALVQQGLK---VVGCARTVGNIEELAAECKSAGYPGTLIPYR 68
Query: 65 LDVCSDESVAQCLSCIQGE---VDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRL 121
D+ ++E + S I+ + VD+ +NNAG+ L S + +++F+ N
Sbjct: 69 CDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSIC 128
Query: 122 VKAVLPGMKRRR--QGHIVVISSVMG--LQGVIFNDVYAASKFALEGFFESLAIQL--LQ 175
+ MK R GHI+ I+S+ G + + Y+A+K+A+ E L +L Q
Sbjct: 129 TREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQ 188
Query: 176 FNIFISLVEPGPVVTEFEGKLLAQVSMAEFPGTDPETLHYFRDLYLPASRKLFCSVGQNP 235
+I + + PG V T+F KL DPE ++ C P
Sbjct: 189 THIRATCISPGVVETQFAFKL---------HDKDPEKA-------AATYEQMKC---LKP 229
Query: 236 QDVVQAIVNVISS 248
+DV +A++ V+S+
Sbjct: 230 EDVAEAVIYVLST 242
>gi|126723191 dehydrogenase/reductase (SDR family) member 4 like 2
[Homo sapiens]
Length = 232
Score = 69.7 bits (169), Expect = 3e-12
Identities = 50/178 (28%), Positives = 84/178 (47%), Gaps = 4/178 (2%)
Query: 6 RTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQL 65
+ L++ + GIG +A +LA D + + VV++ + + + GE L T TV +
Sbjct: 33 KVALVTASTDGIGFAIARRLAQD--RAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 90
Query: 66 DVCSD-ESVAQCLSCIQGEVDVLVNNAGMG-LVGPLEGLSLAAMQNVFDTNFFGAVRLVK 123
D E + + G +D+LV+NA + G L ++ D N + K
Sbjct: 91 GKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTK 150
Query: 124 AVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFIS 181
AV+P M++R G +V++SS+ Y SK AL G +LAI+L NI ++
Sbjct: 151 AVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIELAPRNIRVN 208
>gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
Length = 292
Score = 65.5 bits (158), Expect = 6e-11
Identities = 61/203 (30%), Positives = 92/203 (45%), Gaps = 15/203 (7%)
Query: 6 RTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAA------GEALGQT 59
+ V+++G S GIG E+A LA K VV T R KETL+ G A
Sbjct: 35 KKVIVTGASKGIGREMAYHLA---KMGAHVVVTARS---KETLQKVVSHCLELGAASAHY 88
Query: 60 LTVAQLDVCSDESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAV 119
+ D+ E + G +D+L+ N L + ++ + NF V
Sbjct: 89 IAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYV 148
Query: 120 RLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESL--AIQLLQFN 177
L A LP M ++ G IVV+SS+ G Y+ASKFAL+GFF S+ + + N
Sbjct: 149 VLTVAALP-MLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVN 207
Query: 178 IFISLVEPGPVVTEFEGKLLAQV 200
+ I+L G + TE K ++ +
Sbjct: 208 VSITLCVLGLIDTETAMKAVSGI 230
>gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
Length = 292
Score = 65.5 bits (158), Expect = 6e-11
Identities = 61/203 (30%), Positives = 92/203 (45%), Gaps = 15/203 (7%)
Query: 6 RTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAA------GEALGQT 59
+ V+++G S GIG E+A LA K VV T R KETL+ G A
Sbjct: 35 KKVIVTGASKGIGREMAYHLA---KMGAHVVVTARS---KETLQKVVSHCLELGAASAHY 88
Query: 60 LTVAQLDVCSDESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAV 119
+ D+ E + G +D+L+ N L + ++ + NF V
Sbjct: 89 IAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYV 148
Query: 120 RLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESL--AIQLLQFN 177
L A LP M ++ G IVV+SS+ G Y+ASKFAL+GFF S+ + + N
Sbjct: 149 VLTVAALP-MLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVN 207
Query: 178 IFISLVEPGPVVTEFEGKLLAQV 200
+ I+L G + TE K ++ +
Sbjct: 208 VSITLCVLGLIDTETAMKAVSGI 230
>gi|7705855 hydroxysteroid (17-beta) dehydrogenase 12 [Homo sapiens]
Length = 312
Score = 65.1 bits (157), Expect = 8e-11
Identities = 56/209 (26%), Positives = 94/209 (44%), Gaps = 13/209 (6%)
Query: 9 LISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDVC 68
+++G + GIG A +LA K +VV R K + + + E +D
Sbjct: 54 VVTGSTDGIGKSYAEELA---KHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFA 110
Query: 69 SDESVAQCLSCIQG-EVDVLVNNAGMGLVGPLEGLSLAAMQNVF----DTNFFGAVRLVK 123
S++ + + + G E+ +LVNN GM P L + + NV + N ++ +
Sbjct: 111 SEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQ 170
Query: 124 AVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFISLV 183
VLPGM R +G I+ ISS G+ V +Y+A+K ++ F + L + +F+ V
Sbjct: 171 LVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSV 230
Query: 184 EPGPVVTEFEGKLLAQVSMAEFPGTDPET 212
P V T+ LA++ PET
Sbjct: 231 LPYFVATK-----LAKIRKPTLDKPSPET 254
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,131,898
Number of Sequences: 37866
Number of extensions: 448630
Number of successful extensions: 1063
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 950
Number of HSP's gapped (non-prelim): 73
length of query: 311
length of database: 18,247,518
effective HSP length: 102
effective length of query: 209
effective length of database: 14,385,186
effective search space: 3006503874
effective search space used: 3006503874
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.