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Search of human proteins with 7657361
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657361 contactin 6 [Homo sapiens]
(1028 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657361 contactin 6 [Homo sapiens] 2078 0.0
gi|28373122 contactin 4 isoform a precursor [Homo sapiens] 1305 0.0
gi|75709184 contactin 3 [Homo sapiens] 1301 0.0
gi|28373129 contactin 5 isoform short [Homo sapiens] 1044 0.0
gi|7657359 contactin 5 isoform long [Homo sapiens] 1041 0.0
gi|28373126 contactin 4 isoform c precursor [Homo sapiens] 871 0.0
gi|4827022 contactin 2 precursor [Homo sapiens] 857 0.0
gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens] 821 0.0
gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens] 821 0.0
gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo... 384 e-106
gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo ... 379 e-105
gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo s... 379 e-105
gi|27894376 cell adhesion molecule with homology to L1CAM precur... 355 1e-97
gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 337 3e-92
gi|81158226 neuronal cell adhesion molecule isoform A precursor ... 333 4e-91
gi|237858679 neurofascin isoform 3 precursor [Homo sapiens] 319 7e-87
gi|89903008 neurofascin isoform 4 precursor [Homo sapiens] 319 7e-87
gi|237858677 neurofascin isoform 2 precursor [Homo sapiens] 311 2e-84
gi|222352127 sidekick 2 [Homo sapiens] 311 3e-84
gi|28373124 contactin 4 isoform b precursor [Homo sapiens] 300 4e-81
gi|237858675 neurofascin isoform 1 precursor [Homo sapiens] 298 2e-80
gi|119220552 sidekick 1 [Homo sapiens] 290 5e-78
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 213 7e-55
gi|237858682 neurofascin isoform 6 precursor [Homo sapiens] 198 2e-50
gi|237858680 neurofascin isoform 5 precursor [Homo sapiens] 198 2e-50
gi|19743806 roundabout 1 isoform b [Homo sapiens] 194 5e-49
gi|4506569 roundabout 1 isoform a [Homo sapiens] 194 5e-49
gi|110431348 deleted in colorectal carcinoma [Homo sapiens] 193 6e-49
gi|157311649 neogenin homolog 1 [Homo sapiens] 193 8e-49
gi|118572606 hemicentin 1 [Homo sapiens] 191 3e-48
>gi|7657361 contactin 6 [Homo sapiens]
Length = 1028
Score = 2078 bits (5384), Expect = 0.0
Identities = 1028/1028 (100%), Positives = 1028/1028 (100%)
Query: 1 MRLLWKLVILLPLINSSAGDGLLSRPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHY 60
MRLLWKLVILLPLINSSAGDGLLSRPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHY
Sbjct: 1 MRLLWKLVILLPLINSSAGDGLLSRPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHY 60
Query: 61 RWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAY 120
RWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAY
Sbjct: 61 RWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAY 120
Query: 121 IEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGN 180
IEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGN
Sbjct: 121 IEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGN 180
Query: 181 LYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAA 240
LYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAA
Sbjct: 181 LYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAA 240
Query: 241 KDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIAS 300
KDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIAS
Sbjct: 241 KDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIAS 300
Query: 301 NLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNP 360
NLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNP
Sbjct: 301 NLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNP 360
Query: 361 EERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSF 420
EERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSF
Sbjct: 361 EERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSF 420
Query: 421 VQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCI 480
VQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCI
Sbjct: 421 VQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCI 480
Query: 481 ATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGD 540
ATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGD
Sbjct: 481 ATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGD 540
Query: 541 VIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGP 600
VIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGP
Sbjct: 541 VIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGP 600
Query: 601 PEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNA 660
PEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNA
Sbjct: 601 PEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNA 660
Query: 661 TVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVIT 720
TVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVIT
Sbjct: 661 TVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVIT 720
Query: 721 WESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGV 780
WESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGV
Sbjct: 721 WESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGV 780
Query: 781 YNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEV 840
YNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEV
Sbjct: 781 YNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEV 840
Query: 841 LYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKK 900
LYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKK
Sbjct: 841 LYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKK 900
Query: 901 SPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSA 960
SPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSA
Sbjct: 901 SPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSA 960
Query: 961 ELLVPFEEDYLIEIRTVSDGGDGSSSEEIRIPKMSSLSSRGIQFLEPSTHFLSIVIVIFH 1020
ELLVPFEEDYLIEIRTVSDGGDGSSSEEIRIPKMSSLSSRGIQFLEPSTHFLSIVIVIFH
Sbjct: 961 ELLVPFEEDYLIEIRTVSDGGDGSSSEEIRIPKMSSLSSRGIQFLEPSTHFLSIVIVIFH 1020
Query: 1021 CFAIQPLI 1028
CFAIQPLI
Sbjct: 1021 CFAIQPLI 1028
>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
Length = 1026
Score = 1305 bits (3377), Expect = 0.0
Identities = 617/1002 (61%), Positives = 775/1002 (77%), Gaps = 4/1002 (0%)
Query: 1 MRLLWKLVILLPLINSSAGDGLLSRPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHY 60
MRL W+L++L I A D L PIF QEP V+FPLD + +V LNC G P PH
Sbjct: 1 MRLPWELLVLQSFILCLADDSTLHGPIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHI 60
Query: 61 RWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAY 120
RWK NGTD+D M + Y + GSL IN+P+ QD G YQC ATN GTI+SR+AKLQFAY
Sbjct: 61 RWKLNGTDVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAY 120
Query: 121 IEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGN 180
+++F+T+TRSTVSVR GQG+VLLCGPPPH G+LSYAW FN+ P Y +DNRRFVSQETGN
Sbjct: 121 LDNFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPSY--QDNRRFVSQETGN 178
Query: 181 LYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAA 240
LYIAKVE SDVGNYTC +TN V GPPTPL+ R DGVMGEYEPKIEV+FPET+ A
Sbjct: 179 LYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTA 238
Query: 241 KDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIAS 300
K ++VKLECFALGNPVP I WRR DG P+ K + KS ILEIPNFQQED G YEC+A
Sbjct: 239 KGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKSNGILEIPNFQQEDAGLYECVAE 298
Query: 301 NLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNP 360
N RG+N+A+GQL FYA P W QKI + H+++ +N+ WECKA+G+P P Y WLKNGE L
Sbjct: 299 NSRGKNVARGQLTFYAQPNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGEPLLT 358
Query: 361 EERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSF 420
+RIQIE GTL IT++N+SD+G+YQC AENK+ +I++NAEL V+A PDFS++ +K+ +
Sbjct: 359 RDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTL 418
Query: 421 VQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCI 480
V+VGG++VI CKP A P+ +WK+G + L++++RI + EDG+L+I N+T+SDAGSYTCI
Sbjct: 419 VKVGGEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCI 478
Query: 481 ATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGD 540
ATN FGTA +TG+L+VK+ T + VPPS MDVTVGESIVLPCQV+HD S+++VF W FNG
Sbjct: 479 ATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGH 538
Query: 541 VIDLKKGVAHFERIGG-ESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPG 599
+ID + HFER+GG +S GDLMIRNIQL H+GKY+C VQT+++ LSA AD+IVRGPPG
Sbjct: 539 LIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPG 598
Query: 600 PPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYN 659
PPE V +++I+ TT+QLSWR GPDN+SPI ++ IQ RTPFSVGWQAV+TVPE+++GKT+
Sbjct: 599 PPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFT 658
Query: 660 ATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVI 719
ATVVGL+PWVEYEFR VA N IGIGEPS PSE RT+ ++P V P N+ GGGGS+SELVI
Sbjct: 659 ATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVI 718
Query: 720 TWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVG 779
TWE++PEELQNG GFGY++ FRP G W ++S ++SR+V+RNES+ P SPFEVKVG
Sbjct: 719 TWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYVFRNESVHPFSPFEVKVG 778
Query: 780 VYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYE 839
V+NN+GEG S T+VYS E+EP P +S SA+++EV W A +N GR+ GYE
Sbjct: 779 VFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFW-ASPLEKNRGRIQGYE 837
Query: 840 VLYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTK 899
V YW + KE KIR GN T+ IT LK + +Y +V+AYN+AGTGPSS VNVTT+
Sbjct: 838 VKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTR 897
Query: 900 KSPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHILETNNTS 959
K PPSQPP NI W ++SK+ LNW+ VK ++NESEV GYK+LYR NRQS T ++ETN TS
Sbjct: 898 KPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTS 957
Query: 960 AELLVPFEEDYLIEIRTVSDGGDGSSSEEIRIPKMSSLSSRG 1001
EL +PF+EDY+IEI+ SDGGDGSSSE+IRIPK+S+ +RG
Sbjct: 958 VELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARG 999
>gi|75709184 contactin 3 [Homo sapiens]
Length = 1028
Score = 1301 bits (3366), Expect = 0.0
Identities = 608/1022 (59%), Positives = 789/1022 (77%), Gaps = 4/1022 (0%)
Query: 1 MRLLWKLVILLPLINSSAGDGLLSRPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHY 60
M WK +ILL I G+ LL P+F +EP + IFP+ ++ L+C A G PSPHY
Sbjct: 1 MMFPWKQLILLSFIGCLGGELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHY 60
Query: 61 RWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAY 120
RW+ NG+DID +M + Y+L+GG+L + +P+ + D G YQC ATN LGTI+SR+AKLQFAY
Sbjct: 61 RWQLNGSDIDMSMEHRYKLNGGNLVVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAY 120
Query: 121 IEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGN 180
+E+F+TK RSTVSVREGQGVVLLCGPPPH G+LSYAW FN+ P +V+ED+RRFVSQETG+
Sbjct: 121 LENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGH 180
Query: 181 LYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAA 240
LYI+KVEPSDVGNYTC +T+ V G PTPLV R+DGVMGEYEPKIEV+FPET+ AA
Sbjct: 181 LYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAA 240
Query: 241 KDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIAS 300
K S+VKLECFALGNP+P I+WRR DG P K+K K +LEIPNFQQED G YECIA
Sbjct: 241 KGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAE 300
Query: 301 NLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNP 360
N RG+N+A+G+L +YA P W Q I++ +++ D+L WEC+ASGKP P Y WLKNG L
Sbjct: 301 NSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVL 360
Query: 361 EERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSF 420
EER QIENG L I+ L+V+DSG++QC AENK+ ++Y++AEL+V+ASAPDFSK+P+KK
Sbjct: 361 EERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQ 420
Query: 421 VQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCI 480
VQVG + + CKP A PRA SWK+G ++++ +RI LL DG LKI N+T++DAG+YTC+
Sbjct: 421 VQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCM 480
Query: 481 ATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGD 540
A NQFG A T L+V E T IT+ PS MDV+VGES++LPCQV HDP ++++F W+FNG
Sbjct: 481 AENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGA 540
Query: 541 VIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGP 600
+ D KK +HFE++GG S GDLMIRNIQL HSGKY+C VQT ++S+S+ AD+IVRG PGP
Sbjct: 541 LADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGP 600
Query: 601 PEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNA 660
PE+V+V++I+ TT+QLSW+ G DN+SP+ ++IQ RTPFSVGWQ V TVPE+++GKT+ A
Sbjct: 601 PENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTA 660
Query: 661 TVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVIT 720
TVV L+PWVEYEFRVVA N IG GEPS PSE +RT+ +VP V P ++GGGGSRSELVIT
Sbjct: 661 TVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVIT 720
Query: 721 WESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGV 780
W+ +PEELQNGEGFGY++ FRP+G TTW + V+S ++ R+V+RNESI+P SP+EVKVGV
Sbjct: 721 WDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGV 780
Query: 781 YNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEV 840
YNN+GEG S VT V+S E+EP +AP S S S+SE+EVSWN I W + G +LGYEV
Sbjct: 781 YNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEV 840
Query: 841 LYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKK 900
YW KE K++V+GN T+ + GLK+N Y+ +VRAYN+AG GP S VNVTTKK
Sbjct: 841 RYWNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKK 900
Query: 901 SPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSA 960
+PPSQPP N+ W T++K+ LNWE VK MENESEV GYK+ YR + Q+ +L TN TSA
Sbjct: 901 TPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSA 960
Query: 961 ELLVPFEEDYLIEIRTVSDGGDGSSSEEIRIPKMSSLSSRG----IQFLEPSTHFLSIVI 1016
EL++P +EDY+IE++ +DGGDG+SSE+IRIP+++S+ +RG I + P + ++ IV+
Sbjct: 961 ELVLPIKEDYIIEVKATTDGGDGTSSEQIRIPRITSMDARGSTSAISNVHPMSSYMPIVL 1020
Query: 1017 VI 1018
+
Sbjct: 1021 FL 1022
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 1044 bits (2700), Expect = 0.0
Identities = 515/1010 (50%), Positives = 680/1010 (67%), Gaps = 8/1010 (0%)
Query: 5 WKLVILLPLINSSAGDGLLSRPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQ 64
WKL++ L + + + P+F QEP D+IFP D + +V LNC G P P YRW +
Sbjct: 5 WKLMLFLS-VTMCLSESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLR 63
Query: 65 NGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDF 124
NGT+ID Y Y L G+ I++P +D G YQCLATN +G+ILSR+A LQFAY+ +F
Sbjct: 64 NGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQCLATNTVGSILSREATLQFAYLGNF 123
Query: 125 ETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIA 184
+TRS VSVREGQGVVL+C PPPH ++ Y+W FN+ P +V ED+RRF+SQETGNLYI+
Sbjct: 124 SGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYIS 183
Query: 185 KVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSS 244
KV+ SDVG+Y C + N V PPTPL R DGVMGEYEPKIEV FP T+ AAK ++
Sbjct: 184 KVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTT 243
Query: 245 VKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRG 304
VK+ECFALGNPVP I+W +++G +P K + KSQA+LEIPN Q +D G YEC A N RG
Sbjct: 244 VKMECFALGNPVPTITWMKVNGY-IPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRG 302
Query: 305 RNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERI 364
+N +GQL Y P W +K+ +T L L WECKA+GKP P Y WLKNG L+P+ R+
Sbjct: 303 KNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRV 362
Query: 365 QIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVG 424
++ NG L+I +N SD+G+YQC AENKY IYA+AEL++LASAP F+ + +KK V
Sbjct: 363 EMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKD 422
Query: 425 GDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQ 484
++VI CKP P+ ISWK+G +R++KRI +L DGSL+I N ++SD G Y C N
Sbjct: 423 QEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENV 482
Query: 485 FGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDL 544
FG+A+ SL VKE T I + P + ++TVGESIVL C+ HD S++V F W G ID
Sbjct: 483 FGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDF 542
Query: 545 KKGVAHFERIGGE-SVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPED 603
++ HFE I + S DLMIRNI L H+G+Y C VQTT +S+S A+++VRGPPGPP
Sbjct: 543 EEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGI 602
Query: 604 VQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNATVV 663
V VE+I+ +T+ LSW DN+SPI + +Q R+PFS+GWQ V TVPEI+ G +A V
Sbjct: 603 VIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAV 662
Query: 664 GLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWES 723
L+PWVEYEFRVVA N IG G+PS PS ++RT +VP AP N+ G G R ELVI WE
Sbjct: 663 DLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEP 722
Query: 724 IPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNN 783
+ EE QNGEGFGYI+ FRP G+ W ++ V+S E+S+F+YR+ES+ PL+PFEVKVGVYNN
Sbjct: 723 VSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNN 782
Query: 784 EGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYW 843
+G+G S + ++ S E EP AP S S SE+ V+W I + GR G+EV YW
Sbjct: 783 KGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHI--KESLGRPQGFEVGYW 840
Query: 844 TDDSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPP 903
D +E ++ GN + +TGL+ NT+Y +VRAYN AG GP S V+ TTKKSPP
Sbjct: 841 KDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPP 900
Query: 904 SQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSAELL 963
SQ P+N+ W+ S++ L WE V + NESEV+GYK+ YRQ S + ++ET A +
Sbjct: 901 SQAPSNLRWEQQGSQVSLGWEPVIPLANESEVVGYKVFYRQEGHSNSQVIETQKLQAVVP 960
Query: 964 VPFEEDYLIEIRTVSDGGDGSSSEEIRIPKMSSLSSRGIQFLEPSTHFLS 1013
+P Y+IE+R S+GGDG++S +IR+P S S I + + H LS
Sbjct: 961 LPDAGVYIIEVRAYSEGGDGTASSQIRVP---SYSGGKITSAQSTLHSLS 1007
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 1041 bits (2691), Expect = 0.0
Identities = 511/989 (51%), Positives = 671/989 (67%), Gaps = 7/989 (0%)
Query: 26 PIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLA 85
P+F QEP D+IFP D + +V LNC G P P YRW +NGT+ID Y Y L G+
Sbjct: 99 PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFI 158
Query: 86 INSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCG 145
I++P +D G YQCLATN +G+ILSR+A LQFAY+ +F +TRS VSVREGQGVVL+C
Sbjct: 159 ISNPSEAKDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCS 218
Query: 146 PPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQR 205
PPPH ++ Y+W FN+ P +V ED+RRF+SQETGNLYI+KV+ SDVG+Y C + N
Sbjct: 219 PPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNA 278
Query: 206 SVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLD 265
V PPTPL R DGVMGEYEPKIEV FP T+ AAK ++VK+ECFALGNPVP I+W +++
Sbjct: 279 RVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVN 338
Query: 266 GSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQ 325
G +P K + KSQA+LEIPN Q +D G YEC A N RG+N +GQL Y P W +K+
Sbjct: 339 GY-IPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLN 397
Query: 326 NTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQIENGTLIITMLNVSDSGVYQ 385
+T L L WECKA+GKP P Y WLKNG L+P+ R+++ NG L+I +N SD+G+YQ
Sbjct: 398 DTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQ 457
Query: 386 CAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKR 445
C AENKY IYA+AEL++LASAP F+ + +KK V ++VI CKP P+ ISWK+
Sbjct: 458 CLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKK 517
Query: 446 GTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVP 505
G +R++KRI +L DGSL+I N ++SD G Y C N FG+A+ SL VKE T I +
Sbjct: 518 GDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELT 577
Query: 506 PSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGE-SVGDLMI 564
P + ++TVGESIVL C+ HD S++V F W G ID ++ HFE I + S DLMI
Sbjct: 578 PKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMI 637
Query: 565 RNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDN 624
RNI L H+G+Y C VQTT +S+S A+++VRGPPGPP V VE+I+ +T+ LSW DN
Sbjct: 638 RNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITESTATLSWSPAADN 697
Query: 625 NSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIG 684
+SPI + +Q R+PFS+GWQ V TVPEI+ G +A V L+PWVEYEFRVVA N IG G
Sbjct: 698 HSPISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRVVATNPIGTG 757
Query: 685 EPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVG 744
+PS PS ++RT +VP AP N+ G G R ELVI WE + EE QNGEGFGYI+ FRP G
Sbjct: 758 DPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNG 817
Query: 745 STTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQL 804
+ W ++ V+S E+S+F+YR+ES+ PL+PFEVKVGVYNN+G+G S + ++ S E EP
Sbjct: 818 TRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSA 877
Query: 805 APRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTK 864
AP S S SE+ V+W I + GR G+EV YW D +E ++ GN +
Sbjct: 878 APTDVKATSVSVSEILVAWKHI--KESLGRPQGFEVGYWKDMEQEDTAETVKTRGNESFV 935
Query: 865 NITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWE 924
+TGL+ NT+Y +VRAYN AG GP S V+ TTKKSPPSQ P+N+ W+ S++ L WE
Sbjct: 936 ILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRWEQQGSQVSLGWE 995
Query: 925 HVKTMENESEVLGYKILYRQNRQSKTHILETNNTSAELLVPFEEDYLIEIRTVSDGGDGS 984
V + NESEV+GYK+ YRQ S + ++ET A + +P Y+IE+R S+GGDG+
Sbjct: 996 PVIPLANESEVVGYKVFYRQEGHSNSQVIETQKLQAVVPLPDAGVYIIEVRAYSEGGDGT 1055
Query: 985 SSEEIRIPKMSSLSSRGIQFLEPSTHFLS 1013
+S +IR+P S S I + + H LS
Sbjct: 1056 ASSQIRVP---SYSGGKITSAQSTLHSLS 1081
>gi|28373126 contactin 4 isoform c precursor [Homo sapiens]
Length = 698
Score = 871 bits (2250), Expect = 0.0
Identities = 407/670 (60%), Positives = 527/670 (78%), Gaps = 2/670 (0%)
Query: 333 DNLLWECKASGKPNPWYTWLKNGERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKY 392
+N+ WECKA+G+P P Y WLKNGE L +RIQIE GTL IT++N+SD+G+YQC AENK+
Sbjct: 3 ENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKH 62
Query: 393 QIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQ 452
+I++NAEL V+A PDFS++ +K+ + V+VGG++VI CKP A P+ +WK+G + L++
Sbjct: 63 GVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKE 122
Query: 453 SKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVT 512
++RI + EDG+L+I N+T+SDAGSYTCIATN FGTA +TG+L+VK+ T + VPPS MDVT
Sbjct: 123 NERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVT 182
Query: 513 VGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGE-SVGDLMIRNIQLHH 571
VGESIVLPCQV+HD S+++VF W FNG +ID + HFER+GG+ S GDLMIRNIQL H
Sbjct: 183 VGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKH 242
Query: 572 SGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIF 631
+GKY+C VQT+++ LSA AD+IVRGPPGPPE V +++I+ TT+QLSWR GPDN+SPI ++
Sbjct: 243 AGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMY 302
Query: 632 TIQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSE 691
IQ RTPFSVGWQAV+TVPE+++GKT+ ATVVGL+PWVEYEFR VA N IGIGEPS PSE
Sbjct: 303 VIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSE 362
Query: 692 LLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKE 751
RT+ ++P V P N+ GGGGS+SELVITWE++PEELQNG GFGY++ FRP G W
Sbjct: 363 KRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLT 422
Query: 752 KVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSL 811
++S ++SR+V+RNES+ P SPFEVKVGV+NN+GEG S T+VYS E+EP P
Sbjct: 423 VLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFA 482
Query: 812 QSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTKNITGLKA 871
+S SA+++EV W A +N GR+ GYEV YW + KE KIR GN T+ IT LK
Sbjct: 483 RSLSATDIEVFW-ASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKG 541
Query: 872 NTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTMEN 931
+ +Y +V+AYN+AGTGPSS VNVTT+K PPSQPP NI W ++SK+ LNW+ VK ++N
Sbjct: 542 SVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDN 601
Query: 932 ESEVLGYKILYRQNRQSKTHILETNNTSAELLVPFEEDYLIEIRTVSDGGDGSSSEEIRI 991
ESEV GYK+LYR NRQS T ++ETN TS EL +PF+EDY+IEI+ SDGGDGSSSE+IRI
Sbjct: 602 ESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRI 661
Query: 992 PKMSSLSSRG 1001
PK+S+ +RG
Sbjct: 662 PKISNAYARG 671
Score = 119 bits (297), Expect = 2e-26
Identities = 163/700 (23%), Positives = 270/700 (38%), Gaps = 85/700 (12%)
Query: 242 DSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASN 301
+ +V EC A G P P W + +G PL + + Q L I D G Y+C+A N
Sbjct: 2 EENVFWECKANGRPKPTYKWLK-NGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAEN 60
Query: 302 LRGRNLAKGQL-IFYAPPEWEQKIQN--THLSIYDNLLWECKASGKPNPWYTWLKNGERL 358
G + +L + P++ + + T + + ++ ECK P P YTW K + L
Sbjct: 61 KHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDIL 120
Query: 359 NPEERIQI-ENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKK 417
ERI I E+G L I + SD+G Y C A N + + L V D ++ V
Sbjct: 121 KENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVV----KDPTRVMVPP 176
Query: 418 KSF-VQVGGDIVIGCKPN-----------AFPRAAISWKRGTETLRQSKRIFLLED-GSL 464
S V VG IV+ C+ +F I + R + +R+ + G L
Sbjct: 177 SSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGD---HFERVGGQDSAGDL 233
Query: 465 KIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMD-VTVGESIVLPCQV 523
I NI AG Y C+ LIV+ PP + VT+ E Q+
Sbjct: 234 MIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRG------PPGPPEAVTIDEITDTTAQL 287
Query: 524 SHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTL 583
S P + N I + A SVG + + GK L
Sbjct: 288 SWRPGPD-------NHSPITMYVIQARTP----FSVGWQAVSTVPELIDGKTFTATVVGL 336
Query: 584 ------ESLSAVADIIVRGPPG-PPEDVQVEDISSTTSQLSWRAGPDNNSPIQI------ 630
E + A++I G P P E + E+ + + G + S + I
Sbjct: 337 NPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVP 396
Query: 631 ----------FTIQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNS 680
+ + R + W + TV + Y + P+ +E +V N+
Sbjct: 397 EELQNGRGFGYVVAFRPYGKMIW--MLTVLASADASRYVFRNESVHPFSPFEVKVGVFNN 454
Query: 681 IGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMF 740
G G P P+ ++ + P P +I S +++ + W S P E G GY + +
Sbjct: 455 KGEG-PFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWAS-PLEKNRGRIQGYEVKY 512
Query: 741 RPVGSTTWSKEKVSSV---ESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYS 797
+ K+ +V S++ S++ + + V YN+ G G S+ T+ +
Sbjct: 513 WRHEDKEENARKIRTVGNQTSTKITNLKGSVL----YHLAVKAYNSAGTGP-SSATVNVT 567
Query: 798 GEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLY-WTDDSKESMIGKIR 856
P P G + + S S++ ++W+ + N V GY+VLY W S S+I +
Sbjct: 568 TRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNK 627
Query: 857 VSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNV 896
S ++ L + Y ++ ++ G G SS + +
Sbjct: 628 TSVELS------LPFDEDYIIEIKPFSDGGDGSSSEQIRI 661
Score = 80.5 bits (197), Expect = 8e-15
Identities = 82/287 (28%), Positives = 111/287 (38%), Gaps = 30/287 (10%)
Query: 43 KSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLA 102
+ V C ANG P P Y+W +NG + +++ G+L I + D GMYQCLA
Sbjct: 2 EENVFWECKANGRPKPTYKWLKNGEPL--LTRDRIQIEQGTLNITIVNLS-DAGMYQCLA 58
Query: 103 TNLLGTILSRKAKLQFAYIEDFE-TKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFND 161
N G I S A DF T + V+ G VV+ C P + Y W
Sbjct: 59 ENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPV-YTWKKGR 117
Query: 162 NPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGV 221
+ L ++N R E GNL I V SD G+YTC TN S + G
Sbjct: 118 DIL---KENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTAS-----------STGN 163
Query: 222 MGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDI--SWR--------RLDGSPLPG 271
+ +P + P ++ S+ L C + DI +W DG
Sbjct: 164 LVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFE- 222
Query: 272 KVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPP 318
+V S L I N Q + G Y C+ R A LI PP
Sbjct: 223 RVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPP 269
>gi|4827022 contactin 2 precursor [Homo sapiens]
Length = 1040
Score = 857 bits (2213), Expect = 0.0
Identities = 437/1003 (43%), Positives = 608/1003 (60%), Gaps = 40/1003 (3%)
Query: 7 LVILLPLINSSAGDGLLSR-----PIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYR 61
LV + L++SSA L P+F +P V+FP + ++ +V+L C A P YR
Sbjct: 13 LVAAVALVSSSAWSSALGSQTTFGPVFEDQPLSVLFPEESTEEQVLLACRARASPPATYR 72
Query: 62 WKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYI 121
WK NGT++ ++L GG+L I +P QD G+YQCLA+N +GT++SR+A L+F ++
Sbjct: 73 WKMNGTEMKLEPGSRHQLVGGNLVIMNPTKAQDAGVYQCLASNPVGTVVSREAILRFGFL 132
Query: 122 EDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNL 181
++F + R V EG GV+L C PP H+ LSY W N+ P ++ D R FVSQ TGNL
Sbjct: 133 QEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNL 192
Query: 182 YIAKVEPSDVGNYTCFITN-----------KEAQRSVQGPPTPLVQRTDGVMGEYEPKIE 230
YIA+ SD+GNY+C T+ K AQ ++ T L + P I+
Sbjct: 193 YIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAAEDTRL----------FAPSIK 242
Query: 231 VRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQE 290
RFP A V LECFA GNPVP I WR++DGS P +++ ++ L+IP+ E
Sbjct: 243 ARFPAETYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSP---QWTTAEPTLQIPSVSFE 299
Query: 291 DEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYT 350
DEG YEC A N +GR+ +G++I A PEW + I +T I NL W C A+GKP P
Sbjct: 300 DEGTYECEAENSKGRDTVQGRIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVR 359
Query: 351 WLKNGERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDF 410
WL+NGE L + R+++ G L + L++ DSG+YQC AENK+ IYA+AEL V A APDF
Sbjct: 360 WLRNGEPLASQNRVEVLAGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDF 419
Query: 411 SKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNIT 470
+PV++ GG+I+I C+P A P+A + W +GTE L S R+ + DG+L I NI+
Sbjct: 420 RLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNIS 479
Query: 471 RSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIE 530
RSD G YTC A N G A +TG L V++ T IT+ PS D+ +G+++ L C SHDP+++
Sbjct: 480 RSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMD 539
Query: 531 VVFVWFFNGDVIDLKKGVAHFERIG-GESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAV 589
+ F W + ID K H+ R E++GDL I N QL H GKY C QT ++S S
Sbjct: 540 LTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKE 599
Query: 590 ADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATV 649
A ++VRGPPGPP V V DI TT QLSW G DN+SPI +T+Q RTP + W+ V T
Sbjct: 600 ATVLVRGPPGPPGGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTN 659
Query: 650 PEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHG 709
P + G A V+GL+PW++YEFRV+A N +G GEPS PS +RT+ + P VAP + G
Sbjct: 660 PANIEGNAETAQVLGLTPWMDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSG 719
Query: 710 GGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESII 769
GGG+ EL++ W + E QNG+GFGY++ FR GST W +V ++ FVY NES+
Sbjct: 720 GGGAPGELIVNWTPMSREYQNGDGFGYLLSFRRQGSTHWQTARVPGADAQYFVYSNESVR 779
Query: 770 PLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWN 829
P +PFEVK+ YN G+G S +VYS E+EP++AP + S+SEM V+W + +
Sbjct: 780 PYTPFEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQQD 839
Query: 830 RNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGP 889
N G +LGYE+ YW KE+ ++R +G T+ ++GL NT Y +VRAYN AGTGP
Sbjct: 840 MN-GILLGYEIRYWKAGDKEAAADRVRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTGP 898
Query: 890 SSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSK 949
+SP N TT K PP +PP NI+W ++S L + W+ V NES V GYK+LY Q+
Sbjct: 899 ASPSANATTMKPPPRRPPGNISWTFSSSSLSIKWDPVVPFRNESAVTGYKMLY----QND 954
Query: 950 THILETNNTSAE--LLVPFEEDY---LIEIRTVSDGGDGSSSE 987
H+ T + + + + +P ED L++IRT GGDG +E
Sbjct: 955 LHLTPTLHLTGKNWIEIPVPEDIGHALVQIRTTGPGGDGIPAE 997
>gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]
Length = 1018
Score = 821 bits (2120), Expect = 0.0
Identities = 421/985 (42%), Positives = 599/985 (60%), Gaps = 18/985 (1%)
Query: 26 PIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLA 85
PIF ++P + I+P + + +V LNC A P P Y+W+ N D+D T S Y + GG+L
Sbjct: 41 PIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLT-SDRYSMVGGNLV 99
Query: 86 INSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCG 145
IN+P +D G+Y CLA+N G + S +A L F Y++ F + R V V+EG+G+VLLC
Sbjct: 100 INNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCD 159
Query: 146 PPPHF-GDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQ 204
PP HF DLSY W N+ P+++ D RRFVSQ GNLYIA VE SD GNY+CF+++
Sbjct: 160 PPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSIT 219
Query: 205 RSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRL 264
+SV PL+ + Y I V+F + + A +V LECFALGNPVPDI WR++
Sbjct: 220 KSVFSKFIPLIPIPERTTKPYPADIVVQFKD-VYALMGQNVTLECFALGNPVPDIRWRKV 278
Query: 265 DGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKI 324
P+P + S S A+L+I N Q EDEG YEC A N+RG++ + ++ A PEW + I
Sbjct: 279 L-EPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHI 337
Query: 325 QNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQIENGTLIITMLNVSDSGVY 384
+T + I +L W C A+GKP P WLKNG + G L + + ++G+Y
Sbjct: 338 NDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYH--------KGELRLYDVTFENAGMY 389
Query: 385 QCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWK 444
QC AEN Y IYANAEL++LA AP F +P+KKK GG ++I CKP A P+ SW
Sbjct: 390 QCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWS 449
Query: 445 RGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITV 504
+GTE L S RI + EDGSL+I NITR+D G YTC A N G A +TG+L++ + T I +
Sbjct: 450 KGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIIL 509
Query: 505 PPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFER-IGGESVGDLM 563
P D+TVGE+ + C S DP++++ FVW FNG VID K H++R +S G+L+
Sbjct: 510 APINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELL 569
Query: 564 IRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPD 623
IRN QL H+G+Y CT QT +++ SA AD++VRGPPGPP +++EDI +T+ L+W G D
Sbjct: 570 IRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALTWSRGSD 629
Query: 624 NNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGI 683
N+SPI +TIQT+T S W+ T P I+ G A V L PW+EYEFRVVA N++G
Sbjct: 630 NHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGR 689
Query: 684 GEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPV 743
GEPS PS ++T + P VAP ++ GGGG EL ITW + E G FGYI+ F+P
Sbjct: 690 GEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPF 749
Query: 744 GSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQ 803
W K V++ ++ R+V+++E++ P + F+VKV +NN+G+G S V ++ S +D P
Sbjct: 750 DGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPS 809
Query: 804 LAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTT 863
AP ++ S+SE+ V W + V Y++ YW KE +++V+ +
Sbjct: 810 EAPTEVGVKVLSSSEISVHWEHVL----EKIVESYQIRYWAAHDKEEAANRVQVTSQEYS 865
Query: 864 KNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNW 923
+ L +T YF V A N+AG GP S + TKK+PPSQPP I+ + S+ + W
Sbjct: 866 ARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITW 925
Query: 924 EHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSAELLVPFEEDYLIEIRTVSDGGDG 983
+HV + NES V GYK+LYR + Q + T+ S E+ +P + +Y++E+R SDGGDG
Sbjct: 926 DHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDGGDG 985
Query: 984 SSSEEIRIPKMSSLSSRGIQFLEPS 1008
S +++I +LS + L P+
Sbjct: 986 VVS-QVKISGAPTLSPSLLGLLLPA 1009
>gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens]
Length = 1007
Score = 821 bits (2120), Expect = 0.0
Identities = 421/985 (42%), Positives = 599/985 (60%), Gaps = 18/985 (1%)
Query: 26 PIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLA 85
PIF ++P + I+P + + +V LNC A P P Y+W+ N D+D T S Y + GG+L
Sbjct: 30 PIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLT-SDRYSMVGGNLV 88
Query: 86 INSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCG 145
IN+P +D G+Y CLA+N G + S +A L F Y++ F + R V V+EG+G+VLLC
Sbjct: 89 INNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCD 148
Query: 146 PPPHF-GDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQ 204
PP HF DLSY W N+ P+++ D RRFVSQ GNLYIA VE SD GNY+CF+++
Sbjct: 149 PPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSIT 208
Query: 205 RSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRL 264
+SV PL+ + Y I V+F + + A +V LECFALGNPVPDI WR++
Sbjct: 209 KSVFSKFIPLIPIPERTTKPYPADIVVQFKD-VYALMGQNVTLECFALGNPVPDIRWRKV 267
Query: 265 DGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKI 324
P+P + S S A+L+I N Q EDEG YEC A N+RG++ + ++ A PEW + I
Sbjct: 268 L-EPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHI 326
Query: 325 QNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQIENGTLIITMLNVSDSGVY 384
+T + I +L W C A+GKP P WLKNG + G L + + ++G+Y
Sbjct: 327 NDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYH--------KGELRLYDVTFENAGMY 378
Query: 385 QCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWK 444
QC AEN Y IYANAEL++LA AP F +P+KKK GG ++I CKP A P+ SW
Sbjct: 379 QCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWS 438
Query: 445 RGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITV 504
+GTE L S RI + EDGSL+I NITR+D G YTC A N G A +TG+L++ + T I +
Sbjct: 439 KGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIIL 498
Query: 505 PPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFER-IGGESVGDLM 563
P D+TVGE+ + C S DP++++ FVW FNG VID K H++R +S G+L+
Sbjct: 499 APINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELL 558
Query: 564 IRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPD 623
IRN QL H+G+Y CT QT +++ SA AD++VRGPPGPP +++EDI +T+ L+W G D
Sbjct: 559 IRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALTWSRGSD 618
Query: 624 NNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGI 683
N+SPI +TIQT+T S W+ T P I+ G A V L PW+EYEFRVVA N++G
Sbjct: 619 NHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGR 678
Query: 684 GEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPV 743
GEPS PS ++T + P VAP ++ GGGG EL ITW + E G FGYI+ F+P
Sbjct: 679 GEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPF 738
Query: 744 GSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQ 803
W K V++ ++ R+V+++E++ P + F+VKV +NN+G+G S V ++ S +D P
Sbjct: 739 DGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPS 798
Query: 804 LAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTT 863
AP ++ S+SE+ V W + V Y++ YW KE +++V+ +
Sbjct: 799 EAPTEVGVKVLSSSEISVHWEHVL----EKIVESYQIRYWAAHDKEEAANRVQVTSQEYS 854
Query: 864 KNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNW 923
+ L +T YF V A N+AG GP S + TKK+PPSQPP I+ + S+ + W
Sbjct: 855 ARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITW 914
Query: 924 EHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSAELLVPFEEDYLIEIRTVSDGGDG 983
+HV + NES V GYK+LYR + Q + T+ S E+ +P + +Y++E+R SDGGDG
Sbjct: 915 DHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDGGDG 974
Query: 984 SSSEEIRIPKMSSLSSRGIQFLEPS 1008
S +++I +LS + L P+
Sbjct: 975 VVS-QVKISGAPTLSPSLLGLLLPA 998
>gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo
sapiens]
Length = 1248
Score = 384 bits (985), Expect = e-106
Identities = 281/972 (28%), Positives = 452/972 (46%), Gaps = 56/972 (5%)
Query: 1 MRLLWKLVILLPLINSSAGDGLLSRPIFTQEPHD--VIFPLDLSKSEVILNCAANGYPSP 58
+R +W L++ P + + L+ P+ T++ V+FP D ++ L C A+G P
Sbjct: 5 LRYVWPLLLCSPCLLIQIPEELMEPPVITEQSPRRLVVFPTD----DISLKCEASGKPEV 60
Query: 59 HYRWKQNGTDI----DFTMSYHYRLDGGSLAI---NSPHTDQDIGMYQCLATNLLGTILS 111
+RW ++G + ++ + GS I NS + G+Y+C A+N LGT +S
Sbjct: 61 QFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMS 120
Query: 112 RKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNR 171
+ +L + +T V V EG+ VVL C PPP L W N L++++D R
Sbjct: 121 HEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYW-MNSKILHIKQDER 179
Query: 172 RFVSQETGNLYIAKVEPSDV-GNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIE 230
+ Q GNLY A V SD +Y C + +Q P L + M + +P++
Sbjct: 180 VTMGQN-GNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL- 237
Query: 231 VRFPET----IQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPN 286
FP + A + + LEC A G P P I W R G +V Y L++
Sbjct: 238 -LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLK 296
Query: 287 FQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPN 346
+ED+G Y C+A N G + A P W K Q+ + +C+ G+P
Sbjct: 297 VGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQ 356
Query: 347 PWYTWLKNG---ERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRV 403
P TW NG E L +++ +I+ G LI++ + SD+ V QC A N++ ++ ANA + V
Sbjct: 357 PEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 416
Query: 404 LASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISW--KRGTETLRQSKRIFLLED 461
+ + + VQ G + CK P ++ W + GT T+ Q +R F +
Sbjct: 417 VQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT-TVLQDERFFPYAN 474
Query: 462 GSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPC 521
G+L I ++ +D G Y C+A N +L VK+ T IT P G + C
Sbjct: 475 GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTC 534
Query: 522 QVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQT 581
Q S DPS++ W GD DL++ + ++ E G L+I ++ G Y C T
Sbjct: 535 QASFDPSLQPSITW--RGDGRDLQE-LGDSDKYFIED-GRLVIHSLDYSDQGNYSCVAST 590
Query: 582 TLESLSAVADIIVRGPPGPPEDVQVEDISSTTS---QLSWRAGPDNNSPIQIFTI--QTR 636
L+ + + A ++V G PGP + + D+ T ++SW D+N+PI+ + I + +
Sbjct: 591 ELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDK 650
Query: 637 TPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTK 696
W ++ VP +T + LSP+V Y FRV A N G GEPS SE + T
Sbjct: 651 EMAPEKWYSLGKVP-----GNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTP 705
Query: 697 ASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSV 756
+ P PV++ G G + +VITW+ + N Y + +RP G+ +E++ V
Sbjct: 706 EAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQI--V 763
Query: 757 ESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSA 816
V N S P+E+KV N++G+G VTI YSGED PQ P ++ ++
Sbjct: 764 SDPFLVVSNTS--TFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNS 821
Query: 817 SEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGK------IRVSGNVTTKNITGLK 870
S + V W + + G + GY V YW + S+ + + V N T+ ++GL+
Sbjct: 822 SAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLR 881
Query: 871 ANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTME 930
+ Y V+A+N G+GP+S +T + P P A +N+ L L W+ +
Sbjct: 882 PYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQ--PPLS 938
Query: 931 NESEVLGYKILY 942
+ + GY + Y
Sbjct: 939 HNGVLTGYVLSY 950
Score = 82.4 bits (202), Expect = 2e-15
Identities = 141/684 (20%), Positives = 265/684 (38%), Gaps = 66/684 (9%)
Query: 335 LLWECKASGKPNPWYTWLKNGERLNPEERIQIENGTLIITMLNVS--DSGVYQCAAENKY 392
L+ EC A G P P WL+ + P +R+ +N + +L V D G Y+C AEN
Sbjct: 255 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 313
Query: 393 QIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRG---TET 449
+A + +AP + P + G + C+ P+ ++W+ E
Sbjct: 314 GSA-RHAYYVTVEAAPYWLHKP--QSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEE 370
Query: 450 LRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKE--RTVITVPPS 507
L + ++ + ++ G+L + N+ SD C A N+ G + V + ++T
Sbjct: 371 LAKDQK-YRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQ 429
Query: 508 KMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNI 567
G + L C+ P V W L+ ER + G L IR++
Sbjct: 430 TYMAVQGSTAYLLCKAFGAPVPSVQ--WLDEDGTTVLQD-----ERFFPYANGTLGIRDL 482
Query: 568 QLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSP 627
Q + +G+Y C +++ +A++ V+ + + I S++++ +
Sbjct: 483 QANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPR-STIEKKGSRVTFTCQASFDPS 541
Query: 628 IQIFTIQTRTPFSVGWQAVAT-VPEILNGKTY-----NATVVGLSPWVEYEFRVVAGNSI 681
+Q S+ W+ + E+ + Y + L + + VA +
Sbjct: 542 LQP---------SITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 592
Query: 682 GIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMF- 740
+ E ++ + VP + ++H ++S++ ++W P E N Y I F
Sbjct: 593 DVVESRAQLLVVGSPGPVPRLVLSDLHLL--TQSQVRVSWS--PAEDHNAPIEKYDIEFE 648
Query: 741 -RPVGSTTW-SKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVT-IVYS 797
+ + W S KV ++S + + P + +V N G G S V+ V +
Sbjct: 649 DKEMAPEKWYSLGKVPGNQTSTTL----KLSPYVHYTFRVTAINKYGPGEPSPVSETVVT 704
Query: 798 GEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRV 857
E P+ P + + M ++W + W + Y V + ++ +I
Sbjct: 705 PEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVS 764
Query: 858 SGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNV--TTKKSPPSQPPANIAWKLT 915
+ N + Y V+A N+ G GP P V + + + P + P L
Sbjct: 765 DPFLVVSNTSTFVP---YEIKVQAVNSQGKGPE-PQVTIGYSGEDYPQAIPELEGIEILN 820
Query: 916 NSKLCLNWEHVKTMENESEVLGYKILY----RQNRQSKTHI------LETNNTSAEL--L 963
+S + + W V + + + GY + Y Q + SK HI + N TS L L
Sbjct: 821 SSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGL 880
Query: 964 VPFEEDYLIEIRTVSDGGDGSSSE 987
P+ Y +E++ + G G +SE
Sbjct: 881 RPY-SSYHLEVQAFNGRGSGPASE 903
>gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 1253
Score = 379 bits (974), Expect = e-105
Identities = 281/977 (28%), Positives = 452/977 (46%), Gaps = 61/977 (6%)
Query: 1 MRLLWKLVILLPLI-----NSSAGDGLLSRPIFTQEPHD--VIFPLDLSKSEVILNCAAN 53
+R +W L++ P + G ++ P+ T++ V+FP D ++ L C A+
Sbjct: 5 LRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTD----DISLKCEAS 60
Query: 54 GYPSPHYRWKQNGTDI----DFTMSYHYRLDGGSLAI---NSPHTDQDIGMYQCLATNLL 106
G P +RW ++G + ++ + GS I NS + G+Y+C A+N L
Sbjct: 61 GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL 120
Query: 107 GTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYV 166
GT +S + +L + +T V V EG+ VVL C PPP L W N L++
Sbjct: 121 GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYW-MNSKILHI 179
Query: 167 QEDNRRFVSQETGNLYIAKVEPSDV-GNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEY 225
++D R + Q GNLY A V SD +Y C + +Q P L + M +
Sbjct: 180 KQDERVTMGQN-GNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDR 238
Query: 226 EPKIEVRFPET----IQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAI 281
+P++ FP + A + + LEC A G P P I W R G +V Y
Sbjct: 239 KPRL--LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKT 296
Query: 282 LEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKA 341
L++ +ED+G Y C+A N G + A P W K Q+ + +C+
Sbjct: 297 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQV 356
Query: 342 SGKPNPWYTWLKNG---ERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYAN 398
G+P P TW NG E L +++ +I+ G LI++ + SD+ V QC A N++ ++ AN
Sbjct: 357 QGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLAN 416
Query: 399 AELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISW--KRGTETLRQSKRI 456
A + V+ + + VQ G + CK P ++ W + GT T+ Q +R
Sbjct: 417 AYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT-TVLQDERF 474
Query: 457 FLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGES 516
F +G+L I ++ +D G Y C+A N +L VK+ T IT P G
Sbjct: 475 FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSR 534
Query: 517 IVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYL 576
+ CQ S DPS++ W GD DL++ + ++ E G L+I ++ G Y
Sbjct: 535 VTFTCQASFDPSLQPSITW--RGDGRDLQE-LGDSDKYFIED-GRLVIHSLDYSDQGNYS 590
Query: 577 CTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTS---QLSWRAGPDNNSPIQIFTI 633
C T L+ + + A ++V G PGP + + D+ T ++SW D+N+PI+ + I
Sbjct: 591 CVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDI 650
Query: 634 --QTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSE 691
+ + W ++ VP +T + LSP+V Y FRV A N G GEPS SE
Sbjct: 651 EFEDKEMAPEKWYSLGKVP-----GNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSE 705
Query: 692 LLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKE 751
+ T + P PV++ G G + +VITW+ + N Y + +RP G+ +E
Sbjct: 706 TVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQE 765
Query: 752 KVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSL 811
++ V V N S P+E+KV N++G+G VTI YSGED PQ P +
Sbjct: 766 QI--VSDPFLVVSNTS--TFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGI 821
Query: 812 QSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGK------IRVSGNVTTKN 865
+ ++S + V W + + G + GY V YW + S+ + + V N T+
Sbjct: 822 EILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVI 881
Query: 866 ITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEH 925
++GL+ + Y V+A+N G+GP+S +T + P P A +N+ L L W+
Sbjct: 882 LSGLRPYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQ- 939
Query: 926 VKTMENESEVLGYKILY 942
+ + + GY + Y
Sbjct: 940 -PPLSHNGVLTGYVLSY 955
Score = 82.4 bits (202), Expect = 2e-15
Identities = 141/684 (20%), Positives = 265/684 (38%), Gaps = 66/684 (9%)
Query: 335 LLWECKASGKPNPWYTWLKNGERLNPEERIQIENGTLIITMLNVS--DSGVYQCAAENKY 392
L+ EC A G P P WL+ + P +R+ +N + +L V D G Y+C AEN
Sbjct: 260 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 318
Query: 393 QIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRG---TET 449
+A + +AP + P + G + C+ P+ ++W+ E
Sbjct: 319 GSA-RHAYYVTVEAAPYWLHKP--QSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEE 375
Query: 450 LRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKE--RTVITVPPS 507
L + ++ + ++ G+L + N+ SD C A N+ G + V + ++T
Sbjct: 376 LAKDQK-YRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQ 434
Query: 508 KMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNI 567
G + L C+ P V W L+ ER + G L IR++
Sbjct: 435 TYMAVQGSTAYLLCKAFGAPVPSVQ--WLDEDGTTVLQD-----ERFFPYANGTLGIRDL 487
Query: 568 QLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSP 627
Q + +G+Y C +++ +A++ V+ + + I S++++ +
Sbjct: 488 QANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPR-STIEKKGSRVTFTCQASFDPS 546
Query: 628 IQIFTIQTRTPFSVGWQAVAT-VPEILNGKTY-----NATVVGLSPWVEYEFRVVAGNSI 681
+Q S+ W+ + E+ + Y + L + + VA +
Sbjct: 547 LQP---------SITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 597
Query: 682 GIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMF- 740
+ E ++ + VP + ++H ++S++ ++W P E N Y I F
Sbjct: 598 DVVESRAQLLVVGSPGPVPRLVLSDLHLL--TQSQVRVSWS--PAEDHNAPIEKYDIEFE 653
Query: 741 -RPVGSTTW-SKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVT-IVYS 797
+ + W S KV ++S + + P + +V N G G S V+ V +
Sbjct: 654 DKEMAPEKWYSLGKVPGNQTSTTL----KLSPYVHYTFRVTAINKYGPGEPSPVSETVVT 709
Query: 798 GEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRV 857
E P+ P + + M ++W + W + Y V + ++ +I
Sbjct: 710 PEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVS 769
Query: 858 SGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNV--TTKKSPPSQPPANIAWKLT 915
+ N + Y V+A N+ G GP P V + + + P + P L
Sbjct: 770 DPFLVVSNTSTFVP---YEIKVQAVNSQGKGPE-PQVTIGYSGEDYPQAIPELEGIEILN 825
Query: 916 NSKLCLNWEHVKTMENESEVLGYKILY----RQNRQSKTHI------LETNNTSAEL--L 963
+S + + W V + + + GY + Y Q + SK HI + N TS L L
Sbjct: 826 SSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGL 885
Query: 964 VPFEEDYLIEIRTVSDGGDGSSSE 987
P+ Y +E++ + G G +SE
Sbjct: 886 RPY-SSYHLEVQAFNGRGSGPASE 908
>gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 1257
Score = 379 bits (974), Expect = e-105
Identities = 281/977 (28%), Positives = 452/977 (46%), Gaps = 61/977 (6%)
Query: 1 MRLLWKLVILLPLI-----NSSAGDGLLSRPIFTQEPHD--VIFPLDLSKSEVILNCAAN 53
+R +W L++ P + G ++ P+ T++ V+FP D ++ L C A+
Sbjct: 5 LRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTD----DISLKCEAS 60
Query: 54 GYPSPHYRWKQNGTDI----DFTMSYHYRLDGGSLAI---NSPHTDQDIGMYQCLATNLL 106
G P +RW ++G + ++ + GS I NS + G+Y+C A+N L
Sbjct: 61 GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL 120
Query: 107 GTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYV 166
GT +S + +L + +T V V EG+ VVL C PPP L W N L++
Sbjct: 121 GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYW-MNSKILHI 179
Query: 167 QEDNRRFVSQETGNLYIAKVEPSDV-GNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEY 225
++D R + Q GNLY A V SD +Y C + +Q P L + M +
Sbjct: 180 KQDERVTMGQN-GNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDR 238
Query: 226 EPKIEVRFPET----IQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAI 281
+P++ FP + A + + LEC A G P P I W R G +V Y
Sbjct: 239 KPRL--LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKT 296
Query: 282 LEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKA 341
L++ +ED+G Y C+A N G + A P W K Q+ + +C+
Sbjct: 297 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQV 356
Query: 342 SGKPNPWYTWLKNG---ERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYAN 398
G+P P TW NG E L +++ +I+ G LI++ + SD+ V QC A N++ ++ AN
Sbjct: 357 QGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLAN 416
Query: 399 AELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISW--KRGTETLRQSKRI 456
A + V+ + + VQ G + CK P ++ W + GT T+ Q +R
Sbjct: 417 AYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT-TVLQDERF 474
Query: 457 FLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGES 516
F +G+L I ++ +D G Y C+A N +L VK+ T IT P G
Sbjct: 475 FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSR 534
Query: 517 IVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYL 576
+ CQ S DPS++ W GD DL++ + ++ E G L+I ++ G Y
Sbjct: 535 VTFTCQASFDPSLQPSITW--RGDGRDLQE-LGDSDKYFIED-GRLVIHSLDYSDQGNYS 590
Query: 577 CTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTS---QLSWRAGPDNNSPIQIFTI 633
C T L+ + + A ++V G PGP + + D+ T ++SW D+N+PI+ + I
Sbjct: 591 CVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDI 650
Query: 634 --QTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSE 691
+ + W ++ VP +T + LSP+V Y FRV A N G GEPS SE
Sbjct: 651 EFEDKEMAPEKWYSLGKVP-----GNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSE 705
Query: 692 LLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKE 751
+ T + P PV++ G G + +VITW+ + N Y + +RP G+ +E
Sbjct: 706 TVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQE 765
Query: 752 KVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSL 811
++ V V N S P+E+KV N++G+G VTI YSGED PQ P +
Sbjct: 766 QI--VSDPFLVVSNTS--TFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGI 821
Query: 812 QSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGK------IRVSGNVTTKN 865
+ ++S + V W + + G + GY V YW + S+ + + V N T+
Sbjct: 822 EILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVI 881
Query: 866 ITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEH 925
++GL+ + Y V+A+N G+GP+S +T + P P A +N+ L L W+
Sbjct: 882 LSGLRPYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQ- 939
Query: 926 VKTMENESEVLGYKILY 942
+ + + GY + Y
Sbjct: 940 -PPLSHNGVLTGYVLSY 955
Score = 82.4 bits (202), Expect = 2e-15
Identities = 141/684 (20%), Positives = 265/684 (38%), Gaps = 66/684 (9%)
Query: 335 LLWECKASGKPNPWYTWLKNGERLNPEERIQIENGTLIITMLNVS--DSGVYQCAAENKY 392
L+ EC A G P P WL+ + P +R+ +N + +L V D G Y+C AEN
Sbjct: 260 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 318
Query: 393 QIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRG---TET 449
+A + +AP + P + G + C+ P+ ++W+ E
Sbjct: 319 GSA-RHAYYVTVEAAPYWLHKP--QSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEE 375
Query: 450 LRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKE--RTVITVPPS 507
L + ++ + ++ G+L + N+ SD C A N+ G + V + ++T
Sbjct: 376 LAKDQK-YRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQ 434
Query: 508 KMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNI 567
G + L C+ P V W L+ ER + G L IR++
Sbjct: 435 TYMAVQGSTAYLLCKAFGAPVPSVQ--WLDEDGTTVLQD-----ERFFPYANGTLGIRDL 487
Query: 568 QLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSP 627
Q + +G+Y C +++ +A++ V+ + + I S++++ +
Sbjct: 488 QANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPR-STIEKKGSRVTFTCQASFDPS 546
Query: 628 IQIFTIQTRTPFSVGWQAVAT-VPEILNGKTY-----NATVVGLSPWVEYEFRVVAGNSI 681
+Q S+ W+ + E+ + Y + L + + VA +
Sbjct: 547 LQP---------SITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 597
Query: 682 GIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMF- 740
+ E ++ + VP + ++H ++S++ ++W P E N Y I F
Sbjct: 598 DVVESRAQLLVVGSPGPVPRLVLSDLHLL--TQSQVRVSWS--PAEDHNAPIEKYDIEFE 653
Query: 741 -RPVGSTTW-SKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVT-IVYS 797
+ + W S KV ++S + + P + +V N G G S V+ V +
Sbjct: 654 DKEMAPEKWYSLGKVPGNQTSTTL----KLSPYVHYTFRVTAINKYGPGEPSPVSETVVT 709
Query: 798 GEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRV 857
E P+ P + + M ++W + W + Y V + ++ +I
Sbjct: 710 PEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVS 769
Query: 858 SGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNV--TTKKSPPSQPPANIAWKLT 915
+ N + Y V+A N+ G GP P V + + + P + P L
Sbjct: 770 DPFLVVSNTSTFVP---YEIKVQAVNSQGKGPE-PQVTIGYSGEDYPQAIPELEGIEILN 825
Query: 916 NSKLCLNWEHVKTMENESEVLGYKILY----RQNRQSKTHI------LETNNTSAEL--L 963
+S + + W V + + + GY + Y Q + SK HI + N TS L L
Sbjct: 826 SSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGL 885
Query: 964 VPFEEDYLIEIRTVSDGGDGSSSE 987
P+ Y +E++ + G G +SE
Sbjct: 886 RPY-SSYHLEVQAFNGRGSGPASE 908
>gi|27894376 cell adhesion molecule with homology to L1CAM precursor
[Homo sapiens]
Length = 1224
Score = 355 bits (911), Expect = 1e-97
Identities = 264/957 (27%), Positives = 425/957 (44%), Gaps = 63/957 (6%)
Query: 27 IFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRL----DGG 82
I Q V FP D + C A G P P + W ++G FT +R+ + G
Sbjct: 37 IIKQSKVQVAFPFD---EYFQIECEAKGNPEPTFSWTKDGNPFYFT---DHRIIPSNNSG 90
Query: 83 SLAI-NSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVV 141
+ I N H G Y+C A+N LG +S + + + F + + V EG +V
Sbjct: 91 TFRIPNEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIV 150
Query: 142 LLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGN-YTCFITN 200
L C PP L W N ++++D R ++SQ+ G+LY A VE D N Y CF
Sbjct: 151 LPCNPPKGLPPLHIYW-MNIELEHIEQDERVYMSQK-GDLYFANVEEKDSRNDYCCFAAF 208
Query: 201 KEAQRSVQGPPTPLV---------QRTDGVMGEYEPKIEVRFPETI----QAAKDSSVK- 246
+ VQ P L + +G I+ R P+ + ++ +SS+
Sbjct: 209 PRLRTIVQKMPMKLTVNSLKHANDSSSSTEIGSKANSIKQRKPKLLLPPTESGSESSITI 268
Query: 247 -------LECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIA 299
LECFA G P P + W ++ G G+ L+I N +D+G Y C A
Sbjct: 269 LKGEILLLECFAEGLPTPQVDWNKIGGDLPKGRETKENYGKTLKIENVSYQDKGNYRCTA 328
Query: 300 SNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERL- 358
SN G +I PP W +K Q+ S N + C+A G+P P W NG +
Sbjct: 329 SNFLGTATHDFHVIVEEPPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPVD 388
Query: 359 -NPEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKK 417
+P + + T L + + VYQC A N + I ANA + V+ P +
Sbjct: 389 NHPFAGDVVFPREISFTNLQPNHTAVYQCEASNVHGTILANANIDVVDVRPLIQTKDGEN 448
Query: 418 KSFVQVGGDIVIGCKPNAFPRAAISWKRGTETL-RQSKRIFLLEDGSLKIYNITRSDAGS 476
+ V VG + C+ A P A +SW++ E + +R + E+G+L+I T DAGS
Sbjct: 449 YATV-VGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENGTLQINRTTEEDAGS 507
Query: 477 YTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIE--VVFV 534
Y+C N G T +L ++ T + V P + + L C+ D ++ +
Sbjct: 508 YSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHCESKCDSHLKHSLKLS 567
Query: 535 WFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIV 594
W +G+ ++ I G +L I N+ L G Y C+ T L+S + + + V
Sbjct: 568 WSKDGEAFEINGTEDGRIIIDG---ANLTISNVTLEDQGIYCCSAHTALDSAADITQVTV 624
Query: 595 RGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILN 654
P PPE++ + + + + +L+W AG D+NS I + ++ F + E+
Sbjct: 625 LDVPDPPENLHLSERQNRSVRLTWEAGADHNSNISEYIVE----FEGNKEEPGRWEELTR 680
Query: 655 GKTYNATVV-GLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGS 713
+ TV+ L+P+V Y+FRV+A N +G +PS+PS+ T + P P NI
Sbjct: 681 VQGKKTTVILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQ 740
Query: 714 RSELVITWESIPEELQNGEGFGYIIMFRPVGS-TTWSKEKVSSVESSRFVYRNESIIPLS 772
E++I WE + QNG G Y + ++P G+ W +E V++ R + +
Sbjct: 741 PKEMIIKWEPLKSMEQNGPGLEYRVTWKPQGAPVEWEEETVTN-----HTLRVMTPAVYA 795
Query: 773 PFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNT 832
P++VKV N G G +YSGED P AP + +++ ++V+W+ + +R
Sbjct: 796 PYDVKVQAINQLGSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTVPKDRVH 855
Query: 833 GRVLGYEVLYWTDDS------KESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAG 886
GR+ GY++ +W S + +R SG + + L A + + +V AYN+ G
Sbjct: 856 GRLKGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDAFSEFHLTVLAYNSKG 915
Query: 887 TGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILYR 943
GP S P T + P QP K+ L+W K + + GY + Y+
Sbjct: 916 AGPESEPYIFQTPEGVPEQPTFLKVIKVDKDTATLSWGLPKKL--NGNLTGYLLQYQ 970
>gi|81158224 neuronal cell adhesion molecule isoform B precursor
[Homo sapiens]
Length = 1183
Score = 337 bits (865), Expect = 3e-92
Identities = 270/944 (28%), Positives = 402/944 (42%), Gaps = 63/944 (6%)
Query: 22 LLSRPIFTQE-PHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGT--DIDFTMSYHYR 78
L+ P TQ+ P D I + +++ C A G P P + W +NGT DID +
Sbjct: 36 LVQPPTITQQSPKDYIID---PRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMK 92
Query: 79 LDGGSLAIN---SPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVR 135
G+L IN + G+YQC A N G +S ++ + + + ++++
Sbjct: 93 PGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQ 152
Query: 136 EGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVG-NY 194
GQ +VL C PP W DN + R G+LY + V P D +Y
Sbjct: 153 SGQSLVLPCRPPIGLPPPIIFWM--DNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDY 210
Query: 195 TCFITNKEAQRSVQGPPTPLV-----QRTDGVMGE------YEPKIEVRFPETI------ 237
C+ Q Q P + + D + Y K P T
Sbjct: 211 ICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGN 270
Query: 238 ----QAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEG 293
+ + + + LEC A G P P I W + DG + Y + L+I + + D G
Sbjct: 271 ASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSG 330
Query: 294 FYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLK 353
Y+CIA N G + A P W QN LS ++ C+A+G P P +WL
Sbjct: 331 NYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLT 390
Query: 354 NG---ERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDF 410
NG E + +I+ T+I + + S VYQC A N+Y + ANA + VLA P
Sbjct: 391 NGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI 450
Query: 411 SKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLL-EDGSLKIYNI 469
+P V ++ C P I W +G + + I++L E+G+L+I
Sbjct: 451 L-TPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVA 509
Query: 470 TRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSI 529
+ G+YTC+A N+ G AKN L +K+ T I P V G + C+V HD ++
Sbjct: 510 QKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTL 569
Query: 530 EVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAV 589
+ +W + + + ER + L++ ++ SG Y C TTL+S+SA
Sbjct: 570 SLTVLWLKDN------RELPSDERFTVDK-DHLVVADVSDDDSGTYTCVANTTLDSVSAS 622
Query: 590 ADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVG--WQAVA 647
A + V P PP D+++ D + QLSW G DNNSPI F I+ W
Sbjct: 623 AVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQT 682
Query: 648 TVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNI 707
V T + LSP+V Y FRV+A NSIG PSE SE TKAS P P +
Sbjct: 683 EV-----SGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAV 737
Query: 708 HGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPV-GSTTWSKEKVSSVESSRFVYRNE 766
G G LVITW+ + NG G Y + +R G W+ V++V Y
Sbjct: 738 EGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSK----YIVS 793
Query: 767 SIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAI 826
P+ +KV N+ G V + +SGED P +AP + +++ EV W+ +
Sbjct: 794 GTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPV 853
Query: 827 AWNRNTGRVLGYEVLYWTDDSKESMIGK------IRVSGNVTTKNITGLKANTIYFASVR 880
G + GY + YW S + + G+ T + GL+ + Y +VR
Sbjct: 854 PLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVR 913
Query: 881 AYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWE 924
N G GP+SP T + PS P + T L L W+
Sbjct: 914 VVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD 957
Score = 117 bits (294), Expect = 4e-26
Identities = 171/771 (22%), Positives = 301/771 (39%), Gaps = 63/771 (8%)
Query: 170 NRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKI 229
NR L I V +D GNY C N + T V + P
Sbjct: 308 NRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGA----------IHHTISVRVKAAP-Y 356
Query: 230 EVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPL---PGKVKYSKSQAILEIPN 286
+ P+ + + L C A GNP P ISW +G P+ P + N
Sbjct: 357 WITAPQNLVLSPGEDGTLICRANGNPKPRISWLT-NGVPIEIAPDDPSRKIDGDTIIFSN 415
Query: 287 FQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDN--LLWECKASGK 344
Q+ Y+C ASN G LA + A P NT + N L +C G
Sbjct: 416 VQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGS 475
Query: 345 PNPWYTWLKN--GERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELR 402
P P W K G L+ + + ENGTL I + +G Y C A NK + A E+
Sbjct: 476 PLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGM--AKNEVH 533
Query: 403 VLASAPDFS-KSPVKKKSFVQVGGDIVIGCKPNAFPRAAIS--WKRGTETLRQSKRIFLL 459
+ P + K P + + VQ G + CK +++ W + L +R F +
Sbjct: 534 LEIKDPTWIVKQP--EYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDER-FTV 590
Query: 460 EDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVL 519
+ L + +++ D+G+YTC+A + + L +V+ VP D+ + + +
Sbjct: 591 DKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVL-----SVVDVPNPPFDLELTDQLDK 645
Query: 520 PCQVSHDPSIE---VVFVWFFNGDVIDLKKGVAHFE-RIGGESVGDLMIRNIQLHHSGKY 575
Q+S P + + + + K G+ H + + G + + +++S +
Sbjct: 646 SVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRV 705
Query: 576 LCTVQTTLESLSAVAD--IIVRGPPGPPEDVQVEDISSTTSQL--SWRA--GPDNNSPIQ 629
+ V + +SL + A + + VE + S L +W+ G ++N P
Sbjct: 706 MA-VNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGL 764
Query: 630 IFTIQTRTPFSVG-WQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSE 688
+ + R W +V + N Y V G +V Y +V A N +G E
Sbjct: 765 QYKVSWRQKDGDDEWTSVV----VANVSKY--IVSGTPTFVPYLIKVQALNDMGFAP--E 816
Query: 689 PSELL-RTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTT 747
P+ ++ + +P+VAP N+ + + + W+ +P + G GY I + S++
Sbjct: 817 PAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSS 876
Query: 748 WS-----KEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEP 802
++K+ + + S+ + P S + + V V N +GEG S + + E P
Sbjct: 877 KRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVP 936
Query: 803 QLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESM--IGKIRVSGN 860
AP + + + + + W+ + G + Y + Y +S + + +++ N
Sbjct: 937 S-APSSLKIVNPTLDSLTLEWDPPS--HPNGILTEYTLKYQPINSTHELGPLVDLKIPAN 993
Query: 861 VTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIA 911
T + L +T Y A +AG+G VTT + +IA
Sbjct: 994 KTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMASRQVDIA 1044
Score = 83.6 bits (205), Expect = 9e-16
Identities = 103/437 (23%), Positives = 180/437 (41%), Gaps = 58/437 (13%)
Query: 213 PLVQRTDGVMGEYEPKIEVRFPETI--QAAKD------SSVKLECFALGNPVPDISWRR- 263
PL+ ++ E +++ P TI Q+ KD ++ ++C A G P P SW R
Sbjct: 18 PLILFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRN 77
Query: 264 -----LDGSPLPGKVKYSKSQAILEIPNFQQED--EGFYECIASNLRGRNLAKGQLIFYA 316
+D PL +K I+ I + + + EG Y+C A N RG ++ ++ +
Sbjct: 78 GTHFDIDKDPLV-TMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPS 136
Query: 317 -PPEW-EQKIQNTHLSIYDNLLWECKAS-GKPNPWYTWLKNG-ERLNPEERI-QIENGTL 371
P W ++K++ L +L+ C+ G P P W+ N +RL ER+ Q NG L
Sbjct: 137 RSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDL 196
Query: 372 IITMLNVSDSGV-YQCAAE-NKYQIIYANAELRVLASAPD-----------------FSK 412
+ + D+ Y C A N Q I + V + D
Sbjct: 197 YFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKS 256
Query: 413 SPVKKKSFVQVGGD-----------IVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLED 461
S + +F+ G+ + + C P I W + L +++ ++ +
Sbjct: 257 SRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFE 316
Query: 462 GSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPC 521
+L+I +++ +D+G+Y CIA N G +T S+ VK P + ++ GE L C
Sbjct: 317 KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLIC 376
Query: 522 QVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQT 581
+ + +P + W NG I++ +I G+++ + N+Q S Y C
Sbjct: 377 RANGNPKPRI--SWLTNGVPIEIAPDDPS-RKIDGDTI---IFSNVQERSSAVYQCNASN 430
Query: 582 TLESLSAVADIIVRGPP 598
L A A + V P
Sbjct: 431 EYGYLLANAFVNVLAEP 447
Score = 35.4 bits (80), Expect = 0.28
Identities = 53/242 (21%), Positives = 91/242 (37%), Gaps = 12/242 (4%)
Query: 748 WSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTI--VYSGEDEPQLA 805
W K+ RF + ++ + G Y +L +V+ V S D P
Sbjct: 575 WLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPN-P 633
Query: 806 PRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIG-KIRVSGNVTTK 864
P L +++SW + N + + + Y K + + VSG TT
Sbjct: 634 PFDLELTDQLDKSVQLSWTP--GDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTA 691
Query: 865 NITGLKANTIYFASVRAYNTAGTG-PSSPPVNVTTKKSPPSQPPANIAWKLTN-SKLCLN 922
+ L Y V A N+ G PS TK S P + P + + L +
Sbjct: 692 QLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVIT 750
Query: 923 WEHVKTMENESEVLGYKILYRQ-NRQSKTHILETNNTSAELL--VPFEEDYLIEIRTVSD 979
W+ + E+ L YK+ +RQ + + + N S ++ P YLI+++ ++D
Sbjct: 751 WKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALND 810
Query: 980 GG 981
G
Sbjct: 811 MG 812
>gi|81158226 neuronal cell adhesion molecule isoform A precursor
[Homo sapiens]
Length = 1304
Score = 333 bits (855), Expect = 4e-91
Identities = 271/956 (28%), Positives = 404/956 (42%), Gaps = 73/956 (7%)
Query: 20 DGLLSRPIFTQE-PHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGT--DIDFTMSYH 76
+ L+ P TQ+ P D I + +++ C A G P P + W +NGT DID
Sbjct: 40 EDLVQPPTITQQSPKDYIID---PRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVT 96
Query: 77 YRLDGGSLAIN---SPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVS 133
+ G+L IN + G+YQC A N G +S ++ + + + ++
Sbjct: 97 MKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPIT 156
Query: 134 VREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVG- 192
++ GQ +VL C PP W DN + R G+LY + V P D
Sbjct: 157 LQSGQSLVLPCRPPIGLPPPIIFWM--DNSFQRLPQSERVSQGLNGDLYFSNVLPEDTRE 214
Query: 193 NYTCFITNKEAQRSVQGPPTPLV-----QRTDGVMGE------YEPKIEVRFPETI---- 237
+Y C+ Q Q P + + D + Y K P T
Sbjct: 215 DYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPE 274
Query: 238 ------QAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQED 291
+ + + + LEC A G P P I W + DG + Y + L+I + + D
Sbjct: 275 GNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEAD 334
Query: 292 EGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTW 351
G Y+CIA N G + A P W QN LS ++ C+A+G P P +W
Sbjct: 335 SGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISW 394
Query: 352 LKNG---ERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAP 408
L NG E + +I+ T+I + + S VYQC A N+Y + ANA + VLA P
Sbjct: 395 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 454
Query: 409 DFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLL-EDGSLKIY 467
+P V ++ C P I W +G + + I++L E+G+L+I
Sbjct: 455 RIL-TPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIP 513
Query: 468 NITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDP 527
+ G+YTC+A N+ G AKN L +K+ T I P V G + C+V HD
Sbjct: 514 VAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDH 573
Query: 528 SIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLS 587
++ + +W + + + ER + L++ ++ SG Y C TTL+S+S
Sbjct: 574 TLSLTVLWLKDN------RELPSDERFTVDK-DHLVVADVSDDDSGTYTCVANTTLDSVS 626
Query: 588 AVADIIVRGP----------PGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRT 637
A A + V P P PP D+++ D + QLSW G DNNSPI F I+
Sbjct: 627 ASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYED 686
Query: 638 PFSVG--WQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRT 695
W V T + LSP+V Y FRV+A NSIG PSE SE T
Sbjct: 687 AMHKPGLWHHQTEV-----SGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLT 741
Query: 696 KASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPV-GSTTWSKEKVS 754
KAS P P + G G LVITW+ + NG G Y + +R G W+ V+
Sbjct: 742 KASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVA 801
Query: 755 SVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSF 814
+V Y P+ +KV N+ G V + +SGED P +AP +
Sbjct: 802 NVSK----YIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVV 857
Query: 815 SASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGK------IRVSGNVTTKNITG 868
+++ EV W+ + G + GY + YW S + + G+ T + G
Sbjct: 858 NSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPG 917
Query: 869 LKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWE 924
L+ + Y +VR N G GP+SP T + PS P + T L L W+
Sbjct: 918 LEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD 973
Score = 117 bits (294), Expect = 4e-26
Identities = 173/772 (22%), Positives = 299/772 (38%), Gaps = 63/772 (8%)
Query: 170 NRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKI 229
NR L I V +D GNY C N + T V + P
Sbjct: 314 NRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGA----------IHHTISVRVKAAP-Y 362
Query: 230 EVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPL---PGKVKYSKSQAILEIPN 286
+ P+ + + L C A GNP P ISW +G P+ P + N
Sbjct: 363 WITAPQNLVLSPGEDGTLICRANGNPKPRISWLT-NGVPIEIAPDDPSRKIDGDTIIFSN 421
Query: 287 FQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDN--LLWECKASGK 344
Q+ Y+C ASN G LA + A P NT + N L +C G
Sbjct: 422 VQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGS 481
Query: 345 PNPWYTWLKN--GERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELR 402
P P W K G L+ + + ENGTL I + +G Y C A NK + A E+
Sbjct: 482 PLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGM--AKNEVH 539
Query: 403 VLASAPDFS-KSPVKKKSFVQVGGDIVIGCKPNAFPRAAIS--WKRGTETLRQSKRIFLL 459
+ P + K P + + VQ G + CK +++ W + L +R F +
Sbjct: 540 LEIKDPTWIVKQP--EYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDER-FTV 596
Query: 460 EDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERT-----VITVPPSKMDVTVG 514
+ L + +++ D+G+YTC+A + + L V T V VP D+ +
Sbjct: 597 DKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELT 656
Query: 515 ESIVLPCQVSHDPSIE---VVFVWFFNGDVIDLKKGVAHFE-RIGGESVGDLMIRNIQLH 570
+ + Q+S P + + + + K G+ H + + G + + ++
Sbjct: 657 DQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVN 716
Query: 571 HSGKYLCTVQTTLESLSAVAD--IIVRGPPGPPEDVQVEDISSTTSQL--SWRA--GPDN 624
+S + + V + +SL + A + + VE + S L +W+ G ++
Sbjct: 717 YSFRVMA-VNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFES 775
Query: 625 NSPIQIFTIQTRTPFSVG-WQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGI 683
N P + + R W +V + N Y V G +V Y +V A N +G
Sbjct: 776 NGPGLQYKVSWRQKDGDDEWTSVV----VANVSKY--IVSGTPTFVPYLIKVQALNDMGF 829
Query: 684 GEPSEPSELL-RTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRP 742
EP+ ++ + +P+VAP N+ + + + W+ +P + G GY I +
Sbjct: 830 AP--EPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWK 887
Query: 743 VGSTTWS-----KEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYS 797
S++ ++K+ + + S+ + P S + + V V N +GEG S + +
Sbjct: 888 TQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNT 947
Query: 798 GEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESM--IGKI 855
E P AP + + + + + W+ + G + Y + Y +S + + +
Sbjct: 948 PEGVPS-APSSLKIVNPTLDSLTLEWDPPS--HPNGILTEYTLKYQPINSTHELGPLVDL 1004
Query: 856 RVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPP 907
++ N T + L +T Y A +AG+G VTT PP
Sbjct: 1005 KIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPP 1056
Score = 33.5 bits (75), Expect = 1.1
Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 6/130 (4%)
Query: 857 VSGNVTTKNITGLKANTIYFASVRAYNTAGTG-PSSPPVNVTTKKSPPSQPPANIAWKLT 915
VSG TT + L Y V A N+ G PS TK S P + P + +
Sbjct: 700 VSGTQTTAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGS 758
Query: 916 N-SKLCLNWEHVKTMENESEVLGYKILYRQ-NRQSKTHILETNNTSAELL--VPFEEDYL 971
L + W+ + E+ L YK+ +RQ + + + N S ++ P YL
Sbjct: 759 EPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYL 818
Query: 972 IEIRTVSDGG 981
I+++ ++D G
Sbjct: 819 IKVQALNDMG 828
>gi|237858679 neurofascin isoform 3 precursor [Homo sapiens]
Length = 1174
Score = 319 bits (818), Expect = 7e-87
Identities = 249/938 (26%), Positives = 400/938 (42%), Gaps = 60/938 (6%)
Query: 43 KSEVILNCAANGYPSPHYRWKQNGTDIDFTMS--YHYRLDGGSLAIN---SPHTDQDIGM 97
+ +++ C A G P+P + W +N + R G+L I+ ++ G
Sbjct: 50 RDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 109
Query: 98 YQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAW 157
YQC A N GT LS + +LQ + + + V V+EG + L C PPP W
Sbjct: 110 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 169
Query: 158 TFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVG-NYTCFITNKEAQRSVQGPPTPLVQ 216
+ Q+ +R G+LY + V D+ +Y+C Q P L
Sbjct: 170 MSSSMEPITQD--KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKV 227
Query: 217 RTD---------------GVMGEYEPKIEVRFPETIQAA----KDSSVKLECFALGNPVP 257
T+ G E +P+ ++ + + LEC A G P P
Sbjct: 228 LTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTP 287
Query: 258 DISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAP 317
DI+W + G K K+ L I N +ED G Y C+ASN G + A
Sbjct: 288 DIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAA 347
Query: 318 PEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLN---PEERIQIENGTLIIT 374
P W + +N L+ ++ C+A+G P P W+ NGE L P ++ T+I
Sbjct: 348 PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFR 407
Query: 375 MLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPN 434
+S VYQC N++ + ANA + VL P SP + V + + C
Sbjct: 408 DTQISSRAVYQCNTSNEHGYLLANAFVSVL-DVPPRMLSPRNQLIRVILYNRTRLDCPFF 466
Query: 435 AFPRAAISW-KRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGS 493
P + W K G + + E+GSL+I I + D G YTC+ATN G A+N
Sbjct: 467 GSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR 526
Query: 494 LIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFER 553
L VK+ T I P G ++ L C+V HDPS+++ W + + + + +
Sbjct: 527 LEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK---- 582
Query: 554 IGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTT 613
+ L I + G Y C T L+ A A + V G P P D+++ D++ +
Sbjct: 583 ---KEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRDLELTDLAERS 639
Query: 614 SQLSWRAGPDNNSPIQIFTIQ-TRTPFSVG-WQAVATVPEILNGKTYNATVVGLSPWVEY 671
+L+W G NNSPI + +Q F G W + P + N+ V+ LSP+V Y
Sbjct: 640 VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP-----GSVNSAVLRLSPYVNY 694
Query: 672 EFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNG 731
+FRV+A N +G PS PSE RT + P P ++ G G ++ + ITW + G
Sbjct: 695 QFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFG 754
Query: 732 EGFGYIIMFRPVGS-TTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLS 790
YI+ +R + W+ +V SR+V + P+E++V N+ G+G
Sbjct: 755 PNLRYIVKWRRRETREAWNN---VTVWGSRYVVGQTPV--YVPYEIRVQAENDFGKGPEP 809
Query: 791 TVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDS--K 848
I YSGED P+ AP ++ +++ + + WN + + G++ Y YW + S K
Sbjct: 810 ESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLK 869
Query: 849 ESMIGKIRVSGNVTTKNITGLKANTIYFASVR----AYNTAGTGPSSPPVNVTTKKSPPS 904
+ + R + + G+ + +++ + N G GP S TT + PS
Sbjct: 870 NLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPS 929
Query: 905 QPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILY 942
P + + L W+H + ++GY + Y
Sbjct: 930 APRRFRVRQPNLETINLEWDHPE--HPNGIMIGYTLKY 965
Score = 78.6 bits (192), Expect = 3e-14
Identities = 101/424 (23%), Positives = 171/424 (40%), Gaps = 54/424 (12%)
Query: 223 GEYEPKIEVRFPETI--QAAKD------SSVKLECFALGNPVPDISWRR------LDGSP 268
G E +++ P TI Q+AKD ++ +EC A GNP P W R + P
Sbjct: 23 GAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDP 82
Query: 269 LPGKVKYSKSQAI-LEIPNFQQEDEGFYECIASNLRGRNLA-KGQLIFYAPPEW-EQKIQ 325
+ S + I +E EG Y+C A N G L+ + +L P W ++ +
Sbjct: 83 RVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLD 142
Query: 326 NTHLSIYDNLLWECK-ASGKPNPWYTWLKNG-ERLNPEERI-QIENGTLIITMLNVSDSG 382
+ L +C G P+P W+ + E + ++R+ Q NG L + + + D
Sbjct: 143 PVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQ 202
Query: 383 V-YQCAA----------ENKYQI------IYANAELR----------VLASAPDFS-KSP 414
Y C A +N + + Y ++ LR V P F
Sbjct: 203 TDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQG 262
Query: 415 VKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDA 474
V G D+++ C + P I+W + L K F + +L+I N++ D+
Sbjct: 263 TASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDS 322
Query: 475 GSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFV 534
G Y C+A+N+ G+ ++T S+ VK P + + GE L C+ + +P V
Sbjct: 323 GEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTV--Q 380
Query: 535 WFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIV 594
W NG+ + + E + G+++ + R+ Q+ Y C L A A + V
Sbjct: 381 WMVNGEPLQSAPPNPNRE-VAGDTI---IFRDTQISSRAVYQCNTSNEHGYLLANAFVSV 436
Query: 595 RGPP 598
P
Sbjct: 437 LDVP 440
Score = 33.9 bits (76), Expect = 0.81
Identities = 44/231 (19%), Positives = 81/231 (35%), Gaps = 16/231 (6%)
Query: 597 PPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQI-----FTIQTRTPFSVGWQAVATVPE 651
P P +V+V ++ST L W + Q+ + + + W +
Sbjct: 821 PRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQA 880
Query: 652 ILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGG 711
G V L P+ Y+ +V N G G SE E T VP AP
Sbjct: 881 SFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFT-TPEGVPS-APRRFRVRQ 938
Query: 712 GSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPL 771
+ + + W+ E NG GY + + T K+ V + ++ + + P+
Sbjct: 939 PNLETINLEWDH--PEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPV 996
Query: 772 SPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVS 822
S + + G G T E+ P T +++ ++ +++
Sbjct: 997 SRYRFTLSARTQVGSGEAVT-------EESPAPPNEATPTAAYTNNQADIA 1040
>gi|89903008 neurofascin isoform 4 precursor [Homo sapiens]
Length = 1169
Score = 319 bits (818), Expect = 7e-87
Identities = 249/938 (26%), Positives = 400/938 (42%), Gaps = 60/938 (6%)
Query: 43 KSEVILNCAANGYPSPHYRWKQNGTDIDFTMS--YHYRLDGGSLAIN---SPHTDQDIGM 97
+ +++ C A G P+P + W +N + R G+L I+ ++ G
Sbjct: 50 RDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 109
Query: 98 YQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAW 157
YQC A N GT LS + +LQ + + + V V+EG + L C PPP W
Sbjct: 110 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 169
Query: 158 TFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVG-NYTCFITNKEAQRSVQGPPTPLVQ 216
+ Q+ +R G+LY + V D+ +Y+C Q P L
Sbjct: 170 MSSSMEPITQD--KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKV 227
Query: 217 RTD---------------GVMGEYEPKIEVRFPETIQAA----KDSSVKLECFALGNPVP 257
T+ G E +P+ ++ + + LEC A G P P
Sbjct: 228 LTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTP 287
Query: 258 DISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAP 317
DI+W + G K K+ L I N +ED G Y C+ASN G + A
Sbjct: 288 DIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAA 347
Query: 318 PEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLN---PEERIQIENGTLIIT 374
P W + +N L+ ++ C+A+G P P W+ NGE L P ++ T+I
Sbjct: 348 PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFR 407
Query: 375 MLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPN 434
+S VYQC N++ + ANA + VL P SP + V + + C
Sbjct: 408 DTQISSRAVYQCNTSNEHGYLLANAFVSVL-DVPPRMLSPRNQLIRVILYNRTRLDCPFF 466
Query: 435 AFPRAAISW-KRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGS 493
P + W K G + + E+GSL+I I + D G YTC+ATN G A+N
Sbjct: 467 GSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR 526
Query: 494 LIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFER 553
L VK+ T I P G ++ L C+V HDPS+++ W + + + + +
Sbjct: 527 LEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK---- 582
Query: 554 IGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTT 613
+ L I + G Y C T L+ A A + V G P P D+++ D++ +
Sbjct: 583 ---KEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRDLELTDLAERS 639
Query: 614 SQLSWRAGPDNNSPIQIFTIQ-TRTPFSVG-WQAVATVPEILNGKTYNATVVGLSPWVEY 671
+L+W G NNSPI + +Q F G W + P + N+ V+ LSP+V Y
Sbjct: 640 VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP-----GSVNSAVLRLSPYVNY 694
Query: 672 EFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNG 731
+FRV+A N +G PS PSE RT + P P ++ G G ++ + ITW + G
Sbjct: 695 QFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFG 754
Query: 732 EGFGYIIMFRPVGS-TTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLS 790
YI+ +R + W+ +V SR+V + P+E++V N+ G+G
Sbjct: 755 PNLRYIVKWRRRETREAWNN---VTVWGSRYVVGQTPV--YVPYEIRVQAENDFGKGPEP 809
Query: 791 TVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDS--K 848
I YSGED P+ AP ++ +++ + + WN + + G++ Y YW + S K
Sbjct: 810 ESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLK 869
Query: 849 ESMIGKIRVSGNVTTKNITGLKANTIYFASVR----AYNTAGTGPSSPPVNVTTKKSPPS 904
+ + R + + G+ + +++ + N G GP S TT + PS
Sbjct: 870 NLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPS 929
Query: 905 QPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILY 942
P + + L W+H + ++GY + Y
Sbjct: 930 APRRFRVRQPNLETINLEWDHPE--HPNGIMIGYTLKY 965
Score = 78.6 bits (192), Expect = 3e-14
Identities = 101/424 (23%), Positives = 171/424 (40%), Gaps = 54/424 (12%)
Query: 223 GEYEPKIEVRFPETI--QAAKD------SSVKLECFALGNPVPDISWRR------LDGSP 268
G E +++ P TI Q+AKD ++ +EC A GNP P W R + P
Sbjct: 23 GAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDP 82
Query: 269 LPGKVKYSKSQAI-LEIPNFQQEDEGFYECIASNLRGRNLA-KGQLIFYAPPEW-EQKIQ 325
+ S + I +E EG Y+C A N G L+ + +L P W ++ +
Sbjct: 83 RVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLD 142
Query: 326 NTHLSIYDNLLWECK-ASGKPNPWYTWLKNG-ERLNPEERI-QIENGTLIITMLNVSDSG 382
+ L +C G P+P W+ + E + ++R+ Q NG L + + + D
Sbjct: 143 PVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQ 202
Query: 383 V-YQCAA----------ENKYQI------IYANAELR----------VLASAPDFS-KSP 414
Y C A +N + + Y ++ LR V P F
Sbjct: 203 TDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQG 262
Query: 415 VKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDA 474
V G D+++ C + P I+W + L K F + +L+I N++ D+
Sbjct: 263 TASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDS 322
Query: 475 GSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFV 534
G Y C+A+N+ G+ ++T S+ VK P + + GE L C+ + +P V
Sbjct: 323 GEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTV--Q 380
Query: 535 WFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIV 594
W NG+ + + E + G+++ + R+ Q+ Y C L A A + V
Sbjct: 381 WMVNGEPLQSAPPNPNRE-VAGDTI---IFRDTQISSRAVYQCNTSNEHGYLLANAFVSV 436
Query: 595 RGPP 598
P
Sbjct: 437 LDVP 440
Score = 33.1 bits (74), Expect = 1.4
Identities = 41/200 (20%), Positives = 69/200 (34%), Gaps = 9/200 (4%)
Query: 597 PPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQI-----FTIQTRTPFSVGWQAVATVPE 651
P P +V+V ++ST L W + Q+ + + + W +
Sbjct: 821 PRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQA 880
Query: 652 ILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGG 711
G V L P+ Y+ +V N G G SE E T VP AP
Sbjct: 881 SFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFT-TPEGVPS-APRRFRVRQ 938
Query: 712 GSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPL 771
+ + + W+ E NG GY + + T K+ V + ++ + + P+
Sbjct: 939 PNLETINLEWDH--PEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPV 996
Query: 772 SPFEVKVGVYNNEGEGSLST 791
S + + G G T
Sbjct: 997 SRYRFTLSARTQVGSGEAVT 1016
>gi|237858677 neurofascin isoform 2 precursor [Homo sapiens]
Length = 1189
Score = 311 bits (798), Expect = 2e-84
Identities = 249/953 (26%), Positives = 403/953 (42%), Gaps = 75/953 (7%)
Query: 43 KSEVILNCAANGYPSPHYRWKQNGTDIDFTMS--YHYRLDGGSLAIN---SPHTDQDIGM 97
+ +++ C A G P+P + W +N + R G+L I+ ++ G
Sbjct: 50 RDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 109
Query: 98 YQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAW 157
YQC A N GT LS + +LQ + + + V V+EG + L C PPP W
Sbjct: 110 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 169
Query: 158 TFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVG-NYTCFITNKEAQRSVQGPPTPLVQ 216
+ Q+ +R G+LY + V D+ +Y+C Q P L
Sbjct: 170 MSSSMEPITQD--KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKV 227
Query: 217 RTD---------------GVMGEYEPKIEVRFPETIQAA----KDSSVKLECFALGNPVP 257
T+ G E +P+ ++ + + LEC A G P P
Sbjct: 228 LTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTP 287
Query: 258 DISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAP 317
DI+W + G K K+ L I N +ED G Y C+ASN G + A
Sbjct: 288 DIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAA 347
Query: 318 PEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLN---PEERIQIENGTLIIT 374
P W + +N L+ ++ C+A+G P P W+ NGE L P ++ T+I
Sbjct: 348 PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFR 407
Query: 375 MLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPN 434
+S VYQC N++ + ANA + VL P SP + V + + C
Sbjct: 408 DTQISSRAVYQCNTSNEHGYLLANAFVSVL-DVPPRMLSPRNQLIRVILYNRTRLDCPFF 466
Query: 435 AFPRAAISW-KRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGS 493
P + W K G + + E+GSL+I I + D G YTC+ATN G A+N
Sbjct: 467 GSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR 526
Query: 494 LIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFER 553
L VK+ T I P G ++ L C+V HDPS+++ W + + + + +
Sbjct: 527 LEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK---- 582
Query: 554 IGGESVGDLMIRNIQLHHSGKYLCTVQTTLES------LSAVAD---------IIVRGPP 598
+ L I + G Y C T L+ L+ +AD + +G P
Sbjct: 583 ---KEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRP 639
Query: 599 GPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQ-TRTPFSVG-WQAVATVPEILNGK 656
P D+++ D++ + +L+W G NNSPI + +Q F G W + P
Sbjct: 640 DRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP-----G 694
Query: 657 TYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSE 716
+ N+ V+ LSP+V Y+FRV+A N +G PS PSE RT + P P ++ G G ++
Sbjct: 695 SVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNN 754
Query: 717 LVITWESIPEELQNGEGFGYIIMFRPVGS-TTWSKEKVSSVESSRFVYRNESIIPLSPFE 775
+ ITW + G YI+ +R + W+ +V SR+V + P+E
Sbjct: 755 MEITWTPMNATSAFGPNLRYIVKWRRRETREAWNN---VTVWGSRYVVGQTPV--YVPYE 809
Query: 776 VKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRV 835
++V N+ G+G I YSGED P+ AP ++ +++ + + WN + + G++
Sbjct: 810 IRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQL 869
Query: 836 LGYEVLYWTDDS--KESMIGKIRVSGNVTTKNITGLKANTIYFASVR----AYNTAGTGP 889
Y YW + S K + + R + + G+ + +++ + N G GP
Sbjct: 870 REYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGP 929
Query: 890 SSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILY 942
S TT + PS P + + L W+H + ++GY + Y
Sbjct: 930 RSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPE--HPNGIMIGYTLKY 980
Score = 78.6 bits (192), Expect = 3e-14
Identities = 101/424 (23%), Positives = 171/424 (40%), Gaps = 54/424 (12%)
Query: 223 GEYEPKIEVRFPETI--QAAKD------SSVKLECFALGNPVPDISWRR------LDGSP 268
G E +++ P TI Q+AKD ++ +EC A GNP P W R + P
Sbjct: 23 GAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDP 82
Query: 269 LPGKVKYSKSQAI-LEIPNFQQEDEGFYECIASNLRGRNLA-KGQLIFYAPPEW-EQKIQ 325
+ S + I +E EG Y+C A N G L+ + +L P W ++ +
Sbjct: 83 RVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLD 142
Query: 326 NTHLSIYDNLLWECK-ASGKPNPWYTWLKNG-ERLNPEERI-QIENGTLIITMLNVSDSG 382
+ L +C G P+P W+ + E + ++R+ Q NG L + + + D
Sbjct: 143 PVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQ 202
Query: 383 V-YQCAA----------ENKYQI------IYANAELR----------VLASAPDFS-KSP 414
Y C A +N + + Y ++ LR V P F
Sbjct: 203 TDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQG 262
Query: 415 VKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDA 474
V G D+++ C + P I+W + L K F + +L+I N++ D+
Sbjct: 263 TASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDS 322
Query: 475 GSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFV 534
G Y C+A+N+ G+ ++T S+ VK P + + GE L C+ + +P V
Sbjct: 323 GEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTV--Q 380
Query: 535 WFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIV 594
W NG+ + + E + G+++ + R+ Q+ Y C L A A + V
Sbjct: 381 WMVNGEPLQSAPPNPNRE-VAGDTI---IFRDTQISSRAVYQCNTSNEHGYLLANAFVSV 436
Query: 595 RGPP 598
P
Sbjct: 437 LDVP 440
Score = 33.9 bits (76), Expect = 0.81
Identities = 44/231 (19%), Positives = 81/231 (35%), Gaps = 16/231 (6%)
Query: 597 PPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQI-----FTIQTRTPFSVGWQAVATVPE 651
P P +V+V ++ST L W + Q+ + + + W +
Sbjct: 836 PRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQA 895
Query: 652 ILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGG 711
G V L P+ Y+ +V N G G SE E T VP AP
Sbjct: 896 SFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFT-TPEGVPS-APRRFRVRQ 953
Query: 712 GSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPL 771
+ + + W+ E NG GY + + T K+ V + ++ + + P+
Sbjct: 954 PNLETINLEWDH--PEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPV 1011
Query: 772 SPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVS 822
S + + G G T E+ P T +++ ++ +++
Sbjct: 1012 SRYRFTLSARTQVGSGEAVT-------EESPAPPNEATPTAAYTNNQADIA 1055
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 311 bits (796), Expect = 3e-84
Identities = 272/1020 (26%), Positives = 452/1020 (44%), Gaps = 80/1020 (7%)
Query: 3 LLWKLVILLPLINSSAGDGLLSRPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRW 62
L+W L+ L + + A D + P F EP V + L + ++L C A G ++W
Sbjct: 5 LIWTLLALHQIRAARAQDDV--SPYFKTEP--VRTQVHLEGNRLVLTCMAEGSWPLEFKW 60
Query: 63 KQNGTDID-FTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYI 121
N ++ F++ Y Y + +++ H G Y+C+ N +G +L R+ ++Q AY+
Sbjct: 61 LHNNRELTKFSLEYRYMIT----SLDRTHA----GFYRCIVRNRMGALLQRQTEVQVAYM 112
Query: 122 EDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNL 181
FE + SV G+ V+ F W F D + +R ++ E +
Sbjct: 113 GSFEEGEKHQ-SVSHGEAAVIRAPRIASFPQPQVTW-FRDGRK-IPPSSRIAITLENTLV 169
Query: 182 YIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAK 241
++ V P Y + +K P T V+ G P I + T A
Sbjct: 170 ILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAG 229
Query: 242 DSSVKLECFALGNPVPD--ISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIA 299
S V LEC A P+ I W++ DG L G + S L IPN D G+YEC A
Sbjct: 230 TSEVTLECVANARPLIKLHIIWKK-DGVLLSGGI--SDHNRRLTIPNPTGSDAGYYECEA 286
Query: 300 SNLRGRNL---AKGQLIFYAPPEWEQKIQNTHLSIYDNLLWE--CKASGKPNPWYTWLKN 354
LR ++ +G + P K H++ + + C+A G P P TW K+
Sbjct: 287 V-LRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKD 345
Query: 355 GERLNPEERI---QIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFS 411
+ E+ Q +G L I+ L D+G++QC A N + + L V + AP+ +
Sbjct: 346 AAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNIT 405
Query: 412 KSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLR----QSKRIFLLEDGSLKIY 467
+ P+ S V G +V+ C+ + PR AI+W++G L Q R LE GSL I
Sbjct: 406 RGPLD--STVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLIS 463
Query: 468 NITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDP 527
SDAG+YTC+ATN G + + L+V RT IT PP V G + C V+HDP
Sbjct: 464 PTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDP 523
Query: 528 SIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLS 587
+ + ++W +G + G RI + G L I G Y C V + + S
Sbjct: 524 RVTIRYIWEKDGATL----GTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDS 579
Query: 588 AVADIIVRGPPGPPED--VQVEDISSTTSQLSWRAGPDNNSPIQIFTI---QTRTPFSVG 642
A + VR P PE + + L+W D NSP+ + + + P++V
Sbjct: 580 RSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVL 639
Query: 643 WQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVV 702
+V + K + TV GL P Y+FR+ A N +G G+ S+ +E + P
Sbjct: 640 LASV-------DPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTA 692
Query: 703 APVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMF----RPVGSTTWSKEKVSSVES 758
P N+ G + ++I W+ PE QNG GYII + PVG + + ++ +
Sbjct: 693 PPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVG---YQFKNITDADV 749
Query: 759 SRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASE 818
+ + E +I + +E++V YN+ G G S+ ++ + P + P ++ +++
Sbjct: 750 NNLLL--EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTT 807
Query: 819 MEVSWNAIAWNRNTGRVLGYEVLYWTDDSKES---MIGKIRVSGNVTTKNITGLKANTIY 875
+ +WNA + G GY+++ W + +E + + ++ ++GLK T Y
Sbjct: 808 IRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEY 867
Query: 876 FASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAW-KLTNSKLCLNWEHVKTMENESE 934
F SV + T G GP S P V T + P P ++++ ++ ++ L ++W+ + E
Sbjct: 868 FTSVLCFTTPGDGPRSTPQLVRTHEDVPG-PVGHLSFSEILDTSLKVSWQ--EPGEKNGI 924
Query: 935 VLGYKILYRQNRQSKTHI--------LETNNTSAELLVPFEEDYLIEIRTVSDGGDGSSS 986
+ GY+I + + ++ T + LE T L Y IE+ ++ G G S
Sbjct: 925 LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALT----TYTIEVAAMTSKGQGQVS 980
Score = 146 bits (369), Expect = 9e-35
Identities = 110/376 (29%), Positives = 182/376 (48%), Gaps = 39/376 (10%)
Query: 595 RGPPGPPED--VQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEI 652
R P PP VQ ED+ + + LSW G D SP++ +TIQTR S W A+ +
Sbjct: 1397 RDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRW-ALHSASVS 1455
Query: 653 LNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGG 712
N ++ V L P+ Y+FRV A N IG E SE SE L T + P AP +
Sbjct: 1456 HNASSF--IVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPH 1513
Query: 713 SRSELVITWESIPEELQNGEGFGYIIMFRPV---------------GSTTWSKEKVSSVE 757
+ + ++I W+ E+ NG G+ I +R + TW++ ++S+
Sbjct: 1514 TTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAE--LTSMY 1571
Query: 758 SSRFV-------YRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTS 810
S R + Y +++ +E+++ VYN GEG S V+ GE P APR
Sbjct: 1572 SMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVV 1631
Query: 811 LQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIR----VSGNVTTKNI 866
+ +A++++V+W + G + GY++ +W + + ++ +++ +V KN+
Sbjct: 1632 VHGATATQLDVTWEPPPLDSQNGDIQGYKIYFW-EAQRGNLTERVKTLFLAENSVKLKNL 1690
Query: 867 TGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHV 926
TG T Y SV A+N AG GP S P T+++ PS P + +LT + + ++WE
Sbjct: 1691 TGY---TAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAP 1747
Query: 927 KTMENESEVLGYKILY 942
+ E GY+++Y
Sbjct: 1748 QFPNGILE--GYRLVY 1761
Score = 115 bits (287), Expect = 3e-25
Identities = 99/392 (25%), Positives = 165/392 (42%), Gaps = 17/392 (4%)
Query: 585 SLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQ 644
S S ++ + PGPP ++ + +I + L +R G D + I + ++ + +
Sbjct: 980 SASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGE 1039
Query: 645 AVATVPEILNGKTYNATVV-GLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVA 703
+ ++ N + V L+P+ Y FR+ N +G PS+PS ++T + P +A
Sbjct: 1040 EWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMA 1099
Query: 704 PVNIHGGGGSRSELVITWESIPEELQNG--EGFGYIIMF-RPVG-STTWSKEKVSSVESS 759
P N+ S + L + W +PE NG E GY I + R G T S VE
Sbjct: 1100 PANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERD 1159
Query: 760 RFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEM 819
Y E + + + V+V +N G G S + + E P P S + ++S M
Sbjct: 1160 ---YTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSM 1216
Query: 820 EVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYFASV 879
V W+ + G VLGY+V+Y DS + + + +TGL +Y V
Sbjct: 1217 LVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQV 1276
Query: 880 RAYNTAGTG-PSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGY 938
A+ G G PS PP+ T P P + ++ + + L W+ +L Y
Sbjct: 1277 LAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQ--PPAAPNGIILAY 1334
Query: 939 KILYRQNRQSKTHILETNNTSAELLVPFEEDY 970
+I +R N + N + E+L P Y
Sbjct: 1335 QITHRLNTTT------ANTATVEVLAPSARQY 1360
Score = 96.3 bits (238), Expect = 1e-19
Identities = 95/406 (23%), Positives = 172/406 (42%), Gaps = 25/406 (6%)
Query: 597 PPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGK 656
P P +V + S T+ L W P+ ++ + +S T+ ++ +
Sbjct: 1096 PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDR 1155
Query: 657 TY-NATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRS 715
+ T+ L W EY +V A N+IG G P + + RT+ SVP P N+ + S
Sbjct: 1156 VERDYTIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRTRESVPSSGPTNVSALATTSS 1214
Query: 716 ELVITWESIPEELQNGEGFGYIIMFRPVGSTT----WSKEKVSSVESSRFVYRNESIIPL 771
+++ W +PE +NG GY +M++ S T W E SS S++ + ++
Sbjct: 1215 SMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSS-RSAQLTGLGKYVL-- 1271
Query: 772 SPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRN 831
+EV+V + G+GS S I+ D+ P G + + + W A
Sbjct: 1272 --YEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPA--AP 1327
Query: 832 TGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSS 891
G +L Y++ + + + + ++ + TGLK ++Y + A G G ++
Sbjct: 1328 NGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAA 1387
Query: 892 PPVNVTTKKSPPSQPPANIAWKLTNSK---LCLNWEHVKTMENESEVLGYKILYRQNRQS 948
+ VTT+K QPP+ + + + + L+WE + S V Y I R+
Sbjct: 1388 EALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE--PGSDGLSPVRYYTIQTRELPSG 1445
Query: 949 K--THILETNNTSAELLV----PFEEDYLIEIRTVSDGGDGSSSEE 988
+ H ++ ++ +V PF Y ++ +D GD SEE
Sbjct: 1446 RWALHSASVSHNASSFIVDRLKPF-TSYKFRVKATNDIGDSEFSEE 1490
Score = 61.6 bits (148), Expect = 4e-09
Identities = 70/293 (23%), Positives = 123/293 (41%), Gaps = 16/293 (5%)
Query: 659 NATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELV 718
+A + GL +V YE +V+A IG G PS P L RT VP P+ I + +
Sbjct: 1260 SAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPG-PPMGILFPEVRTTSVR 1318
Query: 719 ITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKV 778
+ W+ P NG Y I R + +TT + V + S Y + P S + ++
Sbjct: 1319 LIWQ--PPAAPNGIILAYQITHR-LNTTTANTATVEVLAPSARQYTATGLKPESVYLFRI 1375
Query: 779 GVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGY 838
+G G + +V + + + P +Q V ++W + +
Sbjct: 1376 TAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSV---LLSWEPGSDGLS-- 1430
Query: 839 EVLYWTDDSKESMIGK-----IRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGP-SSP 892
V Y+T ++E G+ VS N ++ + LK T Y V+A N G S
Sbjct: 1431 PVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEE 1490
Query: 893 PVNVTTKKSPPSQPPANIA-WKLTNSKLCLNWEHVKTMENESEVLGYKILYRQ 944
++TT ++ P + P ++ T + + + W+ + +LG++I YR+
Sbjct: 1491 SESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRE 1543
Score = 53.9 bits (128), Expect = 8e-07
Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 7/106 (6%)
Query: 596 GPPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQA-VATVPEILN 654
GPPG P V+ S+ + W +G PI + I+ R W + +P+ ++
Sbjct: 1826 GPPGVPIIVRY----SSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVS 1881
Query: 655 GKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVP 700
T++ + L P V Y+FRV+A N G G PS PS+ + + + P
Sbjct: 1882 SYTFSMDI--LKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
>gi|28373124 contactin 4 isoform b precursor [Homo sapiens]
Length = 282
Score = 300 bits (769), Expect = 4e-81
Identities = 144/254 (56%), Positives = 186/254 (73%), Gaps = 1/254 (0%)
Query: 748 WSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPR 807
W ++S ++SR+V+RNES+ P SPFEVKVGV+NN+GEG S T+VYS E+EP P
Sbjct: 3 WMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPA 62
Query: 808 GTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTKNIT 867
+S SA+++EV W A +N GR+ GYEV YW + KE KIR GN T+ IT
Sbjct: 63 SIFARSLSATDIEVFW-ASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKIT 121
Query: 868 GLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVK 927
LK + +Y +V+AYN+AGTGPSS VNVTT+K PPSQPP NI W ++SK+ LNW+ VK
Sbjct: 122 NLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVK 181
Query: 928 TMENESEVLGYKILYRQNRQSKTHILETNNTSAELLVPFEEDYLIEIRTVSDGGDGSSSE 987
++NESEV GYK+LYR NRQS T ++ETN TS EL +PF+EDY+IEI+ SDGGDGSSSE
Sbjct: 182 ALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSE 241
Query: 988 EIRIPKMSSLSSRG 1001
+IRIPK+S+ +RG
Sbjct: 242 QIRIPKISNAYARG 255
Score = 44.3 bits (103), Expect = 6e-04
Identities = 49/203 (24%), Positives = 89/203 (43%), Gaps = 28/203 (13%)
Query: 597 PPGPPEDVQVEDISSTTSQLSWRAGP--DNNSPIQIFTIQ--TRTPFSVGWQAVATVPEI 652
P PP + +S+T ++ W A P N IQ + ++ + + TV
Sbjct: 57 PTKPPASIFARSLSATDIEVFW-ASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTV--- 112
Query: 653 LNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGG 712
G + + L V Y V A NS G G PS + + T+ P P NI
Sbjct: 113 --GNQTSTKITNLKGSVLYHLAVKAYNSAGTG-PSSATVNVTTRKPPPSQPPGNII-WNS 168
Query: 713 SRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLS 772
S S++++ W+ + E GY +++R W+++ +SV + N++ + LS
Sbjct: 169 SDSKIILNWDQVKALDNESEVKGYKVLYR------WNRQSSTSV-----IETNKTSVELS 217
Query: 773 -PFE----VKVGVYNNEGEGSLS 790
PF+ +++ +++ G+GS S
Sbjct: 218 LPFDEDYIIEIKPFSDGGDGSSS 240
>gi|237858675 neurofascin isoform 1 precursor [Homo sapiens]
Length = 1240
Score = 298 bits (762), Expect = 2e-80
Identities = 246/909 (27%), Positives = 391/909 (43%), Gaps = 68/909 (7%)
Query: 43 KSEVILNCAANGYPSPHYRWKQNGTDIDFTMS--YHYRLDGGSLAIN---SPHTDQDIGM 97
+ +++ C A G P+P + W +N + R G+L I+ ++ G
Sbjct: 56 RDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 115
Query: 98 YQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAW 157
YQC A N GT LS + +LQ + + + V V+EG + L C PPP W
Sbjct: 116 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 175
Query: 158 TFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVG-NYTCFITNKEAQRSVQGPPTPLVQ 216
+ Q+ +R G+LY + V D+ +Y+C Q P L
Sbjct: 176 MSSSMEPITQD--KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKV 233
Query: 217 RTDGVMGEYEPKIEVRFPETIQAA----KDSSVKLECFALGNPVPDISWRRLDGSPLPGK 272
T + E P +P+ ++ + + LEC A G P PDI+W + G K
Sbjct: 234 LTTRGVAERTPSF--MYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDK 291
Query: 273 VKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIY 332
K+ L I N +ED G Y C+ASN G + A P W + +N L+
Sbjct: 292 AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPG 351
Query: 333 DNLLWECKASGKPNPWYTWLKNGERLN---PEERIQIENGTLIITMLNVSDSGVYQCAAE 389
++ C+A+G P P W+ NGE L P ++ T+I +S VYQC
Sbjct: 352 EDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTS 411
Query: 390 NKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISW-KRGTE 448
N++ + ANA + VL P SP + V + + C P + W K G
Sbjct: 412 NEHGYLLANAFVSVL-DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG 470
Query: 449 TLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSK 508
+ + E+GSL+I I + D G YTC+ATN G A+N L VK+ T I P
Sbjct: 471 SNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPED 530
Query: 509 MDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQ 568
G ++ L C+V HDPS+++ W + + + + + + L I +
Sbjct: 531 QVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-------KEDDSLTIFGVA 583
Query: 569 LHHSGKYLCTVQTTLES------LSAVAD---------IIVRGPPGPPEDVQVEDISSTT 613
G Y C T L+ L+ +AD + +G P P D+++ D++ +
Sbjct: 584 ERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERS 643
Query: 614 SQLSWRAGPDNNSPIQIFTIQ-TRTPFSVG-WQAVATVPEILNGKTYNATVVGLSPWVEY 671
+L+W G NNSPI + +Q F G W + P + N+ V+ LSP+V Y
Sbjct: 644 VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP-----GSVNSAVLRLSPYVNY 698
Query: 672 EFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNG 731
+FRV+A N +G PS PSE RT + P P ++ G G ++ + ITW + G
Sbjct: 699 QFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFG 758
Query: 732 EGFGYIIMFRPVGS-TTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLS 790
YI+ +R + W+ +V SR+V + P+E++V N+ G+G
Sbjct: 759 PNLRYIVKWRRRETREAWNN---VTVWGSRYVVGQTPV--YVPYEIRVQAENDFGKGPEP 813
Query: 791 TVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKES 850
I YSGED P APR ++ + + + W+ G ++GY + Y + +
Sbjct: 814 ESVIGYSGEDLPS-APRRFRVRQPNLETINLEWDHP--EHPNGIMIGYTLKYVAFNG--T 868
Query: 851 MIGKIRV---SGNVTTKNITGLKANTIYFASVRAYNTAGTGPS------SPPVNVTTKKS 901
+GK V S N T + + Y ++ A G+G + +PP T +
Sbjct: 869 KVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAA 928
Query: 902 PPSQPPANI 910
PP+ PP +
Sbjct: 929 PPTLPPTTV 937
Score = 108 bits (271), Expect = 2e-23
Identities = 172/779 (22%), Positives = 281/779 (36%), Gaps = 82/779 (10%)
Query: 181 LYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAA 240
L I V D G Y C +NK ++ T V + P + P+ + A
Sbjct: 301 LRITNVSEEDSGEYFCLASNKMGS----------IRHTISVRVKAAP-YWLDEPKNLILA 349
Query: 241 KDSSVKLECFALGNPVPDISWRRLDGSPL---PGKVKYSKSQAILEIPNFQQEDEGFYEC 297
+L C A GNP P + W ++G PL P + + + Q Y+C
Sbjct: 350 PGEDGRLVCRANGNPKPTVQWM-VNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQC 408
Query: 298 IASNLRGRNLAKGQL-IFYAPPEW-EQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNG 355
SN G LA + + PP + Q + +Y+ +C G P P W KNG
Sbjct: 409 NTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG 468
Query: 356 ERLNPE--ERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKS 413
+ N + ENG+L I M+ D G+Y C A N I AE +V D ++
Sbjct: 469 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATN----ILGKAENQVRLEVKDPTRI 524
Query: 414 -PVKKKSFVQVGGDIVIGCKPNAFP--RAAISWKRGTETLRQSKRIFLLEDGSLKIYNIT 470
+ + + G + + C+ P + +SW + E L R+ ED SL I+ +
Sbjct: 525 YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRM-KKEDDSLTIFGVA 583
Query: 471 RSDAGSYTCIATNQFGT--AKNTGSLIVKERT----VITVPPSKMD-------VTVGESI 517
D GSYTC+A+ + AK +++ + T + +P + D + E
Sbjct: 584 ERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERS 643
Query: 518 VLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLC 577
V + D + + + + + GV H SV ++R + +
Sbjct: 644 VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVI 703
Query: 578 TVQTTLESLSAVADIIVRGPPGPPE----DVQVEDISSTTSQLSWRAGPDNNSPIQIFTI 633
+ S ++ R PPE DV+ E +++W P N +
Sbjct: 704 AINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWT--PMNATS----AF 757
Query: 634 QTRTPFSVGWQAVATVPEILNGKTYNAT-VVGLSP-WVEYEFRVVAGNSIGIGEPSEPSE 691
+ V W+ T N + + VVG +P +V YE RV A N G G EP
Sbjct: 758 GPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGP--EPES 815
Query: 692 LLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKE 751
++ AP + + + W+ E NG GY + + T K+
Sbjct: 816 VIGYSGEDLPSAPRRFRVRQPNLETINLEWDH--PEHPNGIMIGYTLKYVAFNGTKVGKQ 873
Query: 752 KVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTV-TIVYSGEDEPQLAPRGTS 810
V + ++ + + P+S + + G G T + E P AP
Sbjct: 874 IVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAPPTLP 933
Query: 811 LQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTKNITGLK 870
+ A+ S +A A + T+ + +I + + TT +
Sbjct: 934 PTTVGATGAVSSTDATA------------IAATTEATTVPIIPTVAPTTIATTTTVATTT 981
Query: 871 ANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLT---NSKLC-LNWEH 925
T A T SPP + K S P W +T NSK + W+H
Sbjct: 982 TTTA---------AATTTTESPPTTTSGTKIHESAPDEQSIWNVTVLPNSKWANITWKH 1031
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 290 bits (742), Expect = 5e-78
Identities = 280/1012 (27%), Positives = 445/1012 (43%), Gaps = 74/1012 (7%)
Query: 5 WKLVIL-LPLINSSAGDGLLSRPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWK 63
W L+ L L L+ + A D + P F EP + + L + ++L C A G ++W
Sbjct: 84 WALLALQLHLLRALAQDDVA--PYFKTEPG--LPQIHLEGNRLVLTCLAEGSWPLEFKWM 139
Query: 64 QNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIED 123
++ +++ T S Y+ SL D G Y+C+ N +G +L RK+++Q AY+
Sbjct: 140 RDDSELT-TYSSEYKYIIPSLQ------KLDAGFYRCVVRNRMGALLQRKSEVQVAYMGS 192
Query: 124 F-ETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLY 182
F +T R TVS +G+ +L P + W + + NR ++ E L
Sbjct: 193 FMDTDQRKTVS--QGRAAILNLLPITSYPRPQVTWFREGHKII--PSNRIAITLEN-QLV 247
Query: 183 IAKVEPSDVGNYTCFITNKEAQRSVQGPPTPL-VQRTDGVMGEYEPKIEVRFPETIQAAK 241
I SD G Y N++ + P L + R G P I V A
Sbjct: 248 ILATTTSDAGAYYVQAVNEKNGENKTSPFIHLSIARDVGTPETMAPTIVVPPGNRSVVAG 307
Query: 242 DSSVKLECFALGNPVPDIS--WRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIA 299
S LEC A PV D+S W+R G + + L I N D G Y C A
Sbjct: 308 SSETTLECIASARPVEDLSVTWKRNGVRITSGLHSFGRR---LTISNPTSADTGPYVCEA 364
Query: 300 SNLRGRNL----AKGQLIFYAPPEWEQKIQNT-HLSIYDNLLWECKASGKPNPWYTWLKN 354
+ L G A L PP + + ++ + + + C+A G P P W K+
Sbjct: 365 A-LPGSAFEPARATAFLFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKD 423
Query: 355 GERL----NPEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDF 410
+ NP ++ + +G L I L DSG++QC A N+ I + L V AP F
Sbjct: 424 AISISRLQNPRYKV-LASGGLRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVF 482
Query: 411 SKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSK----RIFLLEDGSLKI 466
++ PV + V G ++ C+ + P+ AI+WKR L R LLE G L+I
Sbjct: 483 TQRPVD--TTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQI 540
Query: 467 YNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHD 526
+ DAG+YTC A N G+ + +L V RT I PP V G + L C +HD
Sbjct: 541 APVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHD 600
Query: 527 PSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESL 586
P + + +VW D + L + RI E G L+I G Y C + + +
Sbjct: 601 PRVSLRYVW--KKDNVALTP--SSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGND 656
Query: 587 SAVADIIVRGPPGPPEDVQVEDISSTTSQ--LSWRAGPDNNSPIQIFTI---QTRTPFSV 641
S +A + V P P+++ V SS + LSW D NSPI + + + +P+ V
Sbjct: 657 SRMARLEVIELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIVELSENNSPWKV 716
Query: 642 GWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPV 701
V PE+ TV GL+P Y+FRV A N +G G+ S + L P
Sbjct: 717 HLSNVG--PEMT-----GVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPS 769
Query: 702 VAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVG-STTWSKEKVSSVESSR 760
P NI G + +++ W+ PE NG GYI+ +R G + + ++S E +
Sbjct: 770 APPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNY 829
Query: 761 FVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEME 820
+ + +I + +E++V YN G G S Y+ + P P+ ++ +++ ++
Sbjct: 830 CLVTD--LIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQ 887
Query: 821 VSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGN---VTTKNITGLKANTIYFA 877
WN G GY++L W D+ E+ + + ++ + V +IT LK T YF
Sbjct: 888 FLWNPPPQQFINGINQGYKLLAWPADAPEA-VTVVTIAPDFHGVHHGHITNLKKFTAYFT 946
Query: 878 SVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLG 937
SV + T G GP S P V T++ P ++ ++ L ++W+ + +E + G
Sbjct: 947 SVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQ--EPLEKNGIITG 1004
Query: 938 YKI---LYRQNRQSKTHILETNNTSAELLVPFEED---YLIEIRTVSDGGDG 983
Y+I +Y +N TH L N+T+ E + Y I++ V+ G G
Sbjct: 1005 YQISWEVYGRNDSRLTHTL--NSTTHEYKIQGLSSLTTYTIDVAAVTAVGTG 1054
Score = 129 bits (324), Expect = 1e-29
Identities = 103/374 (27%), Positives = 167/374 (44%), Gaps = 34/374 (9%)
Query: 595 RGPPGPPEDVQVE--DISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEI 652
R P PP ++ V ++++ + +L W G D SPI+ FT+Q R WQ T
Sbjct: 1474 RERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQ---TYSSS 1530
Query: 653 LNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGG 712
++ + V L P+ Y+ R+ A N IG + S +E + T VP P ++
Sbjct: 1531 ISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPH 1590
Query: 713 SRSELVITWESIPEELQNGEGFGYIIMFRPV----GSTTWSKEKVSSVE-------SSRF 761
+ S ++I W+ +E NG GY I +R + GS T +K + + S F
Sbjct: 1591 TTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSF 1650
Query: 762 VYRNES----------IIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSL 811
N S + +EV + YN GE S V+ GE P +AP+ +
Sbjct: 1651 KTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQV 1710
Query: 812 QSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSK---ESMIGKIRVSGNVTTKNITG 868
+AS++EV+W+ G + GY++ YW DS+ E M V KN+T
Sbjct: 1711 TPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLT- 1769
Query: 869 LKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKT 928
++T Y S+ A+N AG GP S P T ++ P P ++T++ L ++W
Sbjct: 1770 --SHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAA 1827
Query: 929 MENESEVLGYKILY 942
+ GY+++Y
Sbjct: 1828 ANGILQ--GYRVVY 1839
Score = 108 bits (271), Expect = 2e-23
Identities = 88/371 (23%), Positives = 164/371 (44%), Gaps = 11/371 (2%)
Query: 579 VQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTP 638
V T L + S ++ + PG P ++ + +IS ++ L +R G D + I + ++ +
Sbjct: 1051 VGTGLVTSSTISSGVPPDLPGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVG 1110
Query: 639 FSVGWQAVATVPEILNGKTYNATVV-GLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKA 697
+ T+ E N + L+P+ Y FR+ N +G S S +++T
Sbjct: 1111 AIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQ 1170
Query: 698 SVPVVAPVNIHGGGGSRSELVITWESIPEELQNG--EGFGYIIMFRPVGSTTWSKEKVSS 755
+ P VAP ++ S + L + W +P+ NG E GY I + + V+
Sbjct: 1171 APPDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKY---WRSDLQSSAVAQ 1227
Query: 756 VESSRFV--YRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQS 813
V S R + E + +E+++ +N G G S V + E P AP S ++
Sbjct: 1228 VVSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEA 1287
Query: 814 FSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTKNITGLKANT 873
S++++ ++W ++ G +LGY++L+ D I + + + GL+
Sbjct: 1288 VSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALLAGLRKFV 1347
Query: 874 IYFASVRAYNTAGTG-PSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTMENE 932
+Y V A+ G G PS+P + TK P P + ++ + + + W+ + E
Sbjct: 1348 LYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPE--EPN 1405
Query: 933 SEVLGYKILYR 943
+LGY+I YR
Sbjct: 1406 GIILGYQIAYR 1416
Score = 97.1 bits (240), Expect = 8e-20
Identities = 100/423 (23%), Positives = 164/423 (38%), Gaps = 39/423 (9%)
Query: 587 SAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGW--- 643
S V + P P V V S T+ +L W PD+ P SVG+
Sbjct: 1163 SRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQ--------YNGNPESVGYRIK 1214
Query: 644 ------QAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKA 697
Q+ A + + T+ L W+EYE ++ A N++G G SE RT+
Sbjct: 1215 YWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRG-RTRE 1273
Query: 698 SVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKV---S 754
SVP AP N+ S +++++TW S+PE+ QNG GY I+FR + + +
Sbjct: 1274 SVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGN 1333
Query: 755 SVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSF 814
+S+ + ++ +E++V + G G ST I+ +D+ P
Sbjct: 1334 HTQSALLAGLRKFVL----YELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEV 1389
Query: 815 SASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTKNITGLKANTI 874
+ + + W G +LGY++ Y S + V V T L +
Sbjct: 1390 RLTSVRIVWQPP--EEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESA 1447
Query: 875 YFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANI---AWKLTNSKLCLNWEHVKTMEN 931
Y + A G G +TT+K PP + ++T L L W V +
Sbjct: 1448 YIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQW--VPGSDG 1505
Query: 932 ESEVLGYKILYRQ------NRQSKTHILETNNTSAELLVPFEEDYLIEIRTVSDGGDGSS 985
S + + + R+ S + E + L PF Y + ++ +D GD
Sbjct: 1506 ASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPF-TSYKLRLKATNDIGDSDF 1564
Query: 986 SEE 988
S E
Sbjct: 1565 SSE 1567
Score = 83.2 bits (204), Expect = 1e-15
Identities = 95/372 (25%), Positives = 154/372 (41%), Gaps = 37/372 (9%)
Query: 593 IVRG------PPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAV 646
+VRG P PE+V E +SST L+W + P+ + I + + ++A
Sbjct: 1266 VVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILG------YKILFRAK 1319
Query: 647 ATVPE-----ILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPV 701
PE + T +A + GL +V YE +V+A IG G PS P L RTK P
Sbjct: 1320 DLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPG 1379
Query: 702 VAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRF 761
PV + + + I W+ P E NG GY I +R S S ++VE
Sbjct: 1380 -PPVRLVFPEVRLTSVRIVWQ--PPEEPNGIILGYQIAYRLASS---SPHTFTTVEVGAT 1433
Query: 762 V--YRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEM 819
V + + P S + ++ +G G T++ + + E PR +
Sbjct: 1434 VRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPR-----ELLVPQA 1488
Query: 820 EVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIR-----VSGNVTTKNITGLKANTI 874
EV+ ++ G + Y+T +E G+ + +S T + L+ T
Sbjct: 1489 EVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTS 1548
Query: 875 YFASVRAYNTAGTGP-SSPPVNVTTKKSPPSQPPANI-AWKLTNSKLCLNWEHVKTMENE 932
Y ++A N G SS VTT + P +PP ++ A T S + + W+ +
Sbjct: 1549 YKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLN 1608
Query: 933 SEVLGYKILYRQ 944
+ GY+I YR+
Sbjct: 1609 GLLQGYRIYYRE 1620
Score = 57.0 bits (136), Expect = 9e-08
Identities = 52/179 (29%), Positives = 74/179 (41%), Gaps = 24/179 (13%)
Query: 523 VSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTT 582
VS ++EV W V DL KGV +F R+ ++ Y +Q
Sbjct: 1848 VSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTI--------------TYGPELQAN 1893
Query: 583 LESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVG 642
+ + A G PG P DV V +S + L W G ++P + I+ R
Sbjct: 1894 ITAGPA------EGSPGSPRDVLVTKSASELT-LQWTEGHSGDTPTTGYVIEARPSDEGL 1946
Query: 643 WQA-VATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVP 700
W V +P + +Y ++ L V YEFRVVA N G GEPS PS + + P
Sbjct: 1947 WDMFVKDIPR--SATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAP 2003
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 213 bits (542), Expect = 7e-55
Identities = 235/1006 (23%), Positives = 411/1006 (40%), Gaps = 88/1006 (8%)
Query: 44 SEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLAT 103
S+V L+C+ G W +NG ++ + I D G YQC
Sbjct: 329 SQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVR 388
Query: 104 NLLGTILSRKAKLQFAYIEDFETKTRSTVS---VREGQGVVLLCG----PPPHFGDLSYA 156
LS + +Q +ED K S S V + V L+C P P +
Sbjct: 389 K---DKLSAQDYVQVV-LEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLP-----TIT 439
Query: 157 WTFNDNPLYVQEDNR--RFVSQETGN----LYIAKVEPSDVGNYTCFITNKEAQRSVQGP 210
WT +D+P+ +R + ++ E GN L I+ + D G Y C N
Sbjct: 440 WTLDDDPILKGGSHRISQMITSE-GNVVSYLNISSSQVRDGGVYRCTANNSA-------- 490
Query: 211 PTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSV------KLECFALGNPVPDISWRRL 264
GV+ Y+ +I VR P +I+ K+ + + C +G P I W +
Sbjct: 491 ---------GVV-LYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKN 540
Query: 265 DGS-PLPGKVKYSKSQAILEIPNFQQE-DEGFYECIASNLRGRNLAKGQLIFYAPPEWEQ 322
P + ++ L++ + Q+E DEG Y C + ++ + P + Q
Sbjct: 541 SNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQ 600
Query: 323 KIQNTHLSIYDNLLWECKA-SGKPNPWYTWLKNGERLNPEERIQIEN----GTLIITMLN 377
+ SI + C SG TW K+G + + I+N +L I+ L+
Sbjct: 601 PFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLS 660
Query: 378 VSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFP 437
+ +G Y C A N+ + ++L ++ P F P + G +++ C +P
Sbjct: 661 LMHNGNYTCIARNEAAAVEHQSQL-IVRVPPKFVVQPRDQDGIY--GKAVILNCSAEGYP 717
Query: 438 RAAISWK--RGT-----ETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGT-AK 489
I WK +G + + + RI +L +GSL I ++ D+G Y C +N G
Sbjct: 718 VPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVS 777
Query: 490 NTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVI--DLKKG 547
+ L VK +IT P+ T G+ + C + I + W +I ++ +
Sbjct: 778 KSMYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPI--IVRWEKEDRIINPEMARY 835
Query: 548 VAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVE 607
+ + +G E + L I SG + C + + + V+ PP PPE ++++
Sbjct: 836 LVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPE-IEIK 894
Query: 608 DISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSP 667
D+ + T L W G D NSPI + I+ + S W + ++ + + +AT++ + P
Sbjct: 895 DVKARTITLRWTMGFDGNSPITGYDIECKNK-SDSWDSAQRTKDV-SPQLNSATIIDIHP 952
Query: 668 WVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEE 727
Y R+ A N IG EPS + +A+ P P +H S + +TW++ +
Sbjct: 953 SSTYSIRMYAKNRIGKSEPSNELTITADEAA-PDGPPQEVHLEPISSQSIRVTWKAPKKH 1011
Query: 728 LQNGEGFGYIIMFRPVGSTTWSKEKVSSVESS--RFVYRNESIIPLSPFEVKVGVYNNEG 785
LQNG GY I +R + + + SV++S VY +++ + + + V N G
Sbjct: 1012 LQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAG 1071
Query: 786 EGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTD 845
G S I + ED P P + S + +SW+ ++ G + G+ V+YW +
Sbjct: 1072 TGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWAN 1131
Query: 846 DSKESMIGKIRVSGNVTTK----NITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKS 901
M G++ N+TT + GL+ T Y V A+ AG G S + TK+
Sbjct: 1132 ----LMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKED 1187
Query: 902 PPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSAE 961
P P A + S + ++W + ++ + Y + + E + S
Sbjct: 1188 VPGPPAGVKAAAASASMVFVSW--LPPLKLNGIIRKYTVFCSHPYPTVISEFEASPDSFS 1245
Query: 962 LLVP---FEEDYLIEIRTVSDGGDGSSSEEIRIPKMSSLSSRGIQF 1004
+P Y + + V+ G G+SSE I + ++ +R + F
Sbjct: 1246 YRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPLAKAPARILTF 1291
Score = 167 bits (423), Expect = 5e-41
Identities = 235/1008 (23%), Positives = 384/1008 (38%), Gaps = 123/1008 (12%)
Query: 41 LSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQC 100
++ V L C A G+P P YRW ++ ++ + + + G + P D G Y C
Sbjct: 237 MAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRP---SDSGSYVC 293
Query: 101 LATNLLGT--ILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWT 158
+N GT ++ R Q K +S+V G V L C D +W
Sbjct: 294 EVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSV----GSQVSLSCSVTGT-EDQELSW- 347
Query: 159 FNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKE--AQRSVQGPPTPLVQ 216
+ + + N R NL + + SD G Y CF+ + AQ VQ V
Sbjct: 348 YRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQ------VV 401
Query: 217 RTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYS 276
DG PKI F E + + + V L C G P+P I+W LD P+ +
Sbjct: 402 LEDGT-----PKIISAFSEKVVSPAEP-VSLMCNVKGTPLPTITWT-LDDDPILKGGSHR 454
Query: 277 KSQAI---------LEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNT 327
SQ I L I + Q D G Y C A+N G L + ++ P T
Sbjct: 455 ISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKNIT 514
Query: 328 HLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQI---ENGTLIITMLNVS-DSGV 383
++ D + C+ G P W KN L P Q+ NGTL ++ + D G
Sbjct: 515 AIAGRDTYI-HCRVIGYPYYSIKWYKNSNLL-PFNHRQVAFENNGTLKLSDVQKEVDEGE 572
Query: 384 YQCAAENKYQI-----IYANAELRVLASAPDFSKSPVKKKSFVQ---VGGDIVIGCKPNA 435
Y C + Q+ ++ ++ +F + + ++ F+ V GD+ I
Sbjct: 573 YTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPI------ 626
Query: 436 FPRAAISWKRGTETLRQSKRIFLLE---DGSLKIYNITRSDAGSYTCIATNQFGTAKNTG 492
I+W++ + S + + SL+I N++ G+YTCIA N+ ++
Sbjct: 627 ----TITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQS 682
Query: 493 SLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFE 552
LIV+ V P D G++++L C P +V+ F G + + +A
Sbjct: 683 QLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWK-FSKGAGVPQFQPIALNG 741
Query: 553 RIGGESVGDLMIRNIQLHHSGKYLCTVQTTL-ESLSAVADIIVRGPPGPPEDVQVEDISS 611
RI S G L+I+++ SG YLC V + +S + V+ P +
Sbjct: 742 RIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIP------------AM 789
Query: 612 TTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATV--PE----ILNGKTYNATVVG- 664
TS + T P V W+ + PE +++ K V+
Sbjct: 790 ITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVIST 849
Query: 665 --LSPWVEYE---FRVVAGNSIG---------IGEPSEPSELLRTKASVPVVAPVNIHGG 710
+ P V + F A NS G + EP +P E+ + G
Sbjct: 850 LQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEIEIKDVKARTITLRWTMGF 909
Query: 711 GGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIP 770
G N GY I + + S ++ V I P
Sbjct: 910 DG-----------------NSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHP 952
Query: 771 LSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNR 830
S + +++ N G+ S + + E P P+ L+ S+ + V+W A +
Sbjct: 953 SSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHL 1012
Query: 831 NTGRVLGYEV---LYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGT 887
G + GY++ Y T + + I + SG+ + L T Y V+A N AGT
Sbjct: 1013 QNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGT 1072
Query: 888 GPSSPPVNVTTKKSPPSQPPANI-AWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQN- 945
GPSS + TT + PS PP N+ A + + ++W + + G++++Y N
Sbjct: 1073 GPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANL 1132
Query: 946 ---RQSKTHILETNNTSAEL-LVPFEEDYLIEIRTVSDGGDGSSSEEI 989
+ + T S EL + +Y I++ + GDG SE+I
Sbjct: 1133 MDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQI 1180
Score = 119 bits (297), Expect = 2e-26
Identities = 141/607 (23%), Positives = 241/607 (39%), Gaps = 59/607 (9%)
Query: 27 IFTQEPHDVIFPLDLSKSEVI--------LNCAANGYPSPHYRWK-QNGTDIDFTMSYHY 77
+F+++ H ++ ++ S EV+ + C A G P RW G +I +
Sbjct: 15 VFSEDLHSSLYFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYLATGEEIYDVPGIRH 74
Query: 78 RLDGGSLAI-----NSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTV 132
G+L I +S T Y C A N G I S+ ++ E + +
Sbjct: 75 VHPNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIRSQDVHIKAVLREPYTVRVEDQK 134
Query: 133 SVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSD-V 191
++R G V C P ++ + + + +R F+ TG LYI V+ D +
Sbjct: 135 TMR-GNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSR-FLITSTGALYIKDVQNEDGL 192
Query: 192 GNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFA 251
NY C ++ + Q L P I F +A V+L C A
Sbjct: 193 YNYRCITRHRYTGETRQSNSARLFVSDPA---NSAPSILDGFDHR-KAMAGQRVELPCKA 248
Query: 252 LGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQ 311
LG+P PD W + D PL ++ K+ L I N + D G Y C SN G G+
Sbjct: 249 LGHPEPDYRWLK-DNMPLELSGRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGR 307
Query: 312 LIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQ---IEN 368
L P + + S+ + C +G + +W +NGE LNP + ++ I +
Sbjct: 308 LYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINH 367
Query: 369 GTLIITMLNVSDSGVYQC-------AAENKYQIIYANAELRVLASAPDFSKSPVKKKSFV 421
LI+ + SD G YQC +A++ Q++ + +++++ + SP + S +
Sbjct: 368 ENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLM 427
Query: 422 QVGGDIVIGCKPNAFPRAAISWKRGTETLRQ--SKRI--FLLEDGSLKIY-NITRS---D 473
C P I+W + + + S RI + +G++ Y NI+ S D
Sbjct: 428 ---------CNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRD 478
Query: 474 AGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVF 533
G Y C A N G + V+ I P + G + C+V P +
Sbjct: 479 GGVYRCTANNSAGVVLYQARINVRGPASIR-PMKNITAIAGRDTYIHCRVIGYPYYSI-- 535
Query: 534 VWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLH-HSGKYLCTVQTTLE-SLSAVAD 591
W+ N +++ + ++ E+ G L + ++Q G+Y C V + S S
Sbjct: 536 KWYKNSNLLPF-----NHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVH 590
Query: 592 IIVRGPP 598
+ V+ PP
Sbjct: 591 VTVKVPP 597
Score = 77.0 bits (188), Expect = 8e-14
Identities = 98/392 (25%), Positives = 154/392 (39%), Gaps = 49/392 (12%)
Query: 240 AKDSSVKLECFALGNPVPDISWRRLDGSPL---PGKVKYSKSQAILEIPNFQQED----- 291
A + + C A G P + W G + PG +++ L+I F
Sbjct: 37 ASTTGTLVPCPAAGIPPVTLRWYLATGEEIYDVPG-IRHVHPNGTLQIFPFPPSSFSTLI 95
Query: 292 -EGFYECIASNLRGRNLAKGQLIF------YAPPEWEQKIQNTHLSIYDNLLWECKASGK 344
+ Y C A N G+ ++ I Y +QK +++++ +C
Sbjct: 96 HDNTYYCTAENPSGKIRSQDVHIKAVLREPYTVRVEDQKTMRGNVAVF-----KCIIPSS 150
Query: 345 PNPWYT---WLKNGERLNPEERIQIEN-GTLIITMLNVSDSGV-YQCAAENKYQIIYANA 399
+ T W K+ L R I + G L I + D Y+C ++Y
Sbjct: 151 VEAYITVVSWEKDTVSLVSGSRFLITSTGALYIKDVQNEDGLYNYRCITRHRY-----TG 205
Query: 400 ELRVLASAPDFSKSPVKKKSFVQVGGD---------IVIGCKPNAFPRAAISWKRGTETL 450
E R SA F P + G D + + CK P W + L
Sbjct: 206 ETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPL 265
Query: 451 RQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMD 510
S R G L I NI SD+GSY C +N++GTAK G L VK+ T+ P K+
Sbjct: 266 ELSGRFQKTVTGLL-IENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVK 324
Query: 511 VTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLH 570
+VG + L C V+ E+ W+ NG++++ K V RI G + +L++ ++
Sbjct: 325 SSVGSQVSLSCSVTGTEDQEL--SWYRNGEILNPGKNV----RITGINHENLIMDHMVKS 378
Query: 571 HSGKYLCTVQTTLESLSAVADIIVRGPPGPPE 602
G Y C V+ + LSA + V G P+
Sbjct: 379 DGGAYQCFVRK--DKLSAQDYVQVVLEDGTPK 408
Score = 69.3 bits (168), Expect = 2e-11
Identities = 85/363 (23%), Positives = 153/363 (42%), Gaps = 52/363 (14%)
Query: 463 SLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVG-------E 515
S +I N++R+ S +A G ++ + V+ + P+++ G +
Sbjct: 1245 SYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEP---LAKAPARILTFSGTVTTPWMK 1301
Query: 516 SIVLPCQVSHDPSIEVVFVWFFNGD----VIDLKKGVAHFERIGGESVGDLMIRNIQLHH 571
IVLPC+ DPS V ++ NG ID ++ + S G +IR ++
Sbjct: 1302 DIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIF--------SNGSFIIRTVKAED 1353
Query: 572 SGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIF 631
SG Y C S + ++ V+ PP P + V +S++ LSW G + S I+ +
Sbjct: 1354 SGYYSCIANNNWGSDEIILNLQVQVPPDQPR-LTVSKTTSSSITLSWLPGDNGGSSIRGY 1412
Query: 632 TIQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSE 691
+Q S W + P + ++Y + W Y+F + A N +G G SE E
Sbjct: 1413 ILQYSEDNSEQWGSFPISP---SERSYRLENLKCGTW--YKFTLTAQNGVGPGRISEIIE 1467
Query: 692 LLRTKASVP-------VVAPVNIHGGGGSRSEL-VITWESIPEELQNGEGFGYIIMFRPV 743
+T P + A +N +R L +I W + + + + +RP
Sbjct: 1468 -AKTLGKEPQFSKEQELFASINT-----TRVRLNLIGWNDGGCPITS-----FTLEYRPF 1516
Query: 744 GSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEG--EGSLSTVTIVYSGEDE 801
G+T W+ + +S+ S +Y + + +E+++ V N+ G E + T+ Y G
Sbjct: 1517 GTTVWTTAQRTSLSKSYILY---DLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTI 1573
Query: 802 PQL 804
P L
Sbjct: 1574 PPL 1576
Score = 46.6 bits (109), Expect = 1e-04
Identities = 68/277 (24%), Positives = 109/277 (39%), Gaps = 37/277 (13%)
Query: 426 DIVIGCKPNAFPRAAISWKR---GTETLRQ-SKRIFLLEDGSLKIYNITRSDAGSYTCIA 481
DIV+ CK P A+ W + GT +L R + +GS I + D+G Y+CIA
Sbjct: 1302 DIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIA 1361
Query: 482 TNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDV 541
N +G+ + +L V+ VPP + +TV ++ SI + ++ NG
Sbjct: 1362 NNNWGSDEIILNLQVQ------VPPDQPRLTVSKTT--------SSSITLSWLPGDNGG- 1406
Query: 542 IDLKKGVAHFERIGGESVGDLMI---------RNIQLHHSGKYLCTVQTTLE----SLSA 588
++ + + E G I N++ K+ T Q + S
Sbjct: 1407 SSIRGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEII 1466
Query: 589 VADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVAT 648
A + + P E I++T +L+ D PI FT++ R PF G T
Sbjct: 1467 EAKTLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYR-PF--GTTVWTT 1523
Query: 649 VPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGE 685
K+Y + + W E + RV NS G E
Sbjct: 1524 AQRTSLSKSYILYDLQEATWYELQMRVC--NSAGCAE 1558
Score = 40.4 bits (93), Expect = 0.009
Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 6/92 (6%)
Query: 233 FPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNF----- 287
F T+ + L C A+G+P P + W + D + P V ++I +F
Sbjct: 1291 FSGTVTTPWMKDIVLPCKAVGDPSPAVKWMK-DSNGTPSLVTIDGRRSIFSNGSFIIRTV 1349
Query: 288 QQEDEGFYECIASNLRGRNLAKGQLIFYAPPE 319
+ ED G+Y CIA+N G + L PP+
Sbjct: 1350 KAEDSGYYSCIANNNWGSDEIILNLQVQVPPD 1381
Score = 40.4 bits (93), Expect = 0.009
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 7/93 (7%)
Query: 334 NLLWECKASGKPNPWYTWLKNGERLNPEERIQ-----IENGTLIITMLNVSDSGVYQCAA 388
+++ CKA G P+P W+K+ I NG+ II + DSG Y C A
Sbjct: 1302 DIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIA 1361
Query: 389 ENKY--QIIYANAELRVLASAPDFSKSPVKKKS 419
N + I N +++V P + S S
Sbjct: 1362 NNNWGSDEIILNLQVQVPPDQPRLTVSKTTSSS 1394
Score = 33.9 bits (76), Expect = 0.81
Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
Query: 45 EVILNCAANGYPSPHYRWKQ--NGTDIDFTMSYHYRL-DGGSLAINSPHTDQDIGMYQCL 101
+++L C A G PSP +W + NGT T+ + GS I + +D G Y C+
Sbjct: 1302 DIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKA-EDSGYYSCI 1360
Query: 102 ATNLLGT 108
A N G+
Sbjct: 1361 ANNNWGS 1367
>gi|237858682 neurofascin isoform 6 precursor [Homo sapiens]
Length = 613
Score = 198 bits (503), Expect = 2e-50
Identities = 155/568 (27%), Positives = 238/568 (41%), Gaps = 26/568 (4%)
Query: 43 KSEVILNCAANGYPSPHYRWKQNGTDIDFTMS--YHYRLDGGSLAIN---SPHTDQDIGM 97
+ +++ C A G P+P + W +N + R G+L I+ ++ G
Sbjct: 50 RDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 109
Query: 98 YQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAW 157
YQC A N GT LS + +LQ + + + V V+EG + L C PPP W
Sbjct: 110 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 169
Query: 158 TFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVG-NYTCFITNKEAQRSVQGPPTPLVQ 216
+ Q+ +R G+LY + V D+ +Y+C Q P L
Sbjct: 170 MSSSMEPITQD--KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKV 227
Query: 217 RTDGVMGEYEPKIEVRFPETIQAA----KDSSVKLECFALGNPVPDISWRRLDGSPLPGK 272
T + E P +P+ ++ + + LEC A G P PDI+W + G K
Sbjct: 228 LTTRGVAERTPSF--MYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDK 285
Query: 273 VKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIY 332
K+ L I N +ED G Y C+ASN G + A P W + +N L+
Sbjct: 286 AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPG 345
Query: 333 DNLLWECKASGKPNPWYTWLKNGERLN---PEERIQIENGTLIITMLNVSDSGVYQCAAE 389
++ C+A+G P P W+ NGE L P ++ T+I +S VYQC
Sbjct: 346 EDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTS 405
Query: 390 NKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISW-KRGTE 448
N++ + ANA + VL P SP + V + + C P + W K G
Sbjct: 406 NEHGYLLANAFVSVL-DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG 464
Query: 449 TLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSK 508
+ + E+GSL+I I + D G YTC+ATN G A+N L VK+ T I P
Sbjct: 465 SNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPED 524
Query: 509 MDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQ 568
G ++ L C+V HDPS+++ W + + + + + + L I +
Sbjct: 525 QVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-------KEDDSLTIFGVA 577
Query: 569 LHHSGKYLCTVQTTLESLSAVADIIVRG 596
G Y C T L+ A A + V G
Sbjct: 578 ERDQGSYTCVASTELDQDLAKAYLTVLG 605
Score = 90.9 bits (224), Expect = 6e-18
Identities = 93/377 (24%), Positives = 156/377 (41%), Gaps = 38/377 (10%)
Query: 45 EVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATN 104
+++L C A+G P+P W + G D+ + + N +++D G Y CLA+N
Sbjct: 257 DLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNV--SEEDSGEYFCLASN 314
Query: 105 LLGTI---LSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFND 161
+G+I +S + K +++ E K +G+ V G P + W N
Sbjct: 315 KMGSIRHTISVRVKAAPYWLD--EPKNLILAPGEDGRLVCRANGNPKP----TVQWMVNG 368
Query: 162 NPLYVQEDN-RRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDG 220
PL N R V+ +T + + S Y C +N+ + L
Sbjct: 369 EPLQSAPPNPNREVAGDT--IIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVL------ 420
Query: 221 VMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISW-RRLDGSPLPGKVKYSKSQ 279
+ P++ + I+ + +L+C G+P+P + W + GS L G +
Sbjct: 421 ---DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYEN 477
Query: 280 AILEIPNFQQEDEGFYECIASNLRG------RNLAKGQLIFYAPPEWEQKIQNTHLSIYD 333
LEI ++ED+G Y C+A+N+ G R K Y PE + + T + +
Sbjct: 478 GSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQL-- 535
Query: 334 NLLWECKASGKPNPWYT--WLKNGERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENK 391
EC+ P+ T WLK+ E L R++ E+ +L I + D G Y C A +
Sbjct: 536 ----ECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTE 591
Query: 392 YQIIYANAELRVLASAP 408
A A L VL + P
Sbjct: 592 LDQDLAKAYLTVLGNCP 608
Score = 79.3 bits (194), Expect = 2e-14
Identities = 82/295 (27%), Positives = 119/295 (40%), Gaps = 43/295 (14%)
Query: 333 DNLLWECKASGKPNPWYTWLKNGERLN----PEERIQIENGTLIITMLNVSD----SGVY 384
DN+L EC+A G P P + W +N N P ++ +GTL+I + G Y
Sbjct: 51 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 110
Query: 385 QCAAENKYQIIYANAELRVLASAPDFSKSPVKKKS-----FVQVGGDIVIGCKPN-AFPR 438
QC A NK+ +N +R+ SKSP+ K VQ G + + C P P
Sbjct: 111 QCFARNKFGTALSN-RIRL-----QVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPS 164
Query: 439 AAISWKRGT-ETLRQSKRIFLLEDGSLKIYNITRSDAGS-YTCIATNQFG---------T 487
I W + E + Q KR+ +G L N+ D + Y+C A F T
Sbjct: 165 PVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFT 224
Query: 488 AKNTGSLIVKERTVITVPP----SKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVID 543
K + V ERT + P S V G ++L C S P+ ++ W+ G D
Sbjct: 225 LKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIA--WYKKGG--D 280
Query: 544 LKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPP 598
L A FE L I N+ SG+Y C + S+ + V+ P
Sbjct: 281 LPSDKAKFENFNKA----LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAP 331
>gi|237858680 neurofascin isoform 5 precursor [Homo sapiens]
Length = 619
Score = 198 bits (503), Expect = 2e-50
Identities = 155/568 (27%), Positives = 238/568 (41%), Gaps = 26/568 (4%)
Query: 43 KSEVILNCAANGYPSPHYRWKQNGTDIDFTMS--YHYRLDGGSLAIN---SPHTDQDIGM 97
+ +++ C A G P+P + W +N + R G+L I+ ++ G
Sbjct: 56 RDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 115
Query: 98 YQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAW 157
YQC A N GT LS + +LQ + + + V V+EG + L C PPP W
Sbjct: 116 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 175
Query: 158 TFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVG-NYTCFITNKEAQRSVQGPPTPLVQ 216
+ Q+ +R G+LY + V D+ +Y+C Q P L
Sbjct: 176 MSSSMEPITQD--KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKV 233
Query: 217 RTDGVMGEYEPKIEVRFPETIQAA----KDSSVKLECFALGNPVPDISWRRLDGSPLPGK 272
T + E P +P+ ++ + + LEC A G P PDI+W + G K
Sbjct: 234 LTTRGVAERTPSF--MYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDK 291
Query: 273 VKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIY 332
K+ L I N +ED G Y C+ASN G + A P W + +N L+
Sbjct: 292 AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPG 351
Query: 333 DNLLWECKASGKPNPWYTWLKNGERLN---PEERIQIENGTLIITMLNVSDSGVYQCAAE 389
++ C+A+G P P W+ NGE L P ++ T+I +S VYQC
Sbjct: 352 EDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTS 411
Query: 390 NKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISW-KRGTE 448
N++ + ANA + VL P SP + V + + C P + W K G
Sbjct: 412 NEHGYLLANAFVSVL-DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG 470
Query: 449 TLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSK 508
+ + E+GSL+I I + D G YTC+ATN G A+N L VK+ T I P
Sbjct: 471 SNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPED 530
Query: 509 MDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQ 568
G ++ L C+V HDPS+++ W + + + + + + L I +
Sbjct: 531 QVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-------KEDDSLTIFGVA 583
Query: 569 LHHSGKYLCTVQTTLESLSAVADIIVRG 596
G Y C T L+ A A + V G
Sbjct: 584 ERDQGSYTCVASTELDQDLAKAYLTVLG 611
Score = 90.9 bits (224), Expect = 6e-18
Identities = 93/377 (24%), Positives = 156/377 (41%), Gaps = 38/377 (10%)
Query: 45 EVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATN 104
+++L C A+G P+P W + G D+ + + N +++D G Y CLA+N
Sbjct: 263 DLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNV--SEEDSGEYFCLASN 320
Query: 105 LLGTI---LSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFND 161
+G+I +S + K +++ E K +G+ V G P + W N
Sbjct: 321 KMGSIRHTISVRVKAAPYWLD--EPKNLILAPGEDGRLVCRANGNPKP----TVQWMVNG 374
Query: 162 NPLYVQEDN-RRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDG 220
PL N R V+ +T + + S Y C +N+ + L
Sbjct: 375 EPLQSAPPNPNREVAGDT--IIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVL------ 426
Query: 221 VMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISW-RRLDGSPLPGKVKYSKSQ 279
+ P++ + I+ + +L+C G+P+P + W + GS L G +
Sbjct: 427 ---DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYEN 483
Query: 280 AILEIPNFQQEDEGFYECIASNLRG------RNLAKGQLIFYAPPEWEQKIQNTHLSIYD 333
LEI ++ED+G Y C+A+N+ G R K Y PE + + T + +
Sbjct: 484 GSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQL-- 541
Query: 334 NLLWECKASGKPNPWYT--WLKNGERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENK 391
EC+ P+ T WLK+ E L R++ E+ +L I + D G Y C A +
Sbjct: 542 ----ECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTE 597
Query: 392 YQIIYANAELRVLASAP 408
A A L VL + P
Sbjct: 598 LDQDLAKAYLTVLGNCP 614
Score = 79.3 bits (194), Expect = 2e-14
Identities = 82/295 (27%), Positives = 119/295 (40%), Gaps = 43/295 (14%)
Query: 333 DNLLWECKASGKPNPWYTWLKNGERLN----PEERIQIENGTLIITMLNVSD----SGVY 384
DN+L EC+A G P P + W +N N P ++ +GTL+I + G Y
Sbjct: 57 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 116
Query: 385 QCAAENKYQIIYANAELRVLASAPDFSKSPVKKKS-----FVQVGGDIVIGCKPN-AFPR 438
QC A NK+ +N +R+ SKSP+ K VQ G + + C P P
Sbjct: 117 QCFARNKFGTALSN-RIRL-----QVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPS 170
Query: 439 AAISWKRGT-ETLRQSKRIFLLEDGSLKIYNITRSDAGS-YTCIATNQFG---------T 487
I W + E + Q KR+ +G L N+ D + Y+C A F T
Sbjct: 171 PVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFT 230
Query: 488 AKNTGSLIVKERTVITVPP----SKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVID 543
K + V ERT + P S V G ++L C S P+ ++ W+ G D
Sbjct: 231 LKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIA--WYKKGG--D 286
Query: 544 LKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPP 598
L A FE L I N+ SG+Y C + S+ + V+ P
Sbjct: 287 LPSDKAKFENFNKA----LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAP 337
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 194 bits (492), Expect = 5e-49
Identities = 206/819 (25%), Positives = 321/819 (39%), Gaps = 82/819 (10%)
Query: 26 PIFTQEPHDVIFPLDLSKSE-VILNCAANGYPSPHYRWKQNG----TDIDFTMSYHYRLD 80
P + P D+I +SK E LNC A G P+P W + G TD D S+ L
Sbjct: 29 PRIVEHPSDLI----VSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLP 84
Query: 81 GGSL----AINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVRE 136
GSL ++ + D G+Y C+A N LG +S A L+ A + D + S V V
Sbjct: 85 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAV 144
Query: 137 GQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTC 196
G+ V+ C PP + + +W + +PL +D ++ G L I SD G Y C
Sbjct: 145 GEPAVMECQPPRGHPEPTISWKKDGSPL---DDKDERITIRGGKLMITYTRKSDAGKYVC 201
Query: 197 FITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPV 256
TN +R + +++R V+ P + D S + +C A G+PV
Sbjct: 202 VGTNMVGERESEVAELTVLERPS----------FVKRPSNLAVTVDDSAEFKCEARGDPV 251
Query: 257 PDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYA 316
P + WR+ DG LP + L+I D G Y C+A N+ G+ A L
Sbjct: 252 PTVRWRKDDGE-LPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQE 310
Query: 317 PPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGER--------LNPEERIQI-E 367
PP + K ++ +++ + ++C+A+G P P W + G + R + +
Sbjct: 311 PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ 370
Query: 368 NGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVL-----ASAPDFSKSPVKKKSFVQ 422
G L IT + SD G Y C N I A L V P + PV + V
Sbjct: 371 TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT--VA 428
Query: 423 VGGDIVIGCKPNAFPRAAISWKR-GTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIA 481
V G V+ C P I W++ G Q RI LE+G L+I D G YTCIA
Sbjct: 429 VDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIA 488
Query: 482 TNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVW--FFNG 539
+ G A + + V+E V PP D + S +V+ V W N
Sbjct: 489 STPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNS 548
Query: 540 DVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSG-KYLCTVQTTLESLSAVADIIVRGPP 598
+ F G S + N++ S K L L + A + P
Sbjct: 549 GATPTSYIIEAFSHASGSS-WQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPS 607
Query: 599 GPPEDVQVEDISSTTSQLSWRAGPD--NNSPIQIF--TIQTRTPFSVGWQAVATVPEILN 654
+ V+ +D+ T+ + + N+ + + T+ + + V W I
Sbjct: 608 QISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQG 667
Query: 655 GKTY---NATVVGLSPWVEYEFRVVAGNSIGI---------------------GEPSEPS 690
K + G S W+ +E R A NS+ I G SE
Sbjct: 668 YKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSE-I 726
Query: 691 ELLRTKASVPVVAP--VNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTW 748
+ +T P P V + G+ + ++++W+ PE+ QNG Y + +G+ T
Sbjct: 727 KFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWC--LGNET- 783
Query: 749 SKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEG 787
+V+ S F ++P + V+V G G
Sbjct: 784 RYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSG 822
Score = 176 bits (445), Expect = 1e-43
Identities = 191/715 (26%), Positives = 305/715 (42%), Gaps = 79/715 (11%)
Query: 234 PETIQAAKDSSVKLECFA-LGNPVPDISWRRLDGSPLPGK-VKYSKSQAILEIPNFQQED 291
P + A +EC G+P P ISW++ DGSPL K + + L I ++ D
Sbjct: 137 PSDVMVAVGEPAVMECQPPRGHPEPTISWKK-DGSPLDDKDERITIRGGKLMITYTRKSD 195
Query: 292 EGFYECIASNLRG-RNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYT 350
G Y C+ +N+ G R +L P + ++ N +++ D+ ++C+A G P P
Sbjct: 196 AGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVR 255
Query: 351 WLKNGERLNPEERIQI-ENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPD 409
W K+ L P+ R +I ++ TL I + D G Y C AEN A+A L V P
Sbjct: 256 WRKDDGEL-PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV-QEPPH 313
Query: 410 FSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKR-GTETL-------RQSKRIFLLED 461
F P + V +G + C+ P+ AI W+R G++ L + S R + +
Sbjct: 314 FVVKP--RDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQT 371
Query: 462 GSLKIYNITRSDAGSYTCIATNQFGTAKNTGSL----IVKERT--VITVPPSKMDVTVGE 515
G L I N+ RSD G Y C N G+ L ++ +R VI P V V
Sbjct: 372 GDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDG 431
Query: 516 SIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKY 575
+ VL C + P ++ W +G ++ + RI G L IR +L +G+Y
Sbjct: 432 TFVLSCVATGSPVPTIL--WRKDGVLVSTQDS-----RIKQLENGVLQIRYAKLGDTGRY 484
Query: 576 LCTVQTTLESLSAVADIIVRG------PPGP---------PEDVQVEDISSTTSQLSWRA 620
C T + A I V+ PP P P +V D+S T LSW+
Sbjct: 485 TCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQP 544
Query: 621 GPDNNSPIQIFTIQTRTPFS-VGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGN 679
++ + + I+ + S WQ VA N KT + + GL P Y F V A N
Sbjct: 545 NLNSGATPTSYIIEAFSHASGSSWQTVAE-----NVKTETSAIKGLKPNAIYLFLVRAAN 599
Query: 680 SIGIGEPSEPSELLRTKASVPVV--------------APVNIHGGGG-SRSELVITWESI 724
+ GI +PS+ S+ ++T+ +P A +++H S S + + W ++
Sbjct: 600 AYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHW-TV 658
Query: 725 PEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIP----LSPFEVKVGV 780
++ Q + GY I++RP G+ + + V R +N +IP +E+K
Sbjct: 659 DQQSQYIQ--GYKILYRPSGANHGESDWL--VFEVRTPAKNSVVIPDLRKGVNYEIKARP 714
Query: 781 YNNEGEGSLSTVTIVYSGEDEPQLAPRG--TSLQSFSASEMEVSWNAIAWNRNTGRVLGY 838
+ NE +G+ S + + E+ P P+G S + + + VSW + G V Y
Sbjct: 715 FFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEY 774
Query: 839 EVLYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPP 893
+V W ++ V G+ + I L Y V A AG+G S P
Sbjct: 775 KV--WCLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEP 827
Score = 140 bits (353), Expect = 6e-33
Identities = 193/844 (22%), Positives = 326/844 (38%), Gaps = 99/844 (11%)
Query: 224 EYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRR--------LDGSPLPGKVKY 275
++ P+I V P + +K L C A G P P I W + D +
Sbjct: 26 DFPPRI-VEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLP 84
Query: 276 SKSQAILEIPNFQQE--DEGFYECIASNLRGRNLAKGQLIFYA--PPEWEQKIQNTHLSI 331
S S L I + ++ DEG Y C+A N G ++ + A ++ Q + +++
Sbjct: 85 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAV 144
Query: 332 YDNLLWECKAS-GKPNPWYTWLKNGERLNP-EERIQIENGTLIITMLNVSDSGVYQCAAE 389
+ + EC+ G P P +W K+G L+ +ERI I G L+IT SD+G Y C
Sbjct: 145 GEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGT 204
Query: 390 NKYQIIYAN-AELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTE 448
N + AEL VL P F K P V V C+ P + W++
Sbjct: 205 NMVGERESEVAELTVL-ERPSFVKRP--SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDG 261
Query: 449 TLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSK 508
L +S R + +D +LKI +T D GSYTC+A N G A+ + +L V+E V P
Sbjct: 262 ELPKS-RYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRD 320
Query: 509 MDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQ 568
V +G ++ C+ + +P + + + +++ + R GDL I N+Q
Sbjct: 321 QVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQ 380
Query: 569 LHHSGKYLCTVQTTLESLSA-----VADIIVRGPP-----GPPEDVQVED---------I 609
G Y+C S+ V D+I PP GP D
Sbjct: 381 RSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVAT 440
Query: 610 SSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSP-- 667
S + WR + + T +R V + G T T + +P
Sbjct: 441 GSPVPTILWR-----KDGVLVSTQDSR--IKQLENGVLQIRYAKLGDTGRYTCIASTPSG 493
Query: 668 ---WVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESI 724
W Y G + P++P+ L+ + S P V V SR+ + ++W+
Sbjct: 494 EATWSAYIEVQEFGVPVQPPRPTDPN-LIPSAPSKPEVTDV-------SRNTVTLSWQ-- 543
Query: 725 PEELQNGEGFGYII-MFRPVGSTTWS------KEKVSSVESSR------FVYRNESIIPL 771
P YII F ++W K + S+++ + F+ R + +
Sbjct: 544 PNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGI 603
Query: 772 S-PFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQS---FSASEMEVSWNAIA 827
S P ++ V + + L T V + + +L L + S+S +EV W
Sbjct: 604 SDPSQISDPV---KTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTV-- 658
Query: 828 WNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTKN---ITGLKANTIYFASVRAYNT 884
++ + + GY++LY + + KN I L+ Y R +
Sbjct: 659 -DQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFN 717
Query: 885 AGTGPSSPPVNVTTKKSPPSQPPANIAWKLTN---SKLCLNWEHVKTMENESEVLGYKIL 941
G S T + PS PP + + + + ++W+ V YK+
Sbjct: 718 EFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVW 777
Query: 942 YRQNRQSKTHILET-NNTSAELLVPFEED---YLIEIRTVSDGGDGSSSEEIRIPKMSSL 997
N +++ HI +T + ++ +++PF Y +E+ + G G SE P+ L
Sbjct: 778 CLGN-ETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSE----PQFIQL 832
Query: 998 SSRG 1001
+ G
Sbjct: 833 DAHG 836
>gi|4506569 roundabout 1 isoform a [Homo sapiens]
Length = 1651
Score = 194 bits (492), Expect = 5e-49
Identities = 206/819 (25%), Positives = 321/819 (39%), Gaps = 82/819 (10%)
Query: 26 PIFTQEPHDVIFPLDLSKSE-VILNCAANGYPSPHYRWKQNG----TDIDFTMSYHYRLD 80
P + P D+I +SK E LNC A G P+P W + G TD D S+ L
Sbjct: 68 PRIVEHPSDLI----VSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLP 123
Query: 81 GGSL----AINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVRE 136
GSL ++ + D G+Y C+A N LG +S A L+ A + D + S V V
Sbjct: 124 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAV 183
Query: 137 GQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTC 196
G+ V+ C PP + + +W + +PL +D ++ G L I SD G Y C
Sbjct: 184 GEPAVMECQPPRGHPEPTISWKKDGSPL---DDKDERITIRGGKLMITYTRKSDAGKYVC 240
Query: 197 FITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPV 256
TN +R + +++R V+ P + D S + +C A G+PV
Sbjct: 241 VGTNMVGERESEVAELTVLERPS----------FVKRPSNLAVTVDDSAEFKCEARGDPV 290
Query: 257 PDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYA 316
P + WR+ DG LP + L+I D G Y C+A N+ G+ A L
Sbjct: 291 PTVRWRKDDGE-LPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQE 349
Query: 317 PPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGER--------LNPEERIQI-E 367
PP + K ++ +++ + ++C+A+G P P W + G + R + +
Sbjct: 350 PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ 409
Query: 368 NGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVL-----ASAPDFSKSPVKKKSFVQ 422
G L IT + SD G Y C N I A L V P + PV + V
Sbjct: 410 TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT--VA 467
Query: 423 VGGDIVIGCKPNAFPRAAISWKR-GTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIA 481
V G V+ C P I W++ G Q RI LE+G L+I D G YTCIA
Sbjct: 468 VDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIA 527
Query: 482 TNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVW--FFNG 539
+ G A + + V+E V PP D + S +V+ V W N
Sbjct: 528 STPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNS 587
Query: 540 DVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSG-KYLCTVQTTLESLSAVADIIVRGPP 598
+ F G S + N++ S K L L + A + P
Sbjct: 588 GATPTSYIIEAFSHASGSS-WQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPS 646
Query: 599 GPPEDVQVEDISSTTSQLSWRAGPD--NNSPIQIF--TIQTRTPFSVGWQAVATVPEILN 654
+ V+ +D+ T+ + + N+ + + T+ + + V W I
Sbjct: 647 QISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQG 706
Query: 655 GKTY---NATVVGLSPWVEYEFRVVAGNSIGI---------------------GEPSEPS 690
K + G S W+ +E R A NS+ I G SE
Sbjct: 707 YKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSE-I 765
Query: 691 ELLRTKASVPVVAP--VNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTW 748
+ +T P P V + G+ + ++++W+ PE+ QNG Y + +G+ T
Sbjct: 766 KFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWC--LGNET- 822
Query: 749 SKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEG 787
+V+ S F ++P + V+V G G
Sbjct: 823 RYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSG 861
Score = 176 bits (445), Expect = 1e-43
Identities = 191/715 (26%), Positives = 305/715 (42%), Gaps = 79/715 (11%)
Query: 234 PETIQAAKDSSVKLECFA-LGNPVPDISWRRLDGSPLPGK-VKYSKSQAILEIPNFQQED 291
P + A +EC G+P P ISW++ DGSPL K + + L I ++ D
Sbjct: 176 PSDVMVAVGEPAVMECQPPRGHPEPTISWKK-DGSPLDDKDERITIRGGKLMITYTRKSD 234
Query: 292 EGFYECIASNLRG-RNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYT 350
G Y C+ +N+ G R +L P + ++ N +++ D+ ++C+A G P P
Sbjct: 235 AGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVR 294
Query: 351 WLKNGERLNPEERIQI-ENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPD 409
W K+ L P+ R +I ++ TL I + D G Y C AEN A+A L V P
Sbjct: 295 WRKDDGEL-PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV-QEPPH 352
Query: 410 FSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKR-GTETL-------RQSKRIFLLED 461
F P + V +G + C+ P+ AI W+R G++ L + S R + +
Sbjct: 353 FVVKP--RDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQT 410
Query: 462 GSLKIYNITRSDAGSYTCIATNQFGTAKNTGSL----IVKERT--VITVPPSKMDVTVGE 515
G L I N+ RSD G Y C N G+ L ++ +R VI P V V
Sbjct: 411 GDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDG 470
Query: 516 SIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKY 575
+ VL C + P ++ W +G ++ + RI G L IR +L +G+Y
Sbjct: 471 TFVLSCVATGSPVPTIL--WRKDGVLVSTQDS-----RIKQLENGVLQIRYAKLGDTGRY 523
Query: 576 LCTVQTTLESLSAVADIIVRG------PPGP---------PEDVQVEDISSTTSQLSWRA 620
C T + A I V+ PP P P +V D+S T LSW+
Sbjct: 524 TCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQP 583
Query: 621 GPDNNSPIQIFTIQTRTPFS-VGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGN 679
++ + + I+ + S WQ VA N KT + + GL P Y F V A N
Sbjct: 584 NLNSGATPTSYIIEAFSHASGSSWQTVAE-----NVKTETSAIKGLKPNAIYLFLVRAAN 638
Query: 680 SIGIGEPSEPSELLRTKASVPVV--------------APVNIHGGGG-SRSELVITWESI 724
+ GI +PS+ S+ ++T+ +P A +++H S S + + W ++
Sbjct: 639 AYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHW-TV 697
Query: 725 PEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIP----LSPFEVKVGV 780
++ Q + GY I++RP G+ + + V R +N +IP +E+K
Sbjct: 698 DQQSQYIQ--GYKILYRPSGANHGESDWL--VFEVRTPAKNSVVIPDLRKGVNYEIKARP 753
Query: 781 YNNEGEGSLSTVTIVYSGEDEPQLAPRG--TSLQSFSASEMEVSWNAIAWNRNTGRVLGY 838
+ NE +G+ S + + E+ P P+G S + + + VSW + G V Y
Sbjct: 754 FFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEY 813
Query: 839 EVLYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPP 893
+V W ++ V G+ + I L Y V A AG+G S P
Sbjct: 814 KV--WCLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEP 866
Score = 142 bits (359), Expect = 1e-33
Identities = 198/868 (22%), Positives = 332/868 (38%), Gaps = 108/868 (12%)
Query: 209 GPPTPLVQRTDGVMG---------EYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDI 259
G P P D +G ++ P+I V P + +K L C A G P P I
Sbjct: 41 GTPIPTSDNDDNSLGYTGSRLRQEDFPPRI-VEHPSDLIVSKGEPATLNCKAEGRPTPTI 99
Query: 260 SWRR--------LDGSPLPGKVKYSKSQAILEIPNFQQE--DEGFYECIASNLRGRNLAK 309
W + D + S S L I + ++ DEG Y C+A N G ++
Sbjct: 100 EWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSH 159
Query: 310 GQLIFYA--PPEWEQKIQNTHLSIYDNLLWECKAS-GKPNPWYTWLKNGERLNP-EERIQ 365
+ A ++ Q + +++ + + EC+ G P P +W K+G L+ +ERI
Sbjct: 160 NASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERIT 219
Query: 366 IENGTLIITMLNVSDSGVYQCAAENKYQIIYAN-AELRVLASAPDFSKSPVKKKSFVQVG 424
I G L+IT SD+G Y C N + AEL VL P F K P V V
Sbjct: 220 IRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVL-ERPSFVKRP--SNLAVTVD 276
Query: 425 GDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQ 484
C+ P + W++ L +S R + +D +LKI +T D GSYTC+A N
Sbjct: 277 DSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDHTLKIRKVTAGDMGSYTCVAENM 335
Query: 485 FGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDL 544
G A+ + +L V+E V P V +G ++ C+ + +P + + + +++
Sbjct: 336 VGKAEASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFS 395
Query: 545 KKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSA-----VADIIVRGPP- 598
+ R GDL I N+Q G Y+C S+ V D+I PP
Sbjct: 396 YQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPP 455
Query: 599 ----GPPEDVQVED---------ISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQA 645
GP D S + WR + + T +R
Sbjct: 456 VIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWR-----KDGVLVSTQDSR--IKQLENG 508
Query: 646 VATVPEILNGKTYNATVVGLSP-----WVEYEFRVVAGNSIGIGEPSEPSELLRTKASVP 700
V + G T T + +P W Y G + P++P+ L+ + S P
Sbjct: 509 VLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPN-LIPSAPSKP 567
Query: 701 VVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYII-MFRPVGSTTWS------KEKV 753
V V SR+ + ++W+ P YII F ++W K +
Sbjct: 568 EVTDV-------SRNTVTLSWQ--PNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTET 618
Query: 754 SSVESSR------FVYRNESIIPLS-PFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAP 806
S+++ + F+ R + +S P ++ V + + L T V + + +L
Sbjct: 619 SAIKGLKPNAIYLFLVRAANAYGISDPSQISDPV---KTQDVLPTSQGVDHKQVQRELGN 675
Query: 807 RGTSLQS---FSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTT 863
L + S+S +EV W ++ + + GY++LY + +
Sbjct: 676 AVLHLHNPTVLSSSSIEVHWTV---DQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPA 732
Query: 864 KN---ITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTN---S 917
KN I L+ Y R + G S T + PS PP + + +
Sbjct: 733 KNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGT 792
Query: 918 KLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHILET-NNTSAELLVPFEED---YLIE 973
+ ++W+ V YK+ N +++ HI +T + ++ +++PF Y +E
Sbjct: 793 AILVSWQPPPEDTQNGMVQEYKVWCLGN-ETRYHINKTVDGSTFSVVIPFLVPGIRYSVE 851
Query: 974 IRTVSDGGDGSSSEEIRIPKMSSLSSRG 1001
+ + G G SE P+ L + G
Sbjct: 852 VAASTGAGSGVKSE----PQFIQLDAHG 875
>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
Length = 1447
Score = 193 bits (491), Expect = 6e-49
Identities = 217/821 (26%), Positives = 340/821 (41%), Gaps = 101/821 (12%)
Query: 234 PETIQAAKDSSVKLECFALGNP-VPDISWRRLDGSPLP---GKVKYSKSQAILEIPNF-- 287
P + +V L+C A + VP I W++ DG L + K S L I N
Sbjct: 46 PSDAVTMRGGNVLLDCSAESDRGVPVIKWKK-DGIHLALGMDERKQQLSNGSLLIQNILH 104
Query: 288 ---QQEDEGFYECIAS-NLRGRNLAKGQLIFYAPP-EWEQKIQNTHLSIYDNLLWECKAS 342
+ DEG Y+C AS G +++ + A P + + ++ + D +L +C+
Sbjct: 105 SRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVI 164
Query: 343 GKPNPWYTWLKNGERLNP----EERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYAN 398
G+P P W KN + L P + + +G L I+ L D G+Y+C+A N N
Sbjct: 165 GEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGN 224
Query: 399 -AELRVLASAPDFSKSPV---KKKSFVQVGG-DIVIGCKPNAFPRAAISWKRGTETLR-Q 452
AE+R+L S P + + + V + G D V+ C + +P + +W RG E ++ +
Sbjct: 225 EAEVRIL-SDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLR 283
Query: 453 SKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVP-----PS 507
SK+ LL +L I N+T D+G YTC+ T KN E TV+ P PS
Sbjct: 284 SKKYSLLGGSNLLISNVTDDDSGMYTCVVTY-----KNENISASAELTVLVPPWFLNHPS 338
Query: 508 KMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNI 567
+ I C VS P V W NGDV+ +F+ +GG + L I +
Sbjct: 339 NLYAYESMDIEFECTVSGKPVPTVN--WMKNGDVVIPSD---YFQIVGGSN---LRILGV 390
Query: 568 QLHHSGKYLCTVQTTLESLSAVADIIVRGP--------PGPPEDVQVEDISSTTSQLSWR 619
G Y C + + A +IV P P P DV +SS +LSWR
Sbjct: 391 VKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRLSWR 450
Query: 620 AGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGN 679
+ IQ FT+ +A+ T + TV L P Y FRVVA N
Sbjct: 451 PPAEAKGNIQTFTVFFSREGDNRERALNTT----QPGSLQLTVGNLKPEAMYTFRVVAYN 506
Query: 680 SIGIGEPSEPSELLRTKASVPVVAPV-NIHGGGGSRSELVITWESIPEELQNGEGFGYII 738
G GE S+P + + T+ + V PV N+ S + ++ITWE P NG GY +
Sbjct: 507 EWGPGESSQPIK-VATQPELQVPGPVENLQAVSTSPTSILITWE--PPAYANGPVQGYRL 563
Query: 739 MFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSG 798
T S K ++E Y+ E + + + ++ YN G G + V +
Sbjct: 564 F-----CTEVSTGKEQNIEVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTL 618
Query: 799 EDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIR-V 857
D P P+ SL+ ++ ++VSW G + GY++ + K + G++ +
Sbjct: 619 SDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRH----RKTTRRGEMETL 674
Query: 858 SGNVTTKNITGLKANTIYFASVRAYNTAGTGPSS------PPVNVTTKKSPPSQPPANIA 911
N TGL+ + Y V A GTGP S P N + P QP +
Sbjct: 675 EPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHV 734
Query: 912 WKLTNSKLCLNWEHVKTMENESEVLGYKILY----------RQNRQSKTHILETNNTSAE 961
TN C+ + V GY I Y R + + + + +E +S+
Sbjct: 735 RPQTN---CIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSH 791
Query: 962 LLVPFEEDYLIEIRTVSDGGDGSSSEEIRIPKMSSLSSRGI 1002
Y+I ++ ++ G+G +P S ++R I
Sbjct: 792 --------YVISLKAFNNAGEG-------VPLYESATTRSI 817
Score = 171 bits (432), Expect = 4e-42
Identities = 235/987 (23%), Positives = 392/987 (39%), Gaps = 116/987 (11%)
Query: 28 FTQEPHDVIFPLDLSKSEVILNCAANGYPS-PHYRWKQNGTDIDFTMSYH-YRLDGGSLA 85
F EP D + + V+L+C+A P +WK++G + M +L GSL
Sbjct: 42 FLSEPSDAV---TMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLL 98
Query: 86 I----NSPHTDQDIGMYQCLAT-NLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGV 140
I +S H D G+YQC A+ G+I+SR AK+ A F ++T S V+ G V
Sbjct: 99 IQNILHSRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTES-VTAFMGDTV 157
Query: 141 VLLCG----PPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTC 196
+L C P P + W N L + R V +G L I++++P D+G Y C
Sbjct: 158 LLKCEVIGEPMP-----TIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRC 212
Query: 197 FITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPV 256
N + R+ ++ G + ++ P + A + LEC G P
Sbjct: 213 SARNPASSRTGNEAEVRILSDP----GLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPP 268
Query: 257 PDISWRRLDGSPLPGKVKYSK-SQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFY 315
P +W R + KYS + L I N +D G Y C+ + A +L
Sbjct: 269 PSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVL 328
Query: 316 APPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQIENGT-LIIT 374
PP + N + ++ +EC SGKP P W+KNG+ + P + QI G+ L I
Sbjct: 329 VPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRIL 388
Query: 375 MLNVSDSGVYQCAAENKYQIIYANAEL----------RVLASAPDFSKSPVKKKSFVQVG 424
+ SD G YQC AEN+ +A+L VL SAP + FV++
Sbjct: 389 GVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRLS 448
Query: 425 GDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLK--IYNITRSDAGSYTCIAT 482
K N + G + + + + GSL+ + N+ ++ +A
Sbjct: 449 WRPPAEAKGNIQTFTVFFSREGD---NRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAY 505
Query: 483 NQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDP---------SIEVVF 533
N++G +++ + V + + VP ++ + ++ +P +
Sbjct: 506 NEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEPPAYANGPVQGYRLFC 565
Query: 534 VWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADII 593
G +++ ++ G + + +R + + G + T T+ +LS V
Sbjct: 566 TEVSTGKEQNIEVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDV---- 621
Query: 594 VRGPPGPPEDVQVEDISSTTSQLSWRAGPD--NNSPIQIFTIQTRTPFSVGWQAVATVPE 651
P PP++V +E ++S + ++SW P N I + I+ R G E
Sbjct: 622 ---PSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEM------E 672
Query: 652 ILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPS-----EPSELLRTKASVPVVAPVN 706
L GL +Y F+V A G G PS E E ++ VP P +
Sbjct: 673 TLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVP-DQPSS 731
Query: 707 IHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNE 766
+H + ++++W P N GYII + VGS + V+S + Y E
Sbjct: 732 LHVRPQTNC-IIMSW--TPPLNPNIVVRGYIIGY-GVGS---PYAETVRVDSKQRYYSIE 784
Query: 767 SIIPLSPFEVKVGVYNNEGEG-----SLSTVTIV--------YSGEDE----------PQ 803
+ S + + + +NN GEG S +T +I Y D+ P
Sbjct: 785 RLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPDLSTPM 844
Query: 804 LAPRGTSLQSFSASEMEVSW--NAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNV 861
L P G + + + VSW N++ N+ T V Y V + T S +
Sbjct: 845 LPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWRT-----SFSASAKYKSED 899
Query: 862 TTK---NITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSK 918
TT TGLK NT+Y SV + S + TT ++ P+ P ++ K
Sbjct: 900 TTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGK 959
Query: 919 ---LCLNWEHVKTMENESEVLGYKILY 942
+ ++W+ +E ++ Y + Y
Sbjct: 960 PRAVIVSWQ--PPLEANGKITAYILFY 984
Score = 127 bits (319), Expect = 5e-29
Identities = 211/938 (22%), Positives = 357/938 (38%), Gaps = 116/938 (12%)
Query: 46 VILNCAANGYPSPHYRWKQNGTDIDFTM--SYHYRLDGGSLAINSPHTDQDIGMYQCLAT 103
V+L C G P P W++N D+ S L G+L I+ DIG+Y+C A
Sbjct: 157 VLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPG-DIGIYRCSAR 215
Query: 104 NLLGTILSRKAKLQFA-----YIEDFETKTRSTVSVREGQGVVLLCG----PPPHFGDLS 154
N + +A+++ + + + + S V EG+ VL C PPP S
Sbjct: 216 NPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPP-----S 270
Query: 155 YAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPL 214
+ W + +Q ++++ NL I+ V D G YTC +T K S T L
Sbjct: 271 FTWLRGEE--VIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVL 328
Query: 215 VQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVK 274
V P + P + A + ++ EC G PVP ++W + +P
Sbjct: 329 V-----------PPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYF 377
Query: 275 YSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAP--------PEWEQKIQN 326
+ L I + DEGFY+C+A N G QLI P P + +
Sbjct: 378 QIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVP 437
Query: 327 THLSI-YDNLLWECKASGKPN-PWYTWLKNGERLNPEERIQI-ENGTLIITMLNVSDSGV 383
+S + L W A K N +T + E N E + + G+L +T+ N+ +
Sbjct: 438 VLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAM 497
Query: 384 Y--QCAAENKYQIIYANAELRVLASAPDFS-KSPVKKKSFVQVGG-DIVIGCKPNAFPRA 439
Y + A N++ ++ ++V A+ P+ PV+ V I+I +P A+
Sbjct: 498 YTFRVVAYNEWGPGESSQPIKV-ATQPELQVPGPVENLQAVSTSPTSILITWEPPAYANG 556
Query: 440 AISWKR--GTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSL-IV 496
+ R TE ++ ++ S K+ + + S +A N++G +T + +V
Sbjct: 557 PVQGYRLFCTEVSTGKEQNIEVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITVV 616
Query: 497 KERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGG 556
V + PP + + V S + +VS P F G I +K E
Sbjct: 617 TLSDVPSAPPQNVSLEVVNSRSI--KVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETL 674
Query: 557 ESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPG-------PPEDVQVEDI 609
E +L L +Y + Q + +++ GPP P D+ +
Sbjct: 675 EP-NNLWYLFTGLEKGSQY--SFQVSAMTVNGT------GPPSNWYTAETPENDLDESQV 725
Query: 610 SSTTSQLSWRAGPDNNSPIQIFT------IQTR---TPFSVGWQAVATVPEILNGKTYNA 660
S L R P N I +T I R + VG TV ++ K
Sbjct: 726 PDQPSSLHVR--PQTNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVR--VDSKQRYY 781
Query: 661 TVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRT----------------------KAS 698
++ L Y + A N+ G G P S R+ S
Sbjct: 782 SIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPDLS 841
Query: 699 VPVVAPVNIHGGGGSRSELVITW--ESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSV 756
P++ PV + + + ++W S+P+ + E Y + +R S + K S
Sbjct: 842 TPMLPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWRTSFSAS---AKYKSE 898
Query: 757 ESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSA 816
+++ Y + P + +E V V N + S + E P AP+ ++ +
Sbjct: 899 DTTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREG 958
Query: 817 SEMEVSWNAIAWN---RNTGRVLGYEVLYWTDDSKESMIGKIR--VSGNVTTKNITGLKA 871
V ++W G++ Y +L++T D + I +SG+ T I L
Sbjct: 959 KPRAV---IVSWQPPLEANGKITAY-ILFYTLDKNIPIDDWIMETISGDRLTHQIMDLNL 1014
Query: 872 NTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPAN 909
+T+Y+ ++A N+ G GP S P+ T K AN
Sbjct: 1015 DTMYYFRIQARNSKGVGPLSDPILFRTLKVEHPDKMAN 1052
Score = 31.6 bits (70), Expect = 4.0
Identities = 33/136 (24%), Positives = 53/136 (38%), Gaps = 14/136 (10%)
Query: 585 SLSAVADIIVRGPPGPPEDVQV--EDISSTTSQLSWRAGPDNNSPIQ----IFTIQTRTP 638
S++A A P P+D+ V + +SW+ + N I +T+ P
Sbjct: 932 SMTAHATTYEAAPTSAPKDLTVITREGKPRAVIVSWQPPLEANGKITAYILFYTLDKNIP 991
Query: 639 FSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKAS 698
W + E ++G ++ L+ Y FR+ A NS G+G S+P K
Sbjct: 992 ID-DW-----IMETISGDRLTHQIMDLNLDTMYYFRIQARNSKGVGPLSDPILFRTLKVE 1045
Query: 699 VP--VVAPVNIHGGGG 712
P + HG GG
Sbjct: 1046 HPDKMANDQGRHGDGG 1061
>gi|157311649 neogenin homolog 1 [Homo sapiens]
Length = 1461
Score = 193 bits (490), Expect = 8e-49
Identities = 192/744 (25%), Positives = 328/744 (44%), Gaps = 62/744 (8%)
Query: 234 PETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAI----LEIPNF-- 287
P + + SSV L C A P P I W++ DG+ L V + Q + L I N
Sbjct: 59 PVDTLSVRGSSVILNCSAYSEPSPKIEWKK-DGTFL-NLVSDDRRQLLPDGSLFISNVVH 116
Query: 288 ---QQEDEGFYECIAS-NLRGRNLAK-GQLIFYAPPEWEQKIQNTHLSIYDNLLWECKAS 342
+ DEG+Y+C+A+ G +++ +LI P + + + + + +N + C+ +
Sbjct: 117 SKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNCEVN 176
Query: 343 GKPNPWYTWLKNGERLNPEER-IQIENGTLIITMLNVSDSGVYQCAAENKYQIIYAN-AE 400
P+ W +N + L ++R I++ +G L+I+ D G+Y+C E+ Y++ E
Sbjct: 177 ADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNATEGDGGLYRCVVESGGPPKYSDEVE 236
Query: 401 LRVLASAPDFSKSPVKKKSFVQV---GGDIVIGCKPNAFPRAAISWKRGTETL--RQSKR 455
L+VL S K+ V G D+V+ C + P I W + E L S+R
Sbjct: 237 LKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSER 296
Query: 456 IFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGE 515
+ LL GSL+I ++T DAG+Y CIA N T + L V+ + P+ +
Sbjct: 297 LVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESM 356
Query: 516 SIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKY 575
IV C+V+ P+ V W NGD++ + + +I E +L + + G Y
Sbjct: 357 DIVFECEVTGKPTPTV--KWVKNGDMVI----PSDYFKIVKEH--NLQVLGLVKSDEGFY 408
Query: 576 LCTVQTTLESLSAVADIIV-------RGP-PGPPEDVQVEDISSTTSQLSWR--AGPDNN 625
C + + + A A +I+ GP P P DV +S+ +L+WR A +
Sbjct: 409 QCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHG 468
Query: 626 SPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGE 685
+ T+ A V + T+ L P Y FRV+A N G GE
Sbjct: 469 DNLTYSVFYTKEGI-----ARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGE 523
Query: 686 PSEPSEL-LRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVG 744
S P + + + +P AP N+ S + + +TWE+ NGE Y + + G
Sbjct: 524 SSAPLRVETQPEVQLPGPAP-NLRAYAASPTSITVTWET--PVSGNGEIQNYKLYYMEKG 580
Query: 745 STTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQL 804
+ +K V+ S Y + + + +V YN G G + V + D P
Sbjct: 581 T-----DKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSA 635
Query: 805 APRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTK 864
AP+ SL+ ++ + + W A G++ GY++ Y S++S + + VSG ++
Sbjct: 636 APQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRY-RKASRKSDVTETLVSGTQLSQ 694
Query: 865 NITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQP-----PANIAWKLTNSKL 919
I GL T Y V A GTGP++ ++ T +S + P+++ + + +
Sbjct: 695 LIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSI 754
Query: 920 CLNWEHVKTMENESEVL-GYKILY 942
++W EN++ V+ GY I Y
Sbjct: 755 VVSW---TPPENQNIVVRGYAIGY 775
Score = 189 bits (480), Expect = 1e-47
Identities = 260/1066 (24%), Positives = 429/1066 (40%), Gaps = 161/1066 (15%)
Query: 28 FTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRL--DGG--- 82
F EP D L + S VILNC+A PSP WK++GT ++ +L DG
Sbjct: 55 FLVEPVDT---LSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFI 111
Query: 83 SLAINSPHTDQDIGMYQCLAT-NLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVV 141
S ++S H D G YQC+AT LGTI+SR AKL A + F ++ + SV G +
Sbjct: 112 SNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPS-SVYAGNNAI 170
Query: 142 LLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNK 201
L C W N PL + + R + +G L I+ D G Y C + +
Sbjct: 171 LNCEVNADLVPF-VRWEQNRQPLLLDD---RVIKLPSGMLVISNATEGDGGLYRCVVESG 226
Query: 202 EAQRSVQGPPTPLVQRTDGVMGEYEPKIEV-------RFPETIQAAKDSSVKLECFALGN 254
GPP + +D V + P EV + P + V L C A G
Sbjct: 227 -------GPP----KYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGL 275
Query: 255 PVPDISWRR----LDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKG 310
P P I W + LD V + LEI + ++D G Y CIA N A+
Sbjct: 276 PTPTIKWMKNEEALDTESSERLVLLAGGS--LEISDVTEDDAGTYFCIADNGNETIEAQA 333
Query: 311 QLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQI-ENG 369
+L A PE+ ++ N + ++++EC+ +GKP P W+KNG+ + P + +I +
Sbjct: 334 ELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEH 393
Query: 370 TLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVI 429
L + L SD G YQC AEN A A+L +L AP + P+ D+V
Sbjct: 394 NLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAP-ATTGPLP-----SAPRDVVA 447
Query: 430 GCKPNAFPRAAISWKRGTETLRQSK---RIFLLEDG---------------SLKIYNITR 471
F + ++W+ +F ++G + I N+
Sbjct: 448 SLVSTRFIK--LTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMP 505
Query: 472 SDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEV 531
+ + +A N+ G+ +++ L V+ + + +P G + L + SI V
Sbjct: 506 ATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLP--------GPAPNLRAYAASPTSITV 557
Query: 532 VFVWFFNGD-------VIDLKKGV---------AHFERIGG-ESVGDLMIRNIQLHHSGK 574
+ +G+ + ++KG +H I G + + R + + G
Sbjct: 558 TWETPVSGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGP 617
Query: 575 YLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWR--AGPDNNSPIQIFT 632
+ T + +LS V P P+++ +E +S + + W+ A N I +
Sbjct: 618 GVSTPDVAVRTLSDV-------PSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYK 670
Query: 633 IQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSE---- 688
I+ R + +++G + + GL EY FRV A G G ++
Sbjct: 671 IRYRK----ASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSA 726
Query: 689 ---PSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGS 745
S+L T+ VP V P ++H S +V++W P E QN GY I + +GS
Sbjct: 727 ETFESDLDETR--VPEV-PSSLHVRPLVTS-IVVSW--TPPENQNIVVRGYAIGY-GIGS 779
Query: 746 TTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEG---SLSTVTIVYSGEDE- 801
+ V+ + Y E++ P S + + + +NN GEG S VT ++ E
Sbjct: 780 ---PHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEV 836
Query: 802 ----------------PQLAPRGTSLQSFSASEMEVSW--NAIAWNRNTGRVLGYEVLYW 843
P + P G S + ++W N++ ++ Y V +
Sbjct: 837 DLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWK 896
Query: 844 TDDSKESMIGKIRVSGNVTTKN--ITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKS 901
T+ + + N TT + +TGLK NT+Y SV + S + TT +
Sbjct: 897 TNIPANTKY----KNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFEL 952
Query: 902 PPSQPPANIAWKLTNSK---LCLNWEHVKTMENESEVLGYKILYRQNRQSKTH------I 952
P+ PP ++ K + +NW+ E ++ GY I Y + ++ H +
Sbjct: 953 VPTSPPKDVTVVSKEGKPKTIIVNWQ--PPSEANGKITGYIIYYSTDVNAEIHDWVIEPV 1010
Query: 953 LETNNTSAELLVPFEEDYLIEIRTVSDGGDGSSSE--EIRIPKMSS 996
+ T + + Y +I+ + G G SE + R PK S
Sbjct: 1011 VGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKADS 1056
Score = 33.5 bits (75), Expect = 1.1
Identities = 33/124 (26%), Positives = 50/124 (40%), Gaps = 5/124 (4%)
Query: 597 PPGPPEDVQV--EDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILN 654
P PP+DV V ++ T ++W+ + N I + I T + P + N
Sbjct: 954 PTSPPKDVTVVSKEGKPKTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGN 1013
Query: 655 GKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVN-IHGGGGS 713
T+ + L Y F++ A NS G+G SE + KA P + G GG
Sbjct: 1014 RLTHQIQELTLD--TPYYFKIQARNSKGMGPMSEAVQFRTPKADSSDKMPNDQASGSGGK 1071
Query: 714 RSEL 717
S L
Sbjct: 1072 GSRL 1075
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 191 bits (485), Expect = 3e-48
Identities = 160/582 (27%), Positives = 251/582 (43%), Gaps = 54/582 (9%)
Query: 26 PIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLA 85
P+ +P ++ L+ + ++L C A G PSP W++ G +++ + H L G L
Sbjct: 3988 PVIQPQPSELHVILN---NPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQ 4044
Query: 86 INSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCG 145
I S +D G Y C+A N GT L K KL + V + + + L C
Sbjct: 4045 I-SRAVREDAGTYMCVAQNPAGTALG-KIKLNVQVPPVISPHLKEYV-IAVDKPITLSCE 4101
Query: 146 ----PPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNK 201
PPP D+++ D V+ +R +S +G+L IA V+P D G+YTC N
Sbjct: 4102 ADGLPPP---DITW---HKDGRAIVESIRQRVLS--SGSLQIAFVQPGDAGHYTCMAANV 4153
Query: 202 EAQRSVQGPPT----PLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVP 257
S T P ++ T+G E +S L C A G P P
Sbjct: 4154 AGSSSTSTKLTVHVPPRIRSTEGHYTVNE---------------NSQAILPCVADGIPTP 4198
Query: 258 DISWRRLDGSPLPGKV-KYSKS---QAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLI 313
I+W++ D L + KY+ + ILE N ED GFY C+A+N G + L
Sbjct: 4199 AINWKK-DNVLLANLLGKYTAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLT 4255
Query: 314 FYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQIENGTLII 373
+ P + + + L+ + L CKA+G P P TW N + + L+I
Sbjct: 4256 VHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVI 4315
Query: 374 TMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKP 433
++ DSG Y C AEN + A + V P K +GG+ ++ C+
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYV--KEPPVFKGDYPSNWIEPLGGNAILNCEV 4373
Query: 434 NAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGS 493
P I W R + S RI L +GSL IY DAG YTC+ATN+ G + + S
Sbjct: 4374 KGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMS 4433
Query: 494 LIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFER 553
L ++ +IT+ P + + G I+L CQ + +P + W G ++ +R
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEP--QPTITWSRQG------HSISWDDR 4485
Query: 554 IGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVR 595
+ S L I + Q + ++ C + + S+ +IV+
Sbjct: 4486 VNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527
Score = 174 bits (440), Expect = 5e-43
Identities = 147/562 (26%), Positives = 235/562 (41%), Gaps = 40/562 (7%)
Query: 45 EVILNCAANGYPSPHYRWKQNG--TDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLA 102
+ L C A G P P W++NG ++D + + L GSL I SP D D Y+C
Sbjct: 3820 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVD-DTATYECTV 3878
Query: 103 TNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDN 162
TN G R L + + + V+ F + WT N
Sbjct: 3879 TNGAGDD-KRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIH--WTKNGI 3935
Query: 163 PLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNK--EAQRSVQGPPTPLVQRTDG 220
L + D R +S +G + I + + G YTC N A R V
Sbjct: 3936 RLLPRGDGYRILS--SGAIEILATQLNHAGRYTCVARNAAGSAHRHV------------- 3980
Query: 221 VMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPL--PGKVKYSKS 278
+ +EP + P + ++ + L C A G P P I+W++ +G + G+
Sbjct: 3981 TLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQK-EGINVNTSGRNHAVLP 4039
Query: 279 QAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWE 338
L+I +ED G Y C+A N G L K +L PP ++ +++ +
Sbjct: 4040 SGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLS 4099
Query: 339 CKASGKPNPWYTWLKNGERLNPEERIQI-ENGTLIITMLNVSDSGVYQCAAENKYQIIYA 397
C+A G P P TW K+G + R ++ +G+L I + D+G Y C A N
Sbjct: 4100 CEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSST 4159
Query: 398 NAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIF 457
+ +L V P +S + V ++ C + P AI+WK+ L +
Sbjct: 4160 STKLTV--HVPPRIRS-TEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKY 4216
Query: 458 LLED-GSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGES 516
E G L + N+ D+G YTC+A N G +T SL V T P + + GE
Sbjct: 4217 TAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQ 4276
Query: 517 IVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYL 576
+ L C+ + P ++ W FN ++I AHF+ + G S +L+I + SG Y+
Sbjct: 4277 LRLSCKATGIPLPKLT--WTFNNNIIP-----AHFDSVNGHS--ELVIERVSKEDSGTYV 4327
Query: 577 CTVQTTLESLSAVADIIVRGPP 598
CT + ++ + A+ + V+ PP
Sbjct: 4328 CTAENSVGFVKAIGFVYVKEPP 4349
Score = 167 bits (423), Expect = 5e-41
Identities = 149/554 (26%), Positives = 227/554 (40%), Gaps = 57/554 (10%)
Query: 41 LSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQC 100
L+KS V L C A G P+P W+++G + + + L+ G L I S H D G Y C
Sbjct: 3726 LNKSTV-LECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHV-TDTGRYLC 3783
Query: 101 LATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCG----PPPHFGDLSYA 156
+ATN GT R+ LQ ++ + ++V L C P P S
Sbjct: 3784 MATNAAGTD-RRRIDLQ-VHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKP-----SIN 3836
Query: 157 WTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITN------KEAQRSVQGP 210
W N + L V ++ + +G+L I D Y C +TN + +VQ P
Sbjct: 3837 WRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVP 3896
Query: 211 PTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLP 270
P+ + TD ++ ++ P + + C A G P P I W + LP
Sbjct: 3897 PSIADEPTDFLVTKHAPAV-----------------ITCTASGVPFPSIHWTKNGIRLLP 3939
Query: 271 GKVKYS-KSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHL 329
Y S +EI Q G Y C+A N G L + PP + + H+
Sbjct: 3940 RGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHV 3999
Query: 330 SIYDNLLWECKASGKPNPWYTWLKNGERLNPEER--IQIENGTLIITMLNVSDSGVYQCA 387
+ + +L C+A+G P+P+ TW K G +N R + +G L I+ D+G Y C
Sbjct: 4000 ILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCV 4059
Query: 388 AENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGT 447
A+N +L V P SP K+ + V I + C+ + P I+W +
Sbjct: 4060 AQNPAGTALGKIKLNV--QVPPVI-SPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDG 4116
Query: 448 ETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPS 507
+ +S R +L GSL+I + DAG YTC+A N G++ + L V I
Sbjct: 4117 RAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG 4176
Query: 508 KMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGG----ESVGDLM 563
V +LPC P+ I+ KK + G E G+L+
Sbjct: 4177 HYTVNENSQAILPCVADGIPT-----------PAINWKKDNVLLANLLGKYTAEPYGELI 4225
Query: 564 IRNIQLHHSGKYLC 577
+ N+ L SG Y C
Sbjct: 4226 LENVVLEDSGFYTC 4239
Score = 159 bits (402), Expect = 1e-38
Identities = 152/578 (26%), Positives = 235/578 (40%), Gaps = 51/578 (8%)
Query: 39 LDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTD-QDIGM 97
+ L + + + C A G P P W +NG + +S H RL I D+ +
Sbjct: 3353 MTLVDTSINIECRATGTPPPQINWLKNG--LPLPLSSHIRLLAAGQVIRIVRAQVSDVAV 3410
Query: 98 YQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLC----GPPPHFGDL 153
Y C+A+N G FA + ++V +G + C P P
Sbjct: 3411 YTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAP----- 3465
Query: 154 SYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRS------V 207
S AW + PL + D VS L + K E D G YTC +N+ + S V
Sbjct: 3466 SMAWLRDGQPLGL--DAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKV 3523
Query: 208 QGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGS 267
PP + G E E I ++ ++L C A G P P ++W + DG
Sbjct: 3524 LEPP--------HINGSEE-------HEEISVIVNNPLELTCIASGIPAPKMTWMK-DGR 3567
Query: 268 PLP--GKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQ 325
PLP +V+ +L I Q ED G Y C+AS+ G + + + + PP +
Sbjct: 3568 PLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDE 3627
Query: 326 NTHLSIYDN--LLWECKASGKPNPWYTWLKNGERLNPEERIQIENG--TLIITMLNVSDS 381
+++ N + ECK+ P P TWL+NGERL R++I +G L I ++ D+
Sbjct: 3628 PRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDT 3687
Query: 382 GVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAI 441
Y C A N L V P+ P + + + V+ C P I
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVNV-PPNIKGGP--QSLVILLNKSTVLECIAEGVPTPRI 3744
Query: 442 SWKR-GTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERT 500
+W++ G R +LE+G L I + +D G Y C+ATN GT + L V
Sbjct: 3745 TWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPP 3804
Query: 501 VITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVG 560
I P+ M V V L C+ + P + W NG ++++ + + + S G
Sbjct: 3805 SIAPGPTNMTVIVNVQTTLACEATGIPKPSI--NWRKNGHLLNVDQNQNSYRLL---SSG 3859
Query: 561 DLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPP 598
L+I + + + Y CTV D+ V+ PP
Sbjct: 3860 SLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3897
Score = 157 bits (397), Expect = 5e-38
Identities = 164/622 (26%), Positives = 248/622 (39%), Gaps = 62/622 (9%)
Query: 24 SRPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGT----DIDFTMSYHYRL 79
S P+F QEP DV + S V L C GYP P +W++ F++S +L
Sbjct: 791 SPPVFIQEPADVSMEIG---SNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQL 847
Query: 80 DGGSLAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQG 139
G+L I + D G Y C A N G I S + + S +V EGQ
Sbjct: 848 RTGALFILNLWAS-DKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQ 906
Query: 140 VVLLC-----GPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNY 194
+ L C P P W N L N + G+L+I +V+ D G Y
Sbjct: 907 LTLPCTLLAGNPIPE-----RRWIKNSAMLL---QNPYITVRSDGSLHIERVQLQDGGEY 958
Query: 195 TCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGN 254
TC +N + +T V+ P I+ + + + V L C A GN
Sbjct: 959 TCVASNVAGTNN----------KTTSVVVHVLPTIQ-HGQQILSTIEGIPVTLPCKASGN 1007
Query: 255 PVPDISWRRLDGSPLPGKVKYSK-SQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLI 313
P P + W + K+S + L + + E+ G Y C A+N G K QL
Sbjct: 1008 PKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLT 1067
Query: 314 FYAPPEW--------EQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNP--EER 363
Y P + K + + + C+ P P TW K + ++P
Sbjct: 1068 VYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRH 1127
Query: 364 IQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQV 423
+ +G++ IT SDSG+Y C A N + +L V P + P K VQV
Sbjct: 1128 TFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVP-PKIQRGPKHLK--VQV 1184
Query: 424 GGDIVIGCKPNAFPRAAISWKRGTET-LRQSKRIFLLEDGSLKIYNITRSDAGSYTCIAT 482
G + I C P I+W +G T L + DG+L I T SDAG YTC+AT
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVAT 1244
Query: 483 NQFGTAKNTGSLIVKERTVIT--VPPSK---MDVTVGESIVLPCQVSHDPSIEVVFVWFF 537
N GT + +L V+E + PP + + I PC P + W
Sbjct: 1245 NIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIK--WLH 1302
Query: 538 NG-DVIDLKKGVAHFERIGGESVGDLM-IRNIQLHHSGKYLCTVQTTLESLSAVADIIVR 595
NG ++ + G++ E G L+ I ++ + +G+Y+C + ++ V
Sbjct: 1303 NGRELTGREPGISILED------GTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVH 1356
Query: 596 GPPGPPEDVQVEDISSTTSQLS 617
PP + QV ++S +QL+
Sbjct: 1357 VPPVIKDKEQVTNVSVLLNQLT 1378
Score = 152 bits (384), Expect = 2e-36
Identities = 161/635 (25%), Positives = 256/635 (40%), Gaps = 67/635 (10%)
Query: 41 LSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQC 100
+ K+ V L C A+G P P W ++G + + S L GG + T +D G Y C
Sbjct: 2399 VEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAGQYTC 2457
Query: 101 LATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLC----GPPPHFGDLSYA 156
+ N G T V V+E Q V L C P P
Sbjct: 2458 VVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEI-----T 2512
Query: 157 WTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQ 216
W + PL QED + L I V+ G YTC ++ +S V
Sbjct: 2513 WHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVS 2570
Query: 217 RTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPG--KVK 274
T +G PE + +S L C A P I+W + DG+PL ++
Sbjct: 2571 PTIAGVGSDGN------PEDVTVILNSPTSLVCEAYSYPPATITWFK-DGTPLESNRNIR 2623
Query: 275 YSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPP------EWEQKI--QN 326
L+I N Q+++ G Y C+A+N G + ++ Y PP W + +
Sbjct: 2624 ILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKE 2683
Query: 327 THLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQI-ENG-TLIITMLNVSDSGVY 384
+ + + L EC+A P+ +W K+G+ L ++ + I NG TL I +SD+G Y
Sbjct: 2684 VKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRY 2743
Query: 385 QCAAEN-----------KYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKP 433
C A N Q+ + +L + + D ++ K V + I + C+
Sbjct: 2744 TCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKD--VIINNPISLYCET 2801
Query: 434 NAFPRAAISWKRGTETLRQSKRIFLLEDGS-LKIYNITRSDAGSYTCIATNQFGTAKNTG 492
NA P ++W + L S ++ +L G L+I DAG YTC+A N+ G
Sbjct: 2802 NAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQY 2861
Query: 493 SLIVKERTVI----TVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGV 548
+ V +I + P ++ V V +S ++ C S P+ W +G + L+
Sbjct: 2862 DVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPR--NSWQKDGQPL-LEDD- 2917
Query: 549 AHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPP---GPPED-- 603
H + + + L I N Q+ G+Y+C + T S ++ V PP GP +
Sbjct: 2918 -HHKFLSNGRI--LQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENL 2974
Query: 604 -VQVEDISSTTSQLSWRAGPD-----NNSPIQIFT 632
V V + S T ++S PD N PI++ T
Sbjct: 2975 TVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNT 3009
Score = 150 bits (380), Expect = 5e-36
Identities = 151/603 (25%), Positives = 236/603 (39%), Gaps = 53/603 (8%)
Query: 46 VILNCAANGYPSPHYRWKQNGTDIDFTMSYHYR-LDGGSLAINSPHTDQDIGMYQCLATN 104
V L C A G P P W +N I+ + S R L GGS + D G Y C+A+N
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 105 LLGTILSRKAKLQFAYIEDFET----KTRSTVSVREGQGVVLLCG----PPPHFGDLSYA 156
+ G + K F I+ + + S VSV G+ V L+C P P
Sbjct: 3229 MEG----KAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLI-----Q 3279
Query: 157 WTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQ 216
W + P+ E R VS L I SD G YTC TN + V
Sbjct: 3280 WLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVT 3339
Query: 217 RTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLP--GKVK 274
T + G + E + D+S+ +EC A G P P I+W + +G PLP ++
Sbjct: 3340 PT--IRGNKDEA------EKLMTLVDTSINIECRATGTPPPQINWLK-NGLPLPLSSHIR 3390
Query: 275 YSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIY-- 332
+ ++ I Q D Y C+ASN G + L +APP + + +++
Sbjct: 3391 LLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKG 3450
Query: 333 DNLLWECKASGKPNPWYTWLKNGERLNPEERIQIENGTLIITML--NVSDSGVYQCAAEN 390
+ C G P P WL++G+ L + + + +++ +L DSG Y C A N
Sbjct: 3451 SSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASN 3510
Query: 391 KYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETL 450
+ + + L+VL P + S ++ V V + + C + P ++W + L
Sbjct: 3511 EAGEVSKHFILKVL-EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPL 3569
Query: 451 RQSKRIFLLEDGS-LKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKM 509
Q+ ++ L G L+I D G YTC+A++ G + V I
Sbjct: 3570 PQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPR 3629
Query: 510 DVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQL 569
D+TV + + + D V W NG+ + V GG L I N L
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILS--GGRY---LQINNADL 3684
Query: 570 HHSGKYLCTVQTTLESLSAVADIIVRGPP---GPPEDVQVEDISST----------TSQL 616
+ Y C + + V PP G P+ + + ST T ++
Sbjct: 3685 GDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRI 3744
Query: 617 SWR 619
+WR
Sbjct: 3745 TWR 3747
Score = 149 bits (375), Expect = 2e-35
Identities = 157/601 (26%), Positives = 237/601 (39%), Gaps = 74/601 (12%)
Query: 30 QEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSP 89
+ P++ F ++ + C A G P P +W NG ++ L+ G+L + +
Sbjct: 1268 EPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIAS 1327
Query: 90 HTDQDIGMYQCLATNLLGTILSRKAKLQF---AYIEDFETKTRSTVSVREGQGVVLLC-- 144
T D G Y C+A N GT RK L+ I+D E T VSV Q L C
Sbjct: 1328 VTPYDNGEYICVAVNEAGT-TERKYNLKVHVPPVIKDKEQVT--NVSVLLNQLTNLFCEV 1384
Query: 145 -GPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITN--- 200
G P W + DN + V E + L + + P D G Y+C N
Sbjct: 1385 EGTPSPI----IMW-YKDN-VQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438
Query: 201 ---KEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVP 257
K V PPT I FP + + V LEC G P P
Sbjct: 1439 TSQKYFNIDVLVPPT---------------IIGTNFPNEVSVVLNRDVALECQVKGTPFP 1483
Query: 258 DISWRRLDGSPL---PGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIF 314
DI W + DG PL V+ +L + N ++ D+G Y+C SN G+ +L
Sbjct: 1484 DIHWFK-DGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
Query: 315 YAPPEWEQKIQNTHLSIYDNLL--WECKASGKPNPWYTWLKNGER-LNPEERIQIENGT- 370
Y PP + T +S+ N L EC+ G P P TW K+G+ ++ + + I+ G
Sbjct: 1543 YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY 1602
Query: 371 LIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSK----SPVKKKSFVQVGGD 426
L I VSDS Y C N A V P + +P+ K+ V +
Sbjct: 1603 LHIPRAQVSDSATYTCHVANVAGT--AEKSFHVDVYVPPMIEGNLATPLNKQ--VVIAHS 1658
Query: 427 IVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDG-SLKIYNITRSDAGSYTCIATNQF 485
+ + CK P ++W + ++ + I + G L+I + D G Y C+AT+
Sbjct: 1659 LTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVA 1718
Query: 486 GTAKNTGSLIVKERTVITVPP--------SKMDVTVGESIVLPCQVSHDPSIEVVFVWFF 537
G + +K + VPP S V V + L C V+ P + +W
Sbjct: 1719 GEKE------IKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTI--MWLK 1770
Query: 538 NGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGP 597
+G +ID + G + G L+I Q+ ++G Y C T ++ V P
Sbjct: 1771 DGQLIDERDGFKIL--LNGRK---LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVP 1825
Query: 598 P 598
P
Sbjct: 1826 P 1826
Score = 149 bits (375), Expect = 2e-35
Identities = 146/584 (25%), Positives = 239/584 (40%), Gaps = 62/584 (10%)
Query: 46 VILNCAANGYPSPHYRWKQNGTDIDFTMSYHYR-LDGGSLAINSPHTDQDIGMYQCLATN 104
+ L C ++G P P+ WK+ G+ + R L GG S D +Y C+A+N
Sbjct: 2214 ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASN 2273
Query: 105 LLGTILSRKAKLQFAYIEDFETKTRS---TVSVREGQGVVLLCG----PPPHFGDLSYAW 157
+ GT ++ LQ YI T + S + V G+ + L C PPP + W
Sbjct: 2274 VAGTA-KKEYNLQ-VYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP-----TVTW 2326
Query: 158 TFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCF------ITNKEAQRSVQGPP 211
+ +PL + + E L + + SD G Y C +T+K+ SV PP
Sbjct: 2327 MKDGHPLIKAKGVE--ILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP 2384
Query: 212 TPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSP--L 269
+ ++G + R PE I + +SV L C A G P+P I+W + DG P L
Sbjct: 2385 S--------IIGNH------RSPENISVVEKNSVSLTCEASGIPLPSITWFK-DGWPVSL 2429
Query: 270 PGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPE--WEQKIQNT 327
V+ +L + ED G Y C+ N G L PP E +++
Sbjct: 2430 SNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDV 2489
Query: 328 HLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQIENG--TLIITMLNVSDSGVYQ 385
+ ++ C+ +G P P TW K+G+ L +E I +G L IT + V +G Y
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYT 2549
Query: 386 CAAENKYQIIYANAELRVLAS--APDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISW 443
C A + + L V S + V + + C+ ++P A I+W
Sbjct: 2550 CLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITW 2609
Query: 444 KRGTETLRQSKRIFLLEDG-SLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVI 502
+ L ++ I +L G +L+I N +AG Y+C+ATN+ G + V +I
Sbjct: 2610 FKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPII 2669
Query: 503 T--------VPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERI 554
+ P ++ + V ++ L C+ PS + W+ +G + K H
Sbjct: 2670 NKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPL---KSDDHVNIA 2724
Query: 555 GGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPP 598
L I+ Q+ +G+Y C D+ ++ PP
Sbjct: 2725 ANGHT--LQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPP 2766
Score = 149 bits (375), Expect = 2e-35
Identities = 153/564 (27%), Positives = 225/564 (39%), Gaps = 45/564 (7%)
Query: 48 LNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLG 107
L C A+G P+P W ++G + T L GG + S +D G Y CLA++ G
Sbjct: 3548 LTCIASGIPAPKMTWMKDGRPLPQTDQVQ-TLGGGEVLRISTAQVEDTGRYTCLASSPAG 3606
Query: 108 TILSRKAKLQFAYIED--FETKTRSTVSVREGQGVVLLCG----PPPHFGDLSYAWTFND 161
K L ++ T ++V + V L C PPP W N
Sbjct: 3607 D--DDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVI-----TWLRNG 3659
Query: 162 NPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGV 221
L Q R + L I + D NYTC +N + G T T V
Sbjct: 3660 ERL--QATPRVRILSGGRYLQINNADLGDTANYTCVASN------IAGKTTREFILTVNV 3711
Query: 222 MGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGK-VKYS-KSQ 279
P I+ P+++ + S LEC A G P P I+WR+ DG+ L G +YS
Sbjct: 3712 ----PPNIKGG-PQSLVILLNKSTVLECIAEGVPTPRITWRK-DGAVLAGNHARYSILEN 3765
Query: 280 AILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWEC 339
L I + D G Y C+A+N G + + L + PP N + + C
Sbjct: 3766 GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLAC 3825
Query: 340 KASGKPNPWYTWLKNGERLNPEERIQ----IENGTLIITMLNVSDSGVYQCAAENKYQII 395
+A+G P P W KNG LN ++ + +G+L+I +V D+ Y+C N
Sbjct: 3826 EATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3885
Query: 396 YANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISW-KRGTETLRQSK 454
+L V P + P V VI C + P +I W K G L +
Sbjct: 3886 KRTVDLTVQVP-PSIADEPTD--FLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGD 3942
Query: 455 RIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVG 514
+L G+++I + AG YTC+A N G+A +L V E VI PS++ V +
Sbjct: 3943 GYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILN 4002
Query: 515 ESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGK 574
I+LPC+ + PS W G ++ G H G L I +G
Sbjct: 4003 NPILLPCEATGTPS--PFITWQKEGINVN-TSGRNH----AVLPSGGLQISRAVREDAGT 4055
Query: 575 YLCTVQTTLESLSAVADIIVRGPP 598
Y+C Q + + V+ PP
Sbjct: 4056 YMCVAQNPAGTALGKIKLNVQVPP 4079
Score = 147 bits (371), Expect = 5e-35
Identities = 161/597 (26%), Positives = 243/597 (40%), Gaps = 64/597 (10%)
Query: 46 VILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNL 105
V L C ANG P+P W ++ ++ G + + +D G Y C+ATN
Sbjct: 1844 VALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNA 1903
Query: 106 LGTILSRKAKLQF---AYIEDFETKTRSTVSVREGQGVVLLC----GPPPHFGDLSYAWT 158
G + +L +ED TV V V L C P P W
Sbjct: 1904 AGET-QQHIQLHVHEPPSLEDAGKMLNETVLV--SNPVQLECKAAGNPVPVI-----TW- 1954
Query: 159 FNDNPLYVQEDNRRFVSQETGNLY-IAKVEPSDVGNYTCFITNK----EAQRSVQGPPTP 213
+ DN L + F+++ G + I + SD G Y C N E S+Q P
Sbjct: 1955 YKDNRLLSGSTSMTFLNR--GQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAP 2012
Query: 214 LVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPG-- 271
+ ++ + + ++ V+LEC A G P P ++W + DGSP+
Sbjct: 2013 SISGSNNM---------------VAVVVNNPVRLECEARGIPAPSLTWLK-DGSPVSSFS 2056
Query: 272 -KVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLS 330
++ IL + + Q D G Y C+A N G L Y PP + QN +
Sbjct: 2057 NGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVL 2116
Query: 331 IYDNLLWECKASGKPNPWYTWLKNGERL--NPEERIQIENGTLIITMLNVSDSGVYQCAA 388
I + C++ P P TWLK+G L P I L I V D+G Y C A
Sbjct: 2117 ISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEA 2176
Query: 389 ENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISW-KRGT 447
N N + + P+ S + V G I + C+ + P + W K+G+
Sbjct: 2177 TNVAGKTEKNYNVNIWV-PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGS 2235
Query: 448 ETLRQSK-RIFLLEDG-SLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVIT-- 503
L S R+ +L G L+I +SDA Y+C+A+N GTAK +L V R IT
Sbjct: 2236 PVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNS 2295
Query: 504 -VPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDL 562
P+++ VT G+SI L C+V P V W +G + KGV + G L
Sbjct: 2296 GSHPTEIIVTRGKSISLECEVQGIPPPTV--TWMKDGHPLIKAKGVEILDE--GHI---L 2348
Query: 563 MIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPG------PPEDVQVEDISSTT 613
++NI + +G+Y+C D+ V PP PE++ V + +S +
Sbjct: 2349 QLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVS 2405
Score = 145 bits (367), Expect = 1e-34
Identities = 155/594 (26%), Positives = 238/594 (40%), Gaps = 50/594 (8%)
Query: 46 VILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNL 105
V L C A+G P P W + G I + + GSL + SP ++ G Y C ATN
Sbjct: 998 VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEES-GEYVCTATNT 1056
Query: 106 LGTILSRKAKLQ-------FAYIEDFETKTRSTVSVREGQGVVLLCG----PPPHFGDLS 154
G RK +L F +SV G+ V L C PPP
Sbjct: 1057 AG-YAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPII---- 1111
Query: 155 YAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPL 214
T+ + + R +G++ I + SD G Y C TN + G T
Sbjct: 1112 ---TWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATN------IAGNVTQA 1162
Query: 215 VQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPL-PGKV 273
V+ V PKI+ R P+ ++ V + C A G P+P I+W + + L G+
Sbjct: 1163 VKLNVHV----PPKIQ-RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEH 1217
Query: 274 KYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYD 333
S L I D G Y C+A+N+ G + + L PP E + + +
Sbjct: 1218 HVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQE 1277
Query: 334 NLL-----WECKASGKPNPWYTWLKNGERLNPEER--IQIENGTL-IITMLNVSDSGVYQ 385
+ + C A G P P WL NG L E +E+GTL +I + D+G Y
Sbjct: 1278 RVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYI 1337
Query: 386 CAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKR 445
C A N+ L+V K V S V + + C+ P I W +
Sbjct: 1338 CVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVS-VLLNQLTNLFCEVEGTPSPIIMWYK 1396
Query: 446 GTETLRQSKRIFLLEDGS-LKIYNITRSDAGSYTCIATNQFGTAKNTGSL--IVKERTVI 502
+ +S I + +G LK++ T DAG Y+C A N GT++ ++ +V +
Sbjct: 1397 DNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIG 1456
Query: 503 TVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDL 562
T P+++ V + + L CQV P ++ WF +G + L G + E + V L
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIH--WFKDGKPLFL--GDPNVELLDRGQV--L 1510
Query: 563 MIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQL 616
++N + + G+Y CTV + + + PP DIS + L
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSL 1564
Score = 145 bits (367), Expect = 1e-34
Identities = 161/636 (25%), Positives = 257/636 (40%), Gaps = 67/636 (10%)
Query: 8 VILLPLINSSAGDGLLSRPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGT 67
V + P I DG P DV L+ S L C A YP W ++GT
Sbjct: 2567 VFVSPTIAGVGSDG---------NPEDVTVILN---SPTSLVCEAYSYPPATITWFKDGT 2614
Query: 68 DIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTILSR-KAKLQFAYIEDFET 126
++ + G +L I + D + G Y C+ATN G ++ + K+ YI
Sbjct: 2615 PLESNRNIRILPGGRTLQILNAQED-NAGRYSCVATNEAGEMIKHYEVKV---YIPPIIN 2670
Query: 127 K--------TRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQET 178
K + V ++ + L C S +W + PL + D+ ++
Sbjct: 2671 KGDLWGPGLSPKEVKIKVNNTLTLECEAYA-IPSASLSWYKDGQPL--KSDDHVNIAANG 2727
Query: 179 GNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEV-RFPETI 237
L I + + SD G YTC +N + + V + + E ++ R E
Sbjct: 2728 HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAK 2787
Query: 238 QAAKDSSVKLECFALGNPVPDISWRRLDGSPLPG--KVKYSKSQAILEIPNFQQEDEGFY 295
++ + L C P P ++W + DG PL KV +L+IP + ED G Y
Sbjct: 2788 DVIINNPISLYCETNAAPPPTLTWYK-DGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRY 2846
Query: 296 ECIASNLRGRNLAKGQLIFYAPPEWE----QKIQNTHLSIYDNLLWECKASGKPNPWYTW 351
C+A N G + + + PP + + + + + L EC +SG P P +W
Sbjct: 2847 TCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSW 2906
Query: 352 LKNGERLNPEERIQIENGTLIITMLN--VSDSGVYQCAAENKYQIIYANAELRVLASAPD 409
K+G+ L ++ + + I+ +LN ++D G Y C AEN L V P
Sbjct: 2907 QKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNV--HVPP 2964
Query: 410 FSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDG-SLKIYN 468
P + V V I + C+ + FP +SW + + ++ + ++ G +L+I
Sbjct: 2965 SVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIR 3024
Query: 469 ITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMD----------VTVGESIV 518
SD G YTCIA NQ G +K SL + VPPS D V G S+
Sbjct: 3025 AKVSDGGEYTCIAINQAGESKKKFSL------TVYVPPSIKDHDSESLSVVNVREGTSVS 3078
Query: 519 LPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCT 578
L C+ + P V W+ NG +I H E + + L I+ ++ +G+Y+C
Sbjct: 3079 LECESNAVP--PPVITWYKNGRMITES---THVEILADGQM--LHIKKAEVSDTGQYVCR 3131
Query: 579 VQTTLESLSAVADIIVRGPP---GPPEDVQVEDISS 611
+ V PP GP +V VE IS+
Sbjct: 3132 AINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISN 3167
Score = 140 bits (353), Expect = 6e-33
Identities = 155/587 (26%), Positives = 233/587 (39%), Gaps = 53/587 (9%)
Query: 16 SSAGDGLLSRPIFTQEPHDVI-FPLDLSKS---EVILNCAANGYPSPHYRWKQNGTDIDF 71
SSAG G EP VI P +++ + +L C + W++N D+
Sbjct: 503 SSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRL 562
Query: 72 TMSYHYR-LDGGSLAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKT-- 128
R L SL + S + D G Y C+ ++ G+ A F +++ T
Sbjct: 563 AEPARIRTLANLSLELKSVKFN-DAGEYHCMVSSEGGS----SAASVFLTVQEPPKVTVM 617
Query: 129 RSTVSVREGQGVVLLCG----PPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIA 184
S G V ++C P P AWT ND +++ +R ++ + G L+I
Sbjct: 618 PKNQSFTGGSEVSIMCSATGYPKPKI-----AWTVND--MFIVGSHRYRMTSD-GTLFIK 669
Query: 185 KVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSS 244
P D G Y C +N A Q ++ PK+ V E + A D +
Sbjct: 670 NAAPKDAGIYGCLASNS-AGTDKQNSTLRYIEA---------PKLMVVQSELLVALGDIT 719
Query: 245 VKLECFALGNPVPDISWRRLDGSPLPGK-VKYSKSQAILEIPNFQQEDEGFYECIASNLR 303
V +EC G P P + W + D P + +L+I Q D G Y C+A N
Sbjct: 720 V-MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEA 778
Query: 304 GRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTW--LKN----GER 357
GR K L +PP + Q+ + + I N+ C G P P W L N
Sbjct: 779 GRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRP 838
Query: 358 LNPEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLAS-APDFSKSPVK 416
+ Q+ G L I L SD G Y C AEN++ I + + V AP SP
Sbjct: 839 FSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISP-- 896
Query: 417 KKSFVQVGGDIVIGCKPNAF-PRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAG 475
+ V G + + C A P W + + L Q+ I + DGSL I + D G
Sbjct: 897 SVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGG 956
Query: 476 SYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVW 535
YTC+A+N GT T S++V I + G + LPC+ S +P V +W
Sbjct: 957 EYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSV--IW 1014
Query: 536 FFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTT 582
G++I + + G L + + SG+Y+CT T
Sbjct: 1015 SKKGELISTSSA-----KFSAGADGSLYVVSPGGEESGEYVCTATNT 1056
Score = 139 bits (351), Expect = 1e-32
Identities = 153/586 (26%), Positives = 226/586 (38%), Gaps = 66/586 (11%)
Query: 41 LSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQC 100
L+ EV L C P P W + I H L GS+ I T D GMY C
Sbjct: 1092 LAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTS-DSGMYLC 1150
Query: 101 LATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCG----PPPHFGDLSYA 156
+ATN+ G + ++ KL ++ + + V+ GQ V + C P P
Sbjct: 1151 VATNIAGNV-TQAVKLN-VHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVI-----T 1203
Query: 157 WTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITN------KEAQRSVQGP 210
W+ + + V D VS G L I + PSD G YTC TN E VQ P
Sbjct: 1204 WSKGGSTMLV--DGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEP 1261
Query: 211 PTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLP 270
PT + + EP F E + + ++ C A G P P I W +G L
Sbjct: 1262 PT---------VEDLEPPYNTTFQERVA---NQRIEFPCPAKGTPKPTIKWLH-NGRELT 1308
Query: 271 GK---VKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNT 327
G+ + + +L I + D G Y C+A N G K L + PP + K Q T
Sbjct: 1309 GREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVT 1368
Query: 328 HLSIYDNLLWE--CKASGKPNPWYTWLKNGERLNPEERIQIENGTLIITMLNVS--DSGV 383
++S+ N L C+ G P+P W K+ ++ IQ N I+ + + D+G
Sbjct: 1369 NVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGR 1428
Query: 384 YQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISW 443
Y C A N + VL P + + V + D+ + C+ P I W
Sbjct: 1429 YSCKAINIAGTSQKYFNIDVLV-PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHW 1487
Query: 444 -KRGTETLRQSKRIFLLEDGS-LKIYNITRSDAGSYTCIATNQFG-TAKNTGSLIVKERT 500
K G + LL+ G L + N R+D G Y C +N G AK+ +
Sbjct: 1488 FKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDI-------KL 1540
Query: 501 VITVPPS--------KMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFE 552
I +PPS + V + I L C+ P + W+ +G I + +
Sbjct: 1541 TIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAI--TWYKDGQPIMSSSQALYID 1598
Query: 553 RIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPP 598
+ G+ L I Q+ S Y C V + + V PP
Sbjct: 1599 K--GQY---LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPP 1639
Score = 138 bits (347), Expect = 3e-32
Identities = 151/569 (26%), Positives = 222/569 (39%), Gaps = 43/569 (7%)
Query: 47 ILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDG--GSLAINSPHTDQDIGMYQCLATN 104
++ C +G P P +W + D++ S +D G L I D D G Y C+A N
Sbjct: 720 VMECKTSGIPPPQVKWFKG--DLELRPSTFLIIDPLLGLLKIQETQ-DLDAGDYTCVAIN 776
Query: 105 LLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDN-P 163
G K L F + + VS+ G V L C + + + W DN P
Sbjct: 777 EAGRATG-KITLDVGSPPVF-IQEPADVSMEIGSNVTLPCYVQG-YPEPTIKWRRLDNMP 833
Query: 164 LYVQEDNRRFVSQ-ETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVM 222
++ + + +SQ TG L+I + SD G Y C N+ + +Q + T V
Sbjct: 834 IFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGK--IQS------ETTVTVT 885
Query: 223 GEYEPKIEVRFPETIQAAKDSSVKLECFAL-GNPVPDISWRRLDGSPLPGKVKYSKSQAI 281
G P I + P + + L C L GNP+P+ W + L +S
Sbjct: 886 GLVAPLIGIS-PSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS 944
Query: 282 LEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWE--QKIQNTHLSIYDNLLWEC 339
L I Q +D G Y C+ASN+ G N ++ + P + Q+I +T I L C
Sbjct: 945 LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTL--PC 1002
Query: 340 KASGKPNPWYTWLKNGERLNPEER--IQIENGTLIITMLNVSDSGVYQCAAENKYQIIYA 397
KASG P P W K GE ++ +G+L + +SG Y C A N
Sbjct: 1003 KASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKR 1062
Query: 398 NAELRVLASAPDFSKS-------PVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETL 450
+L V F PV+ V G ++ + C+ + P I+W + T+ +
Sbjct: 1063 KVQLTVYVRPRVFGDQRGLSQDKPVEIS--VLAGEEVTLPCEVKSLPPPIITWAKETQLI 1120
Query: 451 RQ-SKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKM 509
S R L GS+KI SD+G Y C+ATN G L V I P +
Sbjct: 1121 SPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHL 1180
Query: 510 DVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQL 569
V VG+ + +PC P V W G + L G H G L I
Sbjct: 1181 KVQVGQRVDIPCNAQGTPL--PVITWSKGGSTM-LVDGEHHV----SNPDGTLSIDQATP 1233
Query: 570 HHSGKYLCTVQTTLESLSAVADIIVRGPP 598
+G Y C + + V+ PP
Sbjct: 1234 SDAGIYTCVATNIAGTDETEITLHVQEPP 1262
Score = 132 bits (331), Expect = 2e-30
Identities = 146/582 (25%), Positives = 223/582 (38%), Gaps = 49/582 (8%)
Query: 29 TQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINS 88
T EP D+ L +V L C ++ P P W +NG + T G L IN+
Sbjct: 3625 TDEPRDITV---LRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINN 3681
Query: 89 PHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLC---- 144
D Y C+A+N+ G +R+ L + + +S V + + VL C
Sbjct: 3682 ADLG-DTANYTCVASNIAGK-TTREFILTVNVPPNIKGGPQSLV-ILLNKSTVLECIAEG 3738
Query: 145 GPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQ 204
P P T+ + + ++ R+ E G L+I +D G Y C TN
Sbjct: 3739 VPTPRI-------TWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGT 3791
Query: 205 RSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRL 264
+R D + + P P + + L C A G P P I+WR+
Sbjct: 3792 DR---------RRID--LQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRK- 3839
Query: 265 DGSPLPGKVKYSK----SQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEW 320
+G L + S L I + +D YEC +N G + L PP
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSI 3899
Query: 321 EQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPE---ERIQIENGTLIITMLN 377
+ + ++ + + C ASG P P W KNG RL P RI + +G + I
Sbjct: 3900 ADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRI-LSSGAIEILATQ 3958
Query: 378 VSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFP 437
++ +G Y C A N + + L V P P + V + I++ C+ P
Sbjct: 3959 LNHAGRYTCVARNAAGSAHRHVTLHV-HEPPVIQPQP--SELHVILNNPILLPCEATGTP 4015
Query: 438 RAAISW-KRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIV 496
I+W K G + +L G L+I R DAG+Y C+A N GTA L V
Sbjct: 4016 SPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Query: 497 KERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGG 556
+ VI+ + + V + I L C+ P ++ W +G + + R
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDI--TWHKDG------RAIVESIRQRV 4127
Query: 557 ESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPP 598
S G L I +Q +G Y C S S + V PP
Sbjct: 4128 LSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 130 bits (328), Expect = 5e-30
Identities = 135/520 (25%), Positives = 212/520 (40%), Gaps = 40/520 (7%)
Query: 91 TDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFET-KTRSTVSVREGQGVVLLCGPPPH 149
T D G Y+C+A + GT +A+ F E + + V+V G+ VL C
Sbjct: 490 TLSDEGFYECIAVSSAGT---GRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIISA 546
Query: 150 FGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQG 209
D + W ND + + E R + +L + V+ +D G Y C ++++ +
Sbjct: 547 V-DYNLTWQRNDRDVRLAEP-ARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASV 604
Query: 210 PPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPL 269
T + PK+ V P+ S V + C A G P P I+W ++ +
Sbjct: 605 FLTV----------QEPPKVTV-MPKNQSFTGGSEVSIMCSATGYPKPKIAW-TVNDMFI 652
Query: 270 PGKVKY-SKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTH 328
G +Y S L I N +D G Y C+ASN G + L + P+
Sbjct: 653 VGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELL 712
Query: 329 LSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQIEN--GTLIITMLNVSDSGVYQC 386
+++ D + ECK SG P P W K L P + I+ G L I D+G Y C
Sbjct: 713 VALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTC 772
Query: 387 AAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRG 446
A N+ L V S P F + P +++G ++ + C +P I W+R
Sbjct: 773 VAINEAGRATGKITLDV-GSPPVFIQEPADVS--MEIGSNVTLPCYVQGYPEPTIKWRRL 829
Query: 447 TETLRQSK-----RIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVK--ER 499
S+ I L G+L I N+ SD G+Y C A NQFG ++ ++ V
Sbjct: 830 DNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVA 889
Query: 500 TVITVPPSKMDVTVGESIVLPCQ-VSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGES 558
+I + PS +V G+ + LPC ++ +P E W N ++ I S
Sbjct: 890 PLIGISPSVANVIEGQQLTLPCTLLAGNPIPE--RRWIKNSAML------LQNPYITVRS 941
Query: 559 VGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPP 598
G L I +QL G+Y C + + ++V P
Sbjct: 942 DGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 129 bits (324), Expect = 1e-29
Identities = 148/595 (24%), Positives = 236/595 (39%), Gaps = 58/595 (9%)
Query: 41 LSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLA--INSPHTDQDIGMY 98
L ++ C ++G P+P W+++G + +H L G + +N+ TD IG Y
Sbjct: 2885 LVNKSALIECLSSGSPAPRNSWQKDGQPL-LEDDHHKFLSNGRILQILNTQITD--IGRY 2941
Query: 99 QCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCG----PPPHFGDLS 154
C+A N G+ + L ++V + L C PPP DLS
Sbjct: 2942 VCVAENTAGSA-KKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPP---DLS 2997
Query: 155 YAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPL 214
W N+ P+ + + T + AKV SD G YTC N+ + + T
Sbjct: 2998 --WLKNEQPIKLNTNTLIVPGGRTLQIIRAKV--SDGGEYTCIAINQAGESKKKFSLTVY 3053
Query: 215 VQRTDGVMGEYEPKIEVRFPETIQAA---KDSSVKLECFALGNPVPDISWRRLDGSPLPG 271
V P I+ E++ + +SV LEC + P P I+W + +G +
Sbjct: 3054 VP----------PSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYK-NGRMITE 3102
Query: 272 K--VKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHL 329
V+ +L I + D G Y C A N+ GR+ L Y PP E + +
Sbjct: 3103 STHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIV 3162
Query: 330 SIYDN-LLWECKASGKPNPWYTWLKNGERLNPEERIQIE----NGTLIITMLNVSDSGVY 384
N + C A+G P P WLKN +R+ + +++ L I SDSG Y
Sbjct: 3163 ETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNY 3222
Query: 385 QCAAEN---KYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAI 441
C A N K Q Y + + P + + + V +G ++ + C N P I
Sbjct: 3223 TCIASNMEGKAQKYYFLS----IQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLI 3278
Query: 442 SWKRGTETLR--QSKRIFLLEDGS-LKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKE 498
W + + + +++RI + +GS L IY SD G YTC+ATN G +L V
Sbjct: 3279 QWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYV 3338
Query: 499 RTVI---TVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIG 555
I K+ V SI + C+ + P ++ W NG + L +H +
Sbjct: 3339 TPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQI--NWLKNGLPLPLS---SHIRLLA 3393
Query: 556 GESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDIS 610
V + I Q+ Y C + ++ V PP + E+I+
Sbjct: 3394 AGQV--IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEIT 3446
Score = 125 bits (314), Expect = 2e-28
Identities = 108/428 (25%), Positives = 170/428 (39%), Gaps = 27/428 (6%)
Query: 180 NLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQA 239
NL IAKV SD G Y C + R EP ++ P +
Sbjct: 483 NLDIAKVTLSDEGFYECIAVSSAG-----------TGRAQTFFDVSEPPPVIQVPNNVTV 531
Query: 240 AKDSSVKLECFALGNPVPDISWRRLDGS---PLPGKVKYSKSQAILEIPNFQQEDEGFYE 296
L C + +++W+R D P +++ + + LE+ + + D G Y
Sbjct: 532 TPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIR-TLANLSLELKSVKFNDAGEYH 590
Query: 297 CIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGE 356
C+ S+ G + A L PP+ +N + + C A+G P P W N
Sbjct: 591 CMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDM 650
Query: 357 RLNPEERIQI-ENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPV 415
+ R ++ +GTL I D+G+Y C A N N+ LR + AP V
Sbjct: 651 FIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI-EAPKL--MVV 707
Query: 416 KKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLED---GSLKIYNITRS 472
+ + V +G V+ CK + P + W +G LR S FL+ D G LKI
Sbjct: 708 QSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPS--TFLIIDPLLGLLKIQETQDL 765
Query: 473 DAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVV 532
DAG YTC+A N+ G A +L V V P+ + + +G ++ LPC V P +
Sbjct: 766 DAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIK 825
Query: 533 FVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADI 592
+ N + V+ ++ G L I N+ G Y+C + + + +
Sbjct: 826 WRRLDNMPIFSRPFSVSSISQL---RTGALFILNLWASDKGTYICEAENQFGKIQSETTV 882
Query: 593 IVRGPPGP 600
V G P
Sbjct: 883 TVTGLVAP 890
Score = 122 bits (305), Expect = 2e-27
Identities = 134/578 (23%), Positives = 217/578 (37%), Gaps = 65/578 (11%)
Query: 48 LNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLG 107
L C G PSP W ++ + + + ++ G + T +D G Y C A N+ G
Sbjct: 1380 LFCEVEGTPSPIIMWYKDNVQVTESSTIQ-TVNNGKILKLFRATPEDAGRYSCKAINIAG 1438
Query: 108 TILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLC---GPPPHFGDLSYAWTFNDNPL 164
T T + VSV + V L C G P F D+ W + PL
Sbjct: 1439 TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTP--FPDIH--WFKDGKPL 1494
Query: 165 YVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGE 224
++ + N + + L++ +D G Y C ++N +++
Sbjct: 1495 FLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAK----------------- 1536
Query: 225 YEPKIEVRFPETIQAAK---------DSSVKLECFALGNPVPDISWRRLDGSPL--PGKV 273
+ K+ + P +I+ +S +KLEC G P+P I+W + DG P+ +
Sbjct: 1537 -DIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYK-DGQPIMSSSQA 1594
Query: 274 KYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQ---NTHLS 330
Y L IP Q D Y C +N+ G + Y PP E + N +
Sbjct: 1595 LYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVV 1654
Query: 331 IYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQIENGTLIITMLNVS--DSGVYQCAA 388
I +L ECKA+G P+P TWLK+G + + I+IE G + +++ D G Y C A
Sbjct: 1655 IAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVA 1714
Query: 389 ENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTE 448
+ E+ VL P V V + + C P I W + +
Sbjct: 1715 TSVAGEKEIKYEVDVLV-PPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQ 1773
Query: 449 TLRQSKRIFLLEDG-SLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPS 507
+ + +L +G L I S+ G Y C+A N G K + + VPP+
Sbjct: 1774 LIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKK------EFEVTVHVPPT 1827
Query: 508 KMDVTVGESIV-------LPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVG 560
+ E +V L C + P+ + W + ++ +G + G
Sbjct: 1828 IKSSGLSERVVVKYKPVALQCIANGIPNPSI--TWLKDDQPVNTAQGNLKIQSSGRV--- 1882
Query: 561 DLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPP 598
L I L +G+Y C + V PP
Sbjct: 1883 -LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 97.4 bits (241), Expect = 6e-20
Identities = 98/351 (27%), Positives = 150/351 (42%), Gaps = 18/351 (5%)
Query: 271 GKVKYSKSQAI--LEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTH 328
G +Y K A L+I DEGFYECIA + G A+ PP Q N
Sbjct: 471 GVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVT 530
Query: 329 LSIYDNLLWECKASGKPNPWYTWLKNGE--RLNPEERIQ-IENGTLIITMLNVSDSGVYQ 385
++ + + C + TW +N RL RI+ + N +L + + +D+G Y
Sbjct: 531 VTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYH 590
Query: 386 CAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKR 445
C ++ A+ L V P + P K +SF G ++ I C +P+ I+W
Sbjct: 591 CMVSSEGGSSAASVFLTV-QEPPKVTVMP-KNQSFTG-GSEVSIMCSATGYPKPKIAWTV 647
Query: 446 GTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVP 505
+ S R + DG+L I N DAG Y C+A+N GT K +L E + V
Sbjct: 648 NDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVV 707
Query: 506 PSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIR 565
S++ V +G+ V+ C+ S P +V +F GD ++L+ I +G L I+
Sbjct: 708 QSELLVALGDITVMECKTSGIPPPQVK---WFKGD-LELRPSTF---LIIDPLLGLLKIQ 760
Query: 566 NIQLHHSGKYLCTVQTTLESLSAVADIIVRGPP---GPPEDVQVEDISSTT 613
Q +G Y C + + V PP P DV +E S+ T
Sbjct: 761 ETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVT 811
Score = 52.8 bits (125), Expect = 2e-06
Identities = 50/194 (25%), Positives = 86/194 (44%), Gaps = 12/194 (6%)
Query: 408 PDFSKSPVKKKS---FVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSL 464
PD K + +K+ ++Q G I C ++ +S+ R TL + + +L
Sbjct: 428 PDAPKVTMPEKTPGYYLQPGQ---IPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNL 484
Query: 465 KIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVS 524
I +T SD G Y CIA + GT + V E + P+ + VT GE VL C +
Sbjct: 485 DIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLII 544
Query: 525 HDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLE 584
+++ W N D +A RI + L +++++ + +G+Y C V +
Sbjct: 545 --SAVDYNLTWQRN----DRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGG 598
Query: 585 SLSAVADIIVRGPP 598
S +A + V+ PP
Sbjct: 599 SSAASVFLTVQEPP 612
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,416,886
Number of Sequences: 37866
Number of extensions: 2026772
Number of successful extensions: 16424
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 257
Number of HSP's successfully gapped in prelim test: 269
Number of HSP's that attempted gapping in prelim test: 6067
Number of HSP's gapped (non-prelim): 4236
length of query: 1028
length of database: 18,247,518
effective HSP length: 112
effective length of query: 916
effective length of database: 14,006,526
effective search space: 12829977816
effective search space used: 12829977816
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.