Search of human proteins with 7657154

Search of human proteins with 7657154

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7657154 hairy/enhancer-of-split related with YRPW motif-like
[Homo sapiens]
         (328 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7657154 hairy/enhancer-of-split related with YRPW motif-like ...   653   0.0  
gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Ho...   217   1e-56
gi|105990528 hairy/enhancer-of-split related with YRPW motif 1 i...   212   4e-55
gi|105990526 hairy/enhancer-of-split related with YRPW motif 1 i...   206   2e-53
gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens]     93   3e-19
gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens]    92   5e-19
gi|5031763 hairy and enhancer of split 1 [Homo sapiens]                90   3e-18
gi|71274142 HES/HEY-like transcription factor [Homo sapiens]           72   5e-13
gi|58219048 hairy and enhancer of split 5 [Homo sapiens]               68   1e-11
gi|13540521 basic helix-loop-helix domain containing, class B, 3...    67   2e-11
gi|145207994 hairy and enhancer of split 7 [Homo sapiens]              66   5e-11
gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens]       60   3e-09
gi|4503299 basic helix-loop-helix family, member e40 [Homo sapiens]    53   3e-07
gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens]     52   7e-07
gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens]    52   9e-07
gi|71852582 aryl hydrocarbon receptor nuclear translocator-like ...    48   1e-05
gi|71852580 aryl hydrocarbon receptor nuclear translocator-like ...    48   1e-05
gi|42716311 aryl hydrocarbon receptor nuclear translocator-like ...    48   1e-05
gi|30795240 aryl hydrocarbon receptor nuclear translocator isofo...    47   2e-05
gi|4502231 aryl hydrocarbon receptor nuclear translocator isofor...    47   2e-05
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             46   5e-05
gi|38201614 transcription factor-like protein 4 isoform alpha [H...    45   7e-05
gi|38201612 transcription factor-like protein 4 isoform beta [Ho...    45   7e-05
gi|24586667 transcription factor-like protein 4 isoform gamma [H...    45   7e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    45   9e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   3e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    44   3e-04
gi|30795242 aryl hydrocarbon receptor nuclear translocator isofo...    43   3e-04
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]               43   3e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni...    42   6e-04

>gi|7657154 hairy/enhancer-of-split related with YRPW motif-like
           [Homo sapiens]
          Length = 328

 Score =  653 bits (1685), Expect = 0.0
 Identities = 328/328 (100%), Positives = 328/328 (100%)

Query: 1   MKRPKEPSGSDGESDGPIDVGQEGQLSQMARPLSTPSSSQMQARKKRRGIIEKRRRDRIN 60
           MKRPKEPSGSDGESDGPIDVGQEGQLSQMARPLSTPSSSQMQARKKRRGIIEKRRRDRIN
Sbjct: 1   MKRPKEPSGSDGESDGPIDVGQEGQLSQMARPLSTPSSSQMQARKKRRGIIEKRRRDRIN 60

Query: 61  SSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAVDFRSIG 120
           SSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAVDFRSIG
Sbjct: 61  SSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAVDFRSIG 120

Query: 121 FRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPAWPWSFF 180
           FRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPAWPWSFF
Sbjct: 121 FRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPAWPWSFF 180

Query: 181 HSCPGLPALSNQLAILGRVPSPVLPGVSSPAYPIPALRTAPLRRATGIILPARRNVLPSR 240
           HSCPGLPALSNQLAILGRVPSPVLPGVSSPAYPIPALRTAPLRRATGIILPARRNVLPSR
Sbjct: 181 HSCPGLPALSNQLAILGRVPSPVLPGVSSPAYPIPALRTAPLRRATGIILPARRNVLPSR 240

Query: 241 GASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGPTGSAAYVAVPTPNS 300
           GASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGPTGSAAYVAVPTPNS
Sbjct: 241 GASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGPTGSAAYVAVPTPNS 300

Query: 301 SSPGPAGRPAGAMLYHSWVSEITEIGAF 328
           SSPGPAGRPAGAMLYHSWVSEITEIGAF
Sbjct: 301 SSPGPAGRPAGAMLYHSWVSEITEIGAF 328


>gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Homo
           sapiens]
          Length = 337

 Score =  217 bits (552), Expect = 1e-56
 Identities = 158/348 (45%), Positives = 195/348 (56%), Gaps = 31/348 (8%)

Query: 1   MKRPKEPSGSDGESDGPIDVGQE----GQLSQMARPLSTPSS-SQMQARKKRRGIIEKRR 55
           MKRP E + S+ + D  IDVG E    GQ +     L++P++ SQ+ ARKKRRGIIEKRR
Sbjct: 1   MKRPCEETTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRR 60

Query: 56  RDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAVD 115
           RDRIN+SLSELRRLVPTAFEKQGS+KLEKAE+LQMTVDHLKML ATGG G+FDA ALA+D
Sbjct: 61  RDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMD 120

Query: 116 FRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTG------P 169
           F SIGFRECLTEV RYL  +EG  S +DP+R+RL+SHL++ A + E +   +       P
Sbjct: 121 FMSIGFRECLTEVARYLSSVEGLDS-SDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHP 179

Query: 170 LAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPGVSSPAYPIPALRTAPLRRA-TGI 228
           L    W  + FH  P      N L      P  +      P     AL TA    A + +
Sbjct: 180 LHPHHWA-AAFHHLPAALLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSAL 238

Query: 229 ILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGPTG 288
            +P+  +V P     ST     L   AT    A ++ AA  +H  P L  +   P  P  
Sbjct: 239 RMPSTGSVAPCVPPLSTSL---LSLSATVHAAAAAATAA--AHSFP-LSFAGAFPMLPPN 292

Query: 289 SAAYVAVPTPNS--------SSPGPAGRPAGAMLYHSWVSEITEIGAF 328
           +AA VA  T  S        SSP           Y  W    TE+GAF
Sbjct: 293 AAAAVAAATAISPPLSVSATSSPQQTSSGTNNKPYRPWG---TEVGAF 337


>gi|105990528 hairy/enhancer-of-split related with YRPW motif 1
           isoform a [Homo sapiens]
          Length = 304

 Score =  212 bits (539), Expect = 4e-55
 Identities = 153/345 (44%), Positives = 195/345 (56%), Gaps = 58/345 (16%)

Query: 1   MKRPK-EPSGSDGESDGPIDVGQE-----GQLSQMARPLSTPSSSQMQARKKRRGIIEKR 54
           MKR   E S SD E D  I+V +E     G LS     +S  +SSQ+ ARK+RRGIIEKR
Sbjct: 1   MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR 60

Query: 55  RRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAV 114
           RRDRIN+SLSELRRLVP+AFEKQGS+KLEKAE+LQMTVDHLKMLH  GG G+FDA ALA+
Sbjct: 61  RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM 120

Query: 115 DFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPA 174
           D+RS+GFRECL EV RYL ++EG  + +DP+R+RL+SHLN+YA++ E +      L    
Sbjct: 121 DYRSLGFRECLAEVARYLSIIEGLDA-SDPLRVRLVSHLNNYASQREAASGAHAGLGHIP 179

Query: 175 WPWSFFHSCPGLPALSNQLAI-------LGRVPSPVLP---GVSSPAYP-IPALRTAPLR 223
           W   F H     P +++ L +        G   SP  P   G    A+P  PALR AP  
Sbjct: 180 WGTVFGHH----PHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALR-APPS 234

Query: 224 RATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTP 283
            + G +LP           S+++ + PL      +   P S    S H   LL  ++ +P
Sbjct: 235 GSLGPVLPV--------VTSASKLSPPLLSSVASLSAFPFSFG--SFH---LLSPNALSP 281

Query: 284 PGPTGSAAYVAVPTPNSSSPGPAGRPAGAMLYHSWVSEITEIGAF 328
             PT +A                G+P     Y  W    TEIGAF
Sbjct: 282 SAPTQAA--------------NLGKP-----YRPWG---TEIGAF 304


>gi|105990526 hairy/enhancer-of-split related with YRPW motif 1
           isoform b [Homo sapiens]
          Length = 308

 Score =  206 bits (524), Expect = 2e-53
 Identities = 153/349 (43%), Positives = 195/349 (55%), Gaps = 62/349 (17%)

Query: 1   MKRPK-EPSGSDGESDGPIDVGQE-----GQLSQMARPLSTPSSSQMQARKKRRGIIEKR 54
           MKR   E S SD E D  I+V +E     G LS     +S  +SSQ+ ARK+RRGIIEKR
Sbjct: 1   MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR 60

Query: 55  RRDRINSSLSELRRLVPTAFEKQ----GSSKLEKAEVLQMTVDHLKMLHATGGTGFFDAR 110
           RRDRIN+SLSELRRLVP+AFEKQ    GS+KLEKAE+LQMTVDHLKMLH  GG G+FDA 
Sbjct: 61  RRDRINNSLSELRRLVPSAFEKQVMEQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAH 120

Query: 111 ALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPL 170
           ALA+D+RS+GFRECL EV RYL ++EG  + +DP+R+RL+SHLN+YA++ E +      L
Sbjct: 121 ALAMDYRSLGFRECLAEVARYLSIIEGLDA-SDPLRVRLVSHLNNYASQREAASGAHAGL 179

Query: 171 AFPAWPWSFFHSCPGLPALSNQLAI-------LGRVPSPVLP---GVSSPAYP-IPALRT 219
               W   F H     P +++ L +        G   SP  P   G    A+P  PALR 
Sbjct: 180 GHIPWGTVFGHH----PHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALR- 234

Query: 220 APLRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSS 279
           AP   + G +LP           S+++ + PL      +   P S    S H   LL  +
Sbjct: 235 APPSGSLGPVLPV--------VTSASKLSPPLLSSVASLSAFPFSFG--SFH---LLSPN 281

Query: 280 SPTPPGPTGSAAYVAVPTPNSSSPGPAGRPAGAMLYHSWVSEITEIGAF 328
           + +P  PT +A                G+P     Y  W    TEIGAF
Sbjct: 282 ALSPSAPTQAA--------------NLGKP-----YRPWG---TEIGAF 308


>gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens]
          Length = 221

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 69/184 (37%), Positives = 95/184 (51%), Gaps = 17/184 (9%)

Query: 39  SQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGS--SKLEKAEVLQMTVDHLK 96
           S  + RK  + ++EKRRR RIN SL++L+ L+  A  K+ S  SKLEKA++L+MTV HL+
Sbjct: 30  SAAEHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLR 89

Query: 97  MLHATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSY 156
            L     T    A    +     GF ECL EV R+L   EG  +    VR RLL HL + 
Sbjct: 90  SLRRVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPA---DVRSRLLGHLAAC 146

Query: 157 AAEMEPSP-----TPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPGVSS-- 209
             ++ PS      +P  P   PA     +   P LP+L     +L     P+LPG++   
Sbjct: 147 LRQLGPSRRPASLSPAAPAEAPA--PEVYAGRPLLPSLGGPFPLLA---PPLLPGLTRAL 201

Query: 210 PAYP 213
           PA P
Sbjct: 202 PAAP 205



 Score = 28.9 bits (63), Expect = 6.6
 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 5/86 (5%)

Query: 224 RATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTP 283
           R  G +    R + PSR  +S   A P E PA   P   + R    S   P    + P  
Sbjct: 138 RLLGHLAACLRQLGPSRRPASLSPAAPAEAPA---PEVYAGRPLLPSLGGPFPLLAPPLL 194

Query: 284 PGPTGSAAYVAVPTPNSSSPGPAGRP 309
           PG T   A  A P      PG   RP
Sbjct: 195 PGLT--RALPAAPRAGPQGPGGPWRP 218


>gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens]
          Length = 247

 Score = 92.4 bits (228), Expect = 5e-19
 Identities = 74/202 (36%), Positives = 103/202 (50%), Gaps = 28/202 (13%)

Query: 21  GQEGQLSQMARPLSTPSSSQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGS- 79
           G+EG+ +Q   P+  P SS        + ++EKRRR RIN SL++L+ L+  A  K+ S 
Sbjct: 49  GREGRGTQ---PVPDPQSS--------KPVMEKRRRARINESLAQLKTLILDALRKESSR 97

Query: 80  -SKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGP 138
            SKLEKA++L+MTV HL+ L     T    A    +     GF ECL EV R+L   EG 
Sbjct: 98  HSKLEKADILEMTVRHLRSLRRVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGV 157

Query: 139 SSRADPVRIRLLSHLNSYAAEMEPSP-----TPTGPLAFPAWPWSFFHSCPGLPALSNQL 193
            +    VR RLL HL +   ++ PS      +P  P   PA     +   P LP+L    
Sbjct: 158 PA---DVRSRLLGHLAACLRQLGPSRRPASLSPAAPAEAPA--PEVYAGRPLLPSLGGPF 212

Query: 194 AILGRVPSPVLPGVSS--PAYP 213
            +L     P+LPG++   PA P
Sbjct: 213 PLLA---PPLLPGLTRALPAAP 231



 Score = 28.9 bits (63), Expect = 6.6
 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 5/86 (5%)

Query: 224 RATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTP 283
           R  G +    R + PSR  +S   A P E PA   P   + R    S   P    + P  
Sbjct: 164 RLLGHLAACLRQLGPSRRPASLSPAAPAEAPA---PEVYAGRPLLPSLGGPFPLLAPPLL 220

Query: 284 PGPTGSAAYVAVPTPNSSSPGPAGRP 309
           PG T   A  A P      PG   RP
Sbjct: 221 PGLT--RALPAAPRAGPQGPGGPWRP 244


>gi|5031763 hairy and enhancer of split 1 [Homo sapiens]
          Length = 280

 Score = 89.7 bits (221), Expect = 3e-18
 Identities = 86/288 (29%), Positives = 122/288 (42%), Gaps = 49/288 (17%)

Query: 17  PIDVGQEGQLSQMARPLSTPSS---------SQMQARKKRRGIIEKRRRDRINSSLSELR 67
           P D+ ++   S +A   +TP+S         +  + RK  + I+EKRRR RIN SLS+L+
Sbjct: 2   PADIMEKNSSSPVA---ATPASVNTTPDKPKTASEHRKSSKPIMEKRRRARINESLSQLK 58

Query: 68  RLVPTAFEKQGS--SKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAVDFRSIGFRECL 125
            L+  A +K  S  SKLEKA++L+MTV HL+ L     T         +     GF EC+
Sbjct: 59  TLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECM 118

Query: 126 TEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPAWPWSFFHSCPG 185
            EV R+L   EG ++    VR RLL HL +         T    + +P  P         
Sbjct: 119 NEVTRFLSTCEGVNTE---VRTRLLGHLAN-------CMTQINAMTYPGQPH-------- 160

Query: 186 LPALSNQLAILGRVPSPVLPGVSSPAYPIPALRTAPLRRATGIILPARRNVLPSRGASST 245
            PAL        + P P  PG   P +  P     PL    G   P         G+ + 
Sbjct: 161 -PAL--------QAPPPPPPGPGGPQH-APFAPPPPLVPIPGGAAPPPGGAPCKLGSQAG 210

Query: 246 RRARPLER-PATPVP------VAPSSRAARSSHIAPLLQSSSPTPPGP 286
             A+        P P      + P+   A S  + P+  S+S T  GP
Sbjct: 211 EAAKVFGGFQVVPAPDGQFAFLIPNGAFAHSGPVIPVYTSNSGTSVGP 258



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 6/42 (14%)

Query: 274 PLLQSSSPTPPGPTG------SAAYVAVPTPNSSSPGPAGRP 309
           P LQ+  P PPGP G      +     VP P  ++P P G P
Sbjct: 161 PALQAPPPPPPGPGGPQHAPFAPPPPLVPIPGGAAPPPGGAP 202


>gi|71274142 HES/HEY-like transcription factor [Homo sapiens]
          Length = 327

 Score = 72.4 bits (176), Expect = 5e-13
 Identities = 71/230 (30%), Positives = 101/230 (43%), Gaps = 58/230 (25%)

Query: 50  IIEKRRRDRINSSLSELRRLVPTAFEKQG------------------------------- 78
           +IEKRRRDRIN  L+EL + VP A  KQG                               
Sbjct: 61  VIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQIRSRVRSLVLSSATVPDQQALGR 120

Query: 79  ----------SSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAVDFRS---IGFRECL 125
                     S KLEKAE+L+MTV +L+ LH+       +   L  +F +    G+ EC+
Sbjct: 121 CEGPFLLLQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEFANYFHYGYHECM 180

Query: 126 TEVIRYLGVLEGPSSRADPVRIRLLSHLNSYA-AEMEPSPTPTGPLAFPAWPW------- 177
             ++ YL  +E   ++ D    R+L+ L S A    EP+  P G L  P + +       
Sbjct: 181 KNLVHYLTTVERMETK-DTKYARILAFLQSKARLGAEPAFPPLGSLPEPDFSYQLHPAGP 239

Query: 178 SFFHSCPGLPALSNQLAILGRVPSPVLPGVS-SPAYPIPALRTAPLRRAT 226
            F    PG  A+  Q +  G  P P  PG + SPA  +P L +AP+  A+
Sbjct: 240 EFAGHSPGEAAVFPQGSGAGPFPWP--PGAARSPA--LPYLPSAPVPLAS 285


>gi|58219048 hairy and enhancer of split 5 [Homo sapiens]
          Length = 166

 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 47/137 (34%), Positives = 75/137 (54%), Gaps = 10/137 (7%)

Query: 39  SQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEK-QGSSKLEKAEVLQMTVDHLKM 97
           S  +  + R+ ++EK RRDRINSS+ +L+ L+   F + Q +SKLEKA++L+M V +LK 
Sbjct: 12  SPKEKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLK- 70

Query: 98  LHATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHL-NSY 156
            H+         ++L  D+ S G+  CL E +++L +       A   +++LL H     
Sbjct: 71  -HSKAFVAAAGPKSLHQDY-SEGYSWCLQEAVQFLTL-----HAASDTQMKLLYHFQRPP 123

Query: 157 AAEMEPSPTPTGPLAFP 173
           AA   P+  P  P A P
Sbjct: 124 AAPAAPAKEPKAPGAAP 140


>gi|13540521 basic helix-loop-helix domain containing, class B, 3
           [Homo sapiens]
          Length = 482

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 44/128 (34%), Positives = 69/128 (53%), Gaps = 14/128 (10%)

Query: 50  IIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDA 109
           +IEK+RRDRIN  +++L+ L+P   +      LEKA VL++T+ HLK L A         
Sbjct: 51  LIEKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLKHLKALTALTEQQHQKI 110

Query: 110 RALAVDFRSI-------------GFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSY 156
            AL    RS+             GF+ C  EV++YL   E  + R +P  ++L++HL++ 
Sbjct: 111 IALQNGERSLKSPIQSDLDAFHSGFQTCAKEVLQYLSRFESWTPR-EPRCVQLINHLHAV 169

Query: 157 AAEMEPSP 164
           A +  P+P
Sbjct: 170 ATQFLPTP 177



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 18/50 (36%), Positives = 24/50 (48%), Gaps = 3/50 (6%)

Query: 250 PLERPATPVPVAPSSRAARSSHIA---PLLQSSSPTPPGPTGSAAYVAVP 296
           PL  P  P P A ++ AA ++  A   P L S    PP   G+AA   +P
Sbjct: 386 PLLYPGIPAPAAAAAAAAAAAAAAAAFPCLSSVLSPPPEKAGAAAATLLP 435


>gi|145207994 hairy and enhancer of split 7 [Homo sapiens]
          Length = 225

 Score = 65.9 bits (159), Expect = 5e-11
 Identities = 59/166 (35%), Positives = 78/166 (46%), Gaps = 16/166 (9%)

Query: 45  KKRRGIIEKRRRDRINSSLSELRRLV--PTAFEKQGSSKLEKAEVLQMTVDHLKMLHATG 102
           K  + ++EKRRRDRIN SL ELR L+   T  +   + KLEKAE+L+  V +L+      
Sbjct: 14  KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVE 73

Query: 103 GTG-----FFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYA 157
             G       DA ALA  + S GFRECL  +  +          +   R +L S L+ Y 
Sbjct: 74  PPGVPRSPVQDAEALASCYLS-GFRECLLRLAAF------AHDASPAARAQLFSALHGYL 126

Query: 158 AEMEPSPTPTGPLAFPAWPWSFFHSCPGL-PALSNQLAILGRVPSP 202
               P P P  P   PA   S   + P L PAL  +  +    PSP
Sbjct: 127 RPKPPRPKPVDPRP-PAPRPSLDPAAPALGPALHQRPPVHQGHPSP 171


>gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens]
          Length = 173

 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 52/144 (36%), Positives = 71/144 (49%), Gaps = 19/144 (13%)

Query: 42  QARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGS--SKLEKAEVLQMTVDHLKMLH 99
           + RK  + ++EKRRR RIN SLS+L+ L+     ++ S  SKLEKA+VL+MTV  L+ L 
Sbjct: 12  ELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQELP 71

Query: 100 ATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRA--DPVRIRLLSHLNSYA 157
           A   + +  A  L  D    G+  C+  + R L     P+ R     V  RLL HL   A
Sbjct: 72  A---SSWPTAAPLPCDSYREGYSACVARLARVL-----PACRVLEPAVSARLLEHLWRRA 123

Query: 158 AEME-------PSPTPTGPLAFPA 174
           A           S  P+ P   PA
Sbjct: 124 ASATLDGGRAGDSSGPSAPAPAPA 147


>gi|4503299 basic helix-loop-helix family, member e40 [Homo sapiens]
          Length = 412

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 47/177 (26%), Positives = 76/177 (42%), Gaps = 30/177 (16%)

Query: 37  SSSQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLK 96
           S    +  K    +IEK+RRDRIN  +++L+ L+P   +      LEKA VL++T+ H+K
Sbjct: 46  SEDSKETYKLPHRLIEKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLKHVK 105

Query: 97  MLHATGGTGFFDARALAV---------------------DFRSIGFRECLTEVIRYLGVL 135
            L     T   D +   +                     +    GF+ C  EV++YL   
Sbjct: 106 AL-----TNLIDQQQQKIIALQSGLQAGELSGRNVETGQEMFCSGFQTCAREVLQYLAKH 160

Query: 136 EGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPAWPWSFFHSCPGLPALSNQ 192
           E   +  D    +L++HL+   +E+    T   P + PA     F   P  PA  ++
Sbjct: 161 E---NTRDLKSSQLVTHLHRVVSELLQGGTSRKP-SDPAPKVMDFKEKPSSPAKGSE 213


>gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens]
          Length = 224

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 37/110 (33%), Positives = 60/110 (54%), Gaps = 6/110 (5%)

Query: 44  RKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGG 103
           RK R+ ++EK+RR RIN SL ELR L+  A   +  +KLE AEVL++TV  ++ +     
Sbjct: 26  RKARKPLVEKKRRARINESLQELRLLLAGA---EVQAKLENAEVLELTVRRVQGVLRGRA 82

Query: 104 TGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHL 153
                 +A A +  + G+ +C+ EV  ++   +   +    V   LL+HL
Sbjct: 83  REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDA---TVAAELLNHL 129


>gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens]
          Length = 222

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 37/110 (33%), Positives = 59/110 (53%), Gaps = 8/110 (7%)

Query: 44  RKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGG 103
           RK R+ ++EK+RR RIN SL ELR L+  A      +KLE AEVL++TV  ++ +     
Sbjct: 26  RKARKPLVEKKRRARINESLQELRLLLAGA-----EAKLENAEVLELTVRRVQGVLRGRA 80

Query: 104 TGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHL 153
                 +A A +  + G+ +C+ EV  ++   +   +    V   LL+HL
Sbjct: 81  REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDA---TVAAELLNHL 127


>gi|71852582 aryl hydrocarbon receptor nuclear translocator-like
          isoform b [Homo sapiens]
          Length = 582

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 27/64 (42%), Positives = 38/64 (59%), Gaps = 2/64 (3%)

Query: 35 TPSSSQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDH 94
          T    +++  ++    IEKRRRD++NS + EL  LVPT      S KL+K  VL+M V H
Sbjct: 21 TEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTC--NAMSRKLDKLTVLRMAVQH 78

Query: 95 LKML 98
          +K L
Sbjct: 79 MKTL 82


>gi|71852580 aryl hydrocarbon receptor nuclear translocator-like
           isoform a [Homo sapiens]
          Length = 625

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 27/64 (42%), Positives = 38/64 (59%), Gaps = 2/64 (3%)

Query: 35  TPSSSQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDH 94
           T    +++  ++    IEKRRRD++NS + EL  LVPT      S KL+K  VL+M V H
Sbjct: 64  TEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTC--NAMSRKLDKLTVLRMAVQH 121

Query: 95  LKML 98
           +K L
Sbjct: 122 MKTL 125


>gi|42716311 aryl hydrocarbon receptor nuclear translocator-like
           isoform a [Homo sapiens]
          Length = 625

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 27/64 (42%), Positives = 38/64 (59%), Gaps = 2/64 (3%)

Query: 35  TPSSSQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDH 94
           T    +++  ++    IEKRRRD++NS + EL  LVPT      S KL+K  VL+M V H
Sbjct: 64  TEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTC--NAMSRKLDKLTVLRMAVQH 121

Query: 95  LKML 98
           +K L
Sbjct: 122 MKTL 125


>gi|30795240 aryl hydrocarbon receptor nuclear translocator isoform
           2 [Homo sapiens]
          Length = 328

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 32/108 (29%), Positives = 51/108 (47%), Gaps = 7/108 (6%)

Query: 2   KRPKEPSGSDGESDGPIDVGQEGQLSQMARPLSTPSSSQMQARKKR-----RGIIEKRRR 56
           +RP      DGE +       + Q+S      +     Q  A K+R        IE+RRR
Sbjct: 43  RRPGLDFDDDGEGNSKFLRCDDDQMSNDKERFARSDDEQSSADKERLARENHSEIERRRR 102

Query: 57  DRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGT 104
           +++ + ++EL  +VPT      + K +K  +L+M V H+K L  TG T
Sbjct: 103 NKMTAYITELSDMVPTC--SALARKPDKLTILRMAVSHMKSLRGTGNT 148


>gi|4502231 aryl hydrocarbon receptor nuclear translocator isoform 1
           [Homo sapiens]
          Length = 789

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 32/108 (29%), Positives = 51/108 (47%), Gaps = 7/108 (6%)

Query: 2   KRPKEPSGSDGESDGPIDVGQEGQLSQMARPLSTPSSSQMQARKKR-----RGIIEKRRR 56
           +RP      DGE +       + Q+S      +     Q  A K+R        IE+RRR
Sbjct: 43  RRPGLDFDDDGEGNSKFLRCDDDQMSNDKERFARSDDEQSSADKERLARENHSEIERRRR 102

Query: 57  DRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGT 104
           +++ + ++EL  +VPT      + K +K  +L+M V H+K L  TG T
Sbjct: 103 NKMTAYITELSDMVPTC--SALARKPDKLTILRMAVSHMKSLRGTGNT 148


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 44/161 (27%), Positives = 63/161 (39%), Gaps = 11/161 (6%)

Query: 155  SYAAEMEPSPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPGVSSPAYPI 214
            S AA + P   PT P A    P         +P      +    VP+P  P   + A P 
Sbjct: 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1087

Query: 215  PALRTAPLRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAP 274
            P   T+P   A  +  P      P+  A++         PA  VP  P   A+ ++ +  
Sbjct: 1088 PEEPTSP---AAAVPTPEE----PTSPAAAVPTPEEPASPAAAVP-TPEEPASPAAAVPT 1139

Query: 275  LLQSSSPTPPGPT---GSAAYVAVPTPNSSSPGPAGRPAGA 312
              + + P P  PT    ++A VAVPTP  S+   A  P  A
Sbjct: 1140 PEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPA 1180



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 47/170 (27%), Positives = 61/170 (35%), Gaps = 14/170 (8%)

Query: 155  SYAAEMEPSPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPGVSSPAYPI 214
            S AA +     PT P A    P         +P      +    VP+P  P   + A P 
Sbjct: 1041 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1100

Query: 215  PALRTAPLRRATGI---ILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSH 271
            P   T+P            PA     P   AS        E PA P P  P+   + S+ 
Sbjct: 1101 PEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAA 1160

Query: 272  IAPLLQSSSPTP----PGPTGSAAYVAV------PT-PNSSSPGPAGRPA 310
            +A      S +P    P P  SA++ AV      PT P +S P PA   A
Sbjct: 1161 VAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 48/185 (25%), Positives = 67/185 (36%), Gaps = 26/185 (14%)

Query: 155  SYAAEMEPSPTPTGPLAFPAWPWS-------FFHSCPGLPALSNQLAILGRVPSPVLPGV 207
            S+AA +     PT P A    P +       F      +P      ++   V +P  P  
Sbjct: 1184 SFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEP-- 1241

Query: 208  SSPAYPIPALRTAPLRRATGIILP------ARRNVLPSRGASSTRRARPLERPATPVPVA 261
            +SPA  +P L   P   A  ++ P      A     P   AS       LE PA+P    
Sbjct: 1242 TSPAAAVPTLEE-PTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAV 1300

Query: 262  PSSRAARSSHIAPLLQSSSPTPPGPTGSAAYVAVPTPNSSSPGPAGRPAGAMLYHSWVSE 321
            P      +  +A +  +S PTP  P   AA V    P      P G P   +  H+    
Sbjct: 1301 P------TPEVAAIPAASVPTPEVPAIPAAAV----PPMEEVSPIGVPFLGVSAHTDSVP 1350

Query: 322  ITEIG 326
            I+E G
Sbjct: 1351 ISEEG 1355



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 47/174 (27%), Positives = 61/174 (35%), Gaps = 12/174 (6%)

Query: 136  EGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAI 195
            E P + A  VR+       S AA +     PT P A    P         +P      + 
Sbjct: 985  EEPDTAA--VRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSP 1042

Query: 196  LGRVPSPVLPGVSSPAYPIPALRTAPLRRATGIILPARRNVLPSRGASSTRRARPLERPA 255
               VP+P  P   + A P P   T+P        +P          A  T         A
Sbjct: 1043 AAAVPTPEEPTSPAAAVPTPEEPTSP-----AAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1097

Query: 256  TPVPVAPSSRAAR--SSHIAPLLQSSSPTPPGPTGSAAYVAVPTPNSSS-PGPA 306
             P P  P+S AA   +        ++ PTP  P   AA  AVPTP   + P PA
Sbjct: 1098 VPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAA--AVPTPEEPAFPAPA 1149



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 24/83 (28%), Positives = 32/83 (38%), Gaps = 8/83 (9%)

Query: 227  GIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGP 286
            G + PA     P    ++  R    E PA+P    P+     S        ++ PTP  P
Sbjct: 973  GPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSP------AAAVPTPEEP 1026

Query: 287  TGSAAYVAVPTPNSSSPGPAGRP 309
            T  AA  AVP P   +   A  P
Sbjct: 1027 TSPAA--AVPPPEEPTSPAAAVP 1047


>gi|38201614 transcription factor-like protein 4 isoform alpha [Homo
           sapiens]
          Length = 214

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 24/64 (37%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 39  SQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQ---GSSKLEKAEVLQMTVDHL 95
           S    R++     E++RRD I     +L+ +VPT  ++    GS KL KA VLQ T+D++
Sbjct: 41  SYKDRRRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYI 100

Query: 96  KMLH 99
           + LH
Sbjct: 101 QFLH 104


>gi|38201612 transcription factor-like protein 4 isoform beta [Homo
           sapiens]
          Length = 244

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 24/64 (37%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 39  SQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQ---GSSKLEKAEVLQMTVDHL 95
           S    R++     E++RRD I     +L+ +VPT  ++    GS KL KA VLQ T+D++
Sbjct: 71  SYKDRRRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYI 130

Query: 96  KMLH 99
           + LH
Sbjct: 131 QFLH 134


>gi|24586667 transcription factor-like protein 4 isoform gamma [Homo
           sapiens]
          Length = 298

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 24/64 (37%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 39  SQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQ---GSSKLEKAEVLQMTVDHL 95
           S    R++     E++RRD I     +L+ +VPT  ++    GS KL KA VLQ T+D++
Sbjct: 125 SYKDRRRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYI 184

Query: 96  KMLH 99
           + LH
Sbjct: 185 QFLH 188


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 52/166 (31%), Positives = 61/166 (36%), Gaps = 31/166 (18%)

Query: 160 MEPS--PTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPS---------PVLPGVS 208
           M PS  P P  P    A P     S P  P +S       RVP          P  P  S
Sbjct: 716 MSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPAS 775

Query: 209 SPAYPI--------PALRTAPLRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPV 260
            P  P+        PAL T PL+      LP+     P +   S   + P+   ATP P 
Sbjct: 776 LPMSPLAKPPPQAPPALATPPLQA-----LPSPPASFPGQAPFSPSASLPMSPLATPPPQ 830

Query: 261 APSSRAARSSHIAPLLQSSSPTPPGPTGSA-AYVAVPTPNSSSPGP 305
           AP   A      APLLQ     P  PT  A      P P++S  GP
Sbjct: 831 APPVLA------APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 870



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 45/150 (30%), Positives = 59/150 (39%), Gaps = 28/150 (18%)

Query: 162 PSPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPGVSSPAYPIPALRTAP 221
           PSP  T P   P  P S     P  P           + SP L G+ SP  P+  L T P
Sbjct: 573 PSPLTTPP---PETPSSIATPPPQAPPA---------LASPPLQGLPSP--PLSPLATPP 618

Query: 222 LRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSP 281
            +    + LP      P +   S   + PL   ATP P AP++ A        LLQ+   
Sbjct: 619 PQAPPXLALP------PLQAPPSPPASPPLSPLATPSPQAPNALAVH------LLQAPFS 666

Query: 282 TPPGPTGSAAY--VAVPTPNSSSPGPAGRP 309
            PP P   A +   A P  + S+  P+  P
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAP 696



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 52/180 (28%), Positives = 69/180 (38%), Gaps = 15/180 (8%)

Query: 132 LGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPAWPWSFFHSCPGLPALSN 191
           L  L  PS +A      L  HL        PSP    P + PA P     + P   A  +
Sbjct: 642 LSPLATPSPQAPNA---LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 698

Query: 192 QLAILGRVPS--PVLPGVSSPAYPIPALRTAPLRRATGIILPARRNVLPSRGASSTRRAR 249
             A   +VP   P  P +S  A P P  +  P   A  + +P      P    S+T   R
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSATPPP--QAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756

Query: 250 -PLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGPTGSAA--YVAVPTPNSSSPGPA 306
            P    A P+ V PS  A+      P+   + P P  P   A     A+P+P +S PG A
Sbjct: 757 VPPLLAAPPLQVPPSPPAS-----LPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQA 811



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 41/139 (29%), Positives = 56/139 (40%), Gaps = 10/139 (7%)

Query: 169 PLAFPAWPWSFFHSCPGLPALSNQLAILGRV---PSPVLPGVSSPAYPIPALRTAPLRRA 225
           PL+ PA         P  PA  +Q    G     P  V P     A  +  L ++PL   
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307

Query: 226 TGIILPARRNVLPSRGASSTRRARPLERP-ATPVPVAPSSRAARSSHIAPLLQSSSPTPP 284
           +     AR    P   A+      P   P ATP+P+AP S +A      P LQ+  P+PP
Sbjct: 308 SPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA-----PPSLQTL-PSPP 361

Query: 285 GPTGSAAYVAVPTPNSSSP 303
               S A  ++ TP   +P
Sbjct: 362 ATPPSQAPPSMTTPPMQAP 380



 Score = 32.0 bits (71), Expect = 0.77
 Identities = 42/155 (27%), Positives = 61/155 (39%), Gaps = 14/155 (9%)

Query: 162 PSPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPGVSSP--AYPIPALRT 219
           P+  P  PLA P+         P   A+    A     PSP +    SP  + P+    T
Sbjct: 637 PASPPLSPLATPS------PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 690

Query: 220 APLRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPV-APSSRAARSSHIAPLLQS 278
            P +    +  P  + V PS  AS          P  P P+ AP  +   S   +P +  
Sbjct: 691 PPSQAPPSLAAPPLQ-VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSP 749

Query: 279 SSPTPP--GPTGSAAYVAV-PTPNSSSP-GPAGRP 309
           S+  PP   P  +A  + V P+P +S P  P  +P
Sbjct: 750 SATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 32/113 (28%), Positives = 48/113 (42%), Gaps = 24/113 (21%)

Query: 209 SPAYP-------IPALR----TAPLRRATGIILPARRNVLPSRGASSTRRARPLERP--- 254
           +PA+P       + ALR    T P + A   + P   + L +   S T+ ARP+  P   
Sbjct: 265 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK-ARPVPPPDNA 323

Query: 255 ATPVPVA-PSSRAARSSHIAPLLQSSSPTPPGPTGSAAYVAVPTPNSSSPGPA 306
           ATP+P   P S         PL       PP P+   +   +P+P ++ P  A
Sbjct: 324 ATPLPATLPPS--------PPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 368



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 49/185 (26%), Positives = 73/185 (39%), Gaps = 39/185 (21%)

Query: 163 SPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPGVSSPAYPIPALRTAPL 222
           +P+P+G  A P  P    ++   LPA       L   P P+ P   SP+ P P+L+T P 
Sbjct: 306 TPSPSGTKARPVPPPD--NAATPLPATLPPSPPLA-TPLPLAP--PSPSAP-PSLQTLPS 359

Query: 223 RRATGII-LPARRNVLPSRGASSTRRARPLERP---------ATPVPVAPSSRAARSSHI 272
             AT     P      P +   S +   P++ P         A P P+A SS  A +S  
Sbjct: 360 PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLG 419

Query: 273 APLLQSS---------------------SPTPPGPTGSAAYVAVPT--PNSSSPGPAGRP 309
           +P LQ++                     + TPP      A +++P   P  +S  PA  P
Sbjct: 420 SPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSP 479

Query: 310 AGAML 314
             + L
Sbjct: 480 LSSPL 484



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 49/178 (27%), Positives = 60/178 (33%), Gaps = 28/178 (15%)

Query: 157 AAEMEPSPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLP----GVSSPAY 212
           AA   P+    G L  P  P S     P  PA    L   G V    L     G+     
Sbjct: 12  AAARTPAARAPGLLT-PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70

Query: 213 PIPALRTAPLRRA-TGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSH 271
           P  A R  P R A T    PA R     RG     RA P +   +P PV+   RA+ ++ 
Sbjct: 71  PESAPRAGPTRSAGTSSRNPASRPPASGRG----ERAPPAKN-TSPGPVSSPGRASGTTR 125

Query: 272 IAPLLQSSSPTPPGPT-----------------GSAAYVAVPTPNSSSPGPAGRPAGA 312
             PL Q         T                 G+    + PTP + SP  A R   A
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183



 Score = 28.9 bits (63), Expect = 6.6
 Identities = 48/191 (25%), Positives = 65/191 (34%), Gaps = 41/191 (21%)

Query: 139 SSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGR 198
           S  + P+ I  L  L+S A     S +P  PL+    P     S    P+L    A L  
Sbjct: 478 SPLSSPLTIHPLQALSSLA-----SHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT 532

Query: 199 VPSPVLPGVSSP-----AYPI--PALRTAPLRRATGIILPARRNVLPSRGASSTRRARPL 251
            P   LP ++ P     + P+  P L T P      +  P      P     S+    P 
Sbjct: 533 PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPP 592

Query: 252 ERP-------------------ATPVPVAPSSRAARSSHIAPLLQSSSPTPPGPTGSAAY 292
           + P                   ATP P AP   A       P LQ+    PP P  S   
Sbjct: 593 QAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA------LPPLQA----PPSPPASPPL 642

Query: 293 VAVPTPNSSSP 303
             + TP+  +P
Sbjct: 643 SPLATPSPQAP 653


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 47/153 (30%), Positives = 59/153 (38%), Gaps = 18/153 (11%)

Query: 160 MEPSPTPTG--PLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPV----LPGVSSPAYP 213
           + PS TP    P +  A P     S P  P +S       + P P+    L     P   
Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 519

Query: 214 IPALRTAPLRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIA 273
            PAL T PL+      LP+     P +   S   + P+   ATP P AP   A      A
Sbjct: 520 PPALATPPLQA-----LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA------A 568

Query: 274 PLLQSSSPTPPGPTGSA-AYVAVPTPNSSSPGP 305
           PLLQ     P  PT  A      P P++S  GP
Sbjct: 569 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 601



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 46/149 (30%), Positives = 60/149 (40%), Gaps = 22/149 (14%)

Query: 162 PSPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPGVSSP--AYPIPALRT 219
           P+  P  PLA P+         P   A+    A     PSP +    SP  + P+    T
Sbjct: 412 PASPPLSPLATPS------PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 465

Query: 220 APLRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSS 279
            P +    +  P  + V PS  AS      P+   ATP P AP   AA      P LQ +
Sbjct: 466 PPSQAPPSLAAPPLQ-VPPSPPASP-----PMSPSATPPPQAPPPLAA------PPLQLA 513

Query: 280 SPTPPGPTGSAA--YVAVPTPNSSSPGPA 306
            P P  P   A     A+P+P +S PG A
Sbjct: 514 KPPPQAPPALATPPLQALPSPPASFPGQA 542



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 44/150 (29%), Positives = 60/150 (40%), Gaps = 25/150 (16%)

Query: 164 PTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPGVSS--PAYPIPALRTAP 221
           P+P+ P +    P     S P  P  S     LG   SP L    S  P+ P+  L T P
Sbjct: 343 PSPSAPPSLQTLP-----SPPATPP-SQATTSLG---SPTLQATHSFLPSPPLSPLATPP 393

Query: 222 LRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSP 281
            +    + LP      P +   S   + PL   ATP P AP++ A        LLQ+   
Sbjct: 394 PQAPPALALP------PLQAPPSPPASPPLSPLATPSPQAPNALAVH------LLQAPFS 441

Query: 282 TPPGPTGSAAY--VAVPTPNSSSPGPAGRP 309
            PP P   A +   A P  + S+  P+  P
Sbjct: 442 PPPSPPVQAPFSPPASPPVSPSATPPSQAP 471



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 43/143 (30%), Positives = 64/143 (44%), Gaps = 15/143 (10%)

Query: 164 PTPTGPLAFPAWPWSFFHSC--PGLPALSNQLAILGRVPSPVLPGVSSPAYPIPALRTAP 221
           P  + PLA P+ P +   S   P LPA  +  ++  ++ +P+     SP+ P P+L+T P
Sbjct: 298 PLSSSPLATPS-PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP-PSLQTLP 355

Query: 222 LRRATGIILPARRNVLPSRGAS-STRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSS 280
              AT           P+  A+ S   + PL   ATP P AP + A       P LQ+  
Sbjct: 356 SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA------LPPLQA-- 407

Query: 281 PTPPGPTGSAAYVAVPTPNSSSP 303
             PP P  S     + TP+  +P
Sbjct: 408 --PPSPPASPPLSPLATPSPQAP 428



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 40/151 (26%), Positives = 59/151 (39%), Gaps = 26/151 (17%)

Query: 187 PALSNQLAILGRVPSPVLPGVSSPAYPIPA-LRTAPLRRATGIILPARRNVLPSRGASST 245
           PA   + +  G +  P    +SS A P+ +  R+ P  R T    PA  +    +G  + 
Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA-PAHPSQPKPKGLQAL 280

Query: 246 RR---------ARPLERPATPVPVA-PSSRAARSSHIAPLL----QSSSPT--------- 282
           R          A P   P +  P+A PS  AA  S   P L     SSS T         
Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPL 340

Query: 283 -PPGPTGSAAYVAVPTPNSSSPGPAGRPAGA 312
            PP P+   +   +P+P ++ P  A    G+
Sbjct: 341 APPSPSAPPSLQTLPSPPATPPSQATTSLGS 371



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 49/178 (27%), Positives = 60/178 (33%), Gaps = 28/178 (15%)

Query: 157 AAEMEPSPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLP----GVSSPAY 212
           AA   P+    G L  P  P S     P  PA    L   G V    L     G+     
Sbjct: 12  AAARTPAARAPGLLT-PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70

Query: 213 PIPALRTAPLRRA-TGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSH 271
           P  A R  P R A T    PA R     RG     RA P +   +P PV+   RA+ ++ 
Sbjct: 71  PESAPRAGPTRSAGTSSRNPASRPPASGRG----ERAPPAKN-TSPGPVSSPGRASGTTR 125

Query: 272 IAPLLQSSSPTPPGPT-----------------GSAAYVAVPTPNSSSPGPAGRPAGA 312
             PL Q         T                 G+    + PTP + SP  A R   A
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 47/153 (30%), Positives = 59/153 (38%), Gaps = 18/153 (11%)

Query: 160 MEPSPTPTG--PLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPV----LPGVSSPAYP 213
           + PS TP    P +  A P     S P  P +S       + P P+    L     P   
Sbjct: 421 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 480

Query: 214 IPALRTAPLRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIA 273
            PAL T PL+      LP+     P +   S   + P+   ATP P AP   A      A
Sbjct: 481 PPALATPPLQA-----LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA------A 529

Query: 274 PLLQSSSPTPPGPTGSA-AYVAVPTPNSSSPGP 305
           PLLQ     P  PT  A      P P++S  GP
Sbjct: 530 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 562



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 46/149 (30%), Positives = 60/149 (40%), Gaps = 22/149 (14%)

Query: 162 PSPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPGVSSP--AYPIPALRT 219
           P+  P  PLA P+         P   A+    A     PSP +    SP  + P+    T
Sbjct: 373 PASPPLSPLATPS------PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 426

Query: 220 APLRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSS 279
            P +    +  P  + V PS  AS      P+   ATP P AP   AA      P LQ +
Sbjct: 427 PPSQAPPSLAAPPLQ-VPPSPPASP-----PMSPSATPPPQAPPPLAA------PPLQLA 474

Query: 280 SPTPPGPTGSAA--YVAVPTPNSSSPGPA 306
            P P  P   A     A+P+P +S PG A
Sbjct: 475 KPPPQAPPALATPPLQALPSPPASFPGQA 503



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 44/151 (29%), Positives = 64/151 (42%), Gaps = 19/151 (12%)

Query: 163 SPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPGVSS--PAYPIPALRTA 220
           +P+P+ P + P+ P S   + P  PA     A    + SP L    S  P+ P+  L T 
Sbjct: 297 TPSPSAPPS-PSAPPSL-QTLPSPPATPPSQATTS-LGSPTLQATHSFLPSPPLSPLATP 353

Query: 221 PLRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSS 280
           P +    + LP      P +   S   + PL   ATP P AP++ A        LLQ+  
Sbjct: 354 PPQAPPALALP------PLQAPPSPPASPPLSPLATPSPQAPNALAVH------LLQAPF 401

Query: 281 PTPPGPTGSAAY--VAVPTPNSSSPGPAGRP 309
             PP P   A +   A P  + S+  P+  P
Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSATPPSQAP 432



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 43/172 (25%), Positives = 60/172 (34%), Gaps = 32/172 (18%)

Query: 164 PTPTGPLAF------PAWPWSFFHSCPGLPALSNQLAILGRVPSPVL------PGVSSPA 211
           P+P+ P +       PA P S   +  G P L    + L   PSP L      P  + PA
Sbjct: 304 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL---PSPPLSPLATPPPQAPPA 360

Query: 212 YPIPALRTAPLRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSH 271
             +P L+  P   A+  + P      PS  A +      L+ P +P P  P         
Sbjct: 361 LALPPLQAPPSPPASPPLSPL---ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417

Query: 272 IAPLLQSSSP--------------TPPGPTGSAAYVAVPTPNSSSPGPAGRP 309
             P+  S++P               PP P  S       TP   +P P   P
Sbjct: 418 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 469



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 51/169 (30%), Positives = 67/169 (39%), Gaps = 28/169 (16%)

Query: 137 GPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPAWPWSFFHSCPGL-PALSNQLAI 195
           GPS+R  P          + A   +P P     L  P        + P L P  S+ LA 
Sbjct: 247 GPSARGTP---------RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA- 296

Query: 196 LGRVPSPVLPGVSSPAYPIPALRTAPLRRATGIILPARRNVLPSRGAS-STRRARPLERP 254
               PSP  P   SP+ P P+L+T P   AT           P+  A+ S   + PL   
Sbjct: 297 ---TPSPSAP--PSPSAP-PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 350

Query: 255 ATPVPVAPSSRAARSSHIAPLLQSSSPTPPGPTGSAAYVAVPTPNSSSP 303
           ATP P AP + A       P LQ+    PP P  S     + TP+  +P
Sbjct: 351 ATPPPQAPPALA------LPPLQA----PPSPPASPPLSPLATPSPQAP 389



 Score = 32.0 bits (71), Expect = 0.77
 Identities = 31/127 (24%), Positives = 50/127 (39%), Gaps = 8/127 (6%)

Query: 187 PALSNQLAILGRVPSPVLPGVSSPAYPIPA-LRTAPLRRATGIILPARRNVLPSRGASST 245
           PA   + +  G +  P    +SS A P+ +  R+ P  R T      R    PS+     
Sbjct: 213 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT-----PRAPAHPSQPKPKG 267

Query: 246 RRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGPTGSAAYVAVPTPNSSSPGP 305
            +A  L  P    P   ++ A      +PL   S   PP P+   +   +P+P ++ P  
Sbjct: 268 LQA--LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQ 325

Query: 306 AGRPAGA 312
           A    G+
Sbjct: 326 ATTSLGS 332


>gi|30795242 aryl hydrocarbon receptor nuclear translocator isoform
           3 [Homo sapiens]
          Length = 774

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 8/100 (8%)

Query: 5   KEPSGSDGESDGPIDVGQEGQLSQMARPLSTPSSSQMQARKKRRGIIEKRRRDRINSSLS 64
           K   G D + DG      EG    +       S+ + +  ++    IE+RRR+++ + ++
Sbjct: 42  KRRPGLDFDDDG------EGNSKFLRCDDDQMSNDKERFARENHSEIERRRRNKMTAYIT 95

Query: 65  ELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGT 104
           EL  +VPT      + K +K  +L+M V H+K L  TG T
Sbjct: 96  ELSDMVPTC--SALARKPDKLTILRMAVSHMKSLRGTGNT 133


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 50/190 (26%), Positives = 75/190 (39%), Gaps = 31/190 (16%)

Query: 151 SHLNSYAAEMEPSPTPTGPLAFP--AWPWSFFHSCP--GLPALSNQLAILGRVPSPVLP- 205
           +HL     + +   +P GPL       P++F       GL  L+     LG +P+   P 
Sbjct: 230 THLRKQCGQADTYQSPLGPLFSQDSGRPFTFQSDLALLGLENLTTATPALGSLPAGRGPR 289

Query: 206 GVSSPAYPIPALRTAPLRR---------ATGIILPARRN-------VLPSRGASSTRRAR 249
           G  +PA P    RT+P            A   +LPA+ +       +LP+    STR  R
Sbjct: 290 GTVAPATPTKPQRTSPTNPHQHMAVGGPAQTPLLPAKLSASNALDPMLPASVGGSTRTPR 349

Query: 250 PLERP------ATPVPVA-PSSRAARSSHIAPLLQSSSPTPPGPTGSAAYVAVPTPNSSS 302
           P          AT +P + P+  +A S+ I P+    SP P   T  +++     P    
Sbjct: 350 PAAAQPSQKITATKIPKSLPTKPSAPSTSIVPI---KSPHPTQKTAPSSFTKSALPTQKQ 406

Query: 303 PGPAGRPAGA 312
             P  RP  A
Sbjct: 407 VPPTSRPVPA 416



 Score = 32.3 bits (72), Expect = 0.59
 Identities = 42/166 (25%), Positives = 60/166 (36%), Gaps = 39/166 (23%)

Query: 173 PAWPWSFFHSCPGLPALSNQLAILG------RVPSPVLPGVSSPAYPIPALRTAPLRRAT 226
           PA   +  H  P   ALS+  A         R P+ ++P  S  + P    RTAP     
Sbjct: 471 PASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVPPTSGTSTP----RTAPAVPTP 526

Query: 227 GIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGP 286
           G      +  +   G+ ++++A P   P  PVP+ P  +AAR   ++ L    SP  P P
Sbjct: 527 GSAPTGSKKPI---GSEASKKAGPKSSPRKPVPLRPG-KAARDVPLSDLTTRPSPRQPQP 582

Query: 287 TGSAAYVAV----------PTPNSSS---------------PGPAG 307
           +       V          P P SS                 GP G
Sbjct: 583 SQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPG 628



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 4/94 (4%)

Query: 213 PIPALRTAPLRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHI 272
           P P  +TAP    T   LP ++ V P+      R +RP E+P    P  P      +  +
Sbjct: 385 PHPTQKTAP-SSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPL 443

Query: 273 APLLQSSSPTPPGPTGSAAYVAVPTPNSSSPGPA 306
            P   SS    P    + A +   T ++S P  A
Sbjct: 444 PPTTSSSKKPIPTLARTEAKI---TSHASKPASA 474



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 35/125 (28%), Positives = 45/125 (36%), Gaps = 18/125 (14%)

Query: 202 PVLPGVSSPAYPIPALRTAPLRRATGIILPARRNVL-------------PSRGASSTRRA 248
           P+ P  SS   PIP L     +  +    PA                  P+    STR  
Sbjct: 442 PLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRST 501

Query: 249 RPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGPTGS-AAYVAVPTPNSSSPGPAG 307
           RP   PAT VP    +   R++   P   S+      P GS A+  A P  +   P P  
Sbjct: 502 RP---PATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPKSSPRKPVPL- 557

Query: 308 RPAGA 312
           RP  A
Sbjct: 558 RPGKA 562


>gi|163965366 nascent polypeptide-associated complex alpha subunit
           isoform a [Homo sapiens]
          Length = 2078

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 47/153 (30%), Positives = 61/153 (39%), Gaps = 23/153 (15%)

Query: 165 TPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPGVSSPAYPIPALRTAPLRR 224
           TP G L+ P  P         LP   N L+  G   SP      SP  P P  + AP   
Sbjct: 819 TPIGNLSSPVSPVE----ASFLP--ENSLSFQGSKDSPAT--THSPTPPSP--KGAPTPS 868

Query: 225 AT------GIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQS 278
           A       G+ LP +    PS          P E PATP P    + +  SS  +P    
Sbjct: 869 AVTPLSPKGVTLPPKETPTPS----VVNLPFPKEGPATPAPKQAPALSMTSS--SPKKAR 922

Query: 279 SSPTPPGPTGSAAYVAVPTPNSSS-PGPAGRPA 310
           ++P P G   S +    PTP +++ P P G PA
Sbjct: 923 ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPA 955



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 54/189 (28%), Positives = 73/189 (38%), Gaps = 28/189 (14%)

Query: 136  EGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTG------PLAFPAWPWSFFHSCPGLPAL 189
            EGP++ A P +   LS  +S   +   +P P G      P   P  P +   S  G PA 
Sbjct: 898  EGPATPA-PKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT 956

Query: 190  -SNQLAILGRVPSPVLPGVSSPAYPIPALRTAPLRRATGIILPARRNVLPSRGASSTRRA 248
             S + A      +P  P    PA P P     P         PA     P  G ++    
Sbjct: 957  PSPKWAPTPPAATPPSPK-GGPATPSPKGAPTP---------PAATPPSPKGGPATPS-- 1004

Query: 249  RPLERPATPVPVAPSSRAARSSHIAPLLQSSSP--TPPGPTGSAAYVAVP-----TPNSS 301
             P   P  P    PS + + ++   P   S+ P  TPP P GS A   +P     TP ++
Sbjct: 1005 -PKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAAT 1063

Query: 302  SPGPAGRPA 310
             P P G PA
Sbjct: 1064 LPSPKGGPA 1072



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 46/177 (25%), Positives = 61/177 (34%), Gaps = 16/177 (9%)

Query: 138  PSSRADPVR--IRLLSH-----LNSYAAEMEPSPTPTGPLAFPAWPWSFFHSCPGLPALS 190
            PSSR DP+     LLS      L    A + P+ T   P   PA P       P  P+  
Sbjct: 1520 PSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTP--KEAPATPSSK 1577

Query: 191  NQLAILGRVPSPVLPGVSSPAYPIPALRTAPLRRATGIILPARRNVLPSRG-ASSTRRAR 249
               +     PS      S     IP   T+P  +      PA     P +G A+   +  
Sbjct: 1578 EASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP-PAVTPPSPEKGPATPAPKGT 1636

Query: 250  PLERPATPV-----PVAPSSRAARSSHIAPLLQSSSPTPPGPTGSAAYVAVPTPNSS 301
            P   P TP      P +P+S   +     P      P   GPT     +  P P S+
Sbjct: 1637 PTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPEST 1693



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 36/156 (23%), Positives = 56/156 (35%), Gaps = 8/156 (5%)

Query: 158  AEMEPSPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPGVSSPAY---PI 214
            A   P   PT P A P  P       P  P            P  +  G+++P +   P 
Sbjct: 1233 ATPSPKGAPTTPAATPPSP----KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPN 1288

Query: 215  PALRTAPLRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAP 274
            PA+ T P  +      P +    P      + +  P   P    P  P+     S    P
Sbjct: 1289 PAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP-SPKGTP 1347

Query: 275  LLQSSSPTPPGPTGSAAYVAVPTPNSSSPGPAGRPA 310
             L +++P+  G   + +    PTP +++P   G PA
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPA 1383



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 49/192 (25%), Positives = 68/192 (35%), Gaps = 33/192 (17%)

Query: 138  PSSRADPVRIRLLSHLNSYAAEMEPSP----TPTGPLAFPAWPWSFFHSCPGLPALSNQL 193
            PSS+ DP     L  +   + +  P+P    T + P   PA P       P LPA     
Sbjct: 1459 PSSKGDPT----LPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM--GAPTLPA----- 1507

Query: 194  AILGRVPSPVLPGVSSPAYPIPALRTAPLRRATGIILPARRNVLPSRGASSTRRA----R 249
             ++   P  V    SS   PI    T   ++    + P    + P+    S ++      
Sbjct: 1508 -VIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPT 1566

Query: 250  PLERPATPVPVAPSSRAA------------RSSHIAPLLQSSSPTPPGPTGSAAYVAVPT 297
            P E PATP     SS  A            +   I P + S SP    PT  A     P 
Sbjct: 1567 PKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE-APTPPAVTPPSPE 1625

Query: 298  PNSSSPGPAGRP 309
               ++P P G P
Sbjct: 1626 KGPATPAPKGTP 1637



 Score = 36.6 bits (83), Expect = 0.031
 Identities = 51/180 (28%), Positives = 68/180 (37%), Gaps = 21/180 (11%)

Query: 138  PSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILG 197
            P   + P      S   S AA   P   PT P A    P       P  P+L        
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP----KGGPATPSLKGAPTPPA 1084

Query: 198  RVPSPVLPGVSSPA---YPIPALRTAPLRRATGIILPARRNVLPSRGASSTRRARPLERP 254
              P     G ++P+    P+P   T P  +  G+  P      P +GA +T  A P    
Sbjct: 1085 ATPPSPKGGPATPSPKGAPMPPAATPPSPKG-GLATP------PHKGAPTTPAATPPSPK 1137

Query: 255  ---ATPVPV-APSSRAARSSHIAPLLQSSSPTPPG-PTGSAAYVAVPTPNSSSPGPAGRP 309
               ATP P  AP++ AA     +P    ++P P G PT  AA    P    ++P P G P
Sbjct: 1138 GGLATPPPKGAPTTPAATPP--SPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 44/165 (26%), Positives = 57/165 (34%), Gaps = 29/165 (17%)

Query: 158  AEMEPSPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVL-PGVSSP-AYPIP 215
            A   P+ TP  P   PA P       P  PA +         PSP   P   SP   P P
Sbjct: 962  APTPPAATPPSPKGGPATPSP--KGAPTPPAATP--------PSPKGGPATPSPKGAPTP 1011

Query: 216  ALRTAPLRRATGIILPARRNVL-------PSRGASSTRRARPLERPATPVPVAPSSRAAR 268
               T P  + +    P  +          PS   S      P   P TP    PS +   
Sbjct: 1012 PAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGP 1071

Query: 269  SSHIAPLLQSS----SPTPPGPTGSAAYVAVPTPNSSSPGPAGRP 309
            ++   P L+ +    + TPP P G  A    P+P  +   PA  P
Sbjct: 1072 AT---PSLKGAPTPPAATPPSPKGGPA---TPSPKGAPMPPAATP 1110



 Score = 33.5 bits (75), Expect = 0.27
 Identities = 52/193 (26%), Positives = 73/193 (37%), Gaps = 25/193 (12%)

Query: 138  PSSRADPVRIRL--LSHLNSYAAEM--EPSPTPT-GPLAFPAWPWSFFHSCPGLPALSNQ 192
            PS + DP    +  LS   + A  +  E + TP+ G L  PA         P   A    
Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG 1455

Query: 193  LAILGRVPSPVLPGVSSPAYPIPALRTAPLRRATGIILPARRNVLPSRGASSTRRARPLE 252
             A       P LP V+ P+   P    AP + AT    P +    P+   + T    P  
Sbjct: 1456 PATPSSKGDPTLPAVTPPS---PKEPPAPKQVATSSS-PKKAPATPAPMGAPTL---PAV 1508

Query: 253  RPATP--VPVAPSSRAARSSHIAPLLQSSSPT---------PPGPT--GSAAYVAVPTPN 299
             P++P  VP  PSSR    +  A LL   +P          PP  T        A+PTP 
Sbjct: 1509 IPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK 1568

Query: 300  SSSPGPAGRPAGA 312
             +   P+ + A +
Sbjct: 1569 EAPATPSSKEASS 1581



 Score = 33.1 bits (74), Expect = 0.35
 Identities = 30/126 (23%), Positives = 45/126 (35%), Gaps = 6/126 (4%)

Query: 193 LAILGRVPSPVLPGVSSPAYPIPALRTA-----PLRRATGIILPARRNVLPSRGASSTRR 247
           L  L   PSP+   VS      P  + +     P+   +  + P   + LP    S    
Sbjct: 787 LTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGS 846

Query: 248 ARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGPTGSAAYVAVPTPNSSSPGPAG 307
                   +P P +P   A   S + PL       PP  T + + V +P P      PA 
Sbjct: 847 KDSPATTHSPTPPSPKG-APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAP 905

Query: 308 RPAGAM 313
           + A A+
Sbjct: 906 KQAPAL 911



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 38/151 (25%), Positives = 55/151 (36%), Gaps = 23/151 (15%)

Query: 166  PTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVL-PGVSSPAYPIPALRTAPLRR 224
            PT P A P        S  G PA++         PSP   P + SP     +    PL  
Sbjct: 1369 PTPPAATP--------SHKGGPAMTP--------PSPKRGPAIPSPKGDPTSPAVIPLSP 1412

Query: 225  ATGIILPARRN--VLPSRGASSTRRARPL---ERPATPVPVA-PSSRAARSSHIAPLLQS 278
                  P  R     PS+G  +     P+   + PAT  P   P++ +++     P +  
Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP 1472

Query: 279  SSPTPPGPTGSAAYVAVPTPNSSSPGPAGRP 309
             SP  P      A  + P    ++P P G P
Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAP 1503



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 37/150 (24%), Positives = 56/150 (37%), Gaps = 18/150 (12%)

Query: 162  PSPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPGVSSPAYPIPALRTAP 221
            P  TPT P   P  P S   S     +++ ++       S  LP    P   +  +  AP
Sbjct: 1633 PKGTPTSP---PVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPT-ALKEVLVAP 1688

Query: 222  LRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIA-----PLL 276
               +T II        P+R    T+++     P  P P A +      S +A     P+ 
Sbjct: 1689 APESTPII------TAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQ 1742

Query: 277  QSSSPTPPGPTGS---AAYVAVPTPNSSSP 303
            + SS T  G   S      +A P   +S+P
Sbjct: 1743 KDSSKTAKGKDASHSPKGPLAPPESKASTP 1772



 Score = 28.9 bits (63), Expect = 6.6
 Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 10/93 (10%)

Query: 213 PIPALRTAPLRRATGIILP---ARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARS 269
           P  A  T P   AT   LP   A   VLP   A S   A     P  P P +P+ +    
Sbjct: 2   PGEATETVP---ATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPL 58

Query: 270 SHIAPLLQSSSPTPPGPTGSAAYVAVPTPNSSS 302
           S        +SP P   T ++  + VP P SSS
Sbjct: 59  S----AANQASPFPSPSTIASTPLEVPFPQSSS 87


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,442,699
Number of Sequences: 37866
Number of extensions: 938027
Number of successful extensions: 9742
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 154
Number of HSP's successfully gapped in prelim test: 810
Number of HSP's that attempted gapping in prelim test: 6993
Number of HSP's gapped (non-prelim): 3086
length of query: 328
length of database: 18,247,518
effective HSP length: 103
effective length of query: 225
effective length of database: 14,347,320
effective search space: 3228147000
effective search space used: 3228147000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.