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Search of human proteins with 75709184
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|75709184 contactin 3 [Homo sapiens]
(1028 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|75709184 contactin 3 [Homo sapiens] 2080 0.0
gi|28373122 contactin 4 isoform a precursor [Homo sapiens] 1416 0.0
gi|7657361 contactin 6 [Homo sapiens] 1301 0.0
gi|28373129 contactin 5 isoform short [Homo sapiens] 1139 0.0
gi|7657359 contactin 5 isoform long [Homo sapiens] 1130 0.0
gi|28373126 contactin 4 isoform c precursor [Homo sapiens] 921 0.0
gi|4827022 contactin 2 precursor [Homo sapiens] 899 0.0
gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens] 877 0.0
gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens] 876 0.0
gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo... 409 e-114
gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo ... 409 e-114
gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo s... 409 e-114
gi|27894376 cell adhesion molecule with homology to L1CAM precur... 375 e-103
gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 374 e-103
gi|81158226 neuronal cell adhesion molecule isoform A precursor ... 365 e-100
gi|237858679 neurofascin isoform 3 precursor [Homo sapiens] 363 e-100
gi|89903008 neurofascin isoform 4 precursor [Homo sapiens] 363 e-100
gi|237858677 neurofascin isoform 2 precursor [Homo sapiens] 355 2e-97
gi|28373124 contactin 4 isoform b precursor [Homo sapiens] 339 9e-93
gi|222352127 sidekick 2 [Homo sapiens] 331 2e-90
gi|237858675 neurofascin isoform 1 precursor [Homo sapiens] 330 4e-90
gi|119220552 sidekick 1 [Homo sapiens] 301 2e-81
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 242 1e-63
gi|237858682 neurofascin isoform 6 precursor [Homo sapiens] 226 7e-59
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa... 225 1e-58
gi|237858680 neurofascin isoform 5 precursor [Homo sapiens] 224 3e-58
gi|157311649 neogenin homolog 1 [Homo sapiens] 220 5e-57
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 211 2e-54
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 211 2e-54
gi|19743806 roundabout 1 isoform b [Homo sapiens] 203 8e-52
>gi|75709184 contactin 3 [Homo sapiens]
Length = 1028
Score = 2080 bits (5388), Expect = 0.0
Identities = 1028/1028 (100%), Positives = 1028/1028 (100%)
Query: 1 MMFPWKQLILLSFIGCLGGELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHY 60
MMFPWKQLILLSFIGCLGGELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHY
Sbjct: 1 MMFPWKQLILLSFIGCLGGELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHY 60
Query: 61 RWQLNGSDIDMSMEHRYKLNGGNLVVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAY 120
RWQLNGSDIDMSMEHRYKLNGGNLVVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAY
Sbjct: 61 RWQLNGSDIDMSMEHRYKLNGGNLVVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAY 120
Query: 121 LENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGH 180
LENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGH
Sbjct: 121 LENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGH 180
Query: 181 LYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAA 240
LYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAA
Sbjct: 181 LYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAA 240
Query: 241 KGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAE 300
KGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAE
Sbjct: 241 KGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAE 300
Query: 301 NSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVL 360
NSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVL
Sbjct: 301 NSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVL 360
Query: 361 EERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQ 420
EERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQ
Sbjct: 361 EERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQ 420
Query: 421 VQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCM 480
VQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCM
Sbjct: 421 VQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCM 480
Query: 481 AENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGA 540
AENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGA
Sbjct: 481 AENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGA 540
Query: 541 LADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGP 600
LADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGP
Sbjct: 541 LADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGP 600
Query: 601 PENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTA 660
PENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTA
Sbjct: 601 PENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTA 660
Query: 661 TVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVIT 720
TVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVIT
Sbjct: 661 TVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVIT 720
Query: 721 WDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGV 780
WDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGV
Sbjct: 721 WDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGV 780
Query: 781 YNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEV 840
YNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEV
Sbjct: 781 YNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEV 840
Query: 841 RYWNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKK 900
RYWNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKK
Sbjct: 841 RYWNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKK 900
Query: 901 TPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSA 960
TPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSA
Sbjct: 901 TPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSA 960
Query: 961 ELVLPIKEDYIIEVKATTDGGDGTSSEQIRIPRITSMDARGSTSAISNVHPMSSYMPIVL 1020
ELVLPIKEDYIIEVKATTDGGDGTSSEQIRIPRITSMDARGSTSAISNVHPMSSYMPIVL
Sbjct: 961 ELVLPIKEDYIIEVKATTDGGDGTSSEQIRIPRITSMDARGSTSAISNVHPMSSYMPIVL 1020
Query: 1021 FLIVYVLW 1028
FLIVYVLW
Sbjct: 1021 FLIVYVLW 1028
>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
Length = 1026
Score = 1416 bits (3665), Expect = 0.0
Identities = 664/1023 (64%), Positives = 839/1023 (82%), Gaps = 4/1023 (0%)
Query: 1 MMFPWKQLILLSFIGCLGGELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHY 60
M PW+ L+L SFI CL + L GP+FI+EPS +FP+ SE+KK+ L+CE +GNP PH
Sbjct: 1 MRLPWELLVLQSFILCLADDSTLHGPIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHI 60
Query: 61 RWQLNGSDIDMSMEHRYKLNGGNLVVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAY 120
RW+LNG+D+D M+ RY + G+L++ NPN+ D GTYQC ATNS GTIVSREAKLQFAY
Sbjct: 61 RWKLNGTDVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAY 120
Query: 121 LENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGH 180
L+NFKT+ RSTVSVR GQG+VLLCGPPPHSGELSYAWIFNEYPS+ +D+RRFVSQETG+
Sbjct: 121 LDNFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPSY--QDNRRFVSQETGN 178
Query: 181 LYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAA 240
LYI+KVE SDVGNYTCVVT+ VTN +VLG PTPL+LR+DGVMGEYEPKIEVQFPET+P A
Sbjct: 179 LYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTA 238
Query: 241 KGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAE 300
KG+TVKLECFALGNP+P I WRR+DG P + K + K +G+LEIPNFQQEDAG YEC+AE
Sbjct: 239 KGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKSNGILEIPNFQQEDAGLYECVAE 298
Query: 301 NSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVL 360
NSRGKNVARG+LT+YA+P+W+Q I D+ +A+E++++WEC+A+G+PKP+Y+WLKNG L+
Sbjct: 299 NSRGKNVARGQLTFYAQPNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGEPLLT 358
Query: 361 EERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQ 420
+R QIE G L I+ ++++D+GM+QC+AENKHG+++S+AEL V+A PDFS+ +K++
Sbjct: 359 RDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTL 418
Query: 421 VQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCM 480
V+VG V ++CKP+ASP+ + +WKKG ++E+ERI++ DG L+I NVTK+DAG+YTC+
Sbjct: 419 VKVGGEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCI 478
Query: 481 AENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGA 540
A N FG A+ T +LVV +PTR+ + PS+MDV+VGES++LPCQV HD LDI+FTW FNG
Sbjct: 479 ATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGH 538
Query: 541 LADFKKDGSHFEKVGG-SSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPG 599
L DF +DG HFE+VGG S+GDLMIRNIQLKH+GKYVCMVQT VD +S+AADLIVRG PG
Sbjct: 539 LIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPG 598
Query: 600 PPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHT 659
PPE V +DEITDTTAQLSW+ G DNHSP+ Y IQARTPFSVGWQ V+TVPE+IDGKT T
Sbjct: 599 PPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFT 658
Query: 660 ATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVI 719
ATVV LNPWVEYEFR VA+N IG GEPS PSEK RTEEA+PEV P+ V+GGGGS+SELVI
Sbjct: 659 ATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVI 718
Query: 720 TWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVG 779
TW+ VPEELQNG GFGYVVAFRP G W+ TV+ S D RYVFRNES+ P+SP+EVKVG
Sbjct: 719 TWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYVFRNESVHPFSPFEVKVG 778
Query: 780 VYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYE 839
V+NNKGEGPFSP T V+SAEEEPT P+ + A SLS+++IEV W + P + + G + GYE
Sbjct: 779 VFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWAS-PLEKNRGRIQGYE 837
Query: 840 VRYWNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTK 899
V+YW KEE++ K++ GN+TS ++ LK ++ Y+ AV+AYNSAG GP SATVNVTT+
Sbjct: 838 VKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTR 897
Query: 900 KTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTS 959
K PPSQPPGN++WN++D+K++LNW+QVKA++NESEV GYKV YR + Q++ V+ TNKTS
Sbjct: 898 KPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTS 957
Query: 960 AELVLPIKEDYIIEVKATTDGGDGTSSEQIRIPRITSMDARGSTSAISNVHPMSSYMPIV 1019
EL LP EDYIIE+K +DGGDG+SSEQIRIP+I++ ARGS ++ SN +S+ I+
Sbjct: 958 VELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGSGASTSNACTLSAISTIM 1017
Query: 1020 LFL 1022
+ L
Sbjct: 1018 ISL 1020
>gi|7657361 contactin 6 [Homo sapiens]
Length = 1028
Score = 1301 bits (3366), Expect = 0.0
Identities = 608/1022 (59%), Positives = 789/1022 (77%), Gaps = 4/1022 (0%)
Query: 1 MMFPWKQLILLSFIGCLGGELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHY 60
M WK +ILL I G+ LL P+F +EP + IFP+ ++ L+C A G PSPHY
Sbjct: 1 MRLLWKLVILLPLINSSAGDGLLSRPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHY 60
Query: 61 RWQLNGSDIDMSMEHRYKLNGGNLVVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAY 120
RW+ NG+DID +M + Y+L+GG+L + +P+ + D G YQC ATN LGTI+SR+AKLQFAY
Sbjct: 61 RWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAY 120
Query: 121 LENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGH 180
+E+F+TK RSTVSVREGQGVVLLCGPPPH G+LSYAW FN+ P +V+ED+RRFVSQETG+
Sbjct: 121 IEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGN 180
Query: 181 LYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAA 240
LYI+KVEPSDVGNYTC +T+ V G PTPLV R+DGVMGEYEPKIEV+FPET+ AA
Sbjct: 181 LYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAA 240
Query: 241 KGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAE 300
K S+VKLECFALGNP+P I+WRR DG P K+K K +LEIPNFQQED G YECIA
Sbjct: 241 KDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIAS 300
Query: 301 NSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVL 360
N RG+N+A+G+L +YA P W Q I++ +++ D+L WEC+ASGKP P Y WLKNG L
Sbjct: 301 NLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNP 360
Query: 361 EERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQ 420
EER QIENG L I+ L+V+DSG++QC AENK+ ++Y++AEL+V+ASAPDFSK+P+KK
Sbjct: 361 EERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSF 420
Query: 421 VQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCM 480
VQVG + + CKP A PRA SWK+G ++++ +RI LL DG LKI N+T++DAG+YTC+
Sbjct: 421 VQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCI 480
Query: 481 AENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGA 540
A NQFG A T L+V E T IT+ PS MDV+VGES++LPCQV HDP ++++F W+FNG
Sbjct: 481 ATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGD 540
Query: 541 LADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGP 600
+ D KK +HFE++GG S GDLMIRNIQL HSGKY+C VQT ++S+S+ AD+IVRG PGP
Sbjct: 541 VIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGP 600
Query: 601 PENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTA 660
PE+V+V++I+ TT+QLSW+ G DN+SP+ ++IQ RTPFSVGWQ V TVPE+++GKT+ A
Sbjct: 601 PEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNA 660
Query: 661 TVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVIT 720
TVV L+PWVEYEFRVVA N IG GEPS PSE +RT+ +VP V P ++GGGGSRSELVIT
Sbjct: 661 TVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVIT 720
Query: 721 WDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGV 780
W+ +PEELQNGEGFGY++ FRP+G TTW + V+S ++ R+V+RNESI+P SP+EVKVGV
Sbjct: 721 WESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGV 780
Query: 781 YNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEV 840
YNN+GEG S VT V+S E+EP +AP S S S+SE+EVSWN I W + G +LGYEV
Sbjct: 781 YNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEV 840
Query: 841 RYWNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKK 900
YW KE K++V+GN T+ + GLK+N Y+ +VRAYN+AG GP S VNVTTKK
Sbjct: 841 LYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKK 900
Query: 901 TPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSA 960
+PPSQPP N+ W T++K+ LNWE VK MENESEV GYK+ YR + Q+ +L TN TSA
Sbjct: 901 SPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSA 960
Query: 961 ELVLPIKEDYIIEVKATTDGGDGTSSEQIRIPRITSMDARGSTSAISNVHPMSSYMPIVL 1020
EL++P +EDY+IE++ +DGGDG+SSE+IRIP+++S+ +RG I + P + ++ IV+
Sbjct: 961 ELLVPFEEDYLIEIRTVSDGGDGSSSEEIRIPKMSSLSSRG----IQFLEPSTHFLSIVI 1016
Query: 1021 FL 1022
+
Sbjct: 1017 VI 1018
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 1139 bits (2946), Expect = 0.0
Identities = 559/1028 (54%), Positives = 725/1028 (70%), Gaps = 8/1028 (0%)
Query: 1 MMFPWKQLILLSFIGCLGGELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHY 60
M WK ++ LS CL E + GPVF++EP + IFP S++KK+ L+CE RGNP P Y
Sbjct: 1 MASSWKLMLFLSVTMCLS-ESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSY 59
Query: 61 RWQLNGSDIDMSMEHRYKLNGGNLVVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAY 120
RW NG++ID+ ++RY L G ++ NP+ D+G YQC ATN++G+I+SREA LQFAY
Sbjct: 60 RWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQCLATNTVGSILSREATLQFAY 119
Query: 121 LENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGH 180
L NF + RS VSVREGQGVVL+C PPPHS E+ Y+W+FNE+PSFV EDSRRF+SQETG+
Sbjct: 120 LGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGN 179
Query: 181 LYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAA 240
LYISKV+ SDVG+Y C+V + VTNARVL PTPL LR+DGVMGEYEPKIEV FP T+ AA
Sbjct: 180 LYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAA 239
Query: 241 KGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAE 300
KG+TVK+ECFALGNP+P I W + +G SK +LRK VLEIPN Q +DAG YEC AE
Sbjct: 240 KGTTVKMECFALGNPVPTITWMKVNGY-IPSKARLRKSQAVLEIPNVQLDDAGIYECRAE 298
Query: 301 NSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVL 360
NSRGKN RG+L Y PHWV+ + D ++ L WEC+A+GKP+P+YRWLKNG L
Sbjct: 299 NSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSP 358
Query: 361 EERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQ 420
+ R ++ NG L I N++ +D+GM+QC+AENK+G +Y+SAELK++ASAP F+ N +KK +
Sbjct: 359 QSRVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTII 418
Query: 421 VQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCM 480
V V ++CKP+ SP+ SWKKGD +V+E++RI++L DG L+I N +K+D G Y C
Sbjct: 419 VTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCR 478
Query: 481 AENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGA 540
EN FG A L V EPTRI L P +++VGES++L C+ HD LD+ F W G
Sbjct: 479 GENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQ 538
Query: 541 LADFKKDGSHFEKVGG-SSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPG 599
DF+++G HFE + +SS DLMIRNI L H+G+Y C VQT DSVS A+L+VRG PG
Sbjct: 539 PIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPG 598
Query: 600 PPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHT 659
PP V V+EIT++TA LSW DNHSP+ SY++QAR+PFS+GWQTV TVPE+I G +
Sbjct: 599 PPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGDMES 658
Query: 660 ATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVI 719
A V+LNPWVEYEFRVVA+N IG G+PS PS +RT EAVP+ P+ V+G G R ELVI
Sbjct: 659 AMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVI 718
Query: 720 TWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVG 779
W+PV EE QNGEGFGY+VAFRP G W + +VTS + ++++R+ES+ P +P+EVKVG
Sbjct: 719 AWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVG 778
Query: 780 VYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYE 839
VYNNKG+GPFS + + SAE EP+ AP+ V A S+S SEI V+W I K S G G+E
Sbjct: 779 VYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHI--KESLGRPQGFE 836
Query: 840 VRYWNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTK 899
V YW +E+++ +K GNE+ L GL+ N Y+ VRAYN AG GP S+ V+ TTK
Sbjct: 837 VGYWKDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTK 896
Query: 900 KTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTS 959
K+PPSQ P N+ W ++V L WE V + NESEV GYKVFYR +N QV+ T K
Sbjct: 897 KSPPSQAPSNLRWEQQGSQVSLGWEPVIPLANESEVVGYKVFYRQEGHSNSQVIETQKLQ 956
Query: 960 AELVLPIKEDYIIEVKATTDGGDGTSSEQIRIPRITSMDARGSTSAISNVHPMSSYMPIV 1019
A + LP YIIEV+A ++GGDGT+S QIR+P S TSA S +H +S+ V
Sbjct: 957 AVVPLPDAGVYIIEVRAYSEGGDGTASSQIRVP---SYSGGKITSAQSTLHSLSTSSSSV 1013
Query: 1020 LFLIVYVL 1027
L+ ++
Sbjct: 1014 TLLLALMI 1021
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 1130 bits (2924), Expect = 0.0
Identities = 551/1004 (54%), Positives = 714/1004 (71%), Gaps = 7/1004 (0%)
Query: 25 GPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDIDMSMEHRYKLNGGNL 84
GPVF++EP + IFP S++KK+ L+CE RGNP P YRW NG++ID+ ++RY L G
Sbjct: 98 GPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTF 157
Query: 85 VVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLC 144
++ NP+ D+G YQC ATN++G+I+SREA LQFAYL NF + RS VSVREGQGVVL+C
Sbjct: 158 IISNPSEAKDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMC 217
Query: 145 GPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVVTSMVTN 204
PPPHS E+ Y+W+FNE+PSFV EDSRRF+SQETG+LYISKV+ SDVG+Y C+V + VTN
Sbjct: 218 SPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTN 277
Query: 205 ARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRS 264
ARVL PTPL LR+DGVMGEYEPKIEV FP T+ AAKG+TVK+ECFALGNP+P I W +
Sbjct: 278 ARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKV 337
Query: 265 DGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLI 324
+G SK +LRK VLEIPN Q +DAG YEC AENSRGKN RG+L Y PHWV+ +
Sbjct: 338 NGY-IPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKL 396
Query: 325 KDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIENGALTISNLSVTDSGMF 384
D ++ L WEC+A+GKP+P+YRWLKNG L + R ++ NG L I N++ +D+GM+
Sbjct: 397 NDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMY 456
Query: 385 QCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWK 444
QC+AENK+G +Y+SAELK++ASAP F+ N +KK + V V ++CKP+ SP+ SWK
Sbjct: 457 QCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWK 516
Query: 445 KGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITL 504
KGD +V+E++RI++L DG L+I N +K+D G Y C EN FG A L V EPTRI L
Sbjct: 517 KGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIEL 576
Query: 505 APSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGG-SSSGDLM 563
P +++VGES++L C+ HD LD+ F W G DF+++G HFE + +SS DLM
Sbjct: 577 TPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLM 636
Query: 564 IRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKD 623
IRNI L H+G+Y C VQT DSVS A+L+VRG PGPP V V+EIT++TA LSW D
Sbjct: 637 IRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITESTATLSWSPAAD 696
Query: 624 NHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGG 683
NHSP+ SY++QAR+PFS+GWQTV TVPE+I G +A V+LNPWVEYEFRVVA+N IG
Sbjct: 697 NHSPISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRVVATNPIGT 756
Query: 684 GEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPL 743
G+PS PS +RT EAVP+ P+ V+G G R ELVI W+PV EE QNGEGFGY+VAFRP
Sbjct: 757 GDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPN 816
Query: 744 GVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPT 803
G W + +VTS + ++++R+ES+ P +P+EVKVGVYNNKG+GPFS + + SAE EP+
Sbjct: 817 GTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPS 876
Query: 804 VAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNETS 863
AP+ V A S+S SEI V+W I K S G G+EV YW +E+++ +K GNE+
Sbjct: 877 AAPTDVKATSVSVSEILVAWKHI--KESLGRPQGFEVGYWKDMEQEDTAETVKTRGNESF 934
Query: 864 ARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNW 923
L GL+ N Y+ VRAYN AG GP S+ V+ TTKK+PPSQ P N+ W ++V L W
Sbjct: 935 VILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRWEQQGSQVSLGW 994
Query: 924 EQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELVLPIKEDYIIEVKATTDGGDG 983
E V + NESEV GYKVFYR +N QV+ T K A + LP YIIEV+A ++GGDG
Sbjct: 995 EPVIPLANESEVVGYKVFYRQEGHSNSQVIETQKLQAVVPLPDAGVYIIEVRAYSEGGDG 1054
Query: 984 TSSEQIRIPRITSMDARGSTSAISNVHPMSSYMPIVLFLIVYVL 1027
T+S QIR+P S TSA S +H +S+ V L+ ++
Sbjct: 1055 TASSQIRVP---SYSGGKITSAQSTLHSLSTSSSSVTLLLALMI 1095
>gi|28373126 contactin 4 isoform c precursor [Homo sapiens]
Length = 698
Score = 921 bits (2381), Expect = 0.0
Identities = 433/693 (62%), Positives = 560/693 (80%), Gaps = 2/693 (0%)
Query: 331 VEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIENGALTISNLSVTDSGMFQCIAEN 390
+E++++WEC+A+G+PKP+Y+WLKNG L+ +R QIE G L I+ ++++D+GM+QC+AEN
Sbjct: 1 MEENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAEN 60
Query: 391 KHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWKKGDVSV 450
KHG+++S+AEL V+A PDFS+ +K++ V+VG V ++CKP+ASP+ + +WKKG +
Sbjct: 61 KHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDIL 120
Query: 451 QEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMD 510
+E+ERI++ DG L+I NVTK+DAG+YTC+A N FG A+ T +LVV +PTR+ + PS+MD
Sbjct: 121 KENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMD 180
Query: 511 VSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGS-SSGDLMIRNIQL 569
V+VGES++LPCQV HD LDI+FTW FNG L DF +DG HFE+VGG S+GDLMIRNIQL
Sbjct: 181 VTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQL 240
Query: 570 KHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVI 629
KH+GKYVCMVQT VD +S+AADLIVRG PGPPE V +DEITDTTAQLSW+ G DNHSP+
Sbjct: 241 KHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPIT 300
Query: 630 SYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLP 689
Y IQARTPFSVGWQ V+TVPE+IDGKT TATVV LNPWVEYEFR VA+N IG GEPS P
Sbjct: 301 MYVIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRP 360
Query: 690 SEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGVTTWI 749
SEK RTEEA+PEV P+ V+GGGGS+SELVITW+ VPEELQNG GFGYVVAFRP G W+
Sbjct: 361 SEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYGKMIWM 420
Query: 750 QTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQV 809
TV+ S D RYVFRNES+ P+SP+EVKVGV+NNKGEGPFSP T V+SAEEEPT P+ +
Sbjct: 421 LTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASI 480
Query: 810 SANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNETSARLRGL 869
A SLS+++IEV W + P + + G + GYEV+YW KEE++ K++ GN+TS ++ L
Sbjct: 481 FARSLSATDIEVFWAS-PLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNL 539
Query: 870 KSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAM 929
K ++ Y+ AV+AYNSAG GP SATVNVTT+K PPSQPPGN++WN++D+K++LNW+QVKA+
Sbjct: 540 KGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKAL 599
Query: 930 ENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELVLPIKEDYIIEVKATTDGGDGTSSEQI 989
+NESEV GYKV YR + Q++ V+ TNKTS EL LP EDYIIE+K +DGGDG+SSEQI
Sbjct: 600 DNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQI 659
Query: 990 RIPRITSMDARGSTSAISNVHPMSSYMPIVLFL 1022
RIP+I++ ARGS ++ SN +S+ I++ L
Sbjct: 660 RIPKISNAYARGSGASTSNACTLSAISTIMISL 692
Score = 129 bits (323), Expect = 2e-29
Identities = 165/691 (23%), Positives = 271/691 (39%), Gaps = 79/691 (11%)
Query: 248 ECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNV 307
EC A G P P W ++ G P ++ +++ G L I DAG Y+C+AEN G
Sbjct: 8 ECKANGRPKPTYKWLKN-GEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIF 66
Query: 308 ARGRLTYYA-KPHWVQ-LIKDVE-IAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERT 364
+ L+ A P + + L+K V + V + EC+ PKP Y W K L ER
Sbjct: 67 SNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKENERI 126
Query: 365 QI-ENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLV---- 419
I E+G L I N++ +D+G + CIA N G S+ L V K+P + +V
Sbjct: 127 TISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVV--------KDPTRVMVPPSS 178
Query: 420 -QVQVGSLVSLDCKPR--ASPRALSSWKKG------DVSVQEHERISLLNDGG-LKIANV 469
V VG + L C+ S + +W D ER+ + G L I N+
Sbjct: 179 MDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNI 238
Query: 470 TKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDV--SVGESVILPCQVQHDP 527
AG Y CM + + + L+V P A + ++ + + P H P
Sbjct: 239 QLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSP 298
Query: 528 LLDIIFTWYFNGALADFKKDGSHFEKV-----GGSSSGDLMIRNIQLKHSGKYVCMVQTG 582
+ T Y A F V G + + ++ N +++ + V G
Sbjct: 299 I-----TMYVIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIG 353
Query: 583 VDSVSSAADLIVRGSPGP---PENVKVDEITDTTAQLSWKEGKD--NHSPVISYSIQART 637
+ S ++ P P NV + + ++W+ + + Y + R
Sbjct: 354 IGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRP 413
Query: 638 PFSVGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEE 697
+ W + TV D + ++P+ +E +V N G G P P+ V + E
Sbjct: 414 YGKMIW--MLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEG-PFSPTTVVYSAE 470
Query: 698 AVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGVTTW--------- 748
P PP+ + S +++ + W P E G GY V + W
Sbjct: 471 EEPTKPPASIFARSLSATDIEVFW-ASPLEKNRGRIQGYEVKY-------WRHEDKEENA 522
Query: 749 --IQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAP 806
I+TV T + + Y + V YN+ G GP S V + + P+ P
Sbjct: 523 RKIRTVGNQTSTKITNLKGSVL-----YHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPP 577
Query: 807 SQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRY-WNGGGKEESSSKMKVAGNETSAR 865
+ NS S S+I ++W+ + + + GY+V Y WN SS + N+TS
Sbjct: 578 GNIIWNS-SDSKIILNWDQVKALDNESEVKGYKVLYRWN-----RQSSTSVIETNKTSVE 631
Query: 866 LRGLKSNLAYYTAVRAYNSAGAGPFSATVNV 896
L L + Y ++ ++ G G S + +
Sbjct: 632 L-SLPFDEDYIIEIKPFSDGGDGSSSEQIRI 661
Score = 77.0 bits (188), Expect = 8e-14
Identities = 70/271 (25%), Positives = 116/271 (42%), Gaps = 30/271 (11%)
Query: 43 DKKITLHCEARGNPSPHYRWQLNGSDIDMSMEHRYKLNGGNLVVINPNRNWDTGTYQCFA 102
++ + C+A G P P Y+W NG + + + N+ ++N + D G YQC A
Sbjct: 2 EENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLS---DAGMYQCLA 58
Query: 103 TNSLGTIVSREAKLQFAYLENF-KTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNE 161
N G I S A +F +T ++ V+ G VV+ C P S + Y W +
Sbjct: 59 ENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKA-SPKPVYTW---K 114
Query: 162 YPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGV 221
+ +++ R E G+L I V SD G+YTC+ T+ A G+ LV++
Sbjct: 115 KGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGN---LVVK---- 167
Query: 222 MGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRS----------DGLPFSS 271
+P + P ++ G ++ L C + I + S DG F
Sbjct: 168 ----DPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHF-E 222
Query: 272 KIKLRKFSGVLEIPNFQQEDAGSYECIAENS 302
++ + +G L I N Q + AG Y C+ + S
Sbjct: 223 RVGGQDSAGDLMIRNIQLKHAGKYVCMVQTS 253
Score = 62.4 bits (150), Expect = 2e-09
Identities = 53/193 (27%), Positives = 82/193 (42%), Gaps = 25/193 (12%)
Query: 35 SIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDIDMSMEHRYKLNGGNLVVINPNRNWD 94
++ VG E + + C+ + +P P Y W+ G DI E GNL +IN ++ D
Sbjct: 89 TLVKVGGE---VVIECKPKASPKPVYTWK-KGRDILKENERITISEDGNLRIINVTKS-D 143
Query: 95 TGTYQCFATNSLGTIVSREAKLQFAYLENFKTKMR-----STVSVREGQGVVLLCGPP-P 148
G+Y C ATN GT S + K R S++ V G+ +VL C
Sbjct: 144 AGSYTCIATNHFGTASSTGNLV-------VKDPTRVMVPPSSMDVTVGESIVLPCQVTHD 196
Query: 149 HSGELSYAWIFNEYPSFVEEDSRRFV----SQETGHLYISKVEPSDVGNYTCVVTSMVTN 204
HS ++ + W FN + + D F G L I ++ G Y C+V + V
Sbjct: 197 HSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDR 256
Query: 205 ARVLGSPTPLVLR 217
L + L++R
Sbjct: 257 ---LSAAADLIVR 266
>gi|4827022 contactin 2 precursor [Homo sapiens]
Length = 1040
Score = 899 bits (2323), Expect = 0.0
Identities = 439/969 (45%), Positives = 616/969 (63%), Gaps = 13/969 (1%)
Query: 25 GPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDIDMSMEHRYKLNGGNL 84
GPVF +P + +FP S ++++ L C AR +P YRW++NG+++ + R++L GGNL
Sbjct: 36 GPVFEDQPLSVLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNL 95
Query: 85 VVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLC 144
V++NP + D G YQC A+N +GT+VSREA L+F +L+ F + R V EG GV+L C
Sbjct: 96 VIMNPTKAQDAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPC 155
Query: 145 GPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVVTSMV-- 202
PP H LSY W+ NE+P+F+ D R FVSQ TG+LYI++ SD+GNY+C+ TS +
Sbjct: 156 NPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDF 215
Query: 203 TNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWR 262
+ V L L ++ + P I+ +FP A G V LECFA GNP+P+I WR
Sbjct: 216 STKSVFSKFAQLNLAAEDTR-LFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWR 274
Query: 263 RSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQ 322
+ DG S + L+IP+ ED G+YEC AENS+G++ +GR+ A+P W++
Sbjct: 275 KVDG---SLSPQWTTAEPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPEWLK 331
Query: 323 LIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIENGALTISNLSVTDSG 382
+I D E + +L W C A+GKP+P+ RWL+NG L + R ++ G L S LS+ DSG
Sbjct: 332 VISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGDLRFSKLSLEDSG 391
Query: 383 MFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSS 442
M+QC+AENKHG +Y+SAEL V A APDF NP+++L+ G + + C+PRA+P+A+
Sbjct: 392 MYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVL 451
Query: 443 WKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRI 502
W KG + R+++ DG L I N++++D G YTC AEN GKAN T L V + T+I
Sbjct: 452 WSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTGILSVRDATKI 511
Query: 503 TLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSS-GD 561
TLAPS+ D+++G+++ L C HDP +D+ FTW + DF K G H+ + + GD
Sbjct: 512 TLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIGD 571
Query: 562 LMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEG 621
L I N QL+H GKY CM QT VDS S A ++VRG PGPP V V +I DTT QLSW G
Sbjct: 572 LTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGVVVRDIGDTTIQLSWSRG 631
Query: 622 KDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKI 681
DNHSP+ Y++QARTP + W+ V T P I+G TA V+ L PW++YEFRV+ASN +
Sbjct: 632 FDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEGNAETAQVLGLTPWMDYEFRVIASNIL 691
Query: 682 GGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFR 741
G GEPS PS K+RT EA P V PS ++GGGG+ EL++ W P+ E QNG+GFGY+++FR
Sbjct: 692 GTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELIVNWTPMSREYQNGDGFGYLLSFR 751
Query: 742 PLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEE 801
G T W V D +V+ NES+ PY+P+EVK+ YN +G+GP S V+SAEEE
Sbjct: 752 RQGSTHWQTARVPGADAQYFVYSNESVRPYTPFEVKIRSYNRRGDGPESLTALVYSAEEE 811
Query: 802 PTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNE 861
P VAP++V A +SSSE+ V+W + + NG LLGYE+RYW G KE ++ +++ AG +
Sbjct: 812 PRVAPTKVWAKGVSSSEMNVTWEPVQQDM-NGILLGYEIRYWKAGDKEAAADRVRTAGLD 870
Query: 862 TSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLL 921
TSAR+ GL N Y+ VRAYN AG GP S + N TT K PP +PPGN+ W + + + +
Sbjct: 871 TSARVSGLHPNTKYHVTVRAYNRAGTGPASPSANATTMKPPPRRPPGNISWTFSSSSLSI 930
Query: 922 NWEQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELVLPIKEDY---IIEVKATT 978
W+ V NES VTGYK+ Y+ + T K E +P+ ED +++++ T
Sbjct: 931 KWDPVVPFRNESAVTGYKMLYQNDLHLTPTLHLTGKNWIE--IPVPEDIGHALVQIRTTG 988
Query: 979 DGGDGTSSE 987
GGDG +E
Sbjct: 989 PGGDGIPAE 997
>gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens]
Length = 1007
Score = 877 bits (2266), Expect = 0.0
Identities = 439/984 (44%), Positives = 620/984 (63%), Gaps = 19/984 (1%)
Query: 8 LILLSFIGCLG--GELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLN 65
L+++S CL E GP+F ++P N+I+P S + K++L+C AR +P P Y+W++N
Sbjct: 10 LVIISITTCLAVSEEDKGFGPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMN 69
Query: 66 GSDIDMSMEHRYKLNGGNLVVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAYLENFK 125
D+D++ + RY + GGNLV+ NP++ D G Y C A+N+ G + S EA L F YL+ F
Sbjct: 70 NGDVDLTSD-RYSMVGGNLVINNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFP 128
Query: 126 TKMRSTVSVREGQGVVLLCGPPPH-SGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYIS 184
+ R V V+EG+G+VLLC PP H +LSY W+ NE+P F+ D RRFVSQ G+LYI+
Sbjct: 129 PEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIA 188
Query: 185 KVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGST 244
VE SD GNY+C V+S V PL+ + Y I VQF + A G
Sbjct: 189 NVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVY-ALMGQN 247
Query: 245 VKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRG 304
V LECFALGNP+P I WR+ P S ++ VL+I N Q ED G YEC AEN RG
Sbjct: 248 VTLECFALGNPVPDIRWRKVLE-PMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRG 306
Query: 305 KNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERT 364
K+ + R+ A P WV+ I D E+ + LYW C A+GKP P+ RWLKNG A
Sbjct: 307 KDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAY------ 360
Query: 365 QIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVG 424
G L + +++ ++GM+QCIAEN +G +Y++AELK++A AP F NPMKK + G
Sbjct: 361 --HKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKG 418
Query: 425 SLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQ 484
V ++CKP+A+P+ SW KG + RI + DG L+I N+T+ D G YTC AEN
Sbjct: 419 GRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENN 478
Query: 485 FGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADF 544
GKAN T LV+T+PTRI LAP N D++VGE+ + C DP LD+ F W FNG + DF
Sbjct: 479 RGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDF 538
Query: 545 KKDGSHFEK-VGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPEN 603
K+ H+++ S+G+L+IRN QLKH+G+Y C QT VD+ S++ADL+VRG PGPP
Sbjct: 539 NKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGG 598
Query: 604 VKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVV 663
+++++I T+ L+W G DNHSP+ Y+IQ +T S W+ T P +I+G A V
Sbjct: 599 LRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAV 658
Query: 664 ELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDP 723
+L PW+EYEFRVVA+N +G GEPS+PS +++T+ A P V PS+V GGGG EL ITW P
Sbjct: 659 DLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAP 718
Query: 724 VPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNN 783
+ E G FGY+VAF+P W + VT+PDT RYV ++E++ P + ++VKV +NN
Sbjct: 719 LSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNN 778
Query: 784 KGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYW 843
KG+GP+S V + SA++ P+ AP++V LSSSEI V W + K+ + Y++RYW
Sbjct: 779 KGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKI----VESYQIRYW 834
Query: 844 NGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPP 903
KEE++++++V E SARL L + Y+ V A NSAG GP S + TKK PP
Sbjct: 835 AAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPP 894
Query: 904 SQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELV 963
SQPP + + ++ ++ W+ V A+ NES VTGYKV YR Q++ ++ +T+K S E+
Sbjct: 895 SQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHKHSIEVP 954
Query: 964 LPIKEDYIIEVKATTDGGDGTSSE 987
+P +Y++EV+A +DGGDG S+
Sbjct: 955 IPRDGEYVVEVRAHSDGGDGVVSQ 978
Score = 76.3 bits (186), Expect = 1e-13
Identities = 73/285 (25%), Positives = 126/285 (44%), Gaps = 30/285 (10%)
Query: 764 RNESIVPYSPYEVKVGVYNNKGEG-PFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVS 822
R ++P+ YE +V N G G P P + + P VAPS V + E+ ++
Sbjct: 656 RAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTIT 715
Query: 823 WNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNETSARLRG---LKSNLAYYTAV 879
W + + G+ GY V + G+E K+ V +T + + + A+ V
Sbjct: 716 WAPLSREYHYGNNFGYIVAFKPFDGEEWK--KVTVTNPDTGRYVHKDETMSPSTAFQVKV 773
Query: 880 RAYNSAGAGPFSATVNVTTKKTPPSQPPGNV-VWNATDTKVLLNWEQVKAMENESEVTGY 938
+A+N+ G GP+S + + + PS+ P V V + +++ ++WE V E V Y
Sbjct: 774 KAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVL----EKIVESY 829
Query: 939 KVFY-----RTSSQNNVQVLNTNKTSA-ELVLPIKEDYIIEVKATTDGGDGTSSEQIRI- 991
++ Y + + N VQV + ++ E +LP + Y IEV A G G S+ I
Sbjct: 830 QIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQ-YFIEVGACNSAGCGPPSDMIEAF 888
Query: 992 ---------PRITSMDARGSTSAIS--NVHPMSSYMPIVLFLIVY 1025
PRI S GS I+ +V +S+ + + ++Y
Sbjct: 889 TKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLY 933
>gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]
Length = 1018
Score = 876 bits (2264), Expect = 0.0
Identities = 434/965 (44%), Positives = 612/965 (63%), Gaps = 17/965 (1%)
Query: 25 GPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDIDMSMEHRYKLNGGNL 84
GP+F ++P N+I+P S + K++L+C AR +P P Y+W++N D+D++ + RY + GGNL
Sbjct: 40 GPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSD-RYSMVGGNL 98
Query: 85 VVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLC 144
V+ NP++ D G Y C A+N+ G + S EA L F YL+ F + R V V+EG+G+VLLC
Sbjct: 99 VINNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLC 158
Query: 145 GPPPH-SGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVVTSMVT 203
PP H +LSY W+ NE+P F+ D RRFVSQ G+LYI+ VE SD GNY+C V+S
Sbjct: 159 DPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSI 218
Query: 204 NARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRR 263
V PL+ + Y I VQF + A G V LECFALGNP+P I WR+
Sbjct: 219 TKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVY-ALMGQNVTLECFALGNPVPDIRWRK 277
Query: 264 SDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQL 323
P S ++ VL+I N Q ED G YEC AEN RGK+ + R+ A P WV+
Sbjct: 278 VLE-PMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEH 336
Query: 324 IKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIENGALTISNLSVTDSGM 383
I D E+ + LYW C A+GKP P+ RWLKNG A G L + +++ ++GM
Sbjct: 337 INDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAY--------HKGELRLYDVTFENAGM 388
Query: 384 FQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSW 443
+QCIAEN +G +Y++AELK++A AP F NPMKK + G V ++CKP+A+P+ SW
Sbjct: 389 YQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSW 448
Query: 444 KKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRIT 503
KG + RI + DG L+I N+T+ D G YTC AEN GKAN T LV+T+PTRI
Sbjct: 449 SKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRII 508
Query: 504 LAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEK-VGGSSSGDL 562
LAP N D++VGE+ + C DP LD+ F W FNG + DF K+ H+++ S+G+L
Sbjct: 509 LAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGEL 568
Query: 563 MIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGK 622
+IRN QLKH+G+Y C QT VD+ S++ADL+VRG PGPP +++++I T+ L+W G
Sbjct: 569 LIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALTWSRGS 628
Query: 623 DNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIG 682
DNHSP+ Y+IQ +T S W+ T P +I+G A V+L PW+EYEFRVVA+N +G
Sbjct: 629 DNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLG 688
Query: 683 GGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRP 742
GEPS+PS +++T+ A P V PS+V GGGG EL ITW P+ E G FGY+VAF+P
Sbjct: 689 RGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKP 748
Query: 743 LGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEP 802
W + VT+PDT RYV ++E++ P + ++VKV +NNKG+GP+S V + SA++ P
Sbjct: 749 FDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAP 808
Query: 803 TVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNET 862
+ AP++V LSSSEI V W + K+ + Y++RYW KEE++++++V E
Sbjct: 809 SEAPTEVGVKVLSSSEISVHWEHVLEKI----VESYQIRYWAAHDKEEAANRVQVTSQEY 864
Query: 863 SARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLN 922
SARL L + Y+ V A NSAG GP S + TKK PPSQPP + + ++ ++
Sbjct: 865 SARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIIT 924
Query: 923 WEQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELVLPIKEDYIIEVKATTDGGD 982
W+ V A+ NES VTGYKV YR Q++ ++ +T+K S E+ +P +Y++EV+A +DGGD
Sbjct: 925 WDHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDGGD 984
Query: 983 GTSSE 987
G S+
Sbjct: 985 GVVSQ 989
Score = 76.3 bits (186), Expect = 1e-13
Identities = 73/285 (25%), Positives = 126/285 (44%), Gaps = 30/285 (10%)
Query: 764 RNESIVPYSPYEVKVGVYNNKGEG-PFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVS 822
R ++P+ YE +V N G G P P + + P VAPS V + E+ ++
Sbjct: 667 RAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTIT 726
Query: 823 WNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNETSARLRG---LKSNLAYYTAV 879
W + + G+ GY V + G+E K+ V +T + + + A+ V
Sbjct: 727 WAPLSREYHYGNNFGYIVAFKPFDGEEWK--KVTVTNPDTGRYVHKDETMSPSTAFQVKV 784
Query: 880 RAYNSAGAGPFSATVNVTTKKTPPSQPPGNV-VWNATDTKVLLNWEQVKAMENESEVTGY 938
+A+N+ G GP+S + + + PS+ P V V + +++ ++WE V E V Y
Sbjct: 785 KAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVL----EKIVESY 840
Query: 939 KVFY-----RTSSQNNVQVLNTNKTSA-ELVLPIKEDYIIEVKATTDGGDGTSSEQIRI- 991
++ Y + + N VQV + ++ E +LP + Y IEV A G G S+ I
Sbjct: 841 QIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQ-YFIEVGACNSAGCGPPSDMIEAF 899
Query: 992 ---------PRITSMDARGSTSAIS--NVHPMSSYMPIVLFLIVY 1025
PRI S GS I+ +V +S+ + + ++Y
Sbjct: 900 TKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLY 944
>gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo
sapiens]
Length = 1248
Score = 409 bits (1052), Expect = e-114
Identities = 297/1003 (29%), Positives = 463/1003 (46%), Gaps = 68/1003 (6%)
Query: 20 ELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDI----DMSMEH 75
E L++ PV ++ + ++D I+L CEA G P +RW +G ++ +
Sbjct: 24 EELMEPPVITEQSPRRLVVFPTDD--ISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTV 81
Query: 76 RYKLNGGNLVVINPNRNWDT---GTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTV 132
+ G+ + N N+ G Y+CFA+N LGT +S E +L + + V
Sbjct: 82 YQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPV 141
Query: 133 SVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDV- 191
V EG+ VVL C PPP + L W+ N +++D R + Q G+LY + V SD
Sbjct: 142 EVEEGESVVLPCNPPPSAEPLRIYWM-NSKILHIKQDERVTMGQN-GNLYFANVLTSDNH 199
Query: 192 GNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPET----LPAAKGSTVKL 247
+Y C T + P L +++ M + +P++ FP L A +G + L
Sbjct: 200 SDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL--LFPTNSSSHLVALQGQPLVL 257
Query: 248 ECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNV 307
EC A G P P I W R G + ++ + + L++ +ED G Y C+AENS G
Sbjct: 258 ECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSAR 317
Query: 308 ARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAA---LVLEERT 364
+T A P+W+ + ++ +C+ G+P+P W NG L +++
Sbjct: 318 HAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY 377
Query: 365 QIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVG 424
+I+ GAL +SN+ +D+ + QC A N+HGL+ ++A + VV + + VQ G
Sbjct: 378 RIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQ-G 436
Query: 425 SLVSLDCKPRASPRALSSWKKGD-VSVQEHERISLLNDGGLKIANVTKADAGTYTCMAEN 483
S L CK +P W D +V + ER +G L I ++ D G Y C+A N
Sbjct: 437 STAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 496
Query: 484 QFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALAD 543
+L V + T+IT P + G V CQ DP L TW
Sbjct: 497 DQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-------- 548
Query: 544 FKKDGSHFEKVGGSSS-----GDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSP 598
+ DG +++G S G L+I ++ G Y C+ T +D V S A L+V GSP
Sbjct: 549 -RGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 607
Query: 599 GPPENVKVDEI---TDTTAQLSWKEGKDNHSPVISYSIQARTPFSVG--WQTVTTVPEVI 653
GP + + ++ T + ++SW +D+++P+ Y I+ W ++ VP
Sbjct: 608 GPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPG-- 665
Query: 654 DGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGS 713
T+T ++L+P+V Y FRV A NK G GEPS SE V T EA PE P +V G G
Sbjct: 666 ---NQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNE 722
Query: 714 RSELVITWDPVPEELQNGEGFGYVVAFRPLGVT-TWIQTVVTSPDTPRYVFRNESIVPYS 772
+ +VITW P+ N Y V +RP G W + +V+ P V N S +
Sbjct: 723 TTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSD---PFLVVSNTS--TFV 777
Query: 773 PYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSN 832
PYE+KV N++G+GP VT +S E+ P P L+SS + V W +
Sbjct: 778 PYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVK 837
Query: 833 GHLLGYEVRYWNGGGKEESSSK------MKVAGNETSARLRGLKSNLAYYTAVRAYNSAG 886
GHL GY V YW G + + S + + V N TS L GL+ +Y+ V+A+N G
Sbjct: 838 GHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRG 897
Query: 887 AGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSS 946
+GP ++ +T + P P + ++T +LL W+ + + +TGY + Y
Sbjct: 898 SGP-ASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLSYHPLD 954
Query: 947 QNNVQVLNTNKTSAELVLPIKED------YIIEVKATTDGGDG 983
+ L+ N EL D Y +++ATT G G
Sbjct: 955 EGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPG 997
Score = 38.9 bits (89), Expect = 0.025
Identities = 42/187 (22%), Positives = 84/187 (44%), Gaps = 20/187 (10%)
Query: 596 GSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDG 655
G PG PE + ++ ++T+ L W+ +H+ V++ + + P G + + + D
Sbjct: 911 GVPGHPEALHLECQSNTSLLLRWQPPL-SHNGVLTGYVLSYHPLDEGGKGQLSF-NLRDP 968
Query: 656 KTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRS 715
+ T + +L+P + Y F++ A+ K G GE + + + G +
Sbjct: 969 ELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAG---EN 1025
Query: 716 ELVITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNES------IV 769
V++W VP+E Q F + + F+ LG ++ +P+YV N+S +
Sbjct: 1026 YSVVSW--VPKEGQC--NFRFHILFKALGEEKGGASL-----SPQYVSYNQSSYTQWDLQ 1076
Query: 770 PYSPYEV 776
P + YE+
Sbjct: 1077 PDTDYEI 1083
>gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 1253
Score = 409 bits (1050), Expect = e-114
Identities = 296/1004 (29%), Positives = 463/1004 (46%), Gaps = 68/1004 (6%)
Query: 19 GELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDI----DMSME 74
G +++ PV ++ + ++D I+L CEA G P +RW +G ++ +
Sbjct: 28 GHHVMEPPVITEQSPRRLVVFPTDD--ISLKCEASGKPEVQFRWTRDGVHFKPKEELGVT 85
Query: 75 HRYKLNGGNLVVINPNRNWDT---GTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRST 131
+ G+ + N N+ G Y+CFA+N LGT +S E +L + +
Sbjct: 86 VYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKP 145
Query: 132 VSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDV 191
V V EG+ VVL C PPP + L W+ N +++D R + Q G+LY + V SD
Sbjct: 146 VEVEEGESVVLPCNPPPSAEPLRIYWM-NSKILHIKQDERVTMGQN-GNLYFANVLTSDN 203
Query: 192 -GNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPET----LPAAKGSTVK 246
+Y C T + P L +++ M + +P++ FP L A +G +
Sbjct: 204 HSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL--LFPTNSSSHLVALQGQPLV 261
Query: 247 LECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKN 306
LEC A G P P I W R G + ++ + + L++ +ED G Y C+AENS G
Sbjct: 262 LECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSA 321
Query: 307 VARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAA---LVLEER 363
+T A P+W+ + ++ +C+ G+P+P W NG L +++
Sbjct: 322 RHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQK 381
Query: 364 TQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQV 423
+I+ GAL +SN+ +D+ + QC A N+HGL+ ++A + VV + + VQ
Sbjct: 382 YRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQ- 440
Query: 424 GSLVSLDCKPRASPRALSSWKKGD-VSVQEHERISLLNDGGLKIANVTKADAGTYTCMAE 482
GS L CK +P W D +V + ER +G L I ++ D G Y C+A
Sbjct: 441 GSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAA 500
Query: 483 NQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALA 542
N +L V + T+IT P + G V CQ DP L TW
Sbjct: 501 NDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW------- 553
Query: 543 DFKKDGSHFEKVGGSSS-----GDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGS 597
+ DG +++G S G L+I ++ G Y C+ T +D V S A L+V GS
Sbjct: 554 --RGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGS 611
Query: 598 PGPPENVKVDEI---TDTTAQLSWKEGKDNHSPVISYSIQARTPFSVG--WQTVTTVPEV 652
PGP + + ++ T + ++SW +D+++P+ Y I+ W ++ VP
Sbjct: 612 PGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPG- 670
Query: 653 IDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGG 712
T+T ++L+P+V Y FRV A NK G GEPS SE V T EA PE P +V G G
Sbjct: 671 ----NQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGN 726
Query: 713 SRSELVITWDPVPEELQNGEGFGYVVAFRPLGVT-TWIQTVVTSPDTPRYVFRNESIVPY 771
+ +VITW P+ N Y V +RP G W + +V+ P V N S +
Sbjct: 727 ETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSD---PFLVVSNTS--TF 781
Query: 772 SPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLS 831
PYE+KV N++G+GP VT +S E+ P P L+SS + V W +
Sbjct: 782 VPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQV 841
Query: 832 NGHLLGYEVRYWNGGGKEESSSK------MKVAGNETSARLRGLKSNLAYYTAVRAYNSA 885
GHL GY V YW G + + S + + V N TS L GL+ +Y+ V+A+N
Sbjct: 842 KGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGR 901
Query: 886 GAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTS 945
G+GP ++ +T + P P + ++T +LL W+ + + +TGY + Y
Sbjct: 902 GSGP-ASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLSYHPL 958
Query: 946 SQNNVQVLNTNKTSAELVLPIKED------YIIEVKATTDGGDG 983
+ L+ N EL D Y +++ATT G G
Sbjct: 959 DEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPG 1002
Score = 38.9 bits (89), Expect = 0.025
Identities = 42/187 (22%), Positives = 84/187 (44%), Gaps = 20/187 (10%)
Query: 596 GSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDG 655
G PG PE + ++ ++T+ L W+ +H+ V++ + + P G + + + D
Sbjct: 916 GVPGHPEALHLECQSNTSLLLRWQPPL-SHNGVLTGYVLSYHPLDEGGKGQLSF-NLRDP 973
Query: 656 KTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRS 715
+ T + +L+P + Y F++ A+ K G GE + + + G +
Sbjct: 974 ELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAG---EN 1030
Query: 716 ELVITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNES------IV 769
V++W VP+E Q F + + F+ LG ++ +P+YV N+S +
Sbjct: 1031 YSVVSW--VPKEGQC--NFRFHILFKALGEEKGGASL-----SPQYVSYNQSSYTQWDLQ 1081
Query: 770 PYSPYEV 776
P + YE+
Sbjct: 1082 PDTDYEI 1088
>gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 1257
Score = 409 bits (1050), Expect = e-114
Identities = 296/1004 (29%), Positives = 463/1004 (46%), Gaps = 68/1004 (6%)
Query: 19 GELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDI----DMSME 74
G +++ PV ++ + ++D I+L CEA G P +RW +G ++ +
Sbjct: 28 GHHVMEPPVITEQSPRRLVVFPTDD--ISLKCEASGKPEVQFRWTRDGVHFKPKEELGVT 85
Query: 75 HRYKLNGGNLVVINPNRNWDT---GTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRST 131
+ G+ + N N+ G Y+CFA+N LGT +S E +L + +
Sbjct: 86 VYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKP 145
Query: 132 VSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDV 191
V V EG+ VVL C PPP + L W+ N +++D R + Q G+LY + V SD
Sbjct: 146 VEVEEGESVVLPCNPPPSAEPLRIYWM-NSKILHIKQDERVTMGQN-GNLYFANVLTSDN 203
Query: 192 -GNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPET----LPAAKGSTVK 246
+Y C T + P L +++ M + +P++ FP L A +G +
Sbjct: 204 HSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL--LFPTNSSSHLVALQGQPLV 261
Query: 247 LECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKN 306
LEC A G P P I W R G + ++ + + L++ +ED G Y C+AENS G
Sbjct: 262 LECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSA 321
Query: 307 VARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAA---LVLEER 363
+T A P+W+ + ++ +C+ G+P+P W NG L +++
Sbjct: 322 RHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQK 381
Query: 364 TQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQV 423
+I+ GAL +SN+ +D+ + QC A N+HGL+ ++A + VV + + VQ
Sbjct: 382 YRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQ- 440
Query: 424 GSLVSLDCKPRASPRALSSWKKGD-VSVQEHERISLLNDGGLKIANVTKADAGTYTCMAE 482
GS L CK +P W D +V + ER +G L I ++ D G Y C+A
Sbjct: 441 GSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAA 500
Query: 483 NQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALA 542
N +L V + T+IT P + G V CQ DP L TW
Sbjct: 501 NDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW------- 553
Query: 543 DFKKDGSHFEKVGGSSS-----GDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGS 597
+ DG +++G S G L+I ++ G Y C+ T +D V S A L+V GS
Sbjct: 554 --RGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGS 611
Query: 598 PGPPENVKVDEI---TDTTAQLSWKEGKDNHSPVISYSIQARTPFSVG--WQTVTTVPEV 652
PGP + + ++ T + ++SW +D+++P+ Y I+ W ++ VP
Sbjct: 612 PGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPG- 670
Query: 653 IDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGG 712
T+T ++L+P+V Y FRV A NK G GEPS SE V T EA PE P +V G G
Sbjct: 671 ----NQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGN 726
Query: 713 SRSELVITWDPVPEELQNGEGFGYVVAFRPLGVT-TWIQTVVTSPDTPRYVFRNESIVPY 771
+ +VITW P+ N Y V +RP G W + +V+ P V N S +
Sbjct: 727 ETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSD---PFLVVSNTS--TF 781
Query: 772 SPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLS 831
PYE+KV N++G+GP VT +S E+ P P L+SS + V W +
Sbjct: 782 VPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQV 841
Query: 832 NGHLLGYEVRYWNGGGKEESSSK------MKVAGNETSARLRGLKSNLAYYTAVRAYNSA 885
GHL GY V YW G + + S + + V N TS L GL+ +Y+ V+A+N
Sbjct: 842 KGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGR 901
Query: 886 GAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTS 945
G+GP ++ +T + P P + ++T +LL W+ + + +TGY + Y
Sbjct: 902 GSGP-ASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLSYHPL 958
Query: 946 SQNNVQVLNTNKTSAELVLPIKED------YIIEVKATTDGGDG 983
+ L+ N EL D Y +++ATT G G
Sbjct: 959 DEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPG 1002
Score = 38.9 bits (89), Expect = 0.025
Identities = 42/187 (22%), Positives = 84/187 (44%), Gaps = 20/187 (10%)
Query: 596 GSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDG 655
G PG PE + ++ ++T+ L W+ +H+ V++ + + P G + + + D
Sbjct: 916 GVPGHPEALHLECQSNTSLLLRWQPPL-SHNGVLTGYVLSYHPLDEGGKGQLSF-NLRDP 973
Query: 656 KTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRS 715
+ T + +L+P + Y F++ A+ K G GE + + + G +
Sbjct: 974 ELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAG---EN 1030
Query: 716 ELVITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNES------IV 769
V++W VP+E Q F + + F+ LG ++ +P+YV N+S +
Sbjct: 1031 YSVVSW--VPKEGQC--NFRFHILFKALGEEKGGASL-----SPQYVSYNQSSYTQWDLQ 1081
Query: 770 PYSPYEV 776
P + YE+
Sbjct: 1082 PDTDYEI 1088
>gi|27894376 cell adhesion molecule with homology to L1CAM precursor
[Homo sapiens]
Length = 1224
Score = 375 bits (962), Expect = e-103
Identities = 279/1015 (27%), Positives = 458/1015 (45%), Gaps = 84/1015 (8%)
Query: 24 QGPVFIKEPSNSI-FPVGSEDKKITLHCEARGNPSPHYRWQLNGSDIDMSMEHRY--KLN 80
Q P IK+ + FP D+ + CEA+GNP P + W +G+ + +HR N
Sbjct: 33 QVPTIIKQSKVQVAFPF---DEYFQIECEAKGNPEPTFSWTKDGNPFYFT-DHRIIPSNN 88
Query: 81 GGNLVVINPNR-NWDTGTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQG 139
G + N + G Y+CFA+N LG +S E + + F + + V EG
Sbjct: 89 SGTFRIPNEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDP 148
Query: 140 VVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTC--- 196
+VL C PP L W+ E +E+D R ++SQ+ G LY + VE D N C
Sbjct: 149 IVLPCNPPKGLPPLHIYWMNIEL-EHIEQDERVYMSQK-GDLYFANVEEKDSRNDYCCFA 206
Query: 197 ---------------VVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKI-----EVQFPET 236
+ + + +A S T + +++ + + +PK+ E +
Sbjct: 207 AFPRLRTIVQKMPMKLTVNSLKHANDSSSSTEIGSKANSIK-QRKPKLLLPPTESGSESS 265
Query: 237 LPAAKGSTVKLECFALGNPIPQINWRRSDG-LPFSSKIKLRKFSGVLEIPNFQQEDAGSY 295
+ KG + LECFA G P PQ++W + G LP + K + L+I N +D G+Y
Sbjct: 266 ITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGRETK-ENYGKTLKIENVSYQDKGNY 324
Query: 296 ECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNG 355
C A N G + P W + + + + C A G+P+P+ +W NG
Sbjct: 325 RCTASNFLGTATHDFHVIVEEPPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNG 384
Query: 356 AALVLEERTQ--IENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKN 413
+ + + ++ +NL + ++QC A N HG + ++A + VV P
Sbjct: 385 SPVDNHPFAGDVVFPREISFTNLQPNHTAVYQCEASNVHGTILANANIDVVDVRPLIQTK 444
Query: 414 PMKKLVQVQVGSLVSLDCKPRASPRALSSWKK-GDVSVQEHERISLLNDGGLKIANVTKA 472
+ V VG L C+ ASP A+ SW+K +V E R + +G L+I T+
Sbjct: 445 DGENYATV-VGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENGTLQINRTTEE 503
Query: 473 DAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDII 532
DAG+Y+C EN GK T +L + T++ ++P N + + L C+ + D L
Sbjct: 504 DAGSYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHCESKCDSHLK-- 561
Query: 533 FTWYFNGALADFKKDGSHFEKVGGSSSG-------DLMIRNIQLKHSGKYVCMVQTGVDS 585
+ + KDG FE + G+ G +L I N+ L+ G Y C T +DS
Sbjct: 562 -----HSLKLSWSKDGEAFE-INGTEDGRIIIDGANLTISNVTLEDQGIYCCSAHTALDS 615
Query: 586 VSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQ--ARTPFSVGW 643
+ + V P PPEN+ + E + + +L+W+ G D++S + Y ++ W
Sbjct: 616 AADITQVTVLDVPDPPENLHLSERQNRSVRLTWEAGADHNSNISEYIVEFEGNKEEPGRW 675
Query: 644 QTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVP 703
+ +T V GK T ++ L P+V Y+FRV+A N++G +PS PS+ T A P+
Sbjct: 676 EELTRV----QGKK-TTVILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRN 730
Query: 704 PSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGV-TTWIQTVVTSPDTPRYV 762
P + E++I W+P+ QNG G Y V ++P G W + VT+ +
Sbjct: 731 PQNIRVQASQPKEMIIKWEPLKSMEQNGPGLEYRVTWKPQGAPVEWEEETVTN-----HT 785
Query: 763 FRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVS 822
R + Y+PY+VKV N G GP T++S E+ P AP + ++S+ ++V+
Sbjct: 786 LRVMTPAVYAPYDVKVQAINQLGSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVT 845
Query: 823 WNTIPWKLSNGHLLGYEVRYW------NGGGKEESSSKMKVAGNETSARLRGLKSNLAYY 876
W+T+P +G L GY++ +W +G + + ++ +G S + L + ++
Sbjct: 846 WSTVPKDRVHGRLKGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDAFSEFH 905
Query: 877 TAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVT 936
V AYNS GAGP S T + P QP V L+W K + +T
Sbjct: 906 LTVLAYNSKGAGPESEPYIFQTPEGVPEQPTFLKVIKVDKDTATLSWGLPKKL--NGNLT 963
Query: 937 GYKVFYRTSSQ-------NNVQVLNTNKTSAELV-LPIKEDYIIEVKATTDGGDG 983
GY + Y+ + N++ + +K S L L Y ++A T G G
Sbjct: 964 GYLLQYQIINDTYEIGELNDINITTPSKPSWHLSNLNATTKYKFYLRACTSQGCG 1018
>gi|81158224 neuronal cell adhesion molecule isoform B precursor
[Homo sapiens]
Length = 1183
Score = 374 bits (960), Expect = e-103
Identities = 285/961 (29%), Positives = 425/961 (44%), Gaps = 68/961 (7%)
Query: 8 LILLSFIGCLGGELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGS 67
L L I L L L P I + S + + + I + CEA+G P P + W NG+
Sbjct: 21 LFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPREN-IVIQCEAKGKPPPSFSWTRNGT 79
Query: 68 --DIDMSMEHRYKLNGGNLVV-INPNRNWDT--GTYQCFATNSLGTIVSREAKLQFAYLE 122
DID K G L++ I +T G YQC A N G VS ++ +
Sbjct: 80 HFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSP 139
Query: 123 NFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLY 182
+ + ++++ GQ +VL C PP W+ N + + S R G LY
Sbjct: 140 LWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQ--SERVSQGLNGDLY 197
Query: 183 ISKVEPSDV-GNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGE-----------YEPKIE 230
S V P D +Y C T P + + S + + Y K
Sbjct: 198 FSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSS 257
Query: 231 VQFPETL----------PAAKGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSG 280
+ P T +G+ + LEC A G P P I W + DG+ ++ + F
Sbjct: 258 RERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEK 317
Query: 281 VLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECR 340
L+I + + D+G+Y+CIA+N+ G + A P+W+ +++ ++ + CR
Sbjct: 318 TLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICR 377
Query: 341 ASGKPKPSYRWLKNGAALVL---EERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYS 397
A+G PKP WL NG + + + +I+ + SN+ S ++QC A N++G + +
Sbjct: 378 ANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLA 437
Query: 398 SAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERIS 457
+A + V+A P P L QV LDC SP W KG HE I
Sbjct: 438 NAFVNVLAEPPRI-LTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIY 496
Query: 458 LLNDGG-LKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGES 516
+L++ G L+I K GTYTC+A N+ G A HL + +PT I P V G
Sbjct: 497 VLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSM 556
Query: 517 VILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYV 576
V C+V+HD L + W L D ++ S ++ L++ ++ SG Y
Sbjct: 557 VSFECKVKHDHTLSLTVLW-----LKDNRELPS--DERFTVDKDHLVVADVSDDDSGTYT 609
Query: 577 CMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQAR 636
C+ T +DSVS++A L V P PP ++++ + D + QLSW G DN+SP+ + I+
Sbjct: 610 CVANTTLDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYE 669
Query: 637 TPFSVG--WQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVR 694
W T V T T ++L+P+V Y FRV+A N IG PS SE+
Sbjct: 670 DAMHKPGLWHHQTEV-----SGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYL 724
Query: 695 TEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPL-GVTTWIQTVV 753
T+ + P+ P+ V G G LVITW P+ NG G Y V++R G W VV
Sbjct: 725 TKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVV 784
Query: 754 TSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANS 813
+ +Y+ + PY +KV N+ G P V S E+ P VAP V N
Sbjct: 785 A--NVSKYIV--SGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNV 840
Query: 814 LSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSK----------MKVAGNETS 863
++S+ EV W+ +P K GHL GY + YW K +SSSK + G++T
Sbjct: 841 VNSTLAEVHWDPVPLKSIRGHLQGYRIYYW----KTQSSSKRNRRHIEKKILTFQGSKTH 896
Query: 864 ARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNW 923
L GL+ Y VR N G GP S T + PS P + N T + L W
Sbjct: 897 GMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEW 956
Query: 924 E 924
+
Sbjct: 957 D 957
Score = 144 bits (364), Expect = 3e-34
Identities = 181/767 (23%), Positives = 310/767 (40%), Gaps = 103/767 (13%)
Query: 181 LYISKVEPSDVGNYTCVVTSMV------TNARVLGSPTPLVLRSDGVMGEYEPKIEVQFP 234
L I V +D GNY C+ + + + RV +P + P
Sbjct: 319 LQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAP-----------------YWITAP 361
Query: 235 ETLPAAKGSTVKLECFALGNPIPQINWRRSDGLPF--SSKIKLRKFSG-VLEIPNFQQED 291
+ L + G L C A GNP P+I+W ++G+P + RK G + N Q+
Sbjct: 362 QNLVLSPGEDGTLICRANGNPKPRISWL-TNGVPIEIAPDDPSRKIDGDTIIFSNVQERS 420
Query: 292 AGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDV--EIAVEDSLYWECRASGKPKPSY 349
+ Y+C A N G +A + A+P + + ++ +C G P P+
Sbjct: 421 SAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTI 480
Query: 350 RWLKNGAALVLEERTQI--ENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKV---- 403
W K L E + ENG L I +G + C+A NK G+ + L++
Sbjct: 481 EWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPT 540
Query: 404 -VASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSS--WKKGDVSVQEHERISLLN 460
+ P+++ VQ GS+VS +CK + + W K + + ER ++
Sbjct: 541 WIVKQPEYAV--------VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDK 592
Query: 461 DGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVS--VGESVI 518
D L +A+V+ D+GTYTC+A + + L V + + P +++++ + +SV
Sbjct: 593 DH-LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVD---VPNPPFDLELTDQLDKSVQ 648
Query: 519 L---PCQVQHDPLLDIIFTWYFNGALADFKKDG--SHFEKVGGSSSGDLMIRNIQLKHSG 573
L P + P+ I + A+ K G H +V G+ + + + + +S
Sbjct: 649 LSWTPGDDNNSPITKFIIE--YEDAM---HKPGLWHHQTEVSGTQTTAQLKLSPYVNYSF 703
Query: 574 KYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQ---LSWK--EGKDNHSPV 628
+ + + G S A++ + + P +N E + ++WK G +++ P
Sbjct: 704 RVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPG 763
Query: 629 ISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELNP-WVEYEFRVVASNKIG-GGEP 686
+ Y + R T V V + +V P +V Y +V A N +G EP
Sbjct: 764 LQYKVSWRQKDGDDEWTSVVVANV------SKYIVSGTPTFVPYLIKVQALNDMGFAPEP 817
Query: 687 SLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGVT 746
++ + E +P V P V + + + WDPVP + G GY + +
Sbjct: 818 AVVMG--HSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYY------ 869
Query: 747 TWIQTVVTSPDTPRYVFRN-------------ESIVPYSPYEVKVGVYNNKGEGPFSPVT 793
W +T +S R++ + + P+S Y + V V N KGEGP SP
Sbjct: 870 -W-KTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASP-D 926
Query: 794 TVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSS 853
VF+ E APS + + + + + W+ P NG L Y ++Y E
Sbjct: 927 RVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD--PPSHPNGILTEYTLKYQPINSTHELGP 984
Query: 854 --KMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTT 898
+K+ N+T L+ L + Y A SAG+G VTT
Sbjct: 985 LVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTT 1031
>gi|81158226 neuronal cell adhesion molecule isoform A precursor
[Homo sapiens]
Length = 1304
Score = 365 bits (936), Expect = e-100
Identities = 276/935 (29%), Positives = 413/935 (44%), Gaps = 77/935 (8%)
Query: 44 KKITLHCEARGNPSPHYRWQLNGS--DIDMSMEHRYKLNGGNLVV-INPNRNWDT--GTY 98
+ I + CEA+G P P + W NG+ DID K G L++ I +T G Y
Sbjct: 62 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 121
Query: 99 QCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWI 158
QC A N G VS ++ + + + ++++ GQ +VL C PP W+
Sbjct: 122 QCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWM 181
Query: 159 FNEYPSFVEEDSRRFVSQETGHLYISKVEPSDV-GNYTCVVTSMVTNARVLGSPTPLVLR 217
N + + S R G LY S V P D +Y C T P + +
Sbjct: 182 DNSFQRLPQ--SERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVI 239
Query: 218 SDGVMGE-----------YEPKIEVQFPETL----------PAAKGSTVKLECFALGNPI 256
S + + Y K + P T +G+ + LEC A G P
Sbjct: 240 SVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPT 299
Query: 257 PQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYA 316
P I W + DG+ ++ + F L+I + + D+G+Y+CIA+N+ G + A
Sbjct: 300 PIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKA 359
Query: 317 KPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVL---EERTQIENGALTI 373
P+W+ +++ ++ + CRA+G PKP WL NG + + + +I+ +
Sbjct: 360 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIF 419
Query: 374 SNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKP 433
SN+ S ++QC A N++G + ++A + V+A P P L QV LDC
Sbjct: 420 SNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI-LTPANTLYQVIANRPALLDCAF 478
Query: 434 RASPRALSSWKKGDVSVQEHERISLLNDGG-LKIANVTKADAGTYTCMAENQFGKANGTT 492
SP W KG HE I +L++ G L+I K GTYTC+A N+ G A
Sbjct: 479 FGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEV 538
Query: 493 HLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFE 552
HL + +PT I P V G V C+V+HD L + W L D ++ S +
Sbjct: 539 HLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW-----LKDNRELPS--D 591
Query: 553 KVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGS----------PGPPE 602
+ L++ ++ SG Y C+ T +DSVS++A L V P PP
Sbjct: 592 ERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPF 651
Query: 603 NVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVG--WQTVTTVPEVIDGKTHTA 660
++++ + D + QLSW G DN+SP+ + I+ W T V T T
Sbjct: 652 DLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEV-----SGTQTT 706
Query: 661 TVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVIT 720
++L+P+V Y FRV+A N IG PS SE+ T+ + P+ P+ V G G LVIT
Sbjct: 707 AQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVIT 766
Query: 721 WDPVPEELQNGEGFGYVVAFRPL-GVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVG 779
W P+ NG G Y V++R G W VV + +Y+ + PY +KV
Sbjct: 767 WKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVA--NVSKYIV--SGTPTFVPYLIKVQ 822
Query: 780 VYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYE 839
N+ G P V S E+ P VAP V N ++S+ EV W+ +P K GHL GY
Sbjct: 823 ALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYR 882
Query: 840 VRYWNGGGKEESSSK----------MKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGP 889
+ YW K +SSSK + G++T L GL+ Y VR N G GP
Sbjct: 883 IYYW----KTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGP 938
Query: 890 FSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWE 924
S T + PS P + N T + L W+
Sbjct: 939 ASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD 973
Score = 147 bits (372), Expect = 4e-35
Identities = 190/814 (23%), Positives = 322/814 (39%), Gaps = 121/814 (14%)
Query: 181 LYISKVEPSDVGNYTCVVTSMV------TNARVLGSPTPLVLRSDGVMGEYEPKIEVQFP 234
L I V +D GNY C+ + + + RV +P + P
Sbjct: 325 LQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAP-----------------YWITAP 367
Query: 235 ETLPAAKGSTVKLECFALGNPIPQINWRRSDGLPF--SSKIKLRKFSG-VLEIPNFQQED 291
+ L + G L C A GNP P+I+W ++G+P + RK G + N Q+
Sbjct: 368 QNLVLSPGEDGTLICRANGNPKPRISWL-TNGVPIEIAPDDPSRKIDGDTIIFSNVQERS 426
Query: 292 AGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDV--EIAVEDSLYWECRASGKPKPSY 349
+ Y+C A N G +A + A+P + + ++ +C G P P+
Sbjct: 427 SAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTI 486
Query: 350 RWLKNGAALVLEERTQI--ENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKV---- 403
W K L E + ENG L I +G + C+A NK G+ + L++
Sbjct: 487 EWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPT 546
Query: 404 -VASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSS--WKKGDVSVQEHERISLLN 460
+ P+++ VQ GS+VS +CK + + W K + + ER ++
Sbjct: 547 WIVKQPEYAV--------VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDK 598
Query: 461 DGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTR-------ITLAPSNMDVS- 512
D L +A+V+ D+GTYTC+A + + L V PT + P +++++
Sbjct: 599 DH-LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTD 657
Query: 513 -VGESVIL---PCQVQHDPLLDIIFTWYFNGALADFKKDG--SHFEKVGGSSSGDLMIRN 566
+ +SV L P + P+ I + A+ K G H +V G+ + + +
Sbjct: 658 QLDKSVQLSWTPGDDNNSPITKFIIE--YEDAM---HKPGLWHHQTEVSGTQTTAQLKLS 712
Query: 567 IQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQ---LSWK--EG 621
+ +S + + + G S A++ + + P +N E + ++WK G
Sbjct: 713 PYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNG 772
Query: 622 KDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELNP-WVEYEFRVVASNK 680
+++ P + Y + R T V V + +V P +V Y +V A N
Sbjct: 773 FESNGPGLQYKVSWRQKDGDDEWTSVVVANV------SKYIVSGTPTFVPYLIKVQALND 826
Query: 681 IG-GGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVA 739
+G EP++ + E +P V P V + + + WDPVP + G GY +
Sbjct: 827 MGFAPEPAVVMG--HSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIY 884
Query: 740 FRPLGVTTWIQTVVTSPDTPRYVFRN-------------ESIVPYSPYEVKVGVYNNKGE 786
+ W +T +S R++ + + P+S Y + V V N KGE
Sbjct: 885 Y-------W-KTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGE 936
Query: 787 GPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGG 846
GP SP VF+ E APS + + + + + W+ P NG L Y ++Y
Sbjct: 937 GPASP-DRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD--PPSHPNGILTEYTLKYQPIN 993
Query: 847 GKEESSS--KMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPS 904
E +K+ N+T L+ L + Y A SAG+G VTT
Sbjct: 994 STHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGI 1053
Query: 905 QPP--------------GNVVWNATDTKVLLNWE 924
PP N+ A +T ++WE
Sbjct: 1054 LPPDVGAGKVQAVNPRISNLTAAAAETYANISWE 1087
Score = 116 bits (291), Expect = 9e-26
Identities = 211/934 (22%), Positives = 349/934 (37%), Gaps = 131/934 (14%)
Query: 26 PVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDIDMSMEHR--YKLNGGN 83
P F+ N+ ++L C A G P+P W + M ++R YK
Sbjct: 268 PTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYW---AKEDGMLPKNRTVYKNFEKT 324
Query: 84 LVVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLL 143
L +I+ + D+G YQC A N+LG I ++ + T ++ V + G+ L+
Sbjct: 325 LQIIHVSEA-DSGNYQCIAKNALGAI-HHTISVRVKAAPYWITAPQNLV-LSPGEDGTLI 381
Query: 144 C----GPPPHSGELSYAWIFNEYP-SFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVV 198
C P P +W+ N P +D R + +T + S V+ Y C
Sbjct: 382 CRANGNPKPR-----ISWLTNGVPIEIAPDDPSRKIDGDT--IIFSNVQERSSAVYQCNA 434
Query: 199 TS----MVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGN 254
++ ++ NA V V+ E P+I L+C G+
Sbjct: 435 SNEYGYLLANAFV------------NVLAE-PPRILTPANTLYQVIANRPALLDCAFFGS 481
Query: 255 PIPQINW-RRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLT 313
P+P I W + + G I + +G LEIP Q++ G+Y C+A N G +A+ +
Sbjct: 482 PLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLG--MAKNEVH 539
Query: 314 YYAK-PHWVQLIKDVEIAV---EDSLYWECRASGKPKPSYR--WLKNGAALVLEERTQIE 367
K P W+ +K E AV + +EC+ S WLK+ L +ER ++
Sbjct: 540 LEIKDPTWI--VKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVD 597
Query: 368 NGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAP------DFSKNPMKKLVQV 421
L ++++S DSG + C+A V +SA L VVA P D P +
Sbjct: 598 KDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTD 657
Query: 422 QVGSLVSLDCKP---RASP------RALSSWKKGDVSVQEHERISLLNDGGLKIANVTKA 472
Q+ V L P SP + K + + E LK++
Sbjct: 658 QLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNY 717
Query: 473 DAGTYTCMAENQFGKA--NGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLD 530
++ MA N GK+ + + +T+ + P+ ++ E +
Sbjct: 718 ---SFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPD------------N 762
Query: 531 IIFTWYFNGALADFKKDG-------SHFEKVGGSSSGDLMIRNI-QLKHSG-----KYVC 577
++ TW L F+ +G S +K G +++ N+ + SG Y+
Sbjct: 763 LVITW---KPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLI 819
Query: 578 MVQTGVDSVSSAADLIVRGSPG------PPENVKVDEITDTTAQLSWKEG--KDNHSPVI 629
VQ D + +V G G P NV+V+ + T A++ W K +
Sbjct: 820 KVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQ 879
Query: 630 SYSIQARTPFSVGWQTVTTVPEVI----DGKTHTATVVELNPWVEYEFRVVASNKIGGGE 685
Y I S + + + I KTH + L P+ Y V N G G
Sbjct: 880 GYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTH-GMLPGLEPFSHYTLNVRVVNGKGEG- 937
Query: 686 PSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGV 745
P+ P T E VP PS + + L + WDP NG Y + ++P+
Sbjct: 938 PASPDRVFNTPEGVPSA-PSSLKIVNPTLDSLTLEWDPPSH--PNGILTEYTLKYQPINS 994
Query: 746 TTWIQTVV---TSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVT-TVFSAEEE 801
T + +V + R+ +N + K Y G S +T + +E
Sbjct: 995 THELGPLVDLKIPANKTRWTLKNLNF----STRYKFYFYAQTSAGSGSQITEEAVTTVDE 1050
Query: 802 PTVAPSQVSANSLSSSEIEVS---------WNTIPWKLSNGHLLGYEVRYWNGGGKEESS 852
+ P V A + + +S + I W+ + + V Y G KEE
Sbjct: 1051 AGILPPDVGAGKVQAVNPRISNLTAAAAETYANISWEYEGPEHVNFYVEYGVAGSKEEWR 1110
Query: 853 SKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAG 886
++ V G+ + L+GL AY V A +G
Sbjct: 1111 KEI-VNGSRSFFGLKGLMPGTAYKVRVGAVGDSG 1143
Score = 83.6 bits (205), Expect = 9e-16
Identities = 94/393 (23%), Positives = 158/393 (40%), Gaps = 48/393 (12%)
Query: 227 PKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSD---GLPFSSKIKLRKFSGVLE 283
P I Q P+ + ++C A G P P +W R+ + + ++ +G L
Sbjct: 46 PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLI 105
Query: 284 IPNFQQEDA----GSYECIAENSRGKNVARGRLTYYAK-PHWV-QLIKDVEIAVEDSLYW 337
I + A G Y+C A N RG V+ + ++ P W + ++ + + SL
Sbjct: 106 INIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVL 165
Query: 338 ECRAS-GKPKPSYRWLKNG-AALVLEER-TQIENGALTISNLSVTDSGM-FQCIAENKHG 393
CR G P P W+ N L ER +Q NG L SN+ D+ + C A H
Sbjct: 166 PCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHT 225
Query: 394 LVYSSAE---LKVVA------------------SAPDFSKNPMKKLV--------QVQVG 424
+ +KV++ A + P L + G
Sbjct: 226 QTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRG 285
Query: 425 SLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQ 484
+++SL+C P + W K D + ++ + + L+I +V++AD+G Y C+A+N
Sbjct: 286 NVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNA 345
Query: 485 FGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADF 544
G + T + V AP N+ +S GE L C+ +P I +W NG +
Sbjct: 346 LGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRI--SWLTNGVPIEI 403
Query: 545 KKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVC 577
D K+ G + ++ N+Q + S Y C
Sbjct: 404 APDDPS-RKIDGDT---IIFSNVQERSSAVYQC 432
>gi|237858679 neurofascin isoform 3 precursor [Homo sapiens]
Length = 1174
Score = 363 bits (932), Expect = e-100
Identities = 274/975 (28%), Positives = 424/975 (43%), Gaps = 87/975 (8%)
Query: 4 PWKQLILLSFIGCLGGEL-----LLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSP 58
PW L + LGG + L Q P K+ + V D I + CEA+GNP+P
Sbjct: 8 PWVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHI-VDPRDN-ILIECEAKGNPAP 65
Query: 59 HYRWQLNGSDIDMSMEHRYKLN--GGNLVV---INPNRNWDTGTYQCFATNSLGTIVSRE 113
+ W N +++ + R + G LV+ G YQCFA N GT +S
Sbjct: 66 SFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNR 125
Query: 114 AKLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRF 173
+LQ + + + V V+EG + L C PPP W+ + ++ +R
Sbjct: 126 IRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD--KRV 183
Query: 174 VSQETGHLYISKVEPSDVG-NYTCVVTSMVTNARVLGSPTPLVLRSD------------- 219
G LY S V D+ +Y+C T+ +P L + ++
Sbjct: 184 SQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPD 243
Query: 220 --GVMGEYEPKIEVQFPETLPAA----KGSTVKLECFALGNPIPQINWRRSDGLPFSSKI 273
G E +P+ ++ +G + LEC A G P P I W + G S K
Sbjct: 244 MYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKA 303
Query: 274 KLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVED 333
K F+ L I N +ED+G Y C+A N G + A P+W+ K++ +A +
Sbjct: 304 KFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGE 363
Query: 334 SLYWECRASGKPKPSYRWLKNGAALVL---EERTQIENGALTISNLSVTDSGMFQCIAEN 390
CRA+G PKP+ +W+ NG L ++ + + ++ ++QC N
Sbjct: 364 DGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSN 423
Query: 391 KHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSW-KKGDVS 449
+HG + ++A + V+ P +P +L++V + + LDC SP W K G S
Sbjct: 424 EHGYLLANAFVSVL-DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGS 482
Query: 450 VQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNM 509
+ + +G L+I + K D G YTC+A N GKA L V +PTRI P +
Sbjct: 483 NLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQ 542
Query: 510 DVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKD-----GSHFEKVGGSSSGDLMI 564
G +V L C+V+HDP L + +W K D G+ +K S L I
Sbjct: 543 VARRGTTVQLECRVKHDPSLKLTVSW--------LKDDEPLYIGNRMKKEDDS----LTI 590
Query: 565 RNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKDN 624
+ + G Y C+ T +D + A L V G P P ++++ ++ + + +L+W G N
Sbjct: 591 FGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRDLELTDLAERSVRLTWIPGDAN 650
Query: 625 HSPVISYSIQ-ARTPFSVG-WQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIG 682
+SP+ Y +Q F G W + P ++ + V+ L+P+V Y+FRV+A N++G
Sbjct: 651 NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVN-----SAVLRLSPYVNYQFRVIAINEVG 705
Query: 683 GGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRP 742
PSLPSE+ RT A PE P +V G G ++ + ITW P+ G Y+V +R
Sbjct: 706 SSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRR 765
Query: 743 L-------GVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTV 795
VT W V TP YV PYE++V N+ G+GP
Sbjct: 766 RETREAWNNVTVWGSRYVVG-QTPVYV----------PYEIRVQAENDFGKGPEPESVIG 814
Query: 796 FSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGG--KEESSS 853
+S E+ P AP++V ++S+ I + WN + G L Y YW K S
Sbjct: 815 YSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVS 874
Query: 854 KMKVAGNETSARLRGLKSNLAYYTAVR----AYNSAGAGPFSATVNVTTKKTPPSQPPGN 909
+ + + RLRG+ S L Y+ + N G GP S T TT + PS P
Sbjct: 875 QKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRF 934
Query: 910 VVWNATDTKVLLNWE 924
V + L W+
Sbjct: 935 RVRQPNLETINLEWD 949
Score = 32.0 bits (71), Expect = 3.1
Identities = 27/107 (25%), Positives = 39/107 (36%), Gaps = 6/107 (5%)
Query: 596 GSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQ--ARTPFSVGWQTVTTVPEVI 653
G P P +V + T L W + + +I Y+++ A VG Q V E
Sbjct: 926 GVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIV----ENF 981
Query: 654 DGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVP 700
TV +P Y F + A ++G GE EA P
Sbjct: 982 SPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATP 1028
>gi|89903008 neurofascin isoform 4 precursor [Homo sapiens]
Length = 1169
Score = 363 bits (932), Expect = e-100
Identities = 274/975 (28%), Positives = 424/975 (43%), Gaps = 87/975 (8%)
Query: 4 PWKQLILLSFIGCLGGEL-----LLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSP 58
PW L + LGG + L Q P K+ + V D I + CEA+GNP+P
Sbjct: 8 PWVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHI-VDPRDN-ILIECEAKGNPAP 65
Query: 59 HYRWQLNGSDIDMSMEHRYKLN--GGNLVV---INPNRNWDTGTYQCFATNSLGTIVSRE 113
+ W N +++ + R + G LV+ G YQCFA N GT +S
Sbjct: 66 SFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNR 125
Query: 114 AKLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRF 173
+LQ + + + V V+EG + L C PPP W+ + ++ +R
Sbjct: 126 IRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD--KRV 183
Query: 174 VSQETGHLYISKVEPSDVG-NYTCVVTSMVTNARVLGSPTPLVLRSD------------- 219
G LY S V D+ +Y+C T+ +P L + ++
Sbjct: 184 SQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPD 243
Query: 220 --GVMGEYEPKIEVQFPETLPAA----KGSTVKLECFALGNPIPQINWRRSDGLPFSSKI 273
G E +P+ ++ +G + LEC A G P P I W + G S K
Sbjct: 244 MYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKA 303
Query: 274 KLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVED 333
K F+ L I N +ED+G Y C+A N G + A P+W+ K++ +A +
Sbjct: 304 KFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGE 363
Query: 334 SLYWECRASGKPKPSYRWLKNGAALVL---EERTQIENGALTISNLSVTDSGMFQCIAEN 390
CRA+G PKP+ +W+ NG L ++ + + ++ ++QC N
Sbjct: 364 DGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSN 423
Query: 391 KHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSW-KKGDVS 449
+HG + ++A + V+ P +P +L++V + + LDC SP W K G S
Sbjct: 424 EHGYLLANAFVSVL-DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGS 482
Query: 450 VQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNM 509
+ + +G L+I + K D G YTC+A N GKA L V +PTRI P +
Sbjct: 483 NLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQ 542
Query: 510 DVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKD-----GSHFEKVGGSSSGDLMI 564
G +V L C+V+HDP L + +W K D G+ +K S L I
Sbjct: 543 VARRGTTVQLECRVKHDPSLKLTVSW--------LKDDEPLYIGNRMKKEDDS----LTI 590
Query: 565 RNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKDN 624
+ + G Y C+ T +D + A L V G P P ++++ ++ + + +L+W G N
Sbjct: 591 FGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRDLELTDLAERSVRLTWIPGDAN 650
Query: 625 HSPVISYSIQ-ARTPFSVG-WQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIG 682
+SP+ Y +Q F G W + P ++ + V+ L+P+V Y+FRV+A N++G
Sbjct: 651 NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVN-----SAVLRLSPYVNYQFRVIAINEVG 705
Query: 683 GGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRP 742
PSLPSE+ RT A PE P +V G G ++ + ITW P+ G Y+V +R
Sbjct: 706 SSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRR 765
Query: 743 L-------GVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTV 795
VT W V TP YV PYE++V N+ G+GP
Sbjct: 766 RETREAWNNVTVWGSRYVVG-QTPVYV----------PYEIRVQAENDFGKGPEPESVIG 814
Query: 796 FSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGG--KEESSS 853
+S E+ P AP++V ++S+ I + WN + G L Y YW K S
Sbjct: 815 YSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVS 874
Query: 854 KMKVAGNETSARLRGLKSNLAYYTAVR----AYNSAGAGPFSATVNVTTKKTPPSQPPGN 909
+ + + RLRG+ S L Y+ + N G GP S T TT + PS P
Sbjct: 875 QKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRF 934
Query: 910 VVWNATDTKVLLNWE 924
V + L W+
Sbjct: 935 RVRQPNLETINLEWD 949
Score = 30.8 bits (68), Expect = 6.9
Identities = 28/111 (25%), Positives = 43/111 (38%), Gaps = 12/111 (10%)
Query: 596 GSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQ--ARTPFSVGWQTVTTVPEVI 653
G P P +V + T L W + + +I Y+++ A VG Q V E
Sbjct: 926 GVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIV----ENF 981
Query: 654 DGKTHTATVVELNPWVEYEFRVVASNKIGGGE------PSLPSEKVRTEEA 698
TV +P Y F + A ++G GE P+ P+E +A
Sbjct: 982 SPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEAYTNNQA 1032
>gi|237858677 neurofascin isoform 2 precursor [Homo sapiens]
Length = 1189
Score = 355 bits (910), Expect = 2e-97
Identities = 274/990 (27%), Positives = 425/990 (42%), Gaps = 102/990 (10%)
Query: 4 PWKQLILLSFIGCLGGEL-----LLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSP 58
PW L + LGG + L Q P K+ + V D I + CEA+GNP+P
Sbjct: 8 PWVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHI-VDPRDN-ILIECEAKGNPAP 65
Query: 59 HYRWQLNGSDIDMSMEHRYKLN--GGNLVV---INPNRNWDTGTYQCFATNSLGTIVSRE 113
+ W N +++ + R + G LV+ G YQCFA N GT +S
Sbjct: 66 SFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNR 125
Query: 114 AKLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRF 173
+LQ + + + V V+EG + L C PPP W+ + ++ +R
Sbjct: 126 IRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD--KRV 183
Query: 174 VSQETGHLYISKVEPSDVG-NYTCVVTSMVTNARVLGSPTPLVLRSD------------- 219
G LY S V D+ +Y+C T+ +P L + ++
Sbjct: 184 SQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPD 243
Query: 220 --GVMGEYEPKIEVQFPETLPAA----KGSTVKLECFALGNPIPQINWRRSDGLPFSSKI 273
G E +P+ ++ +G + LEC A G P P I W + G S K
Sbjct: 244 MYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKA 303
Query: 274 KLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVED 333
K F+ L I N +ED+G Y C+A N G + A P+W+ K++ +A +
Sbjct: 304 KFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGE 363
Query: 334 SLYWECRASGKPKPSYRWLKNGAALVL---EERTQIENGALTISNLSVTDSGMFQCIAEN 390
CRA+G PKP+ +W+ NG L ++ + + ++ ++QC N
Sbjct: 364 DGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSN 423
Query: 391 KHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSW-KKGDVS 449
+HG + ++A + V+ P +P +L++V + + LDC SP W K G S
Sbjct: 424 EHGYLLANAFVSVL-DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGS 482
Query: 450 VQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNM 509
+ + +G L+I + K D G YTC+A N GKA L V +PTRI P +
Sbjct: 483 NLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQ 542
Query: 510 DVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKD-----GSHFEKVGGSSSGDLMI 564
G +V L C+V+HDP L + +W K D G+ +K S L I
Sbjct: 543 VARRGTTVQLECRVKHDPSLKLTVSW--------LKDDEPLYIGNRMKKEDDS----LTI 590
Query: 565 RNIQLKHSGKYVCMVQTGVDSVSSAADLIV---------------RGSPGPPENVKVDEI 609
+ + G Y C+ T +D + A L V +G P P ++++ ++
Sbjct: 591 FGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDL 650
Query: 610 TDTTAQLSWKEGKDNHSPVISYSIQ-ARTPFSVG-WQTVTTVPEVIDGKTHTATVVELNP 667
+ + +L+W G N+SP+ Y +Q F G W + P ++ + V+ L+P
Sbjct: 651 AERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVN-----SAVLRLSP 705
Query: 668 WVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEE 727
+V Y+FRV+A N++G PSLPSE+ RT A PE P +V G G ++ + ITW P+
Sbjct: 706 YVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNAT 765
Query: 728 LQNGEGFGYVVAFRPL-------GVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGV 780
G Y+V +R VT W V TP YV PYE++V
Sbjct: 766 SAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVG-QTPVYV----------PYEIRVQA 814
Query: 781 YNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEV 840
N+ G+GP +S E+ P AP++V ++S+ I + WN + G L Y
Sbjct: 815 ENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRA 874
Query: 841 RYWNGGG--KEESSSKMKVAGNETSARLRGLKSNLAYYTAVR----AYNSAGAGPFSATV 894
YW K S+ + + RLRG+ S L Y+ + N G GP S T
Sbjct: 875 YYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETK 934
Query: 895 NVTTKKTPPSQPPGNVVWNATDTKVLLNWE 924
TT + PS P V + L W+
Sbjct: 935 EFTTPEGVPSAPRRFRVRQPNLETINLEWD 964
Score = 32.0 bits (71), Expect = 3.1
Identities = 27/107 (25%), Positives = 39/107 (36%), Gaps = 6/107 (5%)
Query: 596 GSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQ--ARTPFSVGWQTVTTVPEVI 653
G P P +V + T L W + + +I Y+++ A VG Q V E
Sbjct: 941 GVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIV----ENF 996
Query: 654 DGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVP 700
TV +P Y F + A ++G GE EA P
Sbjct: 997 SPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATP 1043
>gi|28373124 contactin 4 isoform b precursor [Homo sapiens]
Length = 282
Score = 339 bits (869), Expect = 9e-93
Identities = 159/275 (57%), Positives = 214/275 (77%), Gaps = 1/275 (0%)
Query: 748 WIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPS 807
W+ TV+ S D RYVFRNES+ P+SP+EVKVGV+NNKGEGPFSP T V+SAEEEPT P+
Sbjct: 3 WMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPA 62
Query: 808 QVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNETSARLR 867
+ A SLS+++IEV W + P + + G + GYEV+YW KEE++ K++ GN+TS ++
Sbjct: 63 SIFARSLSATDIEVFWAS-PLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKIT 121
Query: 868 GLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVK 927
LK ++ Y+ AV+AYNSAG GP SATVNVTT+K PPSQPPGN++WN++D+K++LNW+QVK
Sbjct: 122 NLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVK 181
Query: 928 AMENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELVLPIKEDYIIEVKATTDGGDGTSSE 987
A++NESEV GYKV YR + Q++ V+ TNKTS EL LP EDYIIE+K +DGGDG+SSE
Sbjct: 182 ALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSE 241
Query: 988 QIRIPRITSMDARGSTSAISNVHPMSSYMPIVLFL 1022
QIRIP+I++ ARGS ++ SN +S+ I++ L
Sbjct: 242 QIRIPKISNAYARGSGASTSNACTLSAISTIMISL 276
Score = 60.5 bits (145), Expect = 8e-09
Identities = 63/261 (24%), Positives = 104/261 (39%), Gaps = 33/261 (12%)
Query: 648 TVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEV 707
TV D + ++P+ +E +V N G G P P+ V + E P PP+ +
Sbjct: 6 TVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEG-PFSPTTVVYSAEEEPTKPPASI 64
Query: 708 NGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGVTTW-----------IQTVVTSP 756
S +++ + W P E G GY V + W I+TV
Sbjct: 65 FARSLSATDIEVFW-ASPLEKNRGRIQGYEVKY-------WRHEDKEENARKIRTVGNQT 116
Query: 757 DTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSS 816
T + + Y + V YN+ G GP S V + + P+ P + NS S
Sbjct: 117 STKITNLKGSVL-----YHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNS-SD 170
Query: 817 SEIEVSWNTIPWKLSNGHLLGYEVRY-WNGGGKEESSSKMKVAGNETSARLRGLKSNLAY 875
S+I ++W+ + + + GY+V Y WN SS + N+TS L L + Y
Sbjct: 171 SKIILNWDQVKALDNESEVKGYKVLYRWN-----RQSSTSVIETNKTSVEL-SLPFDEDY 224
Query: 876 YTAVRAYNSAGAGPFSATVNV 896
++ ++ G G S + +
Sbjct: 225 IIEIKPFSDGGDGSSSEQIRI 245
Score = 37.4 bits (85), Expect = 0.073
Identities = 46/188 (24%), Positives = 72/188 (38%), Gaps = 29/188 (15%)
Query: 600 PPENVKVDEITDTTAQLSWKEGKD-NHSPVISYSIQ----------ARTPFSVGWQTVTT 648
PP ++ ++ T ++ W + N + Y ++ AR +VG QT T
Sbjct: 60 PPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTK 119
Query: 649 VPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVN 708
+ L V Y V A N G G PS + V T + P PP +
Sbjct: 120 I-------------TNLKGSVLYHLAVKAYNSAGTG-PSSATVNVTTRKPPPSQPPGNII 165
Query: 709 GGGGSRSELVITWDPVPEELQNGEGFGYVVAFR--PLGVTTWIQTVVTSPDTPRYVFRNE 766
S S++++ WD V E GY V +R T+ I+T TS + F +
Sbjct: 166 WNS-SDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVEL-SLPFDED 223
Query: 767 SIVPYSPY 774
I+ P+
Sbjct: 224 YIIEIKPF 231
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 331 bits (848), Expect = 2e-90
Identities = 289/1017 (28%), Positives = 454/1017 (44%), Gaps = 63/1017 (6%)
Query: 26 PVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDID-MSMEHRYKLNGGNL 84
P F EP + V E ++ L C A G+ ++W N ++ S+E+RY
Sbjct: 26 PYFKTEPVRT--QVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRY------- 76
Query: 85 VVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLC 144
+I G Y+C N +G ++ R+ ++Q AY+ +F+ + SV G+ V+
Sbjct: 77 -MITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQ-SVSHGEAAVIRA 134
Query: 145 GPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVVTSMVTN 204
+ W + + SR ++ E + +S V P D G Y +
Sbjct: 135 PRIASFPQPQVTWFRDGRK--IPPSSRIAITLENTLVILSTVAP-DAGRYYVQAVNDKNG 191
Query: 205 ARVLGSPTPLVLRSDGVMGE-YEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQIN--W 261
P L + + G + P I + T A S V LEC A P+ +++ W
Sbjct: 192 DNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIW 251
Query: 262 RRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYEC--IAENSRGKNVARGRLTYYAKPH 319
++ DG+ S I + L IPN DAG YEC + +S +V RG +P
Sbjct: 252 KK-DGVLLSGGIS--DHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPP 308
Query: 320 WVQLIKDVE----IAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERT---QIENGALT 372
Q +K+ E +E + C+A G P PS W K+ A + +E+ T Q +G L
Sbjct: 309 --QFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQ 366
Query: 373 ISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCK 432
IS L D+GMFQC A N G V +S L V + AP+ ++ P+ V G V L C+
Sbjct: 367 ISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVID--GMSVVLACE 424
Query: 433 PRASPRALSSWKKGDVSVQEHE----RISLLNDGGLKIANVTKADAGTYTCMAENQFGKA 488
+PR +W+KG+ + R + L G L I+ +DAGTYTC+A N G
Sbjct: 425 TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVD 484
Query: 489 NGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDG 548
+ LVV TRIT P + V G + C V HDP + I + W +GA +
Sbjct: 485 EASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTE--- 541
Query: 549 SHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPEN--VKV 606
SH ++ +G L I G Y C V + + S +A L VR P PE+ +
Sbjct: 542 SH-PRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATL 600
Query: 607 DEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELN 666
+ L+W + D +SP+I Y ++ + + W T + +D K + TV L
Sbjct: 601 STVERRAINLTWTKPFDGNSPLIRYILEM-SENNAPW---TVLLASVDPKATSVTVKGLV 656
Query: 667 PWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPE 726
P Y+FR+ A N +G G+ S +E+V E P PP V G + ++I W P PE
Sbjct: 657 PARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPE 716
Query: 727 ELQNGEGFGYVVAFRPLGVTTWIQ-TVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKG 785
QNG GY++ + G+ Q +T D + E ++ ++ YE++V YN+ G
Sbjct: 717 SHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLL--EDLIIWTNYEIEVAAYNSAG 774
Query: 786 EGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNG 845
G +S T ++ + PTV P V A + +S+ I +WN + NG GY++ W
Sbjct: 775 LGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEP 834
Query: 846 GGKEESSSKMKVAGNETSAR---LRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTP 902
+EE + + S + GLK Y+T+V + + G GP S V T +
Sbjct: 835 EQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDV 894
Query: 903 PSQPPGNVVWN-ATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVLN--TNKTS 959
P P G++ ++ DT + ++W++ E +TGY++ + ++ N +V + N T
Sbjct: 895 PG-PVGHLSFSEILDTSLKVSWQE--PGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTL 951
Query: 960 AELV--LPIKEDYIIEVKATTDGGDG-TSSEQIRIPRITSMDARGSTSAISNVHPMS 1013
V L Y IEV A T G G S+ I + + ISN+ P S
Sbjct: 952 EYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRS 1008
Score = 157 bits (396), Expect = 6e-38
Identities = 111/376 (29%), Positives = 175/376 (46%), Gaps = 31/376 (8%)
Query: 595 RGSPGPPEN--VKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEV 652
R P PP V+ +++ + LSW+ G D SPV Y+IQ R S W +
Sbjct: 1397 RDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSAS--- 1453
Query: 653 IDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGG 712
+ + V L P+ Y+FRV A+N IG E S SE + T +A P+ P+ ++
Sbjct: 1454 VSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPH 1513
Query: 713 SRSELVITWDPVPEELQNGEGFGYVVAFRPL---GVTTWIQTVVTSPD------TPRYVF 763
+ + ++I W P E+ NG G+ + +R L G+ + + +P T Y
Sbjct: 1514 TTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSM 1573
Query: 764 RN-----------ESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSAN 812
RN +++ + YE+++ VYN GEGP SP VF E PT AP V +
Sbjct: 1574 RNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVH 1633
Query: 813 SLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNG--GGKEESSSKMKVAGNETSARLRGLK 870
++++++V+W P NG + GY++ +W G E + +A E S +L+ L
Sbjct: 1634 GATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLA--ENSVKLKNLT 1691
Query: 871 SNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAME 930
AY +V A+N+AG GP S T++ PS P T T V ++WE +
Sbjct: 1692 GYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPN 1751
Query: 931 NESEVTGYKVFYRTSS 946
E GY++ Y S
Sbjct: 1752 GILE--GYRLVYEPCS 1765
Score = 132 bits (332), Expect = 2e-30
Identities = 119/433 (27%), Positives = 189/433 (43%), Gaps = 40/433 (9%)
Query: 582 GVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSV 641
G S S+ + + PGPP N+ + I + L ++ G D + + + ++A+ V
Sbjct: 977 GQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGV-V 1035
Query: 642 G----WQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEE 697
G W + + D ++ V +LNP+ Y FR+ N +G PS PS K++T +
Sbjct: 1036 GEGEEWLLIHQLSNEPDARS--MEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQ 1093
Query: 698 AVPEVPPSEVNGGGGSRSELVITWDPVPEELQNG--EGFGYVVAF-RPLGVTTWIQTVVT 754
A P++ P+ V+ S + L + W P+PE NG E GY + + R G + VV
Sbjct: 1094 APPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQ 1153
Query: 755 SPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSL 814
Y E + ++ Y V+V +N G GP+S + E P+ P+ VSA +
Sbjct: 1154 DRVERDYTI--EDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALAT 1211
Query: 815 SSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMK----VAGNET-SARLRGL 869
+SS + V W+ +P NG +LGY+V Y KE+ S V GN + SA+L GL
Sbjct: 1212 TSSSMLVRWSEVPEADRNGLVLGYKVMY-----KEKDSDTQPRFWLVEGNSSRSAQLTGL 1266
Query: 870 KSNLAYYTAVRAYNSAGAG-PFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKA 928
+ Y V A+ G G P + T P P G + T V L W+ A
Sbjct: 1267 GKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAA 1326
Query: 929 MENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELVLPIKEDYIIEVKATTDGGDGTSSEQ 988
G + Y+ + + N NT + E++ P Y G E
Sbjct: 1327 ------PNGIILAYQITHRLNTTTANT--ATVEVLAPSARQYT---------ATGLKPES 1369
Query: 989 IRIPRITSMDARG 1001
+ + RIT+ +G
Sbjct: 1370 VYLFRITAQTRKG 1382
Score = 99.8 bits (247), Expect = 1e-20
Identities = 111/476 (23%), Positives = 188/476 (39%), Gaps = 53/476 (11%)
Query: 551 FEKVGGSSSGDLMIRNIQLKHSGKYVCM---------VQTGVDSVSSAADLIVRGSPGPP 601
F V G+SS R+ QL GKYV + G S + + PGPP
Sbjct: 1250 FWLVEGNSS-----RSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPP 1304
Query: 602 ENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTAT 661
+ E+ T+ +L W+ + +++Y I R + T EV+ T
Sbjct: 1305 MGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTA---NTATVEVLAPSARQYT 1361
Query: 662 VVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSE--VNGGGGSRSELVI 719
L P Y FR+ A + G GE + + V TE+ PPS V +++
Sbjct: 1362 ATGLKPESVYLFRITAQTRKGWGEAA-EALVVTTEKRDRPQPPSRPMVQQEDVRARSVLL 1420
Query: 720 TWDPVPEELQNGEGFGYVVAFRPLGVTTW-IQTVVTSPDTPRYVFRNESIVPYSPYEVKV 778
+W+P + L Y + R L W + + S + ++ + + P++ Y+ +V
Sbjct: 1421 SWEPGSDGLSPVRY--YTIQTRELPSGRWALHSASVSHNASSFIV--DRLKPFTSYKFRV 1476
Query: 779 GVYNNKGEGPFSPVT-TVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLG 837
N+ G+ FS + ++ + + P AP+ +S +++ + + W NG LLG
Sbjct: 1477 KATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLG 1536
Query: 838 YEVRYW----------------NGGGKEESSSKMKVAGNE-----TSARLRGLKSNLAYY 876
+ +RY N G + M N T L L + Y
Sbjct: 1537 FRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYE 1596
Query: 877 TAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWN-ATDTKVLLNWEQVKAMENESEV 935
+ YN+ G GP S V + P+ P NVV + AT T++ + WE ++
Sbjct: 1597 IRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDI 1656
Query: 936 TGYKVFYRTSSQNNVQVLNTNKTSAELVLPIKE-----DYIIEVKATTDGGDGTSS 986
GYK+++ + + N+ AE + +K Y++ V A GDG S
Sbjct: 1657 QGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRS 1712
Score = 93.2 bits (230), Expect = 1e-18
Identities = 100/400 (25%), Positives = 169/400 (42%), Gaps = 21/400 (5%)
Query: 601 PENVKVDEITDTTAQLSWK---EGKDNHSPV-ISYSIQARTPFSVGWQTVTTVPEVIDGK 656
P NV + ++T+ L W E + N +P + Y I+ G +T++ V V D
Sbjct: 1100 PANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHG-KTLSHV--VQDRV 1156
Query: 657 THTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSE 716
T+ +L W EY +V A N IG G P + RT E+VP P+ V+ + S
Sbjct: 1157 ERDYTIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRTRESVPSSGPTNVSALATTSSS 1215
Query: 717 LVITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEV 776
+++ W VPE +NG GY V ++ T + + ++ R + + Y YEV
Sbjct: 1216 MLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA-QLTGLGKYVLYEV 1274
Query: 777 KVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLL 836
+V + G+G S + ++ P + + ++ + + W P NG +L
Sbjct: 1275 QVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQ--PPAAPNGIIL 1332
Query: 837 GYEVRYWNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNV 896
Y++ + +++ +A + GLK Y + A G G + + V
Sbjct: 1333 AYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVV 1392
Query: 897 TTKKTPPSQPPGNVVWNATDTK---VLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVL 953
TT+K QPP + D + VLL+WE + S V Y + R +
Sbjct: 1393 TTEKRDRPQPPSRPMVQQEDVRARSVLLSWEP--GSDGLSPVRYYTIQTRELPSGRWALH 1450
Query: 954 N---TNKTSAELVLPIKE--DYIIEVKATTDGGDGTSSEQ 988
+ ++ S+ +V +K Y VKAT D GD SE+
Sbjct: 1451 SASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEE 1490
Score = 58.2 bits (139), Expect = 4e-08
Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 596 GSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQT-VTTVPEVID 654
G+PGPP V + + + W G P+ Y I+AR W + +P+ +
Sbjct: 1823 GAPGPP-GVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVS 1881
Query: 655 GKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVP 700
T + + L P V Y+FRV+A N G G PS PS+ V ++A P
Sbjct: 1882 SYTFSMDI--LKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
>gi|237858675 neurofascin isoform 1 precursor [Homo sapiens]
Length = 1240
Score = 330 bits (846), Expect = 4e-90
Identities = 261/968 (26%), Positives = 415/968 (42%), Gaps = 99/968 (10%)
Query: 4 PWKQLILLSFIGCLGGEL-----------LLQGPVFIKEPSNSIFPVGSEDKKITLHCEA 52
PW L + LGG + L Q P K+ + V D I + CEA
Sbjct: 8 PWVHAAFLLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHI-VDPRDN-ILIECEA 65
Query: 53 RGNPSPHYRWQLNGSDIDMSMEHRYKLN--GGNLVV---INPNRNWDTGTYQCFATNSLG 107
+GNP+P + W N +++ + R + G LV+ G YQCFA N G
Sbjct: 66 KGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFG 125
Query: 108 TIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVE 167
T +S +LQ + + + V V+EG + L C PPP W+ + +
Sbjct: 126 TALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQ 185
Query: 168 EDSRRFVSQETGHLYISKVEPSDVG-NYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYE 226
+ +R G LY S V D+ +Y+C T+ + P L+ G E
Sbjct: 186 D--KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHT--IQQKNPFTLKVLTTRGVAE 241
Query: 227 PKIEVQFPETLPAA----KGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVL 282
+P+ ++ +G + LEC A G P P I W + G S K K F+ L
Sbjct: 242 RTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKAL 301
Query: 283 EIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRAS 342
I N +ED+G Y C+A N G + A P+W+ K++ +A + CRA+
Sbjct: 302 RITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRAN 361
Query: 343 GKPKPSYRWLKNGAALVL---EERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSA 399
G PKP+ +W+ NG L ++ + + ++ ++QC N+HG + ++A
Sbjct: 362 GNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANA 421
Query: 400 ELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSW-KKGDVSVQEHERISL 458
+ V+ P +P +L++V + + LDC SP W K G S + +
Sbjct: 422 FVSVL-DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHV 480
Query: 459 LNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVI 518
+G L+I + K D G YTC+A N GKA L V +PTRI P + G +V
Sbjct: 481 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 540
Query: 519 LPCQVQHDPLLDIIFTWYFNGALADFKKD-----GSHFEKVGGSSSGDLMIRNIQLKHSG 573
L C+V+HDP L + +W K D G+ +K S L I + + G
Sbjct: 541 LECRVKHDPSLKLTVSW--------LKDDEPLYIGNRMKKEDDS----LTIFGVAERDQG 588
Query: 574 KYVCMVQTGVDSVSSAADLIV---------------RGSPGPPENVKVDEITDTTAQLSW 618
Y C+ T +D + A L V +G P P ++++ ++ + + +L+W
Sbjct: 589 SYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTW 648
Query: 619 KEGKDNHSPVISYSIQ-ARTPFSVG-WQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVV 676
G N+SP+ Y +Q F G W + P ++ + V+ L+P+V Y+FRV+
Sbjct: 649 IPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVN-----SAVLRLSPYVNYQFRVI 703
Query: 677 ASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGY 736
A N++G PSLPSE+ RT A PE P +V G G ++ + ITW P+ G Y
Sbjct: 704 AINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY 763
Query: 737 VVAFRPL-------GVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPF 789
+V +R VT W V TP YV PYE++V N+ G+GP
Sbjct: 764 IVKWRRRETREAWNNVTVWGSRYVVG-QTPVYV----------PYEIRVQAENDFGKGPE 812
Query: 790 SPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKE 849
+S E+ P+ AP + + I + W+ + NG ++GY ++Y G +
Sbjct: 813 PESVIGYSGEDLPS-APRRFRVRQPNLETINLEWDHP--EHPNGIMIGYTLKYVAFNGTK 869
Query: 850 ESSSKMK-VAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPF------SATVNVTTKKTP 902
++ + N+T ++ Y + A G+G + T P
Sbjct: 870 VGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAP 929
Query: 903 PSQPPGNV 910
P+ PP V
Sbjct: 930 PTLPPTTV 937
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 301 bits (772), Expect = 2e-81
Identities = 276/1030 (26%), Positives = 439/1030 (42%), Gaps = 88/1030 (8%)
Query: 26 PVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDIDM-SMEHRYKLNGGNL 84
P F EP + + E ++ L C A G+ ++W + S++ S E++Y
Sbjct: 104 PYFKTEPG--LPQIHLEGNRLVLTCLAEGSWPLEFKWMRDDSELTTYSSEYKY------- 154
Query: 85 VVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAYLENFK-TKMRSTVSVREGQGVVLL 143
+I + D G Y+C N +G ++ R++++Q AY+ +F T R TVS +G+ +L
Sbjct: 155 -IIPSLQKLDAGFYRCVVRNRMGALLQRKSEVQVAYMGSFMDTDQRKTVS--QGRAAILN 211
Query: 144 CGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVVTSMVT 203
P W F E + S R L I SD G Y V
Sbjct: 212 LLPITSYPRPQVTW-FREGHKIIP--SNRIAITLENQLVILATTTSDAGAY---YVQAVN 265
Query: 204 NARVLGSPTPLV----LRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQI 259
+P + R G P I V A S LEC A P+ +
Sbjct: 266 EKNGENKTSPFIHLSIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECIASARPVEDL 325
Query: 260 N--WRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAE--NSRGKNVARGRLTYY 315
+ W+R+ G+ +S L F L I N D G Y C A S + +
Sbjct: 326 SVTWKRN-GVRITSG--LHSFGRRLTISNPTSADTGPYVCEAALPGSAFEPARATAFLFI 382
Query: 316 AKPHWVQLIKDVEIA--VEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQ---IENGA 370
+P + + I+ VE+++ C+A G P P+ +W K+ ++ + + + +G
Sbjct: 383 IEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGG 442
Query: 371 LTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLD 430
L I L DSG+FQC A N+ G + + L V AP F++ P+ V G L
Sbjct: 443 LRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVD--TTVTDGMTAILR 500
Query: 431 CKPRASPRALSSWKK-------GDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAEN 483
C+ +P+ +WK+ G V + R LL GGL+IA V DAG YTC A N
Sbjct: 501 CEVSGAPKPAITWKRENHILASGSVRIP---RFMLLESGGLQIAPVFIQDAGNYTCYAAN 557
Query: 484 QFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALAD 543
G N + L V T I P + V G + L C HDP + + + W
Sbjct: 558 TEGSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLRYVW-------- 609
Query: 544 FKKDG-----SHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSP 598
KKD S ++ G L+I G Y C + + + S A L V P
Sbjct: 610 -KKDNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELP 668
Query: 599 GPPENVKVDEITDTT--AQLSWKEGKDNHSPVISYSIQA---RTPFSVGWQTVTTVPEVI 653
P+N+ V + + LSW D +SP++ Y ++ +P+ V V PE+
Sbjct: 669 HSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVG--PEMT 726
Query: 654 DGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGS 713
TV L P Y+FRV A N++G G+ S + ++ E P PP + G +
Sbjct: 727 G-----VTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRT 781
Query: 714 RSELVITWDPVPEELQNGEGFGYVVAFRPLGVT-TWIQTVVTSPDTPRYVFRNESIVPYS 772
+++ W P PE NG GY++ +R G+ + Q +TSP+ Y + I+ ++
Sbjct: 782 NQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEV-NYCLVTDLII-WT 839
Query: 773 PYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSN 832
YE++V YN G G FS T ++ + PT P V +++S+ I+ WN P + N
Sbjct: 840 QYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFIN 899
Query: 833 GHLLGYEVRYWNGGGKEESSSKMKVAGN---ETSARLRGLKSNLAYYTAVRAYNSAGAGP 889
G GY++ W E+ + + +A + + LK AY+T+V + + G GP
Sbjct: 900 GINQGYKLLAWPADA-PEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGP 958
Query: 890 FSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNN 949
S V T++ P DT + ++W++ +E +TGY++ + +N+
Sbjct: 959 PSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQE--PLEKNGIITGYQISWEVYGRND 1016
Query: 950 VQVLNT-NKTSAELV---LPIKEDYIIEVKATTDGGDG-TSSEQIRIPRITSMDARGSTS 1004
++ +T N T+ E L Y I+V A T G G +S I + S
Sbjct: 1017 SRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISSGVPPDLPGAPSNL 1076
Query: 1005 AISNVHPMSS 1014
ISN+ P S+
Sbjct: 1077 VISNISPRSA 1086
Score = 151 bits (381), Expect = 3e-36
Identities = 107/371 (28%), Positives = 170/371 (45%), Gaps = 28/371 (7%)
Query: 595 RGSPGPPENVKVD--EITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEV 652
R P PP + V E+T + +L W G D SP+ +++Q R WQT ++
Sbjct: 1474 RERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSS--- 1530
Query: 653 IDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGG 712
I + V L P+ Y+ R+ A+N IG + S +E V T + VP PP V+
Sbjct: 1531 ISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPH 1590
Query: 713 SRSELVITWDPVPEELQNGEGFGYVVAFRPL----GVTTWIQTV---------VTSPDTP 759
+ S ++I W P +E NG GY + +R L G T +T+ +T+ +
Sbjct: 1591 TTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSF 1650
Query: 760 RYVFRNES--------IVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSA 811
+ V + + + Y YEV + YN GE P S VF E P +AP V
Sbjct: 1651 KTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQV 1710
Query: 812 NSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNETSARLRGLKS 871
L++S++EV+W+ P + NG++ GY++ YW + E+ + E RL+ L S
Sbjct: 1711 TPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTS 1770
Query: 872 NLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMEN 931
+ Y ++ A+N+AG GP S T + P P T T + ++W + A
Sbjct: 1771 HTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAA-- 1828
Query: 932 ESEVTGYKVFY 942
+ GY+V Y
Sbjct: 1829 NGILQGYRVVY 1839
Score = 137 bits (346), Expect = 4e-32
Identities = 115/423 (27%), Positives = 193/423 (45%), Gaps = 16/423 (3%)
Query: 576 VCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQA 635
V V TG+ + S+ + + PG P N+ + I+ +A L ++ G D + + + ++
Sbjct: 1048 VTAVGTGLVTSSTISSGVPPDLPGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEG 1107
Query: 636 RTPFSVGWQT--VTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKV 693
+ ++G + VT E + + L P+ Y FR+ N +G S S +
Sbjct: 1108 QVG-AIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVI 1166
Query: 694 RTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNG--EGFGYVVAFRPLGVTTWIQT 751
+T +A P+V P+ V S + L + W P+P+ NG E GY + + + +
Sbjct: 1167 QTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVA 1226
Query: 752 VVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSA 811
V S R F E + + YE+++ +N G GP+S V + E P+ AP VSA
Sbjct: 1227 QVVSDRLERE-FTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSA 1285
Query: 812 NSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNET-SARLRGLK 870
++SS++I ++W ++P + NG +LGY++ + E S + V GN T SA L GL+
Sbjct: 1286 EAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHI-VRGNHTQSALLAGLR 1344
Query: 871 SNLAYYTAVRAYNSAGAG-PFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAM 929
+ Y V A+ G G P + + TK P P V T V + W+ +
Sbjct: 1345 KFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPE-- 1402
Query: 930 ENESEVTGYKVFYRTSSQN-----NVQVLNTNKTSAELVLPIKEDYIIEVKATTDGGDGT 984
E + GY++ YR +S + V+V T + L + YI + A T G G
Sbjct: 1403 EPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGE 1462
Query: 985 SSE 987
E
Sbjct: 1463 PLE 1465
Score = 111 bits (277), Expect = 4e-24
Identities = 111/440 (25%), Positives = 176/440 (40%), Gaps = 38/440 (8%)
Query: 579 VQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTP 638
+ GV S + +PGPP + E+ T+ ++ W+ ++ + ++ Y I R
Sbjct: 1359 IGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLA 1418
Query: 639 FSVGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEA 698
S T TTV + TAT +L P Y FR+ A + G GEP L + + TE+
Sbjct: 1419 SSSP-HTFTTVEVGATVRQFTAT--DLAPESAYIFRLSAKTRQGWGEP-LEATVITTEKR 1474
Query: 699 VPEVPPSE--VNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSP 756
PP E V + L + W P + F V P G + ++
Sbjct: 1475 ERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHE 1534
Query: 757 DTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVT-TVFSAEEEPTVAPSQVSANSLS 815
T V R + P++ Y++++ N+ G+ FS T V + ++ P P VSA +
Sbjct: 1535 ATACVVDR---LRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHT 1591
Query: 816 SSEIEVSWNTIPWKLSNGHLLGY-----EVRYWNGGGKEESSSKMKVA------------ 858
+S + + W + NG L GY E+ Y G G E + K +A
Sbjct: 1592 TSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFK 1651
Query: 859 -----GNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNV-VW 912
T L LK Y + AYN G P SA V V + P+ P NV V
Sbjct: 1652 TVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVT 1711
Query: 913 NATDTKVLLNWEQVKAMENESEVTGYKVFY-RTSSQNNVQVLNTNKTSAELV----LPIK 967
T +++ + W+ + GYK++Y SQN + + +V L
Sbjct: 1712 PLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTSH 1771
Query: 968 EDYIIEVKATTDGGDGTSSE 987
Y++ + A GDG S+
Sbjct: 1772 TKYLVSISAFNAAGDGPKSD 1791
Score = 79.3 bits (194), Expect = 2e-14
Identities = 77/295 (26%), Positives = 129/295 (43%), Gaps = 14/295 (4%)
Query: 659 TATVVELN---PWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRS 715
T+T+ EL + YE + A N IG S P E V EA P + P V + S
Sbjct: 1658 TSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVE-VFVGEAAPAMAPQNVQVTPLTAS 1716
Query: 716 ELVITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYE 775
+L +TWDP P E QNG GY + + + + P V R +++ ++ Y
Sbjct: 1717 QLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVL-FLPEPVVRLKNLTSHTKYL 1775
Query: 776 VKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHL 835
V + +N G+GP S + + P APS ++ + ++S+ + VSW +NG L
Sbjct: 1776 VSISAFNAAGDGPKSDPQQGRTHQAAPG-APSFLAFSEITSTTLNVSWGEP--AAANGIL 1832
Query: 836 LGYEVRYWNGGGKEESSS--KMKVAGN-ETSARLRGLKSNLAYYTAVRAYNSAGAGPFSA 892
GY V Y + S ++V GN + ++R L + Y+ V+A A
Sbjct: 1833 QGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTITYGPELQA 1892
Query: 893 TVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQ 947
+ + P P +V+ + +++ L W + ++ TGY + R S +
Sbjct: 1893 NITAGPAEGSPGS-PRDVLVTKSASELTLQW--TEGHSGDTPTTGYVIEARPSDE 1944
Score = 60.5 bits (145), Expect = 8e-09
Identities = 39/106 (36%), Positives = 53/106 (50%), Gaps = 4/106 (3%)
Query: 596 GSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQT-VTTVPEVID 654
GSPG P +V V + + + L W EG +P Y I+AR W V +P
Sbjct: 1901 GSPGSPRDVLVTK-SASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPR--S 1957
Query: 655 GKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVP 700
++T ++ +L V YEFRVVA N+ G GEPS PS V + P
Sbjct: 1958 ATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAP 2003
Score = 45.8 bits (107), Expect = 2e-04
Identities = 54/217 (24%), Positives = 74/217 (34%), Gaps = 21/217 (9%)
Query: 595 RGSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVID 654
+ +PG P + EIT TT +SW E + + Y + V + EV
Sbjct: 1799 QAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRG 1858
Query: 655 GKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSR 714
V +L V Y FRV A G E + G GS
Sbjct: 1859 NWQRWLKVRDLTKGVTYFFRVQARTITYG------------PELQANITAGPAEGSPGSP 1906
Query: 715 SELVITWDPVPEELQNGEGF-------GYVVAFRPLGVTTWIQTVVTSP-DTPRYVFRNE 766
++++T LQ EG GYV+ RP W V P Y +
Sbjct: 1907 RDVLVTKSASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLD 1966
Query: 767 SIVPYSPYEVKVGVYNNKGEG-PFSPVTTVFSAEEEP 802
+ YE +V N G G P +P T V + E P
Sbjct: 1967 KLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAP 2003
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 242 bits (618), Expect = 1e-63
Identities = 252/1024 (24%), Positives = 416/1024 (40%), Gaps = 90/1024 (8%)
Query: 25 GPVFIKEPSNSIFPV----GSEDKKITLHCEARGNPSPHYRWQLNGSDIDMSMEHRYK-L 79
G +++K+P + S +++L C G W NG ++ R +
Sbjct: 306 GRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGI 365
Query: 80 NGGNLVVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVS---VRE 136
N NL++ + ++ D G YQCF +S + +Q LE+ K+ S S V
Sbjct: 366 NHENLIMDHMVKS-DGGAYQCFVRKDK---LSAQDYVQVV-LEDGTPKIISAFSEKVVSP 420
Query: 137 GQGVVLLCG----PPPHSGELSYAWIFNEYPSFVEEDSR--RFVSQE---TGHLYISKVE 187
+ V L+C P P + W ++ P R + ++ E +L IS +
Sbjct: 421 AEPVSLMCNVKGTPLP-----TITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQ 475
Query: 188 PSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFP------ETLPAAK 241
D G Y C + S GV+ Y+ +I V+ P + + A
Sbjct: 476 VRDGGVYRCTANN-----------------SAGVV-LYQARINVRGPASIRPMKNITAIA 517
Query: 242 GSTVKLECFALGNPIPQINW-RRSDGLPFSSKIKLRKFSGVLEIPNFQQE-DAGSYECIA 299
G + C +G P I W + S+ LPF+ + + +G L++ + Q+E D G Y C
Sbjct: 518 GRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNV 577
Query: 300 ENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRA-SGKPKPSYRWLKNGAAL 358
+ ++ P ++Q + ++ ++ C SG + W K+G +
Sbjct: 578 LVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPI 637
Query: 359 VLEERTQIEN----GALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNP 414
I+N +L ISNLS+ +G + CIA N+ V ++L +V P F P
Sbjct: 638 PGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQL-IVRVPPKFVVQP 696
Query: 415 MKKLVQVQVGSLVSLDCKPRASPRALSSWK--KGD-----VSVQEHERISLLNDGGLKIA 467
+ G V L+C P WK KG + + RI +L++G L I
Sbjct: 697 RDQ--DGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIK 754
Query: 468 NVTKADAGTYTCMAENQFGK-ANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHD 526
+V + D+G Y C N G + + +L V P IT P+ + G+ + C +
Sbjct: 755 HVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGE 814
Query: 527 PLLDIIFTW-----YFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQT 581
II W N +A + ++VG L I + SG + C
Sbjct: 815 K--PIIVRWEKEDRIINPEMARYLVST---KEVGEEVISTLQILPTVREDSGFFSCHAIN 869
Query: 582 GVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSV 641
L V+ P PPE +++ ++ T L W G D +SP+ Y I+ + S
Sbjct: 870 SYGEDRGIIQLTVQEPPDPPE-IEIKDVKARTITLRWTMGFDGNSPITGYDIECKNK-SD 927
Query: 642 GWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPE 701
W + +V + ++AT+++++P Y R+ A N+IG EPS + +EA P+
Sbjct: 928 SWDSAQRTKDV-SPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPS-NELTITADEAAPD 985
Query: 702 VPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTP-- 759
PP EV+ S + +TW + LQNG GY + +R Q + S DT
Sbjct: 986 GPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGD 1045
Query: 760 RYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEI 819
V+ +++ ++ Y + V N G GP S + E+ P+ P V A + S I
Sbjct: 1046 SEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESI 1105
Query: 820 EVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAV 879
+SW+T+ + NG L G+ V YW E + + S L GL+ Y V
Sbjct: 1106 SISWSTLSKEALNGILQGFRVIYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQV 1165
Query: 880 RAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYK 939
A+ AG G S + TK+ P P G A+ + V ++W + ++ + Y
Sbjct: 1166 LAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSW--LPPLKLNGIIRKYT 1223
Query: 940 VFYRTSSQNNVQVLNTNKTSAELVLP---IKEDYIIEVKATTDGGDGTSSEQIRIPRITS 996
VF + + S +P Y + V A T G G SSE I + +
Sbjct: 1224 VFCSHPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPLAK 1283
Query: 997 MDAR 1000
AR
Sbjct: 1284 APAR 1287
Score = 197 bits (500), Expect = 6e-50
Identities = 246/1035 (23%), Positives = 418/1035 (40%), Gaps = 141/1035 (13%)
Query: 27 VFIKEPSNSIFPV--GSEDKK------ITLHCEARGNPSPHYRWQLNGSDIDMSMEHRYK 78
+F+ +P+NS + G + +K + L C+A G+P P YRW + +++S +
Sbjct: 215 LFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKT 274
Query: 79 LNGGNLVVINPNRNWDTGTYQCFATNSLGT--IVSREAKLQFAYLENFKTKMRSTVSVRE 136
+ G + I P+ D+G+Y C +N GT ++ R Y+ K +++T+S R+
Sbjct: 275 VTGLLIENIRPS---DSGSYVCEVSNRYGTAKVIGR------LYV---KQPLKATISPRK 322
Query: 137 -----GQGVVLLCG-PPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSD 190
G V L C ELS+ + + R +L + + SD
Sbjct: 323 VKSSVGSQVSLSCSVTGTEDQELSW---YRNGEILNPGKNVRITGINHENLIMDHMVKSD 379
Query: 191 VGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECF 250
G Y C V ++ V+ DG PKI F E + + V L C
Sbjct: 380 GGAYQC----FVRKDKLSAQDYVQVVLEDGT-----PKIISAFSEKV-VSPAEPVSLMCN 429
Query: 251 ALGNPIPQINWRRSD------GLPFSSKIKLRKFSGV--LEIPNFQQEDAGSYECIAENS 302
G P+P I W D G S++ + + V L I + Q D G Y C A NS
Sbjct: 430 VKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNS 489
Query: 303 RGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEE 362
G + + R+ P ++ +K++ Y CR G P S +W KN L
Sbjct: 490 AGVVLYQARINVRG-PASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNH 548
Query: 363 RTQI--ENGALTISNL-SVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLV 419
R NG L +S++ D G + C + L +S + V P F + P +
Sbjct: 549 RQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQL-STSQSVHVTVKVPPFIQ-PF-EFP 605
Query: 420 QVQVGSLVSLDCKPRASPRALS-SWKKGDVSVQEHERISLLN---DGGLKIANVTKADAG 475
+ +G V + C + ++ +W+K + +++ N L+I+N++ G
Sbjct: 606 RFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNG 665
Query: 476 TYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTW 535
YTC+A N+ + L+V P + + P + D G++VIL C + P+ I++ +
Sbjct: 666 NYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKF 725
Query: 536 YFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDS-VSSAADLIV 594
+ F+ + ++ S+G L+I+++ + SG Y+C V V + VS + L V
Sbjct: 726 SKGAGVPQFQPIALN-GRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTV 784
Query: 595 RGSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVID 654
+ P + T Q KE +S + P V W+ +
Sbjct: 785 K----IPAMITSYPNTTLATQGQKKE--------MSCTAHGEKPIIVRWEKEDRI----- 827
Query: 655 GKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSE-------V 707
+NP E +V++ ++G E + T + +P V +
Sbjct: 828 ----------INP--EMARYLVSTKEVG-------EEVISTLQILPTVREDSGFFSCHAI 868
Query: 708 NGGGGSRS--ELVITWDPVPEELQ-------------------NGEGFGYVVAFRPLGVT 746
N G R +L + P P E++ N GY + +
Sbjct: 869 NSYGEDRGIIQLTVQEPPDPPEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKS-D 927
Query: 747 TWIQTVVTSPDTPRYVFRNESIV---PYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPT 803
+W T +P+ + +I+ P S Y +++ N G+ S T+ + E P
Sbjct: 928 SWDSAQRTKDVSPQ--LNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPD 985
Query: 804 VAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEV---RYWNGGGKEESSSKMKVAGN 860
P +V +SS I V+W L NG + GY++ Y GG + + + +G+
Sbjct: 986 GPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGD 1045
Query: 861 ETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTK-V 919
L L Y V+A N AG GP S + TT + PS PP NV AT + +
Sbjct: 1046 SEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESI 1105
Query: 920 LLNWEQVKAMENESEVTGYKVFYRTSSQN----NVQVLNTNKTSAEL-VLPIKEDYIIEV 974
++W + + G++V Y + + ++ + T + S EL L +Y I+V
Sbjct: 1106 SISWSTLSKEALNGILQGFRVIYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQV 1165
Query: 975 KATTDGGDGTSSEQI 989
A T GDG SEQI
Sbjct: 1166 LAFTRAGDGVRSEQI 1180
Score = 112 bits (279), Expect = 2e-24
Identities = 135/550 (24%), Positives = 208/550 (37%), Gaps = 38/550 (6%)
Query: 50 CEARGNPSPHYRWQL-NGSDI-DMSMEHRYKLNGGNLVVINPNRNWDT----GTYQCFAT 103
C A G P RW L G +I D+ NG + P ++ T TY C A
Sbjct: 46 CPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAE 105
Query: 104 NSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYP 163
N G I S++ ++ E + ++ ++R G V C P S E + E
Sbjct: 106 NPSGKIRSQDVHIKAVLREPYTVRVEDQKTMR-GNVAVFKC-IIPSSVEAYITVVSWEKD 163
Query: 164 SFVEEDSRRFVSQETGHLYISKVEPSD-VGNYTCVVTSMVTNARVLGSPTPLVLRSDGVM 222
+ RF+ TG LYI V+ D + NY C+ T + L +
Sbjct: 164 TVSLVSGSRFLITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDP--- 220
Query: 223 GEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVL 282
P I F + A G V+L C ALG+P P W + D +P + +K L
Sbjct: 221 ANSAPSILDGF-DHRKAMAGQRVELPCKALGHPEPDYRWLK-DNMPLELSGRFQKTVTGL 278
Query: 283 EIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLI-KDVEIAVEDSLYWECRA 341
I N + D+GSY C N G GRL Y +P + + V+ +V + C
Sbjct: 279 LIENIRPSDSGSYVCEVSNRYGTAKVIGRL-YVKQPLKATISPRKVKSSVGSQVSLSCSV 337
Query: 342 SGKPKPSYRWLKNGAALVLEER---TQIENGALTISNLSVTDSGMFQCIAENKHGLVYSS 398
+G W +NG L + T I + L + ++ +D G +QC
Sbjct: 338 TGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDY 397
Query: 399 AELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWKKGDVSVQE---HER 455
++ + P +K+ V VSL C + +P +W D + + H
Sbjct: 398 VQVVLEDGTPKIISAFSEKV--VSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRI 455
Query: 456 ISLLNDGG-----LKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMD 510
++ G L I++ D G Y C A N G + V P I N+
Sbjct: 456 SQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIR-PMKNIT 514
Query: 511 VSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLK 570
G + C+V P I WY N L F + +V ++G L + ++Q +
Sbjct: 515 AIAGRDTYIHCRVIGYPYYSI--KWYKNSNLLPF-----NHRQVAFENNGTLKLSDVQKE 567
Query: 571 -HSGKYVCMV 579
G+Y C V
Sbjct: 568 VDEGEYTCNV 577
Score = 72.8 bits (177), Expect = 2e-12
Identities = 85/374 (22%), Positives = 149/374 (39%), Gaps = 36/374 (9%)
Query: 249 CFALGNPIPQINWRRSDGLPFSSKIKLRKF--SGVLEIPNFQQEDAGS------YECIAE 300
C A G P + W + G +R +G L+I F + Y C AE
Sbjct: 46 CPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAE 105
Query: 301 NSRGKNVARG-RLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYR---WLKNGA 356
N GK ++ + + + ++D + + ++C + W K+
Sbjct: 106 NPSGKIRSQDVHIKAVLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTV 165
Query: 357 ALVLEERTQIEN-GALTISNLSVTDSGM-FQCIAENKHGLVYSSAELKVVASAPDFSKNP 414
+LV R I + GAL I ++ D ++CI +++ + E + SA F +P
Sbjct: 166 SLVSGSRFLITSTGALYIKDVQNEDGLYNYRCITRHRY-----TGETRQSNSARLFVSDP 220
Query: 415 MKKLVQV---------QVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLK 465
+ G V L CK P W K ++ ++ R G L
Sbjct: 221 ANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTG-LL 279
Query: 466 IANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQH 525
I N+ +D+G+Y C N++G A L V +P + T++P + SVG V L C V
Sbjct: 280 IENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTG 339
Query: 526 DPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDS 585
D +WY NG + + K+ ++ G + +L++ ++ G Y C V+ S
Sbjct: 340 TE--DQELSWYRNGEILNPGKN----VRITGINHENLIMDHMVKSDGGAYQCFVRKDKLS 393
Query: 586 VSSAADLIVR-GSP 598
+++ G+P
Sbjct: 394 AQDYVQVVLEDGTP 407
Score = 55.8 bits (133), Expect = 2e-07
Identities = 68/328 (20%), Positives = 131/328 (39%), Gaps = 26/328 (7%)
Query: 465 KIANVTKADAGTYTCMAENQFGKANGTTHLVVTE----PTRITLAPSNMDVSVGESVILP 520
+I N+++ + +A G+ N + + V P RI + + ++LP
Sbjct: 1247 RIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVLP 1306
Query: 521 CQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQ 580
C+ DP + + NG + DG + S+G +IR ++ + SG Y C+
Sbjct: 1307 CKAVGDPSPAVKWMKDSNGTPSLVTIDG----RRSIFSNGSFIIRTVKAEDSGYYSCIAN 1362
Query: 581 TGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFS 640
S +L V+ P P + V + T ++ LSW G + S + Y +Q S
Sbjct: 1363 NNWGSDEIILNLQVQVPPDQP-RLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNS 1421
Query: 641 VGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVP 700
W + P +++ ++ W Y+F + A N +G G S E +T P
Sbjct: 1422 EQWGSFPISP---SERSYRLENLKCGTW--YKFTLTAQNGVGPGRISEIIE-AKTLGKEP 1475
Query: 701 EVPPSEVNGGGGSRSEL---VITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPD 757
+ + + + + +I W+ + + + + +RP G T W TS
Sbjct: 1476 QFSKEQELFASINTTRVRLNLIGWNDGGCPITS-----FTLEYRPFGTTVWTTAQRTSLS 1530
Query: 758 TPRYVFRNESIVPYSPYEVKVGVYNNKG 785
++ + + YE+++ V N+ G
Sbjct: 1531 KSYILY---DLQEATWYELQMRVCNSAG 1555
Score = 42.4 bits (98), Expect = 0.002
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 5/60 (8%)
Query: 339 CRASGKPKPSYRWLK--NGAALVLE---ERTQIENGALTISNLSVTDSGMFQCIAENKHG 393
C+A G P P+ +W+K NG ++ R+ NG+ I + DSG + CIA N G
Sbjct: 1307 CKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWG 1366
Score = 40.0 bits (92), Expect = 0.011
Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Query: 44 KKITLHCEARGNPSPHYRW--QLNGSDIDMSMEHRYKLNGGNLVVINPNRNWDTGTYQCF 101
K I L C+A G+PSP +W NG+ ++++ R + +I + D+G Y C
Sbjct: 1301 KDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCI 1360
Query: 102 ATNSLGT 108
A N+ G+
Sbjct: 1361 ANNNWGS 1367
Score = 39.3 bits (90), Expect = 0.019
Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 4/66 (6%)
Query: 245 VKLECFALGNPIPQINWRR-SDGLPFSSKIKLRKF---SGVLEIPNFQQEDAGSYECIAE 300
+ L C A+G+P P + W + S+G P I R+ +G I + ED+G Y CIA
Sbjct: 1303 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIAN 1362
Query: 301 NSRGKN 306
N+ G +
Sbjct: 1363 NNWGSD 1368
Score = 36.6 bits (83), Expect = 0.12
Identities = 58/272 (21%), Positives = 96/272 (35%), Gaps = 41/272 (15%)
Query: 427 VSLDCKPRASPRALSSWKKGDVS----VQEHERISLLNDGGLKIANVTKADAGTYTCMAE 482
+ L CK P W K V R S+ ++G I V D+G Y+C+A
Sbjct: 1303 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIAN 1362
Query: 483 NQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWY------ 536
N +G +L V P P ++V ++ I +W
Sbjct: 1363 NNWGSDEIILNLQVQVP------PDQPRLTVSKTT----------SSSITLSWLPGDNGG 1406
Query: 537 --FNGALADFKKDGSHFEKVG----GSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAA 590
G + + +D S E+ G S + N++ K+ Q GV +
Sbjct: 1407 SSIRGYILQYSEDNS--EQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISE 1464
Query: 591 DLIVRGSPGPPENVKVDE----ITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTV 646
+ + P+ K E I T +L+ D P+ S++++ R PF G
Sbjct: 1465 IIEAKTLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYR-PF--GTTVW 1521
Query: 647 TTVPEVIDGKTHTATVVELNPWVEYEFRVVAS 678
TT K++ ++ W E + RV S
Sbjct: 1522 TTAQRTSLSKSYILYDLQEATWYELQMRVCNS 1553
>gi|237858682 neurofascin isoform 6 precursor [Homo sapiens]
Length = 613
Score = 226 bits (577), Expect = 7e-59
Identities = 172/618 (27%), Positives = 267/618 (43%), Gaps = 43/618 (6%)
Query: 4 PWKQLILLSFIGCLGGEL-----LLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSP 58
PW L + LGG + L Q P K+ + V D I + CEA+GNP+P
Sbjct: 8 PWVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHI-VDPRDN-ILIECEAKGNPAP 65
Query: 59 HYRWQLNGSDIDMSMEHRYKLN--GGNLVV---INPNRNWDTGTYQCFATNSLGTIVSRE 113
+ W N +++ + R + G LV+ G YQCFA N GT +S
Sbjct: 66 SFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNR 125
Query: 114 AKLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRF 173
+LQ + + + V V+EG + L C PPP W+ + ++ +R
Sbjct: 126 IRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD--KRV 183
Query: 174 VSQETGHLYISKVEPSDVG-NYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQ 232
G LY S V D+ +Y+C T+ + P L+ G E
Sbjct: 184 SQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHT--IQQKNPFTLKVLTTRGVAERTPSFM 241
Query: 233 FPETLPAA----KGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQ 288
+P+ ++ +G + LEC A G P P I W + G S K K F+ L I N
Sbjct: 242 YPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVS 301
Query: 289 QEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPS 348
+ED+G Y C+A N G + A P+W+ K++ +A + CRA+G PKP+
Sbjct: 302 EEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPT 361
Query: 349 YRWLKNGAALVL---EERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVA 405
+W+ NG L ++ + + ++ ++QC N+HG + ++A + V+
Sbjct: 362 VQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVL- 420
Query: 406 SAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSW-KKGDVSVQEHERISLLNDGGL 464
P +P +L++V + + LDC SP W K G S + + +G L
Sbjct: 421 DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSL 480
Query: 465 KIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQ 524
+I + K D G YTC+A N GKA L V +PTRI P + G +V L C+V+
Sbjct: 481 EIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVK 540
Query: 525 HDPLLDIIFTWYFNGALADFKKD-----GSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMV 579
HDP L + +W K D G+ +K S L I + + G Y C+
Sbjct: 541 HDPSLKLTVSW--------LKDDEPLYIGNRMKKEDDS----LTIFGVAERDQGSYTCVA 588
Query: 580 QTGVDSVSSAADLIVRGS 597
T +D + A L V G+
Sbjct: 589 STELDQDLAKAYLTVLGN 606
Score = 81.6 bits (200), Expect = 3e-15
Identities = 81/301 (26%), Positives = 128/301 (42%), Gaps = 33/301 (10%)
Query: 322 QLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIE----NGALTISNLS 377
Q KD + D++ EC A G P PS+ W +N + + ++ +G L I S
Sbjct: 40 QSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRS 99
Query: 378 ----VTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKP 433
G +QC A NK G S+ V+ +P + K + +V VQ G+ ++L C P
Sbjct: 100 GGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVV-VQEGAPLTLQCNP 158
Query: 434 RAS-PRALSSWKKGDVS-VQEHERISLLNDGGLKIANVTKADAGT-YTCMAENQFG---- 486
P + W + + + +R+S ++G L +NV D T Y+C A F
Sbjct: 159 PPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQ 218
Query: 487 KANGTTHLVVT-----EPTRITLAP----SNMDVSVGESVILPCQVQHDPLLDIIFTWYF 537
+ N T V+T E T + P S+ V G ++L C P DI WY
Sbjct: 219 QKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDI--AWYK 276
Query: 538 NGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGS 597
G D D + FE + L I N+ + SG+Y C+ + S+ + V+ +
Sbjct: 277 KGG--DLPSDKAKFENFNKA----LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAA 330
Query: 598 P 598
P
Sbjct: 331 P 331
Score = 79.0 bits (193), Expect = 2e-14
Identities = 88/374 (23%), Positives = 155/374 (41%), Gaps = 34/374 (9%)
Query: 46 ITLHCEARGNPSPHYRWQLNGSDIDMSMEHRYKLNGGNLVVINPNRNWDTGTYQCFATNS 105
+ L C A G P+P W G D+ S + +++ L + N + D+G Y C A+N
Sbjct: 258 LLLECIASGVPTPDIAWYKKGGDLP-SDKAKFENFNKALRITNVSEE-DSGEYFCLASNK 315
Query: 106 LGTI---VSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLC----GPPPHSGELSYAWI 158
+G+I +S K +L+ K + + G+ L+C P P + W+
Sbjct: 316 MGSIRHTISVRVKAAPYWLDEPKNLI-----LAPGEDGRLVCRANGNPKP-----TVQWM 365
Query: 159 FNEYP-SFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLR 217
N P + R V+ +T + + S Y C ++ + +L + VL
Sbjct: 366 VNGEPLQSAPPNPNREVAGDT--IIFRDTQISSRAVYQCNTSN--EHGYLLANAFVSVL- 420
Query: 218 SDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINW-RRSDGLPFSSKIKLR 276
+ P++ + + + +L+C G+PIP + W + G
Sbjct: 421 ------DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHV 474
Query: 277 KFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLY 336
+G LEI ++ED G Y C+A N GK + RL ++ +D ++
Sbjct: 475 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 534
Query: 337 WECRASGKP--KPSYRWLKNGAALVLEERTQIENGALTISNLSVTDSGMFQCIAENKHGL 394
ECR P K + WLK+ L + R + E+ +LTI ++ D G + C+A +
Sbjct: 535 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQ 594
Query: 395 VYSSAELKVVASAP 408
+ A L V+ + P
Sbjct: 595 DLAKAYLTVLGNCP 608
>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
sapiens]
Length = 2113
Score = 225 bits (574), Expect = 1e-58
Identities = 237/995 (23%), Positives = 398/995 (40%), Gaps = 93/995 (9%)
Query: 46 ITLHCEARGNPSPHYRWQLNGSDI--DMSMEHRYKLNGGNLVVINPNRNWDTGTYQCFAT 103
+ L C G+P RW N + D ++ R L+ L++ + ++ +G YQCFAT
Sbjct: 392 VILSCALTGSPEFTIRWYRNTELVLPDEAISIR-GLSNETLLITSAQKS-HSGAYQCFAT 449
Query: 104 NSLGTIVSREAKLQFAYLENFKTKMRSTVS---VREGQGVVLLCG----PPPHSGELSYA 156
T LE+ ++ S+ S V G+ L+C PPP +
Sbjct: 450 RKAQTAQD----FAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPP-----TVT 500
Query: 157 WIFNEYPSFVEEDSRRFVSQET-------GHLYISKVEPSDVGNYTCVVTSMVTNARVLG 209
W ++ P + D +Q T H+ ++ + D G Y C ++V +A
Sbjct: 501 WALDDEP--IVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSA---- 554
Query: 210 SPTPLVLRSDGVMGEYEPKIEVQFPETLPAAK------GSTVKLECFALGNPIPQINWRR 263
EY+ +I V+ P ++ A + G + C +G P I W +
Sbjct: 555 --------------EYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYK 600
Query: 264 SDGLPFSSKIKLRKFSGVLEIPNFQQE-DAGSYECIAENSRGKNVARGRLTYYAKPHWVQ 322
L + ++ +G L++ + Q+ D G Y C ++++ P +Q
Sbjct: 601 DALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQ 660
Query: 323 LIKDVEIAVEDSLYWECRASGKPKP-SYRWLKNGAALVLEERTQIEN----GALTISNLS 377
+ ++ LY C S P W K+G ++ IE+ +L IS++S
Sbjct: 661 PFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVS 720
Query: 378 VTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASP 437
+ +G + CIA N V +L +V P F P + G L+C P
Sbjct: 721 LKHNGNYTCIASNAAATVSRERQL-IVRVPPRFVVQPNNQ--DGIYGKAGVLNCSVDGYP 777
Query: 438 RALSSWK--KGDVSVQEHE------RISLLNDGGLKIANVTKADAGTYTCMAENQFGK-A 488
WK KG + Q++ RI +L + L I +V + D G Y C A N G
Sbjct: 778 PPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDI 837
Query: 489 NGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDG 548
+ + L V P IT P+ G + L C + + II W + D D
Sbjct: 838 SKSMFLTVKIPAMITSHPNTTIAIKGHAKELNCTARGER--PIIIRWEKGDTVID--PDR 893
Query: 549 SHFEKVGGSSSGDLMIRNIQLKHSGK-----YVCMVQTGVDSVSSAADLIVRGSPGPPEN 603
+ +GD ++ ++LK + + + C L V+ P PPE
Sbjct: 894 VMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPE- 952
Query: 604 VKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVV 663
+++ E+ + L W + D +S + + I+ + S W + I + A +V
Sbjct: 953 LEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNK-SDSWDFKQSTRN-ISPTINQANIV 1010
Query: 664 ELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDP 723
+L+P Y R+ + NKIG EPS + TEEA P+ PP +V + + +TW
Sbjct: 1011 DLHPASVYSIRMYSFNKIGRSEPS-KELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKA 1069
Query: 724 VPEELQNGEGFGYVVAFRPL--GVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVY 781
+ELQNG GY + +R G V V+ +++ ++ Y V V +
Sbjct: 1070 PKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAF 1129
Query: 782 NNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVR 841
N G GP S + E+ P+ P V A S++S +SW+ P NG L GY V
Sbjct: 1130 NRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVI 1189
Query: 842 YWNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKT 901
+W+ E + LRG++ Y V AY AG G S+ + + TK+
Sbjct: 1190 FWSLYVDGEWGEMQNITTTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKED 1249
Query: 902 PPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSAE 961
P P G ++ + V+++W + + + Y +F + + +
Sbjct: 1250 VPGPPAGIKAVPSSASSVVVSW--LPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSPEQ 1307
Query: 962 LVLPIK-----EDYIIEVKATTDGGDGTSSEQIRI 991
L I + Y++ V A T G G SSE++ I
Sbjct: 1308 LFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTI 1342
Score = 160 bits (405), Expect = 6e-39
Identities = 220/930 (23%), Positives = 366/930 (39%), Gaps = 121/930 (13%)
Query: 44 KKITLHCEARGNPSPHYRWQLNGSDIDMSMEHR---YKLNGGNLV----VINPNRNWDTG 96
++ +L C A+G P P W L+ I HR Y ++ G + V P D G
Sbjct: 483 EQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIR-DGG 541
Query: 97 TYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLC---GPPPHSGEL 153
Y+C A N +G+ +A++ + + MR+ +V G+ ++ C G P +
Sbjct: 542 VYRCTARNLVGS-AEYQARINVRGPPSIRA-MRNITAV-AGRDTLINCRVIGYPYY---- 594
Query: 154 SYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPS-DVGNYTCVVTSMVTNARVLGSPT 212
S W + + + D+ R V E G L ++ V+ D G Y C VL P
Sbjct: 595 SIKWYKD---ALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLC---------SVLIQPQ 642
Query: 213 PLVLRSDGVMGEYEPKIE-VQFPETLPAAKGSTVKLECFALGNPIP-QINWRRSDGLPFS 270
+ +S V + P I+ +FP PA+ G + + C +P +I WR+ + S
Sbjct: 643 LSISQSVHVAVKVPPLIQPFEFP---PASIGQLLYIPCVVSSGDMPIRITWRKDGQVIIS 699
Query: 271 SK---IKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDV 327
I+ ++F L+I + + G+Y CIA N+ +L P +V V
Sbjct: 700 GSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFV-----V 754
Query: 328 EIAVEDSLYWE-----CRASGKPKPSYRWLKNGAA--------LVLEERTQI-ENGALTI 373
+ +D +Y + C G P P W + + L R QI N +L I
Sbjct: 755 QPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLI 814
Query: 374 SNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKP 433
++ D G + C A N G S + V + +P + G L+C
Sbjct: 815 RHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTTI--AIKGHAKELNCTA 872
Query: 434 RASPRALSSWKKGDVSVQEHERIS----LLNDGG------LKIANVTKADAGTYTCMAEN 483
R + W+KGD +V + +R+ D G LK+ + D+ ++C A N
Sbjct: 873 RGERPIIIRWEKGD-TVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHAIN 931
Query: 484 QFGKANGTTHLVVTEPTRITLAPSNMDVSV---------------GESVILPCQVQHDPL 528
+G+ G L V EP P +++ G S+I +++
Sbjct: 932 SYGEDRGLIQLTVQEPP----DPPELEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNK 987
Query: 529 LDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSS 588
D +W F + + + V + IR G+ + + + +
Sbjct: 988 SD---SWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEA 1044
Query: 589 AADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKD--NHSPVISYSIQAR--TPFSVGWQ 644
A D GPP +V + +T + Q++WK K + + Y I R +P S G
Sbjct: 1045 APD-------GPPMDVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQY 1097
Query: 645 TVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPP 704
++ + D + + T+ L + +Y V A N+ G G PS T E VP PP
Sbjct: 1098 SIVEMKATGDSEVY--TLDNLKKFAQYGVVVQAFNRAGTG-PSSSEINATTLEDVPSQPP 1154
Query: 705 SEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGVT-TW--IQTVVTSPDTPRY 761
V + VI+W P NG GY V F L V W +Q + T+ R
Sbjct: 1155 ENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTT----RE 1210
Query: 762 VFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEV 821
+ ++ Y V+V Y G+G S V + + E+ P P+ + A S+S + V
Sbjct: 1211 RVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPG-PPAGIKAVPSSASSVVV 1269
Query: 822 SWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRA 881
SW +P NG + Y + + G + + S+ + + + R+ L Y V A
Sbjct: 1270 SW--LPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAA 1327
Query: 882 YNSAGAGPFSATVNVTTKKTPPSQPPGNVV 911
SAG G S V + P + P ++
Sbjct: 1328 VTSAGRGNSSEKVTI----EPAGKAPAKII 1353
Score = 132 bits (331), Expect = 2e-30
Identities = 207/948 (21%), Positives = 348/948 (36%), Gaps = 105/948 (11%)
Query: 46 ITLHCEARGNPSPHYRWQLNGSDIDMSMEHRYKLNGGNLVVINP------NRNWDTGTYQ 99
+ + C A G+PS RW L D + H ++ + + P N Y
Sbjct: 103 VVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDNDYF 162
Query: 100 CFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIF 159
C A N+ G I S +++ + E + ++ S+R G V C P E +
Sbjct: 163 CTAENAAGKIRSPNIRVKAVFREPYTVRVEDQRSMR-GNVAVFKCLIPSSVQEYVSVVSW 221
Query: 160 NEYPSFVEEDSRRFVSQETGHLYISKVEPSD-VGNYTCVVTSMVTNARVLGSPTPLVLRS 218
+ + + R F++ G LYIS V+ D + Y C+ + + L +
Sbjct: 222 EKDTVSIIPEHRFFITYHGG-LYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTD 280
Query: 219 DGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKF 278
E P I F + G TV+L C A G PIP I W + DG P + + K
Sbjct: 281 PA---ESIPTILDGF-HSQEVWAGHTVELPCTASGYPIPAIRWLK-DGRPLPADSRWTKR 335
Query: 279 SGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWE 338
L I + + ED+G+Y C N+ G A G L H K ++ + ++
Sbjct: 336 ITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILS 395
Query: 339 CRASGKPKPSYRWLKNGAALVLEERTQI---ENGALTISNLSVTDSGMFQCIAENKHGLV 395
C +G P+ + RW +N ++ +E I N L I++ + SG +QC A K
Sbjct: 396 CALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKAQTA 455
Query: 396 YSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWKKGD---VSVQE 452
A + + P + +K+ V G SL C + +P +W D V
Sbjct: 456 QDFAIIALEDGTPRIVSSFSEKV--VNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGS 513
Query: 453 HERISLLNDGGLKIA--NVTK---ADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPS 507
H G I+ NVT D G Y C A N G A + V P I A
Sbjct: 514 HRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIR-AMR 572
Query: 508 NMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNI 567
N+ G ++ C+V P I WY + L FE +G L + ++
Sbjct: 573 NITAVAGRDTLINCRVIGYPYYSI--KWYKDALLLPDNHRQVVFE------NGTLKLTDV 624
Query: 568 QL-KHSGKYVCMVQTGVD-SVSSAADLIVRGSP------GPPENVKVDEITDTTAQLSWK 619
Q G+Y+C V S+S + + V+ P PP ++
Sbjct: 625 QKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASI--------------- 669
Query: 620 EGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASN 679
G+ + P + S P + W+ V +I G + +E ++ S
Sbjct: 670 -GQLLYIPCVVSS--GDMPIRITWRKDGQV--IISG---SGVTIESKEFMSSLQISSVSL 721
Query: 680 KIGGGEPSLPSEKV----RTEEAVPEVPP---------SEVNGGGGSRSELVITWDPVPE 726
K G + S R + + VPP + G G + V + P
Sbjct: 722 KHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKV 781
Query: 727 ELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGE 786
++ +G G + P+ +T IQ + S R+V E + Y + GV + +
Sbjct: 782 MWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVL--EEDIGYYLCQASNGVGTDISK 839
Query: 787 GPFSPV--TTVFSAEEEPTVA----PSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEV 840
F V + ++ T+A +++ + I + W + ++ Y +
Sbjct: 840 SMFLTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAI 899
Query: 841 RYWNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKK 900
+ G + S+ K+K A S + + A NS G + +T ++
Sbjct: 900 ATKDNGDEVVSTLKLKPADRGDSV-----------FFSCHAINSYGED--RGLIQLTVQE 946
Query: 901 TPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQN 948
P PP + + L W Q + S +TG+ + Y+ S +
Sbjct: 947 --PPDPPELEIREVKARSMNLRWTQ--RFDGNSIITGFDIEYKNKSDS 990
Score = 37.7 bits (86), Expect = 0.056
Identities = 28/111 (25%), Positives = 46/111 (41%), Gaps = 4/111 (3%)
Query: 231 VQFPETLPAAKGSTVKLECFALGNPIPQINWRR---SDGLPFS-SKIKLRKFSGVLEIPN 286
+ F T+ V+L C ++G+P P + W + +P S +L +G L +
Sbjct: 1353 ISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRA 1412
Query: 287 FQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYW 337
+ ED+G Y C A N+ G + L P +L A +L W
Sbjct: 1413 VKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPDQPRLTVSKTSASSITLTW 1463
Score = 37.7 bits (86), Expect = 0.056
Identities = 19/66 (28%), Positives = 35/66 (53%), Gaps = 2/66 (3%)
Query: 44 KKITLHCEARGNPSPHYRWQLNGSD--IDMSMEHRYKLNGGNLVVINPNRNWDTGTYQCF 101
K + L C + G+P+P +W + D I +SM+ ++ +++ + D+G Y C
Sbjct: 1365 KDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCT 1424
Query: 102 ATNSLG 107
ATN+ G
Sbjct: 1425 ATNTGG 1430
Score = 36.2 bits (82), Expect = 0.16
Identities = 46/221 (20%), Positives = 89/221 (40%), Gaps = 41/221 (18%)
Query: 701 EVPPSE--VNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDT 758
+VPP + + S S + +TW +P + G+V+ + W ++S +
Sbjct: 1441 QVPPDQPRLTVSKTSASSITLTW--IPGDNGGSSIRGFVLQYSVDNSEEWKDVFISSSER 1498
Query: 759 PRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSE 818
F+ +S+ + Y+VK+ N+ G G S + + EP+ + Q ++S+
Sbjct: 1499 S---FKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREPSFSKDQHLFTHINSTH 1555
Query: 819 IEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNETSARLRGLKSNLA---- 874
++ ++ WN GG ++ ++ T A +GL++N +
Sbjct: 1556 ARLN-----------------LQGWNNGGCPITAIVLEYRPKGTWA-WQGLRANSSGEVF 1597
Query: 875 ---------YYTAVRAYNSAGAGPFS---ATVNVTTKKTPP 903
Y +RA NSAG G + AT++ PP
Sbjct: 1598 LTELREATWYELRMRACNSAGCGNETAQFATLDYDGSTIPP 1638
Score = 33.1 bits (74), Expect = 1.4
Identities = 61/279 (21%), Positives = 97/279 (34%), Gaps = 46/279 (16%)
Query: 427 VSLDCKPRASPRALSSWKKGD------VSVQEHERISLLNDGGLKIANVTKADAGTYTCM 480
V L C P W K VS+ H I +G L + V D+G YTC
Sbjct: 1367 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIH--TNGTLLLRAVKAEDSGYYTCT 1424
Query: 481 AENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWY---- 536
A N G +L+V P P ++V ++ I TW
Sbjct: 1425 ATNTGGFDTIIVNLLVQVP------PDQPRLTVSKT----------SASSITLTWIPGDN 1468
Query: 537 ----FNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSA--A 590
G + + D S K SS + + LK G + + +SV S +
Sbjct: 1469 GGSSIRGFVLQYSVDNSEEWKDVFISSSERSFKLDSLK-CGTWYKVKLAAKNSVGSGRIS 1527
Query: 591 DLIVRGSPGPPENVKVDE-----ITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQT 645
++I + G + D+ I T A+L+ + + P+ + ++ R + WQ
Sbjct: 1528 EIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAWQG 1587
Query: 646 VTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGG 684
+ + + EL YE R+ A N G G
Sbjct: 1588 LRA------NSSGEVFLTELREATWYELRMRACNSAGCG 1620
Score = 32.3 bits (72), Expect = 2.4
Identities = 17/60 (28%), Positives = 25/60 (41%), Gaps = 5/60 (8%)
Query: 339 CRASGKPKPSYRWLKNGAALVLE-----ERTQIENGALTISNLSVTDSGMFQCIAENKHG 393
C + G P P+ +W K+ + R NG L + + DSG + C A N G
Sbjct: 1371 CNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGG 1430
>gi|237858680 neurofascin isoform 5 precursor [Homo sapiens]
Length = 619
Score = 224 bits (571), Expect = 3e-58
Identities = 172/624 (27%), Positives = 267/624 (42%), Gaps = 49/624 (7%)
Query: 4 PWKQLILLSFIGCLGGEL-----------LLQGPVFIKEPSNSIFPVGSEDKKITLHCEA 52
PW L + LGG + L Q P K+ + V D I + CEA
Sbjct: 8 PWVHAAFLLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHI-VDPRDN-ILIECEA 65
Query: 53 RGNPSPHYRWQLNGSDIDMSMEHRYKLN--GGNLVV---INPNRNWDTGTYQCFATNSLG 107
+GNP+P + W N +++ + R + G LV+ G YQCFA N G
Sbjct: 66 KGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFG 125
Query: 108 TIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVE 167
T +S +LQ + + + V V+EG + L C PPP W+ + +
Sbjct: 126 TALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQ 185
Query: 168 EDSRRFVSQETGHLYISKVEPSDVG-NYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYE 226
+ +R G LY S V D+ +Y+C T+ + P L+ G E
Sbjct: 186 D--KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHT--IQQKNPFTLKVLTTRGVAE 241
Query: 227 PKIEVQFPETLPAA----KGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVL 282
+P+ ++ +G + LEC A G P P I W + G S K K F+ L
Sbjct: 242 RTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKAL 301
Query: 283 EIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRAS 342
I N +ED+G Y C+A N G + A P+W+ K++ +A + CRA+
Sbjct: 302 RITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRAN 361
Query: 343 GKPKPSYRWLKNGAALVL---EERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSA 399
G PKP+ +W+ NG L ++ + + ++ ++QC N+HG + ++A
Sbjct: 362 GNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANA 421
Query: 400 ELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSW-KKGDVSVQEHERISL 458
+ V+ P +P +L++V + + LDC SP W K G S + +
Sbjct: 422 FVSVL-DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHV 480
Query: 459 LNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVI 518
+G L+I + K D G YTC+A N GKA L V +PTRI P + G +V
Sbjct: 481 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 540
Query: 519 LPCQVQHDPLLDIIFTWYFNGALADFKKD-----GSHFEKVGGSSSGDLMIRNIQLKHSG 573
L C+V+HDP L + +W K D G+ +K S L I + + G
Sbjct: 541 LECRVKHDPSLKLTVSW--------LKDDEPLYIGNRMKKEDDS----LTIFGVAERDQG 588
Query: 574 KYVCMVQTGVDSVSSAADLIVRGS 597
Y C+ T +D + A L V G+
Sbjct: 589 SYTCVASTELDQDLAKAYLTVLGN 612
Score = 81.6 bits (200), Expect = 3e-15
Identities = 81/301 (26%), Positives = 128/301 (42%), Gaps = 33/301 (10%)
Query: 322 QLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIE----NGALTISNLS 377
Q KD + D++ EC A G P PS+ W +N + + ++ +G L I S
Sbjct: 46 QSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRS 105
Query: 378 ----VTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKP 433
G +QC A NK G S+ V+ +P + K + +V VQ G+ ++L C P
Sbjct: 106 GGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVV-VQEGAPLTLQCNP 164
Query: 434 RAS-PRALSSWKKGDVS-VQEHERISLLNDGGLKIANVTKADAGT-YTCMAENQFG---- 486
P + W + + + +R+S ++G L +NV D T Y+C A F
Sbjct: 165 PPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQ 224
Query: 487 KANGTTHLVVT-----EPTRITLAP----SNMDVSVGESVILPCQVQHDPLLDIIFTWYF 537
+ N T V+T E T + P S+ V G ++L C P DI WY
Sbjct: 225 QKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDI--AWYK 282
Query: 538 NGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGS 597
G D D + FE + L I N+ + SG+Y C+ + S+ + V+ +
Sbjct: 283 KGG--DLPSDKAKFENFNKA----LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAA 336
Query: 598 P 598
P
Sbjct: 337 P 337
Score = 79.0 bits (193), Expect = 2e-14
Identities = 88/374 (23%), Positives = 155/374 (41%), Gaps = 34/374 (9%)
Query: 46 ITLHCEARGNPSPHYRWQLNGSDIDMSMEHRYKLNGGNLVVINPNRNWDTGTYQCFATNS 105
+ L C A G P+P W G D+ S + +++ L + N + D+G Y C A+N
Sbjct: 264 LLLECIASGVPTPDIAWYKKGGDLP-SDKAKFENFNKALRITNVSEE-DSGEYFCLASNK 321
Query: 106 LGTI---VSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLC----GPPPHSGELSYAWI 158
+G+I +S K +L+ K + + G+ L+C P P + W+
Sbjct: 322 MGSIRHTISVRVKAAPYWLDEPKNLI-----LAPGEDGRLVCRANGNPKP-----TVQWM 371
Query: 159 FNEYP-SFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLR 217
N P + R V+ +T + + S Y C ++ + +L + VL
Sbjct: 372 VNGEPLQSAPPNPNREVAGDT--IIFRDTQISSRAVYQCNTSN--EHGYLLANAFVSVL- 426
Query: 218 SDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINW-RRSDGLPFSSKIKLR 276
+ P++ + + + +L+C G+PIP + W + G
Sbjct: 427 ------DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHV 480
Query: 277 KFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLY 336
+G LEI ++ED G Y C+A N GK + RL ++ +D ++
Sbjct: 481 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 540
Query: 337 WECRASGKP--KPSYRWLKNGAALVLEERTQIENGALTISNLSVTDSGMFQCIAENKHGL 394
ECR P K + WLK+ L + R + E+ +LTI ++ D G + C+A +
Sbjct: 541 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQ 600
Query: 395 VYSSAELKVVASAP 408
+ A L V+ + P
Sbjct: 601 DLAKAYLTVLGNCP 614
>gi|157311649 neogenin homolog 1 [Homo sapiens]
Length = 1461
Score = 220 bits (561), Expect = 5e-57
Identities = 273/1064 (25%), Positives = 444/1064 (41%), Gaps = 153/1064 (14%)
Query: 28 FIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDIDM-SMEHRYKLNGGNLVV 86
F+ EP +++ GS + L+C A PSP W+ +G+ +++ S + R L G+L +
Sbjct: 55 FLVEPVDTLSVRGSS---VILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFI 111
Query: 87 IN----PNRNWDTGTYQCFAT-NSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVV 141
N + D G YQC AT SLGTI+SR AKL A L F T SV G +
Sbjct: 112 SNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRF-TSQPEPSSVYAGNNAI 170
Query: 142 LLCGPPPHSGELSYA-WIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVVTS 200
L C ++ + + W N P +++ R + +G L IS D G Y CVV S
Sbjct: 171 LNC--EVNADLVPFVRWEQNRQPLLLDD---RVIKLPSGMLVISNATEGDGGLYRCVVES 225
Query: 201 MVTNARVLGSPTPLVLRSDGVMGEYEPKIEV-------QFPETLPAAKGSTVKLECFALG 253
G P SD V + P EV + P L G V L C A G
Sbjct: 226 --------GGPPKY---SDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASG 274
Query: 254 NPIPQINWRRSD-GLPFSSKIKLRKFSG-VLEIPNFQQEDAGSYECIAENSRGKNVARGR 311
P P I W +++ L S +L +G LEI + ++DAG+Y CIA+N A+
Sbjct: 275 LPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAE 334
Query: 312 LTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQI-ENGA 370
LT A+P +++ ++ + +EC +GKP P+ +W+KNG ++ + +I +
Sbjct: 335 LTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHN 394
Query: 371 LTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLD 430
L + L +D G +QCIAEN G + A+L ++ AP + P+ + V SLVS
Sbjct: 395 LQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPA-TTGPLPSAPRDVVASLVSTR 453
Query: 431 C------KPRASPRALSS-----WKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTC 479
P + P + + K ++ + E S + + I N+ A +
Sbjct: 454 FIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRV 513
Query: 480 MAENQFGKANGTTHLVVTEPTRITL---APSNMDVSVGESVILPCQVQHDPLLDIIFTWY 536
MA+N+ G + L V + L AP+ + + I TW
Sbjct: 514 MAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPT-------------SITVTWE 560
Query: 537 F----NGALADFK----KDGSHFEKVGGSSSGDLMIRNIQ--LKHSGKYVCMVQ--TGVD 584
NG + ++K + G+ E+ SS I ++ ++S + V + GV
Sbjct: 561 TPVSGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVS 620
Query: 585 SVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKD--NHSPVISYSIQARTPFSVG 642
+ A + P+N+ ++ + + W+ + + Y I+ R
Sbjct: 621 TPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKA---- 676
Query: 643 WQTVTTVPEVIDGKTHTATVVE-LNPWVEYEFRVVASNKIGGGEPS--LPSEKVRT---E 696
+ V E + T + ++E L+ EY FRV A G G + L +E + E
Sbjct: 677 -SRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDE 735
Query: 697 EAVPEVPPS-EVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTS 755
VPEVP S V + +V++W P E QN GY + + G+ + +
Sbjct: 736 TRVPEVPSSLHVRP---LVTSIVVSW--TPPENQNIVVRGYAIGY---GIGSPHAQTIKV 787
Query: 756 PDTPRYVFRNESIVPYSPYEVKVGVYNNKGEG-------------------------PFS 790
RY + E++ P S Y + + +NN GEG P++
Sbjct: 788 DYKQRY-YTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYT 846
Query: 791 PVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSW--NTIPWKLSNGHLLGYEVRYWNGGGK 848
PV + P + P V A+ LS I ++W N++P H + RY+ K
Sbjct: 847 PVP-----DPTPMMPPVGVQASILSHDTIRITWADNSLP-----KHQKITDSRYYTVRWK 896
Query: 849 EE--SSSKMKVAGNETSARL-RGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQ 905
+++K K A T + L GLK N Y +V + +S T + TT + P+
Sbjct: 897 TNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTS 956
Query: 906 PPGNVVWNATDTK---VLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQ------VLNTN 956
PP +V + + K +++NW+ E ++TGY ++Y T + V+
Sbjct: 957 PPKDVTVVSKEGKPKTIIVNWQ--PPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNR 1014
Query: 957 KTSAELVLPIKEDYIIEVKATTDGGDGTSSE--QIRIPRITSMD 998
T L + Y +++A G G SE Q R P+ S D
Sbjct: 1015 LTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKADSSD 1058
Score = 115 bits (289), Expect = 2e-25
Identities = 215/968 (22%), Positives = 354/968 (36%), Gaps = 128/968 (13%)
Query: 20 ELLLQG-PVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDIDMSMEHRYK 78
+L++ G P F +P S G+ L+CE + P RW+ N + + + K
Sbjct: 145 KLIVAGLPRFTSQPEPSSVYAGNN---AILNCEVNADLVPFVRWEQNRQPLLLD-DRVIK 200
Query: 79 LNGGNLVVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFA----YLENFKTKMRSTVSV 134
L G LV+ N D G Y+C + S E +L+ + + + + V
Sbjct: 201 LPSGMLVISNATEG-DGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLV 259
Query: 135 RE-GQGVVLLCG----PPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPS 189
R GQ VVL C P P + W+ NE + E S R V G L IS V
Sbjct: 260 RVIGQDVVLPCVASGLPTP-----TIKWMKNE-EALDTESSERLVLLAGGSLEISDVTED 313
Query: 190 DVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLEC 249
D G Y C+ + + + L +++ +P+ Q P + A + + EC
Sbjct: 314 DAGTYFCIADN---GNETIEAQAELTVQA-------QPEFLKQ-PTNIYAHESMDIVFEC 362
Query: 250 FALGNPIPQINW-RRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVA 308
G P P + W + D + S K+ K L++ + D G Y+CIAEN G A
Sbjct: 363 EVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHN-LQVLGLVKSDEGFYQCIAENDVGNAQA 421
Query: 309 RGRLTYYAKPHWV-----QLIKDVEIAVEDS----LYWECRASGKPKP----SYRWLKNG 355
+L +DV ++ + L W AS S + K G
Sbjct: 422 GAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEG 481
Query: 356 AALVLEERTQIENGA------LTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPD 409
A R ++EN + +TI NL +F+ +A+NKHG SSA L+V
Sbjct: 482 IA-----RERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEV 536
Query: 410 FSKNPMKKLVQVQVGSLVSLDCK---PRASPRALSSWK-----KG-----DVSVQEHERI 456
P L + S S+ P + + ++K KG DV V H
Sbjct: 537 QLPGPAPNL-RAYAASPTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDVDVSSHS-- 593
Query: 457 SLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRI-TLAPSNMDVSVGE 515
I + K ++ +A N+ G T + V + + + AP N+ + V
Sbjct: 594 -------YTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRN 646
Query: 516 SVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQ-----LK 570
S + + P G ++K + SG + + I+ +
Sbjct: 647 SKSI--MIHWQPPAPATQNGQITGYKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTE 704
Query: 571 HSGKYVCMVQTGVDSVSS-------AADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKD 623
++ + + G + +DL P P ++ V + T+ +SW ++
Sbjct: 705 YNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLV-TSIVVSWTPPEN 763
Query: 624 NHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGG 683
+ V Y+I + +G T+ +D K T+ L+P Y + A N +G
Sbjct: 764 QNIVVRGYAIG----YGIGSPHAQTIK--VDYKQRYYTIENLDPSSHYVITLKAFNNVGE 817
Query: 684 GEPSLPSEKVRTE-------------------EAVPEVPPSEVNGGGGSRSELVITW--D 722
G P S R + P +PP V S + ITW +
Sbjct: 818 GIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADN 877
Query: 723 PVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYN 782
+P+ + + Y V ++ T + + + + P + YE V V
Sbjct: 878 SLPKHQKITDSRYYTVRWK---TNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTK 934
Query: 783 NKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRY 842
+ +S + E PT P V+ S + N P +NG + GY + Y
Sbjct: 935 GRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKPKTIIVNWQPPSEANGKITGYIIYY 994
Query: 843 WNGGGKEESSSKMK-VAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKT 901
E ++ V GN + +++ L + YY ++A NS G GP S V T K
Sbjct: 995 STDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKA 1054
Query: 902 PPSQPPGN 909
S N
Sbjct: 1055 DSSDKMPN 1062
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 211 bits (538), Expect = 2e-54
Identities = 203/753 (26%), Positives = 317/753 (42%), Gaps = 87/753 (11%)
Query: 190 DVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLEC 249
D G+Y CV + + A + + L D Q P + A G LEC
Sbjct: 120 DEGSYVCVARNYLGEAVSRNASLEVALLRDDFR---------QNPTDVVVAAGEPAILEC 170
Query: 250 FA-LGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVA 308
G+P P I W++ + ++ G L I N ++ DAG Y C+ N G+ +
Sbjct: 171 QPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDS 230
Query: 309 R-GRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIE 367
LT + +P +++ + + E+++ + C+ G P+P+ RW K+ A L +
Sbjct: 231 DPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKD 290
Query: 368 NGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLV 427
+ L I TD G + CIAEN+ G + +SA L V + P F P ++ V G V
Sbjct: 291 DYTLRIKKTMSTDEGTYMCIAENRVGKMEASATL-TVRAPPQFVVRPRDQI--VAQGRTV 347
Query: 428 SLDCKPRASPRALSSW-KKGDVSV-------QEHERISLLNDGGLKIANVTKADAGTYTC 479
+ C+ + +P+ W K+G ++ Q + R S+ G L I N+ ++DAG Y C
Sbjct: 348 TFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYIC 407
Query: 480 MAENQFGKANGTTHLVVTE------PTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIF 533
A G L VT+ P I P+N ++V + +L C+ DPL +
Sbjct: 408 QALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPL--PVI 465
Query: 534 TWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMV--QTGVDSVSSAAD 591
+W G + + ++ G L I+N+++ +G Y C+ +G S S+ D
Sbjct: 466 SWLKEGFTFPGRDPRATIQE-----QGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLD 520
Query: 592 LIVRGS-----------PGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQA-RTPF 639
+ G+ PGPP +V ++T + LSW+ G P +Y I+A
Sbjct: 521 VTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSV 580
Query: 640 SVGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAV 699
S WQTV KT TV L P Y F V A N G +PS S+ VRT++
Sbjct: 581 SNSWQTVAN-----HVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDIS 635
Query: 700 PE---VPPSEVNGGGG------------SRSELVITW--DPVPEELQNGEGFGYVVAFRP 742
P V +V G + + + +TW D P+ +Q GY V +R
Sbjct: 636 PPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQ-----GYRVMYRQ 690
Query: 743 L----GVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSA 798
++W P V N + YE+KV Y N+ +G S TV +
Sbjct: 691 TSGLQATSSWQNLDAKVPTERSAVLVN--LKKGVTYEIKVRPYFNEFQGMDSESKTVRTT 748
Query: 799 EEEPTVAPSQV---SANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKM 855
EE P+ P V + S +S+ I VSW+ P NG + Y++ W G +
Sbjct: 749 EEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKI--WCLGNETRFHINK 806
Query: 856 KVAGNETSARLRGLKSNLAYYTAVRAYNSAGAG 888
V S + GL + Y V A SAG G
Sbjct: 807 TVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVG 839
Score = 194 bits (492), Expect = 5e-49
Identities = 204/768 (26%), Positives = 320/768 (41%), Gaps = 90/768 (11%)
Query: 26 PVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNG----SDIDMSMEHRYKLNG 81
P ++ PS+ I S+ + TL+C+A G P+P W +G +D D HR L
Sbjct: 47 PRIVEHPSDVIV---SKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPS 103
Query: 82 GNL----VVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREG 137
G+L +V D G+Y C A N LG VSR A L+ A L + + + V V G
Sbjct: 104 GSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAG 163
Query: 138 QGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCV 197
+ +L C PP E + W + +D +S G L IS SD G YTCV
Sbjct: 164 EPAILECQPPRGHPEPTIYW---KKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCV 220
Query: 198 VTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIP 257
T+MV P L + +E ++ P + V+ C G+P P
Sbjct: 221 GTNMVGERD--SDPAELTV--------FERPTFLRRPINQVVLEEEAVEFRCQVQGDPQP 270
Query: 258 QINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAK 317
+ W++ D + + K L I D G+Y CIAEN GK A LT A
Sbjct: 271 TVRWKKDDADLPRGRYDI-KDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAP 329
Query: 318 PHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAA-LVLEERTQIEN-------- 368
P +V +D +A ++ + C G P+P+ W K G+ L+ + Q N
Sbjct: 330 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 389
Query: 369 GALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVV-----ASAPDFSKNPMKKLVQVQV 423
G LTI+N+ +D+G + C A G + + A+L+V P + P + + V
Sbjct: 390 GDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDG 449
Query: 424 GSLVSLDCKPRASPRALSSW-KKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAE 482
+L L CK P + SW K+G R ++ G L+I N+ +D GTYTC+A
Sbjct: 450 TAL--LKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVAT 507
Query: 483 NQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALA 542
+ G+ + + L VTE + T++ N D+S QV + +W G
Sbjct: 508 SSSGETSWSAVLDVTE-SGATIS-KNYDLSDLPGPPSKPQVTDVTKNSVTLSWQ-PGTPG 564
Query: 543 DFKKDGSHFEKVGG--SSSGDLMIRNIQ--------LKHSGKYVCMVQT----GVDSVSS 588
E S+S + +++ L+ + Y+ MV+ G+ S
Sbjct: 565 TLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSP 624
Query: 589 AADLIVRGSPGPP----ENVKVDE--------------ITDTTAQLSWKEGKDNHSPVIS 630
+D + PP ++ +V + +T TT Q++W + +
Sbjct: 625 MSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQF-IQG 683
Query: 631 YSIQARTPFSVGWQTVTTVPEVIDGKTHT---ATVVELNPWVEYEFRV-VASNKIGGGEP 686
Y + R + T+ + +D K T A +V L V YE +V N+ G +
Sbjct: 684 YRVMYRQTSGL---QATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDS 740
Query: 687 SLPSEKVRTEEAVPEVPPSEV---NGGGGSRSELVITWDPVPEELQNG 731
S+ VRT E P PP V G + + + ++WDP P + QNG
Sbjct: 741 E--SKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNG 786
Score = 179 bits (455), Expect = 9e-45
Identities = 215/830 (25%), Positives = 324/830 (39%), Gaps = 96/830 (11%)
Query: 224 EYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSDG----------------L 267
++ P+I V+ P + +KG L C A G P P I W + DG L
Sbjct: 44 DFPPRI-VEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYK-DGERVETDKDDPRSHRMLL 101
Query: 268 PFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYA--KPHWVQLIK 325
P S LR G P D GSY C+A N G+ V+R A + + Q
Sbjct: 102 PSGSLFFLRIVHGRRSKP-----DEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPT 156
Query: 326 DVEIAVEDSLYWECRAS-GKPKPSYRWLKNGAALV-LEERTQIENGALTISNLSVTDSGM 383
DV +A + EC+ G P+P+ W K+ + EER I G L ISN +D+GM
Sbjct: 157 DVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGM 216
Query: 384 FQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSW 443
+ C+ N G S V P F + P+ ++V + V C+ + P+ W
Sbjct: 217 YTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEE--EAVEFRCQVQGDPQPTVRW 274
Query: 444 KKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRIT 503
KK D + R + +D L+I D GTY C+AEN+ GK + L V P +
Sbjct: 275 KKDDADLPRG-RYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFV 333
Query: 504 LAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLM 563
+ P + V+ G +V PC+ + +P + + + L + + S +GDL
Sbjct: 334 VRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLT 393
Query: 564 IRNIQLKHSGKYVCMVQTGVDSVSSAADL----IVRGSPGP-----PENVKVDEITDTTA 614
I NIQ +G Y+C T S+ + A L ++ P P P N + D TA
Sbjct: 394 ITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTL--AVDGTA 451
Query: 615 QLSWKEGKDNHSPVIS-----YSIQARTP-FSVGWQTVTTVPEVIDGKTHTATVVELNPW 668
L K D PVIS ++ R P ++ Q + + T T T V +
Sbjct: 452 LLKCKATGDP-LPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSS 510
Query: 669 VEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDP-VPEE 727
E + V G S K +P PPS+ +++ + ++W P P
Sbjct: 511 GETSWSAVLDVTESGATIS----KNYDLSDLPG-PPSKPQVTDVTKNSVTLSWQPGTPGT 565
Query: 728 LQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKG-- 785
L Y++ V+ QTV T Y R + P + Y V N +G
Sbjct: 566 LPAS---AYIIEAFSQSVSNSWQTVANHVKTTLYTVRG--LRPNTIYLFMVRAINPQGLS 620
Query: 786 -EGPFS-PVTTVFSAEEEPTVAPSQVSANS------------LSSSEIEVSWNTIPWKLS 831
P S PV T + V QV L+ + ++V+W
Sbjct: 621 DPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTV---DRQ 677
Query: 832 NGHLLGYEVRYWNGGGKEESSSKMKVAGN---ETSARLRGLKSNLAYYTAVRAYNSAGAG 888
+ GY V Y G + +SS + E SA L LK + Y VR Y + G
Sbjct: 678 PQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQG 737
Query: 889 PFSATVNVTTKKTPPSQPPGNV----VWNATDTKVLLNWEQVKAMENESEVTGYKVFYRT 944
S + V T + PS PP +V V + T + ++W+ + YK++
Sbjct: 738 MDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIW--- 794
Query: 945 SSQNNVQVLNTNKTSAELVLPI-------KEDYIIEVKATTDGGDGTSSE 987
N + NKT + + Y +EV A+T G G SE
Sbjct: 795 -CLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSE 843
>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2b [Homo sapiens]
Length = 1378
Score = 211 bits (538), Expect = 2e-54
Identities = 203/753 (26%), Positives = 317/753 (42%), Gaps = 87/753 (11%)
Query: 190 DVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLEC 249
D G+Y CV + + A + + L D Q P + A G LEC
Sbjct: 104 DEGSYVCVARNYLGEAVSRNASLEVALLRDDFR---------QNPTDVVVAAGEPAILEC 154
Query: 250 FA-LGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVA 308
G+P P I W++ + ++ G L I N ++ DAG Y C+ N G+ +
Sbjct: 155 QPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDS 214
Query: 309 R-GRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIE 367
LT + +P +++ + + E+++ + C+ G P+P+ RW K+ A L +
Sbjct: 215 DPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKD 274
Query: 368 NGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLV 427
+ L I TD G + CIAEN+ G + +SA L V + P F P ++ V G V
Sbjct: 275 DYTLRIKKTMSTDEGTYMCIAENRVGKMEASATL-TVRAPPQFVVRPRDQI--VAQGRTV 331
Query: 428 SLDCKPRASPRALSSW-KKGDVSV-------QEHERISLLNDGGLKIANVTKADAGTYTC 479
+ C+ + +P+ W K+G ++ Q + R S+ G L I N+ ++DAG Y C
Sbjct: 332 TFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYIC 391
Query: 480 MAENQFGKANGTTHLVVTE------PTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIF 533
A G L VT+ P I P+N ++V + +L C+ DPL +
Sbjct: 392 QALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPL--PVI 449
Query: 534 TWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMV--QTGVDSVSSAAD 591
+W G + + ++ G L I+N+++ +G Y C+ +G S S+ D
Sbjct: 450 SWLKEGFTFPGRDPRATIQE-----QGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLD 504
Query: 592 LIVRGS-----------PGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQA-RTPF 639
+ G+ PGPP +V ++T + LSW+ G P +Y I+A
Sbjct: 505 VTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSV 564
Query: 640 SVGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAV 699
S WQTV KT TV L P Y F V A N G +PS S+ VRT++
Sbjct: 565 SNSWQTVAN-----HVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDIS 619
Query: 700 PE---VPPSEVNGGGG------------SRSELVITW--DPVPEELQNGEGFGYVVAFRP 742
P V +V G + + + +TW D P+ +Q GY V +R
Sbjct: 620 PPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQ-----GYRVMYRQ 674
Query: 743 L----GVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSA 798
++W P V N + YE+KV Y N+ +G S TV +
Sbjct: 675 TSGLQATSSWQNLDAKVPTERSAVLVN--LKKGVTYEIKVRPYFNEFQGMDSESKTVRTT 732
Query: 799 EEEPTVAPSQV---SANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKM 855
EE P+ P V + S +S+ I VSW+ P NG + Y++ W G +
Sbjct: 733 EEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKI--WCLGNETRFHINK 790
Query: 856 KVAGNETSARLRGLKSNLAYYTAVRAYNSAGAG 888
V S + GL + Y V A SAG G
Sbjct: 791 TVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVG 823
Score = 194 bits (493), Expect = 4e-49
Identities = 211/791 (26%), Positives = 330/791 (41%), Gaps = 94/791 (11%)
Query: 7 QLILLSFIGC-LGGELLLQG---PVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRW 62
QL+L F+ + G L Q P ++ PS+ I S+ + TL+C+A G P+P W
Sbjct: 8 QLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIV---SKGEPTTLNCKAEGRPTPTIEW 64
Query: 63 QLNG----SDIDMSMEHRYKLNGGNL----VVINPNRNWDTGTYQCFATNSLGTIVSREA 114
+G +D D HR L G+L +V D G+Y C A N LG VSR A
Sbjct: 65 YKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNA 124
Query: 115 KLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFV 174
L+ A L + + + V V G+ +L C PP E + W + +D +
Sbjct: 125 SLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYW---KKDKVRIDDKEERI 181
Query: 175 SQETGHLYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFP 234
S G L IS SD G YTCV T+MV P L + +E ++ P
Sbjct: 182 SIRGGKLMISNTRKSDAGMYTCVGTNMVGERD--SDPAELTV--------FERPTFLRRP 231
Query: 235 ETLPAAKGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGS 294
+ V+ C G+P P + W++ D + + K L I D G+
Sbjct: 232 INQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDI-KDDYTLRIKKTMSTDEGT 290
Query: 295 YECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKN 354
Y CIAEN GK A LT A P +V +D +A ++ + C G P+P+ W K
Sbjct: 291 YMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKE 350
Query: 355 GAA-LVLEERTQIEN--------GALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVV- 404
G+ L+ + Q N G LTI+N+ +D+G + C A G + + A+L+V
Sbjct: 351 GSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTD 410
Query: 405 ----ASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSW-KKGDVSVQEHERISLL 459
P + P + + V +L L CK P + SW K+G R ++
Sbjct: 411 VLTDRPPPIILQGPANQTLAVDGTAL--LKCKATGDPLPVISWLKEGFTFPGRDPRATIQ 468
Query: 460 NDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVIL 519
G L+I N+ +D GTYTC+A + G+ + + L VTE + T++ N D+S
Sbjct: 469 EQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTE-SGATIS-KNYDLSDLPGPPS 526
Query: 520 PCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGG--SSSGDLMIRNIQ--------L 569
QV + +W G E S+S + +++ L
Sbjct: 527 KPQVTDVTKNSVTLSWQ-PGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGL 585
Query: 570 KHSGKYVCMVQT----GVDSVSSAADLIVRGSPGPP----ENVKVDE------------- 608
+ + Y+ MV+ G+ S +D + PP ++ +V +
Sbjct: 586 RPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPV 645
Query: 609 -ITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHT---ATVVE 664
+T TT Q++W + + Y + R + T+ + +D K T A +V
Sbjct: 646 VLTPTTVQVTWTVDRQPQF-IQGYRVMYRQTSGL---QATSSWQNLDAKVPTERSAVLVN 701
Query: 665 LNPWVEYEFRV-VASNKIGGGEPSLPSEKVRTEEAVPEVPPSEV---NGGGGSRSELVIT 720
L V YE +V N+ G + S+ VRT E P PP V G + + + ++
Sbjct: 702 LKKGVTYEIKVRPYFNEFQGMDSE--SKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVS 759
Query: 721 WDPVPEELQNG 731
WDP P + QNG
Sbjct: 760 WDPPPPDHQNG 770
Score = 180 bits (456), Expect = 7e-45
Identities = 219/843 (25%), Positives = 329/843 (39%), Gaps = 99/843 (11%)
Query: 214 LVLRSDGV---MGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSDG---- 266
L +R DG ++ P+I V+ P + +KG L C A G P P I W + DG
Sbjct: 15 LYVRVDGSRLRQEDFPPRI-VEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYK-DGERVE 72
Query: 267 ------------LPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTY 314
LP S LR G P D GSY C+A N G+ V+R
Sbjct: 73 TDKDDPRSHRMLLPSGSLFFLRIVHGRRSKP-----DEGSYVCVARNYLGEAVSRNASLE 127
Query: 315 YA--KPHWVQLIKDVEIAVEDSLYWECRAS-GKPKPSYRWLKNGAALV-LEERTQIENGA 370
A + + Q DV +A + EC+ G P+P+ W K+ + EER I G
Sbjct: 128 VALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGK 187
Query: 371 LTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLD 430
L ISN +D+GM+ C+ N G S V P F + P+ ++V + V
Sbjct: 188 LMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEE--EAVEFR 245
Query: 431 CKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANG 490
C+ + P+ WKK D + R + +D L+I D GTY C+AEN+ GK
Sbjct: 246 CQVQGDPQPTVRWKKDDADLPRG-RYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEA 304
Query: 491 TTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSH 550
+ L V P + + P + V+ G +V PC+ + +P + + + L +
Sbjct: 305 SATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQP 364
Query: 551 FEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADL----IVRGSPGP-----P 601
+ S +GDL I NIQ +G Y+C T S+ + A L ++ P P P
Sbjct: 365 NSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGP 424
Query: 602 ENVKVDEITDTTAQLSWKEGKDNHSPVIS-----YSIQARTP-FSVGWQTVTTVPEVIDG 655
N + D TA L K D PVIS ++ R P ++ Q + +
Sbjct: 425 ANQTL--AVDGTALLKCKATGDP-LPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRIS 481
Query: 656 KTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRS 715
T T T V + E + V G S K +P PPS+ +++
Sbjct: 482 DTGTYTCVATSSSGETSWSAVLDVTESGATIS----KNYDLSDLPG-PPSKPQVTDVTKN 536
Query: 716 ELVITWDP-VPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPY 774
+ ++W P P L Y++ V+ QTV T Y R + P + Y
Sbjct: 537 SVTLSWQPGTPGTLPAS---AYIIEAFSQSVSNSWQTVANHVKTTLYTVRG--LRPNTIY 591
Query: 775 EVKVGVYNNKG---EGPFS-PVTTVFSAEEEPTVAPSQVSANS------------LSSSE 818
V N +G P S PV T + V QV L+ +
Sbjct: 592 LFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTT 651
Query: 819 IEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGN---ETSARLRGLKSNLAY 875
++V+W + GY V Y G + +SS + E SA L LK + Y
Sbjct: 652 VQVTWTV---DRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTY 708
Query: 876 YTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNV----VWNATDTKVLLNWEQVKAMEN 931
VR Y + G S + V T + PS PP +V V + T + ++W+
Sbjct: 709 EIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQ 768
Query: 932 ESEVTGYKVFYRTSSQNNVQVLNTNKTSAELVLPI-------KEDYIIEVKATTDGGDGT 984
+ YK++ N + NKT + + Y +EV A+T G G
Sbjct: 769 NGIIQEYKIW----CLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGV 824
Query: 985 SSE 987
SE
Sbjct: 825 KSE 827
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 203 bits (516), Expect = 8e-52
Identities = 220/857 (25%), Positives = 349/857 (40%), Gaps = 89/857 (10%)
Query: 16 CLGGELLLQG--PVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNG----SDI 69
C G L + P ++ PS+ I S+ + TL+C+A G P+P W G +D
Sbjct: 17 CSGSRLRQEDFPPRIVEHPSDLIV---SKGEPATLNCKAEGRPTPTIEWYKGGERVETDK 73
Query: 70 DMSMEHRYKLNGGNL----VVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAYLENFK 125
D HR L G+L +V D G Y C A N LG VS A L+ A L +
Sbjct: 74 DDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDF 133
Query: 126 TKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISK 185
+ S V V G+ V+ C PP E + +W + P +D ++ G L I+
Sbjct: 134 RQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPL---DDKDERITIRGGKLMITY 190
Query: 186 VEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTV 245
SD G Y CV T+MV + ++ R V+ P L +
Sbjct: 191 TRKSDAGKYVCVGTNMVGERESEVAELTVLERPS----------FVKRPSNLAVTVDDSA 240
Query: 246 KLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGK 305
+ +C A G+P+P + WR+ DG S+ ++R L+I D GSY C+AEN GK
Sbjct: 241 EFKCEARGDPVPTVRWRKDDGELPKSRYEIRD-DHTLKIRKVTAGDMGSYTCVAENMVGK 299
Query: 306 NVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVL----- 360
A LT PH+V +D +A+ ++ ++C A+G P+P+ W + G+ +L
Sbjct: 300 AEASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQP 359
Query: 361 ---EERTQI-ENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVV-----ASAPDFS 411
R + + G LTI+N+ +D G + C N G + + A L+V P
Sbjct: 360 PQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIR 419
Query: 412 KNPMKKLVQVQVGSLVSLDCKPRASPRALSSWKKGDVSVQ-EHERISLLNDGGLKIANVT 470
+ P+ + V V G+ V L C SP W+K V V + RI L +G L+I
Sbjct: 420 QGPVNQTVAVD-GTFV-LSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAK 477
Query: 471 KADAGTYTCMAENQFGKANGTTHLVV------------TEPTRITLAPSNMDVSVGESVI 518
D G YTC+A G+A + ++ V T+P I APS +V+
Sbjct: 478 LGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNT 537
Query: 519 LPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCM 578
+ Q + T Y A + GS ++ V + + LK + Y+ +
Sbjct: 538 VTLSWQPNLNSGATPTSYIIEAFS--HASGSSWQTVAENVKTETSAIK-GLKPNAIYLFL 594
Query: 579 VQT----GVDSVSSAADL-----IVRGSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVI 629
V+ G+ S +D ++ S G E+ + L + S +
Sbjct: 595 VRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEV 654
Query: 630 SYSIQARTPFSVGWQTV------------TTVPEVIDGKTHTATVVELNPWVEYEFRV-V 676
+++ ++ + G++ + V EV ++ + +L V YE +
Sbjct: 655 HWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARP 714
Query: 677 ASNKIGGGEPSLPSEKVRTEEAVPEVPPS--EVNGGGGSRSELVITWDPVPEELQNGEGF 734
N+ G + + K T E P PP V+ G+ + ++++W P PE+ QNG
Sbjct: 715 FFNEFQGADSEIKFAK--TLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQ 772
Query: 735 GYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFS-PVT 793
Y V LG T + + D + +VP Y V+V G G S P
Sbjct: 773 EYKVWC--LGNETRYH-INKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEPQF 829
Query: 794 TVFSAEEEPTVAPSQVS 810
A P QVS
Sbjct: 830 IQLDAHGNPVSPEDQVS 846
Score = 201 bits (511), Expect = 3e-51
Identities = 199/761 (26%), Positives = 317/761 (41%), Gaps = 102/761 (13%)
Query: 190 DVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLEC 249
D G Y CV + + A + + + D Q P + A G +EC
Sbjct: 102 DEGVYVCVARNYLGEAVSHNASLEVAILRDDFR---------QNPSDVMVAVGEPAVMEC 152
Query: 250 FA-LGNPIPQINWRRSDGLPFSSK---IKLRKFSGVLEIPNFQQEDAGSYECIAENSRGK 305
G+P P I+W++ DG P K I +R G L I ++ DAG Y C+ N G+
Sbjct: 153 QPPRGHPEPTISWKK-DGSPLDDKDERITIR--GGKLMITYTRKSDAGKYVCVGTNMVGE 209
Query: 306 NVAR-GRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERT 364
+ LT +P +V+ ++ + V+DS ++C A G P P+ RW K+ L
Sbjct: 210 RESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYE 269
Query: 365 QIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVG 424
++ L I ++ D G + C+AEN G +SA L V P F P ++V + G
Sbjct: 270 IRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATL-TVQEPPHFVVKPRDQVVAL--G 326
Query: 425 SLVSLDCKPRASPRALSSWKK-GDVSV-------QEHERISLLNDGGLKIANVTKADAGT 476
V+ C+ +P+ W++ G ++ Q R S+ G L I NV ++D G
Sbjct: 327 RTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGY 386
Query: 477 YTCMAENQFGKANGTTHLVVTE------PTRITLAPSNMDVSVGESVILPCQVQHDPLLD 530
Y C N G +L VT+ P I P N V+V + +L C P+
Sbjct: 387 YICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPT 446
Query: 531 IIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAA 590
I+ W +G L + ++ +G L IR +L +G+Y C+ T + +A
Sbjct: 447 IL--WRKDGVLVSTQDS-----RIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSA 499
Query: 591 DLIVRGS---------------PGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQA 635
+ V+ P P +V +++ T LSW+ ++ + SY I+A
Sbjct: 500 YIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEA 559
Query: 636 RTPFS-VGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVR 694
+ S WQTV + KT T+ + L P Y F V A+N G +PS S+ V+
Sbjct: 560 FSHASGSSWQTVAE-----NVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVK 614
Query: 695 TEEAVPE---VPPSEVNGGGG------------SRSELVITW--DPVPEELQNGEGFGYV 737
T++ +P V +V G S S + + W D + +Q GY
Sbjct: 615 TQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQ-----GYK 669
Query: 738 VAFRPLGV----TTWIQTVVTSPDTPRYVFRNESIVP----YSPYEVKVGVYNNKGEGPF 789
+ +RP G + W+ V +P +N ++P YE+K + N+ +G
Sbjct: 670 ILYRPSGANHGESDWLVFEVRTP------AKNSVVIPDLRKGVNYEIKARPFFNEFQGAD 723
Query: 790 SPVTTVFSAEEEPTVAPS--QVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGG 847
S + + EE P+ P VS N + + I VSW P NG + Y+V W G
Sbjct: 724 SEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKV--WCLGN 781
Query: 848 KEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAG 888
+ V G+ S + L + Y V A AG+G
Sbjct: 782 ETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSG 822
Score = 169 bits (427), Expect = 2e-41
Identities = 212/850 (24%), Positives = 326/850 (38%), Gaps = 109/850 (12%)
Query: 224 EYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSDG---------------LP 268
++ P+I V+ P L +KG L C A G P P I W + LP
Sbjct: 26 DFPPRI-VEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLP 84
Query: 269 FSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYA--KPHWVQLIKD 326
S LR G P D G Y C+A N G+ V+ A + + Q D
Sbjct: 85 SGSLFFLRIVHGRKSRP-----DEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSD 139
Query: 327 VEIAVEDSLYWECRAS-GKPKPSYRWLKNGAALV-LEERTQIENGALTISNLSVTDSGMF 384
V +AV + EC+ G P+P+ W K+G+ L +ER I G L I+ +D+G +
Sbjct: 140 VMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKY 199
Query: 385 QCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWK 444
C+ N G S V P F K P + V V C+ R P W+
Sbjct: 200 VCVGTNMVGERESEVAELTVLERPSFVKRPSN--LAVTVDDSAEFKCEARGDPVPTVRWR 257
Query: 445 KGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITL 504
K D + + R + +D LKI VT D G+YTC+AEN GKA + L V EP +
Sbjct: 258 KDDGELPK-SRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVV 316
Query: 505 APSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMI 564
P + V++G +V C+ +P I + + L + + S +GDL I
Sbjct: 317 KPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTI 376
Query: 565 RNIQLKHSGKYVCMVQTGVDSVSSAADLIVRG--SPGPPENVKVDEITDTTAQLSWKEGK 622
N+Q G Y+C S+ + A L V + PP ++ + T A
Sbjct: 377 TNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAV------- 429
Query: 623 DNHSPVISYSIQARTPFSVGWQTVTTVPEVID------------------GKTHTATVVE 664
+ + V+S ++ W+ + D G T T +
Sbjct: 430 -DGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIA 488
Query: 665 LNPWVEYEFRVVASNKIGGGEPSLPSEKVR-TEEAVPEVPPSEVNGGGGSRSELVITWDP 723
P E + S I E +P + R T+ + PS+ SR+ + ++W P
Sbjct: 489 STPSGEATW----SAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQP 544
Query: 724 VPEELQNGEG-FGYVV-AFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVY 781
L +G Y++ AF ++W QTV + T + + P + Y V
Sbjct: 545 ---NLNSGATPTSYIIEAFSHASGSSW-QTVAENVKTETSAIKG--LKPNAIYLFLVRAA 598
Query: 782 NNKGEGPFSPVTTVFSAEEE-PT---VAPSQV------------SANSLSSSEIEVSWNT 825
N G S ++ ++ PT V QV + LSSS IEV W
Sbjct: 599 NAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTV 658
Query: 826 IPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGN---ETSARLRGLKSNLAYYTAVRAY 882
+ ++ GY++ Y G S + + S + L+ + Y R +
Sbjct: 659 ---DQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPF 715
Query: 883 NSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATD---TKVLLNWEQVKAMENESEVTGYK 939
+ G S T + PS PP V + D T +L++W+ V YK
Sbjct: 716 FNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYK 775
Query: 940 VFYRTSSQNNVQVLNTNKT----SAELVLPIKED---YIIEVKATTDGGDGTSSEQIRIP 992
V+ N + NKT + +V+P Y +EV A+T G G SE P
Sbjct: 776 VW----CLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSE----P 827
Query: 993 RITSMDARGS 1002
+ +DA G+
Sbjct: 828 QFIQLDAHGN 837
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,634,011
Number of Sequences: 37866
Number of extensions: 1978274
Number of successful extensions: 15126
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 275
Number of HSP's successfully gapped in prelim test: 263
Number of HSP's that attempted gapping in prelim test: 4343
Number of HSP's gapped (non-prelim): 4068
length of query: 1028
length of database: 18,247,518
effective HSP length: 112
effective length of query: 916
effective length of database: 14,006,526
effective search space: 12829977816
effective search space used: 12829977816
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.