Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 75677376
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|75677376 coiled-coil domain containing 62 isoform b [Homo
sapiens]
(684 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|75677376 coiled-coil domain containing 62 isoform b [Homo sap... 1352 0.0
gi|30348972 coiled-coil domain containing 62 isoform a [Homo sap... 1321 0.0
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 80 6e-15
gi|71061468 centromere protein E [Homo sapiens] 75 2e-13
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 74 3e-13
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 74 6e-13
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 74 6e-13
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 74 6e-13
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 74 6e-13
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 73 8e-13
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 73 1e-12
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 73 1e-12
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 71 3e-12
gi|187761324 shootin1 isoform a [Homo sapiens] 70 8e-12
gi|50511340 shootin1 isoform b [Homo sapiens] 70 8e-12
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 69 1e-11
gi|188528616 testis specific, 10 [Homo sapiens] 69 1e-11
gi|13376858 testis specific, 10 [Homo sapiens] 69 1e-11
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 69 2e-11
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho... 68 3e-11
gi|32698688 citron [Homo sapiens] 68 3e-11
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 67 5e-11
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 67 7e-11
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom... 67 7e-11
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom... 67 7e-11
gi|42794779 myosin 18A isoform b [Homo sapiens] 67 7e-11
gi|28416946 myosin 18A isoform a [Homo sapiens] 67 7e-11
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 66 1e-10
gi|38044112 restin isoform b [Homo sapiens] 65 2e-10
gi|4506751 restin isoform a [Homo sapiens] 65 2e-10
>gi|75677376 coiled-coil domain containing 62 isoform b [Homo
sapiens]
Length = 684
Score = 1352 bits (3500), Expect = 0.0
Identities = 684/684 (100%), Positives = 684/684 (100%)
Query: 1 MNPPAAFLAGRQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEE 60
MNPPAAFLAGRQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEE
Sbjct: 1 MNPPAAFLAGRQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEE 60
Query: 61 DRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQK 120
DRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQK
Sbjct: 61 DRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQK 120
Query: 121 ATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADC 180
ATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADC
Sbjct: 121 ATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADC 180
Query: 181 SGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEI 240
SGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEI
Sbjct: 181 SGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEI 240
Query: 241 IRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLN 300
IRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLN
Sbjct: 241 IRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLN 300
Query: 301 FNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEA 360
FNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEA
Sbjct: 301 FNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEA 360
Query: 361 MLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSIFTKDLVEKHNLPWSLGGKTQIE 420
MLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSIFTKDLVEKHNLPWSLGGKTQIE
Sbjct: 361 MLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSIFTKDLVEKHNLPWSLGGKTQIE 420
Query: 421 PENKITLCKIHTKSPKCHGTGVQNEGKQPSETPTLSDEKQWHDVSVYLGLTNCPSSKHPE 480
PENKITLCKIHTKSPKCHGTGVQNEGKQPSETPTLSDEKQWHDVSVYLGLTNCPSSKHPE
Sbjct: 421 PENKITLCKIHTKSPKCHGTGVQNEGKQPSETPTLSDEKQWHDVSVYLGLTNCPSSKHPE 480
Query: 481 KLDVECQDQMERSEISCCQKNEACLGESGMCDSKCCHPSNFIIEAPGHMSDVEWMSIFKP 540
KLDVECQDQMERSEISCCQKNEACLGESGMCDSKCCHPSNFIIEAPGHMSDVEWMSIFKP
Sbjct: 481 KLDVECQDQMERSEISCCQKNEACLGESGMCDSKCCHPSNFIIEAPGHMSDVEWMSIFKP 540
Query: 541 SKMQRIVRLKSGCTCSESICGTQHDSPASELIAIQDSHSLGSSKSALREDETESSSNKKN 600
SKMQRIVRLKSGCTCSESICGTQHDSPASELIAIQDSHSLGSSKSALREDETESSSNKKN
Sbjct: 541 SKMQRIVRLKSGCTCSESICGTQHDSPASELIAIQDSHSLGSSKSALREDETESSSNKKN 600
Query: 601 SPTSLLIYKDAPAFNEKASIVLPSQDDFSPTSKLQRLLAESRQMVTDLELSTLLPISHEN 660
SPTSLLIYKDAPAFNEKASIVLPSQDDFSPTSKLQRLLAESRQMVTDLELSTLLPISHEN
Sbjct: 601 SPTSLLIYKDAPAFNEKASIVLPSQDDFSPTSKLQRLLAESRQMVTDLELSTLLPISHEN 660
Query: 661 LTGSATNKSEVPEESAQKNTFVSY 684
LTGSATNKSEVPEESAQKNTFVSY
Sbjct: 661 LTGSATNKSEVPEESAQKNTFVSY 684
>gi|30348972 coiled-coil domain containing 62 isoform a [Homo
sapiens]
Length = 682
Score = 1321 bits (3419), Expect = 0.0
Identities = 671/681 (98%), Positives = 673/681 (98%), Gaps = 1/681 (0%)
Query: 1 MNPPAAFLAGRQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEE 60
MNPPAAFLAGRQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEE
Sbjct: 1 MNPPAAFLAGRQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEE 60
Query: 61 DRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQK 120
DRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQK
Sbjct: 61 DRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQK 120
Query: 121 ATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADC 180
ATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADC
Sbjct: 121 ATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADC 180
Query: 181 SGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEI 240
SGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEI
Sbjct: 181 SGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEI 240
Query: 241 IRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLN 300
IRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLN
Sbjct: 241 IRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLN 300
Query: 301 FNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEA 360
FNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEA
Sbjct: 301 FNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEA 360
Query: 361 MLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSIFTKDLVEKHNLPWSLGGKTQIE 420
MLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSIFTKDLVEKHNLPWSLGGKTQIE
Sbjct: 361 MLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSIFTKDLVEKHNLPWSLGGKTQIE 420
Query: 421 PENKITLCKIHTKSPKCHGTGVQNEGKQPSETPTLSDEKQWHDVSVYLGLTNCPSSKHPE 480
PENKITLCKIHTKSPKCHGTGVQNEGKQPSETPTLSDEKQWHDVSVYLGLTNCPSSKHPE
Sbjct: 421 PENKITLCKIHTKSPKCHGTGVQNEGKQPSETPTLSDEKQWHDVSVYLGLTNCPSSKHPE 480
Query: 481 KLDVECQDQMERSEISCCQKNEACLGESGMCDSKCCHPSNFIIEAPGHMSDVEWMSIFKP 540
KLDVECQDQMERSEISCCQKNEACLGESGMCDSKCCHPSNFIIEAPGHMSDVEWMSIFKP
Sbjct: 481 KLDVECQDQMERSEISCCQKNEACLGESGMCDSKCCHPSNFIIEAPGHMSDVEWMSIFKP 540
Query: 541 SKMQRIVRLKSGCTCSESICGTQHDSPASELIAIQDSHSLGSSKSALREDETESSSNKKN 600
SKMQRIVRLKSGCTCSESICGTQHDSPASELIAIQDSHSLGSSKSALREDETESSSNKKN
Sbjct: 541 SKMQRIVRLKSGCTCSESICGTQHDSPASELIAIQDSHSLGSSKSALREDETESSSNKKN 600
Query: 601 SPTSLLIYKDAPAFNEKASIVLPSQDDFSPTSKLQRLLAESRQMVTDLELSTLLPISHEN 660
SPTSLLIYKDAPAFNEKASIVLPSQDDFSPTSKLQRLLAESRQMVTDLELSTLLPISHEN
Sbjct: 601 SPTSLLIYKDAPAFNEKASIVLPSQDDFSPTSKLQRLLAESRQMVTDLELSTLLPISHEN 660
Query: 661 LTGSATNKSEV-PEESAQKNT 680
LTGSATN S + + A NT
Sbjct: 661 LTGSATNISHLCGRQKADTNT 681
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 80.1 bits (196), Expect = 6e-15
Identities = 82/391 (20%), Positives = 167/391 (42%), Gaps = 26/391 (6%)
Query: 11 RQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQL--LSWEEDRQKVLT- 67
++ +E ++ + ++ L I +L K L + HQQ L L EED+ LT
Sbjct: 970 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQE---AHQQTLDDLQMEEDKVNTLTK 1026
Query: 68 ----LEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATH 123
LE++ LEG L + ++ L + + LE + Q + T+ Q++ +K
Sbjct: 1027 AKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKK 1086
Query: 124 SSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGK 183
+L+ + E ++L ++ +LQAR + L I+ + +A +D S +
Sbjct: 1087 KEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRE 1146
Query: 184 FKMLEHALRDA-----------KMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTE 232
+ + L +A K E K ++D ++ + L++ + E
Sbjct: 1147 LEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAE 1206
Query: 233 NNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHN-LRQIYVK 291
EQ + + R+KQ+ EL + E ++ AK+ E+ L + L +I K
Sbjct: 1207 LGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTK 1266
Query: 292 QQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKS 351
++ + +N E S + +++ E S+ LD +D +S L + E+ ++
Sbjct: 1267 EEEQQRLIN---ELSAQKARLHTESGEFSRQLD-EKDAMVSQLSRGKQAFTQQIEELKRQ 1322
Query: 352 LFKDQKFEAMLVQQNRSDKSSCDECKEKKQQ 382
L ++ K ++ L +S + CD +E+ ++
Sbjct: 1323 LEEETKAKSTLAHALQSARHDCDLLREQYEE 1353
Score = 50.8 bits (120), Expect = 4e-06
Identities = 65/293 (22%), Positives = 125/293 (42%), Gaps = 43/293 (14%)
Query: 55 LLSWEEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKAL--ESNQMECQT------- 105
LL E +++ ++E K + EL K + L +K+ L E N ++ Q
Sbjct: 843 LLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADAL 902
Query: 106 --------ALQKTQLQLQ----EMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQ 153
L KT++QL+ E+ ++A ++ +L A+ L + EL + L+
Sbjct: 903 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
Query: 154 ---AREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQ 210
A+ + + K K++ E + + + K + AL++A ++Q
Sbjct: 963 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEA-------------HQQ 1009
Query: 211 KLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDE-LLN 269
L L++E +K+ KT + + L+QEK +L +ER KRK E L
Sbjct: 1010 TLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEK-----KLCMDLERAKRKLEGDLK 1064
Query: 270 IAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKA 322
+A+ T ++ L + K++ ++ L +E+ Q L K++E +A
Sbjct: 1065 LAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQA 1117
Score = 50.1 bits (118), Expect = 7e-06
Identities = 73/343 (21%), Positives = 142/343 (41%), Gaps = 50/343 (14%)
Query: 69 EERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLS 128
E+ + ++ E K E + K K LE + QLQ+Q A
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALA------ 903
Query: 129 EDLEARNETLSNTLVELSAQVGQLQAR---EQALTTMIKLKDKDIIEAVNHIADCSGKFK 185
D E R + L T ++L A++ ++ R E+ + + K + + + +CS
Sbjct: 904 -DAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLED------ECSE--- 953
Query: 186 MLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNE---------- 235
L+ + D ++ + KEK + K+K L E+ L E + + T E
Sbjct: 954 -LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLD 1012
Query: 236 ----QREEIIRLKQEKSCLH---DELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQI 288
+ +++ L + K+ L D+L ++E+EK+ L AK K E +L ++
Sbjct: 1013 DLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLE---GDLKLAQES 1069
Query: 289 YVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKN 348
+ ++D Q LN ++ + + K+E+ +AL + +L+ +++ + E
Sbjct: 1070 TMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAE 1129
Query: 349 QKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKS 391
+ S K +K RSD S E +E ++++ G S
Sbjct: 1130 RASRAKAEK--------QRSDLSR--ELEEISERLEEAGGATS 1162
Score = 48.9 bits (115), Expect = 2e-05
Identities = 76/356 (21%), Positives = 150/356 (42%), Gaps = 39/356 (10%)
Query: 42 KELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQM 101
K+ D VA +Q+ S + +QK LE+ S+L+ E++ + +++K E
Sbjct: 1198 KKHADSVAELGEQIDSLQRVKQK---LEKEKSELKMEINDLASNMETVSKAKANFEKMCR 1254
Query: 102 ECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTT 161
+ L + + + +E + S L + S L E A V QL +QA T
Sbjct: 1255 TLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQ 1314
Query: 162 MIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNK 221
I+ E + + + L HAL+ A+ + +++E+ + +Q+ KA +
Sbjct: 1315 QIE-------ELKRQLEEETKAKSTLAHALQSARH-DCDLLREQYEEEQEAKA------E 1360
Query: 222 LKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDEL---LNIAKSKQERT 278
L+ +++ +E + R K E D + T E E+ K +L L A+ E
Sbjct: 1361 LQRGMSKANSEVAQWRT-----KYET----DAIQRTEELEEAKKKLAQRLQDAEEHVEAV 1411
Query: 279 NSELHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNH 338
NS+ +L + + Q++++ L +VE S D K + D L++ + +
Sbjct: 1412 NSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQR-------NFDKVLAEWKQKY 1464
Query: 339 PKVDIKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVIT 394
+ + E +QK + + L + + + S D + K++ + E S +T
Sbjct: 1465 EETQAELEASQK---ESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLT 1517
Score = 46.2 bits (108), Expect = 1e-04
Identities = 78/413 (18%), Positives = 167/413 (40%), Gaps = 48/413 (11%)
Query: 25 KQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGELHKRTE 84
++ +EL+ +L R ++ + V + S E+ +Q+ L+ L ++ +
Sbjct: 1385 QRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQR---LQNEVEDLMIDVERSNA 1441
Query: 85 IIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNETLSNTLVE 144
+L KK + + E + ++TQ +L E +QK + S LS +L +L
Sbjct: 1442 ACIALDKKQRNFDKVLAEWKQKYEETQAEL-EASQKESRS--LSTELFKVKNAYEESLDH 1498
Query: 145 LSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMAETCIVKE 204
L L+ + L I + I E HI + K L+H + + +
Sbjct: 1499 LET----LKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEAS 1554
Query: 205 KQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKR- 263
+ + K+ +++E+N++K +++ K E + EE+ +LK+ + + + T++ E R
Sbjct: 1555 LEHEEGKILRIQLELNQVKSEIDRKIAEKD---EELDQLKRNHLRVVESMQSTLDAEIRS 1611
Query: 264 KDELLNIAKSKQERTN--------------SELHNLRQIY-------------VKQQSDL 296
+++ L I K + N L NLR ++ Q DL
Sbjct: 1612 RNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDL 1671
Query: 297 QFLNFNVENSQELIQMYDSKMEES-KALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKD 355
+ VE L+Q ++ S + + R M +L + +V + +N +
Sbjct: 1672 KEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTK 1731
Query: 356 QKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSIFTKDLVEKHN 408
+K E + Q + E + +++ K IT +++ ++L ++ +
Sbjct: 1732 KKLETDISQIQGEMEDIVQEARNAEEK------AKKAITDAAMMAEELKKEQD 1778
Score = 36.6 bits (83), Expect = 0.079
Identities = 39/214 (18%), Positives = 89/214 (41%), Gaps = 14/214 (6%)
Query: 17 EVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLE 76
E +IS I+ + +++ +++ K+ A+ ++L ++ + +++ +
Sbjct: 1735 ETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTV 1794
Query: 77 GELHKRTEIIRSLT-----KKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDL 131
+L R + L K+++ LE+ E ++ ++ Q E + ++L
Sbjct: 1795 KDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKEL 1854
Query: 132 EARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHAL 191
+ E ++ L V +LQ T +K + EA KF+ L+H L
Sbjct: 1855 TYQTEEDRKNILRLQDLVDKLQ-------TKVKAYKRQAEEAEEQSNVNLAKFRKLQHEL 1907
Query: 192 RDAKMAETCIVKEKQDYKQKLKALKIEVNKLKED 225
+AK E + E Q K ++K+ ++ + E+
Sbjct: 1908 EEAK--ERADIAESQVNKLRVKSREVHTKVISEE 1939
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 75.5 bits (184), Expect = 2e-13
Identities = 98/432 (22%), Positives = 184/432 (42%), Gaps = 65/432 (15%)
Query: 19 EISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGE 78
E + + + EL+ + EL K++ + + ++Q QL E ++ + LE+ E
Sbjct: 640 ESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQL---EAKKKMQVDLEKELQSAFNE 696
Query: 79 LHKRTEIIRS-----------LTKKVKALE---SNQMECQTALQKTQLQLQEMAQKATHS 124
+ K T +I L K+ L+ + ++E AL++ + L E+ +
Sbjct: 697 ITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEV 756
Query: 125 SLLSEDLEARNETLSNTLVE---LSAQVGQLQAREQALTTMI-KLKDKDIIEAVNHIA-- 178
L ++++ ++E L E L ++V ++R Q L I K KD N+ +
Sbjct: 757 ERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTD 816
Query: 179 -----------DCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLN 227
D K+KM+ + KE Q + L ALK E++ ++L
Sbjct: 817 QEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQ 876
Query: 228 EKTTENNEQREEIIRLKQEKSCLHDELLFTVEREK-------------------RKDELL 268
EKT E E+ E+ +LK++ D L TVEREK KD+L
Sbjct: 877 EKTREVQERLNEMEQLKEQLE-NRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLK 935
Query: 269 NIAKSKQ---ERTNSELHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKA--- 322
+ +S Q ++ S++H+ + + Q L+ +++ QE I SK+ E +
Sbjct: 936 QLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNL 995
Query: 323 -LDSSRDMCLSDLENNHPKVDIKRE---KNQKSLFKDQKFEAMLVQQNRSDKSSCDECKE 378
++ + + + +D K++ KN ++L D K + +++Q R S E E
Sbjct: 996 HMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVK-DNEIIEQQRKIFSLIQEKNE 1054
Query: 379 KKQQIDTVFGEK 390
+Q +++V EK
Sbjct: 1055 LQQMLESVIAEK 1066
Score = 72.8 bits (177), Expect = 1e-12
Identities = 88/403 (21%), Positives = 188/403 (46%), Gaps = 51/403 (12%)
Query: 17 EVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLE 76
E EISTI+KQ L+ + +L+++ +E+ + +E++ + + E K+
Sbjct: 1504 ETEISTIQKQ---LEAINDKLQNKIQEIYE------------KEEQFNIKQISEVQEKVN 1548
Query: 77 GELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNE 136
EL + E ++ ++++ES +E LQ++Q ++Q M ++ + E L+ +
Sbjct: 1549 -ELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERD 1607
Query: 137 TLSNTLVELSAQVGQLQAREQALTTMIKLKD-KDIIEAVNHIADCSGKFKM--------- 186
L E+ A++ + Q +E M + + ++ + + H+ + K+
Sbjct: 1608 QLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETEN 1667
Query: 187 --LEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEI---- 240
L L + + KE+ D + + LK+E ++LKE+L E T + E++EE+
Sbjct: 1668 IRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVH 1727
Query: 241 IRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLN 300
+ LK+ + + D+L V ++ +E+ N+ K + ++ L+ +K Q +L+ +
Sbjct: 1728 MHLKEHQETI-DKLRGIV--SEKTNEISNMQKDLEHSNDA----LKAQDLKIQEELRIAH 1780
Query: 301 FNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEA 360
+++ QE I + E D +M DLEN++ K+ +EK Q+ + +
Sbjct: 1781 MHLKEQQETIDKLRGIVSEK--TDKLSNM-QKDLENSNAKL---QEKIQELKANEHQLIT 1834
Query: 361 MLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSIFTKDL 403
+ N + K E ++ K+QI + +TLS + ++L
Sbjct: 1835 LKKDVNETQK-KVSEMEQLKKQI-----KDQSLTLSKLEIENL 1871
Score = 67.8 bits (164), Expect = 3e-11
Identities = 79/387 (20%), Positives = 169/387 (43%), Gaps = 48/387 (12%)
Query: 19 EISTIEKQRKELQLLIGELKDRDK-----------ELNDMVAVHQQQLLSWEEDRQKVLT 67
E+S ++ EL+LL + +D LN+ Q+++ S ++R + T
Sbjct: 1297 EVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKT 1356
Query: 68 LEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLL 127
++E LE + + E IR K++ +S Q + L ++E + T
Sbjct: 1357 IKEA---LEVKHDQLKEHIRETLAKIQESQSKQEQ--------SLNMKEKDNETTKIVSE 1405
Query: 128 SEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKML 187
E + ++ L +E+ +LQ + ++ K +KD ++ + + L
Sbjct: 1406 MEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAK--EKDDLQRLQEVLQSESD--QL 1461
Query: 188 EHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEK 247
+ +++ IV + + +++LK + + +E +NE +E+ EI ++++
Sbjct: 1462 KENIKE-------IVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQL 1514
Query: 248 SCLHDELLFTVEREKRKDELLNIAK--SKQERTNSELHNLRQIYVKQQSDLQF------- 298
++D+L ++ K+E NI + QE+ N EL ++ + S LQ
Sbjct: 1515 EAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVN-ELKQFKEHRKAKDSALQSIESKMLE 1573
Query: 299 LNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKF 358
L ++ SQE IQ+ + EE K + + + L+ N ++ K +++Q+ ++ K
Sbjct: 1574 LTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKM 1633
Query: 359 EAMLVQQNRSDKSSCDECKEKKQQIDT 385
A+ N + + C E + K+Q +T
Sbjct: 1634 TAV----NETQEKMC-EIEHLKEQFET 1655
Score = 56.6 bits (135), Expect = 7e-08
Identities = 67/336 (19%), Positives = 158/336 (47%), Gaps = 38/336 (11%)
Query: 23 IEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTL----EERCSKLEGE 78
I +K+L+ LK +D ++ + + + L +E K+ + ++ S ++ +
Sbjct: 1751 ISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKD 1810
Query: 79 LHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNETL 138
L ++ +++KA E + + + +TQ ++ EM Q L + ++ ++ TL
Sbjct: 1811 LENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQ-------LKKQIKDQSLTL 1863
Query: 139 SNTLVELSAQVGQLQAREQALTTMIKLKD--KDIIEAVNHIADCSGKFKMLEHALRDAKM 196
S +E +L + + +++K +D + + E + D L+ +L++ K
Sbjct: 1864 SKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERD------QLKESLQETKA 1917
Query: 197 AETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLF 256
+ I +E + + K K V+KL+E ++EKT + ++ ++++ + K DEL
Sbjct: 1918 RDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSK-------DELQK 1970
Query: 257 TVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNF---NVENSQELIQMY 313
++ ++K+ L K ++ +++ + Q+ K+Q + Q L+ ++N Q +++
Sbjct: 1971 KIQELQKKELQLLRVKEDVNMSHKKINEMEQL--KKQFEAQNLSMQSVRMDNFQLTKKLH 2028
Query: 314 DSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQ 349
+S +EE + + RD E K +K E++Q
Sbjct: 2029 ES-LEEIRIVAKERD------ELRRIKESLKMERDQ 2057
Score = 55.8 bits (133), Expect = 1e-07
Identities = 77/368 (20%), Positives = 162/368 (44%), Gaps = 35/368 (9%)
Query: 14 IGSEVEISTIEKQRKELQLLIG-------ELKDRDKELNDMVAVHQQQL--LSWEEDRQK 64
I + +I ++ +++ ELQ ++ +LK KE +M +Q++L L E +Q+
Sbjct: 1039 IEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQ 1098
Query: 65 VLTLEER--CSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKAT 122
+ +E+ K EGEL + + + + +K+K E Q L Q ++ EM +K
Sbjct: 1099 EIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKIN 1158
Query: 123 HSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSG 182
L +L+ + TL + E +L + + ++ K++ +++ + +
Sbjct: 1159 EIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSI--TKERKVLKELQKSFETE- 1215
Query: 183 KFKMLEHALRDAKMAETCIVKEKQDYK---QKLKALKIEVNKLKEDLNEKTTE--NNEQR 237
+H + E ++ K++ K LK + +++L+ ++EKT + N +
Sbjct: 1216 ----RDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDL 1271
Query: 238 EEI-IRLKQEKSCLHD--ELLFTVEREKRKDELLN-IAKSKQERTNSELHNLRQIYVKQQ 293
E+ +L++E LH+ ELL V+ E +N + ++ T + L +I +++
Sbjct: 1272 EKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERL 1331
Query: 294 SDLQFLNFNVENSQELIQMYDSKMEESK----ALDSSRDMCLSDLENNHPKVDIKREKNQ 349
LN + SQE I+ + + K AL+ D + K+ + K +
Sbjct: 1332 R----LNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQE 1387
Query: 350 KSLFKDQK 357
+SL +K
Sbjct: 1388 QSLNMKEK 1395
Score = 54.3 bits (129), Expect = 4e-07
Identities = 58/323 (17%), Positives = 147/323 (45%), Gaps = 39/323 (12%)
Query: 22 TIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGELHK 81
TI+K R + +L + K+L + A Q+++ + + +++TL++ ++ + ++ +
Sbjct: 1789 TIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSE 1848
Query: 82 RTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEM---AQKATHSSLLSEDLEARNETL 138
++ + + + L ++E QK L+EM ++ + + E L+ + L
Sbjct: 1849 MEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQL 1908
Query: 139 SNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMAE 198
+L E A+ ++Q +E M+ + K+ ++ + K++E
Sbjct: 1909 KESLQETKARDLEIQ-QELKTARMLSKEHKETVDKLRE------------------KISE 1949
Query: 199 TCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTV 258
I ++ ++ +++K K++L +K E ++ +++R+K++ + H + + +
Sbjct: 1950 KTI---------QISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKK-INEM 1999
Query: 259 EREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDS-KM 317
E+ K++ E N++ N +L K L+ + + EL ++ +S KM
Sbjct: 2000 EQLKKQFEAQNLSMQSVRMDNFQLTK------KLHESLEEIRIVAKERDELRRIKESLKM 2053
Query: 318 EESKALDSSRDMCLSDLENNHPK 340
E + + + R+M D +N+ K
Sbjct: 2054 ERDQFIATLREMIARDRQNHQVK 2076
Score = 45.4 bits (106), Expect = 2e-04
Identities = 84/366 (22%), Positives = 156/366 (42%), Gaps = 63/366 (17%)
Query: 92 KVKALESNQMECQTALQKTQLQLQEMAQKATHSSL--LSEDLEARNETLSNTLVELSAQV 149
++K E N ++ AL++ + QEM S+L L + E N+ L N ELS++V
Sbjct: 525 ELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLEN---ELSSKV 581
Query: 150 GQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALR-------------DAKM 196
L+ +E + + + D +E + D S + +E + DAK
Sbjct: 582 ELLREKEDQIKKLQEYIDSQKLENIK--MDLSYSLESIEDPKQMKQTLFDAETVALDAKR 639
Query: 197 AETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDE--- 253
+ E + K+K+K L +++ D+ ++ +++ + L++E +E
Sbjct: 640 ESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITK 699
Query: 254 LLFTVEREKRKDELLNI-----AKSKQERTNSELHN---LRQIYVKQQSDLQFLNFNVEN 305
L ++ + KD L N+ Q+ N E+ LR+ V S+L+ L VE
Sbjct: 700 LTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALRE-EVILLSELKSLPSEVER 758
Query: 306 SQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKV-----DIKREK------------- 347
++ IQ K EE + S +D S++ + +V +I + K
Sbjct: 759 LRKEIQ---DKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKST 815
Query: 348 -----NQKSLFKD--QKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSIFT 400
N K+L D QK++ +L + R ++ + KE Q+ D+ G ++ T S T
Sbjct: 816 DQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKE-AQKFDSSLG--ALKTELSYKT 872
Query: 401 KDLVEK 406
++L EK
Sbjct: 873 QELQEK 878
Score = 39.7 bits (91), Expect = 0.009
Identities = 99/464 (21%), Positives = 193/464 (41%), Gaps = 69/464 (14%)
Query: 20 ISTIEKQRKELQLLIGELKD---------RDKELNDMVAVHQQQLL---------SWEED 61
I +EKQ KEL + I L+ RD +LN + +H +++L S + +
Sbjct: 2199 IDEVEKQ-KELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTE 2257
Query: 62 RQKVLTLEERCSK-LEGELHKRTEIIRSLTKKVKALESNQMECQT---------ALQKTQ 111
Q+VL+ + ++ LE L+ R +I + K + N CQ A+
Sbjct: 2258 FQQVLSNRKEMTQFLEEWLNTRFDIEKL---KNGIQKENDRICQVNNFFNNRIIAIMNES 2314
Query: 112 LQLQEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDII 171
+ +E + AT S +DL++ E L + Q T K+ +
Sbjct: 2315 TEFEE--RSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVT 2372
Query: 172 EAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTT 231
+ + K + LE++L +AK E+ + KE + K + K L++ N + L K
Sbjct: 2373 SRATQLT--TEKIRELENSLHEAK--ESAMHKESKIIKMQ-KELEV-TNDIIAKLQAKVH 2426
Query: 232 ENN---EQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQI 288
E+N E+ +E I++ Q+K L + +E+ +D + + K E+ + N ++
Sbjct: 2427 ESNKCLEKTKETIQVLQDKVALGAKPY----KEEIEDLKMKLVKIDLEK----MKNAKEF 2478
Query: 289 YVKQQSDLQFLNFNVENSQELIQMYDSKMEESK-ALDSSRDMCLSDLENNHPKVDIKREK 347
+ ++ VE +E+I++ + S+ A D+S +S+ + P
Sbjct: 2479 ----EKEISATKATVEYQKEVIRLLRENLRRSQQAQDTS---VISEHTDPQPSNKPLTCG 2531
Query: 348 NQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSIFTKDLVEKH 407
+ ++ K + + R +K E + KQQ + + +K+ + ++ + V+
Sbjct: 2532 GGSGIVQNTKALILKSEHIRLEK----EISKLKQQNEQLIKQKNELLSNNQHLSNEVKT- 2586
Query: 408 NLPWSLGGKTQIEPENKITLCKIHTKSPKCHGTGVQNEGKQPSE 451
W +T +K C+ KSPK GT + + PS+
Sbjct: 2587 ---WK--ERTLKREAHKQVTCENSPKSPKVTGTASKKKQITPSQ 2625
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 74.3 bits (181), Expect = 3e-13
Identities = 101/501 (20%), Positives = 208/501 (41%), Gaps = 41/501 (8%)
Query: 11 RQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQL--LSWEEDRQKVLT- 67
++ +E ++ + ++ L I +L K L + HQQ L L EED+ +LT
Sbjct: 969 KEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQE---THQQTLDDLQAEEDKVNILTK 1025
Query: 68 ----LEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATH 123
LE++ LEG L + ++ L + + LE + Q + + Q++ +K
Sbjct: 1026 AKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEK 1085
Query: 124 SSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGK 183
+L ++ E ++L ++ +LQAR + L I+ + +A +D S +
Sbjct: 1086 KEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRE 1145
Query: 184 FKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRL 243
+ + L +A A + V+ K + E KL+ DL E T ++ + L
Sbjct: 1146 LEEISERLEEAGGATSAQVELN-------KKREAEFQKLRRDLEEATLQHEAM---VAAL 1195
Query: 244 KQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNV 303
+++ + EL ++ +R + L KS+ + +L + + K + +L
Sbjct: 1196 RKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNL------- 1248
Query: 304 ENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLV 363
+++ + + ++ E K + + ++DL + ++ E + S D+K +A++
Sbjct: 1249 ---EKMCRSLEDQVSELKTKEEEQQRLINDLTAQRAR--LQTEAGEYSRQLDEK-DALVS 1302
Query: 364 QQNRSDKSSCDECKEKKQQIDTVFGEKSVIT---LSSIFTKDLVEKHNLPWSLGGKTQIE 420
Q +RS ++S + +E K Q++ K+ + SS DL+ + GK +++
Sbjct: 1303 QLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLL-REQYEEEQEGKAELQ 1361
Query: 421 PENKITLCKIHTKSPKCHGTGVQNEGKQPSETPTLSDEKQWHDVSVYLGLTNCPS-SKHP 479
++ K +Q + L+ Q + V C S K
Sbjct: 1362 RALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTK 1421
Query: 480 EKLDVECQDQM---ERSEISC 497
++L E +D M ERS +C
Sbjct: 1422 QRLQNEVEDLMLDVERSNAAC 1442
Score = 53.5 bits (127), Expect = 6e-07
Identities = 78/345 (22%), Positives = 138/345 (40%), Gaps = 56/345 (16%)
Query: 55 LLSWEEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQL 114
LL E +++ T++E K + EL K K K LE + QLQ+
Sbjct: 842 LLKSAETEKEMATMKEEFQKTKDELAKS-------EAKRKELEEKMVTLLKEKNDLQLQV 894
Query: 115 QEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAR---EQALTTMIKLKDKDII 171
Q A D E R E L ++L A++ ++ R E+ + + K + +
Sbjct: 895 QSEADSLA-------DAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLE 947
Query: 172 EAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTT 231
+ +CS L+ + D ++ + KEK + K+K L E+ L
Sbjct: 948 D------ECS----ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLD-------- 989
Query: 232 ENNEQREEIIRLKQEKSCL---HDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQI 288
E I +L +EK L H + L ++ E+ K +L AK+K E+ +L +
Sbjct: 990 ------ETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQ 1043
Query: 289 YVKQQSDLQFLNFNVENSQELIQMYDSKMEESK-ALDSSRDMCLSDLEN------NHPKV 341
K + DL+ +E +L Q ME K LD + ++ N + V
Sbjct: 1044 EKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAV 1103
Query: 342 DIKREKNQKSLFK-----DQKFEAMLVQQNRSDKSSCDECKEKKQ 381
+I+ +K K L ++ EA + +++K D +E ++
Sbjct: 1104 EIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEE 1148
Score = 40.4 bits (93), Expect = 0.005
Identities = 70/351 (19%), Positives = 143/351 (40%), Gaps = 36/351 (10%)
Query: 17 EVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQL-----LSWEEDRQKVLT---L 68
E ++S ++ + +E Q LI +L + L + +QL L + R K + +
Sbjct: 1256 EDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQI 1315
Query: 69 EERCSKLEGELHKRTEIIRSLT----------KKVKALESNQMECQTALQKTQLQLQEMA 118
EE +LE E + + +L ++ + + + E Q AL K ++ +
Sbjct: 1316 EELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWR 1375
Query: 119 QK-ATHSSLLSEDLEARNETLSNTLVE-------LSAQVGQLQAREQALTTMIKLKDKDI 170
K T + +E+LE + L+ L E ++A+ L+ +Q L ++ D+
Sbjct: 1376 TKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDV 1435
Query: 171 IEAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKT 230
+ A K + + L + K E + +++ ++L E+ K+K E
Sbjct: 1436 ERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESL 1495
Query: 231 TENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYV 290
+ R E L+QE S L +++ E K+ EL I K ++ E ++
Sbjct: 1496 DQLETLRRENKNLQQEISDLTEQI---AEGGKQIHELEKIKKQVEQ----EKCEIQAALE 1548
Query: 291 KQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKV 341
+ ++ L+ + Q + S+++ A +D + L+ NH +V
Sbjct: 1549 EAEASLEHEEGKILRIQLELNQVKSEVDRKIA---EKDEEIDQLKRNHTRV 1596
Score = 32.7 bits (73), Expect = 1.1
Identities = 24/111 (21%), Positives = 54/111 (48%), Gaps = 11/111 (9%)
Query: 15 GSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQL----LSWEEDRQKVLTLEE 70
G + +I +E + +EL+ + + R+ E + H++++ EEDR+ VL L++
Sbjct: 1810 GGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQD 1869
Query: 71 RCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKA 121
KL+ + ++S ++ + E + +K Q +L+E ++A
Sbjct: 1870 LVDKLQAK-------VKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERA 1913
Score = 32.3 bits (72), Expect = 1.5
Identities = 39/203 (19%), Positives = 88/203 (43%), Gaps = 17/203 (8%)
Query: 23 IEKQRKELQLLIGELKDRDKELNDMV--AVHQQQLLSWEEDRQKVL-----TLEERCSKL 75
+ + + E++ +I E ++ +++ + A + L E+D L LE+ L
Sbjct: 1737 VSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDL 1796
Query: 76 EGELHKRTEI-IRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEAR 134
+ L + ++ ++ K+++ LE+ E + ++ Q + E + ++L +
Sbjct: 1797 QHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQ 1856
Query: 135 NETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDA 194
E ++ L V +LQA+ +K + EA KF+ L+H L +A
Sbjct: 1857 TEEDRKNVLRLQDLVDKLQAK-------VKSYKRQAEEAEEQSNANLSKFRKLQHELEEA 1909
Query: 195 KMAETCIVKEKQDYKQKLKALKI 217
+ E + E Q K ++K+ ++
Sbjct: 1910 E--ERADIAESQVNKLRVKSREV 1930
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 73.6 bits (179), Expect = 6e-13
Identities = 96/429 (22%), Positives = 176/429 (41%), Gaps = 46/429 (10%)
Query: 11 RQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEE 70
+Q + E ++ E R++LQL + + K+L D + V Q ++R+ LEE
Sbjct: 950 QQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERK---LLEE 1006
Query: 71 RCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSED 130
R S L L + E ++LTK ES E + L+K + QE+ + L
Sbjct: 1007 RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEK-------LKRK 1059
Query: 131 LEARNETLSNTLVELSAQVG----QLQAREQALTTMIKLKDKDIIE---AVNHIADCSGK 183
LE + +L AQ+ QL +E+ L + D +I + A+ I + G
Sbjct: 1060 LEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH 1119
Query: 184 FKMLEHALRDAKMAETCIVKEKQDYKQKLKALKI---------------------EVNKL 222
L+ L + A K+K+D ++L+ALK EV L
Sbjct: 1120 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVL 1179
Query: 223 KEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSEL 282
K+ L+E+T + Q +E ++Q+ + +EL +E+ KR L+ K E+ N++L
Sbjct: 1180 KKALDEETRSHEAQVQE---MRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADL 1236
Query: 283 HNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVD 342
++ + + +++ +E +Q SK + + + + + L+N V
Sbjct: 1237 AGELRVLGQAKQEVEHKKKKLEAQ---VQELQSKCSDGERARAELNDKVHKLQNEVESVT 1293
Query: 343 IKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFG--EKSVITLSSIFT 400
+ + K K A L Q + + E +K + T E+ +L
Sbjct: 1294 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1353
Query: 401 KDLVEKHNL 409
+++ K NL
Sbjct: 1354 EEMEAKQNL 1362
Score = 60.8 bits (146), Expect = 4e-09
Identities = 94/432 (21%), Positives = 184/432 (42%), Gaps = 71/432 (16%)
Query: 8 LAGRQNIGSE-------VEISTIEKQRKELQLLIG-----ELKDRDKELNDMVAVHQQQL 55
LA +NI S+ E EK+ K L L E K+ + N M+ + L
Sbjct: 1457 LAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1516
Query: 56 LSWEEDRQK-VLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQL 114
+S ++D K V LE+ LE ++ + + L +++A E ++ + +Q + Q
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1576
Query: 115 QEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQA------REQALTTMIK---- 164
+ DL+AR+E +L Q+ + + +++AL K
Sbjct: 1577 ER-------------DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1623
Query: 165 --LKDKDII---------EAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLK 213
LKD ++ EA+ + + K + L DA+ + I ++ ++K K
Sbjct: 1624 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1683
Query: 214 ALKIEVNKLKEDL-------NEKTTENNEQREEIIRLKQEKSCLHDE----------LLF 256
+L+ ++ +L+EDL + E E EE+ ++ L DE L
Sbjct: 1684 SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEE 1743
Query: 257 TVEREKRKDELLN--IAKSKQ--ERTNSELHNLRQIYVKQQSDLQFL-NFNVENSQELIQ 311
+E E+ E ++ + K+ Q E+ ++EL R K +S Q L N E +L +
Sbjct: 1744 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1803
Query: 312 MYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSL-FKDQKFEAMLVQQNRSDK 370
M + + K+ ++ + ++ LE + +++ KSL KD+K + +L+Q ++
Sbjct: 1804 MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQV-EDER 1862
Query: 371 SSCDECKEKKQQ 382
++ KE+ ++
Sbjct: 1863 KMAEQYKEQAEK 1874
Score = 53.1 bits (126), Expect = 8e-07
Identities = 72/360 (20%), Positives = 147/360 (40%), Gaps = 43/360 (11%)
Query: 36 ELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKA 95
E++ ++ EL Q+ +E QK L E + L+ +L TE+
Sbjct: 853 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY--------- 903
Query: 96 LESNQMECQTALQKTQLQ--LQEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQ 153
E+ +M + A +K +L+ L EM + + L+A + ++ +++L Q+ + +
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 154 AREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLK 213
A Q L +E V K K LE + + KE++ ++++
Sbjct: 964 AARQKLQ----------LEKVT----AEAKIKKLEDEILVMDDQNNKLSKERKLLEERI- 1008
Query: 214 ALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKS 273
DL E E+ + + +LK + + EL +++E++ + L K
Sbjct: 1009 ----------SDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1058
Query: 274 KQERTNSELHNLRQIYVKQQSDL--QFLNFNVENSQELIQMYDSKMEESKALDSSRDM-- 329
K E S+ H Q ++L Q E L ++ D +++ AL R++
Sbjct: 1059 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1118
Query: 330 CLSDLE---NNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTV 386
+SDL+ ++ K EK ++ L ++ + ++ ++ E + K++Q TV
Sbjct: 1119 HISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTV 1178
Score = 50.8 bits (120), Expect = 4e-06
Identities = 80/391 (20%), Positives = 166/391 (42%), Gaps = 53/391 (13%)
Query: 22 TIEKQRKELQ---LLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLT-LEERCSKLEG 77
T+EK+ +L ++G+ K + + Q+L S D ++ L ++ KL+
Sbjct: 1228 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
Query: 78 ELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNET 137
E+ T ++ K L + + LQ TQ LQE ++ + S LE +
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
Query: 138 LSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMA 197
L + L E +++A+ Q L I + + ++ + D + + LE K
Sbjct: 1348 LQDQLDE------EMEAK-QNLERHISTLNIQLSDSKKKLQDFASTVEALEEG---KKRF 1397
Query: 198 ETCIVKEKQDYKQKLKA---LKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDEL 254
+ I Q Y++K A L+ N+L+++L++ + + QR+ + L ++K D+L
Sbjct: 1398 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNL-EKKQRKFDQL 1456
Query: 255 L---------FTVEREK-------RKDELLNIAKSKQE--RTNSELHNLRQIYVKQQSDL 296
L + ER++ ++ + L++A++ +E EL ++ + DL
Sbjct: 1457 LAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1516
Query: 297 ----QFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSL 352
+ NV ++ + +++MEE K L +LE D + L
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQ-------LEELE------DELQATEDAKL 1563
Query: 353 FKDQKFEAMLVQQNRSDKSSCDECKEKKQQI 383
+ +A+ Q R ++ ++ +EK++Q+
Sbjct: 1564 RLEVNMQALKGQFERDLQARDEQNEEKRRQL 1594
Score = 45.4 bits (106), Expect = 2e-04
Identities = 78/441 (17%), Positives = 184/441 (41%), Gaps = 36/441 (8%)
Query: 18 VEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEG 77
+++S +K+ ++ + L++ K + QQ +EE LE+ ++L+
Sbjct: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ---YEEKAAAYDKLEKTKNRLQQ 1427
Query: 78 ELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNET 137
EL + + + V LE Q + L + + + A + + + + E + +
Sbjct: 1428 ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALS 1487
Query: 138 LSNTLVELSAQVGQLQAREQALTT--MIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAK 195
L+ L E L+A+E+ T M+K + +D++ + + + + + + AL
Sbjct: 1488 LARALEEA------LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1541
Query: 196 MAETCIVKEKQDYKQKLK--ALKIEVN------KLKEDLNEKTTENNEQREEIIR-LKQE 246
++E +D Q + L++EVN + + DL + +N E+R ++ R L +
Sbjct: 1542 EEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEY 1601
Query: 247 KSCLHDE----LLFTVEREKRKDELLNI---AKSKQERTNSELHNLRQIYVKQQSDLQFL 299
++ L DE L ++K + +L ++ A S + + LR++ + + + L
Sbjct: 1602 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1661
Query: 300 NFNVENSQELIQMYDSKMEESKALDSSRDMCLSDL---ENNHPKVDIKREKNQKSLFKDQ 356
+ E+ +++K+L++ DL E + D+++E+ + L
Sbjct: 1662 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1721
Query: 357 KFEAMLVQQNRSDKSSC----DECKEKKQQIDTVFG--EKSVITLSSIFTKDLVEKHNLP 410
L + R ++ +E +E++ ++ + K+ + + E+
Sbjct: 1722 SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQ 1781
Query: 411 WSLGGKTQIEPENKITLCKIH 431
+ + Q+E +NK K+H
Sbjct: 1782 KNESARQQLERQNKELRSKLH 1802
Score = 44.3 bits (103), Expect = 4e-04
Identities = 85/440 (19%), Positives = 179/440 (40%), Gaps = 71/440 (16%)
Query: 17 EVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLS----WEEDRQKVLTLEERC 72
E E+ ++++++ + + EL+ + +L + + Q+QL + + E + + L +
Sbjct: 858 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 917
Query: 73 SKLEGELHK----------RTEIIRSLTKKVKA----LESNQMECQTALQKTQLQ---LQ 115
+LE LH+ R + +++ KK+ LE E + A QK QL+ +
Sbjct: 918 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 977
Query: 116 EMAQKATHSSLLSED-----------LEARNETLSNTLVE------------------LS 146
+K L+ +D LE R L+ L E +S
Sbjct: 978 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1037
Query: 147 AQVGQLQAREQALTTMIKLKDK---DIIEAVNHIADCSGKFKML-------EHALRDAKM 196
+L+ E++ + KLK K D + IAD + L E L+ A
Sbjct: 1038 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1097
Query: 197 AETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLF 256
+ +K + +K++ L+ ++ L+EDL+ + N+ ++ L +E L EL
Sbjct: 1098 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1157
Query: 257 TVE--------REKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQE 308
T++ R KR+ E+ + K+ E T S ++++ K ++ L +E +
Sbjct: 1158 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1217
Query: 309 LIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRS 368
D + + ++ L L +V+ K++K + + Q+ ++ R+
Sbjct: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV---QELQSKCSDGERA 1274
Query: 369 DKSSCDECKEKKQQIDTVFG 388
D+ + + ++++V G
Sbjct: 1275 RAELNDKVHKLQNEVESVTG 1294
Score = 33.1 bits (74), Expect = 0.87
Identities = 37/194 (19%), Positives = 84/194 (43%), Gaps = 9/194 (4%)
Query: 209 KQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELL 268
+++++A + E+ K KE + E E ++ +L +EK+ L ++L E +E+
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 269 NIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRD 328
+K++ LH + +++ Q L + + + + ++EE +A
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK-- 968
Query: 329 MCLSDLENNHPKVDIKREKNQKSLFKDQ----KFEAMLVQQNRSDKSSCDECKEKKQQID 384
LE + IK+ +++ + DQ E L+++ SD ++ +E+K +
Sbjct: 969 ---LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025
Query: 385 TVFGEKSVITLSSI 398
T K +S +
Sbjct: 1026 TKLKNKHESMISEL 1039
Score = 29.6 bits (65), Expect = 9.7
Identities = 54/308 (17%), Positives = 118/308 (38%), Gaps = 42/308 (13%)
Query: 239 EIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLR-------QIYVK 291
++ R ++E DEL T ER+++ + L + K + E + L+ ++Y +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 292 QQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKS 351
+ L + +E++ ++++EE + D + + + +D++ + ++
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEE--DRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 352 LFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVI-TLSSIFTKDLVEKHNLP 410
+ QK + V K DE Q + + E+ ++ S T +L E+
Sbjct: 964 AAR-QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA 1022
Query: 411 WSLGGKTQIEPENKITLCKIHTKSPKCHGTGVQNEGKQPSETPTL-----SDEKQWHDVS 465
+L T+++ +++ + ++ + ++ E K E L D +H+
Sbjct: 1023 KNL---TKLKNKHESMISELEVR--------LKKEEKSRQELEKLKRKLEGDASDFHEQI 1071
Query: 466 VYLGLTNCPSSKHPEKLDVECQDQMERSEISCCQKNEACLGESGMCDSKCCHPSNFIIEA 525
L K + E Q + R + QKN A I E
Sbjct: 1072 ADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNAL---------------KKIREL 1116
Query: 526 PGHMSDVE 533
GH+SD++
Sbjct: 1117 EGHISDLQ 1124
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 73.6 bits (179), Expect = 6e-13
Identities = 96/429 (22%), Positives = 176/429 (41%), Gaps = 46/429 (10%)
Query: 11 RQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEE 70
+Q + E ++ E R++LQL + + K+L D + V Q ++R+ LEE
Sbjct: 957 QQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERK---LLEE 1013
Query: 71 RCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSED 130
R S L L + E ++LTK ES E + L+K + QE+ + L
Sbjct: 1014 RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEK-------LKRK 1066
Query: 131 LEARNETLSNTLVELSAQVG----QLQAREQALTTMIKLKDKDIIE---AVNHIADCSGK 183
LE + +L AQ+ QL +E+ L + D +I + A+ I + G
Sbjct: 1067 LEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH 1126
Query: 184 FKMLEHALRDAKMAETCIVKEKQDYKQKLKALKI---------------------EVNKL 222
L+ L + A K+K+D ++L+ALK EV L
Sbjct: 1127 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVL 1186
Query: 223 KEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSEL 282
K+ L+E+T + Q +E ++Q+ + +EL +E+ KR L+ K E+ N++L
Sbjct: 1187 KKALDEETRSHEAQVQE---MRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADL 1243
Query: 283 HNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVD 342
++ + + +++ +E +Q SK + + + + + L+N V
Sbjct: 1244 AGELRVLGQAKQEVEHKKKKLEAQ---VQELQSKCSDGERARAELNDKVHKLQNEVESVT 1300
Query: 343 IKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFG--EKSVITLSSIFT 400
+ + K K A L Q + + E +K + T E+ +L
Sbjct: 1301 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1360
Query: 401 KDLVEKHNL 409
+++ K NL
Sbjct: 1361 EEMEAKQNL 1369
Score = 60.8 bits (146), Expect = 4e-09
Identities = 94/432 (21%), Positives = 184/432 (42%), Gaps = 71/432 (16%)
Query: 8 LAGRQNIGSE-------VEISTIEKQRKELQLLIG-----ELKDRDKELNDMVAVHQQQL 55
LA +NI S+ E EK+ K L L E K+ + N M+ + L
Sbjct: 1464 LAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1523
Query: 56 LSWEEDRQK-VLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQL 114
+S ++D K V LE+ LE ++ + + L +++A E ++ + +Q + Q
Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1583
Query: 115 QEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQA------REQALTTMIK---- 164
+ DL+AR+E +L Q+ + + +++AL K
Sbjct: 1584 ER-------------DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1630
Query: 165 --LKDKDII---------EAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLK 213
LKD ++ EA+ + + K + L DA+ + I ++ ++K K
Sbjct: 1631 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1690
Query: 214 ALKIEVNKLKEDL-------NEKTTENNEQREEIIRLKQEKSCLHDE----------LLF 256
+L+ ++ +L+EDL + E E EE+ ++ L DE L
Sbjct: 1691 SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEE 1750
Query: 257 TVEREKRKDELLN--IAKSKQ--ERTNSELHNLRQIYVKQQSDLQFL-NFNVENSQELIQ 311
+E E+ E ++ + K+ Q E+ ++EL R K +S Q L N E +L +
Sbjct: 1751 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1810
Query: 312 MYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSL-FKDQKFEAMLVQQNRSDK 370
M + + K+ ++ + ++ LE + +++ KSL KD+K + +L+Q ++
Sbjct: 1811 MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQV-EDER 1869
Query: 371 SSCDECKEKKQQ 382
++ KE+ ++
Sbjct: 1870 KMAEQYKEQAEK 1881
Score = 53.1 bits (126), Expect = 8e-07
Identities = 72/360 (20%), Positives = 147/360 (40%), Gaps = 43/360 (11%)
Query: 36 ELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKA 95
E++ ++ EL Q+ +E QK L E + L+ +L TE+
Sbjct: 860 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY--------- 910
Query: 96 LESNQMECQTALQKTQLQ--LQEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQ 153
E+ +M + A +K +L+ L EM + + L+A + ++ +++L Q+ + +
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 154 AREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLK 213
A Q L +E V K K LE + + KE++ ++++
Sbjct: 971 AARQKLQ----------LEKVT----AEAKIKKLEDEILVMDDQNNKLSKERKLLEERI- 1015
Query: 214 ALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKS 273
DL E E+ + + +LK + + EL +++E++ + L K
Sbjct: 1016 ----------SDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1065
Query: 274 KQERTNSELHNLRQIYVKQQSDL--QFLNFNVENSQELIQMYDSKMEESKALDSSRDM-- 329
K E S+ H Q ++L Q E L ++ D +++ AL R++
Sbjct: 1066 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1125
Query: 330 CLSDLE---NNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTV 386
+SDL+ ++ K EK ++ L ++ + ++ ++ E + K++Q TV
Sbjct: 1126 HISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTV 1185
Score = 50.8 bits (120), Expect = 4e-06
Identities = 80/391 (20%), Positives = 166/391 (42%), Gaps = 53/391 (13%)
Query: 22 TIEKQRKELQ---LLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLT-LEERCSKLEG 77
T+EK+ +L ++G+ K + + Q+L S D ++ L ++ KL+
Sbjct: 1235 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1294
Query: 78 ELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNET 137
E+ T ++ K L + + LQ TQ LQE ++ + S LE +
Sbjct: 1295 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1354
Query: 138 LSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMA 197
L + L E +++A+ Q L I + + ++ + D + + LE K
Sbjct: 1355 LQDQLDE------EMEAK-QNLERHISTLNIQLSDSKKKLQDFASTVEALEEG---KKRF 1404
Query: 198 ETCIVKEKQDYKQKLKA---LKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDEL 254
+ I Q Y++K A L+ N+L+++L++ + + QR+ + L ++K D+L
Sbjct: 1405 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNL-EKKQRKFDQL 1463
Query: 255 L---------FTVEREK-------RKDELLNIAKSKQE--RTNSELHNLRQIYVKQQSDL 296
L + ER++ ++ + L++A++ +E EL ++ + DL
Sbjct: 1464 LAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1523
Query: 297 ----QFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSL 352
+ NV ++ + +++MEE K L +LE D + L
Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQ-------LEELE------DELQATEDAKL 1570
Query: 353 FKDQKFEAMLVQQNRSDKSSCDECKEKKQQI 383
+ +A+ Q R ++ ++ +EK++Q+
Sbjct: 1571 RLEVNMQALKGQFERDLQARDEQNEEKRRQL 1601
Score = 45.4 bits (106), Expect = 2e-04
Identities = 78/441 (17%), Positives = 184/441 (41%), Gaps = 36/441 (8%)
Query: 18 VEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEG 77
+++S +K+ ++ + L++ K + QQ +EE LE+ ++L+
Sbjct: 1378 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ---YEEKAAAYDKLEKTKNRLQQ 1434
Query: 78 ELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNET 137
EL + + + V LE Q + L + + + A + + + + E + +
Sbjct: 1435 ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALS 1494
Query: 138 LSNTLVELSAQVGQLQAREQALTT--MIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAK 195
L+ L E L+A+E+ T M+K + +D++ + + + + + + AL
Sbjct: 1495 LARALEEA------LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1548
Query: 196 MAETCIVKEKQDYKQKLK--ALKIEVN------KLKEDLNEKTTENNEQREEIIR-LKQE 246
++E +D Q + L++EVN + + DL + +N E+R ++ R L +
Sbjct: 1549 EEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEY 1608
Query: 247 KSCLHDE----LLFTVEREKRKDELLNI---AKSKQERTNSELHNLRQIYVKQQSDLQFL 299
++ L DE L ++K + +L ++ A S + + LR++ + + + L
Sbjct: 1609 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1668
Query: 300 NFNVENSQELIQMYDSKMEESKALDSSRDMCLSDL---ENNHPKVDIKREKNQKSLFKDQ 356
+ E+ +++K+L++ DL E + D+++E+ + L
Sbjct: 1669 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1728
Query: 357 KFEAMLVQQNRSDKSSC----DECKEKKQQIDTVFG--EKSVITLSSIFTKDLVEKHNLP 410
L + R ++ +E +E++ ++ + K+ + + E+
Sbjct: 1729 SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQ 1788
Query: 411 WSLGGKTQIEPENKITLCKIH 431
+ + Q+E +NK K+H
Sbjct: 1789 KNESARQQLERQNKELRSKLH 1809
Score = 44.3 bits (103), Expect = 4e-04
Identities = 85/440 (19%), Positives = 179/440 (40%), Gaps = 71/440 (16%)
Query: 17 EVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLS----WEEDRQKVLTLEERC 72
E E+ ++++++ + + EL+ + +L + + Q+QL + + E + + L +
Sbjct: 865 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 924
Query: 73 SKLEGELHK----------RTEIIRSLTKKVKA----LESNQMECQTALQKTQLQ---LQ 115
+LE LH+ R + +++ KK+ LE E + A QK QL+ +
Sbjct: 925 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 984
Query: 116 EMAQKATHSSLLSED-----------LEARNETLSNTLVE------------------LS 146
+K L+ +D LE R L+ L E +S
Sbjct: 985 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1044
Query: 147 AQVGQLQAREQALTTMIKLKDK---DIIEAVNHIADCSGKFKML-------EHALRDAKM 196
+L+ E++ + KLK K D + IAD + L E L+ A
Sbjct: 1045 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1104
Query: 197 AETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLF 256
+ +K + +K++ L+ ++ L+EDL+ + N+ ++ L +E L EL
Sbjct: 1105 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1164
Query: 257 TVE--------REKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQE 308
T++ R KR+ E+ + K+ E T S ++++ K ++ L +E +
Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1224
Query: 309 LIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRS 368
D + + ++ L L +V+ K++K + + Q+ ++ R+
Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV---QELQSKCSDGERA 1281
Query: 369 DKSSCDECKEKKQQIDTVFG 388
D+ + + ++++V G
Sbjct: 1282 RAELNDKVHKLQNEVESVTG 1301
Score = 33.1 bits (74), Expect = 0.87
Identities = 37/194 (19%), Positives = 84/194 (43%), Gaps = 9/194 (4%)
Query: 209 KQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELL 268
+++++A + E+ K KE + E E ++ +L +EK+ L ++L E +E+
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 269 NIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRD 328
+K++ LH + +++ Q L + + + + ++EE +A
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK-- 975
Query: 329 MCLSDLENNHPKVDIKREKNQKSLFKDQ----KFEAMLVQQNRSDKSSCDECKEKKQQID 384
LE + IK+ +++ + DQ E L+++ SD ++ +E+K +
Sbjct: 976 ---LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032
Query: 385 TVFGEKSVITLSSI 398
T K +S +
Sbjct: 1033 TKLKNKHESMISEL 1046
Score = 29.6 bits (65), Expect = 9.7
Identities = 54/308 (17%), Positives = 118/308 (38%), Gaps = 42/308 (13%)
Query: 239 EIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLR-------QIYVK 291
++ R ++E DEL T ER+++ + L + K + E + L+ ++Y +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 292 QQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKS 351
+ L + +E++ ++++EE + D + + + +D++ + ++
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEE--DRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 352 LFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVI-TLSSIFTKDLVEKHNLP 410
+ QK + V K DE Q + + E+ ++ S T +L E+
Sbjct: 971 AAR-QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA 1029
Query: 411 WSLGGKTQIEPENKITLCKIHTKSPKCHGTGVQNEGKQPSETPTL-----SDEKQWHDVS 465
+L T+++ +++ + ++ + ++ E K E L D +H+
Sbjct: 1030 KNL---TKLKNKHESMISELEVR--------LKKEEKSRQELEKLKRKLEGDASDFHEQI 1078
Query: 466 VYLGLTNCPSSKHPEKLDVECQDQMERSEISCCQKNEACLGESGMCDSKCCHPSNFIIEA 525
L K + E Q + R + QKN A I E
Sbjct: 1079 ADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNAL---------------KKIREL 1123
Query: 526 PGHMSDVE 533
GH+SD++
Sbjct: 1124 EGHISDLQ 1131
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 73.6 bits (179), Expect = 6e-13
Identities = 96/429 (22%), Positives = 176/429 (41%), Gaps = 46/429 (10%)
Query: 11 RQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEE 70
+Q + E ++ E R++LQL + + K+L D + V Q ++R+ LEE
Sbjct: 957 QQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERK---LLEE 1013
Query: 71 RCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSED 130
R S L L + E ++LTK ES E + L+K + QE+ + L
Sbjct: 1014 RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEK-------LKRK 1066
Query: 131 LEARNETLSNTLVELSAQVG----QLQAREQALTTMIKLKDKDIIE---AVNHIADCSGK 183
LE + +L AQ+ QL +E+ L + D +I + A+ I + G
Sbjct: 1067 LEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH 1126
Query: 184 FKMLEHALRDAKMAETCIVKEKQDYKQKLKALKI---------------------EVNKL 222
L+ L + A K+K+D ++L+ALK EV L
Sbjct: 1127 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVL 1186
Query: 223 KEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSEL 282
K+ L+E+T + Q +E ++Q+ + +EL +E+ KR L+ K E+ N++L
Sbjct: 1187 KKALDEETRSHEAQVQE---MRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADL 1243
Query: 283 HNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVD 342
++ + + +++ +E +Q SK + + + + + L+N V
Sbjct: 1244 AGELRVLGQAKQEVEHKKKKLEAQ---VQELQSKCSDGERARAELNDKVHKLQNEVESVT 1300
Query: 343 IKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFG--EKSVITLSSIFT 400
+ + K K A L Q + + E +K + T E+ +L
Sbjct: 1301 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1360
Query: 401 KDLVEKHNL 409
+++ K NL
Sbjct: 1361 EEMEAKQNL 1369
Score = 60.8 bits (146), Expect = 4e-09
Identities = 94/432 (21%), Positives = 184/432 (42%), Gaps = 71/432 (16%)
Query: 8 LAGRQNIGSE-------VEISTIEKQRKELQLLIG-----ELKDRDKELNDMVAVHQQQL 55
LA +NI S+ E EK+ K L L E K+ + N M+ + L
Sbjct: 1464 LAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1523
Query: 56 LSWEEDRQK-VLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQL 114
+S ++D K V LE+ LE ++ + + L +++A E ++ + +Q + Q
Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1583
Query: 115 QEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQA------REQALTTMIK---- 164
+ DL+AR+E +L Q+ + + +++AL K
Sbjct: 1584 ER-------------DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1630
Query: 165 --LKDKDII---------EAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLK 213
LKD ++ EA+ + + K + L DA+ + I ++ ++K K
Sbjct: 1631 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1690
Query: 214 ALKIEVNKLKEDL-------NEKTTENNEQREEIIRLKQEKSCLHDE----------LLF 256
+L+ ++ +L+EDL + E E EE+ ++ L DE L
Sbjct: 1691 SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEE 1750
Query: 257 TVEREKRKDELLN--IAKSKQ--ERTNSELHNLRQIYVKQQSDLQFL-NFNVENSQELIQ 311
+E E+ E ++ + K+ Q E+ ++EL R K +S Q L N E +L +
Sbjct: 1751 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1810
Query: 312 MYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSL-FKDQKFEAMLVQQNRSDK 370
M + + K+ ++ + ++ LE + +++ KSL KD+K + +L+Q ++
Sbjct: 1811 MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQV-EDER 1869
Query: 371 SSCDECKEKKQQ 382
++ KE+ ++
Sbjct: 1870 KMAEQYKEQAEK 1881
Score = 53.1 bits (126), Expect = 8e-07
Identities = 72/360 (20%), Positives = 147/360 (40%), Gaps = 43/360 (11%)
Query: 36 ELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKA 95
E++ ++ EL Q+ +E QK L E + L+ +L TE+
Sbjct: 860 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY--------- 910
Query: 96 LESNQMECQTALQKTQLQ--LQEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQ 153
E+ +M + A +K +L+ L EM + + L+A + ++ +++L Q+ + +
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 154 AREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLK 213
A Q L +E V K K LE + + KE++ ++++
Sbjct: 971 AARQKLQ----------LEKVT----AEAKIKKLEDEILVMDDQNNKLSKERKLLEERI- 1015
Query: 214 ALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKS 273
DL E E+ + + +LK + + EL +++E++ + L K
Sbjct: 1016 ----------SDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1065
Query: 274 KQERTNSELHNLRQIYVKQQSDL--QFLNFNVENSQELIQMYDSKMEESKALDSSRDM-- 329
K E S+ H Q ++L Q E L ++ D +++ AL R++
Sbjct: 1066 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1125
Query: 330 CLSDLE---NNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTV 386
+SDL+ ++ K EK ++ L ++ + ++ ++ E + K++Q TV
Sbjct: 1126 HISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTV 1185
Score = 50.8 bits (120), Expect = 4e-06
Identities = 80/391 (20%), Positives = 166/391 (42%), Gaps = 53/391 (13%)
Query: 22 TIEKQRKELQ---LLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLT-LEERCSKLEG 77
T+EK+ +L ++G+ K + + Q+L S D ++ L ++ KL+
Sbjct: 1235 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1294
Query: 78 ELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNET 137
E+ T ++ K L + + LQ TQ LQE ++ + S LE +
Sbjct: 1295 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1354
Query: 138 LSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMA 197
L + L E +++A+ Q L I + + ++ + D + + LE K
Sbjct: 1355 LQDQLDE------EMEAK-QNLERHISTLNIQLSDSKKKLQDFASTVEALEEG---KKRF 1404
Query: 198 ETCIVKEKQDYKQKLKA---LKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDEL 254
+ I Q Y++K A L+ N+L+++L++ + + QR+ + L ++K D+L
Sbjct: 1405 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNL-EKKQRKFDQL 1463
Query: 255 L---------FTVEREK-------RKDELLNIAKSKQE--RTNSELHNLRQIYVKQQSDL 296
L + ER++ ++ + L++A++ +E EL ++ + DL
Sbjct: 1464 LAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1523
Query: 297 ----QFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSL 352
+ NV ++ + +++MEE K L +LE D + L
Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQ-------LEELE------DELQATEDAKL 1570
Query: 353 FKDQKFEAMLVQQNRSDKSSCDECKEKKQQI 383
+ +A+ Q R ++ ++ +EK++Q+
Sbjct: 1571 RLEVNMQALKGQFERDLQARDEQNEEKRRQL 1601
Score = 45.4 bits (106), Expect = 2e-04
Identities = 78/441 (17%), Positives = 184/441 (41%), Gaps = 36/441 (8%)
Query: 18 VEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEG 77
+++S +K+ ++ + L++ K + QQ +EE LE+ ++L+
Sbjct: 1378 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ---YEEKAAAYDKLEKTKNRLQQ 1434
Query: 78 ELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNET 137
EL + + + V LE Q + L + + + A + + + + E + +
Sbjct: 1435 ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALS 1494
Query: 138 LSNTLVELSAQVGQLQAREQALTT--MIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAK 195
L+ L E L+A+E+ T M+K + +D++ + + + + + + AL
Sbjct: 1495 LARALEEA------LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1548
Query: 196 MAETCIVKEKQDYKQKLK--ALKIEVN------KLKEDLNEKTTENNEQREEIIR-LKQE 246
++E +D Q + L++EVN + + DL + +N E+R ++ R L +
Sbjct: 1549 EEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEY 1608
Query: 247 KSCLHDE----LLFTVEREKRKDELLNI---AKSKQERTNSELHNLRQIYVKQQSDLQFL 299
++ L DE L ++K + +L ++ A S + + LR++ + + + L
Sbjct: 1609 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1668
Query: 300 NFNVENSQELIQMYDSKMEESKALDSSRDMCLSDL---ENNHPKVDIKREKNQKSLFKDQ 356
+ E+ +++K+L++ DL E + D+++E+ + L
Sbjct: 1669 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1728
Query: 357 KFEAMLVQQNRSDKSSC----DECKEKKQQIDTVFG--EKSVITLSSIFTKDLVEKHNLP 410
L + R ++ +E +E++ ++ + K+ + + E+
Sbjct: 1729 SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQ 1788
Query: 411 WSLGGKTQIEPENKITLCKIH 431
+ + Q+E +NK K+H
Sbjct: 1789 KNESARQQLERQNKELRSKLH 1809
Score = 44.3 bits (103), Expect = 4e-04
Identities = 85/440 (19%), Positives = 179/440 (40%), Gaps = 71/440 (16%)
Query: 17 EVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLS----WEEDRQKVLTLEERC 72
E E+ ++++++ + + EL+ + +L + + Q+QL + + E + + L +
Sbjct: 865 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 924
Query: 73 SKLEGELHK----------RTEIIRSLTKKVKA----LESNQMECQTALQKTQLQ---LQ 115
+LE LH+ R + +++ KK+ LE E + A QK QL+ +
Sbjct: 925 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 984
Query: 116 EMAQKATHSSLLSED-----------LEARNETLSNTLVE------------------LS 146
+K L+ +D LE R L+ L E +S
Sbjct: 985 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1044
Query: 147 AQVGQLQAREQALTTMIKLKDK---DIIEAVNHIADCSGKFKML-------EHALRDAKM 196
+L+ E++ + KLK K D + IAD + L E L+ A
Sbjct: 1045 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1104
Query: 197 AETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLF 256
+ +K + +K++ L+ ++ L+EDL+ + N+ ++ L +E L EL
Sbjct: 1105 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1164
Query: 257 TVE--------REKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQE 308
T++ R KR+ E+ + K+ E T S ++++ K ++ L +E +
Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1224
Query: 309 LIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRS 368
D + + ++ L L +V+ K++K + + Q+ ++ R+
Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV---QELQSKCSDGERA 1281
Query: 369 DKSSCDECKEKKQQIDTVFG 388
D+ + + ++++V G
Sbjct: 1282 RAELNDKVHKLQNEVESVTG 1301
Score = 33.1 bits (74), Expect = 0.87
Identities = 37/194 (19%), Positives = 84/194 (43%), Gaps = 9/194 (4%)
Query: 209 KQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELL 268
+++++A + E+ K KE + E E ++ +L +EK+ L ++L E +E+
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 269 NIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRD 328
+K++ LH + +++ Q L + + + + ++EE +A
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK-- 975
Query: 329 MCLSDLENNHPKVDIKREKNQKSLFKDQ----KFEAMLVQQNRSDKSSCDECKEKKQQID 384
LE + IK+ +++ + DQ E L+++ SD ++ +E+K +
Sbjct: 976 ---LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032
Query: 385 TVFGEKSVITLSSI 398
T K +S +
Sbjct: 1033 TKLKNKHESMISEL 1046
Score = 29.6 bits (65), Expect = 9.7
Identities = 54/308 (17%), Positives = 118/308 (38%), Gaps = 42/308 (13%)
Query: 239 EIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLR-------QIYVK 291
++ R ++E DEL T ER+++ + L + K + E + L+ ++Y +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 292 QQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKS 351
+ L + +E++ ++++EE + D + + + +D++ + ++
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEE--DRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 352 LFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVI-TLSSIFTKDLVEKHNLP 410
+ QK + V K DE Q + + E+ ++ S T +L E+
Sbjct: 971 AAR-QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA 1029
Query: 411 WSLGGKTQIEPENKITLCKIHTKSPKCHGTGVQNEGKQPSETPTL-----SDEKQWHDVS 465
+L T+++ +++ + ++ + ++ E K E L D +H+
Sbjct: 1030 KNL---TKLKNKHESMISELEVR--------LKKEEKSRQELEKLKRKLEGDASDFHEQI 1078
Query: 466 VYLGLTNCPSSKHPEKLDVECQDQMERSEISCCQKNEACLGESGMCDSKCCHPSNFIIEA 525
L K + E Q + R + QKN A I E
Sbjct: 1079 ADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNAL---------------KKIREL 1123
Query: 526 PGHMSDVE 533
GH+SD++
Sbjct: 1124 EGHISDLQ 1131
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 73.6 bits (179), Expect = 6e-13
Identities = 96/429 (22%), Positives = 176/429 (41%), Gaps = 46/429 (10%)
Query: 11 RQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEE 70
+Q + E ++ E R++LQL + + K+L D + V Q ++R+ LEE
Sbjct: 950 QQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERK---LLEE 1006
Query: 71 RCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSED 130
R S L L + E ++LTK ES E + L+K + QE+ + L
Sbjct: 1007 RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEK-------LKRK 1059
Query: 131 LEARNETLSNTLVELSAQVG----QLQAREQALTTMIKLKDKDIIE---AVNHIADCSGK 183
LE + +L AQ+ QL +E+ L + D +I + A+ I + G
Sbjct: 1060 LEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH 1119
Query: 184 FKMLEHALRDAKMAETCIVKEKQDYKQKLKALKI---------------------EVNKL 222
L+ L + A K+K+D ++L+ALK EV L
Sbjct: 1120 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVL 1179
Query: 223 KEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSEL 282
K+ L+E+T + Q +E ++Q+ + +EL +E+ KR L+ K E+ N++L
Sbjct: 1180 KKALDEETRSHEAQVQE---MRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADL 1236
Query: 283 HNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVD 342
++ + + +++ +E +Q SK + + + + + L+N V
Sbjct: 1237 AGELRVLGQAKQEVEHKKKKLEAQ---VQELQSKCSDGERARAELNDKVHKLQNEVESVT 1293
Query: 343 IKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFG--EKSVITLSSIFT 400
+ + K K A L Q + + E +K + T E+ +L
Sbjct: 1294 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1353
Query: 401 KDLVEKHNL 409
+++ K NL
Sbjct: 1354 EEMEAKQNL 1362
Score = 60.8 bits (146), Expect = 4e-09
Identities = 94/432 (21%), Positives = 184/432 (42%), Gaps = 71/432 (16%)
Query: 8 LAGRQNIGSE-------VEISTIEKQRKELQLLIG-----ELKDRDKELNDMVAVHQQQL 55
LA +NI S+ E EK+ K L L E K+ + N M+ + L
Sbjct: 1457 LAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1516
Query: 56 LSWEEDRQK-VLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQL 114
+S ++D K V LE+ LE ++ + + L +++A E ++ + +Q + Q
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1576
Query: 115 QEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQA------REQALTTMIK---- 164
+ DL+AR+E +L Q+ + + +++AL K
Sbjct: 1577 ER-------------DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1623
Query: 165 --LKDKDII---------EAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLK 213
LKD ++ EA+ + + K + L DA+ + I ++ ++K K
Sbjct: 1624 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1683
Query: 214 ALKIEVNKLKEDL-------NEKTTENNEQREEIIRLKQEKSCLHDE----------LLF 256
+L+ ++ +L+EDL + E E EE+ ++ L DE L
Sbjct: 1684 SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEE 1743
Query: 257 TVEREKRKDELLN--IAKSKQ--ERTNSELHNLRQIYVKQQSDLQFL-NFNVENSQELIQ 311
+E E+ E ++ + K+ Q E+ ++EL R K +S Q L N E +L +
Sbjct: 1744 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1803
Query: 312 MYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSL-FKDQKFEAMLVQQNRSDK 370
M + + K+ ++ + ++ LE + +++ KSL KD+K + +L+Q ++
Sbjct: 1804 MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQV-EDER 1862
Query: 371 SSCDECKEKKQQ 382
++ KE+ ++
Sbjct: 1863 KMAEQYKEQAEK 1874
Score = 53.1 bits (126), Expect = 8e-07
Identities = 72/360 (20%), Positives = 147/360 (40%), Gaps = 43/360 (11%)
Query: 36 ELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKA 95
E++ ++ EL Q+ +E QK L E + L+ +L TE+
Sbjct: 853 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY--------- 903
Query: 96 LESNQMECQTALQKTQLQ--LQEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQ 153
E+ +M + A +K +L+ L EM + + L+A + ++ +++L Q+ + +
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 154 AREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLK 213
A Q L +E V K K LE + + KE++ ++++
Sbjct: 964 AARQKLQ----------LEKVT----AEAKIKKLEDEILVMDDQNNKLSKERKLLEERI- 1008
Query: 214 ALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKS 273
DL E E+ + + +LK + + EL +++E++ + L K
Sbjct: 1009 ----------SDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1058
Query: 274 KQERTNSELHNLRQIYVKQQSDL--QFLNFNVENSQELIQMYDSKMEESKALDSSRDM-- 329
K E S+ H Q ++L Q E L ++ D +++ AL R++
Sbjct: 1059 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1118
Query: 330 CLSDLE---NNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTV 386
+SDL+ ++ K EK ++ L ++ + ++ ++ E + K++Q TV
Sbjct: 1119 HISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTV 1178
Score = 50.8 bits (120), Expect = 4e-06
Identities = 80/391 (20%), Positives = 166/391 (42%), Gaps = 53/391 (13%)
Query: 22 TIEKQRKELQ---LLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLT-LEERCSKLEG 77
T+EK+ +L ++G+ K + + Q+L S D ++ L ++ KL+
Sbjct: 1228 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
Query: 78 ELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNET 137
E+ T ++ K L + + LQ TQ LQE ++ + S LE +
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
Query: 138 LSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMA 197
L + L E +++A+ Q L I + + ++ + D + + LE K
Sbjct: 1348 LQDQLDE------EMEAK-QNLERHISTLNIQLSDSKKKLQDFASTVEALEEG---KKRF 1397
Query: 198 ETCIVKEKQDYKQKLKA---LKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDEL 254
+ I Q Y++K A L+ N+L+++L++ + + QR+ + L ++K D+L
Sbjct: 1398 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNL-EKKQRKFDQL 1456
Query: 255 L---------FTVEREK-------RKDELLNIAKSKQE--RTNSELHNLRQIYVKQQSDL 296
L + ER++ ++ + L++A++ +E EL ++ + DL
Sbjct: 1457 LAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1516
Query: 297 ----QFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSL 352
+ NV ++ + +++MEE K L +LE D + L
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQ-------LEELE------DELQATEDAKL 1563
Query: 353 FKDQKFEAMLVQQNRSDKSSCDECKEKKQQI 383
+ +A+ Q R ++ ++ +EK++Q+
Sbjct: 1564 RLEVNMQALKGQFERDLQARDEQNEEKRRQL 1594
Score = 45.4 bits (106), Expect = 2e-04
Identities = 78/441 (17%), Positives = 184/441 (41%), Gaps = 36/441 (8%)
Query: 18 VEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEG 77
+++S +K+ ++ + L++ K + QQ +EE LE+ ++L+
Sbjct: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ---YEEKAAAYDKLEKTKNRLQQ 1427
Query: 78 ELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNET 137
EL + + + V LE Q + L + + + A + + + + E + +
Sbjct: 1428 ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALS 1487
Query: 138 LSNTLVELSAQVGQLQAREQALTT--MIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAK 195
L+ L E L+A+E+ T M+K + +D++ + + + + + + AL
Sbjct: 1488 LARALEEA------LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1541
Query: 196 MAETCIVKEKQDYKQKLK--ALKIEVN------KLKEDLNEKTTENNEQREEIIR-LKQE 246
++E +D Q + L++EVN + + DL + +N E+R ++ R L +
Sbjct: 1542 EEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEY 1601
Query: 247 KSCLHDE----LLFTVEREKRKDELLNI---AKSKQERTNSELHNLRQIYVKQQSDLQFL 299
++ L DE L ++K + +L ++ A S + + LR++ + + + L
Sbjct: 1602 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1661
Query: 300 NFNVENSQELIQMYDSKMEESKALDSSRDMCLSDL---ENNHPKVDIKREKNQKSLFKDQ 356
+ E+ +++K+L++ DL E + D+++E+ + L
Sbjct: 1662 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1721
Query: 357 KFEAMLVQQNRSDKSSC----DECKEKKQQIDTVFG--EKSVITLSSIFTKDLVEKHNLP 410
L + R ++ +E +E++ ++ + K+ + + E+
Sbjct: 1722 SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQ 1781
Query: 411 WSLGGKTQIEPENKITLCKIH 431
+ + Q+E +NK K+H
Sbjct: 1782 KNESARQQLERQNKELRSKLH 1802
Score = 44.3 bits (103), Expect = 4e-04
Identities = 85/440 (19%), Positives = 179/440 (40%), Gaps = 71/440 (16%)
Query: 17 EVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLS----WEEDRQKVLTLEERC 72
E E+ ++++++ + + EL+ + +L + + Q+QL + + E + + L +
Sbjct: 858 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 917
Query: 73 SKLEGELHK----------RTEIIRSLTKKVKA----LESNQMECQTALQKTQLQ---LQ 115
+LE LH+ R + +++ KK+ LE E + A QK QL+ +
Sbjct: 918 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 977
Query: 116 EMAQKATHSSLLSED-----------LEARNETLSNTLVE------------------LS 146
+K L+ +D LE R L+ L E +S
Sbjct: 978 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1037
Query: 147 AQVGQLQAREQALTTMIKLKDK---DIIEAVNHIADCSGKFKML-------EHALRDAKM 196
+L+ E++ + KLK K D + IAD + L E L+ A
Sbjct: 1038 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1097
Query: 197 AETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLF 256
+ +K + +K++ L+ ++ L+EDL+ + N+ ++ L +E L EL
Sbjct: 1098 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1157
Query: 257 TVE--------REKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQE 308
T++ R KR+ E+ + K+ E T S ++++ K ++ L +E +
Sbjct: 1158 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1217
Query: 309 LIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRS 368
D + + ++ L L +V+ K++K + + Q+ ++ R+
Sbjct: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV---QELQSKCSDGERA 1274
Query: 369 DKSSCDECKEKKQQIDTVFG 388
D+ + + ++++V G
Sbjct: 1275 RAELNDKVHKLQNEVESVTG 1294
Score = 33.1 bits (74), Expect = 0.87
Identities = 37/194 (19%), Positives = 84/194 (43%), Gaps = 9/194 (4%)
Query: 209 KQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELL 268
+++++A + E+ K KE + E E ++ +L +EK+ L ++L E +E+
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 269 NIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRD 328
+K++ LH + +++ Q L + + + + ++EE +A
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK-- 968
Query: 329 MCLSDLENNHPKVDIKREKNQKSLFKDQ----KFEAMLVQQNRSDKSSCDECKEKKQQID 384
LE + IK+ +++ + DQ E L+++ SD ++ +E+K +
Sbjct: 969 ---LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025
Query: 385 TVFGEKSVITLSSI 398
T K +S +
Sbjct: 1026 TKLKNKHESMISEL 1039
Score = 29.6 bits (65), Expect = 9.7
Identities = 54/308 (17%), Positives = 118/308 (38%), Gaps = 42/308 (13%)
Query: 239 EIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLR-------QIYVK 291
++ R ++E DEL T ER+++ + L + K + E + L+ ++Y +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 292 QQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKS 351
+ L + +E++ ++++EE + D + + + +D++ + ++
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEE--DRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 352 LFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVI-TLSSIFTKDLVEKHNLP 410
+ QK + V K DE Q + + E+ ++ S T +L E+
Sbjct: 964 AAR-QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA 1022
Query: 411 WSLGGKTQIEPENKITLCKIHTKSPKCHGTGVQNEGKQPSETPTL-----SDEKQWHDVS 465
+L T+++ +++ + ++ + ++ E K E L D +H+
Sbjct: 1023 KNL---TKLKNKHESMISELEVR--------LKKEEKSRQELEKLKRKLEGDASDFHEQI 1071
Query: 466 VYLGLTNCPSSKHPEKLDVECQDQMERSEISCCQKNEACLGESGMCDSKCCHPSNFIIEA 525
L K + E Q + R + QKN A I E
Sbjct: 1072 ADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNAL---------------KKIREL 1116
Query: 526 PGHMSDVE 533
GH+SD++
Sbjct: 1117 EGHISDLQ 1124
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 73.2 bits (178), Expect = 8e-13
Identities = 96/449 (21%), Positives = 201/449 (44%), Gaps = 48/449 (10%)
Query: 1 MNPPAAFLAGRQNIGSEVEIS--TIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSW 58
++ AA A R ++ + ++ + ++ +++EL + +L +L D Q
Sbjct: 652 LSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHL 711
Query: 59 EEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMA 118
+E ++K L+LE++ +LEG+ +K LE++ +E + + ++ LQ+
Sbjct: 712 KEYKEKYLSLEQKTEELEGQ--------------IKKLEADSLEVKASKEQALQDLQQQR 757
Query: 119 QKATHSSL----LSEDLEARNETLSNTLVELSAQVGQLQAREQALT-----TMIKLKDKD 169
Q T L LS+ LE E +S+T ++L + L++ +Q LT I +D +
Sbjct: 758 QLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFE 817
Query: 170 IIEAVNHI--ADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLN 227
+ I + + + + L+ KM + ++ E K KL + + LK +
Sbjct: 818 TLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVS---DSLKNSKS 874
Query: 228 EKTTENNEQREEIIRL----KQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELH 283
E EN + + I+ L K+ K L ++ T++ +K + L K + EL+
Sbjct: 875 EFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELN 934
Query: 284 NLRQIYVKQQSDLQFLNFNVE-----NSQELIQMYDSKMEESKALDSSRDMCLSDLENNH 338
++++ ++ Q+ L+ N E N EL Q + K ++ +AL ++ ++ L+
Sbjct: 935 SMQEQLIQAQNTLK-QNEKEEQQLQGNINELKQSSEQKKKQIEALQG--ELKIAVLQKTE 991
Query: 339 PKVDIKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSI 398
+ ++++ Q + + E + V QN +KS + KQ +G +S + +
Sbjct: 992 LENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQ----ETFKQLQSDFYGRESELLATRQ 1047
Query: 399 FTKDLVEKHNLPWS--LGGKTQIEPENKI 425
K + EK +L + + QI +NK+
Sbjct: 1048 DLKSVEEKLSLAQEDLISNRNQIGNQNKL 1076
Score = 64.7 bits (156), Expect = 3e-10
Identities = 91/446 (20%), Positives = 196/446 (43%), Gaps = 65/446 (14%)
Query: 23 IEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLE------ 76
+ ++ + Q L EL + + + + A +Q EE Q L L+ ++L
Sbjct: 367 LSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLET 426
Query: 77 ----GELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLE 132
GE H R + R L+ + K ++ Q L+ ++L+ +++ +K T+S+ L L+
Sbjct: 427 ERQLGEAHGRLKEQRQLSSE-KLMDKEQQVADLQLKLSRLE-EQLKEKVTNSTELQHQLD 484
Query: 133 ARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALR 192
+ Q + QA +Q+ T ++ D+ + + I D K + LE L+
Sbjct: 485 KTKQ-----------QHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQ 533
Query: 193 DAKMAETCIVKEKQDYKQKLKALKIE---VNKLKE---DLNEKTTENNEQ-REEIIRLKQ 245
+K + + KE++D K++A + E +N+L+E L E+ T+ E+ + + KQ
Sbjct: 534 KSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQ 593
Query: 246 EKSCLHDELLFTVEREK-----RKDELLNIAKSKQERTNSELHNLRQ------IYVKQQS 294
+ LHD+ V+ +K +D +L++ S E NS+L+ ++ I +K ++
Sbjct: 594 AQENLHDQ----VQEQKAHLRAAQDRVLSLETSVNE-LNSQLNESKEKVSQLDIQIKAKT 648
Query: 295 DLQF------------LNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKV- 341
+L L +++ +Q +Q K +E + + D + L++
Sbjct: 649 ELLLSAEAAKTAQRADLQNHLDTAQNALQ---DKQQELNKITTQLDQVTAKLQDKQEHCS 705
Query: 342 ---DIKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSI 398
+E +K L +QK E + Q + + S + K+Q + + ++ + T +
Sbjct: 706 QLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLEL 765
Query: 399 FTKDLVEKHNLPWSLGGKTQIEPENK 424
+L ++ + + T+++ + K
Sbjct: 766 RATELSKQLEMEKEIVSSTRLDLQKK 791
Score = 61.2 bits (147), Expect = 3e-09
Identities = 76/329 (23%), Positives = 149/329 (45%), Gaps = 61/329 (18%)
Query: 17 EVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLE 76
+V++ K++KEL+ + + K+ +L + Q+QL+ + ++ E+ +L+
Sbjct: 902 QVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQN---EKEEQQLQ 958
Query: 77 GELHKRTEIIRSLTKKVKALESNQMECQTA-LQKTQLQ----------LQEMAQKATHSS 125
G ++ E+ +S +K K +E+ Q E + A LQKT+L+ QE+A + S
Sbjct: 959 GNIN---ELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKIS 1015
Query: 126 LLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTM---IKLKDKDIIEAVNHIADCSG 182
+L + E ET + + +L A Q L ++ + L +D+I N I + +
Sbjct: 1016 VLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNK 1075
Query: 183 KFKML---------EHALRDAKMAETC----------IVKEKQDYKQKLKALKIEVNKLK 223
+ L + A ++ ++ E C +KEK+ +K K +IE K +
Sbjct: 1076 LIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCR 1135
Query: 224 ED-----LNEKTTENN-EQREEIIRLKQEKSCL----------HDELLFTVEREKRKDEL 267
++ LNE+ + E +EI LK K L D L VE+EKR ++
Sbjct: 1136 QEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQI 1195
Query: 268 LNIAKSKQERTNSELHNLRQIYVKQQSDL 296
L +++ E L++ ++++++ L
Sbjct: 1196 L------KDQVKKEEEELKKEFIEKEAKL 1218
Score = 52.0 bits (123), Expect = 2e-06
Identities = 83/453 (18%), Positives = 179/453 (39%), Gaps = 92/453 (20%)
Query: 6 AFLAGRQNIGSEVEISTIEKQRKELQL------LIGELKDRDKELNDMVAVHQQQLLSWE 59
A L +Q S++E E + K L L L G++K + + ++ A +Q L +
Sbjct: 695 AKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQ 754
Query: 60 EDRQKVLTLEERCSKLEGELHKRTEIIRS----LTKKVKALESNQMECQTALQKTQLQLQ 115
+ RQ LE R ++L +L EI+ S L KK +ALES + + ++ Q+ Q
Sbjct: 755 QQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQ 814
Query: 116 EMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVN 175
+ LS++ + ++E L+N + ++ +++ ++AL T + + + +
Sbjct: 815 DF-------ETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSD 867
Query: 176 HIADCSGKFK--------------------------MLEHALRDAKMAETCIVKEK---- 205
+ + +F+ +E+ L++ K + + KEK
Sbjct: 868 SLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASH 927
Query: 206 --------------------------------------QDYKQKLKALKIEVNKLKEDLN 227
Q +QK K ++ +LK +
Sbjct: 928 QLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVL 987
Query: 228 EKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQ 287
+KT N+ ++++ + QE + +++ ++ E +S SEL RQ
Sbjct: 988 QKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQ 1047
Query: 288 IYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREK 347
+ L ++ +++ I + ++E K ++ LE + K + + ++
Sbjct: 1048 DLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKAT-------LEQDSAKKEQQLQE 1100
Query: 348 NQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKK 380
K+L QK +++ ++ ++KS E +E K
Sbjct: 1101 RCKALQDIQKEKSLKEKELVNEKSKLAEIEEIK 1133
Score = 42.0 bits (97), Expect = 0.002
Identities = 79/342 (23%), Positives = 141/342 (41%), Gaps = 77/342 (22%)
Query: 24 EKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGELHKRT 83
E+++K+++ L GELK + ++ QQQL + Q++ +E+ S L+ K
Sbjct: 969 EQKKKQIEALQGELKIAVLQKTELENKLQQQLT---QAAQELAAEKEKISVLQNNYEKSQ 1025
Query: 84 EIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNETLSN--- 140
E + L ES + + L+ + +L SL EDL + + N
Sbjct: 1026 ETFKQLQSDFYGRESELLATRQDLKSVEEKL----------SLAQEDLISNRNQIGNQNK 1075
Query: 141 ----------TLVELSAQVGQ-LQAREQALTTMIK---LKDKDIIEAVNHIADCSG---- 182
TL + SA+ Q LQ R +AL + K LK+K+++ + +A+
Sbjct: 1076 LIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCR 1135
Query: 183 ---KFKMLEHALRDAKM-----------AETCIVKEKQDYKQK---LKA----------- 214
+ L L+ K+ A+ ++++K + + K LKA
Sbjct: 1136 QEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQI 1195
Query: 215 LKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHD--ELLFTVEREKRKDELLNIAK 272
LK +V K +E+L ++ E + I+ K+ H+ E T++ + L + K
Sbjct: 1196 LKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKK 1255
Query: 273 SKQ--ERTNSELHNLRQIYVKQQSDLQ----FLNFNVENSQE 308
Q +R SEL KQ DL+ L V+N+Q+
Sbjct: 1256 EWQSSQRRVSELE-------KQTDDLRGEIAVLEATVQNNQD 1290
Score = 40.4 bits (93), Expect = 0.005
Identities = 71/379 (18%), Positives = 146/379 (38%), Gaps = 67/379 (17%)
Query: 16 SEVEISTIEKQRKELQ---LLIGELKDRDKELNDMVAVHQQQLLS-WEEDRQKVLTLEER 71
S E+ ++E+Q +E Q I ++KD ++ +A + S ++E+R E++
Sbjct: 133 SSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQK 192
Query: 72 CSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDL 131
++L EL+K +I+ L K + L+ +E L+K +Q+Q + T +
Sbjct: 193 VTRLTEELNKEATVIQDL--KTELLQRPGIEDVAVLKKELVQVQTLMDNMTL------ER 244
Query: 132 EARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHAL 191
E +E L + +L +Q +A L + + +++ V
Sbjct: 245 ERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQ---------------- 288
Query: 192 RDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLH 251
E+ KLK +NE T +N E +++ +Q+ + L
Sbjct: 289 --------------------------ELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLE 322
Query: 252 DELLFTVEREKRKDELLN----IAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQ 307
++ +K L+ + Q R ++ +L +I+V+ + E
Sbjct: 323 EKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELS 382
Query: 308 ELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQ---KSLFKDQKFEAMLVQ 364
E+ Y E K L R+ E + ++ E NQ K L +++ +
Sbjct: 383 EVETKYQHLKAEFKQLQQQRE------EKEQHGLQLQSEINQLHSKLLETERQLGEAHGR 436
Query: 365 QNRSDKSSCDECKEKKQQI 383
+ S ++ +K+QQ+
Sbjct: 437 LKEQRQLSSEKLMDKEQQV 455
Score = 38.1 bits (87), Expect = 0.027
Identities = 29/116 (25%), Positives = 58/116 (50%), Gaps = 19/116 (16%)
Query: 20 ISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGEL 79
+ T++K+ + Q + EL+ + +L +AV + + + +++R+ +L ERC K EGE+
Sbjct: 1250 LGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALL---ERCLKGEGEI 1306
Query: 80 HKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARN 135
K L++ +E Q L T +QE+ ++ + SL + +A N
Sbjct: 1307 EK--------------LQTKVLELQRKLDNTTAAVQELGRE--NQSLQIKHTQALN 1346
Score = 33.5 bits (75), Expect = 0.67
Identities = 16/81 (19%), Positives = 44/81 (54%)
Query: 58 WEEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEM 117
W+ +++V LE++ L GE+ +++ + +AL ++ + ++K Q ++ E+
Sbjct: 1257 WQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLEL 1316
Query: 118 AQKATHSSLLSEDLEARNETL 138
+K +++ ++L N++L
Sbjct: 1317 QRKLDNTTAAVQELGRENQSL 1337
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 72.8 bits (177), Expect = 1e-12
Identities = 83/397 (20%), Positives = 173/397 (43%), Gaps = 47/397 (11%)
Query: 11 RQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQL--LSWEEDRQKVLT- 67
++ +E ++ + ++ L I +L K L + HQQ L L EED+ LT
Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQE---AHQQTLDDLQAEEDKVNTLTK 1028
Query: 68 ----LEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATH 123
LE++ LEG L + ++ L + + LE + Q ++ + + Q++ +K
Sbjct: 1029 AKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKK 1088
Query: 124 SSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGK 183
+L+++ E ++L ++ +LQAR + L I+ + +A +D S +
Sbjct: 1089 KEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRE 1148
Query: 184 FKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRL 243
+ + L +A A + ++ K + E K++ DL E T + +E +R
Sbjct: 1149 LEEISERLEEAGGATSAQIEMN-------KKREAEFQKMRRDLEEATLQ-HEATAATLRK 1200
Query: 244 KQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNV 303
K S E ++ D L + K K E+ SE+ + ++ L NV
Sbjct: 1201 KHADS--------VAELGEQIDNLQRV-KQKLEKEKSEM----------KMEIDDLASNV 1241
Query: 304 E-------NSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQ 356
E N +++ + + ++ E K+ + + ++DL + ++ E + S D+
Sbjct: 1242 ETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGR--LQTESGEFSRQLDE 1299
Query: 357 KFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVI 393
K EA++ Q +R ++ + +E K+Q++ K+ +
Sbjct: 1300 K-EALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNAL 1335
Score = 58.2 bits (139), Expect = 3e-08
Identities = 74/368 (20%), Positives = 156/368 (42%), Gaps = 32/368 (8%)
Query: 55 LLSWEEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKAL--ESNQMECQT------- 105
LL E +++ T++E K++ EL K + L +K+ L E N ++ Q
Sbjct: 845 LLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGL 904
Query: 106 --------ALQKTQLQLQ----EMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQ 153
L KT++QL+ E+ ++A ++ +L A+ L + EL + L+
Sbjct: 905 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 964
Query: 154 ---AREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQ 210
A+ + + K K++ E + + + K + AL++A ++ ++D
Sbjct: 965 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1024
Query: 211 KLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKS---CLHDELLFTVEREKRK-DE 266
L KI++ + +DL + + R ++ R K++ L E + +E EK++ DE
Sbjct: 1025 TLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDE 1084
Query: 267 LLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSK--MEESKALD 324
L + + S++ + + + ++ Q ++ L +E +E I+ + E + D
Sbjct: 1085 KLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1144
Query: 325 SSRDM--CLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQ 382
SR++ LE + E N+K + QK L + +++ ++K
Sbjct: 1145 LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHAD 1204
Query: 383 IDTVFGEK 390
GE+
Sbjct: 1205 SVAELGEQ 1212
Score = 34.7 bits (78), Expect = 0.30
Identities = 39/211 (18%), Positives = 91/211 (43%), Gaps = 17/211 (8%)
Query: 23 IEKQRKELQLLIGELKDRDKELNDMV--AVHQQQLLSWEEDRQKVL-----TLEERCSKL 75
I + + E++ ++ E ++ +++ + A + L E+D L +E+ L
Sbjct: 1740 ISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL 1799
Query: 76 EGELHKRTEI-IRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEAR 134
+ L + ++ ++ K+++ LE+ E + ++ Q + E + ++L +
Sbjct: 1800 QLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQ 1859
Query: 135 NETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDA 194
E ++ L V +LQA+ +K + EA KF+ L+H L +A
Sbjct: 1860 TEEDRKNILRLQDLVDKLQAK-------VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEA 1912
Query: 195 KMAETCIVKEKQDYKQKLKALKIEVNKLKED 225
+ E + E Q K ++K+ ++ + E+
Sbjct: 1913 E--ERADIAESQVNKLRVKSREVHTKVISEE 1941
Score = 32.0 bits (71), Expect = 1.9
Identities = 23/111 (20%), Positives = 53/111 (47%), Gaps = 11/111 (9%)
Query: 15 GSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQL----LSWEEDRQKVLTLEE 70
G + +I +E + +EL+ + + R+ E + H++++ EEDR+ +L L++
Sbjct: 1813 GGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQD 1872
Query: 71 RCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKA 121
KL+ + ++S ++ + E +K Q +L+E ++A
Sbjct: 1873 LVDKLQAK-------VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERA 1916
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 72.8 bits (177), Expect = 1e-12
Identities = 83/397 (20%), Positives = 173/397 (43%), Gaps = 47/397 (11%)
Query: 11 RQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQL--LSWEEDRQKVLT- 67
++ +E ++ + ++ L I +L K L + HQQ L L EED+ LT
Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQE---AHQQTLDDLQAEEDKVNTLTK 1028
Query: 68 ----LEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATH 123
LE++ LEG L + ++ L + + LE + Q ++ + + Q++ +K
Sbjct: 1029 AKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKK 1088
Query: 124 SSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGK 183
+L+++ E ++L ++ +LQAR + L I+ + +A +D S +
Sbjct: 1089 KEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRE 1148
Query: 184 FKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRL 243
+ + L +A A + ++ K + E K++ DL E T + +E +R
Sbjct: 1149 LEEISERLEEAGGATSAQIEMN-------KKREAEFQKMRRDLEEATLQ-HEATAATLRK 1200
Query: 244 KQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNV 303
K S E ++ D L + K K E+ SE+ + ++ L NV
Sbjct: 1201 KHADS--------VAELGEQIDNLQRV-KQKLEKEKSEM----------KMEIDDLASNV 1241
Query: 304 E-------NSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQ 356
E N +++ + + ++ E K+ + + ++DL + ++ E + S D+
Sbjct: 1242 ETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGR--LQTESGEFSRQLDE 1299
Query: 357 KFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVI 393
K EA++ Q +R ++ + +E K+Q++ K+ +
Sbjct: 1300 K-EALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNAL 1335
Score = 58.2 bits (139), Expect = 3e-08
Identities = 74/368 (20%), Positives = 156/368 (42%), Gaps = 32/368 (8%)
Query: 55 LLSWEEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKAL--ESNQMECQT------- 105
LL E +++ T++E K++ EL K + L +K+ L E N ++ Q
Sbjct: 845 LLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGL 904
Query: 106 --------ALQKTQLQLQ----EMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQ 153
L KT++QL+ E+ ++A ++ +L A+ L + EL + L+
Sbjct: 905 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 964
Query: 154 ---AREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQ 210
A+ + + K K++ E + + + K + AL++A ++ ++D
Sbjct: 965 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1024
Query: 211 KLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKS---CLHDELLFTVEREKRK-DE 266
L KI++ + +DL + + R ++ R K++ L E + +E EK++ DE
Sbjct: 1025 TLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDE 1084
Query: 267 LLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSK--MEESKALD 324
L + + S++ + + + ++ Q ++ L +E +E I+ + E + D
Sbjct: 1085 KLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1144
Query: 325 SSRDM--CLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQ 382
SR++ LE + E N+K + QK L + +++ ++K
Sbjct: 1145 LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHAD 1204
Query: 383 IDTVFGEK 390
GE+
Sbjct: 1205 SVAELGEQ 1212
Score = 34.7 bits (78), Expect = 0.30
Identities = 39/211 (18%), Positives = 91/211 (43%), Gaps = 17/211 (8%)
Query: 23 IEKQRKELQLLIGELKDRDKELNDMV--AVHQQQLLSWEEDRQKVL-----TLEERCSKL 75
I + + E++ ++ E ++ +++ + A + L E+D L +E+ L
Sbjct: 1740 ISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL 1799
Query: 76 EGELHKRTEI-IRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEAR 134
+ L + ++ ++ K+++ LE+ E + ++ Q + E + ++L +
Sbjct: 1800 QLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQ 1859
Query: 135 NETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDA 194
E ++ L V +LQA+ +K + EA KF+ L+H L +A
Sbjct: 1860 TEEDRKNILRLQDLVDKLQAK-------VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEA 1912
Query: 195 KMAETCIVKEKQDYKQKLKALKIEVNKLKED 225
+ E + E Q K ++K+ ++ + E+
Sbjct: 1913 E--ERADIAESQVNKLRVKSREVHTKVISEE 1941
Score = 32.0 bits (71), Expect = 1.9
Identities = 23/111 (20%), Positives = 53/111 (47%), Gaps = 11/111 (9%)
Query: 15 GSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQL----LSWEEDRQKVLTLEE 70
G + +I +E + +EL+ + + R+ E + H++++ EEDR+ +L L++
Sbjct: 1813 GGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQD 1872
Query: 71 RCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKA 121
KL+ + ++S ++ + E +K Q +L+E ++A
Sbjct: 1873 LVDKLQAK-------VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERA 1916
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 71.2 bits (173), Expect = 3e-12
Identities = 79/391 (20%), Positives = 165/391 (42%), Gaps = 26/391 (6%)
Query: 11 RQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQL--LSWEEDRQKVLT- 67
++ +E ++ + ++ L I +L K L + HQQ L L EED+ LT
Sbjct: 970 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQE---AHQQTLDDLQAEEDKVNTLTK 1026
Query: 68 ----LEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATH 123
LE++ LEG L + +I L + + LE + Q + + Q++ +K
Sbjct: 1027 AKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKK 1086
Query: 124 SSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGK 183
L+++ E ++L ++ +LQAR + L I+ + +A +D S +
Sbjct: 1087 KEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRE 1146
Query: 184 FKMLEHALRDA-----------KMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTE 232
+ + L +A K E K ++D ++ + L++ + E
Sbjct: 1147 LEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAE 1206
Query: 233 NNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHN-LRQIYVK 291
EQ + + R+KQ+ E+ ++ E ++ AK E+ L + L +I K
Sbjct: 1207 LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTK 1266
Query: 292 QQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKS 351
++ + +N + + + ++ E S+ LD +D +S L + E+ ++
Sbjct: 1267 EEEQQRLIN---DLTAQRARLQTESGEYSRQLD-EKDTLVSQLSRGKQAFTQQIEELKRQ 1322
Query: 352 LFKDQKFEAMLVQQNRSDKSSCDECKEKKQQ 382
L ++ K ++ L +S + CD +E+ ++
Sbjct: 1323 LEEEIKAKSALAHALQSSRHDCDLLREQYEE 1353
Score = 54.7 bits (130), Expect = 3e-07
Identities = 101/475 (21%), Positives = 192/475 (40%), Gaps = 60/475 (12%)
Query: 19 EISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKV----LTLEERCSK 74
E++ E +RKEL+ + L +L V L EE ++ + LE + +
Sbjct: 866 ELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKE 925
Query: 75 LEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQ--EMAQKATHSSL--LSED 130
+ EI LT K + LE E + + +L L E + AT + + L+E+
Sbjct: 926 VTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 985
Query: 131 LEARNETLSNTLVELSA-------QVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGK 183
+ +ET++ E A + LQA E + T+ K K I+ + D G
Sbjct: 986 MAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAK----IKLEQQVDDLEGS 1041
Query: 184 FKM-------LEHALR----DAKMAETC---IVKEKQDYKQKLKALKIEVNKLKEDLNEK 229
+ LE A R D K+A+ I +KQ +KLK + E++ L+ + ++
Sbjct: 1042 LEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDE 1101
Query: 230 TTENNEQREEIIRLKQEKSCLHDEL----LFTVEREKRKDELLNIAKSKQERTNS----- 280
+ +++I L+ L +E+ + EK++ +L + ER
Sbjct: 1102 QALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1161
Query: 281 ----ELHNLRQI-YVKQQSDLQFLNFNVENSQELIQM--YDSKMEESKALDSSRDMCLSD 333
E++ R+ + K + DL+ E + ++ DS E + +D+ + +
Sbjct: 1162 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRV-KQK 1220
Query: 334 LENNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKS-- 391
LE ++ ++ + ++ K + L + R+ + E K K+++ + + +
Sbjct: 1221 LEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQ 1280
Query: 392 ---VITLSSIFTKDLVEKHNLPWSLG-GK----TQIEPENKITLCKIHTKSPKCH 438
+ T S +++ L EK L L GK QIE + +I KS H
Sbjct: 1281 RARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAH 1335
Score = 51.6 bits (122), Expect = 2e-06
Identities = 72/368 (19%), Positives = 153/368 (41%), Gaps = 32/368 (8%)
Query: 55 LLSWEEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKAL--ESNQMECQT------- 105
LL E +++ ++E K + EL K + L +K+ L E N ++ Q
Sbjct: 843 LLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSL 902
Query: 106 --------ALQKTQLQLQ----EMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQ 153
L KT++QL+ E+ ++A ++ +L A+ L + EL + L+
Sbjct: 903 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
Query: 154 ---AREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQ 210
A+ + + K K++ E + + + K + AL++A ++ ++D
Sbjct: 963 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1022
Query: 211 KLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKS---CLHDELLFTVEREKRK-DE 266
L KI++ + +DL + + R ++ R K++ L E +E +K++ DE
Sbjct: 1023 TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDE 1082
Query: 267 LLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSK--MEESKALD 324
L + + S++ + + + ++ Q ++ L +E +E I+ + E + D
Sbjct: 1083 KLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1142
Query: 325 SSRDM--CLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQ 382
SR++ LE + E N+K + QK L + +++ ++K
Sbjct: 1143 LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHAD 1202
Query: 383 IDTVFGEK 390
GE+
Sbjct: 1203 SVAELGEQ 1210
Score = 50.8 bits (120), Expect = 4e-06
Identities = 80/367 (21%), Positives = 147/367 (40%), Gaps = 57/367 (15%)
Query: 69 EERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLS 128
E+ + ++ E K E + K K LE + QLQ+Q A
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLA------ 903
Query: 129 EDLEARNETLSNTLVELSAQVGQLQAR---EQALTTMIKLKDKDIIEAVNHIADCSGKFK 185
D E R + L T ++L A++ ++ R E+ + + K + + + +CS
Sbjct: 904 -DAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLED------ECSE--- 953
Query: 186 MLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQ 245
L+ + D ++ + KEK + K+K L E+ L E + + T E +E
Sbjct: 954 -LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQE------- 1005
Query: 246 EKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVEN 305
H + L ++ E+ K L AK K E+ +L + K + DL+ +E
Sbjct: 1006 ----AHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEG 1061
Query: 306 SQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQ------KSLFKDQKFE 359
+L Q +S M D+EN+ ++D K +K + +S +D++
Sbjct: 1062 DLKLAQ--ESTM---------------DIENDKQQLDEKLKKKEFEMSGLQSKIEDEQAL 1104
Query: 360 AMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSIFTKDLVEKHNLPWSLGGKT-- 417
M +Q+ + + E E++ + + K+ S + +++L E GG T
Sbjct: 1105 GMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL-SRELEEISERLEEAGGATSA 1163
Query: 418 QIEPENK 424
QIE K
Sbjct: 1164 QIEMNKK 1170
Score = 46.2 bits (108), Expect = 1e-04
Identities = 88/403 (21%), Positives = 162/403 (40%), Gaps = 68/403 (16%)
Query: 17 EVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLE 76
E E S ++ K L++ + EL E++ +A +++ + R + +E S L+
Sbjct: 1550 EAEASLEHEEGKILRIQL-ELNQVKSEVDRKIAEKDEEIDQMK--RNHIRIVESMQSTLD 1606
Query: 77 GELHKRTEIIRSLTKKVKALESNQMECQ-------------------TALQKTQLQL--- 114
E+ R + IR L KK++ + N+ME Q L+ TQL L
Sbjct: 1607 AEIRSRNDAIR-LKKKMEG-DLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDA 1664
Query: 115 --------QEMAQKATHSSLLSEDLEARNETLSNT----------LVELSAQVGQLQARE 156
+++A ++LL ++E TL T L++ S +V L +
Sbjct: 1665 LRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQN 1724
Query: 157 QALTTMIKLKDKDIIEAVNHIADCSGKFKMLEH----ALRD-AKMAETCIVKEKQDYKQK 211
+L K + DI + + D + + E A+ D A MAE +K++QD
Sbjct: 1725 TSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEE--LKKEQDTSAH 1782
Query: 212 LKALKIEVNKLKEDLNEKTTENNE-----QREEIIRLKQEKSCLHDELLFTVEREKRKDE 266
L+ +K + + +DL + E + +++I +L+ L E VE E++++
Sbjct: 1783 LERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGE----VESEQKRNV 1838
Query: 267 LLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALD-- 324
K ER EL + K LQ L V+ Q ++ Y + EE++
Sbjct: 1839 EAVKGLRKHERKVKELTYQTEEDRKNILRLQDL---VDKLQAKVKSYKRQAEEAEEQSNV 1895
Query: 325 --SSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQ 365
S +LE + DI + K K ++ ++ +
Sbjct: 1896 NLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKIISE 1938
Score = 34.3 bits (77), Expect = 0.39
Identities = 72/367 (19%), Positives = 150/367 (40%), Gaps = 53/367 (14%)
Query: 23 IEKQRKELQLLIGELKDRDKE----LNDMVAVHQQ-QLLSWEEDRQ---KVLTLEERCSK 74
+EK + L+ + E+K +++E +ND+ A + Q S E RQ K + +
Sbjct: 1249 LEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRG 1308
Query: 75 LEGELHKRTEIIRSLTKKVKA-------LESNQMECQTAL------QKTQLQLQEMAQKA 121
+ + E+ R L +++KA L+S++ +C Q+ + +LQ KA
Sbjct: 1309 KQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKA 1368
Query: 122 THS-----SLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNH 176
+ D R E L +L+ ++ + +A+ +K N
Sbjct: 1369 NSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNE 1428
Query: 177 IADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQ 236
+ D M++ +A A + K+++++ + L K + + +L E+
Sbjct: 1429 VEDL-----MIDVERTNAACA--ALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSL 1481
Query: 237 REEIIRLKQEKSCLHDELLFTVEREKR--KDELLNIAKSKQERTNSELHNLRQIYVKQQS 294
E+ ++K D+L T++RE + + E+ ++ + E +H L +I + +
Sbjct: 1482 STELFKIKNAYEESLDQLE-TLKRENKNLQQEISDLTEQIAEG-GKRIHELEKIKKQVEQ 1539
Query: 295 DLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFK 354
+ L +E ++ ++ EE K L LE N +K E ++K K
Sbjct: 1540 EKSELQAALEEAEASLE-----HEEGKIL-------RIQLELN----QVKSEVDRKIAEK 1583
Query: 355 DQKFEAM 361
D++ + M
Sbjct: 1584 DEEIDQM 1590
Score = 30.8 bits (68), Expect = 4.3
Identities = 24/130 (18%), Positives = 63/130 (48%), Gaps = 15/130 (11%)
Query: 15 GSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQL----LSWEEDRQKVLTLEE 70
G + +I +E + +EL+ + + R+ E + H++++ EEDR+ +L L++
Sbjct: 1811 GGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQD 1870
Query: 71 RCSKLEG----------ELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQK 120
KL+ E +++ + S ++++ E + E + + ++Q+ + +
Sbjct: 1871 LVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQH-ELEEAEERADIAESQVNKLRVKSR 1929
Query: 121 ATHSSLLSED 130
H+ ++SE+
Sbjct: 1930 EVHTKIISEE 1939
>gi|187761324 shootin1 isoform a [Homo sapiens]
Length = 631
Score = 69.7 bits (169), Expect = 8e-12
Identities = 78/362 (21%), Positives = 158/362 (43%), Gaps = 37/362 (10%)
Query: 39 DRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKALES 98
D +K+L + ++ +Q + +E+ R + +E+C K+ E R E ++ L + K S
Sbjct: 5 DEEKQLQLITSLKEQAIGEYEDLRAENQKTKEKCDKIRQE---RDEAVKKLEEFQKI--S 59
Query: 99 NQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQA 158
+ + + + L++++ +++ + L+ L N+TL + A++G
Sbjct: 60 HMVIEEVNFMQNHLEIEKTCRESAEA--LATKLNKENKTLKRISMLYMAKLGP-----DV 112
Query: 159 LTTMIKLKDKDIIEAVNHIAD------CSGKFKMLEHALRDAKMAETCIVKEKQDYKQKL 212
+T I + D+D + A+ C + K L + + + + E ++ K KL
Sbjct: 113 ITEEINIDDEDSTTDTDGAAETCVSVQCQKQIKELRDQIVSVQEEKKILAIELENLKSKL 172
Query: 213 KALKIEVNKLKED---LNEKTTENNEQREEIIRLKQEKSCLHDELLFTVERE----KRKD 265
+ EVNK+K++ LN + E + E+ R+ ++E+ +E E K+ +
Sbjct: 173 VEVIEEVNKVKQEKTVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRKKAE 232
Query: 266 ELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDS 325
+Q + + H L Q + Q L+ L+ N + +Q+L + ++ K L+
Sbjct: 233 SFAQEMFIEQNKLKRQSHLLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELE- 291
Query: 326 SRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRSDKS-----SCDECKEKK 380
LEN +I K Q L ++ K E L QN +K+ S DE +++
Sbjct: 292 ------EQLENETLHKEIHNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQKRV 345
Query: 381 QQ 382
Q
Sbjct: 346 NQ 347
>gi|50511340 shootin1 isoform b [Homo sapiens]
Length = 456
Score = 69.7 bits (169), Expect = 8e-12
Identities = 78/362 (21%), Positives = 158/362 (43%), Gaps = 37/362 (10%)
Query: 39 DRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKALES 98
D +K+L + ++ +Q + +E+ R + +E+C K+ E R E ++ L + K S
Sbjct: 5 DEEKQLQLITSLKEQAIGEYEDLRAENQKTKEKCDKIRQE---RDEAVKKLEEFQKI--S 59
Query: 99 NQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQA 158
+ + + + L++++ +++ + L+ L N+TL + A++G
Sbjct: 60 HMVIEEVNFMQNHLEIEKTCRESAEA--LATKLNKENKTLKRISMLYMAKLGP-----DV 112
Query: 159 LTTMIKLKDKDIIEAVNHIAD------CSGKFKMLEHALRDAKMAETCIVKEKQDYKQKL 212
+T I + D+D + A+ C + K L + + + + E ++ K KL
Sbjct: 113 ITEEINIDDEDSTTDTDGAAETCVSVQCQKQIKELRDQIVSVQEEKKILAIELENLKSKL 172
Query: 213 KALKIEVNKLKED---LNEKTTENNEQREEIIRLKQEKSCLHDELLFTVERE----KRKD 265
+ EVNK+K++ LN + E + E+ R+ ++E+ +E E K+ +
Sbjct: 173 VEVIEEVNKVKQEKTVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRKKAE 232
Query: 266 ELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDS 325
+Q + + H L Q + Q L+ L+ N + +Q+L + ++ K L+
Sbjct: 233 SFAQEMFIEQNKLKRQSHLLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELE- 291
Query: 326 SRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRSDKS-----SCDECKEKK 380
LEN +I K Q L ++ K E L QN +K+ S DE +++
Sbjct: 292 ------EQLENETLHKEIHNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQKRV 345
Query: 381 QQ 382
Q
Sbjct: 346 NQ 347
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 69.3 bits (168), Expect = 1e-11
Identities = 86/423 (20%), Positives = 173/423 (40%), Gaps = 47/423 (11%)
Query: 24 EKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGELHKRT 83
E+ + EL+ E + EL + +++ L E +++ L+E S L +L
Sbjct: 1461 EESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSG 1520
Query: 84 EIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSL------------LSEDL 131
+ I L K K LE+ +ME Q+AL++ + L+ K + L L+E
Sbjct: 1521 KTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1580
Query: 132 EARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDK----------DIIEAVNHIADCS 181
E + N L + + L A ++ +++K K + A A+
Sbjct: 1581 EEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQ 1640
Query: 182 GKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNE-----KTTENNEQ 236
+ K L+ L+D ++ V+ D K+ + ++ N L+ +L E + TE + +
Sbjct: 1641 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRK 1700
Query: 237 --REEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQS 294
+E+I + LH + + ++K+ D L+ +++ E E N + K +
Sbjct: 1701 LAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAIT 1760
Query: 295 DLQFLNFNVENSQEL---IQMYDSKMEES-----KALDSSRDMCLSDLENNHPKVDIKRE 346
D + ++ Q+ ++ ME++ LD + + L + K++ +
Sbjct: 1761 DAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 1820
Query: 347 KNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSIFTKDLVEK 406
+ + L +QK A V+ R E + K+ T K+++ L +DLV+K
Sbjct: 1821 ELENELEAEQKRNAESVKGMRK-----SERRIKELTYQTEEDRKNLLRL-----QDLVDK 1870
Query: 407 HNL 409
L
Sbjct: 1871 LQL 1873
Score = 62.4 bits (150), Expect = 1e-09
Identities = 87/410 (21%), Positives = 174/410 (42%), Gaps = 73/410 (17%)
Query: 11 RQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQL--LSWEEDRQKVLT- 67
++ +E ++ + ++ L +I +L K L + HQQ L L EED+ LT
Sbjct: 966 KEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQE---AHQQALDDLQAEEDKVNTLTK 1022
Query: 68 ----LEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATH 123
LE++ LEG L + ++ L + + LE + K T
Sbjct: 1023 AKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGD-------------------LKLTQ 1063
Query: 124 SSLLSEDLEARNETLSNTLVELSAQVGQLQAR---EQALTTMIKLKDKDIIEAVNHIADC 180
S++ DLE + L L + ++ L AR EQAL + ++ K K++
Sbjct: 1064 ESIM--DLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKEL---------- 1111
Query: 181 SGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTT---ENNEQR 237
+ + LE L + A + K + D ++L+ E+++ E+ T+ E N++R
Sbjct: 1112 QARIEELEEELEAERTARAKVEKLRSDLSRELE----EISERLEEAGGATSVQIEMNKKR 1167
Query: 238 E---EIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQS 294
E + +R E++ L E R+K D + + + L ++Q K++S
Sbjct: 1168 EAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQ-----IDNLQRVKQKLEKEKS 1222
Query: 295 ----DLQFLNFNVE-------NSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDI 343
+L + N+E N +++ + + +M E ++ ++DL + K +
Sbjct: 1223 EFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAK--L 1280
Query: 344 KREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVI 393
+ E + S D+K EA++ Q R + + ++ K+Q++ K+ +
Sbjct: 1281 QTENGELSRQLDEK-EALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNAL 1329
Score = 52.4 bits (124), Expect = 1e-06
Identities = 65/288 (22%), Positives = 118/288 (40%), Gaps = 44/288 (15%)
Query: 24 EKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKV----LTLEERCSKLEGEL 79
E +RKEL+ + L +L V Q L EE ++ + LE + ++ L
Sbjct: 867 EARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERL 926
Query: 80 HKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQ--EMAQKATHSSL--LSEDLEARN 135
E+ LT K + LE E + + +L L E + AT + + L+E++ +
Sbjct: 927 EDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLD 986
Query: 136 ETLSNTLVELSA-------QVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKM-- 186
E ++ E A + LQA E + T+ K K ++ + D G +
Sbjct: 987 EIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAK----VKLEQQVDDLEGSLEQEK 1042
Query: 187 -----LEHALR----DAKMAETCIV---KEKQDYKQKLKALKIEVNKLKEDLNEKTTENN 234
LE A R D K+ + I+ +KQ ++LK E+N L + ++ +
Sbjct: 1043 KVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGS 1102
Query: 235 EQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSEL 282
+ ++++ L+ L +EL E A++K E+ S+L
Sbjct: 1103 QLQKKLKELQARIEELEEEL-----------EAERTARAKVEKLRSDL 1139
Score = 50.4 bits (119), Expect = 5e-06
Identities = 73/347 (21%), Positives = 153/347 (44%), Gaps = 35/347 (10%)
Query: 55 LLSWEEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQL 114
LL E +++ +++E ++L+ L K + L +K+ +L + + Q +Q Q L
Sbjct: 839 LLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 898
Query: 115 QEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDI---- 170
+ ++ LEA+ + ++ L + +L A+++ L +DI
Sbjct: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958
Query: 171 -----IEAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKED 225
+E H + K E A D +A+ + KEK KAL+ + +D
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAK--LTKEK-------KALQEAHQQALDD 1009
Query: 226 LNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNL 285
L + + N + ++L+Q+ D+L ++E+EK+ L AK K E +L
Sbjct: 1010 LQAEEDKVNTLTKAKVKLEQQV----DDLEGSLEQEKKVRMDLERAKRKLE---GDLKLT 1062
Query: 286 RQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKR 345
++ + ++D Q L+ ++ + ++++E+ +AL S L +L+ +++ +
Sbjct: 1063 QESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Query: 346 EKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSV 392
E + + K V++ RSD S E +E ++++ G SV
Sbjct: 1123 EAERTARAK--------VEKLRSDLSR--ELEEISERLEEAGGATSV 1159
Score = 40.8 bits (94), Expect = 0.004
Identities = 65/391 (16%), Positives = 158/391 (40%), Gaps = 38/391 (9%)
Query: 11 RQNIGSEVEISTIEKQRKELQLLIGELKDR--DKELNDMVAVHQQQLLSWEEDRQKVLTL 68
+ + +E+E ++ +R + K R DK L + +++ E +++ +L
Sbjct: 1418 KHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSL 1477
Query: 69 EERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLS 128
KL+ + E + + ++ K L+ + L + + E+ + +
Sbjct: 1478 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK-------VR 1530
Query: 129 EDLEARNETLSNTLVELSAQVGQLQA---REQALTTMIKLK-DKDIIEAVNHIADCSGKF 184
+ LEA L + L E A + + R Q IK + ++ + E +
Sbjct: 1531 KQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNH 1590
Query: 185 KMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTE----NNEQREEI 240
+ +L+ + AET + + +AL+++ K++ DLNE + N E
Sbjct: 1591 LRVVDSLQTSLDAET---------RSRNEALRVK-KKMEGDLNEMEIQLSHANRMAAEAQ 1640
Query: 241 IRLKQEKSCLHDELLFTVEREKRKDEL---LNIAKSKQERTNSELHNLRQIYVKQQSDLQ 297
++K +S L D + + + D+L + I + + +EL LR + + + +
Sbjct: 1641 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRK 1700
Query: 298 FLNFNVENSQELIQMYDSK----MEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLF 353
+ + E +Q+ S+ + + K +D+ +++E + EK +K++
Sbjct: 1701 LAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAIT 1760
Query: 354 KDQKFEAMLVQQNRSDKSSCDECKEKKQQID 384
AM+ ++ + ++ + + K+ ++
Sbjct: 1761 D----AAMMAEELKKEQDTSAHLERMKKNME 1787
>gi|188528616 testis specific, 10 [Homo sapiens]
Length = 698
Score = 69.3 bits (168), Expect = 1e-11
Identities = 103/481 (21%), Positives = 205/481 (42%), Gaps = 82/481 (17%)
Query: 20 ISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGEL 79
IST+EK+ K L + D + EL A + L +E + + + +K + EL
Sbjct: 172 ISTVEKEMKSLAR---KAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKKYEL 228
Query: 80 HKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQ-----------KATHSSLLS 128
E I L +K+ + + + L ++A+ K+ + + L
Sbjct: 229 QLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLNDLAKEKECLQACLDKKSENIASLG 288
Query: 129 EDLEARNETLS---NTLVELSAQVGQ----LQAREQALTTMIK------------LKDKD 169
E L + +T+S N + E+ Q L EQ ++ M + +++D
Sbjct: 289 ESLAMKEKTISGMKNIIAEMEQASRQCTEALIVCEQDVSRMRRQLDETNDELAQIARERD 348
Query: 170 IIEAVN-HIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNE 228
I+ N ++ + K K AL K+ +T E D KQK++ +EVNKLK L
Sbjct: 349 ILAHDNDNLQEQFAKAKQENQAL-SKKLNDTH--NELNDIKQKVQDTNLEVNKLKNILKS 405
Query: 229 KTTENNEQREEIIRLKQEKSCLHDEL-------------LFTVERE--KRKDELLNIAKS 273
+ +EN + E++ + ++ ++ L T E E + K+++ ++ +
Sbjct: 406 EESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLELITAEAEGNRLKEKVDSLNRE 465
Query: 274 KQERTN------SELHNLRQIYVKQQSDLQFLNF-------NVENSQELIQMYDSKME-- 318
++ N S++ L + VK + +LQ + F ++ +++EL DS E
Sbjct: 466 VEQHLNAERSYKSQISTLHKSVVKMEEELQKVQFEKVSALADLSSTRELCIKLDSSKELL 525
Query: 319 --ESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDEC 376
+ A D +M ++L++ H ++++ R + Q EA+LV + S
Sbjct: 526 NRQLVAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNLEALLVANRDKEYQSQIAL 585
Query: 377 KEKKQQIDTVFGEKSVITLS----SIFTKDLVEKHNLPWSLGGKTQIEPENKITLCKIHT 432
+EK+ +I + K + L+ +I ++D+ + N+ TQ+E + IT ++ T
Sbjct: 586 QEKESEIQLL---KEHLCLAENKMAIQSRDVAQFRNV------VTQLEADLDITKRQLGT 636
Query: 433 K 433
+
Sbjct: 637 E 637
Score = 43.1 bits (100), Expect = 8e-04
Identities = 62/304 (20%), Positives = 120/304 (39%), Gaps = 49/304 (16%)
Query: 59 EEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKA-LESNQMECQTALQKTQLQLQEM 117
E +R T R + L +R +I + KA LE E + + + E
Sbjct: 102 ETERDVAFTDLRRMTTERDSLRERLKIAQETAFNEKAHLEQRIEELECTVHNLDDERMEQ 161
Query: 118 AQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHI 177
T +E ++L+ ++ +++G+ +A +L + + +KD+ + H+
Sbjct: 162 MSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHL 221
Query: 178 ADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQR 237
A K+ Y+ +L KI L E ++ T +N QR
Sbjct: 222 A--------------------------KKKYELQLTQEKIMC--LDEKIDNFTRQNIAQR 253
Query: 238 EEII-------RLKQEKSCLHDELLFTVEREKRKDELLNIAKS--KQERTNSELHNLRQI 288
EEI L +EK CL L +K+ + + ++ +S +E+T S + N+ I
Sbjct: 254 EEISILGGTLNDLAKEKECLQACL------DKKSENIASLGESLAMKEKTISGMKNI--I 305
Query: 289 YVKQQSDLQFLNFNVENSQELIQM---YDSKMEESKALDSSRDMCLSDLENNHPKVDIKR 345
+Q+ Q + Q++ +M D +E + RD+ D +N + +
Sbjct: 306 AEMEQASRQCTEALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDNDNLQEQFAKAK 365
Query: 346 EKNQ 349
++NQ
Sbjct: 366 QENQ 369
Score = 31.2 bits (69), Expect = 3.3
Identities = 48/221 (21%), Positives = 89/221 (40%), Gaps = 51/221 (23%)
Query: 185 KMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLK 244
++L+ RD + + + K Y++ L ++ V LK + ++ + +EEI RL+
Sbjct: 24 ELLKTTTRDREELKCMLEK----YERHLAEIQGNVKVLKSERDKIFLLYEQAQEEITRLR 79
Query: 245 QE--KSCLHDE------LLFTVEREK------------RKDELLNIAKSKQERTNSE--- 281
+E KSC + +L VE E+ +D L K QE +E
Sbjct: 80 REMMKSCKSPKSTTAHAILRRVETERDVAFTDLRRMTTERDSLRERLKIAQETAFNEKAH 139
Query: 282 -----------LHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMC 330
+HNL ++Q S++ + + ++ + K KA+D+ ++
Sbjct: 140 LEQRIEELECTVHNLDDERMEQMSNMTLMKETISTVEK-----EMKSLARKAMDTESELG 194
Query: 331 LSDLENNHPKVDIKREKNQKSLFKDQ------KFEAMLVQQ 365
ENN + + E +K L Q K+E L Q+
Sbjct: 195 RQKAENN--SLRLLYENTEKDLSDTQRHLAKKKYELQLTQE 233
>gi|13376858 testis specific, 10 [Homo sapiens]
Length = 698
Score = 69.3 bits (168), Expect = 1e-11
Identities = 103/481 (21%), Positives = 205/481 (42%), Gaps = 82/481 (17%)
Query: 20 ISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGEL 79
IST+EK+ K L + D + EL A + L +E + + + +K + EL
Sbjct: 172 ISTVEKEMKSLAR---KAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKKYEL 228
Query: 80 HKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQ-----------KATHSSLLS 128
E I L +K+ + + + L ++A+ K+ + + L
Sbjct: 229 QLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLNDLAKEKECLQACLDKKSENIASLG 288
Query: 129 EDLEARNETLS---NTLVELSAQVGQ----LQAREQALTTMIK------------LKDKD 169
E L + +T+S N + E+ Q L EQ ++ M + +++D
Sbjct: 289 ESLAMKEKTISGMKNIIAEMEQASRQCTEALIVCEQDVSRMRRQLDETNDELAQIARERD 348
Query: 170 IIEAVN-HIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNE 228
I+ N ++ + K K AL K+ +T E D KQK++ +EVNKLK L
Sbjct: 349 ILAHDNDNLQEQFAKAKQENQAL-SKKLNDTH--NELNDIKQKVQDTNLEVNKLKNILKS 405
Query: 229 KTTENNEQREEIIRLKQEKSCLHDEL-------------LFTVERE--KRKDELLNIAKS 273
+ +EN + E++ + ++ ++ L T E E + K+++ ++ +
Sbjct: 406 EESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLELITAEAEGNRLKEKVDSLNRE 465
Query: 274 KQERTN------SELHNLRQIYVKQQSDLQFLNF-------NVENSQELIQMYDSKME-- 318
++ N S++ L + VK + +LQ + F ++ +++EL DS E
Sbjct: 466 VEQHLNAERSYKSQISTLHKSVVKMEEELQKVQFEKVSALADLSSTRELCIKLDSSKELL 525
Query: 319 --ESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDEC 376
+ A D +M ++L++ H ++++ R + Q EA+LV + S
Sbjct: 526 NRQLVAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNLEALLVANRDKEYQSQIAL 585
Query: 377 KEKKQQIDTVFGEKSVITLS----SIFTKDLVEKHNLPWSLGGKTQIEPENKITLCKIHT 432
+EK+ +I + K + L+ +I ++D+ + N+ TQ+E + IT ++ T
Sbjct: 586 QEKESEIQLL---KEHLCLAENKMAIQSRDVAQFRNV------VTQLEADLDITKRQLGT 636
Query: 433 K 433
+
Sbjct: 637 E 637
Score = 43.1 bits (100), Expect = 8e-04
Identities = 62/304 (20%), Positives = 120/304 (39%), Gaps = 49/304 (16%)
Query: 59 EEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKA-LESNQMECQTALQKTQLQLQEM 117
E +R T R + L +R +I + KA LE E + + + E
Sbjct: 102 ETERDVAFTDLRRMTTERDSLRERLKIAQETAFNEKAHLEQRIEELECTVHNLDDERMEQ 161
Query: 118 AQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHI 177
T +E ++L+ ++ +++G+ +A +L + + +KD+ + H+
Sbjct: 162 MSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHL 221
Query: 178 ADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQR 237
A K+ Y+ +L KI L E ++ T +N QR
Sbjct: 222 A--------------------------KKKYELQLTQEKIMC--LDEKIDNFTRQNIAQR 253
Query: 238 EEII-------RLKQEKSCLHDELLFTVEREKRKDELLNIAKS--KQERTNSELHNLRQI 288
EEI L +EK CL L +K+ + + ++ +S +E+T S + N+ I
Sbjct: 254 EEISILGGTLNDLAKEKECLQACL------DKKSENIASLGESLAMKEKTISGMKNI--I 305
Query: 289 YVKQQSDLQFLNFNVENSQELIQM---YDSKMEESKALDSSRDMCLSDLENNHPKVDIKR 345
+Q+ Q + Q++ +M D +E + RD+ D +N + +
Sbjct: 306 AEMEQASRQCTEALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDNDNLQEQFAKAK 365
Query: 346 EKNQ 349
++NQ
Sbjct: 366 QENQ 369
Score = 31.2 bits (69), Expect = 3.3
Identities = 48/221 (21%), Positives = 89/221 (40%), Gaps = 51/221 (23%)
Query: 185 KMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLK 244
++L+ RD + + + K Y++ L ++ V LK + ++ + +EEI RL+
Sbjct: 24 ELLKTTTRDREELKCMLEK----YERHLAEIQGNVKVLKSERDKIFLLYEQAQEEITRLR 79
Query: 245 QE--KSCLHDE------LLFTVEREK------------RKDELLNIAKSKQERTNSE--- 281
+E KSC + +L VE E+ +D L K QE +E
Sbjct: 80 REMMKSCKSPKSTTAHAILRRVETERDVAFTDLRRMTTERDSLRERLKIAQETAFNEKAH 139
Query: 282 -----------LHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMC 330
+HNL ++Q S++ + + ++ + K KA+D+ ++
Sbjct: 140 LEQRIEELECTVHNLDDERMEQMSNMTLMKETISTVEK-----EMKSLARKAMDTESELG 194
Query: 331 LSDLENNHPKVDIKREKNQKSLFKDQ------KFEAMLVQQ 365
ENN + + E +K L Q K+E L Q+
Sbjct: 195 RQKAENN--SLRLLYENTEKDLSDTQRHLAKKKYELQLTQE 233
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 68.6 bits (166), Expect = 2e-11
Identities = 79/381 (20%), Positives = 165/381 (43%), Gaps = 33/381 (8%)
Query: 11 RQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQL--LSWEEDRQKVLT- 67
++ +E ++ + ++ L+ I +L K L + HQQ L L EED+ L
Sbjct: 970 KEKHATENKVKNLSEEMTALEENISKLTKEKKSLQE---AHQQTLDDLQVEEDKVNGLIK 1026
Query: 68 ----LEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATH 123
LE++ LEG L + ++ L + + LE + Q ++ + Q++ +K
Sbjct: 1027 INAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKK 1086
Query: 124 SSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGK 183
L+A+ + ++ ++ +LQAR + L I+ + + +D + +
Sbjct: 1087 KEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARE 1146
Query: 184 FKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRL 243
+ + L +A A + ++ K + E K++ DL E T + +E +R
Sbjct: 1147 LEEISERLEEASGATSAQIEMN-------KKREAEFQKMRRDLEEATLQ-HEATAATLRK 1198
Query: 244 KQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNV 303
KQ S E ++ D L + K K E+ SE L+ S+++ L+ +
Sbjct: 1199 KQADS--------VAELGEQIDNLQRV-KQKLEKEKSE---LKMEIDDMASNIEALSKSK 1246
Query: 304 ENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLV 363
N + + + + E KA D + + DL N K ++ + + S ++K E+++
Sbjct: 1247 SNIERTCRTVEDQFSEIKAKDEQQTQLIHDL--NMQKARLQTQNGELSHRVEEK-ESLIS 1303
Query: 364 QQNRSDKSSCDECKEKKQQID 384
Q +S ++ + +E K+Q++
Sbjct: 1304 QLTKSKQALTQQLEELKRQME 1324
Score = 60.1 bits (144), Expect = 7e-09
Identities = 83/350 (23%), Positives = 155/350 (44%), Gaps = 27/350 (7%)
Query: 19 EISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEED-----RQKVLTLEERCS 73
E++ E +RKEL+ + L +L V + L+ EE + K+L LE +
Sbjct: 866 ELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKIL-LEAKVK 924
Query: 74 KLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQ--EMAQKATHSSL--LSE 129
+L L + E+ L K + LE + + +L L E + AT + + LSE
Sbjct: 925 ELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSE 984
Query: 130 DLEARNETLSNTLVELSAQVGQLQ-AREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLE 188
++ A E +S +L+ + LQ A +Q L + +DK VN + + K +
Sbjct: 985 EMTALEENIS----KLTKEKKSLQEAHQQTLDDLQVEEDK-----VNGLIKINAKLEQQT 1035
Query: 189 HALRDAKMAETCIVKEKQDYKQKLKA-LKIEVNKLKEDLNEKTTENNEQREEIIRLKQEK 247
L + E + + + K+KL+ LK+ + + N+K + +++ L Q +
Sbjct: 1036 DDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQ 1095
Query: 248 SCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDL-QFLNFNVENS 306
+ + DE + +++ +K+ EL + +E +E H LR KQ+SDL + L E
Sbjct: 1096 AKIDDEQVHSLQFQKKIKELQARIEELEEEIEAE-HTLRAKIEKQRSDLARELEEISERL 1154
Query: 307 QELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQ 356
+E +++E +K ++ DLE + ++ E +L K Q
Sbjct: 1155 EEASGATSAQIEMNKKREAEFQKMRRDLE----EATLQHEATAATLRKKQ 1200
Score = 50.8 bits (120), Expect = 4e-06
Identities = 67/298 (22%), Positives = 127/298 (42%), Gaps = 49/298 (16%)
Query: 55 LLSWEEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQL 114
LL E +++ T++E + + EL + + L +K+ +L +K LQL
Sbjct: 843 LLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQ---------EKNDLQL 893
Query: 115 QEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAV 174
Q Q T + + D E R E L + + L A+V +L R + M + +++
Sbjct: 894 Q--VQSETENLM---DAEERCEGLIKSKILLEAKVKELTERLEEEEEM----NSELVAKK 944
Query: 175 NHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENN 234
++ D K L+ + D ++ T + KEK + K+K L E+ L+E++++ T E
Sbjct: 945 RNLED---KCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKK 1001
Query: 235 EQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQS 294
+E H + L ++ E+ K L +K E+ +L + K ++
Sbjct: 1002 SLQE-----------AHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRA 1050
Query: 295 DLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSL 352
DL+ +E D KM + + DLEN+ +++ K +K + L
Sbjct: 1051 DLERAKRKLEG--------DLKMSQES---------IMDLENDKQQIEEKLKKKEFEL 1091
Score = 49.7 bits (117), Expect = 9e-06
Identities = 78/377 (20%), Positives = 163/377 (43%), Gaps = 40/377 (10%)
Query: 23 IEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGELHKR 82
+++ + EL+ E + EL M +++ + E R++ L+E S L ++ +
Sbjct: 1464 LDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAET 1523
Query: 83 TEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNETLSNTL 142
+ ++ K K +E + + Q AL++ + L+ K L +L L +
Sbjct: 1524 GKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQL---ELSQVKSELDRKV 1580
Query: 143 VELSAQVGQLQAREQ----ALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHAL--RDAKM 196
+E ++ QL+ Q AL +++ + + +A+ G +E L + +M
Sbjct: 1581 IEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQM 1640
Query: 197 AETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDEL-- 254
AET ++ L+ ++ ++ + L++ N + +E++ +++ L +EL
Sbjct: 1641 AET---------QKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEE 1691
Query: 255 ----LFTVEREKR--KDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQE 308
L ER +R + ELL+ A + + +S+ +L K ++D+ VENS
Sbjct: 1692 MKVALEQTERTRRLSEQELLD-ASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENS-- 1748
Query: 309 LIQMYDSKMEESKALDSSRDMCLSDLENNH-PKVDIKR-EKNQKSLFKDQKFEAMLVQQN 366
IQ + E++K + M +L+ ++R +KN + KD Q+
Sbjct: 1749 -IQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD--------LQH 1799
Query: 367 RSDKSSCDECKEKKQQI 383
R D++ K K+QI
Sbjct: 1800 RLDEAEQLALKGGKKQI 1816
Score = 47.8 bits (112), Expect = 3e-05
Identities = 77/388 (19%), Positives = 162/388 (41%), Gaps = 48/388 (12%)
Query: 16 SEVEISTIEKQRKELQLLIGELKDRDKELNDMVA-VHQQQLLSWEEDRQKVLTLEERCSK 74
+ +I +K+ E Q + +L++ + A + ++Q S E +++ L+ K
Sbjct: 1161 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQK 1220
Query: 75 LEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDL--- 131
LE E + I + ++AL ++ + + + Q E+ K + L DL
Sbjct: 1221 LEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQ 1280
Query: 132 ----EARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKML 187
+ +N LS+ + E + + QL +QALT ++ E + + + +
Sbjct: 1281 KARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLE-------ELKRQMEEETKAKNAM 1333
Query: 188 EHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEK 247
HAL+ ++ + +++E+ + +Q+ KA +L+ L++ +E + R K E
Sbjct: 1334 AHALQSSRH-DCDLLREQYEEEQEAKA------ELQRALSKANSEVAQWRT-----KYET 1381
Query: 248 SCLHDELLFTVEREKRKDEL---LNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVE 304
D + T E E+ K +L L A+ E NS+ +L + + Q +++ L ++E
Sbjct: 1382 ----DAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLE 1437
Query: 305 NSQELIQMYDSKME---------ESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKD 355
S D K + K +S ++ + E+ ++ + +N D
Sbjct: 1438 RSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVD 1497
Query: 356 QKFEAMLVQQNRSDKSSCDECKEKKQQI 383
Q L R +K+ +E + +QI
Sbjct: 1498 Q-----LETLRRENKNLQEEISDLTEQI 1520
>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
sapiens]
Length = 724
Score = 67.8 bits (164), Expect = 3e-11
Identities = 77/385 (20%), Positives = 164/385 (42%), Gaps = 34/385 (8%)
Query: 11 RQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEE 70
+QN+ + + + RK E + DK+L + + L +++ LE
Sbjct: 51 KQNLNVDKDTTLPASARKVKSSESKESQKNDKDLKILEKEIRVLLQERGAQDRRIQDLET 110
Query: 71 RCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSED 130
K+E L+ SL+ LE +E + + + E + L E
Sbjct: 111 ELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLEL 170
Query: 131 LEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHA 190
++ RN+ ++ + A+++ + +++ + + E+ IA GK +E
Sbjct: 171 MKLRNKR--------ETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKE 222
Query: 191 LRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCL 250
D K +ET ++ +Y +++ +V K K D+ + E+ +EI+ LKQ L
Sbjct: 223 KIDEK-SET---EKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQS---L 275
Query: 251 HDELLFTVER-----------EKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFL 299
+ ++ ++ EK K++ +N + E N+E+ NL+Q ++ +Q + + L
Sbjct: 276 EENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKL 335
Query: 300 NFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPK-VDIKREKNQKSLFKDQKF 358
Q+ +Q+ DS +++ K L SS L + K ++ E+ +++L + K
Sbjct: 336 ------QQKELQI-DSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKL 388
Query: 359 EAMLVQQNRSDKSSCDECKEKKQQI 383
+ Q R K +E K + +++
Sbjct: 389 QQKEEQAERLVKQLEEEAKSRAEEL 413
Score = 50.1 bits (118), Expect = 7e-06
Identities = 81/370 (21%), Positives = 156/370 (42%), Gaps = 44/370 (11%)
Query: 17 EVEISTIEKQRKEL-----QLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEER 71
E++I ++ +Q KEL Q L ++ KE N +Q L ++ +QK E
Sbjct: 339 ELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERL 398
Query: 72 CSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDL 131
+LE E R E ++ L +K+K E+ +L++ + T ++LL L
Sbjct: 399 VKQLEEEAKSRAEELKLLEEKLKGKEA--------------ELEKSSAAHTQATLL---L 441
Query: 132 EARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHAL 191
+ + +++ +L +++AQ +A + +KL++ + E A + ++H +
Sbjct: 442 QEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKA---AKAGKNAEDVQHQI 498
Query: 192 RDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLH 251
+ + V+ D + K + E+ ++ +K T+ Q LKQ++
Sbjct: 499 LATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQ------LKQQEEDFR 552
Query: 252 DELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQS-DLQFLNFNVENSQELI 310
+L + E RK E N E N ++Y K + LQ F VE Q L+
Sbjct: 553 KQL---EDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAFEVE-KQALL 608
Query: 311 QMYDSKMEESKALDSSRDMCLSDLENNHPKVDIK---REKNQKSLFKDQ--KFEAMLVQQ 365
+ + E+ L+ RD L + + K IK + K++ S K + K L ++
Sbjct: 609 NEHGAAQEQ---LNKIRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRCQLAKK 665
Query: 366 NRSDKSSCDE 375
+S+ +E
Sbjct: 666 KQSETKLQEE 675
Score = 38.5 bits (88), Expect = 0.021
Identities = 57/236 (24%), Positives = 107/236 (45%), Gaps = 39/236 (16%)
Query: 28 KELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQK----VLTLEERCSKLEGELHKRT 83
++L+L L+++ + Q Q+L+ E Q+ +L L+ + + E E+
Sbjct: 471 EDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIK--- 527
Query: 84 EIIRSLTKKVKALESNQMECQTALQKTQLQLQE--MAQKATHSSLLSEDLEARN---ETL 138
EI S +K+ L+ NQ++ Q + QL+ +E A+K ++ L+E++ E L
Sbjct: 528 EITVSFLQKITDLQ-NQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEEL 586
Query: 139 SNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMAE 198
N Q+ + +QAL + E +N I D K +L H
Sbjct: 587 YNKTKPFQLQLDAFEVEKQALLN----EHGAAQEQLNKIRDSYAK--LLGH--------- 631
Query: 199 TCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDEL 254
Q+ KQK+K V KLK++ ++ +E ++ R ++ + KQ ++ L +EL
Sbjct: 632 -------QNLKQKIK----HVVKLKDENSQLKSEVSKLRCQLAKKKQSETKLQEEL 676
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 67.8 bits (164), Expect = 3e-11
Identities = 74/369 (20%), Positives = 158/369 (42%), Gaps = 23/369 (6%)
Query: 11 RQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQL--LSWEEDRQKVLTL 68
+Q E + +E Q ++L+ + ++ +D + + + +L +S E + QK L L
Sbjct: 814 QQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQK-LEL 872
Query: 69 EERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLS 128
+ + ++L+ L +R + +L ALES + +T L++T + +E Q T
Sbjct: 873 KRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHR--- 929
Query: 129 EDLEARNETLSNT---LVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFK 185
++++ + + L N+ + +L Q+ QL L K + EA +
Sbjct: 930 DEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRS 989
Query: 186 MLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQ 245
++H R+ E + +KQ ++ALK L+E + + N+E E+ + +
Sbjct: 990 EVDHLRREITEREMQLTSQKQT----MEALKTTCTMLEEQVMDLEALNDELLEKERQWEA 1045
Query: 246 EKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVEN 305
+S L DE R + +L+ K + R + + RQ+ E+
Sbjct: 1046 WRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELAVK---------EH 1096
Query: 306 SQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQ 365
E++ + + E+ +S D L+DLE H +++ Q+ L +++ + L+++
Sbjct: 1097 KAEILALQQALKEQKLKAESLSDK-LNDLEKKHAMLEMNARSLQQKLETERELKQRLLEE 1155
Query: 366 NRSDKSSCD 374
+ D
Sbjct: 1156 QAKLQQQMD 1164
Score = 55.5 bits (132), Expect = 2e-07
Identities = 85/411 (20%), Positives = 176/411 (42%), Gaps = 74/411 (18%)
Query: 18 VEISTIEKQRKELQL----LIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCS 73
VE +E++ +E Q+ L LK +++ + + V Q+ D++ TLE
Sbjct: 691 VEAEELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKE---TLENMMQ 747
Query: 74 KLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSE-DLE 132
+ E E H++ +I+ + A++S +L++ ++L E + A +SSL ++ +++
Sbjct: 748 RHEEEAHEKGKILSEQKAMINAMDSK----IRSLEQRIVELSEANKLAANSSLFTQRNMK 803
Query: 133 ARNETLSNTLVE---LSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEH 189
A+ E +S + L Q G+L+A+ + L ++ +E ++H D S K ++LE
Sbjct: 804 AQEEMISELRQQKFYLETQAGKLEAQNRKL--------EEQLEKISH-QDHSDKNRLLE- 853
Query: 190 ALRDAKMAETCIVKEKQDYKQKLK-----------------------ALKIEVNKLKEDL 226
+ ++ E + E+Q + K + AL+ ++ + K +L
Sbjct: 854 --LETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTEL 911
Query: 227 NEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLN-IAKSKQERTNSELHNL 285
E T E E+ + + + E D L + +E LN + + E N +
Sbjct: 912 EETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLS 971
Query: 286 RQI---------YVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLEN 336
+Q+ V+ +S++ L + + + ME K + + + DLE
Sbjct: 972 KQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVMDLE- 1030
Query: 337 NHPKVDIKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDEC--KEKKQQIDT 385
N + L K++++EA + D+ S EC +E ++ +DT
Sbjct: 1031 ---------ALNDELLEKERQWEAW--RSVLGDEKSQFECRVRELQRMLDT 1070
Score = 49.7 bits (117), Expect = 9e-06
Identities = 80/345 (23%), Positives = 149/345 (43%), Gaps = 32/345 (9%)
Query: 73 SKLEGELHKRTEIIRSLTK--KVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSED 130
SK G L + ++ L K ++E + LQ +Q + +M Q+ T +
Sbjct: 422 SKALGILGRSESVVSGLDSPAKTSSMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSE 481
Query: 131 LEARNETLSNTLVELSAQVGQLQAREQALTTMI----KLKDKDIIEAVNHIADCSGKFKM 186
+EA LS VEL A Q EQ L T I LK + + +A ++ K
Sbjct: 482 VEA---VLSQKEVELKASETQRSLLEQDLATYITECSSLK-RSLEQARMEVSQEDDKALQ 537
Query: 187 LEHALRDA--KMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLK 244
L H +R+ K+ E +KE Q+Y+ +++ +++ +N+L+EDL + +R ++ +
Sbjct: 538 LLHDIREQSRKLQE---IKE-QEYQAQVEEMRLMMNQLEEDL-----VSARRRSDLYESE 588
Query: 245 QEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVE 304
+S L E F + + + +LL AK + + E L +I +QQ +Q L +E
Sbjct: 589 LRESRLAAE-EFKRKATECQHKLLK-AKDQGKPEVGEYAKLEKINAEQQLKIQELQEKLE 646
Query: 305 NSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQ 364
+ + ++ + + L L+N RE + + + K L +
Sbjct: 647 KAVKASTEATELLQNIRQAKERAERELEKLQN--------REDSSEGIRKKLVEAEELEE 698
Query: 365 QNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSIFTKDLVEKHNL 409
++R + S + +Q + + EK + L + KDL +K L
Sbjct: 699 KHREAQVSAQHLEVHLKQKEQHYEEK-IKVLDNQIKKDLADKETL 742
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 67.0 bits (162), Expect = 5e-11
Identities = 78/371 (21%), Positives = 162/371 (43%), Gaps = 41/371 (11%)
Query: 25 KQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGELHKRTE 84
+ +KE Q +LK +KE+ ++ Q DR ++ LE K+E L+
Sbjct: 73 ESKKESQKNDKDLKILEKEIRVLLQERGAQ------DR-RIQDLETELEKMEARLNAALR 125
Query: 85 IIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNETLSNTLVE 144
SL+ LE +E + + + E + L E ++ RN+
Sbjct: 126 EKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKR------- 178
Query: 145 LSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMAETCIVKE 204
++ + A+++ + +++ + + E+ IA GK +E D K +ET ++
Sbjct: 179 -ETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEK-SET---EK 233
Query: 205 KQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVER---- 260
+Y +++ +V K K D+ + E+ +EI+ LKQ L + ++ ++
Sbjct: 234 LLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQS---LEENIVILSKQVEDL 290
Query: 261 -------EKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQELIQMY 313
EK K++ +N + E N+E+ NL+Q ++ +Q + + L Q+ +Q+
Sbjct: 291 NVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKL------QQKELQI- 343
Query: 314 DSKMEESKALDSSRDMCLSDLENNHPK-VDIKREKNQKSLFKDQKFEAMLVQQNRSDKSS 372
DS +++ K L SS L + K ++ E+ +++L + K + Q R K
Sbjct: 344 DSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQL 403
Query: 373 CDECKEKKQQI 383
+E K + +++
Sbjct: 404 EEEAKSRAEEL 414
Score = 50.1 bits (118), Expect = 7e-06
Identities = 81/370 (21%), Positives = 156/370 (42%), Gaps = 44/370 (11%)
Query: 17 EVEISTIEKQRKEL-----QLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEER 71
E++I ++ +Q KEL Q L ++ KE N +Q L ++ +QK E
Sbjct: 340 ELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERL 399
Query: 72 CSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDL 131
+LE E R E ++ L +K+K E+ +L++ + T ++LL L
Sbjct: 400 VKQLEEEAKSRAEELKLLEEKLKGKEA--------------ELEKSSAAHTQATLL---L 442
Query: 132 EARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHAL 191
+ + +++ +L +++AQ +A + +KL++ + E A + ++H +
Sbjct: 443 QEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKA---AKAGKNAEDVQHQI 499
Query: 192 RDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLH 251
+ + V+ D + K + E+ ++ +K T+ Q LKQ++
Sbjct: 500 LATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQ------LKQQEEDFR 553
Query: 252 DELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQS-DLQFLNFNVENSQELI 310
+L + E RK E N E N ++Y K + LQ F VE Q L+
Sbjct: 554 KQL---EDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAFEVE-KQALL 609
Query: 311 QMYDSKMEESKALDSSRDMCLSDLENNHPKVDIK---REKNQKSLFKDQ--KFEAMLVQQ 365
+ + E+ L+ RD L + + K IK + K++ S K + K L ++
Sbjct: 610 NEHGAAQEQ---LNKIRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRCQLAKK 666
Query: 366 NRSDKSSCDE 375
+S+ +E
Sbjct: 667 KQSETKLQEE 676
Score = 38.5 bits (88), Expect = 0.021
Identities = 57/236 (24%), Positives = 107/236 (45%), Gaps = 39/236 (16%)
Query: 28 KELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQK----VLTLEERCSKLEGELHKRT 83
++L+L L+++ + Q Q+L+ E Q+ +L L+ + + E E+
Sbjct: 472 EDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIK--- 528
Query: 84 EIIRSLTKKVKALESNQMECQTALQKTQLQLQE--MAQKATHSSLLSEDLEARN---ETL 138
EI S +K+ L+ NQ++ Q + QL+ +E A+K ++ L+E++ E L
Sbjct: 529 EITVSFLQKITDLQ-NQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEEL 587
Query: 139 SNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMAE 198
N Q+ + +QAL + E +N I D K +L H
Sbjct: 588 YNKTKPFQLQLDAFEVEKQALLN----EHGAAQEQLNKIRDSYAK--LLGH--------- 632
Query: 199 TCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDEL 254
Q+ KQK+K V KLK++ ++ +E ++ R ++ + KQ ++ L +EL
Sbjct: 633 -------QNLKQKIK----HVVKLKDENSQLKSEVSKLRCQLAKKKQSETKLQEEL 677
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 66.6 bits (161), Expect = 7e-11
Identities = 90/421 (21%), Positives = 174/421 (41%), Gaps = 68/421 (16%)
Query: 23 IEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKV----LTLEERCSKLEGE 78
+E++ + Q L E K + + ++ ++QL E RQK+ +T E + KLE E
Sbjct: 924 VEEEEERCQHLQAEKKKMQQNIQEL----EEQLEEEESARQKLQLEKVTTEAKLKKLEEE 979
Query: 79 LHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQ-KATHSSLLSE-------- 129
+ L K+ K LE E T L + + + + +A+ K H +++++
Sbjct: 980 QIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRRE 1039
Query: 130 -----DLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDI------IE------ 172
+LE L +LS Q+ +LQA+ L + K++++ +E
Sbjct: 1040 EKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQK 1099
Query: 173 --AVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKI------------- 217
A+ I + + L+ L + + K+K+D ++L+ALK
Sbjct: 1100 NMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159
Query: 218 --------EVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLN 269
EVN LK+ L E+ + Q +E ++Q+ S +EL +E+ KR L
Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQE---MRQKHSQAVEELAEQLEQTKRVKANLE 1216
Query: 270 IAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDM 329
AK E EL N ++ ++ + D + VE + +Q+ ++ E + + +
Sbjct: 1217 KAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVT 1276
Query: 330 CLSDLENNHPKVDIKREKNQKSLFKD--------QKFEAMLVQQNRSDKSSCDECKEKKQ 381
L +N + + + L KD Q + +L ++NR S + K+ +
Sbjct: 1277 KLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVED 1336
Query: 382 Q 382
+
Sbjct: 1337 E 1337
Score = 60.1 bits (144), Expect = 7e-09
Identities = 91/443 (20%), Positives = 178/443 (40%), Gaps = 68/443 (15%)
Query: 17 EVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLE 76
E + +EK R++L+ +L D+ EL +A + QL EE+ Q L +++E
Sbjct: 1040 EKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAAL------ARVE 1093
Query: 77 GELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNE 136
E ++ + KK++ LES E Q L+ + + A+K L E+LEA
Sbjct: 1094 EEAAQKNMAL----KKIRELESQISELQEDLESERAS-RNKAEKQKRD--LGEELEALKT 1146
Query: 137 TLSNTLVELSAQVGQLQAREQALTTMIKLKDKDI--------------IEAVNHIADCSG 182
L +TL +AQ REQ + + K +++ +AV +A+
Sbjct: 1147 ELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLE 1206
Query: 183 KFKMLEHALRDAKMA-----------ETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTT 231
+ K ++ L AK +++ K D + K K ++ ++ +L+ NE
Sbjct: 1207 QTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGER 1266
Query: 232 ENNEQREEIIRLKQE-------------------------KSCLHDELLFTVEREKRKDE 266
E +++ +L+ E +S L D E ++K
Sbjct: 1267 VRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLS 1326
Query: 267 LLNIAKSKQERTNSELHNL-RQIYVKQQSDLQFLNFNVENSQELIQMYDSK--MEESKAL 323
L K ++ NS L + K + Q + + + +M DS +E ++ +
Sbjct: 1327 LSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEV 1386
Query: 324 DSSRDMCLSDLENNHPKVDIKREKNQKSLFK-DQKFEAMLVQQNRSDKSSCDECKEKKQQ 382
L L H + +K +K+ + Q+ + +LV + +S+C+ ++K+++
Sbjct: 1387 KRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACN-LEKKQKK 1445
Query: 383 IDTVFGEKSVITLSSIFTKDLVE 405
D + E+ I+ +D E
Sbjct: 1446 FDQLLAEEKTISAKYAEERDRAE 1468
Score = 56.6 bits (135), Expect = 7e-08
Identities = 78/397 (19%), Positives = 167/397 (42%), Gaps = 58/397 (14%)
Query: 8 LAGRQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLL----------- 56
++ + ++G V +EK ++ L+ + E+K + +EL D + + L
Sbjct: 1510 MSSKDDVGKSVH--ELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKA 1567
Query: 57 ------------SWEEDRQKVLTLEERCSKLEGELHKRTEII---RSLTKKVKALES--- 98
S E+ +Q V + E ++LE E +R+ + + L +K LE+
Sbjct: 1568 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 1627
Query: 99 ----NQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQA 154
N+ E L+K Q Q+++ ++ + E++ A+ + L + A++ QLQ
Sbjct: 1628 SANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQE 1687
Query: 155 REQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQ---- 210
A + ++ E + IA+ SGK + AL + + E I + +++ ++
Sbjct: 1688 ELAAAERAKRQAQQERDELADEIANSSGKGAL---ALEEKRRLEARIAQLEEELEEEQGN 1744
Query: 211 ------KLKALKIEVNKLKEDLN---EKTTENNEQREEIIRLKQEKSCLHDELLFTVERE 261
+LK ++++++ DLN +N R+++ R +E E+ TV+ +
Sbjct: 1745 TELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSK 1804
Query: 262 KRKDELLNIAKSKQ--ERTNSELHNLRQIYVKQ----QSDLQFLNFNVENSQELIQMYDS 315
+ AK Q E+ ++E RQ KQ + L+ + V++ + + Y
Sbjct: 1805 YKASITALEAKIAQLEEQLDNETKE-RQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKD 1863
Query: 316 KMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSL 352
+ +++ L + E + + R K Q+ L
Sbjct: 1864 QADKASTRLKQLKRQLEEAEEEAQRANASRRKLQREL 1900
Score = 49.3 bits (116), Expect = 1e-05
Identities = 83/389 (21%), Positives = 164/389 (42%), Gaps = 42/389 (10%)
Query: 23 IEKQRKELQLLIGEL-KDRDKEL---NDMVAVH--QQQLLSWEEDRQKVLTLE-ERCSKL 75
+ +Q +E+ EL K R+K+L N + + Q QL++ + Q+ L E E C++
Sbjct: 840 VSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEA 899
Query: 76 EGELHKRT--------EIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLL 127
E EL R EI L +V+ E Q +K Q +QE+ ++
Sbjct: 900 E-ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESA 958
Query: 128 SEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKML 187
+ L+ T L +L + L+ + L KL + I E ++ + K K L
Sbjct: 959 RQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSL 1018
Query: 188 -----EHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIR 242
+H + E +EKQ +Q+L+ + KL+ D + + + E + +I
Sbjct: 1019 AKLKNKHEAMITDLEERLRREEKQ--RQELEKTR---RKLEGDSTDLSDQIAELQAQIAE 1073
Query: 243 LKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFN 302
LK + + +EL + R + + N+A K S++ L++ +++
Sbjct: 1074 LKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQ 1133
Query: 303 VENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKN----QKSLFKDQK- 357
+ E ++ +++E++ LDS+ ++ KRE+ +K+L ++ K
Sbjct: 1134 KRDLGEELEALKTELEDT--LDSTA---------AQQELRSKREQEVNILKKTLEEEAKT 1182
Query: 358 FEAMLVQQNRSDKSSCDECKEKKQQIDTV 386
EA + + + + +E E+ +Q V
Sbjct: 1183 HEAQIQEMRQKHSQAVEELAEQLEQTKRV 1211
>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
sapiens]
Length = 1133
Score = 66.6 bits (161), Expect = 7e-11
Identities = 87/428 (20%), Positives = 172/428 (40%), Gaps = 63/428 (14%)
Query: 23 IEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQK-----------VLTLEER 71
+EK ++ + ++G+L +K +Q +L EE+++K + LE+
Sbjct: 147 VEKHKESYRRILGQLLVAEKS-------RRQTILELEEEKRKHKEYMEKSDEFICLLEQE 199
Query: 72 CSKL--------------EGELHKRTEIIRSLTKKVKAL------ESNQMECQTALQKTQ 111
C +L E E KR ++ K+K+ E ++ Q LQ+ +
Sbjct: 200 CERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQLTLQRQK 259
Query: 112 LQLQEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDI- 170
+Q K TH+ L + + E T +E Q + + T M KL ++D
Sbjct: 260 IQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQ 319
Query: 171 -IEAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLK-------ALKIEVNKL 222
+ +A S + LE R + AE +E QD K+K+ + EV
Sbjct: 320 NRQLQQKLAALSRQIDELEETNRSLRKAE----EELQDIKEKISKGEYGNAGIMAEV--- 372
Query: 223 KEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSEL 282
E+L ++ + + EE+I+++++ L+ L ERE + + + K + L
Sbjct: 373 -EELRKRVLDMEGKDEELIKMEEQCRDLNKRL----ERETLQSKDFKLEVEKLSKRIMAL 427
Query: 283 HNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNH--PK 340
L + K + + L N+E + + ++E K + S LE K
Sbjct: 428 EKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELEAIESRLEKTEFTLK 487
Query: 341 VDIKREKNQKSLFKDQKFEAMLVQQNRSDK--SSCDECKEKKQQIDTVFGEKSVITLSSI 398
D+ + K +F D++ + DK ++ + + ++ ++ TV + T ++
Sbjct: 488 EDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRAL 547
Query: 399 FTKDLVEK 406
+K VE+
Sbjct: 548 KSKTDVEE 555
Score = 62.0 bits (149), Expect = 2e-09
Identities = 72/337 (21%), Positives = 144/337 (42%), Gaps = 39/337 (11%)
Query: 15 GSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSK 74
G + E+ +E+Q ++L + + K+ V +++++ E+ ++ C
Sbjct: 384 GKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYS 443
Query: 75 LEGELHKRTEIIRSLTKKVKALESNQMECQ---TALQKTQLQLQE-MAQKATHSSLLSED 130
L+ L K + L++++++L+ E + + L+KT+ L+E + + T + + ++
Sbjct: 444 LKCNLEKERMTTKQLSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDE 503
Query: 131 LEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHA 190
+ +E L T +L A QLQ + +TT+ + ++ A+ D K
Sbjct: 504 RKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKM------ 557
Query: 191 LRDAKMAETCIVKEKQDYKQKLKA-------LKIEVNKLKEDLNE---------KTTENN 234
+ KE+ D K KLKA L VN LK L K N
Sbjct: 558 --------YSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQ 609
Query: 235 EQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQS 294
+ + L QE + + EL VER K K + + + +T E L + Y ++
Sbjct: 610 DSGKSTTALHQENNKI-KELSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRYANERD 668
Query: 295 DLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCL 331
QFL+ +E+ ++M +K + ++ ++S + L
Sbjct: 669 KAQFLSKELEH----VKMELAKYKLAEKTETSHEQWL 701
>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
sapiens]
Length = 1135
Score = 66.6 bits (161), Expect = 7e-11
Identities = 87/428 (20%), Positives = 172/428 (40%), Gaps = 63/428 (14%)
Query: 23 IEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQK-----------VLTLEER 71
+EK ++ + ++G+L +K +Q +L EE+++K + LE+
Sbjct: 147 VEKHKESYRRILGQLLVAEKS-------RRQTILELEEEKRKHKEYMEKSDEFICLLEQE 199
Query: 72 CSKL--------------EGELHKRTEIIRSLTKKVKAL------ESNQMECQTALQKTQ 111
C +L E E KR ++ K+K+ E ++ Q LQ+ +
Sbjct: 200 CERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQLTLQRQK 259
Query: 112 LQLQEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDI- 170
+Q K TH+ L + + E T +E Q + + T M KL ++D
Sbjct: 260 IQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQ 319
Query: 171 -IEAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLK-------ALKIEVNKL 222
+ +A S + LE R + AE +E QD K+K+ + EV
Sbjct: 320 NRQLQQKLAALSRQIDELEETNRSLRKAE----EELQDIKEKISKGEYGNAGIMAEV--- 372
Query: 223 KEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSEL 282
E+L ++ + + EE+I+++++ L+ L ERE + + + K + L
Sbjct: 373 -EELRKRVLDMEGKDEELIKMEEQCRDLNKRL----ERETLQSKDFKLEVEKLSKRIMAL 427
Query: 283 HNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNH--PK 340
L + K + + L N+E + + ++E K + S LE K
Sbjct: 428 EKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELEAIESRLEKTEFTLK 487
Query: 341 VDIKREKNQKSLFKDQKFEAMLVQQNRSDK--SSCDECKEKKQQIDTVFGEKSVITLSSI 398
D+ + K +F D++ + DK ++ + + ++ ++ TV + T ++
Sbjct: 488 EDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRAL 547
Query: 399 FTKDLVEK 406
+K VE+
Sbjct: 548 KSKTDVEE 555
Score = 62.0 bits (149), Expect = 2e-09
Identities = 72/337 (21%), Positives = 144/337 (42%), Gaps = 39/337 (11%)
Query: 15 GSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSK 74
G + E+ +E+Q ++L + + K+ V +++++ E+ ++ C
Sbjct: 384 GKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYS 443
Query: 75 LEGELHKRTEIIRSLTKKVKALESNQMECQ---TALQKTQLQLQE-MAQKATHSSLLSED 130
L+ L K + L++++++L+ E + + L+KT+ L+E + + T + + ++
Sbjct: 444 LKCNLEKERMTTKQLSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDE 503
Query: 131 LEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHA 190
+ +E L T +L A QLQ + +TT+ + ++ A+ D K
Sbjct: 504 RKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKM------ 557
Query: 191 LRDAKMAETCIVKEKQDYKQKLKA-------LKIEVNKLKEDLNE---------KTTENN 234
+ KE+ D K KLKA L VN LK L K N
Sbjct: 558 --------YSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQ 609
Query: 235 EQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQS 294
+ + L QE + + EL VER K K + + + +T E L + Y ++
Sbjct: 610 DSGKSTTALHQENNKI-KELSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRYANERD 668
Query: 295 DLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCL 331
QFL+ +E+ ++M +K + ++ ++S + L
Sbjct: 669 KAQFLSKELEH----VKMELAKYKLAEKTETSHEQWL 701
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 66.6 bits (161), Expect = 7e-11
Identities = 71/384 (18%), Positives = 168/384 (43%), Gaps = 19/384 (4%)
Query: 14 IGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCS 73
+ E E+ I Q + + + ++K K+L D+ A + Q +E + LE+
Sbjct: 1517 VSLEAELQDISSQESKDEASLAKVK---KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKL 1573
Query: 74 KLEGELHK-RTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLE 132
+LE E+ + R + + + + +E + CQ L++ ++QL+E + +LE
Sbjct: 1574 RLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELE 1633
Query: 133 ARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDI-IEAVNHIADCSGKFKMLEHAL 191
+ TLS+ + + + + R+ T L D + ++ + + A + L++ L
Sbjct: 1634 GKLATLSDQVNRRDFE-SEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQL 1692
Query: 192 RDAKMAETCIVKEKQDYKQKLKALKIEVNK-------LKEDLNEKTTENNEQREEIIRLK 244
+++ VK ++ + +++ L ++++ L+E L+ E NE + + +
Sbjct: 1693 EESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQ 1752
Query: 245 QEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFN-- 302
++ + L + V + R +N +++ E N E L++ QS ++FL +
Sbjct: 1753 EDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV 1812
Query: 303 ----VENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKF 358
V + I+ ++++E + + S L+ N K+ +R++ + ++++
Sbjct: 1813 DKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQ 1872
Query: 359 EAMLVQQNRSDKSSCDECKEKKQQ 382
L +Q R K E K+ +
Sbjct: 1873 NKRLQRQLRDTKEEMGELARKEAE 1896
Score = 54.7 bits (130), Expect = 3e-07
Identities = 82/408 (20%), Positives = 173/408 (42%), Gaps = 38/408 (9%)
Query: 17 EVEISTIEKQRKELQLLIGELK-----DRDKELNDMVAVHQQQLLSWEEDRQKVLTLEER 71
+ + ++KQ + +++ + E + + + E++D A + +L R+ T +
Sbjct: 1330 QTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRL 1389
Query: 72 CSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDL 131
+ E +L + R L +++ L+++ E Q ALQ+ + + Q + + + L E
Sbjct: 1390 QQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQ 1449
Query: 132 EARNETLSNTLVELSAQVGQL--QAREQALTTMIKLKDKDII------------EAVNHI 177
+ RN L +++ Q +A+ + L ++KD++ E I
Sbjct: 1450 QVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDI 1509
Query: 178 ADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQR 237
A + K LE L+D E+ K++L+ L+ +V +E+L+E+
Sbjct: 1510 AGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLE 1569
Query: 238 EEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDL- 296
+ +RL+ E + + E E R +E+ +S Q++ L + Y +Q L
Sbjct: 1570 QAKLRLEMEMERMRQ--THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLR 1627
Query: 297 --QFLNFNVENSQELIQMYDSKMEE--------SKALDSSRDMCLSDLENNHP-KVDIKR 345
+ L + + + D + E+ +KAL + + L L+N+ P K +I +
Sbjct: 1628 EKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQ 1687
Query: 346 EKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVI 393
KNQ ++ +F + R K+ E ++ QID + K+ +
Sbjct: 1688 LKNQ---LEESEFTCAAAVKAR--KAMEVEIEDLHLQIDDIAKAKTAL 1730
Score = 39.7 bits (91), Expect = 0.009
Identities = 40/162 (24%), Positives = 74/162 (45%), Gaps = 15/162 (9%)
Query: 8 LAGRQNIGSEVEISTIEKQ--RKELQLLIGELKDRDKELNDMVAVHQQQL------LSWE 59
LA ++ +++E + EKQ +++LQ L +++ ++ + D V +Q+ E
Sbjct: 1773 LAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLE 1832
Query: 60 EDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQ 119
+R +V LE S+L+ + K TE + Q L+ T+ ++ E+A+
Sbjct: 1833 FERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELAR 1892
Query: 120 KATHSSLLS-------EDLEARNETLSNTLVELSAQVGQLQA 154
K +S E LEA N++L L ++G LQA
Sbjct: 1893 KEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQA 1934
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 66.6 bits (161), Expect = 7e-11
Identities = 71/384 (18%), Positives = 168/384 (43%), Gaps = 19/384 (4%)
Query: 14 IGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCS 73
+ E E+ I Q + + + ++K K+L D+ A + Q +E + LE+
Sbjct: 1517 VSLEAELQDISSQESKDEASLAKVK---KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKL 1573
Query: 74 KLEGELHK-RTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLE 132
+LE E+ + R + + + + +E + CQ L++ ++QL+E + +LE
Sbjct: 1574 RLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELE 1633
Query: 133 ARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDI-IEAVNHIADCSGKFKMLEHAL 191
+ TLS+ + + + + R+ T L D + ++ + + A + L++ L
Sbjct: 1634 GKLATLSDQVNRRDFE-SEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQL 1692
Query: 192 RDAKMAETCIVKEKQDYKQKLKALKIEVNK-------LKEDLNEKTTENNEQREEIIRLK 244
+++ VK ++ + +++ L ++++ L+E L+ E NE + + +
Sbjct: 1693 EESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQ 1752
Query: 245 QEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFN-- 302
++ + L + V + R +N +++ E N E L++ QS ++FL +
Sbjct: 1753 EDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV 1812
Query: 303 ----VENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKF 358
V + I+ ++++E + + S L+ N K+ +R++ + ++++
Sbjct: 1813 DKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQ 1872
Query: 359 EAMLVQQNRSDKSSCDECKEKKQQ 382
L +Q R K E K+ +
Sbjct: 1873 NKRLQRQLRDTKEEMGELARKEAE 1896
Score = 54.7 bits (130), Expect = 3e-07
Identities = 82/408 (20%), Positives = 173/408 (42%), Gaps = 38/408 (9%)
Query: 17 EVEISTIEKQRKELQLLIGELK-----DRDKELNDMVAVHQQQLLSWEEDRQKVLTLEER 71
+ + ++KQ + +++ + E + + + E++D A + +L R+ T +
Sbjct: 1330 QTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRL 1389
Query: 72 CSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDL 131
+ E +L + R L +++ L+++ E Q ALQ+ + + Q + + + L E
Sbjct: 1390 QQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQ 1449
Query: 132 EARNETLSNTLVELSAQVGQL--QAREQALTTMIKLKDKDII------------EAVNHI 177
+ RN L +++ Q +A+ + L ++KD++ E I
Sbjct: 1450 QVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDI 1509
Query: 178 ADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQR 237
A + K LE L+D E+ K++L+ L+ +V +E+L+E+
Sbjct: 1510 AGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLE 1569
Query: 238 EEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDL- 296
+ +RL+ E + + E E R +E+ +S Q++ L + Y +Q L
Sbjct: 1570 QAKLRLEMEMERMRQ--THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLR 1627
Query: 297 --QFLNFNVENSQELIQMYDSKMEE--------SKALDSSRDMCLSDLENNHP-KVDIKR 345
+ L + + + D + E+ +KAL + + L L+N+ P K +I +
Sbjct: 1628 EKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQ 1687
Query: 346 EKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVI 393
KNQ ++ +F + R K+ E ++ QID + K+ +
Sbjct: 1688 LKNQ---LEESEFTCAAAVKAR--KAMEVEIEDLHLQIDDIAKAKTAL 1730
Score = 40.0 bits (92), Expect = 0.007
Identities = 44/199 (22%), Positives = 90/199 (45%), Gaps = 20/199 (10%)
Query: 8 LAGRQNIGSEVEISTIEKQ--RKELQLLIGELKDRDKELNDMVAVHQQQL------LSWE 59
LA ++ +++E + EKQ +++LQ L +++ ++ + D V +Q+ E
Sbjct: 1773 LAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLE 1832
Query: 60 EDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQ 119
+R +V LE S+L+ + K TE + Q L+ T+ ++ E+A+
Sbjct: 1833 FERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELAR 1892
Query: 120 KATHSSLLS-------EDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIE 172
K +S E LEA N++L L ++G LQA + +++ + +
Sbjct: 1893 KEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIED-----EMESDENED 1947
Query: 173 AVNHIADCSGKFKMLEHAL 191
+N + D K++ ++ L
Sbjct: 1948 LINSLQDMVTKYQKRKNKL 1966
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 65.9 bits (159), Expect = 1e-10
Identities = 79/409 (19%), Positives = 179/409 (43%), Gaps = 34/409 (8%)
Query: 15 GSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSK 74
G + EI+ E Q +EL+ + E + KEL V Q+++ E+ + + C++
Sbjct: 392 GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQ 451
Query: 75 LEGELHKRTEIIRSLTKKVKALES--NQMEC-QTALQKTQLQLQEMAQKATHSSLLSEDL 131
L L K + + L +++ ++S ++EC ++ L+K +L L++ K +++ D
Sbjct: 452 LHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVD- 510
Query: 132 EARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHAL 191
E +N + ++ Q + + L K++ +++ + + S K L+ +
Sbjct: 511 ERKN---------MMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEM 561
Query: 192 RDAKMAETCIVKEKQDYKQKLKALKIEVNKL--KEDLNEKTTENNEQREEII-----RLK 244
+ + +E+ + KLK+ + + ++L DL +K + E+ E I R
Sbjct: 562 EEKVYN---LTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKG 618
Query: 245 QEKSCLHD----ELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLN 300
E +C D EL +ER K++ + L + + +T E L Q + +Q FL+
Sbjct: 619 SELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLS 678
Query: 301 FNVENSQELIQMYDSKMEESKALDSSRDM----CLSDLENNHPKVDIK--REKNQKSLFK 354
+E + I + +E+ + + ++ L + ++ K +++ +EK + + K
Sbjct: 679 QQLEEIKHQIAK-NKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHELMNK 737
Query: 355 DQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSIFTKDL 403
+ + + V + + +E + K V + LS +++ L
Sbjct: 738 EDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELELSKRYSRAL 786
Score = 60.8 bits (146), Expect = 4e-09
Identities = 93/421 (22%), Positives = 183/421 (43%), Gaps = 71/421 (16%)
Query: 17 EVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLE------- 69
++ I + Q +++Q L +L++ +++L + + + EDRQK+L LE
Sbjct: 255 QMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSK-------EDRQKLLKLEVDFEHKA 307
Query: 70 --------ERCSKLEG-ELHKRTEIIR--SLTKKVKALESNQMECQTALQKTQLQLQEMA 118
E +KL E H R ++ LT++++ LE E LQK + +LQE+
Sbjct: 308 SRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELE----ETNKNLQKAEEELQELR 363
Query: 119 QKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIA 178
K + L A E L ++E+ + ++ E + K + E +H
Sbjct: 364 DKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCREL----RKKLQEEEHHSK 419
Query: 179 DCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNE--------KT 230
+ + + L+ + + + E K K + Q L+ E N K+ LNE K
Sbjct: 420 ELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKE 479
Query: 231 TENNEQR---------EEIIRLKQEKSCLHDE---LLFTVEREKRKDELLN----IAKSK 274
E +E R +++ +LK L DE ++ +++E+RK + LN + + K
Sbjct: 480 LECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGK 539
Query: 275 QERTNSELHNLRQIYVKQQSDLQFLNFNVENSQ-ELIQMYDSKMEESKALDSSRDMCLSD 333
+L + +K +S+++ +N+ + ELI S+ E+S L S D+
Sbjct: 540 VMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKR 599
Query: 334 LEN-NHPKVDIKREKNQK----SLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFG 388
L+ + +I R +++K + +D K + + ++ R K++ QQ++ V G
Sbjct: 600 LDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIER--------LKKRLQQLEVVEG 651
Query: 389 E 389
+
Sbjct: 652 D 652
Score = 32.7 bits (73), Expect = 1.1
Identities = 85/489 (17%), Positives = 193/489 (39%), Gaps = 93/489 (19%)
Query: 9 AGRQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTL 68
AG +++ + + ++++ + G +K K + ++ L +ED ++L++
Sbjct: 27 AGEKSLSEDAKKKKKSNRKEDDVMASGTVKRHLKTSGECERKTKKSLELSKEDLIQLLSI 86
Query: 69 EERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLS 128
+EGEL R ++I L K + + +E + + L+ + + A +L+
Sbjct: 87 ------MEGELQAREDVIHML--KTEKTKPEVLEAHYGSAEPEKVLRVLHRDA----ILA 134
Query: 129 EDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLE 188
++ + + EL + E+ T ++ ++ ++ H +
Sbjct: 135 QEKSIGEDVYEKPISELD------RLEEKQKETYRRMLEQLLLAEKCH--------RRTV 180
Query: 189 HALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLN----EKTTEN----NEQREEI 240
+ L + K T + + D+ L+ + + KL E K EN N+ R+E+
Sbjct: 181 YELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDEL 240
Query: 241 IRLKQEKSCLHDELLFTVE----------------REKRKDELLNIAKSKQER------- 277
++LK L DE +E RE+ + +KSK++R
Sbjct: 241 VKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLE 300
Query: 278 ---------------------TNSELHNLRQIYVK------QQSDLQFLNFNVENSQELI 310
N E HN RQ+ +K + +L+ N N++ ++E +
Sbjct: 301 VDFEHKASRFSQEHEEMNAKLANQESHN-RQLRLKLVGLTQRIEELEETNKNLQKAEEEL 359
Query: 311 QMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRSDK 370
Q K+ + + +SS ++++EN +V ++ E + + K + L ++ + ++
Sbjct: 360 QELRDKIAKGECGNSS---LMAEVENLRKRV-LEMEGKDEEITKTESQCRELRKKLQEEE 415
Query: 371 SSCDECKEKKQQIDTVFGEKSVITLSSIFTKDLVEKHNLPWSLGGKTQIEPE--NKITLC 428
E + + +++ E + L F+K E L +L + + + N++ +
Sbjct: 416 HHSKELRLEVEKLQKRMSE--LEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVV 473
Query: 429 KIHTKSPKC 437
K K +C
Sbjct: 474 KSRVKELEC 482
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 65.1 bits (157), Expect = 2e-10
Identities = 83/400 (20%), Positives = 166/400 (41%), Gaps = 36/400 (9%)
Query: 11 RQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEE 70
R+N+ +++E EK +E QL+ K ++K ND+ +++ D LT
Sbjct: 853 RENL-ADMEAKFREKDEREEQLI----KAKEKLENDIA-----EIMKMSGDNSSQLT--- 899
Query: 71 RCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHS-SLLSE 129
K+ EL + + L K+ N Q +++ ++ ++ Q+A +
Sbjct: 900 ---KMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKK 956
Query: 130 DLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNH-IADCSGKFKMLE 188
+LE + L + Q +L+AR + T+ K K ++I++ + + D K K
Sbjct: 957 ELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAR 1016
Query: 189 HALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTEN----NEQREEIIRLK 244
++ + + KQ K K + ++ E + ++ TE + ++ +L+
Sbjct: 1017 E--ENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQ 1074
Query: 245 QEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFL-NFNV 303
E L + L VE + ELL + K E E+ L+Q ++ L L NV
Sbjct: 1075 NELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENV 1134
Query: 304 ENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLV 363
+ ++EL + D K L+ R + + L ++ +K + KD E +
Sbjct: 1135 KLAEELGRSRDEVTSHQK-LEEERSVLNNQL--------LEMKKRESKFIKDADEEKASL 1185
Query: 364 QQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSIFTKDL 403
Q++ S S+ EK +++ + E +V+ + K L
Sbjct: 1186 QKSISITSAL--LTEKDAELEKLRNEVTVLRGENASAKSL 1223
Score = 61.6 bits (148), Expect = 2e-09
Identities = 68/375 (18%), Positives = 161/375 (42%), Gaps = 19/375 (5%)
Query: 19 EISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVL----TLEERCSK 74
++ EKQ K L++ + + + + +L + +E+ +V TLE+
Sbjct: 750 QLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQI 809
Query: 75 LEGELHKRTE----IIRSLTKKVKALESNQME---CQTALQKTQLQLQEMAQKATHSSLL 127
L+ + + +E + RS+ + V L + + + L+K + L +M K
Sbjct: 810 LKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDER 869
Query: 128 SEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKML 187
E L E L N + E+ G ++ + ++LK++D+ E + + L
Sbjct: 870 EEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFL 929
Query: 188 EHALRDAKM-AETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQE 246
+ ++ D + AE + + ++++ K L+ +++ L++ + + E + R E
Sbjct: 930 QKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSE 989
Query: 247 KSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENS 306
H+E+L +++ E + K +E + L L ++ ++Q+D E++
Sbjct: 990 TKTKHEEILQNLQKTLLDTE--DKLKGAREENSGLLQELEEL--RKQADKAKAAQTAEDA 1045
Query: 307 QELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQN 366
++++ + E+ A + L+N ++D +E N K++ + K + +L +N
Sbjct: 1046 MQIMEQMTKEKTETLASLEDTKQTNAKLQN---ELDTLKENNLKNVEELNKSKELLTVEN 1102
Query: 367 RSDKSSCDECKEKKQ 381
+ + E + KQ
Sbjct: 1103 QKMEEFRKEIETLKQ 1117
Score = 56.6 bits (135), Expect = 7e-08
Identities = 83/407 (20%), Positives = 169/407 (41%), Gaps = 58/407 (14%)
Query: 19 EISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGE 78
++ E + KEL++L + ++ K +++ + QL + EE + L + S+ + E
Sbjct: 688 KLQEAEIKVKELEVLQAKCNEQTKVIDNFTS----QLKATEEKLLDLDALRKASSEGKSE 743
Query: 79 LHKRTEIIRSLTKKVKALE-------SNQMECQTALQKTQLQLQEMAQKATHSSLLSEDL 131
+ K + + + K++K LE S LQ +L+L + + + S + E L
Sbjct: 744 MKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETL 803
Query: 132 EARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDK-------DIIEAVNHIADCSGKF 184
E + L E S + +Q Q + K++ D+ + ++AD KF
Sbjct: 804 EKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKF 863
Query: 185 KMLEHALRDAKMAETCIVKEKQDYKQKLKAL-------KIEVNKLKEDLNEKTTENNEQR 237
R+ E ++K K+ + + + ++ K+ ++L K + E +
Sbjct: 864 -------REKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQ 916
Query: 238 EEIIRLKQEKSCLHDELL-FTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDL 296
++ + + S L + TV+ E+ + E A K E EL ++ SDL
Sbjct: 917 LKLTKANENASFLQKSIEDMTVKAEQSQQE----AAKKHEEEKKELE-------RKLSDL 965
Query: 297 Q-FLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLE----NNHPKVDIKREKNQKS 351
+ + + QEL Y+ E+K + + L +L+ + K+ RE+N
Sbjct: 966 EKKMETSHNQCQELKARYERATSETK---TKHEEILQNLQKTLLDTEDKLKGAREENSGL 1022
Query: 352 LFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSI 398
L Q+ E + + ++DK+ + E QI ++ TL+S+
Sbjct: 1023 L---QELEEL---RKQADKAKAAQTAEDAMQIMEQMTKEKTETLASL 1063
Score = 32.7 bits (73), Expect = 1.1
Identities = 34/154 (22%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 17 EVEISTIEKQRKELQLLIGE-LKDRDKE---LNDMVAVHQQQLLSWEEDRQKVLTLEERC 72
E E S + Q E++ + +KD D+E L +++ L + + +K L
Sbjct: 1154 EEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEK---LRNEV 1210
Query: 73 SKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLE 132
+ L GE +SL V+ LES++++ + ++ +LQL+E ++ + SS ++
Sbjct: 1211 TVLRGE----NASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQA 1266
Query: 133 ARNETLSNTLVE-LSAQVGQLQAREQALTTMIKL 165
+E + ++ L++ + LQ + Q L +++
Sbjct: 1267 DEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEM 1300
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 65.1 bits (157), Expect = 2e-10
Identities = 83/400 (20%), Positives = 166/400 (41%), Gaps = 36/400 (9%)
Query: 11 RQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEE 70
R+N+ +++E EK +E QL+ K ++K ND+ +++ D LT
Sbjct: 888 RENL-ADMEAKFREKDEREEQLI----KAKEKLENDIA-----EIMKMSGDNSSQLT--- 934
Query: 71 RCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHS-SLLSE 129
K+ EL + + L K+ N Q +++ ++ ++ Q+A +
Sbjct: 935 ---KMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKK 991
Query: 130 DLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNH-IADCSGKFKMLE 188
+LE + L + Q +L+AR + T+ K K ++I++ + + D K K
Sbjct: 992 ELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAR 1051
Query: 189 HALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTEN----NEQREEIIRLK 244
++ + + KQ K K + ++ E + ++ TE + ++ +L+
Sbjct: 1052 E--ENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQ 1109
Query: 245 QEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFL-NFNV 303
E L + L VE + ELL + K E E+ L+Q ++ L L NV
Sbjct: 1110 NELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENV 1169
Query: 304 ENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLV 363
+ ++EL + D K L+ R + + L ++ +K + KD E +
Sbjct: 1170 KLAEELGRSRDEVTSHQK-LEEERSVLNNQL--------LEMKKRESKFIKDADEEKASL 1220
Query: 364 QQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSIFTKDL 403
Q++ S S+ EK +++ + E +V+ + K L
Sbjct: 1221 QKSISITSAL--LTEKDAELEKLRNEVTVLRGENASAKSL 1258
Score = 61.6 bits (148), Expect = 2e-09
Identities = 68/375 (18%), Positives = 161/375 (42%), Gaps = 19/375 (5%)
Query: 19 EISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVL----TLEERCSK 74
++ EKQ K L++ + + + + +L + +E+ +V TLE+
Sbjct: 785 QLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQI 844
Query: 75 LEGELHKRTE----IIRSLTKKVKALESNQME---CQTALQKTQLQLQEMAQKATHSSLL 127
L+ + + +E + RS+ + V L + + + L+K + L +M K
Sbjct: 845 LKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDER 904
Query: 128 SEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKML 187
E L E L N + E+ G ++ + ++LK++D+ E + + L
Sbjct: 905 EEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFL 964
Query: 188 EHALRDAKM-AETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQE 246
+ ++ D + AE + + ++++ K L+ +++ L++ + + E + R E
Sbjct: 965 QKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSE 1024
Query: 247 KSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENS 306
H+E+L +++ E + K +E + L L ++ ++Q+D E++
Sbjct: 1025 TKTKHEEILQNLQKTLLDTE--DKLKGAREENSGLLQELEEL--RKQADKAKAAQTAEDA 1080
Query: 307 QELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQN 366
++++ + E+ A + L+N ++D +E N K++ + K + +L +N
Sbjct: 1081 MQIMEQMTKEKTETLASLEDTKQTNAKLQN---ELDTLKENNLKNVEELNKSKELLTVEN 1137
Query: 367 RSDKSSCDECKEKKQ 381
+ + E + KQ
Sbjct: 1138 QKMEEFRKEIETLKQ 1152
Score = 56.6 bits (135), Expect = 7e-08
Identities = 83/407 (20%), Positives = 169/407 (41%), Gaps = 58/407 (14%)
Query: 19 EISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGE 78
++ E + KEL++L + ++ K +++ + QL + EE + L + S+ + E
Sbjct: 723 KLQEAEIKVKELEVLQAKCNEQTKVIDNFTS----QLKATEEKLLDLDALRKASSEGKSE 778
Query: 79 LHKRTEIIRSLTKKVKALE-------SNQMECQTALQKTQLQLQEMAQKATHSSLLSEDL 131
+ K + + + K++K LE S LQ +L+L + + + S + E L
Sbjct: 779 MKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETL 838
Query: 132 EARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDK-------DIIEAVNHIADCSGKF 184
E + L E S + +Q Q + K++ D+ + ++AD KF
Sbjct: 839 EKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKF 898
Query: 185 KMLEHALRDAKMAETCIVKEKQDYKQKLKAL-------KIEVNKLKEDLNEKTTENNEQR 237
R+ E ++K K+ + + + ++ K+ ++L K + E +
Sbjct: 899 -------REKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQ 951
Query: 238 EEIIRLKQEKSCLHDELL-FTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDL 296
++ + + S L + TV+ E+ + E A K E EL ++ SDL
Sbjct: 952 LKLTKANENASFLQKSIEDMTVKAEQSQQE----AAKKHEEEKKELE-------RKLSDL 1000
Query: 297 Q-FLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLE----NNHPKVDIKREKNQKS 351
+ + + QEL Y+ E+K + + L +L+ + K+ RE+N
Sbjct: 1001 EKKMETSHNQCQELKARYERATSETK---TKHEEILQNLQKTLLDTEDKLKGAREENSGL 1057
Query: 352 LFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSI 398
L Q+ E + + ++DK+ + E QI ++ TL+S+
Sbjct: 1058 L---QELEEL---RKQADKAKAAQTAEDAMQIMEQMTKEKTETLASL 1098
Score = 40.8 bits (94), Expect = 0.004
Identities = 57/318 (17%), Positives = 132/318 (41%), Gaps = 48/318 (15%)
Query: 86 IRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNETLSNTLVEL 145
I T +AL+ Q + L + L+ E+A+ +H + ++L + ++EL
Sbjct: 347 ISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLEL 406
Query: 146 SAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMAETCIVKEK 205
A++ QL+ TM++ D++ +E +N +
Sbjct: 407 EAKMDQLR-------TMVEAADREKVELLNQL---------------------------- 431
Query: 206 QDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKD 265
++ K+K++ L+ V +E + + E + E + E+S L ++ ++ +R+
Sbjct: 432 EEEKRKVEDLQFRVE--EESITKGDLETQTKLEHARIKELEQSLLFEKT--KADKLQREL 487
Query: 266 ELLNIAKSKQERTNSELHNLRQIYVKQQSDL-QFLNFN-----VENSQELIQMYDSKMEE 319
E +A ++ EL + V++ ++L + L N V+ S L+Q S E+
Sbjct: 488 EDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEK 547
Query: 320 SKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEK 379
+ + ++ L+ + + +K K+L+ + L ++N S KS + ++
Sbjct: 548 LEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATE---KLSKENESLKSKLEHANKE 604
Query: 380 KQQIDTVFGEKSVITLSS 397
+ ++ K ++S
Sbjct: 605 NSDVIALWKSKLETAIAS 622
Score = 32.7 bits (73), Expect = 1.1
Identities = 34/154 (22%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 17 EVEISTIEKQRKELQLLIGE-LKDRDKE---LNDMVAVHQQQLLSWEEDRQKVLTLEERC 72
E E S + Q E++ + +KD D+E L +++ L + + +K L
Sbjct: 1189 EEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEK---LRNEV 1245
Query: 73 SKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLE 132
+ L GE +SL V+ LES++++ + ++ +LQL+E ++ + SS ++
Sbjct: 1246 TVLRGE----NASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQA 1301
Query: 133 ARNETLSNTLVE-LSAQVGQLQAREQALTTMIKL 165
+E + ++ L++ + LQ + Q L +++
Sbjct: 1302 DEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEM 1335
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.125 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,551,935
Number of Sequences: 37866
Number of extensions: 1135949
Number of successful extensions: 8515
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 236
Number of HSP's successfully gapped in prelim test: 784
Number of HSP's that attempted gapping in prelim test: 4647
Number of HSP's gapped (non-prelim): 2880
length of query: 684
length of database: 18,247,518
effective HSP length: 109
effective length of query: 575
effective length of database: 14,120,124
effective search space: 8119071300
effective search space used: 8119071300
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.