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Search of human proteins with 7549809
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7549809 plastin 3 [Homo sapiens]
(630 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209862851 plastin 3 [Homo sapiens] 1265 0.0
gi|7549809 plastin 3 [Homo sapiens] 1265 0.0
gi|167614506 L-plastin [Homo sapiens] 1028 0.0
gi|223718250 plastin 1 [Homo sapiens] 984 0.0
gi|223718246 plastin 1 [Homo sapiens] 984 0.0
gi|221316624 dystonin isoform 4 [Homo sapiens] 71 3e-12
gi|221316622 dystonin isoform 3 [Homo sapiens] 71 3e-12
gi|221316618 dystonin isoform 2 [Homo sapiens] 71 3e-12
gi|34577047 dystonin isoform 1 [Homo sapiens] 71 3e-12
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 69 1e-11
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [... 68 3e-11
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 66 1e-10
gi|5032281 dystrophin Dp427c isoform [Homo sapiens] 65 2e-10
gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens] 65 2e-10
gi|5032283 dystrophin Dp427m isoform [Homo sapiens] 65 2e-10
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 65 2e-10
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 65 2e-10
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 65 2e-10
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 65 2e-10
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 65 2e-10
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 65 2e-10
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ... 64 5e-10
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ... 64 5e-10
gi|67782321 spectrin beta isoform a [Homo sapiens] 62 2e-09
gi|67782319 spectrin beta isoform b [Homo sapiens] 62 2e-09
gi|169218211 PREDICTED: similar to plectin 1, partial [Homo sapi... 62 2e-09
gi|110611228 utrophin [Homo sapiens] 62 2e-09
gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens] 61 4e-09
gi|33188445 microfilament and actin filament cross-linker protei... 60 8e-09
gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens] 58 3e-08
>gi|209862851 plastin 3 [Homo sapiens]
Length = 630
Score = 1265 bits (3274), Expect = 0.0
Identities = 630/630 (100%), Positives = 630/630 (100%)
Query: 1 MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKL 60
MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKL
Sbjct: 1 MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKL 60
Query: 61 MLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHS 120
MLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHS
Sbjct: 61 MLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHS 120
Query: 121 YSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDE 180
YSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDE
Sbjct: 121 YSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDE 180
Query: 181 RAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLF 240
RAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLF
Sbjct: 181 RAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLF 240
Query: 241 ADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSK 300
ADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSK
Sbjct: 241 ADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSK 300
Query: 301 AYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVS 360
AYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVS
Sbjct: 301 AYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVS 360
Query: 361 GNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLY 420
GNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLY
Sbjct: 361 GNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLY 420
Query: 421 ADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVG 480
ADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVG
Sbjct: 421 ADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVG 480
Query: 481 IGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTS 540
IGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTS
Sbjct: 481 IGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTS 540
Query: 541 IQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARV 600
IQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARV
Sbjct: 541 IQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARV 600
Query: 601 YALPEDLVEVKPKMVMTVFACLMGRGMKRV 630
YALPEDLVEVKPKMVMTVFACLMGRGMKRV
Sbjct: 601 YALPEDLVEVKPKMVMTVFACLMGRGMKRV 630
>gi|7549809 plastin 3 [Homo sapiens]
Length = 630
Score = 1265 bits (3274), Expect = 0.0
Identities = 630/630 (100%), Positives = 630/630 (100%)
Query: 1 MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKL 60
MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKL
Sbjct: 1 MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKL 60
Query: 61 MLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHS 120
MLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHS
Sbjct: 61 MLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHS 120
Query: 121 YSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDE 180
YSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDE
Sbjct: 121 YSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDE 180
Query: 181 RAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLF 240
RAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLF
Sbjct: 181 RAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLF 240
Query: 241 ADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSK 300
ADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSK
Sbjct: 241 ADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSK 300
Query: 301 AYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVS 360
AYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVS
Sbjct: 301 AYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVS 360
Query: 361 GNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLY 420
GNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLY
Sbjct: 361 GNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLY 420
Query: 421 ADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVG 480
ADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVG
Sbjct: 421 ADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVG 480
Query: 481 IGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTS 540
IGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTS
Sbjct: 481 IGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTS 540
Query: 541 IQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARV 600
IQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARV
Sbjct: 541 IQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARV 600
Query: 601 YALPEDLVEVKPKMVMTVFACLMGRGMKRV 630
YALPEDLVEVKPKMVMTVFACLMGRGMKRV
Sbjct: 601 YALPEDLVEVKPKMVMTVFACLMGRGMKRV 630
>gi|167614506 L-plastin [Homo sapiens]
Length = 627
Score = 1028 bits (2657), Expect = 0.0
Identities = 501/627 (79%), Positives = 562/627 (89%)
Query: 4 MATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLD 63
MA +S +E+ EL+EAFAKVD + NG+I EL++LFK A +PLPGY+VREI + LM
Sbjct: 1 MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMAT 60
Query: 64 GDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSE 123
GD ++DG+ISFDEF+ IF +KS+D+AKTFRKAIN+KEGICA+GGTSE SS GTQHSYSE
Sbjct: 61 GDLDQDGRISFDEFIKIFHGLKSTDVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSE 120
Query: 124 EEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAI 183
EEKYAFVNWINKALENDPDCRHVIPMNPNT+DLF AVGDGIVLCKMINLSVPDTIDER I
Sbjct: 121 EEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTI 180
Query: 184 NKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADI 243
NKKKLTPF IQENLNLALNSASAIGCHVVNIGAEDL+ GKP+LVLGLLWQ+IKIGLFADI
Sbjct: 181 NKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADI 240
Query: 244 ELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYF 303
ELSRNEAL ALLR+GE+LE+LMKLSPEELLLRWAN+HLEN+G KI NFS DIKDSKAY+
Sbjct: 241 ELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYY 300
Query: 304 HLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNP 363
HLL Q+APKG +EG P + I+MSG E DD++RAE MLQQA++LGCRQFVT DVV GNP
Sbjct: 301 HLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNP 360
Query: 364 KLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADL 423
KLNLAF+ANLFN+YPAL KPENQDIDW LEGETREERTFRNWMNSLGVNP VNHLY+DL
Sbjct: 361 KLNLAFIANLFNRYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDL 420
Query: 424 QDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGG 483
DALVI QLYE+IKVPVDW++VNKPPYPKLG NMKKLENCNYAVELGK+ AKFSLVGIGG
Sbjct: 421 SDALVIFQLYEKIKVPVDWNRVNKPPYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGG 480
Query: 484 QDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTSIQS 543
QDLN+GN+TLTLAL+WQLMRRYTLN+LE++G GQK NDDIIVNWVN TL EA KS+SI S
Sbjct: 481 QDLNEGNRTLTLALIWQLMRRYTLNILEEIGGGQKVNDDIIVNWVNETLREAKKSSSISS 540
Query: 544 FKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYAL 603
FKD IS+SL V+DLIDAIQPG INYDL+K+ NL +D+K NNAKYA+SMAR+IGARVYAL
Sbjct: 541 FKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYAL 600
Query: 604 PEDLVEVKPKMVMTVFACLMGRGMKRV 630
PEDLVEV PKMVMTVFACLMG+GMKRV
Sbjct: 601 PEDLVEVNPKMVMTVFACLMGKGMKRV 627
>gi|223718250 plastin 1 [Homo sapiens]
Length = 629
Score = 984 bits (2545), Expect = 0.0
Identities = 473/628 (75%), Positives = 554/628 (88%), Gaps = 1/628 (0%)
Query: 3 EMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLML 62
E +TT IS++EL+EL+EAF K+D++++G++ DYEL +LFKEA++PLPGYKVREI++K++
Sbjct: 2 ENSTTTISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILS 61
Query: 63 DGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYS 122
D NKDGKISF+EFV + QE+KS DI+KTFRK IN++EGI A+GGTS +SSEGTQHSYS
Sbjct: 62 VADSNKDGKISFEEFVSLMQELKSKDISKTFRKIINKREGITAIGGTSTISSEGTQHSYS 121
Query: 123 EEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERA 182
EEEK AFVNWINKALENDPDC+H+IPMNPN D LFK++ DGI+LCKMINLS PDTIDERA
Sbjct: 122 EEEKVAFVNWINKALENDPDCKHLIPMNPNDDSLFKSLADGILLCKMINLSEPDTIDERA 181
Query: 183 INKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFAD 242
INKKKLTPF I ENLNLALNSASAIGC VVNIGA DL+ GKPHLVLGLLWQIIK+GLFAD
Sbjct: 182 INKKKLTPFTISENLNLALNSASAIGCTVVNIGASDLKEGKPHLVLGLLWQIIKVGLFAD 241
Query: 243 IELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAY 302
IE+SRNEAL ALL +GE LEELMKLSPEELLLRW N+HL N+GW I+NFS DIKDS+AY
Sbjct: 242 IEISRNEALIALLNEGEELEELMKLSPEELLLRWVNYHLTNAGWHTISNFSQDIKDSRAY 301
Query: 303 FHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGN 362
FHLLNQIAPKG ++G P I I++SG NET+DLKRA MLQ+ADKLGC+QFVTPADVVSGN
Sbjct: 302 FHLLNQIAPKGGEDG-PAIAIDLSGINETNDLKRAGLMLQEADKLGCKQFVTPADVVSGN 360
Query: 363 PKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYAD 422
PKLNLAFVANLFN YP L KP N DID LLEGE++EERTFRNWMNSLGVNP++NHLY+D
Sbjct: 361 PKLNLAFVANLFNTYPCLHKPNNNDIDMNLLEGESKEERTFRNWMNSLGVNPYINHLYSD 420
Query: 423 LQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIG 482
L DALVI QLYE I+VPV+WS VNKPPYP LG NMKK+ENCNYAVELGK+ AKFSLVGI
Sbjct: 421 LADALVIFQLYEMIRVPVNWSHVNKPPYPALGGNMKKIENCNYAVELGKNKAKFSLVGIA 480
Query: 483 GQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTSIQ 542
GQDLN+GN TLTLALVWQLMRRYTLNVL DLG+G+K ND+II+ WVN+TL A K TSI
Sbjct: 481 GQDLNEGNSTLTLALVWQLMRRYTLNVLSDLGEGEKVNDEIIIKWVNQTLKSANKKTSIS 540
Query: 543 SFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYA 602
SFKDK+IS+SL V+DLIDAI P + ++++ NL+++DK NNAKYA+S+AR+IGAR+YA
Sbjct: 541 SFKDKSISTSLPVLDLIDAIAPNAVRQEMIRRENLSDEDKLNNAKYAISVARKIGARIYA 600
Query: 603 LPEDLVEVKPKMVMTVFACLMGRGMKRV 630
LP+DLVEVKPKMVMTVFACLMG+G+ R+
Sbjct: 601 LPDDLVEVKPKMVMTVFACLMGKGLNRI 628
>gi|223718246 plastin 1 [Homo sapiens]
Length = 629
Score = 984 bits (2545), Expect = 0.0
Identities = 473/628 (75%), Positives = 554/628 (88%), Gaps = 1/628 (0%)
Query: 3 EMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLML 62
E +TT IS++EL+EL+EAF K+D++++G++ DYEL +LFKEA++PLPGYKVREI++K++
Sbjct: 2 ENSTTTISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILS 61
Query: 63 DGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYS 122
D NKDGKISF+EFV + QE+KS DI+KTFRK IN++EGI A+GGTS +SSEGTQHSYS
Sbjct: 62 VADSNKDGKISFEEFVSLMQELKSKDISKTFRKIINKREGITAIGGTSTISSEGTQHSYS 121
Query: 123 EEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERA 182
EEEK AFVNWINKALENDPDC+H+IPMNPN D LFK++ DGI+LCKMINLS PDTIDERA
Sbjct: 122 EEEKVAFVNWINKALENDPDCKHLIPMNPNDDSLFKSLADGILLCKMINLSEPDTIDERA 181
Query: 183 INKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFAD 242
INKKKLTPF I ENLNLALNSASAIGC VVNIGA DL+ GKPHLVLGLLWQIIK+GLFAD
Sbjct: 182 INKKKLTPFTISENLNLALNSASAIGCTVVNIGASDLKEGKPHLVLGLLWQIIKVGLFAD 241
Query: 243 IELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAY 302
IE+SRNEAL ALL +GE LEELMKLSPEELLLRW N+HL N+GW I+NFS DIKDS+AY
Sbjct: 242 IEISRNEALIALLNEGEELEELMKLSPEELLLRWVNYHLTNAGWHTISNFSQDIKDSRAY 301
Query: 303 FHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGN 362
FHLLNQIAPKG ++G P I I++SG NET+DLKRA MLQ+ADKLGC+QFVTPADVVSGN
Sbjct: 302 FHLLNQIAPKGGEDG-PAIAIDLSGINETNDLKRAGLMLQEADKLGCKQFVTPADVVSGN 360
Query: 363 PKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYAD 422
PKLNLAFVANLFN YP L KP N DID LLEGE++EERTFRNWMNSLGVNP++NHLY+D
Sbjct: 361 PKLNLAFVANLFNTYPCLHKPNNNDIDMNLLEGESKEERTFRNWMNSLGVNPYINHLYSD 420
Query: 423 LQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIG 482
L DALVI QLYE I+VPV+WS VNKPPYP LG NMKK+ENCNYAVELGK+ AKFSLVGI
Sbjct: 421 LADALVIFQLYEMIRVPVNWSHVNKPPYPALGGNMKKIENCNYAVELGKNKAKFSLVGIA 480
Query: 483 GQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTSIQ 542
GQDLN+GN TLTLALVWQLMRRYTLNVL DLG+G+K ND+II+ WVN+TL A K TSI
Sbjct: 481 GQDLNEGNSTLTLALVWQLMRRYTLNVLSDLGEGEKVNDEIIIKWVNQTLKSANKKTSIS 540
Query: 543 SFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYA 602
SFKDK+IS+SL V+DLIDAI P + ++++ NL+++DK NNAKYA+S+AR+IGAR+YA
Sbjct: 541 SFKDKSISTSLPVLDLIDAIAPNAVRQEMIRRENLSDEDKLNNAKYAISVARKIGARIYA 600
Query: 603 LPEDLVEVKPKMVMTVFACLMGRGMKRV 630
LP+DLVEVKPKMVMTVFACLMG+G+ R+
Sbjct: 601 LPDDLVEVKPKMVMTVFACLMGKGLNRI 628
>gi|221316624 dystonin isoform 4 [Homo sapiens]
Length = 5526
Score = 70.9 bits (172), Expect = 3e-12
Identities = 73/304 (24%), Positives = 126/304 (41%), Gaps = 62/304 (20%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K F WIN+ H++ + + +DL++ + DG L ++ + DT+
Sbjct: 66 QKKTFTKWINQ---------HLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPR---- 112
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
+K F +N+ +AL+ +VNI +D+ G P L LGL+W II +DI
Sbjct: 113 EKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIH 172
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFH 304
++ GE+ + +S +E LL W E + NF+ +D K +
Sbjct: 173 VT-----------GESED----MSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNA 217
Query: 305 LLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNP- 363
++++ P ID+N +L E A+K+G + + P DV +P
Sbjct: 218 IIHKYRP-------DLIDMNTVAVQ--SNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPD 268
Query: 364 -KLNLAFVANLFNKYPALTKPE---------------------NQDIDWTLLEGETREER 401
K + +V++L++ +P + PE N I W T ER
Sbjct: 269 EKSVITYVSSLYDAFPKV--PEGGEGIGANDVEVKWIEYQNMVNYLIQWIRHHVTTMSER 326
Query: 402 TFRN 405
TF N
Sbjct: 327 TFPN 330
Score = 57.4 bits (137), Expect = 4e-08
Identities = 56/234 (23%), Positives = 101/234 (43%), Gaps = 20/234 (8%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E + +++TF W+N + V HVN LY DL+D ++ L E + + P
Sbjct: 61 ERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSG-------DTLPRE 113
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLE 511
K +L+N A++ K + LV I D+ DGN LTL L+W ++ + ++ +
Sbjct: 114 KGRMRFHRLQNVQIALDYLKR-RQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIH 172
Query: 512 DLGDGQKAN-DDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYD 570
G+ + + + ++ W + +E ++F L +I +P D
Sbjct: 173 VTGESEDMSAKERLLLWTQQA-TEGYAGIRCENFTTCWRDGKLFNA-IIHKYRP-----D 225
Query: 571 LVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKP--KMVMTVFACL 622
L+ + N ++A +A +IG PED+ P K V+T + L
Sbjct: 226 LIDMNTVAVQSNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPDEKSVITYVSSL 279
>gi|221316622 dystonin isoform 3 [Homo sapiens]
Length = 5537
Score = 70.9 bits (172), Expect = 3e-12
Identities = 73/304 (24%), Positives = 126/304 (41%), Gaps = 62/304 (20%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K F WIN+ H++ + + +DL++ + DG L ++ + DT+
Sbjct: 77 QKKTFTKWINQ---------HLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPR---- 123
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
+K F +N+ +AL+ +VNI +D+ G P L LGL+W II +DI
Sbjct: 124 EKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIH 183
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFH 304
++ GE+ + +S +E LL W E + NF+ +D K +
Sbjct: 184 VT-----------GESED----MSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNA 228
Query: 305 LLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNP- 363
++++ P ID+N +L E A+K+G + + P DV +P
Sbjct: 229 IIHKYRP-------DLIDMNTVAVQ--SNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPD 279
Query: 364 -KLNLAFVANLFNKYPALTKPE---------------------NQDIDWTLLEGETREER 401
K + +V++L++ +P + PE N I W T ER
Sbjct: 280 EKSVITYVSSLYDAFPKV--PEGGEGIGANDVEVKWIEYQNMVNYLIQWIRHHVTTMSER 337
Query: 402 TFRN 405
TF N
Sbjct: 338 TFPN 341
Score = 57.4 bits (137), Expect = 4e-08
Identities = 56/234 (23%), Positives = 101/234 (43%), Gaps = 20/234 (8%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E + +++TF W+N + V HVN LY DL+D ++ L E + + P
Sbjct: 72 ERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSG-------DTLPRE 124
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLE 511
K +L+N A++ K + LV I D+ DGN LTL L+W ++ + ++ +
Sbjct: 125 KGRMRFHRLQNVQIALDYLKR-RQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIH 183
Query: 512 DLGDGQKAN-DDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYD 570
G+ + + + ++ W + +E ++F L +I +P D
Sbjct: 184 VTGESEDMSAKERLLLWTQQA-TEGYAGIRCENFTTCWRDGKLFNA-IIHKYRP-----D 236
Query: 571 LVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKP--KMVMTVFACL 622
L+ + N ++A +A +IG PED+ P K V+T + L
Sbjct: 237 LIDMNTVAVQSNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPDEKSVITYVSSL 290
>gi|221316618 dystonin isoform 2 [Homo sapiens]
Length = 5675
Score = 70.9 bits (172), Expect = 3e-12
Identities = 73/304 (24%), Positives = 126/304 (41%), Gaps = 62/304 (20%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K F WIN+ H++ + + +DL++ + DG L ++ + DT+
Sbjct: 215 QKKTFTKWINQ---------HLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPR---- 261
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
+K F +N+ +AL+ +VNI +D+ G P L LGL+W II +DI
Sbjct: 262 EKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIH 321
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFH 304
++ GE+ + +S +E LL W E + NF+ +D K +
Sbjct: 322 VT-----------GESED----MSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNA 366
Query: 305 LLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNP- 363
++++ P ID+N +L E A+K+G + + P DV +P
Sbjct: 367 IIHKYRP-------DLIDMNTVAVQ--SNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPD 417
Query: 364 -KLNLAFVANLFNKYPALTKPE---------------------NQDIDWTLLEGETREER 401
K + +V++L++ +P + PE N I W T ER
Sbjct: 418 EKSVITYVSSLYDAFPKV--PEGGEGIGANDVEVKWIEYQNMVNYLIQWIRHHVTTMSER 475
Query: 402 TFRN 405
TF N
Sbjct: 476 TFPN 479
Score = 57.4 bits (137), Expect = 4e-08
Identities = 56/234 (23%), Positives = 101/234 (43%), Gaps = 20/234 (8%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E + +++TF W+N + V HVN LY DL+D ++ L E + + P
Sbjct: 210 ERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSG-------DTLPRE 262
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLE 511
K +L+N A++ K + LV I D+ DGN LTL L+W ++ + ++ +
Sbjct: 263 KGRMRFHRLQNVQIALDYLKR-RQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIH 321
Query: 512 DLGDGQKAN-DDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYD 570
G+ + + + ++ W + +E ++F L +I +P D
Sbjct: 322 VTGESEDMSAKERLLLWTQQA-TEGYAGIRCENFTTCWRDGKLFNA-IIHKYRP-----D 374
Query: 571 LVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKP--KMVMTVFACL 622
L+ + N ++A +A +IG PED+ P K V+T + L
Sbjct: 375 LIDMNTVAVQSNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPDEKSVITYVSSL 428
>gi|34577047 dystonin isoform 1 [Homo sapiens]
Length = 5497
Score = 70.9 bits (172), Expect = 3e-12
Identities = 73/304 (24%), Positives = 126/304 (41%), Gaps = 62/304 (20%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K F WIN+ H++ + + +DL++ + DG L ++ + DT+
Sbjct: 37 QKKTFTKWINQ---------HLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPR---- 83
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
+K F +N+ +AL+ +VNI +D+ G P L LGL+W II +DI
Sbjct: 84 EKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIH 143
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFH 304
++ GE+ + +S +E LL W E + NF+ +D K +
Sbjct: 144 VT-----------GESED----MSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNA 188
Query: 305 LLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNP- 363
++++ P ID+N +L E A+K+G + + P DV +P
Sbjct: 189 IIHKYRP-------DLIDMNTVAVQ--SNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPD 239
Query: 364 -KLNLAFVANLFNKYPALTKPE---------------------NQDIDWTLLEGETREER 401
K + +V++L++ +P + PE N I W T ER
Sbjct: 240 EKSVITYVSSLYDAFPKV--PEGGEGIGANDVEVKWIEYQNMVNYLIQWIRHHVTTMSER 297
Query: 402 TFRN 405
TF N
Sbjct: 298 TFPN 301
Score = 57.4 bits (137), Expect = 4e-08
Identities = 56/234 (23%), Positives = 101/234 (43%), Gaps = 20/234 (8%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E + +++TF W+N + V HVN LY DL+D ++ L E + + P
Sbjct: 32 ERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSG-------DTLPRE 84
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLE 511
K +L+N A++ K + LV I D+ DGN LTL L+W ++ + ++ +
Sbjct: 85 KGRMRFHRLQNVQIALDYLKR-RQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIH 143
Query: 512 DLGDGQKAN-DDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYD 570
G+ + + + ++ W + +E ++F L +I +P D
Sbjct: 144 VTGESEDMSAKERLLLWTQQA-TEGYAGIRCENFTTCWRDGKLFNA-IIHKYRP-----D 196
Query: 571 LVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKP--KMVMTVFACL 622
L+ + N ++A +A +IG PED+ P K V+T + L
Sbjct: 197 LIDMNTVAVQSNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPDEKSVITYVSSL 250
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 68.9 bits (167), Expect = 1e-11
Identities = 64/278 (23%), Positives = 127/278 (45%), Gaps = 42/278 (15%)
Query: 113 SSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINL 172
+SEG + +K F W+NK H+I + DL++ + DG L ++ +
Sbjct: 32 ASEGKKDERDRVQKKTFTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLLEV 82
Query: 173 SVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLW 232
D++ +K F +N+ +AL+ +VNI +D+ G P L LGL+W
Sbjct: 83 LSGDSLPR----EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIW 138
Query: 233 QIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNF 292
II +DI++S G++ + ++ +E LL W+ +E + +NF
Sbjct: 139 TIILHFQISDIQVS-----------GQSED----MTAKEKLLLWSQRMVEGYQGLRCDNF 183
Query: 293 SADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADK-LGCRQ 351
++ +D + + ++++ P + I+M+ +L+ + A++ LG +
Sbjct: 184 TSSWRDGRLFNAIIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGVTR 234
Query: 352 FVTPADVVSGNP--KLNLAFVANLFNKYPALTKPENQD 387
+ P DV P K + +V++L++ P + P+ QD
Sbjct: 235 LLDPEDVDVPQPDEKSIITYVSSLYDAMPRV--PDVQD 270
Score = 53.1 bits (126), Expect = 7e-07
Identities = 33/126 (26%), Positives = 61/126 (48%), Gaps = 10/126 (7%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E + +++TF W+N + H++ LY DL+D ++ L E + + P
Sbjct: 39 ERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSG-------DSLPRE 91
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLE 511
K KL+N A++ +H + LV I D+ DGN LTL L+W ++ + ++ ++
Sbjct: 92 KGRMRFHKLQNVQIALDYLRH-RQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 150
Query: 512 DLGDGQ 517
G +
Sbjct: 151 VSGQSE 156
>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1
[Homo sapiens]
Length = 2564
Score = 67.8 bits (164), Expect = 3e-11
Identities = 66/223 (29%), Positives = 105/223 (47%), Gaps = 26/223 (11%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E E +++TF W+NS V H+ LY DL+D V+ +L E + + P P
Sbjct: 58 EREAVQKKTFTKWVNSHLARVGCHIGDLYVDLRDGFVLTRLLEVLSG-------EQLPRP 110
Query: 452 KLGA-NMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVL 510
G + LEN + A++ K + L +G D+ DGN LTL LVW ++ R+ + V+
Sbjct: 111 TRGRMRIHSLENVDKALQFLKEQ-RVHLENVGSHDIVDGNHRLTLGLVWTIILRFQIQVI 169
Query: 511 ----EDLGDGQKANDDIIVNWVNRTLSEAG-KSTSIQSFKDKTISSSLAVVDLIDAIQPG 565
ED + + A D +++ W + AG +IQ+F + LA LI +P
Sbjct: 170 KIETEDNRETRSAKDALLL-WCQ--MKTAGYPEVNIQNF-TTSWRDGLAFNALIHRHRP- 224
Query: 566 CINYDLVKSGNLTEDDKHNNAKYAVSMA-RRIGARVYALPEDL 607
DLV LT+ + + N + A A + +G PED+
Sbjct: 225 ----DLVDFSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDV 263
Score = 53.1 bits (126), Expect = 7e-07
Identities = 56/258 (21%), Positives = 111/258 (43%), Gaps = 41/258 (15%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K F W+N H+ + + DL+ + DG VL +++ + + +
Sbjct: 63 QKKTFTKWVNS---------HLARVGCHIGDLYVDLRDGFVLTRLLEVLSGEQLPRPTRG 113
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
+ ++ EN++ AL H+ N+G+ D+ G L LGL+W II I+
Sbjct: 114 RMRIHSL---ENVDKALQFLKEQRVHLENVGSHDIVDGNHRLTLGLVWTIILRFQIQVIK 170
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKIN--NFSADIKDSKAY 302
+ ET + S ++ LL W ++ +G+ ++N NF+ +D A+
Sbjct: 171 I-------------ETEDNRETRSAKDALLLWC--QMKTAGYPEVNIQNFTTSWRDGLAF 215
Query: 303 FHLLNQIAPKGQKEGEPRIDIN-MSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSG 361
L+++ P +D + ++ N +L+RA +Q LG + + P DV
Sbjct: 216 NALIHRHRP-------DLVDFSKLTKSNANYNLQRAFRTAEQ--HLGLARLLDPEDVNME 266
Query: 362 NP--KLNLAFVANLFNKY 377
P K + +V + ++ +
Sbjct: 267 APDEKSIITYVVSFYHYF 284
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 65.9 bits (159), Expect = 1e-10
Identities = 64/280 (22%), Positives = 127/280 (45%), Gaps = 46/280 (16%)
Query: 115 EGTQHSYSEE----EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMI 170
E + Y +E +K F W+NK H+I + DL++ + DG L ++
Sbjct: 16 EEVREKYKDERDRVQKKTFTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLL 66
Query: 171 NLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGL 230
+ D++ +K F +N+ +AL+ +VNI +D+ G P L LGL
Sbjct: 67 EVLSGDSLPR----EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGL 122
Query: 231 LWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKIN 290
+W II +DI++S G++ + ++ +E LL W+ +E + +
Sbjct: 123 IWTIILHFQISDIQVS-----------GQSED----MTAKEKLLLWSQRMVEGYQGLRCD 167
Query: 291 NFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADK-LGC 349
NF++ +D + + ++++ P + I+M+ +L+ + A++ LG
Sbjct: 168 NFTSSWRDGRLFNAIIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGV 218
Query: 350 RQFVTPADVVSGNP--KLNLAFVANLFNKYPALTKPENQD 387
+ + P DV P K + +V++L++ P + P+ QD
Sbjct: 219 TRLLDPEDVDVPQPDEKSIITYVSSLYDAMPRV--PDVQD 256
Score = 53.1 bits (126), Expect = 7e-07
Identities = 33/126 (26%), Positives = 61/126 (48%), Gaps = 10/126 (7%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E + +++TF W+N + H++ LY DL+D ++ L E + + P
Sbjct: 25 ERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSG-------DSLPRE 77
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLE 511
K KL+N A++ +H + LV I D+ DGN LTL L+W ++ + ++ ++
Sbjct: 78 KGRMRFHKLQNVQIALDYLRH-RQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 136
Query: 512 DLGDGQ 517
G +
Sbjct: 137 VSGQSE 142
>gi|5032281 dystrophin Dp427c isoform [Homo sapiens]
Length = 3677
Score = 65.1 bits (157), Expect = 2e-10
Identities = 59/226 (26%), Positives = 108/226 (47%), Gaps = 21/226 (9%)
Query: 394 EGETREERTFRNWMN---SLGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPY 450
E E +++TF W+N S H+ +L++DLQD +L L E + K P
Sbjct: 4 EREDVQKKTFTKWVNAQFSKFGKQHIENLFSDLQDGRRLLDLLEGLTG-------QKLPK 56
Query: 451 PKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTL-NV 509
K + L N N A+ + ++ LV IG D+ DGN LTL L+W ++ + + NV
Sbjct: 57 EKGSTRVHALNNVNKALRVLQNN-NVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNV 115
Query: 510 LEDLGDG--QKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCI 567
++++ G Q ++ I+++WV ++ + I + S LA+ LI + +P
Sbjct: 116 MKNIMAGLQQTNSEKILLSWVRQSTRNYPQVNVINF--TTSWSDGLALNALIHSHRPDLF 173
Query: 568 NYDLVKSGNLTEDDKHNNAKYAVSMAR-RIGARVYALPEDLVEVKP 612
+++ V + + ++A ++AR ++G PED+ P
Sbjct: 174 DWNSV----VCQQSATQRLEHAFNIARYQLGIEKLLDPEDVDTTYP 215
Score = 43.9 bits (102), Expect = 5e-04
Identities = 58/261 (22%), Positives = 98/261 (37%), Gaps = 44/261 (16%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K F W+N +H+ ++LF + DG L ++ ++
Sbjct: 9 QKKTFTKWVNAQFSKFGK-QHI-------ENLFSDLQDGRRLLDLLE----GLTGQKLPK 56
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
+K T N+N AL +VNIG+ D+ G L LGL+W II L ++
Sbjct: 57 EKGSTRVHALNNVNKALRVLQNNNVDLVNIGSTDIVDGNHKLTLGLIWNII---LHWQVK 113
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFH 304
+A L + + E++LL W N + NF+ D A
Sbjct: 114 NVMKNIMAG----------LQQTNSEKILLSWVRQSTRNYPQVNVINFTTSWSDGLALNA 163
Query: 305 LLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQA-----DKLGCRQFVTPADVV 359
L++ P ++ +N + A L+ A +LG + + P DV
Sbjct: 164 LIHSHRP------------DLFDWNSVVCQQSATQRLEHAFNIARYQLGIEKLLDPEDVD 211
Query: 360 SGNP--KLNLAFVANLFNKYP 378
+ P K L ++ +LF P
Sbjct: 212 TTYPDKKSILMYITSLFQVLP 232
>gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]
Length = 3681
Score = 65.1 bits (157), Expect = 2e-10
Identities = 59/226 (26%), Positives = 108/226 (47%), Gaps = 21/226 (9%)
Query: 394 EGETREERTFRNWMN---SLGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPY 450
E E +++TF W+N S H+ +L++DLQD +L L E + K P
Sbjct: 8 EREDVQKKTFTKWVNAQFSKFGKQHIENLFSDLQDGRRLLDLLEGLTG-------QKLPK 60
Query: 451 PKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTL-NV 509
K + L N N A+ + ++ LV IG D+ DGN LTL L+W ++ + + NV
Sbjct: 61 EKGSTRVHALNNVNKALRVLQNN-NVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNV 119
Query: 510 LEDLGDG--QKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCI 567
++++ G Q ++ I+++WV ++ + I + S LA+ LI + +P
Sbjct: 120 MKNIMAGLQQTNSEKILLSWVRQSTRNYPQVNVINF--TTSWSDGLALNALIHSHRPDLF 177
Query: 568 NYDLVKSGNLTEDDKHNNAKYAVSMAR-RIGARVYALPEDLVEVKP 612
+++ V + + ++A ++AR ++G PED+ P
Sbjct: 178 DWNSV----VCQQSATQRLEHAFNIARYQLGIEKLLDPEDVDTTYP 219
Score = 45.4 bits (106), Expect = 2e-04
Identities = 60/272 (22%), Positives = 102/272 (37%), Gaps = 44/272 (16%)
Query: 114 SEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLS 173
SE + + +K F W+N +H+ ++LF + DG L ++
Sbjct: 2 SEVSSDEREDVQKKTFTKWVNAQFSKFGK-QHI-------ENLFSDLQDGRRLLDLLE-- 51
Query: 174 VPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQ 233
++ +K T N+N AL +VNIG+ D+ G L LGL+W
Sbjct: 52 --GLTGQKLPKEKGSTRVHALNNVNKALRVLQNNNVDLVNIGSTDIVDGNHKLTLGLIWN 109
Query: 234 IIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFS 293
II L ++ +A L + + E++LL W N + NF+
Sbjct: 110 II---LHWQVKNVMKNIMAG----------LQQTNSEKILLSWVRQSTRNYPQVNVINFT 156
Query: 294 ADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQA-----DKLG 348
D A L++ P ++ +N + A L+ A +LG
Sbjct: 157 TSWSDGLALNALIHSHRP------------DLFDWNSVVCQQSATQRLEHAFNIARYQLG 204
Query: 349 CRQFVTPADVVSGNP--KLNLAFVANLFNKYP 378
+ + P DV + P K L ++ +LF P
Sbjct: 205 IEKLLDPEDVDTTYPDKKSILMYITSLFQVLP 236
>gi|5032283 dystrophin Dp427m isoform [Homo sapiens]
Length = 3685
Score = 65.1 bits (157), Expect = 2e-10
Identities = 59/226 (26%), Positives = 108/226 (47%), Gaps = 21/226 (9%)
Query: 394 EGETREERTFRNWMN---SLGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPY 450
E E +++TF W+N S H+ +L++DLQD +L L E + K P
Sbjct: 12 EREDVQKKTFTKWVNAQFSKFGKQHIENLFSDLQDGRRLLDLLEGLTG-------QKLPK 64
Query: 451 PKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTL-NV 509
K + L N N A+ + ++ LV IG D+ DGN LTL L+W ++ + + NV
Sbjct: 65 EKGSTRVHALNNVNKALRVLQNN-NVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNV 123
Query: 510 LEDLGDG--QKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCI 567
++++ G Q ++ I+++WV ++ + I + S LA+ LI + +P
Sbjct: 124 MKNIMAGLQQTNSEKILLSWVRQSTRNYPQVNVINF--TTSWSDGLALNALIHSHRPDLF 181
Query: 568 NYDLVKSGNLTEDDKHNNAKYAVSMAR-RIGARVYALPEDLVEVKP 612
+++ V + + ++A ++AR ++G PED+ P
Sbjct: 182 DWNSV----VCQQSATQRLEHAFNIARYQLGIEKLLDPEDVDTTYP 223
Score = 44.7 bits (104), Expect = 3e-04
Identities = 61/273 (22%), Positives = 102/273 (37%), Gaps = 46/273 (16%)
Query: 115 EGTQHSYSEEE--KYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINL 172
E + Y E+ K F W+N +H+ ++LF + DG L ++
Sbjct: 5 EEVEDCYEREDVQKKTFTKWVNAQFSKFGK-QHI-------ENLFSDLQDGRRLLDLLE- 55
Query: 173 SVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLW 232
++ +K T N+N AL +VNIG+ D+ G L LGL+W
Sbjct: 56 ---GLTGQKLPKEKGSTRVHALNNVNKALRVLQNNNVDLVNIGSTDIVDGNHKLTLGLIW 112
Query: 233 QIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNF 292
II L ++ +A L + + E++LL W N + NF
Sbjct: 113 NII---LHWQVKNVMKNIMAG----------LQQTNSEKILLSWVRQSTRNYPQVNVINF 159
Query: 293 SADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQA-----DKL 347
+ D A L++ P ++ +N + A L+ A +L
Sbjct: 160 TTSWSDGLALNALIHSHRP------------DLFDWNSVVCQQSATQRLEHAFNIARYQL 207
Query: 348 GCRQFVTPADVVSGNP--KLNLAFVANLFNKYP 378
G + + P DV + P K L ++ +LF P
Sbjct: 208 GIEKLLDPEDVDTTYPDKKSILMYITSLFQVLP 240
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 65.1 bits (157), Expect = 2e-10
Identities = 62/277 (22%), Positives = 125/277 (45%), Gaps = 42/277 (15%)
Query: 114 SEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLS 173
++ Q +K F W+NK H+I + DL++ + DG L ++ +
Sbjct: 33 AQDEQDERDRVQKKTFTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLLEVL 83
Query: 174 VPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQ 233
D++ +K F +N+ +AL+ +VNI +D+ G P L LGL+W
Sbjct: 84 SGDSLPR----EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWT 139
Query: 234 IIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFS 293
II +DI++S G++ + ++ +E LL W+ +E + +NF+
Sbjct: 140 IILHFQISDIQVS-----------GQSED----MTAKEKLLLWSQRMVEGYQGLRCDNFT 184
Query: 294 ADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADK-LGCRQF 352
+ +D + + ++++ P + I+M+ +L+ + A++ LG +
Sbjct: 185 SSWRDGRLFNAIIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRL 235
Query: 353 VTPADVVSGNP--KLNLAFVANLFNKYPALTKPENQD 387
+ P DV P K + +V++L++ P + P+ QD
Sbjct: 236 LDPEDVDVPQPDEKSIITYVSSLYDAMPRV--PDVQD 270
Score = 53.1 bits (126), Expect = 7e-07
Identities = 33/126 (26%), Positives = 61/126 (48%), Gaps = 10/126 (7%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E + +++TF W+N + H++ LY DL+D ++ L E + + P
Sbjct: 39 ERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSG-------DSLPRE 91
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLE 511
K KL+N A++ +H + LV I D+ DGN LTL L+W ++ + ++ ++
Sbjct: 92 KGRMRFHKLQNVQIALDYLRH-RQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 150
Query: 512 DLGDGQ 517
G +
Sbjct: 151 VSGQSE 156
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 64.7 bits (156), Expect = 2e-10
Identities = 61/266 (22%), Positives = 122/266 (45%), Gaps = 42/266 (15%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K F W+NK H+I + DL++ + DG L ++ + D++
Sbjct: 48 QKKTFTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPR---- 94
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
+K F +N+ +AL+ +VNI +D+ G P L LGL+W II +DI+
Sbjct: 95 EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 154
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFH 304
+S G++ + ++ +E LL W+ +E + +NF++ +D + +
Sbjct: 155 VS-----------GQSED----MTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA 199
Query: 305 LLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADK-LGCRQFVTPADVVSGNP 363
++++ P + I+M+ +L+ + A++ LG + + P DV P
Sbjct: 200 IIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQP 250
Query: 364 --KLNLAFVANLFNKYPALTKPENQD 387
K + +V++L++ P + P+ QD
Sbjct: 251 DEKSIITYVSSLYDAMPRV--PDVQD 274
Score = 53.1 bits (126), Expect = 7e-07
Identities = 33/126 (26%), Positives = 61/126 (48%), Gaps = 10/126 (7%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E + +++TF W+N + H++ LY DL+D ++ L E + + P
Sbjct: 43 ERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSG-------DSLPRE 95
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLE 511
K KL+N A++ +H + LV I D+ DGN LTL L+W ++ + ++ ++
Sbjct: 96 KGRMRFHKLQNVQIALDYLRH-RQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 154
Query: 512 DLGDGQ 517
G +
Sbjct: 155 VSGQSE 160
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 64.7 bits (156), Expect = 2e-10
Identities = 61/266 (22%), Positives = 122/266 (45%), Gaps = 42/266 (15%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K F W+NK H+I + DL++ + DG L ++ + D++
Sbjct: 12 QKKTFTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPR---- 58
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
+K F +N+ +AL+ +VNI +D+ G P L LGL+W II +DI+
Sbjct: 59 EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 118
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFH 304
+S G++ + ++ +E LL W+ +E + +NF++ +D + +
Sbjct: 119 VS-----------GQSED----MTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA 163
Query: 305 LLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADK-LGCRQFVTPADVVSGNP 363
++++ P + I+M+ +L+ + A++ LG + + P DV P
Sbjct: 164 IIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQP 214
Query: 364 --KLNLAFVANLFNKYPALTKPENQD 387
K + +V++L++ P + P+ QD
Sbjct: 215 DEKSIITYVSSLYDAMPRV--PDVQD 238
Score = 53.1 bits (126), Expect = 7e-07
Identities = 33/126 (26%), Positives = 61/126 (48%), Gaps = 10/126 (7%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E + +++TF W+N + H++ LY DL+D ++ L E + + P
Sbjct: 7 ERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSG-------DSLPRE 59
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLE 511
K KL+N A++ +H + LV I D+ DGN LTL L+W ++ + ++ ++
Sbjct: 60 KGRMRFHKLQNVQIALDYLRH-RQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 118
Query: 512 DLGDGQ 517
G +
Sbjct: 119 VSGQSE 124
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 64.7 bits (156), Expect = 2e-10
Identities = 61/266 (22%), Positives = 122/266 (45%), Gaps = 42/266 (15%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K F W+NK H+I + DL++ + DG L ++ + D++
Sbjct: 181 QKKTFTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPR---- 227
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
+K F +N+ +AL+ +VNI +D+ G P L LGL+W II +DI+
Sbjct: 228 EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 287
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFH 304
+S G++ + ++ +E LL W+ +E + +NF++ +D + +
Sbjct: 288 VS-----------GQSED----MTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA 332
Query: 305 LLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADK-LGCRQFVTPADVVSGNP 363
++++ P + I+M+ +L+ + A++ LG + + P DV P
Sbjct: 333 IIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQP 383
Query: 364 --KLNLAFVANLFNKYPALTKPENQD 387
K + +V++L++ P + P+ QD
Sbjct: 384 DEKSIITYVSSLYDAMPRV--PDVQD 407
Score = 53.1 bits (126), Expect = 7e-07
Identities = 33/126 (26%), Positives = 61/126 (48%), Gaps = 10/126 (7%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E + +++TF W+N + H++ LY DL+D ++ L E + + P
Sbjct: 176 ERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSG-------DSLPRE 228
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLE 511
K KL+N A++ +H + LV I D+ DGN LTL L+W ++ + ++ ++
Sbjct: 229 KGRMRFHKLQNVQIALDYLRH-RQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 287
Query: 512 DLGDGQ 517
G +
Sbjct: 288 VSGQSE 293
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 64.7 bits (156), Expect = 2e-10
Identities = 61/266 (22%), Positives = 122/266 (45%), Gaps = 42/266 (15%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K F W+NK H+I + DL++ + DG L ++ + D++
Sbjct: 22 QKKTFTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPR---- 68
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
+K F +N+ +AL+ +VNI +D+ G P L LGL+W II +DI+
Sbjct: 69 EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 128
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFH 304
+S G++ + ++ +E LL W+ +E + +NF++ +D + +
Sbjct: 129 VS-----------GQSED----MTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA 173
Query: 305 LLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADK-LGCRQFVTPADVVSGNP 363
++++ P + I+M+ +L+ + A++ LG + + P DV P
Sbjct: 174 IIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQP 224
Query: 364 --KLNLAFVANLFNKYPALTKPENQD 387
K + +V++L++ P + P+ QD
Sbjct: 225 DEKSIITYVSSLYDAMPRV--PDVQD 248
Score = 53.1 bits (126), Expect = 7e-07
Identities = 33/126 (26%), Positives = 61/126 (48%), Gaps = 10/126 (7%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E + +++TF W+N + H++ LY DL+D ++ L E + + P
Sbjct: 17 ERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSG-------DSLPRE 69
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLE 511
K KL+N A++ +H + LV I D+ DGN LTL L+W ++ + ++ ++
Sbjct: 70 KGRMRFHKLQNVQIALDYLRH-RQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 128
Query: 512 DLGDGQ 517
G +
Sbjct: 129 VSGQSE 134
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 64.7 bits (156), Expect = 2e-10
Identities = 61/266 (22%), Positives = 122/266 (45%), Gaps = 42/266 (15%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K F W+NK H+I + DL++ + DG L ++ + D++
Sbjct: 71 QKKTFTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPR---- 117
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
+K F +N+ +AL+ +VNI +D+ G P L LGL+W II +DI+
Sbjct: 118 EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 177
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFH 304
+S G++ + ++ +E LL W+ +E + +NF++ +D + +
Sbjct: 178 VS-----------GQSED----MTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA 222
Query: 305 LLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADK-LGCRQFVTPADVVSGNP 363
++++ P + I+M+ +L+ + A++ LG + + P DV P
Sbjct: 223 IIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQP 273
Query: 364 --KLNLAFVANLFNKYPALTKPENQD 387
K + +V++L++ P + P+ QD
Sbjct: 274 DEKSIITYVSSLYDAMPRV--PDVQD 297
Score = 53.1 bits (126), Expect = 7e-07
Identities = 33/126 (26%), Positives = 61/126 (48%), Gaps = 10/126 (7%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E + +++TF W+N + H++ LY DL+D ++ L E + + P
Sbjct: 66 ERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSG-------DSLPRE 118
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLE 511
K KL+N A++ +H + LV I D+ DGN LTL L+W ++ + ++ ++
Sbjct: 119 KGRMRFHKLQNVQIALDYLRH-RQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 177
Query: 512 DLGDGQ 517
G +
Sbjct: 178 VSGQSE 183
>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
sapiens]
Length = 2155
Score = 63.5 bits (153), Expect = 5e-10
Identities = 59/222 (26%), Positives = 109/222 (49%), Gaps = 24/222 (10%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E E +++TF W+NS V+ + LY DL+D ++++L E + ++ KP
Sbjct: 38 EREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLS----GERLPKPTKG 93
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVL- 510
++ + LEN + A++ K + L +G D+ DGN LTL L+W ++ R+ + +
Sbjct: 94 RMRIHC--LENVDKALQFLKEQ-RVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDIS 150
Query: 511 ---EDLGDGQKANDDIIVNWVNRTLSEAG-KSTSIQSFKDKTISSSLAVVDLIDAIQPGC 566
ED + + A D +++ W + AG + +I +F + +A LI +P
Sbjct: 151 VETEDNKEKKSAKDALLL-WCQ--MKTAGYPNVNIHNF-TTSWRDGMAFNALIHKHRPDL 206
Query: 567 INYDLVKSGNLTEDDKHNNAKYAVSMA-RRIGARVYALPEDL 607
I++D +K N H N + A ++A + +G PED+
Sbjct: 207 IDFDKLKKSN-----AHYNLQNAFNLAEQHLGLTKLLDPEDI 243
Score = 56.2 bits (134), Expect = 9e-08
Identities = 55/242 (22%), Positives = 105/242 (43%), Gaps = 39/242 (16%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K F W+N H+ ++ DL+ + DG +L K++ + + + +
Sbjct: 43 QKKTFTKWVNS---------HLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKG 93
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
+ ++ EN++ AL H+ N+G+ D+ G L LGL+W II DI
Sbjct: 94 RMRIHCL---ENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDIS 150
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKIN--NFSADIKDSKAY 302
+ ET + K S ++ LL W ++ +G+ +N NF+ +D A+
Sbjct: 151 V-------------ETEDNKEKKSAKDALLLWC--QMKTAGYPNVNIHNFTTSWRDGMAF 195
Query: 303 FHLLNQIAPKGQKEGEPRIDIN-MSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSG 361
L+++ P ID + + N +L+ A ++ +Q LG + + P D+
Sbjct: 196 NALIHKHRP-------DLIDFDKLKKSNAHYNLQNAFNLAEQ--HLGLTKLLDPEDISVD 246
Query: 362 NP 363
+P
Sbjct: 247 HP 248
>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
sapiens]
Length = 2364
Score = 63.5 bits (153), Expect = 5e-10
Identities = 59/222 (26%), Positives = 109/222 (49%), Gaps = 24/222 (10%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E E +++TF W+NS V+ + LY DL+D ++++L E + ++ KP
Sbjct: 51 EREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLS----GERLPKPTKG 106
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVL- 510
++ + LEN + A++ K + L +G D+ DGN LTL L+W ++ R+ + +
Sbjct: 107 RMRIHC--LENVDKALQFLKEQ-RVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDIS 163
Query: 511 ---EDLGDGQKANDDIIVNWVNRTLSEAG-KSTSIQSFKDKTISSSLAVVDLIDAIQPGC 566
ED + + A D +++ W + AG + +I +F + +A LI +P
Sbjct: 164 VETEDNKEKKSAKDALLL-WCQ--MKTAGYPNVNIHNF-TTSWRDGMAFNALIHKHRPDL 219
Query: 567 INYDLVKSGNLTEDDKHNNAKYAVSMA-RRIGARVYALPEDL 607
I++D +K N H N + A ++A + +G PED+
Sbjct: 220 IDFDKLKKSN-----AHYNLQNAFNLAEQHLGLTKLLDPEDI 256
Score = 56.2 bits (134), Expect = 9e-08
Identities = 55/242 (22%), Positives = 105/242 (43%), Gaps = 39/242 (16%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K F W+N H+ ++ DL+ + DG +L K++ + + + +
Sbjct: 56 QKKTFTKWVNS---------HLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKG 106
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
+ ++ EN++ AL H+ N+G+ D+ G L LGL+W II DI
Sbjct: 107 RMRIHCL---ENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDIS 163
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKIN--NFSADIKDSKAY 302
+ ET + K S ++ LL W ++ +G+ +N NF+ +D A+
Sbjct: 164 V-------------ETEDNKEKKSAKDALLLWC--QMKTAGYPNVNIHNFTTSWRDGMAF 208
Query: 303 FHLLNQIAPKGQKEGEPRIDIN-MSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSG 361
L+++ P ID + + N +L+ A ++ +Q LG + + P D+
Sbjct: 209 NALIHKHRP-------DLIDFDKLKKSNAHYNLQNAFNLAEQ--HLGLTKLLDPEDISVD 259
Query: 362 NP 363
+P
Sbjct: 260 HP 261
>gi|67782321 spectrin beta isoform a [Homo sapiens]
Length = 2328
Score = 62.0 bits (149), Expect = 2e-09
Identities = 59/228 (25%), Positives = 105/228 (46%), Gaps = 26/228 (11%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E E +++TF W+NS V+ + LY DL+D ++++L E + + + KP
Sbjct: 51 EREVVQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIKLLEVLSGEM----LPKPTKG 106
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLN--- 508
K+ + LEN + A++ K + L +G D+ DGN L L L+W ++ R+ +
Sbjct: 107 KMRIHC--LENVDKALQFLKEQ-RVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIV 163
Query: 509 VLEDLGDGQKANDDIIVNWVNRTLS---EAGKSTSIQSFKDKTISSSLAVVDLIDAIQPG 565
V G ++ D ++ W + + S+KD LA LI +P
Sbjct: 164 VQTQEGRETRSAKDALLLWCQMKTAGYPHVNVTNFTSSWKD-----GLAFNALIHKHRPD 218
Query: 566 CINYDLVKSGNLTEDDKHNNAKYAVSMA-RRIGARVYALPEDLVEVKP 612
I++D +K N +N ++A ++A R++G PED+ P
Sbjct: 219 LIDFDKLKDSN-----ARHNLEHAFNVAERQLGIIPLLDPEDVFTENP 261
Score = 60.8 bits (146), Expect = 4e-09
Identities = 59/242 (24%), Positives = 108/242 (44%), Gaps = 39/242 (16%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K F W+N H+ ++ DL+K + DG +L K++ + + + +
Sbjct: 56 QKKTFTKWVNS---------HLARVSCRITDLYKDLRDGRMLIKLLEVLSGEMLPKPTKG 106
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
K ++ EN++ AL H+ N+G+ D+ G LVLGL+W II DI
Sbjct: 107 KMRIHCL---ENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIV 163
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKIN--NFSADIKDSKAY 302
+ +T E S ++ LL W ++ +G+ +N NF++ KD A+
Sbjct: 164 V-------------QTQEGRETRSAKDALLLWC--QMKTAGYPHVNVTNFTSSWKDGLAF 208
Query: 303 FHLLNQIAPKGQKEGEPRIDIN-MSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSG 361
L+++ P ID + + N +L+ A ++ ++ +LG + P DV +
Sbjct: 209 NALIHKHRP-------DLIDFDKLKDSNARHNLEHAFNVAER--QLGIIPLLDPEDVFTE 259
Query: 362 NP 363
NP
Sbjct: 260 NP 261
>gi|67782319 spectrin beta isoform b [Homo sapiens]
Length = 2137
Score = 62.0 bits (149), Expect = 2e-09
Identities = 59/228 (25%), Positives = 105/228 (46%), Gaps = 26/228 (11%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E E +++TF W+NS V+ + LY DL+D ++++L E + + + KP
Sbjct: 51 EREVVQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIKLLEVLSGEM----LPKPTKG 106
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLN--- 508
K+ + LEN + A++ K + L +G D+ DGN L L L+W ++ R+ +
Sbjct: 107 KMRIHC--LENVDKALQFLKEQ-RVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIV 163
Query: 509 VLEDLGDGQKANDDIIVNWVNRTLS---EAGKSTSIQSFKDKTISSSLAVVDLIDAIQPG 565
V G ++ D ++ W + + S+KD LA LI +P
Sbjct: 164 VQTQEGRETRSAKDALLLWCQMKTAGYPHVNVTNFTSSWKD-----GLAFNALIHKHRPD 218
Query: 566 CINYDLVKSGNLTEDDKHNNAKYAVSMA-RRIGARVYALPEDLVEVKP 612
I++D +K N +N ++A ++A R++G PED+ P
Sbjct: 219 LIDFDKLKDSN-----ARHNLEHAFNVAERQLGIIPLLDPEDVFTENP 261
Score = 60.8 bits (146), Expect = 4e-09
Identities = 59/242 (24%), Positives = 108/242 (44%), Gaps = 39/242 (16%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K F W+N H+ ++ DL+K + DG +L K++ + + + +
Sbjct: 56 QKKTFTKWVNS---------HLARVSCRITDLYKDLRDGRMLIKLLEVLSGEMLPKPTKG 106
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
K ++ EN++ AL H+ N+G+ D+ G LVLGL+W II DI
Sbjct: 107 KMRIHCL---ENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIV 163
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKIN--NFSADIKDSKAY 302
+ +T E S ++ LL W ++ +G+ +N NF++ KD A+
Sbjct: 164 V-------------QTQEGRETRSAKDALLLWC--QMKTAGYPHVNVTNFTSSWKDGLAF 208
Query: 303 FHLLNQIAPKGQKEGEPRIDIN-MSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSG 361
L+++ P ID + + N +L+ A ++ ++ +LG + P DV +
Sbjct: 209 NALIHKHRP-------DLIDFDKLKDSNARHNLEHAFNVAER--QLGIIPLLDPEDVFTE 259
Query: 362 NP 363
NP
Sbjct: 260 NP 261
>gi|169218211 PREDICTED: similar to plectin 1, partial [Homo
sapiens]
Length = 1369
Score = 61.6 bits (148), Expect = 2e-09
Identities = 60/266 (22%), Positives = 121/266 (45%), Gaps = 42/266 (15%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K W+NK H+I + DL++ + DG L ++ + D++
Sbjct: 177 QKKTSTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPR---- 223
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
+K F +N+ +AL+ +VNI +D+ G P L LGL+W II +DI+
Sbjct: 224 EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 283
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFH 304
+S G++ + ++ +E LL W+ +E + +NF++ +D + +
Sbjct: 284 VS-----------GQSED----MTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA 328
Query: 305 LLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADK-LGCRQFVTPADVVSGNP 363
++++ P + I+M+ +L+ + A++ LG + + P DV P
Sbjct: 329 IIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQP 379
Query: 364 --KLNLAFVANLFNKYPALTKPENQD 387
K + +V++L++ P + P+ QD
Sbjct: 380 DEKSIITYVSSLYDAMPRV--PDVQD 403
Score = 50.1 bits (118), Expect = 6e-06
Identities = 32/126 (25%), Positives = 60/126 (47%), Gaps = 10/126 (7%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E + +++T W+N + H++ LY DL+D ++ L E + + P
Sbjct: 172 ERDRVQKKTSTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSG-------DSLPRE 224
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLE 511
K KL+N A++ +H + LV I D+ DGN LTL L+W ++ + ++ ++
Sbjct: 225 KGRMRFHKLQNVQIALDYLRH-RQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 283
Query: 512 DLGDGQ 517
G +
Sbjct: 284 VSGQSE 289
>gi|110611228 utrophin [Homo sapiens]
Length = 3433
Score = 61.6 bits (148), Expect = 2e-09
Identities = 41/139 (29%), Positives = 72/139 (51%), Gaps = 14/139 (10%)
Query: 399 EERTFRNWMN---SLGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGA 455
+++TF W+N S P +N ++ DL+D +L L E + P +
Sbjct: 33 QKKTFTKWINARFSKSGKPPINDMFTDLKDGRKLLDLLEGLTG-------TSLPKERGST 85
Query: 456 NMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTL-NVLED-L 513
+ L N N +++ H LV IGG D+ DGN LTL L+W ++ + + +V++D +
Sbjct: 86 RVHALNNVNRVLQV-LHQNNVELVNIGGTDIVDGNHKLTLGLLWSIILHWQVKDVMKDVM 144
Query: 514 GDGQKANDD-IIVNWVNRT 531
D Q+ N + I+++WV +T
Sbjct: 145 SDLQQTNSEKILLSWVRQT 163
Score = 46.6 bits (109), Expect = 7e-05
Identities = 58/276 (21%), Positives = 103/276 (37%), Gaps = 39/276 (14%)
Query: 108 GTSELSS--EGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIV 165
G +E S + +++ +K F WIN P +D+F + DG
Sbjct: 14 GQNEFSDIIKSRSDEHNDVQKKTFTKWINARFSKSG--------KPPINDMFTDLKDGRK 65
Query: 166 LCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPH 225
L ++ ++ + ++ T N+N L +VNIG D+ G
Sbjct: 66 LLDLLEGLTGTSLPK----ERGSTRVHALNNVNRVLQVLHQNNVELVNIGGTDIVDGNHK 121
Query: 226 LVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSG 285
L LGLLW II D+ ++D + +L + + E++LL W
Sbjct: 122 LTLGLLWSIILHWQVKDV-----------MKD--VMSDLQQTNSEKILLSWVRQTTRPYS 168
Query: 286 WQKINNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQAD 345
+ NF+ D A+ +L++ P + + ++R E +A
Sbjct: 169 QVNVLNFTTSWTDGLAFNAVLHRHKPD---------LFSWDKVVKMSPIERLEHAFSKAQ 219
Query: 346 K-LGCRQFVTPADVVSGNP--KLNLAFVANLFNKYP 378
LG + + P DV P K + ++ +LF P
Sbjct: 220 TYLGIEKLLDPEDVAVQLPDKKSIIMYLTSLFEVLP 255
>gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]
Length = 2390
Score = 60.8 bits (146), Expect = 4e-09
Identities = 63/237 (26%), Positives = 115/237 (48%), Gaps = 26/237 (10%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYP 451
E E +++TF W+NS V V LY+DL+D +L+L E + + + KP
Sbjct: 54 EREAVQKKTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEI----LPKPTKG 109
Query: 452 KLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVL- 510
++ + LEN + A++ K K L +G D+ DGN LTL LVW ++ R+ + +
Sbjct: 110 RMRIHC--LENVDKALQFLKEQ-KVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDIS 166
Query: 511 ---EDLGDGQKANDDIIVNWVNRTLSEAG-KSTSIQSFKDKTISSSLAVVDLIDAIQPGC 566
ED + + A D +++ W + AG + ++ +F + LA ++ +P
Sbjct: 167 VETEDNKEKKSAKDALLL-WCQ--MKTAGYPNVNVHNF-TTSWRDGLAFNAIVHKHRPDL 222
Query: 567 INYDLVKSGNLTEDDKHNNAKYAVSMA-RRIGARVYALPEDLVEVKP--KMVMTVFA 620
++++ +K N H N + A ++A + +G PED+ +P K ++T A
Sbjct: 223 LDFESLKKCN-----AHYNLQNAFNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVA 274
Score = 51.6 bits (122), Expect = 2e-06
Identities = 55/258 (21%), Positives = 111/258 (43%), Gaps = 41/258 (15%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K F W+N H+ + DL+ + DG L +++ + + + +
Sbjct: 59 QKKTFTKWVNS---------HLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKG 109
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
+ ++ EN++ AL H+ N+G+ D+ G L LGL+W II DI
Sbjct: 110 RMRIHCL---ENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDIS 166
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKIN--NFSADIKDSKAY 302
+ ET + K S ++ LL W ++ +G+ +N NF+ +D A+
Sbjct: 167 V-------------ETEDNKEKKSAKDALLLWC--QMKTAGYPNVNVHNFTTSWRDGLAF 211
Query: 303 FHLLNQIAPKGQKEGEPRIDI-NMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSG 361
++++ P +D ++ N +L+ A ++ ++ +LG + + P DV
Sbjct: 212 NAIVHKHRP-------DLLDFESLKKCNAHYNLQNAFNLAEK--ELGLTKLLDPEDVNVD 262
Query: 362 NP--KLNLAFVANLFNKY 377
P K + +VA ++ +
Sbjct: 263 QPDEKSIITYVATYYHYF 280
>gi|33188445 microfilament and actin filament cross-linker protein
isoform a [Homo sapiens]
Length = 5430
Score = 59.7 bits (143), Expect = 8e-09
Identities = 58/256 (22%), Positives = 110/256 (42%), Gaps = 39/256 (15%)
Query: 125 EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
+K F W+NK H++ + + +DL++ + DG L ++ + +
Sbjct: 80 QKKTFTKWVNK---------HLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPR---- 126
Query: 185 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 244
+K F +N+ +AL+ +VNI +D+ G P L LGL+W II +DI
Sbjct: 127 EKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIY 186
Query: 245 LSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFH 304
+S GE+ + +S +E LL W K NFS+ D K +
Sbjct: 187 IS-----------GESGD----MSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNA 231
Query: 305 LLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFV--TPADVVSGN 362
L+++ P ++M + + E + A++LG + + DV S +
Sbjct: 232 LIHRYRPD---------LVDMERVQIQSNRENLEQAFEVAERLGVTRLLDAEDVDVPSPD 282
Query: 363 PKLNLAFVANLFNKYP 378
K + +V+++++ +P
Sbjct: 283 EKSVITYVSSIYDAFP 298
Score = 58.5 bits (140), Expect = 2e-08
Identities = 59/235 (25%), Positives = 106/235 (45%), Gaps = 32/235 (13%)
Query: 394 EGETREERTFRNWMNS--LGVNPHVNHLYADLQDA---LVILQLYERIKVPVDWSKVNKP 448
E + +++TF W+N + V H+N LY DL+D + +L++ IK+P + ++
Sbjct: 75 ERDRVQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPREKGRMR-- 132
Query: 449 PYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLN 508
+L+N A++ K + LV I D+ DGN LTL L+W ++ + ++
Sbjct: 133 --------FHRLQNVQIALDFLKQ-RQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQIS 183
Query: 509 VLEDLGD-GQKANDDIIVNWVNR-TLSEAG-KSTSIQS-FKDKTISSSLAVVDLIDAIQP 564
+ G+ G + + ++ W + T G K T+ S + D + ++ LI +P
Sbjct: 184 DIYISGESGDMSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNA-----LIHRYRP 238
Query: 565 GCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKP--KMVMT 617
DLV + N + A +A R+G ED+ P K V+T
Sbjct: 239 -----DLVDMERVQIQSNRENLEQAFEVAERLGVTRLLDAEDVDVPSPDEKSVIT 288
Score = 29.6 bits (65), Expect = 8.8
Identities = 19/77 (24%), Positives = 40/77 (51%), Gaps = 4/77 (5%)
Query: 244 ELSRNEALAALLRDGETLEE--LMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKA 301
+L + + ++D E L + +KLS EE++L A+ + W + ++ +D+KD +
Sbjct: 1155 KLKTVDVIVRSIQDAELLVKGYEIKLSQEEVVL--ADLSALEAHWSTLRHWLSDVKDKNS 1212
Query: 302 YFHLLNQIAPKGQKEGE 318
F +L++ K + E
Sbjct: 1213 VFSVLDEEIAKAKVVAE 1229
>gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens]
Length = 3639
Score = 57.8 bits (138), Expect = 3e-08
Identities = 61/234 (26%), Positives = 113/234 (48%), Gaps = 32/234 (13%)
Query: 399 EERTFRNWMNSL------GVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYPK 452
+E+TF W+N++ G+ + +LY +L D + +L+L E I S PP +
Sbjct: 21 QEKTFTKWINNVFQCGQAGIK--IRNLYTELADGIHLLRLLELI------SGEALPPPSR 72
Query: 453 LGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVL-- 510
+ LEN + A+ + AK + IG +++ DG+QTL L L+W ++ R+ ++ +
Sbjct: 73 GRLRVHFLENSSRALAFLR--AKVPVPLIGPENIVDGDQTLILGLIWVIILRFQISHISL 130
Query: 511 --EDLGDGQK--ANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGC 566
E+ G + + ++ W R + + + +I F ++ S L LI A +P
Sbjct: 131 DKEEFGASAALLSTKEALLVWCQRK-TASYTNVNITDF-SRSWSDGLGFNALIHAHRP-- 186
Query: 567 INYDLVKSGNLTEDDKHNNAKYAVSMA-RRIGARVYALPEDLVEVKP--KMVMT 617
DL+ G+L D +N +A +A + +G PED+ +P + +MT
Sbjct: 187 ---DLLDYGSLRPDRPLHNLAFAFLVAEQELGIAQLLDPEDVAAAQPDERSIMT 237
Score = 43.9 bits (102), Expect = 5e-04
Identities = 59/248 (23%), Positives = 95/248 (38%), Gaps = 33/248 (13%)
Query: 118 QHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDT 177
Q + + ++ F WIN + C +L+ + DGI L +++ L +
Sbjct: 14 QARHMQMQEKTFTKWINNVFQ----CGQA---GIKIRNLYTELADGIHLLRLLELISGEA 66
Query: 178 IDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKI 237
+ + + ++ F+ + LA A V IG E++ G L+LGL+W II
Sbjct: 67 LPPPSRGRLRVH-FLENSSRALAFLRAKV---PVPLIGPENIVDGDQTLILGLIWVIILR 122
Query: 238 GLFADIELSRNE--ALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSAD 295
+ I L + E A AAL LS +E LL W + I +FS
Sbjct: 123 FQISHISLDKEEFGASAAL------------LSTKEALLVWCQRKTASYTNVNITDFSRS 170
Query: 296 IKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTP 355
D + L++ P G R D + A + L +LG Q + P
Sbjct: 171 WSDGLGFNALIHAHRPDLLDYGSLRPDRPLHNL--------AFAFLVAEQELGIAQLLDP 222
Query: 356 ADVVSGNP 363
DV + P
Sbjct: 223 EDVAAAQP 230
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,971,858
Number of Sequences: 37866
Number of extensions: 999961
Number of successful extensions: 2629
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 88
Number of HSP's successfully gapped in prelim test: 100
Number of HSP's that attempted gapping in prelim test: 2237
Number of HSP's gapped (non-prelim): 327
length of query: 630
length of database: 18,247,518
effective HSP length: 108
effective length of query: 522
effective length of database: 14,157,990
effective search space: 7390470780
effective search space used: 7390470780
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.