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Search of human proteins with 7524361
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7524361 paired box 8 isoform PAX8B [Homo sapiens]
(387 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7524361 paired box 8 isoform PAX8B [Homo sapiens] 795 0.0
gi|5803117 paired box 8 isoform PAX8A [Homo sapiens] 699 0.0
gi|7524363 paired box 8 isoform PAX8C [Homo sapiens] 614 e-176
gi|7524365 paired box 8 isoform PAX8D [Homo sapiens] 533 e-152
gi|7669542 paired box 8 isoform PAX8E [Homo sapiens] 532 e-151
gi|34878701 paired box protein 2 isoform b [Homo sapiens] 494 e-140
gi|34878699 paired box protein 2 isoform a [Homo sapiens] 484 e-137
gi|34878716 paired box protein 2 isoform d [Homo sapiens] 474 e-134
gi|34878703 paired box protein 2 isoform e [Homo sapiens] 464 e-131
gi|9951920 paired box 5 [Homo sapiens] 456 e-128
gi|34878709 paired box protein 2 isoform c [Homo sapiens] 433 e-121
gi|189083681 paired box gene 6 isoform a [Homo sapiens] 222 4e-58
gi|4505615 paired box gene 6 isoform a [Homo sapiens] 222 4e-58
gi|4580424 paired box gene 6 isoform b [Homo sapiens] 213 3e-55
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 212 4e-55
gi|7524359 paired box 7 isoform 2 [Homo sapiens] 211 9e-55
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 207 1e-53
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 207 1e-53
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 207 1e-53
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 207 1e-53
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 207 1e-53
gi|4505619 paired box 7 isoform 1 [Homo sapiens] 206 3e-53
gi|207029223 paired box 7 isoform 3 [Homo sapiens] 206 3e-53
gi|197276661 paired box 1 [Homo sapiens] 194 9e-50
gi|7242167 paired box 9 [Homo sapiens] 194 1e-49
gi|7524356 paired box 3 isoform PAX3b [Homo sapiens] 191 1e-48
gi|6654638 paired box 3 isoform PAX3a [Homo sapiens] 191 1e-48
gi|170784824 paired box 4 [Homo sapiens] 164 1e-40
gi|55743092 aristaless-like homeobox 4 [Homo sapiens] 41 0.002
gi|139394646 iroquois homeobox protein 5 [Homo sapiens] 39 0.006
>gi|7524361 paired box 8 isoform PAX8B [Homo sapiens]
Length = 387
Score = 795 bits (2053), Expect = 0.0
Identities = 387/387 (100%), Positives = 387/387 (100%)
Query: 1 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 60
MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
Sbjct: 1 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 60
Query: 61 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 120
ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
Sbjct: 61 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 120
Query: 121 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 180
TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
Sbjct: 121 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 180
Query: 181 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF 240
SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
Sbjct: 181 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF 240
Query: 241 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAG 300
ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAG
Sbjct: 241 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAG 300
Query: 301 REMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNSS 360
REMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNSS
Sbjct: 301 REMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNSS 360
Query: 361 LLSSPYYYSSTSRPSAPPTTATAFDHL 387
LLSSPYYYSSTSRPSAPPTTATAFDHL
Sbjct: 361 LLSSPYYYSSTSRPSAPPTTATAFDHL 387
>gi|5803117 paired box 8 isoform PAX8A [Homo sapiens]
Length = 450
Score = 699 bits (1803), Expect = 0.0
Identities = 362/450 (80%), Positives = 370/450 (82%), Gaps = 63/450 (14%)
Query: 1 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 60
MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
Sbjct: 1 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 60
Query: 61 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 120
ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
Sbjct: 61 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 120
Query: 121 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 180
TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
Sbjct: 121 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 180
Query: 181 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF 240
SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
Sbjct: 181 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF 240
Query: 241 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVA- 299
ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVA
Sbjct: 241 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAD 300
Query: 300 ------------------------------GREMVGPTLPGYP--PHIPT-----SGQGS 322
+ VG +P + PH + +GQ
Sbjct: 301 PHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHAASVYGQFTGQAL 360
Query: 323 YASSAIAG---------------------MVAG----SEYSGNAYGHTPYSSYSEAWRFP 357
+ + G +AG SEYSGNAYGHTPYSSYSEAWRFP
Sbjct: 361 LSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFP 420
Query: 358 NSSLLSSPYYYSSTSRPSAPPTTATAFDHL 387
NSSLLSSPYYYSSTSRPSAPPTTATAFDHL
Sbjct: 421 NSSLLSSPYYYSSTSRPSAPPTTATAFDHL 450
>gi|7524363 paired box 8 isoform PAX8C [Homo sapiens]
Length = 398
Score = 614 bits (1584), Expect = e-176
Identities = 303/318 (95%), Positives = 306/318 (96%), Gaps = 2/318 (0%)
Query: 1 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 60
MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
Sbjct: 1 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 60
Query: 61 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 120
ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
Sbjct: 61 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 120
Query: 121 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 180
TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
Sbjct: 121 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 180
Query: 181 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF 240
SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
Sbjct: 181 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF 240
Query: 241 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAG 300
ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVA
Sbjct: 241 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAA 300
Query: 301 RE--MVGPTLPGYPPHIP 316
+ + PG P +P
Sbjct: 301 PPFWICSKSAPGSRPSMP 318
>gi|7524365 paired box 8 isoform PAX8D [Homo sapiens]
Length = 321
Score = 533 bits (1374), Expect = e-152
Identities = 260/260 (100%), Positives = 260/260 (100%)
Query: 1 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 60
MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
Sbjct: 1 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 60
Query: 61 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 120
ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
Sbjct: 61 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 120
Query: 121 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 180
TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
Sbjct: 121 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 180
Query: 181 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF 240
SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
Sbjct: 181 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF 240
Query: 241 ERQHYPEAYASPSHTKGEQG 260
ERQHYPEAYASPSHTKGEQG
Sbjct: 241 ERQHYPEAYASPSHTKGEQG 260
>gi|7669542 paired box 8 isoform PAX8E [Homo sapiens]
Length = 287
Score = 532 bits (1370), Expect = e-151
Identities = 261/270 (96%), Positives = 264/270 (97%)
Query: 1 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 60
MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
Sbjct: 1 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 60
Query: 61 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 120
ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
Sbjct: 61 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 120
Query: 121 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 180
TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
Sbjct: 121 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 180
Query: 181 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF 240
SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
Sbjct: 181 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF 240
Query: 241 ERQHYPEAYASPSHTKGEQGLYPLPLLNST 270
ERQHYPEAYASPSHTKGEQ + L + +T
Sbjct: 241 ERQHYPEAYASPSHTKGEQEVNTLAMPMAT 270
>gi|34878701 paired box protein 2 isoform b [Homo sapiens]
Length = 393
Score = 494 bits (1273), Expect = e-140
Identities = 249/386 (64%), Positives = 294/386 (76%), Gaps = 5/386 (1%)
Query: 2 PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61
P +++ GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 9 PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
Query: 62 LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121
LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 69 LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
Query: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181
VPSVSSINRIIRTKVQQPF+ P T +PGHT++PS+A P S +D +GS YS
Sbjct: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
Query: 182 INGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPFE 241
ING+LGI + +KRK D+ + + DSQS RKHLR D F+Q LE L+ FE
Sbjct: 187 INGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFE 246
Query: 242 RQHYPEAYASPSHTKGEQGL-YPLPLLNSTLDDGKATLTPSNTP-LGRNLSTHQTYPVVA 299
R YP+ + + H K EQG Y LP L LD+ K++L+ S P LG N+S QTYPVV
Sbjct: 247 RPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVT 306
Query: 300 GREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNS 359
GR+M TLPGYPPH+P +GQGSY +S +AGMV GSE+SGN Y H Y++Y+EAWRF N
Sbjct: 307 GRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNP 366
Query: 360 SLLSSPYYYSSTSRPSAPPTTATAFD 385
+LLSSPYYYS+ R SAP A A+D
Sbjct: 367 ALLSSPYYYSAAPR-SAPAAAAAAYD 391
>gi|34878699 paired box protein 2 isoform a [Homo sapiens]
Length = 416
Score = 484 bits (1246), Expect = e-137
Identities = 251/409 (61%), Positives = 297/409 (72%), Gaps = 28/409 (6%)
Query: 2 PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61
P +++ GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 9 PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
Query: 62 LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121
LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 69 LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
Query: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181
VPSVSSINRIIRTKVQQPF+ P T +PGHT++PS+A P S +D +GS YS
Sbjct: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
Query: 182 INGLLGIAQPGSDKRKMDDSD--------------------QDSCRLSI---DSQSSSSG 218
ING+LGI + +KRK D+ + +D S+ DSQS
Sbjct: 187 INGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS 246
Query: 219 PRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQGL-YPLPLLNSTLDDGKAT 277
RKHLR D F+Q LE L+ FER YP+ + + H K EQG Y LP L LD+ K++
Sbjct: 247 LRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSS 306
Query: 278 LTPSNTP-LGRNLSTHQTYPVVAGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSE 336
L+ S P LG N+S QTYPVV GR+M TLPGYPPH+P +GQGSY +S +AGMV GSE
Sbjct: 307 LSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSE 366
Query: 337 YSGNAYGHTPYSSYSEAWRFPNSSLLSSPYYYSSTSRPSAPPTTATAFD 385
+SGN Y H Y++Y+EAWRF N +LLSSPYYYS+ R SAP A A+D
Sbjct: 367 FSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPR-SAPAAAAAAYD 414
>gi|34878716 paired box protein 2 isoform d [Homo sapiens]
Length = 408
Score = 474 bits (1221), Expect = e-134
Identities = 244/391 (62%), Positives = 290/391 (74%), Gaps = 10/391 (2%)
Query: 2 PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61
P +++ GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 9 PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
Query: 62 LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121
LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 69 LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
Query: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181
VPSVSSINRIIRTKVQQPF+ P T +PGHT++PS+A P S +D +GS YS
Sbjct: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
Query: 182 INGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPFE 241
ING+LGI + +KRK D+ + + DSQS RKHLR D F+Q LE L+ FE
Sbjct: 187 INGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFE 246
Query: 242 RQHYPEAYASPSHTKGEQG-LYPLPLLNSTLDDGKATLTPSNTP-LGRNLSTHQTYPVVA 299
R YP+ + + H K EQG Y LP L LD+ K++L+ S P LG N+S QTYPVV
Sbjct: 247 RPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVT 306
Query: 300 GREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNS 359
GR+M TLPGYPPH+P +GQGSY +S +AGMV GSE+SGN Y H Y++Y+EAWRF N
Sbjct: 307 GRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNP 366
Query: 360 SLLSSPYYYSSTSRPSAP-PTTATAF--DHL 387
+LL P P P P TAT++ DH+
Sbjct: 367 ALLMPP---PGPPLPLLPLPMTATSYRGDHI 394
>gi|34878703 paired box protein 2 isoform e [Homo sapiens]
Length = 431
Score = 464 bits (1194), Expect = e-131
Identities = 246/414 (59%), Positives = 293/414 (70%), Gaps = 33/414 (7%)
Query: 2 PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61
P +++ GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 9 PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
Query: 62 LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121
LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 69 LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
Query: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181
VPSVSSINRIIRTKVQQPF+ P T +PGHT++PS+A P S +D +GS YS
Sbjct: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
Query: 182 INGLLGIAQPGSDKRKMDDSD--------------------QDSCRLSI---DSQSSSSG 218
ING+LGI + +KRK D+ + +D S+ DSQS
Sbjct: 187 INGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDS 246
Query: 219 PRKHLRTDAFSQHHLEPLECPFERQHYPEAYASPSHTKGEQG-LYPLPLLNSTLDDGKAT 277
RKHLR D F+Q LE L+ FER YP+ + + H K EQG Y LP L LD+ K++
Sbjct: 247 LRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSS 306
Query: 278 LTPSNTP-LGRNLSTHQTYPVVAGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSE 336
L+ S P LG N+S QTYPVV GR+M TLPGYPPH+P +GQGSY +S +AGMV GSE
Sbjct: 307 LSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSE 366
Query: 337 YSGNAYGHTPYSSYSEAWRFPNSSLLSSPYYYSSTSRPSAP-PTTATAF--DHL 387
+SGN Y H Y++Y+EAWRF N +LL P P P P TAT++ DH+
Sbjct: 367 FSGNPYSHPQYTAYNEAWRFSNPALLMPP---PGPPLPLLPLPMTATSYRGDHI 417
>gi|9951920 paired box 5 [Homo sapiens]
Length = 391
Score = 456 bits (1172), Expect = e-128
Identities = 232/384 (60%), Positives = 283/384 (73%), Gaps = 13/384 (3%)
Query: 7 RSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYY 66
R+GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKILGRYY
Sbjct: 14 RTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYY 73
Query: 67 ETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVS 126
ETGSI+PGVIGGSKPKVATPKVVEKI +YKRQNPTMFAWEIRDRLLAE VCDNDTVPSVS
Sbjct: 74 ETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVS 133
Query: 127 SINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLL 186
SINRIIRTKVQQP N P+ + H+++ + +VT S +DS GS+YSI+G+L
Sbjct: 134 SINRIIRTKVQQPPNQPVP--------ASSHSIVSTGSVTQVSSVSTDSAGSSYSISGIL 185
Query: 187 GIAQPGSD--KRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPFERQH 244
GI P +D KRK D+ Q+S + S RK +R D F+Q LE L+ FERQH
Sbjct: 186 GITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQH 245
Query: 245 YPEAYASPSHTKGEQ--GLYPLPLLNSTLDDGKATL-TPSNTPLGRNLSTHQTYPVVAGR 301
Y + + + K EQ + L LDD KA L +P+ +G ++ Q+YP+V GR
Sbjct: 246 YSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGR 305
Query: 302 EMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNSSL 361
++ TLPGYPPH+P +GQGSY++ + GMV GSE+SG+ Y H YSSY+++WRFPN L
Sbjct: 306 DLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRFPNPGL 365
Query: 362 LSSPYYYSSTSRPSAPPTTATAFD 385
L SPYYYS+ +R +APP ATA+D
Sbjct: 366 LGSPYYYSAAARGAAPPAAATAYD 389
>gi|34878709 paired box protein 2 isoform c [Homo sapiens]
Length = 396
Score = 433 bits (1114), Expect = e-121
Identities = 229/384 (59%), Positives = 272/384 (70%), Gaps = 22/384 (5%)
Query: 2 PHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKI 61
P +++ GHGG+NQLGG FVNGRPLP+VVRQRIV+LAHQGVRPCDISRQLRVSHGCVSKI
Sbjct: 9 PFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI 68
Query: 62 LGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDT 121
LGRYYETGSI+PGVIGGSKPKVATPKVV+KI +YKRQNPTMFAWEIRDRLLAEG+CDNDT
Sbjct: 69 LGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDT 128
Query: 122 VPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYS 181
VPSVSSINRIIRTKVQQPF+ P T +PGHT++PS+A P S +D +GS YS
Sbjct: 129 VPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGS-YS 186
Query: 182 INGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPFE 241
ING+LGI + +KRK D+ + + DSQS RKHLR D F+Q LE L+ FE
Sbjct: 187 INGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFE 246
Query: 242 RQHYPEAYASPSHTKGEQG-LYPLPLLNSTLDDGKATLTPSNTP-LGRNLSTHQTYPVVA 299
R YP+ + + H K EQG Y LP L LD+ K++L+ S P LG N+S QTYPVV
Sbjct: 247 RPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVT 306
Query: 300 GREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNS 359
GR+M TLPGYPPH+P +GQGSY +S +AGMV EA P+S
Sbjct: 307 GRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMV------------------PEAAVGPSS 348
Query: 360 SLLSSPYYYSSTSRPSAPPTTATA 383
SL+S P + P PT A++
Sbjct: 349 SLMSKPGRKLAEVPPCVQPTGASS 372
>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 222 bits (566), Expect = 4e-58
Identities = 123/253 (48%), Positives = 156/253 (61%), Gaps = 22/253 (8%)
Query: 6 IRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRY 65
+++ H G+NQLGG FVNGRPLP+ RQ+IV+LAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 1 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
Query: 66 YETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSV 125
YETGSIRP IGGSKP+VATP+VV KI YKR+ P++FAWEIRDRLL+EGVC ND +PSV
Sbjct: 61 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
Query: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHT--------LIPSSAVTPPESPQSDSLG 177
SSINR++R + + D + G T P ++V P P D
Sbjct: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSV--PGQPTQDGCQ 178
Query: 178 STYSINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLE 237
G S +DSD+ RL + + + RT +F+Q +E LE
Sbjct: 179 QQEG-----GGENTNSISSNGEDSDEAQMRLQLKRKLQRN------RT-SFTQEQIEALE 226
Query: 238 CPFERQHYPEAYA 250
FER HYP+ +A
Sbjct: 227 KEFERTHYPDVFA 239
>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 222 bits (566), Expect = 4e-58
Identities = 123/253 (48%), Positives = 156/253 (61%), Gaps = 22/253 (8%)
Query: 6 IRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRY 65
+++ H G+NQLGG FVNGRPLP+ RQ+IV+LAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 1 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
Query: 66 YETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSV 125
YETGSIRP IGGSKP+VATP+VV KI YKR+ P++FAWEIRDRLL+EGVC ND +PSV
Sbjct: 61 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
Query: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHT--------LIPSSAVTPPESPQSDSLG 177
SSINR++R + + D + G T P ++V P P D
Sbjct: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSV--PGQPTQDGCQ 178
Query: 178 STYSINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLE 237
G S +DSD+ RL + + + RT +F+Q +E LE
Sbjct: 179 QQEG-----GGENTNSISSNGEDSDEAQMRLQLKRKLQRN------RT-SFTQEQIEALE 226
Query: 238 CPFERQHYPEAYA 250
FER HYP+ +A
Sbjct: 227 KEFERTHYPDVFA 239
>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
Length = 436
Score = 213 bits (541), Expect = 3e-55
Identities = 123/267 (46%), Positives = 156/267 (58%), Gaps = 36/267 (13%)
Query: 6 IRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLR------------- 52
+++ H G+NQLGG FVNGRPLP+ RQ+IV+LAH G RPCDISR L+
Sbjct: 1 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60
Query: 53 -VSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRL 111
VS+GCVSKILGRYYETGSIRP IGGSKP+VATP+VV KI YKR+ P++FAWEIRDRL
Sbjct: 61 NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120
Query: 112 LAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHT--------LIPSS 163
L+EGVC ND +PSVSSINR++R + + D + G T P +
Sbjct: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 180
Query: 164 AVTPPESPQSDSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHL 223
+V P P D G S +DSD+ RL + + +
Sbjct: 181 SV--PGQPTQDGCQQQEG-----GGENTNSISSNGEDSDEAQMRLQLKRKLQRN------ 227
Query: 224 RTDAFSQHHLEPLECPFERQHYPEAYA 250
RT +F+Q +E LE FER HYP+ +A
Sbjct: 228 RT-SFTQEQIEALEKEFERTHYPDVFA 253
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 212 bits (540), Expect = 4e-55
Identities = 120/242 (49%), Positives = 153/242 (63%), Gaps = 30/242 (12%)
Query: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 69 GSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSI 128
GSIRPG IGGSKPKV TP V +KI +YKR+NP MF+WEIRD+LL + VCD +TVPSVSSI
Sbjct: 94 GSIRPGAIGGSKPKVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSI 153
Query: 129 NRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGI 188
+RI+R+K G + + E+ +S+ + +SI+G+L
Sbjct: 154 SRILRSKF-------------------GKGEEEEADLERKEAEESEK-KAKHSIDGIL-- 191
Query: 189 AQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQHYPE 247
S++ SD+ S IDS+ RK R+ F+ LE LE FER HYP+
Sbjct: 192 ----SERASAPQSDEGS---DIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPD 244
Query: 248 AY 249
Y
Sbjct: 245 IY 246
>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
Length = 518
Score = 211 bits (537), Expect = 9e-55
Identities = 158/408 (38%), Positives = 199/408 (48%), Gaps = 84/408 (20%)
Query: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSS 127
GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSS 153
Query: 128 INRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLG 187
I+R++R K F + A K G + +SI+G+LG
Sbjct: 154 ISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGILG 191
Query: 188 IAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQHYP 246
DK D D ++S+ RK R+ F+ LE LE FER HYP
Sbjct: 192 ------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 240
Query: 247 EAYASP---------------------SHTKGEQGLYPLPLLNSTL-----DDGKATLTP 280
+ Y + + + G L N L G TL P
Sbjct: 241 DIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPP 300
Query: 281 SNTPLGRNLSTHQTYPVVAGREMVGPTLPGYPPHIP-TSGQGSYASSAIAGMVAGSEYSG 339
P TYP + G T+ P P T QG A++A A +
Sbjct: 301 YQLP-------DSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAA------DTS 347
Query: 340 NAYG-HTPYSSYSEAWRFPNS--------SLLSSPYYYSSTSRPSAPP 378
+AYG +SSYS+++ P + S SP S PSA P
Sbjct: 348 SAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVP 395
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 207 bits (528), Expect = 1e-53
Identities = 120/243 (49%), Positives = 153/243 (62%), Gaps = 31/243 (12%)
Query: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSS 127
GSIRPG IGGSKPK V TP V +KI +YKR+NP MF+WEIRD+LL + VCD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 128 INRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLG 187
I+RI+R+K G + + E+ +S+ + +SI+G+L
Sbjct: 154 ISRILRSKF-------------------GKGEEEEADLERKEAEESEK-KAKHSIDGIL- 192
Query: 188 IAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQHYP 246
S++ SD+ S IDS+ RK R+ F+ LE LE FER HYP
Sbjct: 193 -----SERASAPQSDEGS---DIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYP 244
Query: 247 EAY 249
+ Y
Sbjct: 245 DIY 247
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 207 bits (528), Expect = 1e-53
Identities = 120/243 (49%), Positives = 153/243 (62%), Gaps = 31/243 (12%)
Query: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSS 127
GSIRPG IGGSKPK V TP V +KI +YKR+NP MF+WEIRD+LL + VCD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 128 INRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLG 187
I+RI+R+K G + + E+ +S+ + +SI+G+L
Sbjct: 154 ISRILRSKF-------------------GKGEEEEADLERKEAEESEK-KAKHSIDGIL- 192
Query: 188 IAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQHYP 246
S++ SD+ S IDS+ RK R+ F+ LE LE FER HYP
Sbjct: 193 -----SERASAPQSDEGS---DIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYP 244
Query: 247 EAY 249
+ Y
Sbjct: 245 DIY 247
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 207 bits (528), Expect = 1e-53
Identities = 120/243 (49%), Positives = 153/243 (62%), Gaps = 31/243 (12%)
Query: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSS 127
GSIRPG IGGSKPK V TP V +KI +YKR+NP MF+WEIRD+LL + VCD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 128 INRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLG 187
I+RI+R+K G + + E+ +S+ + +SI+G+L
Sbjct: 154 ISRILRSKF-------------------GKGEEEEADLERKEAEESEK-KAKHSIDGIL- 192
Query: 188 IAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQHYP 246
S++ SD+ S IDS+ RK R+ F+ LE LE FER HYP
Sbjct: 193 -----SERASAPQSDEGS---DIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYP 244
Query: 247 EAY 249
+ Y
Sbjct: 245 DIY 247
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 207 bits (528), Expect = 1e-53
Identities = 120/243 (49%), Positives = 153/243 (62%), Gaps = 31/243 (12%)
Query: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSS 127
GSIRPG IGGSKPK V TP V +KI +YKR+NP MF+WEIRD+LL + VCD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 128 INRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLG 187
I+RI+R+K G + + E+ +S+ + +SI+G+L
Sbjct: 154 ISRILRSKF-------------------GKGEEEEADLERKEAEESEK-KAKHSIDGIL- 192
Query: 188 IAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQHYP 246
S++ SD+ S IDS+ RK R+ F+ LE LE FER HYP
Sbjct: 193 -----SERASAPQSDEGS---DIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYP 244
Query: 247 EAY 249
+ Y
Sbjct: 245 DIY 247
>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
Length = 479
Score = 207 bits (528), Expect = 1e-53
Identities = 120/243 (49%), Positives = 153/243 (62%), Gaps = 31/243 (12%)
Query: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSS 127
GSIRPG IGGSKPK V TP V +KI +YKR+NP MF+WEIRD+LL + VCD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 128 INRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLG 187
I+RI+R+K G + + E+ +S+ + +SI+G+L
Sbjct: 154 ISRILRSKF-------------------GKGEEEEADLERKEAEESEK-KAKHSIDGIL- 192
Query: 188 IAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQHYP 246
S++ SD+ S IDS+ RK R+ F+ LE LE FER HYP
Sbjct: 193 -----SERASAPQSDEGS---DIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYP 244
Query: 247 EAY 249
+ Y
Sbjct: 245 DIY 247
>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
Length = 520
Score = 206 bits (524), Expect = 3e-53
Identities = 158/410 (38%), Positives = 199/410 (48%), Gaps = 86/410 (20%)
Query: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPS--V 125
GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD TVPS V
Sbjct: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
Query: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGL 185
SSI+R++R K F + A K G + +SI+G+
Sbjct: 154 SSISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGI 191
Query: 186 LGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQH 244
LG DK D D ++S+ RK R+ F+ LE LE FER H
Sbjct: 192 LG------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
Query: 245 YPEAYASP---------------------SHTKGEQGLYPLPLLNSTL-----DDGKATL 278
YP+ Y + + + G L N L G TL
Sbjct: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
Query: 279 TPSNTPLGRNLSTHQTYPVVAGREMVGPTLPGYPPHIP-TSGQGSYASSAIAGMVAGSEY 337
P P TYP + G T+ P P T QG A++A A
Sbjct: 301 PPYQLP-------DSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAA------D 347
Query: 338 SGNAYG-HTPYSSYSEAWRFPNS--------SLLSSPYYYSSTSRPSAPP 378
+ +AYG +SSYS+++ P + S SP S PSA P
Sbjct: 348 TSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVP 397
>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
Length = 505
Score = 206 bits (524), Expect = 3e-53
Identities = 158/410 (38%), Positives = 199/410 (48%), Gaps = 86/410 (20%)
Query: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPS--V 125
GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD TVPS V
Sbjct: 94 GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
Query: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGL 185
SSI+R++R K F + A K G + +SI+G+
Sbjct: 154 SSISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGI 191
Query: 186 LGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQH 244
LG DK D D ++S+ RK R+ F+ LE LE FER H
Sbjct: 192 LG------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
Query: 245 YPEAYASP---------------------SHTKGEQGLYPLPLLNSTL-----DDGKATL 278
YP+ Y + + + G L N L G TL
Sbjct: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
Query: 279 TPSNTPLGRNLSTHQTYPVVAGREMVGPTLPGYPPHIP-TSGQGSYASSAIAGMVAGSEY 337
P P TYP + G T+ P P T QG A++A A
Sbjct: 301 PPYQLP-------DSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAA------D 347
Query: 338 SGNAYG-HTPYSSYSEAWRFPNS--------SLLSSPYYYSSTSRPSAPP 378
+ +AYG +SSYS+++ P + S SP S PSA P
Sbjct: 348 TSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVP 397
>gi|197276661 paired box 1 [Homo sapiens]
Length = 534
Score = 194 bits (494), Expect = 9e-50
Identities = 102/183 (55%), Positives = 122/183 (66%), Gaps = 8/183 (4%)
Query: 10 HGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYETG 69
+G +NQLGG FVNGRPLP +R RIV+LA G+RPCDISRQLRVSHGCVSKIL RY ETG
Sbjct: 99 YGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETG 158
Query: 70 SIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSIN 129
SI PG IGGSKP+V TP VV+ I DYK+ +P +FAWEIRDRLLA+GVCD VPSVSSI+
Sbjct: 159 SILPGAIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPSVSSIS 218
Query: 130 RIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAV-----TPPESPQSDSLGSTYSING 184
RI+R K+ +L P +P + + P SP +GS + G
Sbjct: 219 RILRNKIG---SLAQPGPYEASKQPPSQPTLPYNHIYQYPYPSPVSPTGAKMGSHPGVPG 275
Query: 185 LLG 187
G
Sbjct: 276 TAG 278
>gi|7242167 paired box 9 [Homo sapiens]
Length = 341
Score = 194 bits (493), Expect = 1e-49
Identities = 109/205 (53%), Positives = 130/205 (63%), Gaps = 33/205 (16%)
Query: 11 GGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYETGS 70
G +NQLGG FVNGRPLP +R RIV+LA G+RPCDISRQLRVSHGCVSKIL RY ETGS
Sbjct: 6 GEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGS 65
Query: 71 IRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINR 130
I PG IGGSKP+V TP VV+ I YK+++P +FAWEIRDRLLA+GVCD VPSVSSI+R
Sbjct: 66 ILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISR 125
Query: 131 IIRTKV----QQ-----------------PFN------LPMDSCVATKSLSPGHTLIPSS 163
I+R K+ QQ P+N P+ + A PG IP S
Sbjct: 126 ILRNKIGNLAQQGHYDSYKQHQPTPQPALPYNHIYSYPSPITAAAAKVPTPPGVPAIPGS 185
Query: 164 AVTPPESPQSDSLGSTYSINGLLGI 188
P P S++S+ +LGI
Sbjct: 186 VAMPRTWP------SSHSVTDILGI 204
>gi|7524356 paired box 3 isoform PAX3b [Homo sapiens]
Length = 206
Score = 191 bits (484), Expect = 1e-48
Identities = 91/128 (71%), Positives = 108/128 (84%), Gaps = 1/128 (0%)
Query: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSS 127
GSIRPG IGGSKPK V TP V +KI +YKR+NP MF+WEIRD+LL + VCD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 128 INRIIRTK 135
I+RI+R+K
Sbjct: 154 ISRILRSK 161
>gi|6654638 paired box 3 isoform PAX3a [Homo sapiens]
Length = 215
Score = 191 bits (484), Expect = 1e-48
Identities = 91/128 (71%), Positives = 108/128 (84%), Gaps = 1/128 (0%)
Query: 9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68
G G +NQLGG F+NGRPLP +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
Query: 69 GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSS 127
GSIRPG IGGSKPK V TP V +KI +YKR+NP MF+WEIRD+LL + VCD +TVPSVSS
Sbjct: 94 GSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSS 153
Query: 128 INRIIRTK 135
I+RI+R+K
Sbjct: 154 ISRILRSK 161
>gi|170784824 paired box 4 [Homo sapiens]
Length = 343
Score = 164 bits (415), Expect = 1e-40
Identities = 86/155 (55%), Positives = 107/155 (69%), Gaps = 1/155 (0%)
Query: 13 LNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIR 72
+NQLGG FVNGRPLP RQ+IV LA G+RPCDISR L+VS+GCVSKILGRYY TG +
Sbjct: 1 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE 60
Query: 73 PGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRII 132
P IGGSKP++ATP VV +I K + P +FAWEI+ +L AEG+C D PSVSSINR++
Sbjct: 61 PKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVL 120
Query: 133 RTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTP 167
R +Q+ LP + L+P S + TP
Sbjct: 121 RA-LQEDQGLPCTRLRSPAVLAPAVLTPHSGSETP 154
>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
Length = 411
Score = 41.2 bits (95), Expect = 0.002
Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 12/116 (10%)
Query: 143 PMDSCVATKSLSPGHTL---IP-----SSAVTPPESPQSDSLGSTYSINGLLGIAQPGSD 194
P D + + S GH+ +P SS P P SD++G S + G
Sbjct: 132 PPDGSLKLQEGSSGHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYLSVKEAGVKGPQ 191
Query: 195 KRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPFERQHYPEAYA 250
R SD S DS+S+ R++ T F+ + LE LE F++ HYP+ YA
Sbjct: 192 DRA--SSDLPSPLEKADSESNKGKKRRNRTT--FTSYQLEELEKVFQKTHYPDVYA 243
>gi|139394646 iroquois homeobox protein 5 [Homo sapiens]
Length = 483
Score = 39.3 bits (90), Expect = 0.006
Identities = 39/139 (28%), Positives = 54/139 (38%), Gaps = 15/139 (10%)
Query: 245 YPEAYA-SPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAGREM 303
YP+ Y PS LY P ++++ G P LGR+ S P
Sbjct: 3 YPQGYLYQPS---ASLALYSCPAYSTSVISG-----PRTDELGRSSSGSAFSPYAGSTAF 54
Query: 304 VGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNSSLLS 363
P+ PGY H+ A A A A S Y G+ Y HTP + S + + L S
Sbjct: 55 TAPS-PGYNSHLQYG-----ADPAAAAAAAFSSYVGSPYDHTPGMAGSLGYHPYAAPLGS 108
Query: 364 SPYYYSSTSRPSAPPTTAT 382
PY + + + TAT
Sbjct: 109 YPYGDPAYRKNATRDATAT 127
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,780,845
Number of Sequences: 37866
Number of extensions: 919703
Number of successful extensions: 2484
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 73
Number of HSP's that attempted gapping in prelim test: 2363
Number of HSP's gapped (non-prelim): 176
length of query: 387
length of database: 18,247,518
effective HSP length: 104
effective length of query: 283
effective length of database: 14,309,454
effective search space: 4049575482
effective search space used: 4049575482
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.