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Search of human proteins with 74315997
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|74315997 l-myc-1 proto-oncogene isoform 1 [Homo sapiens]
(364 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|74315997 l-myc-1 proto-oncogene isoform 1 [Homo sapiens] 761 0.0
gi|74315995 l-myc-1 proto-oncogene isoform 1 [Homo sapiens] 761 0.0
gi|239757875 PREDICTED: similar to L-myc-2 protein, partial [Hom... 423 e-118
gi|20127386 l-myc-1 proto-oncogene isoform 2 [Homo sapiens] 366 e-101
gi|19923312 v-myc myelocytomatosis viral related oncogene, neuro... 156 3e-38
gi|71774083 myc proto-oncogene protein [Homo sapiens] 153 3e-37
gi|21704263 MAX protein isoform b [Homo sapiens] 52 6e-07
gi|219283190 MAX dimerization protein 3 isoform b [Homo sapiens] 52 6e-07
gi|13775222 MAX dimerization protein 3 isoform a [Homo sapiens] 52 6e-07
gi|21704269 MAX protein isoform e [Homo sapiens] 50 2e-06
gi|21704265 MAX protein isoform c [Homo sapiens] 50 2e-06
gi|21704261 MAX protein isoform a [Homo sapiens] 50 2e-06
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 47 3e-05
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 47 3e-05
gi|47717116 MAX interactor 1 isoform b [Homo sapiens] 45 1e-04
gi|30795242 aryl hydrocarbon receptor nuclear translocator isofo... 44 2e-04
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 44 2e-04
gi|30795240 aryl hydrocarbon receptor nuclear translocator isofo... 43 4e-04
gi|4502231 aryl hydrocarbon receptor nuclear translocator isofor... 43 4e-04
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 43 4e-04
gi|237512940 early growth response 4 [Homo sapiens] 42 7e-04
gi|145199237 transcription elongation factor B polypeptide 3 bin... 42 7e-04
gi|57242782 MAX interactor 1 isoform a [Homo sapiens] 42 0.001
gi|9945318 MAX binding protein [Homo sapiens] 42 0.001
gi|52630419 sterol regulatory element binding transcription fact... 41 0.002
gi|22547195 sterol regulatory element binding transcription fact... 41 0.002
gi|68303555 aryl hydrocarbon receptor nuclear translocator 2 [Ho... 41 0.002
gi|98986461 neurogenic differentiation 2 [Homo sapiens] 40 0.003
gi|153792074 proline rich 12 [Homo sapiens] 40 0.003
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 40 0.003
>gi|74315997 l-myc-1 proto-oncogene isoform 1 [Homo sapiens]
Length = 364
Score = 761 bits (1964), Expect = 0.0
Identities = 364/364 (100%), Positives = 364/364 (100%)
Query: 1 MDYDSYQHYFYDYDCGEDFYRSTAPSEDIWKKFELVPSPPTSPPWGLGPGAGDPAPGIGP 60
MDYDSYQHYFYDYDCGEDFYRSTAPSEDIWKKFELVPSPPTSPPWGLGPGAGDPAPGIGP
Sbjct: 1 MDYDSYQHYFYDYDCGEDFYRSTAPSEDIWKKFELVPSPPTSPPWGLGPGAGDPAPGIGP 60
Query: 61 PEPWPGGCTGDEAESRGHSKGWGRNYASIIRRDCMWSGFSARERLERAVSDRLAPGAPRG 120
PEPWPGGCTGDEAESRGHSKGWGRNYASIIRRDCMWSGFSARERLERAVSDRLAPGAPRG
Sbjct: 61 PEPWPGGCTGDEAESRGHSKGWGRNYASIIRRDCMWSGFSARERLERAVSDRLAPGAPRG 120
Query: 121 NPPKASAAPDCTPSLEAGNPAPAAPCPLGEPKTQACSGSESPSDSENEEIDVVTVEKRQS 180
NPPKASAAPDCTPSLEAGNPAPAAPCPLGEPKTQACSGSESPSDSENEEIDVVTVEKRQS
Sbjct: 121 NPPKASAAPDCTPSLEAGNPAPAAPCPLGEPKTQACSGSESPSDSENEEIDVVTVEKRQS 180
Query: 181 LGIRKPVTITVRADPLDPCMKHFHISIHQQQHNYAARFPPESCSQEEASERGPQEEVLER 240
LGIRKPVTITVRADPLDPCMKHFHISIHQQQHNYAARFPPESCSQEEASERGPQEEVLER
Sbjct: 181 LGIRKPVTITVRADPLDPCMKHFHISIHQQQHNYAARFPPESCSQEEASERGPQEEVLER 240
Query: 241 DAAGEKEDEEDEEIVSPPPVESEAAQSCHPKPVSSDTEDVTKRKNHNFLERKRRNDLRSR 300
DAAGEKEDEEDEEIVSPPPVESEAAQSCHPKPVSSDTEDVTKRKNHNFLERKRRNDLRSR
Sbjct: 241 DAAGEKEDEEDEEIVSPPPVESEAAQSCHPKPVSSDTEDVTKRKNHNFLERKRRNDLRSR 300
Query: 301 FLALRDQVPTLASCSKAPKVVILSKALEYLQALVGAEKRMATEKRQLRCRQQQLQKRIAY 360
FLALRDQVPTLASCSKAPKVVILSKALEYLQALVGAEKRMATEKRQLRCRQQQLQKRIAY
Sbjct: 301 FLALRDQVPTLASCSKAPKVVILSKALEYLQALVGAEKRMATEKRQLRCRQQQLQKRIAY 360
Query: 361 LTGY 364
LTGY
Sbjct: 361 LTGY 364
>gi|74315995 l-myc-1 proto-oncogene isoform 1 [Homo sapiens]
Length = 364
Score = 761 bits (1964), Expect = 0.0
Identities = 364/364 (100%), Positives = 364/364 (100%)
Query: 1 MDYDSYQHYFYDYDCGEDFYRSTAPSEDIWKKFELVPSPPTSPPWGLGPGAGDPAPGIGP 60
MDYDSYQHYFYDYDCGEDFYRSTAPSEDIWKKFELVPSPPTSPPWGLGPGAGDPAPGIGP
Sbjct: 1 MDYDSYQHYFYDYDCGEDFYRSTAPSEDIWKKFELVPSPPTSPPWGLGPGAGDPAPGIGP 60
Query: 61 PEPWPGGCTGDEAESRGHSKGWGRNYASIIRRDCMWSGFSARERLERAVSDRLAPGAPRG 120
PEPWPGGCTGDEAESRGHSKGWGRNYASIIRRDCMWSGFSARERLERAVSDRLAPGAPRG
Sbjct: 61 PEPWPGGCTGDEAESRGHSKGWGRNYASIIRRDCMWSGFSARERLERAVSDRLAPGAPRG 120
Query: 121 NPPKASAAPDCTPSLEAGNPAPAAPCPLGEPKTQACSGSESPSDSENEEIDVVTVEKRQS 180
NPPKASAAPDCTPSLEAGNPAPAAPCPLGEPKTQACSGSESPSDSENEEIDVVTVEKRQS
Sbjct: 121 NPPKASAAPDCTPSLEAGNPAPAAPCPLGEPKTQACSGSESPSDSENEEIDVVTVEKRQS 180
Query: 181 LGIRKPVTITVRADPLDPCMKHFHISIHQQQHNYAARFPPESCSQEEASERGPQEEVLER 240
LGIRKPVTITVRADPLDPCMKHFHISIHQQQHNYAARFPPESCSQEEASERGPQEEVLER
Sbjct: 181 LGIRKPVTITVRADPLDPCMKHFHISIHQQQHNYAARFPPESCSQEEASERGPQEEVLER 240
Query: 241 DAAGEKEDEEDEEIVSPPPVESEAAQSCHPKPVSSDTEDVTKRKNHNFLERKRRNDLRSR 300
DAAGEKEDEEDEEIVSPPPVESEAAQSCHPKPVSSDTEDVTKRKNHNFLERKRRNDLRSR
Sbjct: 241 DAAGEKEDEEDEEIVSPPPVESEAAQSCHPKPVSSDTEDVTKRKNHNFLERKRRNDLRSR 300
Query: 301 FLALRDQVPTLASCSKAPKVVILSKALEYLQALVGAEKRMATEKRQLRCRQQQLQKRIAY 360
FLALRDQVPTLASCSKAPKVVILSKALEYLQALVGAEKRMATEKRQLRCRQQQLQKRIAY
Sbjct: 301 FLALRDQVPTLASCSKAPKVVILSKALEYLQALVGAEKRMATEKRQLRCRQQQLQKRIAY 360
Query: 361 LTGY 364
LTGY
Sbjct: 361 LTGY 364
>gi|239757875 PREDICTED: similar to L-myc-2 protein, partial [Homo
sapiens]
Length = 349
Score = 423 bits (1087), Expect = e-118
Identities = 213/296 (71%), Positives = 229/296 (77%), Gaps = 6/296 (2%)
Query: 1 MDYDSYQHYFYDYDCGEDFYRSTAPSEDIWKKFELVPSPPTSPPWGLGPGAGDPAPGIGP 60
MD DSY HYFYDYD GEDFYRST PSEDIWKKFELVP PPW LGP AG+PA G
Sbjct: 60 MDRDSYHHYFYDYDGGEDFYRSTTPSEDIWKKFELVP-----PPWDLGPAAGNPALSFGL 114
Query: 61 PEPWPGGCTGDEAESRGHSKGWGRNYASIIRRDCMWSGFSARERLERAVSDRLAPGAPRG 120
EPWP GC GDE ES+ + K W NYAS+IRRDCMWSGFS +E LERAVSD LA GAP G
Sbjct: 115 LEPWPVGCAGDETESQDYWKAWDANYASLIRRDCMWSGFSTQEPLERAVSDLLAVGAPSG 174
Query: 121 NPPKASAAPDCTPSLEAGNPAPAAPCPLGEPKTQACSGSESPSDSENEEIDVVTVEKRQS 180
PK A PD TP LEAGN AP PC LGEPK QACS SESPSDSE EEID VTV+KRQS
Sbjct: 175 YSPKEFATPDYTPELEAGNLAPIFPCLLGEPKIQACSRSESPSDSEGEEID-VTVKKRQS 233
Query: 181 LGIRKPVTITVRADPLDPCMKHFHISIHQQQHNYAARFPPESCSQEEASERGPQEEVLER 240
L RKPV I VRAD LDP M FHISIHQQQHNYAA FPPESC QE A +R P +E LER
Sbjct: 234 LSTRKPVIIAVRADLLDPRMNLFHISIHQQQHNYAAPFPPESCFQEGAPKRMPPKEALER 293
Query: 241 DAAGEKEDEEDEEIVSPPPVESEAAQSCHPKPVSSDTEDVTKRKNHNFLERKRRND 296
+A G K+D+EDEEIVS PPVESEAAQSC PKP+ DTE+ TK+K H++LERKRRND
Sbjct: 294 EAPGGKDDKEDEEIVSLPPVESEAAQSCQPKPIHYDTENWTKKKYHSYLERKRRND 349
>gi|20127386 l-myc-1 proto-oncogene isoform 2 [Homo sapiens]
Length = 206
Score = 366 bits (940), Expect = e-101
Identities = 165/165 (100%), Positives = 165/165 (100%)
Query: 1 MDYDSYQHYFYDYDCGEDFYRSTAPSEDIWKKFELVPSPPTSPPWGLGPGAGDPAPGIGP 60
MDYDSYQHYFYDYDCGEDFYRSTAPSEDIWKKFELVPSPPTSPPWGLGPGAGDPAPGIGP
Sbjct: 1 MDYDSYQHYFYDYDCGEDFYRSTAPSEDIWKKFELVPSPPTSPPWGLGPGAGDPAPGIGP 60
Query: 61 PEPWPGGCTGDEAESRGHSKGWGRNYASIIRRDCMWSGFSARERLERAVSDRLAPGAPRG 120
PEPWPGGCTGDEAESRGHSKGWGRNYASIIRRDCMWSGFSARERLERAVSDRLAPGAPRG
Sbjct: 61 PEPWPGGCTGDEAESRGHSKGWGRNYASIIRRDCMWSGFSARERLERAVSDRLAPGAPRG 120
Query: 121 NPPKASAAPDCTPSLEAGNPAPAAPCPLGEPKTQACSGSESPSDS 165
NPPKASAAPDCTPSLEAGNPAPAAPCPLGEPKTQACSGSESPSDS
Sbjct: 121 NPPKASAAPDCTPSLEAGNPAPAAPCPLGEPKTQACSGSESPSDS 165
>gi|19923312 v-myc myelocytomatosis viral related oncogene,
neuroblastoma derived [Homo sapiens]
Length = 464
Score = 156 bits (394), Expect = 3e-38
Identities = 161/472 (34%), Positives = 204/472 (43%), Gaps = 142/472 (30%)
Query: 1 MDYDSYQHYFYDYDCGEDFY----RSTAPSEDIWKKFELVPSPPTS------------PP 44
+++DS Q FY + +DFY ST P EDIWKKFEL+P+PP S P
Sbjct: 19 LEFDSLQPCFYPDE--DDFYFGGPDSTPPGEDIWKKFELLPTPPLSPSRGFAEHSSEPPS 76
Query: 45 W--------------------GLGPGAGDPAP---------------------------- 56
W GLG G G P
Sbjct: 77 WVTEMLLENELWGSPAEEDAFGLG-GLGGLTPNPVILQDCMWSGFSAREKLERAVSEKLQ 135
Query: 57 -GIGPPEPW-----PG-GCTGDEAESRGHSKGWGRNYASIIRR------DCMWSG----F 99
G GPP PG G G + G GR A++ +C+ F
Sbjct: 136 HGRGPPTAGSTAQSPGAGAASPAGRGHGGAAGAGRAGAALPAELAHPAAECVDPAVVFPF 195
Query: 100 SARERLERAVSDRLAPGAPRGNPPKASAAPDCTPSLEAGNPAPAAPCPLG------EPKT 153
+R E A AP P AS A P AG P A P P G + K
Sbjct: 196 PVNKR-EPAPVPAAPASAPAAGPAVASGAGIAAP---AGAPGVAPPRPGGRQTSGGDHKA 251
Query: 154 QACSGSESPSDS---------ENEEIDVVTVEKRQSLGIRKPVT---ITVR--------- 192
+ SG ++ SDS E EEIDVVTVEKR+S K VT ITVR
Sbjct: 252 LSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNTKAVTTFTITVRPKNAALGPG 311
Query: 193 -ADPLDPCMKHFHISIHQQQHNYAARFPPESCSQEEASERGPQEEVLERDAAGEKEDEED 251
A + +K + IHQQ HNYAA P SE P ++ ++ +A
Sbjct: 312 RAQSSELILKRC-LPIHQQ-HNYAAPSPYVE------SEDAPPQKKIKSEA--------- 354
Query: 252 EEIVSPPPVES---EAAQSCHPKPVSSDTEDVTKRKNHNFLERKRRNDLRSRFLALRDQV 308
SP P++S A+S P+ +SD+ED +R+NHN LER+RRNDLRS FL LRD V
Sbjct: 355 ----SPRPLKSVIPPKAKSLSPR--NSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHV 408
Query: 309 PTLASCSKAPKVVILSKALEYLQALVGAEKRMATEKRQLRCRQQQLQKRIAY 360
P L KA KVVIL KA EY+ +L E ++ EK +L+ RQQQL K+I +
Sbjct: 409 PELVKNEKAAKVVILKKATEYVHSLQAEEHQLLLEKEKLQARQQQLLKKIEH 460
>gi|71774083 myc proto-oncogene protein [Homo sapiens]
Length = 454
Score = 153 bits (386), Expect = 3e-37
Identities = 145/447 (32%), Positives = 201/447 (44%), Gaps = 112/447 (25%)
Query: 1 MDYDSYQHYFYDYDCGEDFYRST--------APSEDIWKKFELVPSPPTSPPWGLG---P 49
+DYDS Q YFY D E+FY+ APSEDIWKKFEL+P+PP SP G P
Sbjct: 29 LDYDSVQPYFY-CDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSP 87
Query: 50 GAGDPAPGIGPPEPWPGG---CTGDEAESRGHSKGWGRNYAS-------------IIRRD 93
P + GG T D+ E G S II +D
Sbjct: 88 SYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQD 147
Query: 94 CMWSGFSARERL--------ERAVSDRLAPGAPRGN------------------------ 121
CMWSGFSA +L + A D +P RG+
Sbjct: 148 CMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQDLSAAASECIDPS 207
Query: 122 -----PPKASAAPDCTPSLEAGNPAPAAPC--------PLGEPK-------TQACSGSES 161
P S++P S ++ +P++ P G P+ T + S+S
Sbjct: 208 VVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDS 267
Query: 162 PSDSENEE-IDVVTVEKRQSLGIR----KPVTITVRADPLDP-CMKHFHISIHQQQHNYA 215
+ E+EE IDVV+VEKRQ+ G R P P P +K H+S H QHNYA
Sbjct: 268 EEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRCHVSTH--QHNYA 325
Query: 216 ARFPPESCSQEEASERGPQEEV-LERDAAGEKEDEEDEEIVSPPPVESEAAQSCHPKPVS 274
A PP + A++R + V + R + ++ C P S
Sbjct: 326 A--PPSTRKDYPAAKRVKLDSVRVLRQISNNRK--------------------C-TSPRS 362
Query: 275 SDTEDVTKRKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAPKVVILSKALEYLQALV 334
SDTE+ KR+ HN LER+RRN+L+ F ALRDQ+P L + KAPKVVIL KA Y+ ++
Sbjct: 363 SDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQ 422
Query: 335 GAEKRMATEKRQLRCRQQQLQKRIAYL 361
E+++ +E+ LR R++QL+ ++ L
Sbjct: 423 AEEQKLISEEDLLRKRREQLKHKLEQL 449
>gi|21704263 MAX protein isoform b [Homo sapiens]
Length = 151
Score = 52.4 bits (124), Expect = 6e-07
Identities = 27/53 (50%), Positives = 35/53 (66%), Gaps = 1/53 (1%)
Query: 279 DVTKRKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAPKVVILSKALEYLQ 331
D KR +HN LERKRR+ ++ F +LRD VP+L KA + IL KA EY+Q
Sbjct: 12 DADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQG-EKASRAQILDKATEYIQ 63
>gi|219283190 MAX dimerization protein 3 isoform b [Homo sapiens]
Length = 193
Score = 52.4 bits (124), Expect = 6e-07
Identities = 28/81 (34%), Positives = 46/81 (56%)
Query: 283 RKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAPKVVILSKALEYLQALVGAEKRMAT 342
R HN LE++RR L+ L+ Q+P A C++ + +L +A ++Q L E+R
Sbjct: 59 RSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQ 118
Query: 343 EKRQLRCRQQQLQKRIAYLTG 363
K +LR +QQ LQ+++ L G
Sbjct: 119 LKERLRSKQQSLQRQLEQLRG 139
>gi|13775222 MAX dimerization protein 3 isoform a [Homo sapiens]
Length = 206
Score = 52.4 bits (124), Expect = 6e-07
Identities = 28/81 (34%), Positives = 46/81 (56%)
Query: 283 RKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAPKVVILSKALEYLQALVGAEKRMAT 342
R HN LE++RR L+ L+ Q+P A C++ + +L +A ++Q L E+R
Sbjct: 59 RSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQ 118
Query: 343 EKRQLRCRQQQLQKRIAYLTG 363
K +LR +QQ LQ+++ L G
Sbjct: 119 LKERLRSKQQSLQRQLEQLRG 139
>gi|21704269 MAX protein isoform e [Homo sapiens]
Length = 134
Score = 50.4 bits (119), Expect = 2e-06
Identities = 26/50 (52%), Positives = 34/50 (68%), Gaps = 1/50 (2%)
Query: 282 KRKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAPKVVILSKALEYLQ 331
KR +HN LERKRR+ ++ F +LRD VP+L KA + IL KA EY+Q
Sbjct: 24 KRAHHNALERKRRDHIKDSFHSLRDSVPSLQG-EKASRAQILDKATEYIQ 72
>gi|21704265 MAX protein isoform c [Homo sapiens]
Length = 103
Score = 50.4 bits (119), Expect = 2e-06
Identities = 26/50 (52%), Positives = 34/50 (68%), Gaps = 1/50 (2%)
Query: 282 KRKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAPKVVILSKALEYLQ 331
KR +HN LERKRR+ ++ F +LRD VP+L KA + IL KA EY+Q
Sbjct: 24 KRAHHNALERKRRDHIKDSFHSLRDSVPSLQG-EKASRAQILDKATEYIQ 72
>gi|21704261 MAX protein isoform a [Homo sapiens]
Length = 160
Score = 50.4 bits (119), Expect = 2e-06
Identities = 26/50 (52%), Positives = 34/50 (68%), Gaps = 1/50 (2%)
Query: 282 KRKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAPKVVILSKALEYLQ 331
KR +HN LERKRR+ ++ F +LRD VP+L KA + IL KA EY+Q
Sbjct: 24 KRAHHNALERKRRDHIKDSFHSLRDSVPSLQG-EKASRAQILDKATEYIQ 72
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 47.0 bits (110), Expect = 3e-05
Identities = 76/293 (25%), Positives = 100/293 (34%), Gaps = 60/293 (20%)
Query: 37 PSPPTSPPWGLGPGAGDPAPGIGPPEP--------WPGGCTGD-EAESRGHSKGWGRNYA 87
P PP PW AG PA PP P PG GD E E+ G +YA
Sbjct: 686 PGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYA 745
Query: 88 SIIRRDCMWSGFSARERLERAVSDRLAPGAPRGN--------------PPK-----ASAA 128
++ RR G SA R +V+ A G PR PPK + +
Sbjct: 746 TLTRR----PGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPS 801
Query: 129 PDCTPSLEAGNPAPAAPCPLGEPKTQACSGSESP---------SDSENEEIDVV-TVEKR 178
P+ P E+ P A P ++ SE P SD+E EE T R
Sbjct: 802 PEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSR 861
Query: 179 QSLGIRKP------VTITVRADPLDPCMKHFHI----SIHQQQHNYAARFPPESCSQEEA 228
S G P +TI R P P + + + + + R P +
Sbjct: 862 GSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRP-------KC 914
Query: 229 SERGPQEEVLERDAAGEKEDEEDEEIVSPPPVESEAAQSC-HPKPVSSDTEDV 280
ER P + L + SP P ES A S P+P S + V
Sbjct: 915 REREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGV 967
Score = 30.8 bits (68), Expect = 2.0
Identities = 17/46 (36%), Positives = 19/46 (41%), Gaps = 2/46 (4%)
Query: 115 PGAPRGNPPKASAAPDCTPSL--EAGNPAPAAPCPLGEPKTQACSG 158
P G P AS+ P PS G P P AP P +P C G
Sbjct: 941 PSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPG 986
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 47.0 bits (110), Expect = 3e-05
Identities = 76/293 (25%), Positives = 100/293 (34%), Gaps = 60/293 (20%)
Query: 37 PSPPTSPPWGLGPGAGDPAPGIGPPEP--------WPGGCTGD-EAESRGHSKGWGRNYA 87
P PP PW AG PA PP P PG GD E E+ G +YA
Sbjct: 768 PGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYA 827
Query: 88 SIIRRDCMWSGFSARERLERAVSDRLAPGAPRGN--------------PPK-----ASAA 128
++ RR G SA R +V+ A G PR PPK + +
Sbjct: 828 TLTRR----PGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPS 883
Query: 129 PDCTPSLEAGNPAPAAPCPLGEPKTQACSGSESP---------SDSENEEIDVV-TVEKR 178
P+ P E+ P A P ++ SE P SD+E EE T R
Sbjct: 884 PEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSR 943
Query: 179 QSLGIRKP------VTITVRADPLDPCMKHFHI----SIHQQQHNYAARFPPESCSQEEA 228
S G P +TI R P P + + + + + R P +
Sbjct: 944 GSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRP-------KC 996
Query: 229 SERGPQEEVLERDAAGEKEDEEDEEIVSPPPVESEAAQSC-HPKPVSSDTEDV 280
ER P + L + SP P ES A S P+P S + V
Sbjct: 997 REREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGV 1049
Score = 30.8 bits (68), Expect = 2.0
Identities = 17/46 (36%), Positives = 19/46 (41%), Gaps = 2/46 (4%)
Query: 115 PGAPRGNPPKASAAPDCTPSL--EAGNPAPAAPCPLGEPKTQACSG 158
P G P AS+ P PS G P P AP P +P C G
Sbjct: 1023 PSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPG 1068
>gi|47717116 MAX interactor 1 isoform b [Homo sapiens]
Length = 295
Score = 44.7 bits (104), Expect = 1e-04
Identities = 66/267 (24%), Positives = 99/267 (37%), Gaps = 53/267 (19%)
Query: 98 GFSARERLE-RAVSDRLAPGAPRGNPPKASAAPDCTPSLEAGNPAPAAPCPLGEPKTQAC 156
G R R E R LAP AP PP A AAP P +PA A P C
Sbjct: 2 GKRGRPRKEARCEGAGLAPAAPPAVPP-AVAAPQ--PPALPEDPAGAKP---------RC 49
Query: 157 SGSESPSDSENEEIDVVTVEKRQSLGIRKPVTITVRADPLDPCMKHFHISIHQQQHNYAA 216
S+ + SEN ++EK + ++ + A L+ K + +H YA+
Sbjct: 50 PFSDIFNTSEN------SMEKHINTFLQNVQILLEAASYLEQIEKENK----KCEHGYAS 99
Query: 217 RFPPESCSQEEASERGPQEEVLERDAAGEKEDEEDEEIVSPPPVESEAAQSCHPKPVSSD 276
FP + + S+ PP AQ S
Sbjct: 100 SFPSMPSPRLQHSK---------------------------PPRRLSRAQK---HSSGSS 129
Query: 277 TEDVTKRKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAPKVVILSKALEYLQALVGA 336
R HN LE+ RR LR L+ +P C++ + +L+KA +++ L A
Sbjct: 130 NTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEA 189
Query: 337 EKRMATEKRQLRCRQQQLQKRIAYLTG 363
E++ + L Q+ L+ R+ L G
Sbjct: 190 ERKSQHQLENLEREQRFLKWRLEQLQG 216
>gi|30795242 aryl hydrocarbon receptor nuclear translocator isoform
3 [Homo sapiens]
Length = 774
Score = 44.3 bits (103), Expect = 2e-04
Identities = 24/69 (34%), Positives = 42/69 (60%), Gaps = 2/69 (2%)
Query: 268 CHPKPVSSDTEDVTKRKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAP-KVVILSKA 326
C +S+D E R+NH+ +ER+RRN + + L D VPT ++ ++ P K+ IL A
Sbjct: 62 CDDDQMSNDKERFA-RENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMA 120
Query: 327 LEYLQALVG 335
+ ++++L G
Sbjct: 121 VSHMKSLRG 129
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 43.9 bits (102), Expect = 2e-04
Identities = 59/247 (23%), Positives = 89/247 (36%), Gaps = 29/247 (11%)
Query: 37 PSPPTSP-----PWGLGPGAGDPAPG-IGPPEP----WPGGCTGDEAESRGHSKGWGRNY 86
P PP P PW P P PG + P P +PG D S+G
Sbjct: 449 PPPPPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADPDDVLTVTESSRG----- 503
Query: 87 ASIIRRDCMWSGFSARERLER-----AVSDRLAPGAPRGNPP----KASAAPDCTPSLEA 137
+ +C+W AR R A AP AP NP +A + P P + A
Sbjct: 504 ---LNLECLWE--KARRGAGRGGGAPAWQPASAPPAPHANPSNPFYEALSTPSVLPVISA 558
Query: 138 GNPAPAAPCPLGEPKTQACSGSESPSDSENEEIDVVTVEKRQSLGIRKPVTITVRADPLD 197
+P+ ++ + + + P+D + + V + Q+ + A PL
Sbjct: 559 RSPSVSSEYYIRLEEHGSPPEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVSETWASPLF 618
Query: 198 PCMKHFHISIHQQQHNYAARFPPESCSQEEASERGPQEEVLERDAAGEKEDEEDEEIVSP 257
P + F + + PE E P E + ER A E+EE+EE S
Sbjct: 619 PAPRPFPAQSSASGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSS 678
Query: 258 PPVESEA 264
P +S +
Sbjct: 679 PGEDSSS 685
>gi|30795240 aryl hydrocarbon receptor nuclear translocator isoform
2 [Homo sapiens]
Length = 328
Score = 43.1 bits (100), Expect = 4e-04
Identities = 22/63 (34%), Positives = 40/63 (63%), Gaps = 1/63 (1%)
Query: 274 SSDTEDVTKRKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAP-KVVILSKALEYLQA 332
SS ++ R+NH+ +ER+RRN + + L D VPT ++ ++ P K+ IL A+ ++++
Sbjct: 82 SSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKS 141
Query: 333 LVG 335
L G
Sbjct: 142 LRG 144
>gi|4502231 aryl hydrocarbon receptor nuclear translocator isoform 1
[Homo sapiens]
Length = 789
Score = 43.1 bits (100), Expect = 4e-04
Identities = 22/63 (34%), Positives = 40/63 (63%), Gaps = 1/63 (1%)
Query: 274 SSDTEDVTKRKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAP-KVVILSKALEYLQA 332
SS ++ R+NH+ +ER+RRN + + L D VPT ++ ++ P K+ IL A+ ++++
Sbjct: 82 SSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKS 141
Query: 333 LVG 335
L G
Sbjct: 142 LRG 144
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 43.1 bits (100), Expect = 4e-04
Identities = 60/280 (21%), Positives = 107/280 (38%), Gaps = 33/280 (11%)
Query: 35 LVPSPPTSPPWGLG------PGAGDPAPGIGPPEPWPGGCTGDEAESRGHSKGWGRNYAS 88
LVPS P P + + A GI P+P G G+E S K NY+
Sbjct: 799 LVPSLPYPPQKVVAHTEFTTSSDSETANGIAKPDPVMPG--GEEKASPFGIKLRRTNYS- 855
Query: 89 IIRRDCMWSGFSARERLERAVSDRLAPGAP-----RGNPPKASAAPDCTPSL-------- 135
+R +C +++ + D G P RG A PSL
Sbjct: 856 -LRFNCDQQAEQKKKKRHSSTGDSADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQAP 914
Query: 136 ----EAGNPAPAAPCPLGEPKTQACSGSESPSDSENEEIDVVTVEKRQSLGIRKPVTITV 191
++ P+ + P+ P S S++P+ ++ + + + ++ +L KP + T
Sbjct: 915 STRRDSAEPSSSRSVPVAHPGPPPAS-SQTPAPEHDKAANKMPLAQKPALA-PKPTSQTP 972
Query: 192 RADPLDPCMKHFHISIHQQQHNYAARFPPE-SCSQEEASERGPQEEVLERDAAGEKEDEE 250
A PL + + + + ++ P E S +E+S+R P + G+K DEE
Sbjct: 973 PASPLSKLSRPYLVELLSRRAGRPDPEPSEPSKEDQESSDRRPPSPPGPEERKGQKRDEE 1032
Query: 251 DEEI---VSPPPVESEAAQSCHPKPVSSDTEDVTKRKNHN 287
+E + PP+ + + P + E + H+
Sbjct: 1033 EEATERKPASPPLPATQQEKPSQTPEAGRKEKPMLQSRHS 1072
>gi|237512940 early growth response 4 [Homo sapiens]
Length = 589
Score = 42.4 bits (98), Expect = 7e-04
Identities = 36/106 (33%), Positives = 44/106 (41%), Gaps = 25/106 (23%)
Query: 55 APGIGPPEPWP------GGCTGDEAESRGHSKGWGRNYASIIRRDCMWSGFSARERLERA 108
A G+G PEP P GGC G G +++ RR G +AR R RA
Sbjct: 4 ARGVGSPEPAPPQLYKWGGC------------GLGEPGSALERR-----GAAARGRCGRA 46
Query: 109 VSDRLAPGAPRGNPPKASAAPDCTPSLEAGNPAPAAPCPLGEPKTQ 154
+ RL PRG PK A S+ G P P A P P+ Q
Sbjct: 47 RAPRLPDSFPRGECPKPGAR--APRSVRCGEPLPPASPPPARPQAQ 90
>gi|145199237 transcription elongation factor B polypeptide 3
binding protein 1 [Homo sapiens]
Length = 1221
Score = 42.4 bits (98), Expect = 7e-04
Identities = 51/216 (23%), Positives = 81/216 (37%), Gaps = 41/216 (18%)
Query: 40 PTSPPWGLGPGAGD--PAPGIGPPEPW----------PGGCTGDEAESRGHSKGWGRNYA 87
P P P +GD PA G GPP P P G E ++R +G ++
Sbjct: 451 PDRPARRPSPTSGDSRPAAGRGPPRPLQLPDRKSTKAPSGKLV-ERKARSLDEGASQDAP 509
Query: 88 SIIRRDCMWSGFSARERLERAVSDRLAPGAPRGNP---PKASAAPDCTPSLEAGNPAPAA 144
+ +R + E + A PG P P P S+ D G P
Sbjct: 510 KLKKRALSHADLFGDESEDEAAG----PGVPSVWPSALPSLSSDSDSDSDSSLGFPEAQG 565
Query: 145 P------CPLGEPKTQACSGSESPSDSENEEIDVVTVEKRQSLGIRKPVTITVRADPLDP 198
P P P + S S S + S ++D +EK + +DP++
Sbjct: 566 PPKRLKASPPPSPAPSSSSSSSSSTSSAGADVDYSALEKE----------VDFDSDPMEE 615
Query: 199 CMKHFH--ISIHQQQHNYAARFPPESCSQEEASERG 232
C++ F+ S+ + AR PP+ +E++ E+G
Sbjct: 616 CLRIFNESTSVKTEDRGRLARQPPK---EEKSEEKG 648
>gi|57242782 MAX interactor 1 isoform a [Homo sapiens]
Length = 228
Score = 41.6 bits (96), Expect = 0.001
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 3/108 (2%)
Query: 256 SPPPVESEAAQSCHPKPVSSDTEDVTKRKNHNFLERKRRNDLRSRFLALRDQVPTLASCS 315
S PP AQ S R HN LE+ RR LR L+ +P C+
Sbjct: 45 SKPPRRLSRAQK---HSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCT 101
Query: 316 KAPKVVILSKALEYLQALVGAEKRMATEKRQLRCRQQQLQKRIAYLTG 363
+ + +L+KA +++ L AE++ + L Q+ L+ R+ L G
Sbjct: 102 RHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQG 149
>gi|9945318 MAX binding protein [Homo sapiens]
Length = 582
Score = 41.6 bits (96), Expect = 0.001
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 6/110 (5%)
Query: 257 PPPVESEAAQSCHPKPVSSDTED-----VTKRKNHNFLERKRRNDLRSRFLALRDQVPTL 311
PPP + + V S + + R+ HN LE+ RR L+ F L+ +P +
Sbjct: 191 PPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIPNV 250
Query: 312 ASCSKAPKVVILSKALEYLQALVGAEKRMATEKRQLRCRQQQLQKRIAYL 361
K + +L AL Y+Q+L EK E +L + Q+R+A L
Sbjct: 251 DD-KKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAEL 299
>gi|52630419 sterol regulatory element binding transcription factor
1 isoform a [Homo sapiens]
Length = 1177
Score = 40.8 bits (94), Expect = 0.002
Identities = 26/90 (28%), Positives = 47/90 (52%), Gaps = 5/90 (5%)
Query: 259 PVESEAAQSCHPKPVSSDTEDVTKRKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAP 318
P+ AA S P S E KR HN +E++ R+ + + + L+D V + + +K
Sbjct: 334 PINRLAAGSKAPASAQSRGE---KRTAHNAIEKRYRSSINDKIIELKDLV--VGTEAKLN 388
Query: 319 KVVILSKALEYLQALVGAEKRMATEKRQLR 348
K +L KA++Y++ L + +++ E LR
Sbjct: 389 KSAVLRKAIDYIRFLQHSNQKLKQENLSLR 418
>gi|22547195 sterol regulatory element binding transcription factor
1 isoform b [Homo sapiens]
Length = 1147
Score = 40.8 bits (94), Expect = 0.002
Identities = 26/90 (28%), Positives = 47/90 (52%), Gaps = 5/90 (5%)
Query: 259 PVESEAAQSCHPKPVSSDTEDVTKRKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAP 318
P+ AA S P S E KR HN +E++ R+ + + + L+D V + + +K
Sbjct: 304 PINRLAAGSKAPASAQSRGE---KRTAHNAIEKRYRSSINDKIIELKDLV--VGTEAKLN 358
Query: 319 KVVILSKALEYLQALVGAEKRMATEKRQLR 348
K +L KA++Y++ L + +++ E LR
Sbjct: 359 KSAVLRKAIDYIRFLQHSNQKLKQENLSLR 388
>gi|68303555 aryl hydrocarbon receptor nuclear translocator 2 [Homo
sapiens]
Length = 717
Score = 40.8 bits (94), Expect = 0.002
Identities = 19/54 (35%), Positives = 35/54 (64%), Gaps = 1/54 (1%)
Query: 283 RKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAP-KVVILSKALEYLQALVG 335
R+NH+ +ER+RRN + L D VPT ++ ++ P K+ IL A+ +++++ G
Sbjct: 65 RENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRG 118
>gi|98986461 neurogenic differentiation 2 [Homo sapiens]
Length = 382
Score = 40.4 bits (93), Expect = 0.003
Identities = 35/117 (29%), Positives = 49/117 (41%), Gaps = 15/117 (12%)
Query: 226 EEASERGPQEEVLERDAAGEKEDEEDEEIVSPPPVESEAAQSCHPKPVSSDTEDVTK--- 282
EE +E E E + GE+E+EE+EE + A+ PK +TK
Sbjct: 63 EEGTEATLAEVKEEGELGGEEEEEEEEE------EGLDEAEGERPKKRGPKKRKMTKARL 116
Query: 283 ------RKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAPKVVILSKALEYLQAL 333
R+ N ER R +DL + LR VP + K K+ L A Y+ AL
Sbjct: 117 ERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWAL 173
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 40.4 bits (93), Expect = 0.003
Identities = 33/103 (32%), Positives = 43/103 (41%), Gaps = 20/103 (19%)
Query: 50 GAGDPAPGIGPP-EPWPGGCT--------GDEAESRGHSKGWGRNYASIIRRDCMWSGFS 100
G G+P+PG G P + P G T G EA G + G G Y II+ +G
Sbjct: 335 GGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTG-- 392
Query: 101 ARERLERAVSDRLAPGAPRGNPPKASAAPDCTPSLEAGNPAPA 143
+ A GA R PP+++A P C G PA A
Sbjct: 393 ------KGGYGAAAGGATRPPPPRSTATPKCQ---SLGGPAAA 426
Score = 29.3 bits (64), Expect = 5.8
Identities = 40/157 (25%), Positives = 57/157 (36%), Gaps = 30/157 (19%)
Query: 38 SPPTSPPWGLGPGAGDPAPGIGP--------PEPWPGGCTG-----DEAESRGHSKGWG- 83
+PP SPP + P PA G+ P P P P G G + AES G G
Sbjct: 1304 TPPLSPPKSVPPSV--PARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPS 1361
Query: 84 ----------RNYASIIRRDCMWSGFSARER-LERAVSDRLAPGAPRGNPPKASAAPDCT 132
RN ++ A+ R L+ ++S ++ +PP A T
Sbjct: 1362 PCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISA---LDDPPLAGPKDTST 1418
Query: 133 PSLEAGNPAPAAPCPLGEPKTQACSGSESPSDSENEE 169
P PA A P P P + + + +P EE
Sbjct: 1419 PDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEE 1455
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 40.0 bits (92), Expect = 0.003
Identities = 40/150 (26%), Positives = 62/150 (41%), Gaps = 17/150 (11%)
Query: 122 PPKASAAPDCTPSLEAGNPAPAAPCPLGEPKTQACSGSESPSDSENEEIDVVTVEKRQSL 181
PP +SA P SL P P A ++++ S S+S SDSE+E + E
Sbjct: 444 PPSSSAPPSAPQSL----PEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEE----- 494
Query: 182 GIRKPVTITVRADPLDPCMKHFHISIHQQQHNYAARFPPESCSQEEASERGPQEEVLERD 241
+P+ T +P P + + + + A PPE E R P+ + D
Sbjct: 495 --NEPLE-TPAPEPEPPTTNKWQLDNWLTKVSQPAA-PPEGPRSTEPPRRHPESKG-SSD 549
Query: 242 AAGEKEDEEDEEIVSPPPVESEAAQSCHPK 271
+A +E E ++ PPP S A P+
Sbjct: 550 SATSQEHSESKD---PPPKSSSKAPRAPPE 576
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,768,605
Number of Sequences: 37866
Number of extensions: 1193413
Number of successful extensions: 11004
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 198
Number of HSP's successfully gapped in prelim test: 536
Number of HSP's that attempted gapping in prelim test: 8429
Number of HSP's gapped (non-prelim): 2523
length of query: 364
length of database: 18,247,518
effective HSP length: 104
effective length of query: 260
effective length of database: 14,309,454
effective search space: 3720458040
effective search space used: 3720458040
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.