Guide to the Human Genome
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Search of human proteins with 74275354

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|74275354 glutamate receptor, ionotropic, AMPA 2 isoform 1
precursor [Homo sapiens]
         (883 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|74275354 glutamate receptor, ionotropic, AMPA 2 isoform 1 pre...  1767   0.0  
gi|134304848 glutamate receptor, ionotropic, AMPA 2 isoform 2 pr...  1749   0.0  
gi|134304851 glutamate receptor, ionotropic, AMPA 2 isoform 3 [H...  1675   0.0  
gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2 p...  1351   0.0  
gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1 p...  1308   0.0  
gi|163659856 glutamate receptor, ionotrophic, AMPA 3 isoform 1 p...  1307   0.0  
gi|163659858 glutamate receptor, ionotrophic, AMPA 3 isoform 2 p...  1290   0.0  
gi|167001484 glutamate receptor, ionotropic, AMPA 1 isoform 2 [H...  1254   0.0  
gi|167001419 glutamate receptor, ionotropic, AMPA 1 isoform 1 [H...  1244   0.0  
gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1 ...   615   e-176
gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2 ...   615   e-176
gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor ...   594   e-169
gi|28416444 glutamate receptor, ionotropic, kainate 1 isoform 2 ...   593   e-169
gi|4504117 glutamate receptor, ionotropic, kainate 1 isoform 1 p...   584   e-166
gi|116284390 glutamate receptor, ionotrophic, AMPA 4 isoform 3 p...   514   e-145
gi|164419739 glutamate receptor, ionotrophic, AMPA 4 isoform 3 p...   514   e-145
gi|29029595 glutamate receptor KA1 precursor [Homo sapiens]           509   e-144
gi|29029597 glutamate receptor KA2 precursor [Homo sapiens]           507   e-143
gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [H...   350   4e-96
gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens]   347   4e-95
gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens]    235   2e-61
gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens]    235   2e-61
gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens]    235   2e-61
gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor ...   187   4e-47
gi|55770854 N-methyl-D-aspartate receptor subunit 2C precursor [...   182   1e-45
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ...   175   1e-43
gi|197313638 N-methyl-D-aspartate receptor subunit 2A isoform 2 ...   172   2e-42
gi|197313636 N-methyl-D-aspartate receptor subunit 2A isoform 1 ...   172   2e-42
gi|4504125 N-methyl-D-aspartate receptor subunit 2A isoform 1 pr...   172   2e-42
gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate...   165   2e-40

>gi|74275354 glutamate receptor, ionotropic, AMPA 2 isoform 1
           precursor [Homo sapiens]
          Length = 883

 Score = 1767 bits (4577), Expect = 0.0
 Identities = 883/883 (100%), Positives = 883/883 (100%)

Query: 1   MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTP 60
           MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTP
Sbjct: 1   MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTP 60

Query: 61  HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG 120
           HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG
Sbjct: 61  HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG 120

Query: 121 THPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINV 180
           THPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINV
Sbjct: 121 THPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINV 180

Query: 181 GNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL 240
           GNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL
Sbjct: 181 GNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL 240

Query: 241 GFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALT 300
           GFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALT
Sbjct: 241 GFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALT 300

Query: 301 YDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNI 360
           YDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNI
Sbjct: 301 YDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNI 360

Query: 361 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTT 420
           KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTT
Sbjct: 361 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTT 420

Query: 421 ILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKI 480
           ILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKI
Sbjct: 421 ILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKI 480

Query: 481 WNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 540
           WNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD
Sbjct: 481 WNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 540

Query: 541 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWF 600
           PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWF
Sbjct: 541 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWF 600

Query: 601 SLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL 660
           SLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL
Sbjct: 601 SLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL 660

Query: 661 SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGK 720
           SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGK
Sbjct: 661 SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGK 720

Query: 721 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVL 780
           YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVL
Sbjct: 721 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVL 780

Query: 781 DKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 840
           DKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR
Sbjct: 781 DKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 840

Query: 841 AEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883
           AEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI
Sbjct: 841 AEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883


>gi|134304848 glutamate receptor, ionotropic, AMPA 2 isoform 2
           precursor [Homo sapiens]
          Length = 883

 Score = 1749 bits (4530), Expect = 0.0
 Identities = 874/883 (98%), Positives = 877/883 (99%)

Query: 1   MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTP 60
           MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTP
Sbjct: 1   MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTP 60

Query: 61  HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG 120
           HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG
Sbjct: 61  HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG 120

Query: 121 THPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINV 180
           THPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINV
Sbjct: 121 THPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINV 180

Query: 181 GNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL 240
           GNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL
Sbjct: 181 GNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL 240

Query: 241 GFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALT 300
           GFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALT
Sbjct: 241 GFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALT 300

Query: 301 YDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNI 360
           YDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNI
Sbjct: 301 YDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNI 360

Query: 361 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTT 420
           KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTT
Sbjct: 361 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTT 420

Query: 421 ILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKI 480
           ILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKI
Sbjct: 421 ILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKI 480

Query: 481 WNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 540
           WNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD
Sbjct: 481 WNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 540

Query: 541 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWF 600
           PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWF
Sbjct: 541 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWF 600

Query: 601 SLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL 660
           SLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL
Sbjct: 601 SLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL 660

Query: 661 SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGK 720
           SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGK
Sbjct: 661 SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGK 720

Query: 721 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVL 780
           YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLR  VNLAVLKL+EQG+L
Sbjct: 721 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLL 780

Query: 781 DKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 840
           DKLKNKWWYDKGECG+    SKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR
Sbjct: 781 DKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 840

Query: 841 AEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883
           AEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI
Sbjct: 841 AEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883


>gi|134304851 glutamate receptor, ionotropic, AMPA 2 isoform 3 [Homo
           sapiens]
          Length = 836

 Score = 1675 bits (4338), Expect = 0.0
 Identities = 836/836 (100%), Positives = 836/836 (100%)

Query: 48  MVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL 107
           MVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL
Sbjct: 1   MVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL 60

Query: 108 HVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDS 167
           HVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDS
Sbjct: 61  HVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDS 120

Query: 168 AAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIG 227
           AAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIG
Sbjct: 121 AAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIG 180

Query: 228 KHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPG 287
           KHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPG
Sbjct: 181 KHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPG 240

Query: 288 AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA 347
           AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA
Sbjct: 241 AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA 300

Query: 348 LKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGND 407
           LKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGND
Sbjct: 301 LKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGND 360

Query: 408 TSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVG 467
           TSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVG
Sbjct: 361 TSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVG 420

Query: 468 DGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK 527
           DGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK
Sbjct: 421 DGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK 480

Query: 528 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSE 587
           PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSE
Sbjct: 481 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSE 540

Query: 588 STNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 647
           STNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV
Sbjct: 541 STNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 600

Query: 648 ERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 707
           ERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT
Sbjct: 601 ERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 660

Query: 708 AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPV 767
           AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPV
Sbjct: 661 AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPV 720

Query: 768 NLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLA 827
           NLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLA
Sbjct: 721 NLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLA 780

Query: 828 MLVALIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883
           MLVALIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI
Sbjct: 781 MLVALIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 836


>gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2
           precursor [Homo sapiens]
          Length = 884

 Score = 1351 bits (3496), Expect = 0.0
 Identities = 653/889 (73%), Positives = 767/889 (86%), Gaps = 11/889 (1%)

Query: 1   MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- 55
           M+ I    VLL    WGL  G   +S+QIGGLF R  DQEY+AFR+ +   +TS      
Sbjct: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60

Query: 56  -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP 114
            F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC  LH+S ITP
Sbjct: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120

Query: 115 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174
           SFPT+G   FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A +  W 
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180

Query: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234
           V+AI V N N    D  YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVKGYH
Sbjct: 181 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 236

Query: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK 294
           YIIANLGF D  L +   GGANV+GFQ+VD++  +V K ++RW  L+++EYPG+ T   K
Sbjct: 237 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 295

Query: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354
           YTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV+++
Sbjct: 296 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 355

Query: 355 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK 414
           GL+GN++FD  G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+       GNDT+ +EN+
Sbjct: 356 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENR 415

Query: 415 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGAR 474
           TVVVTTI+ESPYVM KKNHEM EGN++YEGYCVDLA+EIAKH G KYK+ IV DGKYGAR
Sbjct: 416 TVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGAR 475

Query: 475 DADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 534
           DADTKIWNGMVGELVYGKA+IAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG
Sbjct: 476 DADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 535

Query: 535 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGI 594
           VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEE EDG+E  S +  NEFGI
Sbjct: 536 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGI 595

Query: 595 FNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI 654
           FNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI
Sbjct: 596 FNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI 655

Query: 655 ESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARV 714
           ESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMWTYMRSAEPSVF RTTAEGVARV
Sbjct: 656 ESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARV 715

Query: 715 RKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKL 774
           RKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSSL   VNLAVLKL
Sbjct: 716 RKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKL 775

Query: 775 SEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIE 834
           +EQG+LDKLKNKWWYDKGECG+    SK+KTSALSLSNVAGVFYILVGGLGLAMLVALIE
Sbjct: 776 NEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIE 835

Query: 835 FCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883
           FCYKSRAEAKRMKVAK+AQ  NP+SSQN+QN ATY+EGYNVYG ES+KI
Sbjct: 836 FCYKSRAEAKRMKVAKSAQTFNPTSSQNTQNLATYREGYNVYGTESIKI 884


>gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1
           precursor [Homo sapiens]
          Length = 902

 Score = 1308 bits (3386), Expect = 0.0
 Identities = 633/854 (74%), Positives = 740/854 (86%), Gaps = 11/854 (1%)

Query: 1   MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- 55
           M+ I    VLL    WGL  G   +S+QIGGLF R  DQEY+AFR+ +   +TS      
Sbjct: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60

Query: 56  -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP 114
            F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC  LH+S ITP
Sbjct: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120

Query: 115 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174
           SFPT+G   FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A +  W 
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180

Query: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234
           V+AI V N N    D  YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVKGYH
Sbjct: 181 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 236

Query: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK 294
           YIIANLGF D  L +   GGANV+GFQ+VD++  +V K ++RW  L+++EYPG+ T   K
Sbjct: 237 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 295

Query: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354
           YTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV+++
Sbjct: 296 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 355

Query: 355 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK 414
           GL+GN++FD  G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+       GNDT+ +EN+
Sbjct: 356 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENR 415

Query: 415 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGAR 474
           TVVVTTI+ESPYVM KKNHEM EGN++YEGYCVDLA+EIAKH G KYK+ IV DGKYGAR
Sbjct: 416 TVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGAR 475

Query: 475 DADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 534
           DADTKIWNGMVGELVYGKA+IAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG
Sbjct: 476 DADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 535

Query: 535 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGI 594
           VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEE EDG+E  S +  NEFGI
Sbjct: 536 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGI 595

Query: 595 FNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI 654
           FNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI
Sbjct: 596 FNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI 655

Query: 655 ESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARV 714
           ESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMWTYMRSAEPSVF RTTAEGVARV
Sbjct: 656 ESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARV 715

Query: 715 RKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKL 774
           RKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSSL TPVNLAVLKL
Sbjct: 716 RKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKL 775

Query: 775 SEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIE 834
           SE GVLDKLKNKWWYDKGECG KDSGSK+KTSALSLSNVAGVFYILVGGLGLAMLVALIE
Sbjct: 776 SEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIE 835

Query: 835 FCYKSRAEAKRMKV 848
           FCYKSRAEAKRMK+
Sbjct: 836 FCYKSRAEAKRMKL 849


>gi|163659856 glutamate receptor, ionotrophic, AMPA 3 isoform 1
           precursor [Homo sapiens]
          Length = 894

 Score = 1307 bits (3383), Expect = 0.0
 Identities = 637/890 (71%), Positives = 762/890 (85%), Gaps = 12/890 (1%)

Query: 2   QKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE------ 55
           Q ++     L   L G   G   N+I IGGLF R   QE+SAFR  +  ++T++      
Sbjct: 9   QSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKP 68

Query: 56  FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPS 115
           F L  H+D+L+ +NSF+VTNAFCSQFSRGVYAIFGFYD+ S+NT+TSFCG LH SF+TPS
Sbjct: 69  FHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPS 128

Query: 116 FPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQV 175
           FPTD    FVIQMRP LKGA+LSL+ +Y+W+KF YLYD++RG S LQA++++A +  WQV
Sbjct: 129 FPTDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQV 188

Query: 176 TAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHY 235
           TA +VGNI   K  + +R + ++++ ++E+R ++DCE +++N I++QV+ +GKH +GYHY
Sbjct: 189 TARSVGNI---KDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHY 245

Query: 236 IIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKY 295
           ++ANLGFTD  L ++  GGAN++GFQIV+ ++ +V +FI+RW  L+E+E+P A    +KY
Sbjct: 246 MLANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKY 305

Query: 296 TSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEG 355
           TSALT+DA+ V+ EAFR LR+QR+++SRRG+AGDCLANPAVPW QG++IERALK VQV+G
Sbjct: 306 TSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQG 365

Query: 356 LSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKT 415
           ++GNI+FD  G+R NYTI++ E+K +G RK GYW+E ++ V   ++    ND++  EN+T
Sbjct: 366 MTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFV-PFSDQQISNDSASSENRT 424

Query: 416 VVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 475
           +VVTTILESPYVM KKNHE LEGNERYEGYCVDLA EIAKH   KYKL+IVGDGKYGARD
Sbjct: 425 IVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARD 484

Query: 476 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 535
            +TKIWNGMVGELVYG+ADIA+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV
Sbjct: 485 PETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 544

Query: 536 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEF-EDGRETQSS-ESTNEFG 593
           FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH E+  E+ R+ QS  +  NEFG
Sbjct: 545 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFG 604

Query: 594 IFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 653
           IFNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP
Sbjct: 605 IFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 664

Query: 654 IESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVAR 713
           IESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMW+YM+SAEPSVF +TTA+GVAR
Sbjct: 665 IESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVAR 724

Query: 714 VRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLK 773
           VRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+L TPVNLAVLK
Sbjct: 725 VRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLK 784

Query: 774 LSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALI 833
           LSEQG+LDKLKNKWWYDKGECGAKDSGSK+KTSALSLSNVAGVFYILVGGLGLAM+VALI
Sbjct: 785 LSEQGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALI 844

Query: 834 EFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883
           EFCYKSRAE+KRMK+ KN QN  P+ + N+QN+ATY+EGYNVYG ESVKI
Sbjct: 845 EFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI 894


>gi|163659858 glutamate receptor, ionotrophic, AMPA 3 isoform 2
           precursor [Homo sapiens]
          Length = 894

 Score = 1290 bits (3337), Expect = 0.0
 Identities = 629/890 (70%), Positives = 756/890 (84%), Gaps = 12/890 (1%)

Query: 2   QKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE------ 55
           Q ++     L   L G   G   N+I IGGLF R   QE+SAFR  +  ++T++      
Sbjct: 9   QSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKP 68

Query: 56  FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPS 115
           F L  H+D+L+ +NSF+VTNAFCSQFSRGVYAIFGFYD+ S+NT+TSFCG LH SF+TPS
Sbjct: 69  FHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPS 128

Query: 116 FPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQV 175
           FPTD    FVIQMRP LKGA+LSL+ +Y+W+KF YLYD++RG S LQA++++A +  WQV
Sbjct: 129 FPTDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQV 188

Query: 176 TAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHY 235
           TA +VGNI   K  + +R + ++++ ++E+R ++DCE +++N I++QV+ +GKH +GYHY
Sbjct: 189 TARSVGNI---KDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHY 245

Query: 236 IIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKY 295
           ++ANLGFTD  L ++  GGAN++GFQIV+ ++ +V +FI+RW  L+E+E+P A    +KY
Sbjct: 246 MLANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKY 305

Query: 296 TSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEG 355
           TSALT+DA+ V+ EAFR LR+QR+++SRRG+AGDCLANPAVPW QG++IERALK VQV+G
Sbjct: 306 TSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQG 365

Query: 356 LSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKT 415
           ++GNI+FD  G+R NYTI++ E+K +G RK GYW+E ++ V   ++    ND++  EN+T
Sbjct: 366 MTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFV-PFSDQQISNDSASSENRT 424

Query: 416 VVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 475
           +VVTTILESPYVM KKNHE LEGNERYEGYCVDLA EIAKH   KYKL+IVGDGKYGARD
Sbjct: 425 IVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARD 484

Query: 476 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 535
            +TKIWNGMVGELVYG+ADIA+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV
Sbjct: 485 PETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 544

Query: 536 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEF-EDGRETQSS-ESTNEFG 593
           FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH E+  E+ R+ QS  +  NEFG
Sbjct: 545 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFG 604

Query: 594 IFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 653
           IFNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP
Sbjct: 605 IFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 664

Query: 654 IESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVAR 713
           IESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMW+YM+SAEPSVF +TTA+GVAR
Sbjct: 665 IESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVAR 724

Query: 714 VRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLK 773
           VRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+L   VNLAVLK
Sbjct: 725 VRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGNAVNLAVLK 784

Query: 774 LSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALI 833
           L+EQG+LDKLKNKWWYDKGECG+    SK+KTSALSLSNVAGVFYILVGGLGLAM+VALI
Sbjct: 785 LNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMMVALI 844

Query: 834 EFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883
           EFCYKSRAE+KRMK+ KN QN  P+ + N+QN+ATY+EGYNVYG ESVKI
Sbjct: 845 EFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI 894


>gi|167001484 glutamate receptor, ionotropic, AMPA 1 isoform 2 [Homo
           sapiens]
          Length = 906

 Score = 1254 bits (3244), Expect = 0.0
 Identities = 607/845 (71%), Positives = 724/845 (85%), Gaps = 6/845 (0%)

Query: 4   IMHISVLLSPVLWGLIFGVS-SNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHI 62
           + HI         G + G +  N+IQIGGLFP    QE++AFR  + Q  T   +L P I
Sbjct: 1   MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQL-TEPPKLLPQI 59

Query: 63  DNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTH 122
           D + +++SF +T  FCSQFS+GVYAIFGFY++++VN +TSFCG LHV FITPSFP D ++
Sbjct: 60  DIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSN 119

Query: 123 PFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGN 182
            FV+Q+RP+L+ AL+S+I++Y+W KF Y+YD+DRGLS LQ VLD+AAEK WQVTA+N+  
Sbjct: 120 QFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILT 179

Query: 183 INNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGF 242
                 +E YR LFQDLE KKER V++DCE +++N I+ Q+I + K+  GYHYI+ANLGF
Sbjct: 180 TT----EEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGF 235

Query: 243 TDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYD 302
            D DL K +  GANV+GFQ+V+Y D++ +K +++W   + +++        KYTSALTYD
Sbjct: 236 MDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYD 295

Query: 303 AVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKF 362
            V+VM EAF++LR+QRI+ISRRGNAGDCLANPAVPWGQG++I+RAL+QV+ EGL+GN++F
Sbjct: 296 GVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQF 355

Query: 363 DQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTIL 422
           ++ G+R NYT++++E+K +G RKIGYW+E DK V   T+  +G D S ++N+T +VTTIL
Sbjct: 356 NEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL 415

Query: 423 ESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWN 482
           E PYVM+KKN    EGN+RYEGYCV+LAAEIAKH G+ Y+L IV DGKYGARD DTK WN
Sbjct: 416 EDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWN 475

Query: 483 GMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL 542
           GMVGELVYG+AD+A+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL
Sbjct: 476 GMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL 535

Query: 543 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSL 602
           AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH+EEFE+GR+  +S+ +NEFGIFNSLWFSL
Sbjct: 536 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSL 595

Query: 603 GAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSK 662
           GAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL+K
Sbjct: 596 GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK 655

Query: 663 QTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYA 722
           QTEIAYGTL++GSTKEFFRRSKIAVF+KMWTYM+SAEPSVFVRTT EG+ RVRKSKGKYA
Sbjct: 656 QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYA 715

Query: 723 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDK 782
           YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGS+LR PVNLAVLKLSEQGVLDK
Sbjct: 716 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDK 775

Query: 783 LKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAE 842
           LK+KWWYDKGECG+KDSGSK+KTSALSLSNVAGVFYIL+GGLGLAMLVALIEFCYKSR+E
Sbjct: 776 LKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSE 835

Query: 843 AKRMK 847
           +KRMK
Sbjct: 836 SKRMK 840


>gi|167001419 glutamate receptor, ionotropic, AMPA 1 isoform 1 [Homo
           sapiens]
          Length = 906

 Score = 1244 bits (3220), Expect = 0.0
 Identities = 602/845 (71%), Positives = 720/845 (85%), Gaps = 6/845 (0%)

Query: 4   IMHISVLLSPVLWGLIFGVS-SNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHI 62
           + HI         G + G +  N+IQIGGLFP    QE++AFR  + Q  T   +L P I
Sbjct: 1   MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQL-TEPPKLLPQI 59

Query: 63  DNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTH 122
           D + +++SF +T  FCSQFS+GVYAIFGFY++++VN +TSFCG LHV FITPSFP D ++
Sbjct: 60  DIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSN 119

Query: 123 PFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGN 182
            FV+Q+RP+L+ AL+S+I++Y+W KF Y+YD+DRGLS LQ VLD+AAEK WQVTA+N+  
Sbjct: 120 QFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILT 179

Query: 183 INNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGF 242
                 +E YR LFQDLE KKER V++DCE +++N I+ Q+I + K+  GYHYI+ANLGF
Sbjct: 180 TT----EEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGF 235

Query: 243 TDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYD 302
            D DL K +  GANV+GFQ+V+Y D++ +K +++W   + +++        KYTSALTYD
Sbjct: 236 MDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYD 295

Query: 303 AVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKF 362
            V+VM EAF++LR+QRI+ISRRGNAGDCLANPAVPWGQG++I+RAL+QV+ EGL+GN++F
Sbjct: 296 GVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQF 355

Query: 363 DQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTIL 422
           ++ G+R NYT++++E+K +G RKIGYW+E DK V   T+  +G D S ++N+T +VTTIL
Sbjct: 356 NEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL 415

Query: 423 ESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWN 482
           E PYVM+KKN    EGN+RYEGYCV+LAAEIAKH G+ Y+L IV DGKYGARD DTK WN
Sbjct: 416 EDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWN 475

Query: 483 GMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL 542
           GMVGELVYG+AD+A+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL
Sbjct: 476 GMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL 535

Query: 543 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSL 602
           AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH+EEFE+GR+  +S+ +NEFGIFNSLWFSL
Sbjct: 536 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSL 595

Query: 603 GAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSK 662
           GAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL+K
Sbjct: 596 GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK 655

Query: 663 QTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYA 722
           QTEIAYGTL++GSTKEFFRRSKIAVF+KMWTYM+SAEPSVFVRTT EG+ RVRKSKGKYA
Sbjct: 656 QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYA 715

Query: 723 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDK 782
           YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGS+LR PVNLAVLKL+EQG+LDK
Sbjct: 716 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDK 775

Query: 783 LKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAE 842
           LKNKWWYDKGECG+    SK+KTSALSLSNVAGVFYIL+GGLGLAMLVALIEFCYKSR+E
Sbjct: 776 LKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSE 835

Query: 843 AKRMK 847
           +KRMK
Sbjct: 836 SKRMK 840


>gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1
           precursor [Homo sapiens]
          Length = 908

 Score =  615 bits (1585), Expect = e-176
 Identities = 346/862 (40%), Positives = 511/862 (59%), Gaps = 50/862 (5%)

Query: 10  LLSPVLWGLIFGVSSNSIQIGGLF------PRGADQEYSAFRVGMVQFSTS---EFRLTP 60
           LL  +LW      +++ ++ GG+F      P GA++    F V  +  + +      LT 
Sbjct: 19  LLLCLLWIGYSQGTTHVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTY 78

Query: 61  HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFP--- 117
               + + +SF  +   C Q S GV AIFG     S N + S C  L V  I   +    
Sbjct: 79  DTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQV 138

Query: 118 TDGTHPFVIQMRPD---LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174
           +D    F + + PD   L  A+L L+++++W     +YD   GL  LQ ++ + +    +
Sbjct: 139 SDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLR 198

Query: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234
              + +  +  D KD   + L ++++  KE  VI DC  +    I+ Q + +G   + YH
Sbjct: 199 ---LKIRQLPADTKDA--KPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYH 253

Query: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYP-----GAH 289
           YI   L     D+   ++ G N++GF+I++ +++ VS  IE+WS +E  + P     G  
Sbjct: 254 YIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWS-MERLQAPPKPDSGLL 312

Query: 290 TTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALK 349
              +   +AL YDAV V++ A +   +  +   +         N   PW  G      +K
Sbjct: 313 DGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQ--------CNRHKPWRFGTRFMSLIK 364

Query: 350 QVQVEGLSGNIKFDQ-NGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSG--- 405
           +   EGL+G I F++ NG R ++ ++++ LK  G  KIG W     +   +TE   G   
Sbjct: 365 EAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGL--NMTESQKGKPA 422

Query: 406 NDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTI 465
           N T  L N++++VTTILE PYV+ KK+ + L GN+R+EGYC+DL  E++   GF Y++ +
Sbjct: 423 NITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRL 482

Query: 466 VGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMI 525
           V DGKYGA+D     WNGMV EL+  KAD+A+APL IT VRE+VIDFSKPFM+LGISI+ 
Sbjct: 483 VEDGKYGAQDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILY 542

Query: 526 KKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQS 585
           +KP  + PGVFSFL+PL+ +IWM I+ AY+GVS VLF+++RFSPYEW+           S
Sbjct: 543 RKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPH---PCNPDS 599

Query: 586 SESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFL 645
               N F + NS WF +GA M+QG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFL
Sbjct: 600 DVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFL 659

Query: 646 TVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVR 705
           TVERM SPI+SA+DL+KQT+I YG ++ G+T  FF++SKI+ +DKMW +M S   SV V+
Sbjct: 660 TVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVK 719

Query: 706 TTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRT 765
           +  EG+ RV  S   YA+L+EST  E++ QR  C+  ++GG +DSKGYG+ TP GS  R 
Sbjct: 720 SNEEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRD 776

Query: 766 PVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLG 825
            + +A+L+L E+G L  +K KWW   G C  ++S   ++ SAL + N+ G+F +L  GL 
Sbjct: 777 KITIAILQLQEEGKLHMMKEKWWRGNG-CPEEES---KEASALGVQNIGGIFIVLAAGLV 832

Query: 826 LAMLVALIEFCYKSRAEAKRMK 847
           L++ VA+ EF YKS+  A+  K
Sbjct: 833 LSVFVAVGEFLYKSKKNAQLEK 854


>gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2
           precursor [Homo sapiens]
          Length = 869

 Score =  615 bits (1585), Expect = e-176
 Identities = 346/862 (40%), Positives = 511/862 (59%), Gaps = 50/862 (5%)

Query: 10  LLSPVLWGLIFGVSSNSIQIGGLF------PRGADQEYSAFRVGMVQFSTS---EFRLTP 60
           LL  +LW      +++ ++ GG+F      P GA++    F V  +  + +      LT 
Sbjct: 19  LLLCLLWIGYSQGTTHVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTY 78

Query: 61  HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFP--- 117
               + + +SF  +   C Q S GV AIFG     S N + S C  L V  I   +    
Sbjct: 79  DTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQV 138

Query: 118 TDGTHPFVIQMRPD---LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174
           +D    F + + PD   L  A+L L+++++W     +YD   GL  LQ ++ + +    +
Sbjct: 139 SDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLR 198

Query: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234
              + +  +  D KD   + L ++++  KE  VI DC  +    I+ Q + +G   + YH
Sbjct: 199 ---LKIRQLPADTKDA--KPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYH 253

Query: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYP-----GAH 289
           YI   L     D+   ++ G N++GF+I++ +++ VS  IE+WS +E  + P     G  
Sbjct: 254 YIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWS-MERLQAPPKPDSGLL 312

Query: 290 TTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALK 349
              +   +AL YDAV V++ A +   +  +   +         N   PW  G      +K
Sbjct: 313 DGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQ--------CNRHKPWRFGTRFMSLIK 364

Query: 350 QVQVEGLSGNIKFDQ-NGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSG--- 405
           +   EGL+G I F++ NG R ++ ++++ LK  G  KIG W     +   +TE   G   
Sbjct: 365 EAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGL--NMTESQKGKPA 422

Query: 406 NDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTI 465
           N T  L N++++VTTILE PYV+ KK+ + L GN+R+EGYC+DL  E++   GF Y++ +
Sbjct: 423 NITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRL 482

Query: 466 VGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMI 525
           V DGKYGA+D     WNGMV EL+  KAD+A+APL IT VRE+VIDFSKPFM+LGISI+ 
Sbjct: 483 VEDGKYGAQDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILY 542

Query: 526 KKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQS 585
           +KP  + PGVFSFL+PL+ +IWM I+ AY+GVS VLF+++RFSPYEW+           S
Sbjct: 543 RKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPH---PCNPDS 599

Query: 586 SESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFL 645
               N F + NS WF +GA M+QG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFL
Sbjct: 600 DVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFL 659

Query: 646 TVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVR 705
           TVERM SPI+SA+DL+KQT+I YG ++ G+T  FF++SKI+ +DKMW +M S   SV V+
Sbjct: 660 TVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVK 719

Query: 706 TTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRT 765
           +  EG+ RV  S   YA+L+EST  E++ QR  C+  ++GG +DSKGYG+ TP GS  R 
Sbjct: 720 SNEEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRD 776

Query: 766 PVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLG 825
            + +A+L+L E+G L  +K KWW   G C  ++S   ++ SAL + N+ G+F +L  GL 
Sbjct: 777 KITIAILQLQEEGKLHMMKEKWWRGNG-CPEEES---KEASALGVQNIGGIFIVLAAGLV 832

Query: 826 LAMLVALIEFCYKSRAEAKRMK 847
           L++ VA+ EF YKS+  A+  K
Sbjct: 833 LSVFVAVGEFLYKSKKNAQLEK 854


>gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor
           [Homo sapiens]
          Length = 919

 Score =  594 bits (1532), Expect = e-169
 Identities = 329/803 (40%), Positives = 484/803 (60%), Gaps = 43/803 (5%)

Query: 58  LTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTL---HVSFITP 114
           LT  I  +   +SF  T   C Q + GV AIFG       N + S C  L   H+     
Sbjct: 79  LTYDIQRIHFHDSFEATKKACDQLALGVVAIFGPSQGSCTNAVQSICNALEVPHIQLRWK 138

Query: 115 SFPTDGTHPFVIQMRPD---LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEK 171
             P D    F + + PD   L  A+L L++Y +W     +YD   GL  LQ ++   A  
Sbjct: 139 HHPLDNKDTFYVNLYPDYASLSHAILDLVQYLKWRSATVVYDDSTGLIRLQELI--MAPS 196

Query: 172 KWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVK 231
           ++ +  + +  +  D  D   R L ++++  +E R+I DC       I+ Q + +G   +
Sbjct: 197 RYNIR-LKIRQLPIDSDDS--RPLLKEMKRGREFRIIFDCSHTMAAQILKQAMAMGMMTE 253

Query: 232 GYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYP----G 287
            YH+I   L     DL   ++ G N++GF+I++ D+  VS  +E+WS    +  P    G
Sbjct: 254 YYHFIFTTLDLYALDLEPYRYSGVNLTGFRILNVDNPHVSAIVEKWSMERLQAAPRSESG 313

Query: 288 AHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERA 347
                +   +AL YDAV +++  ++   +  +      N+  C  + A  W  G      
Sbjct: 314 LLDGVMMTDAALLYDAVHIVSVCYQRAPQMTV------NSLQCHRHKA--WRFGGRFMNF 365

Query: 348 LKQVQVEGLSGNIKFDQ-NGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSG- 405
           +K+ Q EGL+G I F++ +G R ++ ++I+ LK +G  K+G WS  D +   +TE+  G 
Sbjct: 366 IKEAQWEGLTGRIVFNKTSGLRTDFDLDIISLKEDGLEKVGVWSPADGL--NITEVAKGR 423

Query: 406 --NDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKL 463
             N T  L N++++VTT+LE P+VM +K+   L GN+R+EGYC+DL  E+A   GF Y++
Sbjct: 424 GPNVTDSLTNRSLIVTTVLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEI 483

Query: 464 TIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISI 523
            +V DGKYGA+D D   WNGMV EL+  KAD+A+APLTIT VRE+ IDFSKPFM+LG+SI
Sbjct: 484 RLVEDGKYGAQD-DKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSI 542

Query: 524 MIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH-TEEFEDGRE 582
           + +KP  + P VFSFL+PL+ +IWM ++ AY+GVS VLF+++RFSPYEW+       G E
Sbjct: 543 LYRKPNGTNPSVFSFLNPLSPDIWMYVLLAYLGVSCVLFVIARFSPYEWYDAHPCNPGSE 602

Query: 583 TQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLA 642
                  N F + NS WF +G+ M+QG ++ P++LS RI+GG+WWFFTLIIISSYTANLA
Sbjct: 603 VVE----NNFTLLNSFWFGMGSLMQQGSELMPKALSTRIIGGIWWFFTLIIISSYTANLA 658

Query: 643 AFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSV 702
           AFLTVERM SPI+SA+DL+KQT+I YG +  G+T  FF++SKI+ F+KMW +M S++PS 
Sbjct: 659 AFLTVERMESPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFM-SSKPSA 717

Query: 703 FVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSS 762
            V+   EG+ R   +   YA L+EST  EY+ QR  C+  ++GG +DSKGYGI TP GS 
Sbjct: 718 LVKNNEEGIQRALTA--DYALLMESTTIEYVTQRN-CNLTQIGGLIDSKGYGIGTPMGSP 774

Query: 763 LRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVG 822
            R  + +A+L+L E+  L  +K KWW   G C  +++   ++ SAL +  + G+F +L  
Sbjct: 775 YRDKITIAILQLQEEDKLHIMKEKWWRGSG-CPEEEN---KEASALGIQKIGGIFIVLAA 830

Query: 823 GLGLAMLVALIEFCYKSRAEAKR 845
           GL L++LVA+ EF YK R  A+R
Sbjct: 831 GLVLSVLVAVGEFVYKLRKTAER 853


>gi|28416444 glutamate receptor, ionotropic, kainate 1 isoform 2
           precursor [Homo sapiens]
          Length = 905

 Score =  593 bits (1529), Expect = e-169
 Identities = 337/839 (40%), Positives = 499/839 (59%), Gaps = 53/839 (6%)

Query: 27  IQIGGLFPRGADQ----EYSAFRVGMVQFSTSEF-----RLTPHIDNLEVANSFAVTNAF 77
           ++IGG+F    ++    E  AF+  +   + +        LT  I  + + +SF  +   
Sbjct: 37  LRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRA 96

Query: 78  CSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHP-------FVIQMRP 130
           C Q + GV A+FG     SV+ + S C  L V    P   T   HP       F I + P
Sbjct: 97  CDQLALGVAALFGPSHSSSVSAVQSICNALEV----PHIQTRWKHPSVDNKDLFYINLYP 152

Query: 131 D---LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDK 187
           D   +  A+L L+ YY W     +Y+   GL  LQ ++ + +    ++    + + N D 
Sbjct: 153 DYAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDA 212

Query: 188 KDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDL 247
           K      L ++++  KE  VI DC  +   +I+ Q++ +G   + YHY    L     DL
Sbjct: 213 KP-----LLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDL 267

Query: 248 LKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK----YTSALTYDA 303
              ++ G N++GF++++ D+  VS  IE+WS    +  P   T  +       +AL YDA
Sbjct: 268 ELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDA 327

Query: 304 VQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFD 363
           V ++  A  + R  ++ +S          +   PW  G      +K+ + +GL+G+I F+
Sbjct: 328 VYMV--AIASHRASQLTVS------SLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFN 379

Query: 364 Q-NGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELP-SGNDTSGLENKTVVVTTI 421
           + NG R ++ ++I+ LK  G  KIG W+    + +T +    S N T  L N+T++VTTI
Sbjct: 380 KTNGLRKDFDLDIISLKEEGTEKIGIWNSNSGLNMTDSNKDKSSNITDSLANRTLIVTTI 439

Query: 422 LESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIW 481
           LE PYVM +K+ + L GN+R+EGYC+DL  E++   GF Y + +V DGKYGA++ D   W
Sbjct: 440 LEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQN-DKGEW 498

Query: 482 NGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDP 541
           NGMV EL+  +AD+A+APLTIT VRE+VIDFSKPFM+LGISI+ +KP  + PGVFSFL+P
Sbjct: 499 NGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNP 558

Query: 542 LAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFS 601
           L+ +IWM ++ A +GVS VLF+++RF+PYEW+           S    N F + NS WF 
Sbjct: 559 LSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPH---PCNPDSDVVENNFTLLNSFWFG 615

Query: 602 LGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLS 661
           +GA M+QG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFLTVERM SPI+SA+DL+
Sbjct: 616 VGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLA 675

Query: 662 KQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKY 721
           KQT+I YG +  GST  FF++SKI+ ++KMW +M S + +  VR + EG+ RV  +   Y
Sbjct: 676 KQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTT--DY 733

Query: 722 AYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLD 781
           A L+EST  EY+ QR  C+  ++GG +DSKGYG+ TP GS  R  + +A+L+L E+G L 
Sbjct: 734 ALLMESTSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLH 792

Query: 782 KLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 840
            +K KWW   G C  +D+   ++ SAL + N+ G+F +L  GL L++ VA+ EF YKSR
Sbjct: 793 MMKEKWWRGNG-CPEEDN---KEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSR 847


>gi|4504117 glutamate receptor, ionotropic, kainate 1 isoform 1
           precursor [Homo sapiens]
          Length = 918

 Score =  584 bits (1505), Expect = e-166
 Identities = 337/854 (39%), Positives = 500/854 (58%), Gaps = 68/854 (7%)

Query: 27  IQIGGLFPRGADQ----EYSAFRVGMVQFSTSEF-----RLTPHIDNLEVANSFAVTNAF 77
           ++IGG+F    ++    E  AF+  +   + +        LT  I  + + +SF  +   
Sbjct: 37  LRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRA 96

Query: 78  CSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHP-------FVIQMRP 130
           C Q + GV A+FG     SV+ + S C  L V    P   T   HP       F I + P
Sbjct: 97  CDQLALGVAALFGPSHSSSVSAVQSICNALEV----PHIQTRWKHPSVDNKDLFYINLYP 152

Query: 131 D---LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDK 187
           D   +  A+L L+ YY W     +Y+   GL  LQ ++ + +    ++    + + N D 
Sbjct: 153 DYAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDA 212

Query: 188 KDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDL 247
           K      L ++++  KE  VI DC  +   +I+ Q++ +G   + YHY    L     DL
Sbjct: 213 KP-----LLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDL 267

Query: 248 LKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK----YTSALTYDA 303
              ++ G N++GF++++ D+  VS  IE+WS    +  P   T  +       +AL YDA
Sbjct: 268 ELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDA 327

Query: 304 VQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFD 363
           V ++  A  + R  ++ +S          +   PW  G      +K+ + +GL+G+I F+
Sbjct: 328 VYMV--AIASHRASQLTVS------SLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFN 379

Query: 364 Q-NGKRINYTINIMELKTNGP---------------RKIGYWSEVDKMVVTLTELP-SGN 406
           + NG R ++ ++I+ LK  G                +KIG W+    + +T +    S N
Sbjct: 380 KTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTDSNKDKSSN 439

Query: 407 DTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIV 466
            T  L N+T++VTTILE PYVM +K+ + L GN+R+EGYC+DL  E++   GF Y + +V
Sbjct: 440 ITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLV 499

Query: 467 GDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIK 526
            DGKYGA++ D   WNGMV EL+  +AD+A+APLTIT VRE+VIDFSKPFM+LGISI+ +
Sbjct: 500 PDGKYGAQN-DKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYR 558

Query: 527 KPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSS 586
           KP  + PGVFSFL+PL+ +IWM ++ A +GVS VLF+++RF+PYEW+           S 
Sbjct: 559 KPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPH---PCNPDSD 615

Query: 587 ESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLT 646
              N F + NS WF +GA M+QG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFLT
Sbjct: 616 VVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLT 675

Query: 647 VERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRT 706
           VERM SPI+SA+DL+KQT+I YG +  GST  FF++SKI+ ++KMW +M S + +  VR 
Sbjct: 676 VERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRN 735

Query: 707 TAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTP 766
           + EG+ RV  +   YA L+EST  EY+ QR  C+  ++GG +DSKGYG+ TP GS  R  
Sbjct: 736 SDEGIQRVLTT--DYALLMESTSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGSPYRDK 792

Query: 767 VNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGL 826
           + +A+L+L E+G L  +K KWW   G C  +D+   ++ SAL + N+ G+F +L  GL L
Sbjct: 793 ITIAILQLQEEGKLHMMKEKWWRGNG-CPEEDN---KEASALGVENIGGIFIVLAAGLVL 848

Query: 827 AMLVALIEFCYKSR 840
           ++ VA+ EF YKSR
Sbjct: 849 SVFVAIGEFIYKSR 862


>gi|116284390 glutamate receptor, ionotrophic, AMPA 4 isoform 3
           precursor [Homo sapiens]
          Length = 433

 Score =  514 bits (1325), Expect = e-145
 Identities = 239/428 (55%), Positives = 330/428 (77%), Gaps = 11/428 (2%)

Query: 1   MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- 55
           M+ I    VLL    WGL  G   +S+QIGGLF R  DQEY+AFR+ +   +TS      
Sbjct: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60

Query: 56  -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP 114
            F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC  LH+S ITP
Sbjct: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120

Query: 115 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174
           SFPT+G   FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A +  W 
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180

Query: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234
           V+AI V N N    D  YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVKGYH
Sbjct: 181 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 236

Query: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK 294
           YIIANLGF D  L +   GGANV+GFQ+VD++  +V K ++RW  L+++EYPG+ T   K
Sbjct: 237 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 295

Query: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354
           YTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV+++
Sbjct: 296 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 355

Query: 355 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK 414
           GL+GN++FD  G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+       GNDT+ +EN+
Sbjct: 356 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENR 415

Query: 415 TVVVTTIL 422
           TVVVTTI+
Sbjct: 416 TVVVTTIM 423


>gi|164419739 glutamate receptor, ionotrophic, AMPA 4 isoform 3
           precursor [Homo sapiens]
          Length = 433

 Score =  514 bits (1325), Expect = e-145
 Identities = 239/428 (55%), Positives = 330/428 (77%), Gaps = 11/428 (2%)

Query: 1   MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- 55
           M+ I    VLL    WGL  G   +S+QIGGLF R  DQEY+AFR+ +   +TS      
Sbjct: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60

Query: 56  -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP 114
            F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC  LH+S ITP
Sbjct: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120

Query: 115 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174
           SFPT+G   FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A +  W 
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180

Query: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234
           V+AI V N N    D  YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVKGYH
Sbjct: 181 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 236

Query: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK 294
           YIIANLGF D  L +   GGANV+GFQ+VD++  +V K ++RW  L+++EYPG+ T   K
Sbjct: 237 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 295

Query: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354
           YTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV+++
Sbjct: 296 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 355

Query: 355 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK 414
           GL+GN++FD  G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+       GNDT+ +EN+
Sbjct: 356 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENR 415

Query: 415 TVVVTTIL 422
           TVVVTTI+
Sbjct: 416 TVVVTTIM 423


>gi|29029595 glutamate receptor KA1 precursor [Homo sapiens]
          Length = 956

 Score =  509 bits (1312), Expect = e-144
 Identities = 301/796 (37%), Positives = 449/796 (56%), Gaps = 41/796 (5%)

Query: 69  NSFAVTNAFCSQFSRGVYAIFG-FYDKKSVNTITSFCGTLHV-----------SFITPSF 116
           + +      C    +GV A+ G      S + I++ CG   V            F    F
Sbjct: 75  SEYETAETMCQILPKGVVAVLGPSSSPASSSIISNICGEKEVPHFKVAPEEFVKFQFQRF 134

Query: 117 PTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVT 176
            T   HP       D+  A+  ++ ++       +      L  L+ +L      K  ++
Sbjct: 135 TTLNLHP----SNTDISVAVAGILNFFNCTTACLICAKAECLLNLEKLLRQFLISKDTLS 190

Query: 177 AINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYI 236
                 + +D +D     L +++   K   +I+       + I+ +   +G     Y YI
Sbjct: 191 V----RMLDDTRDPT--PLLKEIRDDKTATIIIHANASMSHTILLKAAELGMVSAYYTYI 244

Query: 237 IANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYT 296
             NL F+   +  +     N+ GF I +   +   +F +  +   ++       T    +
Sbjct: 245 FTNLEFSLQRMDSLVDDRVNILGFSIFNQSHAFFQEFAQSLNQSWQENCDHVPFTGPALS 304

Query: 297 SALTYDAVQVMTEAFRNL-RKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEG 355
           SAL +DAV  +  A + L R Q I +             A  W  G  +   L+ V++EG
Sbjct: 305 SALLFDAVYAVVTAVQELNRSQEIGVKPLS------CGSAQIWQHGTSLMNYLRMVELEG 358

Query: 356 LSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKT 415
           L+G+I+F+  G+R NY + I++   NG R+IG W   + + +  + L + N +  L N T
Sbjct: 359 LTGHIEFNSKGQRSNYALKILQFTRNGFRQIGQWHVAEGLSMD-SHLYASNISDTLFNTT 417

Query: 416 VVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 475
           +VVTTILE+PY+M+K NH+ +EGN+RYEG+CVD+  E+A+   F YK+ +VGDG YG  +
Sbjct: 418 LVVTTILENPYLMLKGNHQEMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPE 477

Query: 476 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 535
           A+   W GMVGEL+  KAD+A+A LTIT  RE+VIDFSKPFM+LGISI+ +     KPG 
Sbjct: 478 ANGT-WTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGY 536

Query: 536 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIF 595
           FSFLDP +  +W+ ++ AY+ VS VLFLV+R +PYEW++       + + +   N++ + 
Sbjct: 537 FSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPH--PCAQGRCNLLVNQYSLG 594

Query: 596 NSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIE 655
           NSLWF +G FM+QG  I+PR+LS R V GVWW FTLIIISSYTANLAAFLTV+RM  PIE
Sbjct: 595 NSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMDVPIE 654

Query: 656 SAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVR 715
           S +DL+ QT I YGT+  GS+  FF+ S+   + +MW YM S +PSVFV++T EG+ARV 
Sbjct: 655 SVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVL 714

Query: 716 KSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLS 775
            S   YA+LLESTMNEY  QR  C+  ++GG LD+KGYGI  P GS  R   +LA+L+L 
Sbjct: 715 NS--NYAFLLESTMNEYYRQRN-CNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQ 771

Query: 776 EQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEF 835
           E   L+ LK KWW + G+C  ++     +   L + N+ G+F +L+ GL +A+ +A++EF
Sbjct: 772 ENNRLEILKRKWW-EGGKCPKEED---HRAKGLGMENIGGIFVVLICGLIVAIFMAMLEF 827

Query: 836 CYKSR-AEAKRMKVAK 850
            +  R +EA  + V +
Sbjct: 828 LWTLRHSEATEVSVCQ 843


>gi|29029597 glutamate receptor KA2 precursor [Homo sapiens]
          Length = 980

 Score =  507 bits (1306), Expect = e-143
 Identities = 300/805 (37%), Positives = 454/805 (56%), Gaps = 38/805 (4%)

Query: 57  RLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFG-FYDKKSVNTITSFCGTLHVSFI--- 112
           R+   I  L+  + +  T+  C    +GV ++ G      S +T++  CG   +  I   
Sbjct: 62  RVEVDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSPASASTVSHICGEKEIPHIKVG 121

Query: 113 ---TPS-----FPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAV 164
              TP      F +   +P       D+  A+  +++ + +   + +      L  L+ +
Sbjct: 122 PEETPRLQYLRFASVSLYP----SNEDVSLAVSRILKSFNYPSASLICAKAECLLRLEEL 177

Query: 165 LDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVI 224
           +      K  ++      + +D +D     L +++   K   +I+D      + I+ +  
Sbjct: 178 VRGFLISKETLSV----RMLDDSRDPT--PLLKEIRDDKVSTIIIDANASISHLILRKAS 231

Query: 225 TIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKE 284
            +G     Y YI+  + F    L  I    +N+ GF + +       +F+   +    + 
Sbjct: 232 ELGMTSAFYKYILTTMDFPILHLDGIVEDSSNILGFSMFNTSHPFYPEFVRSLNMSWREN 291

Query: 285 YPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEI 344
              +       ++AL +DAV V+  A R L + + EI  +  A       A  W  G  +
Sbjct: 292 CEASTYLGPALSAALMFDAVHVVVSAVRELNRSQ-EIGVKPLA----CTSANIWPHGTSL 346

Query: 345 ERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPS 404
              L+ V+ +GL+G ++F+  G+R NYT+ I+E    G R+IG W     + +  T L  
Sbjct: 347 MNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKSRQGHREIGVWYSNRTLAMNATTLDI 406

Query: 405 GNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLT 464
            N +  L NKT+VVTTILE+PYVM + N + L GNER+EG+CVD+  E+A+   F+Y+L 
Sbjct: 407 -NLSQTLANKTLVVTTILENPYVMRRPNFQALSGNERFEGFCVDMLRELAELLRFRYRLR 465

Query: 465 IVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIM 524
           +V DG YGA + +   W GMVGEL+  KAD+A+A  TIT  RE+VIDFSKPFM+LGISI+
Sbjct: 466 LVEDGLYGAPEPNGS-WTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISIL 524

Query: 525 IKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQ 584
            +     KPG FSFLDP +  +W+ ++ AY+ VS VLFL +R SPYEW+          +
Sbjct: 525 YRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPH--PCLRAR 582

Query: 585 SSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAF 644
                N++ + NSLWF +G FM+QG +I PR+LS R V GVWW FTLIIISSYTANLAAF
Sbjct: 583 PHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAF 642

Query: 645 LTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFV 704
           LTV+RM  P+ESA+DL+ QT I YGT+ +GST  FF+ S+   + +MW YM+S +PSVFV
Sbjct: 643 LTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQPSVFV 702

Query: 705 RTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLR 764
           ++T EG+ARV  S  +YA+LLESTMNEY  +R  C+  ++GG LD+KGYGI  P GS  R
Sbjct: 703 KSTEEGIARVLNS--RYAFLLESTMNEY-HRRLNCNLTQIGGLLDTKGYGIGMPLGSPFR 759

Query: 765 TPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGL 824
             + LA+L+L E   L+ LK KWW + G C  ++     +   L + N+ G+F +L+ GL
Sbjct: 760 DEITLAILQLQENNRLEILKRKWW-EGGRCPKEED---HRAKGLGMENIGGIFIVLICGL 815

Query: 825 GLAMLVALIEFCYKSRAEAKRMKVA 849
            +A+ VA++EF + +R  A+  +V+
Sbjct: 816 IIAVFVAVMEFIWSTRRSAESEEVS 840


>gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [Homo
           sapiens]
          Length = 1009

 Score =  350 bits (897), Expect = 4e-96
 Identities = 256/859 (29%), Positives = 419/859 (48%), Gaps = 71/859 (8%)

Query: 27  IQIGGLFPRGADQEYSAFRVGMVQFSTSEF-----RLTPHIDNLEVANSFAVTNAFCSQF 81
           I IG +F   A ++   F++ +   S ++      ++T  I  +E  N F      C   
Sbjct: 24  IHIGAIFEENAAKDDRVFQLAVSDLSLNDDILQSEKITYSIKVIEANNPFQAVQEACDLM 83

Query: 82  SRGVYAIFGFYDKKSVNTITSFCGTLHVSFI--------TPSF-----PTDGTHPFVIQM 128
           ++G+ A+       S N + S    +H+  +        +P       P+     + +  
Sbjct: 84  TQGILALVTSTGCASANALQSLTDAMHIPHLFVQRNPGGSPRTACHLNPSPDGEAYTLAS 143

Query: 129 RPD--LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVG-NINN 185
           RP   L   +L L+   +W KF   YDS+  +  LQ+ LD A+     V+   V  NI++
Sbjct: 144 RPPVRLNDVMLRLVTELRWQKFVMFYDSEYDIRGLQSFLDQASRLGLDVSLQKVDKNISH 203

Query: 186 DKKDEMYRSLFQDLELKKE-------RRVILDCERDKVNDIVDQVITIGKHVKGYHYIIA 238
                ++ SLF  ++ ++        RR IL       +  +++ +      K  H++  
Sbjct: 204 -----VFTSLFTTMKTEELNRYRDTLRRAILLLSPQGAHSFINEAVETNLASKDSHWVFV 258

Query: 239 NLGFTDGDLLKIQFG--GANVSGFQIVDY--DDSLVSKFIERWSTLEEKEYPGAHTTTIK 294
           N   +D ++L +     G      QI     D+   ++   R S+L      G +   ++
Sbjct: 259 NEEISDPEILDLVHSALGRMTVVRQIFPSAKDNQKCTRNNHRISSLLCDPQEG-YLQMLQ 317

Query: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354
            ++   YD+V ++  AF    + R   S      +C+     PW  G  +   +K+  + 
Sbjct: 318 ISNLYLYDSVLMLANAFHRKLEDRKWHSMASL--NCIRKSTKPWNGGRSMLDTIKKGHIT 375

Query: 355 GLSGNIKFDQNGKRINYTINIM-----ELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTS 409
           GL+G ++F ++         I+     E      RK+  W     +  +L E P G+   
Sbjct: 376 GLTGVMEFREDSSNPYVQFEILGTTYSETFGKDMRKLATWDSEKGLNGSLQERPMGSRLQ 435

Query: 410 GLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDG 469
           GL   T+ V T+LE P+VM+ +N  +L   +RY+G+ +D+   +AK  GFKY++    DG
Sbjct: 436 GL---TLKVVTVLEEPFVMVAEN--ILGQPKRYKGFSIDVLDALAKALGFKYEIYQAPDG 490

Query: 470 KYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQ 529
           +YG +  +T  WNGM+GEL+  +AD+AI+ +TIT  RE V+DFSK +M   + I+IKKP+
Sbjct: 491 RYGHQLHNTS-WNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYSVGILIKKPE 549

Query: 530 KSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSEST 589
           + K  +FS   P  + +W CI  A   V V++F+++R           +   + + S S 
Sbjct: 550 E-KISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVR-----AQSAAQPRPSASA 603

Query: 590 NEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVER 649
               + +++W   GAF++QG + S  S++ RIV G WW FTLI+ SSYTANLAAFLTV R
Sbjct: 604 T---LHSAIWIVYGAFVQQGGESSVNSMAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSR 660

Query: 650 MVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRR------SKIAVFDKMW-TYMRSAEPSV 702
           M +PI + +DLSKQ E++YGT+   +  E+FR        + + F ++W T  ++     
Sbjct: 661 MDNPIRTFQDLSKQVEMSYGTVRDSAVYEYFRAKGTNPLEQDSTFAELWRTISKNGGADN 720

Query: 703 FVRTTAEGVARVRKSKGKYAYLLESTMNEYIE-QRKPCDTMKVGGNLDSKGYGIATPKGS 761
            V + +EG+ + +  KG YA+L +  + EY       C    +G ++ SKGYGIA   GS
Sbjct: 721 CVSSPSEGIRKAK--KGNYAFLWDVAVVEYAALTDDDCSVTVIGNSISSKGYGIALQHGS 778

Query: 762 SLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKT-SALSLSNVAGVFYIL 820
             R   +  +L+L + G LD LK KWW   G C      S +    +L L + AGVF IL
Sbjct: 779 PYRDLFSQRILELQDTGDLDVLKQKWWPHMGRCDLTSHASAQADGKSLKLHSFAGVFCIL 838

Query: 821 VGGLGLAMLVALIEFCYKS 839
             GL LA LVA +E  + S
Sbjct: 839 AIGLLLACLVAALELWWNS 857


>gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens]
          Length = 1007

 Score =  347 bits (889), Expect = 4e-95
 Identities = 242/863 (28%), Positives = 419/863 (48%), Gaps = 80/863 (9%)

Query: 27  IQIGGLFPRGADQEYSAFRVGMVQFSTSEF-----RLTPHIDNLEVANSFAVTNAFCSQF 81
           I IG +F   A ++   FR  +   + +E      ++T  +  ++  N F      C   
Sbjct: 27  IHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQEACELM 86

Query: 82  SRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGT-------------HPFVIQM 128
           ++G+ A+       S  ++ S    +H+  +     T GT               + + +
Sbjct: 87  NQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYTLSV 146

Query: 129 RPD--LKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINND 186
           RP   L   +L ++  Y W KF   YDS+  +  +Q  LD  +++   V    V N  N 
Sbjct: 147 RPPVYLHDVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQKVENNIN- 205

Query: 187 KKDEMYRSLFQDLELKKE-------RRVILDCERDKVNDIVDQVITIGKHVKGYHYIIAN 239
              +M  +LF  + +++        RR IL          + +V+         H+II N
Sbjct: 206 ---KMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFITEVVETNLVAFDCHWIIIN 262

Query: 240 LGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERW--------STLEEKEYPGAHTT 291
               D D+ ++     ++    I+     +     +R         STL + + P A   
Sbjct: 263 EEINDVDVQELV--RRSIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDPFAQNM 320

Query: 292 TIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQV 351
            I  ++   YD V ++  AF    + R   S    +  C+   + PW  G  +   +K+ 
Sbjct: 321 EI--SNLYIYDTVLLLANAFHKKLEDRKWHSMASLS--CIRKNSKPWQGGRSMLETIKKG 376

Query: 352 QVEGLSGNIKFDQNGKRINYTINIM-----ELKTNGPRKIGYWSEVDKMVVTLTELPSGN 406
            V GL+G ++F +NG   N    I+     E    G RK+G W+ V  +  +LT+    N
Sbjct: 377 GVSGLTGELEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTDKKLEN 436

Query: 407 DTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIV 466
           +  G+    + V T+LE P+VM+ +N  +L   ++Y+G+ +D+   ++ + GF Y++ + 
Sbjct: 437 NMRGV---VLRVVTVLEEPFVMVSEN--VLGKPKKYQGFSIDVLDALSNYLGFNYEIYVA 491

Query: 467 GDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIK 526
            D KYG+   D   WNG+VGELV+ +ADI I+ LTIT  RE V+DF+  +M   + ++++
Sbjct: 492 PDHKYGSPQEDGT-WNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLR 550

Query: 527 KPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSS 586
           + +K+   +F+ L P    +W CI    + V ++++L++  +P        + G  T ++
Sbjct: 551 RAEKTVD-MFACLAPFDLSLWACIAGTVLLVGLLVYLLNWLNP-----PRLQMGSMTSTT 604

Query: 587 ESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLT 646
                  ++NS+WF  G+F++QG ++   +L+ R++ G WW F LI+ISSYTANLAAFLT
Sbjct: 605 -------LYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLAAFLT 657

Query: 647 VERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKI------AVFDKMWTYMRSAEP 700
           + R+ S I+S +DLSKQTEI YGT+   +  E  R   +      +++ +MW  +  +  
Sbjct: 658 ITRIESSIQSLQDLSKQTEIPYGTVLDSAVYEHVRMKGLNPFERDSMYSQMWRMINRSNG 717

Query: 701 SVFVRTTAEGVARVRKSK-GKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGIATP 758
           S       E  A ++K K G YA++ ++ + EY+    P C    +G  +  +GYGIA  
Sbjct: 718 S--ENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTIGNTVADRGYGIALQ 775

Query: 759 KGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDS-GSKEKTSALSLSNVAGVF 817
            GS  R   +  +L+L + G +D LK+KWW   G+C    S  +K+K  AL + + AGVF
Sbjct: 776 HGSPYRDVFSQRILELQQNGDMDILKHKWWPKNGQCDLYSSVDTKQKGGALDIKSFAGVF 835

Query: 818 YILVGGLGLAMLVALIEFCYKSR 840
            IL  G+ L+  +A++E  +  R
Sbjct: 836 CILAAGIVLSCFIAMLETWWNKR 858


>gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens]
          Length = 885

 Score =  235 bits (599), Expect = 2e-61
 Identities = 181/615 (29%), Positives = 306/615 (49%), Gaps = 85/615 (13%)

Query: 294 KYTSALTYDAVQVMTEAFRNL-RKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQ 352
           K  SA   DAV V+ +A   L  K+ I    RG    C+ N  + W  G   +R L   +
Sbjct: 275 KNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 329

Query: 353 -VEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEV-----DKMVVTL---TELP 403
             +G++G ++F+++G R     +IM L+     ++G ++       D+ ++     TE P
Sbjct: 330 YADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKP 389

Query: 404 SGNDTSGLENKTVVVTTILESPYVMMKKN-------------------------HEMLEG 438
            G   S      + + TI + P+V +K                           ++   G
Sbjct: 390 RGYQMS----TRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPG 445

Query: 439 NERYE------GYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD----ADTKIWNGMVGEL 488
           + R+       G+C+DL  ++A+   F Y++ +V DGK+G ++    ++ K WNGM+GEL
Sbjct: 446 SPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGEL 505

Query: 489 VYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM 548
           + G+AD+ +APLTI   R + I+FSKPF   G++I++KK +  +  + SF+ P    +W+
Sbjct: 506 LSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWL 564

Query: 549 CIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNE--FGIFNSLWFSLGAFM 606
            +  +   V+V+L+L+ RFSP+         GR   +SE   E    + +++WFS G  +
Sbjct: 565 LVGLSVHVVAVMLYLLDRFSPF---------GRFKVNSEEEEEDALTLSSAMWFSWGVLL 615

Query: 607 RQGC-DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED---LSK 662
             G  + +PRS S RI+G VW  F +II++SYTANLAAFL ++R    I    D    + 
Sbjct: 616 NSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNP 675

Query: 663 QTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYA 722
             +  Y T+   S   +FRR        M+ +M          + AE +  VR +K  +A
Sbjct: 676 SDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHA 728

Query: 723 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDK 782
           ++ +S + E+ E  + CD +  G      G+GI   K S  +  V+L++LK  E G ++ 
Sbjct: 729 FIWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMED 787

Query: 783 LKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAE 842
           L +K W    EC ++ +      + L+  N+AGVF ++ GG+   + +  IE  YK   +
Sbjct: 788 L-DKTWVRYQECDSRSNA----PATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKD 842

Query: 843 AKR--MKVAKNAQNI 855
           A+R  M++A  A N+
Sbjct: 843 ARRKQMQLAFAAVNV 857


>gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens]
          Length = 938

 Score =  235 bits (599), Expect = 2e-61
 Identities = 181/615 (29%), Positives = 306/615 (49%), Gaps = 85/615 (13%)

Query: 294 KYTSALTYDAVQVMTEAFRNL-RKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQ 352
           K  SA   DAV V+ +A   L  K+ I    RG    C+ N  + W  G   +R L   +
Sbjct: 275 KNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 329

Query: 353 -VEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEV-----DKMVVTL---TELP 403
             +G++G ++F+++G R     +IM L+     ++G ++       D+ ++     TE P
Sbjct: 330 YADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKP 389

Query: 404 SGNDTSGLENKTVVVTTILESPYVMMKKN-------------------------HEMLEG 438
            G   S      + + TI + P+V +K                           ++   G
Sbjct: 390 RGYQMS----TRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPG 445

Query: 439 NERYE------GYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD----ADTKIWNGMVGEL 488
           + R+       G+C+DL  ++A+   F Y++ +V DGK+G ++    ++ K WNGM+GEL
Sbjct: 446 SPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGEL 505

Query: 489 VYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM 548
           + G+AD+ +APLTI   R + I+FSKPF   G++I++KK +  +  + SF+ P    +W+
Sbjct: 506 LSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWL 564

Query: 549 CIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNE--FGIFNSLWFSLGAFM 606
            +  +   V+V+L+L+ RFSP+         GR   +SE   E    + +++WFS G  +
Sbjct: 565 LVGLSVHVVAVMLYLLDRFSPF---------GRFKVNSEEEEEDALTLSSAMWFSWGVLL 615

Query: 607 RQGC-DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED---LSK 662
             G  + +PRS S RI+G VW  F +II++SYTANLAAFL ++R    I    D    + 
Sbjct: 616 NSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNP 675

Query: 663 QTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYA 722
             +  Y T+   S   +FRR        M+ +M          + AE +  VR +K  +A
Sbjct: 676 SDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHA 728

Query: 723 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDK 782
           ++ +S + E+ E  + CD +  G      G+GI   K S  +  V+L++LK  E G ++ 
Sbjct: 729 FIWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMED 787

Query: 783 LKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAE 842
           L +K W    EC ++ +      + L+  N+AGVF ++ GG+   + +  IE  YK   +
Sbjct: 788 L-DKTWVRYQECDSRSNA----PATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKD 842

Query: 843 AKR--MKVAKNAQNI 855
           A+R  M++A  A N+
Sbjct: 843 ARRKQMQLAFAAVNV 857


>gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens]
          Length = 901

 Score =  235 bits (599), Expect = 2e-61
 Identities = 181/615 (29%), Positives = 306/615 (49%), Gaps = 85/615 (13%)

Query: 294 KYTSALTYDAVQVMTEAFRNL-RKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQ 352
           K  SA   DAV V+ +A   L  K+ I    RG    C+ N  + W  G   +R L   +
Sbjct: 275 KNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 329

Query: 353 -VEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEV-----DKMVVTL---TELP 403
             +G++G ++F+++G R     +IM L+     ++G ++       D+ ++     TE P
Sbjct: 330 YADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKP 389

Query: 404 SGNDTSGLENKTVVVTTILESPYVMMKKN-------------------------HEMLEG 438
            G   S      + + TI + P+V +K                           ++   G
Sbjct: 390 RGYQMS----TRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPG 445

Query: 439 NERYE------GYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD----ADTKIWNGMVGEL 488
           + R+       G+C+DL  ++A+   F Y++ +V DGK+G ++    ++ K WNGM+GEL
Sbjct: 446 SPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGEL 505

Query: 489 VYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM 548
           + G+AD+ +APLTI   R + I+FSKPF   G++I++KK +  +  + SF+ P    +W+
Sbjct: 506 LSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWL 564

Query: 549 CIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNE--FGIFNSLWFSLGAFM 606
            +  +   V+V+L+L+ RFSP+         GR   +SE   E    + +++WFS G  +
Sbjct: 565 LVGLSVHVVAVMLYLLDRFSPF---------GRFKVNSEEEEEDALTLSSAMWFSWGVLL 615

Query: 607 RQGC-DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED---LSK 662
             G  + +PRS S RI+G VW  F +II++SYTANLAAFL ++R    I    D    + 
Sbjct: 616 NSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNP 675

Query: 663 QTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYA 722
             +  Y T+   S   +FRR        M+ +M          + AE +  VR +K  +A
Sbjct: 676 SDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHA 728

Query: 723 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDK 782
           ++ +S + E+ E  + CD +  G      G+GI   K S  +  V+L++LK  E G ++ 
Sbjct: 729 FIWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMED 787

Query: 783 LKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAE 842
           L +K W    EC ++ +      + L+  N+AGVF ++ GG+   + +  IE  YK   +
Sbjct: 788 L-DKTWVRYQECDSRSNA----PATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKD 842

Query: 843 AKR--MKVAKNAQNI 855
           A+R  M++A  A N+
Sbjct: 843 ARRKQMQLAFAAVNV 857


>gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor
           [Homo sapiens]
          Length = 1484

 Score =  187 bits (475), Expect = 4e-47
 Identities = 183/740 (24%), Positives = 329/740 (44%), Gaps = 100/740 (13%)

Query: 136 LLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKK---WQVTAINVGNINNDKKDEMY 192
           +L+++E Y W  F+ +     G       + S  E     W++  + + +++ D  D   
Sbjct: 157 MLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDSKI 216

Query: 193 RSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQF 252
           ++  + L+      ++L C +++   I +   ++G    GY +I+ +L   D D +  +F
Sbjct: 217 QNQLKKLQ---SPIILLYCTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGDTDTVPAEF 273

Query: 253 GGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFR 312
               +S    V YD+         W      +Y            A   D + ++T A  
Sbjct: 274 PTGLIS----VSYDE---------W------DYG---------LPARVRDGIAIITTAAS 305

Query: 313 NLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYT 372
           ++  +   I    ++  C         Q   + R L  V  EG   N+ F ++G +++  
Sbjct: 306 DMLSEHSFIPEPKSS--CYNTHEKRIYQSNMLNRYLINVTFEGR--NLSFSEDGYQMHPK 361

Query: 373 INIMEL-KTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKK 431
           + I+ L K     ++G W +    +          +T   E+  + + T+ E+P+V+++ 
Sbjct: 362 LVIILLNKERKWERVGKWKDKSLQMKYYVWPRMCPETEEQEDDHLSIVTLEEAPFVIVES 421

Query: 432 ---------------NHEMLEGNERYE----------GYCVDLAAEIAKHCGFKYKLTIV 466
                             ++  N+  E          G+C+D+  +I+K   F Y L +V
Sbjct: 422 VDPLSGTCMRNTVPCQKRIVTENKTDEEPGYIKKCCKGFCIDILKKISKSVKFTYDLYLV 481

Query: 467 GDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIK 526
            +GK+G +   T  WNGM+GE+V  +A +A+  LTI   R EV+DFS PF+  GIS+M+ 
Sbjct: 482 TNGKHGKKINGT--WNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVS 539

Query: 527 KPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQS 585
           +         +FL+P + ++W M  V   I  +V +F+   FSP  ++     DGRE   
Sbjct: 540 R-SNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYN-RCLADGREPGG 597

Query: 586 SESTNEFGIFNSLWFSLGAFMRQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAF 644
                 F I  ++W   G        + +P+  + +I+  VW FF +I ++SYTANLAAF
Sbjct: 598 P----SFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAF 653

Query: 645 LTVERMVSPIESAEDLSKQ------TEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSA 698
           +  E  V  +    D   Q          +GT+ +GST+   R +    + +M  YM   
Sbjct: 654 MIQEEYVDQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNN----YAEMHAYM--- 706

Query: 699 EPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGI 755
               F +   +      K+    A++ ++ +  Y+  R + C  + +G      S GYGI
Sbjct: 707 --GKFNQRGVDDALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGI 764

Query: 756 ATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAG 815
           A  K S  +  V+LA+L+L   G +++L+  W    G C   +  ++  +S L + N+AG
Sbjct: 765 AIQKDSGWKRQVDLAILQLFGDGEMEELEALWL--TGIC--HNEKNEVMSSQLDIDNMAG 820

Query: 816 VFYILVGGLGLAMLVALIEF 835
           VFY+    LG AM ++LI F
Sbjct: 821 VFYM----LGAAMALSLITF 836


>gi|55770854 N-methyl-D-aspartate receptor subunit 2C precursor
           [Homo sapiens]
          Length = 1233

 Score =  182 bits (462), Expect = 1e-45
 Identities = 191/792 (24%), Positives = 335/792 (42%), Gaps = 103/792 (13%)

Query: 82  SRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIE 141
           +  V  I  F   ++   I S  G   V  +TP  P        + +   L+  L  ++E
Sbjct: 101 TEAVAQILDFISSQTHVPILSISGGSAV-VLTPKEPGSAFLQLGVSLEQQLQ-VLFKVLE 158

Query: 142 YYQWDKFAYLYDSDRG----LSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQ 197
            Y W  FA +     G    L  ++AV D A+   W++  +    +         + L +
Sbjct: 159 EYDWSAFAVITSLHPGHALFLEGVRAVAD-ASHVSWRLLDVVTLELGPGGPRARTQRLLR 217

Query: 198 DLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANV 257
            L+       +  C R++   +  +    G    G+ +++ NL     D        A  
Sbjct: 218 QLDAPV---FVAYCSREEAEVLFAEAAQAGLVGPGHVWLVPNLALGSTD--------APP 266

Query: 258 SGFQIVDYDDSLVSKFIERWS-TLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRK 316
           + F +      L+S   E W  +L +K                  D V ++     +  +
Sbjct: 267 ATFPV-----GLISVVTESWRLSLRQK----------------VRDGVAILALGAHSYWR 305

Query: 317 QRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIM 376
           Q   +     AGDC  +P           R L  V  EG   +  F   G  +  T+ ++
Sbjct: 306 QHGTLP--APAGDCRVHPGPVSPAREAFYRHLLNVTWEGR--DFSFSPGGYLVQPTMVVI 361

Query: 377 ELKTNGP-RKIGYWSE-VDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKK--- 431
            L  +     +G W   V  M   +    S +    ++++ + V T+ E P+V+++    
Sbjct: 362 ALNRHRLWEMVGRWEHGVLYMKYPVWPRYSASLQPVVDSRHLTVATLEERPFVIVESPDP 421

Query: 432 ----------------NHEMLEGNER------YEGYCVDLAAEIAKHCGFKYKLTIVGDG 469
                           NH    G+         +G+C+D+  ++A+   F Y L +V +G
Sbjct: 422 GTGGCVPNTVPCRRQSNHTFSSGDVAPYTKLCCKGFCIDILKKLARVVKFSYDLYLVTNG 481

Query: 470 KYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQ 529
           K+G R     +WNGM+GE+ Y +AD+AI  LTI   R E++DFS PF+  GIS+M+ +  
Sbjct: 482 KHGKRVRG--VWNGMIGEVYYKRADMAIGSLTINEERSEIVDFSVPFVETGISVMVAR-S 538

Query: 530 KSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSES 588
                  +FL+P +  +W M  V     V++ +F+   FSP  ++ +    G+++     
Sbjct: 539 NGTVSPSAFLEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYN-QNLTRGKKSGGP-- 595

Query: 589 TNEFGIFNSLWFSLGAFMRQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 647
              F I  S+W            I +PR  + +I+  VW FF +I ++SYTANLAAF+  
Sbjct: 596 --AFTIGKSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQ 653

Query: 648 ERMVSPIESAEDLSKQ------TEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPS 701
           E+ +  +    D   Q          +GT+ +GST+   R +    +  M T+M      
Sbjct: 654 EQYIDTVSGLSDKKFQRPQDQYPPFRFGTVPNGSTERNIRSN----YRDMHTHMVK---- 705

Query: 702 VFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATP 758
            F + + E      K     A++ ++ +  Y+  + + C  + +G      + GYGIA  
Sbjct: 706 -FNQRSVEDALTSLKMGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQ 764

Query: 759 KGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFY 818
           K S  +  ++LA+L+    G   KL+  W    G C  ++  ++  +S L + N+AGVFY
Sbjct: 765 KDSHWKRAIDLALLQFLGDGETQKLETVWL--SGIC--QNEKNEVMSSKLDIDNMAGVFY 820

Query: 819 ILVGGLGLAMLV 830
           +L+  +GLA+LV
Sbjct: 821 MLLVAMGLALLV 832


>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor
           [Homo sapiens]
          Length = 1336

 Score =  175 bits (444), Expect = 1e-43
 Identities = 121/400 (30%), Positives = 206/400 (51%), Gaps = 34/400 (8%)

Query: 443 EGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTI 502
           +G+C+D+   +A   GF Y L +V +GK+G +     +WNGM+GE+ Y +AD+AI  LTI
Sbjct: 485 KGFCIDILKRLAHTIGFSYDLYLVTNGKHGKKIDG--VWNGMIGEVFYQRADMAIGSLTI 542

Query: 503 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVL 561
              R E++DFS PF+  GIS+M+ +         +FL+P +  +W M  V     V+V +
Sbjct: 543 NEERSEIVDFSVPFVETGISVMVAR-SNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTV 601

Query: 562 FLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDI-SPRSLSGR 620
           F+    SP  ++         T      + F I  S+W            + +PR  + +
Sbjct: 602 FIFEYLSPVGYNR-----SLATGKRPGGSTFTIGKSIWLLWALVFNNSVPVENPRGTTSK 656

Query: 621 IVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQ------TEIAYGTLDSG 674
           I+  VW FF +I ++SYTANLAAF+  E  V  +    D   Q        + +GT+ +G
Sbjct: 657 IMVLVWAFFAVIFLASYTANLAAFMIQEEYVDTVSGLSDRKFQRPQEQYPPLKFGTVPNG 716

Query: 675 STKEFFRRSKIAVFDKMWTYM-RSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYI 733
           ST++  R +    +  M +YM R  +P V      E + +++  K   A++ ++ +  Y+
Sbjct: 717 STEKNIRSN----YPDMHSYMVRYNQPRV-----EEALTQLKAGK-LDAFIYDAAVLNYM 766

Query: 734 EQR-KPCDTMKVGGN--LDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYD 790
            ++ + C  + +G      + GYGIA  KGS  + P++LA+L+      ++ L+  W   
Sbjct: 767 ARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIEMLERLWL-- 824

Query: 791 KGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLV 830
            G C   +   +  +S L + N+AGVFY+L+  +GL++LV
Sbjct: 825 SGIC--HNDKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLV 862


>gi|197313638 N-methyl-D-aspartate receptor subunit 2A isoform 2
           precursor [Homo sapiens]
          Length = 1281

 Score =  172 bits (435), Expect = 2e-42
 Identities = 172/676 (25%), Positives = 308/676 (45%), Gaps = 68/676 (10%)

Query: 189 DEMYRSLFQDLELKKERR--VILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGD 246
           D  +      ++LKK     ++L C +D+   I+ +  ++G     + +I+ +L   + +
Sbjct: 207 DTSFEDAKTQVQLKKIHSSVILLYCSKDEAVLILSEARSLGLTGYDFFWIVPSLVSGNTE 266

Query: 247 LLKIQFGGANVSGFQIVDYDDSLVSKFIERWS-TLEEKEYPGAHTTTIKYTSALTYDAVQ 305
           L+  +F     SG   V YDD         W  +LE +   G    T   +S L   +  
Sbjct: 267 LIPKEFP----SGLISVSYDD---------WDYSLEARVRDGIGILTTAASSMLEKFSYI 313

Query: 306 VMTEAFRNLRKQRIEISRRGNAGDCLANPAVPW-GQGVEIERALKQVQ----VEGLSGNI 360
              +A    + +R E+         + N  V W G+ +       QV     V  L+ + 
Sbjct: 314 PEAKASCYGQMERPEVPMH-TLHPFMVN--VTWDGKDLSFTEEGYQVHPRLVVIVLNKDR 370

Query: 361 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDK--MVVTLTELPSG--NDTSGLENKTV 416
           ++++ GK  N+T+++        +        D    +VTL E P     D   L  +T 
Sbjct: 371 EWEKVGKWENHTLSLRHAVWPRYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPL-TETC 429

Query: 417 VVTTILESPYVMMKKN-HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 475
           V  T+    +V +  + +E +   +  +G+C+D+  ++++   F Y L +V +GK+G + 
Sbjct: 430 VRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKV 489

Query: 476 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 535
               +WNGM+GE+VY +A +A+  LTI   R EV+DFS PF+  GIS+M+ +        
Sbjct: 490 --NNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSR-SNGTVSP 546

Query: 536 FSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGI 594
            +FL+P +  +W M  V   I  ++ +F+   FSP  ++      G+          F I
Sbjct: 547 SAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYN-RNLAKGKAPHGP----SFTI 601

Query: 595 FNSLWFSLGAFMRQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 653
             ++W   G        + +P+  + +I+  VW FF +I ++SYTANLAAF+  E  V  
Sbjct: 602 GKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQ 661

Query: 654 IESAEDLSKQ------TEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 707
           +    D   Q          +GT+ +GST+   R +    +  M  YM         +  
Sbjct: 662 VTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNN----YPYMHQYM--------TKFN 709

Query: 708 AEGV--ARVRKSKGKY-AYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGS 761
            +GV  A V    GK  A++ ++ +  Y   R + C  + +G      + GYGIA  KGS
Sbjct: 710 QKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGS 769

Query: 762 SLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILV 821
             +  ++LA+L+    G +++L+  W    G C   +  ++  +S L + N+AGVFY+L 
Sbjct: 770 PWKRQIDLALLQFVGDGEMEELETLWL--TGIC--HNEKNEVMSSQLDIDNMAGVFYMLA 825

Query: 822 GGLGLAMLVALIEFCY 837
             + L+++  + E  +
Sbjct: 826 AAMALSLITFIWEHLF 841


>gi|197313636 N-methyl-D-aspartate receptor subunit 2A isoform 1
           precursor [Homo sapiens]
          Length = 1464

 Score =  172 bits (435), Expect = 2e-42
 Identities = 172/676 (25%), Positives = 308/676 (45%), Gaps = 68/676 (10%)

Query: 189 DEMYRSLFQDLELKKERR--VILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGD 246
           D  +      ++LKK     ++L C +D+   I+ +  ++G     + +I+ +L   + +
Sbjct: 207 DTSFEDAKTQVQLKKIHSSVILLYCSKDEAVLILSEARSLGLTGYDFFWIVPSLVSGNTE 266

Query: 247 LLKIQFGGANVSGFQIVDYDDSLVSKFIERWS-TLEEKEYPGAHTTTIKYTSALTYDAVQ 305
           L+  +F     SG   V YDD         W  +LE +   G    T   +S L   +  
Sbjct: 267 LIPKEFP----SGLISVSYDD---------WDYSLEARVRDGIGILTTAASSMLEKFSYI 313

Query: 306 VMTEAFRNLRKQRIEISRRGNAGDCLANPAVPW-GQGVEIERALKQVQ----VEGLSGNI 360
              +A    + +R E+         + N  V W G+ +       QV     V  L+ + 
Sbjct: 314 PEAKASCYGQMERPEVPMH-TLHPFMVN--VTWDGKDLSFTEEGYQVHPRLVVIVLNKDR 370

Query: 361 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDK--MVVTLTELPSG--NDTSGLENKTV 416
           ++++ GK  N+T+++        +        D    +VTL E P     D   L  +T 
Sbjct: 371 EWEKVGKWENHTLSLRHAVWPRYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPL-TETC 429

Query: 417 VVTTILESPYVMMKKN-HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 475
           V  T+    +V +  + +E +   +  +G+C+D+  ++++   F Y L +V +GK+G + 
Sbjct: 430 VRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKV 489

Query: 476 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 535
               +WNGM+GE+VY +A +A+  LTI   R EV+DFS PF+  GIS+M+ +        
Sbjct: 490 --NNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSR-SNGTVSP 546

Query: 536 FSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGI 594
            +FL+P +  +W M  V   I  ++ +F+   FSP  ++      G+          F I
Sbjct: 547 SAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYN-RNLAKGKAPHGP----SFTI 601

Query: 595 FNSLWFSLGAFMRQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 653
             ++W   G        + +P+  + +I+  VW FF +I ++SYTANLAAF+  E  V  
Sbjct: 602 GKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQ 661

Query: 654 IESAEDLSKQ------TEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 707
           +    D   Q          +GT+ +GST+   R +    +  M  YM         +  
Sbjct: 662 VTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNN----YPYMHQYM--------TKFN 709

Query: 708 AEGV--ARVRKSKGKY-AYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGS 761
            +GV  A V    GK  A++ ++ +  Y   R + C  + +G      + GYGIA  KGS
Sbjct: 710 QKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGS 769

Query: 762 SLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILV 821
             +  ++LA+L+    G +++L+  W    G C   +  ++  +S L + N+AGVFY+L 
Sbjct: 770 PWKRQIDLALLQFVGDGEMEELETLWL--TGIC--HNEKNEVMSSQLDIDNMAGVFYMLA 825

Query: 822 GGLGLAMLVALIEFCY 837
             + L+++  + E  +
Sbjct: 826 AAMALSLITFIWEHLF 841


>gi|4504125 N-methyl-D-aspartate receptor subunit 2A isoform 1
           precursor [Homo sapiens]
          Length = 1464

 Score =  172 bits (435), Expect = 2e-42
 Identities = 172/676 (25%), Positives = 308/676 (45%), Gaps = 68/676 (10%)

Query: 189 DEMYRSLFQDLELKKERR--VILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGD 246
           D  +      ++LKK     ++L C +D+   I+ +  ++G     + +I+ +L   + +
Sbjct: 207 DTSFEDAKTQVQLKKIHSSVILLYCSKDEAVLILSEARSLGLTGYDFFWIVPSLVSGNTE 266

Query: 247 LLKIQFGGANVSGFQIVDYDDSLVSKFIERWS-TLEEKEYPGAHTTTIKYTSALTYDAVQ 305
           L+  +F     SG   V YDD         W  +LE +   G    T   +S L   +  
Sbjct: 267 LIPKEFP----SGLISVSYDD---------WDYSLEARVRDGIGILTTAASSMLEKFSYI 313

Query: 306 VMTEAFRNLRKQRIEISRRGNAGDCLANPAVPW-GQGVEIERALKQVQ----VEGLSGNI 360
              +A    + +R E+         + N  V W G+ +       QV     V  L+ + 
Sbjct: 314 PEAKASCYGQMERPEVPMH-TLHPFMVN--VTWDGKDLSFTEEGYQVHPRLVVIVLNKDR 370

Query: 361 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDK--MVVTLTELPSG--NDTSGLENKTV 416
           ++++ GK  N+T+++        +        D    +VTL E P     D   L  +T 
Sbjct: 371 EWEKVGKWENHTLSLRHAVWPRYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPL-TETC 429

Query: 417 VVTTILESPYVMMKKN-HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARD 475
           V  T+    +V +  + +E +   +  +G+C+D+  ++++   F Y L +V +GK+G + 
Sbjct: 430 VRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKV 489

Query: 476 ADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 535
               +WNGM+GE+VY +A +A+  LTI   R EV+DFS PF+  GIS+M+ +        
Sbjct: 490 --NNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSR-SNGTVSP 546

Query: 536 FSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGI 594
            +FL+P +  +W M  V   I  ++ +F+   FSP  ++      G+          F I
Sbjct: 547 SAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYN-RNLAKGKAPHGP----SFTI 601

Query: 595 FNSLWFSLGAFMRQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 653
             ++W   G        + +P+  + +I+  VW FF +I ++SYTANLAAF+  E  V  
Sbjct: 602 GKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQ 661

Query: 654 IESAEDLSKQ------TEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT 707
           +    D   Q          +GT+ +GST+   R +    +  M  YM         +  
Sbjct: 662 VTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNN----YPYMHQYM--------TKFN 709

Query: 708 AEGV--ARVRKSKGKY-AYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGS 761
            +GV  A V    GK  A++ ++ +  Y   R + C  + +G      + GYGIA  KGS
Sbjct: 710 QKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGS 769

Query: 762 SLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILV 821
             +  ++LA+L+    G +++L+  W    G C   +  ++  +S L + N+AGVFY+L 
Sbjct: 770 PWKRQIDLALLQFVGDGEMEELETLWL--TGIC--HNEKNEVMSSQLDIDNMAGVFYMLA 825

Query: 822 GGLGLAMLVALIEFCY 837
             + L+++  + E  +
Sbjct: 826 AAMALSLITFIWEHLF 841


>gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
           [Homo sapiens]
          Length = 1043

 Score =  165 bits (417), Expect = 2e-40
 Identities = 119/401 (29%), Positives = 197/401 (49%), Gaps = 30/401 (7%)

Query: 444 GYCVDLAAEIAKHCGFKYKLTIVGDGKYGA-RDADTKIWNGMVGELVYGKADIAIAPLTI 502
           GYC+DL   +A+   F ++L +VGDGKYGA RD     W G+VG+L+ G+A +A+   +I
Sbjct: 478 GYCIDLLERLAEDTPFDFELYLVGDGKYGALRDGR---WTGLVGDLLAGRAHMAVTSFSI 534

Query: 503 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLF 562
              R +V+DF+ PF S  + IM++    + P + +F+ PL +  W       +GV   L 
Sbjct: 535 NSARSQVVDFTSPFFSTSLGIMVRARDTASP-IGAFMWPLHWSTW-------LGVFAALH 586

Query: 563 LVSRF-SPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRI 621
           L + F + YEW +      R    S   +     N  +  L  F R     +P+  +GR+
Sbjct: 587 LTALFLTVYEWRSPYGLTPRGRNRSTVFSYSSALNLCYAIL--FRRTVSSKTPKCPTGRL 644

Query: 622 VGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLS---KQTEIAYGTLDSGSTKE 678
           +  +W  F L+++SSYTANLAA +  ++    +    D           +GT+   S + 
Sbjct: 645 LMNLWAIFCLLVLSSYTANLAAVMVGDKTFEELSGIHDPKLHHPAQGFRFGTVWESSAEA 704

Query: 679 FFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKY-AYLLESTMNEY-IEQR 736
           + ++S    F  M  +MR         TT  GVA +     K  A++++ ++ +Y +   
Sbjct: 705 YIKKS----FPDMHAHMRRHS----APTTPRGVAMLTSDPPKLNAFIMDKSLLDYEVSID 756

Query: 737 KPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGA 796
             C  + VG     +GYGI  P+ S L + ++  + +    G +D L +K WY    CG 
Sbjct: 757 ADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDK-WYKMVPCGK 815

Query: 797 KDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 837
           +     E T  +S+ + AG+F +L  GLG A+L +L E  +
Sbjct: 816 RVFAVTE-TLQMSIYHFAGLFVLLCLGLGSALLSSLGEHAF 855


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,923,291
Number of Sequences: 37866
Number of extensions: 1234499
Number of successful extensions: 2952
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2753
Number of HSP's gapped (non-prelim): 47
length of query: 883
length of database: 18,247,518
effective HSP length: 111
effective length of query: 772
effective length of database: 14,044,392
effective search space: 10842270624
effective search space used: 10842270624
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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