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Search of human proteins with 7427519
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7427519 minichromosome maintenance complex component 6 [Homo
sapiens]
(821 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7427519 minichromosome maintenance complex component 6 [Homo ... 1622 0.0
gi|33356547 minichromosome maintenance complex component 2 [Homo... 322 1e-87
gi|33469968 minichromosome maintenance complex component 7 isofo... 319 6e-87
gi|33469919 minichromosome maintenance complex component 4 [Homo... 305 9e-83
gi|33469917 minichromosome maintenance complex component 4 [Homo... 305 9e-83
gi|33469922 minichromosome maintenance complex component 7 isofo... 299 8e-81
gi|6631095 minichromosome maintenance complex component 3 [Homo ... 297 2e-80
gi|23510448 minichromosome maintenance complex component 5 [Homo... 291 2e-78
gi|19923727 minichromosome maintenance complex component 8 isofo... 256 8e-68
gi|33469924 minichromosome maintenance complex component 8 isofo... 253 4e-67
gi|23397546 minichromosome maintenance complex component 9 [Homo... 109 9e-24
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 37 0.074
gi|50659082 suppressor of variegation 4-20 homolog 1 isoform 1 [... 35 0.22
gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1 [... 34 0.48
gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2 [... 34 0.48
gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3 [... 34 0.48
gi|56788364 tubulin, gamma complex associated protein 6 [Homo sa... 34 0.48
gi|33946313 ninein isoform 4 [Homo sapiens] 34 0.63
gi|33946321 ninein isoform 5 [Homo sapiens] 34 0.63
gi|148536871 ninein isoform 1 [Homo sapiens] 34 0.63
gi|148536869 ninein isoform 2 [Homo sapiens] 34 0.63
gi|239752405 PREDICTED: similar to cancer/testis antigen family ... 33 0.82
gi|209954823 minichromosome maintenance complex component-like i... 33 1.1
gi|209954821 minichromosome maintenance complex component-like i... 33 1.1
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens] 33 1.4
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 32 1.8
gi|115527120 nebulin [Homo sapiens] 32 1.8
gi|217416374 hypothetical protein LOC92749 [Homo sapiens] 32 1.8
gi|121949802 cancer/testis antigen family 47, member A1 [Homo sa... 32 3.1
gi|121949798 cancer/testis antigen family 47, member A2 [Homo sa... 32 3.1
>gi|7427519 minichromosome maintenance complex component 6 [Homo
sapiens]
Length = 821
Score = 1622 bits (4200), Expect = 0.0
Identities = 821/821 (100%), Positives = 821/821 (100%)
Query: 1 MDLAAAAEPGAGSQHLEVRDEVAEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNT 60
MDLAAAAEPGAGSQHLEVRDEVAEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNT
Sbjct: 1 MDLAAAAEPGAGSQHLEVRDEVAEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNT 60
Query: 61 LVVSFVDLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRKEIPLAKDFYVAFQDLPTR 120
LVVSFVDLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRKEIPLAKDFYVAFQDLPTR
Sbjct: 61 LVVSFVDLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRKEIPLAKDFYVAFQDLPTR 120
Query: 121 HKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNIC 180
HKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNIC
Sbjct: 121 HKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNIC 180
Query: 181 RNPVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGD 240
RNPVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGD
Sbjct: 181 RNPVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGD 240
Query: 241 KCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLA 300
KCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLA
Sbjct: 241 KCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLA 300
Query: 301 CCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHG 360
CCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHG
Sbjct: 301 CCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHG 360
Query: 361 NDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTS 420
NDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTS
Sbjct: 361 NDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTS 420
Query: 421 GKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQ 480
GKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQ
Sbjct: 421 GKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQ 480
Query: 481 TISITKAGVKATLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDEC 540
TISITKAGVKATLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDEC
Sbjct: 481 TISITKAGVKATLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDEC 540
Query: 541 NEVTDYAIARRIVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKH 600
NEVTDYAIARRIVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKH
Sbjct: 541 NEVTDYAIARRIVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKH 600
Query: 601 LRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVE 660
LRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVE
Sbjct: 601 LRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVE 660
Query: 661 TPDVNLDQEEEIQMEVDEGAGGINGHADSPAPVNGINGYNEDINQESAPKASLRLGFSEY 720
TPDVNLDQEEEIQMEVDEGAGGINGHADSPAPVNGINGYNEDINQESAPKASLRLGFSEY
Sbjct: 661 TPDVNLDQEEEIQMEVDEGAGGINGHADSPAPVNGINGYNEDINQESAPKASLRLGFSEY 720
Query: 721 CRISNLIVLHLRKVEEEEDESALKRSELVNWYLKEIESEIDSEEELINKKRIIEKVIHRL 780
CRISNLIVLHLRKVEEEEDESALKRSELVNWYLKEIESEIDSEEELINKKRIIEKVIHRL
Sbjct: 721 CRISNLIVLHLRKVEEEEDESALKRSELVNWYLKEIESEIDSEEELINKKRIIEKVIHRL 780
Query: 781 THYDHVLIELTQAGLKGSTEGSESYEEDPYLVVNPNYLLED 821
THYDHVLIELTQAGLKGSTEGSESYEEDPYLVVNPNYLLED
Sbjct: 781 THYDHVLIELTQAGLKGSTEGSESYEEDPYLVVNPNYLLED 821
>gi|33356547 minichromosome maintenance complex component 2 [Homo
sapiens]
Length = 904
Score = 322 bits (824), Expect = 1e-87
Identities = 212/660 (32%), Positives = 343/660 (51%), Gaps = 87/660 (13%)
Query: 30 FLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEFYRVYPY 89
F +FL S G + + ++ + R +LVV++ DL L+ + E
Sbjct: 199 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEA------- 251
Query: 90 LCRALKTFVKDRKEIPLA---------KDFYVAFQDLPTRHKIRELTSSRIGLLTRISGQ 140
L+ F + E+ LA +V LP ++R L + L R SG
Sbjct: 252 PAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGV 311
Query: 141 VVRTHPVHPELVSGTFLCLDCQTVIRDV-EQQFKYTQPNICRNPVCANRRRFLLDTNKSR 199
V V P+L + C C V+ + Q + +P C P C + F ++ ++
Sbjct: 312 VTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSC--PECQSAGPFEVNMEETI 369
Query: 200 FVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLST 259
+ ++Q++RIQE+ ++ G +PRS + IL A+ V+S + GD+ + TG
Sbjct: 370 YQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIY----------- 418
Query: 260 PGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDEE 319
+ ++ +G+ + V LA VA + + EL DE+
Sbjct: 419 ---HNNYDGSLNTANGFPV---------------FATVILANHVAKKDNKVAVGELTDED 460
Query: 320 QTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKT 379
+ + +S+D+ + + S+ P+I+G++++KRG+ L LFGG PK
Sbjct: 461 V--------------KMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKN 506
Query: 380 TGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEES 439
G +RGDINV + GDP TAKSQFLK++E+ S RA++T+G+ +SA GLTA V R S
Sbjct: 507 PGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVS 566
Query: 440 HEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSI 499
E+ +EAGAL+LAD GVC IDEFDKM+ +D+ +IHEAMEQQ+ISI+KAG+ +L AR ++
Sbjct: 567 REWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTV 626
Query: 500 LAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLH--- 556
+AAANPI G YD S + +N++L+ PI+SRFD+ ++ D + V D +AR +V H
Sbjct: 627 IAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRH 686
Query: 557 -------------SRIEESIDRVYSLDD-----IRRYLLFARQ-FKPKISKESEDFIVEQ 597
S E ++ Y ++ +++Y+++A++ PK+++ +D + +
Sbjct: 687 HPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKM 746
Query: 598 YKHLRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSII 657
Y LR+ + S ITVR +ESMIR++EA AR+H D V V A R++ +S I
Sbjct: 747 YSDLRK---ESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFI 803
>gi|33469968 minichromosome maintenance complex component 7 isoform
1 [Homo sapiens]
Length = 719
Score = 319 bits (818), Expect = 6e-87
Identities = 216/677 (31%), Positives = 339/677 (50%), Gaps = 92/677 (13%)
Query: 24 EKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEF 83
EK +K +F ++ + + KY L E+ L V D+ + + +L +I E
Sbjct: 11 EKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVAEDDPELVDSICENA 70
Query: 84 YRVYPYLCRALKTFVKDRKE-------------------------------------IPL 106
R A++ + KE L
Sbjct: 71 RRYAKLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGMVRSPQNQYPAEL 130
Query: 107 AKDFYVAFQDLPTRHK---IRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQT 163
+ F + FQ P+ +K IRE+ + +G L + G V R V P++V T+ C C
Sbjct: 131 MRRFELYFQG-PSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGA 189
Query: 164 VIRDVEQQFKYTQPNICRNPVCANRR---RFLLDTNKSRFVDFQKVRIQETQAELPRGSI 220
Q + +C + C R R L T SRF+ FQ++++QE ++P G+I
Sbjct: 190 ETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNI 249
Query: 221 PRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYETEG 280
PRS+ V++ E AQ GD TG + + T R +
Sbjct: 250 PRSITVLVEGENTRIAQPGDHVSVTGIFLPI------------LRTGFR---------QV 288
Query: 281 IRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEM 340
++GL + + ++R+V + ++ + ES ++T +E ++ E
Sbjct: 289 VQGLLSETYLE-AHRIVKM-----------------NKSEDDESGAGELTREELRQIAE- 329
Query: 341 SQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPST 400
++ Y L S+ P I+G+++VK+ +LL+L GGV ++ G +RG+IN+C++GDP
Sbjct: 330 ---EDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSP-RGMKIRGNINICLMGDPGV 385
Query: 401 AKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCID 460
AKSQ L +++ +PR+ YT+G+ SS GLTAAV+RD S E +E GAL+LAD GVCCID
Sbjct: 386 AKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCID 445
Query: 461 EFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPISGHYDRSKSLKQNI 520
EFDKM D+ AIHE MEQQTISI KAG+ TLNAR SILAAANP G Y+ +SL+QNI
Sbjct: 446 EFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNI 505
Query: 521 NLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHSRIEESIDRVYSLDD--IRRYLLF 578
L A ++SRFDL +++ D + D +A+ I +H + + LD +RRY+
Sbjct: 506 QLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAM 565
Query: 579 ARQFKPKISKESEDFIVEQYKHLRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCD 638
R+ +P + + D+I Y +R+ + +K + + R L +++RLS A+AR+ D
Sbjct: 566 CREKQPMVPESLADYITAAYVEMRRE--AWASKDATYTSARTLLAILRLSTALARLRMVD 623
Query: 639 EVQPKHVKEAFRLLNKS 655
V+ + V EA RL+ S
Sbjct: 624 VVEKEDVNEAIRLMEMS 640
>gi|33469919 minichromosome maintenance complex component 4 [Homo
sapiens]
Length = 863
Score = 305 bits (782), Expect = 9e-83
Identities = 192/549 (34%), Positives = 302/549 (55%), Gaps = 48/549 (8%)
Query: 114 FQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFK 173
F L T++ +R L I L ISG V+RT + PE+ F C C R + +
Sbjct: 263 FNALKTKN-MRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGR 321
Query: 174 YTQPNICRNPVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAV 233
+P++C C L N+S F D Q +++QE+ ++P G P ++ + + V
Sbjct: 322 IAEPSVCGR--CHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLV 379
Query: 234 ESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDG-YETEGIRGLRALGVRDL 292
+ Q GD+ + TG VP N RVS V Y+T + +
Sbjct: 380 DKVQPGDRVNVTGIYRAVP-----------IRVNPRVSNVKSVYKTH---------IDVI 419
Query: 293 SYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCT 352
YR + K L ++ AE + + K E + E+S+ ++Y L +
Sbjct: 420 HYR-------------KTDAKRLHGLDEEAE--QKLFSEKRVELLKELSRKPDIYERLAS 464
Query: 353 SLFPTIHGNDEVKRGVLLMLFGGVPKT---TGEGTSLRGDINVCIVGDPSTAKSQFLKHV 409
+L P+I+ ++++K+G+LL LFGG K TG G R +IN+ + GDP T+KSQ L++V
Sbjct: 465 ALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRG-KFRAEINILLCGDPGTSKSQLLQYV 523
Query: 410 EEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRD 469
PR YTSGK SSA GLTA V++D E+ + V++ GAL+L+DNG+CCIDEFDKM+
Sbjct: 524 YNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNEST 583
Query: 470 QVAIHEAMEQQTISITKAGVKATLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSR 529
+ +HE MEQQT+SI KAG+ LNARTS+LAAANPI ++ K+ +NI L ++SR
Sbjct: 584 RSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSR 643
Query: 530 FDLFFILVDECNEVTDYAIARRIVDLHSRIEESI-DRVYSLDDIRRYLLFARQ-FKPKIS 587
FDL F+L+D +E D +A +V L+ + EE + + + ++ Y+ +A P++S
Sbjct: 644 FDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEEELLDMAVLKDYIAYAHSTIMPRLS 703
Query: 588 KESEDFIVEQYKHLRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKE 647
+E+ ++E Y +R+ S S++ RQLES+IRL+EA A++ ++V+ V+E
Sbjct: 704 EEASQALIEAYVDMRKIGSSRGMVSAY---PRQLESLIRLAEAHAKVRLSNKVEAIDVEE 760
Query: 648 AFRLLNKSI 656
A RL +++
Sbjct: 761 AKRLHREAL 769
>gi|33469917 minichromosome maintenance complex component 4 [Homo
sapiens]
Length = 863
Score = 305 bits (782), Expect = 9e-83
Identities = 192/549 (34%), Positives = 302/549 (55%), Gaps = 48/549 (8%)
Query: 114 FQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFK 173
F L T++ +R L I L ISG V+RT + PE+ F C C R + +
Sbjct: 263 FNALKTKN-MRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGR 321
Query: 174 YTQPNICRNPVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAV 233
+P++C C L N+S F D Q +++QE+ ++P G P ++ + + V
Sbjct: 322 IAEPSVCGR--CHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLV 379
Query: 234 ESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDG-YETEGIRGLRALGVRDL 292
+ Q GD+ + TG VP N RVS V Y+T + +
Sbjct: 380 DKVQPGDRVNVTGIYRAVP-----------IRVNPRVSNVKSVYKTH---------IDVI 419
Query: 293 SYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCT 352
YR + K L ++ AE + + K E + E+S+ ++Y L +
Sbjct: 420 HYR-------------KTDAKRLHGLDEEAE--QKLFSEKRVELLKELSRKPDIYERLAS 464
Query: 353 SLFPTIHGNDEVKRGVLLMLFGGVPKT---TGEGTSLRGDINVCIVGDPSTAKSQFLKHV 409
+L P+I+ ++++K+G+LL LFGG K TG G R +IN+ + GDP T+KSQ L++V
Sbjct: 465 ALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRG-KFRAEINILLCGDPGTSKSQLLQYV 523
Query: 410 EEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRD 469
PR YTSGK SSA GLTA V++D E+ + V++ GAL+L+DNG+CCIDEFDKM+
Sbjct: 524 YNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNEST 583
Query: 470 QVAIHEAMEQQTISITKAGVKATLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSR 529
+ +HE MEQQT+SI KAG+ LNARTS+LAAANPI ++ K+ +NI L ++SR
Sbjct: 584 RSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSR 643
Query: 530 FDLFFILVDECNEVTDYAIARRIVDLHSRIEESI-DRVYSLDDIRRYLLFARQ-FKPKIS 587
FDL F+L+D +E D +A +V L+ + EE + + + ++ Y+ +A P++S
Sbjct: 644 FDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEEELLDMAVLKDYIAYAHSTIMPRLS 703
Query: 588 KESEDFIVEQYKHLRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKE 647
+E+ ++E Y +R+ S S++ RQLES+IRL+EA A++ ++V+ V+E
Sbjct: 704 EEASQALIEAYVDMRKIGSSRGMVSAY---PRQLESLIRLAEAHAKVRLSNKVEAIDVEE 760
Query: 648 AFRLLNKSI 656
A RL +++
Sbjct: 761 AKRLHREAL 769
>gi|33469922 minichromosome maintenance complex component 7 isoform
2 [Homo sapiens]
Length = 543
Score = 299 bits (765), Expect = 8e-81
Identities = 182/510 (35%), Positives = 281/510 (55%), Gaps = 51/510 (10%)
Query: 151 LVSGTFLCLDCQTVIRDVEQQFKYTQPNICRNPVCANRR---RFLLDTNKSRFVDFQKVR 207
+V T+ C C Q + +C + C R R L T SRF+ FQ+++
Sbjct: 1 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMK 60
Query: 208 IQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETN 267
+QE ++P G+IPRS+ V++ E AQ GD TG + + T
Sbjct: 61 MQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPI------------LRTG 108
Query: 268 SRVSGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKN 327
R + ++GL + + ++R+V + ++ + ES
Sbjct: 109 FR---------QVVQGLLSETYLE-AHRIVKM-----------------NKSEDDESGAG 141
Query: 328 QMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLR 387
++T +E ++ E ++ Y L S+ P I+G+++VK+ +LL+L GGV ++ G +R
Sbjct: 142 ELTREELRQIAE----EDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSP-RGMKIR 196
Query: 388 GDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAG 447
G+IN+C++GDP AKSQ L +++ +PR+ YT+G+ SS GLTAAV+RD S E +E G
Sbjct: 197 GNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGG 256
Query: 448 ALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPIS 507
AL+LAD GVCCIDEFDKM D+ AIHE MEQQTISI KAG+ TLNAR SILAAANP
Sbjct: 257 ALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAY 316
Query: 508 GHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHSRIEESIDRVY 567
G Y+ +SL+QNI L A ++SRFDL +++ D + D +A+ I +H + +
Sbjct: 317 GRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFE 376
Query: 568 SLDD--IRRYLLFARQFKPKISKESEDFIVEQYKHLRQRDGSGVTKSSWRITVRQLESMI 625
LD +RRY+ R+ +P + + D+I Y +R+ + +K + + R L +++
Sbjct: 377 PLDMKLMRRYIAMCREKQPMVPESLADYITAAYVEMRRE--AWASKDATYTSARTLLAIL 434
Query: 626 RLSEAMARMHCCDEVQPKHVKEAFRLLNKS 655
RLS A+AR+ D V+ + V EA RL+ S
Sbjct: 435 RLSTALARLRMVDVVEKEDVNEAIRLMEMS 464
>gi|6631095 minichromosome maintenance complex component 3 [Homo
sapiens]
Length = 808
Score = 297 bits (761), Expect = 2e-80
Identities = 219/724 (30%), Positives = 353/724 (48%), Gaps = 112/724 (15%)
Query: 20 DEVAEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTI 79
D + Q+ +LDFL++ + + Y ELI + L+V+ DL + N++ + +
Sbjct: 9 DVELREAQRDYLDFLDD---EEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRL 65
Query: 80 QEEFYRVYPYLCRALKTFVK--DRKEIPLAKDFYVAFQ-DLPTRH-KIRELTSSRIGLLT 135
+ RALK FV D ++FYV + ++H R LTS + +
Sbjct: 66 LNNAFEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVV 125
Query: 136 RISGQVVRTHPVHPELVSGTFLCLDCQTVI--RDVEQQFKYTQPNICRNPVCANRRRFL- 192
+ G V + V P++V C + I R + P+ P L
Sbjct: 126 CVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLE 185
Query: 193 LDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVVP 252
+ S + D Q + IQE + P G +PRS++VIL + V+ A+ GD+ GT +P
Sbjct: 186 TEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLP 245
Query: 253 DVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFGG 312
G G T G ++R V +AC V
Sbjct: 246 -------------------GKKGGYTSG------------TFRTVLIACNV--------- 265
Query: 313 KELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLML 372
K++ + Q + S ++ +K++ K ++ K+++ L SL P+IHG+D VK+ +L +L
Sbjct: 266 KQMSKDAQPSFSAEDIAKIKKFSK----TRSKDIFDQLAKSLAPSIHGHDYVKKAILCLL 321
Query: 373 FGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAA 432
GGV + G+ +RGDIN+ ++GDPS AKSQ L++V +PRA+ T+G+ SS GLTAA
Sbjct: 322 LGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAA 381
Query: 433 VVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKAT 492
V D+E+ E +EAGA++LAD GV CIDEFDKM D+ AIHE MEQ ++I KAG+ A
Sbjct: 382 VTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHAR 441
Query: 493 LNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRI 552
LNAR S+LAAANP+ G YD+ K+ +NI L ++SRFDL FI++D+ + D I+ +
Sbjct: 442 LNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHV 501
Query: 553 VDLH-----------------------------SRIEESIDRVYSLDD------------ 571
+ +H S+ ++ ++Y D
Sbjct: 502 LRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEK 561
Query: 572 ------IRRYLLFARQFKPKISKESEDFIVEQYKHLRQRDG-SGVTKSSWRITVRQLESM 624
+++Y+ A+ KP +++ES +I E+Y LR +D S T + +T R LE++
Sbjct: 562 MVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETL 621
Query: 625 IRLSEAMARMHCCDEVQPKHVKEAFRLLN----KSIIRVE------TPDVNLDQEEEIQM 674
IRL+ A A+ V + +EA L+ K ++ E + D + ++EE +
Sbjct: 622 IRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKS 681
Query: 675 EVDE 678
+ D+
Sbjct: 682 QEDQ 685
>gi|23510448 minichromosome maintenance complex component 5 [Homo
sapiens]
Length = 734
Score = 291 bits (744), Expect = 2e-78
Identities = 201/657 (30%), Positives = 333/657 (50%), Gaps = 65/657 (9%)
Query: 27 QKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNT----LVVSFVDLEQFNQQLSTTIQEE 82
Q+ F +FL +++ + + ++ N + V DL F++ L+ + ++
Sbjct: 32 QRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEDLADYLYKQ 91
Query: 83 FYRVYPYLCRALKTFVKDRKEIP------LAKDFYVAFQDLPTRHKIRELTSSRIGLLTR 136
L A K V D P + +D V + + IR L S + L +
Sbjct: 92 PAEHLQLLEEAAKE-VADEVTRPRPSGEEVLQDIQVMLKSDASPSSIRSLKSDMMSHLVK 150
Query: 137 ISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQ---FKYTQPNICRN-----PVCANR 188
I G ++ V + + C C+ + ++ + Y P C P C
Sbjct: 151 IPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYALPRKCNTDQAGRPKCPLD 210
Query: 189 RRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTL 248
F++ +K + VDFQ +++QE +P G +PR +++ + G++ T+
Sbjct: 211 PYFIMP-DKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRV----TI 265
Query: 249 IVVPDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNP 308
+ + + K +R G + G+ G+R+ +R L ++
Sbjct: 266 MGIYSIKKFGLTTSR-----------GRDRVGV-GIRSSYIRVLGIQV------------ 301
Query: 309 RFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGV 368
D + + S ++ +E E+ ++ N+Y + S+ P+I G ++K+ +
Sbjct: 302 --------DTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAI 353
Query: 369 LLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAG 428
+LFGG K +G + RGDIN+ ++GDP TAKSQ LK VE+ SP VYTSGK SSAAG
Sbjct: 354 ACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAG 413
Query: 429 LTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAG 488
LTA+V+RD S F++E GA++LAD GV CIDEFDKM D+VAIHEAMEQQTISI KAG
Sbjct: 414 LTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAG 473
Query: 489 VKATLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAI 548
+ TLN+R S+LAAAN + G +D +K + NI+ I+SRFD+ FI+ DE NE D +
Sbjct: 474 ITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVML 532
Query: 549 ARRIVDLHSRI---EESIDRVYSLDDIRRYLLFAR-QFKPKISKESEDFIVEQY----KH 600
A+ ++ LH ++++ L +++++ + R + P++S E+ + + +Y
Sbjct: 533 AKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSG 592
Query: 601 LRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSII 657
RQ + +SS ITVRQLE+++R++EA+++M V+EA RL S +
Sbjct: 593 ARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTL 649
>gi|19923727 minichromosome maintenance complex component 8 isoform
1 [Homo sapiens]
Length = 840
Score = 256 bits (653), Expect = 8e-68
Identities = 182/624 (29%), Positives = 309/624 (49%), Gaps = 85/624 (13%)
Query: 122 KIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNICR 181
+++ + ++ G + G VVR + P FLC C + KY+ P C
Sbjct: 206 QLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCP 265
Query: 182 NPVCANRRRFLLDTNKSRF-VDFQKVRIQETQAELPR--GSIPRSLEVILRAEAVESAQA 238
PVC R L ++ +D+Q ++IQE ++ R G IPR++E L + V+S
Sbjct: 266 VPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVDSCVP 325
Query: 239 GDKCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVF 298
GD TG + V + AE SR + + + +F
Sbjct: 326 GDTVTITGIVKV-----------SNAEEGSR---------------------NKNDKCMF 353
Query: 299 LACCVAPTNPRFGGKELRDEEQTAE-SIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPT 357
L A + G++ + E + + + ++K+ + E+ ++NL+ + SL P
Sbjct: 354 LLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPV 413
Query: 358 IHGNDEVKRGVLLMLFGGVPKTTGEGTSL--RGDINVCIVGDPSTAKSQFLKHVEEFSPR 415
I G++ VK G+ L LFGG K + + RGD ++ +VGDP KSQ L+ +PR
Sbjct: 414 IFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPR 473
Query: 416 AVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHE 475
VY G ++ +GLT + +D S +F +EAGAL+L D G+C IDEFDKM + Q A+ E
Sbjct: 474 GVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLE 532
Query: 476 AMEQQTISITKAGVKATLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFI 535
AMEQQ+IS+ KAGV +L ARTSI+AAANP+ GHY+++K++ +N+ + + ++SRFDL FI
Sbjct: 533 AMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFI 592
Query: 536 LVDECNEVTDYAIARRIVDLHSRIEESID-----RVYSLDD------------------- 571
L+D NE D+ ++ ++ + + + +I R+ S D
Sbjct: 593 LLDTPNEHHDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKV 652
Query: 572 -------------IRRYLLFARQF-KPKISKESEDFIVEQYKHLRQRDGSGVTKSSWRIT 617
+R+Y+ +ARQ+ P++S E+ + + Y LR++ +S IT
Sbjct: 653 VPGETIDPIPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQ---SQRLNSSPIT 709
Query: 618 VRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEEEIQMEVD 677
RQLES+IRL+EA AR+ +E + ++ ++ S++ + D+ + E
Sbjct: 710 TRQLESLIRLTEARARLELREEATKEDAEDIVEIMKYSMLGTYS-----DEFGNLDFERS 764
Query: 678 EGAGGINGHADSPAPVNGINGYNE 701
+ G++ + + ++ +N E
Sbjct: 765 QHGSGMSNRSTAKRFISALNNVAE 788
>gi|33469924 minichromosome maintenance complex component 8 isoform
2 [Homo sapiens]
Length = 824
Score = 253 bits (647), Expect = 4e-67
Identities = 179/623 (28%), Positives = 302/623 (48%), Gaps = 99/623 (15%)
Query: 122 KIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNICR 181
+++ + ++ G + G VVR + P FLC C + KY+ P C
Sbjct: 206 QLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCP 265
Query: 182 NPVCANRRRFLLDTNKSRF-VDFQKVRIQETQAELPR--GSIPRSLEVILRAEAVESAQA 238
PVC R L ++ +D+Q ++IQE ++ R G IPR++E L + V+S
Sbjct: 266 VPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVDSCVP 325
Query: 239 GDKCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVF 298
GD TG + V + AE + +S G +T+
Sbjct: 326 GDTVTITGIVKV-----------SNAEEANSISNSKGQKTKS------------------ 356
Query: 299 LACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTI 358
E+ + + ++K+ + E+ ++NL+ + SL P I
Sbjct: 357 ------------------SEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVI 398
Query: 359 HGNDEVKRGVLLMLFGGVPKTTGEGTSL--RGDINVCIVGDPSTAKSQFLKHVEEFSPRA 416
G++ VK G+ L LFGG K + + RGD ++ +VGDP KSQ L+ +PR
Sbjct: 399 FGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRG 458
Query: 417 VYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEA 476
VY G ++ +GLT + +D S +F +EAGAL+L D G+C IDEFDKM + Q A+ EA
Sbjct: 459 VYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEA 517
Query: 477 MEQQTISITKAGVKATLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFIL 536
MEQQ+IS+ KAGV +L ARTSI+AAANP+ GHY+++K++ +N+ + + ++SRFDL FIL
Sbjct: 518 MEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFIL 577
Query: 537 VDECNEVTDYAIARRIVDLHSRIEESID-----RVYSLDD-------------------- 571
+D NE D+ ++ ++ + + + +I R+ S D
Sbjct: 578 LDTPNEHHDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVV 637
Query: 572 ------------IRRYLLFARQF-KPKISKESEDFIVEQYKHLRQRDGSGVTKSSWRITV 618
+R+Y+ +ARQ+ P++S E+ + + Y LR++ +S IT
Sbjct: 638 PGETIDPIPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQ---SQRLNSSPITT 694
Query: 619 RQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEEEIQMEVDE 678
RQLES+IRL+EA AR+ +E + ++ ++ S++ + D+ + E +
Sbjct: 695 RQLESLIRLTEARARLELREEATKEDAEDIVEIMKYSMLGTYS-----DEFGNLDFERSQ 749
Query: 679 GAGGINGHADSPAPVNGINGYNE 701
G++ + + ++ +N E
Sbjct: 750 HGSGMSNRSTAKRFISALNNVAE 772
>gi|23397546 minichromosome maintenance complex component 9 [Homo
sapiens]
Length = 391
Score = 109 bits (273), Expect = 9e-24
Identities = 105/426 (24%), Positives = 190/426 (44%), Gaps = 75/426 (17%)
Query: 28 KLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEFYRVY 87
++F ++ E+ +D L + +E +VV+ + L + N ++ E++ ++
Sbjct: 11 QVFESYVSEYHKND----ILLILKERDEDAHYPVVVNAMTLFETNMEIG-----EYFNMF 61
Query: 88 PY---------LCRALKTFVKDRKE---IPLAKDFYVAFQDLPTRHK-IRELT--SSRIG 132
P L R+ T ++ + + + ++ + LP + +RE + +G
Sbjct: 62 PSEVLTIFDSALRRSALTILQSLSQPEAVSMKQNLHARISGLPVCPELVREHIPKTKDVG 121
Query: 133 LLTRISGQVVRTHPVHPELVSGTFLCLDCQTVI---RDVEQQFKYTQPNICRNPVCANRR 189
++G V+RT V ++C C+ V D EQ + + +P+ C + +
Sbjct: 122 HFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFVIKADFEQYYTFCRPSSCPSLESCDSS 181
Query: 190 RFL----LDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFT 245
+F L ++ +R D+Q+++IQE L GSIPRS++VIL + V+S ++GD
Sbjct: 182 KFTCLSGLSSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIY 241
Query: 246 GTLIVVPDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAP 305
G +V K R E +V A +
Sbjct: 242 G---IVMQRWKPFQQDVRCEVE----------------------------IVLKANYIQV 270
Query: 306 TNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEM-SQDKNLYHN-LCTSLFPTIHGNDE 363
N EQ++ I ++ KE+E +E D N + SL P + G
Sbjct: 271 NN-----------EQSSGIIMDEEVQKEFEDFWEYYKSDPFAGRNVILASLCPQVFGMYL 319
Query: 364 VKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKA 423
VK V ++L GG+ +T GT +RG+ ++ +VGDP T KSQFLK+ + +PR+V T+G
Sbjct: 320 VKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIG 379
Query: 424 SSAAGL 429
S++AG+
Sbjct: 380 STSAGI 385
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 37.0 bits (84), Expect = 0.074
Identities = 28/102 (27%), Positives = 53/102 (51%), Gaps = 6/102 (5%)
Query: 668 QEEEIQMEVDEGAGGINGHADSPAPVNGINGYNEDINQESAPKASLRLGFSEYCRISNLI 727
+ +E++ ++D+ N V N Y E++ QE+ KA + G +E ++ N+
Sbjct: 586 KRDEVKCKLDKSEENCNNLRKQ---VENKNKYIEELQQEN--KALKKKGTAESKQL-NVY 639
Query: 728 VLHLRKVEEEEDESALKRSELVNWYLKEIESEIDSEEELINK 769
+ + K+E E + + K E+ + Y KEIE + SEE L+ +
Sbjct: 640 EIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEE 681
>gi|50659082 suppressor of variegation 4-20 homolog 1 isoform 1
[Homo sapiens]
Length = 885
Score = 35.4 bits (80), Expect = 0.22
Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 4/64 (6%)
Query: 418 YTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAM 477
+ SG SS+ L + RDEE+ E L +NGVCC D ++ R +V +
Sbjct: 766 FNSGSGSSSTKLKIQLKRDEENRGSYTEG----LHENGVCCSDPLSLLESRMEVDDYSQY 821
Query: 478 EQQT 481
E+++
Sbjct: 822 EEES 825
>gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1
[Homo sapiens]
Length = 871
Score = 34.3 bits (77), Expect = 0.48
Identities = 46/244 (18%), Positives = 93/244 (38%), Gaps = 30/244 (12%)
Query: 605 DGSGVTKSSWRITVRQLESMIRLS------------------------EAMARMHCCDEV 640
+GS + VRQL+ + RL EA+AR
Sbjct: 171 EGSQALSQQAEVIVRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELEALARAEKAGRA 230
Query: 641 QPKHVKEAFRLLNKSIIRVETPDVNLDQEEEIQMEVDEGAGGI-NGHADSPAPVNG-ING 698
+ + ++ A L ++R + + + EE+Q E + H ++ + + G
Sbjct: 231 EAEGLRAA--LAGAEVVRKNLEEGSQRELEEVQRLHQEQLSSLTQAHEEALSSLTSKAEG 288
Query: 699 YNEDINQESAPKASLRLGFSEYCRISNLIVLHLRKVEEEEDESALKRSELVNWYLKEIES 758
+ ++ +A +E R + L+ L K +E+ + L + +++ S
Sbjct: 289 LEKSLSSLETRRAGEAKELAEAQREAELLRKQLSKTQEDLEAQVTLVENLRKYVGEQVPS 348
Query: 759 EIDSEEELINKKRIIEKVIHRLTHYD--HVLIELTQAGLKGSTEGSESYEEDPYLVVNPN 816
E+ S+ + +++++E + H D H EL Q ++ T EE+ V P+
Sbjct: 349 EVHSQTWELERQKLLETMQHLQEDRDSLHATAELLQVRVQSLTHILALQEEELTRKVQPS 408
Query: 817 YLLE 820
LE
Sbjct: 409 DSLE 412
>gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2
[Homo sapiens]
Length = 835
Score = 34.3 bits (77), Expect = 0.48
Identities = 46/244 (18%), Positives = 93/244 (38%), Gaps = 30/244 (12%)
Query: 605 DGSGVTKSSWRITVRQLESMIRLS------------------------EAMARMHCCDEV 640
+GS + VRQL+ + RL EA+AR
Sbjct: 135 EGSQALSQQAEVIVRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELEALARAEKAGRA 194
Query: 641 QPKHVKEAFRLLNKSIIRVETPDVNLDQEEEIQMEVDEGAGGI-NGHADSPAPVNG-ING 698
+ + ++ A L ++R + + + EE+Q E + H ++ + + G
Sbjct: 195 EAEGLRAA--LAGAEVVRKNLEEGSQRELEEVQRLHQEQLSSLTQAHEEALSSLTSKAEG 252
Query: 699 YNEDINQESAPKASLRLGFSEYCRISNLIVLHLRKVEEEEDESALKRSELVNWYLKEIES 758
+ ++ +A +E R + L+ L K +E+ + L + +++ S
Sbjct: 253 LEKSLSSLETRRAGEAKELAEAQREAELLRKQLSKTQEDLEAQVTLVENLRKYVGEQVPS 312
Query: 759 EIDSEEELINKKRIIEKVIHRLTHYD--HVLIELTQAGLKGSTEGSESYEEDPYLVVNPN 816
E+ S+ + +++++E + H D H EL Q ++ T EE+ V P+
Sbjct: 313 EVHSQTWELERQKLLETMQHLQEDRDSLHATAELLQVRVQSLTHILALQEEELTRKVQPS 372
Query: 817 YLLE 820
LE
Sbjct: 373 DSLE 376
>gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3
[Homo sapiens]
Length = 782
Score = 34.3 bits (77), Expect = 0.48
Identities = 46/244 (18%), Positives = 93/244 (38%), Gaps = 30/244 (12%)
Query: 605 DGSGVTKSSWRITVRQLESMIRLS------------------------EAMARMHCCDEV 640
+GS + VRQL+ + RL EA+AR
Sbjct: 82 EGSQALSQQAEVIVRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELEALARAEKAGRA 141
Query: 641 QPKHVKEAFRLLNKSIIRVETPDVNLDQEEEIQMEVDEGAGGI-NGHADSPAPVNG-ING 698
+ + ++ A L ++R + + + EE+Q E + H ++ + + G
Sbjct: 142 EAEGLRAA--LAGAEVVRKNLEEGSQRELEEVQRLHQEQLSSLTQAHEEALSSLTSKAEG 199
Query: 699 YNEDINQESAPKASLRLGFSEYCRISNLIVLHLRKVEEEEDESALKRSELVNWYLKEIES 758
+ ++ +A +E R + L+ L K +E+ + L + +++ S
Sbjct: 200 LEKSLSSLETRRAGEAKELAEAQREAELLRKQLSKTQEDLEAQVTLVENLRKYVGEQVPS 259
Query: 759 EIDSEEELINKKRIIEKVIHRLTHYD--HVLIELTQAGLKGSTEGSESYEEDPYLVVNPN 816
E+ S+ + +++++E + H D H EL Q ++ T EE+ V P+
Sbjct: 260 EVHSQTWELERQKLLETMQHLQEDRDSLHATAELLQVRVQSLTHILALQEEELTRKVQPS 319
Query: 817 YLLE 820
LE
Sbjct: 320 DSLE 323
>gi|56788364 tubulin, gamma complex associated protein 6 [Homo
sapiens]
Length = 1819
Score = 34.3 bits (77), Expect = 0.48
Identities = 34/147 (23%), Positives = 60/147 (40%), Gaps = 16/147 (10%)
Query: 550 RRIVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKHLRQRDGSGV 609
RR +++ L D R L + + ++ +++ +V+ Y L
Sbjct: 719 RRQAARQEELDDDFSYARELRDRERRL---KSLEEELERKARQALVDHYSKLSAEAARRE 775
Query: 610 TKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQE 669
K+ WRI +LES A R DE KH++E + ++++ E PDV L
Sbjct: 776 QKALWRIQRHRLES------ARLRFLLEDE---KHIQEMLKAVSEAHQPQEPPDVLLSVH 826
Query: 670 EEIQMEVDE----GAGGINGHADSPAP 692
++ E G G +G A+ +P
Sbjct: 827 PQVTSPGPEHPEGGQGCDSGSAEQHSP 853
>gi|33946313 ninein isoform 4 [Homo sapiens]
Length = 2096
Score = 33.9 bits (76), Expect = 0.63
Identities = 20/78 (25%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
Query: 725 NLIVLHLRKVEEEEDESALKRSELVNWYLKEIESEIDSEEELINKKRIIEKVIHRLTHYD 784
N++VL L+ E+ ES ++R + W EI+ + ++ + +E+ + R+
Sbjct: 1328 NVLVLRLQGKIEKLQESVVQRCDCCLWEASLENLEIEPDGNILQLNQTLEECVPRVRSVH 1387
Query: 785 HVLIELTQAG--LKGSTE 800
HV+ E Q L+G+T+
Sbjct: 1388 HVIEECKQENQYLEGNTQ 1405
>gi|33946321 ninein isoform 5 [Homo sapiens]
Length = 2090
Score = 33.9 bits (76), Expect = 0.63
Identities = 20/78 (25%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
Query: 725 NLIVLHLRKVEEEEDESALKRSELVNWYLKEIESEIDSEEELINKKRIIEKVIHRLTHYD 784
N++VL L+ E+ ES ++R + W EI+ + ++ + +E+ + R+
Sbjct: 1322 NVLVLRLQGKIEKLQESVVQRCDCCLWEASLENLEIEPDGNILQLNQTLEECVPRVRSVH 1381
Query: 785 HVLIELTQAG--LKGSTE 800
HV+ E Q L+G+T+
Sbjct: 1382 HVIEECKQENQYLEGNTQ 1399
>gi|148536871 ninein isoform 1 [Homo sapiens]
Length = 2046
Score = 33.9 bits (76), Expect = 0.63
Identities = 20/78 (25%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
Query: 725 NLIVLHLRKVEEEEDESALKRSELVNWYLKEIESEIDSEEELINKKRIIEKVIHRLTHYD 784
N++VL L+ E+ ES ++R + W EI+ + ++ + +E+ + R+
Sbjct: 1322 NVLVLRLQGKIEKLQESVVQRCDCCLWEASLENLEIEPDGNILQLNQTLEECVPRVRSVH 1381
Query: 785 HVLIELTQAG--LKGSTE 800
HV+ E Q L+G+T+
Sbjct: 1382 HVIEECKQENQYLEGNTQ 1399
>gi|148536869 ninein isoform 2 [Homo sapiens]
Length = 2133
Score = 33.9 bits (76), Expect = 0.63
Identities = 20/78 (25%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
Query: 725 NLIVLHLRKVEEEEDESALKRSELVNWYLKEIESEIDSEEELINKKRIIEKVIHRLTHYD 784
N++VL L+ E+ ES ++R + W EI+ + ++ + +E+ + R+
Sbjct: 1322 NVLVLRLQGKIEKLQESVVQRCDCCLWEASLENLEIEPDGNILQLNQTLEECVPRVRSVH 1381
Query: 785 HVLIELTQAG--LKGSTE 800
HV+ E Q L+G+T+
Sbjct: 1382 HVIEECKQENQYLEGNTQ 1399
>gi|239752405 PREDICTED: similar to cancer/testis antigen family
147, member B1 [Homo sapiens]
Length = 290
Score = 33.5 bits (75), Expect = 0.82
Identities = 42/163 (25%), Positives = 69/163 (42%), Gaps = 16/163 (9%)
Query: 661 TPDVNLDQEEEIQMEVDEGA---------GGINGHADSPAPVNGINGYNEDINQESAPKA 711
T D +L QE++ EGA GG +G DS V G+ G + +E +A
Sbjct: 4 TGDQDLIQEDQEAPVNQEGAQAEAGGDREGGDSG-PDSGNTVAGVAGPMRGLGEEEGEQA 62
Query: 712 SLRLGFSEYCRISNLIV-LHLRKVEEEEDESALKRSELVNWYLKEIESEIDSEEELINKK 770
+ G + N +R VEEEE+E +R+E N+ L +
Sbjct: 63 A---GLAAAPGGGNAEEDSEIRIVEEEEEEE--ERNEADNFDLVAAARRYPIRGFRMEFL 117
Query: 771 RIIEKVIHRLTHYDHVLIELTQAGLKGSTEGSESYEEDPYLVV 813
++ ++ R+ H DH+LI + L + S E+P L++
Sbjct: 118 DMVHSLLLRIYHNDHILIRMRGGRLMRGXTAAPSGSEEPRLLL 160
>gi|209954823 minichromosome maintenance complex component-like
isoform b [Homo sapiens]
Length = 632
Score = 33.1 bits (74), Expect = 1.1
Identities = 51/232 (21%), Positives = 94/232 (40%), Gaps = 23/232 (9%)
Query: 444 IEAGALMLADNGVCCIDEF--DKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSILA 501
I+AG+ +LA G+C I + K D +Q + +E ++I++ G K + +
Sbjct: 395 IQAGSALLAKGGICFIGDLASHKKDKLEQ--LQTVLESRSITVYIPGKKFGEDIDQQMTF 452
Query: 502 AAN-PISGHYDRSKSLKQNINLSAPIMSRFDLFFI---------LVDECNEVTDYAIARR 551
D S ++N ++ + D I L+ CNE +
Sbjct: 453 PVQCSFWSFVDVDSSSRRNAQKINTLIGQMDCSLIPANLVEAFGLLINCNESSPCHPFLP 512
Query: 552 IVD--LHSRIEE-----SIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKHLRQR 604
V L+ I + R ++ +D + L FA+ + S E+E Y R+
Sbjct: 513 TVQHTLNKAINPEGLFYAASRQFTTEDFEKLLAFAKNLNVEFSLEAERMTHGYYLASRRI 572
Query: 605 DGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSI 656
V S +++ L+ ++ LSEA AR++ ++V + V A L S+
Sbjct: 573 RTGSVCGS--KLSASALKYLVFLSEAHARLNLRNKVLKEDVLIAALLFETSL 622
>gi|209954821 minichromosome maintenance complex component-like
isoform a [Homo sapiens]
Length = 681
Score = 33.1 bits (74), Expect = 1.1
Identities = 51/232 (21%), Positives = 94/232 (40%), Gaps = 23/232 (9%)
Query: 444 IEAGALMLADNGVCCIDEF--DKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSILA 501
I+AG+ +LA G+C I + K D +Q + +E ++I++ G K + +
Sbjct: 395 IQAGSALLAKGGICFIGDLASHKKDKLEQ--LQTVLESRSITVYIPGKKFGEDIDQQMTF 452
Query: 502 AAN-PISGHYDRSKSLKQNINLSAPIMSRFDLFFI---------LVDECNEVTDYAIARR 551
D S ++N ++ + D I L+ CNE +
Sbjct: 453 PVQCSFWSFVDVDSSSRRNAQKINTLIGQMDCSLIPANLVEAFGLLINCNESSPCHPFLP 512
Query: 552 IVD--LHSRIEE-----SIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKHLRQR 604
V L+ I + R ++ +D + L FA+ + S E+E Y R+
Sbjct: 513 TVQHTLNKAINPEGLFYAASRQFTTEDFEKLLAFAKNLNVEFSLEAERMTHGYYLASRRI 572
Query: 605 DGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSI 656
V S +++ L+ ++ LSEA AR++ ++V + V A L S+
Sbjct: 573 RTGSVCGS--KLSASALKYLVFLSEAHARLNLRNKVLKEDVLIAALLFETSL 622
>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]
Length = 561
Score = 32.7 bits (73), Expect = 1.4
Identities = 23/102 (22%), Positives = 54/102 (52%), Gaps = 4/102 (3%)
Query: 691 APVNGINGYNEDINQESAPKASLRLGFSEYCRISNLIVLHLRKVEEEEDESALKRSELVN 750
+P+ GI+ Y+ ++++ PK L S++ K E + + EL++
Sbjct: 419 SPLEGISHYHINLDETQVPKKKLFQVESQFDDFMAEKEAVSSKCVNLAKEIQVFQQELLS 478
Query: 751 WYLKEIESEIDSEEELINKKRIIEKVIHRLTHYDHVLIELTQ 792
+K+++ E + EE +KK + E++++ TH ++ ++EL++
Sbjct: 479 --MKKVQQECEKLEE--DKKMLEEEILNLKTHMENSMVELSK 516
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 32.3 bits (72), Expect = 1.8
Identities = 32/118 (27%), Positives = 52/118 (44%), Gaps = 15/118 (12%)
Query: 691 APVNGINGYNEDINQESAPKASLRLGFSEYCRISNLIVLHLRKVEEEEDESALKRSELVN 750
A V+ + G NE++ QE + +S+ +NL + HL E++ S L++SE N
Sbjct: 703 AQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHL-----EKETSLLRQSEGSN 757
Query: 751 WYLKEI---ESEIDSEEELINKKRIIEKVIHRLTHYDHVLIELTQAGLKGSTEGSESY 805
K I + S +IN + E +IH L +E + LK + E Y
Sbjct: 758 VVFKGIDLPDGIAPSSASIINSQN--EYLIHLLQE-----LENKEKKLKNLEDSLEDY 808
>gi|115527120 nebulin [Homo sapiens]
Length = 6669
Score = 32.3 bits (72), Expect = 1.8
Identities = 40/180 (22%), Positives = 77/180 (42%), Gaps = 21/180 (11%)
Query: 502 AANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHSR--I 559
A +PI+ H+ + L A R D + ++VDE + +I + R
Sbjct: 5386 ADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNY 5445
Query: 560 EESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVE-QYKHLRQRDGSGVTKSSWRITV 618
E+S D+ S+ D +L K++K+ D + + +Y + R + + + + V
Sbjct: 5446 EKSKDKFTSIVDTPEHLR-----TTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHV 5500
Query: 619 RQLE---SMIRLSEAMAR--MHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEEEIQ 673
R+++ S ++ E R +C E H+K A K +V T NLD +++ +
Sbjct: 5501 RKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAA-----KDAYKVNT---NLDYKKQYE 5552
>gi|217416374 hypothetical protein LOC92749 [Homo sapiens]
Length = 740
Score = 32.3 bits (72), Expect = 1.8
Identities = 34/137 (24%), Positives = 61/137 (44%), Gaps = 19/137 (13%)
Query: 472 AIHEAMEQQTISITKAGVKATLNARTSILAAANPISG----HYDRSKSLKQNINLSAPIM 527
++H Q+ I + + A L AR A + G D+SKS KQ
Sbjct: 26 SVHSDNSQERIQARRLRIAARLEARRRE-ALGEYLDGKKESEEDQSKSYKQKEE------ 78
Query: 528 SRFDLFFILVDECNEVTDYAIARRIVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKIS 587
SR L +L+ VT+ +A I ++H R+EE ++I+R + + + K S
Sbjct: 79 SRLKLAKLLLCGTELVTNIQVAIDIREIHRRVEE--------EEIKRQRIEKLENEVKTS 130
Query: 588 KESEDFIVEQYKHLRQR 604
++ D I +++ +Q+
Sbjct: 131 QDKFDEITSKWEEGKQK 147
>gi|121949802 cancer/testis antigen family 47, member A1 [Homo
sapiens]
Length = 288
Score = 31.6 bits (70), Expect = 3.1
Identities = 34/138 (24%), Positives = 53/138 (38%), Gaps = 16/138 (11%)
Query: 667 DQEEEIQMEVDE----GAGGINGHADSP--------APVNGINGYNEDINQESAPKASLR 714
DQE + E + GAG G P A V G+ G E + +E +A+
Sbjct: 13 DQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGL 72
Query: 715 LGFSEYCRISNLIVLHLRKVEEEEDESALKRSELVNWYLKEIESEIDSEEELINKKRIIE 774
+ EEEE+E +E N+ L + + ++
Sbjct: 73 AAVPRGGSAEEDSDIGPATEEEEEEEG----NEAANFDLAVVARRYPASGIHFVLLDMVH 128
Query: 775 KVIHRLTHYDHVLIELTQ 792
++HRL+H DH+LIE Q
Sbjct: 129 SLLHRLSHNDHILIENRQ 146
>gi|121949798 cancer/testis antigen family 47, member A2 [Homo
sapiens]
Length = 288
Score = 31.6 bits (70), Expect = 3.1
Identities = 34/138 (24%), Positives = 53/138 (38%), Gaps = 16/138 (11%)
Query: 667 DQEEEIQMEVDE----GAGGINGHADSP--------APVNGINGYNEDINQESAPKASLR 714
DQE + E + GAG G P A V G+ G E + +E +A+
Sbjct: 13 DQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGL 72
Query: 715 LGFSEYCRISNLIVLHLRKVEEEEDESALKRSELVNWYLKEIESEIDSEEELINKKRIIE 774
+ EEEE+E +E N+ L + + ++
Sbjct: 73 AAVPRGGSAEEDSDIGPATEEEEEEEG----NEAANFDLAVVARRYPASGIHFVLLDMVH 128
Query: 775 KVIHRLTHYDHVLIELTQ 792
++HRL+H DH+LIE Q
Sbjct: 129 SLLHRLSHNDHILIENRQ 146
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,105,480
Number of Sequences: 37866
Number of extensions: 1271577
Number of successful extensions: 3752
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 3659
Number of HSP's gapped (non-prelim): 105
length of query: 821
length of database: 18,247,518
effective HSP length: 111
effective length of query: 710
effective length of database: 14,044,392
effective search space: 9971518320
effective search space used: 9971518320
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.