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Search of human proteins with 74096429
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|74096429 RAB41, member RAS oncogene family [Homo sapiens]
(222 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|74096429 RAB41, member RAS oncogene family [Homo sapiens] 444 e-125
gi|96975097 RAB6B, member RAS oncogene family [Homo sapiens] 260 6e-70
gi|38679888 RAB6A, member RAS oncogene family isoform b [Homo sa... 257 5e-69
gi|19923231 RAB6A, member RAS oncogene family isoform a [Homo sa... 253 7e-68
gi|116875763 RAB6C, member RAS oncogene family [Homo sapiens] 229 1e-60
gi|117938299 RAB6C-like [Homo sapiens] 227 5e-60
gi|19923262 RAB5A, member RAS oncogene family [Homo sapiens] 150 1e-36
gi|41393614 RAB5C, member RAS oncogene family isoform a [Homo sa... 147 5e-36
gi|41393545 RAB5C, member RAS oncogene family isoform b [Homo sa... 147 5e-36
gi|4506371 RAB5B, member RAS oncogene family [Homo sapiens] 147 7e-36
gi|33695095 ras-related GTP-binding protein RAB10 [Homo sapiens] 145 4e-35
gi|7706563 RAB8B, member RAS oncogene family [Homo sapiens] 137 6e-33
gi|33589861 RAB31, member RAS oncogene family [Homo sapiens] 135 2e-32
gi|16933567 mel transforming oncogene [Homo sapiens] 135 3e-32
gi|106507164 RAB12, member RAS oncogene family [Homo sapiens] 135 3e-32
gi|4506367 RAB3A, member RAS oncogene family [Homo sapiens] 134 5e-32
gi|50234889 RAB43 protein [Homo sapiens] 134 5e-32
gi|54859685 RAB37, member RAS oncogene family isoform 2 [Homo sa... 134 8e-32
gi|19923985 RAB3C, member RAS oncogene family [Homo sapiens] 133 1e-31
gi|21361418 RAB30, member RAS oncogene family [Homo sapiens] 133 1e-31
gi|4759000 RAB3D, member RAS oncogene family [Homo sapiens] 133 1e-31
gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo sa... 133 1e-31
gi|10190714 RAS-related protein RAB-22A [Homo sapiens] 130 7e-31
gi|7661922 RAB21, member RAS oncogene family [Homo sapiens] 130 1e-30
gi|4506363 RAB13, member RAS oncogene family [Homo sapiens] 129 2e-30
gi|19923750 RAB3B, member RAS oncogene family [Homo sapiens] 129 2e-30
gi|46361978 RAB26, member RAS oncogene family [Homo sapiens] 128 4e-30
gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene fa... 127 1e-29
gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens] 127 1e-29
gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens] 127 1e-29
>gi|74096429 RAB41, member RAS oncogene family [Homo sapiens]
Length = 222
Score = 444 bits (1141), Expect = e-125
Identities = 222/222 (100%), Positives = 222/222 (100%)
Query: 1 MSAFGHDEAWMEAGGFGLEAAERTEYQSLCKSKLLFLGEQSVGKTSIISRFMYNSFGCAC 60
MSAFGHDEAWMEAGGFGLEAAERTEYQSLCKSKLLFLGEQSVGKTSIISRFMYNSFGCAC
Sbjct: 1 MSAFGHDEAWMEAGGFGLEAAERTEYQSLCKSKLLFLGEQSVGKTSIISRFMYNSFGCAC 60
Query: 61 QATVGIDFLSKTMYLEDQIVQLQLWDTAGQERFHSLIPSYIRDSTIAVVVYDITNINSFK 120
QATVGIDFLSKTMYLEDQIVQLQLWDTAGQERFHSLIPSYIRDSTIAVVVYDITNINSFK
Sbjct: 61 QATVGIDFLSKTMYLEDQIVQLQLWDTAGQERFHSLIPSYIRDSTIAVVVYDITNINSFK 120
Query: 121 ETDKWVEHVRAERGDDVVIMLLGNKIDLDNKRQVTAEQGEEKSRNLNVMFIETSAKTGYN 180
ETDKWVEHVRAERGDDVVIMLLGNKIDLDNKRQVTAEQGEEKSRNLNVMFIETSAKTGYN
Sbjct: 121 ETDKWVEHVRAERGDDVVIMLLGNKIDLDNKRQVTAEQGEEKSRNLNVMFIETSAKTGYN 180
Query: 181 VKKLFRRVASALLSTRTSPPPKEGTVEIELESFEESGNRSYC 222
VKKLFRRVASALLSTRTSPPPKEGTVEIELESFEESGNRSYC
Sbjct: 181 VKKLFRRVASALLSTRTSPPPKEGTVEIELESFEESGNRSYC 222
>gi|96975097 RAB6B, member RAS oncogene family [Homo sapiens]
Length = 208
Score = 260 bits (665), Expect = 6e-70
Identities = 130/188 (69%), Positives = 159/188 (84%), Gaps = 1/188 (0%)
Query: 29 LCKSKLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTA 88
L K KL+FLGEQSVGKTS+I+RFMY+SF QAT+GIDFLSKTMYLED+ V+LQLWDTA
Sbjct: 11 LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTA 70
Query: 89 GQERFHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDL 148
GQERF SLIPSYIRDST+AVVVYDITN+NSF++T KW++ VR ERG DV+IML+GNK DL
Sbjct: 71 GQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDL 130
Query: 149 DNKRQVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALLS-TRTSPPPKEGTVE 207
+KRQ+T E+GE++++ L+VMFIETSAKTGYNVK+LFRRVASAL KEG ++
Sbjct: 131 ADKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLFRRVASALPGMENVQEKSKEGMID 190
Query: 208 IELESFEE 215
I+L+ +E
Sbjct: 191 IKLDKPQE 198
>gi|38679888 RAB6A, member RAS oncogene family isoform b [Homo
sapiens]
Length = 208
Score = 257 bits (657), Expect = 5e-69
Identities = 130/188 (69%), Positives = 157/188 (83%), Gaps = 1/188 (0%)
Query: 29 LCKSKLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTA 88
L K KL+FLGEQSVGKTS+I+RFMY+SF QAT+GIDFLSKTMYLED+ V+LQLWDTA
Sbjct: 11 LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTA 70
Query: 89 GQERFHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDL 148
GQERF SLIPSYIRDST+AVVVYDITN+NSF++T KW++ VR ERG DV+IML+GNK DL
Sbjct: 71 GQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDL 130
Query: 149 DNKRQVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALLSTR-TSPPPKEGTVE 207
+KRQV+ E+GE K++ LNVMFIETSAK GYNVK+LFRRVA+AL T +E ++
Sbjct: 131 ADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSREDMID 190
Query: 208 IELESFEE 215
I+LE +E
Sbjct: 191 IKLEKPQE 198
>gi|19923231 RAB6A, member RAS oncogene family isoform a [Homo
sapiens]
Length = 208
Score = 253 bits (647), Expect = 7e-68
Identities = 128/188 (68%), Positives = 155/188 (82%), Gaps = 1/188 (0%)
Query: 29 LCKSKLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTA 88
L K KL+FLGEQSVGKTS+I+RFMY+SF QAT+GIDFLSKTMYLED+ ++LQLWDTA
Sbjct: 11 LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTA 70
Query: 89 GQERFHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDL 148
GQERF SLIPSYIRDS AVVVYDITN+NSF++T KW++ VR ERG DV+IML+GNK DL
Sbjct: 71 GQERFRSLIPSYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDL 130
Query: 149 DNKRQVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALLSTR-TSPPPKEGTVE 207
+KRQV+ E+GE K++ LNVMFIETSAK GYNVK+LFRRVA+AL T +E ++
Sbjct: 131 ADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSREDMID 190
Query: 208 IELESFEE 215
I+LE +E
Sbjct: 191 IKLEKPQE 198
>gi|116875763 RAB6C, member RAS oncogene family [Homo sapiens]
Length = 254
Score = 229 bits (584), Expect = 1e-60
Identities = 118/188 (62%), Positives = 144/188 (76%), Gaps = 1/188 (0%)
Query: 29 LCKSKLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTA 88
L K KL+FLGEQSV KTS+I+RF Y+SF QA +GIDFLSKTMYLED + L+LWDTA
Sbjct: 11 LRKFKLVFLGEQSVAKTSLITRFRYDSFDNTYQAIIGIDFLSKTMYLEDGTIGLRLWDTA 70
Query: 89 GQERFHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDL 148
GQER SLIP YIRDS AVVVYDITN+NSF++T KW++ VR ERG DV+I L+GN+ DL
Sbjct: 71 GQERLRSLIPRYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIITLVGNRTDL 130
Query: 149 DNKRQVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALLSTR-TSPPPKEGTVE 207
+KRQV+ E+GE K++ LNV FIET AK GYNVK+LFRRVA+AL T +E +
Sbjct: 131 ADKRQVSVEEGERKAKGLNVTFIETRAKAGYNVKQLFRRVAAALPGMESTQDGSREDMSD 190
Query: 208 IELESFEE 215
I+LE +E
Sbjct: 191 IKLEKPQE 198
>gi|117938299 RAB6C-like [Homo sapiens]
Length = 254
Score = 227 bits (579), Expect = 5e-60
Identities = 118/188 (62%), Positives = 143/188 (76%), Gaps = 1/188 (0%)
Query: 29 LCKSKLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTA 88
L K KL+FLGEQSV KTS+I+RF Y+SF QA +GIDFLSKTMYLED + L+LWDTA
Sbjct: 11 LRKFKLVFLGEQSVAKTSLITRFRYDSFDNTYQAIIGIDFLSKTMYLEDGTIGLRLWDTA 70
Query: 89 GQERFHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDL 148
GQER SLIP YIRDS AVVVYDITN+NSF++T KW++ VR E G DV+I L+GNK DL
Sbjct: 71 GQERLRSLIPRYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTEGGSDVIITLVGNKTDL 130
Query: 149 DNKRQVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALLSTR-TSPPPKEGTVE 207
+KRQV+ E+GE K++ LNV FIET AK GYNVK+LFRRVA+AL T +E +
Sbjct: 131 ADKRQVSIEEGERKAKGLNVTFIETRAKAGYNVKQLFRRVAAALPGMESTQDGSREDMSD 190
Query: 208 IELESFEE 215
I+LE +E
Sbjct: 191 IKLEKPQE 198
>gi|19923262 RAB5A, member RAS oncogene family [Homo sapiens]
Length = 215
Score = 150 bits (378), Expect = 1e-36
Identities = 72/172 (41%), Positives = 111/172 (64%)
Query: 29 LCKSKLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTA 88
+C+ KL+ LGE +VGK+S++ RF+ F ++T+G FL++T+ L+D V+ ++WDTA
Sbjct: 18 ICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTA 77
Query: 89 GQERFHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDL 148
GQER+HSL P Y R + A+VVYDITN SF WV+ ++ + ++VI L GNK DL
Sbjct: 78 GQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADL 137
Query: 149 DNKRQVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALLSTRTSPP 200
NKR V ++ + + + +++F+ETSAKT NV ++F +A L P
Sbjct: 138 ANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNP 189
>gi|41393614 RAB5C, member RAS oncogene family isoform a [Homo
sapiens]
Length = 216
Score = 147 bits (372), Expect = 5e-36
Identities = 69/164 (42%), Positives = 111/164 (67%)
Query: 29 LCKSKLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTA 88
+C+ KL+ LGE +VGK+S++ RF+ F ++T+G FL++T+ L+D V+ ++WDTA
Sbjct: 19 ICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTA 78
Query: 89 GQERFHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDL 148
GQER+HSL P Y R + A+VVYDITN ++F WV+ ++ + ++VI L GNK DL
Sbjct: 79 GQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADL 138
Query: 149 DNKRQVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASAL 192
+KR V ++ + + + +++F+ETSAKT NV ++F +A L
Sbjct: 139 ASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKL 182
>gi|41393545 RAB5C, member RAS oncogene family isoform b [Homo
sapiens]
Length = 216
Score = 147 bits (372), Expect = 5e-36
Identities = 69/164 (42%), Positives = 111/164 (67%)
Query: 29 LCKSKLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTA 88
+C+ KL+ LGE +VGK+S++ RF+ F ++T+G FL++T+ L+D V+ ++WDTA
Sbjct: 19 ICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTA 78
Query: 89 GQERFHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDL 148
GQER+HSL P Y R + A+VVYDITN ++F WV+ ++ + ++VI L GNK DL
Sbjct: 79 GQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADL 138
Query: 149 DNKRQVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASAL 192
+KR V ++ + + + +++F+ETSAKT NV ++F +A L
Sbjct: 139 ASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKL 182
>gi|4506371 RAB5B, member RAS oncogene family [Homo sapiens]
Length = 215
Score = 147 bits (371), Expect = 7e-36
Identities = 71/164 (43%), Positives = 108/164 (65%)
Query: 29 LCKSKLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTA 88
+C+ KL+ LGE +VGK+S++ RF+ F ++T+G FL++++ L+D V+ ++WDTA
Sbjct: 18 ICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTA 77
Query: 89 GQERFHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDL 148
GQER+HSL P Y R + A+VVYDITN +F WV+ ++ + +VI L GNK DL
Sbjct: 78 GQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADL 137
Query: 149 DNKRQVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASAL 192
NKR V E+ + + + +++F+ETSAKT NV LF +A L
Sbjct: 138 ANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKL 181
>gi|33695095 ras-related GTP-binding protein RAB10 [Homo sapiens]
Length = 200
Score = 145 bits (365), Expect = 4e-35
Identities = 73/176 (41%), Positives = 108/176 (61%)
Query: 33 KLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQER 92
KLL +G+ VGKT ++ RF ++F +T+GIDF KT+ L+ + ++LQ+WDTAGQER
Sbjct: 11 KLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQER 70
Query: 93 FHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNKR 152
FH++ SY R + ++VYDITN SF+ KW+ ++ +DV MLLGNK D+D+KR
Sbjct: 71 FHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKR 130
Query: 153 QVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALLSTRTSPPPKEGTVEI 208
V +G + +R + F ETSAK N++K F +A +L P V+I
Sbjct: 131 VVPKGKGGQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPNSENVDI 186
>gi|7706563 RAB8B, member RAS oncogene family [Homo sapiens]
Length = 207
Score = 137 bits (346), Expect = 6e-33
Identities = 65/162 (40%), Positives = 107/162 (66%)
Query: 33 KLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQER 92
KLL +G+ VGKT ++ RF ++F +T+GIDF +T+ L+ + ++LQ+WDTAGQER
Sbjct: 10 KLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQER 69
Query: 93 FHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNKR 152
F ++ +Y R + ++VYDITN SF W+ ++ DV M+LGNK D+++KR
Sbjct: 70 FRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKR 129
Query: 153 QVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALLS 194
QV+ E+GE+ + + + F+ETSAK+ NV++ F +A +++
Sbjct: 130 QVSKERGEKLAIDYGIKFLETSAKSSANVEEAFFTLARDIMT 171
>gi|33589861 RAB31, member RAS oncogene family [Homo sapiens]
Length = 195
Score = 135 bits (341), Expect = 2e-32
Identities = 65/184 (35%), Positives = 111/184 (60%)
Query: 33 KLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQER 92
K+ LG+ VGK+SI+ RF+ + F T+G F++KT+ +++ + +WDTAGQER
Sbjct: 8 KVCLLGDTGVGKSSIVCRFVQDHFDHNISPTIGASFMTKTVPCGNELHKFLIWDTAGQER 67
Query: 93 FHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNKR 152
FHSL P Y R S AV+VYDIT +SF KWV+ ++ +++V+ + GNK DL + R
Sbjct: 68 FHSLAPMYYRGSAAAVIVYDITKQDSFYTLKKWVKELKEHGPENIVMAIAGNKCDLSDIR 127
Query: 153 QVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALLSTRTSPPPKEGTVEIELES 212
+V + +E + ++ + +ETSAK N+++LF+ ++ + GT+++E +
Sbjct: 128 EVPLKDAKEYAESIGAIVVETSAKNAINIEELFQGISRQIPPLDPHENGNNGTIKVEKPT 187
Query: 213 FEES 216
+ S
Sbjct: 188 MQAS 191
>gi|16933567 mel transforming oncogene [Homo sapiens]
Length = 207
Score = 135 bits (340), Expect = 3e-32
Identities = 65/157 (41%), Positives = 102/157 (64%)
Query: 33 KLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQER 92
KLL +G+ VGKT ++ RF ++F +T+GIDF +T+ L+ + ++LQ+WDTAGQER
Sbjct: 10 KLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQER 69
Query: 93 FHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNKR 152
F ++ +Y R + ++VYDITN SF W+ ++ DV M+LGNK D+++KR
Sbjct: 70 FRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKR 129
Query: 153 QVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVA 189
QV+ E+GE+ + + + F+ETSAK NV+ F +A
Sbjct: 130 QVSKERGEKLALDYGIKFMETSAKANINVENAFFTLA 166
>gi|106507164 RAB12, member RAS oncogene family [Homo sapiens]
Length = 244
Score = 135 bits (340), Expect = 3e-32
Identities = 63/164 (38%), Positives = 110/164 (67%), Gaps = 1/164 (0%)
Query: 31 KSKLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQ 90
K +++ +G + VGKTS++ RF ++F AC++TVG+DF KT+ L + ++LQ+WDTAGQ
Sbjct: 42 KLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQ 101
Query: 91 ERFHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDN 150
ERF+S+ +Y R + ++VYDIT +F + KW++ + +D ++L+GNK+D +
Sbjct: 102 ERFNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCET 161
Query: 151 KRQVTAEQGEEKSRNLNVM-FIETSAKTGYNVKKLFRRVASALL 193
R++T +QGE+ ++ + M F E SAK +NV ++F ++ +L
Sbjct: 162 DREITRQQGEKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDIL 205
>gi|4506367 RAB3A, member RAS oncogene family [Homo sapiens]
Length = 220
Score = 134 bits (338), Expect = 5e-32
Identities = 64/160 (40%), Positives = 102/160 (63%)
Query: 33 KLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQER 92
K+L +G SVGKTS + R+ +SF A +TVGIDF KT+Y D+ ++LQ+WDTAGQER
Sbjct: 24 KILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQER 83
Query: 93 FHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNKR 152
+ ++ +Y R + +++YDITN SF W ++ D+ ++L+GNK D++++R
Sbjct: 84 YRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDER 143
Query: 153 QVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASAL 192
V++E+G + + +L F E SAK NVK+ F R+ +
Sbjct: 144 VVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVI 183
>gi|50234889 RAB43 protein [Homo sapiens]
Length = 212
Score = 134 bits (338), Expect = 5e-32
Identities = 67/168 (39%), Positives = 106/168 (63%), Gaps = 1/168 (0%)
Query: 33 KLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQER 92
KL+ +G+ SVGKT ++ RF +F +T+G+DF KT+ ++ + V+LQ+WDTAGQER
Sbjct: 20 KLVLVGDASVGKTCVVQRFKTGAFSERQGSTIGVDFTMKTLEIQGKRVKLQIWDTAGQER 79
Query: 93 FHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNKR 152
F ++ SY R + A++ YDIT +SF W+E VR G ++V +L+GNK DL R
Sbjct: 80 FRTITQSYYRSANGAILAYDITKRSSFLSVPHWIEDVRKYAGSNIVQLLIGNKSDLSELR 139
Query: 153 QVTAEQGEEKSRNLNVM-FIETSAKTGYNVKKLFRRVASALLSTRTSP 199
+V+ + + + + +++ IETSAK NV++ F RVA+ L+ P
Sbjct: 140 EVSLAEAQSLAEHYDILCAIETSAKDSSNVEEAFLRVATELIMRHGGP 187
>gi|54859685 RAB37, member RAS oncogene family isoform 2 [Homo
sapiens]
Length = 223
Score = 134 bits (336), Expect = 8e-32
Identities = 78/191 (40%), Positives = 111/191 (58%), Gaps = 3/191 (1%)
Query: 33 KLLFLGEQSVGKTSIISRFMYNSF-GCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQE 91
K++ LG+ VGKT + +F +F ATVGIDF +K + ++ V+LQ+WDTAGQE
Sbjct: 31 KVMLLGDTGVGKTCFLIQFKDGAFLSGTFIATVGIDFRNKVVTVDGVRVKLQIWDTAGQE 90
Query: 92 RFHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNK 151
RF S+ +Y RD+ +++YDITN +SF W+ + DVVIMLLGNK D+ ++
Sbjct: 91 RFRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQRDVVIMLLGNKADMSSE 150
Query: 152 RQVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALLSTRTSPPPKEGTVEIELE 211
R + +E GE +R V F+ETSAKTG NV+ F +A L R E + +I +
Sbjct: 151 RVIRSEDGETLAREYGVPFLETSAKTGMNVELAFLAIAKE-LKYRAGHQADEPSFQIR-D 208
Query: 212 SFEESGNRSYC 222
E RS C
Sbjct: 209 YVESQKKRSSC 219
>gi|19923985 RAB3C, member RAS oncogene family [Homo sapiens]
Length = 227
Score = 133 bits (335), Expect = 1e-31
Identities = 63/160 (39%), Positives = 100/160 (62%)
Query: 33 KLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQER 92
KLL +G SVGKTS + R+ +SF A +TVGIDF KT++ ++ ++LQ+WDTAGQER
Sbjct: 32 KLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQER 91
Query: 93 FHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNKR 152
+ ++ +Y R + +++YDITN SF W ++ D+ ++L+GNK D++++R
Sbjct: 92 YRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDMEDER 151
Query: 153 QVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASAL 192
++ E+G+ L F ETSAK NVK+ F R+ +
Sbjct: 152 VISTERGQHLGEQLGFEFFETSAKDNINVKQTFERLVDII 191
>gi|21361418 RAB30, member RAS oncogene family [Homo sapiens]
Length = 203
Score = 133 bits (335), Expect = 1e-31
Identities = 70/181 (38%), Positives = 108/181 (59%), Gaps = 9/181 (4%)
Query: 33 KLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQER 92
K++ +G VGKT ++ RF F AT+G+DF+ KT+ + + V+LQ+WDTAGQER
Sbjct: 11 KIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQER 70
Query: 93 FHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNKR 152
F S+ SY R + ++ YDIT SF+ +W+ + + V+ +L+GNKIDL +R
Sbjct: 71 FRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERR 130
Query: 153 QVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALLSTR---------TSPPPKE 203
+V+ ++ EE S ++ ++ETSAK NV+KLF +A L+S +SP P E
Sbjct: 131 EVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNNVSSPLPGE 190
Query: 204 G 204
G
Sbjct: 191 G 191
>gi|4759000 RAB3D, member RAS oncogene family [Homo sapiens]
Length = 219
Score = 133 bits (335), Expect = 1e-31
Identities = 66/160 (41%), Positives = 99/160 (61%)
Query: 33 KLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQER 92
KLL +G SVGKTS + R+ +SF A +TVGIDF KT+Y D+ ++LQ+WDTAGQER
Sbjct: 24 KLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQER 83
Query: 93 FHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNKR 152
+ ++ +Y R + +++YDI N SF W ++ D+ ++L+GNK DL+++R
Sbjct: 84 YRTITTAYYRGAMGFLLMYDIANQESFAAVQDWATQIKTYSWDNAQVILVGNKCDLEDER 143
Query: 153 QVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASAL 192
V AE G + +L F E SAK NVK++F R+ +
Sbjct: 144 VVPAEDGRRLADDLGFEFFEASAKENINVKQVFERLVDVI 183
>gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo
sapiens]
Length = 216
Score = 133 bits (334), Expect = 1e-31
Identities = 77/191 (40%), Positives = 111/191 (58%), Gaps = 3/191 (1%)
Query: 33 KLLFLGEQSVGKTSIISRFMYNSF-GCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQE 91
K + +G+ VGKTS++ +F F + ATVGI F +K + ++ V+LQ+WDTAGQE
Sbjct: 24 KTILVGDSGVGKTSLLVQFDQGKFIPGSFSATVGIGFTNKVVTVDGVRVKLQIWDTAGQE 83
Query: 92 RFHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNK 151
RF S+ +Y RD+ +++YDITN +SF W+ + DVVIMLLGNK D+ ++
Sbjct: 84 RFRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQRDVVIMLLGNKADMSSE 143
Query: 152 RQVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALLSTRTSPPPKEGTVEIELE 211
R + +E GE +R V F+ETSAKTG NV+ F +A L R E + +I +
Sbjct: 144 RVIRSEDGETLAREYGVPFLETSAKTGMNVELAFLAIAKE-LKYRAGHQADEPSFQIR-D 201
Query: 212 SFEESGNRSYC 222
E RS C
Sbjct: 202 YVESQKKRSSC 212
>gi|10190714 RAS-related protein RAB-22A [Homo sapiens]
Length = 194
Score = 130 bits (328), Expect = 7e-31
Identities = 67/195 (34%), Positives = 112/195 (57%), Gaps = 2/195 (1%)
Query: 28 SLCKSKLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDT 87
+L + K+ LG+ VGK+SI+ RF+ +SF T+G F++KT+ ++++ + +WDT
Sbjct: 2 ALRELKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDT 61
Query: 88 AGQERFHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKID 147
AGQERF +L P Y R S A++VYDIT +F WV+ +R ++V+ + GNK D
Sbjct: 62 AGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVKELRQHGPPNIVVAIAGNKCD 121
Query: 148 LDNKRQVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALLSTRTSPPPKEGTVE 207
L + R+V ++ + +++ +F+ETSAK N+ +LF ++ + ST + P G
Sbjct: 122 LIDVREVMERDAKDYADSIHAIFVETSAKNAININELFIEISRRIPSTDANLP--SGGKG 179
Query: 208 IELESFEESGNRSYC 222
+L RS C
Sbjct: 180 FKLRRQPSEPKRSCC 194
>gi|7661922 RAB21, member RAS oncogene family [Homo sapiens]
Length = 225
Score = 130 bits (326), Expect = 1e-30
Identities = 68/182 (37%), Positives = 108/182 (59%), Gaps = 5/182 (2%)
Query: 14 GGFGLEAAERTEYQSLCKSKLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTM 73
GG G AA R K++ LGE VGKTS++ R+ N F T+ FL+K +
Sbjct: 7 GGGGAAAAGRAY-----SFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKL 61
Query: 74 YLEDQIVQLQLWDTAGQERFHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAER 133
+ + V L +WDTAGQERFH+L P Y RDS A++VYDIT+ +SF++ WV+ +R
Sbjct: 62 NIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKML 121
Query: 134 GDDVVIMLLGNKIDLDNKRQVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALL 193
G+++ + ++GNKIDL+ +R V+ ++ E + ++ TSAK +++LF + ++
Sbjct: 122 GNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMI 181
Query: 194 ST 195
T
Sbjct: 182 ET 183
>gi|4506363 RAB13, member RAS oncogene family [Homo sapiens]
Length = 203
Score = 129 bits (325), Expect = 2e-30
Identities = 64/161 (39%), Positives = 102/161 (63%)
Query: 33 KLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQER 92
KLL +G+ VGKT +I RF ++F +T+GIDF +T+ +E + ++LQ+WDTAGQER
Sbjct: 10 KLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQER 69
Query: 93 FHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNKR 152
F ++ +Y R + ++VYDIT+ SF+ W++ ++ V +LLGNK D++ KR
Sbjct: 70 FKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKR 129
Query: 153 QVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALL 193
+V EQ ++ +R + F ETSAK+ NV + F +A +L
Sbjct: 130 KVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDIL 170
>gi|19923750 RAB3B, member RAS oncogene family [Homo sapiens]
Length = 219
Score = 129 bits (324), Expect = 2e-30
Identities = 63/160 (39%), Positives = 99/160 (61%)
Query: 33 KLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQER 92
KLL +G SVGKTS + R+ ++F A +TVGIDF KT+Y ++ V+LQ+WDTAGQER
Sbjct: 24 KLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQER 83
Query: 93 FHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNKR 152
+ ++ +Y R + +++YDITN SF W ++ D+ ++L+GNK D++ +R
Sbjct: 84 YRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEER 143
Query: 153 QVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASAL 192
V E+G+ + L F E SAK +V++ F R+ A+
Sbjct: 144 VVPTEKGQLLAEQLGFDFFEASAKENISVRQAFERLVDAI 183
>gi|46361978 RAB26, member RAS oncogene family [Homo sapiens]
Length = 256
Score = 128 bits (321), Expect = 4e-30
Identities = 69/172 (40%), Positives = 103/172 (59%), Gaps = 2/172 (1%)
Query: 33 KLLFLGEQSVGKTSIISRFMYNSFGCACQ-ATVGIDFLSKTMYLEDQIVQLQLWDTAGQE 91
K++ +G+ VGKT ++ RF +F +TVGIDF +K + ++ V+LQ+WDTAGQE
Sbjct: 65 KVMLVGDSGVGKTCLLVRFKDGAFLAGTFISTVGIDFRNKVLDVDGVKVKLQMWDTAGQE 124
Query: 92 RFHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNK 151
RF S+ +Y RD+ +++YD+TN SF W+ + DV +MLLGNK+D ++
Sbjct: 125 RFRSVTHAYYRDAHALLLLYDVTNKASFDNIQAWLTEIHEYAQHDVALMLLGNKVDSAHE 184
Query: 152 RQVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALLSTRTSPPPKE 203
R V E GE+ ++ + F+ETSAKTG NV F +A L R+ P E
Sbjct: 185 RVVKREDGEKLAKEYGLPFMETSAKTGLNVDLAFTAIAKE-LKQRSMKAPSE 235
>gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene
family [Homo sapiens]
Length = 327
Score = 127 bits (318), Expect = 1e-29
Identities = 63/161 (39%), Positives = 100/161 (62%)
Query: 33 KLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQER 92
KLL +G+ VGKT +I RF ++F +T+GIDF +T+ +E + ++LQ+WDTAGQER
Sbjct: 134 KLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQER 193
Query: 93 FHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNKR 152
F ++ +Y R + ++ YDIT+ SF+ W++ + V +LLGNK D++ KR
Sbjct: 194 FKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSIMENASAGVEHLLLGNKCDMEAKR 253
Query: 153 QVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALL 193
+V EQ ++ +R + F ETSAK+ NV + F +A +L
Sbjct: 254 KVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDIL 294
>gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens]
Length = 327
Score = 127 bits (318), Expect = 1e-29
Identities = 63/161 (39%), Positives = 100/161 (62%)
Query: 33 KLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQER 92
KLL +G+ VGKT +I RF ++F +T+GIDF +T+ +E + ++LQ+WDTAGQER
Sbjct: 134 KLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQER 193
Query: 93 FHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNKR 152
F ++ +Y R + ++ YDIT+ SF+ W++ + V +LLGNK D++ KR
Sbjct: 194 FKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSIMENASAGVEHLLLGNKCDMEAKR 253
Query: 153 QVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALL 193
+V EQ ++ +R + F ETSAK+ NV + F +A +L
Sbjct: 254 KVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDIL 294
>gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens]
Length = 327
Score = 127 bits (318), Expect = 1e-29
Identities = 63/161 (39%), Positives = 100/161 (62%)
Query: 33 KLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYLEDQIVQLQLWDTAGQER 92
KLL +G+ VGKT +I RF ++F +T+GIDF +T+ +E + ++LQ+WDTAGQER
Sbjct: 134 KLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQER 193
Query: 93 FHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIMLLGNKIDLDNKR 152
F ++ +Y R + ++ YDIT+ SF+ W++ + V +LLGNK D++ KR
Sbjct: 194 FKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSIMENASAGVEHLLLGNKCDMEAKR 253
Query: 153 QVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALL 193
+V EQ ++ +R + F ETSAK+ NV + F +A +L
Sbjct: 254 KVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDIL 294
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,521,616
Number of Sequences: 37866
Number of extensions: 268000
Number of successful extensions: 1049
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 183
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 703
Number of HSP's gapped (non-prelim): 230
length of query: 222
length of database: 18,247,518
effective HSP length: 98
effective length of query: 124
effective length of database: 14,536,650
effective search space: 1802544600
effective search space used: 1802544600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.