Search of human proteins with 73858572

Search of human proteins with 73858572

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|73858572 matrix metalloproteinase 12 preproprotein [Homo
sapiens]
         (470 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|73858572 matrix metalloproteinase 12 preproprotein [Homo sapi...   983   0.0  
gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]    495   e-140
gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]   477   e-134
gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [H...   454   e-128
gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]    442   e-124
gi|73808268 matrix metalloproteinase 27 [Homo sapiens]                439   e-123
gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]      427   e-120
gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]   425   e-119
gi|45359865 matrix metalloproteinase 20 preproprotein [Homo sapi...   403   e-112
gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]   324   1e-88
gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein ...   300   2e-81
gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]   295   5e-80
gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]   290   1e-78
gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]    238   7e-63
gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein...   234   1e-61
gi|112382270 matrix metalloproteinase 17 preproprotein [Homo sap...   233   4e-61
gi|11968059 matrix metalloproteinase 25 preproprotein [Homo sapi...   227   2e-59
gi|58331148 matrix metalloproteinase 11 preproprotein [Homo sapi...   223   4e-58
gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprot...   207   2e-53
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]      191   1e-48
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [...   191   1e-48
gi|73808266 matrix metalloproteinase 26 preproprotein [Homo sapi...   191   1e-48
gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein ...   190   2e-48
gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]   153   4e-37
gi|22218341 matrix metalloproteinase 21 preproprotein [Homo sapi...   142   5e-34
gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens]           80   4e-15
gi|5902004 matrix metalloproteinase 23B precursor [Homo sapiens]       80   4e-15
gi|169203660 PREDICTED: similar to hCG2042634 [Homo sapiens]           79   7e-15
gi|169202084 PREDICTED: similar to hCG2042634 [Homo sapiens]           77   3e-14
gi|239750339 PREDICTED: hypothetical protein XP_002347374 [Homo ...    73   5e-13

>gi|73858572 matrix metalloproteinase 12 preproprotein [Homo
           sapiens]
          Length = 470

 Score =  983 bits (2540), Expect = 0.0
 Identities = 470/470 (100%), Positives = 470/470 (100%)

Query: 1   MKFLLILLLQATASGALPLNSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNLM 60
           MKFLLILLLQATASGALPLNSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNLM
Sbjct: 1   MKFLLILLLQATASGALPLNSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNLM 60

Query: 61  KEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPVWRKHYITYRINN 120
           KEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPVWRKHYITYRINN
Sbjct: 61  KEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPVWRKHYITYRINN 120

Query: 121 YTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGI 180
           YTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGI
Sbjct: 121 YTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGI 180

Query: 181 LAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTY 240
           LAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTY
Sbjct: 181 LAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTY 240

Query: 241 KYVDINTFRLSADDIRGIQSLYGDPKENQRLPNPDNSEPALCDPNLSFDAVTTVGNKIFF 300
           KYVDINTFRLSADDIRGIQSLYGDPKENQRLPNPDNSEPALCDPNLSFDAVTTVGNKIFF
Sbjct: 241 KYVDINTFRLSADDIRGIQSLYGDPKENQRLPNPDNSEPALCDPNLSFDAVTTVGNKIFF 300

Query: 301 FKDRFFWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRP 360
           FKDRFFWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRP
Sbjct: 301 FKDRFFWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRP 360

Query: 361 EPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITK 420
           EPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITK
Sbjct: 361 EPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITK 420

Query: 421 NFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC 470
           NFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC
Sbjct: 421 NFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC 470


>gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]
          Length = 477

 Score =  495 bits (1274), Expect = e-140
 Identities = 246/479 (51%), Positives = 329/479 (68%), Gaps = 11/479 (2%)

Query: 1   MKFLLILLLQATA-SGALPLNSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNL 59
           MK L ILLL   A   A PL+ +   E  ++   ++YLE +Y L+ +     + K SG +
Sbjct: 1   MKSLPILLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPV 60

Query: 60  MKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPVWRKHYITYRIN 119
           +K KI+EMQ FLGL+VTG+LD+ TLE+M  PRCGVPDV HFR  PG P WRK ++TYRI 
Sbjct: 61  VK-KIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIV 119

Query: 120 NYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGG 179
           NYTPD+ ++ VD A+ KA +VW  VTPL FS++  G ADI++ FA   HGDF+ FDG G 
Sbjct: 120 NYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGN 179

Query: 180 ILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPT 239
           +LAHA+ PG GI GDAHFD+DE WT  + GTNLFL A HEIGHSLGL HS++ +A+M+P 
Sbjct: 180 VLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPL 239

Query: 240 Y-KYVDINTFRLSADDIRGIQSLYGDPKENQRLP-------NPDNSEPALCDPNLSFDAV 291
           Y    D+  FRLS DDI GIQSLYG P ++   P        P+   PA CDP LSFDAV
Sbjct: 240 YHSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGTPANCDPALSFDAV 299

Query: 292 TTVGNKIFFFKDRFFWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDK 351
           +T+  +I  FKDR FW K   + +  ++LISS WP+LPSG++AAYE+ +++ VF+FK ++
Sbjct: 300 STLRGEILIFKDRHFWRKSLRKLEPELHLISSFWPSLPSGVDAAYEVTSKDLVFIFKGNQ 359

Query: 352 YWLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMD 411
           +W I        YP+ IH+ GFP  V+KIDAA+ +    +TYFFV+++YWR+DE+R  M+
Sbjct: 360 FWAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSME 419

Query: 412 PGYPKLITKNFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC 470
           PG+PK I ++F GI  KIDAVF  +  ++YFF GS+Q E+D   +++T TLKSNSW  C
Sbjct: 420 PGFPKQIAEDFPGIDSKIDAVF-EEFGFFYFFTGSSQLEFDPNAKKVTHTLKSNSWLNC 477


>gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]
          Length = 476

 Score =  477 bits (1227), Expect = e-134
 Identities = 235/478 (49%), Positives = 318/478 (66%), Gaps = 11/478 (2%)

Query: 1   MKFLLILLLQATASGALPLNSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNLM 60
           M    ++LL      A PL+ +   E +N    ++YLEK+Y LE +     +     NL+
Sbjct: 2   MHLAFLVLLCLPVCSAYPLSGAAKEEDSNKDLAQQYLEKYYNLEKDVKQFRRK--DSNLI 59

Query: 61  KEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPVWRKHYITYRINN 120
            +KIQ MQ FLGL+VTG+LDT TLE+M  PRCGVPDV HF   PG P WRK ++TYRI N
Sbjct: 60  VKKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRIVN 119

Query: 121 YTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGI 180
           YTPD+ R+ VD AI KA +VW  VTPL FS++  G ADI++ FA   HGDF++FDG G  
Sbjct: 120 YTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPGHS 179

Query: 181 LAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTY 240
           LAHA+ PG G+ GD HFD+DE WT  + GTNLFL A HE+GHSLGL HS++ +A+M+P Y
Sbjct: 180 LAHAYPPGPGLYGDIHFDDDEKWTEDASGTNLFLVAAHELGHSLGLFHSANTEALMYPLY 239

Query: 241 -KYVDINTFRLSADDIRGIQSLYGDPKENQRLP------NPDNSE-PALCDPNLSFDAVT 292
             + ++  FRLS DD+ GIQSLYG P  +   P       P  SE PA CDP LSFDA++
Sbjct: 240 NSFTELAQFRLSQDDVNGIQSLYGPPPASTEEPLVPTKSVPSGSEMPAKCDPALSFDAIS 299

Query: 293 TVGNKIFFFKDRFFWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKY 352
           T+  +  FFKDR+FW +    P+   +LIS+ WP+LPS ++AAYE+ +R+ VF+FK +++
Sbjct: 300 TLRGEYLFFKDRYFWRRSHWNPEPEFHLISAFWPSLPSYLDAAYEVNSRDTVFIFKGNEF 359

Query: 353 WLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDP 412
           W I     +  YP+ IH+ GFP  ++KIDAAV +    +TYFF  ++YWR+DE  Q M+ 
Sbjct: 360 WAIRGNEVQAGYPRGIHTLGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQ 419

Query: 413 GYPKLITKNFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC 470
           G+P+LI  +F G+ PK+DAV  +   ++YFF GS+QFE+D   + +T  LKSNSW  C
Sbjct: 420 GFPRLIADDFPGVEPKVDAVLQAFG-FFYFFSGSSQFEFDPNARMVTHILKSNSWLHC 476


>gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [Homo
           sapiens]
          Length = 469

 Score =  454 bits (1168), Expect = e-128
 Identities = 231/468 (49%), Positives = 306/468 (65%), Gaps = 9/468 (1%)

Query: 4   LLILLLQATASGALPLNSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNLMKEK 63
           LL+LL     S + P    T  ++ +V   ++YLEK+Y L+ +   V K + SG ++ EK
Sbjct: 7   LLLLLFWGVVSHSFPATLET--QEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPVV-EK 63

Query: 64  IQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPVWRKHYITYRINNYTP 123
           +++MQ F GLKVTG+ D  TL++M  PRCGVPDV  F    G P W + ++TYRI NYTP
Sbjct: 64  LKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTP 123

Query: 124 DMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILAH 183
           D+ R DVD+AI KAFQ+WSNVTPL F+K++ G ADI++ F RG H D   FDG GG LAH
Sbjct: 124 DLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAH 183

Query: 184 AFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYV 243
           AF PG GIGGDAHFDEDE WT +    NL   A HE+GHSLGL HS+D  A+M+P+Y + 
Sbjct: 184 AFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTF- 242

Query: 244 DINTFRLSADDIRGIQSLYGDPKENQRLPNPDNSEPALCDPNLSFDAVTTVGNKIFFFKD 303
                +L+ DDI GIQ++YG  +   +   P    P  CD  L+FDA+TT+  ++ FFKD
Sbjct: 243 -SGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQT--PKACDSKLTFDAITTIRGEVMFFKD 299

Query: 304 RFFWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRPEPN 363
           RF+       P+  +N IS  WP LP+G+EAAYE   R++V  FK +KYW +        
Sbjct: 300 RFYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHG 359

Query: 364 YPKSIH-SFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNF 422
           YPK I+ SFGFP  VK IDAA+      +TYFFV N+YWRYDE ++ MDPGYPK+I  +F
Sbjct: 360 YPKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDF 419

Query: 423 QGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC 470
            GIG K+DAVF  K+ ++YFF G+ Q+++D   +RI    K+NSWF C
Sbjct: 420 PGIGHKVDAVF-MKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNC 466


>gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]
          Length = 467

 Score =  442 bits (1137), Expect = e-124
 Identities = 221/465 (47%), Positives = 301/465 (64%), Gaps = 10/465 (2%)

Query: 6   ILLLQATASGALPLNSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNLMKEKIQ 65
           +LLL    S A P++S    EKN     + YLEKFY L  N+   T+ K   N++ EK++
Sbjct: 10  LLLLHVQISKAFPVSSK---EKNTKTVQD-YLEKFYQLPSNQYQSTR-KNGTNVIVEKLK 64

Query: 66  EMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPVWRKHYITYRINNYTPDM 125
           EMQ F GL VTG+ +  TL+MM  PRCGVPD   F   PG P W +  +TYRI NYTP +
Sbjct: 65  EMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRNYTPQL 124

Query: 126 NREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILAHAF 185
           +  +V+ AI+ AF++WS  +PL F++I+ G ADI + F +  HGD   FDG  GILAHAF
Sbjct: 125 SEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGILAHAF 184

Query: 186 GPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDI 245
            PG GIGGDAHFD +E WT  S   NLFL A HE GHSLGL HSSDP A+M+P Y + + 
Sbjct: 185 QPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRET 244

Query: 246 NTFRLSADDIRGIQSLYGDPKENQRLPNPDNSEPALCDPNLSFDAVTTVGNKIFFFKDRF 305
           + + L  DDI GIQ++YG      +   P   +P  CDP+L+FDA+TT+  +I FFKDR+
Sbjct: 245 SNYSLPQDDIDGIQAIYGLSSNPIQPTGPSTPKP--CDPSLTFDAITTLRGEILFFKDRY 302

Query: 306 FWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRPEPNYP 365
           FW +  +  +  +N IS  WP+LP+GI+AAYE   R+ +FLFK ++YW +S       YP
Sbjct: 303 FWRRHPQLQRVEMNFISLFWPSLPTGIQAAYEDFDRDLIFLFKGNQYWALSGYDILQGYP 362

Query: 366 KSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGI 425
           K I ++GFP+ V+ IDAAVF     +TYFFV++Q+WRYD +RQ M+PGYPK I+  F GI
Sbjct: 363 KDISNYGFPSSVQAIDAAVFYRS--KTYFFVNDQFWRYDNQRQFMEPGYPKSISGAFPGI 420

Query: 426 GPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC 470
             K+DAVF  ++ +++ F G   + +D + QR+T+  + N W  C
Sbjct: 421 ESKVDAVFQQEH-FFHVFSGPRYYAFDLIAQRVTRVARGNKWLNC 464


>gi|73808268 matrix metalloproteinase 27 [Homo sapiens]
          Length = 513

 Score =  439 bits (1130), Expect = e-123
 Identities = 229/472 (48%), Positives = 306/472 (64%), Gaps = 12/472 (2%)

Query: 2   KFLLILLLQATASGALPLNSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNLMK 61
           + LL+ L   T S A PL   T  E+N  L  + YL +FY LEI    + + K + +L+ 
Sbjct: 3   RLLLLFLFFITFSSAFPLVRMTENEENMQL-AQAYLNQFYSLEIEGNHLVQSK-NRSLID 60

Query: 62  EKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFR-EMPGGPVWRKHYITYRINN 120
           +KI+EMQ F GL VTG+LD++TLE+M  PRCGVPDV  +   +PG   WRK+ +TYRI N
Sbjct: 61  DKIREMQAFFGLTVTGKLDSNTLEIMKTPRCGVPDVGQYGYTLPG---WRKYNLTYRIIN 117

Query: 121 YTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDF-HAFDGKGG 179
           YTPDM R  VD AI++  +VWS VTPLKF+KI+ G+ADI++ F    HG     FDG  G
Sbjct: 118 YTPDMARAAVDEAIQEGLEVWSKVTPLKFTKISKGIADIMIAFRTRVHGRCPRYFDGPLG 177

Query: 180 ILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPT 239
           +L HAF PG G+GGD HFDEDE WT    G NLFL A HE GH+LGL HS+D  A+MFP 
Sbjct: 178 VLGHAFPPGPGLGGDTHFDEDENWTKDGAGFNLFLVAAHEFGHALGLSHSNDQTALMFPN 237

Query: 240 YKYVDINTFRLSADDIRGIQSLYGD-PKENQRLPNPDNSEPALCDPNLSFDAVTTVGNKI 298
           Y  +D   + LS DDI GIQS+YG  PKE  +   P  + P  CDP+L+FDA+TT   ++
Sbjct: 238 YVSLDPRKYPLSQDDINGIQSIYGGLPKEPAKPKEP--TIPHACDPDLTFDAITTFRREV 295

Query: 299 FFFKDRFFWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNL 358
            FFK R  W    +       LI+S WP+LP+ ++AAYE   R+++ +FKD+ +W+I   
Sbjct: 296 MFFKGRHLWRIYYDITDVEFELIASFWPSLPADLQAAYE-NPRDKILVFKDENFWMIRGY 354

Query: 359 RPEPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLI 418
              P+YPKSIH+ GFP  VKKIDAAV +    +TYFFV    WR+DE  Q MD G+P+ +
Sbjct: 355 AVLPDYPKSIHTLGFPGRVKKIDAAVCDKTTRKTYFFVGIWCWRFDEMTQTMDKGFPQRV 414

Query: 419 TKNFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC 470
            K+F GI  ++DA F  K  +++F +GS QFEYD   + IT+ +++N+WF C
Sbjct: 415 VKHFPGISIRVDAAFQYKG-FFFFSRGSKQFEYDIKTKNITRIMRTNTWFQC 465


>gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]
          Length = 403

 Score =  427 bits (1099), Expect = e-120
 Identities = 211/405 (52%), Positives = 270/405 (66%), Gaps = 6/405 (1%)

Query: 67  MQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPVWRKHYITYRINNYTPDMN 126
           MQ F GLKVTG+ D  TL++M  PRCGVPDV  F    G P W + ++TYRI NYTPD+ 
Sbjct: 1   MQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLP 60

Query: 127 REDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILAHAFG 186
           R DVD+AI KAFQ+WSNVTPL F+K++ G ADI++ F RG H D   FDG GG LAHAF 
Sbjct: 61  RADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQ 120

Query: 187 PGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDIN 246
           PG GIGGDAHFDEDE WT +    NL   A HE+GHSLGL HS+D  A+M+P+Y +    
Sbjct: 121 PGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTF--SG 178

Query: 247 TFRLSADDIRGIQSLYGDPKENQRLPNPDNSEPALCDPNLSFDAVTTVGNKIFFFKDRFF 306
             +L+ DDI GIQ++YG  +   +   P    P  CD  L+FDA+TT+  ++ FFKDRF+
Sbjct: 179 DVQLAQDDIDGIQAIYGRSQNPVQPIGPQT--PKACDSKLTFDAITTIRGEVMFFKDRFY 236

Query: 307 WLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRPEPNYPK 366
                  P+  +N IS  WP LP+G+EAAYE   R++V  FK +KYW +        YPK
Sbjct: 237 MRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPK 296

Query: 367 SIH-SFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGI 425
            I+ SFGFP  VK IDAA+      +TYFFV N+YWRYDE ++ MDPGYPK+I  +F GI
Sbjct: 297 DIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGI 356

Query: 426 GPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC 470
           G K+DAVF  K+ ++YFF G+ Q+++D   +RI    K+NSWF C
Sbjct: 357 GHKVDAVF-MKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNC 400


>gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]
          Length = 471

 Score =  425 bits (1093), Expect = e-119
 Identities = 221/468 (47%), Positives = 290/468 (61%), Gaps = 10/468 (2%)

Query: 7   LLLQATASGALPLNSS---TSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNLMKEK 63
           L L  T   ALPL S      L + ++ F ERYL  +Y    N   + K + + + M E+
Sbjct: 10  LFLSWTHCRALPLPSGGDEDDLSEEDLQFAERYLRSYYH-PTNLAGILK-ENAASSMTER 67

Query: 64  IQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPVWRKHYITYRINNYTP 123
           ++EMQ F GL+VTG+LD +TL++M  PRCGVPDV  +   P    W K  +TYRI NYTP
Sbjct: 68  LREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSKMNLTYRIVNYTP 127

Query: 124 DMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILAH 183
           DM   +V+ A +KAF+VWS+VTPL F++++ G+ADI++ F    HGDF+ FDG  G+LAH
Sbjct: 128 DMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAH 187

Query: 184 AFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYV 243
           AF PG   GGDAHFD+DE WT+ S G NLFL A HE GHSLGL HS DP A+MFP Y Y 
Sbjct: 188 AFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYT 247

Query: 244 DINTFRLSADDIRGIQSLYGDPKENQRLPNPDNSE-PALCDPNLSFDAVTTVGNKIFFFK 302
             + F L  DD++GIQSLYG   E+   PNP + + P  CDP+LS DA+T++  +   FK
Sbjct: 248 GKSHFMLPDDDVQGIQSLYGPGDED---PNPKHPKTPDKCDPSLSLDAITSLRGETMIFK 304

Query: 303 DRFFWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRPEP 362
           DRFFW    ++    + L  S WP LP+ I+AAYE  + + +F+F+  K+W ++      
Sbjct: 305 DRFFWRLHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGYDILE 364

Query: 363 NYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNF 422
            YPK I   G P  VKKI AAV      +T  F  NQ WRYD+   +MD  YP+LI ++F
Sbjct: 365 GYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDYPRLIEEDF 424

Query: 423 QGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC 470
            GIG K+DAV Y KN Y YFF G  QFEY     RI + + +NS   C
Sbjct: 425 PGIGDKVDAV-YEKNGYIYFFNGPIQFEYSIWSNRIVRVMPANSILWC 471


>gi|45359865 matrix metalloproteinase 20 preproprotein [Homo
           sapiens]
          Length = 483

 Score =  403 bits (1035), Expect = e-112
 Identities = 207/479 (43%), Positives = 293/479 (61%), Gaps = 18/479 (3%)

Query: 3   FLLILLLQATASGALPLNSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNLMKE 62
           FL++ L  +TA+ +L + +S    +NN    + YL+K+Y  +        +    N M  
Sbjct: 12  FLIMALKFSTAAPSL-VAASPRTWRNNYRLAQAYLDKYYTNKEGHQIGEMVARGSNSMIR 70

Query: 63  KIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPVWRKHYITYRINNYT 122
           KI+E+Q F GL+VTG+LD +T+ ++  PRCGVPDV ++R  PG P W+K+ +TYRI+ YT
Sbjct: 71  KIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYT 130

Query: 123 PDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILA 182
           P M+  +VD A+  A Q WS+  PL F +IN+G ADI++ F  G HGD + FDG  G LA
Sbjct: 131 PSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLA 190

Query: 183 HAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKY 242
           HAF PG G+GGD HFD  E WT  + G NLF  A HE GH+LGL HS+DP A+M+PTYKY
Sbjct: 191 HAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKY 250

Query: 243 VDINTFRLSADDIRGIQSLYGDPK---ENQRLPNPDNSEPA---LCDPNLSFDAVTTVGN 296
            +   F L  DD++GIQ+LYG  K       LP+  + +P+   LCD + SFDAVT +G 
Sbjct: 251 KNPYGFHLPKDDVKGIQALYGPRKVFLGKPTLPHAPHHKPSIPDLCDSSSSFDAVTMLGK 310

Query: 297 KIFFFKDRFFW-----LKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDK 351
           ++  FKDR FW     L+   RP T    I+S +P L S ++AAYE+  R   + FK   
Sbjct: 311 ELLLFKDRIFWRRQVHLRTGIRPST----ITSSFPQLMSNVDAAYEVAERGTAYFFKGPH 366

Query: 352 YWLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMD 411
           YW+    + +   P++I+ FGFP  V++IDAAV+     +T FFV ++Y+ YDER++ M+
Sbjct: 367 YWITRGFQMQ-GPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKME 425

Query: 412 PGYPKLITKNFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC 470
             YPK   + F G+  +IDA     N Y YFF G   ++YD   + +   +KS+SW GC
Sbjct: 426 KDYPKNTEEEFSGVNGQIDAA-VELNGYIYFFSGPKTYKYDTEKEDVVSVVKSSSWIGC 483


>gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]
          Length = 645

 Score =  324 bits (830), Expect = 1e-88
 Identities = 192/494 (38%), Positives = 259/494 (52%), Gaps = 61/494 (12%)

Query: 33  GERYLEKFYGLEINKLPVTKMKYSGNLMKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRC 92
           G+ +L K YG  +         +S   ++  +  MQ F G+ VTG LD +T+E M  PRC
Sbjct: 81  GQNWL-KSYGYLLPYDSRASALHSAKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRC 139

Query: 93  GVPDVHHF-------REMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVT 145
           GVPD  H        R    G  WR+ +ITY I+NYTP +   D   AIR+AF VW  VT
Sbjct: 140 GVPDHPHLSRRRRNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVT 199

Query: 146 PLKFSKI-------NTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFD 198
           PL F ++       +   ADI++ FA G HGD   FDG+GG LAHA+ PG GIGGD HFD
Sbjct: 200 PLTFEEVPYHEIKSDRKEADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFD 259

Query: 199 EDEFWT---THSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDI 255
            DE WT    +  G +LFL AVHE+GH+LGL HSSDP A+M P Y+Y++ + F+L  DD+
Sbjct: 260 SDEPWTLGNANHDGNDLFLVAVHELGHALGLEHSSDPSAIMAPFYQYMETHNFKLPQDDL 319

Query: 256 RGIQSLYGDPKE-----------------------NQRLPNP-----------DNSEPAL 281
           +GIQ +YG P E                       ++R P P             ++P +
Sbjct: 320 QGIQKIYGPPAEPLEPTRPLPTLPVRRIHSPSERKHERQPRPPRPPLGDRPSTPGTKPNI 379

Query: 282 CDPNLSFDAVTTVGNKIFFFKDRFFWLKVSERPKTSVNL-ISSLWPTLPSGIEAAYEIEA 340
           CD N  F+ V     ++F FKDR+FW   + R +    + I   W  LP+ I+AAYE  A
Sbjct: 380 CDGN--FNTVALFRGEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYE-RA 436

Query: 341 RNQVFLFKDDKYWLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQY 400
             +   FK DKYW+   +  EP YP S+   G     + ID A+      +TYFF   +Y
Sbjct: 437 DGRFVFFKGDKYWVFKEVTVEPGYPHSLGELGSCLPREGIDTALRWEPVGKTYFFKGERY 496

Query: 401 WRYDERRQMMDPGYPKLITKNFQGIGPKIDAVFYSKNKYY-YFFQGSNQFEYDFLLQRIT 459
           WRY E R+  DPGYPK IT  ++GI       F SK  YY YF++G + +++D     + 
Sbjct: 497 WRYSEERRATDPGYPKPITV-WKGIPQAPQGAFISKEGYYTYFYKGRDYWKFDNQKLSVE 555

Query: 460 KTLKSN---SWFGC 470
                N    W GC
Sbjct: 556 PGYPRNILRDWMGC 569


>gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein
           [Homo sapiens]
          Length = 607

 Score =  300 bits (767), Expect = 2e-81
 Identities = 176/473 (37%), Positives = 255/473 (53%), Gaps = 59/473 (12%)

Query: 34  ERYLEKFYGLEINKLPVTKMKYSGNLMKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCG 93
           E +L+K YG      P   +  S   M+  +  MQ F G+ +TG++D +T++ M  PRCG
Sbjct: 44  EVWLQK-YGYLPPTDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCG 102

Query: 94  VPD---------VHHFREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNV 144
           VPD         +   R    G  W+  +ITY I N TP +   +   AIR+AF VW NV
Sbjct: 103 VPDQTRGSSKFHIRRKRYALTGQKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNV 162

Query: 145 TPLKF-----SKINTGM--ADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHF 197
           TPL F     S++  G    DI ++FA G HGD   FDG+GG LAHA+ PG GIGGD HF
Sbjct: 163 TPLTFEEVPYSELENGKRDVDITIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHF 222

Query: 198 DEDEFWTT---HSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADD 254
           D DE WT    +  G +LFL AVHE+GH+LGL HS+DP A+M P Y+Y++ + F+L  DD
Sbjct: 223 DSDEPWTLGNPNHDGNDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPNDD 282

Query: 255 IRGIQSLYG------------------------DPKENQR---------LPNPDNSEPAL 281
           ++GIQ +YG                        DP++N R          P+   ++P +
Sbjct: 283 LQGIQKIYGPPDKIPPPTRPLPTVPPHRSIPPADPRKNDRPKPPRPPTGRPSYPGAKPNI 342

Query: 282 CDPNLSFDAVTTVGNKIFFFKDRFFWLKVSERPKTSVNL-ISSLWPTLPSGIEAAYEIEA 340
           CD N  F+ +  +  ++F FKD++FW   + R      + I+  W  LP  I+A YE   
Sbjct: 343 CDGN--FNTLAILRREMFVFKDQWFWRVRNNRVMDGYPMQITYFWRGLPPSIDAVYENSD 400

Query: 341 RNQVFLFKDDKYWLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQY 400
            N VF FK +KYW+  +   +P YP  + + G       ID+A++     +TYFF  ++Y
Sbjct: 401 GNFVF-FKGNKYWVFKDTTLQPGYPHDLITLGSGIPPHGIDSAIWWEDVGKTYFFKGDRY 459

Query: 401 WRYDERRQMMDPGYPKLITKNFQGIGPKIDAVF-YSKNKYYYFFQGSNQFEYD 452
           WRY E  + MDPGYPK IT  ++GI       F + +N + YF++G   ++++
Sbjct: 460 WRYSEEMKTMDPGYPKPITV-WKGIPESPQGAFVHKENGFTYFYKGKEYWKFN 511


>gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]
          Length = 669

 Score =  295 bits (756), Expect = 5e-80
 Identities = 177/468 (37%), Positives = 236/468 (50%), Gaps = 75/468 (16%)

Query: 56  SGNLMKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPG---------- 105
           S  ++   + EMQ F G+ VTG LD  T E M  PRCGVPD    R              
Sbjct: 75  SAQILASALAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVRVKANLRRRRKRYAL 134

Query: 106 -GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKI--------NTGM 156
            G  W  H++T+ I NYT  +       A+R+AF+VW   TPL F ++            
Sbjct: 135 TGRKWNNHHLTFSIQNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKE 194

Query: 157 ADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWT---THSGGTNLF 213
           ADI+V+FA G HGD   FDG GG LAHA+ PG G+GGD HFD DE WT   T   G NLF
Sbjct: 195 ADIMVLFASGFHGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEPWTFSSTDLHGNNLF 254

Query: 214 LTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLY----GDPKENQ 269
           L AVHE+GH+LGL HSS+P A+M P Y++ D++ F+L  DD+RGIQ LY    G P+  Q
Sbjct: 255 LVAVHELGHALGLEHSSNPNAIMAPFYQWKDVDNFKLPEDDLRGIQQLYGTPDGQPQPTQ 314

Query: 270 RLP-------------------------------------------NPDNSEPALCDPNL 286
            LP                                            PD   P +CD + 
Sbjct: 315 PLPTVTPRRPGRPDHRPPRPPQPPPPGGKPERPPKPGPPVQPRATERPDQYGPNICDGD- 373

Query: 287 SFDAVTTVGNKIFFFKDRFFWLKVSERPKTSVNL-ISSLWPTLPSGIEAAYEIEARNQVF 345
            FD V  +  ++F FK R+FW     R   +  + I   W  LP  I AAYE +    VF
Sbjct: 374 -FDTVAMLRGEMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPGDISAAYERQDGRFVF 432

Query: 346 LFKDDKYWLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDE 405
            FK D+YWL      EP YP+ + S+G      +ID A++      T+FF +++YWR++E
Sbjct: 433 -FKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHTFFFQEDRYWRFNE 491

Query: 406 RRQMMDPGYPKLITKNFQGIGPKIDAVFYSKN-KYYYFFQGSNQFEYD 452
             Q  DPGYPK I+  +QGI       F S +  Y YF++G+  +++D
Sbjct: 492 ETQRGDPGYPKPISV-WQGIPASPKGAFLSNDAAYTYFYKGTKYWKFD 538


>gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]
          Length = 582

 Score =  290 bits (743), Expect = 1e-78
 Identities = 188/508 (37%), Positives = 262/508 (51%), Gaps = 52/508 (10%)

Query: 4   LLILLLQATASGALPLNSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNLMKEK 63
           LL LL   TA  +L    S+S         E +L+++  L    L  T  + S   +   
Sbjct: 12  LLPLLTLGTALASLGSAQSSSFSP------EAWLQQYGYLPPGDLR-THTQRSPQSLSAA 64

Query: 64  IQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPD---------VHHFREMPGGPVWRKHYI 114
           I  MQ F GL+VTG+ D  T++ M  PRCGVPD         V   R    G  W+ + I
Sbjct: 65  IAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQHNEI 124

Query: 115 TYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKI--------NTGMADILVVFARG 166
           T+ I NYTP +       AIRKAF+VW + TPL+F ++        +   ADI++ FA G
Sbjct: 125 TFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIFFAEG 184

Query: 167 AHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHS---GGTNLFLTAVHEIGHS 223
            HGD   FDG+GG LAHA+ PG  IGGD HFD  E WT  +    G ++FL AVHE+GH+
Sbjct: 185 FHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHELGHA 244

Query: 224 LGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG-----------DPKENQRLP 272
           LGL HSSDP A+M P Y+++D   F L  DD RGIQ LYG            P+   R  
Sbjct: 245 LGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPTKMPPQPRTTSRPS 304

Query: 273 NPDNSE-----PALCDPNLSFDAVTTVGNKIFFFKDRFFWLKVSERPKTSVNL-ISSLWP 326
            PD  +     P +CD N  FD V  +  ++F FK+R+FW   + +      + I   W 
Sbjct: 305 VPDKPKNPTYGPNICDGN--FDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQFWR 362

Query: 327 TLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFN 386
            LP+ I  AYE +    VF FK DK+W+      EP YPK I   G      KIDAA+F 
Sbjct: 363 GLPASINTAYERKDGKFVF-FKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALFW 421

Query: 387 PRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGIGPKIDAVFYSKNKYY-YFFQG 445
               +TYFF  N+Y+R++E  + +D  YPK I K ++GI       F   ++ + YF++G
Sbjct: 422 MPNGKTYFFRGNKYYRFNEELRAVDSEYPKNI-KVWEGIPESPRGSFMGSDEVFTYFYKG 480

Query: 446 SNQFEYDFLLQRITKTLKSNS---WFGC 470
           +  ++++    ++      ++   W GC
Sbjct: 481 NKYWKFNNQKLKVEPGYPKSALRDWMGC 508


>gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]
          Length = 267

 Score =  238 bits (608), Expect = 7e-63
 Identities = 118/236 (50%), Positives = 151/236 (63%), Gaps = 8/236 (3%)

Query: 36  YLEKFYGLEINKLPVTKMKYSGNLMKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVP 95
           YL++FY  +      TK   + N ++ K++EMQ F GL +TG L++  +E+M  PRCGVP
Sbjct: 38  YLKRFYLYDSE----TK---NANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVP 90

Query: 96  DVHHFREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTG 155
           DV  +   P  P W    +TYRI +YT D+    VD  + KA  +W    PL F K+  G
Sbjct: 91  DVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWG 150

Query: 156 MADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSG-GTNLFL 214
            ADI++ FARGAHGD + FDG G  LAHAF PG+G+GGDAHFDEDE WT  S  G N   
Sbjct: 151 TADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLY 210

Query: 215 TAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYGDPKENQR 270
            A HE+GHSLG+GHSSDP AVM+PTY   D   F+LS DDI+GIQ LYG    +++
Sbjct: 211 AATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRK 266


>gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein
           [Homo sapiens]
          Length = 457

 Score =  234 bits (598), Expect = 1e-61
 Identities = 139/365 (38%), Positives = 194/365 (53%), Gaps = 56/365 (15%)

Query: 34  ERYLEKFYGLEINKLPVTKMKYSGNLMKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCG 93
           E +L+K YG      P   +  S   M+  +  MQ F G+ +TG++D +T++ M  PRCG
Sbjct: 44  EVWLQK-YGYLPPTDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCG 102

Query: 94  VPD---------VHHFREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNV 144
           VPD         +   R    G  W+  +ITY I N TP +   +   AIR+AF VW NV
Sbjct: 103 VPDQTRGSSKFHIRRKRYALTGQKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNV 162

Query: 145 TPLKF-----SKINTGM--ADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHF 197
           TPL F     S++  G    DI ++FA G HGD   FDG+GG LAHA+ PG GIGGD HF
Sbjct: 163 TPLTFEEVPYSELENGKRDVDITIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHF 222

Query: 198 DEDEFWTT---HSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADD 254
           D DE WT    +  G +LFL AVHE+GH+LGL HS+DP A+M P Y+Y++ + F+L  DD
Sbjct: 223 DSDEPWTLGNPNHDGNDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPNDD 282

Query: 255 IRGIQSLYG------------------------DPKENQR---------LPNPDNSEPAL 281
           ++GIQ +YG                        DP++N R          P+   ++P +
Sbjct: 283 LQGIQKIYGPPDKIPPPTRPLPTVPPHRSIPPADPRKNDRPKPPRPPTGRPSYPGAKPNI 342

Query: 282 CDPNLSFDAVTTVGNKIFFFKDRFFWLKVSERPKTSVNL-ISSLWPTLPSGIEAAYEIEA 340
           CD N  F+ +  +  ++F FKD++FW   + R      + I+  W  LP  I+A YE   
Sbjct: 343 CDGN--FNTLAILRREMFVFKDQWFWRVRNNRVMDGYPMQITYFWRGLPPSIDAVYENSD 400

Query: 341 RNQVF 345
            N VF
Sbjct: 401 GNFVF 405


>gi|112382270 matrix metalloproteinase 17 preproprotein [Homo
           sapiens]
          Length = 603

 Score =  233 bits (593), Expect = 4e-61
 Identities = 155/484 (32%), Positives = 232/484 (47%), Gaps = 45/484 (9%)

Query: 4   LLILLLQATASGALPLNSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNLMKEK 63
           LL+LL   T  G      +   E  ++  G  +L +F G      P T    +   + + 
Sbjct: 25  LLLLLALGTRGGCAAPAPAPRAE--DLSLGVEWLSRF-GYLPPADPTTGQLQTQEELSKA 81

Query: 64  IQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDV------HHFREMPGGPVWRKHYITYR 117
           I  MQ F GL+ TG LD +TL +M  PRC +PD+         R+ P    W K  +++R
Sbjct: 82  ITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQARRRRQAPAPTKWNKRNLSWR 141

Query: 118 INNYTPD--MNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFD 175
           +  +  D  +  + V   +  A +VWS++ PL F ++    ADI + F++  H D + FD
Sbjct: 142 VRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQIDFSKADHNDGYPFD 201

Query: 176 GKGGILAHAFGPG-SGIGGDAHFDEDEFWTTHSG---GTNLFLTAVHEIGHSLGLGHSSD 231
           G GG +AHAF PG     GD HFD+DE WT  S    G +LF  AVHE GH++GL H + 
Sbjct: 202 GPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAA 261

Query: 232 PKAVMFPTYK--YVDINTFRLSADDIRGIQSLYG---------DPKENQRLPNPDNSE-- 278
             ++M P Y+    D   + L  +D   +  LYG          P+E   LP P ++   
Sbjct: 262 AHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRESVSPTAQPEEPPLLPEPPDNRSS 321

Query: 279 -------PALCDPNLSFDAVTTVGNKIFFFKDRFFWLKVSERPKTSVN--LISSLWPTLP 329
                  P  C  +  FDAV  +  + FFFK ++FW    +R   S+    +   W  LP
Sbjct: 322 APPRKDVPHRCSTH--FDAVAQIRGEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLP 379

Query: 330 ---SGIEAAYEIEARNQVFLFKDDKYWLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFN 386
                ++A YE  + +++  FK D+YW+  +   E  YP+ +  F  P     IDAA   
Sbjct: 380 LHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPVSDFSLP--PGGIDAAFSW 437

Query: 387 PRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGIGPKIDAVFYSKNKYYYFFQGS 446
               RTYFF D  YWRYD+  + MDPGYP   +  ++G+   +D      +   YFF+G 
Sbjct: 438 AHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQ-SPLWRGVPSTLDDAMRWSDGASYFFRGQ 496

Query: 447 NQFE 450
             ++
Sbjct: 497 EYWK 500


>gi|11968059 matrix metalloproteinase 25 preproprotein [Homo
           sapiens]
          Length = 562

 Score =  227 bits (578), Expect = 2e-59
 Identities = 162/492 (32%), Positives = 235/492 (47%), Gaps = 59/492 (11%)

Query: 4   LLILLLQATASGALPLNSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNLMKEK 63
           LL+LLL   A    P     SL       G  +L + YG      P      S   +++ 
Sbjct: 10  LLLLLLAPPARAPKPSAQDVSL-------GVDWLTR-YGYLPPPHPAQAQLQSPEKLRDA 61

Query: 64  IQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDV--------HHFREMPGGPVWRKHYIT 115
           I+ MQ F GL  TG++D  T+  M  PRC +PDV           R    G VW+K  +T
Sbjct: 62  IKVMQRFAGLPETGRMDPGTVATMRKPRCSLPDVLGVAGLVRRRRRYALSGSVWKKRTLT 121

Query: 116 YRINNY--TPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMA---DILVVFARGAHGD 170
           +R+ ++  +  +++E V   +  A   W   + L F ++++      DIL+ FAR  H D
Sbjct: 122 WRVRSFPQSSQLSQETVRVLMSYALMAWGMESGLTFHEVDSPQGQEPDILIDFARAFHQD 181

Query: 171 FHAFDGKGGILAHAFGPGSG-IGGDAHFDEDEFWTTHSG---GTNLFLTAVHEIGHSLGL 226
            + FDG GG LAHAF PG   I GD HFD++E WT  S    GT+LF  AVHE GH+LGL
Sbjct: 182 SYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFGSKDGEGTDLFAVAVHEFGHALGL 241

Query: 227 GHSSDPKAVMFPTYK--YVDINTFRLSADDIRGIQSLYG--------DPKENQRLPNPDN 276
           GHSS P ++M P Y+    D + +RLS DD  G+Q LYG         P      P P  
Sbjct: 242 GHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQLYGKAPQTPYDKPTRKPLAPPPQP 301

Query: 277 SEPALCDPNL--------SFDAVTTVGNKIFFFKDRFFW------LKVSERPKTSVNLIS 322
                  P+         +FDA+  +  + FFFK  +FW        VS RP      + 
Sbjct: 302 PASPTHSPSFPIPDRCEGNFDAIANIRGETFFFKGPWFWRLQPSGQLVSPRPAR----LH 357

Query: 323 SLWPTLPSG---IEAAYEIEARNQVFLFKDDKYWLISNLRPEPNYPKSIHSFGFPNFVKK 379
             W  LP+    ++AAY      ++ LF   ++W+  + + E    + +   G P   ++
Sbjct: 358 RFWEGLPAQVRVVQAAYARHRDGRILLFSGPQFWVFQDRQLEGG-ARPLTELGLPP-GEE 415

Query: 380 IDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGIGPKIDAVFYSKNKY 439
           +DA    P+  +TY     QYWRYDE     DPGYP+ ++  ++G  P  D V  S    
Sbjct: 416 VDAVFSWPQNGKTYLVRGRQYWRYDEAAARPDPGYPRDLSL-WEGAPPSPDDVTVSNAGD 474

Query: 440 YYFFQGSNQFEY 451
            YFF+G++ + +
Sbjct: 475 TYFFKGAHYWRF 486


>gi|58331148 matrix metalloproteinase 11 preproprotein [Homo
           sapiens]
          Length = 488

 Score =  223 bits (567), Expect = 4e-58
 Identities = 146/416 (35%), Positives = 212/416 (50%), Gaps = 42/416 (10%)

Query: 87  MHAPRCGVPDV--------HHFREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAF 138
           +  PRCGVPD            R +  G  W K  +TYRI  +   + +E V   + +A 
Sbjct: 75  LRPPRCGVPDPSDGLSARNRQKRFVLSGGRWEKTDLTYRILRFPWQLVQEQVRQTMAEAL 134

Query: 139 QVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFD 198
           +VWS+VTPL F++++ G ADI++ FAR  HGD   FDG GGILAHAF P +   GD HFD
Sbjct: 135 KVWSDVTPLTFTEVHEGRADIMIDFARYWHGDDLPFDGPGGILAHAFFPKTHREGDVHFD 194

Query: 199 EDEFWTT-HSGGTNLFLTAVHEIGHSLGLGHSSDPKAVM--FPTYKYVDINTFRLSADDI 255
            DE WT     GT+L   A HE GH LGL H++  KA+M  F T++Y       LS DD 
Sbjct: 195 YDETWTIGDDQGTDLLQVAAHEFGHVLGLQHTTAAKALMSAFYTFRY----PLSLSPDDC 250

Query: 256 RGIQSLYGDP-----------------KENQRLPNPDNSEPALCDPNLSFDAVTTVGNKI 298
           RG+Q LYG P                   N+  P   ++ P  C+   SFDAV+T+  ++
Sbjct: 251 RGVQHLYGQPWPTVTSRTPALGPQAGIDTNEIAPLEPDAPPDACE--ASFDAVSTIRGEL 308

Query: 299 FFFKDRFFW-LKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISN 357
           FFFK  F W L+  +       L S  W  LPS ++AA+E +A+  ++ F+  +YW+   
Sbjct: 309 FFFKAGFVWRLRGGQLQPGYPALASRHWQGLPSPVDAAFE-DAQGHIWFFQGAQYWVYDG 367

Query: 358 LRPEPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKL 417
            +P    P  +   G   F     A V+ P   + YFF    YWR+    + +D   P+ 
Sbjct: 368 EKPVLG-PAPLTELGLVRFPVHA-ALVWGPEKNKIYFFRGRDYWRFHPSTRRVDSPVPRR 425

Query: 418 ITKNFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITK---TLKSNSWFGC 470
            T +++G+  +IDA F   + Y YF +G   +++D +  +  +    L    +FGC
Sbjct: 426 AT-DWRGVPSEIDAAFQDADGYAYFLRGRLYWKFDPVKVKALEGFPRLVGPDFFGC 480


>gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprotein
           [Homo sapiens]
          Length = 508

 Score =  207 bits (527), Expect = 2e-53
 Identities = 147/429 (34%), Positives = 217/429 (50%), Gaps = 31/429 (7%)

Query: 62  EKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPV--WRKHYITYRIN 119
           E ++  Q    L V+GQLD +T   M  PRCG+ D  + + +    +  WRK ++T+RI 
Sbjct: 55  EALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRIL 114

Query: 120 NYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVF-ARGAHGDFHAFDGKG 178
           N    +       A+R+AFQ WSNV PL F ++  G ADI + F  R +    + FDG G
Sbjct: 115 NLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPG 174

Query: 179 GILAHAFGPGSGIGGDAHFDEDEFWTTHS-GGTNLFLTAVHEIGHSLGLGHSSDPKAVMF 237
            +LAHA  P     G  HFDEDEFWT  +  G NL + A HE+GH+LGLGHS   +A+M 
Sbjct: 175 RVLAHADIPEL---GSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMA 231

Query: 238 PTYKYVDINTFRLSADDIRGIQSLYG--------DPKENQRLPN--PDNSEPA-LCDPNL 286
           P Y+    + F+L  DD+ GIQ+LYG        + +E   LP   P  +EP+ + DP  
Sbjct: 232 PVYEGYRPH-FKLHPDDVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDPCS 290

Query: 287 SFDAVTTVG--NKIFFFKDRFFWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQV 344
           S      +G   K + FK  + W  VS+     +  +S+LW  LP  ++AA        +
Sbjct: 291 SELDAMMLGPRGKTYAFKGDYVW-TVSDSGPGPLFRVSALWEGLPGNLDAAVYSPRTQWI 349

Query: 345 FLFKDDKYWLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYD 404
             FK DK W   N +  P +PK ++    PN    +DAA++ P   + + F  + YW++D
Sbjct: 350 HFFKGDKVWRYINFKMSPGFPKKLNRVE-PN----LDAALYWPLNQKVFLFKGSGYWQWD 404

Query: 405 ERRQMMDPGYPKLITKNFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLK- 463
           E  +     YPK I   F G+  +  A    ++   YFF+G   +  +  L R+ K    
Sbjct: 405 ELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQDGRVYFFKGKVYWRLNQQL-RVEKGYPR 463

Query: 464 --SNSWFGC 470
             S++W  C
Sbjct: 464 NISHNWMHC 472


>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
          Length = 610

 Score =  191 bits (485), Expect = 1e-48
 Identities = 108/290 (37%), Positives = 156/290 (53%), Gaps = 22/290 (7%)

Query: 195 AHFDEDEFWT-THSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSAD 253
           A++D+D  W      G +LFL A HE GH++GL HS DP A+M P Y Y     FRLS D
Sbjct: 329 ANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYT--KNFRLSQD 386

Query: 254 DIRGIQSLYGDPKENQRLPNPDNS----EPALCDPNLSFDAVTTVGNKIFFFKDRFFWLK 309
           DI+GIQ LYG   +      P  +     P +C  ++ FD +  +  +IFFFKDRF W  
Sbjct: 387 DIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRT 446

Query: 310 VSERPKT-SVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRPEPNYPKSI 368
           V+ R K     L+++ WP LP  I+A YE     +   F  ++YW+ S    E  YPK +
Sbjct: 447 VTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPL 506

Query: 369 HSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGIGPK 428
            S G P  V+++DAA    +  +TY F  +++WRY+E ++ MDPG+PKLI   +  I   
Sbjct: 507 TSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDN 566

Query: 429 IDAVF-YSKNKYYYFFQGSNQFEYDFLLQRITKTLKS-------NSWFGC 470
           +DAV       + YFF+G+      + L+   ++LKS       + W GC
Sbjct: 567 LDAVVDLQGGGHSYFFKGA------YYLKLENQSLKSVKFGSIKSDWLGC 610



 Score =  187 bits (474), Expect = 2e-47
 Identities = 92/176 (52%), Positives = 118/176 (67%), Gaps = 11/176 (6%)

Query: 35  RYLEKFYGLEINKLPVTKMKYSGNL--MKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRC 92
           +YL  FYG           K S NL  +K+ +++MQ F GL  TG LD +T+E M  PRC
Sbjct: 2   QYLNTFYGCP---------KESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRC 52

Query: 93  GVPDVHHFREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKI 152
           G PDV ++   P  P W K+ ITYRI  YTPD++ E VD A  +AFQVWS+VTPL+FS+I
Sbjct: 53  GNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRI 112

Query: 153 NTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSG 208
           + G ADI++ F R  HGD + FDGK G+LAHAF PG+G+GGD+HFD+DE WT   G
Sbjct: 113 HDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEG 168


>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
           [Homo sapiens]
          Length = 660

 Score =  191 bits (485), Expect = 1e-48
 Identities = 108/290 (37%), Positives = 156/290 (53%), Gaps = 22/290 (7%)

Query: 195 AHFDEDEFWT-THSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSAD 253
           A++D+D  W      G +LFL A HE GH++GL HS DP A+M P Y Y     FRLS D
Sbjct: 379 ANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYT--KNFRLSQD 436

Query: 254 DIRGIQSLYGDPKENQRLPNPDNS----EPALCDPNLSFDAVTTVGNKIFFFKDRFFWLK 309
           DI+GIQ LYG   +      P  +     P +C  ++ FD +  +  +IFFFKDRF W  
Sbjct: 437 DIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRT 496

Query: 310 VSERPKT-SVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRPEPNYPKSI 368
           V+ R K     L+++ WP LP  I+A YE     +   F  ++YW+ S    E  YPK +
Sbjct: 497 VTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPL 556

Query: 369 HSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGIGPK 428
            S G P  V+++DAA    +  +TY F  +++WRY+E ++ MDPG+PKLI   +  I   
Sbjct: 557 TSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDN 616

Query: 429 IDAVF-YSKNKYYYFFQGSNQFEYDFLLQRITKTLKS-------NSWFGC 470
           +DAV       + YFF+G+      + L+   ++LKS       + W GC
Sbjct: 617 LDAVVDLQGGGHSYFFKGA------YYLKLENQSLKSVKFGSIKSDWLGC 660



 Score =  187 bits (474), Expect = 2e-47
 Identities = 92/176 (52%), Positives = 118/176 (67%), Gaps = 11/176 (6%)

Query: 35  RYLEKFYGLEINKLPVTKMKYSGNL--MKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRC 92
           +YL  FYG           K S NL  +K+ +++MQ F GL  TG LD +T+E M  PRC
Sbjct: 52  QYLNTFYGCP---------KESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRC 102

Query: 93  GVPDVHHFREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKI 152
           G PDV ++   P  P W K+ ITYRI  YTPD++ E VD A  +AFQVWS+VTPL+FS+I
Sbjct: 103 GNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRI 162

Query: 153 NTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSG 208
           + G ADI++ F R  HGD + FDGK G+LAHAF PG+G+GGD+HFD+DE WT   G
Sbjct: 163 HDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEG 218


>gi|73808266 matrix metalloproteinase 26 preproprotein [Homo
           sapiens]
          Length = 261

 Score =  191 bits (485), Expect = 1e-48
 Identities = 108/233 (46%), Positives = 132/233 (56%), Gaps = 9/233 (3%)

Query: 32  FGERYLEKFYGLEINKLPVTKMKYSGNLMKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPR 91
           F E Y  +F+        +TK K S  L +E   ++        T  LD     ++H P 
Sbjct: 31  FVEGYFHQFF--------LTK-KESPLLTQETQTQLLQQFHRNGTDLLDMQMHALLHQPH 81

Query: 92  CGVPDVHHFREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSK 151
           CGVPD       PG   W KH +TYRI NY  DM    V  +I  A  +WSNVTPL F +
Sbjct: 82  CGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQ 141

Query: 152 INTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTN 211
           +  G ADI V F + AH D   FDG GGIL HAF P SG  G  HFD++E W+    G N
Sbjct: 142 VQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFLPNSGNPGVVHFDKNEHWSASDTGYN 201

Query: 212 LFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYGD 264
           LFL A HEIGHSLGL HS +  ++M+PTY Y D  TF+LSADDI+ IQ LYG+
Sbjct: 202 LFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDIQRIQHLYGE 254


>gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein
           [Homo sapiens]
          Length = 520

 Score =  190 bits (483), Expect = 2e-48
 Identities = 151/490 (30%), Positives = 223/490 (45%), Gaps = 69/490 (14%)

Query: 34  ERYLEKFYGL--EINKLPVTKMKYSGNLMKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPR 91
           E +LEK+  L  ++ K P T  ++S     + I+  Q    L V+G LD +TL  M  PR
Sbjct: 37  EAFLEKYGYLNEQVPKAP-TSTRFS-----DAIRAFQWVSQLPVSGVLDRATLRQMTRPR 90

Query: 92  CGVPDVHHF----------------------REMPGGPVWRKHYITYRINNYTPDMNRED 129
           CGV D + +                      R    G  W K +++YR+ N+   +    
Sbjct: 91  CGVTDTNSYAAWAERISDLFARHRTKMRRKKRFAKQGNKWYKQHLSYRLVNWPEHLPEPA 150

Query: 130 VDYAIRKAFQVWSNVTPLKFSKIN-TGMADILVVFARGAHGDF--HAFDGKGGILAHAFG 186
           V  A+R AFQ+WSNV+ L+F +   TG ADI + F +G H D   +AFDG GG LAHAF 
Sbjct: 151 VRGAVRAAFQLWSNVSALEFWEAPATGPADIRLTFFQGDHNDGLGNAFDGPGGALAHAFL 210

Query: 187 PGSGIGGDAHFDEDEFWT-THSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDI 245
           P  G   +AHFD+DE W+ +   G NLF+   HEIGH+LGL HS  P+A+M P YK +  
Sbjct: 211 PRRG---EAHFDQDERWSLSRRRGRNLFVVLAHEIGHTLGLTHSPAPRALMAPYYKRLGR 267

Query: 246 NTFRLSADDIRGIQSLYGDPKENQ---RLP------------------NPDNSEPALCDP 284
           +   LS DD+  +QSLYG P       +LP                   P+   P  C  
Sbjct: 268 DAL-LSWDDVLAVQSLYGKPLGGSVAVQLPGKLFTDFETWDSYSPQGRRPETQGPKYC-- 324

Query: 285 NLSFDAVTT-VGNKIFFFKDRFFWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQ 343
           + SFDA+T     +++ FK   FW   ++   +    +   W  LP  IEAA        
Sbjct: 325 HSSFDAITVDRQQQLYIFKGSHFWEVAADGNVSEPRPLQERWVGLPPNIEAAAVSLNDGD 384

Query: 344 VFLFKDDKYWLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRY 403
            + FK  + W     +P    P+   + G P   +  DAA+F P   R   F   +Y+  
Sbjct: 385 FYFFKGGRCWRFRGPKPVWGLPQLCRAGGLP---RHPDAALFFPPLRRLILFKGARYYVL 441

Query: 404 DERRQMMDPGYPKLITKNFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRIT---K 460
                 ++P YP+ + +++ GI  ++       +    FF+    +  D    + T   +
Sbjct: 442 ARGGLQVEPYYPRSL-QDWGGIPEEVSGALPRPDGSIIFFRDDRYWRLDQAKLQATTSGR 500

Query: 461 TLKSNSWFGC 470
                 W GC
Sbjct: 501 WATELPWMGC 510


>gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]
          Length = 707

 Score =  153 bits (386), Expect = 4e-37
 Identities = 76/175 (43%), Positives = 104/175 (59%)

Query: 34  ERYLEKFYGLEINKLPVTKMKYSGNLMKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCG 93
           +R L + Y        V +M+     +   +  +Q  L L  TG+LD++TL+ M  PRCG
Sbjct: 41  DRQLAEEYLYRYGYTRVAEMRGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCG 100

Query: 94  VPDVHHFREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKIN 153
           VPD+  F+   G   W  H ITY I NY+ D+ R  +D A  +AF +WS VTPL F+++ 
Sbjct: 101 VPDLGRFQTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVY 160

Query: 154 TGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSG 208
           +  ADI++ F    HGD + FDGK G+LAHAF PG GI GDAHFD+DE W+   G
Sbjct: 161 SRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKG 215



 Score =  105 bits (263), Expect = 7e-23
 Identities = 80/305 (26%), Positives = 131/305 (42%), Gaps = 66/305 (21%)

Query: 195 AHFDEDEFWT-THSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSAD 253
           ++FD D+ W      G +LFL A HE GH+LGL HSS P+A+M+P Y++ +     L  D
Sbjct: 377 SNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPP--LHKD 434

Query: 254 DIRGIQSLYGD-PKENQRLPNPDNSEPA-------------------------------- 280
           D+ GI+ LYG  P+   R P     +P                                 
Sbjct: 435 DVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPTGPPSAGPT 494

Query: 281 --------------------LCDPNLSFDAVTTVGNKIFFFKDRFFWLKVSE----RPKT 316
                                C+ N+ FDA+  +GN+++ FKD  +W + SE    RP+ 
Sbjct: 495 GPPTAGPSTATTVPLSPVDDACNVNI-FDAIAEIGNQLYLFKDGKYW-RFSEGRGSRPQG 552

Query: 317 SVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRPEPNYPKSIHSFGFPNF 376
              LI+  WP LP  +++ +E     ++F F   + W+ +        P+ +   G    
Sbjct: 553 PF-LIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTG--ASVLGPRRLDKLGLGAD 609

Query: 377 VKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGIGPKIDAVFYSK 436
           V ++  A+ + R  +   F   + WR+D + QM+DP     + + F G+      VF  +
Sbjct: 610 VAQVTGALRSGR-GKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDVFQYR 668

Query: 437 NKYYY 441
            K Y+
Sbjct: 669 EKAYF 673


>gi|22218341 matrix metalloproteinase 21 preproprotein [Homo
           sapiens]
          Length = 569

 Score =  142 bits (359), Expect = 5e-34
 Identities = 130/456 (28%), Positives = 203/456 (44%), Gaps = 79/456 (17%)

Query: 57  GNLMKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVH-----------------H 99
           G  + E ++  Q    L  +G+LD +TL  M+ PRCGVPD+                   
Sbjct: 82  GAALAEAVRRFQRANALPASGELDAATLAAMNRPRCGVPDMRPPPPSAPPSPPGPPPRAR 141

Query: 100 FREMPGGPV------WR--------------KHYITYRI--NNYTPDMNREDVDYAIRKA 137
            R  P  P+      W+              K  +++R+     +  ++  D    +  A
Sbjct: 142 SRRSPRAPLSLSRRGWQPRGYPDGGAAQAFSKRTLSWRLLGEALSSQLSVADQRRIVALA 201

Query: 138 FQVWSNVTPLKFSK---INTGMADILVVFARGAH-GDFHAFDGKGGILAHAFGPGSGIGG 193
           F++WS VTPL F +         DI + F RG H G   AFDG G   AHA+  G     
Sbjct: 202 FRMWSEVTPLDFREDLAAPGAAVDIKLGFGRGRHLGCPRAFDGSGQEFAHAWRLG----- 256

Query: 194 DAHFDEDEFWT--THSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLS 251
           D HFD+DE +T  T   G +L   AVHEIGH LGL H+    ++M P Y   +   F L 
Sbjct: 257 DIHFDDDEHFTPPTSDTGISLLKVAVHEIGHVLGLPHTYRTGSIMQPNYIPQE-PAFELD 315

Query: 252 ADDIRGIQSLYGDPKENQRLPNPDNSEPALCDPNLSFDAVTTVGNKIFFFKDRFFWLKVS 311
             D + IQ LYG  + +      D +   +      +  V  V    +FF++ ++WL  +
Sbjct: 316 WSDRKAIQKLYGSCEGSF-----DTAFDWIRKERNQYGEVM-VRFSTYFFRNSWYWLYEN 369

Query: 312 ERPKTSVN---LISSLWPTLPS-GIEAAYEIEA--RNQVFLFKDDKYWLISNLRPEP--- 362
              +T       I + WP +P+  I+A   I    R++ + F+ ++YW   + + +    
Sbjct: 370 RNNRTRYGDPIQILTGWPGIPTHNIDAFVHIWTWKRDERYFFQGNQYWRYDSDKDQALTE 429

Query: 363 -----NYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKL 417
                +YPK I S GFP     +D A ++ R    YFF ++  + +D  R  +   YPK 
Sbjct: 430 DEQGKSYPKLI-SEGFPGIPSPLDTAFYDRRQKLIYFFKESLVFAFDVNRNRVLNSYPKR 488

Query: 418 ITKNFQGIGPK------IDAVFYS-KNKYYYFFQGS 446
           IT+ F  + P+      ID+ +YS      +FF+G+
Sbjct: 489 ITEVFPAVIPQNHPFRNIDSAYYSYAYNSIFFFKGN 524



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 4/67 (5%)

Query: 390 YRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGIGP-KIDA---VFYSKNKYYYFFQG 445
           + TYFF ++ YW Y+ R      G P  I   + GI    IDA   ++  K    YFFQG
Sbjct: 354 FSTYFFRNSWYWLYENRNNRTRYGDPIQILTGWPGIPTHNIDAFVHIWTWKRDERYFFQG 413

Query: 446 SNQFEYD 452
           +  + YD
Sbjct: 414 NQYWRYD 420


>gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens]
          Length = 358

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 46/108 (42%), Positives = 60/108 (55%), Gaps = 8/108 (7%)

Query: 101 REMPGGPVWRK-----HYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTG 155
           R+    PV  K     ++   +  NY P++ +EDVD A  KAF++WSN + L F++    
Sbjct: 164 RQRDSSPVLEKLKQMQNFFGLKDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFES 223

Query: 156 MADILV--VFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDE 201
             DI++  VF    H D   F G  G LAHAF PG GIGGD HFD DE
Sbjct: 224 EGDIILSFVFLADLH-DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDE 270



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 37/83 (44%), Positives = 53/83 (63%), Gaps = 2/83 (2%)

Query: 347 FKDDKYWLISNLRPEPNYPKSIHS-FGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDE 405
           F+  K+W++   +    YP+ ++S F FP  VKKIDAA++     +T+FFV N+YWRYDE
Sbjct: 276 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 335

Query: 406 RRQMMDPGYPKLITKNFQGIGPK 428
             Q +D GYPK+I  +  GI  K
Sbjct: 336 NMQSVDAGYPKII-DDLPGISKK 357


>gi|5902004 matrix metalloproteinase 23B precursor [Homo sapiens]
          Length = 390

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 58/173 (33%), Positives = 90/173 (52%), Gaps = 24/173 (13%)

Query: 109 WRKHYITYRINNYTPDM-NREDVDYAIRKAFQVWSNVTPLKFSKINTGM-ADILVVFARG 166
           W    +TYRI ++  ++ +  +   A+  AF++WS+V+P  F ++     +D+ + F   
Sbjct: 88  WDHFNLTYRILSFPRNLLSPRETRRALAAAFRMWSDVSPFSFREVAPEQPSDLRIGFYPI 147

Query: 167 AHGD------FHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFW----TTHSGGTNLFLT- 215
            H D       H FDG  G LAHAF P  G     HFD+ E+W    T +S    ++LT 
Sbjct: 148 NHTDCLVSALHHCFDGPTGELAHAFFPPHG---GIHFDDSEYWVLGPTRYSWKKGVWLTD 204

Query: 216 ----AVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFR-LSADDIRGIQSLYG 263
               A HEIGH+LGL HS   +A+M   +    +  ++ LS D++ G+  LYG
Sbjct: 205 LVHVAAHEIGHALGLMHSQHGRALM---HLNATLRGWKALSQDELWGLHRLYG 254


>gi|169203660 PREDICTED: similar to hCG2042634 [Homo sapiens]
          Length = 198

 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 44/95 (46%), Positives = 54/95 (56%), Gaps = 3/95 (3%)

Query: 109 WRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILV--VFARG 166
           WR         NY P++ +EDVD A  KAF++WSN + L F++      DI++  VF   
Sbjct: 17  WRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLAD 76

Query: 167 AHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDE 201
            H D   F G  G LAHAF PG GIGGD HFD DE
Sbjct: 77  LH-DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDE 110



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 37/83 (44%), Positives = 53/83 (63%), Gaps = 2/83 (2%)

Query: 347 FKDDKYWLISNLRPEPNYPKSIHS-FGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDE 405
           F+  K+W++   +    YP+ ++S F FP  VKKIDAA++     +T+FFV N+YWRYDE
Sbjct: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 175

Query: 406 RRQMMDPGYPKLITKNFQGIGPK 428
             Q +D GYPK+I  +  GI  K
Sbjct: 176 NMQSVDAGYPKII-DDLPGISKK 197


>gi|169202084 PREDICTED: similar to hCG2042634 [Homo sapiens]
          Length = 198

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 37/83 (44%), Positives = 53/83 (63%), Gaps = 2/83 (2%)

Query: 347 FKDDKYWLISNLRPEPNYPKSIHS-FGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDE 405
           F+  K+W++   +    YP+ ++S F FP  VKKIDAA++     +T+FFV N+YWRYDE
Sbjct: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 175

Query: 406 RRQMMDPGYPKLITKNFQGIGPK 428
             Q +D GYPK+I  +  GI  K
Sbjct: 176 NMQSVDAGYPKII-DDLPGISKK 197



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 43/95 (45%), Positives = 53/95 (55%), Gaps = 3/95 (3%)

Query: 109 WRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILV--VFARG 166
           WR         NY P++ +EDVD A  KAF++WS  + L F++      DI++  VF   
Sbjct: 17  WRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFVFLAD 76

Query: 167 AHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDE 201
            H D   F G  G LAHAF PG GIGGD HFD DE
Sbjct: 77  LH-DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDE 110


>gi|239750339 PREDICTED: hypothetical protein XP_002347374 [Homo
           sapiens]
          Length = 183

 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 44/120 (36%), Positives = 64/120 (53%), Gaps = 3/120 (2%)

Query: 62  EKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPV--WRKHYITYRIN 119
           E ++  Q    L V+GQLD +T   M  PRCG+ D  + + +    +  WRK ++T+RI 
Sbjct: 55  EALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRIL 114

Query: 120 NYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVF-ARGAHGDFHAFDGKG 178
           N    +       A+R+AFQ WSNV PL F ++  G ADI + F  R +    + FDG G
Sbjct: 115 NLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPG 174


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.140    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,004,803
Number of Sequences: 37866
Number of extensions: 890376
Number of successful extensions: 1967
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1684
Number of HSP's gapped (non-prelim): 88
length of query: 470
length of database: 18,247,518
effective HSP length: 106
effective length of query: 364
effective length of database: 14,233,722
effective search space: 5181074808
effective search space used: 5181074808
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.