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Search of human proteins with 70608174
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|70608174 tumor protein D52 isoform 2 [Homo sapiens]
(207 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|70608174 tumor protein D52 isoform 2 [Homo sapiens] 395 e-110
gi|4827038 tumor protein D52 isoform 3 [Homo sapiens] 338 2e-93
gi|70608172 tumor protein D52 isoform 1 [Homo sapiens] 326 1e-89
gi|4507641 tumor protein D52-like 1 isoform 1 [Homo sapiens] 216 1e-56
gi|40805866 tumor protein D52-like 2 isoform b [Homo sapiens] 202 2e-52
gi|51173744 tumor protein D52-like 1 isoform 2 [Homo sapiens] 198 2e-51
gi|40805864 tumor protein D52-like 2 isoform a [Homo sapiens] 190 6e-49
gi|40805870 tumor protein D52-like 2 isoform d [Homo sapiens] 184 6e-47
gi|40805868 tumor protein D52-like 2 isoform c [Homo sapiens] 172 2e-43
gi|40805862 tumor protein D52-like 2 isoform f [Homo sapiens] 160 5e-40
gi|51173746 tumor protein D52-like 1 isoform 3 [Homo sapiens] 159 1e-39
gi|40805860 tumor protein D52-like 2 isoform e [Homo sapiens] 149 2e-36
gi|51173748 tumor protein D52-like 1 isoform 4 [Homo sapiens] 147 6e-36
gi|49574214 protein kinase NYD-SP25 isoform 1 [Homo sapiens] 95 4e-20
gi|49574216 protein kinase NYD-SP25 isoform 3 [Homo sapiens] 92 4e-19
gi|49574212 protein kinase NYD-SP25 isoform 2 [Homo sapiens] 92 4e-19
gi|116517292 cut-like 2 [Homo sapiens] 40 0.002
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 39 0.003
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 37 0.009
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 37 0.009
gi|81295809 pericentrin [Homo sapiens] 37 0.009
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 36 0.020
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 36 0.020
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 36 0.026
gi|157837985 kazrin isoform E [Homo sapiens] 36 0.026
gi|65301128 kazrin isoform C [Homo sapiens] 36 0.026
gi|65301130 kazrin isoform B [Homo sapiens] 36 0.026
gi|63999741 kazrin isoform C [Homo sapiens] 36 0.026
gi|63147424 kazrin isoform A [Homo sapiens] 36 0.026
gi|110815815 centlein isoform 1 [Homo sapiens] 36 0.026
>gi|70608174 tumor protein D52 isoform 2 [Homo sapiens]
Length = 207
Score = 395 bits (1014), Expect = e-110
Identities = 207/207 (100%), Positives = 207/207 (100%)
Query: 1 MDRGEQGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAK 60
MDRGEQGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAK
Sbjct: 1 MDRGEQGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAK 60
Query: 61 EKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSV 120
EKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSV
Sbjct: 61 EKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSV 120
Query: 121 ITKKLEDVKLQAFSHSFSIRSIQHSISMPAMRNSPTFKSFEEKVENLKSKVGGTKPAGGD 180
ITKKLEDVKLQAFSHSFSIRSIQHSISMPAMRNSPTFKSFEEKVENLKSKVGGTKPAGGD
Sbjct: 121 ITKKLEDVKLQAFSHSFSIRSIQHSISMPAMRNSPTFKSFEEKVENLKSKVGGTKPAGGD 180
Query: 181 FGEVLNSAANASATTTEPLPEKTQESL 207
FGEVLNSAANASATTTEPLPEKTQESL
Sbjct: 181 FGEVLNSAANASATTTEPLPEKTQESL 207
>gi|4827038 tumor protein D52 isoform 3 [Homo sapiens]
Length = 184
Score = 338 bits (867), Expect = 2e-93
Identities = 184/207 (88%), Positives = 184/207 (88%), Gaps = 23/207 (11%)
Query: 1 MDRGEQGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAK 60
MDRGEQGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAK
Sbjct: 1 MDRGEQGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAK 60
Query: 61 EKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSV 120
EKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSV
Sbjct: 61 EKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSV 120
Query: 121 ITKKLEDVKLQAFSHSFSIRSIQHSISMPAMRNSPTFKSFEEKVENLKSKVGGTKPAGGD 180
ITKKLEDVK NSPTFKSFEEKVENLKSKVGGTKPAGGD
Sbjct: 121 ITKKLEDVK-----------------------NSPTFKSFEEKVENLKSKVGGTKPAGGD 157
Query: 181 FGEVLNSAANASATTTEPLPEKTQESL 207
FGEVLNSAANASATTTEPLPEKTQESL
Sbjct: 158 FGEVLNSAANASATTTEPLPEKTQESL 184
>gi|70608172 tumor protein D52 isoform 1 [Homo sapiens]
Length = 224
Score = 326 bits (835), Expect = 1e-89
Identities = 178/201 (88%), Positives = 178/201 (88%), Gaps = 23/201 (11%)
Query: 7 GLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAE 66
GLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAE
Sbjct: 47 GLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAE 106
Query: 67 IKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLE 126
IKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLE
Sbjct: 107 IKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLE 166
Query: 127 DVKLQAFSHSFSIRSIQHSISMPAMRNSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLN 186
DVK NSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLN
Sbjct: 167 DVK-----------------------NSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLN 203
Query: 187 SAANASATTTEPLPEKTQESL 207
SAANASATTTEPLPEKTQESL
Sbjct: 204 SAANASATTTEPLPEKTQESL 224
>gi|4507641 tumor protein D52-like 1 isoform 1 [Homo sapiens]
Length = 204
Score = 216 bits (549), Expect = 1e-56
Identities = 119/209 (56%), Positives = 151/209 (72%), Gaps = 14/209 (6%)
Query: 1 MDRGEQGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAK 60
M+ QGLL T+P+ ED A+ + LSEEE+EEL+ EL ++E+EI TL QVL+AK
Sbjct: 1 MEAQAQGLLETEPLQGTDEDAVASADFSSMLSEEEKEELKAELVQLEDEITTLRQVLSAK 60
Query: 61 EKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSV 120
E+HL EIK+KLG+N + ELKQN +K W D+ T+AYKKT ETLS AGQKA+AAFS+VG+
Sbjct: 61 ERHLVEIKQKLGMNLMNELKQNFSKSWHDMQTTTAYKKTHETLSHAGQKATAAFSNVGTA 120
Query: 121 ITKKLEDVKLQAFSHSFSIRSIQHSISMPAMRNSPTFKSFEEKVE----NLKSKVGGTKP 176
I+KK D+ S+SIR HSISMPAMRNSPTFKSFEE+VE +LK+KVGGT P
Sbjct: 121 ISKKFGDM-------SYSIR---HSISMPAMRNSPTFKSFEERVETTVTSLKTKVGGTNP 170
Query: 177 AGGDFGEVLNSAANASATTTEPLPEKTQE 205
GG F EVL+S A+ASA + +T+E
Sbjct: 171 NGGSFEEVLSSTAHASAQSLAGGSRRTKE 199
>gi|40805866 tumor protein D52-like 2 isoform b [Homo sapiens]
Length = 209
Score = 202 bits (514), Expect = 2e-52
Identities = 107/180 (59%), Positives = 134/180 (74%), Gaps = 2/180 (1%)
Query: 21 VAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELK 80
VAA A E L+E E+EELR EL KVEEEI TL QVLAAKE+H E+KR+LG+++L ELK
Sbjct: 31 VAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLAAKERHCGELKRRLGLSTLGELK 90
Query: 81 QNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKLQAFSHSFSIR 140
QN+++ W DV +SAYKKT ETLSQAGQK SAA S+VGS I++KL D++ FSHSFS
Sbjct: 91 QNLSRSWHDVQVSSAYKKTQETLSQAGQKTSAALSTVGSAISRKLGDMRAHPFSHSFSSY 150
Query: 141 SIQHSISMPAMRNSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLNSAANASATTTEPLP 200
SI+HSISMPAMRNS TFKSFE++V +KSKV G + G D + +SA + ++P P
Sbjct: 151 SIRHSISMPAMRNSATFKSFEDRVGTIKSKVVGDRENGSD--NLPSSAGSGDKPLSDPAP 208
>gi|51173744 tumor protein D52-like 1 isoform 2 [Homo sapiens]
Length = 175
Score = 198 bits (504), Expect = 2e-51
Identities = 109/179 (60%), Positives = 136/179 (75%), Gaps = 14/179 (7%)
Query: 31 LSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAKGWQDV 90
LSEEE+EEL+ EL ++E+EI TL QVL+AKE+HL EIK+KLG+N + ELKQN +K W D+
Sbjct: 2 LSEEEKEELKAELVQLEDEITTLRQVLSAKERHLVEIKQKLGMNLMNELKQNFSKSWHDM 61
Query: 91 TATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKLQAFSHSFSIRSIQHSISMPA 150
T+AYKKT ETLS AGQKA+AAFS+VG+ I+KK D+ S+SIR HSISMPA
Sbjct: 62 QTTTAYKKTHETLSHAGQKATAAFSNVGTAISKKFGDM-------SYSIR---HSISMPA 111
Query: 151 MRNSPTFKSFEEKVE----NLKSKVGGTKPAGGDFGEVLNSAANASATTTEPLPEKTQE 205
MRNSPTFKSFEE+VE +LK+KVGGT P GG F EVL+S A+ASA + +T+E
Sbjct: 112 MRNSPTFKSFEERVETTVTSLKTKVGGTNPNGGSFEEVLSSTAHASAQSLAGGSRRTKE 170
>gi|40805864 tumor protein D52-like 2 isoform a [Homo sapiens]
Length = 229
Score = 190 bits (483), Expect = 6e-49
Identities = 107/200 (53%), Positives = 134/200 (67%), Gaps = 22/200 (11%)
Query: 21 VAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELK 80
VAA A E L+E E+EELR EL KVEEEI TL QVLAAKE+H E+KR+LG+++L ELK
Sbjct: 31 VAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLAAKERHCGELKRRLGLSTLGELK 90
Query: 81 QNIAKGWQDVTATSAY--------------------KKTSETLSQAGQKASAAFSSVGSV 120
QN+++ W DV +SAY KKT ETLSQAGQK SAA S+VGS
Sbjct: 91 QNLSRSWHDVQVSSAYVKTSEKLGEWNEKVTQSDLYKKTQETLSQAGQKTSAALSTVGSA 150
Query: 121 ITKKLEDVKLQAFSHSFSIRSIQHSISMPAMRNSPTFKSFEEKVENLKSKVGGTKPAGGD 180
I++KL D++ FSHSFS SI+HSISMPAMRNS TFKSFE++V +KSKV G + G D
Sbjct: 151 ISRKLGDMRAHPFSHSFSSYSIRHSISMPAMRNSATFKSFEDRVGTIKSKVVGDRENGSD 210
Query: 181 FGEVLNSAANASATTTEPLP 200
+ +SA + ++P P
Sbjct: 211 --NLPSSAGSGDKPLSDPAP 228
>gi|40805870 tumor protein D52-like 2 isoform d [Homo sapiens]
Length = 200
Score = 184 bits (466), Expect = 6e-47
Identities = 102/180 (56%), Positives = 128/180 (71%), Gaps = 11/180 (6%)
Query: 21 VAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELK 80
VAA A E L+E E+EELR EL KVEEEI TL QVLAAKE+H E+KR+LG+++L ELK
Sbjct: 31 VAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLAAKERHCGELKRRLGLSTLGELK 90
Query: 81 QNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKLQAFSHSFSIR 140
QN+++ W DV +SAYKKT ETLSQAGQK SAA S+VGS I++KL D+ S
Sbjct: 91 QNLSRSWHDVQVSSAYKKTQETLSQAGQKTSAALSTVGSAISRKLGDM---------SSY 141
Query: 141 SIQHSISMPAMRNSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLNSAANASATTTEPLP 200
SI+HSISMPAMRNS TFKSFE++V +KSKV G + G D + +SA + ++P P
Sbjct: 142 SIRHSISMPAMRNSATFKSFEDRVGTIKSKVVGDRENGSD--NLPSSAGSGDKPLSDPAP 199
>gi|40805868 tumor protein D52-like 2 isoform c [Homo sapiens]
Length = 220
Score = 172 bits (435), Expect = 2e-43
Identities = 102/200 (51%), Positives = 128/200 (64%), Gaps = 31/200 (15%)
Query: 21 VAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELK 80
VAA A E L+E E+EELR EL KVEEEI TL QVLAAKE+H E+KR+LG+++L ELK
Sbjct: 31 VAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLAAKERHCGELKRRLGLSTLGELK 90
Query: 81 QNIAKGWQDVTATSA--------------------YKKTSETLSQAGQKASAAFSSVGSV 120
QN+++ W DV +SA YKKT ETLSQAGQK SAA S+VGS
Sbjct: 91 QNLSRSWHDVQVSSAYVKTSEKLGEWNEKVTQSDLYKKTQETLSQAGQKTSAALSTVGSA 150
Query: 121 ITKKLEDVKLQAFSHSFSIRSIQHSISMPAMRNSPTFKSFEEKVENLKSKVGGTKPAGGD 180
I++KL D+ S SI+HSISMPAMRNS TFKSFE++V +KSKV G + G D
Sbjct: 151 ISRKLGDM---------SSYSIRHSISMPAMRNSATFKSFEDRVGTIKSKVVGDRENGSD 201
Query: 181 FGEVLNSAANASATTTEPLP 200
+ +SA + ++P P
Sbjct: 202 --NLPSSAGSGDKPLSDPAP 219
>gi|40805862 tumor protein D52-like 2 isoform f [Homo sapiens]
Length = 186
Score = 160 bits (406), Expect = 5e-40
Identities = 92/180 (51%), Positives = 116/180 (64%), Gaps = 25/180 (13%)
Query: 21 VAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELK 80
VAA A E L+E E+EELR EL KVEEEI TL QVLAAKE+H E+KR+LG+++L ELK
Sbjct: 31 VAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLAAKERHCGELKRRLGLSTLGELK 90
Query: 81 QNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKLQAFSHSFSIR 140
QN+++ W DV +SAYKKT ETLSQAGQK SAA S+VGS I++KL D
Sbjct: 91 QNLSRSWHDVQVSSAYKKTQETLSQAGQKTSAALSTVGSAISRKLGD------------- 137
Query: 141 SIQHSISMPAMRNSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLNSAANASATTTEPLP 200
MRNS TFKSFE++V +KSKV G + G D + +SA + ++P P
Sbjct: 138 ----------MRNSATFKSFEDRVGTIKSKVVGDRENGSD--NLPSSAGSGDKPLSDPAP 185
>gi|51173746 tumor protein D52-like 1 isoform 3 [Homo sapiens]
Length = 144
Score = 159 bits (403), Expect = 1e-39
Identities = 86/152 (56%), Positives = 110/152 (72%), Gaps = 10/152 (6%)
Query: 1 MDRGEQGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAK 60
M+ QGLL T+P+ ED A+ + LSEEE+EEL+ EL ++E+EI TL QVL+AK
Sbjct: 1 MEAQAQGLLETEPLQGTDEDAVASADFSSMLSEEEKEELKAELVQLEDEITTLRQVLSAK 60
Query: 61 EKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSV 120
E+HL EIK+KLG+N + ELKQN +K W D+ T+AYKKT ETLS AGQKA+AAFS+VG+
Sbjct: 61 ERHLVEIKQKLGMNLMNELKQNFSKSWHDMQTTTAYKKTHETLSHAGQKATAAFSNVGTA 120
Query: 121 ITKKLEDVKLQAFSHSFSIRSIQHSISMPAMR 152
I+KK D+ S+SIR HSISMPAMR
Sbjct: 121 ISKKFGDM-------SYSIR---HSISMPAMR 142
>gi|40805860 tumor protein D52-like 2 isoform e [Homo sapiens]
Length = 206
Score = 149 bits (375), Expect = 2e-36
Identities = 92/200 (46%), Positives = 116/200 (58%), Gaps = 45/200 (22%)
Query: 21 VAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELK 80
VAA A E L+E E+EELR EL KVEEEI TL QVLAAKE+H E+KR+LG+++L ELK
Sbjct: 31 VAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLAAKERHCGELKRRLGLSTLGELK 90
Query: 81 QNIAKGWQDVTATSA--------------------YKKTSETLSQAGQKASAAFSSVGSV 120
QN+++ W DV +SA YKKT ETLSQAGQK SAA S+VGS
Sbjct: 91 QNLSRSWHDVQVSSAYVKTSEKLGEWNEKVTQSDLYKKTQETLSQAGQKTSAALSTVGSA 150
Query: 121 ITKKLEDVKLQAFSHSFSIRSIQHSISMPAMRNSPTFKSFEEKVENLKSKVGGTKPAGGD 180
I++KL D MRNS TFKSFE++V +KSKV G + G D
Sbjct: 151 ISRKLGD-----------------------MRNSATFKSFEDRVGTIKSKVVGDRENGSD 187
Query: 181 FGEVLNSAANASATTTEPLP 200
+ +SA + ++P P
Sbjct: 188 --NLPSSAGSGDKPLSDPAP 205
>gi|51173748 tumor protein D52-like 1 isoform 4 [Homo sapiens]
Length = 131
Score = 147 bits (371), Expect = 6e-36
Identities = 73/129 (56%), Positives = 97/129 (75%)
Query: 1 MDRGEQGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAK 60
M+ QGLL T+P+ ED A+ + LSEEE+EEL+ EL ++E+EI TL QVL+AK
Sbjct: 1 MEAQAQGLLETEPLQGTDEDAVASADFSSMLSEEEKEELKAELVQLEDEITTLRQVLSAK 60
Query: 61 EKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSV 120
E+HL EIK+KLG+N + ELKQN +K W D+ T+AYKKT ETLS AGQKA+AAFS+VG+
Sbjct: 61 ERHLVEIKQKLGMNLMNELKQNFSKSWHDMQTTTAYKKTHETLSHAGQKATAAFSNVGTA 120
Query: 121 ITKKLEDVK 129
I+KK D++
Sbjct: 121 ISKKFGDMR 129
>gi|49574214 protein kinase NYD-SP25 isoform 1 [Homo sapiens]
Length = 140
Score = 95.1 bits (235), Expect = 4e-20
Identities = 61/152 (40%), Positives = 82/152 (53%), Gaps = 32/152 (21%)
Query: 26 SATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAK 85
S E L+E EQ EL+ +L K+E EI TL VLAAKE+ E+KRKLG+ +L L+QN++K
Sbjct: 19 SELEDLTEPEQRELKTKLTKLEAEIVTLRHVLAAKERRCGELKRKLGLTALVGLRQNLSK 78
Query: 86 GWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKLQAFSHSFSIRSIQHS 145
W DV ++ Y K QK SAA S++G++I +KL VK
Sbjct: 79 SWLDVQVSNTYVK---------QKTSAALSTMGTLICRKLGGVK---------------- 113
Query: 146 ISMPAMRNSPTFKSFEEKVENLKSKVGGTKPA 177
S T +SFE + +KSKV G K A
Sbjct: 114 -------KSATLRSFEGLMGTIKSKVSGGKRA 138
>gi|49574216 protein kinase NYD-SP25 isoform 3 [Homo sapiens]
Length = 132
Score = 91.7 bits (226), Expect = 4e-19
Identities = 52/112 (46%), Positives = 70/112 (62%), Gaps = 9/112 (8%)
Query: 26 SATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAK 85
S E L+E EQ EL+ +L K+E EI TL VLAAKE+ E+KRKLG+ +L L+QN++K
Sbjct: 19 SELEDLTEPEQRELKTKLTKLEAEIVTLRHVLAAKERRCGELKRKLGLTALVGLRQNLSK 78
Query: 86 GWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKLQAFSHSF 137
W DV ++ Y K QK SAA S++G++I +KL VK A SF
Sbjct: 79 SWLDVQVSNTYVK---------QKTSAALSTMGTLICRKLGGVKKSATLRSF 121
>gi|49574212 protein kinase NYD-SP25 isoform 2 [Homo sapiens]
Length = 136
Score = 91.7 bits (226), Expect = 4e-19
Identities = 52/112 (46%), Positives = 70/112 (62%), Gaps = 9/112 (8%)
Query: 26 SATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAK 85
S E L+E EQ EL+ +L K+E EI TL VLAAKE+ E+KRKLG+ +L L+QN++K
Sbjct: 19 SELEDLTEPEQRELKTKLTKLEAEIVTLRHVLAAKERRCGELKRKLGLTALVGLRQNLSK 78
Query: 86 GWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKLQAFSHSF 137
W DV ++ Y K QK SAA S++G++I +KL VK A SF
Sbjct: 79 SWLDVQVSNTYVK---------QKTSAALSTMGTLICRKLGGVKKSATLRSF 121
>gi|116517292 cut-like 2 [Homo sapiens]
Length = 1486
Score = 39.7 bits (91), Expect = 0.002
Identities = 35/142 (24%), Positives = 60/142 (42%), Gaps = 8/142 (5%)
Query: 39 LRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKK 98
L++EL V E+ + KHL E++R+ N +E+++ +A +++
Sbjct: 20 LQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEIREMVA------PVLKSFQA 73
Query: 99 TSETLSQAGQKASAAFSSVGSVITKKLEDVKLQAFSHSFSIRSIQHSISMPAMRNSPTFK 158
LS+ Q+A AAF SV + + + V + + S R S
Sbjct: 74 EVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPSGQPRRDLHT 133
Query: 159 SFEEKVENL--KSKVGGTKPAG 178
S++ E L K + GT PAG
Sbjct: 134 SWKRNPELLSPKEQREGTSPAG 155
Score = 28.1 bits (61), Expect = 5.5
Identities = 14/38 (36%), Positives = 21/38 (55%)
Query: 33 EEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRK 70
+E Q L L + EE+I+ L L A + L E++RK
Sbjct: 190 QEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRK 227
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 38.9 bits (89), Expect = 0.003
Identities = 24/99 (24%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
Query: 13 PVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLG 72
P P + +T S T +LS E+++ L ELA + ++ + Q L K + L + + ++
Sbjct: 226 PSPIKSSSADSTPSPTSSLSSEDKQHLAVELADTKARLRRVRQELEDKTEQLVDTRHEVD 285
Query: 73 --INSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQK 109
+ LQ++KQ + D + AY+ ++L + +
Sbjct: 286 QLVLELQKVKQENIQLAADARSARAYRDELDSLREKANR 324
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 37.4 bits (85), Expect = 0.009
Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 9/86 (10%)
Query: 5 EQGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTL-------SQVL 57
E+ L + + E E V A + T +E++ EEL + KV++E++++ Q L
Sbjct: 843 EEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSL 902
Query: 58 AAKEKHLAEIK--RKLGINSLQELKQ 81
A KE HL ++ R+ + + E+KQ
Sbjct: 903 AEKETHLTNLRAERRKHLEEVLEMKQ 928
Score = 28.1 bits (61), Expect = 5.5
Identities = 39/214 (18%), Positives = 94/214 (43%), Gaps = 36/214 (16%)
Query: 25 ISATETLSEEEQEELRRELAK-VEEEIQTLSQVLAAKEKHLAEIKRK-LGINS-LQELKQ 81
+S E E +Q E+ R +K ++ +++ L + L++KE E+K+K G+ + + ++KQ
Sbjct: 414 LSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQ 473
Query: 82 NIAKGWQDVTATSAYKKT---------------SETLSQAGQKASAAFSSVGSV------ 120
+++ ++ A +T E+L+ Q+A+ + V ++
Sbjct: 474 ELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEE 533
Query: 121 -------ITKKLEDVKLQAFSHSFSIRSIQHSISMPAMRNSPTFKSFEEKVENLKSKVGG 173
TK+++D+ + + + I ++ + + + ++K+ENL+ ++
Sbjct: 534 KETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERK----VNVLQKKIENLQEQLRD 589
Query: 174 TKPAGGDFGEVLNSAANASATTTEPLPEKTQESL 207
+ E + S A T T+ +E+L
Sbjct: 590 KEKQMSSLKERVKS-LQADTTNTDTALTTLEEAL 622
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 37.4 bits (85), Expect = 0.009
Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 9/86 (10%)
Query: 5 EQGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTL-------SQVL 57
E+ L + + E E V A + T +E++ EEL + KV++E++++ Q L
Sbjct: 815 EEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSL 874
Query: 58 AAKEKHLAEIK--RKLGINSLQELKQ 81
A KE HL ++ R+ + + E+KQ
Sbjct: 875 AEKETHLTNLRAERRKHLEEVLEMKQ 900
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 37.4 bits (85), Expect = 0.009
Identities = 39/177 (22%), Positives = 74/177 (41%), Gaps = 16/177 (9%)
Query: 32 SEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAKGWQDVT 91
S ++ E+L R L +V++E+ L +L++KE L +LQEL+ KG
Sbjct: 2616 SRQKSEQLSRSLCEVQQEVLQLRSMLSSKENELKA--------ALQELESEQGKG--RAL 2665
Query: 92 ATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKL-QAFSHSFSIR-SIQHSISMP 149
+ ++ L + Q A A S+ T++ + +L A H + + ++Q + +
Sbjct: 2666 QSQLEEEQLRHLQRESQSAKALEELRASLETQRAQSSRLCVALKHEQTAKDNLQKELRIE 2725
Query: 150 AMRNSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLNSAANASATTTEPLPEKTQES 206
R ++ L+ + K + E L TE L ++TQE+
Sbjct: 2726 HSRCEALLAQERSQLSELQKDLAAEKSRTLELSEALRH----ERLLTEQLSQRTQEA 2778
Score = 29.6 bits (65), Expect = 1.9
Identities = 37/156 (23%), Positives = 63/156 (40%), Gaps = 7/156 (4%)
Query: 19 EDVAATISATETLSEEEQEEL--RRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSL 76
+D +A +S + L E +E+L R AK E + L Q +A+ +KHL +R+
Sbjct: 1427 KDRSALLSQMKILESELEEQLSQHRGCAKQAEAVTALEQQVASLDKHLRN-QRQFMDEQA 1485
Query: 77 QELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKLQAFSHS 136
E + + Q++ + + G + S G V +L KL+
Sbjct: 1486 AEREHEREEFQQEIQRLEGQLRQAAKPQPWGPRDSQQAPLDGEV---ELLQQKLREKLDE 1542
Query: 137 FSIRSIQ-HSISMPAMRNSPTFKSFEEKVENLKSKV 171
F+ +IQ S + K EE N++ KV
Sbjct: 1543 FNELAIQKESADRQVLMQEEEIKRLEEMNINIRKKV 1578
Score = 29.3 bits (64), Expect = 2.5
Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 4/118 (3%)
Query: 16 EEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKH--LAEIKRKLGI 73
E G + A + ++ + E E LR L+ + L+Q KEK L E++ L
Sbjct: 227 ESGREDEAGLHQSQAVHGLELEALRLSLSNMHTAQLELTQANLQKEKETALTELREMLNS 286
Query: 74 NSLQELK--QNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVK 129
QEL Q+ + ++ ++ E + + GQ+A+ + S + K + VK
Sbjct: 287 RRAQELALLQSRQQHELELLREQHAREKEEVVLRCGQEAAELKEKLQSEMEKNAQIVK 344
Score = 28.9 bits (63), Expect = 3.2
Identities = 16/80 (20%), Positives = 37/80 (46%)
Query: 3 RGEQGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEK 62
+GE G + + E+ E + + + +EE+E L +L K ++Q L + +
Sbjct: 1055 QGEFGSEKKTALHEKEETLRLQSAQAQPFHQEEKESLSLQLQKKNHQVQQLKDQVLSLSH 1114
Query: 63 HLAEIKRKLGINSLQELKQN 82
+ E + +L + + ++N
Sbjct: 1115 EIEECRSELEVLQQRREREN 1134
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 36.2 bits (82), Expect = 0.020
Identities = 43/200 (21%), Positives = 84/200 (42%), Gaps = 26/200 (13%)
Query: 14 VPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKE-KHLAEIKR--- 69
+ E E I A+ EEE + E++K++ E+Q Q L E + + ++ +
Sbjct: 1159 IKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKA 1218
Query: 70 -----KLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKK 124
+ I+SL E N+ + +++V + K E +S +K FS I ++
Sbjct: 1219 TKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKE-ISAKDEKELLHFS-----IEQE 1272
Query: 125 LEDVKLQAFSHSFSIRSIQHSISMPAMRNSPTFKSFEEKVENLKSKVGGTKPAGGDFGEV 184
++D K + +I +Q I A + ++ + K+ L + V K A
Sbjct: 1273 IKDQKERCDKSLTTITELQRRIQESAKQ----IEAKDNKITELLNDVERLKQA------- 1321
Query: 185 LNSAANASATTTEPLPEKTQ 204
LN + + T+ P ++Q
Sbjct: 1322 LNGLSQLTYTSGNPTKRQSQ 1341
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 36.2 bits (82), Expect = 0.020
Identities = 43/200 (21%), Positives = 84/200 (42%), Gaps = 26/200 (13%)
Query: 14 VPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKE-KHLAEIKR--- 69
+ E E I A+ EEE + E++K++ E+Q Q L E + + ++ +
Sbjct: 1172 IKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKA 1231
Query: 70 -----KLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKK 124
+ I+SL E N+ + +++V + K E +S +K FS I ++
Sbjct: 1232 TKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKE-ISAKDEKELLHFS-----IEQE 1285
Query: 125 LEDVKLQAFSHSFSIRSIQHSISMPAMRNSPTFKSFEEKVENLKSKVGGTKPAGGDFGEV 184
++D K + +I +Q I A + ++ + K+ L + V K A
Sbjct: 1286 IKDQKERCDKSLTTITELQRRIQESAKQ----IEAKDNKITELLNDVERLKQA------- 1334
Query: 185 LNSAANASATTTEPLPEKTQ 204
LN + + T+ P ++Q
Sbjct: 1335 LNGLSQLTYTSGNPTKRQSQ 1354
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 35.8 bits (81), Expect = 0.026
Identities = 30/114 (26%), Positives = 58/114 (50%), Gaps = 5/114 (4%)
Query: 16 EEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINS 75
E+ E++ A ++A + E+E EL++++ +E TL++V KEKH E K K
Sbjct: 928 EDEEEINAELTAKKRKLEDECSELKKDIDDLE---LTLAKV--EKEKHATENKVKNLTEE 982
Query: 76 LQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVK 129
L L + IAK ++ A + + QA + + + S + +++ED++
Sbjct: 983 LSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLE 1036
Score = 28.5 bits (62), Expect = 4.2
Identities = 24/103 (23%), Positives = 51/103 (49%), Gaps = 11/103 (10%)
Query: 16 EEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAA--------KEKHLAEI 67
EE E + + +S ++ ++ EEL+R+L + + L+ L + +E++ E
Sbjct: 1293 EEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQ 1352
Query: 68 KRKLGI-NSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQK 109
+ K + +L + +A+ W+ T A ++T E L +A +K
Sbjct: 1353 EGKAELQRALSKANSEVAQ-WRTKYETDAIQRTEE-LEEAKKK 1393
>gi|157837985 kazrin isoform E [Homo sapiens]
Length = 775
Score = 35.8 bits (81), Expect = 0.026
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 16 EEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINS 75
+E ED ++ + L E E+ ELRR+ + + L L K+ + E++ +L +
Sbjct: 185 KESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAM-- 242
Query: 76 LQELKQNIAKGWQDVTATSAYKKTSETLSQAGQK 109
KQ++A +DV + ET+ Q+
Sbjct: 243 ---AKQSLATLTKDVPKRHSLAMPGETVLNGNQE 273
>gi|65301128 kazrin isoform C [Homo sapiens]
Length = 327
Score = 35.8 bits (81), Expect = 0.026
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 16 EEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINS 75
+E ED ++ + L E E+ ELRR+ + + L L K+ + E++ +L +
Sbjct: 91 KESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAM-- 148
Query: 76 LQELKQNIAKGWQDVTATSAYKKTSETLSQAGQK 109
KQ++A +DV + ET+ Q+
Sbjct: 149 ---AKQSLATLTKDVPKRHSLAMPGETVLNGNQE 179
>gi|65301130 kazrin isoform B [Homo sapiens]
Length = 415
Score = 35.8 bits (81), Expect = 0.026
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 16 EEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINS 75
+E ED ++ + L E E+ ELRR+ + + L L K+ + E++ +L +
Sbjct: 179 KESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAM-- 236
Query: 76 LQELKQNIAKGWQDVTATSAYKKTSETLSQAGQK 109
KQ++A +DV + ET+ Q+
Sbjct: 237 ---AKQSLATLTKDVPKRHSLAMPGETVLNGNQE 267
>gi|63999741 kazrin isoform C [Homo sapiens]
Length = 327
Score = 35.8 bits (81), Expect = 0.026
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 16 EEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINS 75
+E ED ++ + L E E+ ELRR+ + + L L K+ + E++ +L +
Sbjct: 91 KESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAM-- 148
Query: 76 LQELKQNIAKGWQDVTATSAYKKTSETLSQAGQK 109
KQ++A +DV + ET+ Q+
Sbjct: 149 ---AKQSLATLTKDVPKRHSLAMPGETVLNGNQE 179
>gi|63147424 kazrin isoform A [Homo sapiens]
Length = 421
Score = 35.8 bits (81), Expect = 0.026
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 16 EEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINS 75
+E ED ++ + L E E+ ELRR+ + + L L K+ + E++ +L +
Sbjct: 185 KESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAM-- 242
Query: 76 LQELKQNIAKGWQDVTATSAYKKTSETLSQAGQK 109
KQ++A +DV + ET+ Q+
Sbjct: 243 ---AKQSLATLTKDVPKRHSLAMPGETVLNGNQE 273
>gi|110815815 centlein isoform 1 [Homo sapiens]
Length = 1406
Score = 35.8 bits (81), Expect = 0.026
Identities = 25/129 (19%), Positives = 60/129 (46%), Gaps = 12/129 (9%)
Query: 42 ELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSE 101
EL K ++TL L AKE+H ++E+ + I++ +D+T + +
Sbjct: 1107 ELTKQSSNVKTLKFELLAKEEH------------IKEMHEKISRMERDITMKRHLIEDLK 1154
Query: 102 TLSQAGQKASAAFSSVGSVITKKLEDVKLQAFSHSFSIRSIQHSISMPAMRNSPTFKSFE 161
+ +++ +FS + + KK++ + + + SI S++ +++ S + ++
Sbjct: 1155 FRQKVNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEKSQYEQMYQ 1214
Query: 162 EKVENLKSK 170
+ E L+ K
Sbjct: 1215 KSKEELEKK 1223
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.120 0.309
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,970,397
Number of Sequences: 37866
Number of extensions: 288573
Number of successful extensions: 2941
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 119
Number of HSP's successfully gapped in prelim test: 260
Number of HSP's that attempted gapping in prelim test: 2301
Number of HSP's gapped (non-prelim): 903
length of query: 207
length of database: 18,247,518
effective HSP length: 98
effective length of query: 109
effective length of database: 14,536,650
effective search space: 1584494850
effective search space used: 1584494850
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.