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Search of human proteins with 7019519
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7019519 proprotein convertase subtilisin/kexin type 1
inhibitor precursor [Homo sapiens]
(260 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7019519 proprotein convertase subtilisin/kexin type 1 inhibit... 512 e-145
gi|117938759 GNAS complex locus XLas [Homo sapiens] 43 2e-04
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s... 43 2e-04
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ... 43 2e-04
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ... 43 2e-04
gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s... 43 2e-04
gi|113416879 PREDICTED: hypothetical protein [Homo sapiens] 39 0.003
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] 38 0.010
gi|83921602 solute carrier family 38, member 10 isoform a [Homo ... 37 0.017
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 37 0.017
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 37 0.023
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 37 0.023
gi|21359951 RNA binding motif protein 42 [Homo sapiens] 36 0.038
gi|116006967 neuregulin 1 isoform GGF2 [Homo sapiens] 35 0.050
gi|239755509 PREDICTED: hypothetical protein [Homo sapiens] 35 0.050
gi|239750019 PREDICTED: hypothetical protein [Homo sapiens] 35 0.050
gi|239744332 PREDICTED: hypothetical protein XP_002343119 [Homo ... 35 0.050
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 35 0.066
gi|191252785 centrobin, centrosomal BRCA2 interacting protein is... 35 0.066
gi|80861396 centrobin, centrosomal BRCA2 interacting protein iso... 35 0.066
gi|71274172 ankyrin repeat domain 56 [Homo sapiens] 35 0.066
gi|24431933 reticulon 4 isoform B [Homo sapiens] 35 0.086
gi|47519490 reticulon 4 isoform D [Homo sapiens] 35 0.086
gi|24431935 reticulon 4 isoform A [Homo sapiens] 35 0.086
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 35 0.086
gi|157364934 fibrosin [Homo sapiens] 34 0.11
gi|239756307 PREDICTED: similar to ubiquitin-associated protein ... 34 0.15
gi|169165603 PREDICTED: similar to proline rich 20 [Homo sapiens] 34 0.15
gi|239750857 PREDICTED: similar to ubiquitin-associated protein ... 34 0.15
gi|169166067 PREDICTED: similar to proline rich 20 [Homo sapiens] 34 0.15
>gi|7019519 proprotein convertase subtilisin/kexin type 1 inhibitor
precursor [Homo sapiens]
Length = 260
Score = 512 bits (1319), Expect = e-145
Identities = 260/260 (100%), Positives = 260/260 (100%)
Query: 1 MAGSPLLWGPRAGGVGLLVLLLLGLFRPPPALCARPVKEPRGLSAASPPLAETGAPRRFR 60
MAGSPLLWGPRAGGVGLLVLLLLGLFRPPPALCARPVKEPRGLSAASPPLAETGAPRRFR
Sbjct: 1 MAGSPLLWGPRAGGVGLLVLLLLGLFRPPPALCARPVKEPRGLSAASPPLAETGAPRRFR 60
Query: 61 RSVPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQARVLAQLLRVWGAPRNSD 120
RSVPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQARVLAQLLRVWGAPRNSD
Sbjct: 61 RSVPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQARVLAQLLRVWGAPRNSD 120
Query: 121 PALGLDDDPDAPAAQLARALLRARLDPAALAAQLVPAPVPAAALRPRPPVYDDGPAGPDA 180
PALGLDDDPDAPAAQLARALLRARLDPAALAAQLVPAPVPAAALRPRPPVYDDGPAGPDA
Sbjct: 121 PALGLDDDPDAPAAQLARALLRARLDPAALAAQLVPAPVPAAALRPRPPVYDDGPAGPDA 180
Query: 181 EEAGDETPDVDPELLRYLLGRILAGSADSEGVAAPRRLRRAADHDVGSELPPEGVLGALL 240
EEAGDETPDVDPELLRYLLGRILAGSADSEGVAAPRRLRRAADHDVGSELPPEGVLGALL
Sbjct: 181 EEAGDETPDVDPELLRYLLGRILAGSADSEGVAAPRRLRRAADHDVGSELPPEGVLGALL 240
Query: 241 RVKRLETPAPQVPARRLLPP 260
RVKRLETPAPQVPARRLLPP
Sbjct: 241 RVKRLETPAPQVPARRLLPP 260
>gi|117938759 GNAS complex locus XLas [Homo sapiens]
Length = 1037
Score = 43.1 bits (100), Expect = 2e-04
Identities = 57/198 (28%), Positives = 70/198 (35%), Gaps = 36/198 (18%)
Query: 86 ERQERARAEAQEAEDQQARVLAQLLRV----WGAPR----------NSDPALGLDDDPDA 131
ER ER E + AE + A A+ +V +G+P + PA D D A
Sbjct: 347 ERAERPPVEEEAAEMEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGA 406
Query: 132 PAAQLARALLRARLDPAALAAQLVPAPVPAAALRPRPPVYDDGPAGPDAEEAGDETPDVD 191
A D A AA PAA P D PA PD+ A D D D
Sbjct: 407 TPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPD 466
Query: 192 PELLRYLLGRILAGSADSEGVAAPRRLRRAADH------DVGSELPPEGVLGALLRVKRL 245
AG+A E AAP A H D G+ P +V+R
Sbjct: 467 ------------AGAA-PEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRA 513
Query: 246 ETPAPQVPARR---LLPP 260
+ AP ARR L PP
Sbjct: 514 ASAAPASGARRKIHLRPP 531
Score = 29.6 bits (65), Expect = 2.8
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 11/82 (13%)
Query: 131 APAAQLARALLRARLDPAALAAQLVPAPVP-----------AAALRPRPPVYDDGPAGPD 179
A AA + A + L P + Q P P + + R R YD+G A D
Sbjct: 514 ASAAPASGARRKIHLRPPSPEIQAADPPTPRPTRASAWRGKSESSRGRRVYYDEGVASSD 573
Query: 180 AEEAGDETPDVDPELLRYLLGR 201
+ +GDE+ D LR+ R
Sbjct: 574 DDSSGDESDDGTSGCLRWFQHR 595
>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 43.1 bits (100), Expect = 2e-04
Identities = 47/170 (27%), Positives = 70/170 (41%), Gaps = 9/170 (5%)
Query: 23 LGLFRPPPALCARPVKEPRGLSAASPPLAETGAPRRFRRSVPRGEAAG--AVQELARALA 80
L L PPP P K+ +S + + + R + G +A A + A
Sbjct: 451 LTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTA 510
Query: 81 HLLEAERQERARAEAQEAEDQQARVLAQLLRVWGAPRN----SDPALGLDDDPDAPAAQL 136
+ ER+E+ R + A++++ R + + GA + +DP GL D + L
Sbjct: 511 QERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGLVLS-DNDRSLL 569
Query: 137 ARALLRARLDPAALAAQLVPAPVPAAALRPRPPVYDDGPAGPDAEEAGDE 186
R AR PAA A VPAP PA P P P GP A+ G +
Sbjct: 570 ERWTRMAR--PAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQ 617
>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 43.1 bits (100), Expect = 2e-04
Identities = 47/170 (27%), Positives = 70/170 (41%), Gaps = 9/170 (5%)
Query: 23 LGLFRPPPALCARPVKEPRGLSAASPPLAETGAPRRFRRSVPRGEAAG--AVQELARALA 80
L L PPP P K+ +S + + + R + G +A A + A
Sbjct: 451 LTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTA 510
Query: 81 HLLEAERQERARAEAQEAEDQQARVLAQLLRVWGAPRN----SDPALGLDDDPDAPAAQL 136
+ ER+E+ R + A++++ R + + GA + +DP GL D + L
Sbjct: 511 QERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGLVLS-DNDRSLL 569
Query: 137 ARALLRARLDPAALAAQLVPAPVPAAALRPRPPVYDDGPAGPDAEEAGDE 186
R AR PAA A VPAP PA P P P GP A+ G +
Sbjct: 570 ERWTRMAR--PAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQ 617
>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 43.1 bits (100), Expect = 2e-04
Identities = 47/170 (27%), Positives = 70/170 (41%), Gaps = 9/170 (5%)
Query: 23 LGLFRPPPALCARPVKEPRGLSAASPPLAETGAPRRFRRSVPRGEAAG--AVQELARALA 80
L L PPP P K+ +S + + + R + G +A A + A
Sbjct: 451 LTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTA 510
Query: 81 HLLEAERQERARAEAQEAEDQQARVLAQLLRVWGAPRN----SDPALGLDDDPDAPAAQL 136
+ ER+E+ R + A++++ R + + GA + +DP GL D + L
Sbjct: 511 QERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGLVLS-DNDRSLL 569
Query: 137 ARALLRARLDPAALAAQLVPAPVPAAALRPRPPVYDDGPAGPDAEEAGDE 186
R AR PAA A VPAP PA P P P GP A+ G +
Sbjct: 570 ERWTRMAR--PAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQ 617
>gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
sapiens]
Length = 677
Score = 43.1 bits (100), Expect = 2e-04
Identities = 47/170 (27%), Positives = 70/170 (41%), Gaps = 9/170 (5%)
Query: 23 LGLFRPPPALCARPVKEPRGLSAASPPLAETGAPRRFRRSVPRGEAAG--AVQELARALA 80
L L PPP P K+ +S + + + R + G +A A + A
Sbjct: 312 LTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTA 371
Query: 81 HLLEAERQERARAEAQEAEDQQARVLAQLLRVWGAPRN----SDPALGLDDDPDAPAAQL 136
+ ER+E+ R + A++++ R + + GA + +DP GL D + L
Sbjct: 372 QERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGLVLS-DNDRSLL 430
Query: 137 ARALLRARLDPAALAAQLVPAPVPAAALRPRPPVYDDGPAGPDAEEAGDE 186
R AR PAA A VPAP PA P P P GP A+ G +
Sbjct: 431 ERWTRMAR--PAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQ 478
>gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]
Length = 175
Score = 39.3 bits (90), Expect = 0.003
Identities = 56/172 (32%), Positives = 68/172 (39%), Gaps = 36/172 (20%)
Query: 4 SPLLWGPRAGGVGLLVLLLLGLFRPPPALCA--RPVKEPRGLSAASPPLAETGAPRRFRR 61
+PL++GP GL PPP A RP +EP G PP A T P R
Sbjct: 27 APLMFGP-------------GLRDPPPPRPAPPRPGEEP-GNRHPPPPAARTH-PGSCRA 71
Query: 62 SVPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQARVLAQLLR-VWGAPRNSD 120
P AAG ++ A A ++RA A A ++ RV A+ L AP
Sbjct: 72 RCP-SPAAGGLRGPWTA------APGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGR 124
Query: 121 PALGLDDDPDAPAAQLARALLRARLDPAALAA----QLVPAPVPAAALRPRP 168
AL L P P R RL PA LA P+P PA RP P
Sbjct: 125 DALRLPPPPPPPPE-------RPRLPPAGLAGGPADSAPPSPAPAPRSRPAP 169
>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
Length = 2303
Score = 37.7 bits (86), Expect = 0.010
Identities = 43/143 (30%), Positives = 58/143 (40%), Gaps = 11/143 (7%)
Query: 32 LCARPVKEPRGLSAASPPLAETGAPRRFRRSVPRGEAAGAVQELARALAHLLEAERQERA 91
L RP K +A SP R +R++ EA + LA+AL HL E+Q
Sbjct: 695 LAHRPAKHQAAATAVSPGSCVPSLYVRKQRAL---EAELDARHLAQALEHL---EKQGPP 748
Query: 92 RAEAQEAEDQQARVLAQLLRVWGAPRNSDPALGLDDDPDAPAAQLARALLRARLDPAALA 151
AEA + L L + G ++ G DD DAP++ A A PAAL+
Sbjct: 749 AAEAATKKP-----LPPLRHLDGLAQDYASDSGCFDDDDAPSSLAAAAATGEPASPAALS 803
Query: 152 AQLVPAPVPAAALRPRPPVYDDG 174
L + AL PP G
Sbjct: 804 LFLGSPFLQGQALARTPPTRRGG 826
>gi|83921602 solute carrier family 38, member 10 isoform a [Homo
sapiens]
Length = 1119
Score = 37.0 bits (84), Expect = 0.017
Identities = 62/239 (25%), Positives = 88/239 (36%), Gaps = 43/239 (17%)
Query: 28 PPPALCARPVKEPRGLS--AASPPL-AETGAPR-------RFRRSVPRG---EAAGAVQE 74
PPP A +P S PPL AE AP R +R V R +AA ++E
Sbjct: 630 PPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEE 689
Query: 75 LARA--LAHLLEAERQERARAEAQEAEDQQARVLAQLLRVW------------GAPR--- 117
RA L H + + + + + + DQQ ++LA + PR
Sbjct: 690 AGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIHQQRQEDEEDKPRQVE 749
Query: 118 -NSDPALGLDDDPDAP---AAQLARALLRARLDPAALAAQLVPAPVPAAALRPRPPVYDD 173
+ +P + +AP A + L LDP A PAP + L R + +
Sbjct: 750 VHQEPGAAVPRGQEAPEGKARETVENLPPLPLDPVLRAPGGRPAP--SQDLNQRSLEHSE 807
Query: 174 GPAGPDAEEAGDETPDVDPELLRYLLGRILAGSADSEGVAAPRRLRRAADHDVGSELPP 232
GP G D D PD +P + A D + AAPR + G E P
Sbjct: 808 GPVGRDPAGPPDGGPDTEPRAAQ-------AKLRDGQKDAAPRAAGTVKELPKGPEQVP 859
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 37.0 bits (84), Expect = 0.017
Identities = 54/187 (28%), Positives = 64/187 (34%), Gaps = 21/187 (11%)
Query: 34 ARPVKEPRGLSAASPPLAETGAPRRFRRSVPRGEAAGAVQELARALAHLLEAERQERARA 93
AR RG + +PP A GAP + P A A A A R A A
Sbjct: 97 ARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAA 156
Query: 94 EAQEAEDQ-QARVLAQLLRVWGAPRNSDPALGLDDDPDAPAAQLARALLRA--RLDPAAL 150
A + Q AQ AP P APAA A A R P A+
Sbjct: 157 TAPPSPGPAQPGPRAQRAAPLAAP------------PPAPAAPPAVAPPAGPRRAPPPAV 204
Query: 151 AAQLVPAP------VPAAALRPRPPVYDDGPAGPDAEEAGDETPDVDPELLRYLLGRILA 204
AA+ P P P +P PP P G G P E++RYL G A
Sbjct: 205 AAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGA 264
Query: 205 GSADSEG 211
G + G
Sbjct: 265 GGRLTRG 271
Score = 29.6 bits (65), Expect = 2.8
Identities = 57/244 (23%), Positives = 77/244 (31%), Gaps = 35/244 (14%)
Query: 28 PPPALCARPVKEPRGLSAASPP-----LAETGAPRRFRRSVPRGEAAGAVQELARALAHL 82
PPP A S+A+ P + +T R R++ P ++ + R +
Sbjct: 8 PPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPD------LERICR-MVRR 60
Query: 83 LEAERQERARAEAQEAEDQQARVLAQL---LRVWGAPRNSDPALGLDDDPDAPAAQLARA 139
ER RAE ++ Q+A + + A R P G A + A A
Sbjct: 61 RHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPA 120
Query: 140 LLRARLDPAALAAQLVPAPVPAAALRPRP---PVYDDGPAGPDAEEAGDETPDVDPELLR 196
A P A PAPV AAA P P P + G P
Sbjct: 121 AAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAP---- 176
Query: 197 YLLGRILAGSADSEGVAAPRRLRRAADHDVGSELPPEGVLGALLRVKRLETPAPQVPARR 256
L A VA P RRA V + PP P P P ++
Sbjct: 177 --LAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPP-----------LPPPPQPPAPPQQ 223
Query: 257 LLPP 260
PP
Sbjct: 224 QQPP 227
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 36.6 bits (83), Expect = 0.023
Identities = 35/101 (34%), Positives = 43/101 (42%), Gaps = 12/101 (11%)
Query: 84 EAERQER-ARAEAQEAEDQQARVLAQLLRVWGAPRNSDPALGLDDDPDAPAAQLARALLR 142
E +R ER +RAE Q AED + PR S+P +D A A + A+
Sbjct: 364 EDDRDERESRAEIQNAEDYNEIFQPKNSISRTPPRRSEPFPAPPEDDAATAKEAAKPS-- 421
Query: 143 ARLDPAALAAQLVPAPVPAAALRPRPPVYDDGPAGPDAEEA 183
A V PVP + PRPPV PA P AE A
Sbjct: 422 --------PAMDVQFPVPNLEVLPRPPVVASTPA-PKAEPA 453
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 36.6 bits (83), Expect = 0.023
Identities = 39/148 (26%), Positives = 52/148 (35%), Gaps = 10/148 (6%)
Query: 28 PPPALCARPVKEPRGLSAASPPLAETGAPRRFRRSVPRGEAAGAVQELARALAH------ 81
P PA PV + PLA A SVP +A A+ + +
Sbjct: 1784 PVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPI 1843
Query: 82 LLEAERQERARAEAQEAEDQQARVLAQLLRVWGAPRNSDPALGLDDDPDAPAAQLARALL 141
L A + A LA AP S PA + P PA+ ++
Sbjct: 1844 LASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASV- 1902
Query: 142 RARLDPAALAAQLVPAPVPAAALRPRPP 169
L PA+ +A PAP P +A P PP
Sbjct: 1903 --PLAPASASAP-APAPTPVSAPNPAPP 1927
>gi|21359951 RNA binding motif protein 42 [Homo sapiens]
Length = 480
Score = 35.8 bits (81), Expect = 0.038
Identities = 57/195 (29%), Positives = 81/195 (41%), Gaps = 27/195 (13%)
Query: 27 RPP-PALCARPVKEPRGLSAASPPLAETGAPRRFRRSV--PRGEAAGAVQELARALAHLL 83
RPP AL P+ P G PP+A P + P E A +EL L L
Sbjct: 186 RPPHQALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLEEPAAPRELGLGLGLGL 245
Query: 84 EAERQERARAEAQEAEDQQARVLAQLLRVWGAPRNSDPALGLDDDPDAPAAQLARALLRA 143
+ E++E A A E+ A V + GAP + PA+ P+ LA A+
Sbjct: 246 K-EKEEAVVAAAAGLEEASAAV---AVGAGGAP--AGPAV------IGPSLPLALAMPLP 293
Query: 144 RLDPAALAAQLVPAPVP------AAALRPRP-PVYDDGPAGPDA----EEAGDETPDVDP 192
+P L ++V +P +LRPRP P + P G A E G++ P
Sbjct: 294 EPEPLPLPLEVVRGLLPPLRIPELLSLRPRPRPPRPEPPPGLMALEVPEPLGEDKKKGKP 353
Query: 193 ELLRYLLGRILAGSA 207
E L+ + R AGS+
Sbjct: 354 EKLKRCI-RTAAGSS 367
>gi|116006967 neuregulin 1 isoform GGF2 [Homo sapiens]
Length = 422
Score = 35.4 bits (80), Expect = 0.050
Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 49/174 (28%)
Query: 17 LLVLLLLGLFRPPPALCARPVKEPRGLSA--ASPPLAETGAPRRFRRSVPRGEAAGAVQE 74
L +LLLLG P A P G S +SPP + G+VQE
Sbjct: 33 LPLLLLLGTAALAPGAAAGNEAAPAGASVCYSSPP------------------SVGSVQE 74
Query: 75 LARALAHLLEAERQERARAEAQEAEDQQARVLAQLLRVWGAPRNSDPALGLDDDPDAPAA 134
LA+ A ++E + + R Q A D++A A WG D + PAA
Sbjct: 75 LAQRAAVVIEGKVHPQRR--QQGALDRKAAAAAGEAGAWGG------------DREPPAA 120
Query: 135 QLARALLRARLDPAALAAQLVPAPVPAAALRPRPPVYDDGPAGPDAEEAGDETP 188
P AL PA P A P + P P A E G+E P
Sbjct: 121 -----------GPRALGP---PAEEPLLAANGTVPSWPTAPV-PSAGEPGEEAP 159
>gi|239755509 PREDICTED: hypothetical protein [Homo sapiens]
Length = 344
Score = 35.4 bits (80), Expect = 0.050
Identities = 42/124 (33%), Positives = 52/124 (41%), Gaps = 18/124 (14%)
Query: 30 PALC---ARPVKEPRGLSAASPPLAETGAPRRFRRSVPRGEAAG-----AVQELARALAH 81
P+ C A P+ PR A P LA PR R+ V RG G A + LA ALA
Sbjct: 14 PSRCSPSALPLTSPRRPRAPPPTLAPHLRPRHLRKEVERGGPLGPVRVPAARALALALAL 73
Query: 82 LLEAERQERA---RAEAQEAEDQQARVLAQLLRVWG---APRNSDPA----LGLDDDPDA 131
L A R+ A + +A ++ LL V G PR D LGL P A
Sbjct: 74 ALAAGRRLLAGLGLGRPRSRPPGRALLVVVLLVVLGPGSVPRRVDQVHLQHLGLQPAPRA 133
Query: 132 PAAQ 135
AA+
Sbjct: 134 AAAR 137
>gi|239750019 PREDICTED: hypothetical protein [Homo sapiens]
Length = 344
Score = 35.4 bits (80), Expect = 0.050
Identities = 42/124 (33%), Positives = 52/124 (41%), Gaps = 18/124 (14%)
Query: 30 PALC---ARPVKEPRGLSAASPPLAETGAPRRFRRSVPRGEAAG-----AVQELARALAH 81
P+ C A P+ PR A P LA PR R+ V RG G A + LA ALA
Sbjct: 14 PSRCSPSALPLTSPRRPRAPPPTLAPHLRPRHLRKEVERGGPLGPVRVPAARALALALAL 73
Query: 82 LLEAERQERA---RAEAQEAEDQQARVLAQLLRVWG---APRNSDPA----LGLDDDPDA 131
L A R+ A + +A ++ LL V G PR D LGL P A
Sbjct: 74 ALAAGRRLLAGLGLGRPRSRPPGRALLVVVLLVVLGPGSVPRRVDQVHLQHLGLQPAPRA 133
Query: 132 PAAQ 135
AA+
Sbjct: 134 AAAR 137
>gi|239744332 PREDICTED: hypothetical protein XP_002343119 [Homo
sapiens]
Length = 344
Score = 35.4 bits (80), Expect = 0.050
Identities = 42/124 (33%), Positives = 52/124 (41%), Gaps = 18/124 (14%)
Query: 30 PALC---ARPVKEPRGLSAASPPLAETGAPRRFRRSVPRGEAAG-----AVQELARALAH 81
P+ C A P+ PR A P LA PR R+ V RG G A + LA ALA
Sbjct: 14 PSRCSPSALPLTSPRRPRAPPPTLAPHLRPRHLRKEVERGGPLGPVRVPAARALALALAL 73
Query: 82 LLEAERQERA---RAEAQEAEDQQARVLAQLLRVWG---APRNSDPA----LGLDDDPDA 131
L A R+ A + +A ++ LL V G PR D LGL P A
Sbjct: 74 ALAAGRRLLAGLGLGRPRSRPPGRALLVVVLLVVLGPGSVPRRVDQVHLQHLGLQPAPRA 133
Query: 132 PAAQ 135
AA+
Sbjct: 134 AAAR 137
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 35.0 bits (79), Expect = 0.066
Identities = 68/252 (26%), Positives = 93/252 (36%), Gaps = 20/252 (7%)
Query: 22 LLGLFRPP----PALCARPVKEPRGLSAASPPLAETGAPRRFRRSVPRGEAAGAVQELA- 76
LL PP PA P+ E ++A AE +P EA+ +Q LA
Sbjct: 476 LLAATEPPADETPAEARSPLSEE---TSAEEAHAEVQSP--LAEETTAEEASAEIQLLAA 530
Query: 77 -RALAHLLEAERQERARAE--AQEAEDQQARVLAQLLRVWGAPRNSDPALGLDDDPDAPA 133
A A AE Q E A+EA + A+ + + AP P G ++ A
Sbjct: 531 IEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSG--EETTAEE 588
Query: 134 AQLARALLRARLDPAALA-AQLVPAPVPAAALRPRPPVYDDGPA---GPDAEEAGDETPD 189
A A LL A A A A++ P P A +PP ++ PA P AEEA E
Sbjct: 589 ASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP 648
Query: 190 VDPELLRYLLGRILAGSADSEGVAAPRRLRRAADHDV-GSELPPEGVLGALLRVKRLETP 248
E + A A +E P A + E P E L A+ + P
Sbjct: 649 PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVP 708
Query: 249 APQVPARRLLPP 260
A + + PP
Sbjct: 709 AEEASVDKHSPP 720
>gi|191252785 centrobin, centrosomal BRCA2 interacting protein
isoform alpha [Homo sapiens]
Length = 903
Score = 35.0 bits (79), Expect = 0.066
Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 12/114 (10%)
Query: 73 QELARALAHLLEAERQERARAEAQEAEDQQARVLAQLLRVWGAPRNSDPALGLDDDPDAP 132
QELA LA + E ER + Q AED + R+ + RV + ++
Sbjct: 494 QELASQLAQF-KVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQL----EEQRVE 548
Query: 133 AAQLARALLRARLDPAALAAQLVPAPVPAAALRPRPPVYDDGPAGPDAEEAGDE 186
+ +A+L+A D A QL+ +P P PP GP+ P +E E
Sbjct: 549 LVERLQAMLQAHWDEAN---QLLSTTLPP----PNPPAPPAGPSSPGPQEPEKE 595
>gi|80861396 centrobin, centrosomal BRCA2 interacting protein
isoform beta [Homo sapiens]
Length = 925
Score = 35.0 bits (79), Expect = 0.066
Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 12/114 (10%)
Query: 73 QELARALAHLLEAERQERARAEAQEAEDQQARVLAQLLRVWGAPRNSDPALGLDDDPDAP 132
QELA LA + E ER + Q AED + R+ + RV + ++
Sbjct: 494 QELASQLAQF-KVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQL----EEQRVE 548
Query: 133 AAQLARALLRARLDPAALAAQLVPAPVPAAALRPRPPVYDDGPAGPDAEEAGDE 186
+ +A+L+A D A QL+ +P P PP GP+ P +E E
Sbjct: 549 LVERLQAMLQAHWDEAN---QLLSTTLPP----PNPPAPPAGPSSPGPQEPEKE 595
>gi|71274172 ankyrin repeat domain 56 [Homo sapiens]
Length = 793
Score = 35.0 bits (79), Expect = 0.066
Identities = 60/221 (27%), Positives = 67/221 (30%), Gaps = 56/221 (25%)
Query: 24 GLFRP--PPALC-----ARPVKEPRGLSAASPPLAETGAPRRFRRSV-PRGEAAGAVQEL 75
GL RP PPA A P PRG PP + PRR RR P E AGA
Sbjct: 85 GLQRPREPPAAAPSAGGAAPCS-PRGARRGEPPQQQ---PRRRRREKEPEEEPAGAAARA 140
Query: 76 ARALAHLLEAERQERARAE---------------AQEAEDQQARVLAQLLRVWG------ 114
A A + L RA + A A QAR + G
Sbjct: 141 ADAACNGLPGSDSRRAPGKGGGSKGSPGQRPPVPAAAAAGAQARASCAAAKTQGRCCWEC 200
Query: 115 ------------------APRNSDPALGLDDDPDAPAAQLARALLRARLDPAALAAQLVP 156
A PA L D A++ A P A P
Sbjct: 201 LQNNLAVLPGELGALPHSATAEEKPARALPAQDDRGASREREEGALAEPAPVPAVAHSPP 260
Query: 157 APVPAAALRPRPPVYDDGPAGPDAEEAGDETPDVDPELLRY 197
A V AA R PP GPA GD + P L Y
Sbjct: 261 ATVEAATSRASPPALLPGPA-----PRGDRPELLTPSSLHY 296
>gi|24431933 reticulon 4 isoform B [Homo sapiens]
Length = 373
Score = 34.7 bits (78), Expect = 0.086
Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 19/128 (14%)
Query: 84 EAERQERARAEAQEAEDQQARVLAQLLR-----VWGAPRNSDPALGL-------DDDPDA 131
E E +E E +E ED+ L L R + AP + PA G D P A
Sbjct: 30 EPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPA 89
Query: 132 PAAQLARALLRA-----RLDPAALAAQL-VPAPVPAAALRP-RPPVYDDGPAGPDAEEAG 184
P L A A DP+ +++ + P+P+ AAA+ P + P D+ PA P
Sbjct: 90 PRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPA 149
Query: 185 DETPDVDP 192
+P +P
Sbjct: 150 SVSPQAEP 157
>gi|47519490 reticulon 4 isoform D [Homo sapiens]
Length = 392
Score = 34.7 bits (78), Expect = 0.086
Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 19/128 (14%)
Query: 84 EAERQERARAEAQEAEDQQARVLAQLLR-----VWGAPRNSDPALGL-------DDDPDA 131
E E +E E +E ED+ L L R + AP + PA G D P A
Sbjct: 30 EPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPA 89
Query: 132 PAAQLARALLRA-----RLDPAALAAQL-VPAPVPAAALRP-RPPVYDDGPAGPDAEEAG 184
P L A A DP+ +++ + P+P+ AAA+ P + P D+ PA P
Sbjct: 90 PRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPA 149
Query: 185 DETPDVDP 192
+P +P
Sbjct: 150 SVSPQAEP 157
>gi|24431935 reticulon 4 isoform A [Homo sapiens]
Length = 1192
Score = 34.7 bits (78), Expect = 0.086
Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 19/128 (14%)
Query: 84 EAERQERARAEAQEAEDQQARVLAQLLR-----VWGAPRNSDPALGL-------DDDPDA 131
E E +E E +E ED+ L L R + AP + PA G D P A
Sbjct: 30 EPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPA 89
Query: 132 PAAQLARALLRA-----RLDPAALAAQL-VPAPVPAAALRP-RPPVYDDGPAGPDAEEAG 184
P L A A DP+ +++ + P+P+ AAA+ P + P D+ PA P
Sbjct: 90 PRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPA 149
Query: 185 DETPDVDP 192
+P +P
Sbjct: 150 SVSPQAEP 157
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 34.7 bits (78), Expect = 0.086
Identities = 40/159 (25%), Positives = 54/159 (33%), Gaps = 11/159 (6%)
Query: 30 PALCARPVKEPRGLSAASPPLAETGAPRRFRRSVPRGEAAGAVQELARALAHLLEAERQE 89
P P P A +P LA R VP A+ V A A ++
Sbjct: 505 PTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETA----APVED 560
Query: 90 RARAEAQEAEDQQARVLAQLLRVWGAPRNSDPALGLDDDPDAPAAQLARALLRARLDPAA 149
AR + A + Q+ R+S PA L +P A L RL ++
Sbjct: 561 MARRTKRPAPARPTMPPPQV----SGSRSSPPAPPLPPGSGSPGTPQA---LPRRLVGSS 613
Query: 150 LAAQLVPAPVPAAALRPRPPVYDDGPAGPDAEEAGDETP 188
L A VP P+P +P PA P G +P
Sbjct: 614 LRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGPASP 652
>gi|157364934 fibrosin [Homo sapiens]
Length = 460
Score = 34.3 bits (77), Expect = 0.11
Identities = 63/237 (26%), Positives = 85/237 (35%), Gaps = 43/237 (18%)
Query: 26 FRPPPALCARPVKEPRGLSA-ASPPLAETGAPRRFRRSVPRGEAAGAVQELARALAHLLE 84
F PP R + P A PP A R V R E + +E R L
Sbjct: 217 FASPPDPWGRLHRSPLTFPAWVRPPEAARTPGSDKERPVERREPSITKEEKDRDLPFSRP 276
Query: 85 AERQERARAEAQEAEDQQARVLAQLLRVWGAPRNSDPALGLDDDPDAPAAQLARALLRAR 144
R A +A+ E+ PR + ++ + ++ AA A A A
Sbjct: 277 QLRVSPATPKARAGEE--------------GPRPTKESVRVKEERKEEAAAAAAAAAAAA 322
Query: 145 LDPAALAAQLVPAPVPAAALRPRPPVYDDGPAGPDAEEAGDETPDVDPELLRYLLGRILA 204
AA AA P + RPRPP + GP+ PD A
Sbjct: 323 A--AAAAAATGPQGLHLLFERPRPPPF-LGPSPPDR----------------------CA 357
Query: 205 GSADSEGVAAPRRLRRAAD-HDVGSELPPEGVLGALLRVKRLETPAPQVPARRLLPP 260
G + +AAP RL R ++ G EL G + A R+ LE PA + RL PP
Sbjct: 358 GFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVAA-ARLYGLE-PAHPLLYSRLAPP 412
>gi|239756307 PREDICTED: similar to ubiquitin-associated protein 1
(predicted) [Homo sapiens]
Length = 290
Score = 33.9 bits (76), Expect = 0.15
Identities = 39/140 (27%), Positives = 52/140 (37%), Gaps = 18/140 (12%)
Query: 40 PRGLSAASPPLAETGAPRRFRRSVPRGEAAGAVQELARALAHLLEAERQERARAEAQEAE 99
P L SP +P RR G ELA A L E + R RA
Sbjct: 125 PSSLQPGSP-----ASPGPGRRLCSLDVLRGVRLELAGARRRLSEGKLVSRPRALLHGLR 179
Query: 100 DQQARVLAQLLRVWGAPRNSDPALGLDDDPDAPAA----QLARALLRARLDPAALAAQLV 155
+A L +PR++ P P APA+ A A+ R +A +++
Sbjct: 180 GHRALSLCPSPAQ--SPRSASPPGPAPQHPAAPASPPRPSTAGAIPPLRSHKPTVAVRIL 237
Query: 156 PAPVPAAALRPRPPVYDDGP 175
PAP PRPP+ GP
Sbjct: 238 PAP-------PRPPISSPGP 250
>gi|169165603 PREDICTED: similar to proline rich 20 [Homo sapiens]
Length = 210
Score = 33.9 bits (76), Expect = 0.15
Identities = 37/152 (24%), Positives = 64/152 (42%), Gaps = 31/152 (20%)
Query: 30 PALCARPVK-EPRGLSAASPPLAETGAPRR----FRRSVPRGEAAGAVQELARA------ 78
P +P++ EP + +PP G +R +R RG AG ++ L
Sbjct: 45 PTAYVKPMRREPPARAQPAPP---AGRGQRGGGSWRAGRGRGSGAGLLRALGERVGPGMY 101
Query: 79 LAHLLE-AERQERARAEAQEAED---QQARVLAQLLRVWGAPRNSDPALGLDDDPDAPAA 134
L HL + E + + EA++ +A ++ +++ P + P +GL + P AP
Sbjct: 102 LVHLNDHGELGYQGQLEARQTPAFSFTEAALMPGIVQEGPGPHAAQPEVGLQEPPPAPG- 160
Query: 135 QLARALLRARLDPAALAAQLVPAPVPAAALRP 166
P A+A Q + AP P+ + RP
Sbjct: 161 ------------PVAVARQTMLAPSPSLSFRP 180
>gi|239750857 PREDICTED: similar to ubiquitin-associated protein 1
(predicted) [Homo sapiens]
Length = 290
Score = 33.9 bits (76), Expect = 0.15
Identities = 39/140 (27%), Positives = 52/140 (37%), Gaps = 18/140 (12%)
Query: 40 PRGLSAASPPLAETGAPRRFRRSVPRGEAAGAVQELARALAHLLEAERQERARAEAQEAE 99
P L SP +P RR G ELA A L E + R RA
Sbjct: 125 PSSLQPGSP-----ASPGPGRRLCSLDVLRGVRLELAGARRRLSEGKLVSRPRALLHGLR 179
Query: 100 DQQARVLAQLLRVWGAPRNSDPALGLDDDPDAPAA----QLARALLRARLDPAALAAQLV 155
+A L +PR++ P P APA+ A A+ R +A +++
Sbjct: 180 GHRALSLCPSPAQ--SPRSASPPGPAPQHPAAPASPPRPSTAGAIPPLRSHKPTVAVRIL 237
Query: 156 PAPVPAAALRPRPPVYDDGP 175
PAP PRPP+ GP
Sbjct: 238 PAP-------PRPPISSPGP 250
>gi|169166067 PREDICTED: similar to proline rich 20 [Homo sapiens]
Length = 210
Score = 33.9 bits (76), Expect = 0.15
Identities = 37/152 (24%), Positives = 64/152 (42%), Gaps = 31/152 (20%)
Query: 30 PALCARPVK-EPRGLSAASPPLAETGAPRR----FRRSVPRGEAAGAVQELARA------ 78
P +P++ EP + +PP G +R +R RG AG ++ L
Sbjct: 45 PTAYVKPMRREPPARAQPAPP---AGRGQRGGGSWRAGRGRGSGAGLLRALGERVGPGMY 101
Query: 79 LAHLLE-AERQERARAEAQEAED---QQARVLAQLLRVWGAPRNSDPALGLDDDPDAPAA 134
L HL + E + + EA++ +A ++ +++ P + P +GL + P AP
Sbjct: 102 LVHLNDHGELGYQGQLEARQTPAFSFTEAALMPGIVQEGPGPHAAQPEVGLQEPPPAPG- 160
Query: 135 QLARALLRARLDPAALAAQLVPAPVPAAALRP 166
P A+A Q + AP P+ + RP
Sbjct: 161 ------------PVAVARQTMLAPSPSLSFRP 180
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.136 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,336,555
Number of Sequences: 37866
Number of extensions: 710496
Number of successful extensions: 4649
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 229
Number of HSP's that attempted gapping in prelim test: 4223
Number of HSP's gapped (non-prelim): 600
length of query: 260
length of database: 18,247,518
effective HSP length: 100
effective length of query: 160
effective length of database: 14,460,918
effective search space: 2313746880
effective search space used: 2313746880
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.