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Search of human proteins with 7019351
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7019351 cardiotrophin-like cytokine factor 1 [Homo sapiens]
(225 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7019351 cardiotrophin-like cytokine factor 1 [Homo sapiens] 476 e-135
gi|216548056 cardiotrophin 1 isoform 2 [Homo sapiens] 35 0.040
gi|4503121 cardiotrophin 1 isoform 1 [Homo sapiens] 35 0.040
gi|28416913 interleukin 27 [Homo sapiens] 34 0.088
gi|208431817 protein kinase-like protein SgK493 [Homo sapiens] 32 0.34
gi|169211642 PREDICTED: hypothetical protein [Homo sapiens] 32 0.57
gi|169210857 PREDICTED: similar to RIKEN cDNA E130309D14 [Homo s... 32 0.57
gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens] 29 3.7
gi|239755499 PREDICTED: hypothetical protein [Homo sapiens] 28 4.8
gi|239750031 PREDICTED: hypothetical protein [Homo sapiens] 28 4.8
gi|239744342 PREDICTED: hypothetical protein XP_002343123 [Homo ... 28 4.8
gi|189027048 ecto-NOX disulfide-thiol exchanger 1 [Homo sapiens] 28 4.8
gi|189027046 ecto-NOX disulfide-thiol exchanger 1 [Homo sapiens] 28 4.8
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi... 28 4.8
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi... 28 4.8
gi|40217833 G protein-coupled receptor family C, group 5, member... 28 4.8
gi|94536743 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B [Ho... 28 4.8
gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens] 28 4.8
gi|40217831 G protein-coupled receptor family C, group 5, member... 28 4.8
gi|223633935 hypothetical protein LOC254427 [Homo sapiens] 28 8.3
gi|32528293 ecto-NOX disulfide-thiol exchanger 2 isoform a [Homo... 28 8.3
gi|32528291 ecto-NOX disulfide-thiol exchanger 2 isoform b [Homo... 28 8.3
gi|24497526 homeobox B1 [Homo sapiens] 28 8.3
gi|52630447 palmitoylated membrane protein 2 [Homo sapiens] 28 8.3
>gi|7019351 cardiotrophin-like cytokine factor 1 [Homo sapiens]
Length = 225
Score = 476 bits (1226), Expect = e-135
Identities = 225/225 (100%), Positives = 225/225 (100%)
Query: 1 MDLRAGDSWGMLACLCTVLWHLPAVPALNRTGDPGPGPSIQKTYDLTRYLEHQLRSLAGT 60
MDLRAGDSWGMLACLCTVLWHLPAVPALNRTGDPGPGPSIQKTYDLTRYLEHQLRSLAGT
Sbjct: 1 MDLRAGDSWGMLACLCTVLWHLPAVPALNRTGDPGPGPSIQKTYDLTRYLEHQLRSLAGT 60
Query: 61 YLNYLGPPFNEPDFNPPRLGAETLPRATVDLEVWRSLNDKLRLTQNYEAYSHLLCYLRGL 120
YLNYLGPPFNEPDFNPPRLGAETLPRATVDLEVWRSLNDKLRLTQNYEAYSHLLCYLRGL
Sbjct: 61 YLNYLGPPFNEPDFNPPRLGAETLPRATVDLEVWRSLNDKLRLTQNYEAYSHLLCYLRGL 120
Query: 121 NRQAATAELRRSLAHFCTSLQGLLGSIAGVMAALGYPLPQPLPGTEPTWTPGPAHSDFLQ 180
NRQAATAELRRSLAHFCTSLQGLLGSIAGVMAALGYPLPQPLPGTEPTWTPGPAHSDFLQ
Sbjct: 121 NRQAATAELRRSLAHFCTSLQGLLGSIAGVMAALGYPLPQPLPGTEPTWTPGPAHSDFLQ 180
Query: 181 KMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPAAAVTLHLGAHGF 225
KMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPAAAVTLHLGAHGF
Sbjct: 181 KMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPAAAVTLHLGAHGF 225
>gi|216548056 cardiotrophin 1 isoform 2 [Homo sapiens]
Length = 200
Score = 35.4 bits (80), Expect = 0.040
Identities = 45/174 (25%), Positives = 69/174 (39%), Gaps = 13/174 (7%)
Query: 40 IQKTYDLTRYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGAETLPRATVDLEVWRSLND 99
I++T+ L L L Y+ G PF P F+PPRL L A +++
Sbjct: 26 IRQTHSLAHLLTKYAEQLLQEYVQLQGDPFGLPSFSPPRLPVAGL-SAPAPSHAGLPVHE 84
Query: 100 KLRLTQNYEAYSHLLCYLRGLNRQAA-----TAELRRSLAHFCTSLQGLLGSIAGVMAAL 154
+LRL + A + L L + R+ A L R L + L ++ ++AAL
Sbjct: 85 RLRL--DAAALAALPPLLDAVCRRQAELNPRAPRLLRRLEDAARQARALGAAVEALLAAL 142
Query: 155 GYPLPQPLPGTEP---TWTPGPAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRL 205
G P EP T + A F K+ + + WL R+ D +L
Sbjct: 143 G--AANRGPRAEPPAATASAASATGVFPAKVLGLRVCGLYREWLSRTEGDLGQL 194
>gi|4503121 cardiotrophin 1 isoform 1 [Homo sapiens]
Length = 201
Score = 35.4 bits (80), Expect = 0.040
Identities = 45/174 (25%), Positives = 69/174 (39%), Gaps = 13/174 (7%)
Query: 40 IQKTYDLTRYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGAETLPRATVDLEVWRSLND 99
I++T+ L L L Y+ G PF P F+PPRL L A +++
Sbjct: 27 IRQTHSLAHLLTKYAEQLLQEYVQLQGDPFGLPSFSPPRLPVAGL-SAPAPSHAGLPVHE 85
Query: 100 KLRLTQNYEAYSHLLCYLRGLNRQAA-----TAELRRSLAHFCTSLQGLLGSIAGVMAAL 154
+LRL + A + L L + R+ A L R L + L ++ ++AAL
Sbjct: 86 RLRL--DAAALAALPPLLDAVCRRQAELNPRAPRLLRRLEDAARQARALGAAVEALLAAL 143
Query: 155 GYPLPQPLPGTEP---TWTPGPAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRL 205
G P EP T + A F K+ + + WL R+ D +L
Sbjct: 144 G--AANRGPRAEPPAATASAASATGVFPAKVLGLRVCGLYREWLSRTEGDLGQL 195
>gi|28416913 interleukin 27 [Homo sapiens]
Length = 243
Score = 34.3 bits (77), Expect = 0.088
Identities = 35/142 (24%), Positives = 53/142 (37%), Gaps = 16/142 (11%)
Query: 82 ETLPRATVDLEVWRSLNDKLRLTQNYEAYSHLLCYLRGLNRQAATAELRR-SLAHFCTSL 140
E LP ++ + WR L+D RL L GL Q + R L L
Sbjct: 85 EQLPDVSLTFQAWRRLSDPERLCFISTTLQPFHALLGGLGTQGRWTNMERMQLWAMRLDL 144
Query: 141 QGLLGSIAGVMAALGYPLPQP---------------LPGTEPTWTPGPAHSDFLQKMDDF 185
+ L + + A G+ LP+ LPG + GPA + Q + +
Sbjct: 145 RDLQRHLRFQVLAAGFNLPEEEEEEEEEEEEERKGLLPGALGSALQGPAQVSWPQLLSTY 204
Query: 186 WLLKELQTWLWRSAKDFNRLKK 207
LL L+ L R+ ++ L K
Sbjct: 205 RLLHSLELVLSRAVRELLLLSK 226
>gi|208431817 protein kinase-like protein SgK493 [Homo sapiens]
Length = 493
Score = 32.3 bits (72), Expect = 0.34
Identities = 22/52 (42%), Positives = 27/52 (51%), Gaps = 8/52 (15%)
Query: 122 RQAATAELRRSLAHFCTSLQGLLGSIAGVMAALGYPLPQPLPGTEPTWTPGP 173
R+AA A A FC S LLGS+ V+ A G P+P EP+ PGP
Sbjct: 4 RRAAVA------AGFCASF--LLGSVLNVLFAPGSEPPRPGQSPEPSPAPGP 47
>gi|169211642 PREDICTED: hypothetical protein [Homo sapiens]
Length = 378
Score = 31.6 bits (70), Expect = 0.57
Identities = 31/97 (31%), Positives = 40/97 (41%), Gaps = 15/97 (15%)
Query: 48 RYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGAETLPRATVDLEVWRSLNDKLRLT--- 104
R + L++L G + P F P F PP G + TV L+V+ L L +
Sbjct: 91 RGVTRPLKALLGGGPRDVPPSFPNPRFTPPPRGHQ-----TVSLQVYTELTHDLEMREAQ 145
Query: 105 --QNYEAYSHLLCYLRGLN-----RQAATAELRRSLA 134
Q A L R L R AA AELRR +A
Sbjct: 146 SHQQEAASRELESKCRALESQLEARAAANAELRREVA 182
>gi|169210857 PREDICTED: similar to RIKEN cDNA E130309D14 [Homo
sapiens]
Length = 378
Score = 31.6 bits (70), Expect = 0.57
Identities = 31/97 (31%), Positives = 40/97 (41%), Gaps = 15/97 (15%)
Query: 48 RYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGAETLPRATVDLEVWRSLNDKLRLT--- 104
R + L++L G + P F P F PP G + TV L+V+ L L +
Sbjct: 91 RGVTRPLKALLGGGPRDVPPSFPNPRFTPPPRGHQ-----TVSLQVYTELTHDLEMREAQ 145
Query: 105 --QNYEAYSHLLCYLRGLN-----RQAATAELRRSLA 134
Q A L R L R AA AELRR +A
Sbjct: 146 SHQQEAASRELESKCRALESQLEARAAANAELRREVA 182
>gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]
Length = 870
Score = 28.9 bits (63), Expect = 3.7
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
Query: 120 LNRQAATAELRRSLAHFCTSLQGLLGSIAGV--MAALGYPLP 159
L+RQA A++R + H+ L LL I AAL YP P
Sbjct: 799 LSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSP 840
>gi|239755499 PREDICTED: hypothetical protein [Homo sapiens]
Length = 516
Score = 28.5 bits (62), Expect = 4.8
Identities = 23/76 (30%), Positives = 27/76 (35%), Gaps = 18/76 (23%)
Query: 125 ATAELRRSLAHFCTSLQGLLGSIAGVM------AALGYPLPQPLPGTEPTWTPGPAHSDF 178
A E+R L H C LQ LL + V LG LP P PTW
Sbjct: 326 APHEVRALLQHLCPHLQCLLCLVGLVQLEPLLDLLLGLVLPHPPQALCPTWG-------- 377
Query: 179 LQKMDDFWLLKELQTW 194
D +WL +W
Sbjct: 378 ----DPWWLRASRHSW 389
>gi|239750031 PREDICTED: hypothetical protein [Homo sapiens]
Length = 356
Score = 28.5 bits (62), Expect = 4.8
Identities = 23/76 (30%), Positives = 27/76 (35%), Gaps = 18/76 (23%)
Query: 125 ATAELRRSLAHFCTSLQGLLGSIAGVM------AALGYPLPQPLPGTEPTWTPGPAHSDF 178
A E+R L H C LQ LL + V LG LP P PTW
Sbjct: 166 APHEVRALLQHLCPHLQCLLCLVGLVQLEPLLDLLLGLVLPHPPQALCPTWG-------- 217
Query: 179 LQKMDDFWLLKELQTW 194
D +WL +W
Sbjct: 218 ----DPWWLRASRHSW 229
>gi|239744342 PREDICTED: hypothetical protein XP_002343123 [Homo
sapiens]
Length = 356
Score = 28.5 bits (62), Expect = 4.8
Identities = 23/76 (30%), Positives = 27/76 (35%), Gaps = 18/76 (23%)
Query: 125 ATAELRRSLAHFCTSLQGLLGSIAGVM------AALGYPLPQPLPGTEPTWTPGPAHSDF 178
A E+R L H C LQ LL + V LG LP P PTW
Sbjct: 166 APHEVRALLQHLCPHLQCLLCLVGLVQLEPLLDLLLGLVLPHPPQALCPTWG-------- 217
Query: 179 LQKMDDFWLLKELQTW 194
D +WL +W
Sbjct: 218 ----DPWWLRASRHSW 229
>gi|189027048 ecto-NOX disulfide-thiol exchanger 1 [Homo sapiens]
Length = 643
Score = 28.5 bits (62), Expect = 4.8
Identities = 15/53 (28%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 172 GPAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRLKK-KMQPPAAAVTLHLGAH 223
G H DF Q DDF+ + Q R + +L++ +++PP+ +H H
Sbjct: 212 GRLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPAIMHYSEH 264
>gi|189027046 ecto-NOX disulfide-thiol exchanger 1 [Homo sapiens]
Length = 643
Score = 28.5 bits (62), Expect = 4.8
Identities = 15/53 (28%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 172 GPAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRLKK-KMQPPAAAVTLHLGAH 223
G H DF Q DDF+ + Q R + +L++ +++PP+ +H H
Sbjct: 212 GRLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPAIMHYSEH 264
>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
sapiens]
Length = 491
Score = 28.5 bits (62), Expect = 4.8
Identities = 15/64 (23%), Positives = 30/64 (46%)
Query: 101 LRLTQNYEAYSHLLCYLRGLNRQAATAELRRSLAHFCTSLQGLLGSIAGVMAALGYPLPQ 160
+ L NY+ + + Y+ + R +++ F + LL S+A V+ G P+P+
Sbjct: 373 VNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPE 432
Query: 161 PLPG 164
+ G
Sbjct: 433 YIKG 436
>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
sapiens]
Length = 599
Score = 28.5 bits (62), Expect = 4.8
Identities = 15/64 (23%), Positives = 30/64 (46%)
Query: 101 LRLTQNYEAYSHLLCYLRGLNRQAATAELRRSLAHFCTSLQGLLGSIAGVMAALGYPLPQ 160
+ L NY+ + + Y+ + R +++ F + LL S+A V+ G P+P+
Sbjct: 481 VNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPE 540
Query: 161 PLPG 164
+ G
Sbjct: 541 YIKG 544
>gi|40217833 G protein-coupled receptor family C, group 5, member C
isoform b [Homo sapiens]
Length = 453
Score = 28.5 bits (62), Expect = 4.8
Identities = 14/29 (48%), Positives = 16/29 (55%)
Query: 84 LPRATVDLEVWRSLNDKLRLTQNYEAYSH 112
LPRAT + +V S N LR Y A SH
Sbjct: 403 LPRATANSQVMGSANSTLRAEDMYSAQSH 431
>gi|94536743 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B [Homo
sapiens]
Length = 861
Score = 28.5 bits (62), Expect = 4.8
Identities = 15/28 (53%), Positives = 16/28 (57%)
Query: 144 LGSIAGVMAALGYPLPQPLPGTEPTWTP 171
L S AGV L PL PLPG+E T P
Sbjct: 134 LTSTAGVQEELHLPLNSPLPGSELTKEP 161
>gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]
Length = 4861
Score = 28.5 bits (62), Expect = 4.8
Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 7/88 (7%)
Query: 39 SIQKTYDLTRYLEHQLRSLAGTYLNYL-GPPFNEPDFNPPRLGAETLPRATVDLEVWRSL 97
S + +DLT+ L + +L ++++ G N P F P T P+A++ + L
Sbjct: 1575 SFESDFDLTKSLG--VHTLIENVVSFVSGDVGNAPGFKEPEESMSTSPQASIIAMEQQQL 1632
Query: 98 NDKLRLTQNYEAYSHLLCYLRGLNRQAA 125
+LRL EA +L L G+ + +
Sbjct: 1633 RAELRL----EALHQILVLLSGMEEKGS 1656
>gi|40217831 G protein-coupled receptor family C, group 5, member C
isoform a [Homo sapiens]
Length = 486
Score = 28.5 bits (62), Expect = 4.8
Identities = 14/29 (48%), Positives = 16/29 (55%)
Query: 84 LPRATVDLEVWRSLNDKLRLTQNYEAYSH 112
LPRAT + +V S N LR Y A SH
Sbjct: 436 LPRATANSQVMGSANSTLRAEDMYSAQSH 464
>gi|223633935 hypothetical protein LOC254427 [Homo sapiens]
Length = 435
Score = 27.7 bits (60), Expect = 8.3
Identities = 12/20 (60%), Positives = 13/20 (65%), Gaps = 1/20 (5%)
Query: 20 WHLPAVPALNRTGDPGPGPS 39
W PA R+GDPGPGPS
Sbjct: 225 WRTPAARG-PRSGDPGPGPS 243
>gi|32528293 ecto-NOX disulfide-thiol exchanger 2 isoform a [Homo
sapiens]
Length = 581
Score = 27.7 bits (60), Expect = 8.3
Identities = 15/53 (28%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 172 GPAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRL-KKKMQPPAAAVTLHLGAH 223
G H DF Q DD + + Q L R + R+ +++++PP+ +H H
Sbjct: 169 GRLHVDFAQARDDLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDH 221
>gi|32528291 ecto-NOX disulfide-thiol exchanger 2 isoform b [Homo
sapiens]
Length = 610
Score = 27.7 bits (60), Expect = 8.3
Identities = 15/53 (28%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 172 GPAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRL-KKKMQPPAAAVTLHLGAH 223
G H DF Q DD + + Q L R + R+ +++++PP+ +H H
Sbjct: 198 GRLHVDFAQARDDLYEWECKQRMLAREERHRRRMEEERLRPPSPPPVVHYSDH 250
>gi|24497526 homeobox B1 [Homo sapiens]
Length = 301
Score = 27.7 bits (60), Expect = 8.3
Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 3/60 (5%)
Query: 156 YPLPQPLPGTEPTWTPGPAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPAAA 215
YP P G E T + PA++D L + + E T +A+ F+ +K K PP A
Sbjct: 137 YPPQHPPYGNEQTASFAPAYADLLSEDKETPCPSEPNT---PTARTFDWMKVKRNPPKTA 193
>gi|52630447 palmitoylated membrane protein 2 [Homo sapiens]
Length = 552
Score = 27.7 bits (60), Expect = 8.3
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 6/74 (8%)
Query: 106 NYEAYSHLLCYLRGLNRQAATAELRRSLAHFCTS--LQGLLGSIAGVMAALGYPLPQPLP 163
N E +L L + Q++TA LAH Q LL + V A+ Y P P P
Sbjct: 67 NLELVQEILRDLAHVAEQSSTAA---ELAHILQEPHFQSLLETHDSV-ASKTYETPPPSP 122
Query: 164 GTEPTWTPGPAHSD 177
G +PT++ P D
Sbjct: 123 GLDPTFSNQPVPPD 136
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.452
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,104,790
Number of Sequences: 37866
Number of extensions: 565669
Number of successful extensions: 2000
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1986
Number of HSP's gapped (non-prelim): 26
length of query: 225
length of database: 18,247,518
effective HSP length: 99
effective length of query: 126
effective length of database: 14,498,784
effective search space: 1826846784
effective search space used: 1826846784
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.