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Search of human proteins with 7019327
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7019327 anaphase-promoting complex subunit 2 [Homo sapiens]
(822 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7019327 anaphase-promoting complex subunit 2 [Homo sapiens] 1635 0.0
gi|169218008 PREDICTED: similar to anaphase-promoting complex su... 758 0.0
gi|57165424 cullin 4A isoform 1 [Homo sapiens] 65 2e-10
gi|11140811 cullin 4A isoform 2 [Homo sapiens] 65 2e-10
gi|121114302 cullin 4B isoform 2 [Homo sapiens] 63 1e-09
gi|121114298 cullin 4B isoform 1 [Homo sapiens] 63 1e-09
gi|32307161 cullin 1 [Homo sapiens] 60 1e-08
gi|19482174 cullin 2 [Homo sapiens] 51 4e-06
gi|4503165 cullin 3 [Homo sapiens] 42 0.002
gi|40254446 Vasopressin-activated calcium-mobilizing receptor-1 ... 41 0.004
gi|81295809 pericentrin [Homo sapiens] 37 0.057
gi|194473673 hypothetical protein LOC100170765 [Homo sapiens] 35 0.22
gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 32 2.4
gi|110349721 titin isoform novex-3 [Homo sapiens] 32 3.1
gi|224994189 prominin 1 isoform 2 [Homo sapiens] 32 3.1
gi|224994199 prominin 1 isoform 4 [Homo sapiens] 32 3.1
gi|224994197 prominin 1 isoform 5 [Homo sapiens] 32 3.1
gi|224994195 prominin 1 isoform 6 [Homo sapiens] 32 3.1
gi|224994193 prominin 1 isoform 7 [Homo sapiens] 32 3.1
gi|224994191 prominin 1 isoform 2 [Homo sapiens] 32 3.1
gi|5174387 prominin 1 isoform 1 [Homo sapiens] 32 3.1
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 31 4.1
gi|156104883 guanine nucleotide binding protein (G protein), alp... 31 4.1
gi|239755855 PREDICTED: hypothetical protein [Homo sapiens] 31 5.3
gi|239750363 PREDICTED: hypothetical protein XP_002347382 [Homo ... 31 5.3
gi|239744667 PREDICTED: hypothetical protein XP_002343220 [Homo ... 31 5.3
gi|157384971 cyclin G associated kinase [Homo sapiens] 31 5.3
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 31 5.3
gi|188219577 ring finger protein 19B isoform a [Homo sapiens] 31 5.3
gi|148806925 EGF, latrophilin and seven transmembrane domain con... 31 5.3
>gi|7019327 anaphase-promoting complex subunit 2 [Homo sapiens]
Length = 822
Score = 1635 bits (4233), Expect = 0.0
Identities = 822/822 (100%), Positives = 822/822 (100%)
Query: 1 MAAAVVVAEGDSDSRPGQELLVAWNTVSTGLVPPAALGLVSSRTSGAVPPKEEELRAAVE 60
MAAAVVVAEGDSDSRPGQELLVAWNTVSTGLVPPAALGLVSSRTSGAVPPKEEELRAAVE
Sbjct: 1 MAAAVVVAEGDSDSRPGQELLVAWNTVSTGLVPPAALGLVSSRTSGAVPPKEEELRAAVE 60
Query: 61 VLRGHGLHSVLEEWFVEVLQNDLQANISPEFWNAISQCENSADEPQCLLLLLDAFGLLES 120
VLRGHGLHSVLEEWFVEVLQNDLQANISPEFWNAISQCENSADEPQCLLLLLDAFGLLES
Sbjct: 61 VLRGHGLHSVLEEWFVEVLQNDLQANISPEFWNAISQCENSADEPQCLLLLLDAFGLLES 120
Query: 121 RLDPYLRSLELLEKWTRLGLLMGTGAQGLREEVHTMLRGVLFFSTPRTFQEMIQRLYGCF 180
RLDPYLRSLELLEKWTRLGLLMGTGAQGLREEVHTMLRGVLFFSTPRTFQEMIQRLYGCF
Sbjct: 121 RLDPYLRSLELLEKWTRLGLLMGTGAQGLREEVHTMLRGVLFFSTPRTFQEMIQRLYGCF 180
Query: 181 LRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCSSDKQQCWCRQALEQF 240
LRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCSSDKQQCWCRQALEQF
Sbjct: 181 LRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCSSDKQQCWCRQALEQF 240
Query: 241 HQLSQVLHRLSLLERVSAEAVTTTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVGWL 300
HQLSQVLHRLSLLERVSAEAVTTTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVGWL
Sbjct: 241 HQLSQVLHRLSLLERVSAEAVTTTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVGWL 300
Query: 301 GKVFLQDGPARPASPEAGNTLRRWRCHVQRFFYRIYASLRIEELFSIVRDFPDSRPAIED 360
GKVFLQDGPARPASPEAGNTLRRWRCHVQRFFYRIYASLRIEELFSIVRDFPDSRPAIED
Sbjct: 301 GKVFLQDGPARPASPEAGNTLRRWRCHVQRFFYRIYASLRIEELFSIVRDFPDSRPAIED 360
Query: 361 LKYCLERTDQRQQLLVSLKAALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVILEVA 420
LKYCLERTDQRQQLLVSLKAALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVILEVA
Sbjct: 361 LKYCLERTDQRQQLLVSLKAALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVILEVA 420
Query: 421 CEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPASLETGQDSEDDSGEPEDW 480
CEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPASLETGQDSEDDSGEPEDW
Sbjct: 421 CEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPASLETGQDSEDDSGEPEDW 480
Query: 481 VPDPVDADPGKSSSKRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIR 540
VPDPVDADPGKSSSKRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIR
Sbjct: 481 VPDPVDADPGKSSSKRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIR 540
Query: 541 NVELLKLRFGEAPMHFCEVMLKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEF 600
NVELLKLRFGEAPMHFCEVMLKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEF
Sbjct: 541 NVELLKLRFGEAPMHFCEVMLKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEF 600
Query: 601 WPPFKDEKLEVPEDIRAALEAYCKKYEQLKAMRTLSWKHTLGLVTMDVELADRTLSVAVT 660
WPPFKDEKLEVPEDIRAALEAYCKKYEQLKAMRTLSWKHTLGLVTMDVELADRTLSVAVT
Sbjct: 601 WPPFKDEKLEVPEDIRAALEAYCKKYEQLKAMRTLSWKHTLGLVTMDVELADRTLSVAVT 660
Query: 661 PVQAVILLYFQDQASWTLEELSKAVKMPVALLRRRMSVWLQQGVLREEPPGTFSVIEEER 720
PVQAVILLYFQDQASWTLEELSKAVKMPVALLRRRMSVWLQQGVLREEPPGTFSVIEEER
Sbjct: 661 PVQAVILLYFQDQASWTLEELSKAVKMPVALLRRRMSVWLQQGVLREEPPGTFSVIEEER 720
Query: 721 PQDRDNMVLIDSDDESDSGMASQADQKEEELLLFWTYIQAMLTNLESLSLDRIYNMLRMF 780
PQDRDNMVLIDSDDESDSGMASQADQKEEELLLFWTYIQAMLTNLESLSLDRIYNMLRMF
Sbjct: 721 PQDRDNMVLIDSDDESDSGMASQADQKEEELLLFWTYIQAMLTNLESLSLDRIYNMLRMF 780
Query: 781 VVTGPALAEIDLQELQGYLQKKVRDQQLVYSAGVYRLPKNCS 822
VVTGPALAEIDLQELQGYLQKKVRDQQLVYSAGVYRLPKNCS
Sbjct: 781 VVTGPALAEIDLQELQGYLQKKVRDQQLVYSAGVYRLPKNCS 822
>gi|169218008 PREDICTED: similar to anaphase-promoting complex
subunit 2 [Homo sapiens]
Length = 430
Score = 758 bits (1957), Expect = 0.0
Identities = 382/385 (99%), Positives = 382/385 (99%), Gaps = 3/385 (0%)
Query: 247 LHRLSLLERVSAEAVTTTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVGWLGKVFLQ 306
LHRLSLLERVSAEAVTTTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVGWLGKVFLQ
Sbjct: 24 LHRLSLLERVSAEAVTTTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVGWLGKVFLQ 83
Query: 307 DGPARPASPEAGNTLRRWRCHVQRFFYRIYASLRIEELFSIVRDFPDSRPAIEDLKYCLE 366
DGPARPASPEAGNTLRRWRCHVQRFFYRIYASLRIEELFSIVRD SRPAIEDLKYCLE
Sbjct: 84 DGPARPASPEAGNTLRRWRCHVQRFFYRIYASLRIEELFSIVRD---SRPAIEDLKYCLE 140
Query: 367 RTDQRQQLLVSLKAALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVILEVACEPIRR 426
RTDQRQQLLVSLKAALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVILEVACEPIRR
Sbjct: 141 RTDQRQQLLVSLKAALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVILEVACEPIRR 200
Query: 427 YLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPASLETGQDSEDDSGEPEDWVPDPVD 486
YLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPASLETGQDSEDDSGEPEDWVPDPVD
Sbjct: 201 YLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPASLETGQDSEDDSGEPEDWVPDPVD 260
Query: 487 ADPGKSSSKRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLK 546
ADPGKSSSKRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLK
Sbjct: 261 ADPGKSSSKRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLK 320
Query: 547 LRFGEAPMHFCEVMLKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKD 606
LRFGEAPMHFCEVMLKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKD
Sbjct: 321 LRFGEAPMHFCEVMLKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKD 380
Query: 607 EKLEVPEDIRAALEAYCKKYEQLKA 631
EKLEVPEDIRAALEAYCKKYEQLKA
Sbjct: 381 EKLEVPEDIRAALEAYCKKYEQLKA 405
>gi|57165424 cullin 4A isoform 1 [Homo sapiens]
Length = 759
Score = 65.5 bits (158), Expect = 2e-10
Identities = 52/200 (26%), Positives = 89/200 (44%), Gaps = 2/200 (1%)
Query: 497 RSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHF 556
R+ D I +L KD+F Y+ LA RLL S S + E + LK G A
Sbjct: 431 RTLDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSK 490
Query: 557 CEVMLKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIR 616
E M KDM S+ I + ++ + + + P + IL+ +WP + ++ + ++
Sbjct: 491 LEGMFKDMELSKDIMVHFKQHMQNQ--SDSGPIDLTVNILTMGYWPTYTPMEVHLTPEMI 548
Query: 617 AALEAYCKKYEQLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVILLYFQDQASW 676
E + Y + R L W+ TLG + E + V+ Q ++LL F + +
Sbjct: 549 KLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGF 608
Query: 677 TLEELSKAVKMPVALLRRRM 696
+ EE+ A + + LRR +
Sbjct: 609 SFEEIKMATGIEDSELRRTL 628
>gi|11140811 cullin 4A isoform 2 [Homo sapiens]
Length = 659
Score = 65.5 bits (158), Expect = 2e-10
Identities = 52/200 (26%), Positives = 89/200 (44%), Gaps = 2/200 (1%)
Query: 497 RSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHF 556
R+ D I +L KD+F Y+ LA RLL S S + E + LK G A
Sbjct: 331 RTLDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSK 390
Query: 557 CEVMLKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIR 616
E M KDM S+ I + ++ + + + P + IL+ +WP + ++ + ++
Sbjct: 391 LEGMFKDMELSKDIMVHFKQHMQNQ--SDSGPIDLTVNILTMGYWPTYTPMEVHLTPEMI 448
Query: 617 AALEAYCKKYEQLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVILLYFQDQASW 676
E + Y + R L W+ TLG + E + V+ Q ++LL F + +
Sbjct: 449 KLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGF 508
Query: 677 TLEELSKAVKMPVALLRRRM 696
+ EE+ A + + LRR +
Sbjct: 509 SFEEIKMATGIEDSELRRTL 528
>gi|121114302 cullin 4B isoform 2 [Homo sapiens]
Length = 895
Score = 62.8 bits (151), Expect = 1e-09
Identities = 53/189 (28%), Positives = 86/189 (45%), Gaps = 3/189 (1%)
Query: 508 IYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKDMADS 567
IYG KD+F Y+ LA RLL S S + E + LK G A E M KDM S
Sbjct: 579 IYG-KDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELS 637
Query: 568 RRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIRAALEAYCKKYE 627
+ I ++ + + V IL+ +WP + ++ +P ++ E + Y
Sbjct: 638 KDIMIQFKQYMQNQNVPGNIELTVN--ILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYL 695
Query: 628 QLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVILLYFQDQASWTLEELSKAVKM 687
+ R L W+ TLG + E + + V+ Q ++LL F + ++LEE+ +A +
Sbjct: 696 GKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGI 755
Query: 688 PVALLRRRM 696
LRR +
Sbjct: 756 EDGELRRTL 764
>gi|121114298 cullin 4B isoform 1 [Homo sapiens]
Length = 913
Score = 62.8 bits (151), Expect = 1e-09
Identities = 53/189 (28%), Positives = 86/189 (45%), Gaps = 3/189 (1%)
Query: 508 IYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKDMADS 567
IYG KD+F Y+ LA RLL S S + E + LK G A E M KDM S
Sbjct: 597 IYG-KDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELS 655
Query: 568 RRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIRAALEAYCKKYE 627
+ I ++ + + V IL+ +WP + ++ +P ++ E + Y
Sbjct: 656 KDIMIQFKQYMQNQNVPGNIELTVN--ILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYL 713
Query: 628 QLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVILLYFQDQASWTLEELSKAVKM 687
+ R L W+ TLG + E + + V+ Q ++LL F + ++LEE+ +A +
Sbjct: 714 GKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGI 773
Query: 688 PVALLRRRM 696
LRR +
Sbjct: 774 EDGELRRTL 782
>gi|32307161 cullin 1 [Homo sapiens]
Length = 776
Score = 59.7 bits (143), Expect = 1e-08
Identities = 43/195 (22%), Positives = 92/195 (47%), Gaps = 5/195 (2%)
Query: 512 KDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKDMADSRRIN 571
KD+F Y +LA RL+HQ S S + E + LK G + M +D+ S+ +N
Sbjct: 459 KDVFQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLN 518
Query: 572 ANIREEDEKRPAEEQPPFGVYAV-ILSSEFWPPFKDEKLEVPEDIRAALEAYCKKYEQLK 630
E+ +K +P +++ +LSS WP + +P ++ + + + Y
Sbjct: 519 ----EQFKKHLTNSEPLDLDFSIQVLSSGSWPFQQSCTFALPSELERSYQRFTAFYASRH 574
Query: 631 AMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVILLYFQDQASWTLEELSKAVKMPVA 690
+ R L+W + L + ++ + Q ILL + + ++T+++L+ + ++ +
Sbjct: 575 SGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQMAILLQYNTEDAYTVQQLTDSTQIKMD 634
Query: 691 LLRRRMSVWLQQGVL 705
+L + + + L+ +L
Sbjct: 635 ILAQVLQILLKSKLL 649
>gi|19482174 cullin 2 [Homo sapiens]
Length = 745
Score = 51.2 bits (121), Expect = 4e-06
Identities = 42/202 (20%), Positives = 82/202 (40%), Gaps = 5/202 (2%)
Query: 491 KSSSKRRSSDIISLLVSIY---GSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKL 547
K ++ D ++ ++++ KD+F Y +LA RL+H S S + E + LK
Sbjct: 404 KGMTENEVEDRLTSFITVFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQ 463
Query: 548 RFGEAPMHFCEVMLKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFK-- 605
G M DM+ S +N + + +L + WP +
Sbjct: 464 ACGYEFTSKLHRMYTDMSVSADLNNKFNNFIKNQDTVIDLGISFQIYVLQAGAWPLTQAP 523
Query: 606 DEKLEVPEDIRAALEAYCKKYEQLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAV 665
+P+++ +++ + Y Q + R L+W H L + + + VT Q
Sbjct: 524 SSTFAIPQELEKSVQMFELFYSQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMA 583
Query: 666 ILLYFQDQASWTLEELSKAVKM 687
+LL F + + + +EL + +M
Sbjct: 584 VLLAFNNSETVSYKELQDSTQM 605
>gi|4503165 cullin 3 [Homo sapiens]
Length = 768
Score = 42.4 bits (98), Expect = 0.002
Identities = 59/239 (24%), Positives = 93/239 (38%), Gaps = 32/239 (13%)
Query: 500 DIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEV 559
D +L KD+F Y+ LA RLL S S + E + LK G E
Sbjct: 413 DKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEG 472
Query: 560 MLKDMADSRRINANIREEDEKRPAEEQPPFGVYAV--ILSSEFWP-PFKDEKLEVPEDIR 616
M +DM+ S N + E + A GV +L++ +WP K +P R
Sbjct: 473 MFRDMSIS---NTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPR 529
Query: 617 AALEAYCKKYEQLKAMRTLSWKHTLGLVTMD------VELAD----------------RT 654
A E + + Y + R L+ +H +G ++ V+ D R
Sbjct: 530 HAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRK 589
Query: 655 LSVAVTPVQAVILLYFQDQASWTLEELSKAVKMPVALLRRRMSVWL----QQGVLREEP 709
+ V+ Q IL+ F ++ +T EE+ + +P L R + Q VL +EP
Sbjct: 590 HILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEP 648
>gi|40254446 Vasopressin-activated calcium-mobilizing receptor-1
[Homo sapiens]
Length = 780
Score = 41.2 bits (95), Expect = 0.004
Identities = 58/256 (22%), Positives = 108/256 (42%), Gaps = 30/256 (11%)
Query: 502 ISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLK-LRFGEAPMHFCEVM 560
+ L++ +KD+F+ +++ L RL+ S E E VE L+ + ++ M
Sbjct: 437 VLLVLKYVQNKDVFMRYHKAHLTRRLILDISADSEIEENMVEWLREVGMPADYVNKLARM 496
Query: 561 LKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEK-LEVPEDIRAAL 619
+D+ S +N +E K P V IL++ W ++ + +P ++ +
Sbjct: 497 FQDIKVSEDLNQAFKEM-HKNNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELEDLI 555
Query: 620 EAYCKKYEQLKAMRTLSWKHTL--GLVTMDVELADRTLSVAVTPVQAVILLYFQDQASWT 677
+ Y++ + R L W H + G++T E+ L V + + + + +
Sbjct: 556 PEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRPREKIS 615
Query: 678 LEELSKAVKMPVALLRRRMSVW-------LQQGVLREEP---------PGT-------FS 714
E L A ++P A LRR ++W L++ VL EP GT FS
Sbjct: 616 FENLKLATELPDAELRR--TLWSLVAFPKLKRQVLLYEPQVNSPKDFTEGTLFSVNQEFS 673
Query: 715 VIEEERPQDRDNMVLI 730
+I+ + Q R + LI
Sbjct: 674 LIKNAKVQKRGKINLI 689
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 37.4 bits (85), Expect = 0.057
Identities = 78/367 (21%), Positives = 147/367 (40%), Gaps = 63/367 (17%)
Query: 455 ELSKTDPASLETGQDSEDDSGEPEDWVPDPVDADPGKSS-SKRRSSDIISLLVSIYGSKD 513
EL+ TD LE+G+ ED++G + ++ + + S S ++ + ++ K+
Sbjct: 220 ELAITD---LESGR--EDEAGLHQSQAVHGLELEALRLSLSNMHTAQLELTQANLQKEKE 274
Query: 514 LFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKDMADSRRINAN 573
+ E R +L R + + R+ +ELL+ + EV+L+ ++ +
Sbjct: 275 TALTELREMLNSRRAQELALLQSRQQHELELLREQHAREKE---EVVLRCGQEAAELKEK 331
Query: 574 IREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIRAALEAYCKKYEQLKAMR 633
++ E EK V E W KD LE ++R L A K +++ ++
Sbjct: 332 LQSEMEKN---------AQIVKTLKEDWESEKDLCLE---NLRKELSA--KHQSEMEDLQ 377
Query: 634 TLSWKHTLGLVTMDVELADRTLSVAVTPVQAVILLYFQD--QASWTLEELSKAVKMPVAL 691
K ELA++ +A + FQD QA L L + +
Sbjct: 378 NQFQK----------ELAEQ---------RAELEKIFQDKNQAERALRNLESHHQAAIEK 418
Query: 692 LRRRMSVWLQQGVLREEPPGTFSVIEEERPQDRDNMVLIDSDDESDSGMASQADQKEEEL 751
LR + + G E+ F E+E+ + +N+ D ++ Q +EE+
Sbjct: 419 LREDLQS--EHGRCLEDLEFKFKESEKEKQLELENLQASYEDLKA---------QSQEEI 467
Query: 752 LLFWTYIQAMLTNLESLS------LDRIYNM--LRMFVVTGPALAEIDLQELQGYLQKKV 803
W+ + + T+ + LS L R + L E +L++L+ Y +KK+
Sbjct: 468 RRLWSQLDSARTSRQELSELHEQLLARTSRVEDLEQLKQREKTQHESELEQLRIYFEKKL 527
Query: 804 RDQQLVY 810
RD + Y
Sbjct: 528 RDAEKTY 534
>gi|194473673 hypothetical protein LOC100170765 [Homo sapiens]
Length = 130
Score = 35.4 bits (80), Expect = 0.22
Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 13/80 (16%)
Query: 672 DQASWTLEELSKAVKMPVALLRRRMSVWLQQGVLREEPPGTFSVIEEERPQDRDNMVLID 731
D W EEL ++ V LL + S+ L+ G LREE +++EEE +
Sbjct: 49 DSLLWIREELGNLRRVDVQLLGQLCSLGLEMGALREE---LVTILEEEE----------E 95
Query: 732 SDDESDSGMASQADQKEEEL 751
S E + Q Q+EE L
Sbjct: 96 SSKEEEEDQEPQRKQEEEHL 115
>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 32.0 bits (71), Expect = 2.4
Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 7/127 (5%)
Query: 419 VACEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPASLETGQDSEDDSGEPE 478
V CE + ++ D +R + +T D T L++ P S++ D G
Sbjct: 734 VTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKPGPVLNEGSPTSIQKLVPFSKDCGPDN 793
Query: 479 DWVPDPVDADPGKSSSKRRSSDII-----SLLVS--IYGSKDLFINEYRSLLADRLLHQF 531
+ V D V R++ ++ +LVS + K+ N SL+ R LH
Sbjct: 794 ECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLA 853
Query: 532 SFSPERE 538
S +P+RE
Sbjct: 854 SLTPQRE 860
>gi|110349721 titin isoform novex-3 [Homo sapiens]
Length = 5604
Score = 31.6 bits (70), Expect = 3.1
Identities = 33/130 (25%), Positives = 58/130 (44%), Gaps = 16/130 (12%)
Query: 604 FKDEKLEVPEDIRAAL---EAYCKKYEQLK------AMRTLSWKHTLGLVTMDVELADRT 654
+ +E LE DIR L E++ K ++K A +TL K L L+ E++ RT
Sbjct: 3672 YDEEYLESKSDIRGWLNVGESFLDKETKVKLQRLREARKTLMEKKKLSLLDTSSEISSRT 3731
Query: 655 LSVAVTPVQAVILLYFQDQASWTLEELSKAVKM-----PVALLRRRMSVWLQQGVLREEP 709
L + IL +D ++ +L+++ K+ + +S + Q + EE
Sbjct: 3732 LRSEASDKD--ILFSREDMKIRSMSDLAESYKVDHSAESIVQNPHALSNQMDQNIESEEL 3789
Query: 710 PGTFSVIEEE 719
P +F I +E
Sbjct: 3790 PTSFQTIVDE 3799
>gi|224994189 prominin 1 isoform 2 [Homo sapiens]
Length = 856
Score = 31.6 bits (70), Expect = 3.1
Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 17/110 (15%)
Query: 341 IEELFSIVRDFPDSRPAIEDLKYCL----ERTDQRQQLLVSLKAALETRL------LHPG 390
++E+ S+ +++ A+E++ L +++ Q L S+K +L + L +HP
Sbjct: 244 LDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSLRSSLNDPLCLVHPS 303
Query: 391 VNTCDIITLYISAIKA---LRVLDPSMVILEVACEPIRRYLRTREDTVRQ 437
TC+ I L +S + + LR L P ++ + + LRT D + Q
Sbjct: 304 SETCNSIRLSLSQLNSNPELRQLPP----VDAELDNVNNVLRTDLDGLVQ 349
>gi|224994199 prominin 1 isoform 4 [Homo sapiens]
Length = 825
Score = 31.6 bits (70), Expect = 3.1
Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 17/110 (15%)
Query: 341 IEELFSIVRDFPDSRPAIEDLKYCL----ERTDQRQQLLVSLKAALETRL------LHPG 390
++E+ S+ +++ A+E++ L +++ Q L S+K +L + L +HP
Sbjct: 244 LDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSLRSSLNDPLCLVHPS 303
Query: 391 VNTCDIITLYISAIKA---LRVLDPSMVILEVACEPIRRYLRTREDTVRQ 437
TC+ I L +S + + LR L P ++ + + LRT D + Q
Sbjct: 304 SETCNSIRLSLSQLNSNPELRQLPP----VDAELDNVNNVLRTDLDGLVQ 349
>gi|224994197 prominin 1 isoform 5 [Homo sapiens]
Length = 833
Score = 31.6 bits (70), Expect = 3.1
Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 17/110 (15%)
Query: 341 IEELFSIVRDFPDSRPAIEDLKYCL----ERTDQRQQLLVSLKAALETRL------LHPG 390
++E+ S+ +++ A+E++ L +++ Q L S+K +L + L +HP
Sbjct: 244 LDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSLRSSLNDPLCLVHPS 303
Query: 391 VNTCDIITLYISAIKA---LRVLDPSMVILEVACEPIRRYLRTREDTVRQ 437
TC+ I L +S + + LR L P ++ + + LRT D + Q
Sbjct: 304 SETCNSIRLSLSQLNSNPELRQLPP----VDAELDNVNNVLRTDLDGLVQ 349
>gi|224994195 prominin 1 isoform 6 [Homo sapiens]
Length = 834
Score = 31.6 bits (70), Expect = 3.1
Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 17/110 (15%)
Query: 341 IEELFSIVRDFPDSRPAIEDLKYCL----ERTDQRQQLLVSLKAALETRL------LHPG 390
++E+ S+ +++ A+E++ L +++ Q L S+K +L + L +HP
Sbjct: 253 LDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSLRSSLNDPLCLVHPS 312
Query: 391 VNTCDIITLYISAIKA---LRVLDPSMVILEVACEPIRRYLRTREDTVRQ 437
TC+ I L +S + + LR L P ++ + + LRT D + Q
Sbjct: 313 SETCNSIRLSLSQLNSNPELRQLPP----VDAELDNVNNVLRTDLDGLVQ 358
>gi|224994193 prominin 1 isoform 7 [Homo sapiens]
Length = 842
Score = 31.6 bits (70), Expect = 3.1
Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 17/110 (15%)
Query: 341 IEELFSIVRDFPDSRPAIEDLKYCL----ERTDQRQQLLVSLKAALETRL------LHPG 390
++E+ S+ +++ A+E++ L +++ Q L S+K +L + L +HP
Sbjct: 253 LDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSLRSSLNDPLCLVHPS 312
Query: 391 VNTCDIITLYISAIKA---LRVLDPSMVILEVACEPIRRYLRTREDTVRQ 437
TC+ I L +S + + LR L P ++ + + LRT D + Q
Sbjct: 313 SETCNSIRLSLSQLNSNPELRQLPP----VDAELDNVNNVLRTDLDGLVQ 358
>gi|224994191 prominin 1 isoform 2 [Homo sapiens]
Length = 856
Score = 31.6 bits (70), Expect = 3.1
Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 17/110 (15%)
Query: 341 IEELFSIVRDFPDSRPAIEDLKYCL----ERTDQRQQLLVSLKAALETRL------LHPG 390
++E+ S+ +++ A+E++ L +++ Q L S+K +L + L +HP
Sbjct: 244 LDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSLRSSLNDPLCLVHPS 303
Query: 391 VNTCDIITLYISAIKA---LRVLDPSMVILEVACEPIRRYLRTREDTVRQ 437
TC+ I L +S + + LR L P ++ + + LRT D + Q
Sbjct: 304 SETCNSIRLSLSQLNSNPELRQLPP----VDAELDNVNNVLRTDLDGLVQ 349
>gi|5174387 prominin 1 isoform 1 [Homo sapiens]
Length = 865
Score = 31.6 bits (70), Expect = 3.1
Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 17/110 (15%)
Query: 341 IEELFSIVRDFPDSRPAIEDLKYCL----ERTDQRQQLLVSLKAALETRL------LHPG 390
++E+ S+ +++ A+E++ L +++ Q L S+K +L + L +HP
Sbjct: 253 LDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSLRSSLNDPLCLVHPS 312
Query: 391 VNTCDIITLYISAIKA---LRVLDPSMVILEVACEPIRRYLRTREDTVRQ 437
TC+ I L +S + + LR L P ++ + + LRT D + Q
Sbjct: 313 SETCNSIRLSLSQLNSNPELRQLPP----VDAELDNVNNVLRTDLDGLVQ 358
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 31.2 bits (69), Expect = 4.1
Identities = 55/216 (25%), Positives = 84/216 (38%), Gaps = 22/216 (10%)
Query: 111 LLDAFGLLESRLDPYLRSLELLEKWTRLGLL-MGTGAQGLREEVHTMLRGVLFFSTPR-T 168
+LDA +L+ RSLE + +RLGL AQ L++ V ++ R V T
Sbjct: 1643 VLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGT 1702
Query: 169 FQEMIQRLYGCFLRVYMQS---KRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCS 225
Q ++RL G +V + K G T+ + R + L Q L A C
Sbjct: 1703 LQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHL-QKALTA-CE 1760
Query: 226 SDKQQCW-----CRQALEQFHQLSQVLHRLSL----------LERVSAEAVTTTLHQVTR 270
D+Q RQAL + + S L L+RV AE L +V R
Sbjct: 1761 HDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLR 1820
Query: 271 ERMEDRCRGEYERSFLREFHKWIERVVGWLGKVFLQ 306
+R E L++ + ++ +G L + Q
Sbjct: 1821 QRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQ 1856
>gi|156104883 guanine nucleotide binding protein (G protein), alpha
15 (Gq class) [Homo sapiens]
Length = 374
Score = 31.2 bits (69), Expect = 4.1
Identities = 16/43 (37%), Positives = 21/43 (48%)
Query: 239 QFHQLSQVLHRLSLLERVSAEAVTTTLHQVTRERMEDRCRGEY 281
+FH L ++ LS LER++ E T V R RM EY
Sbjct: 153 EFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEY 195
>gi|239755855 PREDICTED: hypothetical protein [Homo sapiens]
Length = 250
Score = 30.8 bits (68), Expect = 5.3
Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 4/78 (5%)
Query: 338 SLRIEELFSIVRDFPDSRPAIEDLKYCLERTDQRQQLLVSLKAALETRLLHPGVNTCDII 397
S R + L+ +D + + + +LKY + Q +LL LK + RLLH CDI+
Sbjct: 148 SQRHQMLYLRQKDANELKTILRELKYRIGI--QSAKLLRHLKQ--KDRLLHKVQRNCDIV 203
Query: 398 TLYISAIKALRVLDPSMV 415
T + A+ R SM+
Sbjct: 204 TACLQAVSQKRTWQNSML 221
>gi|239750363 PREDICTED: hypothetical protein XP_002347382 [Homo
sapiens]
Length = 250
Score = 30.8 bits (68), Expect = 5.3
Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 4/78 (5%)
Query: 338 SLRIEELFSIVRDFPDSRPAIEDLKYCLERTDQRQQLLVSLKAALETRLLHPGVNTCDII 397
S R + L+ +D + + + +LKY + Q +LL LK + RLLH CDI+
Sbjct: 148 SQRHQMLYLRQKDANELKTILRELKYRIGI--QSAKLLRHLKQ--KDRLLHKVQRNCDIV 203
Query: 398 TLYISAIKALRVLDPSMV 415
T + A+ R SM+
Sbjct: 204 TACLQAVSQKRTWQNSML 221
>gi|239744667 PREDICTED: hypothetical protein XP_002343220 [Homo
sapiens]
Length = 250
Score = 30.8 bits (68), Expect = 5.3
Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 4/78 (5%)
Query: 338 SLRIEELFSIVRDFPDSRPAIEDLKYCLERTDQRQQLLVSLKAALETRLLHPGVNTCDII 397
S R + L+ +D + + + +LKY + Q +LL LK + RLLH CDI+
Sbjct: 148 SQRHQMLYLRQKDANELKTILRELKYRIGI--QSAKLLRHLKQ--KDRLLHKVQRNCDIV 203
Query: 398 TLYISAIKALRVLDPSMV 415
T + A+ R SM+
Sbjct: 204 TACLQAVSQKRTWQNSML 221
>gi|157384971 cyclin G associated kinase [Homo sapiens]
Length = 1311
Score = 30.8 bits (68), Expect = 5.3
Identities = 20/86 (23%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
Query: 504 LLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKD 563
+L+ IY ++ ++ +A + Q F RN +K F + + C++ K
Sbjct: 640 VLIVIYHARSTLGGRLQAKMASMKMFQIQFHTGFVPRNATTVK--FAKYDLDACDIQEK- 696
Query: 564 MADSRRINANIREEDEKRPAEEQPPF 589
D ++N + E RP+ E PP+
Sbjct: 697 YPDLFQVNLEVEVEPRDRPSREAPPW 722
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 30.8 bits (68), Expect = 5.3
Identities = 38/168 (22%), Positives = 62/168 (36%), Gaps = 43/168 (25%)
Query: 455 ELSKTDPASLETGQDSEDDSGEPEDWVPDPVDADPGKSSSKRRSSDIISLLVSIYGSKDL 514
E K DP + G D S DPGK ++ R + G DL
Sbjct: 1539 EKEKGDPVKMSNGNDKVAPS------------KDPGKKDARPREK--------LLGDGDL 1578
Query: 515 FINEYRSLLA--DRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKDMADSRRINA 572
+ + +L+ D + + + ++ +E L+ R G+ + + K D R+
Sbjct: 1579 MMTSFERMLSQKDLEIEERHKRHKERMKQMEKLRHRSGDPKL---KEKAKPADDGRKKGL 1635
Query: 573 NIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIRAALE 620
+I PA++ P PPFKD+KL+ I A E
Sbjct: 1636 DI-------PAKKPPGLD-----------PPFKDKKLKESTPIPPAAE 1665
>gi|188219577 ring finger protein 19B isoform a [Homo sapiens]
Length = 732
Score = 30.8 bits (68), Expect = 5.3
Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 14/99 (14%)
Query: 532 SFSPE-REIRNVELLKLRFGEAPMHFCEVMLKDMADSRRINANIREEDEKRP----AEEQ 586
S++P+ RE N+E+ ++ P H+ V DS ++A + E +E+ +EE
Sbjct: 576 SYNPQDRECNNMEI-QVDIEAKPSHYQLVSGSSTEDSLHVHAQMAENEEEGSGGGGSEED 634
Query: 587 PPFGVYAV----ILSSEFWPPFKDEKLEVPEDIRAALEA 621
PP + L+S+ W D L PE IR+ LE+
Sbjct: 635 PPCRHQSCEQKDCLASKPW----DISLAQPESIRSDLES 669
>gi|148806925 EGF, latrophilin and seven transmembrane domain
containing 1 [Homo sapiens]
Length = 690
Score = 30.8 bits (68), Expect = 5.3
Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 38/135 (28%)
Query: 105 PQCLLLLLD--AFGLL-------ESRLDPYLRSLELLEKWTR-----LGLLMGTGAQGLR 150
P CL++L++ AFG++ + L P + E + R L LL T G+
Sbjct: 577 PACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVL 636
Query: 151 EEVHTMLRGVLFFSTPRTFQEMIQRLYGCFLRVYMQSKRKGEGGTDPELEGELDSRYARR 210
VH + F+ FQ M L+ C L SR +
Sbjct: 637 HVVHASVVTAYLFTVSNAFQGMFIFLFLCVL-----------------------SRKIQE 673
Query: 211 RYYRLLQS-PLCAGC 224
YYRL ++ P C GC
Sbjct: 674 EYYRLFKNVPCCFGC 688
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,920,688
Number of Sequences: 37866
Number of extensions: 1444562
Number of successful extensions: 4471
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 4444
Number of HSP's gapped (non-prelim): 44
length of query: 822
length of database: 18,247,518
effective HSP length: 111
effective length of query: 711
effective length of database: 14,044,392
effective search space: 9985562712
effective search space used: 9985562712
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.